# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Trypan_PARP PF05887.6 EIM78923.1 - 0.29 10.9 3.0 0.3 10.8 2.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 EIM78923.1 - 0.59 8.4 12.3 0.61 8.3 8.5 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Chromo PF00385.19 EIM78924.1 - 2e-06 27.3 0.4 2.5e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIM78924.1 - 0.065 12.9 0.4 0.088 12.5 0.3 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain XPG_I_2 PF12813.2 EIM78928.1 - 0.038 13.4 0.1 0.041 13.3 0.0 1.0 1 0 0 1 1 1 0 XPG domain containing Retrotrans_gag PF03732.12 EIM78933.1 - 2.2e-15 56.4 0.1 7.2e-15 54.8 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM78933.1 - 1.8e-05 24.4 9.9 0.0078 16.1 1.6 2.4 2 0 0 2 2 2 2 Zinc knuckle NPV_P10 PF05531.7 EIM78933.1 - 0.03 14.5 3.4 0.12 12.6 0.7 2.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Nudix_N_2 PF14803.1 EIM78933.1 - 0.095 12.4 3.3 0.2 11.3 1.8 1.9 2 0 0 2 2 2 0 Nudix N-terminal zf-CCHC_4 PF14392.1 EIM78933.1 - 0.16 11.6 4.6 3.3 7.4 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Reo_sigmaC PF04582.7 EIM78933.1 - 3.4 6.7 7.7 0.42 9.7 2.2 1.8 3 0 0 3 3 3 0 Reovirus sigma C capsid protein RNase_H PF00075.19 EIM78934.1 - 0.00018 21.8 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Dehalogenase PF13486.1 EIM78936.1 - 0.45 9.9 4.1 0.44 9.9 0.2 2.0 1 1 0 2 2 2 0 Reductive dehalogenase subunit Prok-TraM PF09228.5 EIM78936.1 - 0.54 10.4 4.4 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Glypican PF01153.14 EIM78937.1 - 0.026 13.1 0.5 0.035 12.7 0.4 1.1 1 0 0 1 1 1 0 Glypican CDC45 PF02724.9 EIM78937.1 - 0.066 11.2 3.1 0.088 10.8 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EIM78937.1 - 2 7.3 7.1 2.7 6.9 5.0 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 EIM78937.1 - 2.3 7.2 12.9 3.5 6.6 9.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.7 EIM78937.1 - 4.8 5.4 9.4 6.9 4.9 6.5 1.1 1 0 0 1 1 1 0 Mpp10 protein COPI_C PF06957.6 EIM78937.1 - 7.5 4.9 5.9 11 4.4 4.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 EIM78937.1 - 9.2 4.0 13.1 12 3.6 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Asp_protease_2 PF13650.1 EIM78938.1 - 0.00018 21.9 0.0 0.00018 21.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIM78938.1 - 0.00066 19.6 0.0 0.0007 19.5 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIM78938.1 - 0.0094 15.7 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIM78939.1 - 3.6e-15 55.7 0.3 1.5e-14 53.8 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM78939.1 - 1.2e-05 25.0 9.9 0.0061 16.4 1.6 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.1 EIM78939.1 - 0.029 14.0 1.8 0.089 12.5 1.3 1.8 1 1 0 1 1 1 0 Nudix N-terminal zf-CCHC_4 PF14392.1 EIM78939.1 - 0.097 12.3 4.6 2.6 7.8 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF605 PF04652.11 EIM78940.1 - 1.2 8.5 16.3 1.3 8.3 11.3 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EIM78940.1 - 9.1 4.3 11.1 10 4.2 7.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CHCH PF06747.8 EIM78941.1 - 0.1 12.5 0.3 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 CHCH domain Hepcidin PF06446.7 EIM78952.1 - 0.13 12.7 6.8 0.37 11.2 4.7 1.8 1 0 0 1 1 1 0 Hepcidin TrkA_C PF02080.16 EIM78952.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain THF_DHG_CYH_C PF02882.14 EIM78953.1 - 3.9e-15 55.2 0.0 4.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DivIC PF04977.10 EIM78957.1 - 0.023 14.1 0.8 0.049 13.1 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 EIM78957.1 - 0.16 11.8 1.4 0.28 11.0 0.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF2396 PF09654.5 EIM78958.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) DNA_pol3_gamma3 PF12169.3 EIM78959.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III PH_9 PF15410.1 EIM78959.1 - 0.13 12.4 1.1 0.35 11.0 0.8 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Patatin PF01734.17 EIM78961.1 - 3.3e-29 102.2 0.0 5.3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Coagulase PF08764.5 EIM78964.1 - 0.01 15.8 0.3 0.013 15.4 0.2 1.1 1 0 0 1 1 1 1 Staphylococcus aureus coagulase DUF2373 PF10180.4 EIM78964.1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) PBP PF01161.15 EIM78965.1 - 2e-15 56.8 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3846 PF12957.2 EIM78965.1 - 0.0042 16.7 0.0 0.89 9.3 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3846) PBP PF01161.15 EIM78966.1 - 6e-14 52.1 0.0 7.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Retrotrans_gag PF03732.12 EIM78967.1 - 7.9e-15 54.7 0.3 3.4e-14 52.6 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM78967.1 - 0.034 14.0 4.8 0.062 13.2 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Nudix_N_2 PF14803.1 EIM78967.1 - 0.092 12.4 3.1 0.31 10.7 2.1 1.9 1 1 0 1 1 1 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 EIM78967.1 - 0.26 11.2 2.2 0.47 10.4 1.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DFP PF04127.10 EIM78968.1 - 0.076 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ribonuc_red_sm PF00268.16 EIM78968.1 - 0.086 11.8 0.2 0.16 10.9 0.2 1.5 1 1 0 1 1 1 0 Ribonucleotide reductase, small chain 2OG-FeII_Oxy_3 PF13640.1 EIM78970.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MyTH4 PF00784.12 EIM78972.1 - 0.17 11.8 1.5 3.2 7.7 0.0 2.9 3 0 0 3 3 3 0 MyTH4 domain SIR2 PF02146.12 EIM78975.1 - 9.8e-30 103.5 0.0 6.2e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family DDE_3 PF13358.1 EIM78976.1 - 0.0042 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIM78977.1 - 1.4e-07 31.1 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF814 PF05670.8 EIM78979.1 - 8.6e-23 80.0 0.0 2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Tnp_P_element_C PF12596.3 EIM78979.1 - 0.069 13.4 0.8 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 87kDa Transposase zf-CCHC PF00098.18 EIM78980.1 - 0.0004 20.1 2.6 0.00071 19.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIM78980.1 - 0.0094 15.6 1.3 0.029 14.0 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle DZR PF12773.2 EIM78981.1 - 0.00051 19.8 9.9 0.0068 16.1 0.5 2.6 3 0 0 3 3 3 2 Double zinc ribbon HypA PF01155.14 EIM78981.1 - 0.0098 15.5 0.6 0.0098 15.5 0.4 2.3 2 1 0 2 2 2 1 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EIM78981.1 - 0.059 13.2 10.2 0.074 12.9 0.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger FYDLN_acid PF09538.5 EIM78981.1 - 0.06 13.9 1.5 0.12 12.9 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cytochrom_c3_2 PF14537.1 EIM78981.1 - 0.062 13.6 8.7 0.086 13.1 5.5 1.6 1 1 0 1 1 1 0 Cytochrome c3 A2L_zn_ribbon PF08792.5 EIM78981.1 - 0.93 9.0 7.2 2.7 7.5 0.1 3.3 2 1 1 3 3 3 0 A2L zinc ribbon domain zf-dskA_traR PF01258.12 EIM78981.1 - 3.5 7.4 6.7 2.8 7.7 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger DUF4230 PF14014.1 EIM78982.1 - 0.26 11.1 0.0 0.5 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) AAA_22 PF13401.1 EIM78984.1 - 0.00081 19.5 0.0 0.37 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM78984.1 - 0.0035 17.0 0.4 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF2396 PF09654.5 EIM78984.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) WSK PF03832.8 EIM78984.1 - 1.2 8.5 5.9 4.8 6.6 1.0 2.6 2 0 0 2 2 2 0 WSK motif CIDE-N PF02017.10 EIM78987.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 CIDE-N domain UBN2_2 PF14227.1 EIM78988.1 - 2e-12 46.7 0.4 3.3e-12 46.0 0.3 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM78988.1 - 1.4e-08 34.5 0.4 7.5e-08 32.1 0.3 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Phg_2220_C PF09524.5 EIM78988.1 - 0.11 12.4 0.0 0.64 10.0 0.0 2.0 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) His_Phos_1 PF00300.17 EIM78988.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Retrotrans_gag PF03732.12 EIM78989.1 - 2.1e-07 30.9 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM78989.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle BTB PF00651.26 EIM78991.1 - 0.00071 19.5 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF3154 PF11351.3 EIM78991.1 - 0.0086 15.8 0.5 0.057 13.1 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3154) SFTA2 PF15210.1 EIM78992.1 - 0.00014 21.3 1.7 29 4.3 0.0 5.6 5 1 1 6 6 6 1 Surfactant-associated protein 2 HpaB PF03241.8 EIM78992.1 - 0.0021 16.9 0.0 1.8 7.3 0.0 2.5 2 1 0 2 2 2 2 4-hydroxyphenylacetate 3-hydroxylase C terminal BCL9 PF11502.3 EIM78992.1 - 0.038 13.5 0.5 91 2.7 0.0 4.5 6 0 0 6 6 6 0 B-cell lymphoma 9 protein TetM_leader PF08076.6 EIM78992.1 - 0.35 10.4 7.0 31 4.2 0.2 4.7 5 0 0 5 5 5 0 Tetracycline resistance determinant leader peptide Sprouty PF05210.8 EIM78992.1 - 3.9 7.5 28.9 0.56 10.2 2.0 3.4 2 2 1 3 3 3 0 Sprouty protein (Spry) Ldh_1_C PF02866.13 EIM78994.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 1 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain MULE PF10551.4 EIM78997.1 - 0.00047 20.2 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Retrotrans_gag PF03732.12 EIM78999.1 - 8.9e-15 54.5 0.2 4e-14 52.4 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM78999.1 - 1.2e-05 25.0 9.9 0.0061 16.4 1.6 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.1 EIM78999.1 - 0.028 14.0 1.8 0.089 12.5 1.3 1.8 1 1 0 1 1 1 0 Nudix N-terminal zf-CCHC_4 PF14392.1 EIM78999.1 - 0.098 12.3 4.6 2.6 7.8 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 EIM79000.1 - 1.4e-06 27.6 0.0 2.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM79000.1 - 2.1e-05 23.9 0.0 3.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM79000.1 - 2.2e-05 24.3 0.2 9.1e-05 22.2 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM79000.1 - 3.4e-05 22.9 0.0 5.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIM79000.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EIM79000.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EIM79000.1 - 0.028 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EIM79000.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WaaY PF06176.6 EIM79000.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_C39_2 PF13529.1 EIM79002.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family DDE_Tnp_4 PF13359.1 EIM79004.1 - 3.4e-22 78.7 0.0 4.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.1 EIM79005.1 - 0.2 11.8 1.4 0.28 11.3 0.2 1.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain dsrm PF00035.20 EIM79006.1 - 3.7e-08 33.8 0.2 6.5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EIM79006.1 - 9e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM79006.1 - 0.16 12.4 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain Mito_fiss_reg PF05308.6 EIM79006.1 - 0.22 10.8 7.7 0.3 10.4 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Retrotrans_gag PF03732.12 EIM79007.1 - 5.7e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Bac_transf PF02397.11 EIM79007.1 - 0.019 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase zf-CCHC PF00098.18 EIM79007.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 EIM79008.1 - 1.7e-07 30.9 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIM79008.1 - 3e-05 24.4 0.0 3e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIM79008.1 - 0.00034 20.5 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2E PF12382.3 EIM79008.1 - 0.072 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase NESP55 PF06390.7 EIM79009.1 - 0.9 8.8 12.1 1.1 8.6 8.1 1.3 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Dimer_Tnp_hAT PF05699.9 EIM79011.1 - 2.8e-06 26.8 0.3 0.033 13.8 0.0 3.0 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region ROKNT PF08067.6 EIM79021.1 - 0.18 11.6 1.4 0.34 10.8 0.8 1.6 1 1 0 1 1 1 0 ROKNT (NUC014) domain PSS PF03034.10 EIM79021.1 - 1.1 8.6 6.6 1.7 8.0 4.5 1.2 1 0 0 1 1 1 0 Phosphatidyl serine synthase MULE PF10551.4 EIM79023.1 - 1.1e-06 28.7 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM79023.1 - 2.4e-05 23.6 0.0 4.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger HeLo PF14479.1 EIM79023.1 - 0.013 15.2 0.2 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF4218 PF13960.1 EIM79024.1 - 3.6e-08 32.8 0.0 1.7e-07 30.6 0.0 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIM79025.1 - 8.4e-08 31.5 0.0 1.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 CDC45 PF02724.9 EIM79029.1 - 0.21 9.5 3.2 0.36 8.8 0.2 2.1 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.1 EIM79029.1 - 0.94 9.8 6.7 2.9 8.2 4.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF869 PF05911.6 EIM79032.1 - 0.001 17.4 8.2 0.0016 16.8 5.7 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EIM79032.1 - 0.0016 18.1 11.9 0.023 14.4 2.8 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIM79032.1 - 0.0028 16.7 13.8 0.0053 15.8 9.6 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 EIM79032.1 - 0.011 15.3 15.9 0.019 14.5 11.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF812 PF05667.6 EIM79032.1 - 0.024 13.1 10.0 0.053 12.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EIM79032.1 - 0.03 14.6 9.0 1.2 9.4 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EzrA PF06160.7 EIM79032.1 - 0.055 11.6 8.4 0.082 11.0 5.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EIM79032.1 - 0.1 11.7 3.7 0.16 11.0 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Peptidase_S46 PF10459.4 EIM79032.1 - 0.91 7.8 10.2 1.4 7.2 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 EIM79032.1 - 1.4 8.4 25.7 78 2.7 17.8 2.4 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 EIM79032.1 - 2 8.4 9.2 12 5.9 0.1 2.8 1 1 1 2 2 2 0 DivIVA protein TBPIP PF07106.8 EIM79032.1 - 2.1 7.8 10.1 4.4 6.8 1.0 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EIM79032.1 - 2.7 8.1 7.2 5.9 7.0 5.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PspB PF06667.7 EIM79032.1 - 6.1 6.8 5.7 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Mnd1 PF03962.10 EIM79032.1 - 6.7 6.3 15.2 1.5 8.4 6.9 2.1 1 1 1 2 2 2 0 Mnd1 family CobT PF06213.7 EIM79033.1 - 0.0094 15.1 6.4 0.017 14.2 4.5 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EIM79033.1 - 0.15 10.5 7.2 0.27 9.6 5.0 1.3 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EIM79033.1 - 0.17 11.3 8.1 0.31 10.5 5.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EIM79033.1 - 1.6 6.5 9.4 2.6 5.8 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 EIM79033.1 - 3.2 5.9 12.0 5 5.3 8.3 1.1 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 EIM79033.1 - 5 6.2 7.9 11 5.1 5.5 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EIM79033.1 - 5.5 6.5 9.4 11 5.5 6.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Dimer_Tnp_hAT PF05699.9 EIM79034.1 - 1.7e-12 46.8 0.1 1.8e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PBP PF01161.15 EIM79036.1 - 6.1e-16 58.5 0.0 6.4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ALF PF03752.8 EIM79036.1 - 0.14 11.9 0.1 3.9 7.4 0.0 2.5 2 1 1 3 3 3 0 Short repeats of unknown function CAP_N PF01213.14 EIM79037.1 - 0.72 9.0 10.3 0.14 11.4 4.6 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DDE_1 PF03184.14 EIM79038.1 - 5.1e-07 29.0 0.0 6.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_19 PF13245.1 EIM79040.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM79040.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM79040.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 EIM79040.1 - 0.25 9.9 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Helicase_C PF00271.26 EIM79041.1 - 9.9e-11 41.3 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM79041.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SMC_N PF02463.14 EIM79045.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ribosomal_L36e PF01158.13 EIM79045.1 - 0.037 13.9 1.2 0.067 13.1 0.0 1.9 2 1 0 2 2 2 0 Ribosomal protein L36e Atg14 PF10186.4 EIM79045.1 - 0.12 11.3 7.4 0.15 11.0 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 EIM79045.1 - 5 7.3 11.8 7.6 6.8 8.2 1.4 1 1 0 1 1 1 0 AAA domain Cauli_VI PF01693.11 EIM79046.1 - 2.5e-08 33.8 1.9 0.00061 19.7 0.1 3.6 4 0 0 4 4 4 2 Caulimovirus viroplasmin GRA6 PF05084.8 EIM79053.1 - 0.064 12.7 0.1 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DDE_3 PF13358.1 EIM79054.1 - 1.6e-08 34.4 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DivIC PF04977.10 EIM79056.1 - 0.0058 16.0 1.8 0.01 15.3 1.2 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 EIM79056.1 - 0.047 13.9 1.6 0.086 13.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EIM79056.1 - 0.11 12.4 0.2 0.56 10.2 0.1 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Orthopox_F8 PF05886.6 EIM79057.1 - 0.21 11.4 1.1 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Transposase_21 PF02992.9 EIM79058.1 - 7.8e-07 28.4 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIM79059.1 - 2e-08 33.7 0.8 1.3e-07 31.0 0.0 2.6 3 1 0 4 4 4 1 Domain of unknown function (DUF4218) bZIP_C PF12498.3 EIM79060.1 - 1.9 9.7 8.1 0.57 11.4 1.1 2.4 1 1 1 2 2 2 0 Basic leucine-zipper C terminal zf-CCHC PF00098.18 EIM79061.1 - 2.3e-07 30.3 3.8 4.6e-07 29.4 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIM79061.1 - 0.00044 20.2 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIM79061.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.1 EIM79061.1 - 0.05 13.3 0.3 0.19 11.4 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIM79061.1 - 0.058 13.0 0.3 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM79061.1 - 0.059 12.8 2.7 0.13 11.7 1.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peptidase_A2B PF12384.3 EIM79061.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase ADH_N_assoc PF13823.1 EIM79061.1 - 0.17 11.5 0.8 0.5 10.0 0.5 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated V-SNARE_C PF12352.3 EIM79065.1 - 0.044 13.8 0.2 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus TBCA PF02970.11 EIM79065.1 - 0.094 12.8 0.3 0.094 12.8 0.2 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor A eIF_4EBP PF05456.6 EIM79065.1 - 0.16 11.6 3.4 0.54 9.9 2.3 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MCLC PF05934.6 EIM79065.1 - 0.31 9.2 9.6 0.56 8.4 6.7 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Tet_JBP PF12851.2 EIM79067.1 - 0.0012 18.2 0.1 0.0022 17.3 0.1 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF1866 PF08952.6 EIM79067.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Gemini_C4 PF01492.12 EIM79069.1 - 0.053 13.2 6.6 0.25 11.0 4.6 2.2 1 0 0 1 1 1 0 Geminivirus C4 protein DEAD PF00270.24 EIM79071.1 - 6.7e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 EIM79077.1 - 2.9e-05 23.1 0.0 0.00029 19.8 0.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 EIM79078.1 - 1.6e-13 50.3 0.0 1.9e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIM79078.1 - 2e-10 40.5 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM79078.1 - 0.00016 21.3 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EIM79078.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain ArgK PF03308.11 EIM79078.1 - 0.0021 16.9 0.0 0.0028 16.4 0.0 1.1 1 0 0 1 1 1 1 ArgK protein ATP_bind_1 PF03029.12 EIM79078.1 - 0.0026 17.3 0.1 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EIM79078.1 - 0.0059 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 EIM79078.1 - 0.008 14.8 0.1 0.023 13.3 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 EIM79078.1 - 0.0082 15.9 0.1 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 EIM79078.1 - 0.014 14.2 0.1 0.077 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 EIM79078.1 - 0.017 15.2 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM79078.1 - 0.051 13.7 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM79078.1 - 0.056 13.4 0.0 0.08 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 EIM79078.1 - 0.079 12.1 0.3 0.33 10.1 0.0 1.9 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EIM79078.1 - 0.094 12.4 0.1 0.22 11.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIM79078.1 - 0.097 12.5 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 EIM79080.1 - 5.4e-10 39.3 0.0 6.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RNF111_N PF15303.1 EIM79080.1 - 0.088 12.3 0.3 5.4 6.4 0.0 2.1 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus PGA2 PF07543.7 EIM79084.1 - 0.0013 18.4 4.1 0.0015 18.3 2.8 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 BSP_II PF05432.6 EIM79084.1 - 0.018 14.3 7.5 0.018 14.3 5.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) VID27 PF08553.5 EIM79084.1 - 0.028 12.6 5.5 0.026 12.7 3.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ribosomal_60s PF00428.14 EIM79084.1 - 0.048 14.0 8.9 0.066 13.6 6.2 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_RNA_Pol_19 PF05320.7 EIM79084.1 - 0.069 12.8 3.2 0.089 12.5 2.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit APG6 PF04111.7 EIM79084.1 - 0.17 10.8 3.0 0.2 10.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RXT2_N PF08595.6 EIM79084.1 - 0.23 11.2 2.4 0.3 10.8 1.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EIM79084.1 - 0.24 10.8 10.1 0.31 10.5 7.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4246 PF14033.1 EIM79084.1 - 0.27 9.7 2.8 0.3 9.6 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Myc_N PF01056.13 EIM79084.1 - 0.28 10.3 7.3 0.3 10.2 5.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.3 EIM79084.1 - 0.3 11.7 14.5 0.063 13.9 8.0 1.6 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.6 EIM79084.1 - 0.31 9.0 1.6 0.33 9.0 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 EIM79084.1 - 0.57 9.1 2.9 0.59 9.0 2.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.7 EIM79084.1 - 0.57 8.8 6.6 0.59 8.8 4.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PBP1_TM PF14812.1 EIM79084.1 - 0.6 10.4 4.1 0.95 9.8 2.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3682 PF12446.3 EIM79084.1 - 0.95 9.7 10.0 1.8 8.8 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Daxx PF03344.10 EIM79084.1 - 1.2 7.5 8.4 1.2 7.5 5.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF740 PF05340.7 EIM79084.1 - 1.9 6.7 7.2 2 6.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) NOA36 PF06524.7 EIM79084.1 - 2 7.5 4.9 2.7 7.1 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.8 EIM79084.1 - 2.1 6.9 9.3 2.2 6.9 6.4 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 EIM79084.1 - 2.8 5.7 9.6 2.8 5.7 6.6 1.0 1 0 0 1 1 1 0 Nop14-like family Exonuc_VII_L PF02601.10 EIM79085.1 - 0.015 14.5 1.0 4 6.5 0.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.7 EIM79087.1 - 0.0016 18.2 0.7 0.0033 17.1 0.5 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 EIM79087.1 - 0.0035 17.7 0.9 0.009 16.4 0.6 1.7 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EIM79087.1 - 0.0057 16.6 0.8 0.012 15.5 0.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EIM79087.1 - 0.018 14.6 0.9 0.031 13.8 0.6 1.3 1 0 0 1 1 1 0 IncA protein HOOK PF05622.7 EIM79087.1 - 0.07 10.9 2.1 0.1 10.4 1.4 1.1 1 0 0 1 1 1 0 HOOK protein DUF702 PF05142.7 EIM79090.1 - 0.0023 18.1 0.1 0.0061 16.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF702) AbfB PF05270.8 EIM79090.1 - 0.058 13.0 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B (ABFB) FdhE PF04216.7 EIM79091.1 - 2.3 7.8 4.9 19 4.8 0.5 2.6 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation Daxx PF03344.10 EIM79095.1 - 0.00031 19.3 11.6 0.00056 18.5 8.0 1.3 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EIM79095.1 - 1.6 6.7 9.2 2.9 5.8 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.2 EIM79097.1 - 0.0019 17.8 0.2 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM79097.1 - 0.16 11.6 3.6 1.7 8.3 0.1 3.5 3 0 0 3 3 3 0 F-box domain DUF3987 PF13148.1 EIM79099.1 - 3.1 6.2 9.8 0.1 11.1 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Helitron_like_N PF14214.1 EIM79100.1 - 2.7e-08 33.7 0.0 3.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIM79103.1 - 6.6e-05 22.0 0.1 0.0054 15.7 0.1 2.7 2 1 0 2 2 2 2 PIF1-like helicase KduI PF04962.7 EIM79104.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family PRY PF13765.1 EIM79108.1 - 0.04 13.4 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 SPRY-associated domain F-box PF00646.28 EIM79110.1 - 0.00016 21.2 0.1 0.00037 20.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM79110.1 - 0.00023 20.7 0.5 0.00039 20.0 0.3 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EIM79110.1 - 0.24 11.4 0.5 1.1 9.2 0.3 2.2 3 0 0 3 3 3 0 PRANC domain SlyX PF04102.7 EIM79111.1 - 0.68 10.3 2.7 22 5.5 0.1 3.0 2 1 1 3 3 3 0 SlyX dsrm PF00035.20 EIM79113.1 - 0.0033 17.9 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif HEAT PF02985.17 EIM79117.1 - 5.2e-07 29.2 0.4 0.00082 19.2 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EIM79117.1 - 0.00035 20.8 0.0 0.53 10.6 0.0 2.7 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EIM79117.1 - 0.11 12.8 0.0 0.41 10.9 0.0 1.9 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 EIM79117.1 - 0.21 12.1 0.9 15 6.2 0.1 3.0 1 1 2 3 3 3 0 HEAT-like repeat Utp12 PF04003.7 EIM79118.1 - 0.07 13.0 0.2 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family FIBP PF05427.6 EIM79120.1 - 0.49 9.5 0.0 0.88 8.7 0.0 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) V-SNARE PF05008.10 EIM79121.1 - 0.0039 17.3 1.8 3.8 7.7 0.0 2.9 2 0 0 2 2 2 2 Vesicle transport v-SNARE protein N-terminus SAB PF04382.8 EIM79121.1 - 0.084 12.5 2.5 4.5 7.0 0.3 2.9 2 0 0 2 2 2 0 SAB domain p450 PF00067.17 EIM79122.1 - 3.5e-72 243.3 0.0 1.1e-71 241.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM79123.1 - 1.1e-46 159.3 0.0 1.3e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIM79125.1 - 5.3e-38 130.6 45.5 5.3e-38 130.6 31.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM79125.1 - 3.4e-18 65.1 21.4 1.3e-17 63.2 14.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM79125.1 - 1.9e-14 53.1 14.0 1.9e-14 53.1 9.7 3.1 1 1 0 3 3 3 1 Sugar (and other) transporter Terpene_synth_C PF03936.11 EIM79126.1 - 5.8e-08 32.2 0.1 9.7e-08 31.5 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DNA_ligase_OB_2 PF14743.1 EIM79127.1 - 9.3e-20 70.0 0.1 1.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 EIM79127.1 - 2.7e-12 46.5 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain adh_short PF00106.20 EIM79131.1 - 5.8e-18 65.3 0.0 9.8e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM79131.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM79131.1 - 0.00045 19.7 0.0 0.00077 18.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM79131.1 - 0.00062 19.8 0.0 0.00076 19.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EIM79131.1 - 0.005 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EIM79131.1 - 0.0091 16.1 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIM79131.1 - 0.027 13.4 0.1 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HTH_Tnp_1 PF01527.15 EIM79131.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Transposase NmrA PF05368.8 EIM79131.1 - 0.12 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Piwi PF02171.12 EIM79132.1 - 2.7e-15 56.1 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIM79132.1 - 8.6e-07 28.2 0.0 2.9e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Fasciclin PF02469.17 EIM79135.1 - 0.052 13.5 0.1 1.2 9.1 0.0 2.2 1 1 0 2 2 2 0 Fasciclin domain DUF2317 PF10079.4 EIM79138.1 - 0.00029 19.5 2.8 0.00036 19.2 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) DUF4455 PF14643.1 EIM79138.1 - 0.00087 18.0 4.4 0.0011 17.6 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF948 PF06103.6 EIM79138.1 - 0.0014 18.4 1.8 0.37 10.6 0.2 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EIM79138.1 - 0.0019 17.4 1.9 0.0023 17.1 1.3 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Filament PF00038.16 EIM79138.1 - 0.0033 16.9 3.9 0.0045 16.4 2.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein Sipho_Gp157 PF05565.6 EIM79138.1 - 0.0036 16.9 0.1 0.005 16.4 0.1 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 Syntaxin PF00804.20 EIM79138.1 - 0.0036 17.4 1.1 0.012 15.7 0.7 2.0 1 1 0 1 1 1 1 Syntaxin Atg14 PF10186.4 EIM79138.1 - 0.0048 15.8 2.7 0.0067 15.4 1.9 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 EIM79138.1 - 0.0067 15.8 1.1 0.0087 15.4 0.8 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF869 PF05911.6 EIM79138.1 - 0.0085 14.3 4.4 0.01 14.1 3.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Baculo_PEP_C PF04513.7 EIM79138.1 - 0.014 15.2 1.6 0.035 13.9 1.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EIM79138.1 - 0.024 14.9 1.8 0.036 14.3 0.9 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Lzipper-MIP1 PF14389.1 EIM79138.1 - 0.025 14.6 2.9 0.044 13.8 1.6 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Nsp1_C PF05064.8 EIM79138.1 - 0.032 13.8 1.7 0.063 12.9 1.1 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region IFT57 PF10498.4 EIM79138.1 - 0.039 12.6 2.3 0.051 12.3 1.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UBN2 PF14223.1 EIM79138.1 - 0.04 13.7 1.0 0.13 12.0 0.5 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Fzo_mitofusin PF04799.8 EIM79138.1 - 0.048 13.0 5.6 0.6 9.4 0.2 2.1 1 1 1 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.10 EIM79138.1 - 0.052 12.7 2.9 0.068 12.3 2.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMCO5 PF14992.1 EIM79138.1 - 0.055 12.5 3.7 0.066 12.3 2.6 1.1 1 0 0 1 1 1 0 TMCO5 family AAA_13 PF13166.1 EIM79138.1 - 0.056 11.8 1.1 0.065 11.6 0.8 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EIM79138.1 - 0.072 12.8 1.7 0.63 9.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EIM79138.1 - 0.1 12.1 2.4 0.14 11.6 1.7 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4239 PF14023.1 EIM79138.1 - 0.11 11.8 0.8 0.15 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3552 PF12072.3 EIM79138.1 - 0.12 11.5 3.3 0.32 10.1 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) HalX PF08663.5 EIM79138.1 - 0.16 11.9 4.6 0.13 12.2 1.1 2.1 1 1 1 2 2 2 0 HalX domain DUF848 PF05852.6 EIM79138.1 - 0.17 11.7 2.7 0.31 10.8 1.9 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TBCA PF02970.11 EIM79138.1 - 0.19 11.8 1.7 0.52 10.4 0.9 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor A Muted PF14942.1 EIM79138.1 - 0.19 11.5 6.6 0.27 11.0 3.7 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Phage_GPO PF05929.6 EIM79138.1 - 0.2 10.8 3.8 0.26 10.4 2.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Lectin_N PF03954.9 EIM79138.1 - 0.21 10.9 3.1 1.5 8.1 0.8 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Apolipoprotein PF01442.13 EIM79138.1 - 0.23 10.9 4.9 0.39 10.2 3.4 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 EIM79138.1 - 0.23 10.0 4.4 0.5 8.9 3.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.19 EIM79138.1 - 0.23 11.1 2.1 0.57 9.8 0.4 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.2 EIM79138.1 - 0.28 11.0 6.2 0.66 9.8 4.3 1.7 1 1 0 1 1 1 0 Tropomyosin like MbeD_MobD PF04899.7 EIM79138.1 - 0.35 10.8 3.7 1.9 8.4 1.3 2.5 1 1 1 2 2 2 0 MbeD/MobD like COG5 PF10392.4 EIM79138.1 - 0.38 10.7 3.3 0.72 9.8 2.0 1.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TPR_MLP1_2 PF07926.7 EIM79138.1 - 0.39 10.4 5.0 0.67 9.7 3.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EIM79138.1 - 0.46 10.0 6.1 1.3 8.5 4.3 1.7 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EIM79138.1 - 0.88 9.4 4.4 0.51 10.1 0.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EIM79138.1 - 1.2 8.8 4.1 0.98 9.1 0.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Spectrin PF00435.16 EIM79138.1 - 1.3 9.3 5.9 1.5 9.1 2.6 2.3 2 1 0 2 2 1 0 Spectrin repeat DEAD PF00270.24 EIM79139.1 - 0.00012 21.5 0.0 0.00042 19.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Rap1_C PF11626.3 EIM79139.1 - 0.015 15.1 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Helicase_C PF00271.26 EIM79140.1 - 0.0032 17.3 0.0 0.021 14.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Cauli_VI PF01693.11 EIM79141.1 - 0.0013 18.6 0.2 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin SLX9 PF15341.1 EIM79142.1 - 0.13 12.7 2.4 0.24 11.8 0.6 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF3194 PF11419.3 EIM79144.1 - 0.1 12.7 3.9 0.17 12.1 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Mif2_N PF15624.1 EIM79144.1 - 6.1 7.4 11.4 15 6.1 7.3 2.0 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Abhydrolase_5 PF12695.2 EIM79146.1 - 2.8e-05 23.8 0.0 4.7e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM79146.1 - 0.00015 21.7 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIM79146.1 - 0.049 13.2 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-MYND PF01753.13 EIM79148.1 - 4.5e-06 26.4 16.3 4.5e-06 26.4 11.3 2.2 2 0 0 2 2 2 1 MYND finger Nop14 PF04147.7 EIM79148.1 - 1.4 6.7 14.5 2.8 5.7 10.1 1.4 1 0 0 1 1 1 0 Nop14-like family KilA-N PF04383.8 EIM79150.1 - 0.0013 18.3 0.2 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain dsrm PF00035.20 EIM79151.1 - 3.7e-08 33.8 0.2 6.5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EIM79151.1 - 9e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM79151.1 - 0.16 12.4 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain Mito_fiss_reg PF05308.6 EIM79151.1 - 0.22 10.8 7.7 0.3 10.4 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Helicase_C PF00271.26 EIM79153.1 - 0.00076 19.2 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIM79153.1 - 0.0075 15.1 0.0 0.0089 14.8 0.0 1.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.18 EIM79154.1 - 8.4e-37 126.5 0.3 9.8e-37 126.3 0.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EIM79154.1 - 1.5e-13 50.2 0.2 2.3e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 KRAB PF01352.22 EIM79154.1 - 0.026 13.9 0.6 0.059 12.8 0.1 1.9 2 0 0 2 2 2 0 KRAB box Ribosomal_S7 PF00177.16 EIM79157.1 - 2.2e-40 137.6 0.7 2.6e-40 137.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Amidohydro_4 PF13147.1 EIM79158.1 - 2.2e-19 70.5 10.7 1.1e-18 68.2 7.4 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM79158.1 - 2.1e-11 44.0 0.0 1.1e-07 31.8 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIM79158.1 - 3.1e-09 36.5 0.4 7.9e-08 32.0 0.1 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM79158.1 - 6.7e-07 28.8 1.9 2.3e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF4407 PF14362.1 EIM79159.1 - 0.078 11.9 4.9 0.12 11.2 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EIM79159.1 - 0.14 11.9 7.4 0.13 11.9 4.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Herpes_UL25 PF01499.11 EIM79159.1 - 0.16 10.2 10.0 0.3 9.3 6.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family IncA PF04156.9 EIM79159.1 - 1.9 8.0 7.8 3.8 7.0 5.4 1.6 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 EIM79159.1 - 3.6 6.5 4.9 5.4 6.0 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-ribbon_3 PF13248.1 EIM79160.1 - 0.18 11.0 1.2 0.36 10.1 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Gelsolin PF00626.17 EIM79161.1 - 0.012 15.3 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Gelsolin repeat Nse4_C PF08743.5 EIM79163.1 - 4.4e-21 74.7 0.9 7.6e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EIM79163.1 - 5e-16 58.2 1.6 5e-16 58.2 1.1 1.7 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE ARPC4 PF05856.7 EIM79164.1 - 1e-76 256.0 5.8 1.1e-76 255.9 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.23 EIM79165.1 - 1.2e-30 105.3 0.0 3.4e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HNF-1_N PF04814.8 EIM79165.1 - 3.2 7.8 7.4 0.89 9.6 0.1 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus adh_short PF00106.20 EIM79166.1 - 9.9e-28 97.1 2.2 1.3e-27 96.7 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79166.1 - 6.7e-27 94.8 1.2 8.2e-27 94.5 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79166.1 - 2.8e-12 46.6 4.1 2.4e-11 43.6 2.8 2.0 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EIM79166.1 - 0.0013 19.0 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RNA_pol_Rpb2_4 PF04566.8 EIM79167.1 - 0.047 13.5 0.2 0.16 11.8 0.2 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Calpain_inhib PF00748.14 EIM79167.1 - 0.48 10.7 6.2 0.15 12.4 1.6 1.9 2 0 0 2 2 2 0 Calpain inhibitor DUF1127 PF06568.6 EIM79167.1 - 3.1 7.3 7.6 0.38 10.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Acetyltransf_6 PF13480.1 EIM79167.1 - 9.2 6.2 12.0 4.3 7.2 1.8 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UDPGP PF01704.13 EIM79168.1 - 5.8e-181 601.5 1.0 6.7e-181 601.3 0.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF2470 PF10615.4 EIM79168.1 - 0.099 12.8 0.6 6.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2470) UDPGP PF01704.13 EIM79169.1 - 3.9e-180 598.8 2.0 4.5e-180 598.6 1.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase OTCace_N PF02729.16 EIM79170.1 - 1.9e-43 147.5 0.0 2.7e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EIM79170.1 - 1.4e-37 128.9 0.0 2.6e-37 128.1 0.0 1.4 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ribosomal_S8e PF01201.17 EIM79171.1 - 5.4e-50 168.9 1.0 7e-50 168.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF3837 PF12939.2 EIM79171.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) SET PF00856.23 EIM79172.1 - 1.7e-12 47.9 0.1 1.5e-11 44.8 0.1 2.1 1 1 0 1 1 1 1 SET domain zf-C2H2 PF00096.21 EIM79173.1 - 6.1e-13 48.2 7.4 5.3e-06 26.4 1.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM79173.1 - 2.5e-08 33.6 4.5 0.00041 20.4 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM79173.1 - 8.1e-08 32.1 8.9 6.7e-05 22.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM79173.1 - 0.00048 20.1 4.1 0.00099 19.1 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIM79173.1 - 0.0008 19.1 1.2 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2HC_2 PF13913.1 EIM79173.1 - 0.003 17.1 1.2 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EIM79173.1 - 0.037 13.9 1.8 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 EIM79173.1 - 0.05 13.7 0.8 0.099 12.7 0.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EIM79173.1 - 0.073 13.3 3.2 0.11 12.7 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EIM79173.1 - 0.28 10.8 1.8 0.55 9.9 1.3 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF4278 PF14105.1 EIM79173.1 - 0.6 10.1 3.2 2.8 7.9 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4278) BolA PF01722.13 EIM79174.1 - 3.1e-28 97.5 0.2 4e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein DNA_ligase_A_M PF01068.16 EIM79176.1 - 4.6e-41 140.4 0.0 3.5e-38 131.0 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIM79176.1 - 3.9e-38 131.0 0.0 6.9e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIM79176.1 - 2.1e-17 63.3 0.0 6.6e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region zf-C2H2 PF00096.21 EIM79177.1 - 1.8e-10 40.4 8.1 8.2e-05 22.7 0.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM79177.1 - 2.2e-10 40.1 6.2 0.00014 21.9 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM79177.1 - 5.1e-09 35.9 7.0 2.6e-07 30.5 0.6 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM79177.1 - 0.0001 22.3 4.1 0.0095 16.0 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM79177.1 - 0.00032 20.7 2.1 0.3 11.3 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIM79177.1 - 0.089 13.0 2.7 0.33 11.2 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain BolA PF01722.13 EIM79177.1 - 0.14 12.1 0.1 13 5.7 0.0 2.0 2 0 0 2 2 2 0 BolA-like protein Acetyltransf_1 PF00583.19 EIM79178.1 - 5.5e-13 48.7 0.0 8.5e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM79178.1 - 9.7e-10 38.4 0.3 2.8e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM79178.1 - 4.8e-06 26.6 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM79178.1 - 1.9e-05 24.5 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM79178.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIM79178.1 - 0.0019 18.4 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM79178.1 - 0.056 13.1 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein SRP-alpha_N PF04086.8 EIM79179.1 - 0.014 14.8 0.4 0.023 14.1 0.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 EIM79180.1 - 2.8e-61 206.9 0.0 3.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM79180.1 - 3e-37 128.0 0.0 3.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM79180.1 - 3e-06 26.4 0.0 7.7e-06 25.0 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EIM79180.1 - 0.063 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EIM79180.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RB_A PF01858.12 EIM79180.1 - 0.14 11.8 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain Zn_clus PF00172.13 EIM79181.1 - 6.4e-08 32.3 9.7 1.1e-07 31.6 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.16 EIM79182.1 - 2.5e-62 210.5 0.1 2.7e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EIM79182.1 - 7.9e-05 22.4 0.5 0.00042 20.0 0.3 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) RuvA_C PF07499.8 EIM79182.1 - 0.046 13.8 0.2 0.22 11.7 0.1 2.2 3 0 0 3 3 3 0 RuvA, C-terminal domain Choline_transpo PF04515.7 EIM79183.1 - 2.9e-87 292.5 12.8 2.9e-87 292.5 8.9 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter TMEMspv1-c74-12 PF11044.3 EIM79183.1 - 7.6 6.1 12.0 9.2 5.9 2.5 2.8 1 1 1 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Acyltransferase PF01553.16 EIM79184.1 - 4.9e-18 64.8 0.0 8.5e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NUC173 PF08161.7 EIM79185.1 - 1.8e-41 141.6 0.1 1.1e-40 139.1 0.0 2.4 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 EIM79185.1 - 2.7e-05 23.8 0.3 1.6 9.0 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.2 EIM79185.1 - 0.058 13.2 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3554 PF12074.3 EIM79185.1 - 0.16 11.3 3.1 0.62 9.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3554) PAC2 PF09754.4 EIM79186.1 - 9.2e-16 58.3 0.0 3.1e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 PAC2 family XPG_N PF00752.12 EIM79187.1 - 3.6e-16 59.2 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIM79187.1 - 8.9e-15 54.5 0.1 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region Hus1 PF04005.7 EIM79188.1 - 0.0043 16.0 0.3 0.0072 15.3 0.2 1.3 1 0 0 1 1 1 1 Hus1-like protein TRAP_alpha PF03896.11 EIM79188.1 - 0.15 10.9 1.7 0.3 10.0 1.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Gluconate_2-dh3 PF13618.1 EIM79188.1 - 0.21 11.7 0.9 25 5.0 0.0 3.2 3 0 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 DUF123 PF01986.11 EIM79189.1 - 0.023 14.8 0.0 0.09 12.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF123 zf-MYND PF01753.13 EIM79190.1 - 3.4e-09 36.4 7.7 9.9e-09 34.9 5.4 1.9 1 0 0 1 1 1 1 MYND finger DUF4121 PF13497.1 EIM79190.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Acyl_transf_1 PF00698.16 EIM79193.1 - 0.051 12.9 0.1 0.051 12.9 0.0 1.0 1 0 0 1 1 1 0 Acyl transferase domain DUF4113 PF13438.1 EIM79193.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Ion_trans PF00520.26 EIM79195.1 - 1.9e-27 95.8 25.5 5.7e-18 64.8 3.1 2.9 2 1 0 2 2 2 2 Ion transport protein Sec34 PF04136.10 EIM79198.1 - 5.5e-30 104.1 0.0 1.2e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family DUF87 PF01935.12 EIM79200.1 - 0.075 12.8 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1752 PF08550.5 EIM79201.1 - 1.7e-13 49.8 0.7 2.1e-13 49.5 0.5 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3141 PF11339.3 EIM79203.1 - 0.055 11.7 0.0 0.077 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Helitron_like_N PF14214.1 EIM79207.1 - 3.9e-09 36.4 0.0 5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIM79210.1 - 2.6e-07 29.9 0.0 8.6e-05 21.6 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase APH PF01636.18 EIM79213.1 - 0.062 13.0 0.1 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PHD PF00628.24 EIM79214.1 - 2.1e-07 30.5 11.7 3.9e-07 29.6 8.1 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EIM79214.1 - 0.0063 16.8 0.0 0.044 14.0 0.0 2.4 2 0 0 2 2 2 1 SET domain NDUFA12 PF05071.11 EIM79214.1 - 0.021 15.2 0.5 0.08 13.4 0.0 2.2 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 PHD_2 PF13831.1 EIM79214.1 - 1.1 8.5 8.3 2.1 7.7 5.8 1.4 1 0 0 1 1 1 0 PHD-finger APH PF01636.18 EIM79217.1 - 1.1e-12 48.2 0.0 2.7e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIM79217.1 - 0.026 13.1 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MMR_HSR1 PF01926.18 EIM79219.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM79219.1 - 6.9e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIM79219.1 - 0.00015 22.2 0.1 0.0019 18.6 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 EIM79219.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 EIM79219.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EIM79219.1 - 0.0067 16.2 0.1 0.053 13.3 0.1 2.2 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EIM79219.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_10 PF12846.2 EIM79219.1 - 0.011 15.1 0.3 0.39 10.1 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_16 PF13191.1 EIM79219.1 - 0.018 15.0 0.3 0.089 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.22 EIM79219.1 - 0.045 13.1 0.0 0.52 9.7 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EIM79219.1 - 0.051 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EIM79219.1 - 0.082 12.1 0.4 0.37 10.0 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 EIM79219.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EIM79219.1 - 0.096 13.5 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Herpes_gE PF02480.11 EIM79220.1 - 0.0078 14.5 0.0 0.013 13.7 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EIM79220.1 - 0.095 12.3 0.4 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain TauD PF02668.11 EIM79223.1 - 6.8e-51 173.4 0.3 8.3e-51 173.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactonase PF10282.4 EIM79226.1 - 1.1e-32 113.4 0.3 1.6e-32 112.9 0.1 1.2 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cutinase PF01083.17 EIM79227.1 - 4.2e-47 160.1 1.8 4.8e-47 159.9 1.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EIM79227.1 - 0.0027 17.1 0.1 0.004 16.5 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain SNF2_N PF00176.18 EIM79228.1 - 7.2e-40 136.6 0.1 2.6e-35 121.6 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM79228.1 - 4.4e-10 39.2 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM79228.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM79228.1 - 6.4e-06 26.1 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2235 PF09994.4 EIM79229.1 - 2.2e-38 132.2 0.0 4.5e-37 127.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) H_lectin PF09458.5 EIM79230.1 - 2.2e-33 113.7 0.0 2.2e-13 49.6 0.0 3.1 3 0 0 3 3 3 3 H-type lectin domain WD40 PF00400.27 EIM79232.1 - 7e-59 193.7 27.8 9.2e-13 47.5 0.3 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM79232.1 - 2.3e-08 33.2 0.7 0.32 9.6 0.0 4.1 1 1 3 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 EIM79232.1 - 2.5e-06 25.9 4.0 0.42 8.6 0.0 4.1 2 2 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EIM79232.1 - 3.1e-05 23.6 0.1 1.7 8.4 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EIM79232.1 - 0.00015 21.3 0.5 1.8 7.9 0.2 3.3 1 1 2 3 3 3 3 PQQ-like domain PD40 PF07676.7 EIM79232.1 - 0.0027 17.3 0.0 77 3.1 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF4072 PF13284.1 EIM79232.1 - 0.0036 17.4 0.1 5.5 7.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4072) PQQ_3 PF13570.1 EIM79232.1 - 0.0044 17.2 0.1 2.3 8.6 0.0 3.3 2 2 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 EIM79232.1 - 0.0044 15.3 0.2 0.3 9.3 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Peptidase_S9_N PF02897.10 EIM79232.1 - 0.0074 14.9 0.2 2 6.9 0.1 3.4 2 2 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.1 EIM79232.1 - 0.02 14.0 0.7 11 5.0 0.0 3.6 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SAF_2 PF13144.1 EIM79232.1 - 0.071 12.5 0.0 9.1 5.7 0.0 2.2 2 0 0 2 2 2 0 SAF-like DUF3312 PF11768.3 EIM79232.1 - 0.12 10.5 0.8 2.8 6.0 0.1 2.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3312) Amidohydro_4 PF13147.1 EIM79233.1 - 3.5e-13 50.2 4.6 1.4e-12 48.2 2.0 2.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM79233.1 - 8.8e-10 38.7 1.5 7.2e-07 29.1 0.0 2.9 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIM79233.1 - 1.3e-08 34.5 0.3 4.4e-08 32.8 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM79233.1 - 2.2e-06 27.1 0.5 0.00033 20.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family DUF4470 PF14737.1 EIM79235.1 - 3.3e-20 71.7 0.0 8.1e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM79235.1 - 1.2e-06 28.2 14.4 2e-06 27.5 10.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM79235.1 - 0.19 11.5 6.0 0.46 10.3 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EIM79236.1 - 6e-07 29.2 15.7 1.3e-06 28.1 10.9 1.6 1 0 0 1 1 1 1 MYND finger Pilus_CpaD PF09476.5 EIM79236.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2267 PF10025.4 EIM79236.1 - 0.037 14.0 0.3 0.21 11.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Pkinase PF00069.20 EIM79236.1 - 0.11 11.6 0.1 0.81 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.9 EIM79237.1 - 0.019 14.0 0.8 0.034 13.1 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3638 PF12340.3 EIM79238.1 - 7.9e-77 257.3 1.0 1.4e-76 256.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIM79238.1 - 4.4e-16 57.7 0.1 1.1e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Sod_Fe_C PF02777.13 EIM79240.1 - 3e-38 129.8 0.1 5.3e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIM79240.1 - 5.3e-32 109.9 5.2 5.5e-32 109.8 2.7 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_10 PF05971.7 EIM79242.1 - 2.6e-56 190.9 0.0 3.7e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EIM79242.1 - 1.8e-06 27.9 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM79242.1 - 5.4e-05 22.6 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIM79242.1 - 0.0021 18.5 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIM79242.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIM79242.1 - 0.012 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIM79242.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EIM79242.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF633 PF04816.7 EIM79242.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Abhydrolase_6 PF12697.2 EIM79243.1 - 1.6e-33 116.4 0.0 2.6e-33 115.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM79243.1 - 4.9e-24 85.1 0.0 3.6e-23 82.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM79243.1 - 2.1e-12 46.9 0.0 5.8e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EIM79243.1 - 3e-09 35.7 0.0 4.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EIM79243.1 - 0.0079 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EIM79243.1 - 0.085 12.7 0.1 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase F-box-like PF12937.2 EIM79244.1 - 1.4e-05 24.7 0.5 6.4e-05 22.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM79245.1 - 7.5e-05 22.3 0.2 0.0002 21.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like UCR_hinge PF02320.11 EIM79246.1 - 1.1e-18 66.9 2.4 2.1e-18 66.0 1.7 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EIM79246.1 - 0.061 12.9 5.7 0.068 12.7 3.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GOLD_2 PF13897.1 EIM79246.1 - 0.092 12.9 1.4 0.13 12.4 1.0 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking eIF-3c_N PF05470.7 EIM79246.1 - 0.42 8.6 3.9 0.45 8.5 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1510 PF07423.6 EIM79246.1 - 0.53 9.6 6.5 0.55 9.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EIM79246.1 - 0.55 8.0 8.2 0.56 8.0 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 EIM79246.1 - 1.4 7.6 8.3 1.6 7.4 5.8 1.1 1 0 0 1 1 1 0 Paf1 Na_trans_assoc PF06512.8 EIM79246.1 - 1.5 8.7 8.9 1.8 8.4 6.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated SspB PF04386.8 EIM79246.1 - 3.4 7.2 5.2 4.5 6.8 3.6 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DDRGK PF09756.4 EIM79246.1 - 3.5 7.0 10.3 4 6.7 7.1 1.1 1 0 0 1 1 1 0 DDRGK domain Trypan_PARP PF05887.6 EIM79246.1 - 3.6 7.4 17.3 4.9 6.9 12.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OAD_gamma PF04277.8 EIM79246.1 - 5.9 7.3 5.1 13 6.2 3.5 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CobT PF06213.7 EIM79246.1 - 6.4 5.8 11.1 8.1 5.4 7.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EIM79246.1 - 7.9 4.8 12.8 8.2 4.7 8.9 1.0 1 0 0 1 1 1 0 Daxx Family DUF3995 PF13160.1 EIM79247.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) PsaL PF02605.10 EIM79247.1 - 0.11 12.0 0.8 0.16 11.4 0.5 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI BBE PF08031.7 EIM79248.1 - 8.7e-05 22.3 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EIM79248.1 - 0.0016 17.9 0.0 0.0048 16.3 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain O-FucT PF10250.4 EIM79249.1 - 2.4e-07 30.1 0.0 0.00041 19.5 0.0 3.1 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase CAS_CSE1 PF03378.10 EIM79251.1 - 3.6e-112 374.8 0.0 6.1e-112 374.0 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EIM79251.1 - 1.5e-81 273.8 0.0 2.3e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EIM79251.1 - 3.1e-13 49.4 0.1 4.5e-11 42.5 0.0 3.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EIM79251.1 - 0.0012 18.7 1.7 0.02 14.8 0.0 3.5 3 1 0 4 4 4 1 Exportin 1-like protein Cullin_binding PF03556.10 EIM79251.1 - 0.059 13.5 0.3 4 7.6 0.0 2.8 3 0 0 3 3 3 0 Cullin binding HEAT_2 PF13646.1 EIM79251.1 - 0.17 12.1 2.0 8.7 6.7 0.0 3.7 2 1 0 3 3 3 0 HEAT repeats DUF3638 PF12340.3 EIM79254.1 - 1e-77 260.2 1.6 1.6e-76 256.2 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIM79254.1 - 9.7e-16 56.6 1.7 1.3e-15 56.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) DUF2992 PF11208.3 EIM79254.1 - 0.069 13.0 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) HHA PF05321.6 EIM79255.1 - 0.14 12.3 0.3 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Haemolysin expression modulating protein MFS_1 PF07690.11 EIM79256.1 - 6.1e-22 77.8 55.5 1.7e-20 73.0 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIM79256.1 - 7.3 6.6 12.0 0.67 10.0 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) F-box-like PF12937.2 EIM79257.1 - 5.2e-05 22.8 0.1 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like NAD_binding_4 PF07993.7 EIM79259.1 - 4.4e-09 35.6 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein p450 PF00067.17 EIM79260.1 - 1.7e-59 201.5 0.0 2.6e-59 200.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DUF3719 PF12516.3 EIM79260.1 - 0.085 12.4 0.2 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Methyltransf_23 PF13489.1 EIM79261.1 - 0.00027 20.7 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM79261.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM79261.1 - 0.097 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIM79261.1 - 0.14 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EIM79262.1 - 9.9e-10 38.5 0.1 1.1e-09 38.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM79262.1 - 1.6e-05 24.6 0.1 1.9e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM79262.1 - 7.9e-05 22.7 0.1 9.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EIM79262.1 - 0.00093 19.2 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIM79262.1 - 0.003 16.6 0.1 0.0034 16.4 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIM79262.1 - 0.003 17.0 0.1 0.0035 16.8 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM79262.1 - 0.012 14.8 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 0 NmrA-like family SBP_bac_3 PF00497.15 EIM79262.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 adh_short_C2 PF13561.1 EIM79262.1 - 0.075 12.7 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Nop14 PF04147.7 EIM79263.1 - 7.3 4.3 12.0 0.042 11.7 2.1 1.6 2 0 0 2 2 2 0 Nop14-like family TPR_12 PF13424.1 EIM79264.1 - 0.012 15.5 0.0 0.097 12.6 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Trp_halogenase PF04820.9 EIM79267.1 - 2.3e-29 102.3 0.3 8.5e-16 57.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EIM79267.1 - 7.5e-11 41.6 0.5 1.1e-09 37.8 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM79267.1 - 1.3e-06 27.5 0.0 7.2e-05 21.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIM79267.1 - 2.7e-06 26.7 0.1 1.5e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM79267.1 - 4.8e-06 26.5 0.1 5.1e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIM79267.1 - 9.1e-05 21.4 0.1 0.00015 20.8 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EIM79267.1 - 9.5e-05 22.3 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79267.1 - 0.00022 19.8 0.0 0.00035 19.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIM79267.1 - 0.001 18.0 0.0 0.0021 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM79267.1 - 0.0014 17.8 0.0 0.0045 16.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIM79267.1 - 0.0086 16.4 0.1 0.095 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EIM79267.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EIM79267.1 - 0.035 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIM79267.1 - 0.092 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EIM79267.1 - 0.12 11.7 0.1 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EIM79267.1 - 0.17 11.6 0.0 0.76 9.4 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_2 PF00891.13 EIM79268.1 - 1.5e-24 86.5 0.0 6.1e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM79268.1 - 2.7e-05 24.6 0.0 6.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM79268.1 - 0.00027 20.5 0.0 0.00057 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM79268.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EIM79268.1 - 0.00095 18.9 0.0 0.003 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIM79268.1 - 0.005 16.3 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EIM79268.1 - 0.013 15.9 0.0 0.058 13.8 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain DOT1 PF08123.8 EIM79268.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EIM79268.1 - 0.074 13.5 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIM79268.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Transposase_21 PF02992.9 EIM79269.1 - 1.4e-11 43.9 0.0 3.9e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 2OG-FeII_Oxy_3 PF13640.1 EIM79270.1 - 0.095 13.2 0.1 0.4 11.2 0.1 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HSP70 PF00012.15 EIM79271.1 - 1.1e-56 191.9 0.2 9e-55 185.7 0.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EIM79271.1 - 5e-08 31.9 1.1 7e-08 31.4 0.8 1.1 1 0 0 1 1 1 1 MreB/Mbl protein LUC7 PF03194.10 EIM79271.1 - 0.11 11.9 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Pap_E4 PF02711.9 EIM79272.1 - 2.2 9.1 5.2 2.3 9.1 2.2 2.1 2 0 0 2 2 2 0 E4 protein p450 PF00067.17 EIM79276.1 - 9.4e-62 209.0 0.0 4.6e-42 144.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DPBB_1 PF03330.13 EIM79277.1 - 2e-06 27.7 0.0 4.5e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cys_rich_CPXG PF14255.1 EIM79277.1 - 0.091 12.5 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG Barwin PF00967.12 EIM79277.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Barwin family OTT_1508_deam PF14441.1 EIM79278.1 - 0.033 14.0 0.0 0.097 12.4 0.0 1.6 1 1 0 1 1 1 0 OTT_1508-like deaminase Ecl1 PF12855.2 EIM79279.1 - 0.086 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Life-span regulatory factor Zip PF02535.17 EIM79279.1 - 9 5.1 10.2 16 4.3 7.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.7 EIM79280.1 - 0.38 8.4 1.3 0.48 8.1 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4293 PF14126.1 EIM79281.1 - 0.002 18.0 0.2 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) Alpha_GJ PF03229.8 EIM79281.1 - 0.0075 16.6 1.9 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 Alphavirus glycoprotein J MGC-24 PF05283.6 EIM79281.1 - 0.021 14.6 0.9 0.021 14.6 0.6 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) stn_TNFRSF12A PF12191.3 EIM79281.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain HIF-1a_CTAD PF08778.5 EIM79281.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Syndecan PF01034.15 EIM79281.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain p450 PF00067.17 EIM79282.1 - 3.2e-57 194.0 0.0 5.5e-51 173.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_28 PF00295.12 EIM79283.1 - 5.8e-26 91.2 4.3 8.2e-26 90.7 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_M28 PF04389.12 EIM79284.1 - 9.8e-31 106.8 0.2 2.2e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIM79284.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Polysacc_lyase PF14099.1 EIM79285.1 - 0.039 13.5 1.1 1.2 8.7 0.2 2.0 1 1 1 2 2 2 0 Polysaccharide lyase GLTP PF08718.6 EIM79286.1 - 8.6e-34 116.7 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fungal_trans PF04082.13 EIM79288.1 - 2.2e-22 79.1 0.0 4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM79288.1 - 1.8e-05 24.5 14.5 3.2e-05 23.7 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EIM79290.1 - 3.8e-24 85.4 0.0 9.5e-24 84.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM79290.1 - 0.00012 21.9 0.1 0.00034 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM79290.1 - 0.0019 17.1 0.6 0.0037 16.2 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM79290.1 - 0.013 14.4 0.1 0.057 12.3 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein SE PF08491.5 EIM79290.1 - 0.015 14.1 0.0 0.1 11.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EIM79290.1 - 0.018 14.1 0.1 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIM79290.1 - 0.034 13.9 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIM79290.1 - 0.18 10.3 0.7 10 4.5 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase B12-binding PF02310.14 EIM79291.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain SBP_bac_6 PF13343.1 EIM79292.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein UPF0167 PF03691.9 EIM79294.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) DUF2376 PF09550.5 EIM79295.1 - 0.026 14.6 0.1 0.064 13.4 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) Zn_clus PF00172.13 EIM79297.1 - 0.15 12.0 9.7 0.35 10.8 6.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EIM79298.1 - 3.4e-94 305.7 22.3 6.5e-14 51.1 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EIM79298.1 - 4e-11 43.0 0.0 3.2e-06 26.9 0.0 2.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIM79298.1 - 4.2e-11 41.7 2.7 0.34 8.9 0.1 6.4 3 2 4 7 7 7 5 Nucleoporin Nup120/160 PD40 PF07676.7 EIM79298.1 - 1.2e-07 31.2 5.2 1.3 8.7 0.0 6.4 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIM79298.1 - 9.8e-06 24.0 0.1 0.00082 17.7 0.0 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 EIM79298.1 - 0.00084 18.5 1.7 4.1 6.4 0.0 5.2 1 1 5 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EIM79298.1 - 0.0019 17.6 0.9 3.5 6.9 0.0 3.0 1 1 2 4 4 4 2 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EIM79298.1 - 0.0023 16.7 0.0 18 3.8 0.0 4.5 2 1 3 5 5 5 0 Nup133 N terminal like PQQ_2 PF13360.1 EIM79298.1 - 0.013 15.0 0.1 0.24 10.8 0.0 3.1 1 1 1 2 2 2 0 PQQ-like domain SdiA-regulated PF06977.6 EIM79298.1 - 0.03 13.2 0.0 0.23 10.3 0.0 2.2 2 1 0 2 2 2 0 SdiA-regulated PQQ PF01011.16 EIM79298.1 - 0.13 11.8 0.2 14 5.3 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.1 EIM79298.1 - 1 9.7 5.3 5.9 7.2 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 EIM79298.1 - 3.4 7.0 15.8 18 4.7 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF2235 PF09994.4 EIM79299.1 - 2e-52 178.2 0.2 2.7e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-MYND PF01753.13 EIM79300.1 - 2.7e-09 36.7 10.5 6.5e-09 35.5 7.3 1.7 1 0 0 1 1 1 1 MYND finger KAR9 PF08580.5 EIM79301.1 - 2.3 6.3 15.6 2.9 6.0 10.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DnaJ_CXXCXGXG PF00684.14 EIM79302.1 - 0.0039 17.2 4.8 0.26 11.3 0.2 2.5 2 0 0 2 2 2 2 DnaJ central domain SQS_PSY PF00494.14 EIM79305.1 - 5.5e-40 137.3 0.0 7.5e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3789 PF12664.2 EIM79305.1 - 0.09 12.1 3.4 0.19 11.0 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) VQ PF05678.9 EIM79305.1 - 0.099 11.7 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 VQ motif VEFS-Box PF09733.4 EIM79309.1 - 0.04 13.5 0.3 0.067 12.8 0.2 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein RCC1 PF00415.13 EIM79311.1 - 2.4e-35 120.4 17.1 1.5e-13 50.7 0.0 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM79311.1 - 3.3e-17 61.6 23.3 7.1e-08 31.8 0.3 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EIM79311.1 - 1.5e-08 34.1 5.8 1.5e-08 34.1 4.0 2.5 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 EIM79311.1 - 0.002 17.7 2.3 0.002 17.7 1.6 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 Reg_prop PF07494.6 EIM79311.1 - 0.066 13.2 0.2 6.3 7.1 0.0 3.8 4 0 0 4 4 4 0 Two component regulator propeller DAO PF01266.19 EIM79312.1 - 7.2e-39 133.6 0.1 8.7e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM79312.1 - 1.9e-05 24.5 0.6 5.7e-05 23.0 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM79312.1 - 0.0068 16.1 0.0 0.046 13.4 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIM79312.1 - 0.041 13.9 0.0 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM79312.1 - 0.07 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM79312.1 - 0.15 11.1 0.2 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family SIS PF01380.17 EIM79313.1 - 0.12 11.9 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 SIS domain adh_short PF00106.20 EIM79315.1 - 6.1e-21 75.0 0.2 1.1e-20 74.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79315.1 - 9e-07 28.9 1.0 6.1e-06 26.1 0.7 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79315.1 - 8.5e-06 25.5 0.1 1.5e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 EIM79315.1 - 0.0023 18.3 0.7 0.004 17.5 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EIM79315.1 - 0.0054 16.1 0.1 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EIM79315.1 - 0.012 15.6 0.1 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 EIM79315.1 - 0.042 13.6 0.1 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FA_hydroxylase PF04116.8 EIM79318.1 - 3.9e-08 33.6 22.3 3.9e-08 33.6 15.5 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EIM79319.1 - 3.8e-10 39.9 0.8 2.1e-09 37.5 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_15 PF09445.5 EIM79320.1 - 6.2e-39 133.1 0.0 6.1e-37 126.6 0.0 2.3 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EIM79320.1 - 3.3e-09 37.3 0.0 5.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM79320.1 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM79320.1 - 3.3e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIM79320.1 - 3.5e-05 23.4 0.0 5.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EIM79320.1 - 0.00033 20.9 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIM79320.1 - 0.00036 20.1 0.1 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EIM79320.1 - 0.0054 16.1 0.1 0.74 9.1 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EIM79320.1 - 0.0058 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EIM79320.1 - 0.016 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase XFP_N PF09364.5 EIM79320.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain DUF1180 PF06679.7 EIM79320.1 - 0.3 10.9 1.6 0.55 10.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cupin_2 PF07883.6 EIM79325.1 - 1.3e-06 27.7 0.2 2.1e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain CENP-T PF15511.1 EIM79328.1 - 0.00056 19.2 10.6 0.00066 19.0 7.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T DUF4492 PF14899.1 EIM79329.1 - 0.083 12.4 0.5 3.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) DUF3583 PF12126.3 EIM79329.1 - 0.098 11.7 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) bZIP_1 PF00170.16 EIM79330.1 - 0.081 12.8 10.5 0.17 11.8 0.5 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF4200 PF13863.1 EIM79330.1 - 1.9 8.4 12.3 1.7 8.6 7.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EIM79330.1 - 2.4 8.2 8.8 43 4.1 5.9 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RCC1 PF00415.13 EIM79331.1 - 1.7e-17 63.3 18.8 7.5e-06 26.0 0.0 5.5 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EIM79331.1 - 2.1e-11 44.0 0.0 3e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM79331.1 - 5.7e-11 42.6 2.1 1.6e-09 38.0 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM79331.1 - 1.5e-09 37.7 1.6 8.5e-05 22.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM79331.1 - 9.8e-08 31.5 0.3 0.011 15.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EIM79331.1 - 1.2e-07 31.2 0.8 0.0044 16.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat BTB PF00651.26 EIM79331.1 - 4.2e-07 29.9 0.0 0.0045 16.9 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EIM79331.1 - 4.5e-07 29.3 0.1 4.5e-07 29.3 0.1 4.0 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat DUF3342 PF11822.3 EIM79331.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) MlrC_C PF07171.7 EIM79331.1 - 0.063 12.8 1.8 0.12 11.9 1.2 1.4 1 0 0 1 1 1 0 MlrC C-terminus Lipase_3 PF01764.20 EIM79332.1 - 1.2e-34 118.8 0.0 1.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) MNSV_P7B PF06692.6 EIM79332.1 - 0.0084 15.8 0.2 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 Melon necrotic spot virus P7B protein DUF2974 PF11187.3 EIM79332.1 - 0.032 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 EIM79332.1 - 0.099 12.0 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1900 PF08954.6 EIM79333.1 - 1.1e-44 151.2 0.0 4.1e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EIM79333.1 - 2.8e-28 97.3 0.1 5e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EIM79333.1 - 1.1e-22 79.0 7.0 1.9e-08 33.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF605 PF04652.11 EIM79333.1 - 8.1 5.7 12.2 11 5.2 8.5 1.1 1 0 0 1 1 1 0 Vta1 like FAD_binding_3 PF01494.14 EIM79334.1 - 1.3e-19 70.5 0.0 2.4e-19 69.6 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM79334.1 - 1.1e-08 34.3 4.1 2.8e-07 29.7 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM79334.1 - 1.2e-08 34.8 0.3 2.9e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM79334.1 - 1.2e-06 27.7 0.1 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM79334.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM79334.1 - 0.00011 21.4 0.0 0.037 13.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIM79334.1 - 0.0019 16.7 0.1 0.0028 16.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EIM79334.1 - 0.0063 15.1 0.0 0.91 8.0 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIM79334.1 - 0.0066 15.4 0.0 0.22 10.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIM79334.1 - 0.011 16.1 0.3 0.032 14.6 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM79334.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIM79334.1 - 0.026 14.3 0.3 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EIM79334.1 - 0.037 12.8 0.3 0.069 12.0 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EIM79334.1 - 0.15 11.2 0.5 2 7.5 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase GCV_T PF01571.16 EIM79335.1 - 2.3e-65 219.9 0.1 3e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIM79335.1 - 2.6e-24 85.0 0.2 5.6e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PRAP PF15314.1 EIM79337.1 - 0.11 12.8 0.3 0.11 12.8 0.2 2.0 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine AAA_2 PF07724.9 EIM79339.1 - 5.1e-47 159.9 0.0 7.2e-44 149.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIM79339.1 - 4e-21 75.5 0.1 3.4e-11 43.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIM79339.1 - 1.6e-20 72.7 2.6 4.9e-20 71.2 0.1 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIM79339.1 - 2.4e-17 62.9 0.0 9.4e-11 41.5 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM79339.1 - 2.5e-13 50.4 3.9 2.1e-05 24.6 0.0 4.1 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EIM79339.1 - 1.3e-10 41.5 0.0 0.0011 19.0 0.0 3.5 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIM79339.1 - 3.6e-08 33.0 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIM79339.1 - 1.4e-07 31.8 0.0 0.034 14.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIM79339.1 - 2.1e-07 31.7 6.3 0.005 17.6 0.0 4.1 5 1 0 5 5 3 2 AAA domain Mg_chelatase PF01078.16 EIM79339.1 - 2.6e-07 29.9 0.0 0.097 11.8 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIM79339.1 - 3.6e-07 30.1 0.0 0.0087 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIM79339.1 - 6.6e-07 28.9 0.1 0.019 14.3 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_23 PF13476.1 EIM79339.1 - 2.2e-06 28.1 5.7 0.05 13.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EIM79339.1 - 5.2e-06 26.3 7.5 0.0089 15.7 0.0 4.4 3 2 1 4 4 4 2 Archaeal ATPase ABC_tran PF00005.22 EIM79339.1 - 9.1e-06 26.0 1.1 0.076 13.3 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 EIM79339.1 - 2.1e-05 24.5 0.1 0.28 11.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EIM79339.1 - 0.0001 22.0 0.0 0.056 13.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EIM79339.1 - 0.00014 21.9 0.0 0.7 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EIM79339.1 - 0.00016 20.7 0.5 0.44 9.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 EIM79339.1 - 0.00019 21.1 0.0 0.079 12.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIM79339.1 - 0.00041 19.3 0.0 0.023 13.6 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EIM79339.1 - 0.00075 18.9 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.1 EIM79339.1 - 0.00075 19.1 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIM79339.1 - 0.0009 18.4 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIM79339.1 - 0.0011 18.4 1.7 0.65 9.3 0.0 3.4 3 2 0 3 3 2 1 AAA domain NACHT PF05729.7 EIM79339.1 - 0.0012 18.5 0.0 0.43 10.2 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EIM79339.1 - 0.0018 17.4 0.0 0.19 10.8 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EIM79339.1 - 0.0038 16.9 0.3 2.9 7.5 0.0 3.7 4 0 0 4 4 4 1 NTPase MMR_HSR1 PF01926.18 EIM79339.1 - 0.0053 16.7 0.0 1.5 8.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EIM79339.1 - 0.0089 15.9 0.0 5.8 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIM79339.1 - 0.0097 15.3 0.0 0.98 8.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EIM79339.1 - 0.012 15.1 0.0 0.49 9.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.10 EIM79339.1 - 0.013 15.3 1.3 12 5.6 0.0 3.7 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit Miro PF08477.8 EIM79339.1 - 0.013 15.9 0.0 0.36 11.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Bac_DnaA PF00308.13 EIM79339.1 - 0.016 14.8 0.1 4.8 6.7 0.0 2.7 3 0 0 3 3 2 0 Bacterial dnaA protein DNA_pol3_delta2 PF13177.1 EIM79339.1 - 0.022 14.4 0.0 0.15 11.7 0.0 2.3 2 1 0 2 2 1 0 DNA polymerase III, delta subunit RdRP_4 PF02123.11 EIM79339.1 - 0.028 13.1 0.1 0.96 8.0 0.0 2.5 3 0 0 3 3 3 0 Viral RNA-directed RNA-polymerase AAA_3 PF07726.6 EIM79339.1 - 0.033 13.7 0.1 17 5.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF342 PF03961.8 EIM79339.1 - 0.04 12.3 2.3 0.079 11.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_21 PF13304.1 EIM79339.1 - 0.041 13.8 1.7 3.1 7.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 EIM79339.1 - 0.066 12.7 0.0 0.96 8.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bacillus_HBL PF05791.6 EIM79339.1 - 0.17 11.1 4.0 0.43 9.9 2.8 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 EIM79339.1 - 0.18 11.6 18.4 0.074 12.9 10.6 2.0 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EIM79339.1 - 0.21 10.6 9.6 0.33 9.9 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_11 PF13086.1 EIM79339.1 - 0.22 11.0 2.6 9.4 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain IncA PF04156.9 EIM79339.1 - 7.1 6.1 14.0 14 5.2 9.7 1.4 1 0 0 1 1 1 0 IncA protein SE PF08491.5 EIM79340.1 - 1.9e-93 312.2 0.0 2.5e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EIM79340.1 - 3.6e-07 29.5 0.0 0.0066 15.5 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM79340.1 - 4e-06 25.9 0.0 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM79340.1 - 0.0021 17.0 0.1 0.02 13.8 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM79340.1 - 0.014 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM79340.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM79340.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM79340.1 - 0.13 10.8 0.0 3.8 6.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EIM79340.1 - 0.15 10.8 3.5 2.7 6.7 2.4 2.2 2 0 0 2 2 2 0 FAD binding domain DnaJ PF00226.26 EIM79342.1 - 7.9e-12 44.7 0.1 7.9e-12 44.7 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain NAD_binding_10 PF13460.1 EIM79343.1 - 1.4e-10 41.5 0.0 3.4e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM79343.1 - 0.0017 17.8 0.1 0.0041 16.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM79343.1 - 0.0044 15.9 0.2 0.9 8.4 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 EIM79343.1 - 0.018 15.3 0.1 0.032 14.5 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EIM79343.1 - 0.032 14.1 0.1 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EIM79343.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EIM79344.1 - 1.4e-10 41.4 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIM79344.1 - 0.00017 21.8 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIM79344.1 - 0.0032 16.9 0.0 0.0061 16.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM79344.1 - 0.059 12.6 0.2 0.22 10.7 0.1 1.9 1 1 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EIM79344.1 - 0.061 13.2 0.1 0.8 9.6 0.1 2.1 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EIM79344.1 - 0.076 11.9 0.2 2.8 6.7 0.1 2.4 1 1 1 2 2 2 0 Male sterility protein DapB_N PF01113.15 EIM79344.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_N PF03721.9 EIM79344.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NADH_4Fe-4S PF10589.4 EIM79345.1 - 0.064 12.4 0.1 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TPR_MLP1_2 PF07926.7 EIM79346.1 - 0.00069 19.3 2.6 0.00069 19.3 1.8 3.1 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Sec8_exocyst PF04048.9 EIM79346.1 - 0.044 13.4 0.5 0.09 12.4 0.3 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EIM79346.1 - 6.8 6.2 10.7 5.9 6.4 6.3 1.5 1 1 0 1 1 1 0 IncA protein zf-CCHC PF00098.18 EIM79348.1 - 3.2e-05 23.6 2.1 6.9e-05 22.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIM79348.1 - 0.00024 20.7 0.4 0.00058 19.5 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Nsp1_C PF05064.8 EIM79348.1 - 0.0019 17.8 1.3 2 8.0 0.1 2.4 2 0 0 2 2 2 2 Nsp1-like C-terminal region eIF3g PF12353.3 EIM79348.1 - 0.011 15.6 0.3 0.011 15.6 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Prefoldin_2 PF01920.15 EIM79348.1 - 0.02 14.6 0.3 9.5 6.0 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit Retrotrans_gag PF03732.12 EIM79348.1 - 0.028 14.4 0.0 36 4.5 0.0 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein RE_MjaI PF09568.5 EIM79348.1 - 0.034 13.6 1.0 7.5 6.0 0.1 2.4 2 0 0 2 2 2 0 MjaI restriction endonuclease zf-CCHC_2 PF13696.1 EIM79348.1 - 0.1 12.1 0.1 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM79348.1 - 0.14 11.7 2.0 0.29 10.6 1.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF515 PF04415.7 EIM79350.1 - 0.036 12.3 12.8 0.043 12.0 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PAP1 PF08601.5 EIM79350.1 - 0.54 9.8 7.2 0.76 9.3 5.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3123 PF11321.3 EIM79350.1 - 4.8 7.4 7.4 7.3 6.9 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3123) GMC_oxred_N PF00732.14 EIM79352.1 - 2.5e-60 204.1 0.0 3.2e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM79352.1 - 1.5e-33 116.1 0.0 7.6e-33 113.8 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EIM79352.1 - 3.8e-05 22.7 0.2 0.0007 18.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM79352.1 - 4.9e-05 23.2 0.1 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM79352.1 - 0.00026 20.0 0.1 0.0011 17.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM79352.1 - 0.00063 18.7 0.4 0.0012 17.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM79352.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79352.1 - 0.01 14.3 0.1 0.026 13.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EIM79352.1 - 0.093 11.8 0.1 0.2 10.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 EIM79354.1 - 4e-48 163.8 0.0 4.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM79354.1 - 2.5e-25 89.0 0.0 1.3e-24 86.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM79354.1 - 2.4e-08 33.3 0.0 3.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM79354.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM79354.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family ADH_N PF08240.7 EIM79355.1 - 2.7e-26 91.4 4.3 4.7e-26 90.6 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM79355.1 - 3e-16 59.1 0.0 2.2e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM79355.1 - 0.0097 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM79355.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain mono-CXXC PF15626.1 EIM79355.1 - 2.7 8.0 5.4 0.36 10.7 0.3 2.0 2 0 0 2 2 2 0 single CXXC unit TPR_MLP1_2 PF07926.7 EIM79357.1 - 8.7e-21 74.0 20.7 8.7e-21 74.0 14.4 15.8 5 5 9 14 14 14 3 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIM79357.1 - 0.0014 17.7 15.4 0.0014 17.7 10.7 14.2 3 3 9 15 15 15 6 Autophagy protein Apg6 YvrJ PF12841.2 EIM79357.1 - 8 5.8 5.1 2.8 7.2 0.0 3.1 3 0 0 3 3 3 0 YvrJ protein family Ecl1 PF12855.2 EIM79358.1 - 0.037 13.3 0.4 0.076 12.3 0.3 1.5 1 0 0 1 1 1 0 Life-span regulatory factor ADH_N PF08240.7 EIM79359.1 - 5.6e-27 93.6 6.0 1e-26 92.8 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM79359.1 - 5.5e-19 68.0 0.0 1.2e-16 60.4 0.0 2.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM79359.1 - 0.0078 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EIM79359.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.16 EIM79359.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EIM79359.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF420 PF04238.7 EIM79361.1 - 0.041 13.8 2.8 0.085 12.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Syndecan PF01034.15 EIM79362.1 - 0.00076 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Shisa PF13908.1 EIM79362.1 - 0.00095 19.3 0.2 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 EIM79362.1 - 0.0017 17.5 0.2 0.0039 16.4 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EIM79362.1 - 0.0047 16.4 2.1 0.008 15.7 1.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EIM79362.1 - 0.083 11.1 0.1 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EIM79362.1 - 0.097 12.0 0.2 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HECT PF00632.20 EIM79363.1 - 1.6e-94 316.5 0.0 2.2e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EIM79363.1 - 0.0029 17.0 0.3 0.0029 17.0 0.2 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif p450 PF00067.17 EIM79365.1 - 1.5e-58 198.4 0.0 2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EIM79365.1 - 0.038 13.5 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Reticulon SET PF00856.23 EIM79366.1 - 5.3e-12 46.3 0.0 1.4e-10 41.7 0.0 2.4 1 1 0 1 1 1 1 SET domain DUF932 PF06067.6 EIM79366.1 - 0.08 12.2 0.7 0.13 11.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Glyco_hydro_18 PF00704.23 EIM79367.1 - 1.9e-59 201.8 1.7 3.8e-59 200.8 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2092 PF09865.4 EIM79367.1 - 0.28 10.2 0.0 0.49 9.4 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF3154 PF11351.3 EIM79368.1 - 0.09 12.5 0.6 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF4149 PF13664.1 EIM79368.1 - 1.9 8.6 9.0 5.7 7.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Colicin_V PF02674.11 EIM79368.1 - 3.7 7.3 10.2 0.068 13.0 0.4 2.6 3 0 0 3 3 3 0 Colicin V production protein stn_TNFRSF12A PF12191.3 EIM79369.1 - 0.062 13.3 0.2 0.062 13.3 0.2 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Rifin_STEVOR PF02009.11 EIM79369.1 - 0.25 10.9 0.1 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Peptidase_A4 PF01828.12 EIM79371.1 - 2e-75 252.4 13.4 2.2e-75 252.2 9.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.12 EIM79372.1 - 2.7e-69 232.3 8.4 2.7e-69 232.3 5.8 1.8 2 0 0 2 2 2 1 Peptidase A4 family Abhydrolase_6 PF12697.2 EIM79373.1 - 3.4e-22 79.4 0.0 4.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM79373.1 - 1e-09 38.2 0.1 5.7e-09 35.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM79373.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM79373.1 - 0.00065 19.9 0.1 0.0017 18.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EIM79373.1 - 0.006 15.0 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 EIM79373.1 - 0.026 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF915 PF06028.6 EIM79373.1 - 0.14 11.2 0.1 0.27 10.2 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Dimer_Tnp_hAT PF05699.9 EIM79378.1 - 4.3e-05 23.0 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region GST_C_3 PF14497.1 EIM79385.1 - 0.033 14.6 0.5 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Gly-zipper_Omp PF13488.1 EIM79387.1 - 0.039 13.5 11.0 0.54 9.9 2.0 2.4 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EIM79387.1 - 0.067 12.7 11.9 0.89 9.1 1.1 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EIM79387.1 - 0.24 11.0 6.2 2.3 7.8 0.5 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EIM79387.1 - 2.7 7.7 13.1 3 7.6 1.6 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Peptidase_A4 PF01828.12 EIM79390.1 - 7.1e-70 234.2 8.5 8e-70 234.1 5.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_M6 PF05547.6 EIM79390.1 - 0.026 12.5 0.1 0.028 12.4 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 AA_permease PF00324.16 EIM79391.1 - 0.016 13.5 1.5 0.024 12.9 0.1 2.0 2 1 0 2 2 2 0 Amino acid permease WD40 PF00400.27 EIM79392.1 - 4.6e-108 349.6 18.8 1.4e-13 50.1 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat NACHT PF05729.7 EIM79392.1 - 8.8e-08 31.9 0.1 2.8e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 NACHT domain BBS2_Mid PF14783.1 EIM79392.1 - 1.3e-07 31.3 0.5 16 5.3 0.0 7.7 7 1 1 8 8 8 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EIM79392.1 - 2.6e-07 30.6 0.0 35 4.8 0.0 7.3 6 2 1 7 7 7 0 PQQ-like domain eIF2A PF08662.6 EIM79392.1 - 2.3e-06 27.4 0.0 0.023 14.4 0.0 3.6 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIM79392.1 - 0.0001 21.8 0.7 99 2.7 0.0 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EIM79392.1 - 0.0015 18.5 0.2 0.011 15.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Y1_Tnp PF01797.11 EIM79392.1 - 0.011 15.5 0.1 0.068 13.0 0.1 2.2 2 0 0 2 2 2 0 Transposase IS200 like AAA_22 PF13401.1 EIM79392.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EIM79393.1 - 2.7e-46 153.8 4.5 1.4e-12 47.0 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat MerR_1 PF13411.1 EIM79393.1 - 0.00023 20.8 0.0 6.8 6.5 0.0 3.5 4 0 0 4 4 4 2 MerR HTH family regulatory protein BBS2_Mid PF14783.1 EIM79393.1 - 0.00052 19.7 0.0 15 5.4 0.0 4.0 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 EIM79393.1 - 0.0014 18.2 0.3 17 5.2 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIM79393.1 - 0.003 16.3 0.3 1.9 7.1 0.1 3.6 2 1 1 3 3 3 1 Nup133 N terminal like MerR PF00376.18 EIM79393.1 - 0.024 14.1 0.0 8.3 6.0 0.0 3.1 3 0 0 3 3 3 0 MerR family regulatory protein zf-MYND PF01753.13 EIM79394.1 - 1.1e-10 41.1 12.1 1.1e-10 41.1 8.4 2.5 2 1 1 3 3 3 1 MYND finger AA_permease_2 PF13520.1 EIM79395.1 - 1e-57 195.6 48.6 1.2e-57 195.3 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM79395.1 - 2.3e-16 59.2 39.4 3.1e-16 58.7 27.3 1.2 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.15 EIM79395.1 - 0.2 11.2 4.0 9.6 5.8 0.0 3.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex zf-MYND PF01753.13 EIM79399.1 - 1.1e-10 41.1 16.4 5.1e-10 39.0 11.4 2.1 1 1 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EIM79399.1 - 7.9 5.8 9.5 0.45 9.8 1.3 2.4 2 0 0 2 2 2 0 Life-span regulatory factor zf-ribbon_3 PF13248.1 EIM79400.1 - 0.06 12.5 2.1 0.27 10.4 1.5 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EIM79400.1 - 0.069 13.4 1.8 0.61 10.4 1.2 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 EIM79400.1 - 0.12 11.7 1.0 0.25 10.6 0.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding MFS_1 PF07690.11 EIM79402.1 - 1.6e-23 83.0 30.2 2.5e-16 59.3 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79402.1 - 4.3e-16 58.5 14.7 1e-15 57.3 10.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter 7tm_1 PF00001.16 EIM79403.1 - 0.0021 17.2 0.1 0.0063 15.6 0.1 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PEMT PF04191.8 EIM79407.1 - 1.9e-12 47.1 3.7 7.3e-12 45.3 0.8 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIM79407.1 - 4.1e-12 46.1 0.1 9e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIM79407.1 - 3.4e-06 25.8 0.1 1e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM79407.1 - 0.063 12.5 1.0 0.13 11.5 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Abhydrolase_3 PF07859.8 EIM79408.1 - 1.7e-13 50.6 0.0 6.1e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM79408.1 - 2.7e-11 43.4 0.0 9e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM79408.1 - 6.1e-11 41.9 0.0 2.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIM79408.1 - 5e-05 23.2 0.3 0.00016 21.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIM79408.1 - 0.00028 20.2 0.0 0.085 12.1 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family COesterase PF00135.23 EIM79408.1 - 0.0082 14.8 0.1 0.63 8.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.7 EIM79408.1 - 0.016 13.6 0.0 0.058 11.8 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIM79408.1 - 0.02 14.3 0.1 0.097 12.1 0.0 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase zf-MYND PF01753.13 EIM79409.1 - 8.8e-09 35.1 15.2 8.8e-09 35.1 10.6 2.1 2 0 0 2 2 2 1 MYND finger DUF2335 PF10097.4 EIM79409.1 - 0.012 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Carboxyl_trans PF01039.17 EIM79410.1 - 0.015 13.6 0.0 0.019 13.3 0.0 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain 7tm_2 PF00002.19 EIM79411.1 - 0.017 14.2 2.0 0.041 12.9 1.4 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) Aminotran_1_2 PF00155.16 EIM79412.1 - 2.7e-41 141.7 0.0 3.1e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIM79412.1 - 7e-06 25.3 0.3 1e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIM79412.1 - 7.3e-06 24.5 0.0 1.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIM79412.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 EIM79412.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FAD-oxidase_C PF02913.14 EIM79413.1 - 3.6e-51 173.8 0.1 6.5e-51 173.0 0.0 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIM79413.1 - 1.9e-30 105.1 0.0 3.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Dsl1_C PF11989.3 EIM79415.1 - 0.039 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal PQ-loop PF04193.9 EIM79416.1 - 2e-18 65.6 3.6 2.5e-09 36.5 0.0 3.7 3 0 0 3 3 3 3 PQ loop repeat Ank_2 PF12796.2 EIM79418.1 - 6.3e-15 55.2 0.0 6.7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM79418.1 - 1.2e-14 53.2 0.1 2e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EIM79418.1 - 9.6e-12 45.0 0.0 9.6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM79418.1 - 2.9e-09 36.2 0.0 0.00025 20.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIM79418.1 - 1e-07 31.9 0.0 0.00024 21.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.5 EIM79418.1 - 0.0018 18.3 1.0 0.026 14.5 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Ank PF00023.25 EIM79419.1 - 1.3e-14 53.1 1.1 5.3e-07 29.1 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIM79419.1 - 1.2e-13 51.2 0.1 1.3e-13 51.0 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM79419.1 - 1.1e-11 44.8 0.2 1.3e-11 44.7 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM79419.1 - 8.3e-11 41.0 0.4 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIM79419.1 - 1e-08 35.1 0.6 0.0012 19.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM79420.1 - 1.3e-24 86.1 4.3 2e-07 31.3 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM79420.1 - 1.9e-23 82.5 1.0 2.5e-10 40.5 0.1 2.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM79420.1 - 1.1e-22 78.6 6.0 4.3e-05 23.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EIM79420.1 - 3.4e-14 51.5 0.2 0.014 15.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIM79420.1 - 2.2e-11 43.6 3.9 0.00048 20.2 0.3 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3396 PF11876.3 EIM79420.1 - 0.57 9.2 3.3 1 8.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3396) YadA_head PF05658.9 EIM79421.1 - 2.2 8.6 7.4 1.5 9.1 1.3 2.5 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin F-box-like PF12937.2 EIM79422.1 - 3.2e-06 26.7 1.0 3.2e-06 26.7 0.7 2.3 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EIM79422.1 - 5.3 7.6 6.9 1.3e+02 3.4 0.1 4.9 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EIM79423.1 - 5.2e-06 26.0 0.5 1.8e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like Myc_target_1 PF15179.1 EIM79424.1 - 0.048 13.2 0.6 0.074 12.6 0.4 1.3 1 0 0 1 1 1 0 Myc target protein 1 Helitron_like_N PF14214.1 EIM79425.1 - 3e-05 23.8 0.0 0.00014 21.6 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF753 PF05444.7 EIM79425.1 - 0.046 13.6 3.6 0.11 12.3 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF753) PIF1 PF05970.9 EIM79426.1 - 0.091 11.6 0.2 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase UvrD_C_2 PF13538.1 EIM79427.1 - 0.064 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Phytase PF02333.10 EIM79428.1 - 0.044 12.4 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 Phytase CHAT PF12770.2 EIM79429.1 - 5.5e-37 127.4 0.0 1.1e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EIM79429.1 - 1.5e-20 72.8 8.9 0.004 17.0 0.0 9.2 4 2 4 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EIM79429.1 - 1e-18 66.7 5.1 0.0016 18.0 0.0 8.3 4 2 4 8 8 8 5 TPR repeat TPR_2 PF07719.12 EIM79429.1 - 1.9e-07 30.4 4.8 6.6 6.9 0.0 9.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM79429.1 - 2.6e-06 27.5 9.3 15 6.5 0.0 7.4 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM79429.1 - 6.9e-05 22.3 0.1 13 5.8 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIM79429.1 - 0.00021 21.1 11.4 0.19 11.7 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM79429.1 - 0.00046 19.6 2.4 59 3.5 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM79429.1 - 0.0007 20.2 5.2 0.63 10.7 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM79429.1 - 0.0028 17.3 7.6 6.5 6.8 0.0 7.7 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM79429.1 - 0.082 13.2 5.0 23 5.4 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ubiquitin PF00240.18 EIM79430.1 - 1.2e-15 56.6 0.4 1.6e-15 56.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM79430.1 - 2.7e-07 30.1 0.7 3.7e-07 29.7 0.5 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIM79430.1 - 0.0004 20.5 0.0 0.00047 20.2 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EIM79430.1 - 0.0041 17.3 0.4 0.017 15.3 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain PHD PF00628.24 EIM79431.1 - 0.0034 17.0 4.5 0.0034 17.0 3.1 2.3 2 0 0 2 2 2 1 PHD-finger eIF3_N PF09440.5 EIM79432.1 - 8.4e-46 155.4 4.2 2.3e-44 150.8 2.7 2.5 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EIM79432.1 - 3.1e-09 37.1 0.4 1.3e-08 35.0 0.1 2.2 2 1 1 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EIM79432.1 - 0.0074 16.0 0.1 0.025 14.3 0.0 2.0 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 PARP_reg PF02877.9 EIM79432.1 - 0.064 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Dor1 PF04124.7 EIM79434.1 - 6.9e-12 44.4 0.0 1.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Dor1-like family Zip PF02535.17 EIM79434.1 - 1.9 7.3 3.9 3.3 6.6 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-B_box PF00643.19 EIM79436.1 - 0.0026 17.5 6.7 0.0026 17.5 4.6 2.2 2 0 0 2 2 2 1 B-box zinc finger Tet_JBP PF12851.2 EIM79437.1 - 1e-08 34.6 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM79437.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Asp_protease_2 PF13650.1 EIM79438.1 - 1.7e-08 34.8 0.0 4.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIM79438.1 - 0.0083 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease K_trans PF02705.11 EIM79439.1 - 9.3e-50 169.4 2.4 9.3e-50 169.4 1.7 1.7 2 0 0 2 2 2 1 K+ potassium transporter APH PF01636.18 EIM79440.1 - 1.2e-15 57.9 0.0 1.6e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM79440.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EIM79440.1 - 0.0053 15.4 0.0 0.024 13.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 EIM79440.1 - 0.063 12.4 0.0 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 EIM79440.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase K_trans PF02705.11 EIM79443.1 - 5.5e-174 579.4 11.5 7.9e-174 578.9 8.0 1.2 1 0 0 1 1 1 1 K+ potassium transporter RhoGAP PF00620.22 EIM79444.1 - 6.9e-15 54.9 0.0 1.1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF2353 PF09789.4 EIM79445.1 - 3.1 6.9 51.7 0.36 10.0 18.0 3.4 1 1 3 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) HAUS4 PF14735.1 EIM79446.1 - 0.079 12.2 7.4 0.12 11.6 5.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 APH PF01636.18 EIM79448.1 - 3.6e-13 49.8 0.0 5.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM79448.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.24 EIM79449.1 - 1.9e-18 66.9 0.0 3.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM79449.1 - 6e-06 26.4 0.4 0.00019 21.5 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM79449.1 - 7.8e-06 25.9 0.1 7.6e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EIM79449.1 - 0.00018 21.2 0.1 0.00018 21.2 0.1 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 EIM79449.1 - 0.00065 19.4 0.1 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIM79449.1 - 0.00098 19.9 0.0 0.0036 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIM79449.1 - 0.0028 17.2 0.1 0.0082 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM79449.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM79449.1 - 0.01 15.4 0.6 0.019 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIM79449.1 - 0.013 15.7 0.0 0.049 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIM79449.1 - 0.028 14.3 0.4 0.097 12.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EIM79449.1 - 0.03 14.5 0.1 0.47 10.6 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.1 EIM79449.1 - 0.034 14.0 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.3 EIM79449.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RuvB_N PF05496.7 EIM79449.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zot PF05707.7 EIM79449.1 - 0.063 12.7 0.1 9.6 5.6 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_2 PF07724.9 EIM79449.1 - 0.074 12.9 0.3 0.17 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EIM79449.1 - 0.17 10.9 0.2 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI BTB PF00651.26 EIM79450.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.13 EIM79451.1 - 2.4e-09 36.9 12.8 5.7e-09 35.6 8.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM79451.1 - 0.26 11.1 3.3 0.62 9.9 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TSP_3 PF02412.13 EIM79452.1 - 0.0011 18.3 9.1 0.0019 17.6 0.3 2.7 3 0 0 3 3 3 2 Thrombospondin type 3 repeat Toxin_44 PF15523.1 EIM79452.1 - 0.88 9.4 3.6 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Putative toxin 44 Aminotran_5 PF00266.14 EIM79453.1 - 1.3e-40 139.3 0.0 1.8e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V CFEM PF05730.6 EIM79454.1 - 8.1e-11 41.5 9.7 1.2e-10 41.0 6.7 1.2 1 0 0 1 1 1 1 CFEM domain Apolipoprotein PF01442.13 EIM79455.1 - 0.0049 16.4 3.2 0.0065 16.0 2.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EIM79455.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mitofilin PF09731.4 EIM79455.1 - 0.17 10.5 7.4 0.19 10.3 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FUSC PF04632.7 EIM79455.1 - 1.6 7.0 10.2 2.3 6.5 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.24 EIM79456.1 - 1.1e-17 64.4 0.0 2.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM79456.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM79456.1 - 1.5e-05 25.1 1.2 0.0013 18.9 0.8 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIM79456.1 - 2.8e-05 23.7 0.9 0.00011 21.8 0.0 2.4 3 0 0 3 3 2 1 Part of AAA domain AAA_17 PF13207.1 EIM79456.1 - 0.00015 22.5 0.1 0.001 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM79456.1 - 0.00042 20.0 0.2 0.0024 17.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIM79456.1 - 0.00098 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIM79456.1 - 0.0011 18.6 0.1 0.0031 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIM79456.1 - 0.0023 18.2 0.0 0.012 15.9 0.0 2.2 2 1 1 3 3 2 1 AAA domain AAA_11 PF13086.1 EIM79456.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIM79456.1 - 0.0079 16.1 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIM79456.1 - 0.026 14.5 0.6 0.12 12.3 0.0 2.4 2 1 1 3 3 2 0 AAA domain RuvB_N PF05496.7 EIM79456.1 - 0.047 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EIM79456.1 - 0.066 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Vps36_ESCRT-II PF11605.3 EIM79456.1 - 0.081 12.7 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 1 0 Vacuolar protein sorting protein 36 Vps36 Zot PF05707.7 EIM79456.1 - 0.095 12.1 0.0 3 7.2 0.0 2.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EIM79456.1 - 0.15 11.2 0.2 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UIM PF02809.15 EIM79456.1 - 0.72 9.5 3.2 3.3 7.5 2.2 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif CrtC PF07143.6 EIM79457.1 - 0.00015 21.1 0.1 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) GMC_oxred_N PF00732.14 EIM79458.1 - 2.4e-66 223.8 0.0 3e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM79458.1 - 1.2e-37 129.3 0.0 3e-37 128.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EIM79458.1 - 1.1e-05 24.5 0.0 7.5e-05 21.7 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM79458.1 - 0.0001 21.2 0.3 0.009 14.9 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIM79458.1 - 0.00012 22.0 0.4 0.00031 20.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM79458.1 - 0.00034 19.6 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM79458.1 - 0.0011 18.8 0.0 0.0051 16.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79458.1 - 0.015 13.7 0.0 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EIM79458.1 - 0.024 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM79458.1 - 0.054 12.5 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EIM79458.1 - 0.089 11.8 0.1 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIM79458.1 - 0.18 10.4 0.2 0.25 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase STE2 PF02116.10 EIM79459.1 - 0.00049 19.2 13.3 0.0026 16.8 9.3 2.0 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metal_resist PF13801.1 EIM79459.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Coprogen_oxidas PF01218.13 EIM79460.1 - 9.7e-73 244.2 0.0 6.3e-71 238.3 0.0 3.0 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase GMC_oxred_N PF00732.14 EIM79461.1 - 1.6e-68 231.0 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM79461.1 - 9.1e-37 126.5 0.0 1.6e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM79461.1 - 5e-06 25.6 0.2 0.0089 14.9 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM79461.1 - 8.8e-06 24.8 0.0 7.4e-05 21.8 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM79461.1 - 0.00012 21.9 0.4 0.00031 20.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM79461.1 - 0.00045 19.2 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM79461.1 - 0.0021 17.9 0.0 0.0092 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79461.1 - 0.0083 14.6 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EIM79461.1 - 0.029 14.7 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM79461.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EIM79461.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIM79461.1 - 0.18 10.3 0.2 0.25 9.9 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF948 PF06103.6 EIM79462.1 - 2.9 7.8 5.5 28 4.6 0.5 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GAGA_bind PF06217.7 EIM79462.1 - 8.6 6.2 16.0 1.4 8.7 2.0 3.8 2 1 2 4 4 4 0 GAGA binding protein-like family DUF2235 PF09994.4 EIM79463.1 - 1.1e-58 198.8 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Dimer_Tnp_hAT PF05699.9 EIM79464.1 - 8.4e-12 44.5 0.0 1.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Androgen_recep PF02166.11 EIM79464.1 - 0.038 12.8 2.1 0.092 11.6 1.4 1.6 1 1 1 2 2 2 0 Androgen receptor CFEM PF05730.6 EIM79465.1 - 2.1e-09 37.0 17.6 4.6e-09 35.9 12.2 1.6 1 0 0 1 1 1 1 CFEM domain Toxin_3 PF00537.13 EIM79465.1 - 0.061 13.2 1.4 0.15 11.9 0.9 1.6 1 0 0 1 1 1 0 Scorpion toxin-like domain Gamma-thionin PF00304.15 EIM79465.1 - 1.5 8.9 7.2 0.14 12.1 1.8 1.7 2 0 0 2 2 2 0 Gamma-thionin family DUF2217 PF10265.4 EIM79465.1 - 9.8 4.8 10.0 12 4.5 6.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CFEM PF05730.6 EIM79466.1 - 2.2e-11 43.3 13.6 5.1e-11 42.2 9.4 1.6 1 0 0 1 1 1 1 CFEM domain Rifin_STEVOR PF02009.11 EIM79466.1 - 6.2 6.3 6.8 8.8 5.8 4.7 1.3 1 0 0 1 1 1 0 Rifin/stevor family F-box-like PF12937.2 EIM79467.1 - 7.2e-07 28.8 5.5 2.4e-06 27.1 3.8 2.0 1 0 0 1 1 1 1 F-box-like TMEM51 PF15345.1 EIM79468.1 - 0.0044 16.7 0.5 0.0085 15.8 0.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Plasmodium_Vir PF05795.6 EIM79468.1 - 0.0078 15.4 3.9 0.0079 15.4 1.9 1.5 2 0 0 2 2 2 1 Plasmodium vivax Vir protein DUF2576 PF10845.3 EIM79468.1 - 0.015 14.4 2.2 1.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF1191 PF06697.7 EIM79468.1 - 0.024 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Macoilin PF09726.4 EIM79468.1 - 2.2 6.4 7.6 3.5 5.7 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein iPGM_N PF06415.8 EIM79471.1 - 1.5e-73 246.8 0.0 2.4e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EIM79471.1 - 1.3e-71 240.9 0.0 2.5e-71 240.0 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EIM79471.1 - 2.2e-05 23.7 0.1 0.00034 19.9 0.1 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EIM79471.1 - 3.8e-05 23.1 0.0 0.00012 21.4 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.19 EIM79471.1 - 0.021 14.0 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PglZ PF08665.7 EIM79471.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 PglZ domain RicinB_lectin_2 PF14200.1 EIM79473.1 - 1.7e-09 37.9 9.8 9.4e-05 22.7 0.1 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Botulinum_HA-17 PF05588.6 EIM79473.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Clostridium botulinum HA-17 protein CDtoxinA PF03498.9 EIM79473.1 - 0.044 13.1 3.7 0.32 10.3 0.1 2.8 2 1 1 3 3 3 0 Cytolethal distending toxin A/C family CBM_2 PF00553.14 EIM79473.1 - 0.46 10.5 10.8 1.3 9.0 0.6 2.7 2 1 0 2 2 2 0 Cellulose binding domain p450 PF00067.17 EIM79474.1 - 2.9e-60 204.1 0.0 3.2e-33 114.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CHAT PF12770.2 EIM79475.1 - 1.8e-25 89.6 0.3 5.6e-25 88.0 0.1 1.8 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EIM79475.1 - 0.012 15.5 20.3 0.53 10.2 0.1 5.6 4 2 4 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM79475.1 - 0.015 15.1 5.1 24 5.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM79475.1 - 0.15 12.8 14.4 0.85 10.4 0.1 6.9 5 1 3 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM79475.1 - 0.87 9.3 5.1 42 3.9 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIM79475.1 - 9.7 6.6 11.4 6.7 7.1 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 EIM79476.1 - 2.8e-12 47.1 0.0 3.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATE_N PF04376.8 EIM79479.1 - 0.044 13.5 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Lactamase_B PF00753.22 EIM79480.1 - 1.6e-06 27.9 0.4 6.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM79480.1 - 0.00044 19.8 0.1 0.00097 18.7 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.2 EIM79481.1 - 0.002 17.8 0.4 0.002 17.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like DUF1479 PF07350.7 EIM79482.1 - 2e-65 220.9 0.0 2.4e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) NACHT PF05729.7 EIM79483.1 - 3.1e-06 26.9 0.1 8.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIM79483.1 - 6.5e-06 26.3 0.1 2.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pkinase PF00069.20 EIM79483.1 - 1e-05 24.8 0.2 2e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM79483.1 - 3.1e-05 23.8 0.5 0.0013 18.5 0.3 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA_16 PF13191.1 EIM79483.1 - 0.00016 21.6 0.4 0.0016 18.4 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain KaiC PF06745.8 EIM79483.1 - 0.11 11.5 0.0 15 4.5 0.0 2.4 2 0 0 2 2 2 0 KaiC Peptidase_C14 PF00656.17 EIM79484.1 - 3.4e-20 72.7 0.0 5.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM79484.1 - 0.18 11.6 0.0 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain CHAT PF12770.2 EIM79485.1 - 6.9e-36 123.8 0.0 1.7e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM79485.1 - 2e-10 40.4 0.6 0.69 9.8 0.0 7.2 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIM79485.1 - 3.1e-07 29.9 2.7 12 5.6 0.0 7.5 5 3 3 8 8 8 3 TPR repeat TPR_8 PF13181.1 EIM79485.1 - 0.087 12.6 0.0 16 5.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EIM79486.1 - 5.2e-27 94.6 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM79486.1 - 1.2e-11 44.2 0.0 1.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM79486.1 - 7.8e-08 32.3 0.1 0.0037 17.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EIM79486.1 - 0.012 14.6 0.0 0.031 13.2 0.0 1.7 1 1 1 2 2 2 0 Fructosamine kinase CHAT PF12770.2 EIM79489.1 - 4.9e-11 42.2 0.1 6.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Spo7_2_N PF15407.1 EIM79489.1 - 0.051 13.0 0.1 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 Milton PF12448.3 EIM79491.1 - 0.021 15.0 2.2 0.9 9.7 0.2 2.9 3 0 0 3 3 3 0 Kinesin associated protein CDC45 PF02724.9 EIM79494.1 - 0.047 11.7 3.8 0.062 11.3 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3779 PF12621.3 EIM79494.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphate metabolism protein Trypan_PARP PF05887.6 EIM79494.1 - 0.15 11.8 6.8 0.25 11.1 4.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 EIM79494.1 - 0.2 9.5 11.5 0.26 9.1 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family PCIF1_WW PF12237.3 EIM79495.1 - 0.11 11.7 0.8 4.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain ORC6 PF05460.8 EIM79495.1 - 0.18 10.8 5.0 0.28 10.2 3.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mito_fiss_reg PF05308.6 EIM79495.1 - 0.34 10.2 6.4 0.86 8.9 4.5 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Soyouz_module PF14313.1 EIM79495.1 - 1.2 8.7 4.4 0.42 10.1 0.2 2.3 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Nop14 PF04147.7 EIM79495.1 - 1.4 6.7 5.7 1.8 6.3 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIM79495.1 - 2.6 5.9 3.7 4 5.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CAP_N PF01213.14 EIM79495.1 - 2.8 7.1 6.3 5.5 6.1 4.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sporozoite_P67 PF05642.6 EIM79496.1 - 0.15 9.9 3.9 0.2 9.4 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Serinc PF03348.10 EIM79498.1 - 0.27 9.9 1.6 0.45 9.1 1.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 EIM79498.1 - 0.34 8.5 5.7 0.51 7.9 4.0 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 EIM79498.1 - 0.35 10.3 19.0 0.66 9.4 13.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAGA_bind PF06217.7 EIM79498.1 - 3.7 7.4 9.7 8.9 6.1 6.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EIM79498.1 - 5.2 6.7 8.1 9.4 5.9 5.6 1.3 1 0 0 1 1 1 0 DDHD domain Gly-rich_Ago1 PF12764.2 EIM79498.1 - 5.6 7.6 8.6 15 6.2 5.9 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut YqfQ PF14181.1 EIM79498.1 - 8.5 6.3 15.3 16 5.4 10.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein Serglycin PF04360.7 EIM79499.1 - 0.17 11.5 7.3 0.16 11.6 2.6 2.6 3 0 0 3 3 3 0 Serglycin NAD_binding_8 PF13450.1 EIM79500.1 - 1.2e-09 38.1 0.0 2.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM79500.1 - 1.8e-06 28.2 0.0 5.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM79500.1 - 1.4e-05 24.3 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EIM79500.1 - 1.5e-05 24.3 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EIM79500.1 - 3.2e-05 23.1 0.0 4.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EIM79500.1 - 3.3e-05 23.8 0.1 0.00011 22.1 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79500.1 - 0.00032 19.3 0.0 0.00046 18.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EIM79500.1 - 0.00083 18.3 0.0 0.0039 16.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM79500.1 - 0.005 15.7 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIM79500.1 - 0.01 15.6 0.1 0.16 11.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EIM79500.1 - 0.025 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM79500.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM79500.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EIM79500.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-MYND PF01753.13 EIM79501.1 - 4.2e-08 32.9 17.6 9e-08 31.8 12.2 1.6 1 0 0 1 1 1 1 MYND finger BiPBP_C PF06832.7 EIM79501.1 - 0.13 12.2 0.1 0.48 10.3 0.1 1.9 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family WD40 PF00400.27 EIM79503.1 - 3e-157 505.6 67.8 7.9e-13 47.7 0.1 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIM79503.1 - 2.7e-15 55.5 19.9 0.00048 18.5 0.1 6.4 1 1 6 7 7 7 7 Cytochrome D1 heme domain NACHT PF05729.7 EIM79503.1 - 2e-07 30.7 0.0 1.4e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 NACHT domain DUF3312 PF11768.3 EIM79503.1 - 1.8e-06 26.4 0.0 0.52 8.4 0.0 4.6 4 1 1 5 5 5 2 Protein of unknown function (DUF3312) AAA_16 PF13191.1 EIM79503.1 - 7.9e-06 25.9 0.4 5.9e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain CNH PF00780.17 EIM79503.1 - 0.00026 20.4 0.7 8.3 5.7 0.0 6.8 8 1 2 10 10 10 1 CNH domain NB-ARC PF00931.17 EIM79503.1 - 0.0033 16.3 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 EIM79503.1 - 0.013 15.6 0.0 0.052 13.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.7 EIM79503.1 - 0.016 14.8 10.6 1.7e+02 1.9 0.0 8.9 10 0 0 10 10 8 0 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 EIM79503.1 - 0.057 14.2 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM79503.1 - 0.062 13.4 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM79503.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EIM79503.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_14 PF13173.1 EIM79503.1 - 0.14 12.0 0.0 3 7.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF4631 PF15450.1 EIM79503.1 - 0.51 8.5 0.3 0.86 7.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) YchF-GTPase_C PF06071.8 EIM79503.1 - 0.7 9.7 4.1 24 4.7 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF933) G-alpha PF00503.15 EIM79504.1 - 3.3e-122 407.9 0.3 4e-122 407.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM79504.1 - 7e-16 57.9 0.6 2e-09 36.9 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM79504.1 - 0.00062 18.9 0.1 0.76 8.8 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM79504.1 - 0.019 15.4 0.2 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EIM79504.1 - 0.064 12.6 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIM79504.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arylsulfotran_2 PF14269.1 EIM79505.1 - 2.4e-57 194.3 11.1 2.4e-57 194.3 7.7 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EIM79505.1 - 5.1e-19 68.1 12.8 3.6e-18 65.3 8.9 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) EphA2_TM PF14575.1 EIM79506.1 - 0.037 14.4 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain p450 PF00067.17 EIM79507.1 - 2.8e-61 207.4 0.0 1.4e-32 112.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIM79508.1 - 1.3e-44 152.4 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HEAT PF02985.17 EIM79509.1 - 3.8e-16 57.6 9.5 4.5e-07 29.3 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EIM79509.1 - 3.9e-14 52.6 2.4 1.3e-05 25.4 0.0 5.4 4 2 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EIM79509.1 - 2.4e-12 46.9 7.5 0.00014 22.2 0.0 7.3 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIM79509.1 - 3.6e-09 36.9 0.1 0.00011 22.5 0.0 3.8 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EIM79509.1 - 3.3e-07 30.1 0.4 0.0087 15.7 0.0 4.5 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EIM79509.1 - 6.6e-05 21.8 5.1 0.00081 18.2 0.0 3.0 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF4042 PF13251.1 EIM79509.1 - 0.091 12.2 1.9 1.8 7.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) BTB PF00651.26 EIM79510.1 - 0.0042 17.0 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CobT PF06213.7 EIM79510.1 - 0.015 14.4 6.9 0.027 13.6 4.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3154 PF11351.3 EIM79510.1 - 0.057 13.1 0.1 0.21 11.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Nucleoplasmin PF03066.10 EIM79510.1 - 0.21 11.0 8.1 0.38 10.2 5.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EIM79510.1 - 0.4 9.1 8.7 0.72 8.2 6.0 1.3 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EIM79510.1 - 1.5 7.5 14.2 2.7 6.6 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EIM79510.1 - 1.8 6.3 9.5 2.9 5.7 6.6 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 EIM79510.1 - 2.8 6.2 12.6 4.2 5.6 8.8 1.1 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 EIM79510.1 - 7.1 5.7 8.1 15 4.7 5.6 1.4 1 0 0 1 1 1 0 NOA36 protein RVT_1 PF00078.22 EIM79512.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIM79513.1 - 1.1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM79513.1 - 3.9e-05 23.8 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PapJ PF14855.1 EIM79513.1 - 0.12 11.8 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone SRP-alpha_N PF04086.8 EIM79514.1 - 0.1 11.9 8.7 0.21 10.9 6.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Phenol_MetA_deg PF13557.1 EIM79515.1 - 0.032 14.0 0.1 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation Sec34 PF04136.10 EIM79518.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Sec34-like family AAA_10 PF12846.2 EIM79519.1 - 1.1e-10 41.4 0.1 3.7e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EIM79519.1 - 4.4e-06 26.2 0.0 2.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EIM79519.1 - 0.0052 16.9 0.1 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM79519.1 - 0.05 13.7 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3328 PF11807.3 EIM79520.1 - 3.7e-46 157.5 0.4 4.7e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.18 EIM79523.1 - 6e-13 48.4 0.3 1.6e-12 47.0 0.2 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM79523.1 - 1.6e-08 34.2 0.1 3.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1212 PF06738.7 EIM79524.1 - 1.1e-36 126.0 1.9 1.1e-36 126.0 1.3 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM79524.1 - 2.7e-19 69.4 8.4 2.7e-19 69.4 5.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) PAP2 PF01569.16 EIM79524.1 - 0.00098 18.8 2.6 0.00098 18.8 1.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_A4 PF01828.12 EIM79525.1 - 9.4e-79 263.3 10.1 1.1e-78 263.0 7.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family SKN1 PF03935.10 EIM79526.1 - 1.2e-180 600.9 13.1 3e-180 599.6 9.1 1.6 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TM_helix PF05552.7 EIM79526.1 - 0.24 11.1 1.7 0.45 10.2 1.2 1.3 1 0 0 1 1 1 0 Conserved TM helix Patatin PF01734.17 EIM79527.1 - 1.2e-23 84.1 0.0 4.6e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_10 PF12846.2 EIM79532.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Dor1 PF04124.7 EIM79533.1 - 3.9e-35 120.9 0.0 4.4e-28 97.7 0.0 3.2 2 2 0 2 2 2 2 Dor1-like family COG2 PF06148.6 EIM79533.1 - 0.0056 16.5 0.7 0.0088 15.9 0.0 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EIM79533.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Vps51/Vps67 Baculo_PEP_C PF04513.7 EIM79533.1 - 0.45 10.3 2.5 1.1 9.0 1.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Patatin PF01734.17 EIM79535.1 - 3.5e-12 46.6 0.0 3.9e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 EIM79537.1 - 1.2e-137 444.5 3.7 4e-12 45.6 0.0 12.8 12 1 1 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.1 EIM79537.1 - 4.3e-87 286.1 1.3 1.9e-12 46.9 0.0 9.3 3 2 7 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 EIM79537.1 - 1.9e-32 108.4 14.3 0.053 13.3 0.0 11.9 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_17 PF13431.1 EIM79537.1 - 4.4e-22 76.3 0.5 2.4 8.5 0.0 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_4 PF07721.9 EIM79537.1 - 2.4e-17 61.5 5.0 13 6.5 0.0 11.0 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM79537.1 - 2.8e-17 61.5 0.0 5.5 6.7 0.0 10.7 11 0 0 11 11 11 2 Tetratricopeptide repeat Rab5-bind PF09311.6 EIM79537.1 - 6.4e-16 58.7 2.6 2 8.2 0.1 9.4 1 1 10 11 11 11 4 Rabaptin-like protein TPR_19 PF14559.1 EIM79537.1 - 3.3e-15 56.1 0.0 2.6 8.4 0.0 9.9 5 3 2 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM79537.1 - 4.5e-15 55.8 0.0 4.4 8.0 0.0 9.8 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM79537.1 - 2.2e-14 52.1 5.7 9.4 6.4 0.0 10.5 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM79537.1 - 1.9e-08 34.2 5.6 62 4.6 0.0 9.9 11 0 0 11 11 10 0 Tetratricopeptide repeat DUF3400 PF11880.3 EIM79537.1 - 3.5e-07 29.3 14.4 12 5.1 0.0 9.8 10 0 0 10 10 10 0 Domain of unknown function (DUF3400) TPR_8 PF13181.1 EIM79537.1 - 1.7e-05 24.2 0.0 51 3.9 0.0 8.1 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF1858 PF08984.6 EIM79537.1 - 5.8e-05 22.6 0.0 70 3.1 0.0 7.1 8 0 0 8 8 8 0 Domain of unknown function (DUF1858) PPR PF01535.15 EIM79537.1 - 0.00022 20.9 0.0 45 4.3 0.0 6.8 10 0 0 10 10 9 0 PPR repeat Proteasome_A_N PF10584.4 EIM79537.1 - 0.00077 18.7 4.8 77 2.7 0.0 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature FB_lectin PF07367.6 EIM79537.1 - 0.0074 15.8 28.8 23 4.5 0.0 9.5 2 2 8 10 10 10 0 Fungal fruit body lectin Peptidase_C5 PF00770.13 EIM79537.1 - 0.2 11.1 1.6 66 2.9 0.0 4.4 5 1 1 6 6 5 0 Adenovirus endoprotease TPR_6 PF13174.1 EIM79537.1 - 4.9 7.8 20.9 56 4.5 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat NACHT PF05729.7 EIM79538.1 - 5.9e-10 39.0 0.2 1.8e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIM79538.1 - 5.1e-07 29.8 0.2 7.7e-06 26.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIM79538.1 - 5.3e-05 23.3 0.1 0.00024 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIM79538.1 - 0.033 14.3 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EIM79538.1 - 0.048 12.5 0.0 0.35 9.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EIM79538.1 - 0.054 12.6 0.0 0.47 9.5 0.0 2.2 1 1 0 1 1 1 0 KaiC AAA PF00004.24 EIM79538.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Methyltransf_2 PF00891.13 EIM79539.1 - 1.8e-28 99.4 0.0 1.4e-26 93.2 0.0 2.3 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 EIM79539.1 - 0.0051 17.3 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 EIM79540.1 - 1.4e-26 93.3 0.0 2.1e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM79540.1 - 2.7e-11 42.7 0.0 2.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIM79540.1 - 6.2e-05 22.7 0.0 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM79540.1 - 0.0053 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EIM79540.1 - 0.047 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_30 PF02055.11 EIM79541.1 - 6.8e-21 74.0 0.6 8.8e-13 47.2 0.2 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EIM79541.1 - 1.3e-16 60.5 0.1 2.7e-16 59.4 0.1 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Acetyltransf_1 PF00583.19 EIM79542.1 - 5.1e-06 26.4 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM79542.1 - 8.5e-06 25.8 0.0 4.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM79542.1 - 0.028 14.5 0.1 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DOPA_dioxygen PF08883.6 EIM79543.1 - 1.8e-28 98.6 0.3 2.2e-28 98.3 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family TPR_12 PF13424.1 EIM79544.1 - 2e-19 69.2 0.6 2.5e-13 49.7 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM79544.1 - 1.4e-16 59.7 0.2 7.8e-09 35.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EIM79544.1 - 3.5e-09 35.9 0.0 1.3e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EIM79544.1 - 4.2e-06 26.5 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIM79544.1 - 0.00085 19.4 0.0 0.0029 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.1 EIM79544.1 - 0.005 16.5 0.5 0.97 9.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIM79544.1 - 0.047 14.1 0.2 0.66 10.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM79544.1 - 0.11 12.7 0.1 21 5.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 EIM79545.1 - 6.6e-23 81.6 1.2 7.9e-21 74.8 0.8 2.2 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM79545.1 - 0.00051 19.9 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain CHAT PF12770.2 EIM79545.1 - 0.0017 17.5 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Alph_Pro_TM PF09608.5 EIM79547.1 - 0.092 12.2 0.4 2.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) MRP-L20 PF12824.2 EIM79547.1 - 0.23 11.4 0.9 0.7 9.8 0.6 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Tub_2 PF04525.7 EIM79548.1 - 6.7e-28 97.3 0.0 8.1e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 MFS_1 PF07690.11 EIM79550.1 - 1.9e-21 76.1 21.8 2.9e-21 75.5 13.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIM79551.1 - 2.3e-41 141.6 35.6 2.3e-41 141.6 24.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79551.1 - 1e-07 30.9 10.4 1e-07 30.9 7.2 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EIM79551.1 - 0.0036 15.4 0.8 1.9 6.4 0.5 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.8 EIM79551.1 - 1.2 9.5 3.4 24 5.3 0.4 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Tub_2 PF04525.7 EIM79552.1 - 1.9e-14 53.4 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 p450 PF00067.17 EIM79553.1 - 9.6e-67 225.4 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIM79555.1 - 0.00024 20.7 0.0 0.0019 17.8 0.0 2.5 2 0 0 2 2 2 1 F-box-like RicinB_lectin_2 PF14200.1 EIM79557.1 - 1.9e-37 127.7 0.1 4.5e-09 36.6 0.0 6.8 4 1 3 7 7 7 7 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIM79557.1 - 1.7e-09 37.7 0.3 0.00094 19.2 0.0 4.6 3 1 3 6 6 6 4 Ricin-type beta-trefoil lectin domain DUF2414 PF10309.4 EIM79557.1 - 0.04 13.6 0.4 0.082 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) RicinB_lectin_2 PF14200.1 EIM79558.1 - 1.1e-05 25.7 0.4 0.12 12.7 0.0 3.5 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like DUF2235 PF09994.4 EIM79559.1 - 6.5e-59 199.5 0.2 9e-59 199.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) YvbH_ext PF11724.3 EIM79559.1 - 0.048 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 YvbH-like oligomerisation region Abhydrolase_2 PF02230.11 EIM79559.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.27 EIM79560.1 - 4e-148 476.6 46.6 9.9e-15 53.7 0.1 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIM79560.1 - 5.5e-17 62.1 0.0 0.00012 21.8 0.0 5.1 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIM79560.1 - 2.2e-13 49.5 14.4 2.9 7.6 0.0 10.4 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIM79560.1 - 1.4e-11 43.2 13.9 0.46 8.5 0.0 8.2 2 1 2 7 7 7 7 Nucleoporin Nup120/160 Gmad1 PF10647.4 EIM79560.1 - 4.2e-10 39.4 9.3 2e-05 24.1 0.7 4.8 3 2 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EIM79560.1 - 1.3e-09 37.3 5.2 0.028 13.1 0.0 6.8 1 1 3 6 6 6 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIM79560.1 - 2.5e-07 29.3 0.8 0.0035 15.7 0.0 4.6 1 1 4 5 5 5 1 Cytochrome D1 heme domain PQQ PF01011.16 EIM79560.1 - 2.9e-05 23.3 4.3 1.4 8.5 0.0 5.3 5 0 0 5 5 4 2 PQQ enzyme repeat Nbas_N PF15492.1 EIM79560.1 - 4.1e-05 22.8 6.2 4.6 6.2 0.1 6.8 1 1 4 7 7 7 1 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIM79560.1 - 0.00011 20.5 0.0 0.74 7.9 0.0 4.1 3 1 1 5 5 5 2 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 EIM79560.1 - 0.00012 21.5 9.1 0.0059 16.0 1.3 3.8 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EIM79560.1 - 0.00025 21.2 17.3 0.13 12.5 0.0 7.2 6 4 3 9 9 9 2 PQQ-like domain IKI3 PF04762.7 EIM79560.1 - 0.00067 17.6 0.0 0.062 11.1 0.0 3.4 2 2 2 4 4 4 1 IKI3 family Hira PF07569.6 EIM79560.1 - 0.0014 17.8 0.0 3.5 6.7 0.0 4.3 5 1 1 6 6 6 1 TUP1-like enhancer of split Proteasome_A_N PF10584.4 EIM79560.1 - 0.0014 17.8 19.8 12 5.3 0.0 9.1 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 EIM79560.1 - 0.0063 16.7 2.3 5.6 7.3 0.0 3.9 2 1 1 3 3 3 1 Resistin HPS3_N PF14761.1 EIM79560.1 - 0.013 14.9 0.0 3.8 6.8 0.0 2.9 4 0 0 4 4 4 0 Hermansky-Pudlak syndrome 3 DPPIV_N PF00930.16 EIM79560.1 - 0.019 13.5 1.4 34 2.8 0.0 5.4 3 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region MORN_2 PF07661.8 EIM79560.1 - 0.17 11.9 0.0 58 4.2 0.0 4.7 6 1 1 7 7 6 0 MORN repeat variant TFIIIC_delta PF12657.2 EIM79560.1 - 0.73 9.5 4.1 15 5.2 0.1 4.1 4 2 1 5 5 5 0 Transcription factor IIIC subunit delta N-term Chordopox_A13L PF05961.6 EIM79564.1 - 0.13 12.1 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein CRA PF06589.6 EIM79564.1 - 0.27 10.5 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) BacteriocIIc_cy PF12173.3 EIM79564.1 - 0.64 10.0 6.3 0.88 9.6 4.4 1.2 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF3040 PF11239.3 EIM79564.1 - 1.2 9.2 5.2 0.18 11.8 0.3 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1206 PF06724.6 EIM79564.1 - 6.6 6.5 15.3 42 3.9 10.6 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF2235 PF09994.4 EIM79565.1 - 3.1e-50 171.1 0.1 5.5e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.27 EIM79566.1 - 1.8e-138 446.0 51.6 2.8e-14 52.3 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EIM79566.1 - 1.4e-12 47.7 0.0 0.001 18.8 0.0 4.6 1 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIM79566.1 - 1.4e-10 40.9 14.5 2.7e-05 23.7 0.8 5.5 3 3 2 5 5 5 4 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIM79566.1 - 3.5e-10 39.2 14.8 2.8 7.6 0.0 9.6 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIM79566.1 - 2.8e-09 35.6 11.1 0.56 8.2 0.0 8.0 3 3 4 8 8 8 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIM79566.1 - 1.4e-07 30.1 1.6 0.018 13.3 0.0 4.7 2 2 3 5 5 5 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIM79566.1 - 3.5e-07 29.3 18.4 0.026 13.3 0.6 6.3 1 1 3 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 EIM79566.1 - 3.5e-06 26.3 5.7 0.069 12.2 0.0 6.3 4 3 3 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIM79566.1 - 5.9e-06 25.9 7.7 0.048 13.1 3.1 4.5 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 EIM79566.1 - 0.00029 20.2 6.7 3 7.5 0.1 5.5 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.1 EIM79566.1 - 0.0021 18.2 21.2 1.1 9.6 0.1 7.5 8 2 2 10 10 8 2 PQQ-like domain IKI3 PF04762.7 EIM79566.1 - 0.0074 14.1 0.1 1.8 6.2 0.0 2.6 1 1 1 3 3 3 2 IKI3 family HPS3_N PF14761.1 EIM79566.1 - 0.023 14.0 0.0 0.57 9.5 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Proteasome_A_N PF10584.4 EIM79566.1 - 0.026 13.8 16.2 31 4.0 0.0 7.8 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Apc4_WD40 PF12894.2 EIM79566.1 - 0.057 12.9 0.0 52 3.4 0.0 3.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AcetylCoA_hyd_C PF13336.1 EIM79566.1 - 0.093 12.3 0.0 20 4.8 0.0 2.9 2 1 1 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain Me-amine-dh_H PF06433.6 EIM79566.1 - 0.15 10.6 0.0 2.5 6.6 0.0 2.8 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.10 EIM79566.1 - 0.18 10.3 5.3 13 4.2 0.0 5.3 4 1 4 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1518 PF07469.7 EIM79568.1 - 0.31 11.2 5.0 0.13 12.4 1.3 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF1518) WD40 PF00400.27 EIM79569.1 - 4e-140 451.2 62.7 4.1e-13 48.6 0.1 13.7 13 0 0 13 13 13 12 WD domain, G-beta repeat DUF2235 PF09994.4 EIM79569.1 - 2.8e-50 171.2 4.4 2.1e-40 138.8 0.1 2.7 3 0 0 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) eIF2A PF08662.6 EIM79569.1 - 4.9e-09 36.1 0.0 0.019 14.6 0.0 4.4 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIM79569.1 - 5.7e-06 25.9 7.3 0.5 9.7 0.0 4.5 2 1 0 4 4 4 2 PQQ-like domain PD40 PF07676.7 EIM79569.1 - 0.0025 17.4 21.2 8 6.2 0.1 9.4 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat MogR_DNAbind PF12181.3 EIM79569.1 - 0.03 14.0 0.2 13 5.5 0.0 2.7 2 1 1 3 3 3 0 DNA binding domain of the motility gene repressor (MogR) PQQ_3 PF13570.1 EIM79569.1 - 0.036 14.3 10.5 32 4.9 0.1 6.7 6 1 1 7 7 7 0 PQQ-like domain HPS3_N PF14761.1 EIM79569.1 - 0.23 10.8 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 DUF2235 PF09994.4 EIM79573.1 - 2.8e-46 158.1 0.4 4.9e-46 157.3 0.3 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MogR_DNAbind PF12181.3 EIM79573.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) WD40 PF00400.27 EIM79574.1 - 2.9e-146 470.7 51.0 1.8e-14 52.9 1.4 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat Nup160 PF11715.3 EIM79574.1 - 5e-16 57.9 15.7 0.023 12.8 0.0 9.0 1 1 6 9 9 9 6 Nucleoporin Nup120/160 eIF2A PF08662.6 EIM79574.1 - 1.5e-10 41.1 0.0 0.015 15.0 0.0 5.1 2 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIM79574.1 - 3.6e-10 39.1 13.0 0.039 12.7 0.1 7.3 1 1 4 6 6 6 4 Nup133 N terminal like PD40 PF07676.7 EIM79574.1 - 1.2e-09 37.6 13.6 3.5 7.3 0.0 9.0 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIM79574.1 - 5e-07 29.4 14.6 0.0038 16.7 2.4 4.4 1 1 1 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EIM79574.1 - 1.4e-06 26.9 3.3 0.0033 15.7 0.0 4.5 2 1 4 7 7 7 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIM79574.1 - 4.9e-05 23.4 21.3 0.53 10.6 0.1 8.4 7 2 2 9 9 9 2 PQQ-like domain Nbas_N PF15492.1 EIM79574.1 - 0.00019 20.6 12.1 15 4.5 0.0 7.9 4 2 4 9 9 9 0 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.16 EIM79574.1 - 0.00035 19.9 3.7 18 5.1 0.0 6.4 7 0 0 7 7 7 0 PQQ enzyme repeat Hira PF07569.6 EIM79574.1 - 0.00077 18.7 0.1 1.9 7.6 0.0 4.2 4 3 1 5 5 5 1 TUP1-like enhancer of split DUF3312 PF11768.3 EIM79574.1 - 0.00092 17.5 0.0 12 4.0 0.0 4.8 2 2 2 6 6 6 0 Protein of unknown function (DUF3312) Me-amine-dh_H PF06433.6 EIM79574.1 - 0.014 14.0 0.0 0.65 8.5 0.0 2.9 2 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) GSDH PF07995.6 EIM79574.1 - 0.02 13.9 0.0 4.3 6.3 0.0 3.8 3 2 0 3 3 3 0 Glucose / Sorbosone dehydrogenase IKI3 PF04762.7 EIM79574.1 - 0.03 12.1 0.3 14 3.3 0.1 3.4 2 2 0 4 4 4 0 IKI3 family Robl_LC7 PF03259.12 EIM79574.1 - 0.033 13.7 0.3 0.43 10.1 0.1 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain Apc4_WD40 PF12894.2 EIM79574.1 - 0.061 12.8 0.0 22 4.6 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.1 EIM79574.1 - 0.078 12.3 0.0 8.7 5.6 0.0 2.6 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Tox-PL PF15644.1 EIM79574.1 - 0.1 13.3 1.0 5.3 7.8 0.0 4.0 5 1 0 5 5 5 0 Papain fold toxin 1 PS_Dcarbxylase PF02666.10 EIM79578.1 - 1.7e-34 118.9 0.0 2.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EIM79578.1 - 1.2e-29 102.6 0.0 2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase p450 PF00067.17 EIM79579.1 - 1.3e-64 218.4 0.0 6.2e-64 216.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PS_Dcarbxylase PF02666.10 EIM79582.1 - 1.5e-39 135.4 0.0 2.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EIM79582.1 - 9.4e-36 122.5 0.0 1.6e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase eRF1_1 PF03463.10 EIM79582.1 - 0.14 11.7 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 eRF1 domain 1 UbiA PF01040.13 EIM79583.1 - 6.4e-25 87.8 8.7 7.7e-25 87.5 6.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Pro-NT_NN PF07421.6 EIM79583.1 - 0.19 11.2 0.3 0.97 8.9 0.0 2.2 3 0 0 3 3 3 0 Neurotensin/neuromedin N precursor DUF3444 PF11926.3 EIM79584.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) DUF913 PF06025.7 EIM79585.1 - 0.025 13.3 0.1 0.043 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4218 PF13960.1 EIM79587.1 - 0.025 14.0 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) p450 PF00067.17 EIM79589.1 - 8.8e-63 212.4 0.0 8.1e-62 209.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 HobA PF12163.3 EIM79589.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA replication regulator GMC_oxred_N PF00732.14 EIM79590.1 - 2.5e-60 204.1 0.0 4.1e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM79590.1 - 4.5e-30 104.8 0.0 7.9e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM79590.1 - 0.00012 21.0 0.1 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM79590.1 - 0.029 14.3 0.1 0.081 12.9 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM79590.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM79590.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EIM79590.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIM79590.1 - 0.14 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 EIM79592.1 - 5.1e-29 101.0 61.0 6.4e-23 81.0 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79592.1 - 0.00045 18.9 9.2 0.00045 18.9 6.4 3.8 1 1 3 4 4 4 3 Sugar (and other) transporter Abhydrolase_6 PF12697.2 EIM79594.1 - 2.6e-15 56.9 0.0 3.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM79594.1 - 2e-11 43.8 0.2 7.2e-11 42.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM79594.1 - 4.4e-08 32.5 0.0 8e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EIM79594.1 - 3.2e-07 30.0 0.0 4.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EIM79594.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIM79594.1 - 0.0037 16.8 0.0 0.14 11.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EIM79594.1 - 0.033 13.7 0.1 0.086 12.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EIM79594.1 - 0.15 11.3 0.0 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Tri3 PF07428.6 EIM79595.1 - 2.5e-10 39.6 0.0 2.4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Condensation PF00668.15 EIM79595.1 - 0.049 12.4 0.0 0.17 10.6 0.0 1.7 1 1 0 1 1 1 0 Condensation domain ketoacyl-synt PF00109.21 EIM79596.1 - 3e-48 164.4 0.1 4.4e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EIM79596.1 - 3.5e-27 94.6 0.6 1.7e-26 92.3 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EIM79596.1 - 0.11 11.4 0.1 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Tub_2 PF04525.7 EIM79597.1 - 9.3e-22 77.3 0.0 1.1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Oxidored_FMN PF00724.15 EIM79598.1 - 2e-98 329.5 0.0 2.3e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIM79599.1 - 1.4e-98 330.0 0.0 1.8e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DDE_3 PF13358.1 EIM79604.1 - 6e-09 35.7 0.1 7.8e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIM79605.1 - 0.00095 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIM79605.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIM79605.1 - 0.0024 17.9 0.0 0.0039 17.3 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 EIM79605.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_38 PF13936.1 EIM79605.1 - 0.054 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIM79605.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase UBX PF00789.15 EIM79606.1 - 1.1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain OKR_DC_1_N PF03709.10 EIM79606.1 - 0.039 14.0 0.2 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF2681 PF10883.3 EIM79606.1 - 2.2 8.5 6.6 5.2 7.3 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EF-hand_7 PF13499.1 EIM79607.1 - 9.8e-14 51.2 0.0 9.4e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EIM79607.1 - 2e-12 45.8 0.3 3.8e-05 23.2 0.1 3.0 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EIM79607.1 - 2.1e-11 42.2 0.3 0.00032 19.8 0.0 3.8 3 1 1 4 4 4 2 EF hand EF-hand_8 PF13833.1 EIM79607.1 - 6.8e-08 32.0 0.1 4.3e-05 23.0 0.0 3.4 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 EIM79607.1 - 8.5e-07 28.7 0.0 0.0026 17.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EIM79607.1 - 0.00018 21.0 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EIM79607.1 - 0.0048 16.1 0.9 1.2 8.5 0.1 2.8 2 1 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.5 EIM79607.1 - 0.0052 16.7 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Sigma70_r3 PF04539.11 EIM79607.1 - 0.073 12.9 0.3 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 DUF221 PF02714.10 EIM79609.1 - 3.5e-102 341.6 23.5 6.5e-102 340.7 16.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIM79609.1 - 9.1e-38 129.2 1.3 4.1e-37 127.1 0.9 2.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIM79609.1 - 1.8e-13 50.7 0.0 3.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EIM79609.1 - 0.028 14.3 0.1 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lectin_N PF03954.9 EIM79609.1 - 0.21 10.9 0.1 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain adh_short PF00106.20 EIM79610.1 - 8.6e-22 77.8 0.1 2.4e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM79610.1 - 4.9e-09 36.0 0.0 8.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM79610.1 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EIM79610.1 - 0.00064 19.5 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM79610.1 - 0.00071 19.6 0.1 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIM79610.1 - 0.00073 18.5 0.1 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EIM79610.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FluMu_gp41 PF10109.4 EIM79610.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 NmrA PF05368.8 EIM79610.1 - 0.096 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EIM79610.1 - 0.099 12.4 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GMC_oxred_C PF05199.8 EIM79611.1 - 3.3e-29 102.0 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase AAA_22 PF13401.1 EIM79612.1 - 3.5e-05 23.9 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM79612.1 - 0.0064 16.2 0.6 0.034 13.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF853 PF05872.7 EIM79612.1 - 0.027 12.8 0.0 0.045 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.4 EIM79612.1 - 0.28 9.7 0.0 0.67 8.5 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Peptidase_C48 PF02902.14 EIM79613.1 - 4.3e-08 33.0 0.0 8.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HMG_box_2 PF09011.5 EIM79614.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 HMG-box domain GMC_oxred_N PF00732.14 EIM79618.1 - 2.8e-19 69.3 0.1 3.9e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIM79619.1 - 0.00019 20.7 0.0 0.00019 20.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Drf_FH3 PF06367.11 EIM79619.1 - 0.026 13.9 0.0 0.028 13.8 0.0 1.0 1 0 0 1 1 1 0 Diaphanous FH3 Domain RF-1 PF00472.15 EIM79620.1 - 2.4e-37 127.2 4.4 4.1e-37 126.4 3.0 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EIM79620.1 - 2.2e-27 95.0 0.1 6.6e-27 93.5 0.0 1.8 2 0 0 2 2 2 1 PCRF domain BING4CT PF08149.6 EIM79621.1 - 7e-34 115.1 0.0 8.4e-33 111.7 0.0 2.5 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EIM79621.1 - 1.9e-07 30.7 0.5 1.6e-05 24.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat YL1 PF05764.8 EIM79621.1 - 0.0069 16.0 8.9 0.0069 16.0 6.2 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Glyoxal_oxid_N PF07250.6 EIM79622.1 - 5.6e-33 114.0 0.0 1.4e-30 106.1 0.0 3.5 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM79622.1 - 4.7e-19 68.3 0.1 8.6e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 EIM79622.1 - 0.0038 15.5 0.0 0.0064 14.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 EIM79622.1 - 1.1 9.0 13.5 3.7 7.3 0.1 5.6 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF2396 PF09654.5 EIM79625.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Rad17 PF03215.10 EIM79628.1 - 5.7e-49 167.1 0.0 9.7e-23 80.6 0.0 3.6 3 1 0 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EIM79628.1 - 1.4e-05 25.8 0.0 4.7e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIM79628.1 - 9.9e-05 22.0 0.0 0.00038 20.1 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 EIM79628.1 - 0.00037 20.5 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EIM79628.1 - 0.00074 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM79628.1 - 0.00076 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM79628.1 - 0.003 17.4 0.0 0.02 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EIM79628.1 - 0.0034 17.5 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIM79628.1 - 0.0047 15.8 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EIM79628.1 - 0.0065 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM79628.1 - 0.03 13.4 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EIM79628.1 - 0.032 14.5 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EIM79628.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM79628.1 - 0.043 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EIM79628.1 - 0.084 12.4 0.0 0.34 10.4 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EIM79628.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIM79628.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 EIM79628.1 - 0.21 10.2 0.0 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.7 EIM79628.1 - 0.38 9.9 0.4 0.83 8.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Adeno_E3_14_5 PF04834.7 EIM79629.1 - 0.12 12.7 0.3 0.27 11.6 0.2 1.6 1 0 0 1 1 1 0 Early E3 14.5 kDa protein DSS1_SEM1 PF05160.8 EIM79630.1 - 1.5e-20 72.7 12.5 3.8e-20 71.4 8.7 1.7 1 1 0 1 1 1 1 DSS1/SEM1 family Alpha-amylase PF00128.19 EIM79632.1 - 1e-22 80.9 0.0 2.4e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3239 PF11580.3 EIM79632.1 - 0.019 14.9 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3239) Glyco_hydro_114 PF03537.8 EIM79632.1 - 0.029 14.1 0.5 5.2 6.9 0.0 3.7 3 1 1 4 4 4 0 Glycoside-hydrolase family GH114 Pkinase PF00069.20 EIM79635.1 - 2e-12 46.8 0.0 3.1e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM79635.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3102 PF11300.3 EIM79635.1 - 0.065 13.2 0.3 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) HpcH_HpaI PF03328.9 EIM79636.1 - 4.8e-39 133.5 0.0 5.9e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF1020 PF06255.8 EIM79636.1 - 0.022 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) Rad17 PF03215.10 EIM79637.1 - 6.5e-49 166.9 0.0 4.4e-23 81.7 0.0 4.2 4 0 0 4 4 4 4 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EIM79637.1 - 2.7e-05 24.9 0.0 7.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM79637.1 - 8.8e-05 22.1 0.0 8.8e-05 22.1 0.0 2.9 4 0 0 4 4 3 1 Part of AAA domain AAA_16 PF13191.1 EIM79637.1 - 0.0004 20.4 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EIM79637.1 - 0.00044 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM79637.1 - 0.00086 19.4 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIM79637.1 - 0.0049 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIM79637.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EIM79637.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM79637.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM79637.1 - 0.031 13.3 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EIM79637.1 - 0.032 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EIM79637.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EIM79637.1 - 0.049 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIM79637.1 - 0.17 11.7 0.4 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EIM79637.1 - 0.22 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 EIM79637.1 - 0.24 10.0 0.0 0.24 10.0 0.0 2.2 3 0 0 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EIM79637.1 - 0.36 10.0 0.1 0.89 8.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein 3-HAO PF06052.7 EIM79641.1 - 2.1e-53 179.7 0.0 2.4e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase ThiF PF00899.16 EIM79642.1 - 9.7e-39 132.3 0.0 1.6e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EIM79642.1 - 1.2e-27 95.2 0.0 2.5e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIM79642.1 - 2.6e-20 71.4 1.2 7.2e-20 70.1 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EIM79642.1 - 2.3e-06 27.5 0.0 5.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EIM79642.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_71 PF03659.9 EIM79643.1 - 7.1e-86 288.0 10.0 8.3e-86 287.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 AAA_25 PF13481.1 EIM79645.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM79645.1 - 0.11 12.6 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIM79645.1 - 0.11 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 KaiC COX5A PF02284.11 EIM79645.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Sigma70_ner PF04546.8 EIM79645.1 - 0.52 9.9 4.2 1.1 8.8 2.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EIM79645.1 - 0.77 7.5 5.4 1.1 7.1 3.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EIM79645.1 - 6.1 5.2 6.2 9.4 4.5 4.3 1.1 1 0 0 1 1 1 0 Daxx Family Cu-oxidase PF00394.17 EIM79648.1 - 1.2e-45 155.2 0.5 6.1e-43 146.4 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM79648.1 - 5.8e-36 122.7 1.4 2.6e-34 117.4 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM79648.1 - 4e-35 120.3 3.5 7.8e-31 106.4 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase adh_short PF00106.20 EIM79649.1 - 1.4e-07 31.6 0.3 2.3e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Neuropeptide_S PF14993.1 EIM79649.1 - 0.007 16.0 0.1 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 Neuropeptide S precursor protein VHS PF00790.14 EIM79650.1 - 7.6e-39 132.5 0.0 1e-37 128.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EIM79650.1 - 1.6e-17 63.3 0.1 4.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 GAT domain Abhydrolase_6 PF12697.2 EIM79651.1 - 2.1e-20 73.6 0.1 4.7e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM79651.1 - 0.0039 16.9 0.0 0.029 14.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 EIM79653.1 - 6.4e-63 212.5 0.1 1.4e-30 106.0 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EIM79653.1 - 3.3e-12 47.1 0.0 6.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.19 EIM79654.1 - 6.8e-18 65.2 1.2 6.8e-18 65.2 0.8 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EIM79654.1 - 4e-06 27.1 1.1 8e-06 26.1 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIM79654.1 - 7e-05 22.2 0.0 0.00044 19.7 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIM79654.1 - 0.001 19.6 0.0 0.0051 17.3 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.17 EIM79655.1 - 1.8e-59 201.5 0.0 1e-58 198.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 EIM79657.1 - 2.3e-40 138.1 0.8 3.3e-40 137.6 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FlxA PF14282.1 EIM79658.1 - 0.029 14.3 3.2 0.029 14.3 2.2 1.7 1 1 0 1 1 1 0 FlxA-like protein Phage_GP20 PF06810.6 EIM79658.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 FliD_N PF02465.13 EIM79658.1 - 0.48 10.8 12.5 0.8 10.1 4.1 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CAP_N PF01213.14 EIM79660.1 - 0.87 8.8 5.0 1.4 8.0 3.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.20 EIM79661.1 - 1.2e-18 67.5 0.0 2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EIM79661.1 - 1.7e-06 27.6 0.0 5.9e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM79661.1 - 6.1e-06 26.0 0.0 8.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM79661.1 - 8.5e-06 25.7 0.2 2.2e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM79661.1 - 0.00019 21.4 0.4 0.0014 18.6 0.1 2.0 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM79661.1 - 0.0012 17.8 0.0 0.0023 16.8 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM79661.1 - 0.047 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1029 PF06269.7 EIM79661.1 - 1.1 9.3 3.5 4.3 7.4 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1029) Abhydrolase_5 PF12695.2 EIM79663.1 - 5.1e-21 74.9 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM79663.1 - 1.8e-17 63.9 0.0 1.5e-15 57.7 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM79663.1 - 3.5e-06 26.7 0.0 2.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIM79663.1 - 0.0019 17.9 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EIM79663.1 - 0.002 17.5 0.1 4 6.8 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 EIM79663.1 - 0.0036 16.5 0.0 0.62 9.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EIM79663.1 - 0.0086 15.3 0.0 0.046 12.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EIM79663.1 - 0.017 14.5 0.0 0.15 11.4 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase (FSH1) AXE1 PF05448.7 EIM79663.1 - 0.048 12.1 0.4 0.76 8.2 0.0 2.0 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EIM79663.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 EIM79663.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4337 PF14235.1 EIM79665.1 - 0.27 11.0 1.5 0.46 10.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Rad17 PF03215.10 EIM79666.1 - 3.9e-24 85.2 1.2 6.2e-18 64.7 0.4 3.1 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EIM79666.1 - 9.4e-06 26.4 0.0 7.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM79666.1 - 8e-05 22.3 0.1 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM79666.1 - 0.00061 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM79666.1 - 0.00065 20.0 0.2 0.0018 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 EIM79666.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIM79666.1 - 0.0018 18.1 0.1 0.015 15.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EIM79666.1 - 0.0025 16.7 0.1 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EIM79666.1 - 0.0037 17.2 0.1 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EIM79666.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIM79666.1 - 0.013 15.7 0.1 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EIM79666.1 - 0.018 14.9 0.1 0.039 13.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EIM79666.1 - 0.02 14.5 0.2 0.044 13.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Herpes_Helicase PF02689.9 EIM79666.1 - 0.025 12.3 0.0 0.034 11.8 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.1 EIM79666.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIM79666.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EIM79666.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EIM79666.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIM79666.1 - 0.18 11.5 0.1 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EIM79666.1 - 0.26 10.7 0.2 0.42 10.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIM79667.1 - 0.00019 21.5 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM79667.1 - 0.012 15.3 0.8 0.05 13.3 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain DUF853 PF05872.7 EIM79667.1 - 0.035 12.4 0.0 0.065 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NACHT PF05729.7 EIM79669.1 - 2.9e-08 33.5 0.0 6.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain CHAT PF12770.2 EIM79669.1 - 1e-07 31.3 0.5 2.4e-07 30.1 0.3 1.6 1 0 0 1 1 1 1 CHAT domain AAA_25 PF13481.1 EIM79669.1 - 2.4e-06 27.0 0.0 2.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM79669.1 - 8.6e-05 22.6 0.7 0.0011 19.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIM79669.1 - 0.00016 21.7 0.5 0.00016 21.7 0.4 4.4 4 1 0 4 4 4 1 AAA ATPase domain NB-ARC PF00931.17 EIM79669.1 - 0.02 13.7 0.0 0.046 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EIM79669.1 - 0.069 13.3 0.9 0.78 9.9 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIM79669.1 - 0.077 12.7 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Atg14 PF10186.4 EIM79669.1 - 0.75 8.6 14.4 2 7.2 10.0 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FTCD_C PF04961.7 EIM79669.1 - 2.6 7.4 5.9 6.9 6.0 3.9 1.8 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase APG6 PF04111.7 EIM79669.1 - 4.4 6.2 8.9 7.9 5.4 6.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Tet_JBP PF12851.2 EIM79670.1 - 4.2e-08 32.6 0.0 5.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily COX5A PF02284.11 EIM79672.1 - 0.0095 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va AAA_29 PF13555.1 EIM79672.1 - 0.15 11.6 0.1 0.4 10.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.11 EIM79674.1 - 1.1e-13 50.7 20.5 1.4e-13 50.3 14.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TF_Zn_Ribbon PF08271.7 EIM79675.1 - 0.24 10.7 1.4 0.53 9.6 0.6 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_4 PF13894.1 EIM79675.1 - 6.2 7.4 22.7 0.39 11.1 2.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger UQ_con PF00179.21 EIM79676.1 - 2e-47 160.1 0.0 2.3e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM79676.1 - 8.7e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIM79676.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EIM79676.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 RWD domain Skp1_POZ PF03931.10 EIM79677.1 - 6.5e-08 32.5 0.0 9.7e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Glyco_hydro_71 PF03659.9 EIM79679.1 - 3.1e-96 322.1 17.0 3.6e-96 321.9 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF2714 PF10896.3 EIM79679.1 - 0.11 12.2 0.3 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) CutC PF03932.9 EIM79679.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 CutC family zf-RING_2 PF13639.1 EIM79681.1 - 9.9e-08 31.6 4.4 1.6e-07 31.0 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM79681.1 - 0.00033 20.6 0.9 0.00047 20.1 0.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIM79681.1 - 0.0018 17.9 3.2 0.0026 17.4 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM79681.1 - 0.0082 15.7 2.6 0.014 15.0 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIM79681.1 - 0.0087 15.7 3.4 0.015 14.9 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EIM79681.1 - 0.011 15.7 4.5 0.021 14.8 3.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM79681.1 - 0.028 14.1 2.1 0.052 13.2 1.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EIM79681.1 - 0.077 13.0 0.5 0.092 12.7 0.3 1.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-Apc11 PF12861.2 EIM79681.1 - 0.14 12.0 3.4 0.53 10.1 2.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EIM79681.1 - 0.99 9.1 4.4 1.8 8.3 3.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EIM79681.1 - 1.8 8.6 5.4 4.6 7.3 0.7 2.3 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.2 EIM79681.1 - 4.7 7.3 7.5 14 5.8 0.2 2.2 1 1 1 2 2 2 0 RING-variant domain Saccharop_dh PF03435.13 EIM79682.1 - 1.4e-22 80.2 0.0 1.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase YbbR PF07949.7 EIM79683.1 - 0.057 13.5 0.8 0.057 13.5 0.6 2.3 2 1 0 2 2 2 0 YbbR-like protein CAF-1_p150 PF11600.3 EIM79684.1 - 0.00043 19.7 4.7 0.00043 19.7 3.3 2.6 2 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal NADH_4Fe-4S PF10589.4 EIM79688.1 - 0.06 12.5 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sigma70_ner PF04546.8 EIM79690.1 - 0.64 9.6 3.9 1.5 8.3 2.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region BNIP2 PF12496.3 EIM79690.1 - 0.79 9.9 8.4 1.7 8.8 5.8 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Daxx PF03344.10 EIM79690.1 - 6.6 5.0 5.3 9.8 4.5 3.7 1.1 1 0 0 1 1 1 0 Daxx Family Tet_JBP PF12851.2 EIM79692.1 - 7.3e-07 28.6 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Baculo_PEP_C PF04513.7 EIM79693.1 - 0.0006 19.6 1.6 0.00092 19.0 1.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.3 EIM79693.1 - 0.21 11.4 2.6 0.48 10.2 0.4 2.2 1 1 0 2 2 2 0 Hydrophobic surface binding protein A Ifi-6-16 PF06140.8 EIM79694.1 - 0.075 12.8 3.7 3.6 7.4 0.1 2.7 2 0 0 2 2 2 0 Interferon-induced 6-16 family Transgly_assoc PF04226.8 EIM79694.1 - 1.6 8.8 8.0 2.9 8.0 0.5 3.2 3 0 0 3 3 3 0 Transglycosylase associated protein BRI3BP PF14965.1 EIM79696.1 - 0.087 12.1 1.1 0.19 11.0 0.7 1.7 1 1 0 1 1 1 0 Negative regulator of p53/TP53 DUF3437 PF11919.3 EIM79696.1 - 0.4 10.4 1.8 2.5 7.8 1.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3437) SSF PF00474.12 EIM79698.1 - 2.9e-21 75.5 34.1 5.4e-21 74.7 23.6 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family F-box-like PF12937.2 EIM79699.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 EIM79702.1 - 0.00028 20.4 1.3 0.00053 19.5 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM79702.1 - 0.0024 17.5 0.8 0.0049 16.5 0.5 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIM79703.1 - 1.9e-19 68.7 15.8 2.5e-06 27.1 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 EIM79703.1 - 0.001 18.6 0.2 0.38 10.4 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIM79703.1 - 0.0035 16.1 0.1 0.0069 15.1 0.0 1.7 1 1 0 1 1 1 1 Nup133 N terminal like DUF3261 PF11659.3 EIM79703.1 - 0.012 15.1 0.0 2.8 7.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3261) Nbas_N PF15492.1 EIM79703.1 - 0.02 14.0 1.0 1.4 7.9 0.0 2.8 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EIM79703.1 - 0.051 12.9 0.4 5.8 6.2 0.0 2.6 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 EIM79704.1 - 7.1e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 NACHT domain CbiA PF01656.18 EIM79704.1 - 0.0035 16.7 0.4 0.0049 16.2 0.2 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EIM79704.1 - 0.0065 16.7 0.0 0.0084 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIM79704.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM79704.1 - 0.017 15.9 0.1 0.02 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM79704.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EIM79704.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.15 EIM79704.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 EIM79704.1 - 0.039 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EIM79704.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EIM79704.1 - 0.085 11.6 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EIM79704.1 - 0.085 11.8 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EIM79704.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EIM79704.1 - 0.11 11.8 0.1 7 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain HHH_2 PF12826.2 EIM79704.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.1 EIM79704.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.17 EIM79706.1 - 2.7e-14 53.4 0.0 7.7e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Caspase domain PsaM PF07465.8 EIM79707.1 - 0.19 11.3 3.7 0.5 9.9 2.5 1.7 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) zf-C2H2_4 PF13894.1 EIM79710.1 - 2.4e-10 40.0 44.5 0.0012 19.0 0.1 7.3 5 2 2 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIM79710.1 - 3.8e-10 39.5 42.6 0.076 13.1 1.9 7.5 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EIM79710.1 - 2e-06 27.7 46.1 0.057 13.7 2.3 7.6 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIM79710.1 - 2.5e-06 27.5 37.2 0.026 14.6 0.3 6.8 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EIM79710.1 - 0.00018 21.2 37.4 0.2 11.6 2.5 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger Zn_ribbon_2 PF12674.2 EIM79710.1 - 0.0012 19.1 8.5 0.058 13.7 0.7 3.0 3 0 0 3 3 3 2 Putative zinc ribbon domain Rad50_zn_hook PF04423.9 EIM79710.1 - 0.0035 16.7 6.2 7.3 6.1 0.0 5.3 4 1 1 5 5 5 1 Rad50 zinc hook motif zf-met PF12874.2 EIM79710.1 - 0.024 14.8 41.0 0.87 9.8 0.1 7.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.1 EIM79710.1 - 0.86 9.3 0.1 0.86 9.3 0.1 5.4 7 0 0 7 7 7 0 zinc-ribbon domain DZR PF12773.2 EIM79710.1 - 1.8 8.4 23.2 3.3 7.5 0.1 4.8 3 1 1 4 4 4 0 Double zinc ribbon zf-C2HC_2 PF13913.1 EIM79710.1 - 2.1 8.1 22.7 1.2 8.8 0.1 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EIM79710.1 - 6.3 7.2 39.0 0.96 9.8 2.9 6.6 6 1 0 6 6 6 0 Zinc-finger double domain SnoaL PF07366.7 EIM79711.1 - 9.7e-07 28.4 0.1 1.4e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EIM79711.1 - 0.00017 21.9 0.1 0.00028 21.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.9 EIM79712.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIM79712.1 - 0.05 12.7 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain FAD_binding_3 PF01494.14 EIM79714.1 - 1.8e-06 27.2 0.0 0.0067 15.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tub_2 PF04525.7 EIM79716.1 - 0.039 13.3 0.0 0.046 13.1 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 WD40 PF00400.27 EIM79717.1 - 2.8e-17 61.8 11.3 4.4e-05 23.1 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM79717.1 - 0.00084 18.2 0.0 0.00096 17.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like PD40 PF07676.7 EIM79717.1 - 0.0075 15.9 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIM79717.1 - 0.043 12.9 0.4 3 6.8 0.0 2.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.7 EIM79718.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NACHT PF05729.7 EIM79719.1 - 0.012 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.18 EIM79719.1 - 0.019 14.4 0.3 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.17 EIM79719.1 - 0.019 13.8 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EIM79719.1 - 0.04 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TruD PF01142.13 EIM79719.1 - 0.042 12.5 0.1 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) AAA_18 PF13238.1 EIM79719.1 - 0.065 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM79719.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 EIM79719.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EIM79719.1 - 0.089 13.6 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM79719.1 - 0.092 12.7 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EIM79719.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.10 EIM79719.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase Methyltransf_2 PF00891.13 EIM79720.1 - 1.6e-13 50.4 0.3 7.9e-11 41.5 0.0 2.7 2 1 0 2 2 2 2 O-methyltransferase MFS_1 PF07690.11 EIM79721.1 - 3.8e-30 104.7 18.5 3.8e-30 104.7 12.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79721.1 - 3.2e-10 39.1 16.6 3.4e-05 22.6 3.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 EIM79721.1 - 0.00097 17.7 2.9 0.00097 17.7 2.0 3.9 2 2 1 3 3 3 1 Vacuole effluxer Atg22 like Nuc_H_symport PF03825.11 EIM79721.1 - 0.0017 17.1 6.3 0.025 13.3 4.1 2.4 2 0 0 2 2 2 1 Nucleoside H+ symporter Oxidored_FMN PF00724.15 EIM79722.1 - 7.2e-65 219.2 0.0 1.1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Response_reg PF00072.19 EIM79723.1 - 1.8e-20 72.9 0.7 3.3e-20 72.1 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EIM79723.1 - 5.8e-20 71.0 0.1 1.3e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIM79723.1 - 3.5e-06 26.9 0.1 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 EIM79723.1 - 0.013 15.2 0.1 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AMP-binding PF00501.23 EIM79724.1 - 9.8e-45 152.6 0.0 1.6e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM79724.1 - 2.5e-28 98.6 0.0 5.5e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIM79724.1 - 4.6e-10 39.3 0.0 9.1e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM79724.1 - 0.00017 21.7 0.0 0.00055 20.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EIM79724.1 - 0.00073 18.5 0.1 0.071 11.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 EIM79724.1 - 0.016 14.4 0.2 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 EIM79724.1 - 0.025 14.2 0.0 0.08 12.6 0.0 1.9 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EIM79724.1 - 0.085 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Abhydrolase_1 PF00561.15 EIM79724.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DapB_N PF01113.15 EIM79724.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-MYND PF01753.13 EIM79725.1 - 2.4e-07 30.4 15.0 5e-07 29.4 10.4 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM79725.1 - 2 8.3 6.4 4.2 7.3 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.27 EIM79726.1 - 3.2e-13 48.9 0.0 0.00032 20.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 EIM79726.1 - 4.8e-06 26.1 0.3 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM79726.1 - 5.4e-05 22.7 0.2 0.0008 18.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 EIM79726.1 - 0.0041 16.6 0.1 0.23 10.8 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain Elongin_A PF06881.6 EIM79726.1 - 0.027 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A AMP-binding PF00501.23 EIM79727.1 - 1.1e-84 284.2 0.0 1.4e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM79727.1 - 3.1e-15 56.8 0.1 1.6e-14 54.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF972 PF06156.8 EIM79729.1 - 6.9 7.0 8.4 1.1 9.6 2.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TACC PF05010.9 EIM79731.1 - 0.00082 19.1 2.7 0.0015 18.3 1.8 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) IncA PF04156.9 EIM79731.1 - 0.0058 16.2 5.7 0.0097 15.5 3.9 1.3 1 0 0 1 1 1 1 IncA protein Orbi_VP5 PF00901.12 EIM79731.1 - 0.13 10.4 5.7 0.28 9.3 4.0 1.5 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 ERM PF00769.14 EIM79731.1 - 0.23 10.9 12.6 0.44 10.0 8.8 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.4 EIM79731.1 - 6.4 4.9 20.1 25 2.9 13.9 1.9 1 1 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 EIM79734.1 - 2 7.9 8.0 0.49 9.9 0.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EIM79734.1 - 3 7.5 9.6 0.88 9.3 3.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Curto_V3 PF07436.6 EIM79737.1 - 0.11 12.5 1.1 22 5.2 0.1 3.1 2 1 1 3 3 3 0 Curtovirus V3 protein GMC_oxred_N PF00732.14 EIM79738.1 - 1.1e-56 192.2 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM79738.1 - 6.8e-38 130.2 0.0 1.2e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM79738.1 - 6.1e-05 22.0 1.0 0.0026 16.7 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM79738.1 - 0.00015 20.8 1.4 0.037 12.8 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM79738.1 - 0.00024 21.0 0.1 0.0006 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM79738.1 - 0.00035 19.6 0.2 0.00052 19.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM79738.1 - 0.0026 17.8 0.7 0.083 12.9 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79738.1 - 0.018 13.5 0.5 0.84 8.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EIM79738.1 - 0.021 14.7 0.1 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM79738.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PALP PF00291.20 EIM79738.1 - 0.1 11.8 0.4 0.23 10.6 0.2 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Cauli_VI PF01693.11 EIM79740.1 - 7.1e-14 51.5 0.3 6.5e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin zf-B_box PF00643.19 EIM79741.1 - 1.2 9.0 6.3 3.1 7.7 4.3 1.7 1 0 0 1 1 1 0 B-box zinc finger DDE_3 PF13358.1 EIM79742.1 - 1.3e-08 34.6 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Helicase_C PF00271.26 EIM79742.1 - 0.011 15.5 0.0 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain RHH_1 PF01402.16 EIM79742.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family rve PF00665.21 EIM79743.1 - 8e-12 45.3 0.0 9.7e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIM79743.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain HEAT PF02985.17 EIM79749.1 - 1.4e-10 40.2 7.8 3.6e-06 26.5 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EIM79749.1 - 1.6e-09 38.0 0.0 0.00013 22.2 0.0 4.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIM79749.1 - 7.2e-09 35.8 6.4 0.0016 18.8 0.0 7.0 5 2 2 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 EIM79749.1 - 9.7e-08 32.1 0.3 3.3e-05 24.0 0.0 3.7 3 1 0 3 3 3 1 HEAT repeats RIX1 PF08167.7 EIM79749.1 - 2.1e-06 27.4 0.0 0.00028 20.6 0.0 3.6 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EIM79749.1 - 0.0022 16.7 2.9 0.0037 16.0 0.0 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 EIM79749.1 - 0.025 14.5 0.0 37 4.2 0.0 3.7 3 1 0 4 4 4 0 Domain of unknown function (DUF3385) Nic96 PF04097.9 EIM79752.1 - 2.5e-05 22.6 0.0 2.5e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 SAM_2 PF07647.12 EIM79753.1 - 1.4e-11 44.0 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIM79753.1 - 9.1e-09 35.3 0.3 1.9e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 EIM79753.1 - 1.3e-06 28.5 0.7 7e-06 26.1 0.5 2.2 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.23 EIM79753.1 - 0.0015 17.8 0.2 0.0034 16.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 EIM79753.1 - 0.0027 17.9 0.7 0.0093 16.2 0.5 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 EIM79753.1 - 0.0078 16.2 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SH3_9 PF14604.1 EIM79753.1 - 0.0097 15.4 0.1 0.032 13.8 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain DMPK_coil PF08826.5 EIM79756.1 - 0.0081 16.0 4.7 0.67 9.8 0.4 3.0 2 1 0 2 2 2 2 DMPK coiled coil domain like cwf18 PF08315.7 EIM79756.1 - 0.021 15.2 3.2 0.036 14.5 2.2 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor ERM PF00769.14 EIM79756.1 - 0.026 14.0 5.8 0.038 13.5 4.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 EIM79756.1 - 0.11 12.1 0.2 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II APG6 PF04111.7 EIM79756.1 - 0.12 11.4 3.1 0.18 10.8 2.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EIM79756.1 - 0.21 11.4 8.7 1.9 8.3 1.9 2.0 1 1 1 2 2 2 0 Tropomyosin like Sipho_Gp157 PF05565.6 EIM79756.1 - 0.34 10.4 2.0 0.54 9.8 1.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 M PF02370.11 EIM79756.1 - 0.6 10.6 10.1 0.15 12.4 1.8 3.2 2 1 1 3 3 3 0 M protein repeat TMF_DNA_bd PF12329.3 EIM79756.1 - 0.76 9.6 4.3 5.4 6.8 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.1 EIM79756.1 - 4.1 7.2 11.4 60 3.4 7.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) ABC_tran PF00005.22 EIM79757.1 - 7.5e-07 29.5 0.0 8.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter MFS_1 PF07690.11 EIM79758.1 - 0.021 13.5 2.6 0.025 13.2 1.8 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily zf-XS PF03470.9 EIM79761.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 XS zinc finger domain RNA_lig_T4_1 PF09511.5 EIM79762.1 - 3.1e-21 75.8 0.0 3.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DEAD PF00270.24 EIM79763.1 - 0.0028 17.1 0.0 0.0055 16.2 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1664 PF07889.7 EIM79765.1 - 3.7e-05 23.5 1.7 3.7e-05 23.5 1.1 5.6 4 2 2 6 6 6 2 Protein of unknown function (DUF1664) Filament PF00038.16 EIM79765.1 - 0.48 9.8 64.4 0.16 11.4 5.4 4.6 1 1 3 4 4 4 0 Intermediate filament protein XPC-binding PF09280.6 EIM79766.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 XPC-binding domain WD40 PF00400.27 EIM79768.1 - 3.9e-08 32.8 0.4 0.0077 16.0 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EIM79768.1 - 0.0019 18.3 0.4 0.045 14.0 0.0 2.8 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EIM79768.1 - 0.11 12.0 0.1 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4218 PF13960.1 EIM79771.1 - 0.00092 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TFIIA PF03153.8 EIM79773.1 - 0.0039 17.1 27.9 0.012 15.5 19.3 1.9 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EIM79773.1 - 2.3 6.0 53.7 3.7 5.3 37.2 1.2 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 EIM79773.1 - 3.7 6.9 13.6 6.9 6.0 9.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO JmjC PF02373.17 EIM79778.1 - 1.6e-08 34.8 0.1 7.7e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIM79778.1 - 0.0042 16.6 0.1 0.01 15.3 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EIM79778.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain F-box PF00646.28 EIM79779.1 - 0.00049 19.6 1.4 0.0016 18.0 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM79779.1 - 0.0076 15.9 0.3 0.0076 15.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 EIM79782.1 - 0.0089 15.8 0.1 0.0089 15.8 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Imp-YgjV PF10688.4 EIM79782.1 - 0.052 12.9 1.7 0.13 11.6 1.2 1.7 1 0 0 1 1 1 0 Bacterial inner membrane protein DUF1729 PF08354.5 EIM79784.1 - 6.9e-25 86.6 0.2 1.9e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) DUF3947 PF13135.1 EIM79785.1 - 0.031 14.4 0.3 0.041 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) PspA_IM30 PF04012.7 EIM79785.1 - 0.059 12.7 0.1 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 PspA/IM30 family SnoaL_2 PF12680.2 EIM79786.1 - 9.1e-06 26.0 0.2 1.7e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain PA14 PF07691.7 EIM79787.1 - 0.002 17.8 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 PA14 domain Pox_Ag35 PF03286.9 EIM79788.1 - 3.4 7.1 12.2 3.2 7.2 3.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EIM79788.1 - 4.9 4.9 29.6 2.1 6.1 2.0 2.0 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EIM79788.1 - 5 5.4 22.9 0.21 10.0 7.4 2.0 2 0 0 2 2 2 0 Daxx Family Astro_capsid PF03115.9 EIM79788.1 - 5.3 5.1 6.5 0.37 8.9 0.8 1.7 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 EIM79788.1 - 5.9 6.5 22.0 0.16 11.6 2.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Chromo PF00385.19 EIM79790.1 - 1.2e-07 31.2 0.0 1.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIM79790.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF845 PF05820.6 EIM79790.1 - 0.018 14.7 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) GATA PF00320.22 EIM79791.1 - 4e-20 70.8 15.5 4.5e-14 51.4 2.3 2.4 2 0 0 2 2 2 2 GATA zinc finger zf-RING_3 PF14369.1 EIM79791.1 - 0.0057 16.6 0.9 0.018 15.0 0.6 1.9 1 0 0 1 1 1 1 zinc-finger RRN7 PF11781.3 EIM79791.1 - 0.3 10.6 4.8 0.19 11.2 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EIM79791.1 - 0.45 9.8 9.8 0.07 12.4 2.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EIM79791.1 - 1.3 8.6 4.4 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Pkinase PF00069.20 EIM79792.1 - 0.02 14.0 0.0 0.14 11.3 0.0 2.2 3 0 0 3 3 3 0 Protein kinase domain HEAT PF02985.17 EIM79793.1 - 0.00065 19.5 0.1 19 5.7 0.0 4.4 3 1 1 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EIM79793.1 - 0.0036 17.5 0.3 0.89 9.8 0.0 3.2 3 1 1 4 4 4 2 HEAT repeats Utp12 PF04003.7 EIM79793.1 - 0.063 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Glyco_hydro_18 PF00704.23 EIM79794.1 - 4.7e-51 174.2 2.8 9.5e-51 173.2 1.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.19 EIM79794.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF4185 PF13810.1 EIM79795.1 - 0.0027 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) HALZ PF02183.13 EIM79795.1 - 0.016 14.8 2.6 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper CASP_C PF08172.7 EIM79795.1 - 2.7 6.9 11.0 7.7 5.4 7.6 1.7 1 1 0 1 1 1 0 CASP C terminal DUF904 PF06005.7 EIM79795.1 - 5.9 7.2 7.8 7.1 6.9 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF904 PF06005.7 EIM79796.1 - 0.00063 19.9 2.1 0.0049 17.1 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF904) DUF1875 PF08961.5 EIM79796.1 - 0.03 13.6 0.3 0.058 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) AsnC_trans_reg PF01037.16 EIM79796.1 - 0.18 11.5 0.6 8 6.2 0.0 2.3 2 0 0 2 2 2 0 AsnC family G-alpha PF00503.15 EIM79797.1 - 1.5e-34 119.4 0.0 2.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Ribosomal_L7Ae PF01248.21 EIM79800.1 - 8.4e-14 50.8 0.3 1.4e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APH PF01636.18 EIM79801.1 - 1.7e-17 63.9 1.1 2.2e-17 63.6 0.8 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM79801.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Abhydrolase_6 PF12697.2 EIM79801.1 - 0.014 15.2 0.2 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kdo PF06293.9 EIM79801.1 - 0.093 11.7 0.1 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydantoinase_A PF01968.13 EIM79803.1 - 3.4e-09 36.2 0.2 3.4e-09 36.2 0.2 2.4 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM79803.1 - 4.2e-09 36.1 1.1 9.6e-09 34.9 0.3 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIM79803.1 - 0.026 12.8 3.0 0.62 8.3 1.4 2.7 2 1 0 2 2 2 0 MutL protein Zn_clus PF00172.13 EIM79804.1 - 3.2e-06 26.9 7.1 6.5e-06 25.9 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIM79804.1 - 5.5e-05 22.1 1.6 0.045 12.6 0.1 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain LIN37 PF15306.1 EIM79804.1 - 0.11 12.4 3.1 0.3 11.0 0.3 2.6 2 0 0 2 2 2 0 LIN37 COesterase PF00135.23 EIM79805.1 - 2.4e-11 43.0 0.0 2.9e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Transformer PF06495.6 EIM79807.1 - 0.52 10.1 8.9 1.2 8.9 6.2 1.6 1 1 0 1 1 1 0 Fruit fly transformer protein FAM220 PF15487.1 EIM79807.1 - 1.5 8.1 10.0 1.8 7.8 6.9 1.1 1 0 0 1 1 1 0 FAM220 family UBN2_2 PF14227.1 EIM79809.1 - 6.7e-08 32.1 0.1 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM79809.1 - 0.00022 20.9 0.1 0.00049 19.8 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Protocadherin PF08374.6 EIM79809.1 - 0.44 10.1 7.1 0.74 9.4 4.9 1.3 1 0 0 1 1 1 0 Protocadherin Neur_chan_memb PF02932.11 EIM79809.1 - 0.95 9.2 4.4 1.4 8.7 3.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2201_N PF13203.1 EIM79809.1 - 1.4 8.0 11.4 2.4 7.2 7.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain eIF-3_zeta PF05091.7 EIM79809.1 - 3.1 6.3 10.6 4.4 5.8 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-B_box PF00643.19 EIM79812.1 - 4.5 7.2 12.9 1.5 8.7 6.6 2.0 2 0 0 2 2 2 0 B-box zinc finger Retrotrans_gag PF03732.12 EIM79814.1 - 0.19 11.7 2.4 0.77 9.8 1.6 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein MULE PF10551.4 EIM79815.1 - 9.7e-08 32.0 0.0 1.4e-06 28.3 0.0 2.5 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 EIM79815.1 - 0.0076 15.7 0.8 0.0076 15.7 0.6 2.4 3 0 0 3 3 3 1 SWIM zinc finger GATase_5 PF13507.1 EIM79816.1 - 8.8e-78 260.7 0.0 1.5e-77 260.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EIM79816.1 - 2.3e-42 144.5 1.7 5.5e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIM79816.1 - 1.2e-10 41.4 0.0 6.8e-09 35.8 0.0 3.3 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain Fungal_trans PF04082.13 EIM79818.1 - 2.3e-13 49.6 2.7 3.8e-13 48.9 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM79818.1 - 2.9e-05 23.8 4.6 5.7e-05 22.9 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 EIM79820.1 - 4.1e-07 29.4 0.0 5.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CPT PF07931.7 EIM79822.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_11 PF13414.1 EIM79824.1 - 0.00081 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EIM79824.1 - 0.0042 16.6 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIM79824.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Daxx PF03344.10 EIM79825.1 - 0.19 10.2 30.7 0.29 9.5 21.3 1.2 1 0 0 1 1 1 0 Daxx Family Collagen PF01391.13 EIM79825.1 - 0.5 9.9 10.5 1.2 8.7 7.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PUF PF00806.14 EIM79826.1 - 9.1e-25 84.7 3.1 4.3e-08 32.2 0.1 4.4 3 1 1 4 4 4 4 Pumilio-family RNA binding repeat RasGAP PF00616.14 EIM79827.1 - 8e-40 136.6 0.3 4.4e-39 134.1 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase Mucin PF01456.12 EIM79829.1 - 0.74 9.5 4.3 0.83 9.4 3.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein NmrA PF05368.8 EIM79830.1 - 3.7e-21 75.4 0.0 5.1e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM79830.1 - 1.7e-07 31.4 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding SBP_bac_11 PF13531.1 EIM79830.1 - 0.032 13.8 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein TrkA_N PF02254.13 EIM79830.1 - 0.11 12.4 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EIM79830.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DNA_topoisoIV PF00521.15 EIM79831.1 - 0.0016 17.3 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A ABC_tran PF00005.22 EIM79832.1 - 2.4e-05 24.6 0.0 2.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter APH PF01636.18 EIM79834.1 - 0.0073 16.0 0.6 0.0093 15.7 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM79834.1 - 0.031 13.4 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain DUF3631 PF12307.3 EIM79835.1 - 0.12 12.2 3.9 0.45 10.3 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3631) Cauli_VI PF01693.11 EIM79836.1 - 3.6e-14 52.4 4.8 2.2e-06 27.5 0.0 3.8 3 1 1 4 4 4 3 Caulimovirus viroplasmin PAT1 PF09770.4 EIM79836.1 - 5.8 5.0 6.2 6.8 4.7 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tet_JBP PF12851.2 EIM79838.1 - 1.2e-08 34.4 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM79838.1 - 0.0077 16.7 0.0 0.02 15.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF448 PF04296.8 EIM79842.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) zf-B_box PF00643.19 EIM79842.1 - 3.9 7.4 15.0 2 8.3 8.0 2.4 2 1 0 2 2 2 0 B-box zinc finger SNF2_N PF00176.18 EIM79844.1 - 0.00054 18.8 0.0 0.00068 18.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EIM79844.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.9 EIM79845.1 - 2.2e-11 43.2 0.0 2.3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EIM79848.1 - 9.2e-14 50.9 2.2 1e-13 50.7 1.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79848.1 - 5.6e-11 41.6 1.3 6.6e-11 41.4 0.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIM79848.1 - 0.00081 17.7 0.1 0.0013 16.9 0.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tet_JBP PF12851.2 EIM79850.1 - 2.9e-05 23.4 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily GSK-3_bind PF05350.7 EIM79851.1 - 0.11 11.9 2.3 0.14 11.5 1.6 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DUF605 PF04652.11 EIM79851.1 - 5.5 6.2 8.9 7 5.9 6.2 1.1 1 0 0 1 1 1 0 Vta1 like WXG100 PF06013.7 EIM79852.1 - 0.011 15.7 0.2 0.029 14.3 0.1 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG WEMBL PF05701.6 EIM79852.1 - 0.015 13.7 0.2 0.02 13.3 0.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Seryl_tRNA_N PF02403.17 EIM79852.1 - 0.033 14.1 2.0 0.044 13.8 0.6 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 EIM79852.1 - 0.12 11.5 0.2 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIM79852.1 - 0.14 10.6 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.10 EIM79852.1 - 0.34 11.0 2.0 0.35 11.0 0.2 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TBPIP PF07106.8 EIM79854.1 - 0.016 14.7 0.3 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SseC PF04888.7 EIM79854.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ribonucleas_3_2 PF11469.3 EIM79854.1 - 0.045 13.9 0.2 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease III Occludin_ELL PF07303.8 EIM79854.1 - 0.051 14.2 0.6 0.097 13.4 0.4 1.4 1 0 0 1 1 1 0 Occludin homology domain DUF641 PF04859.7 EIM79854.1 - 0.063 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.1 EIM79854.1 - 0.08 12.3 1.4 0.13 11.6 1.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease APG6 PF04111.7 EIM79854.1 - 0.087 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GPO PF05929.6 EIM79854.1 - 0.097 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF948 PF06103.6 EIM79854.1 - 0.14 12.0 0.4 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EIM79854.1 - 0.14 11.9 2.5 0.2 11.4 0.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ECM11 PF15463.1 EIM79854.1 - 0.18 12.0 1.7 0.4 10.9 1.2 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 Prefoldin_2 PF01920.15 EIM79854.1 - 0.57 9.9 4.2 5.2 6.8 2.3 2.6 2 1 1 3 3 3 0 Prefoldin subunit F-box PF00646.28 EIM79856.1 - 0.048 13.3 0.1 12 5.6 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EIM79856.1 - 0.096 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like DDE_3 PF13358.1 EIM79857.1 - 1.9e-09 37.4 0.0 4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease NR_Repeat PF14046.1 EIM79857.1 - 0.023 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor repeat AHS2 PF02626.10 EIM79859.1 - 1.2e-13 51.0 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 zf-B_box PF00643.19 EIM79861.1 - 0.00026 20.8 7.6 0.00026 20.8 5.2 2.3 2 0 0 2 2 2 1 B-box zinc finger Cauli_VI PF01693.11 EIM79865.1 - 7.9e-11 41.8 0.0 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin DUF605 PF04652.11 EIM79865.1 - 0.031 13.6 11.2 0.036 13.4 7.8 1.1 1 0 0 1 1 1 0 Vta1 like EF-hand_1 PF00036.27 EIM79868.1 - 0.048 12.9 1.8 0.32 10.4 0.1 2.7 2 0 0 2 2 2 0 EF hand F-box-like PF12937.2 EIM79869.1 - 0.00018 21.1 0.7 0.00086 18.9 0.5 2.2 1 1 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EIM79869.1 - 0.012 16.0 0.1 0.091 13.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CAF-1_p150 PF11600.3 EIM79870.1 - 1.4e-05 24.6 2.3 1.9e-05 24.1 1.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EIM79870.1 - 0.33 9.9 7.7 0.43 9.5 5.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HisKA_3 PF07730.8 EIM79870.1 - 0.35 11.2 10.4 0.46 10.8 3.8 2.3 1 1 1 2 2 2 0 Histidine kinase DUF3365 PF11845.3 EIM79870.1 - 0.48 10.2 3.3 0.92 9.3 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) FA PF08736.6 EIM79870.1 - 3.7 7.4 9.2 6.9 6.5 0.4 3.1 1 1 2 3 3 3 0 FERM adjacent (FA) Metal_resist PF13801.1 EIM79870.1 - 6.5 6.7 19.6 8.9 6.3 3.5 2.7 1 1 1 2 2 2 0 Heavy-metal resistance HEAT PF02985.17 EIM79871.1 - 9.4e-08 31.5 0.2 2.5e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EIM79871.1 - 0.00034 20.9 0.1 0.51 10.7 0.0 2.3 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EIM79871.1 - 0.004 17.4 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EIM79871.1 - 0.012 16.1 0.4 0.11 12.9 0.1 2.4 1 1 2 3 3 3 0 HEAT-like repeat RIX1 PF08167.7 EIM79871.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis COesterase PF00135.23 EIM79872.1 - 2e-11 43.3 0.0 2.5e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.13 EIM79873.1 - 2.3e-13 49.6 1.1 4e-13 48.8 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM79873.1 - 7.6e-07 28.9 7.2 1.7e-06 27.8 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 EIM79875.1 - 6.1e-78 261.5 4.8 1.3e-77 260.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EIM79876.1 - 2e-23 82.6 46.2 3.3e-23 81.9 32.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3981 PF13139.1 EIM79876.1 - 0.068 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) DUF1475 PF07343.6 EIM79877.1 - 0.048 13.0 0.1 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) Pyr_redox_3 PF13738.1 EIM79879.1 - 1.7e-24 87.0 0.0 6.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM79879.1 - 2.3e-16 60.3 0.0 7.6e-09 35.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM79879.1 - 5.6e-16 57.8 0.0 8.4e-15 53.9 0.0 2.4 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM79879.1 - 7.2e-14 51.4 0.0 7e-11 41.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIM79879.1 - 4.7e-13 49.3 0.6 0.0001 22.6 0.1 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM79879.1 - 1.5e-10 40.6 0.5 8.8e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM79879.1 - 2.6e-08 33.7 0.2 7.4e-05 22.7 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EIM79879.1 - 2.9e-07 29.8 0.0 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EIM79879.1 - 3.6e-06 26.1 0.9 0.084 11.7 0.0 3.2 4 0 0 4 4 3 2 Glucose inhibited division protein A ThiF PF00899.16 EIM79879.1 - 2.8e-05 23.9 0.2 0.11 12.2 0.0 3.0 3 0 0 3 3 3 2 ThiF family Thi4 PF01946.12 EIM79879.1 - 6.6e-05 22.1 0.2 0.028 13.5 0.1 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EIM79879.1 - 8.5e-05 22.2 0.6 0.0015 18.1 0.0 2.6 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EIM79879.1 - 0.00022 20.2 0.9 0.42 9.4 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM79879.1 - 0.00045 19.1 0.1 0.079 11.7 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EIM79879.1 - 0.0012 17.9 0.1 0.31 9.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EIM79879.1 - 0.0014 18.6 0.1 0.14 12.2 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EIM79879.1 - 0.0015 17.0 0.0 0.073 11.5 0.0 2.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 EIM79879.1 - 0.0025 18.0 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EIM79879.1 - 0.0051 16.4 0.2 0.0086 15.6 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EIM79879.1 - 0.0052 16.1 0.4 0.013 14.8 0.1 1.8 2 0 0 2 2 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EIM79879.1 - 0.0056 16.4 0.4 0.055 13.1 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CPSase_L_chain PF00289.17 EIM79879.1 - 0.017 15.2 0.0 0.6 10.2 0.0 2.5 3 0 0 3 3 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 EIM79879.1 - 0.018 15.0 0.1 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Oxidored_nitro PF00148.14 EIM79879.1 - 0.021 13.4 0.0 0.34 9.4 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase LigB PF02900.13 EIM79879.1 - 0.045 12.7 0.0 0.099 11.6 0.0 1.5 1 1 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase AlaDh_PNT_C PF01262.16 EIM79879.1 - 0.05 13.1 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 EIM79879.1 - 0.053 13.8 0.0 6.5 7.0 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.1 EIM79879.1 - 0.066 12.9 0.9 3.6 7.3 0.0 3.1 3 1 1 4 4 3 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIM79879.1 - 0.071 12.4 0.1 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EIM79879.1 - 0.077 12.9 0.3 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EIM79879.1 - 0.15 12.5 0.1 11 6.5 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EIM79879.1 - 0.17 11.3 0.4 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Papilloma_E5 PF03025.9 EIM79880.1 - 0.32 10.9 10.3 1.1 9.2 1.2 2.8 1 1 1 2 2 2 0 Papillomavirus E5 MFS_1 PF07690.11 EIM79881.1 - 1.5e-21 76.5 26.6 1.5e-21 76.5 18.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79881.1 - 9.6e-13 47.5 27.0 3.2e-12 45.7 18.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 EIM79882.1 - 2.1e-54 184.9 0.0 2.7e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM79882.1 - 0.021 14.9 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EB PF01683.13 EIM79883.1 - 0.18 11.9 26.0 0.48 10.5 2.6 4.9 4 1 1 5 5 5 0 EB module Defensin_beta_2 PF13841.1 EIM79883.1 - 0.57 10.5 8.1 0.15 12.4 0.9 3.2 2 0 0 2 2 2 0 Beta defensin stn_TNFRSF12A PF12191.3 EIM79883.1 - 4.6 7.2 7.3 0.23 11.5 0.9 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Form_Nir_trans PF01226.12 EIM79884.1 - 2.9e-65 219.6 16.6 3.5e-65 219.3 11.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Tannase PF07519.6 EIM79885.1 - 4.2e-83 279.6 0.0 5.3e-82 276.0 0.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EIM79885.1 - 0.048 13.5 0.0 0.083 12.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_C14 PF00656.17 EIM79886.1 - 1.2e-13 51.2 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Caspase domain MCM PF00493.18 EIM79888.1 - 3e-137 456.8 0.0 4.3e-137 456.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EIM79888.1 - 2e-30 105.8 30.6 2e-30 105.8 21.2 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EIM79888.1 - 2.9e-16 60.0 0.1 7.9e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIM79888.1 - 1.1e-07 31.3 0.0 3.1e-06 26.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIM79888.1 - 6.8e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIM79888.1 - 0.0011 18.6 0.1 0.015 14.8 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIM79888.1 - 0.0014 18.1 0.1 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 EIM79888.1 - 0.03 14.3 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ank_4 PF13637.1 EIM79889.1 - 0.013 16.0 0.2 0.056 13.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM79889.1 - 0.035 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Methyltransf_3 PF01596.12 EIM79889.1 - 0.096 11.7 0.0 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase adh_short PF00106.20 EIM79890.1 - 5.9e-21 75.0 3.2 3.6e-20 72.5 2.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79890.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79890.1 - 4e-09 36.3 0.3 7.6e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 KR domain MtrB PF05440.7 EIM79890.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B adh_short PF00106.20 EIM79891.1 - 3e-21 76.0 4.5 2e-20 73.3 3.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79891.1 - 7.1e-13 48.8 0.1 1.4e-12 47.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79891.1 - 7.2e-09 35.5 1.2 1.6e-08 34.4 0.2 1.8 2 0 0 2 2 2 1 KR domain YjeF_N PF03853.10 EIM79891.1 - 0.009 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus MtrB PF05440.7 EIM79891.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B adh_short PF00106.20 EIM79892.1 - 6e-20 71.8 4.3 5.2e-19 68.7 3.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79892.1 - 9.6e-14 51.7 0.1 1.8e-13 50.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79892.1 - 5.3e-08 32.7 0.3 1e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 KR domain Ferrochelatase PF00762.14 EIM79892.1 - 0.005 15.8 0.0 0.0068 15.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase YjeF_N PF03853.10 EIM79892.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RRM_2 PF04059.7 EIM79893.1 - 2.7e-32 110.5 0.3 3.4e-32 110.3 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EIM79893.1 - 4.5e-05 23.3 0.1 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM79893.1 - 9.5e-05 21.9 0.1 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YliH PF10799.3 EIM79895.1 - 0.089 12.4 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) adh_short PF00106.20 EIM79896.1 - 2.9e-25 89.1 0.3 4.1e-25 88.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79896.1 - 1.3e-13 51.2 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79896.1 - 5.5e-12 45.7 0.1 8e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Ferrochelatase PF00762.14 EIM79896.1 - 0.0025 16.8 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase YjeF_N PF03853.10 EIM79896.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.20 EIM79897.1 - 3.7e-21 75.7 5.5 4.3e-20 72.2 3.8 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79897.1 - 2.8e-12 46.9 0.1 4.9e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79897.1 - 3.1e-09 36.7 1.5 1.2e-08 34.8 1.0 1.8 1 1 0 1 1 1 1 KR domain Ferrochelatase PF00762.14 EIM79897.1 - 0.0025 16.8 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MtrB PF05440.7 EIM79897.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.7 1 1 1 2 2 2 1 Tetrahydromethanopterin S-methyltransferase subunit B RAB3GAP2_C PF14656.1 EIM79897.1 - 0.094 10.8 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus NmrA PF05368.8 EIM79897.1 - 0.13 11.4 0.2 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family SNase PF00565.12 EIM79898.1 - 9.2e-61 202.8 1.5 6.8e-21 74.5 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EIM79898.1 - 3.2e-20 72.1 0.0 6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Tudor domain UPF0240 PF06784.6 EIM79901.1 - 0.0082 15.8 2.8 0.018 14.6 1.9 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) TBPIP PF07106.8 EIM79901.1 - 1.3 8.5 10.5 2.3 7.7 7.2 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mod_r PF07200.8 EIM79901.1 - 2.5 8.0 16.2 7.2 6.5 11.2 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EIM79901.1 - 4.7 6.7 15.8 6.1 6.3 9.7 2.0 2 0 0 2 2 2 0 IncA protein Macoilin PF09726.4 EIM79901.1 - 5.5 5.1 13.4 16 3.6 9.3 1.6 1 1 0 1 1 1 0 Transmembrane protein MIF4G PF02854.14 EIM79903.1 - 4.6e-50 169.9 0.0 1.5e-27 96.3 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EIM79903.1 - 5.4e-29 101.1 6.5 5.4e-29 101.1 4.5 3.1 3 0 0 3 3 3 1 Up-frameshift suppressor 2 adh_short PF00106.20 EIM79904.1 - 1.4e-21 77.1 0.6 7.6e-21 74.7 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM79904.1 - 8.1e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM79904.1 - 3.9e-07 29.9 0.0 2.2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 KR domain Ferrochelatase PF00762.14 EIM79904.1 - 0.0053 15.7 0.0 0.0071 15.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase F-box-like PF12937.2 EIM79905.1 - 2.8e-07 30.1 2.5 1e-06 28.3 1.7 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM79905.1 - 0.12 12.0 3.7 9.4 6.0 0.0 3.5 3 0 0 3 3 3 0 F-box domain Zn_clus PF00172.13 EIM79906.1 - 0.00011 22.0 32.5 0.0021 17.8 8.3 3.3 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S6 PF01250.12 EIM79907.1 - 2.3e-09 36.9 0.0 2.7e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 DUF1678 PF07913.6 EIM79907.1 - 0.015 14.8 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) HAD_2 PF13419.1 EIM79908.1 - 3.6e-07 30.5 0.0 5.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM79908.1 - 1.1e-06 29.2 0.0 3.1e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3128 PF11326.3 EIM79909.1 - 1.1e-18 67.1 0.5 1.7e-18 66.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) FR47 PF08445.5 EIM79910.1 - 1.7e-07 30.8 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EIM79910.1 - 2.7e-07 30.5 0.1 7.7e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM79910.1 - 8.4e-06 25.6 0.1 0.00047 20.0 0.0 2.9 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM79910.1 - 2.7e-05 24.2 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM79910.1 - 0.00036 20.6 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EIM79910.1 - 0.00091 18.8 0.2 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM79910.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CTP_transf_3 PF02348.14 EIM79910.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase MOZ_SAS PF01853.13 EIM79910.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family MFS_1 PF07690.11 EIM79911.1 - 3.3e-46 157.6 33.1 3.3e-44 151.0 11.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79911.1 - 4e-10 38.8 9.6 4e-10 38.8 6.6 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM79911.1 - 1.6e-09 36.6 7.5 2.8e-05 22.7 5.3 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EIM79911.1 - 2e-06 26.3 3.2 3.5e-06 25.5 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIM79911.1 - 0.00087 17.5 4.9 0.00087 17.5 3.4 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.3 EIM79911.1 - 0.0019 16.7 15.5 0.0029 16.1 2.2 2.7 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EIM79911.1 - 0.0077 15.9 0.3 0.029 14.1 0.2 2.0 1 0 0 1 1 1 1 MFS_1 like family DASH_Dad2 PF08654.5 EIM79912.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Med14 PF08638.6 EIM79913.1 - 2.4e-51 173.7 0.0 4.2e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 MFS_1 PF07690.11 EIM79914.1 - 3.4e-47 160.8 34.9 2.6e-42 144.8 17.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79914.1 - 7.5e-13 47.8 13.4 7.5e-13 47.8 9.3 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EIM79914.1 - 2.9e-05 22.4 6.7 4.3e-05 21.9 4.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EIM79914.1 - 6e-05 21.6 6.9 6e-05 21.6 4.8 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIM79914.1 - 0.013 15.2 6.3 0.033 13.9 0.1 3.2 2 1 1 3 3 3 0 MFS_1 like family ATG22 PF11700.3 EIM79914.1 - 0.019 13.4 16.3 0.033 12.6 8.5 2.4 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like OATP PF03137.15 EIM79914.1 - 0.025 12.6 2.1 0.057 11.4 1.4 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HEAT PF02985.17 EIM79915.1 - 7.9e-13 47.3 0.2 0.049 13.7 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIM79915.1 - 6.1e-08 32.8 0.1 0.00092 19.4 0.0 4.3 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EIM79915.1 - 0.00027 21.3 0.4 1.2 9.6 0.1 4.5 2 1 2 4 4 4 1 HEAT-like repeat Pkinase PF00069.20 EIM79915.1 - 0.0019 17.4 0.0 0.016 14.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Adaptin_N PF01602.15 EIM79915.1 - 0.0048 15.2 0.0 2.6 6.2 0.0 2.7 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 EIM79915.1 - 0.023 14.5 0.0 6.3 6.6 0.0 3.2 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIM79915.1 - 0.075 13.4 0.0 6.4 7.2 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EIM79915.1 - 0.34 10.9 1.4 1.5 8.8 0.0 2.8 2 1 1 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Chromo PF00385.19 EIM79916.1 - 7.4e-10 38.3 1.4 1.4e-09 37.4 1.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4295 PF14128.1 EIM79916.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) SOG2 PF10428.4 EIM79916.1 - 6 5.3 10.2 8.9 4.8 7.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Med12 PF09497.5 EIM79917.1 - 1.3e-23 82.7 0.7 1.3e-22 79.5 0.0 2.8 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 UCH PF00443.24 EIM79918.1 - 3.7e-11 42.6 0.0 4.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 EIM79918.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_L13e PF01294.13 EIM79918.1 - 0.029 13.8 0.6 0.06 12.8 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L13e CD34_antigen PF06365.7 EIM79918.1 - 0.17 11.4 0.1 0.62 9.6 0.0 1.9 3 0 0 3 3 3 0 CD34/Podocalyxin family RRM_6 PF14259.1 EIM79919.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM79919.1 - 0.00079 19.0 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CD99L2 PF12301.3 EIM79921.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF667 PF05018.8 EIM79923.1 - 0.11 11.7 0.1 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Ank PF00023.25 EIM79926.1 - 1.9e-19 68.3 2.3 4.7e-09 35.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIM79926.1 - 4e-17 62.3 0.3 2.9e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIM79926.1 - 8.5e-14 50.3 0.7 1.1e-05 25.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIM79926.1 - 1.3e-12 47.5 0.6 7.7e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM79926.1 - 2e-11 44.0 0.1 0.00028 21.2 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SelP_N PF04592.9 EIM79926.1 - 0.016 14.6 8.3 0.018 14.4 5.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EIM79926.1 - 0.021 13.8 4.7 0.022 13.7 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter G-alpha PF00503.15 EIM79929.1 - 1.1e-120 402.9 0.0 1.3e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM79929.1 - 3.5e-10 39.4 0.0 4.4e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIM79929.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIM79929.1 - 0.023 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.8 EIM79929.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 EIM79929.1 - 0.08 12.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.11 EIM79930.1 - 1.1e-44 152.6 42.5 1.1e-44 152.6 29.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79930.1 - 1.1e-13 50.5 29.6 3.5e-13 48.9 20.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIM79930.1 - 8.8e-06 24.1 4.7 8.8e-06 24.1 3.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-DHHC PF01529.15 EIM79930.1 - 0.053 12.9 0.9 25 4.2 0.0 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase F-box-like PF12937.2 EIM79931.1 - 4.5e-08 32.6 0.5 1.8e-07 30.7 0.3 2.1 1 1 0 1 1 1 1 F-box-like Toxin_29 PF08116.6 EIM79932.1 - 0.33 10.7 2.0 0.5 10.1 1.4 1.3 1 0 0 1 1 1 0 PhTx neurotoxin family Transp_cyt_pur PF02133.10 EIM79933.1 - 2.6e-26 92.2 31.5 3.1e-26 91.9 21.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_44 PF12891.2 EIM79935.1 - 1.6e-40 139.1 2.0 2.5e-40 138.4 1.4 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 44 CBM_11 PF03425.8 EIM79935.1 - 0.021 14.5 0.1 0.076 12.6 0.1 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) F-box-like PF12937.2 EIM79936.1 - 3.1e-08 33.2 0.9 1.1e-07 31.4 0.6 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM79937.1 - 3.9e-06 26.4 2.9 9.7e-06 25.2 1.4 2.3 2 1 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM79937.1 - 0.079 12.7 0.3 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Leucine rich repeat Fungal_trans PF04082.13 EIM79938.1 - 4.2e-13 48.7 0.0 9.1e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM79938.1 - 1.6e-07 31.0 8.0 3.9e-07 29.8 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EIM79938.1 - 5.5e-07 29.5 11.8 0.0026 18.0 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM79938.1 - 1.5e-06 28.2 8.0 1.9e-05 24.7 1.7 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM79938.1 - 8.3e-06 25.7 17.1 9.7e-05 22.4 2.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EIM79938.1 - 4.8 7.5 7.1 12 6.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Vhr1 PF04001.8 EIM79939.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Vhr1 EURL PF06937.6 EIM79940.1 - 0.15 11.4 2.3 0.21 10.9 1.6 1.1 1 0 0 1 1 1 0 EURL protein AF-4 PF05110.8 EIM79941.1 - 5.7 4.6 14.6 9.3 3.9 10.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.9 EIM79941.1 - 8.1 4.3 8.8 12 3.7 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein S1-P1_nuclease PF02265.11 EIM79942.1 - 8.5e-73 245.0 0.0 1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease AA_permease_2 PF13520.1 EIM79943.1 - 1.1e-68 231.8 49.8 1.3e-68 231.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM79943.1 - 1.6e-20 72.9 43.4 2.4e-20 72.3 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.26 EIM79944.1 - 0.01 15.8 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain DUF883 PF05957.8 EIM79946.1 - 0.00051 20.3 25.8 0.0011 19.2 2.5 3.8 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) DUF4366 PF14283.1 EIM79946.1 - 0.0011 18.4 1.0 0.0018 17.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Apolipoprotein PF01442.13 EIM79946.1 - 0.0083 15.6 16.4 0.65 9.4 11.3 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3810 PF12725.2 EIM79946.1 - 0.014 14.3 0.2 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2681 PF10883.3 EIM79946.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF2413 PF10310.4 EIM79946.1 - 0.37 9.5 19.6 0.53 9.0 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2959 PF11172.3 EIM79946.1 - 0.54 9.9 12.9 1.1 8.9 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) YtxH PF12732.2 EIM79946.1 - 1.8 8.9 26.4 0.21 11.9 3.0 4.1 2 2 1 3 3 3 0 YtxH-like protein ApoLp-III PF07464.6 EIM79946.1 - 4 7.4 22.0 0.64 10.0 2.8 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Peptidase_C14 PF00656.17 EIM79947.1 - 5.5e-17 62.2 0.0 9.6e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM79947.1 - 0.00062 18.9 0.0 0.0023 17.0 0.0 1.9 2 1 0 2 2 2 1 CHAT domain Raptor_N PF14538.1 EIM79947.1 - 0.059 13.2 0.1 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain FrhB_FdhB_N PF04422.8 EIM79947.1 - 0.076 12.8 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Peptidase_C14 PF00656.17 EIM79948.1 - 2.1e-13 50.5 0.0 3.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIM79949.1 - 1.6e-18 67.2 0.0 3.9e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM79949.1 - 0.0014 17.8 0.0 0.0037 16.4 0.0 1.7 2 0 0 2 2 2 1 CHAT domain AAA_18 PF13238.1 EIM79950.1 - 4.9e-07 30.1 0.0 1.7e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM79950.1 - 5e-05 24.0 0.0 7.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM79950.1 - 0.034 14.0 0.0 0.072 12.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain CPT PF07931.7 EIM79950.1 - 0.048 13.2 0.0 0.088 12.4 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 EIM79950.1 - 0.092 12.7 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM79950.1 - 0.11 11.5 0.3 0.16 11.0 0.2 1.4 1 1 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EIM79950.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EIM79950.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein APH PF01636.18 EIM79951.1 - 3.2e-09 36.8 0.0 5e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EIM79951.1 - 0.00015 20.5 0.0 0.05 12.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Ank PF00023.25 EIM79952.1 - 0.0072 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EIM79952.1 - 0.025 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM79952.1 - 0.08 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM79952.1 - 0.091 13.0 0.0 0.5 10.7 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat FAD_binding_2 PF00890.19 EIM79954.1 - 4.2e-89 299.2 1.1 6.8e-89 298.5 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EIM79954.1 - 3.2e-23 81.3 0.0 8.2e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EIM79954.1 - 3.1e-14 52.6 0.2 8.7e-10 38.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM79954.1 - 6.9e-11 42.3 1.0 2.5e-07 30.7 0.6 3.5 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM79954.1 - 4.7e-10 39.3 0.6 2.9e-09 36.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIM79954.1 - 1.2e-09 37.7 2.1 3e-09 36.4 1.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM79954.1 - 3.7e-07 29.5 0.3 6.3e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIM79954.1 - 5.1e-07 28.8 3.3 0.0001 21.2 0.7 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIM79954.1 - 4.1e-06 25.5 7.2 6.9e-05 21.4 0.5 3.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EIM79954.1 - 9.5e-06 24.8 3.7 0.0079 15.3 0.7 2.7 2 1 1 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.1 EIM79954.1 - 9.5e-06 25.8 3.2 1.2e-05 25.4 0.6 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM79954.1 - 0.00044 20.0 0.6 0.011 15.5 0.4 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIM79954.1 - 0.0031 17.8 2.2 0.052 13.9 0.2 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM79954.1 - 0.0056 15.7 1.2 0.0092 15.0 0.2 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIM79954.1 - 0.0081 15.1 0.3 0.033 13.1 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EIM79954.1 - 0.021 15.0 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EIM79954.1 - 0.07 12.6 0.4 0.18 11.3 0.3 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIM79954.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 EIM79954.1 - 0.25 10.4 3.2 0.41 9.7 0.0 2.5 3 0 0 3 3 3 0 GMC oxidoreductase GET2 PF08690.5 EIM79954.1 - 0.42 9.8 2.0 0.65 9.1 1.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Methyltransf_2 PF00891.13 EIM79956.1 - 1.5e-18 66.8 0.0 2.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EIM79956.1 - 0.0044 16.3 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIM79956.1 - 0.0079 16.7 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM79956.1 - 0.011 15.7 0.2 0.05 13.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIM79956.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Acyl-CoA_ox_N PF14749.1 EIM79956.1 - 0.14 12.4 0.1 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GATA PF00320.22 EIM79957.1 - 2.7e-24 84.2 22.8 3.9e-16 58.0 2.2 2.4 2 0 0 2 2 2 2 GATA zinc finger eIF-5_eIF-2B PF01873.12 EIM79957.1 - 0.0094 15.6 5.7 0.18 11.4 0.1 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 zf-RING_3 PF14369.1 EIM79957.1 - 0.011 15.6 0.4 0.011 15.6 0.3 2.8 2 1 0 2 2 2 0 zinc-finger TF_Zn_Ribbon PF08271.7 EIM79957.1 - 0.033 13.5 1.6 0.033 13.5 1.1 2.8 3 1 0 3 3 3 0 TFIIB zinc-binding RRN7 PF11781.3 EIM79957.1 - 0.047 13.1 8.9 0.088 12.3 0.5 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EIM79957.1 - 0.97 9.4 9.2 0.99 9.4 0.3 2.8 2 1 1 3 3 3 0 Zinc ribbon domain Elf1 PF05129.8 EIM79957.1 - 2.2 8.0 8.7 1.5 8.5 0.1 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like CHAT PF12770.2 EIM79959.1 - 2.6e-32 112.0 0.0 4.2e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_7 PF13176.1 EIM79959.1 - 0.026 14.3 0.1 1.3 9.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM79959.1 - 4 7.4 18.3 0.082 12.8 0.2 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat Peptidase_M19 PF01244.16 EIM79960.1 - 8.5e-98 327.2 0.0 9.9e-98 326.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) YjgP_YjgQ PF03739.9 EIM79962.1 - 0.62 8.7 2.7 0.68 8.6 1.9 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Methyltransf_2 PF00891.13 EIM79963.1 - 2.1e-24 86.0 0.0 4.7e-24 84.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EIM79963.1 - 0.00038 19.8 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIM79963.1 - 0.0019 18.7 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIM79963.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 EIM79963.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EIM79963.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIM79963.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HUN PF08729.5 EIM79964.1 - 0.34 10.8 4.0 0.56 10.1 2.8 1.3 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Peptidase_M19 PF01244.16 EIM79965.1 - 9.3e-93 310.6 0.0 1.1e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ECH PF00378.15 EIM79967.1 - 5.3e-77 258.2 0.3 6.5e-77 257.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Gon7 PF08738.5 EIM79968.1 - 0.046 13.7 0.8 0.14 12.1 0.5 1.8 1 0 0 1 1 1 0 Gon7 family NTP_transferase PF00483.18 EIM79972.1 - 1.4e-40 139.1 0.0 3.2e-40 138.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIM79972.1 - 1.4e-07 31.7 0.2 3.7e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EIM79972.1 - 7.3e-05 22.4 0.5 0.00029 20.4 0.1 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase IspD PF01128.14 EIM79972.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DivIC PF04977.10 EIM79972.1 - 0.39 10.2 1.6 0.93 9.0 0.5 1.9 2 0 0 2 2 2 0 Septum formation initiator Kunitz_BPTI PF00014.18 EIM79973.1 - 0.027 14.6 0.9 0.048 13.8 0.6 1.4 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain LTP_2 PF14368.1 EIM79973.1 - 0.46 10.6 3.5 0.17 12.0 0.7 1.5 1 1 0 1 1 1 0 Probable lipid transfer Reo_sigmaC PF04582.7 EIM79975.1 - 0.0004 19.6 9.5 0.0097 15.1 0.1 3.1 3 0 0 3 3 3 2 Reovirus sigma C capsid protein Cluap1 PF10234.4 EIM79975.1 - 0.0011 18.2 7.6 0.0011 18.2 5.2 3.9 1 1 3 4 4 4 1 Clusterin-associated protein-1 DUF1664 PF07889.7 EIM79975.1 - 1.3 8.8 22.4 0.16 11.8 0.9 4.8 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) MyTH4 PF00784.12 EIM79976.1 - 2.7e-29 101.4 0.0 6.8e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.22 EIM79976.1 - 5.2e-28 97.5 0.0 8.7e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.21 EIM79976.1 - 3.6e-11 42.7 7.3 9.6e-07 28.5 3.6 2.5 2 0 0 2 2 2 2 WW domain HpcH_HpaI PF03328.9 EIM79977.1 - 3.1e-34 117.8 0.0 3.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EIM79977.1 - 0.036 12.7 0.1 0.048 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Response_reg PF00072.19 EIM79977.1 - 0.048 13.6 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Response regulator receiver domain DUF664 PF04978.7 EIM79979.1 - 0.032 14.4 1.2 0.083 13.1 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF664) KNOX2 PF03791.8 EIM79979.1 - 0.15 11.3 0.5 0.47 9.7 0.1 1.9 2 0 0 2 2 2 0 KNOX2 domain DDE_1 PF03184.14 EIM79980.1 - 0.0052 15.9 0.1 0.007 15.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM79980.1 - 0.03 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease GMC_oxred_C PF05199.8 EIM79982.1 - 1.1e-35 123.0 0.0 2e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIM79982.1 - 1.3e-33 116.4 0.0 2e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM79982.1 - 0.00016 21.6 0.1 0.00039 20.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM79982.1 - 0.0002 20.3 0.2 0.00035 19.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM79982.1 - 0.0009 18.1 0.5 0.0032 16.3 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EIM79982.1 - 0.0021 17.0 0.2 0.0035 16.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM79982.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM79982.1 - 0.011 14.1 0.2 0.045 12.2 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EIM79982.1 - 0.081 12.0 1.0 0.16 11.0 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EIM79982.1 - 0.14 12.2 0.7 3.2 7.7 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM79982.1 - 0.18 10.3 0.1 0.3 9.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 EIM79984.1 - 4.8e-41 140.8 0.0 6.1e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribonucleas_3_3 PF14622.1 EIM79986.1 - 2.7e-08 33.8 0.0 3.6e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 EIM79986.1 - 1.6e-07 31.7 0.1 2.8e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EIM79986.1 - 0.00055 20.3 0.0 0.0018 18.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain MYCBPAP PF14646.1 EIM79987.1 - 0.073 11.7 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family FUSC PF04632.7 EIM79988.1 - 0.001 17.6 6.4 0.001 17.6 4.4 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family RmuC PF02646.11 EIM79988.1 - 0.011 14.5 9.6 0.014 14.3 6.7 1.1 1 0 0 1 1 1 0 RmuC family DUF1690 PF07956.6 EIM79988.1 - 0.015 15.2 1.3 0.018 14.9 0.9 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) HemX PF04375.9 EIM79988.1 - 0.018 13.6 12.6 0.022 13.3 8.7 1.1 1 0 0 1 1 1 0 HemX GLE1 PF07817.8 EIM79988.1 - 0.028 13.3 5.6 0.036 13.0 3.9 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF2450 PF10475.4 EIM79988.1 - 0.037 12.9 2.2 0.046 12.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) ADIP PF11559.3 EIM79988.1 - 0.04 13.8 9.1 0.064 13.1 6.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 EIM79988.1 - 0.044 13.2 4.8 0.052 13.0 3.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF342 PF03961.8 EIM79988.1 - 0.044 12.1 1.0 0.051 11.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 EIM79988.1 - 0.063 12.4 2.3 0.074 12.2 1.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AIP3 PF03915.8 EIM79988.1 - 0.078 11.8 3.3 0.09 11.6 2.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Noelin-1 PF12308.3 EIM79988.1 - 0.1 12.3 4.0 0.16 11.8 2.8 1.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein HAUS-augmin3 PF14932.1 EIM79988.1 - 0.13 11.4 9.8 0.17 11.0 6.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 EIM79988.1 - 0.18 9.6 1.1 0.2 9.4 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EIM79988.1 - 0.21 10.4 9.0 0.26 10.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med10 PF09748.4 EIM79988.1 - 0.27 11.0 3.9 0.39 10.5 2.7 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Bac_GDH PF05088.7 EIM79988.1 - 0.29 8.4 3.4 0.33 8.3 2.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase YlbD_coat PF14071.1 EIM79988.1 - 0.33 11.0 5.4 0.48 10.4 3.8 1.3 1 0 0 1 1 1 0 Putative coat protein DUF1993 PF09351.5 EIM79988.1 - 0.55 10.1 7.6 0.75 9.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Histone_HNS PF00816.16 EIM79988.1 - 0.58 10.7 4.9 0.9 10.0 3.4 1.3 1 0 0 1 1 1 0 H-NS histone family Flu_NP PF00506.13 EIM79988.1 - 0.59 8.5 3.4 0.7 8.3 2.3 1.0 1 0 0 1 1 1 0 Influenza virus nucleoprotein DUF3573 PF12097.3 EIM79988.1 - 1 7.8 5.4 1.2 7.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HisKA_3 PF07730.8 EIM79988.1 - 2 8.7 6.7 4.4 7.7 4.6 1.8 1 1 0 1 1 1 0 Histidine kinase EIF4E-T PF10477.4 EIM79988.1 - 7.7 5.1 6.6 9.1 4.9 4.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NPV_P10 PF05531.7 EIM79988.1 - 9.9 6.4 13.0 0.8 9.9 2.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CCT_2 PF09425.5 EIM79989.1 - 0.26 10.8 1.3 0.45 10.0 0.9 1.4 1 0 0 1 1 1 0 Divergent CCT motif Phe_hydrox_dim PF07976.7 EIM79992.1 - 2.5e-05 23.9 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain TPR_12 PF13424.1 EIM79993.1 - 2.7e-44 148.9 16.4 1.5e-07 31.2 0.0 9.0 7 2 1 9 9 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 EIM79993.1 - 9.5e-43 142.9 41.8 0.00016 21.4 0.0 13.4 14 0 0 14 14 13 10 Tetratricopeptide repeat Apc5 PF12862.2 EIM79993.1 - 1.2e-15 57.0 19.8 0.69 9.7 0.1 11.0 4 3 7 11 11 11 5 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 EIM79993.1 - 1.4e-11 43.8 12.2 0.038 13.6 0.2 7.4 4 2 4 8 8 8 5 TPR repeat TPR_2 PF07719.12 EIM79993.1 - 1.6e-11 43.1 12.4 1.3 9.1 0.0 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat NACHT PF05729.7 EIM79993.1 - 6.5e-10 38.9 0.0 1.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF3856 PF12968.2 EIM79993.1 - 9.2e-06 25.5 6.8 0.11 12.3 0.2 5.7 3 1 4 8 8 7 2 Domain of Unknown Function (DUF3856) AAA_22 PF13401.1 EIM79993.1 - 2.5e-05 24.4 0.1 0.0016 18.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain TPR_8 PF13181.1 EIM79993.1 - 0.00018 21.0 0.0 47 4.0 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat AAA_10 PF12846.2 EIM79993.1 - 0.0019 17.7 1.4 1.6 8.1 0.0 3.9 2 1 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EIM79993.1 - 0.0026 17.4 0.0 0.011 15.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain TPR_17 PF13431.1 EIM79993.1 - 0.0051 16.9 3.1 20 5.7 0.0 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM79993.1 - 0.0067 17.0 24.2 1.1 10.0 0.2 7.3 5 3 2 7 7 7 2 Tetratricopeptide repeat DUF4003 PF13170.1 EIM79993.1 - 0.0078 15.5 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4003) NTPase_1 PF03266.10 EIM79993.1 - 0.0097 15.6 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA PF00004.24 EIM79993.1 - 0.017 15.3 0.0 0.054 13.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec34 PF04136.10 EIM79993.1 - 0.073 12.7 0.0 9 5.9 0.0 3.4 3 0 0 3 3 3 0 Sec34-like family Utp11 PF03998.8 EIM79993.1 - 0.28 10.9 0.2 4.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Utp11 protein Baculo_p47 PF05112.7 EIM79993.1 - 0.39 10.0 0.3 0.66 9.3 0.2 1.3 1 0 0 1 1 1 0 Baculovirus P47 protein TPPII_N PF12583.3 EIM79993.1 - 4.4 7.4 10.3 1.9e+02 2.1 0.0 6.6 8 0 0 8 8 7 0 Tripeptidyl peptidase II N terminal TrkH PF02386.11 EIM79994.1 - 2e-87 293.0 12.9 3.9e-84 282.2 2.0 2.1 2 0 0 2 2 2 2 Cation transport protein F-box-like PF12937.2 EIM79997.1 - 3e-10 39.6 0.4 3e-10 39.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM79997.1 - 0.049 13.3 0.2 1.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat F-box PF00646.28 EIM79997.1 - 0.15 11.7 4.3 8.7 6.1 1.1 3.7 4 0 0 4 4 4 0 F-box domain MFS_1 PF07690.11 EIM79998.1 - 6e-30 104.1 44.8 5.5e-28 97.6 13.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM79998.1 - 1.5e-12 46.8 14.9 2.4e-12 46.2 10.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM79998.1 - 2.6e-07 29.4 8.5 0.00036 19.0 0.6 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein SepZ PF06066.6 EIM79998.1 - 0.054 13.4 0.9 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 SepZ MFS_1 PF07690.11 EIM80000.1 - 3.2e-27 95.1 29.4 3.2e-27 95.1 20.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM80000.1 - 6.2e-09 34.9 17.8 8.9e-09 34.4 12.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIM80000.1 - 0.00076 17.7 0.3 0.0014 16.9 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pam17 PF08566.5 EIM80000.1 - 0.021 14.5 2.2 3.5 7.2 0.3 2.7 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 PIG-P PF08510.7 EIM80001.1 - 6.8 6.3 9.9 0.11 12.0 0.8 2.4 3 0 0 3 3 3 0 PIG-P Fungal_trans PF04082.13 EIM80003.1 - 6.1e-10 38.4 0.1 9.8e-10 37.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80003.1 - 3.6e-06 26.7 10.1 5.5e-06 26.1 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXB PF12828.2 EIM80003.1 - 0.0021 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 PX-associated TPT PF03151.11 EIM80004.1 - 8.7e-29 100.1 5.8 8.7e-29 100.1 4.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIM80004.1 - 1.3e-08 34.9 22.2 3e-07 30.5 4.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EIM80004.1 - 5.7e-08 32.0 13.2 1.2e-07 30.9 9.2 1.5 1 1 0 1 1 1 1 UAA transporter family ATP-synt_C PF00137.16 EIM80006.1 - 0.04 13.8 0.2 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit C APG5 PF04106.7 EIM80008.1 - 7.8e-44 149.5 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Med31 PF05669.7 EIM80011.1 - 1.6e-33 114.4 3.7 2.1e-33 114.1 2.6 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 EIM80011.1 - 0.049 13.2 3.0 0.78 9.4 0.1 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat TrkH PF02386.11 EIM80012.1 - 1.5e-25 89.5 16.9 4.4e-19 68.2 0.0 5.3 4 2 0 4 4 4 3 Cation transport protein adh_short PF00106.20 EIM80013.1 - 8e-13 48.6 0.2 1.8e-12 47.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM80013.1 - 3.1e-07 30.4 0.0 0.0033 17.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM80013.1 - 5.3e-05 22.9 0.9 0.0014 18.3 0.6 2.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM80013.1 - 0.0007 19.6 0.2 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EIM80013.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EIM80013.1 - 0.0068 15.8 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.14 EIM80013.1 - 0.017 13.8 0.0 0.28 9.8 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM80013.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3930 PF13067.1 EIM80014.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) Peptidase_C12 PF01088.16 EIM80015.1 - 7.6e-53 178.8 0.0 1.2e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Zn_clus PF00172.13 EIM80016.1 - 2.4e-06 27.3 6.1 4.5e-06 26.4 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4372 PF14294.1 EIM80018.1 - 0.049 13.4 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) zf-C2H2 PF00096.21 EIM80020.1 - 1.7e-05 24.8 8.1 0.0036 17.5 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIM80020.1 - 0.0054 16.8 3.9 1.5 9.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIM80020.1 - 0.0066 16.7 11.1 0.56 10.6 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIM80020.1 - 0.021 15.0 1.3 7 7.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIM80020.1 - 0.048 13.4 7.9 0.78 9.5 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EIM80020.1 - 0.54 10.4 6.8 0.98 9.6 4.7 1.4 1 0 0 1 1 1 0 CHY zinc finger FRG2 PF15315.1 EIM80020.1 - 8.3 6.3 10.0 13 5.6 6.9 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SnoaL PF07366.7 EIM80022.1 - 0.0012 18.4 1.8 0.026 14.0 1.2 2.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF1850 PF08905.6 EIM80023.1 - 0.087 12.6 0.1 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1850) DUF1772 PF08592.6 EIM80024.1 - 6.4e-24 84.2 9.4 4.4e-23 81.5 6.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) KdpC PF02669.10 EIM80024.1 - 0.088 12.4 0.7 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Peptidase_C14 PF00656.17 EIM80026.1 - 3.2e-19 69.6 0.1 5e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIM80030.1 - 4.4e-17 62.5 0.1 1.1e-16 61.3 0.1 1.6 1 1 0 1 1 1 1 Caspase domain Propep_M14 PF02244.11 EIM80030.1 - 0.049 13.2 0.2 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Pex19 PF04614.7 EIM80030.1 - 0.066 12.8 0.6 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Pex19 protein family DUF2706 PF10913.3 EIM80031.1 - 0.12 12.0 1.9 8 6.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) CAF-1_p150 PF11600.3 EIM80032.1 - 0.00093 18.6 15.1 0.00093 18.6 10.5 3.2 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Polysacc_lyase PF14099.1 EIM80032.1 - 0.0041 16.8 5.6 0.78 9.3 1.0 2.4 2 0 0 2 2 2 2 Polysaccharide lyase DUF1850 PF08905.6 EIM80036.1 - 0.028 14.2 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) Oxidored_FMN PF00724.15 EIM80039.1 - 4.1e-85 285.7 0.0 4.7e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dor1 PF04124.7 EIM80044.1 - 1.9e-42 144.9 0.0 1e-41 142.5 0.0 2.0 1 1 0 1 1 1 1 Dor1-like family COG2 PF06148.6 EIM80044.1 - 0.0034 17.2 0.4 0.0068 16.2 0.2 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Ribonuc_L-PSP PF01042.16 EIM80048.1 - 0.0026 17.5 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_28 PF00295.12 EIM80049.1 - 3e-54 184.1 4.8 5.4e-54 183.3 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM80049.1 - 4.5e-06 26.5 31.6 0.00045 20.0 6.7 2.7 1 1 1 2 2 2 2 Right handed beta helix region Daxx PF03344.10 EIM80050.1 - 0.79 8.1 4.2 1.2 7.5 2.9 1.3 1 0 0 1 1 1 0 Daxx Family UBN2_2 PF14227.1 EIM80053.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM80053.1 - 0.0027 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.17 EIM80053.1 - 0.036 14.1 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Phg_2220_C PF09524.5 EIM80053.1 - 0.052 13.5 0.0 0.32 11.0 0.0 2.1 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Trigger_N PF05697.8 EIM80054.1 - 0.017 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) SUV3_C PF12513.3 EIM80054.1 - 0.099 12.0 0.2 0.74 9.2 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal TFIIA PF03153.8 EIM80054.1 - 0.5 10.2 11.6 0.78 9.5 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.8 EIM80054.1 - 7.2 5.6 12.6 9.3 5.2 8.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cauli_VI PF01693.11 EIM80058.1 - 2.7e-11 43.3 0.1 3.2e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin Pol_alpha_B_N PF08418.5 EIM80058.1 - 0.89 9.0 5.4 1.4 8.3 3.8 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal alpha-hel2 PF14456.1 EIM80061.1 - 0.083 11.6 0.8 0.1 11.3 0.6 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 ORC6 PF05460.8 EIM80062.1 - 0.57 9.2 3.5 0.88 8.6 2.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-B_box PF00643.19 EIM80063.1 - 0.013 15.4 8.4 0.013 15.4 5.8 2.2 3 0 0 3 3 3 0 B-box zinc finger Baculo_PEP_N PF04512.7 EIM80066.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Transp_cyt_pur PF02133.10 EIM80070.1 - 1.5e-114 382.9 36.8 1.7e-114 382.7 25.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 EIM80071.1 - 8.1e-52 175.9 0.0 1.2e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80071.1 - 8.3e-48 162.7 0.0 1.1e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIM80071.1 - 9.7e-08 31.6 0.5 1.8e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EIM80071.1 - 0.0074 15.9 3.7 0.013 15.1 2.6 1.4 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 EIM80071.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM80071.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIM80071.1 - 0.017 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prok-RING_1 PF14446.1 EIM80071.1 - 0.031 14.0 3.9 0.064 12.9 2.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EIM80071.1 - 0.043 13.1 0.2 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 EIM80071.1 - 0.1 12.6 1.1 0.21 11.6 0.8 1.6 1 0 0 1 1 1 0 C1-like domain OrfB_Zn_ribbon PF07282.6 EIM80071.1 - 2 8.0 3.6 4.4 7.0 2.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DIOX_N PF14226.1 EIM80072.1 - 4.9e-26 91.5 0.0 7.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM80072.1 - 9.5e-16 57.9 0.0 2.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EIM80073.1 - 7.8e-19 67.5 0.0 1.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80073.1 - 2.9e-06 27.0 9.1 4.9e-06 26.3 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_3 PF07969.6 EIM80074.1 - 3.2e-66 224.2 0.0 3.9e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM80074.1 - 0.0032 17.2 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM80074.1 - 0.0041 16.8 0.1 0.33 10.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family CTP_transf_2 PF01467.21 EIM80075.1 - 1.5e-18 67.3 0.0 1.8e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase SapA PF02199.10 EIM80075.1 - 0.025 14.3 0.2 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Saposin A-type domain DUF187 PF02638.10 EIM80075.1 - 0.057 12.2 0.2 0.072 11.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 DUF500 PF04366.7 EIM80075.1 - 0.096 12.1 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF500) tRNA-synt_2 PF00152.15 EIM80076.1 - 1.5e-72 244.2 0.1 2.4e-72 243.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EIM80076.1 - 3.2e-23 82.0 0.4 5.9e-23 81.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EIM80076.1 - 4.2e-05 23.3 0.1 0.00012 21.8 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Acetyltransf_6 PF13480.1 EIM80076.1 - 0.089 12.7 0.1 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HrpA_pilin PF09589.5 EIM80076.1 - 0.11 12.8 6.6 0.38 11.1 4.0 2.2 2 0 0 2 2 2 0 HrpA pilus formation protein Transp_cyt_pur PF02133.10 EIM80077.1 - 0.69 8.4 6.8 0.093 11.2 1.7 1.8 2 1 0 2 2 2 0 Permease for cytosine/purines, uracil, thiamine, allantoin IMPDH PF00478.20 EIM80078.1 - 1.5e-135 451.6 0.5 3.4e-133 443.9 0.3 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EIM80078.1 - 2.8e-17 62.2 0.2 1.7e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EIM80078.1 - 1.2e-10 40.8 0.7 2.4e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EIM80078.1 - 1.4e-09 37.6 5.1 8.3e-08 31.7 2.4 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EIM80078.1 - 7.4e-05 22.1 1.8 0.00044 19.5 1.2 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EIM80078.1 - 0.0012 17.9 0.9 0.0027 16.8 0.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 EIM80078.1 - 0.043 12.7 1.0 0.52 9.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) IGPS PF00218.16 EIM80078.1 - 0.051 12.6 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Glyco_hydro_3 PF00933.16 EIM80079.1 - 4.8e-67 226.0 0.0 6.3e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain YlzJ PF14035.1 EIM80079.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 YlzJ-like protein VHS PF00790.14 EIM80080.1 - 1.3e-12 47.5 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIM80081.1 - 2.7e-07 30.4 0.2 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 GAT domain COG7 PF10191.4 EIM80082.1 - 3.2e-70 237.0 3.7 2e-36 125.2 0.2 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) Sec10 PF07393.6 EIM80082.1 - 0.015 13.4 0.0 0.041 12.0 0.0 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec10 TarH PF02203.10 EIM80082.1 - 0.022 14.5 0.9 0.022 14.5 0.6 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue Pyr_redox_dim PF02852.17 EIM80083.1 - 1e-41 141.3 5.1 5.1e-41 139.1 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EIM80083.1 - 4.1e-37 128.0 19.8 2.5e-35 122.2 13.7 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM80083.1 - 5e-19 68.4 12.7 1.3e-17 63.9 1.9 3.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM80083.1 - 2e-11 43.6 0.2 2e-11 43.6 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EIM80083.1 - 2.5e-10 39.7 0.9 2.5e-10 39.7 0.7 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIM80083.1 - 4.6e-10 39.9 0.8 2.6e-06 27.6 0.4 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM80083.1 - 1.6e-07 31.2 5.4 0.001 19.0 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM80083.1 - 1.1e-06 27.4 12.4 5.9e-05 21.7 0.1 4.1 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.19 EIM80083.1 - 3.1e-06 26.2 4.1 3.1e-06 26.2 2.8 4.2 3 1 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.1 EIM80083.1 - 3.2e-05 23.0 0.9 0.014 14.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIM80083.1 - 0.00034 19.6 23.0 0.14 11.0 0.3 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EIM80083.1 - 0.00039 20.0 4.9 0.047 13.2 0.1 3.3 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EIM80083.1 - 0.00041 19.5 6.4 0.00048 19.2 0.0 3.1 3 0 0 3 3 3 1 Thi4 family DUF4479 PF14794.1 EIM80083.1 - 0.0014 18.1 1.3 0.69 9.4 0.2 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4479) FAD_binding_3 PF01494.14 EIM80083.1 - 0.004 16.2 14.3 0.044 12.8 0.9 3.4 3 0 0 3 3 3 1 FAD binding domain THF_DHG_CYH_C PF02882.14 EIM80083.1 - 0.22 10.6 4.0 0.19 10.7 0.3 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 EIM80083.1 - 1.4 7.7 7.8 0.44 9.4 0.3 3.0 3 1 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EIM80083.1 - 4.1 7.0 7.6 0.14 11.8 0.6 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3435 PF11917.3 EIM80084.1 - 1e-39 136.4 0.5 1.5e-39 135.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-Di19 PF05605.7 EIM80084.1 - 0.093 12.8 10.5 5 7.3 0.2 4.9 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding AAA_12 PF13087.1 EIM80085.1 - 2.9e-56 190.0 0.0 4.7e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM80085.1 - 3.6e-51 174.0 0.0 5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM80085.1 - 2.9e-10 39.7 2.2 3.2e-10 39.6 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIM80085.1 - 3.3e-10 39.8 0.0 9.3e-06 25.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 EIM80085.1 - 3.9e-06 26.3 0.0 1.5e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EIM80085.1 - 3.8e-05 23.3 0.1 1.2 8.5 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EIM80085.1 - 0.1 12.8 0.3 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GAS PF13851.1 EIM80085.1 - 0.51 9.5 1.4 0.82 8.8 1.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-RanBP PF00641.13 EIM80086.1 - 2.5e-05 23.2 12.7 0.00082 18.4 0.4 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Apc1 PF12859.2 EIM80087.1 - 2.1e-10 40.7 0.7 7.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EIM80087.1 - 0.00032 20.7 3.9 0.42 10.9 0.0 4.3 4 0 0 4 4 4 2 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.15 EIM80088.1 - 1.3e-94 315.9 0.0 1.5e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2313 PF10076.4 EIM80088.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) PIH1 PF08190.7 EIM80089.1 - 4.8e-29 101.8 0.0 3.5e-26 92.4 0.0 2.1 1 1 1 2 2 2 2 pre-RNA processing PIH1/Nop17 GMC_oxred_N PF00732.14 EIM80090.1 - 5.6e-70 235.8 0.0 8.4e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM80090.1 - 3.9e-34 118.0 0.0 7.2e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM80090.1 - 3.5e-07 29.4 1.2 5.4e-06 25.5 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM80090.1 - 7.4e-07 28.3 0.2 0.0096 14.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EIM80090.1 - 2.3e-05 23.5 0.5 3.5e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM80090.1 - 0.004 17.1 0.1 0.0099 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM80090.1 - 0.09 11.8 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIM80090.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EIM80090.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BCS1_N PF08740.6 EIM80091.1 - 7e-29 100.7 1.4 7e-29 100.7 1.0 2.0 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EIM80091.1 - 6.8e-15 55.4 0.0 1.2e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM80091.1 - 0.00018 21.5 0.0 0.00018 21.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EIM80091.1 - 0.00045 19.2 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIM80091.1 - 0.003 18.3 0.5 0.024 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIM80091.1 - 0.0055 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 EIM80091.1 - 0.081 12.4 0.8 0.2 11.1 0.0 2.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIM80091.1 - 0.097 12.4 1.5 0.48 10.2 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain FemAB PF02388.11 EIM80091.1 - 0.19 10.3 6.6 0.38 9.3 4.6 1.4 1 0 0 1 1 1 0 FemAB family Ycf1 PF05758.7 EIM80091.1 - 0.48 8.0 4.2 13 3.2 3.4 2.0 2 0 0 2 2 2 0 Ycf1 AAA_11 PF13086.1 EIM80091.1 - 0.69 9.4 6.3 5.4 6.5 1.6 2.6 2 1 1 3 3 3 0 AAA domain RNase_H2-Ydr279 PF09468.5 EIM80091.1 - 2.8 7.0 9.6 2.5 7.2 3.8 2.1 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) AAA_23 PF13476.1 EIM80091.1 - 2.9 8.1 12.6 5.2 7.3 0.4 2.7 2 1 0 2 2 2 0 AAA domain GAGA_bind PF06217.7 EIM80091.1 - 3 7.7 9.8 0.43 10.5 2.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4501 PF14946.1 EIM80092.1 - 2.8 7.3 5.3 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) GMC_oxred_N PF00732.14 EIM80093.1 - 3.9e-66 223.2 0.0 5.1e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM80093.1 - 3.8e-36 124.5 0.1 6.6e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM80093.1 - 6.7e-06 25.2 0.1 0.016 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM80093.1 - 0.00033 19.6 0.2 0.00065 18.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein VirE_N PF08800.5 EIM80093.1 - 0.021 14.5 0.0 0.14 11.8 0.0 2.0 1 1 1 2 2 2 0 VirE N-terminal domain NAD_binding_8 PF13450.1 EIM80093.1 - 0.061 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM80093.1 - 0.13 11.0 1.4 2.4 6.8 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain DUF2953 PF11167.3 EIM80094.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) COX14 PF14880.1 EIM80095.1 - 9.9e-07 28.2 0.9 9.9e-07 28.2 0.6 1.8 2 1 0 2 2 2 1 Cytochrome oxidase c assembly MoaF PF10703.4 EIM80095.1 - 0.12 11.3 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F WD40 PF00400.27 EIM80096.1 - 6.5e-23 79.7 20.5 0.00017 21.3 0.4 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EIM80096.1 - 2.2e-14 53.2 0.0 4.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain TauD PF02668.11 EIM80098.1 - 1.7e-56 191.7 3.1 4e-56 190.5 0.2 1.9 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIM80098.1 - 2.6e-06 27.7 0.1 0.065 13.6 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF971) DUF2442 PF10387.4 EIM80098.1 - 0.0034 17.3 0.0 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2442) DUF159 PF02586.9 EIM80100.1 - 6.3e-41 140.2 0.3 4e-40 137.5 0.2 1.8 1 1 0 1 1 1 1 Uncharacterised ACR, COG2135 CUE PF02845.11 EIM80101.1 - 6.6e-08 31.8 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain DSPc PF00782.15 EIM80102.1 - 5.6e-26 90.6 0.0 1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EIM80102.1 - 0.0002 21.6 0.0 0.0017 18.6 0.0 2.5 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EIM80102.1 - 0.03 14.5 0.1 0.075 13.2 0.1 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIM80102.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIM80102.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF159 PF02586.9 EIM80103.1 - 6e-50 169.6 0.3 9.2e-49 165.7 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised ACR, COG2135 Glyco_hydro_61 PF03443.9 EIM80104.1 - 3e-61 207.0 0.1 5.1e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EIM80104.1 - 1.8e-09 37.0 9.5 1.8e-09 37.0 6.6 2.0 1 1 0 1 1 1 1 Fungal cellulose binding domain eIF-5a PF01287.15 EIM80105.1 - 2.1e-27 94.8 0.5 3.2e-27 94.2 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EIM80105.1 - 2.5e-05 23.8 0.8 5.8e-05 22.6 0.6 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EIM80105.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain HAMP PF00672.20 EIM80106.1 - 8.6e-67 221.2 34.2 4.4e-08 33.1 0.2 11.0 10 0 0 10 10 10 10 HAMP domain HATPase_c PF02518.21 EIM80106.1 - 4.3e-28 97.2 0.4 1.7e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM80106.1 - 2.4e-22 79.0 1.3 8.9e-22 77.2 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIM80106.1 - 3e-17 62.3 2.6 1.7e-16 59.9 0.7 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AcylCoA_dehyd_C PF12186.3 EIM80106.1 - 0.0095 15.7 22.6 19 5.1 0.0 9.2 10 1 1 11 11 11 0 Acyl-CoA dehydrogenase C terminal Histone PF00125.19 EIM80106.1 - 0.037 14.1 1.1 0.36 10.9 0.2 2.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Pox_A_type_inc PF04508.7 EIM80106.1 - 0.11 12.3 0.0 7.2 6.6 0.0 4.0 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat TetR_C_5 PF08360.6 EIM80106.1 - 0.18 11.7 0.5 54 3.7 0.0 4.3 6 0 0 6 6 6 0 QacR-like protein, C-terminal region FYVE PF01363.16 EIM80106.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Potyvirid-P3 PF13608.1 EIM80106.1 - 0.23 10.5 5.4 0.18 10.8 0.1 3.4 3 1 0 3 3 3 0 Protein P3 of Potyviral polyprotein CCDC-167 PF15188.1 EIM80106.1 - 0.31 11.0 4.0 65 3.5 0.0 5.8 7 0 0 7 7 7 0 Coiled-coil domain-containing protein 167 DUF2365 PF10157.4 EIM80106.1 - 2.5 7.9 27.7 7.2 6.4 0.0 9.3 8 3 1 11 11 11 0 Uncharacterized conserved protein (DUF2365) NAAA-beta PF15508.1 EIM80106.1 - 7.3 7.0 8.3 36 4.7 0.1 6.0 10 0 0 10 10 9 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Baculo_VP1054 PF05789.6 EIM80106.1 - 8.7 5.4 5.0 1.4e+02 1.4 0.0 3.7 4 0 0 4 4 4 0 Baculovirus VP1054 protein PAP_assoc PF03828.14 EIM80110.1 - 2.1e-15 56.4 0.2 5.7e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIM80110.1 - 4.5e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain AATase PF07247.7 EIM80111.1 - 0.029 12.9 0.5 0.17 10.3 0.0 1.9 2 0 0 2 2 2 0 Alcohol acetyltransferase LSM PF01423.17 EIM80113.1 - 3.3e-18 64.9 0.0 3.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT PF02985.17 EIM80114.1 - 1.8e-20 71.0 13.3 6.2e-05 22.7 0.0 10.1 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EIM80114.1 - 1.9e-18 66.3 10.3 3.1e-09 37.0 0.0 7.9 7 2 3 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 EIM80114.1 - 7e-15 55.0 5.6 9.7e-06 25.7 0.0 7.3 3 2 4 7 7 7 5 HEAT repeats IBN_N PF03810.14 EIM80114.1 - 2.2e-11 43.5 0.3 5.5e-10 39.0 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EIM80114.1 - 1.1e-06 28.2 8.4 0.0029 17.3 0.0 5.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EIM80114.1 - 0.011 14.4 0.1 0.98 8.0 0.0 2.9 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 EIM80114.1 - 0.099 12.5 0.3 8.7 6.2 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) PPR_2 PF13041.1 EIM80115.1 - 1.1e-08 34.8 0.1 1.1e-05 25.2 0.0 4.7 6 1 1 7 7 7 1 PPR repeat family PPR_3 PF13812.1 EIM80115.1 - 0.0027 17.8 1.7 0.46 10.8 0.0 4.4 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EIM80115.1 - 0.0069 16.2 1.8 1.8 8.7 0.0 4.7 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 EIM80115.1 - 0.015 14.7 2.3 4 7.0 0.0 4.1 4 0 0 4 4 4 0 PPR repeat ECSIT PF06239.6 EIM80115.1 - 0.12 11.2 0.0 13 4.5 0.0 2.6 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway F-box-like PF12937.2 EIM80116.1 - 3.7e-06 26.5 0.6 1.2e-05 24.9 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM80116.1 - 1.7 8.3 12.1 1.1 8.9 0.5 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Beta-lactamase PF00144.19 EIM80117.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase 4HBT_3 PF13622.1 EIM80118.1 - 0.11 12.1 1.0 0.12 12.0 0.7 1.0 1 0 0 1 1 1 0 Thioesterase-like superfamily Mito_fiss_reg PF05308.6 EIM80118.1 - 1.2 8.4 4.8 1.1 8.5 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Lon_C PF05362.8 EIM80122.1 - 4.2e-64 215.6 1.9 2.2e-62 210.0 1.3 2.3 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EIM80122.1 - 7e-22 78.0 0.0 1.7e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM80122.1 - 3.7e-10 39.6 0.0 7.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON PF02190.11 EIM80122.1 - 4.2e-09 36.3 0.0 7.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EIM80122.1 - 1.3e-06 27.8 0.0 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EIM80122.1 - 0.00016 21.7 3.8 0.00024 21.1 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIM80122.1 - 0.00016 20.7 0.1 0.0022 17.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIM80122.1 - 0.00038 20.4 0.1 0.0016 18.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EIM80122.1 - 0.00061 20.6 0.1 0.0023 18.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EIM80122.1 - 0.0014 18.5 0.1 0.0064 16.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIM80122.1 - 0.0031 17.6 1.3 0.1 12.7 0.1 3.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIM80122.1 - 0.0035 16.1 0.1 0.013 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EIM80122.1 - 0.0072 15.7 0.4 0.02 14.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM80122.1 - 0.016 15.4 0.1 0.045 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM80122.1 - 0.018 14.7 0.2 0.08 12.7 0.1 2.2 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EIM80122.1 - 0.064 12.6 0.1 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 EIM80122.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EIM80122.1 - 0.08 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIM80122.1 - 0.19 11.8 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EIM80122.1 - 0.32 10.5 1.5 0.45 10.0 0.3 1.8 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.20 EIM80126.1 - 4.4e-05 22.7 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80126.1 - 0.0028 16.7 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIE_beta PF02186.10 EIM80127.1 - 0.00054 19.9 0.1 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain CAP_N PF01213.14 EIM80127.1 - 0.21 10.8 3.0 0.35 10.1 2.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Flu_C_NS2 PF03555.9 EIM80128.1 - 0.14 12.0 0.3 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) zf-MYND PF01753.13 EIM80129.1 - 1.8e-10 40.5 18.3 3.8e-10 39.4 12.7 1.6 1 0 0 1 1 1 1 MYND finger DNA_pol_B_palm PF14792.1 EIM80131.1 - 1.3e-25 89.6 0.1 2.4e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EIM80131.1 - 2e-19 68.8 2.7 3.3e-19 68.1 0.4 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EIM80131.1 - 1.1e-17 63.4 0.0 3.6e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EIM80131.1 - 6.4e-09 35.8 0.0 2.3e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EIM80131.1 - 0.00084 19.4 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EIM80131.1 - 0.0053 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH PF00633.18 EIM80131.1 - 0.09 12.5 0.4 0.88 9.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif p450 PF00067.17 EIM80132.1 - 7.9e-67 225.7 0.0 9.2e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIM PF00412.17 EIM80133.1 - 4.7e-26 90.6 21.1 1.9e-13 50.2 4.1 2.2 2 0 0 2 2 2 2 LIM domain zf-ribbon_3 PF13248.1 EIM80133.1 - 0.025 13.7 24.2 0.79 9.0 0.3 4.6 4 1 0 4 4 4 0 zinc-ribbon domain DUF2082 PF09855.4 EIM80133.1 - 0.047 13.5 0.1 0.047 13.5 0.1 3.7 3 1 1 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.5 EIM80133.1 - 0.1 12.5 19.1 2.4 8.1 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain DZR PF12773.2 EIM80133.1 - 0.13 12.1 22.4 4 7.3 4.5 4.2 2 2 0 2 2 2 0 Double zinc ribbon DUF2616 PF11077.3 EIM80133.1 - 0.22 10.9 3.8 1.5 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Cytochrom_c3_2 PF14537.1 EIM80133.1 - 1.2 9.5 13.4 5.4 7.4 3.3 2.4 2 0 0 2 2 2 0 Cytochrome c3 zf-SNAP50_C PF12251.3 EIM80133.1 - 1.8 7.8 10.2 0.45 9.8 0.2 2.5 2 1 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Lar_restr_allev PF14354.1 EIM80133.1 - 2.1 8.6 17.3 0.5 10.7 2.8 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-DNA_Pol PF08996.5 EIM80133.1 - 2.5 7.3 11.3 0.11 11.8 0.9 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 EIM80133.1 - 8.3 6.3 29.4 0.29 10.9 5.2 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain Bromo_TP PF07524.8 EIM80134.1 - 2.2e-08 33.6 0.1 3.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EIM80134.1 - 0.0013 18.7 0.1 0.0025 17.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM80134.1 - 0.15 12.2 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S MARVEL PF01284.18 EIM80135.1 - 0.02 14.6 5.5 0.038 13.8 3.8 1.5 1 1 0 1 1 1 0 Membrane-associating domain Ish1 PF10281.4 EIM80136.1 - 2.6e-40 136.0 24.4 3.8e-07 30.0 2.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EIM80136.1 - 2.6e-07 30.0 0.0 0.92 9.1 0.0 5.0 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.5 EIM80136.1 - 0.014 15.1 2.5 26 4.6 0.0 5.2 6 0 0 6 6 6 0 Slx4 endonuclease SAP PF02037.22 EIM80136.1 - 0.079 12.4 0.0 8.8 5.9 0.0 3.3 3 0 0 3 3 3 0 SAP domain Vps51 PF08700.6 EIM80136.1 - 0.16 11.8 2.0 0.46 10.3 0.0 2.7 4 0 0 4 4 4 0 Vps51/Vps67 ANT PF03374.9 EIM80136.1 - 0.23 11.5 8.0 2 8.5 0.5 4.6 4 1 3 7 7 7 0 Phage antirepressor protein KilAC domain zf-H2C2 PF09337.5 EIM80137.1 - 0.0029 16.9 0.9 0.0063 15.8 0.1 1.9 1 1 1 2 2 2 1 His(2)-Cys(2) zinc finger Gp_dh_C PF02800.15 EIM80138.1 - 6e-72 240.2 0.0 8.4e-72 239.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIM80138.1 - 8.2e-60 201.1 0.3 1.7e-59 200.1 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EIM80138.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EIM80138.1 - 0.0084 16.0 0.1 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CAF-1_p150 PF11600.3 EIM80139.1 - 0.031 13.6 0.7 0.064 12.6 0.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 EIM80140.1 - 5.8e-72 241.9 0.0 8.4e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80140.1 - 2e-38 131.9 0.0 3.3e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM80140.1 - 2.1e-05 23.6 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM80140.1 - 0.019 14.3 0.2 0.019 14.3 0.2 1.6 2 0 0 2 2 2 0 RIO1 family Dehydratase_MU PF02288.10 EIM80140.1 - 0.046 13.4 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Dehydratase medium subunit APH PF01636.18 EIM80140.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIM80142.1 - 1.5e-10 40.7 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain P16-Arc PF04699.9 EIM80143.1 - 6.5e-50 169.0 0.0 7.2e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 EIM80143.1 - 0.008 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Lyase_1 PF00206.15 EIM80146.1 - 7.5e-19 68.0 0.0 1.6e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EIM80146.1 - 2.1e-12 46.8 0.0 3.5e-11 42.9 0.0 2.7 1 1 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 EIM80146.1 - 0.13 12.6 0.6 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) WD40 PF00400.27 EIM80148.1 - 1.2e-15 56.6 8.1 6.2e-08 32.2 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat SUR7 PF06687.7 EIM80149.1 - 1.3e-09 37.9 22.0 1.5e-08 34.4 14.1 2.7 1 1 1 2 2 2 1 SUR7/PalI family Cad PF03596.8 EIM80149.1 - 1.8 8.2 7.1 0.14 11.8 1.5 1.7 2 1 0 2 2 2 0 Cadmium resistance transporter Claudin_2 PF13903.1 EIM80149.1 - 4.5 6.9 16.1 1.3 8.6 5.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Mito_carr PF00153.22 EIM80150.1 - 2.2e-71 235.6 5.0 1.1e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein V4R PF02830.13 EIM80150.1 - 0.057 13.2 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 V4R domain Tim17 PF02466.14 EIM80150.1 - 0.079 13.0 3.6 11 6.0 0.0 3.8 2 2 2 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family HEM4 PF02602.10 EIM80151.1 - 5.3e-27 94.5 0.0 3.9e-25 88.4 0.0 2.9 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HSP70 PF00012.15 EIM80152.1 - 2.5e-79 266.8 1.2 2.5e-79 266.8 0.8 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIM80152.1 - 9e-06 24.5 1.6 2e-05 23.3 1.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 EIM80152.1 - 0.0078 15.8 1.0 0.021 14.4 0.7 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Membr_traf_MHD PF10540.4 EIM80153.1 - 5.7e-19 68.2 0.0 2e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EIM80153.1 - 2.9e-08 33.4 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain F-box-like PF12937.2 EIM80154.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like Cauli_VI PF01693.11 EIM80160.1 - 3.9e-06 26.7 0.1 3.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Caulimovirus viroplasmin F-box-like PF12937.2 EIM80161.1 - 6e-07 29.0 1.0 0.03 14.0 0.3 2.9 2 0 0 2 2 2 2 F-box-like DED PF01335.16 EIM80161.1 - 0.09 12.9 0.0 8.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Death effector domain zf-C3HC4_2 PF13923.1 EIM80164.1 - 2.3e-10 40.3 9.2 4.2e-10 39.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM80164.1 - 3.1e-08 33.1 9.1 5.1e-08 32.4 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM80164.1 - 5.3e-07 29.3 9.0 9.5e-07 28.5 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIM80164.1 - 5.4e-07 29.3 9.8 9.1e-07 28.6 6.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM80164.1 - 5.4e-07 29.2 6.3 1.1e-06 28.2 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EIM80164.1 - 2.1e-06 27.4 2.1 4.2e-06 26.4 1.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EIM80164.1 - 3.2e-06 26.7 4.9 5.8e-06 25.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM80164.1 - 2.5e-05 23.9 4.0 4.9e-05 22.9 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EIM80164.1 - 0.00014 21.2 3.9 0.00026 20.4 2.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY-C PF15616.1 EIM80164.1 - 0.007 16.2 0.3 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_4 PF14570.1 EIM80164.1 - 0.034 13.7 5.3 0.16 11.6 1.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EIM80164.1 - 0.15 11.9 3.0 0.3 10.9 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EIM80164.1 - 0.15 11.9 5.3 0.97 9.3 4.2 1.9 1 1 1 2 2 2 0 Double zinc ribbon DUF1272 PF06906.6 EIM80164.1 - 0.43 10.4 6.4 1.6 8.6 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 EIM80164.1 - 2.3 8.4 8.0 8 6.6 5.5 1.8 1 1 1 2 2 2 0 RING-H2 zinc finger Helitron_like_N PF14214.1 EIM80173.1 - 3.3e-07 30.1 0.0 4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.17 EIM80175.1 - 1.2e-54 185.6 0.0 1.6e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMD PF10536.4 EIM80176.1 - 0.043 12.7 0.0 0.79 8.6 0.0 2.0 2 0 0 2 2 2 0 Plant mobile domain ACPS PF01648.15 EIM80176.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Pkinase PF00069.20 EIM80177.1 - 0.0068 15.5 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane PF01061.19 EIM80178.1 - 2.3e-75 252.3 51.7 8.8e-42 142.6 12.8 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIM80178.1 - 3.5e-35 121.2 0.0 9.3e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIM80178.1 - 1.2e-31 108.4 11.4 5.4e-27 93.4 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIM80178.1 - 2.4e-15 56.3 0.0 5.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EIM80178.1 - 1.4e-08 34.4 0.0 0.0012 18.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIM80178.1 - 2.9e-06 27.4 0.0 0.026 14.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIM80178.1 - 3.3e-06 26.3 0.0 5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIM80178.1 - 4.9e-06 26.6 0.3 0.015 15.3 0.1 3.0 3 1 0 3 3 3 2 AAA ATPase domain cobW PF02492.14 EIM80178.1 - 0.00031 20.2 0.3 0.067 12.6 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIM80178.1 - 0.0004 19.8 0.7 0.051 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EIM80178.1 - 0.00079 19.3 0.0 0.99 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EIM80178.1 - 0.0009 19.7 0.0 1.6 9.2 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EIM80178.1 - 0.0016 17.9 0.1 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EIM80178.1 - 0.0016 18.1 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EIM80178.1 - 0.0017 17.8 0.0 2.2 7.6 0.1 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_28 PF13521.1 EIM80178.1 - 0.004 17.1 1.2 0.86 9.5 0.2 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EIM80178.1 - 0.0042 17.4 0.0 0.52 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EIM80178.1 - 0.0052 16.4 0.1 0.24 11.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EIM80178.1 - 0.0055 17.5 0.0 1.8 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EIM80178.1 - 0.014 15.2 0.0 5 7.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EIM80178.1 - 0.016 15.1 0.0 0.54 10.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 EIM80178.1 - 0.017 15.0 0.0 0.97 9.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EIM80178.1 - 0.025 14.0 0.1 14 5.0 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Septin PF00735.13 EIM80178.1 - 0.032 13.2 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_19 PF13245.1 EIM80178.1 - 0.037 13.7 0.7 2.3 8.0 0.3 2.5 2 0 0 2 2 2 0 Part of AAA domain Glug PF07581.7 EIM80178.1 - 0.078 13.2 0.5 0.26 11.5 0.4 2.0 1 0 0 1 1 1 0 The GLUG motif PduV-EutP PF10662.4 EIM80178.1 - 0.11 11.9 0.2 0.97 8.9 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EIM80178.1 - 0.12 12.0 0.0 18 4.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase SMC_N PF02463.14 EIM80178.1 - 0.12 11.5 0.0 2.6 7.2 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EIM80178.1 - 0.21 11.8 0.0 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EIM80178.1 - 0.28 11.5 0.1 0.54 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 EIM80178.1 - 7.4 5.4 61.6 0.34 9.8 19.4 4.1 2 2 2 4 4 4 0 ABC-2 family transporter protein DUF1804 PF08822.6 EIM80179.1 - 0.011 15.4 0.2 0.029 14.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Got1 PF04178.7 EIM80180.1 - 9.8e-29 99.8 11.5 1.3e-28 99.5 8.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3357 PF11837.3 EIM80180.1 - 4.4 7.2 0.0 4.4 7.2 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) DUF3414 PF11894.3 EIM80181.1 - 7.1e-257 855.3 0.1 8.8e-257 855.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF427 PF04248.7 EIM80182.1 - 1.9e-35 120.3 0.0 8.7e-29 99.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) F-box-like PF12937.2 EIM80184.1 - 1.1e-08 34.5 1.0 1.1e-08 34.5 0.7 2.5 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EIM80184.1 - 0.91 9.2 3.7 0.4 10.4 0.5 2.0 2 0 0 2 2 2 0 F-box-like domain MFS_1 PF07690.11 EIM80185.1 - 1.1e-15 57.2 71.3 9.8e-14 50.8 22.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.8 EIM80188.1 - 5.2e-51 171.1 9.7 5.2e-29 100.4 0.8 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase PID PF00640.18 EIM80188.1 - 0.012 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) HTH_33 PF13592.1 EIM80188.1 - 0.044 13.3 0.3 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix F-box PF00646.28 EIM80189.1 - 0.18 11.4 0.2 21 4.8 0.0 2.5 2 0 0 2 2 2 0 F-box domain Sporozoite_P67 PF05642.6 EIM80189.1 - 0.3 8.9 4.8 0.51 8.1 3.3 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gln-synt_N PF03951.14 EIM80190.1 - 0.1 12.1 0.3 0.57 9.7 0.0 2.4 3 0 0 3 3 3 0 Glutamine synthetase, beta-Grasp domain EF1_GNE PF00736.14 EIM80191.1 - 3.8e-31 106.6 2.5 3.8e-31 106.6 1.7 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIM80191.1 - 5.8e-14 51.9 2.9 5.8e-14 51.9 2.0 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIM80191.1 - 0.00032 21.1 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM80191.1 - 0.052 13.5 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.3 EIM80191.1 - 1.3 9.1 5.7 2.2 8.4 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) WD40 PF00400.27 EIM80192.1 - 3.6e-09 36.1 23.4 0.0012 18.6 0.0 6.9 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EIM80192.1 - 3.8e-05 23.4 1.5 0.0028 17.3 0.1 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EIM80192.1 - 0.071 12.8 0.6 0.58 9.9 0.4 2.4 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EIM80193.1 - 1.1e-09 37.7 7.0 0.15 11.9 0.2 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3312 PF11768.3 EIM80193.1 - 0.14 10.3 0.0 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) T6SS-SciN PF12790.2 EIM80194.1 - 0.17 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion lipoprotein Isochorismatase PF00857.15 EIM80196.1 - 1.6e-33 116.0 0.0 2.9e-33 115.2 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Peptidase_C2 PF00648.16 EIM80197.1 - 1.2e-51 175.4 3.4 2.3e-35 122.0 0.7 2.8 2 1 0 2 2 2 2 Calpain family cysteine protease zf-DHHC PF01529.15 EIM80198.1 - 4.1e-39 133.7 8.6 4.1e-39 133.7 6.0 2.5 1 1 1 2 2 2 2 DHHC palmitoyltransferase MIG-14_Wnt-bd PF06664.7 EIM80198.1 - 0.43 9.3 4.9 0.1 11.4 0.4 1.8 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF1469 PF07332.6 EIM80198.1 - 1.4 8.6 5.5 5.6 6.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Aminotran_3 PF00202.16 EIM80199.1 - 1.9e-105 352.4 0.0 2.3e-105 352.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EIM80199.1 - 0.0024 17.0 0.0 0.0058 15.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase F-box-like PF12937.2 EIM80200.1 - 2.5e-09 36.7 2.4 3.7e-09 36.1 0.7 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM80201.1 - 3.9e-07 29.6 0.1 3.9e-07 29.6 0.1 2.4 3 0 0 3 3 3 1 F-box-like PPP4R2 PF09184.6 EIM80201.1 - 2.8 7.3 19.1 4.4 6.7 13.2 1.2 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.6 EIM80201.1 - 6.6 4.4 12.2 9.9 3.8 8.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_4 PF12799.2 EIM80202.1 - 0.034 13.7 0.0 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM80202.1 - 0.054 13.2 1.0 1.4 8.7 0.1 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EIM80202.1 - 0.094 12.8 0.1 29 5.2 0.0 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 EIM80202.1 - 0.37 11.1 2.6 68 4.3 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat YfhO PF09586.5 EIM80203.1 - 0.066 11.2 0.6 0.086 10.8 0.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 2OG-FeII_Oxy_2 PF13532.1 EIM80204.1 - 9.6e-15 54.9 0.0 1e-13 51.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.23 EIM80205.1 - 4.9e-11 42.4 0.0 6.9e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain MIP-T3 PF10243.4 EIM80207.1 - 5.8 5.2 6.6 9.8 4.5 4.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 dCMP_cyt_deam_1 PF00383.17 EIM80208.1 - 5e-11 42.1 0.0 7.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Acetyltransf_1 PF00583.19 EIM80209.1 - 2e-08 34.1 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM80209.1 - 4.6e-07 29.9 0.0 7.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM80209.1 - 3.1e-06 27.3 0.1 7e-06 26.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM80209.1 - 6e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIM80209.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM80209.1 - 0.0083 16.0 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3086 PF11285.3 EIM80209.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) 60KD_IMP PF02096.15 EIM80211.1 - 3e-26 92.3 5.7 4.5e-26 91.7 3.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4231 PF14015.1 EIM80211.1 - 1.1 9.2 3.5 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF202 PF02656.10 EIM80212.1 - 0.00017 21.7 1.8 0.014 15.6 1.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Sdh_cyt PF01127.17 EIM80212.1 - 0.067 13.0 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Hist_rich_Ca-bd PF10529.4 EIM80212.1 - 0.57 10.2 4.6 1.1 9.4 3.2 1.4 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region DUF4551 PF15087.1 EIM80214.1 - 0.1 10.9 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3328 PF11807.3 EIM80217.1 - 1.2e-47 162.3 0.0 1.4e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 EIM80218.1 - 2.1e-09 36.9 1.1 5.1e-09 35.7 0.8 1.7 1 0 0 1 1 1 1 F-box-like HLH PF00010.21 EIM80219.1 - 7.6e-14 51.1 0.1 2.2e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain G-alpha PF00503.15 EIM80220.1 - 2e-124 415.2 0.0 2.6e-124 414.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM80220.1 - 1.2e-11 44.2 0.1 1.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EIM80220.1 - 0.0044 16.5 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EIM80220.1 - 0.006 16.0 0.2 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM80220.1 - 0.031 14.4 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM80220.1 - 0.11 11.5 1.1 0.22 10.5 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EIM80220.1 - 0.13 11.7 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GST_N_3 PF13417.1 EIM80221.1 - 3.9e-09 36.6 0.0 8.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM80221.1 - 3.2e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM80221.1 - 0.00034 20.7 0.0 0.00084 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Na_H_Exchanger PF00999.16 EIM80222.1 - 1.2e-63 214.8 34.4 1.6e-63 214.5 23.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family F-box-like PF12937.2 EIM80223.1 - 5.5e-05 22.7 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.18 EIM80225.1 - 0.0045 15.8 0.1 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AMP-binding PF00501.23 EIM80226.1 - 1.2e-90 303.8 0.1 1.6e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM80226.1 - 0.079 13.9 0.1 0.47 11.4 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HUN PF08729.5 EIM80227.1 - 3.1e-11 42.9 0.0 7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 EIM80227.1 - 2.5e-06 27.3 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 1 Ubinuclein conserved middle domain DUF2457 PF10446.4 EIM80227.1 - 0.0044 15.8 6.7 0.0082 14.9 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EIM80227.1 - 0.2 9.5 12.6 0.3 8.9 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EIM80227.1 - 1.3 8.3 11.4 2.4 7.4 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EIM80227.1 - 4 6.6 12.3 7.8 5.6 8.6 1.4 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EIM80227.1 - 8.5 4.7 16.0 0.33 9.3 6.8 1.7 2 0 0 2 2 2 0 Daxx Family Velvet PF11754.3 EIM80229.1 - 5.8e-16 58.7 0.0 9.8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 EIM80230.1 - 7.3e-29 100.8 1.0 8.5e-16 58.1 0.1 2.1 1 1 0 2 2 2 2 Velvet factor SelP_N PF04592.9 EIM80230.1 - 0.17 11.2 0.9 0.23 10.8 0.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EIM80230.1 - 0.34 9.8 1.1 0.36 9.7 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 EIM80230.1 - 1.8 7.8 5.2 1.9 7.8 3.6 1.1 1 0 0 1 1 1 0 Vta1 like SET PF00856.23 EIM80231.1 - 1.3e-13 51.5 0.0 1.9e-11 44.5 0.0 2.4 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.1 EIM80231.1 - 0.0021 18.0 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain SAF PF08666.7 EIM80231.1 - 0.053 13.9 0.1 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain WD40 PF00400.27 EIM80232.1 - 1.5e-30 103.9 5.0 2e-12 46.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EIM80232.1 - 2.4e-05 22.7 0.4 0.095 10.8 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIM80232.1 - 9.1e-05 21.3 0.1 0.019 13.7 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EIM80232.1 - 0.0013 18.3 0.2 5.9 6.6 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Hira PF07569.6 EIM80232.1 - 0.046 12.9 0.0 0.34 10.0 0.0 2.2 1 1 2 3 3 3 0 TUP1-like enhancer of split Nbas_N PF15492.1 EIM80232.1 - 0.052 12.6 0.1 1.5 7.8 0.0 2.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIM80232.1 - 0.058 12.8 0.1 0.21 11.0 0.1 1.7 1 1 0 1 1 1 0 PQQ-like domain Peptidase_S9_N PF02897.10 EIM80232.1 - 0.084 11.4 0.1 1.4 7.4 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA PF00004.24 EIM80234.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_61 PF03443.9 EIM80235.1 - 5.2e-41 140.8 0.1 1.3e-40 139.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL_2 PF13472.1 EIM80236.1 - 3.2e-14 53.4 0.6 5.4e-14 52.7 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM80236.1 - 5.4e-08 32.9 1.0 2.6e-07 30.7 0.7 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EIM80236.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family KAP_NTPase PF07693.9 EIM80237.1 - 3.3 6.5 5.4 2.4 7.0 0.1 2.1 2 0 0 2 2 2 0 KAP family P-loop domain F-box-like PF12937.2 EIM80238.1 - 9.6e-09 34.8 1.2 2.7e-08 33.4 0.8 1.9 1 0 0 1 1 1 1 F-box-like YcbB PF08664.5 EIM80239.1 - 0.019 14.7 1.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 YcbB domain Ish1 PF10281.4 EIM80239.1 - 0.024 14.6 1.1 16 5.6 0.0 3.6 3 1 0 3 3 3 0 Putative stress-responsive nuclear envelope protein DUF1244 PF06844.6 EIM80239.1 - 0.11 12.3 1.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) HSDR_N_2 PF13588.1 EIM80240.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methyltransf_23 PF13489.1 EIM80241.1 - 1.1e-09 38.1 0.0 2.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM80241.1 - 3e-09 37.2 0.0 5.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM80241.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM80241.1 - 1.2e-06 28.7 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM80241.1 - 7e-06 26.4 0.0 2e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM80241.1 - 8.8e-06 24.8 0.0 1.9e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM80241.1 - 0.0001 22.8 0.0 0.00061 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIM80241.1 - 0.0005 20.1 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EIM80241.1 - 0.0017 17.6 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EIM80241.1 - 0.29 10.2 0.0 0.93 8.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 EIM80241.1 - 0.32 10.2 0.0 0.5 9.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 TPR_12 PF13424.1 EIM80242.1 - 2.5e-25 88.1 2.4 0.011 15.7 0.0 10.8 4 3 6 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 EIM80242.1 - 6e-15 54.6 4.7 0.51 10.0 0.0 8.3 2 1 7 10 10 10 7 TPR repeat TPR_7 PF13176.1 EIM80242.1 - 1.7e-09 36.7 0.1 0.51 10.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM80242.1 - 5.5e-06 26.9 13.7 0.02 15.5 0.1 7.4 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80242.1 - 0.011 15.5 16.0 39 4.5 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Bacillus_PapR PF05968.6 EIM80242.1 - 0.55 10.3 3.8 23 5.1 0.1 3.7 4 0 0 4 4 4 0 Bacillus PapR protein La PF05383.12 EIM80243.1 - 1.4e-17 63.2 0.0 2.5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EIM80243.1 - 2.4e-08 33.4 0.2 5.3e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM80243.1 - 5.4e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM80243.1 - 0.041 13.7 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 EIM80244.1 - 1.7e-06 27.6 0.5 4.6e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 EIM80246.1 - 8.6e-15 54.3 0.1 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80246.1 - 0.002 17.9 8.1 0.0035 17.2 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Joubert PF15392.1 EIM80247.1 - 5.3 6.1 5.8 2.3 7.3 0.1 2.4 1 1 1 3 3 3 0 Joubert syndrome-associated F-box-like PF12937.2 EIM80249.1 - 2.7e-07 30.1 0.4 6.5e-07 28.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like AMPKBI PF04739.10 EIM80249.1 - 0.042 13.7 2.9 0.07 12.9 0.0 2.4 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Tyr-DNA_phospho PF06087.7 EIM80250.1 - 6.1e-43 147.0 0.0 9.6e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EIM80250.1 - 0.049 13.3 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Aconitase PF00330.15 EIM80251.1 - 1.3e-177 591.0 0.2 2.1e-177 590.2 0.2 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIM80251.1 - 2.3e-45 153.8 0.0 3.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3921 PF13060.1 EIM80253.1 - 0.077 12.8 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) DUF848 PF05852.6 EIM80253.1 - 0.36 10.6 7.6 4.5 7.1 0.1 3.5 3 1 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Xpo1 PF08389.7 EIM80255.1 - 0.028 14.3 0.0 0.62 9.9 0.0 2.9 2 0 0 2 2 2 0 Exportin 1-like protein SSP160 PF06933.6 EIM80255.1 - 0.035 12.1 2.9 0.056 11.4 2.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IBN_N PF03810.14 EIM80255.1 - 0.068 13.0 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain WD40 PF00400.27 EIM80256.1 - 8.6e-29 98.3 10.3 8.9e-12 44.4 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EIM80256.1 - 0.013 13.6 1.0 0.75 7.8 0.7 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ADH_zinc_N PF00107.21 EIM80257.1 - 8.1e-22 77.1 0.1 5e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM80257.1 - 1.5e-18 67.9 0.0 3.8e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM80257.1 - 1.2e-13 50.7 0.1 9.9e-13 47.8 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EIM80258.1 - 2.7e-47 161.3 0.0 1.4e-46 158.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.1 EIM80260.1 - 1.8e-18 67.1 0.0 2.3e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM80260.1 - 4.6e-12 46.1 0.0 5.2e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM80260.1 - 5.6e-11 42.3 0.1 7.7e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIM80260.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EIM80260.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM80260.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM80260.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NAD_binding_4 PF07993.7 EIM80261.1 - 1e-23 83.5 0.0 2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM80261.1 - 2.9e-12 45.7 0.0 1.3e-11 43.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EIM80261.1 - 5e-07 29.3 0.0 8.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM80261.1 - 0.043 13.8 0.0 0.35 10.8 0.0 2.3 2 1 0 2 2 2 0 NADH(P)-binding DUF240 PF03086.9 EIM80261.1 - 0.12 12.0 0.1 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 MG032/MG096/MG288 family 2 3Beta_HSD PF01073.14 EIM80261.1 - 0.22 10.1 0.0 1.2 7.8 0.0 2.1 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2975 PF11188.3 EIM80262.1 - 0.77 9.4 4.4 0.87 9.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) dCMP_cyt_deam_1 PF00383.17 EIM80265.1 - 6.8e-18 64.1 0.1 8.4e-18 63.9 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EIM80265.1 - 1.8e-14 53.7 1.1 1.8e-12 47.3 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EIM80265.1 - 0.011 15.1 1.0 0.19 11.1 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases FAD_binding_3 PF01494.14 EIM80266.1 - 2.4e-15 56.4 0.0 5.4e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM80266.1 - 2.9e-07 29.7 0.2 2e-06 26.9 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM80266.1 - 8.7e-07 28.8 0.6 2.1e-06 27.6 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM80266.1 - 4.4e-06 25.7 0.8 8.3e-06 24.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM80266.1 - 3.1e-05 23.1 0.2 5.8e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EIM80266.1 - 0.00026 20.9 0.2 0.00073 19.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM80266.1 - 0.0033 16.1 0.5 0.0058 15.2 0.1 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIM80266.1 - 0.0038 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM80266.1 - 0.0077 14.7 0.0 0.0093 14.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIM80266.1 - 0.0077 15.3 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM80266.1 - 0.062 13.7 0.3 0.22 11.9 0.2 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM80266.1 - 0.19 10.5 3.2 0.15 10.8 0.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF750 PF04721.12 EIM80267.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF750) Polyoma_coat2 PF00761.15 EIM80269.1 - 0.39 10.1 7.1 0.46 9.9 4.9 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Zip PF02535.17 EIM80269.1 - 0.4 9.6 5.6 0.43 9.5 3.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.4 EIM80269.1 - 5.4 5.1 11.8 5.8 5.0 8.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 EIM80270.1 - 9.2 3.7 6.7 11 3.5 4.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cupin_2 PF07883.6 EIM80271.1 - 6.8e-06 25.5 0.2 3.2e-05 23.3 0.3 1.9 2 0 0 2 2 2 1 Cupin domain XRCC1_N PF01834.11 EIM80272.1 - 0.01 15.3 1.9 0.056 12.9 0.9 2.0 2 0 0 2 2 2 0 XRCC1 N terminal domain zf-MYND PF01753.13 EIM80276.1 - 1.2e-07 31.5 16.3 2.2e-07 30.6 11.3 1.5 1 0 0 1 1 1 1 MYND finger Ribonuc_red_lgC PF02867.10 EIM80277.1 - 1.8e-211 703.3 0.0 6.5e-211 701.5 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIM80277.1 - 2.8e-20 71.8 0.0 6.9e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIM80277.1 - 3e-12 46.8 0.1 9.2e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Peptidase_S28 PF05577.7 EIM80278.1 - 1.4e-60 205.0 0.6 1.2e-59 202.1 0.4 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 GMC_oxred_N PF00732.14 EIM80279.1 - 1.5e-60 204.8 0.2 2e-60 204.4 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM80279.1 - 4.4e-34 117.8 0.0 8.2e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM80279.1 - 0.00034 19.6 0.8 0.0019 17.1 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM80279.1 - 0.00039 20.3 0.1 0.00087 19.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM80279.1 - 0.0043 17.1 0.3 2.8 7.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM80279.1 - 0.012 14.4 0.3 0.04 12.7 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EIM80279.1 - 0.057 12.3 0.1 0.089 11.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EIM80279.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PNGaseA PF12222.3 EIM80280.1 - 5.5e-75 252.8 4.9 7.6e-75 252.3 3.4 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A BNR PF02012.15 EIM80281.1 - 1.6e-09 36.1 43.3 0.95 9.5 0.2 12.0 11 0 0 11 11 11 6 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 EIM80281.1 - 0.00098 18.7 0.0 0.058 13.0 0.0 3.0 3 0 0 3 3 3 1 Iron dependent repressor, metal binding and dimerisation domain SHS2_Rpb7-N PF03876.12 EIM80282.1 - 1.6e-15 56.9 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EIM80282.1 - 1.1e-11 44.6 0.4 2.1e-11 43.7 0.3 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EIM80282.1 - 0.0054 16.9 0.1 0.011 15.8 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SR-25 PF10500.4 EIM80290.1 - 0.00062 19.3 3.1 0.00062 19.3 2.1 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein WD40 PF00400.27 EIM80293.1 - 1.7e-49 164.0 23.8 8.3e-12 44.5 0.3 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EIM80293.1 - 6.1e-11 41.8 0.4 6.1e-11 41.8 0.3 1.9 2 0 0 2 2 2 1 F-box-like Nucleoporin_N PF08801.6 EIM80293.1 - 7.2e-05 21.7 0.1 0.3 9.7 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EIM80293.1 - 0.00034 18.8 11.9 0.063 11.3 0.1 4.3 2 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box PF00646.28 EIM80293.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain PQQ_3 PF13570.1 EIM80293.1 - 0.014 15.6 7.1 4.9 7.5 0.2 5.1 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S4 PF00163.14 EIM80294.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain zf-C2H2_4 PF13894.1 EIM80297.1 - 1.3e-05 25.1 13.0 0.042 14.1 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM80297.1 - 0.042 14.1 9.2 0.23 11.8 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-MYND PF01753.13 EIM80298.1 - 9.6e-10 38.1 14.8 2.4e-09 36.9 10.3 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIM80299.1 - 1.3e-08 34.5 18.3 1.3e-08 34.5 12.7 2.2 2 0 0 2 2 2 1 MYND finger Abhydrolase_6 PF12697.2 EIM80300.1 - 4.6e-23 82.2 0.1 5.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM80300.1 - 1.4e-10 41.1 0.0 4.6e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM80300.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM80300.1 - 0.00031 21.0 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 EIM80300.1 - 0.047 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribosomal_L34 PF00468.12 EIM80301.1 - 0.096 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L34 CKS PF01111.14 EIM80302.1 - 0.027 14.2 0.1 0.027 14.2 0.1 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Abhydrolase_6 PF12697.2 EIM80303.1 - 1.1e-25 90.8 0.0 1.3e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM80303.1 - 1.4e-17 64.0 0.0 2.7e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM80303.1 - 2.5e-08 33.7 0.0 1.3e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIM80303.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EIM80303.1 - 0.042 13.6 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EIM80303.1 - 0.089 12.9 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EIM80306.1 - 8.9e-23 80.4 0.1 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIM80306.1 - 0.0025 17.5 0.1 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIM80306.1 - 0.0026 17.0 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) He_PIG PF05345.7 EIM80307.1 - 0.0018 18.2 0.1 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 Putative Ig domain Homeobox PF00046.24 EIM80310.1 - 8.9e-11 41.2 0.3 1.8e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM80310.1 - 0.00017 21.2 0.2 0.00052 19.6 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Miff PF05644.6 EIM80311.1 - 0.06 12.9 1.3 0.1 12.2 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff zf-MYND PF01753.13 EIM80312.1 - 2.3e-08 33.7 17.3 7.3e-08 32.1 12.0 1.9 1 0 0 1 1 1 1 MYND finger NAD_binding_4 PF07993.7 EIM80314.1 - 3.1e-30 104.8 0.0 7.5e-30 103.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EIM80314.1 - 1.6e-28 99.2 0.0 4.9e-28 97.6 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM80314.1 - 2.3e-10 40.3 0.0 5.9e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM80314.1 - 1.8e-06 28.0 0.0 3e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM80314.1 - 0.00011 21.0 0.0 0.00036 19.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EIM80314.1 - 0.0037 17.4 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EIM80314.1 - 0.039 12.8 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 EIM80314.1 - 0.12 12.2 0.1 0.67 9.8 0.1 2.1 1 1 0 1 1 1 0 short chain dehydrogenase PS_Dcarbxylase PF02666.10 EIM80315.1 - 5.2e-47 159.7 0.0 6.9e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase F-box-like PF12937.2 EIM80317.1 - 0.00028 20.5 4.6 0.0003 20.4 0.8 2.9 2 1 0 2 2 2 1 F-box-like Se-cys_synth_N PF12390.3 EIM80317.1 - 0.0052 16.8 0.1 1.3 9.1 0.0 2.8 2 0 0 2 2 2 2 Selenocysteine synthase N terminal TPR_11 PF13414.1 EIM80318.1 - 1.3e-42 143.2 16.7 6e-17 61.0 0.1 5.7 3 2 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 EIM80318.1 - 1e-34 116.6 0.0 4e-05 23.0 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80318.1 - 7.1e-30 100.5 8.2 0.00097 18.8 0.0 9.2 9 1 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.26 EIM80318.1 - 1.8e-21 75.6 0.2 3.7e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 EIM80318.1 - 4.7e-19 68.5 22.7 2.1e-06 28.2 0.5 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80318.1 - 6.5e-16 58.0 19.2 0.00023 21.0 0.2 6.0 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EIM80318.1 - 8.5e-16 57.5 14.7 2.5e-05 24.0 0.0 5.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM80318.1 - 5.8e-14 51.3 23.3 0.018 15.6 0.1 8.3 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIM80318.1 - 8.2e-13 48.4 20.5 0.00022 21.5 0.4 5.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIM80318.1 - 1.1e-11 43.9 6.4 0.0086 16.2 0.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EIM80318.1 - 1.9e-09 37.5 2.8 0.0008 19.5 0.3 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM80318.1 - 2.7e-08 33.0 0.2 0.17 11.7 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM80318.1 - 3.8e-08 32.5 6.5 0.05 13.4 0.0 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM80318.1 - 1.2e-06 28.5 4.4 0.067 13.6 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM80318.1 - 2.8e-06 27.0 6.8 0.012 15.5 0.1 5.5 5 1 1 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EIM80318.1 - 0.00015 21.5 1.8 0.29 11.0 0.0 3.9 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.9 EIM80318.1 - 0.0003 20.0 3.6 0.059 12.5 0.0 3.1 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_15 PF13429.1 EIM80318.1 - 0.00035 19.7 9.4 0.31 10.0 0.3 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.5 EIM80318.1 - 0.024 13.7 0.6 0.057 12.4 0.0 1.9 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like mRNA_triPase PF02940.10 EIM80318.1 - 0.037 13.7 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain SHNi-TPR PF10516.4 EIM80318.1 - 0.09 12.0 2.7 12 5.1 0.0 4.5 5 0 0 5 5 5 0 SHNi-TPR FadA PF09403.5 EIM80318.1 - 0.09 12.7 4.1 0.26 11.2 0.1 3.0 3 0 0 3 3 3 0 Adhesion protein FadA DUF4398 PF14346.1 EIM80318.1 - 0.13 12.3 20.5 4.3 7.4 2.9 5.1 4 2 0 5 5 5 0 Domain of unknown function (DUF4398) TPR_4 PF07721.9 EIM80318.1 - 0.29 11.6 12.9 8.2 7.1 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIM80318.1 - 0.68 9.8 16.5 1.8 8.5 0.6 4.5 3 2 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.2 EIM80320.1 - 6e-07 29.0 0.0 4e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 F-box-like SH3_9 PF14604.1 EIM80321.1 - 1.5e-31 107.7 1.5 5.6e-17 61.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIM80321.1 - 3.6e-27 93.5 2.9 3.7e-14 51.8 0.2 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIM80321.1 - 2.6e-18 65.2 0.2 6.5e-11 41.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EIM80321.1 - 2.8e-16 59.5 0.0 4.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.4 EIM80321.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme WD40 PF00400.27 EIM80322.1 - 1.9e-132 426.9 58.4 4.1e-13 48.6 0.1 13.9 14 0 0 14 14 14 13 WD domain, G-beta repeat Gmad1 PF10647.4 EIM80322.1 - 6.1e-12 45.4 10.3 2.2e-05 24.0 0.2 6.7 2 2 2 6 6 6 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EIM80322.1 - 3.6e-10 38.6 9.5 0.023 12.8 0.0 7.5 3 3 2 7 7 7 3 Nucleoporin Nup120/160 AAA_16 PF13191.1 EIM80322.1 - 2.8e-09 37.2 0.2 2.8e-09 37.2 0.1 2.6 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EIM80322.1 - 1.5e-07 31.2 0.0 4.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 EIM80322.1 - 1.7e-06 27.0 10.4 0.044 12.5 0.0 5.7 3 2 0 5 5 5 2 Nup133 N terminal like AAA_22 PF13401.1 EIM80322.1 - 5.5e-06 26.5 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIM80322.1 - 9.3e-05 22.2 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase PQQ_2 PF13360.1 EIM80322.1 - 0.00028 20.4 5.8 0.09 12.2 0.3 3.7 2 2 1 3 3 3 1 PQQ-like domain PD40 PF07676.7 EIM80322.1 - 0.002 17.7 12.8 42 3.9 0.0 9.3 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIM80322.1 - 0.0032 17.7 5.8 14 6.1 0.0 5.2 4 1 1 5 5 5 0 PQQ-like domain KAP_NTPase PF07693.9 EIM80322.1 - 0.0038 16.2 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 2 KAP family P-loop domain AAA PF00004.24 EIM80322.1 - 0.0047 17.1 0.0 0.019 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM80322.1 - 0.0083 15.8 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIM80322.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIM80322.1 - 0.026 15.3 0.0 0.11 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIM80322.1 - 0.036 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EIM80322.1 - 0.14 12.4 0.0 0.52 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.1 EIM80323.1 - 1.6 8.5 7.0 0.45 10.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Aldo_ket_red PF00248.16 EIM80326.1 - 6e-63 212.3 0.0 6.8e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 EIM80327.1 - 1.6e-52 178.7 0.0 4.9e-52 177.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM80327.1 - 6.5e-09 36.1 0.0 1.2e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM80327.1 - 1.4e-06 27.4 0.4 0.0021 17.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM80327.1 - 9.7e-05 22.3 1.8 0.00064 19.6 1.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIM80327.1 - 0.0001 22.2 1.1 0.00024 21.0 0.2 2.0 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 EIM80327.1 - 0.0002 21.7 0.1 0.00041 20.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EIM80327.1 - 0.00057 20.2 0.3 0.034 14.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM80327.1 - 0.0013 17.4 0.6 0.13 10.8 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase ThiF PF00899.16 EIM80327.1 - 0.0016 18.2 0.1 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.7 EIM80327.1 - 0.0017 17.3 0.0 0.0056 15.6 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EIM80327.1 - 0.0025 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIM80327.1 - 0.0028 17.0 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EIM80327.1 - 0.0028 16.7 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM80327.1 - 0.0061 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM80327.1 - 0.0079 15.0 0.3 0.017 14.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM80327.1 - 0.045 12.2 0.4 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EIM80327.1 - 0.061 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DUF2338 PF10100.4 EIM80327.1 - 0.14 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) GIDA PF01134.17 EIM80327.1 - 0.18 10.6 1.1 0.35 9.6 0.8 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 EIM80327.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Peptidase_M54 PF07998.6 EIM80328.1 - 2.3e-06 27.5 0.2 4.3e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_2 PF13574.1 EIM80328.1 - 0.09 12.8 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EIM80328.1 - 0.13 12.2 0.3 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EIM80328.1 - 0.13 12.8 0.6 0.25 11.8 0.4 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RNase_H2_suC PF08615.6 EIM80329.1 - 1.7e-25 89.4 0.1 2.6e-25 88.8 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Macoilin PF09726.4 EIM80330.1 - 0.66 8.1 12.1 0.82 7.8 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EIM80330.1 - 1.3 8.8 4.5 1.6 8.5 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_viral_N PF00242.12 EIM80330.1 - 4.9 6.0 9.8 6.3 5.7 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Period_C PF12114.3 EIM80330.1 - 6.1 6.4 16.7 10 5.6 11.6 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SWI-SNF_Ssr4 PF08549.5 EIM80330.1 - 7.1 4.8 10.5 11 4.1 7.3 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-MYND PF01753.13 EIM80331.1 - 3.3e-10 39.6 16.7 6.3e-10 38.7 11.6 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM80331.1 - 0.00043 20.0 5.0 0.0013 18.5 3.5 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 EIM80331.1 - 4.5 7.0 9.6 12 5.6 6.7 1.7 1 0 0 1 1 1 0 HIT zinc finger UBX PF00789.15 EIM80332.1 - 8.6e-11 41.7 0.4 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 UBX domain DUF572 PF04502.8 EIM80332.1 - 0.00025 20.4 18.7 0.00033 19.9 13.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) UBA PF00627.26 EIM80332.1 - 0.00057 19.6 0.0 0.029 14.2 0.0 3.1 3 0 0 3 3 3 1 UBA/TS-N domain zf-C2H2 PF00096.21 EIM80332.1 - 0.14 12.5 0.3 0.28 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIM80332.1 - 0.31 11.1 4.1 0.18 11.8 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Suc_Fer-like PF06999.7 EIM80332.1 - 1.5 8.7 5.2 0.73 9.8 1.9 1.7 1 1 1 2 2 2 0 Sucrase/ferredoxin-like CompInhib_SCIN PF11546.3 EIM80332.1 - 3.2 7.6 9.1 0.43 10.4 2.2 2.1 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN Borrelia_P83 PF05262.6 EIM80332.1 - 9.4 4.3 20.7 14 3.7 14.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Rtf2 PF04641.7 EIM80332.1 - 9.4 5.3 26.8 30 3.6 18.5 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger FAD_binding_3 PF01494.14 EIM80333.1 - 9.7e-41 139.9 0.5 5.5e-25 88.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EIM80333.1 - 1.2e-06 28.7 0.2 4.4e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM80333.1 - 3.4e-05 22.9 0.9 0.0007 18.5 0.1 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.16 EIM80333.1 - 0.0042 16.8 0.5 0.015 15.1 0.2 1.8 1 1 1 2 2 2 1 ThiF family Pyr_redox PF00070.22 EIM80333.1 - 0.019 15.3 0.2 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIM80333.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIM80333.1 - 0.057 13.5 0.2 0.13 12.3 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIM80333.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EIM80333.1 - 0.085 12.8 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.18 EIM80333.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIM80333.1 - 0.11 10.9 0.2 3.6 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.5 EIM80333.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DUF3328 PF11807.3 EIM80335.1 - 2e-15 57.0 0.3 2.4e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EIM80336.1 - 8.9e-21 74.5 0.2 1.1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_7 PF13508.1 EIM80337.1 - 9.5e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM80337.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM80337.1 - 0.00041 20.3 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM80337.1 - 0.0094 16.0 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM80337.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EIM80337.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EIM80337.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family zf-HC5HC2H_2 PF13832.1 EIM80339.1 - 4.1e-32 110.4 13.7 5.3e-32 110.0 6.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIM80339.1 - 4.6e-24 84.3 5.8 4.6e-24 84.3 4.0 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EIM80339.1 - 7.9e-21 74.9 5.8 7.9e-21 74.9 4.0 3.4 3 0 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.20 EIM80339.1 - 7.1e-19 67.5 0.3 1.6e-18 66.3 0.2 1.7 2 0 0 2 2 2 1 Bromodomain PHD_2 PF13831.1 EIM80339.1 - 4.7e-15 54.5 2.7 4.7e-15 54.5 1.9 2.8 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.12 EIM80339.1 - 1.5e-14 53.9 0.2 4.2e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 EIM80339.1 - 1.5e-09 37.3 5.4 1.5e-09 37.3 3.8 2.9 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EIM80339.1 - 0.012 14.9 0.6 0.012 14.9 0.4 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EIM80339.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4470 PF14737.1 EIM80340.1 - 4.4e-22 77.6 0.0 8.6e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM80340.1 - 1.1e-08 34.8 11.1 2.2e-08 33.8 7.7 1.5 1 0 0 1 1 1 1 MYND finger Thioredoxin PF00085.15 EIM80342.1 - 9.2e-21 73.4 0.0 5e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EIM80342.1 - 7.7e-06 26.0 0.0 3.3e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM80342.1 - 0.0057 16.7 0.0 0.26 11.4 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIM80342.1 - 0.0096 15.4 0.1 0.055 13.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 EIM80342.1 - 0.017 15.1 0.0 0.059 13.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like YbbR PF07949.7 EIM80342.1 - 0.12 12.5 0.6 0.24 11.5 0.4 1.5 1 0 0 1 1 1 0 YbbR-like protein Hist_deacetyl PF00850.14 EIM80343.1 - 1.7e-91 306.7 0.0 6.5e-91 304.8 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EIM80343.1 - 5.6e-24 84.5 0.2 1.2e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 Arb2 domain F-box-like PF12937.2 EIM80344.1 - 1.5e-06 27.7 0.2 3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like STT3 PF02516.9 EIM80345.1 - 9.9e-136 453.5 31.2 1e-133 446.8 21.6 2.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EIM80345.1 - 0.002 18.0 12.4 0.002 18.0 8.6 3.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Band_7 PF01145.20 EIM80346.1 - 1.2e-24 87.2 0.0 2.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIM80346.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family DDE_Tnp_4 PF13359.1 EIM80348.1 - 6.2e-23 81.1 0.0 8.1e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1353 PF07087.6 EIM80348.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) ABC_membrane PF00664.18 EIM80350.1 - 5.2e-47 160.5 32.7 2.9e-24 85.9 8.5 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 EIM80350.1 - 3.4e-45 153.7 0.0 5.6e-28 97.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIM80350.1 - 2.1e-11 43.4 5.5 0.0017 17.6 0.5 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM80350.1 - 1e-09 38.1 0.3 0.0013 18.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EIM80350.1 - 1.5e-08 34.9 0.1 0.12 12.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EIM80350.1 - 1.1e-06 29.1 0.4 0.00044 20.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIM80350.1 - 2.9e-05 23.5 0.0 0.095 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM80350.1 - 4e-05 23.6 0.7 0.32 10.9 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EIM80350.1 - 0.00017 20.5 0.0 0.29 10.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EIM80350.1 - 0.0002 21.3 0.2 0.19 11.6 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase MobB PF03205.9 EIM80350.1 - 0.00038 20.1 0.3 1 9.0 0.1 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIM80350.1 - 0.00038 20.9 0.3 0.87 10.0 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 EIM80350.1 - 0.00042 19.5 0.1 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 EIM80350.1 - 0.00048 18.8 0.1 0.0033 16.1 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 EIM80350.1 - 0.00096 18.6 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EIM80350.1 - 0.0017 18.4 0.3 1.7 8.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIM80350.1 - 0.0022 18.8 2.6 1.3 9.8 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 EIM80350.1 - 0.0025 18.0 0.8 0.2 11.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIM80350.1 - 0.0036 17.0 0.1 0.09 12.4 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 EIM80350.1 - 0.0041 16.5 1.2 4.5 6.6 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.12 EIM80350.1 - 0.0043 16.8 0.3 0.067 13.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EIM80350.1 - 0.0046 16.6 0.5 3.4 7.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIM80350.1 - 0.0048 17.2 0.1 4.6 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EIM80350.1 - 0.0089 15.1 0.0 0.87 8.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EIM80350.1 - 0.0097 15.3 3.4 5.7 6.2 0.1 3.3 2 1 1 3 3 3 0 AAA-like domain ATP-synt_ab PF00006.20 EIM80350.1 - 0.06 12.8 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EIM80350.1 - 0.075 13.2 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 EIM80350.1 - 0.081 12.7 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EIM80350.1 - 0.11 12.2 0.6 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 EIM80350.1 - 0.12 11.8 2.1 2.6 7.5 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EIM80350.1 - 0.13 11.5 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 EIM80350.1 - 0.18 11.6 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF285 PF03382.9 EIM80350.1 - 0.21 11.1 3.3 0.29 10.7 0.6 2.1 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 AAA_15 PF13175.1 EIM80350.1 - 0.26 10.3 0.0 0.48 9.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EIM80350.1 - 0.44 10.3 3.0 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family DUF3272 PF11676.3 EIM80350.1 - 0.51 10.3 6.4 1.8 8.6 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) F-box-like PF12937.2 EIM80351.1 - 7.2e-05 22.4 2.6 0.00014 21.5 1.8 1.5 1 0 0 1 1 1 1 F-box-like DNA_pol_delta_4 PF04081.8 EIM80352.1 - 2.4e-24 85.9 0.4 3.7e-24 85.3 0.2 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 FAD_binding_3 PF01494.14 EIM80353.1 - 1e-75 255.0 0.0 3.6e-75 253.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM80353.1 - 4.5e-25 88.2 0.0 7.5e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EIM80353.1 - 8.4e-06 25.7 0.8 1.8e-05 24.7 0.1 1.9 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM80353.1 - 9e-06 24.3 1.2 1.3e-05 23.8 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIM80353.1 - 7.9e-05 21.6 1.9 0.00012 21.1 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM80353.1 - 8.3e-05 22.5 0.1 0.00027 20.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIM80353.1 - 0.00012 21.3 0.2 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIM80353.1 - 0.00019 20.4 0.7 0.00044 19.2 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIM80353.1 - 0.00082 18.1 1.4 0.0049 15.5 0.4 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EIM80353.1 - 0.00086 18.4 0.2 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EIM80353.1 - 0.0011 17.9 0.9 0.0019 17.1 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EIM80353.1 - 0.0017 18.6 0.1 0.004 17.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EIM80353.1 - 0.0034 16.9 0.1 0.0074 15.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIM80353.1 - 0.0044 15.9 1.1 0.0071 15.3 0.8 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EIM80353.1 - 0.0091 15.6 0.3 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EIM80353.1 - 0.011 15.7 0.3 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EIM80353.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 EIM80353.1 - 0.021 14.6 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF2199 PF09965.4 EIM80353.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) ApbA PF02558.11 EIM80353.1 - 0.03 13.7 0.1 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EIM80353.1 - 0.037 14.0 0.2 0.13 12.2 0.0 2.0 3 0 0 3 3 1 0 TrkA-N domain XdhC_C PF13478.1 EIM80353.1 - 0.084 13.1 0.1 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EIM80353.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EIM80353.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF498 PF04430.9 EIM80353.1 - 0.16 11.5 0.0 22 4.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) TPR_MLP1_2 PF07926.7 EIM80354.1 - 0.0016 18.1 3.3 0.0022 17.7 2.3 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.13 EIM80354.1 - 0.03 13.8 4.4 0.045 13.2 3.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phage_GP20 PF06810.6 EIM80354.1 - 0.03 13.7 3.2 0.05 13.0 2.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ribosomal_L37 PF08561.5 EIM80354.1 - 0.038 13.5 0.7 0.078 12.5 0.5 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 Vac_Fusion PF02346.11 EIM80354.1 - 0.16 11.4 0.7 2.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF641 PF04859.7 EIM80354.1 - 0.24 11.1 3.3 0.41 10.4 2.3 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 EIM80354.1 - 0.26 11.0 5.3 4.6 7.0 1.4 2.7 2 1 1 3 3 3 0 Prefoldin subunit SPX PF03105.14 EIM80354.1 - 0.3 10.8 2.4 0.59 9.8 1.7 1.4 1 0 0 1 1 1 0 SPX domain Pex19 PF04614.7 EIM80354.1 - 0.32 10.5 6.0 0.14 11.7 0.3 2.0 1 1 1 2 2 2 0 Pex19 protein family V_ATPase_I PF01496.14 EIM80354.1 - 1.5 6.5 4.5 2 6.1 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TipAS PF07739.8 EIM80354.1 - 2.3 8.5 7.9 19 5.6 5.5 2.2 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Amidohydro_4 PF13147.1 EIM80355.1 - 2.5e-25 90.0 2.5 3.4e-25 89.6 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM80355.1 - 9.3e-15 55.0 0.0 4.2e-06 26.6 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIM80355.1 - 3.2e-12 46.0 2.9 5.6e-12 45.3 0.5 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM80355.1 - 2.4e-08 33.6 0.1 0.0013 18.0 0.0 3.1 3 1 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EIM80355.1 - 0.012 15.7 0.3 0.03 14.4 0.2 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Motile_Sperm PF00635.21 EIM80355.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 MSP (Major sperm protein) domain CN_hydrolase PF00795.17 EIM80356.1 - 1.2e-17 63.8 0.0 2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EIM80357.1 - 2.3e-08 33.2 1.1 1.4e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80357.1 - 0.00018 21.3 9.3 0.00029 20.6 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EIM80358.1 - 5.9e-19 68.1 0.0 9.3e-14 51.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIM80358.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EIM80358.1 - 0.051 13.0 0.2 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EIM80358.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Asp_Glu_race PF01177.17 EIM80359.1 - 4.8e-25 88.7 0.0 6.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Transp_cyt_pur PF02133.10 EIM80360.1 - 5.1e-108 361.4 40.3 6e-108 361.2 27.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldolase_II PF00596.16 EIM80361.1 - 7.1e-44 149.6 0.0 9.2e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.17 EIM80362.1 - 6.3e-69 232.6 0.0 1e-68 231.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF4559 PF15112.1 EIM80362.1 - 0.13 11.3 3.0 0.2 10.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) p450 PF00067.17 EIM80363.1 - 2.2e-70 237.4 0.0 5.9e-70 236.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glycos_transf_2 PF00535.21 EIM80364.1 - 5.8e-20 71.6 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIM80364.1 - 7.5e-08 32.4 0.0 0.00057 19.7 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase like family 2 ABC_membrane PF00664.18 EIM80365.1 - 1.7e-45 155.5 26.6 1.6e-26 93.3 2.3 3.8 4 0 0 4 4 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EIM80365.1 - 8.3e-41 139.5 0.0 9.1e-25 87.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EIM80365.1 - 1.2e-06 28.0 0.0 0.05 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIM80365.1 - 2.8e-06 26.7 1.0 0.66 9.1 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM80365.1 - 5.9e-06 26.4 0.7 0.56 10.1 0.0 3.8 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EIM80365.1 - 6.5e-05 22.9 0.2 0.23 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EIM80365.1 - 9.1e-05 22.9 0.0 0.24 11.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EIM80365.1 - 0.00029 20.3 0.1 0.64 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 EIM80365.1 - 0.00049 19.9 0.2 0.082 12.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EIM80365.1 - 0.00088 18.8 0.1 0.83 9.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EIM80365.1 - 0.001 19.4 4.2 0.0071 16.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EIM80365.1 - 0.0015 17.7 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 EIM80365.1 - 0.0018 16.9 0.0 0.011 14.4 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 EIM80365.1 - 0.0024 17.7 0.4 1.1 9.2 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EIM80365.1 - 0.0028 16.6 0.0 0.88 8.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EIM80365.1 - 0.0041 16.8 1.0 0.68 9.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM80365.1 - 0.018 15.8 0.1 5.7 7.7 0.0 3.2 4 0 0 4 4 2 0 AAA domain Zeta_toxin PF06414.7 EIM80365.1 - 0.022 13.8 0.0 0.57 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EIM80365.1 - 0.036 13.7 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Pox_A32 PF04665.7 EIM80365.1 - 0.052 12.8 0.4 5.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 EIM80365.1 - 0.058 13.5 0.1 4.6 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EIM80365.1 - 0.059 13.1 1.2 5 6.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EIM80365.1 - 0.074 13.3 0.0 28 5.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 EIM80365.1 - 0.11 11.9 0.6 4 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EIM80365.1 - 0.12 12.5 0.3 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EIM80365.1 - 0.14 11.6 1.2 2.5 7.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_26 PF02156.10 EIM80365.1 - 0.15 11.5 0.1 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 AAA_5 PF07728.9 EIM80365.1 - 0.2 11.3 1.3 22 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIM80365.1 - 0.25 10.9 1.0 4.6 6.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain DUF1180 PF06679.7 EIM80365.1 - 0.31 10.9 2.6 0.42 10.4 0.6 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) AAA_15 PF13175.1 EIM80365.1 - 0.4 9.6 0.0 0.65 8.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain UCH PF00443.24 EIM80366.1 - 6.6e-70 235.2 0.0 9.5e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM80366.1 - 9.5e-27 94.1 0.1 4.8e-26 91.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EIM80366.1 - 0.00018 21.8 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 EIM80366.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.15 EIM80366.1 - 0.025 14.0 0.1 0.051 13.0 0.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cytochrome_C554 PF13435.1 EIM80366.1 - 0.14 12.1 0.2 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c554 and c-prime ABC_tran PF00005.22 EIM80367.1 - 2e-44 151.2 0.0 4.4e-28 98.2 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM80367.1 - 8.9e-41 140.1 29.4 4.7e-22 78.7 3.5 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM80367.1 - 3.8e-13 49.1 2.9 0.00012 21.3 0.3 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM80367.1 - 1.2e-08 35.2 0.3 0.14 12.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EIM80367.1 - 4e-08 32.8 0.4 0.013 14.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIM80367.1 - 6.8e-06 26.5 0.3 0.0025 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIM80367.1 - 2.8e-05 24.0 0.4 0.065 13.1 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIM80367.1 - 3.5e-05 23.8 0.3 0.38 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM80367.1 - 5e-05 22.7 0.0 0.091 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EIM80367.1 - 0.00013 20.9 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 EIM80367.1 - 0.00015 22.1 0.0 0.37 11.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EIM80367.1 - 0.00035 21.3 0.0 0.6 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIM80367.1 - 0.00056 19.6 0.3 1 9.0 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 EIM80367.1 - 0.00074 18.2 0.1 0.0052 15.4 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 EIM80367.1 - 0.00081 18.9 0.2 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EIM80367.1 - 0.00084 18.8 1.1 2.3 7.6 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein DUF258 PF03193.11 EIM80367.1 - 0.00089 18.4 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM80367.1 - 0.0012 19.0 0.5 1.6 8.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIM80367.1 - 0.0023 17.6 0.1 0.1 12.2 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EIM80367.1 - 0.0026 17.9 1.7 0.18 11.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EIM80367.1 - 0.0043 16.8 0.3 0.072 12.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EIM80367.1 - 0.0073 16.6 0.0 5.2 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIM80367.1 - 0.0074 15.7 3.9 5.7 6.2 0.0 3.2 2 1 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EIM80367.1 - 0.0083 15.2 0.0 0.86 8.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 EIM80367.1 - 0.021 14.5 1.6 3.7 7.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EIM80367.1 - 0.054 12.9 0.8 2.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EIM80367.1 - 0.11 11.8 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.17 EIM80367.1 - 0.12 12.5 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 EIM80367.1 - 0.15 11.9 0.3 11 5.8 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EIM80367.1 - 0.16 11.6 0.9 3 7.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EIM80367.1 - 0.23 11.2 2.1 9.1 6.0 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.1 EIM80367.1 - 0.49 9.3 0.0 0.97 8.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rxt3 PF08642.5 EIM80368.1 - 0.00051 20.2 0.3 0.0056 16.9 0.0 2.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Ran_BP1 PF00638.13 EIM80369.1 - 2.2e-14 53.5 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain HATPase_c PF02518.21 EIM80370.1 - 5e-21 74.4 5.9 1.9e-20 72.6 4.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM80370.1 - 1.5e-16 60.3 0.0 4.8e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIM80370.1 - 8.6e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EIM80370.1 - 0.025 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EIM80370.1 - 0.081 12.7 0.5 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain zf-HC5HC2H_2 PF13832.1 EIM80371.1 - 1.7e-18 66.6 6.7 1.7e-18 66.6 4.6 4.9 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIM80371.1 - 4e-15 55.7 6.2 4e-15 55.7 4.3 4.7 3 2 0 3 3 3 2 PHD-like zinc-binding domain BAH PF01426.13 EIM80371.1 - 4.3e-12 45.8 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EIM80371.1 - 3.1e-09 36.3 42.3 3.1e-07 29.9 8.1 6.4 7 2 0 7 7 7 3 PHD-finger ELM2 PF01448.19 EIM80371.1 - 8.3e-06 26.3 0.0 2.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.22 EIM80371.1 - 1e-05 24.7 14.7 0.00019 20.7 4.2 3.2 2 0 0 2 2 2 2 GATA zinc finger PHD_2 PF13831.1 EIM80371.1 - 7.8e-05 21.9 4.3 7.8e-05 21.9 3.0 6.2 8 0 0 8 8 8 3 PHD-finger Myb_DNA-binding PF00249.26 EIM80371.1 - 0.0066 16.4 0.2 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain AT_hook PF02178.14 EIM80371.1 - 0.018 14.6 2.4 0.07 12.8 1.7 2.1 1 0 0 1 1 1 0 AT hook motif DUF3303 PF11746.3 EIM80371.1 - 0.13 12.6 0.4 0.4 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) DHFR_1 PF00186.14 EIM80372.1 - 1e-24 86.9 0.0 3.2e-24 85.3 0.0 1.8 1 1 1 2 2 2 1 Dihydrofolate reductase ABC_tran PF00005.22 EIM80373.1 - 9.7e-46 155.4 0.0 1.1e-26 93.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM80373.1 - 2.6e-44 151.7 24.8 9.9e-26 90.7 6.1 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM80373.1 - 3.5e-13 49.2 5.1 4.2e-05 22.8 0.3 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM80373.1 - 3.6e-10 39.5 1.0 0.0019 17.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EIM80373.1 - 3.6e-07 30.4 0.6 0.11 12.4 0.1 4.3 2 2 1 3 3 3 1 AAA domain AAA_23 PF13476.1 EIM80373.1 - 3e-06 27.7 0.2 0.00077 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM80373.1 - 1.2e-05 25.4 1.3 0.17 11.8 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM80373.1 - 3.9e-05 23.0 0.5 0.22 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIM80373.1 - 0.00013 22.4 0.0 0.38 11.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EIM80373.1 - 0.00022 22.0 0.3 1.9 9.3 0.0 3.5 2 1 0 3 3 3 2 AAA domain AAA PF00004.24 EIM80373.1 - 0.00046 20.4 0.5 0.18 12.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EIM80373.1 - 0.00052 19.9 0.4 0.55 10.2 0.4 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EIM80373.1 - 0.00078 19.1 0.2 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIM80373.1 - 0.0015 18.6 1.6 0.99 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIM80373.1 - 0.0015 17.7 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIM80373.1 - 0.0016 18.1 0.1 0.041 13.5 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 EIM80373.1 - 0.0017 17.2 0.0 0.26 10.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 EIM80373.1 - 0.0025 17.5 0.5 2.5 7.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EIM80373.1 - 0.0025 17.6 0.2 0.064 13.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EIM80373.1 - 0.0028 17.1 5.6 4.6 6.5 0.1 3.3 2 1 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EIM80373.1 - 0.0048 16.4 0.2 0.93 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EIM80373.1 - 0.0065 16.7 0.0 7.7 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.12 EIM80373.1 - 0.0075 15.6 0.1 3.6 6.9 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIM80373.1 - 0.012 14.7 0.0 0.85 8.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 EIM80373.1 - 0.018 14.5 0.0 6.6 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.10 EIM80373.1 - 0.027 13.1 0.1 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 EIM80373.1 - 0.03 14.4 0.1 3.8 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 EIM80373.1 - 0.05 13.0 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EIM80373.1 - 0.052 13.4 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EIM80373.1 - 0.069 12.7 0.6 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 EIM80373.1 - 0.071 12.3 0.2 7.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 EIM80373.1 - 0.093 12.6 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EIM80373.1 - 0.14 11.7 0.5 2.3 7.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 EIM80373.1 - 0.14 11.9 0.0 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Dynamin_N PF00350.18 EIM80373.1 - 0.2 11.4 1.8 4.9 6.9 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AAA_15 PF13175.1 EIM80373.1 - 0.61 9.0 0.0 1.1 8.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain APH PF01636.18 EIM80374.1 - 0.0036 17.0 0.1 0.0067 16.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM80374.1 - 0.04 12.9 0.1 0.078 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM80374.1 - 0.099 11.9 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EIM80374.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain ADIP PF11559.3 EIM80375.1 - 2.3e-18 66.5 6.6 2.3e-18 66.5 4.6 3.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 EIM80375.1 - 0.12 12.5 0.1 0.12 12.5 0.1 5.0 5 1 1 6 6 6 0 Domain of unknown function (DUF4164) AIP3 PF03915.8 EIM80375.1 - 0.32 9.8 10.8 0.036 12.9 2.6 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 ABC_membrane PF00664.18 EIM80376.1 - 1.8e-44 152.2 16.4 3.3e-27 95.6 2.3 3.8 5 0 0 5 5 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EIM80376.1 - 9.1e-42 142.5 0.0 9e-26 90.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIM80376.1 - 1.1e-10 41.1 6.3 0.00039 19.7 0.5 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM80376.1 - 1.8e-07 31.4 0.4 0.45 10.4 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EIM80376.1 - 2.4e-07 30.3 0.1 0.022 14.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIM80376.1 - 7.1e-05 22.8 0.6 0.2 11.6 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EIM80376.1 - 7.4e-05 23.2 0.1 0.19 12.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EIM80376.1 - 0.00023 20.6 0.1 0.71 9.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 EIM80376.1 - 0.00065 19.5 0.6 0.096 12.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 EIM80376.1 - 0.00097 17.8 0.0 0.0068 15.1 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_23 PF13476.1 EIM80376.1 - 0.0011 19.3 4.3 0.0072 16.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EIM80376.1 - 0.0015 17.7 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIM80376.1 - 0.0017 17.9 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EIM80376.1 - 0.0027 16.6 0.0 0.88 8.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EIM80376.1 - 0.0031 17.2 0.7 0.65 9.6 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIM80376.1 - 0.0066 16.4 1.9 1.1 9.2 0.4 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EIM80376.1 - 0.0088 15.7 0.1 0.24 11.0 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 EIM80376.1 - 0.016 16.0 0.0 5.2 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EIM80376.1 - 0.025 14.7 0.8 2.1 8.5 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EIM80376.1 - 0.047 13.4 2.5 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Glyco_hydro_26 PF02156.10 EIM80376.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Pox_A32 PF04665.7 EIM80376.1 - 0.055 12.7 0.5 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 EIM80376.1 - 0.067 13.3 4.1 5.3 7.1 0.0 3.5 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EIM80376.1 - 0.092 11.8 2.8 0.56 9.2 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_5 PF07728.9 EIM80376.1 - 0.13 12.0 1.4 23 4.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EIM80376.1 - 0.14 11.6 1.3 2.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EIM80376.1 - 0.15 12.3 0.0 31 4.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIM80376.1 - 0.26 10.9 1.0 4.7 6.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EIM80376.1 - 0.34 9.9 0.0 0.6 9.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EIM80376.1 - 0.51 9.7 5.9 5.1 6.4 0.1 3.1 2 1 0 3 3 3 0 AAA-like domain MFS_1 PF07690.11 EIM80377.1 - 7e-43 146.6 32.8 7e-43 146.6 22.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EIM80377.1 - 0.00075 19.4 2.3 0.8 9.6 0.0 3.4 3 0 0 3 3 3 2 Poxvirus virion envelope protein A14 p450 PF00067.17 EIM80379.1 - 1.2e-53 182.2 0.0 1.7e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L5_C PF00673.16 EIM80380.1 - 4.4e-22 77.6 0.0 6.5e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIM80380.1 - 8.8e-21 73.4 0.2 2.2e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Syndecan PF01034.15 EIM80382.1 - 0.029 14.0 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.20 EIM80383.1 - 3.2e-09 36.3 0.0 1.4e-06 27.6 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80383.1 - 0.043 12.8 0.0 0.088 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Phe_tRNA-synt_N PF02912.13 EIM80383.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain MFS_1 PF07690.11 EIM80384.1 - 5.1e-33 114.2 33.0 5.9e-27 94.3 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.3 EIM80384.1 - 0.01 15.3 3.3 0.014 14.9 0.9 2.2 1 1 1 2 2 2 0 Conserved membrane protein YqhR Hydantoinase_B PF02538.9 EIM80385.1 - 5.8e-155 516.5 0.0 7.8e-155 516.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EIM80385.1 - 3.8e-90 301.9 0.2 7.9e-90 300.8 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM80385.1 - 1.5e-53 180.8 1.3 2.7e-51 173.5 0.0 3.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Alpha_GJ PF03229.8 EIM80386.1 - 0.0025 18.1 1.5 0.0025 18.1 1.0 3.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J Leader_CPA1 PF08252.6 EIM80386.1 - 0.07 12.3 0.0 0.26 10.5 0.0 2.0 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide adh_short PF00106.20 EIM80387.1 - 6.3e-09 35.9 0.0 9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM80387.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MBOAT PF03062.14 EIM80388.1 - 7.5e-35 120.5 5.1 1.2e-34 119.9 3.5 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EIM80388.1 - 2.1e-05 24.4 5.8 7e-05 22.8 4.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Clr2 PF10383.4 EIM80389.1 - 9.1e-05 22.4 0.0 0.00075 19.5 0.0 2.5 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 WD40 PF00400.27 EIM80390.1 - 5e-13 48.3 0.3 1.7 8.6 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat COesterase PF00135.23 EIM80392.1 - 2.9e-83 280.4 0.0 4e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM80392.1 - 2.6e-08 33.7 0.4 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM80392.1 - 0.0026 17.5 0.1 0.0059 16.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family MFP2b PF12150.3 EIM80392.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Cytosolic motility protein Rad9 PF04139.8 EIM80393.1 - 2.7e-50 170.8 0.0 5e-50 169.9 0.0 1.4 2 0 0 2 2 2 1 Rad9 TFIIA PF03153.8 EIM80393.1 - 0.34 10.7 8.3 0.59 9.9 5.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_LMP2 PF07415.6 EIM80393.1 - 2.1 6.8 7.4 3.2 6.2 5.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Coatomer_E PF04733.9 EIM80394.1 - 1.7e-44 152.1 0.0 1.9e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 EIM80394.1 - 0.00027 20.6 0.0 1.1 9.3 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SPOR PF05036.8 EIM80394.1 - 0.017 15.2 0.2 3 8.0 0.1 3.0 2 1 1 3 3 3 0 Sporulation related domain TPR_19 PF14559.1 EIM80394.1 - 0.019 15.3 4.7 1.9 8.8 0.2 4.0 3 2 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM80394.1 - 0.039 14.5 9.9 1.9 9.3 0.2 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM80394.1 - 0.041 13.6 0.0 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM80394.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80394.1 - 0.13 12.1 2.0 10 6.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 EIM80396.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Thymidylate_kin PF02223.12 EIM80398.1 - 2.8e-42 144.2 0.0 3.8e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EIM80398.1 - 3.1e-05 23.9 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM80398.1 - 0.0048 16.7 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIM80398.1 - 0.0066 15.6 0.0 0.02 14.1 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EIM80398.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 EIM80398.1 - 0.037 13.9 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EIM80398.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CbtB PF09489.5 EIM80399.1 - 0.074 12.9 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Glyco_hydro_47 PF01532.15 EIM80400.1 - 2.2e-133 445.2 0.0 2.5e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MBOAT_2 PF13813.1 EIM80401.1 - 9.1e-13 48.0 1.9 1.8e-12 47.1 1.3 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 EIM80401.1 - 0.0014 17.7 6.7 0.0039 16.3 4.6 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Glyco_hydro_47 PF01532.15 EIM80402.1 - 1.1e-134 449.4 0.0 1.3e-134 449.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.8 EIM80403.1 - 5.2e-28 96.8 0.0 9.3e-28 95.9 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family LmjF365940-deam PF14421.1 EIM80403.1 - 0.011 15.1 1.8 0.016 14.5 1.2 1.5 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Bd3614-deam PF14439.1 EIM80403.1 - 0.044 13.6 0.1 0.088 12.6 0.0 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Zip PF02535.17 EIM80404.1 - 2.3e-52 178.0 11.2 2.7e-52 177.7 7.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2566 PF10753.4 EIM80404.1 - 0.31 10.9 0.0 0.31 10.9 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2566) DctQ PF04290.7 EIM80404.1 - 2 8.1 12.4 0.79 9.4 0.1 2.9 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Clr2 PF10383.4 EIM80405.1 - 4e-05 23.6 0.0 0.0022 17.9 0.0 2.9 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 WD40 PF00400.27 EIM80406.1 - 5.8e-10 38.6 0.7 0.0027 17.5 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat CPSF_A PF03178.10 EIM80406.1 - 0.046 12.8 0.0 0.16 11.0 0.0 1.7 1 1 0 2 2 2 0 CPSF A subunit region DUF4563 PF15124.1 EIM80406.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4563) FGGY_N PF00370.16 EIM80407.1 - 5e-60 202.8 0.0 3.9e-58 196.6 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIM80407.1 - 8.1e-59 198.5 1.5 1.4e-58 197.8 1.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Lipoprotein_9 PF03180.9 EIM80407.1 - 0.24 10.2 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 NLPA lipoprotein AAA_10 PF12846.2 EIM80408.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain KaiC PF06745.8 EIM80408.1 - 0.0085 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 KaiC Hpr_kinase_C PF07475.7 EIM80408.1 - 0.0095 15.2 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_5 PF07728.9 EIM80408.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM80408.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM80408.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GvpD PF07088.6 EIM80408.1 - 0.036 12.3 0.0 0.085 11.1 0.0 1.6 2 0 0 2 2 2 0 GvpD gas vesicle protein FtsK_SpoIIIE PF01580.13 EIM80408.1 - 0.046 13.2 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EIM80408.1 - 0.055 13.1 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RHSP PF07999.6 EIM80408.1 - 0.057 12.0 0.1 0.074 11.6 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein Sigma54_activat PF00158.21 EIM80408.1 - 0.061 12.7 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EIM80408.1 - 0.078 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIM80408.1 - 0.1 12.1 0.1 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIM80408.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EIM80408.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF4237 PF14021.1 EIM80409.1 - 1.7e-29 101.9 0.1 2.7e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) HSP20 PF00011.16 EIM80410.1 - 1.5e-14 53.6 0.0 5.3e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Pneumo_att_G PF05539.6 EIM80410.1 - 0.099 12.0 2.9 0.14 11.5 2.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RED_N PF07808.8 EIM80411.1 - 2.7e-16 59.5 5.2 2.7e-16 59.5 3.6 1.9 2 0 0 2 2 2 1 RED-like protein N-terminal region KAR9 PF08580.5 EIM80412.1 - 5.5e-07 28.2 0.3 5.5e-07 28.2 0.2 4.3 2 2 0 3 3 3 2 Yeast cortical protein KAR9 GAS2 PF02187.12 EIM80412.1 - 8.9e-05 22.1 0.2 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain YlbD_coat PF14071.1 EIM80412.1 - 0.5 10.4 4.6 12 5.9 0.0 3.6 3 1 1 4 4 4 0 Putative coat protein Cauli_AT PF03233.8 EIM80412.1 - 1.1 8.9 6.1 4.4 7.0 0.1 3.0 3 0 0 3 3 3 0 Aphid transmission protein Pkinase PF00069.20 EIM80413.1 - 1.1e-68 231.2 0.0 2.1e-68 230.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80413.1 - 5.1e-47 160.1 0.0 8.2e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIM80413.1 - 1e-20 73.9 0.0 3.9e-20 72.0 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIM80413.1 - 4e-05 22.7 0.0 6.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1777 PF08648.7 EIM80413.1 - 0.0054 16.4 8.8 0.0054 16.4 6.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DSHCT PF08148.7 EIM80413.1 - 0.068 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 EIM80413.1 - 0.12 12.0 3.1 0.21 11.3 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family RR_TM4-6 PF06459.7 EIM80413.1 - 3 7.6 5.1 6.9 6.4 3.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Thaumatin PF00314.12 EIM80416.1 - 1.2e-20 73.9 4.4 1.4e-20 73.7 3.1 1.1 1 0 0 1 1 1 1 Thaumatin family PI3_PI4_kinase PF00454.22 EIM80417.1 - 3.4e-44 151.0 0.1 1.1e-43 149.4 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EIM80417.1 - 4.2e-29 101.2 0.8 3.2e-28 98.4 0.1 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EIM80417.1 - 5.9e-12 44.8 0.2 2e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 EIM80417.1 - 2.5 8.4 7.2 1.7 8.9 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat PTR2 PF00854.16 EIM80418.1 - 2.1e-35 122.2 13.9 3.9e-35 121.3 9.7 1.5 1 1 0 1 1 1 1 POT family Anoctamin PF04547.7 EIM80419.1 - 1.1e-101 340.7 0.2 1.5e-101 340.2 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SPW PF03779.9 EIM80421.1 - 0.23 10.8 4.3 1 8.7 1.3 3.1 3 0 0 3 3 3 0 SPW repeat AATase PF07247.7 EIM80422.1 - 0.064 11.8 0.2 0.39 9.2 0.0 1.9 2 0 0 2 2 2 0 Alcohol acetyltransferase MFS_1 PF07690.11 EIM80424.1 - 1.9e-17 63.0 27.8 1.5e-12 46.9 9.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ANTH PF07651.11 EIM80425.1 - 7.5e-51 172.4 0.1 1e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 EIM80425.1 - 4.5e-06 26.6 35.9 4.5e-06 26.6 24.9 8.3 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) ENTH PF01417.15 EIM80425.1 - 0.0049 16.7 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 ENTH domain Glyco_hydro_47 PF01532.15 EIM80426.1 - 8.5e-127 423.5 0.0 1e-126 423.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSP20 PF00011.16 EIM80427.1 - 1.5e-13 50.5 0.1 2.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family AAA PF00004.24 EIM80428.1 - 1.9e-42 144.5 0.1 5.4e-42 143.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM80428.1 - 4.5e-07 30.0 0.1 3.2e-05 23.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EIM80428.1 - 6.1e-07 29.2 0.1 8e-06 25.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIM80428.1 - 4.7e-06 25.8 0.0 9.9e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIM80428.1 - 7.6e-06 25.9 0.0 2.6e-05 24.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIM80428.1 - 1.6e-05 25.0 0.0 0.0045 17.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM80428.1 - 9.7e-05 22.0 0.7 0.00051 19.7 0.4 2.2 1 1 1 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EIM80428.1 - 0.0012 18.0 0.0 0.0029 16.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 EIM80428.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EIM80428.1 - 0.0021 17.5 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIM80428.1 - 0.0032 17.3 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIM80428.1 - 0.0033 18.2 0.3 0.0092 16.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EIM80428.1 - 0.0036 16.5 0.0 0.008 15.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EIM80428.1 - 0.0044 17.1 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 EIM80428.1 - 0.0047 16.1 0.1 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_28 PF13521.1 EIM80428.1 - 0.0049 16.8 0.2 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIM80428.1 - 0.0076 15.0 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 EIM80428.1 - 0.0083 15.6 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EIM80428.1 - 0.0089 15.9 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM80428.1 - 0.01 15.2 0.3 0.05 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain DUF4200 PF13863.1 EIM80428.1 - 0.013 15.4 1.4 0.013 15.4 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_3 PF07726.6 EIM80428.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EIM80428.1 - 0.016 15.0 0.3 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EIM80428.1 - 0.019 15.2 0.1 0.069 13.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EIM80428.1 - 0.02 14.4 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIM80428.1 - 0.02 14.4 0.3 0.33 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIM80428.1 - 0.022 13.6 0.2 0.78 8.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EIM80428.1 - 0.029 13.2 0.3 0.061 12.1 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TPR_MLP1_2 PF07926.7 EIM80428.1 - 0.034 13.8 0.9 0.034 13.8 0.6 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_30 PF13604.1 EIM80428.1 - 0.039 13.5 1.6 0.091 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EIM80428.1 - 0.04 14.2 0.4 11 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIM80428.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EIM80428.1 - 0.051 12.7 0.6 0.15 11.1 0.0 2.0 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 EIM80428.1 - 0.053 13.1 0.0 0.2 11.2 0.0 1.9 1 1 1 2 2 2 0 NACHT domain UPF0079 PF02367.12 EIM80428.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GCFC PF07842.7 EIM80429.1 - 1.3e-69 234.6 1.4 1.2e-66 224.9 0.3 2.6 2 1 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EIM80429.1 - 1.1e-13 51.1 13.6 1.1e-13 51.1 9.5 3.3 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EIM80429.1 - 1.4e-13 50.3 1.5 4.7e-13 48.6 1.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIM80429.1 - 5.5e-08 32.5 0.4 5.5e-08 32.5 0.3 2.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site Tweety PF04906.8 EIM80429.1 - 0.51 8.6 0.0 0.78 8.0 0.0 1.1 1 0 0 1 1 1 0 Tweety Pro-kuma_activ PF09286.6 EIM80430.1 - 4.5e-38 130.5 0.2 8.9e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM80430.1 - 6.5e-08 32.0 0.1 1.1e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family UPF0300 PF08594.5 EIM80432.1 - 0.034 13.0 0.6 0.1 11.5 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0300) FGGY_N PF00370.16 EIM80433.1 - 1.6e-29 102.9 0.0 1.6e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIM80433.1 - 6.7e-19 68.2 0.0 1.2e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PIF1 PF05970.9 EIM80434.1 - 4.4e-62 210.1 3.0 8.6e-52 176.2 1.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIM80434.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EIM80434.1 - 4.6e-08 31.3 0.3 1.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 EIM80434.1 - 5.6e-06 26.5 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EIM80434.1 - 1.4e-05 25.1 0.1 9.3e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EIM80434.1 - 0.00038 20.1 0.2 0.001 18.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIM80434.1 - 0.00065 19.2 3.0 0.65 9.4 0.2 3.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EIM80434.1 - 0.0023 17.1 0.3 0.0073 15.5 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EIM80434.1 - 0.0041 17.3 0.2 0.0088 16.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM80434.1 - 0.0061 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EIM80434.1 - 0.013 15.0 0.1 2.7 7.5 0.0 2.7 1 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIM80434.1 - 0.016 14.9 0.4 0.041 13.5 0.3 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EIM80434.1 - 0.022 14.4 0.2 0.096 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EIM80434.1 - 0.024 13.6 0.1 0.058 12.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EIM80434.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 EIM80434.1 - 0.047 12.5 0.1 0.092 11.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EIM80434.1 - 0.051 13.7 0.1 0.15 12.2 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EIM80434.1 - 0.08 12.8 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIM80434.1 - 0.086 12.4 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF605 PF04652.11 EIM80434.1 - 0.6 9.4 13.3 1.1 8.6 9.2 1.4 1 0 0 1 1 1 0 Vta1 like Pox_A12 PF04651.8 EIM80434.1 - 5.5 7.0 10.9 0.88 9.6 4.3 1.9 1 1 1 2 2 2 0 Poxvirus A12 protein VPS9 PF02204.13 EIM80435.1 - 3.2e-17 62.4 0.0 5.6e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DUF3684 PF12449.3 EIM80435.1 - 0.0097 13.5 0.0 0.016 12.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) CENP-B_dimeris PF09026.5 EIM80435.1 - 0.75 10.0 14.4 0.024 14.8 5.0 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EIM80435.1 - 2.7 7.1 3.5 6.6 5.8 2.4 1.6 1 0 0 1 1 1 0 NOA36 protein CAF-1_p150 PF11600.3 EIM80436.1 - 0.065 12.5 0.1 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Virul_fac_BrkB PF03631.10 EIM80439.1 - 0.0078 15.6 0.1 0.0093 15.3 0.0 1.0 1 0 0 1 1 1 1 Virulence factor BrkB SecG PF03840.9 EIM80439.1 - 1.1 9.0 5.4 7.2 6.4 3.7 2.0 1 1 0 1 1 1 0 Preprotein translocase SecG subunit Ribosomal_L37e PF01907.14 EIM80441.1 - 2.4e-20 72.0 12.0 3.7e-20 71.4 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIM80441.1 - 0.00079 19.1 2.4 0.001 18.8 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EIM80441.1 - 0.047 13.3 1.5 0.062 12.9 1.0 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DEADboxA PF12343.3 EIM80441.1 - 0.091 13.0 2.0 0.11 12.7 1.4 1.2 1 0 0 1 1 1 0 Cold shock protein DEAD box A C1_1 PF00130.17 EIM80441.1 - 0.12 12.1 4.4 0.17 11.6 3.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 EIM80441.1 - 0.15 11.3 2.6 0.28 10.4 1.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.1 EIM80441.1 - 0.2 11.4 4.8 0.28 10.9 3.3 1.2 1 0 0 1 1 1 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 EIM80441.1 - 0.25 11.3 1.7 13 5.8 0.0 2.2 1 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EIM80441.1 - 0.29 10.6 3.0 3.9 7.0 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain FeS PF04060.8 EIM80441.1 - 0.29 10.7 1.9 0.44 10.1 0.2 1.9 2 0 0 2 2 2 0 Putative Fe-S cluster Ribosomal_S14 PF00253.16 EIM80441.1 - 1 8.7 10.0 2.9 7.3 0.1 2.6 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e zf-C3HC4 PF00097.20 EIM80441.1 - 1.1 9.0 6.1 1.6 8.4 4.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM80441.1 - 1.1 9.3 5.2 1.7 8.7 3.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 EIM80441.1 - 4.1 7.1 6.1 1.5e+02 2.1 4.9 2.2 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit UQ_con PF00179.21 EIM80442.1 - 1e-22 80.1 0.0 1.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF605 PF04652.11 EIM80442.1 - 3.1 7.0 7.2 3.9 6.7 5.0 1.1 1 0 0 1 1 1 0 Vta1 like CRT10 PF08728.5 EIM80443.1 - 0.3 9.0 3.2 0.3 9.0 2.2 1.0 1 0 0 1 1 1 0 CRT10 DUF262 PF03235.9 EIM80443.1 - 3.2 7.6 5.2 1.8 8.4 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF262 Pro_isomerase PF00160.16 EIM80444.1 - 6.2e-41 140.1 0.0 8.8e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S4e PF00900.15 EIM80448.1 - 8.7e-30 102.2 0.8 1.8e-29 101.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIM80448.1 - 5.8e-21 74.0 4.0 1.1e-20 73.1 2.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EIM80448.1 - 4.8e-06 25.9 0.0 9.7e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EIM80448.1 - 8.5e-06 25.2 3.4 2.5e-05 23.7 2.4 1.9 1 0 0 1 1 1 1 KOW motif MFS_1 PF07690.11 EIM80449.1 - 2.8e-43 148.0 42.3 2.6e-33 115.2 17.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF998 PF06197.8 EIM80449.1 - 0.19 11.0 38.1 0.011 15.0 2.4 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF998) SH3_9 PF14604.1 EIM80450.1 - 1.1e-07 31.2 0.0 2.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM80450.1 - 4.8e-07 29.0 0.0 1.2e-06 27.8 0.0 1.7 1 1 1 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIM80450.1 - 0.00058 19.2 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIM80450.1 - 0.014 15.5 0.8 0.027 14.6 0.5 1.6 1 1 0 1 1 1 0 Bacterial SH3 domain Spherulin4 PF12138.3 EIM80453.1 - 1.2e-51 175.5 1.5 1.4e-51 175.3 1.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 OTCace PF00185.19 EIM80453.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NMT1 PF09084.6 EIM80454.1 - 7.2e-09 35.5 0.0 9.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EIM80454.1 - 0.0016 17.8 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Cnd2 PF05786.9 EIM80455.1 - 4.2e-144 481.8 13.5 9.8e-144 480.5 9.4 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 Shikimate_dh_N PF08501.6 EIM80457.1 - 3.4e-20 71.8 0.0 1.2e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EIM80457.1 - 1.7e-08 34.6 0.0 2.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EIM80458.1 - 6.6e-111 371.0 32.3 7.5e-111 370.8 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM80458.1 - 6.5e-23 80.9 48.5 4.8e-14 51.8 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Atx10homo_assoc PF09759.4 EIM80460.1 - 1.4e-25 88.9 0.0 1.1e-23 82.8 0.0 2.8 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain TRAUB PF08164.7 EIM80462.1 - 1.9e-29 101.5 0.3 2.5e-28 97.9 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EIM80462.1 - 3e-22 79.1 0.1 3e-22 79.1 0.1 2.6 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor RRN3 PF05327.6 EIM80462.1 - 3.6 5.6 9.9 22 3.0 5.9 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EIM80462.1 - 4.5 5.6 29.4 0.13 10.7 15.8 1.7 2 0 0 2 2 2 0 Daxx Family DUF2890 PF11081.3 EIM80462.1 - 5.3 7.0 17.2 0.84 9.6 8.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Merozoite_SPAM PF07133.6 EIM80462.1 - 5.6 6.8 28.4 0.71 9.7 15.6 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) NOA36 PF06524.7 EIM80462.1 - 6.9 5.8 14.3 16 4.6 9.9 1.6 1 0 0 1 1 1 0 NOA36 protein DHHW PF14286.1 EIM80462.1 - 8.1 5.6 7.4 12 5.0 5.2 1.2 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 EIM80462.1 - 9.5 3.7 6.4 13 3.2 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LSM PF01423.17 EIM80464.1 - 2.2e-17 62.3 0.4 3e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain Pescadillo_N PF06732.6 EIM80465.1 - 1.5e-114 382.0 0.0 1.5e-114 382.0 0.0 2.3 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EIM80465.1 - 6.4e-10 39.0 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MOZART1 PF12554.3 EIM80466.1 - 1.5e-24 85.1 0.6 2e-24 84.8 0.4 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DNA_pol3_gamma3 PF12169.3 EIM80466.1 - 0.066 12.9 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III EutB PF06751.6 EIM80466.1 - 0.14 10.5 0.1 0.14 10.4 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Sporozoite_P67 PF05642.6 EIM80467.1 - 4.1 5.1 21.3 0.25 9.1 0.0 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Dus PF01207.12 EIM80469.1 - 1.3e-68 231.1 0.0 1.8e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EIM80469.1 - 0.00018 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.12 EIM80469.1 - 0.0015 18.1 0.0 0.14 11.7 0.0 2.4 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.10 EIM80469.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 EIM80469.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein p450 PF00067.17 EIM80470.1 - 3.9e-56 190.4 0.0 5.7e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M24 PF00557.19 EIM80470.1 - 0.049 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 zf-RING_2 PF13639.1 EIM80472.1 - 5.5e-11 42.1 13.1 8.5e-11 41.5 8.7 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIM80472.1 - 2.4e-10 40.0 13.5 4.2e-10 39.3 9.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIM80472.1 - 6.7e-10 38.8 12.9 1.4e-09 37.7 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM80472.1 - 9.3e-10 38.0 12.6 1.5e-09 37.3 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM80472.1 - 1.6e-08 34.0 11.1 3e-08 33.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM80472.1 - 1e-07 31.5 8.6 1.8e-07 30.7 6.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIM80472.1 - 3e-06 26.8 11.7 7.2e-06 25.6 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Nup54 PF13874.1 EIM80472.1 - 0.031 13.9 0.2 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-RING_4 PF14570.1 EIM80472.1 - 0.21 11.2 10.7 2.9 7.5 7.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EIM80472.1 - 0.26 11.0 8.9 0.83 9.4 6.2 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 EIM80472.1 - 0.29 11.0 9.4 1 9.2 6.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 EIM80472.1 - 0.41 10.8 9.2 1.4 9.0 6.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EIM80472.1 - 0.55 9.7 9.0 0.96 9.0 6.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Aminotran_5 PF00266.14 EIM80473.1 - 1.2e-25 90.0 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIM80473.1 - 1.3e-07 30.2 0.8 2.2e-07 29.5 0.2 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.27 EIM80474.1 - 4.8e-18 64.2 8.4 7.2e-08 32.0 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EIM80474.1 - 0.01 16.0 0.1 0.83 10.0 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Microvir_lysis PF04517.7 EIM80474.1 - 0.027 14.2 1.0 0.068 12.9 0.7 1.6 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus HAND PF09110.6 EIM80474.1 - 2.2 8.6 8.0 4.7 7.6 5.6 1.5 1 0 0 1 1 1 0 HAND tRNA_int_endo PF01974.12 EIM80475.1 - 5.7e-17 61.3 0.1 1e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EIM80475.1 - 1e-05 24.9 0.0 0.00078 18.9 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Zn_clus PF00172.13 EIM80476.1 - 1.1e-06 28.4 8.0 1.1e-06 28.4 5.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 EIM80476.1 - 0.04 13.6 0.7 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Mg_trans_NIPA PF05653.9 EIM80477.1 - 2.5e-87 292.6 22.2 3.7e-87 292.0 15.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIM80477.1 - 1.3e-06 28.4 5.0 1.3e-06 28.4 3.5 3.5 2 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EIM80477.1 - 2.7e-06 27.5 3.5 2.7e-06 27.5 2.5 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter PAPS_reduct PF01507.14 EIM80479.1 - 2.6e-39 134.8 0.0 3.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Abhydrolase_1 PF00561.15 EIM80480.1 - 2.9e-14 53.1 0.0 4.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM80480.1 - 1.3e-10 41.5 0.0 1.9e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80480.1 - 0.011 15.4 0.0 0.15 11.8 0.0 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family LRR_6 PF13516.1 EIM80482.1 - 3.2e-12 45.1 4.4 0.0003 20.5 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 EIM80482.1 - 3.6e-10 39.2 4.6 0.00093 18.7 0.1 4.3 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM80482.1 - 0.00058 19.5 5.5 4.6 7.6 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EIM80482.1 - 0.003 17.4 6.8 8.3 7.1 0.1 5.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 EIM80482.1 - 0.004 16.8 4.3 1 9.1 1.7 3.1 2 1 1 3 3 3 2 Leucine rich repeat SH3_1 PF00018.23 EIM80485.1 - 2.7e-18 65.0 2.8 1e-08 34.4 0.2 3.6 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIM80485.1 - 4e-13 48.7 6.7 8.6e-07 28.4 0.3 3.4 3 1 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EIM80485.1 - 6.7e-12 44.7 0.8 7e-08 31.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.12 EIM80485.1 - 3e-11 42.9 0.3 8.4e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 EIM80485.1 - 1.7e-10 41.2 0.2 5.4e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EIM80485.1 - 6.7e-08 32.5 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.6 EIM80485.1 - 0.0015 18.6 6.7 0.034 14.3 0.8 2.8 3 0 0 3 3 3 2 Bacterial SH3 domain PX PF00787.19 EIM80488.1 - 2.1e-21 75.8 0.0 8.4e-21 73.8 0.0 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EIM80488.1 - 5.5e-05 22.5 6.7 0.0046 16.2 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 EIM80488.1 - 0.037 13.3 1.3 0.053 12.8 0.1 1.8 2 0 0 2 2 2 0 FAM92 protein DUF4391 PF14335.1 EIM80488.1 - 0.038 13.3 0.5 0.085 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) zf-C3HC4_2 PF13923.1 EIM80490.1 - 8.6e-12 44.8 8.4 1.8e-11 43.8 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM80490.1 - 2.6e-10 39.9 8.8 2.6e-10 39.9 6.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM80490.1 - 1.6e-09 37.2 6.6 2.1e-09 36.9 3.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM80490.1 - 2.6e-07 30.1 8.4 5.8e-07 29.0 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM80490.1 - 7.5e-07 28.9 8.2 1.7e-06 27.7 5.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM80490.1 - 1.2e-06 28.1 6.3 3.1e-06 26.7 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIM80490.1 - 4e-06 26.4 1.7 4e-06 26.4 1.2 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIM80490.1 - 0.035 13.8 3.3 0.094 12.5 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EIM80490.1 - 0.037 13.6 6.8 0.078 12.5 4.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2937 PF11157.3 EIM80490.1 - 0.063 12.6 0.5 0.099 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ADIP PF11559.3 EIM80490.1 - 0.087 12.7 3.9 0.17 11.8 2.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rtf2 PF04641.7 EIM80490.1 - 0.22 10.7 1.6 0.48 9.5 1.1 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger DivIC PF04977.10 EIM80490.1 - 0.66 9.5 2.8 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator zinc_ribbon_5 PF13719.1 EIM80490.1 - 4.2 7.0 6.0 23 4.6 1.8 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM80490.1 - 8 6.2 6.5 13 5.5 0.2 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EIM80491.1 - 4.2e-11 42.6 9.0 7e-11 41.9 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM80491.1 - 7e-11 41.7 6.9 1.1e-10 41.1 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM80491.1 - 4.7e-10 38.9 6.7 7.5e-10 38.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM80491.1 - 2.9e-09 36.4 8.6 4.9e-09 35.7 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM80491.1 - 2.9e-09 36.6 10.1 5.1e-09 35.8 7.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM80491.1 - 1.3e-08 34.3 6.8 2.4e-08 33.5 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIM80491.1 - 1.3e-06 28.0 4.3 2.9e-06 26.8 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIM80491.1 - 3.9e-05 23.3 3.4 9.3e-05 22.1 2.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Nup54 PF13874.1 EIM80491.1 - 0.0021 17.7 0.3 0.0044 16.6 0.2 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 BLOC1_2 PF10046.4 EIM80491.1 - 0.0051 16.9 1.4 2.5 8.2 0.0 2.2 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 EIM80491.1 - 0.0093 15.4 1.0 0.013 15.0 0.7 1.1 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.4 EIM80491.1 - 0.0097 14.8 1.9 0.014 14.3 1.4 1.4 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EIM80491.1 - 0.015 15.2 3.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor zf-Apc11 PF12861.2 EIM80491.1 - 0.018 14.8 1.4 0.032 14.0 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EIM80491.1 - 0.035 14.0 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 EIM80491.1 - 0.045 13.8 3.8 0.11 12.6 2.1 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger CHASE3 PF05227.8 EIM80491.1 - 0.072 12.7 0.5 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 CHASE3 domain zf-MIZ PF02891.15 EIM80491.1 - 0.074 12.5 6.3 0.13 11.7 4.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EIM80491.1 - 0.079 12.5 7.3 0.22 11.1 5.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EIM80491.1 - 0.12 11.9 5.7 0.25 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.1 EIM80491.1 - 0.39 10.3 0.1 0.39 10.3 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM80491.1 - 0.56 9.9 0.1 0.56 9.9 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain SlyX PF04102.7 EIM80491.1 - 1.3 9.4 3.8 1.8 8.9 0.1 2.4 1 1 1 2 2 2 0 SlyX FYVE PF01363.16 EIM80491.1 - 8.5 6.3 7.5 9 6.2 2.5 2.6 2 1 1 3 3 3 0 FYVE zinc finger Reo_sigmaC PF04582.7 EIM80492.1 - 0.048 12.8 8.6 1.4 8.0 0.1 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliJ PF02050.11 EIM80492.1 - 0.094 12.7 38.2 0.27 11.2 8.5 4.4 2 1 2 4 4 4 0 Flagellar FliJ protein DUF3584 PF12128.3 EIM80492.1 - 0.15 9.3 32.2 0.25 8.6 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EIM80492.1 - 0.7 9.4 47.9 7.8 6.0 4.3 4.1 2 1 1 3 3 3 0 IncA protein Tox-MPTase2 PF15638.1 EIM80492.1 - 1 8.8 3.9 0.94 8.9 0.8 2.1 2 0 0 2 2 2 0 Metallopeptidase toxin 2 COG5 PF10392.4 EIM80492.1 - 1.4 8.9 19.8 0.6 10.0 1.2 3.2 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Flu_NS2 PF00601.14 EIM80492.1 - 6.7 6.9 14.5 1.2 9.3 0.5 4.1 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) NMO PF03060.10 EIM80493.1 - 7.8e-68 229.0 4.6 9.4e-68 228.7 3.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIM80493.1 - 5.1e-06 25.6 0.3 0.0011 17.9 0.2 3.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIM80493.1 - 1.7 7.3 5.8 2.6 6.8 4.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PS_Dcarbxylase PF02666.10 EIM80495.1 - 7.2e-39 133.1 0.0 9e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EIM80495.1 - 7.5e-35 119.6 0.0 1.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Oxidored_FMN PF00724.15 EIM80496.1 - 5.5e-72 242.6 0.0 7.3e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SAC3_GANP PF03399.11 EIM80497.1 - 1.7e-56 190.9 0.3 3.2e-56 190.1 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIM80497.1 - 1.8e-08 34.2 0.2 6.2e-08 32.5 0.2 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EIM80497.1 - 0.027 14.7 0.0 0.096 13.0 0.0 2.0 1 0 0 1 1 1 0 PCI domain DUF1510 PF07423.6 EIM80498.1 - 0.41 9.9 9.9 0.5 9.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 EIM80498.1 - 0.47 9.9 12.7 0.5 9.8 8.8 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 EIM80498.1 - 1.3 8.2 10.2 1.6 7.9 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EIM80498.1 - 2 6.2 16.9 2.3 6.0 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIM80498.1 - 2.3 6.1 11.7 2.7 5.9 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DASH_Hsk3 PF08227.6 EIM80500.1 - 2.3e-05 24.4 1.9 3.2e-05 24.0 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SDH_alpha PF03313.10 EIM80501.1 - 1.6e-92 309.5 1.8 2.9e-92 308.7 1.3 1.4 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EIM80501.1 - 1.3e-52 178.0 0.0 2.3e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Velvet PF11754.3 EIM80502.1 - 3e-23 82.5 0.0 5e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Velvet factor TPR_11 PF13414.1 EIM80503.1 - 6.6e-23 80.1 3.4 5.7e-11 41.9 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIM80503.1 - 2e-17 61.9 0.9 2.4e-07 30.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80503.1 - 2e-16 59.6 5.9 2.5e-07 30.5 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80503.1 - 6.8e-16 56.8 2.1 7.1e-07 28.6 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM80503.1 - 1.8e-12 46.4 0.1 0.0087 16.1 0.0 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM80503.1 - 3.7e-12 46.5 1.3 8.3e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM80503.1 - 8.3e-12 43.9 0.5 0.00065 19.2 0.0 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM80503.1 - 2.2e-11 43.3 1.9 0.00098 19.5 0.0 4.1 2 2 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM80503.1 - 1.8e-09 37.7 0.2 5.8e-05 23.3 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM80503.1 - 1.9e-06 27.2 4.5 0.011 15.4 0.0 3.6 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM80503.1 - 5.7e-06 26.0 4.0 0.082 12.8 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM80503.1 - 3.4e-05 23.9 1.2 0.053 13.6 0.1 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIM80503.1 - 4.2e-05 22.7 0.2 5.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM80503.1 - 6.1e-05 23.2 0.1 0.093 13.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc5 PF12862.2 EIM80503.1 - 0.00053 19.7 0.3 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_9 PF13371.1 EIM80503.1 - 0.0011 18.7 1.0 1.3 8.9 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 EIM80503.1 - 0.0038 17.0 2.1 4.5 7.2 0.1 3.3 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EIM80503.1 - 0.0041 17.3 0.5 0.0041 17.3 0.3 3.3 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIM80503.1 - 0.0098 15.9 2.3 0.045 13.8 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EIM80503.1 - 0.013 14.2 0.8 0.11 11.2 0.1 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 EIM80503.1 - 0.019 14.8 0.5 7.8 6.3 0.0 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 EIM80503.1 - 0.054 13.5 0.2 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat HCMVantigenic_N PF12154.3 EIM80503.1 - 2.7 7.9 5.4 0.64 9.9 0.9 2.1 2 0 0 2 2 1 0 Glycoprotein B N-terminal antigenic domain of HCMV FAD_binding_3 PF01494.14 EIM80504.1 - 1.7e-22 80.0 0.0 5.3e-22 78.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EIM80504.1 - 5.9e-07 28.4 0.1 2.5e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EIM80504.1 - 0.00089 19.2 1.5 0.0021 18.0 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM80504.1 - 0.0055 15.2 1.7 0.0079 14.7 1.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EIM80504.1 - 0.016 14.1 3.8 0.2 10.5 2.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIM80504.1 - 0.022 13.8 1.3 0.039 13.0 0.9 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EIM80504.1 - 0.031 13.3 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM80504.1 - 0.063 13.6 1.6 0.18 12.1 1.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM80504.1 - 0.1 12.3 1.4 4.2 7.1 0.7 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIM80504.1 - 0.11 12.1 1.1 0.99 8.9 0.4 2.2 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EIM80504.1 - 0.16 11.8 2.4 0.33 10.7 1.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM80504.1 - 0.17 10.7 2.0 0.29 9.9 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EIM80504.1 - 0.23 10.2 1.0 0.32 9.8 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Cytochrom_C1 PF02167.10 EIM80505.1 - 7.5e-85 284.0 0.0 9.2e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EIM80505.1 - 0.00034 20.6 0.0 0.00071 19.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EIM80505.1 - 0.032 15.0 1.0 0.047 14.5 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c CYSTM PF12734.2 EIM80506.1 - 6.1e-09 35.8 16.1 6.1e-09 35.8 11.2 5.0 2 2 1 3 3 3 1 Cysteine-rich TM module stress tolerance CCER1 PF15482.1 EIM80506.1 - 1.9 8.0 8.1 2.1 7.9 5.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 RCR PF12273.3 EIM80506.1 - 3.3 8.2 19.4 4.3 7.9 13.4 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red UAA PF08449.6 EIM80509.1 - 7.4e-15 54.6 19.7 9.7e-15 54.2 13.7 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIM80509.1 - 5.8e-10 39.0 3.5 5.8e-10 39.0 2.4 3.0 1 1 0 2 2 2 1 Triose-phosphate Transporter family CPSase_L_D2 PF02786.12 EIM80510.1 - 1.7e-79 265.9 0.1 3.9e-79 264.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EIM80510.1 - 6.1e-67 224.8 0.0 1.2e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EIM80510.1 - 9.1e-37 125.5 0.1 2.3e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIM80510.1 - 1.2e-29 102.4 0.0 3.9e-29 100.7 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EIM80510.1 - 3.1e-29 102.3 0.0 6.4e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EIM80510.1 - 1.6e-19 69.3 6.9 1.5e-17 63.0 2.1 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIM80510.1 - 1.4e-18 67.2 0.1 2.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIM80510.1 - 1.1e-16 60.4 0.0 8.9e-16 57.5 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EIM80510.1 - 1.5e-13 50.1 5.1 1.2e-07 31.3 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EIM80510.1 - 1.7e-10 40.6 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 EIM80510.1 - 4.5e-08 32.7 3.7 0.00052 19.4 0.1 2.8 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 EIM80510.1 - 7e-07 29.5 0.5 0.034 14.4 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 EIM80510.1 - 1.7e-06 27.4 0.0 3.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EIM80510.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.14 EIM80510.1 - 0.00024 20.7 2.4 0.0014 18.3 0.5 3.1 3 1 1 4 4 4 1 Glycine cleavage H-protein RimK PF08443.6 EIM80510.1 - 0.00069 19.1 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 EIM80510.1 - 0.0014 17.9 0.4 0.0029 16.8 0.2 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) AP_endonuc_2 PF01261.19 EIM80510.1 - 0.0017 17.6 0.0 0.12 11.6 0.0 2.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel HlyD_2 PF12700.2 EIM80510.1 - 0.0032 16.6 0.2 0.21 10.7 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 EIM80510.1 - 0.0063 16.2 1.8 0.021 14.5 0.7 2.3 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 EIM80510.1 - 0.033 13.9 0.1 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 EIM80510.1 - 0.045 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PNPase PF03726.9 EIM80510.1 - 0.11 12.8 0.2 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain LSM PF01423.17 EIM80511.1 - 2.5e-15 55.7 0.0 3.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ecl1 PF12855.2 EIM80513.1 - 2.7e-05 23.3 2.5 4.8e-05 22.5 1.7 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Pol_alpha_B_N PF08418.5 EIM80513.1 - 5 6.5 8.5 6.9 6.1 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SHR3_chaperone PF08229.6 EIM80514.1 - 3.8e-30 104.3 0.2 4.1e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RhoGAP PF00620.22 EIM80515.1 - 2.8e-41 140.6 0.0 6.1e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EIM80515.1 - 1.6e-12 47.5 0.0 3.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EIM80515.1 - 4.6e-08 33.2 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 EIM80515.1 - 5.8e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_8 PF15409.1 EIM80515.1 - 0.01 15.9 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PH_7 PF15408.1 EIM80515.1 - 0.076 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain IncA PF04156.9 EIM80515.1 - 0.19 11.2 0.1 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 EIM80516.1 - 1.7e-51 173.8 0.0 2.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM80516.1 - 2.2e-15 57.2 0.0 2.9e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM80516.1 - 1.2e-07 31.1 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM80516.1 - 0.00077 18.7 0.0 0.0019 17.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIM80516.1 - 0.0022 17.2 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM80516.1 - 0.0046 16.9 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Fungal_trans PF04082.13 EIM80517.1 - 1.3e-19 70.0 0.0 3.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80517.1 - 1.2e-05 25.1 10.1 2.3e-05 24.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.8 EIM80518.1 - 4.8e-34 117.3 0.1 4.8e-34 117.3 0.1 2.4 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain DUF1771 PF08590.5 EIM80519.1 - 3.2e-12 46.2 6.3 6.3e-12 45.3 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EIM80519.1 - 1.4e-06 27.8 7.4 0.0044 16.6 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EIM80519.1 - 3.9e-05 23.7 0.2 0.00011 22.3 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.4 EIM80519.1 - 0.19 11.2 3.0 11 5.6 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 EIM80519.1 - 8.9 6.4 6.8 5.1 7.2 0.5 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type EIF_2_alpha PF07541.7 EIM80520.1 - 1.6e-36 124.5 0.0 2.8e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EIM80520.1 - 5e-13 48.9 0.8 8.1e-13 48.2 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain EF-hand_9 PF14658.1 EIM80520.1 - 0.033 14.0 0.1 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain IncA PF04156.9 EIM80521.1 - 0.00015 21.4 14.3 0.014 14.9 4.4 2.1 2 0 0 2 2 2 2 IncA protein Rab5-bind PF09311.6 EIM80521.1 - 0.00018 21.4 9.2 0.0083 16.0 0.0 2.4 2 0 0 2 2 2 1 Rabaptin-like protein FH2 PF02181.18 EIM80521.1 - 0.00046 19.1 8.0 0.0063 15.4 0.1 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Atg14 PF10186.4 EIM80521.1 - 0.0039 16.1 8.5 0.034 13.1 1.5 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 EIM80521.1 - 0.01 14.9 15.1 0.01 14.9 10.4 2.1 2 0 0 2 2 2 0 Tropomyosin Fusion_gly PF00523.13 EIM80521.1 - 0.047 11.7 0.0 0.074 11.0 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Fez1 PF06818.10 EIM80521.1 - 0.058 13.4 9.7 0.92 9.4 2.3 2.2 2 0 0 2 2 2 0 Fez1 Rootletin PF15035.1 EIM80521.1 - 0.097 12.6 15.2 0.12 12.3 6.8 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EIM80521.1 - 0.14 11.3 3.9 4.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 EIM80521.1 - 0.36 9.2 7.2 5.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family ATG16 PF08614.6 EIM80521.1 - 0.36 10.6 17.1 0.5 10.1 7.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 EIM80521.1 - 0.38 10.0 23.3 0.62 9.3 11.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 EIM80521.1 - 0.43 10.9 8.7 6.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2407_C PF13373.1 EIM80521.1 - 0.44 10.4 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain TMF_DNA_bd PF12329.3 EIM80521.1 - 0.52 10.1 26.3 0.18 11.6 2.2 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Uds1 PF15456.1 EIM80521.1 - 0.57 10.1 19.0 0.21 11.5 0.3 3.1 2 1 1 3 3 3 0 Up-regulated During Septation DUF4140 PF13600.1 EIM80521.1 - 0.77 10.2 17.0 1.6 9.1 0.2 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 EIM80521.1 - 0.8 8.8 12.9 2.5 7.2 5.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIM80521.1 - 0.84 8.6 16.3 0.42 9.6 5.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EIM80521.1 - 0.84 9.5 15.5 1.5 8.7 6.1 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like ADIP PF11559.3 EIM80521.1 - 0.96 9.3 15.5 2.6 7.9 5.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF87 PF01935.12 EIM80521.1 - 1.1 8.9 3.2 1.3 8.7 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Spc7 PF08317.6 EIM80521.1 - 1.2 7.7 13.7 0.33 9.5 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.3 EIM80521.1 - 1.8 5.8 14.1 2.9 5.0 6.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 EIM80521.1 - 1.9 8.3 22.9 3.7 7.4 1.1 2.2 2 0 0 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.7 EIM80521.1 - 2.3 7.9 18.2 2.3 7.9 1.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 EIM80521.1 - 2.5 8.1 16.2 5.1 7.1 5.4 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.1 EIM80521.1 - 2.8 7.3 14.5 17 4.8 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.1 EIM80521.1 - 3.1 6.6 10.5 2.6 6.9 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.4 EIM80521.1 - 3.3 7.5 21.3 2.2 8.1 0.7 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EIM80521.1 - 4.4 7.0 17.8 4.2 7.1 5.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HlyD PF00529.15 EIM80521.1 - 5.4 6.2 14.8 1.5 8.0 5.9 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Mnd1 PF03962.10 EIM80521.1 - 5.4 6.6 14.5 7.2 6.2 5.1 2.1 2 0 0 2 2 2 0 Mnd1 family GBP_C PF02841.9 EIM80521.1 - 6.3 5.8 16.1 1.1 8.3 6.6 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain PEP-utilisers_N PF05524.8 EIM80521.1 - 7 6.4 15.7 0.15 11.8 0.3 2.8 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Phage_GP20 PF06810.6 EIM80521.1 - 7.9 5.8 10.3 4.6 6.6 0.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fungal_trans PF04082.13 EIM80522.1 - 8.4e-16 57.6 0.5 1.5e-15 56.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80522.1 - 0.00014 21.7 8.4 0.00025 20.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clathrin PF00637.15 EIM80523.1 - 1.6e-209 685.8 30.5 2.1e-32 111.6 1.2 7.6 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EIM80523.1 - 3.2e-30 102.3 0.5 5.8e-05 23.1 0.0 7.3 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 EIM80523.1 - 3.7e-30 103.6 0.1 1.2e-29 102.0 0.1 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EIM80523.1 - 7.5e-09 34.4 0.3 2.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Vps39_1 PF10366.4 EIM80523.1 - 0.00012 22.0 6.7 1 9.4 0.2 5.8 5 1 0 5 5 5 2 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.9 EIM80523.1 - 0.00034 19.5 7.0 1.2 7.8 0.0 4.7 4 1 1 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.23 EIM80523.1 - 0.0062 16.0 4.7 19 5.0 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM80523.1 - 0.036 13.9 7.6 10 6.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM80523.1 - 0.14 12.8 14.8 12 6.8 0.1 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM80523.1 - 0.26 11.1 11.7 5 7.1 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80523.1 - 0.41 10.6 14.5 1.3 9.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80523.1 - 3 7.9 13.8 59 3.9 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat APH PF01636.18 EIM80524.1 - 2.6e-08 33.8 0.0 6.8e-07 29.2 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM80524.1 - 0.069 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EIM80524.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Tri3 PF07428.6 EIM80524.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 DUF2665 PF11654.3 EIM80524.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) NIR_SIR PF01077.17 EIM80525.1 - 1.5e-51 173.8 0.0 9.4e-45 151.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EIM80525.1 - 3.1e-32 110.0 0.0 7.8e-15 54.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EIM80525.1 - 1.4e-28 99.6 0.1 2.9e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EIM80525.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Cation_efflux PF01545.16 EIM80526.1 - 4.9e-59 199.7 14.9 3.3e-58 197.0 10.3 2.4 1 1 0 1 1 1 1 Cation efflux family CASP_C PF08172.7 EIM80526.1 - 0.085 11.8 0.5 0.15 11.0 0.3 1.3 1 0 0 1 1 1 0 CASP C terminal Rcd1 PF04078.8 EIM80527.1 - 3e-129 429.4 2.0 3.4e-129 429.3 1.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cofilin_ADF PF00241.15 EIM80528.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.24 EIM80528.1 - 0.00037 20.6 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Borrelia_P83 PF05262.6 EIM80528.1 - 0.024 12.9 14.8 0.027 12.7 10.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 EIM80528.1 - 7.1 5.6 9.3 9.9 5.1 6.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mus7 PF09462.5 EIM80529.1 - 6.8e-44 150.7 1.0 2.5e-43 148.8 0.1 2.0 2 0 0 2 2 2 1 Mus7/MMS22 family PQ-loop PF04193.9 EIM80530.1 - 8.8e-17 60.4 2.6 1.6e-10 40.3 0.6 2.8 2 0 0 2 2 2 2 PQ loop repeat Dimer_Tnp_hAT PF05699.9 EIM80532.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF563 PF04577.9 EIM80533.1 - 5.9e-20 72.0 0.3 1.3e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) IGPS PF00218.16 EIM80535.1 - 3e-95 318.0 0.1 4.5e-95 317.5 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EIM80535.1 - 2.7e-59 200.0 0.0 9.7e-54 181.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EIM80535.1 - 4e-46 156.9 0.0 8.4e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIM80535.1 - 1.5e-06 27.8 0.0 3.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EIM80535.1 - 0.00039 19.9 0.8 0.0036 16.8 0.2 2.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain HAD PF12710.2 EIM80536.1 - 2.4e-20 73.5 0.0 1.1e-19 71.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIM80536.1 - 1.9e-19 69.6 0.0 3.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIM80536.1 - 1.7e-14 54.7 1.6 7e-13 49.4 1.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM80536.1 - 7.1e-12 45.1 0.0 2.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIM80536.1 - 0.002 17.7 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM80536.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.15 EIM80537.1 - 1.3e-09 37.9 0.0 2.5e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM80537.1 - 5.3e-07 29.4 0.0 2.3e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM80537.1 - 1.3e-06 28.4 0.0 3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIM80537.1 - 0.0076 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EIM80537.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DPBB_1 PF03330.13 EIM80538.1 - 4.3e-11 42.6 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EIM80538.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.3 1 1 0 1 1 1 0 Cerato-platanin DUF4473 PF14747.1 EIM80538.1 - 0.025 14.7 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Barwin PF00967.12 EIM80538.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Barwin family PB1 PF00564.19 EIM80539.1 - 7.2e-14 51.2 0.0 1.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EIM80539.1 - 1.7e-10 40.4 9.4 2.1e-07 30.4 0.2 4.2 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EIM80539.1 - 4.2e-10 38.7 4.9 0.0015 18.0 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80539.1 - 2.7e-08 33.6 1.4 0.0018 18.1 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM80539.1 - 1.6e-07 30.6 2.7 0.023 14.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80539.1 - 1.8e-07 30.5 7.2 0.0049 16.6 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM80539.1 - 0.0013 18.3 0.9 0.17 11.7 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM80539.1 - 0.03 14.4 0.9 1.9 8.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM80539.1 - 0.68 10.5 5.0 74 4.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM80539.1 - 5.5 7.7 8.3 7.6 7.3 0.8 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat IGPD PF00475.13 EIM80540.1 - 1.4e-60 203.3 0.2 1.8e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase GIT_SHD PF08518.6 EIM80541.1 - 4e-23 80.4 15.5 1.4e-14 53.1 1.2 3.5 4 0 0 4 4 4 2 Spa2 homology domain (SHD) of GIT TPR_12 PF13424.1 EIM80541.1 - 0.67 9.9 4.4 0.23 11.3 0.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 EIM80541.1 - 1 9.2 25.4 1.3 8.8 10.4 3.9 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding LCD1 PF09798.4 EIM80541.1 - 1.4 6.8 6.7 2.6 5.9 4.6 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein TBPIP PF07106.8 EIM80541.1 - 6.9 6.1 13.3 8 5.9 0.3 2.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Abhydro_lipase PF04083.11 EIM80542.1 - 2.1e-21 75.0 0.0 4e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EIM80542.1 - 6.7e-17 61.8 1.5 1.9e-16 60.3 1.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM80542.1 - 1.2e-07 31.8 0.6 3e-07 30.5 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80542.1 - 0.00014 21.6 0.0 0.0012 18.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIM80542.1 - 0.0055 16.1 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) HARP PF07443.8 EIM80542.1 - 0.26 10.6 1.2 0.59 9.5 0.8 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) p450 PF00067.17 EIM80543.1 - 3.6e-24 85.1 0.0 3.8e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 EIM80544.1 - 2.6e-26 92.2 0.0 4.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM80544.1 - 2.2e-09 37.0 0.0 5.9e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM80544.1 - 0.00075 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TP_methylase PF00590.15 EIM80545.1 - 2.5e-17 63.3 0.0 4.1e-17 62.6 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 EIM80545.1 - 0.14 11.9 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) tRNA-synt_2 PF00152.15 EIM80546.1 - 3.4e-70 236.4 0.0 5e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIM80546.1 - 9.7e-11 41.3 0.1 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FMN_red PF03358.10 EIM80546.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Ribosomal_S25 PF03297.10 EIM80546.1 - 0.4 10.7 3.8 1 9.4 2.6 1.6 1 0 0 1 1 1 0 S25 ribosomal protein Glyco_hydro_28 PF00295.12 EIM80548.1 - 5.3e-57 193.2 15.0 7.6e-57 192.7 10.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.17 EIM80550.1 - 1.5e-51 175.4 0.0 1.7e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80551.1 - 1.5e-09 36.8 0.0 1.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDUF_B12 PF08122.7 EIM80551.1 - 0.038 13.7 0.7 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4098 PF13345.1 EIM80554.1 - 0.00021 21.1 3.2 0.36 10.8 0.0 3.5 3 1 0 3 3 3 3 Domain of unknown function (DUF4098) BTB PF00651.26 EIM80557.1 - 3.4e-07 30.2 0.0 5.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Clathrin_lg_ch PF01086.12 EIM80558.1 - 5e-37 128.0 3.2 6.9e-37 127.5 2.2 1.2 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.1 EIM80558.1 - 0.059 12.3 6.4 0.075 11.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.3 EIM80558.1 - 0.084 10.1 7.1 0.098 9.9 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RR_TM4-6 PF06459.7 EIM80558.1 - 0.097 12.5 3.7 0.13 12.1 2.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRF PF01765.14 EIM80558.1 - 0.62 9.5 10.5 1.1 8.6 7.3 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF4337 PF14235.1 EIM80558.1 - 5.9 6.7 7.2 9 6.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2263 PF10021.4 EIM80559.1 - 1.8e-32 112.4 0.1 4.4e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Abhydrolase_6 PF12697.2 EIM80560.1 - 1e-19 71.3 0.0 1.3e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM80560.1 - 9.5e-19 67.0 0.2 6.7e-18 64.3 0.1 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EIM80560.1 - 1.5e-18 66.9 0.0 2.6e-18 66.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM80560.1 - 2.7e-05 23.4 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EIM80560.1 - 3.7e-05 23.3 0.3 0.00089 18.8 0.2 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EIM80560.1 - 0.00044 18.8 0.9 0.17 10.3 0.2 2.8 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) DUF1749 PF08538.5 EIM80560.1 - 0.00064 18.7 0.1 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 EIM80560.1 - 0.00096 18.6 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EIM80560.1 - 0.00097 18.7 0.0 0.0026 17.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EIM80560.1 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EIM80560.1 - 0.0075 15.8 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 EIM80560.1 - 0.014 14.6 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EIM80560.1 - 0.017 14.6 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EIM80560.1 - 0.047 12.5 0.5 1.3 7.8 0.3 2.4 2 1 0 2 2 2 0 Chlorophyllase enzyme DUF915 PF06028.6 EIM80560.1 - 0.085 11.9 0.0 5 6.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.13 EIM80560.1 - 0.11 11.9 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Meckelin PF09773.4 EIM80560.1 - 0.21 9.3 0.0 0.29 8.8 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) F-box-like PF12937.2 EIM80561.1 - 1e-11 44.3 1.9 9.1e-11 41.3 0.5 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM80561.1 - 0.039 13.5 3.0 14 5.4 0.1 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EIM80561.1 - 0.048 13.3 3.8 6.4 6.5 0.1 3.6 3 0 0 3 3 3 0 F-box domain PGP_phosphatase PF09419.5 EIM80562.1 - 5.1e-46 156.1 0.0 6.8e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EIM80562.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_hydro_10 PF00331.15 EIM80563.1 - 7e-98 327.5 0.8 8.2e-98 327.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EIM80563.1 - 8e-13 47.8 12.8 8e-13 47.8 8.9 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Cellulase-like PF12876.2 EIM80563.1 - 0.013 15.9 0.0 0.042 14.2 0.0 1.8 1 1 0 1 1 1 0 Sugar-binding cellulase-like HNH_2 PF13391.1 EIM80564.1 - 0.00024 20.8 0.0 0.00063 19.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease GST_N_3 PF13417.1 EIM80566.1 - 2.4e-23 82.1 0.0 6.5e-23 80.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM80566.1 - 1.6e-17 63.2 0.0 3.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM80566.1 - 2.4e-08 34.0 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM80566.1 - 1.5e-06 28.0 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM80566.1 - 0.00025 20.9 0.0 0.0006 19.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM80566.1 - 0.0009 19.6 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4455 PF14643.1 EIM80566.1 - 0.039 12.5 0.1 0.072 11.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) ARID PF01388.16 EIM80566.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Misat_Tub_SegII PF10644.4 EIM80567.1 - 2e-34 118.1 0.1 4.2e-34 117.0 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIM80567.1 - 3.6e-30 104.7 0.0 5.5e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EIM80567.1 - 1.6e-08 34.6 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sec66 PF09802.4 EIM80567.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Abhydrolase_3 PF07859.8 EIM80568.1 - 2e-36 125.5 0.0 1.1e-30 106.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM80568.1 - 5.9e-10 38.3 0.0 1.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIM80568.1 - 0.00034 20.3 0.0 0.00085 19.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1010 PF06231.6 EIM80568.1 - 1 9.4 7.6 0.093 12.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Glyco_hydro_12 PF01670.11 EIM80569.1 - 3.7e-33 114.5 2.5 5.5e-33 113.9 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Abhydrolase_3 PF07859.8 EIM80570.1 - 1.5e-48 165.2 0.0 1.8e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM80570.1 - 4.9e-06 25.5 0.4 2.1e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM80570.1 - 0.03 14.0 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIM80571.1 - 1.3e-42 145.7 0.0 2.3e-42 144.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM80571.1 - 1.5e-06 27.2 0.2 6.9e-06 25.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Foie-gras_1 PF11817.3 EIM80572.1 - 3.5e-50 170.8 0.8 2.2e-49 168.1 0.6 2.1 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.7 EIM80572.1 - 1.6e-47 162.0 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 EIM80572.1 - 5.5e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.1 EIM80572.1 - 0.00034 20.4 0.7 0.039 13.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Transglut_C PF00927.17 EIM80572.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain TPR_1 PF00515.23 EIM80572.1 - 0.021 14.4 1.0 0.047 13.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC10 PF12584.3 EIM80572.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_6 PF13174.1 EIM80572.1 - 0.031 14.7 0.7 0.12 12.8 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM80572.1 - 0.046 13.6 0.3 0.046 13.6 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM80572.1 - 0.16 11.8 0.2 0.73 9.7 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2079 PF09852.4 EIM80573.1 - 0.031 13.0 0.5 0.033 12.8 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) F-box-like PF12937.2 EIM80574.1 - 5.3e-09 35.6 0.4 1.3e-08 34.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like ABC_membrane PF00664.18 EIM80576.1 - 2.3e-50 171.5 2.2 4.2e-50 170.7 1.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIM80576.1 - 2.6e-29 102.2 0.0 6.8e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EIM80576.1 - 0.00021 20.6 1.1 0.0081 15.4 0.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM80576.1 - 0.00031 20.8 0.0 0.075 12.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM80576.1 - 0.0021 18.1 0.2 0.0069 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EIM80576.1 - 0.004 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EIM80576.1 - 0.014 14.5 0.1 0.054 12.5 0.0 2.0 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.1 EIM80576.1 - 0.034 13.6 0.4 0.098 12.2 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SUR7 PF06687.7 EIM80577.1 - 1e-14 54.5 20.5 1.5e-14 54.1 14.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family Hum_adeno_E3A PF05393.6 EIM80577.1 - 0.67 9.6 6.7 1.9 8.2 0.7 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Amastin PF07344.6 EIM80577.1 - 5.7 6.5 23.7 0.56 9.8 11.5 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein ubiquitin PF00240.18 EIM80578.1 - 6.3e-07 28.7 0.9 2e-06 27.0 0.7 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIM80578.1 - 4.3e-06 26.8 0.3 1.3e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EIM80578.1 - 0.012 15.2 0.3 0.086 12.5 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EIM80578.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HSP70 PF00012.15 EIM80579.1 - 1.7e-267 888.2 15.3 1.9e-267 888.0 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM80579.1 - 7e-16 57.7 3.1 5.3e-14 51.5 1.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EIM80579.1 - 2.1e-05 24.3 9.2 0.081 12.7 0.2 4.7 4 1 0 4 4 4 2 Cell division protein FtsA FGGY_C PF02782.11 EIM80579.1 - 0.013 15.1 0.1 0.033 13.7 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain TMEM247 PF15444.1 EIM80579.1 - 0.56 9.9 3.2 1.4 8.6 1.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 247 APH PF01636.18 EIM80580.1 - 3.9e-39 134.8 0.0 5.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIM80580.1 - 3.1e-05 23.2 0.0 5.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EIM80580.1 - 0.00036 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-TFIIB PF13453.1 EIM80581.1 - 0.0095 15.1 2.0 0.039 13.1 1.0 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger DUF2393 PF09624.5 EIM80582.1 - 0.029 13.8 0.5 0.033 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Trp_syntA PF00290.15 EIM80583.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Beta-lactamase PF00144.19 EIM80585.1 - 3.1e-41 141.4 0.3 4.8e-41 140.8 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EIM80585.1 - 0.0049 16.6 0.1 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) He_PIG_assoc PF10632.4 EIM80585.1 - 0.078 12.3 0.1 0.2 10.9 0.0 1.8 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Amidohydro_4 PF13147.1 EIM80587.1 - 3.3e-20 73.2 0.1 5.6e-20 72.5 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM80587.1 - 1e-16 61.5 0.0 6.4e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIM80587.1 - 4.8e-07 29.3 0.0 9.1e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM80587.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Beta-lactamase PF00144.19 EIM80588.1 - 2.5e-64 217.4 0.9 2.9e-64 217.1 0.6 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EIM80588.1 - 0.068 12.4 0.0 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase BtpA PF03437.10 EIM80588.1 - 0.18 11.0 0.1 5.1 6.2 0.0 2.1 1 1 1 2 2 2 0 BtpA family bZIP_1 PF00170.16 EIM80589.1 - 2.4e-09 36.9 3.7 2.4e-09 36.9 2.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIM80589.1 - 3.5e-07 29.9 6.9 3.5e-07 29.9 4.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper KIAA1430 PF13879.1 EIM80589.1 - 0.88 10.0 2.9 6.9 7.1 0.1 2.3 1 1 0 2 2 2 0 KIAA1430 homologue DivIC PF04977.10 EIM80589.1 - 0.99 8.9 3.8 4.8 6.7 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.4 EIM80589.1 - 5.8 5.0 5.2 11 4.1 3.5 1.4 1 1 0 1 1 1 0 Transmembrane protein Acyl-CoA_dh_1 PF00441.19 EIM80592.1 - 9.5e-28 97.1 0.1 1.4e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIM80592.1 - 1.8e-25 89.7 0.0 3.3e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIM80592.1 - 2.9e-20 71.5 0.1 1.9e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIM80592.1 - 2.7e-06 27.6 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_B_thumb PF14791.1 EIM80593.1 - 2.7e-23 81.4 0.0 4.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EIM80593.1 - 9e-17 61.1 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EIM80593.1 - 1.9e-09 37.5 0.0 2.7e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EIM80593.1 - 2.4e-07 30.2 0.0 5.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 EIM80593.1 - 0.00073 19.4 0.0 0.01 15.7 0.0 2.3 1 1 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.1 EIM80593.1 - 0.0025 17.9 0.0 0.009 16.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EIM80593.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.3 EIM80593.1 - 0.064 13.3 0.0 0.98 9.6 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif p450 PF00067.17 EIM80594.1 - 3.5e-65 220.3 0.0 1.5e-64 218.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 UPF0029 PF01205.14 EIM80595.1 - 3.8e-22 78.0 0.0 7.6e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pyrid_oxidase_2 PF13883.1 EIM80597.1 - 5.1e-29 101.1 0.0 7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EIM80597.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF2681 PF10883.3 EIM80598.1 - 0.39 10.9 2.9 0.92 9.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Steroid_dh PF02544.11 EIM80599.1 - 1.4e-30 106.0 1.6 3.6e-10 39.7 0.0 3.2 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIM80599.1 - 8e-08 31.8 1.0 4.3e-07 29.4 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4436 PF14494.1 EIM80600.1 - 7.5e-12 45.0 0.7 1.5e-11 44.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) GFA PF04828.9 EIM80601.1 - 8.6e-20 70.4 0.6 1.1e-19 70.1 0.4 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EIM80601.1 - 0.014 14.9 2.3 0.27 10.7 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.7 EIM80601.1 - 0.054 13.2 0.0 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cytochrom_C1 PF02167.10 EIM80601.1 - 0.067 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family zf-ribbon_3 PF13248.1 EIM80601.1 - 0.16 11.1 3.9 0.78 9.0 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIM80601.1 - 0.18 11.3 5.4 0.68 9.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EIM80601.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.1 EIM80601.1 - 0.93 9.2 8.0 0.71 9.6 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal Lipase_GDSL PF00657.17 EIM80602.1 - 6.4e-05 22.8 0.2 8.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NUDIX PF00293.23 EIM80603.1 - 1.6e-12 47.2 0.4 1.1e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain F-box-like PF12937.2 EIM80604.1 - 6.8e-14 51.3 0.3 1.9e-13 49.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM80604.1 - 0.0029 17.2 5.9 0.012 15.3 0.9 3.8 3 1 0 3 3 3 1 F-box domain Peptidase_M24 PF00557.19 EIM80605.1 - 1.1e-55 188.4 0.0 1.5e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIM80605.1 - 4.3e-18 64.9 0.0 8e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain cIII PF08134.6 EIM80605.1 - 0.37 10.4 1.3 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 cIII protein family SIS PF01380.17 EIM80606.1 - 2e-62 208.5 0.0 7e-33 113.0 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EIM80606.1 - 4.3e-25 88.1 0.3 2.4e-18 65.9 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIM80606.1 - 4.6e-20 71.9 0.0 1.5e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIM80606.1 - 1.2e-14 54.1 0.0 4.6e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIM80606.1 - 2.1e-08 33.1 0.0 3.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EIM80606.1 - 0.0073 16.0 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 SIS domain GST_C PF00043.20 EIM80607.1 - 1.5e-08 34.5 0.0 2.8e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM80607.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM80607.1 - 1.2e-06 28.5 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM80607.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM80607.1 - 0.0044 16.8 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CBF PF03914.12 EIM80608.1 - 3.7e-30 104.5 0.0 3.7e-30 104.5 0.0 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.15 EIM80608.1 - 0.013 13.9 0.0 0.32 9.2 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region MIP-T3 PF10243.4 EIM80608.1 - 0.29 9.5 40.2 0.069 11.6 15.3 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 FAD_binding_3 PF01494.14 EIM80609.1 - 5.2e-16 58.6 0.0 8.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM80609.1 - 1.5e-08 33.9 1.4 3.7e-05 22.7 1.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM80609.1 - 1.9e-06 27.8 0.8 1.9e-06 27.8 0.6 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM80609.1 - 0.00026 20.9 1.1 0.0015 18.4 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM80609.1 - 0.00037 19.5 0.4 0.16 10.8 0.6 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM80609.1 - 0.00057 18.6 1.9 0.23 10.0 1.0 2.3 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EIM80609.1 - 0.0007 19.9 0.2 0.0078 16.5 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM80609.1 - 0.00071 18.5 4.2 0.0011 17.8 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EIM80609.1 - 0.0042 16.2 1.4 0.0076 15.3 1.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIM80609.1 - 0.0076 14.7 1.0 0.018 13.5 0.8 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM80609.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM80609.1 - 0.013 14.6 0.4 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EIM80609.1 - 0.039 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EIM80609.1 - 0.16 11.4 0.3 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EIM80609.1 - 0.17 10.6 3.6 0.29 9.9 2.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIM80609.1 - 0.36 10.4 1.1 0.63 9.6 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.9 EIM80611.1 - 1.1e-35 123.1 0.1 1.4e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EIM80611.1 - 6.3e-05 22.4 0.7 0.15 11.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain FYVE_2 PF02318.11 EIM80612.1 - 0.94 9.3 12.4 0.82 9.5 1.6 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.16 EIM80612.1 - 3.2 7.7 15.4 2.4 8.1 0.6 2.7 2 1 0 2 2 2 0 FYVE zinc finger GMC_oxred_N PF00732.14 EIM80613.1 - 2.5e-61 207.4 0.0 4e-33 114.8 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM80613.1 - 1.6e-40 138.7 0.0 2.6e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM80613.1 - 0.00033 19.6 0.0 0.00095 18.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM80613.1 - 0.0013 18.6 1.2 0.0049 16.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM80613.1 - 0.018 14.0 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EIM80613.1 - 0.068 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ENTH PF01417.15 EIM80614.1 - 6.3e-52 174.6 0.1 1.3e-51 173.7 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIM80614.1 - 0.00011 20.9 0.0 0.00011 20.9 0.0 2.1 2 0 0 2 2 2 1 ANTH domain PIG-X PF08320.7 EIM80615.1 - 2.3e-27 95.6 0.0 3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 PCI PF01399.22 EIM80616.1 - 2e-09 37.6 5.4 5.8e-08 33.0 0.0 3.8 4 0 0 4 4 4 2 PCI domain Glyco_hydro_16 PF00722.16 EIM80617.1 - 7.5e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Lipase_GDSL PF00657.17 EIM80618.1 - 6.2e-08 32.7 0.2 2e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SDA1 PF05285.7 EIM80619.1 - 2.6e-84 283.3 26.6 1.1e-82 277.9 14.9 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EIM80619.1 - 1.3e-23 83.0 0.1 1.9e-22 79.3 0.0 2.6 2 0 0 2 2 2 1 NUC130/3NT domain SEP PF08059.8 EIM80620.1 - 1.6e-25 89.2 0.0 3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EIM80620.1 - 1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain Methyltransf_2 PF00891.13 EIM80621.1 - 3.2e-30 105.1 0.0 7.8e-30 103.8 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EIM80621.1 - 0.0021 17.8 1.4 0.003 17.3 0.1 2.0 2 0 0 2 2 2 1 Dimerisation domain RPA_C PF08784.6 EIM80621.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Sugar_tr PF00083.19 EIM80623.1 - 8.9e-123 410.1 23.5 1e-122 410.0 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM80623.1 - 1.7e-16 59.9 43.5 1.7e-10 40.1 15.1 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily Nucleoplasmin PF03066.10 EIM80624.1 - 0.25 10.8 5.7 0.35 10.3 3.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin p450 PF00067.17 EIM80625.1 - 1.1e-51 175.7 0.0 1.7e-50 171.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIM80626.1 - 1.4e-05 24.6 0.3 3.5e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM80626.1 - 0.0019 17.8 1.8 0.0019 17.8 1.3 2.7 3 1 0 3 3 3 1 F-box domain Kdo PF06293.9 EIM80627.1 - 5.5e-08 32.1 0.0 1.8e-06 27.2 0.0 2.3 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIM80627.1 - 0.00015 21.0 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EIM80627.1 - 0.00056 19.1 0.0 0.00074 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM80627.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM80627.1 - 0.034 13.5 0.0 0.96 8.7 0.0 2.2 1 1 1 2 2 2 0 RIO1 family DUF755 PF05501.6 EIM80629.1 - 0.14 12.2 11.8 0.3 11.1 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 EIM80629.1 - 0.3 10.5 9.3 0.46 9.9 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ion_trans PF00520.26 EIM80630.1 - 3.1e-104 346.5 78.6 1e-32 113.0 4.0 5.0 5 0 0 5 5 5 4 Ion transport protein DUF3837 PF12939.2 EIM80630.1 - 0.24 11.4 0.2 0.44 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Glyco_hydro_16 PF00722.16 EIM80631.1 - 6.9e-06 25.4 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sulfate_transp PF00916.15 EIM80632.1 - 3.5e-82 275.5 6.0 7.7e-82 274.4 4.2 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIM80632.1 - 9.9e-30 102.0 5.0 9.9e-30 102.0 3.5 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIM80632.1 - 5.3e-08 32.2 0.0 9.7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIM80632.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain Apq12 PF12716.2 EIM80632.1 - 1.3 8.7 8.9 0.46 10.2 2.9 2.9 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis ADH_zinc_N PF00107.21 EIM80633.1 - 1.1e-10 41.1 0.5 1.8e-10 40.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM80633.1 - 3.6e-06 26.7 0.0 2e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIM80633.1 - 5.9e-05 23.1 0.4 8.8e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM80633.1 - 0.0034 16.6 0.3 0.005 16.1 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family AlaDh_PNT_C PF01262.16 EIM80633.1 - 0.069 12.7 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Use1 PF09753.4 EIM80634.1 - 7e-12 45.3 0.4 2.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Membrane fusion protein Use1 Phage_lysis PF03245.8 EIM80634.1 - 0.056 13.4 3.1 0.065 13.2 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein HSBP1 PF06825.7 EIM80634.1 - 0.079 12.5 1.5 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Adeno_PIX PF03955.9 EIM80634.1 - 0.89 10.0 5.0 3.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Exonuc_VII_S PF02609.11 EIM80634.1 - 2.3 8.0 4.0 11 5.8 0.0 3.2 4 1 1 5 5 5 0 Exonuclease VII small subunit SOG2 PF10428.4 EIM80634.1 - 2.6 6.5 14.9 1.6 7.2 0.7 3.0 2 1 1 3 3 3 0 RAM signalling pathway protein polyprenyl_synt PF00348.12 EIM80635.1 - 1.3e-56 191.3 0.0 3.8e-30 104.6 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase COesterase PF00135.23 EIM80636.1 - 4.3e-101 339.2 0.0 5.4e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM80636.1 - 9.3e-07 28.6 0.0 3.5e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold SurE PF01975.12 EIM80637.1 - 1.4e-41 141.9 1.4 1.4e-41 141.9 0.9 1.3 1 1 0 1 1 1 1 Survival protein SurE DUF3371 PF11851.3 EIM80638.1 - 0.62 10.7 6.8 4.5 7.9 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) HA2 PF04408.18 EIM80639.1 - 5.8e-28 96.9 0.1 1.3e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM80639.1 - 1e-14 54.3 0.0 5.3e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM80639.1 - 6.5e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM80639.1 - 1e-07 31.6 0.1 2.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIM80639.1 - 4.4e-05 23.6 0.1 0.00021 21.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIM80639.1 - 0.00025 20.5 0.5 0.00095 18.6 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EIM80639.1 - 0.0065 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIM80639.1 - 0.0081 15.0 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EIM80639.1 - 0.037 13.8 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EIM80639.1 - 0.04 13.4 0.1 0.15 11.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EIM80639.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EIM80639.1 - 0.081 13.2 0.1 0.92 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIM80639.1 - 0.092 11.8 2.2 0.22 10.6 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin PhoH PF02562.11 EIM80639.1 - 0.095 11.9 0.1 0.48 9.6 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein Septin PF00735.13 EIM80641.1 - 5.4e-114 379.9 0.4 8.8e-114 379.2 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIM80641.1 - 8.6e-08 32.1 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM80641.1 - 1.9e-06 27.1 0.3 5.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIM80641.1 - 1.9e-06 27.4 0.1 7.2e-05 22.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIM80641.1 - 0.00045 19.7 1.4 0.035 13.5 0.2 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EIM80641.1 - 0.001 19.5 1.1 0.002 18.6 0.1 2.2 2 1 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EIM80641.1 - 0.0018 18.6 0.4 0.0093 16.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 EIM80641.1 - 0.0027 17.1 0.3 0.011 15.1 0.2 2.0 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 EIM80641.1 - 0.0027 17.5 7.2 0.18 11.6 0.1 3.2 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 EIM80641.1 - 0.0031 17.6 2.9 0.0085 16.2 0.1 2.9 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 EIM80641.1 - 0.0036 16.4 2.2 0.0074 15.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EIM80641.1 - 0.0056 16.6 0.8 0.037 14.0 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EIM80641.1 - 0.0086 15.5 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EIM80641.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIM80641.1 - 0.021 14.5 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIM80641.1 - 0.034 13.8 3.9 0.066 12.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EIM80641.1 - 0.04 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM80641.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EIM80641.1 - 0.055 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Bac_DnaA PF00308.13 EIM80641.1 - 0.074 12.6 2.2 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_33 PF13671.1 EIM80641.1 - 0.076 12.8 0.2 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EIM80641.1 - 0.087 12.3 0.7 6.3 6.2 0.0 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EIM80641.1 - 0.09 12.0 0.1 0.3 10.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B CytochromB561_N PF09786.4 EIM80641.1 - 0.096 11.1 0.4 0.18 10.2 0.2 1.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal AAA_29 PF13555.1 EIM80641.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIM80641.1 - 0.2 11.1 2.1 0.25 10.7 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EIM80641.1 - 0.33 11.1 2.3 2.1 8.5 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Myc-LZ PF02344.10 EIM80641.1 - 0.54 9.9 5.4 5.5 6.7 0.1 2.8 2 0 0 2 2 2 0 Myc leucine zipper domain Cep57_CLD_2 PF14197.1 EIM80641.1 - 1.7 8.6 10.5 0.22 11.4 3.8 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TFIIIC_sub6 PF10419.4 EIM80643.1 - 2.2e-08 33.4 0.0 3.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit FoP_duplication PF13865.1 EIM80643.1 - 1.3 9.5 11.0 2.3 8.7 7.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 API5 PF05918.6 EIM80643.1 - 9.2 4.6 7.7 12 4.2 5.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FtsJ PF01728.14 EIM80644.1 - 5e-42 143.9 0.0 6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase O-antigen_lig PF13425.1 EIM80645.1 - 0.025 14.5 3.0 0.043 13.7 1.3 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein XK-related PF09815.4 EIM80645.1 - 0.095 11.6 6.6 0.14 11.1 4.6 1.2 1 0 0 1 1 1 0 XK-related protein Glycogen_syn PF05693.8 EIM80646.1 - 0 1070.8 0.0 0 1070.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 EIM80646.1 - 5.5e-07 29.3 0.2 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIM80646.1 - 1.6e-06 27.6 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIM80646.1 - 9.3e-06 25.8 0.3 2.3e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain tRNA-synt_1b PF00579.20 EIM80647.1 - 3.4e-64 216.7 0.0 3.2e-63 213.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ank_2 PF12796.2 EIM80648.1 - 4.3e-19 68.6 0.0 1.3e-10 41.5 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIM80648.1 - 4.3e-12 45.1 2.6 0.02 14.6 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIM80648.1 - 3.9e-09 35.8 4.5 0.014 15.6 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.7 EIM80648.1 - 1e-08 34.9 0.2 4.5e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.1 EIM80648.1 - 6.6e-08 32.5 0.8 0.00086 19.4 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM80648.1 - 7.1e-08 32.7 1.7 0.23 12.0 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 EIM80648.1 - 2.7e-05 24.3 0.0 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EIM80648.1 - 0.0002 20.3 0.0 0.00045 19.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EIM80648.1 - 0.0013 18.8 0.4 0.005 16.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EIM80648.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Cyt-b5 PF00173.23 EIM80650.1 - 5.5e-10 38.9 0.0 7.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BCL9 PF11502.3 EIM80650.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DLL_N PF12413.3 EIM80653.1 - 1.1 10.3 8.5 0.096 13.7 1.5 2.2 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal NrfD PF03916.9 EIM80653.1 - 2.5 7.4 17.0 2.3 7.5 9.1 2.0 1 1 0 2 2 2 0 Polysulphide reductase, NrfD F-box-like PF12937.2 EIM80657.1 - 1.5e-09 37.3 1.5 4e-09 36.0 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM80657.1 - 2.1e-06 27.2 0.3 7.1e-06 25.5 0.2 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EIM80657.1 - 0.021 14.5 0.0 0.12 12.1 0.0 2.3 1 0 0 1 1 1 0 Leucine rich repeat DPBB_1 PF03330.13 EIM80659.1 - 1e-08 35.0 0.0 3.3e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM80659.1 - 0.0017 18.0 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 Barwin family Gal_Lectin PF02140.13 EIM80659.1 - 0.0097 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Galactose binding lectin domain Fer4_21 PF14697.1 EIM80659.1 - 0.096 12.5 0.6 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain DnaJ-X PF14308.1 EIM80660.1 - 2.3e-51 174.0 1.3 2.3e-51 174.0 0.9 1.5 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIM80660.1 - 4.2e-28 96.8 2.3 1.2e-27 95.4 1.6 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2762 PF10960.3 EIM80660.1 - 0.069 12.8 0.4 0.2 11.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Abhydrolase_6 PF12697.2 EIM80661.1 - 3.4e-12 46.7 0.0 5e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80661.1 - 3e-06 27.0 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EIM80661.1 - 0.037 13.7 0.0 0.096 12.3 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EIM80661.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thaumatin PF00314.12 EIM80662.1 - 1.8e-62 210.6 7.8 2e-62 210.4 5.4 1.0 1 0 0 1 1 1 1 Thaumatin family F-box PF00646.28 EIM80663.1 - 0.015 14.9 0.2 0.048 13.3 0.1 1.9 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EIM80663.1 - 0.11 12.1 3.6 2.1 8.0 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM80663.1 - 0.86 9.4 4.0 4.2 7.1 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat Proteasome PF00227.21 EIM80664.1 - 6.3e-27 94.1 0.1 7.4e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1918 PF08940.6 EIM80665.1 - 0.021 14.1 0.0 0.95 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) JmjC PF02373.17 EIM80667.1 - 9.3e-39 132.2 0.1 2.3e-38 130.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EIM80667.1 - 7.9e-16 57.2 0.2 1.9e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EIM80667.1 - 3.4e-12 46.3 2.2 9.5e-12 44.9 1.5 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EIM80667.1 - 1.3e-09 38.0 7.6 3.9e-09 36.5 5.2 1.8 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 EIM80667.1 - 0.0015 18.1 2.2 0.0048 16.5 1.5 1.9 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 EIM80668.1 - 1.1e-40 139.4 0.0 1.6e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80668.1 - 3.8e-19 68.7 0.0 5.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM80668.1 - 1.5e-08 33.9 0.0 2.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.2 EIM80669.1 - 8.4e-07 28.6 0.0 2.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF1242 PF06842.7 EIM80670.1 - 9.1e-19 66.6 1.2 1.2e-18 66.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.8 EIM80670.1 - 0.28 11.2 1.1 0.36 10.8 0.1 1.6 2 0 0 2 2 2 0 LST-1 protein Alpha-amylase PF00128.19 EIM80671.1 - 4.1e-31 108.5 0.2 8.6e-31 107.4 0.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EIM80671.1 - 0.00011 20.1 0.2 0.16 9.7 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EIM80671.1 - 0.0034 17.2 0.2 0.0085 15.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_88 PF07470.8 EIM80672.1 - 7.8e-17 61.3 1.6 1.3e-16 60.5 1.1 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1905 PF08922.6 EIM80672.1 - 0.04 13.4 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) DUF515 PF04415.7 EIM80672.1 - 9.8 4.2 8.3 16 3.6 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pheromone PF08015.6 EIM80673.1 - 0.0033 18.2 1.3 0.0033 18.2 0.9 2.5 2 2 0 2 2 2 1 Fungal mating-type pheromone DUF294 PF03445.8 EIM80676.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Nop14 PF04147.7 EIM80677.1 - 0.017 13.0 5.3 0.018 12.9 3.7 1.1 1 0 0 1 1 1 0 Nop14-like family Fmp27 PF10344.4 EIM80677.1 - 0.073 10.7 3.1 0.093 10.4 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CDC45 PF02724.9 EIM80677.1 - 0.073 11.1 3.1 0.089 10.8 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Kei1 PF08552.6 EIM80677.1 - 0.12 12.0 0.5 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Trypan_PARP PF05887.6 EIM80677.1 - 0.29 10.9 4.7 0.51 10.1 3.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFMR PF07777.6 EIM80677.1 - 0.55 10.1 3.4 1.3 8.9 2.3 1.6 1 1 0 1 1 1 0 G-box binding protein MFMR NESP55 PF06390.7 EIM80677.1 - 2.7 7.3 14.8 6.3 6.1 10.2 1.6 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) BUD22 PF09073.5 EIM80677.1 - 3.1 6.7 15.0 5.6 5.9 10.4 1.3 1 0 0 1 1 1 0 BUD22 Trm112p PF03966.11 EIM80679.1 - 4.6e-20 71.7 0.0 5.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 EIM80679.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EIM80679.1 - 0.096 12.4 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.7 EIM80679.1 - 0.19 11.0 0.8 0.38 10.1 0.3 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EIM80679.1 - 0.31 10.5 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain PfkB PF00294.19 EIM80680.1 - 8.7e-07 28.3 0.0 0.068 12.2 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase p450 PF00067.17 EIM80681.1 - 3.2e-50 171.0 0.0 3.4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80682.1 - 1.7e-53 181.7 0.0 3.5e-53 180.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80683.1 - 6.1e-50 170.0 0.0 6.8e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.13 EIM80684.1 - 3e-08 33.4 17.4 5.6e-08 32.5 12.1 1.5 1 0 0 1 1 1 1 MYND finger zf-AN1 PF01428.11 EIM80684.1 - 0.043 13.6 5.0 0.063 13.1 3.2 1.5 1 1 0 1 1 1 0 AN1-like Zinc finger zf-HIT PF04438.11 EIM80684.1 - 0.18 11.5 12.5 1.1 8.9 8.7 2.2 1 1 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 EIM80684.1 - 0.27 11.1 7.6 0.53 10.1 5.3 1.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 EIM80684.1 - 2.9 7.2 8.1 11 5.3 5.6 2.0 1 1 0 1 1 1 0 Life-span regulatory factor NIF PF03031.13 EIM80686.1 - 1.1e-14 54.4 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AhpC-TSA PF00578.16 EIM80687.1 - 3e-38 130.2 0.0 4.6e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM80687.1 - 2.7e-13 49.6 0.0 3.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIM80687.1 - 5.9e-11 41.8 0.0 1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin RNase_PH PF01138.16 EIM80688.1 - 1.1e-19 71.0 0.0 1.7e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIM80688.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.2 EIM80689.1 - 0.00079 19.0 0.1 0.0023 17.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM80689.1 - 0.033 13.8 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 F-box domain SOG2 PF10428.4 EIM80689.1 - 9.8 4.6 13.7 16 3.9 9.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF262 PF03235.9 EIM80690.1 - 1.1e-17 64.7 1.4 3.5e-17 63.1 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 adh_short PF00106.20 EIM80691.1 - 3.3e-14 53.1 0.2 5.1e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM80691.1 - 4e-07 30.0 0.0 1e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM80691.1 - 3e-05 23.7 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM80691.1 - 0.046 13.1 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM80691.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 EIM80692.1 - 3.4e-22 79.1 0.0 4.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM80692.1 - 6.6e-10 39.1 0.0 8.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM80692.1 - 2.3e-08 33.9 0.0 3.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIM80692.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM80692.1 - 0.0024 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM80692.1 - 0.0033 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CTP_transf_2 PF01467.21 EIM80693.1 - 2e-27 96.1 0.0 2.6e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase RAI1 PF08652.6 EIM80695.1 - 2.8e-06 27.0 0.1 6.5e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease His_Phos_2 PF00328.17 EIM80696.1 - 2.8e-08 33.4 0.0 4.9e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TPR_16 PF13432.1 EIM80697.1 - 8.9e-13 48.5 2.2 1e-05 26.0 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SRP72 PF08492.7 EIM80697.1 - 2.3e-10 40.7 2.2 2.3e-10 40.7 1.5 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EIM80697.1 - 2.3e-09 37.4 8.7 9.4e-06 25.8 1.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM80697.1 - 1.2e-08 34.8 3.5 0.098 13.3 0.6 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EIM80697.1 - 3.8e-08 33.3 6.0 0.00031 20.8 1.5 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EIM80697.1 - 1.5e-06 27.6 3.2 0.7 9.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM80697.1 - 0.00016 21.2 7.1 0.031 13.9 0.1 3.1 1 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.1 EIM80697.1 - 0.00037 20.3 5.5 0.025 14.4 2.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM80697.1 - 0.0064 16.4 0.2 0.0064 16.4 0.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIM80697.1 - 0.0091 15.0 6.3 0.017 14.1 2.7 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM80697.1 - 0.026 14.9 5.7 2.6 8.6 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EIM80697.1 - 0.049 12.3 2.5 1.9 7.1 0.1 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 EIM80697.1 - 0.084 12.7 2.2 3 7.8 0.0 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EIM80697.1 - 0.089 13.0 1.6 23 5.2 1.0 2.7 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 EIM80697.1 - 0.15 12.3 2.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM80697.1 - 0.54 10.2 2.6 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.8 EIM80698.1 - 4.8e-13 48.8 8.0 4.8e-13 48.8 5.5 3.7 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region TEA PF01285.13 EIM80699.1 - 1.2e-14 54.3 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family Cellulase PF00150.13 EIM80701.1 - 0.00013 21.2 0.2 0.00021 20.6 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Parvo_coat_N PF08398.5 EIM80701.1 - 0.12 12.2 0.3 0.31 10.8 0.2 1.7 1 0 0 1 1 1 0 Parvovirus coat protein VP1 UBN2 PF14223.1 EIM80702.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Mucin PF01456.12 EIM80704.1 - 0.0091 15.7 4.1 0.098 12.4 0.3 2.1 2 0 0 2 2 2 2 Mucin-like glycoprotein C6 PF01681.12 EIM80704.1 - 0.014 15.4 0.5 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 C6 domain FGF-BP1 PF06473.7 EIM80704.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DRIM PF07539.7 EIM80705.1 - 2.1e-36 124.4 0.7 1.7e-35 121.4 0.0 3.0 4 0 0 4 4 4 1 Down-regulated in metastasis PRD PF00874.15 EIM80705.1 - 0.04 14.0 0.1 9.3 6.4 0.0 2.7 2 0 0 2 2 2 0 PRD domain HSP90 PF00183.13 EIM80705.1 - 2.4 6.4 5.2 4.3 5.6 0.3 2.3 2 0 0 2 2 2 0 Hsp90 protein CTK3 PF12243.3 EIM80706.1 - 5.7e-45 152.3 0.1 7.9e-45 151.9 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EIM80706.1 - 3.8e-15 55.6 13.4 2.4e-13 49.9 9.3 2.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF3554 PF12074.3 EIM80707.1 - 1.1e-41 143.4 9.4 1.6e-40 139.6 0.3 4.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EIM80707.1 - 7.7e-36 122.2 33.1 1.6e-06 28.2 0.1 14.1 6 3 4 13 13 13 10 HEAT repeats HEAT PF02985.17 EIM80707.1 - 6.5e-32 106.7 15.8 0.032 14.2 0.0 18.8 21 0 0 21 21 21 8 HEAT repeat HEAT_EZ PF13513.1 EIM80707.1 - 2.5e-31 107.3 31.2 2.1e-05 24.8 0.1 18.3 12 4 8 20 20 20 10 HEAT-like repeat CLASP_N PF12348.3 EIM80707.1 - 1.8e-16 60.2 0.0 7.7e-05 22.1 0.0 7.0 5 2 3 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIM80707.1 - 2.8e-06 27.6 0.0 1.8 9.0 0.0 6.2 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIM80707.1 - 7.2e-06 25.9 0.0 1.6 8.5 0.0 6.9 6 2 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EIM80707.1 - 0.039 13.8 0.4 64 3.3 0.0 5.2 4 1 1 5 5 5 0 Parkin co-regulated protein polyprenyl_synt PF00348.12 EIM80708.1 - 1e-49 168.7 0.0 5e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase FliL PF03748.9 EIM80708.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL zinc_ribbon_2 PF13240.1 EIM80709.1 - 0.69 9.4 6.1 1.6 8.3 1.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIM80709.1 - 0.74 9.1 3.9 5.8 6.2 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-MYND PF01753.13 EIM80713.1 - 3.9e-08 33.0 10.1 8e-08 32.0 7.0 1.5 1 0 0 1 1 1 1 MYND finger HNH_2 PF13391.1 EIM80721.1 - 0.032 14.0 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 HNH endonuclease HNH_2 PF13391.1 EIM80722.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 EIM80723.1 - 2.3e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Cyclase PF04199.8 EIM80724.1 - 1e-29 103.3 0.1 1.3e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_31 PF01055.21 EIM80725.1 - 3.6e-147 490.7 7.8 4.7e-147 490.3 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM80725.1 - 3.1e-18 65.3 0.1 8.2e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like HNH_2 PF13391.1 EIM80726.1 - 0.0011 18.6 0.1 0.003 17.3 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease APP_N PF02177.11 EIM80726.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding GLTSCR1 PF15249.1 EIM80726.1 - 0.13 12.3 0.3 2.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Glioma tumor suppressor candidate region HNH_2 PF13391.1 EIM80727.1 - 0.0016 18.1 0.1 0.0072 16.0 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease GATase_5 PF13507.1 EIM80728.1 - 3.2e-90 301.5 0.0 5.7e-90 300.7 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EIM80728.1 - 1.3e-43 148.5 3.2 1.3e-22 80.4 0.5 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIM80728.1 - 6.3e-23 80.8 0.2 2.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain HNH_2 PF13391.1 EIM80728.1 - 1e-05 25.2 0.2 2.1e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 EIM80729.1 - 0.0056 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease 3HCDH_N PF02737.13 EIM80730.1 - 3.8e-50 170.0 0.8 3.3e-49 166.9 0.5 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIM80730.1 - 3.3e-32 110.7 0.0 7.7e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIM80730.1 - 0.02 14.7 0.4 0.078 12.8 0.3 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EIM80730.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIM80731.1 - 7.7e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM80731.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Peptidase_S8 PF00082.17 EIM80732.1 - 5.2e-53 180.0 9.6 5.3e-53 179.9 6.0 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EIM80732.1 - 1.5e-14 54.2 0.0 3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DEAD PF00270.24 EIM80733.1 - 1.2e-18 67.1 0.0 2.5e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM80733.1 - 7.5e-09 35.6 0.0 5e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIM80733.1 - 4.1e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM80734.1 - 1.9e-44 151.0 0.3 3.4e-44 150.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM80734.1 - 4.6e-19 68.0 0.0 1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-MYND PF01753.13 EIM80734.1 - 4e-08 32.9 12.2 7.7e-08 32.0 8.4 1.5 1 0 0 1 1 1 1 MYND finger ResIII PF04851.10 EIM80734.1 - 6.2e-05 22.9 0.1 0.0001 22.1 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HNH_2 PF13391.1 EIM80735.1 - 0.0085 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 EIM80736.1 - 0.00077 19.1 0.3 0.0018 17.9 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease Sulfate_transp PF00916.15 EIM80739.1 - 1.6e-57 194.6 5.8 1.6e-57 194.6 4.0 2.2 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIM80739.1 - 3.3e-25 87.5 5.3 3.3e-25 87.5 3.7 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIM80739.1 - 5.7e-18 64.4 0.0 9.4e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIM80739.1 - 3.1e-05 23.9 0.0 9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 STAS domain DUF3649 PF12365.3 EIM80739.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) WD40 PF00400.27 EIM80740.1 - 0.0011 18.7 19.0 0.3 11.0 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ArsB PF02040.10 EIM80741.1 - 2.4e-15 56.4 18.9 9.5e-10 37.9 4.5 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein Pkinase PF00069.20 EIM80742.1 - 1.3e-62 211.3 0.0 1.5e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80742.1 - 1.2e-30 106.4 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1903 PF08991.5 EIM80743.1 - 1.7e-18 66.5 3.9 2e-18 66.3 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EIM80743.1 - 0.011 15.6 4.2 0.011 15.6 2.9 1.7 1 1 1 2 2 2 0 CHCH domain Pet191_N PF10203.4 EIM80743.1 - 0.11 12.5 4.0 0.15 12.1 2.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 EIM80743.1 - 0.15 11.4 4.2 0.21 11.0 2.9 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIM80743.1 - 1.4 8.6 8.4 0.35 10.6 1.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like SNF2_N PF00176.18 EIM80744.1 - 5.1e-71 238.9 0.4 7.7e-71 238.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM80744.1 - 1.2e-13 50.6 0.1 8.8e-13 47.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM80744.1 - 7.7e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIM80744.1 - 0.0051 15.6 0.0 1.7 7.3 0.0 2.9 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 DUF1970 PF09301.5 EIM80744.1 - 0.031 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Mito_carr PF00153.22 EIM80747.1 - 1.9e-66 219.8 1.8 3.5e-21 74.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Calpain_III PF01067.17 EIM80748.1 - 3e-24 85.3 0.0 1.2e-10 41.2 0.0 3.4 4 1 0 4 4 4 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EIM80748.1 - 1.2e-15 57.3 0.0 1.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EIM80748.1 - 1.2e-05 25.0 0.4 2e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DnaJ PF00226.26 EIM80749.1 - 4.4e-14 51.9 0.0 7.3e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.17 EIM80751.1 - 7e-51 173.1 0.0 8.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRRNT_2 PF08263.7 EIM80752.1 - 0.013 15.4 3.8 0.047 13.6 2.6 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 EIM80752.1 - 0.067 12.9 6.1 0.086 12.6 2.6 2.3 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EIM80752.1 - 0.093 12.3 6.0 0.55 9.9 0.7 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Pantoate_transf PF02548.10 EIM80754.1 - 1.4e-94 316.1 0.1 1.5e-87 293.0 0.0 2.0 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EIM80754.1 - 0.0057 15.8 0.0 0.025 13.7 0.0 2.0 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Mur_ligase PF01225.20 EIM80754.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Init_tRNA_PT PF04179.7 EIM80755.1 - 2.8e-117 392.3 0.0 4.9e-117 391.5 0.0 1.3 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase ER_lumen_recept PF00810.13 EIM80756.1 - 6.3e-60 201.9 5.2 8.9e-60 201.4 3.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EIM80756.1 - 5.7e-05 22.5 5.1 0.4 10.2 0.0 4.0 2 1 2 4 4 4 3 PQ loop repeat Lectin_leg-like PF03388.8 EIM80757.1 - 3e-68 229.3 0.4 4e-68 228.9 0.3 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EIM80757.1 - 0.00088 18.7 0.0 0.003 16.9 0.0 1.9 1 1 0 1 1 1 1 Legume lectin domain Dimer_Tnp_hAT PF05699.9 EIM80760.1 - 2.8e-06 26.8 0.3 0.033 13.8 0.0 3.0 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region FSH1 PF03959.8 EIM80761.1 - 6.5e-56 189.1 0.0 7.9e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIM80761.1 - 2.2e-07 31.0 0.0 0.012 15.4 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80761.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIM80761.1 - 0.00019 20.9 0.1 0.037 13.4 0.1 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 EIM80761.1 - 0.031 13.5 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family HEAT PF02985.17 EIM80762.1 - 4.1e-26 88.6 13.5 0.00016 21.4 0.0 10.5 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 EIM80762.1 - 5.6e-24 83.9 17.4 4.3e-13 49.3 0.0 10.5 10 2 1 11 11 11 2 HEAT-like repeat HEAT_2 PF13646.1 EIM80762.1 - 6e-21 74.5 0.3 8.1e-06 26.0 0.0 7.1 4 4 4 8 8 8 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EIM80762.1 - 3.4e-08 33.7 0.0 0.098 13.0 0.1 4.8 4 2 1 5 5 4 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIM80762.1 - 3.5e-08 33.4 0.7 0.11 12.3 0.1 6.0 5 3 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EIM80762.1 - 1.1e-06 28.5 0.1 0.31 11.0 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 EIM80762.1 - 4.4e-05 23.0 0.2 0.037 13.7 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Arm PF00514.18 EIM80762.1 - 0.00025 20.7 0.3 4.4 7.2 0.0 5.4 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EIM80762.1 - 0.00045 19.6 0.0 1 8.6 0.0 3.8 4 0 0 4 4 4 1 CLASP N terminal Adaptin_N PF01602.15 EIM80762.1 - 0.00052 18.4 0.6 0.12 10.7 0.1 3.5 4 0 0 4 4 4 1 Adaptin N terminal region Cnd3 PF12719.2 EIM80762.1 - 0.068 12.1 0.3 0.28 10.1 0.0 2.1 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain UNC45-central PF11701.3 EIM80762.1 - 0.078 12.6 0.1 0.33 10.6 0.0 2.2 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central UME PF08064.8 EIM80762.1 - 0.097 12.6 0.2 5.2 7.0 0.0 3.3 4 0 0 4 4 2 0 UME (NUC010) domain MMS19_C PF12460.3 EIM80762.1 - 0.59 8.8 3.2 25 3.4 0.0 3.5 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal p450 PF00067.17 EIM80763.1 - 1.8e-52 178.4 0.1 2e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kri1_C PF12936.2 EIM80764.1 - 7e-25 86.8 1.1 7e-25 86.8 0.7 5.6 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EIM80764.1 - 8.1e-20 70.9 9.3 8.1e-20 70.9 6.4 7.6 6 2 1 7 7 7 1 KRI1-like family Dynamin_N PF00350.18 EIM80765.1 - 4e-13 49.5 0.0 5.9e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM80765.1 - 9.5e-06 24.5 0.0 1.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EIM80765.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_M PF01031.15 EIM80766.1 - 3e-06 26.2 0.0 3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EIM80767.1 - 1.4e-08 34.4 0.3 2.5e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.15 EIM80768.1 - 7.8e-28 97.0 0.0 1.3e-15 56.9 0.0 2.6 2 1 1 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 EIM80768.1 - 8.9e-28 97.2 0.0 2.8e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIM80768.1 - 4.1e-06 26.7 0.0 2.7e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Orthopox_F14 PF06076.7 EIM80768.1 - 0.0087 16.0 0.3 0.26 11.3 0.1 2.5 2 0 0 2 2 2 1 Orthopoxvirus F14 protein Miro PF08477.8 EIM80768.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EIM80768.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PBP1_TM PF14812.1 EIM80771.1 - 0.0067 16.7 3.6 0.0067 16.7 2.5 1.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2956 PF11169.3 EIM80771.1 - 0.091 12.7 0.7 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) YqzE PF14038.1 EIM80771.1 - 0.1 12.3 0.7 0.19 11.4 0.5 1.4 1 0 0 1 1 1 0 YqzE-like protein Nucleo_P87 PF07267.6 EIM80771.1 - 0.78 8.3 8.5 1.1 7.8 5.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EIM80771.1 - 3.4 5.5 7.4 3.8 5.4 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tfb4 PF03850.9 EIM80772.1 - 0.089 12.0 0.4 0.12 11.5 0.3 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 adh_short_C2 PF13561.1 EIM80773.1 - 4.8e-19 69.0 0.0 5.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM80773.1 - 1.7e-18 67.0 0.1 2.2e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM80773.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Dynamin_N PF00350.18 EIM80775.1 - 6.1e-28 97.7 0.0 1.2e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM80775.1 - 6.2e-22 77.7 0.0 5.1e-15 55.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin central region GED PF02212.13 EIM80775.1 - 3.2e-12 46.1 0.7 1.9e-11 43.6 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM80775.1 - 1.7e-05 24.7 0.0 7.9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EIM80775.1 - 0.019 14.4 0.1 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EIM80775.1 - 0.037 14.5 0.1 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 EIM80775.1 - 0.04 13.8 0.9 0.1 12.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EIM80775.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Syntaxin_2 PF14523.1 EIM80775.1 - 0.083 12.9 0.1 0.083 12.9 0.1 2.2 3 0 0 3 3 3 0 Syntaxin-like protein AAA_23 PF13476.1 EIM80775.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ceramidase_alk PF04734.8 EIM80776.1 - 2.7e-252 838.5 0.6 3.1e-252 838.3 0.4 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF2828 PF11443.3 EIM80777.1 - 2.6e-153 511.0 0.0 5.3e-153 510.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) zf-MYND PF01753.13 EIM80778.1 - 0.0011 18.7 10.4 0.0022 17.8 7.2 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EIM80778.1 - 3.8 7.2 8.3 7 6.3 5.8 1.4 1 0 0 1 1 1 0 HIT zinc finger MULE PF10551.4 EIM80782.1 - 1.8e-08 34.4 0.0 5.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM80782.1 - 0.00013 21.3 0.5 0.00035 19.9 0.4 1.7 1 0 0 1 1 1 1 SWIM zinc finger SET PF00856.23 EIM80783.1 - 0.00097 19.4 1.6 0.0021 18.3 1.1 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EIM80784.1 - 1.5e-06 27.9 12.8 2.8e-06 27.0 8.8 1.5 1 0 0 1 1 1 1 MYND finger Lipase_GDSL PF00657.17 EIM80785.1 - 1.5e-09 38.0 6.9 2.9e-09 37.1 4.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NAD_binding_5 PF07994.7 EIM80786.1 - 8.5e-106 353.7 0.0 1e-105 353.4 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EIM80786.1 - 4.8e-44 148.7 0.1 8.7e-44 147.9 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase p450 PF00067.17 EIM80787.1 - 7.3e-64 215.9 0.0 8.7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80788.1 - 5.1e-73 246.1 0.0 5.8e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sen15 PF09631.5 EIM80789.1 - 2.7e-20 72.4 0.0 3.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein NIF PF03031.13 EIM80790.1 - 1.2e-35 122.5 0.0 1.6e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EIM80790.1 - 0.038 14.1 0.0 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2076 PF09849.4 EIM80790.1 - 0.69 9.9 10.0 6.3 6.7 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ATP-synt_E PF05680.7 EIM80790.1 - 2.5 8.1 5.8 2.4 8.1 1.5 2.1 2 0 0 2 2 2 0 ATP synthase E chain DUF2723 PF11028.3 EIM80791.1 - 0.17 11.3 12.4 0.27 10.7 5.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) F-box-like PF12937.2 EIM80792.1 - 9.8e-05 22.0 0.7 0.00022 20.9 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM80792.1 - 0.0064 16.1 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_31 PF01055.21 EIM80793.1 - 2.8e-50 171.4 4.4 3.9e-50 170.9 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM80793.1 - 0.005 16.6 0.4 0.024 14.4 0.3 2.3 1 1 0 1 1 1 1 Galactose mutarotase-like Cpn60_TCP1 PF00118.19 EIM80796.1 - 1.8e-131 439.1 0.3 2e-131 438.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EIM80796.1 - 0.021 14.8 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor F-box-like PF12937.2 EIM80797.1 - 0.0015 18.2 0.7 0.0037 16.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like Trigger_N PF05697.8 EIM80798.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) F-box-like PF12937.2 EIM80801.1 - 0.011 15.4 0.5 0.011 15.4 0.4 2.4 3 0 0 3 3 3 0 F-box-like LRR_4 PF12799.2 EIM80801.1 - 0.016 14.8 2.9 0.26 10.9 0.1 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) KR PF08659.5 EIM80802.1 - 3.6e-05 23.5 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM80802.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF2339 PF10101.4 EIM80802.1 - 0.16 10.2 1.8 0.25 9.6 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Glyco_hydro_28 PF00295.12 EIM80803.1 - 6.5e-56 189.6 21.4 8.4e-56 189.2 14.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM80803.1 - 2.2e-08 33.9 31.1 2.9e-08 33.6 11.0 3.5 2 2 0 3 3 3 1 Right handed beta helix region DUF1565 PF07602.6 EIM80803.1 - 1e-05 24.8 2.5 1e-05 24.8 1.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1565) TOBE_2 PF08402.5 EIM80803.1 - 0.041 13.8 0.2 3.7 7.5 0.0 3.4 3 0 0 3 3 3 0 TOBE domain ATP-grasp PF02222.17 EIM80804.1 - 0.0096 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain TMEM154 PF15102.1 EIM80805.1 - 0.00036 20.2 1.6 0.00042 20.0 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.11 EIM80805.1 - 0.0069 14.6 0.1 0.012 13.8 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EIM80805.1 - 0.0069 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) gpUL132 PF11359.3 EIM80805.1 - 0.014 14.7 0.1 0.014 14.7 0.1 3.1 4 0 0 4 4 4 0 Glycoprotein UL132 Protocadherin PF08374.6 EIM80805.1 - 0.03 13.9 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 EIM80805.1 - 0.036 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 EIM80805.1 - 0.05 13.0 4.8 0.12 11.7 3.3 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Mito_carr PF00153.22 EIM80806.1 - 7.4e-61 201.8 4.9 3.8e-22 77.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4470 PF14737.1 EIM80807.1 - 2.8e-19 68.6 0.1 4.7e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM80807.1 - 7.1e-05 22.5 8.1 0.00013 21.7 5.6 1.4 1 0 0 1 1 1 1 MYND finger CHAT PF12770.2 EIM80808.1 - 3.3e-36 124.9 0.0 6e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain RhoGAP PF00620.22 EIM80809.1 - 4.2e-41 140.0 0.0 1e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 EIM80809.1 - 1.9e-11 44.0 0.0 2.8e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 RasGEF domain PH PF00169.24 EIM80809.1 - 3.1e-07 30.5 0.0 0.023 14.8 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 EIM80809.1 - 1.1e-06 28.7 0.0 1.3e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain RasGEF_N PF00618.15 EIM80809.1 - 0.00012 22.1 0.1 0.0012 18.8 0.0 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif KAP PF05804.7 EIM80809.1 - 0.49 8.2 0.1 0.75 7.6 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) p450 PF00067.17 EIM80810.1 - 4.6e-64 216.6 0.0 5.6e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80811.1 - 1.4e-09 36.9 0.0 1.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2H-phosphodiest PF08975.5 EIM80811.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Peptidase_C12 PF01088.16 EIM80812.1 - 1.6e-46 158.2 0.0 2e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 F-box-like PF12937.2 EIM80813.1 - 0.00018 21.1 0.3 0.0017 18.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like 2OG-FeII_Oxy_3 PF13640.1 EIM80814.1 - 0.0018 18.7 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM80814.1 - 0.014 15.6 0.1 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Bromodomain PF00439.20 EIM80816.1 - 2.5e-22 78.5 0.9 6.4e-22 77.2 0.6 1.7 1 1 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EIM80816.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 EIM80818.1 - 3.9e-29 99.4 19.8 2.9e-07 30.1 0.0 7.1 6 2 1 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIM80818.1 - 1.8e-05 24.5 0.2 0.0044 16.7 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A GHMP_kinases_N PF00288.21 EIM80818.1 - 0.074 13.1 1.6 0.33 11.0 1.1 2.1 1 0 0 1 1 1 0 GHMP kinases N terminal domain TPIP1 PF15338.1 EIM80819.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 2OG-FeII_Oxy_3 PF13640.1 EIM80820.1 - 0.0001 22.7 0.0 0.00028 21.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM80820.1 - 0.0025 18.0 0.1 0.0063 16.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_1 PF00036.27 EIM80821.1 - 2.2e-23 79.6 1.0 1.7e-06 26.8 0.1 4.8 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EIM80821.1 - 5.5e-22 75.6 0.9 2.6e-07 29.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EIM80821.1 - 2.9e-19 68.9 1.1 6.5e-10 39.0 0.1 2.6 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIM80821.1 - 2.7e-17 61.2 1.0 0.00041 19.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIM80821.1 - 6.4e-12 44.9 6.2 5e-07 29.2 0.0 4.5 3 3 2 5 5 5 2 EF-hand domain pair Toprim_2 PF13155.1 EIM80821.1 - 0.0042 17.3 0.1 4.7 7.5 0.0 2.8 1 1 2 3 3 3 2 Toprim-like PEP_mutase PF13714.1 EIM80822.1 - 4.7e-44 150.3 0.4 5.8e-44 150.0 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EIM80822.1 - 1.3e-20 73.1 0.5 1.8e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PARP PF00644.15 EIM80823.1 - 6.3e-13 48.6 1.8 1.1e-09 38.0 0.0 2.8 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Ecl1 PF12855.2 EIM80823.1 - 3.5 6.9 9.7 0.3 10.4 0.3 2.8 2 1 0 2 2 2 0 Life-span regulatory factor F-box PF00646.28 EIM80824.1 - 0.00017 21.1 0.5 0.00047 19.7 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM80824.1 - 0.00025 20.6 1.1 0.00072 19.2 0.7 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM80824.1 - 1.7 8.3 4.6 3.6 7.3 0.0 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) ABC_tran PF00005.22 EIM80826.1 - 1.4e-30 106.3 0.0 9.7e-16 58.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM80826.1 - 6.9e-08 32.7 0.8 0.00048 20.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EIM80826.1 - 1.1e-05 25.2 0.3 0.054 13.4 0.0 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EIM80826.1 - 0.0088 15.5 0.0 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SPC25 PF06703.6 EIM80826.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SMC_N PF02463.14 EIM80826.1 - 0.064 12.4 0.0 0.19 10.9 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Phage_GP20 PF06810.6 EIM80826.1 - 0.082 12.3 0.0 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_22 PF13401.1 EIM80826.1 - 0.082 13.0 0.0 4.5 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF3584 PF12128.3 EIM80826.1 - 0.092 10.0 0.1 0.13 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EIM80826.1 - 0.13 10.6 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain V-SNARE_C PF12352.3 EIM80830.1 - 1.7e-16 60.0 0.3 1.7e-16 60.0 0.2 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIM80830.1 - 2.8e-08 33.3 0.6 5.4e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 Sec20 Wbp11 PF09429.5 EIM80830.1 - 0.003 17.4 2.7 0.26 11.3 1.8 2.4 2 0 0 2 2 2 1 WW domain binding protein 11 Fmp27_WPPW PF10359.4 EIM80830.1 - 0.038 12.4 2.2 0.061 11.7 1.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Scaffolding_pro PF11418.3 EIM80830.1 - 0.064 13.5 0.6 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein Cortex-I_coil PF09304.5 EIM80830.1 - 0.22 11.5 4.7 0.16 12.0 0.9 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.15 EIM80830.1 - 0.3 10.8 5.6 0.92 9.2 2.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4613 PF15390.1 EIM80830.1 - 0.53 8.4 3.9 0.63 8.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3513 PF12026.3 EIM80830.1 - 0.8 9.2 5.2 1.7 8.1 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3513) ADIP PF11559.3 EIM80830.1 - 2.6 7.9 9.5 0.21 11.4 3.0 1.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mcm10 PF09332.6 EIM80830.1 - 3.7 6.8 9.8 3.3 6.9 5.0 1.8 1 1 1 2 2 2 0 Mcm10 replication factor Plasmid_RAQPRD PF09686.5 EIM80830.1 - 6.3 6.9 9.2 1.4 9.0 1.9 2.9 2 1 2 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Peptidase_M28 PF04389.12 EIM80831.1 - 3.8e-28 98.4 0.2 5.9e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EIM80831.1 - 0.0003 19.6 0.0 0.00077 18.3 0.0 1.6 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase DUF1469 PF07332.6 EIM80831.1 - 0.026 14.2 0.1 0.026 14.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) RRM_6 PF14259.1 EIM80833.1 - 1.7e-34 117.6 0.3 1.1e-09 38.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM80833.1 - 6.8e-30 102.5 1.7 4.1e-09 35.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM80833.1 - 6.5e-17 61.1 0.0 0.00067 19.4 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM80833.1 - 0.00011 21.9 2.9 0.032 14.0 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif FCH PF00611.18 EIM80835.1 - 2.6e-19 69.1 1.5 6.3e-19 67.9 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EIM80835.1 - 2.4e-11 42.8 0.0 4.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM80835.1 - 1.5e-09 37.2 0.0 3.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM80835.1 - 3.7e-07 29.5 0.0 1.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.23 EIM80836.1 - 8e-08 31.9 2.6 1.3e-07 31.2 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Bac_rhodopsin PF01036.13 EIM80840.1 - 6.6e-39 133.5 18.8 7.8e-39 133.2 13.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PAPA-1 PF04795.7 EIM80841.1 - 2e-12 47.5 10.6 2e-12 47.5 7.4 2.5 2 1 0 2 2 2 1 PAPA-1-like conserved region F-box-like PF12937.2 EIM80845.1 - 2.3e-09 36.8 0.4 6.4e-09 35.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like zf-C2HC_2 PF13913.1 EIM80845.1 - 0.0038 16.8 0.1 0.0076 15.8 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Ank_5 PF13857.1 EIM80846.1 - 1e-12 47.8 0.2 3.8e-05 23.7 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM80846.1 - 7.6e-12 45.4 0.1 8.8e-06 25.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM80846.1 - 9.8e-11 40.9 0.8 4.4e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EIM80846.1 - 1.9e-10 39.9 0.2 1.1e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIM80846.1 - 4.1e-10 39.9 0.0 3.5e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.7 EIM80848.1 - 7.9e-72 241.8 29.3 1.6e-71 240.8 20.3 1.4 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EIM80848.1 - 0.026 12.5 19.9 0.04 11.9 13.8 1.3 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EIM80848.1 - 0.89 9.0 22.6 1.2 8.6 15.6 1.2 1 0 0 1 1 1 0 PPP4R2 TATR PF03430.8 EIM80848.1 - 6.9 5.1 12.7 12 4.3 8.8 1.5 1 1 0 1 1 1 0 Trans-activating transcriptional regulator F-box-like PF12937.2 EIM80849.1 - 2.1e-09 36.9 2.8 7.6e-09 35.1 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM80849.1 - 0.0027 17.2 2.4 0.0056 16.3 0.3 2.5 2 1 0 2 2 2 1 F-box domain Cupin_2 PF07883.6 EIM80850.1 - 1.2e-07 31.0 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EIM80850.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Imm45 PF15603.1 EIM80850.1 - 0.052 13.6 0.2 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 45 Acetyltransf_1 PF00583.19 EIM80851.1 - 0.00053 19.9 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM80851.1 - 0.00071 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM80851.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PseudoU_synth_2 PF00849.17 EIM80852.1 - 9.7e-28 97.0 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ABC_tran PF00005.22 EIM80853.1 - 1.4e-46 158.1 0.1 1.1e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EIM80853.1 - 8.2e-43 146.0 34.8 5.8e-30 104.0 9.7 3.4 3 1 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 EIM80853.1 - 1.4e-14 54.7 3.2 8.1e-07 29.2 0.4 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIM80853.1 - 5.7e-10 38.8 0.9 7.9e-05 21.9 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM80853.1 - 9.1e-08 31.7 0.5 0.004 16.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EIM80853.1 - 1e-07 31.2 1.9 0.0026 16.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EIM80853.1 - 2.2e-07 30.3 0.5 0.014 14.4 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_16 PF13191.1 EIM80853.1 - 7.9e-07 29.2 0.2 0.0039 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM80853.1 - 1e-06 28.1 3.0 0.0079 15.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIM80853.1 - 2.2e-06 28.1 0.3 0.0094 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIM80853.1 - 1.1e-05 26.1 0.0 0.19 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM80853.1 - 0.00012 22.1 0.6 0.27 11.3 0.0 3.1 3 2 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EIM80853.1 - 0.00013 22.2 0.3 0.19 12.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain PDR_CDR PF06422.7 EIM80853.1 - 0.00022 20.8 0.1 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 1 CDR ABC transporter SbcCD_C PF13558.1 EIM80853.1 - 0.00029 20.6 0.1 1.1 9.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIM80853.1 - 0.00043 19.9 0.0 0.028 14.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EIM80853.1 - 0.00058 19.3 3.7 0.2 11.0 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain RNA_helicase PF00910.17 EIM80853.1 - 0.00066 19.8 0.1 1 9.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EIM80853.1 - 0.00067 19.6 0.3 0.063 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM80853.1 - 0.00071 19.2 0.1 0.25 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIM80853.1 - 0.0014 18.2 0.1 1.8 8.2 0.0 3.0 3 0 0 3 3 3 1 NACHT domain KAP_NTPase PF07693.9 EIM80853.1 - 0.0028 16.7 0.0 0.93 8.4 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain AAA_5 PF07728.9 EIM80853.1 - 0.0029 17.3 0.3 3.4 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EIM80853.1 - 0.0045 16.9 0.4 1.8 8.5 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.2 EIM80853.1 - 0.0055 15.7 26.7 0.023 13.7 8.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ATP_bind_1 PF03029.12 EIM80853.1 - 0.007 15.9 0.4 1.5 8.3 0.1 2.7 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EIM80853.1 - 0.021 14.5 0.1 3.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIM80853.1 - 0.021 13.7 4.0 0.61 8.9 0.5 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EIM80853.1 - 0.023 14.4 0.2 1.8 8.2 0.0 3.4 4 0 0 4 4 4 0 NTPase Arch_ATPase PF01637.13 EIM80853.1 - 0.033 13.8 0.2 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EIM80853.1 - 0.039 13.0 0.1 9.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EIM80853.1 - 0.096 12.5 0.1 10 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIM80853.1 - 0.099 12.0 2.6 1.5 8.2 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EIM80853.1 - 0.11 12.9 0.1 29 5.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 EIM80853.1 - 0.12 11.8 2.4 5.1 6.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EIM80853.1 - 1.2 8.3 3.7 1.4 8.1 0.2 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein zf-MYND PF01753.13 EIM80855.1 - 0.00023 20.9 16.8 0.057 13.3 2.2 2.7 2 0 0 2 2 2 2 MYND finger DUF605 PF04652.11 EIM80856.1 - 0.02 14.3 6.7 0.029 13.7 4.6 1.2 1 0 0 1 1 1 0 Vta1 like Aminotran_5 PF00266.14 EIM80857.1 - 4.1e-21 75.1 0.0 3.4e-20 72.1 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V Uso1_p115_head PF04869.9 EIM80858.1 - 5.4e-37 127.2 0.0 4e-36 124.3 0.0 2.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EIM80858.1 - 8.1e-09 35.5 20.9 8.1e-09 35.5 14.5 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.9 EIM80858.1 - 0.11 12.4 7.3 0.21 11.4 5.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EIM80858.1 - 0.49 9.9 11.6 1.2 8.7 8.1 1.6 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EIM80858.1 - 3.5 6.1 11.7 5.5 5.5 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 EIM80858.1 - 6.6 7.1 11.3 0.41 11.0 1.1 3.0 1 1 2 3 3 3 0 SlyX DUF4407 PF14362.1 EIM80858.1 - 8.8 5.1 10.5 13 4.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) E1-E2_ATPase PF00122.15 EIM80859.1 - 8.4e-74 247.4 0.3 1.8e-73 246.3 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIM80859.1 - 2.9e-36 124.7 1.0 2.9e-36 124.7 0.7 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIM80859.1 - 4.5e-28 99.1 0.0 2.1e-27 96.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM80859.1 - 5e-15 56.1 0.0 2.5e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM80859.1 - 2.8e-12 46.4 0.0 8e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIM80859.1 - 7.7e-10 38.0 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM80859.1 - 3.1e-05 23.6 0.7 0.00069 19.2 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EIM80859.1 - 0.0057 16.2 0.0 0.0057 16.2 0.0 2.2 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC p450 PF00067.17 EIM80862.1 - 1.3e-71 241.5 0.0 4e-71 239.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 RNA_polI_A34 PF08208.6 EIM80864.1 - 0.087 12.4 17.3 0.15 11.7 12.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rab_eff_C PF04698.7 EIM80864.1 - 0.92 7.5 7.5 1.2 7.1 5.2 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus G-alpha PF00503.15 EIM80864.1 - 1.2 7.7 10.5 1.4 7.4 7.3 1.2 1 1 0 1 1 1 0 G-protein alpha subunit Rib_recp_KP_reg PF05104.7 EIM80864.1 - 1.8 9.0 15.6 3.3 8.2 10.8 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region U79_P34 PF03064.11 EIM80864.1 - 5.1 6.5 14.7 8.4 5.8 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Chitin_synth_2 PF03142.10 EIM80866.1 - 6.8e-15 54.4 0.6 5.2e-13 48.2 0.0 2.8 3 0 0 3 3 3 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIM80866.1 - 9.5e-14 51.7 0.2 1.6e-08 34.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIM80866.1 - 1.8e-06 27.7 19.2 5.5e-06 26.2 10.9 3.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIM80866.1 - 2.4e-06 27.3 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM80866.1 - 4.7e-05 22.7 0.1 8.8e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF3778 PF12620.3 EIM80866.1 - 0.17 11.4 0.1 0.17 11.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) Metallophos PF00149.23 EIM80868.1 - 3.8e-34 117.8 0.0 2.9e-33 114.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.2 EIM80869.1 - 1.1e-07 32.0 0.7 3.5e-07 30.3 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80869.1 - 3e-07 30.3 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIM80869.1 - 6.6e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 EIM80869.1 - 0.00059 19.2 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EIM80869.1 - 0.0012 19.0 1.4 0.0018 18.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 EIM80869.1 - 0.0053 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EIM80869.1 - 0.08 12.5 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIM80869.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Borrelia_P83 PF05262.6 EIM80869.1 - 1.2 7.2 13.9 2 6.5 9.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein GAGA_bind PF06217.7 EIM80869.1 - 2.8 7.8 11.6 4.9 7.0 8.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 EIM80869.1 - 6.9 4.2 8.5 9.7 3.7 5.9 1.2 1 0 0 1 1 1 0 Ycf1 Abhydrolase_6 PF12697.2 EIM80870.1 - 1.1e-21 77.8 0.0 1.3e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM80870.1 - 6.9e-09 35.5 0.0 3.5e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM80870.1 - 3.3e-08 33.3 0.2 2.7e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIM80870.1 - 0.053 13.7 0.9 2.7 8.1 0.2 2.4 3 0 0 3 3 3 0 Thioesterase domain Acetyltransf_3 PF13302.1 EIM80871.1 - 2.6e-17 63.3 0.1 3.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM80871.1 - 2e-12 46.9 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIM80871.1 - 4.5e-11 42.9 0.0 5.3e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM80871.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM80871.1 - 3.2e-05 23.8 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM80871.1 - 3.5e-05 23.4 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIM80871.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3817 PF12823.2 EIM80872.1 - 2.6 8.5 10.2 6.6 7.2 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3817) Phyto-Amp PF15438.1 EIM80873.1 - 0.0095 15.5 0.3 0.012 15.2 0.2 1.1 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma DUF3328 PF11807.3 EIM80874.1 - 1.1e-23 84.0 0.3 1.4e-23 83.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_6 PF12697.2 EIM80875.1 - 9.6e-21 74.6 0.0 1.3e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM80875.1 - 1.9e-10 40.7 0.0 3.4e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM80875.1 - 1.2e-07 31.6 0.0 3.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIM80875.1 - 0.14 11.5 0.0 0.72 9.2 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pro-kuma_activ PF09286.6 EIM80876.1 - 3.5e-38 130.8 0.0 5.8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM80876.1 - 0.0049 16.0 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Subtilase family DUF3670 PF12419.3 EIM80876.1 - 0.17 11.3 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 SNF2 Helicase protein IKI3 PF04762.7 EIM80878.1 - 7.5e-223 742.1 0.0 9.1e-168 559.9 0.0 2.6 2 1 1 3 3 3 2 IKI3 family Clathrin PF00637.15 EIM80878.1 - 0.039 13.5 3.4 3.6 7.1 0.0 3.5 2 1 2 4 4 4 0 Region in Clathrin and VPS DUF2361 PF10153.4 EIM80879.1 - 5.4e-31 107.1 8.8 5.4e-31 107.1 6.1 2.4 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2361) CCDC-167 PF15188.1 EIM80879.1 - 6.1 6.8 10.4 9.2 6.2 0.1 3.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Sigma70_r3 PF04539.11 EIM80880.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 Tricho_coat PF05892.6 EIM80882.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein DUF2463 PF09591.5 EIM80882.1 - 0.73 9.3 11.2 2.4 7.6 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2463) FAD_binding_4 PF01565.18 EIM80884.1 - 2e-12 46.7 1.9 4.1e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 EIM80884.1 - 1.3e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EIM80884.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.9 EIM80884.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase SprT-like PF10263.4 EIM80885.1 - 2.9e-40 137.4 0.0 4.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EIM80885.1 - 0.043 13.7 0.3 0.094 12.6 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Aldo_ket_red PF00248.16 EIM80886.1 - 5.7e-56 189.4 0.0 6.8e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ureide_permease PF07168.6 EIM80887.1 - 0.1 11.2 1.6 0.12 11.0 1.1 1.1 1 0 0 1 1 1 0 Ureide permease HAD_2 PF13419.1 EIM80888.1 - 7.9e-29 101.1 0.1 1.3e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM80888.1 - 0.002 17.7 0.0 0.0048 16.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3597 PF12200.3 EIM80888.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) RhoGEF PF00621.15 EIM80889.1 - 2.4e-28 99.2 0.0 2.9e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 RhoGEF domain DUF3246 PF11596.3 EIM80890.1 - 3.6 6.7 8.0 6.9 5.8 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) LRR_8 PF13855.1 EIM80892.1 - 0.047 13.4 1.3 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EIM80892.1 - 0.29 10.8 2.2 26 4.5 0.1 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Lactonase PF10282.4 EIM80893.1 - 1.2e-42 146.2 0.0 1.5e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CoA_transf_3 PF02515.12 EIM80894.1 - 6e-50 169.1 0.0 8.8e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III UPF0242 PF06785.6 EIM80895.1 - 0.0097 14.6 10.0 0.014 14.0 6.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) Phlebovirus_NSM PF07246.6 EIM80895.1 - 0.022 13.8 5.3 0.039 13.1 3.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GAS PF13851.1 EIM80895.1 - 0.072 12.2 12.6 0.3 10.2 8.7 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIM80895.1 - 0.28 10.1 11.3 0.56 9.1 7.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EIM80895.1 - 0.58 7.9 6.6 0.86 7.3 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 EIM80895.1 - 1.2 7.5 14.6 0.065 11.7 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HALZ PF02183.13 EIM80895.1 - 1.7 8.4 8.9 4.9 6.9 2.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mnd1 PF03962.10 EIM80895.1 - 1.7 8.2 9.7 4.1 7.0 6.7 1.7 1 0 0 1 1 1 0 Mnd1 family HAUS6_N PF14661.1 EIM80895.1 - 6.1 6.1 9.7 11 5.2 6.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF904 PF06005.7 EIM80895.1 - 9.5 6.5 15.4 3.4e+02 1.6 10.7 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) RNA_pol_A_bac PF01000.21 EIM80896.1 - 3.4e-22 78.6 0.0 6.3e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIM80896.1 - 1e-16 59.7 0.0 1.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M20 PF01546.23 EIM80897.1 - 5.6e-14 52.0 0.2 7.7e-14 51.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM80897.1 - 0.00021 20.9 0.0 0.00063 19.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM80897.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 F-box PF00646.28 EIM80899.1 - 0.028 14.0 0.3 0.059 13.0 0.1 1.7 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIM80899.1 - 0.032 13.9 1.0 0.032 13.9 0.7 2.4 2 0 0 2 2 2 0 F-box-like COG4 PF08318.7 EIM80900.1 - 0.04 12.6 3.5 0.025 13.3 0.8 1.8 2 0 0 2 2 2 0 COG4 transport protein DUF4615 PF15393.1 EIM80900.1 - 0.84 9.8 6.2 2.9 8.1 4.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) GST_N_3 PF13417.1 EIM80901.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DisA_N PF02457.11 EIM80901.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DUF2353 PF09789.4 EIM80902.1 - 0.0073 15.6 4.8 0.013 14.7 3.3 1.6 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.7 EIM80902.1 - 0.83 9.4 11.3 0.13 11.9 3.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIM80902.1 - 3 7.6 5.1 3.1 7.5 0.9 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 EIM80902.1 - 3.9 7.8 8.6 0.94 9.8 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Striatin PF08232.7 EIM80902.1 - 4.7 7.5 11.9 40 4.5 8.3 2.2 1 1 0 1 1 1 0 Striatin family FlxA PF14282.1 EIM80902.1 - 8.7 6.3 10.2 0.35 10.8 0.6 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF3584 PF12128.3 EIM80905.1 - 0.032 11.5 9.0 0.042 11.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 EIM80905.1 - 0.059 12.5 10.2 0.1 11.8 7.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC PF05010.9 EIM80905.1 - 0.81 9.4 9.5 1.5 8.4 6.6 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF972 PF06156.8 EIM80905.1 - 0.96 9.8 8.2 0.5 10.7 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EIM80905.1 - 1.3 8.9 10.2 0.2 11.4 3.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Macoilin PF09726.4 EIM80905.1 - 3.4 5.8 10.1 6.1 4.9 7.0 1.3 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EIM80905.1 - 6.3 6.3 13.3 13 5.3 9.3 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EIM80905.1 - 6.3 5.6 11.8 11 4.7 7.8 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-H PF05837.7 EIM80905.1 - 9.7 6.4 11.6 22 5.2 1.1 2.8 1 1 0 2 2 2 0 Centromere protein H (CENP-H) F-box PF00646.28 EIM80907.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM80907.1 - 0.0061 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like SgrR_N PF12793.2 EIM80907.1 - 0.051 13.5 0.7 0.089 12.8 0.5 1.3 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term Metallophos PF00149.23 EIM80908.1 - 7.2e-08 32.0 5.3 1.4e-07 31.1 3.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM80908.1 - 0.042 13.6 0.1 0.09 12.6 0.1 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF3832 PF12909.2 EIM80909.1 - 0.068 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) Abhydrolase_6 PF12697.2 EIM80911.1 - 0.00021 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM80911.1 - 0.00048 19.9 0.0 0.00054 19.7 0.0 1.1 1 0 0 1 1 1 1 Putative lysophospholipase DDE_3 PF13358.1 EIM80914.1 - 1.1e-10 41.4 0.0 2.5e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 DDE superfamily endonuclease Acetyltransf_1 PF00583.19 EIM80915.1 - 2.2e-09 37.2 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM80915.1 - 5.7e-08 32.8 0.0 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM80915.1 - 8.7e-05 22.6 0.0 0.00013 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM80915.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein TPR_MLP1_2 PF07926.7 EIM80916.1 - 0.00095 18.9 8.0 0.0038 16.9 5.5 1.9 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein SYCE1 PF15233.1 EIM80916.1 - 0.012 15.5 6.7 0.24 11.3 0.8 2.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 zf-C2H2 PF00096.21 EIM80916.1 - 0.072 13.4 0.2 0.072 13.4 0.1 3.2 3 1 0 3 3 3 0 Zinc finger, C2H2 type DUF1635 PF07795.6 EIM80916.1 - 5.7 6.2 9.2 9.4 5.5 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) F-box-like PF12937.2 EIM80918.1 - 5.1e-05 22.8 1.3 8.2e-05 22.2 0.3 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM80918.1 - 0.025 14.2 0.3 0.092 12.4 0.2 2.0 1 0 0 1 1 1 0 F-box domain Acetyltransf_3 PF13302.1 EIM80919.1 - 6.3e-18 65.3 0.0 7.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM80919.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain APH PF01636.18 EIM80920.1 - 6.2e-16 58.8 0.0 8.6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM80920.1 - 3.8e-05 23.3 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EIM80920.1 - 0.012 14.2 0.0 0.059 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EIM80920.1 - 0.056 12.5 0.0 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 EIM80920.1 - 0.14 11.2 0.0 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase K_trans PF02705.11 EIM80921.1 - 2.2e-163 544.4 16.2 2.7e-163 544.1 11.2 1.1 1 0 0 1 1 1 1 K+ potassium transporter APH PF01636.18 EIM80922.1 - 6.3e-19 68.6 0.0 7.1e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM80922.1 - 1.4e-05 24.7 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EIM80922.1 - 0.0061 15.2 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 EIM80922.1 - 0.074 12.1 0.0 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 EIM80922.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase DUF4073 PF13285.1 EIM80923.1 - 0.046 13.1 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Leucyl-specific PF14795.1 EIM80924.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain TAF8_C PF10406.4 EIM80925.1 - 0.0083 16.1 0.5 0.043 13.8 0.0 2.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CBM_1 PF00734.13 EIM80926.1 - 5.4e-13 48.3 15.5 1.5e-12 46.9 10.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 EIM80926.1 - 6.4e-07 29.4 1.5 1.1e-06 28.6 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CsbD PF05532.7 EIM80928.1 - 1.5e-06 27.7 10.0 3.5e-06 26.5 1.4 2.7 1 1 1 2 2 2 2 CsbD-like NAD_binding_4 PF07993.7 EIM80929.1 - 5.8e-34 117.1 0.0 9.4e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM80929.1 - 8.8e-31 106.7 0.0 2e-30 105.5 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM80929.1 - 3.4e-15 56.1 0.0 6.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM80929.1 - 4.8e-06 25.4 0.0 8.9e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EIM80929.1 - 1.9e-05 24.8 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EIM80929.1 - 0.00074 18.4 0.0 0.0074 15.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIM80929.1 - 0.052 13.5 0.1 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding DapB_N PF01113.15 EIM80929.1 - 0.096 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PIF1 PF05970.9 EIM80931.1 - 2.9e-05 23.1 0.0 0.041 12.8 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase DUF1340 PF07067.6 EIM80931.1 - 0.11 11.6 0.3 0.44 9.6 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1340) Methyltransf_23 PF13489.1 EIM80933.1 - 4.8e-08 32.8 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM80933.1 - 0.0001 22.7 0.0 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM80933.1 - 0.00011 22.5 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM80933.1 - 0.00042 20.8 0.0 0.003 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM80933.1 - 0.0019 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIM80933.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EIM80933.1 - 0.023 13.8 0.0 0.19 10.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIM80933.1 - 0.11 12.5 0.0 0.52 10.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EIM80934.1 - 2.7e-17 62.5 39.6 2.7e-17 62.5 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EIM80935.1 - 1e-44 152.8 0.0 2.5e-44 151.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EIM80936.1 - 2.4e-20 72.8 5.4 2.4e-20 72.8 3.7 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EIM80937.1 - 1.1e-54 185.7 0.0 1.6e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM80938.1 - 3.8e-54 183.9 0.0 1.3e-53 182.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.10 EIM80940.1 - 1.3e-07 31.4 0.1 1.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Sec34-like family Acetyltransf_1 PF00583.19 EIM80941.1 - 9.6e-07 28.7 0.0 3.1e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM80941.1 - 7.8e-05 22.7 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM80941.1 - 0.0017 18.4 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM80941.1 - 0.0046 16.6 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EIM80941.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.26 EIM80943.1 - 0.0087 16.0 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Sds3 PF08598.6 EIM80946.1 - 0.13 11.7 8.3 0.14 11.6 1.1 2.2 1 1 1 2 2 2 0 Sds3-like TBPIP PF07106.8 EIM80946.1 - 1.9 8.0 7.1 0.34 10.4 2.1 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HDAC4_Gln PF12203.3 EIM80946.1 - 2 8.3 9.6 1.5 8.7 4.6 2.3 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 SKG6 PF08693.5 EIM80953.1 - 2e-05 23.7 0.3 5.4e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EIM80953.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.7 EIM80953.1 - 0.92 9.3 0.0 0.92 9.3 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) AA_permease PF00324.16 EIM80954.1 - 5.4e-113 377.8 43.4 6e-113 377.7 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM80954.1 - 1.8e-33 115.6 48.6 2.2e-33 115.4 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3638 PF12340.3 EIM80956.1 - 9e-84 280.0 1.1 1.5e-83 279.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIM80956.1 - 3.5e-17 61.2 0.1 7.3e-17 60.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Jacalin PF01419.12 EIM80957.1 - 0.083 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain Cu-oxidase PF00394.17 EIM80961.1 - 9.7e-51 171.8 0.2 4.2e-44 150.2 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM80961.1 - 2.3e-38 130.8 1.7 2e-34 118.0 0.0 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM80961.1 - 5.3e-36 122.9 0.3 2.6e-34 117.4 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Ank PF00023.25 EIM80962.1 - 0.079 12.8 0.2 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Mfp-3 PF04202.8 EIM80963.1 - 0.089 12.9 0.0 23 5.2 0.0 2.3 2 0 0 2 2 2 0 Foot protein 3 Ribosomal_L2_C PF03947.13 EIM80963.1 - 0.1 12.3 6.0 0.44 10.3 0.9 2.3 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain CHAD PF05235.9 EIM80963.1 - 0.12 11.9 13.7 0.87 9.1 1.4 2.2 2 0 0 2 2 2 0 CHAD domain Urease_beta PF00699.15 EIM80963.1 - 0.17 11.7 2.2 6.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Urease beta subunit PP1_inhibitor PF05361.7 EIM80963.1 - 0.34 10.5 9.2 3.7 7.2 0.9 2.5 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor DUF4129 PF13559.1 EIM80963.1 - 8.7 6.3 11.2 18 5.3 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) DUF4449 PF14613.1 EIM80964.1 - 1.1e-08 35.2 2.2 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) zf-HIT PF04438.11 EIM80965.1 - 0.91 9.2 6.0 1.9 8.1 0.8 2.4 2 0 0 2 2 2 0 HIT zinc finger DUF2348 PF09807.4 EIM80966.1 - 1.9e-13 50.1 0.0 4.3e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Bd3614_N PF14442.1 EIM80966.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal MAP PF03642.8 EIM80967.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 MAP domain SAB PF04382.8 EIM80967.1 - 0.17 11.6 6.7 3.1 7.5 0.2 3.7 3 0 0 3 3 3 0 SAB domain HPPK PF01288.15 EIM80967.1 - 2.6 7.8 11.1 2.9 7.6 1.0 2.9 2 1 1 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF4544 PF15077.1 EIM80967.1 - 3.5 7.0 7.3 0.35 10.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) PWWP PF00855.12 EIM80969.1 - 1.9e-17 63.2 0.1 1.9e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 PWWP domain F-box-like PF12937.2 EIM80971.1 - 5.7e-05 22.7 0.0 0.00022 20.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM80971.1 - 0.0078 15.8 0.5 0.0078 15.8 0.3 3.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM80971.1 - 0.47 10.6 9.0 1.4 9.2 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat p450 PF00067.17 EIM80972.1 - 4.3e-59 200.2 0.0 6.4e-58 196.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.15 EIM80973.1 - 2.1e-12 47.3 0.1 6.6e-12 45.7 0.1 1.8 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TRAP_alpha PF03896.11 EIM80974.1 - 0.2 10.6 3.2 0.25 10.2 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zn_clus PF00172.13 EIM80976.1 - 4.8e-09 35.9 14.4 4.8e-09 35.9 10.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2547 PF10818.3 EIM80976.1 - 5.1 7.7 14.7 12 6.5 8.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Cys_Met_Meta_PP PF01053.15 EIM80977.1 - 2.2e-23 82.2 0.0 3e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-RING_3 PF14369.1 EIM80978.1 - 0.029 14.3 4.6 0.029 14.3 3.2 2.3 2 1 1 3 3 3 0 zinc-finger Cys_rich_CPCC PF14206.1 EIM80978.1 - 0.079 12.5 1.3 0.15 11.6 0.9 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC UPF0547 PF10571.4 EIM80978.1 - 1.7 8.3 5.4 4.5 7.0 3.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Metallophos_2 PF12850.2 EIM80979.1 - 9.2e-07 28.8 0.0 2.4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIM80979.1 - 2.2e-06 27.2 2.0 2.5e-05 23.7 1.4 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mem_trans PF03547.13 EIM80981.1 - 1.3e-26 92.8 5.4 5.4e-25 87.4 3.7 2.2 1 1 0 1 1 1 1 Membrane transport protein Lipase_GDSL PF00657.17 EIM80983.1 - 1.2e-14 54.6 2.2 2.2e-14 53.8 1.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIM80983.1 - 8.8e-11 42.2 2.7 1.2e-10 41.8 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MMtag PF10159.4 EIM80984.1 - 9.2e-30 102.5 3.7 9.2e-30 102.5 2.6 3.3 3 1 0 3 3 3 1 Kinase phosphorylation protein NARP1 PF12569.3 EIM80984.1 - 0.97 8.1 14.1 1.8 7.2 9.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_H2-Ydr279 PF09468.5 EIM80984.1 - 3.2 6.8 6.2 5.1 6.2 4.3 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Glyco_hydro_92 PF07971.7 EIM80985.1 - 9.5e-146 486.3 5.3 1.5e-145 485.7 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 zf-MYND PF01753.13 EIM80986.1 - 0.019 14.8 4.2 0.035 13.9 2.9 1.4 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.13 EIM80987.1 - 1.2e-12 47.5 12.0 1.7e-12 46.9 8.3 1.3 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.13 EIM80989.1 - 4.4e-10 38.8 0.0 7.6e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80989.1 - 2.2e-08 33.8 9.2 3.7e-08 33.1 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_P_40 PF08584.6 EIM80991.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Pkinase PF00069.20 EIM80992.1 - 1.4e-61 207.9 0.0 1.3e-60 204.7 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM80992.1 - 6e-38 130.4 0.0 5.3e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM80992.1 - 2.8e-06 26.4 0.0 4.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM80992.1 - 0.52 9.9 0.0 0.52 9.9 0.0 4.5 5 0 0 5 5 5 0 Phosphotransferase enzyme family zf-MYND PF01753.13 EIM80993.1 - 0.025 14.4 4.2 0.047 13.5 2.9 1.5 1 0 0 1 1 1 0 MYND finger Hydrolase_6 PF13344.1 EIM80994.1 - 1.6e-22 79.3 0.0 2.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM80994.1 - 2.2e-21 75.3 0.0 4.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM80994.1 - 1.4e-05 25.6 0.0 0.015 15.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM80994.1 - 0.00097 19.4 0.0 0.24 11.6 0.0 2.8 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EIM80995.1 - 4e-09 35.7 0.0 7.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM80995.1 - 2.7e-06 27.1 4.9 4.6e-06 26.4 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med12-PQL PF12144.3 EIM80995.1 - 0.016 14.6 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain LRR_4 PF12799.2 EIM80997.1 - 0.0033 17.0 2.3 32 4.2 0.1 5.6 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) Glyco_hydro_28 PF00295.12 EIM80998.1 - 6.4e-55 186.3 25.2 8.3e-55 186.0 17.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM80998.1 - 1.7e-10 40.8 24.3 1.7e-10 40.8 16.8 2.5 2 1 0 2 2 2 2 Right handed beta helix region DUF1565 PF07602.6 EIM80998.1 - 1.3e-06 27.7 17.4 1.7e-05 24.1 11.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) NosD PF05048.8 EIM80998.1 - 3.6e-05 23.0 14.2 3.6e-05 23.0 9.8 2.2 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) SMC_N PF02463.14 EIM80999.1 - 7.3e-70 234.6 0.2 1.1e-69 234.0 0.1 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIM80999.1 - 3.1e-26 91.6 0.2 1.2e-25 89.8 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIM80999.1 - 1.6e-15 57.8 3.4 1.7e-07 31.5 0.1 3.1 2 2 1 3 3 3 2 AAA domain AAA_23 PF13476.1 EIM80999.1 - 3.2e-14 53.7 29.6 3.2e-14 53.7 20.5 6.0 2 2 0 3 3 1 1 AAA domain AAA_15 PF13175.1 EIM80999.1 - 4.9e-14 52.2 5.5 8.5e-10 38.2 0.9 3.1 3 1 0 3 3 3 2 AAA ATPase domain Reo_sigmaC PF04582.7 EIM80999.1 - 4.2e-05 22.8 16.5 0.36 9.9 0.6 5.4 3 2 1 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EIM80999.1 - 0.0006 19.2 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 EIM80999.1 - 0.0019 18.0 17.0 0.0019 18.0 11.8 7.9 2 2 4 6 6 5 1 Tropomyosin like DUF4200 PF13863.1 EIM80999.1 - 0.0069 16.3 2.7 0.0069 16.3 1.9 9.5 3 3 5 9 9 8 1 Domain of unknown function (DUF4200) DUF1940 PF09155.5 EIM80999.1 - 0.023 14.5 6.2 0.88 9.3 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) Val_tRNA-synt_C PF10458.4 EIM80999.1 - 0.1 12.6 0.2 0.1 12.6 0.1 7.7 8 0 0 8 8 6 0 Valyl tRNA synthetase tRNA binding arm ABC_tran PF00005.22 EIM80999.1 - 0.15 12.3 0.1 0.15 12.3 0.1 5.3 2 2 1 3 3 2 0 ABC transporter Matrilin_ccoil PF10393.4 EIM80999.1 - 0.29 10.5 7.4 1 8.8 0.1 4.3 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin UPF0184 PF03670.8 EIM80999.1 - 0.34 11.1 13.3 1.6 8.9 1.3 4.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) IncA PF04156.9 EIM80999.1 - 0.36 10.4 101.9 0.022 14.3 5.9 7.0 3 2 4 7 7 7 0 IncA protein AAA_13 PF13166.1 EIM80999.1 - 2 6.7 66.9 0.014 13.8 9.0 5.8 3 2 1 5 5 5 0 AAA domain DUF3533 PF12051.3 EIM81000.1 - 8e-84 281.5 21.8 5.1e-75 252.5 12.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) F-box-like PF12937.2 EIM81005.1 - 1.6e-06 27.7 0.1 4.8e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM81005.1 - 0.42 10.2 3.5 11 5.7 0.4 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3533 PF12051.3 EIM81006.1 - 9e-63 212.2 18.6 4e-48 164.0 11.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) FA_desaturase PF00487.19 EIM81007.1 - 1.9e-26 93.0 13.0 5.8e-26 91.4 9.0 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EIM81007.1 - 1.3e-18 65.9 0.8 2.1e-18 65.2 0.6 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Thymidylat_synt PF00303.14 EIM81008.1 - 2.1e-108 361.4 0.0 2.4e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF4282 PF14110.1 EIM81009.1 - 0.58 10.3 2.9 0.92 9.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) PP2C PF00481.16 EIM81010.1 - 3.7e-31 108.4 0.0 5.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIM81010.1 - 0.012 15.3 0.2 1.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) G-alpha PF00503.15 EIM81013.1 - 5.8e-44 150.3 0.0 6.9e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EIM81013.1 - 0.041 14.3 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 EIM81014.1 - 2.8e-128 427.9 0.1 3.4e-128 427.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM81014.1 - 2.1e-16 59.6 2.5 9.3e-12 44.5 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EIM81014.1 - 0.00032 21.1 0.2 0.15 12.5 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EIM81014.1 - 0.00046 19.4 3.5 0.006 15.7 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM81014.1 - 0.01 15.7 0.2 0.48 10.3 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EIM81014.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIM81014.1 - 0.033 13.6 0.1 5 6.5 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-CHC2 PF01807.15 EIM81014.1 - 0.099 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 EIM81014.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family p450 PF00067.17 EIM81015.1 - 5.5e-63 213.1 0.0 6.9e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CysG_dimeriser PF10414.4 EIM81015.1 - 0.15 11.5 0.6 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Asp-B-Hydro_N PF05279.6 EIM81015.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sec2p PF06428.6 EIM81016.1 - 0.00076 19.2 1.1 0.00076 19.2 0.8 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p HAUS6_N PF14661.1 EIM81016.1 - 0.0028 17.0 0.2 0.0062 15.9 0.2 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.1 EIM81016.1 - 0.03 14.7 1.4 0.069 13.6 0.0 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HOOK PF05622.7 EIM81016.1 - 0.13 10.0 9.7 0.057 11.2 1.2 2.0 2 0 0 2 2 2 0 HOOK protein RsbRD_N PF14361.1 EIM81016.1 - 0.35 11.3 4.1 8.3 6.9 0.4 3.1 3 1 1 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain TBPIP PF07106.8 EIM81016.1 - 1.5 8.3 9.4 0.36 10.3 1.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIM81016.1 - 2.2 8.6 7.5 6.4 7.1 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WEMBL PF05701.6 EIM81016.1 - 2.6 6.3 10.7 0.77 8.1 3.8 1.9 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Rootletin PF15035.1 EIM81016.1 - 6.7 6.6 11.2 1.4 8.8 0.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cyt-b5 PF00173.23 EIM81018.1 - 1.1e-11 44.3 0.1 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNA_pol_Rpb5_C PF01191.14 EIM81018.1 - 0.023 14.2 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain CVNH PF08881.5 EIM81019.1 - 4.2e-05 23.7 0.0 7.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 CVNH domain OATP PF03137.15 EIM81022.1 - 0.15 10.0 0.0 0.26 9.3 0.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.20 EIM81024.1 - 4.3e-13 49.5 0.3 8.1e-13 48.6 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM81024.1 - 1.6e-05 24.6 0.1 2.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM81024.1 - 0.0001 22.1 0.3 0.00018 21.3 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIM81024.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1156 PF06634.7 EIM81024.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Pkinase PF00069.20 EIM81026.1 - 3.1e-32 111.7 0.0 5.4e-32 110.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81026.1 - 2.2e-08 33.4 0.0 0.0038 16.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 EIM81027.1 - 3e-31 108.5 0.0 4.4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81027.1 - 1.8e-09 37.0 0.0 1.2e-06 27.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kelch_4 PF13418.1 EIM81032.1 - 0.0047 16.6 0.0 0.0095 15.6 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain zf-MYND PF01753.13 EIM81034.1 - 3e-07 30.1 12.4 7.5e-07 28.9 8.6 1.7 1 0 0 1 1 1 1 MYND finger LRR_4 PF12799.2 EIM81036.1 - 5.1e-05 22.7 0.0 2.1 8.0 0.0 4.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM81036.1 - 6.3e-05 22.6 0.1 0.00018 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 EIM81037.1 - 1e-65 222.1 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.1 EIM81039.1 - 3.7e-23 82.5 0.0 5.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIM81039.1 - 4.2e-08 33.0 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM81039.1 - 3.3e-06 26.4 0.0 1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EIM81039.1 - 0.00036 20.2 5.1 0.00064 19.4 3.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 IBR PF01485.16 EIM81045.1 - 7.3e-15 54.5 39.1 6.8e-10 38.6 10.7 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EIM81045.1 - 9.6e-06 25.5 5.2 9.6e-06 25.5 3.6 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM81045.1 - 0.00014 21.4 5.5 0.00014 21.4 3.8 4.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM81045.1 - 0.00017 21.3 5.9 0.00017 21.3 4.1 3.7 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 EIM81045.1 - 0.00079 19.0 4.4 0.00079 19.0 3.0 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM81045.1 - 0.0047 16.7 2.1 0.0047 16.7 1.5 4.4 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM81045.1 - 0.012 15.2 5.3 0.012 15.2 3.7 3.9 4 1 0 4 4 4 0 zinc-RING finger domain DUF721 PF05258.7 EIM81046.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF721) p450 PF00067.17 EIM81048.1 - 2.4e-52 178.0 0.1 5.3e-34 117.5 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 AA_permease PF00324.16 EIM81052.1 - 2.9e-122 408.4 40.2 3.3e-122 408.2 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM81052.1 - 1.6e-37 129.1 46.4 1.9e-37 128.8 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EIM81052.1 - 0.089 12.3 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Pkinase PF00069.20 EIM81053.1 - 0.00031 19.9 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM81053.1 - 0.0041 16.8 0.2 0.0085 15.8 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM81053.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 EIM81053.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 EIM81053.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.15 EIM81055.1 - 2.7e-161 537.5 4.1 3.9e-161 536.9 0.0 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EIM81055.1 - 1.9e-09 36.5 0.0 7.3e-09 34.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.20 EIM81056.1 - 1.2e-61 208.1 0.0 1.7e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81056.1 - 7.7e-32 110.3 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIM81056.1 - 3e-15 56.0 0.2 6.2e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EIM81056.1 - 4e-08 32.5 0.1 2.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM81056.1 - 0.0018 18.0 0.0 0.13 11.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM81056.1 - 0.0019 17.2 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Alpha_GJ PF03229.8 EIM81056.1 - 0.13 12.6 2.6 0.33 11.2 0.9 2.4 3 0 0 3 3 3 0 Alphavirus glycoprotein J F-box PF00646.28 EIM81057.1 - 0.0019 17.7 0.0 0.006 16.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.19 EIM81058.1 - 7.2e-05 22.7 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM81058.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM81058.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM81058.1 - 0.063 13.1 0.1 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIM81058.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Mannosyl_trans PF05007.8 EIM81059.1 - 0.0029 17.2 1.0 0.0029 17.2 0.7 1.4 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) Acyl-ACP_TE PF01643.12 EIM81060.1 - 0.078 11.8 0.7 0.12 11.2 0.1 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase DUF3328 PF11807.3 EIM81061.1 - 2.7e-38 131.8 0.1 3.1e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PC-Esterase PF13839.1 EIM81062.1 - 8.7e-08 32.2 0.0 7e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AAA_16 PF13191.1 EIM81063.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EIM81063.1 - 0.041 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DAP3 PF10236.4 EIM81063.1 - 0.062 12.2 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 EIM81063.1 - 0.068 12.9 0.0 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EIM81063.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EIM81063.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Lyase_aromatic PF00221.14 EIM81064.1 - 1.6e-155 518.1 3.2 1.9e-155 517.9 2.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase F-box-like PF12937.2 EIM81065.1 - 1.7e-07 30.8 0.5 3e-07 30.0 0.2 1.5 2 0 0 2 2 2 1 F-box-like DUF2562 PF10814.3 EIM81066.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) LRR_4 PF12799.2 EIM81066.1 - 6.9 6.4 14.8 23 4.7 0.8 5.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Sugar_tr PF00083.19 EIM81067.1 - 3.1e-87 293.0 26.6 3.5e-87 292.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM81067.1 - 1.6e-29 102.7 34.9 4.8e-20 71.5 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM81067.1 - 0.29 9.4 40.5 0.0062 14.9 3.9 3.7 2 2 1 3 3 3 0 MFS/sugar transport protein Peptidase_M24 PF00557.19 EIM81069.1 - 6.7e-40 136.8 0.0 9.4e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIM81069.1 - 3.5e-20 72.8 0.0 2.6e-19 70.0 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain NOG1 PF06858.9 EIM81070.1 - 3.8e-28 97.1 0.1 7.1e-28 96.2 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EIM81070.1 - 6.2e-28 96.2 1.6 6.2e-28 96.2 1.1 2.3 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EIM81070.1 - 5.8e-17 61.7 0.0 1.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM81070.1 - 1.1e-08 34.4 0.0 2.6e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIM81070.1 - 0.00055 20.4 0.0 0.0016 18.8 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EIM81070.1 - 0.0048 16.1 0.0 0.047 12.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIM81070.1 - 0.066 13.0 0.0 2.6 7.8 0.0 2.6 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.15 EIM81071.1 - 1.4e-114 382.7 0.0 1.7e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM81071.1 - 1.7e-09 37.1 0.0 2.4e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM81071.1 - 0.0099 15.0 1.6 0.86 8.6 0.0 2.9 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region DAP3 PF10236.4 EIM81071.1 - 0.034 13.0 0.9 0.068 12.0 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 EIM81071.1 - 0.044 13.3 0.3 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 EIM81071.1 - 0.1 12.2 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DASH_Dad4 PF08650.5 EIM81073.1 - 1.4e-16 60.1 1.1 1.6e-16 59.9 0.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Ig_J_chain PF15097.1 EIM81073.1 - 0.071 12.7 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin J chain WD40 PF00400.27 EIM81074.1 - 0.0016 18.2 3.1 9.7 6.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3356 PF11836.3 EIM81074.1 - 0.13 12.1 0.2 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) Methyltransf_2 PF00891.13 EIM81075.1 - 1.3e-18 67.0 0.0 7.4e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_16 PF10294.4 EIM81075.1 - 0.0013 18.1 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MarR PF01047.17 EIM81075.1 - 0.016 14.8 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 MarR family TrmB PF01978.14 EIM81075.1 - 0.09 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_31 PF13847.1 EIM81075.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 EIM81076.1 - 9.9e-08 31.5 0.1 2.9e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81076.1 - 0.0037 16.8 2.2 0.018 14.7 0.1 3.1 3 0 0 3 3 3 1 F-box domain Rap1-DNA-bind PF09197.5 EIM81077.1 - 1.6e-05 25.3 6.3 0.031 14.8 0.7 3.4 2 1 1 3 3 3 3 Rap1, DNA-binding BRCT PF00533.21 EIM81077.1 - 8.5e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RhoGEF PF00621.15 EIM81079.1 - 7.6e-39 133.4 2.3 1.1e-38 132.8 1.6 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EIM81079.1 - 5.8e-33 113.5 0.0 1.2e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EIM81079.1 - 2.9e-13 49.2 0.0 5.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 EIM81079.1 - 1.9e-11 43.8 0.0 3.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PH PF00169.24 EIM81079.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 PH domain SelP_N PF04592.9 EIM81079.1 - 0.91 8.8 8.4 2 7.7 5.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PduV-EutP PF10662.4 EIM81080.1 - 1.1e-05 24.9 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EIM81080.1 - 3e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIM81080.1 - 0.00026 21.4 0.0 0.00092 19.6 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EIM81080.1 - 0.0015 19.3 0.1 0.0026 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 EIM81080.1 - 0.0026 17.0 0.0 0.0062 15.7 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MobB PF03205.9 EIM81080.1 - 0.0028 17.3 0.0 0.0077 15.9 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EIM81080.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EIM81080.1 - 0.0088 15.0 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 1 Septin G-alpha PF00503.15 EIM81080.1 - 0.0089 14.7 0.0 0.048 12.3 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit DUF258 PF03193.11 EIM81080.1 - 0.017 14.2 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM81080.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EIM81080.1 - 0.031 13.8 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIM81080.1 - 0.031 13.6 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIM81080.1 - 0.056 13.7 0.0 0.089 13.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Mito_carr PF00153.22 EIM81084.1 - 4.5e-74 244.2 0.0 1.3e-26 92.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_4 PF01565.18 EIM81086.1 - 0.0049 16.3 6.1 0.73 9.2 0.3 3.2 2 1 0 2 2 2 2 FAD binding domain Glyco_hydro_63 PF03200.11 EIM81088.1 - 2.9e-07 28.7 7.1 3.9e-06 25.0 0.4 3.8 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase AAA_22 PF13401.1 EIM81089.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EIM81089.1 - 0.085 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_19 PF13245.1 EIM81089.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EIM81089.1 - 0.12 12.3 0.2 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 EIM81089.1 - 0.13 11.1 0.0 0.34 9.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RhoGAP PF00620.22 EIM81090.1 - 8.3e-29 100.1 0.0 3.2e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EIM81091.1 - 0.17 11.8 1.5 3.2 7.7 0.0 2.9 3 0 0 3 3 3 0 MyTH4 domain MFS_1 PF07690.11 EIM81092.1 - 1.3e-44 152.4 47.6 1.8e-44 151.9 33.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81092.1 - 1.2e-18 66.9 32.3 8.1e-18 64.2 6.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EIM81092.1 - 2.1e-13 49.3 23.1 3.9e-13 48.4 16.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EIM81092.1 - 0.00013 20.5 3.9 0.00013 20.5 2.7 2.9 1 1 1 2 2 2 1 MFS/sugar transport protein DUF106 PF01956.11 EIM81092.1 - 1.4 8.3 7.3 2 7.9 0.1 2.6 1 1 1 2 2 2 0 Integral membrane protein DUF106 AAA_19 PF13245.1 EIM81093.1 - 0.00054 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM81093.1 - 0.0039 17.3 0.1 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIM81093.1 - 0.0055 16.1 1.2 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EIM81093.1 - 0.007 16.3 0.4 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIM81093.1 - 0.011 15.2 0.6 0.052 13.0 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EIM81093.1 - 0.017 15.9 0.2 0.1 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIM81093.1 - 0.023 15.0 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EIM81093.1 - 0.029 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIM81093.1 - 0.034 13.5 0.2 0.072 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EIM81093.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EIM81093.1 - 0.057 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 EIM81093.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM81093.1 - 0.078 13.2 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EIM81093.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_11 PF13086.1 EIM81093.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain RPEL PF02755.10 EIM81095.1 - 9.3e-14 50.2 5.5 9.8e-08 31.0 0.7 2.5 2 0 0 2 2 2 2 RPEL repeat IDEAL PF08858.5 EIM81095.1 - 0.032 13.7 1.0 0.084 12.3 0.7 1.7 1 0 0 1 1 1 0 IDEAL domain MEA1 PF06910.6 EIM81095.1 - 0.036 13.7 0.3 0.046 13.3 0.2 1.1 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) Sigma70_r3 PF04539.11 EIM81095.1 - 0.7 9.8 4.9 4.3 7.2 0.7 2.2 1 1 1 2 2 2 0 Sigma-70 region 3 DUF1279 PF06916.8 EIM81096.1 - 4.1e-15 55.8 0.0 1e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Zn_clus PF00172.13 EIM81097.1 - 2.4e-08 33.7 29.4 9e-05 22.3 5.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_capsid PF06112.6 EIM81097.1 - 0.9 9.5 8.3 0.24 11.4 3.2 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Dfp1_Him1_M PF08630.5 EIM81099.1 - 9.3e-23 80.3 0.0 9.3e-23 80.3 0.0 2.2 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.7 EIM81099.1 - 1.6e-20 72.4 0.7 3.1e-20 71.5 0.5 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EIM81099.1 - 0.00062 19.8 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIM81099.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain DUF3505 PF12013.3 EIM81100.1 - 0.0047 17.1 10.7 4.2 7.6 0.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF3505) zf-C3HC PF07967.8 EIM81100.1 - 0.046 13.4 1.8 13 5.5 0.0 3.6 4 0 0 4 4 4 0 C3HC zinc finger-like Mut7-C PF01927.11 EIM81100.1 - 0.068 13.1 1.1 22 4.9 0.0 3.3 3 0 0 3 3 3 0 Mut7-C RNAse domain DUF3797 PF12677.2 EIM81100.1 - 0.17 11.5 1.5 29 4.3 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) zf-Di19 PF05605.7 EIM81100.1 - 0.19 11.9 17.7 7.7 6.7 0.1 5.1 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 EIM81100.1 - 0.45 10.7 7.7 19 5.4 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) DUF3342 PF11822.3 EIM81100.1 - 0.62 9.1 3.3 20 4.1 0.5 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3342) Rubredoxin PF00301.15 EIM81100.1 - 0.74 9.7 4.6 16 5.4 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin DNA_RNApol_7kD PF03604.8 EIM81100.1 - 0.76 9.2 18.6 0.36 10.3 0.1 4.8 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit zf-C4_Topoisom PF01396.14 EIM81100.1 - 1.1 8.8 12.0 1.5 8.3 0.1 4.0 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-RING_3 PF14369.1 EIM81100.1 - 3.1 7.8 8.7 35 4.4 0.2 4.2 4 0 0 4 4 4 0 zinc-finger zinc_ribbon_5 PF13719.1 EIM81100.1 - 3.6 7.2 15.3 4.9 6.8 0.0 5.2 5 0 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM81100.1 - 6 6.6 15.7 6.2 6.6 0.0 5.2 5 0 0 5 5 5 0 zinc-ribbon domain RmlD_sub_bind PF04321.12 EIM81101.1 - 7.4e-53 179.2 0.0 9.1e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIM81101.1 - 2e-21 76.5 0.0 2.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIM81101.1 - 1.4e-08 34.0 0.0 4.3e-07 29.1 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EIM81101.1 - 7.4e-05 21.7 0.0 0.0027 16.6 0.0 2.6 1 1 1 3 3 3 1 Male sterility protein DapB_N PF01113.15 EIM81101.1 - 0.0078 16.1 0.1 0.072 13.0 0.0 2.4 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Orbi_VP6 PF01516.11 EIM81103.1 - 0.29 10.1 2.6 0.42 9.6 1.8 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 HAUS6_N PF14661.1 EIM81103.1 - 2.6 7.3 8.6 4 6.7 6.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4047 PF13256.1 EIM81103.1 - 6.8 6.6 6.3 11 5.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) RNase_H2-Ydr279 PF09468.5 EIM81103.1 - 7.8 5.5 7.5 8.7 5.4 4.4 1.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) PP2C PF00481.16 EIM81104.1 - 1.6e-23 83.3 0.0 8.1e-22 77.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIM81104.1 - 0.00011 21.6 0.0 0.00042 19.7 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIM81104.1 - 0.061 13.0 0.1 4.1 7.0 0.0 2.7 2 1 1 3 3 3 0 Stage II sporulation protein E (SpoIIE) SAM_decarbox PF01536.11 EIM81105.1 - 1e-75 254.4 0.0 2.5e-49 167.7 0.0 3.8 3 1 0 3 3 3 3 Adenosylmethionine decarboxylase zf-C2H2_2 PF12756.2 EIM81108.1 - 9.6e-35 118.7 12.2 2.2e-29 101.5 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIM81108.1 - 5.1e-09 36.0 1.5 5.1e-09 36.0 1.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM81108.1 - 3.5e-08 33.3 2.2 3.5e-08 33.3 1.5 3.9 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIM81108.1 - 0.0002 21.4 12.8 0.0038 17.4 0.3 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIM81108.1 - 0.00046 19.9 6.6 0.0018 18.0 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM81108.1 - 0.031 14.6 0.8 0.031 14.6 0.6 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Spore_coat_CotO PF14153.1 EIM81108.1 - 0.32 10.4 11.9 0.14 11.5 4.2 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Pox_Ag35 PF03286.9 EIM81108.1 - 1.9 7.9 17.4 0.043 13.3 5.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Rax2 PF12768.2 EIM81109.1 - 3.3e-81 272.5 41.6 1.2e-70 237.9 5.3 6.3 6 2 1 7 7 7 3 Cortical protein marker for cell polarity SH3_1 PF00018.23 EIM81109.1 - 2.7e-09 36.2 0.0 5.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM81109.1 - 6.6e-07 28.8 0.1 1.7e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.1 EIM81109.1 - 0.00066 19.7 16.3 0.29 11.3 0.1 6.7 5 1 1 6 6 6 2 Kelch motif SH3_2 PF07653.12 EIM81109.1 - 0.00087 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ABC_membrane_3 PF13748.1 EIM81109.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4083 PF13314.1 EIM81109.1 - 0.16 11.8 1.1 0.39 10.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) EphA2_TM PF14575.1 EIM81109.1 - 0.28 11.5 0.0 0.76 10.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Dimer_Tnp_Tn5 PF02281.11 EIM81109.1 - 1.6 8.9 4.7 16 5.6 0.2 3.4 3 0 0 3 3 3 0 Transposase Tn5 dimerisation domain TPR_11 PF13414.1 EIM81110.1 - 1.6e-15 56.4 0.7 9e-15 54.0 0.2 2.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIM81110.1 - 1.4e-09 37.1 0.7 0.001 18.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM81110.1 - 2.1e-06 27.0 0.1 0.063 12.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.23 EIM81110.1 - 1.5e-05 25.3 0.1 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 SET domain TPR_16 PF13432.1 EIM81110.1 - 0.00028 21.4 1.7 0.63 10.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM81110.1 - 0.00038 20.3 1.3 0.023 14.6 0.4 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM81110.1 - 0.002 18.4 0.0 0.0045 17.3 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM81110.1 - 0.022 14.5 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM81110.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EIM81110.1 - 0.15 12.8 1.2 6 7.8 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TP6A_N PF04406.9 EIM81111.1 - 6.6e-21 73.7 0.0 1.2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Rax2 PF12768.2 EIM81112.1 - 0.00055 19.2 0.0 0.00081 18.6 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF4381 PF14316.1 EIM81112.1 - 0.13 12.3 0.1 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1517 PF07466.6 EIM81112.1 - 0.42 9.5 5.6 0.1 11.5 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Lamp PF01299.12 EIM81112.1 - 4.3 6.3 8.3 0.38 9.8 0.6 2.3 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Transpep_BrtH PF14399.1 EIM81113.1 - 0.0088 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase BTB PF00651.26 EIM81113.1 - 0.026 14.5 0.8 0.099 12.6 0.6 1.9 1 1 0 1 1 1 0 BTB/POZ domain AAA_22 PF13401.1 EIM81114.1 - 5.8e-12 45.8 0.0 3.8e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIM81114.1 - 9.7e-10 38.7 0.1 4.2e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM81114.1 - 6e-07 29.6 0.1 7.4e-05 22.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EIM81114.1 - 6.5e-05 22.6 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EIM81114.1 - 0.00034 20.3 0.0 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EIM81114.1 - 0.00039 19.3 0.1 0.00066 18.6 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EIM81114.1 - 0.0015 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM81114.1 - 0.0015 18.1 0.0 0.005 16.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EIM81114.1 - 0.0043 16.5 0.0 3.3 7.0 0.0 2.3 1 1 0 2 2 2 2 AAA-like domain cobW PF02492.14 EIM81114.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EIM81114.1 - 0.013 15.2 0.4 0.057 13.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EIM81114.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EIM81114.1 - 0.024 14.8 0.0 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EIM81114.1 - 0.031 14.7 0.2 0.086 13.3 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_2 PF07724.9 EIM81114.1 - 0.032 14.1 0.1 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 EIM81114.1 - 0.06 13.6 0.1 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 EIM81114.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EIM81114.1 - 0.093 12.1 0.8 0.94 8.8 0.3 2.5 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EIM81114.1 - 0.12 12.2 0.1 0.69 9.8 0.0 2.3 2 1 1 3 3 3 0 AAA domain MSC PF09402.5 EIM81114.1 - 0.17 10.5 0.2 0.28 9.8 0.2 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Spc97_Spc98 PF04130.8 EIM81116.1 - 3.8e-42 144.3 0.0 9.2e-42 143.0 0.0 1.7 1 1 0 1 1 1 1 Spc97 / Spc98 family BTB PF00651.26 EIM81117.1 - 0.00014 21.8 0.1 0.0012 18.8 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain DUF3435 PF11917.3 EIM81118.1 - 0.72 8.5 2.8 1 8.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) F-box-like PF12937.2 EIM81119.1 - 1.1e-05 25.0 0.1 8e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM81119.1 - 0.0078 15.8 2.1 11 5.8 0.0 4.8 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) HALZ PF02183.13 EIM81119.1 - 0.24 11.1 1.7 0.73 9.5 1.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper OPT PF03169.10 EIM81122.1 - 1.7e-163 545.4 40.7 2e-163 545.2 28.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Caveolin PF01146.12 EIM81122.1 - 3.2 7.3 8.0 1.2 8.7 0.1 2.8 2 0 0 2 2 2 0 Caveolin OSCP PF00213.13 EIM81123.1 - 1e-39 136.1 1.8 1.2e-39 135.9 1.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DNA_pol3_a_NI PF14480.1 EIM81123.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I SET PF00856.23 EIM81124.1 - 1.1e-14 55.0 0.4 1.9e-14 54.3 0.3 1.3 1 0 0 1 1 1 1 SET domain Notch PF00066.12 EIM81124.1 - 0.05 13.8 0.6 0.05 13.8 0.4 2.2 2 0 0 2 2 2 0 LNR domain KdpC PF02669.10 EIM81124.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain PIG-U PF06728.8 EIM81126.1 - 4.8e-108 361.4 23.3 6e-108 361.0 16.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TEX12 PF15219.1 EIM81126.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed 12 F-box-like PF12937.2 EIM81127.1 - 8.8e-05 22.1 1.2 0.00054 19.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM81127.1 - 0.00035 20.1 0.3 0.0011 18.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EIM81131.1 - 5.8e-15 54.8 9.5 5.8e-15 54.8 6.6 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2518 PF10726.4 EIM81131.1 - 0.066 12.7 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of function (DUF2518) Inhibitor_I9 PF05922.11 EIM81134.1 - 3.7e-08 33.8 0.0 4.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 HhH-GPD PF00730.20 EIM81135.1 - 5.4e-15 55.5 0.0 1.4e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SLAC1 PF03595.12 EIM81137.1 - 1.2e-82 277.2 46.6 1.3e-82 277.0 32.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PRA1 PF03208.14 EIM81141.1 - 2e-40 137.6 0.4 2.3e-40 137.4 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3040 PF11239.3 EIM81141.1 - 0.26 11.3 0.2 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ribosomal_60s PF00428.14 EIM81142.1 - 0.0034 17.7 0.3 0.0038 17.6 0.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein APC_CDC26 PF10471.4 EIM81142.1 - 0.025 15.3 0.2 0.037 14.7 0.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 TPR_11 PF13414.1 EIM81143.1 - 2.3e-20 71.9 3.1 1.9e-10 40.1 0.2 3.6 2 2 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EIM81143.1 - 7.7e-19 66.4 1.3 0.0049 16.4 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIM81143.1 - 1.6e-14 52.7 2.9 0.0036 17.3 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIM81143.1 - 8.2e-14 50.3 6.6 0.026 14.4 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM81143.1 - 1.6e-13 49.9 8.0 0.0065 17.0 0.0 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM81143.1 - 1.8e-12 47.5 4.5 2e-05 25.1 0.3 4.3 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM81143.1 - 7.9e-10 38.9 1.0 1.8e-05 24.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM81143.1 - 1.6e-09 37.5 0.8 0.0012 18.7 0.0 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIM81143.1 - 2.3e-07 30.8 3.3 0.0043 17.1 0.0 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM81143.1 - 1.3e-06 27.7 0.1 0.86 9.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIM81143.1 - 1.7e-06 28.0 0.1 0.0016 18.5 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM81143.1 - 0.00061 19.3 0.4 4.6 7.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIM81143.1 - 0.064 13.2 7.9 14 5.7 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM81143.1 - 0.07 12.9 3.8 0.92 9.4 0.2 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF1641 PF07849.6 EIM81143.1 - 0.32 10.6 1.2 29 4.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1641) TPR_6 PF13174.1 EIM81143.1 - 0.79 10.3 2.6 21 5.8 0.0 4.2 6 0 0 6 6 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EIM81144.1 - 5e-12 45.3 12.8 0.00016 21.7 0.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM81144.1 - 2.1e-11 43.2 12.0 0.00018 21.6 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM81144.1 - 7.2e-09 35.5 11.9 1.7e-06 28.0 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM81144.1 - 1.1e-05 25.1 1.9 0.1 12.5 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.13 EIM81144.1 - 0.0036 17.6 1.6 0.0036 17.6 1.1 2.2 1 1 0 2 2 2 1 TRAF-type zinc finger IBR PF01485.16 EIM81144.1 - 0.0036 17.1 7.9 0.069 13.0 3.3 2.2 1 1 1 2 2 2 1 IBR domain Rtf2 PF04641.7 EIM81144.1 - 0.033 13.3 0.7 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger zf-met PF12874.2 EIM81144.1 - 0.054 13.7 5.3 2.7 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EIM81144.1 - 0.064 13.3 4.3 0.83 9.8 1.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EIM81144.1 - 4 7.5 10.9 0.55 10.2 0.7 3.2 3 1 0 3 3 3 0 zinc-finger Zn-ribbon_8 PF09723.5 EIM81144.1 - 7.9 6.5 9.9 1.5e+02 2.4 0.0 3.2 2 1 0 2 2 2 0 Zinc ribbon domain Abhydrolase_3 PF07859.8 EIM81145.1 - 2e-27 96.1 0.0 1e-18 67.7 0.1 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Allantoicase PF03561.10 EIM81146.1 - 8.6e-89 294.7 0.0 2.8e-44 150.2 0.0 2.4 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 EIM81146.1 - 6.8e-42 142.6 0.0 1.1e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate hydrolase F5_F8_type_C PF00754.20 EIM81146.1 - 0.00067 19.4 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain Pheromone PF08015.6 EIM81146.1 - 7.3 7.5 8.8 21 6.0 3.3 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone UPF0183 PF03676.9 EIM81147.1 - 0.0074 14.9 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) DUF2749 PF10907.3 EIM81148.1 - 0.054 13.3 0.2 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Zn_clus PF00172.13 EIM81151.1 - 1.6e-05 24.6 10.6 2.6e-05 24.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIM81151.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIM81151.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 PAS domain Methyltransf_26 PF13659.1 EIM81152.1 - 7.2e-10 38.9 0.0 3.3e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81152.1 - 1.6e-06 28.6 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM81152.1 - 3.2e-06 26.8 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM81152.1 - 0.0035 17.6 0.0 0.0061 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM81152.1 - 0.0043 16.4 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_10 PF05971.7 EIM81152.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Peptidase_M17 PF00883.16 EIM81157.1 - 1.6e-115 385.2 0.0 2.4e-115 384.6 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EIM81157.1 - 1.8e-06 27.6 0.8 3.7e-06 26.6 0.6 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Alpha-L-AF_C PF06964.7 EIM81159.1 - 7.5e-40 136.5 0.2 1.6e-39 135.4 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EIM81159.1 - 0.11 12.5 8.9 0.025 14.5 1.1 2.7 3 0 0 3 3 3 0 Carbohydrate binding domain GFO_IDH_MocA PF01408.17 EIM81160.1 - 1.6e-23 83.4 0.1 3.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM81160.1 - 0.0016 18.8 0.2 0.0026 18.1 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EIM81160.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIM81160.1 - 0.044 14.0 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HMG_box PF00505.14 EIM81161.1 - 2.1e-08 34.3 3.2 2.6e-06 27.6 1.1 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM81161.1 - 0.0012 19.2 0.9 0.0018 18.5 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain Proteasome PF00227.21 EIM81162.1 - 3.3e-55 186.3 0.0 8e-55 185.0 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM81162.1 - 2.1e-14 52.4 0.2 4.2e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature F-box-like PF12937.2 EIM81163.1 - 1.3e-10 40.7 0.9 1.3e-10 40.7 0.6 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIM81163.1 - 1.2e-06 28.0 0.1 3.7e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ribosomal_L18p PF00861.17 EIM81163.1 - 0.0095 16.1 0.2 0.02 15.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family WD40 PF00400.27 EIM81164.1 - 2.3e-30 103.3 6.9 2.1e-07 30.5 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EIM81164.1 - 0.042 12.6 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Me-amine-dh_H PF06433.6 EIM81164.1 - 0.057 12.0 0.0 0.35 9.4 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) LSM PF01423.17 EIM81165.1 - 9.3e-15 53.9 0.1 1.3e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIM81165.1 - 0.091 12.6 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain F-box-like PF12937.2 EIM81166.1 - 7.4e-06 25.6 1.1 1.8e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like RRM_1 PF00076.17 EIM81169.1 - 1.9e-12 46.6 0.0 1.9e-05 24.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM81169.1 - 1.3e-08 34.6 0.0 0.00066 19.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM81169.1 - 4.6e-06 26.3 0.0 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Oxidored_FMN PF00724.15 EIM81170.1 - 4e-66 223.3 0.0 6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.14 EIM81171.1 - 2.4e-20 72.9 1.8 1.3e-14 54.0 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM81171.1 - 0.00022 20.2 0.0 0.0081 15.1 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EIM81171.1 - 0.00029 19.7 0.0 0.00087 18.1 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EIM81171.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM81171.1 - 0.097 13.0 0.9 5.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase G_glu_transpept PF01019.16 EIM81175.1 - 1.3e-153 512.1 0.0 1.5e-153 511.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3759 PF12585.3 EIM81177.1 - 0.043 13.7 0.3 0.082 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) adh_short PF00106.20 EIM81178.1 - 5.6e-24 84.9 0.6 1e-23 84.0 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81178.1 - 1.2e-12 48.1 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81178.1 - 9.5e-06 25.3 0.1 1.3e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 KR domain ApbA PF02558.11 EIM81178.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.5 EIM81178.1 - 0.035 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FNIP PF05725.7 EIM81178.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FNIP Repeat DUF563 PF04577.9 EIM81181.1 - 4e-19 69.3 0.0 2e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) PMP1_2 PF08114.6 EIM81181.1 - 0.16 11.4 0.1 7.5 6.1 0.1 2.4 2 0 0 2 2 2 0 ATPase proteolipid family Sec63 PF02889.11 EIM81181.1 - 0.23 10.6 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 Sec63 Brl domain Palm_thioest PF02089.10 EIM81182.1 - 5.7e-55 186.2 0.0 3.1e-47 160.8 0.0 2.0 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EIM81182.1 - 0.00036 20.4 0.1 0.00062 19.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM81182.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3421 PF11901.3 EIM81183.1 - 1.1e-24 86.4 0.1 7.5e-12 45.0 0.0 3.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) ABA_WDS PF02496.11 EIM81183.1 - 0.00026 21.1 3.5 0.0006 19.9 2.5 1.5 1 0 0 1 1 1 1 ABA/WDS induced protein DUF1974 PF09317.6 EIM81183.1 - 0.0024 17.3 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) CBM_5_12 PF02839.9 EIM81183.1 - 0.06 12.9 4.6 0.044 13.3 1.5 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain p450 PF00067.17 EIM81184.1 - 1.3e-66 225.0 0.0 4.1e-66 223.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EIM81185.1 - 9.2e-19 66.5 8.5 9.9e-07 28.4 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIM81185.1 - 0.0039 17.0 0.2 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleos_tra2_C PF07662.8 EIM81186.1 - 1.3e-67 227.3 3.9 1.3e-67 227.3 2.7 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIM81186.1 - 5.2e-16 58.7 5.5 5.2e-16 58.7 3.8 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EIM81186.1 - 0.012 15.5 8.2 0.012 15.5 5.7 3.1 3 0 0 3 3 3 0 Nucleoside recognition Abhydrolase_3 PF07859.8 EIM81188.1 - 1.4e-27 96.6 0.0 1.8e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM81188.1 - 3.1e-11 42.5 0.0 4.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIM81188.1 - 0.06 12.5 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thaumatin PF00314.12 EIM81189.1 - 2.7e-14 53.1 7.7 3.3e-14 52.8 5.4 1.1 1 0 0 1 1 1 1 Thaumatin family Pkinase PF00069.20 EIM81190.1 - 2.3e-63 213.7 0.0 2.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81190.1 - 7.8e-41 139.8 0.0 1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81190.1 - 2.1e-08 33.4 0.0 6.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM81190.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1485 PF07364.7 EIM81190.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Seadorna_VP7 PF07387.6 EIM81190.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med1 PF10744.4 EIM81191.1 - 0.00023 20.0 0.0 0.047 12.4 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 EIM81192.1 - 1.1e-58 198.4 0.0 1.5e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81192.1 - 1.3e-29 103.1 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81192.1 - 4.9e-08 32.2 0.0 1.6e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 EIM81192.1 - 7.2e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PH domain APH PF01636.18 EIM81192.1 - 0.014 15.1 0.1 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM81192.1 - 0.053 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ALS_ss_C PF10369.4 EIM81193.1 - 1.8e-20 72.4 0.6 1.5e-19 69.4 0.1 2.4 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EIM81193.1 - 2.8e-12 45.8 0.1 5.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EIM81193.1 - 1.9e-08 34.0 0.0 4.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF1989 PF09347.5 EIM81195.1 - 5.4e-54 182.0 0.0 6.6e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) COG5 PF10392.4 EIM81196.1 - 2.5e-27 95.4 0.0 8.8e-27 93.6 0.0 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EIM81196.1 - 0.00086 19.1 0.1 0.015 15.0 0.0 3.2 2 1 0 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 EIM81196.1 - 0.0057 15.6 0.0 0.029 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 EIM81196.1 - 0.013 15.1 0.2 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 EIM81196.1 - 0.028 14.2 3.0 0.24 11.2 0.1 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 EIM81196.1 - 0.037 13.4 0.1 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3508 PF12018.3 EIM81196.1 - 0.2 10.5 1.3 4.2 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) Cellulase PF00150.13 EIM81197.1 - 5.2e-31 107.8 4.6 6.8e-31 107.5 3.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EIM81197.1 - 1.9e-13 49.7 15.1 5.2e-13 48.4 10.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_1 PF00232.13 EIM81197.1 - 0.00094 17.4 0.1 0.0018 16.5 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase-like PF12876.2 EIM81197.1 - 0.0017 18.7 0.0 0.0052 17.2 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EIM81197.1 - 0.0022 16.9 0.0 0.0066 15.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_A22B PF04258.8 EIM81198.1 - 7.7e-68 229.1 1.1 9.5e-68 228.8 0.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EIM81198.1 - 9.6e-06 24.9 3.1 3.6e-05 23.0 2.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) UPF0233 PF06781.7 EIM81198.1 - 0.026 14.1 0.0 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) GATA PF00320.22 EIM81199.1 - 1.6e-18 65.7 2.3 3.4e-18 64.6 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EIM81199.1 - 9.9e-13 47.4 2.6 2.1e-12 46.3 1.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short PF00106.20 EIM81200.1 - 2.6e-10 40.4 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sec7 PF01369.15 EIM81201.1 - 1.4e-33 116.1 0.0 4.6e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EIM81201.1 - 9.3e-28 96.7 0.0 2.2e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIM81201.1 - 0.011 15.8 0.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 PH domain Glyoxalase PF00903.20 EIM81203.1 - 7e-21 74.5 0.1 9.6e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EIM81203.1 - 1.7e-15 57.5 0.0 2.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIM81203.1 - 7.4e-06 25.9 0.0 2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EIM81203.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain EAP30 PF04157.11 EIM81203.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family BUD22 PF09073.5 EIM81204.1 - 3.1 6.7 25.4 5.4 5.9 17.6 1.3 1 0 0 1 1 1 0 BUD22 Methyltransf_22 PF13383.1 EIM81205.1 - 3e-27 95.7 0.0 5.7e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.7 EIM81205.1 - 4.3e-07 30.0 0.0 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase FkbM domain Arylsulfotran_2 PF14269.1 EIM81206.1 - 1.4e-42 145.9 2.7 1.4e-42 145.9 1.9 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EIM81206.1 - 9e-13 47.5 3.0 1.4e-11 43.6 1.2 2.7 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) DUF2919 PF11143.3 EIM81206.1 - 0.12 12.2 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) BBP1_C PF15272.1 EIM81207.1 - 0.084 12.4 0.2 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Syntaxin-6_N PF09177.6 EIM81207.1 - 0.87 10.0 3.4 1.8 9.0 0.1 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DPBB_1 PF03330.13 EIM81208.1 - 0.00011 22.0 0.2 0.0003 20.7 0.2 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Rnk_N PF14760.1 EIM81209.1 - 0.013 15.5 0.4 7 6.8 0.0 2.6 2 0 0 2 2 2 0 Rnk N-terminus CPSF73-100_C PF11718.3 EIM81211.1 - 3e-58 196.7 0.1 5.1e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EIM81211.1 - 2.4e-34 117.9 0.0 5.7e-32 110.2 0.0 2.4 2 0 0 2 2 2 2 Beta-Casp domain Lactamase_B PF00753.22 EIM81211.1 - 3.5e-15 56.1 0.6 1.2e-14 54.4 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EIM81211.1 - 1.5e-10 40.7 0.1 3.4e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIM81211.1 - 3.7e-10 39.6 0.4 3.7e-10 39.6 0.3 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIM81211.1 - 4.5e-06 26.4 2.2 1.6e-05 24.6 0.1 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain CTD_bind PF04818.8 EIM81212.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRN7 PF11781.3 EIM81212.1 - 0.078 12.4 0.4 5.8 6.5 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_4 PF13894.1 EIM81212.1 - 0.094 13.0 1.1 2.6 8.5 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger BIR PF00653.16 EIM81212.1 - 0.12 12.7 0.3 11 6.5 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain PAT1 PF09770.4 EIM81212.1 - 1.3 7.1 13.7 2 6.5 9.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pro_isomerase PF00160.16 EIM81213.1 - 9.3e-46 155.8 0.8 1.1e-45 155.5 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IBR PF01485.16 EIM81214.1 - 4.7e-08 32.7 29.5 6.2e-06 25.9 4.5 3.4 3 0 0 3 3 3 3 IBR domain Abhydrolase_4 PF08386.5 EIM81215.1 - 2.2e-17 62.8 0.0 4.5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EIM81215.1 - 6.8e-11 42.1 0.0 2.2e-10 40.5 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM81215.1 - 4.3e-09 36.5 0.2 1.9e-08 34.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BCDHK_Adom3 PF10436.4 EIM81216.1 - 4.6e-41 140.0 0.0 1.3e-40 138.5 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIM81216.1 - 3.4e-14 52.5 0.0 8.4e-13 48.0 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIM81216.1 - 0.0042 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EIM81216.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.20 EIM81219.1 - 2.5e-54 184.1 0.0 3.8e-54 183.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81219.1 - 4.7e-23 81.5 0.0 6.9e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM81219.1 - 6.4e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM81219.1 - 0.00062 19.1 0.2 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EIM81219.1 - 0.016 14.8 0.2 0.051 13.1 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EIM81219.1 - 0.055 12.5 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LAG1-DNAbind PF09271.6 EIM81224.1 - 1.6e-33 116.1 0.0 2.8e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EIM81224.1 - 7.2e-23 81.0 0.0 7.9e-20 71.2 0.0 3.2 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain MOZ_SAS PF01853.13 EIM81225.1 - 2.9e-83 277.7 1.5 4e-83 277.2 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EIM81225.1 - 2.2e-18 65.7 0.0 4.3e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EIM81225.1 - 0.11 12.9 1.8 0.52 10.7 1.2 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type WD40 PF00400.27 EIM81226.1 - 4.8e-20 70.6 4.3 4.2e-10 39.1 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-GRF PF06839.7 EIM81226.1 - 2.7e-09 36.8 2.5 7.4e-09 35.3 1.7 1.8 1 0 0 1 1 1 1 GRF zinc finger C2 PF00168.25 EIM81226.1 - 1.8e-05 24.4 0.1 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.1 EIM81226.1 - 0.00031 20.7 1.5 0.0013 18.7 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EIM81226.1 - 0.0011 18.6 0.0 0.004 16.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.16 EIM81226.1 - 0.18 11.4 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Utp14 PF04615.8 EIM81226.1 - 8 4.4 16.3 12 3.9 11.3 1.1 1 0 0 1 1 1 0 Utp14 protein ERO1 PF04137.10 EIM81228.1 - 5.1e-119 397.4 0.0 6.6e-119 397.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KH_1 PF00013.24 EIM81229.1 - 1.4e-74 245.5 39.1 2.1e-13 49.6 0.4 12.6 11 1 0 11 11 11 10 KH domain KH_3 PF13014.1 EIM81229.1 - 9.6e-51 168.7 30.1 8.3e-09 34.9 0.1 11.6 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 EIM81229.1 - 2.3e-10 39.8 17.6 0.029 13.9 0.1 7.5 7 1 1 8 8 8 4 KH domain SLS PF14611.1 EIM81229.1 - 0.0061 16.0 15.6 0.72 9.2 0.0 7.2 7 3 1 9 9 9 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EIM81229.1 - 0.078 12.6 15.4 15 5.3 0.0 7.7 9 0 0 9 9 9 0 KH domain BMC PF00936.14 EIM81229.1 - 0.23 11.1 15.1 1.7 8.3 0.1 5.3 6 0 0 6 6 6 0 BMC domain DUF788 PF05620.6 EIM81230.1 - 5.2 6.8 13.5 11 5.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF788) RRM_1 PF00076.17 EIM81231.1 - 1.8e-09 37.0 0.0 0.00048 19.7 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EIM81231.1 - 3.2e-09 36.3 0.2 7e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 EIM81231.1 - 4e-06 26.6 0.0 1.5e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PP_M1 PF03012.9 EIM81231.1 - 0.35 10.1 4.7 0.046 13.0 0.4 1.6 2 0 0 2 2 2 0 Phosphoprotein Scs3p PF10261.4 EIM81232.1 - 5.5e-44 150.0 10.8 8.4e-43 146.1 7.5 2.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Exosortase_EpsH PF09721.5 EIM81232.1 - 0.57 9.3 11.4 0.074 12.2 0.6 2.2 2 0 0 2 2 2 0 Transmembrane exosortase (Exosortase_EpsH) WD40 PF00400.27 EIM81233.1 - 4.2e-16 58.1 8.7 3.5e-08 33.0 0.2 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat AAA_16 PF13191.1 EIM81233.1 - 6.4e-05 23.0 0.7 0.00026 21.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain C2 PF00168.25 EIM81233.1 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain NACHT PF05729.7 EIM81233.1 - 0.0012 18.5 0.1 0.0057 16.3 0.0 2.3 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EIM81233.1 - 0.028 13.2 0.0 0.059 12.2 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain PD40 PF07676.7 EIM81233.1 - 0.11 12.2 0.2 23 4.7 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ATP-sulfurylase PF01747.12 EIM81234.1 - 5.5e-87 290.5 0.4 7.6e-87 290.1 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EIM81234.1 - 1.6e-51 173.8 0.0 2.5e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EIM81234.1 - 4.1e-47 159.7 0.0 6.5e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIM81234.1 - 0.00088 19.1 0.2 0.0023 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EIM81234.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EIM81234.1 - 0.0058 16.2 0.2 0.067 12.8 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PsiA PF06952.6 EIM81234.1 - 0.024 13.6 0.0 3.4 6.6 0.0 3.0 3 0 0 3 3 3 0 PsiA protein AAA_29 PF13555.1 EIM81234.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EIM81234.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3 PF00933.16 EIM81235.1 - 2.9e-50 170.9 0.0 4.2e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM81235.1 - 6.8e-50 169.7 0.0 1.3e-49 168.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM81235.1 - 1.3e-25 89.1 0.2 3.2e-25 87.8 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PRTase_1 PF11202.3 EIM81235.1 - 0.068 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) 2-Hacid_dh_C PF02826.14 EIM81236.1 - 1.3e-45 154.7 0.0 1.8e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM81236.1 - 2.3e-19 69.1 0.0 2.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM81236.1 - 1.7e-05 24.7 0.0 5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ESAG1 PF03238.8 EIM81236.1 - 0.04 13.2 0.1 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 ESAG protein GFO_IDH_MocA PF01408.17 EIM81236.1 - 0.067 13.7 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 EIM81236.1 - 0.096 12.7 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.20 EIM81237.1 - 2.9e-24 84.7 0.1 8.5e-24 83.2 0.0 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 EIM81237.1 - 4.4e-08 33.1 1.1 7.9e-08 32.3 0.8 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM81237.1 - 3.3e-05 23.8 0.3 0.00011 22.2 0.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM81237.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM81237.1 - 0.096 12.4 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein GFO_IDH_MocA PF01408.17 EIM81239.1 - 2.1e-18 66.9 0.0 3.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM81239.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CDKN3 PF05706.7 EIM81240.1 - 2.7e-05 23.6 0.1 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.15 EIM81240.1 - 4.7e-05 22.9 0.2 9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIM81240.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIM81240.1 - 0.055 12.7 0.7 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Chitin_synth_2 PF03142.10 EIM81241.1 - 7.9e-247 819.8 0.0 1.1e-246 819.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM81241.1 - 7.5e-19 68.2 6.1 7.1e-18 65.0 4.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM81241.1 - 3.5e-16 59.7 0.0 1.3e-14 54.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIM81241.1 - 5.5e-06 25.7 0.1 0.00034 19.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 EIM81241.1 - 0.001 18.7 0.1 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIM81241.1 - 0.2 11.3 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF1080 PF06439.6 EIM81242.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) NmrA PF05368.8 EIM81244.1 - 1.2e-26 93.4 0.0 1.8e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM81244.1 - 8.2e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM81244.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase SBP_bac_11 PF13531.1 EIM81244.1 - 0.043 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein 3Beta_HSD PF01073.14 EIM81244.1 - 0.051 12.2 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Beta-lactamase PF00144.19 EIM81245.1 - 7.2e-37 127.1 2.3 1.1e-36 126.5 1.6 1.2 1 0 0 1 1 1 1 Beta-lactamase GFO_IDH_MocA PF01408.17 EIM81246.1 - 7.4e-17 61.9 0.0 1.2e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM81246.1 - 0.0089 16.4 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain zf-A20 PF01754.11 EIM81248.1 - 0.017 14.6 0.2 0.017 14.6 0.1 3.4 4 0 0 4 4 4 0 A20-like zinc finger SNARE PF05739.14 EIM81249.1 - 9.5e-18 63.6 0.2 3.1e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EIM81249.1 - 1.3e-08 34.9 7.9 2.2e-07 30.9 0.8 3.0 1 1 2 3 3 3 2 Syntaxin DUF1176 PF06674.6 EIM81249.1 - 0.022 13.9 0.4 0.03 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) V-SNARE PF05008.10 EIM81249.1 - 0.3 11.2 3.4 1.8 8.8 0.2 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3391 PF11871.3 EIM81249.1 - 0.57 10.3 4.6 4.5 7.4 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) ABC_membrane PF00664.18 EIM81250.1 - 1.1e-37 129.9 25.7 5.6e-19 68.6 6.5 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM81250.1 - 1.5e-35 122.4 0.1 3.5e-26 92.1 0.1 2.8 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EIM81250.1 - 2e-09 37.1 0.1 0.004 16.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EIM81250.1 - 1.9e-08 33.8 5.9 0.15 11.2 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EIM81250.1 - 1.4e-06 27.9 0.0 0.0049 16.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EIM81250.1 - 1.9e-06 27.3 0.2 0.052 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIM81250.1 - 7.6e-06 26.0 1.9 0.1 12.5 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EIM81250.1 - 1.1e-05 25.8 1.3 0.0035 17.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM81250.1 - 1.4e-05 25.1 3.0 0.039 13.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EIM81250.1 - 3.7e-05 22.7 0.0 0.022 13.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 EIM81250.1 - 0.00014 21.7 2.3 0.0044 16.8 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EIM81250.1 - 0.00057 19.8 0.5 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EIM81250.1 - 0.00059 19.5 0.8 0.79 9.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIM81250.1 - 0.00064 19.2 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain Adeno_IVa2 PF02456.10 EIM81250.1 - 0.00094 17.9 0.1 0.0063 15.2 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein Miro PF08477.8 EIM81250.1 - 0.0012 19.3 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EIM81250.1 - 0.0016 18.5 0.1 1.1 9.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIM81250.1 - 0.0027 18.5 1.0 4.9 7.9 0.2 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIM81250.1 - 0.0031 17.3 0.9 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EIM81250.1 - 0.0036 16.4 0.1 0.54 9.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 EIM81250.1 - 0.0038 16.4 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EIM81250.1 - 0.011 15.1 0.9 5.2 6.4 0.0 2.9 4 0 0 4 4 2 0 IstB-like ATP binding protein AAA PF00004.24 EIM81250.1 - 0.02 15.0 0.1 1.5 9.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIM81250.1 - 0.02 15.1 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIM81250.1 - 0.027 14.1 0.1 0.28 10.8 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 EIM81250.1 - 0.05 13.0 0.5 9.2 5.7 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EIM81250.1 - 0.072 12.8 0.2 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain TrwB_AAD_bind PF10412.4 EIM81250.1 - 0.076 11.6 1.4 2.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EIM81250.1 - 0.088 12.6 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EIM81250.1 - 0.11 12.2 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EIM81250.1 - 0.13 11.9 3.2 11 5.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 EIM81250.1 - 0.19 11.0 1.1 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.7 EIM81250.1 - 0.28 10.8 2.3 2.4 7.8 0.1 2.8 3 0 0 3 3 2 0 NACHT domain cobW PF02492.14 EIM81250.1 - 0.73 9.2 3.8 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2196 PF09962.4 EIM81250.1 - 0.93 9.3 2.9 15 5.4 0.0 3.0 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2196) Cpn60_TCP1 PF00118.19 EIM81251.1 - 9.5e-149 496.1 0.1 1.2e-148 495.7 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-LYAR PF08790.6 EIM81252.1 - 1.4e-14 53.4 2.4 2.9e-14 52.4 1.7 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DUF3133 PF11331.3 EIM81252.1 - 0.21 11.1 1.6 0.56 9.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Na_H_Exchanger PF00999.16 EIM81253.1 - 3.3e-52 177.2 22.8 3.8e-52 177.0 15.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_3 PF01494.14 EIM81254.1 - 3.6e-25 88.7 0.0 7.7e-25 87.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM81254.1 - 8.9e-06 24.8 0.3 0.02 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EIM81254.1 - 0.0078 15.0 0.0 0.044 12.6 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EIM81254.1 - 0.017 15.4 0.3 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM81254.1 - 0.019 15.0 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 EIM81254.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.9 EIM81254.1 - 0.041 13.7 0.1 0.34 10.7 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIM81254.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L11_N PF03946.9 EIM81255.1 - 7.6e-18 63.7 0.1 1.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIM81255.1 - 4.3e-14 52.4 0.4 7.2e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 EIM81255.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Pab87 octamerisation domain Cyclin PF08613.6 EIM81256.1 - 5.6e-27 94.9 0.3 5.6e-27 94.9 0.2 1.8 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIM81256.1 - 1.3e-06 27.9 0.1 2.1e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Methuselah_N PF06652.7 EIM81257.1 - 0.081 12.4 0.4 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Methuselah N-terminus NDUFA12 PF05071.11 EIM81257.1 - 0.17 12.3 6.9 0.2 12.1 4.8 1.1 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2500 PF10694.4 EIM81257.1 - 0.41 10.6 3.4 0.68 9.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Pkinase PF00069.20 EIM81258.1 - 3.9e-37 127.8 0.0 2.3e-35 122.0 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81258.1 - 4.2e-19 68.6 0.0 8.3e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81258.1 - 0.35 9.7 0.0 0.87 8.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Cwf_Cwc_15 PF04889.7 EIM81260.1 - 0.19 11.4 4.3 0.33 10.6 2.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Got1 PF04178.7 EIM81261.1 - 7.1e-21 74.5 13.3 8e-21 74.3 9.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EIM81261.1 - 0.096 11.6 10.4 0.099 11.5 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF308 PF03729.8 EIM81261.1 - 6.3 6.8 17.2 1.3 9.0 8.4 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) CAAD PF14159.1 EIM81261.1 - 9.7 5.9 10.9 8.8 6.0 2.0 2.6 1 1 2 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase F-box-like PF12937.2 EIM81262.1 - 1.6e-08 34.1 0.3 4.4e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81262.1 - 0.015 14.9 3.5 0.59 9.8 0.2 3.0 3 0 0 3 3 3 0 F-box domain BRO1 PF03097.13 EIM81263.1 - 9.8e-15 54.1 0.0 1.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Tmemb_40 PF10160.4 EIM81263.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein RPA_C PF08784.6 EIM81264.1 - 0.37 11.2 0.1 0.37 11.2 0.0 3.4 3 0 0 3 3 3 0 Replication protein A C terminal Paramyxo_ncap PF00973.14 EIM81264.1 - 6.1 5.4 20.5 8.5 4.9 13.6 1.7 1 1 0 1 1 1 0 Paramyxovirus nucleocapsid protein PI3_PI4_kinase PF00454.22 EIM81265.1 - 3.6e-37 128.0 0.0 5.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Voltage_CLC PF00654.15 EIM81266.1 - 1.4e-92 310.5 30.8 2e-92 309.9 21.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EIM81266.1 - 9.4e-12 44.5 0.6 0.00013 21.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF3612 PF12268.3 EIM81266.1 - 0.053 13.3 0.4 0.12 12.1 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3612) Autophagy_N PF03986.8 EIM81267.1 - 4.2e-46 156.3 0.1 9.1e-46 155.2 0.1 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EIM81267.1 - 2.5e-24 85.1 0.2 5e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EIM81267.1 - 3.8e-12 45.0 3.2 6.7e-12 44.2 2.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ERGIC_N PF13850.1 EIM81268.1 - 0.05 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CHZ PF09649.5 EIM81269.1 - 4.1e-07 29.1 0.1 4.1e-07 29.1 0.1 2.4 2 1 0 2 2 1 1 Histone chaperone domain CHZ FAM176 PF14851.1 EIM81269.1 - 0.031 13.9 8.8 0.017 14.8 5.0 1.4 1 1 0 1 1 1 0 FAM176 family CKAP2_C PF15297.1 EIM81269.1 - 0.17 10.6 2.1 0.2 10.4 1.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC27 PF09507.5 EIM81269.1 - 0.22 10.7 12.2 0.22 10.6 8.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Drc1-Sld2 PF11719.3 EIM81269.1 - 0.32 10.0 5.3 0.36 9.8 3.7 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Sigma70_ner PF04546.8 EIM81269.1 - 0.9 9.1 19.7 1.6 8.2 13.6 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EIM81269.1 - 1.5 7.2 16.5 1.6 7.0 11.4 1.2 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 EIM81269.1 - 2 8.5 26.8 0.068 13.3 12.3 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family RXT2_N PF08595.6 EIM81269.1 - 2.1 8.1 10.7 0.62 9.8 5.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal XAP5 PF04921.9 EIM81269.1 - 2.2 7.8 6.0 2.4 7.6 4.2 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.9 EIM81269.1 - 3.1 5.6 7.6 2.9 5.8 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.28 EIM81270.1 - 0.054 13.1 0.1 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 F-box domain DUF3756 PF12581.3 EIM81270.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) LRR_6 PF13516.1 EIM81270.1 - 0.62 10.3 3.8 25 5.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Methyltransf_31 PF13847.1 EIM81271.1 - 2.5e-13 49.8 0.2 3.7e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81271.1 - 9.6e-12 45.4 0.0 2.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIM81271.1 - 1.9e-11 43.6 0.0 3.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EIM81271.1 - 4.8e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM81271.1 - 1.3e-08 34.8 0.0 4.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EIM81271.1 - 1.3e-08 34.2 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EIM81271.1 - 3.1e-08 33.4 0.0 9.3e-08 31.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIM81271.1 - 2.3e-07 30.3 0.1 3.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EIM81271.1 - 3.2e-07 29.3 0.0 4.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EIM81271.1 - 1.1e-06 28.0 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EIM81271.1 - 2.7e-06 27.7 0.0 5.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM81271.1 - 3.9e-06 27.1 0.0 9.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIM81271.1 - 8.7e-05 22.5 0.0 0.00024 21.1 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EIM81271.1 - 0.00024 20.6 0.1 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EIM81271.1 - 0.00087 18.5 0.3 0.0032 16.6 0.2 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EIM81271.1 - 0.0031 16.6 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EIM81271.1 - 0.0038 16.6 0.1 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EIM81271.1 - 0.0046 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIM81271.1 - 0.023 14.2 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EIM81271.1 - 0.033 13.2 0.1 0.069 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 EIM81271.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 EIM81271.1 - 0.066 14.0 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2367 PF10164.4 EIM81272.1 - 6.6e-07 29.1 1.1 6.6e-07 29.1 0.7 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) zinc_ribbon_5 PF13719.1 EIM81272.1 - 0.049 13.2 0.2 0.084 12.4 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ATP1G1_PLM_MAT8 PF02038.11 EIM81272.1 - 0.5 9.4 2.2 0.86 8.6 1.5 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4510 PF14971.1 EIM81273.1 - 0.076 13.1 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) NOA36 PF06524.7 EIM81274.1 - 0.065 12.4 0.3 0.15 11.2 0.2 1.5 1 0 0 1 1 1 0 NOA36 protein bZIP_2 PF07716.10 EIM81275.1 - 4.1e-10 39.3 12.6 1e-09 38.0 3.4 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIM81275.1 - 4.2e-10 39.4 6.6 4.2e-10 39.4 4.6 2.2 1 1 1 2 2 2 1 bZIP transcription factor Mto2_bdg PF12808.2 EIM81275.1 - 0.017 15.2 1.3 0.017 15.2 0.9 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.13 EIM81275.1 - 0.054 13.4 0.6 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Fmp27_WPPW PF10359.4 EIM81275.1 - 0.099 11.0 4.5 0.14 10.5 3.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ax_dynein_light PF10211.4 EIM81275.1 - 0.19 11.5 6.3 0.32 10.8 4.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_Maf PF03131.12 EIM81275.1 - 0.22 11.8 9.7 0.14 12.4 5.2 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.10 EIM81275.1 - 0.41 10.1 4.5 6.4 6.3 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF605 PF04652.11 EIM81275.1 - 1.2 8.4 30.1 2.2 7.6 5.6 2.2 2 0 0 2 2 2 0 Vta1 like VanZ PF04892.7 EIM81276.1 - 0.00014 21.8 3.8 0.0004 20.3 2.6 1.8 1 1 0 1 1 1 1 VanZ like family MFS_2 PF13347.1 EIM81276.1 - 0.013 13.9 0.6 0.024 13.0 0.4 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein Acyl_transf_3 PF01757.17 EIM81276.1 - 0.034 12.9 3.9 0.047 12.5 2.7 1.1 1 0 0 1 1 1 0 Acyltransferase family TcpE PF12648.2 EIM81276.1 - 0.047 13.8 3.1 0.059 13.5 1.7 1.5 1 1 0 1 1 1 0 TcpE family Methyltransf_6 PF03737.10 EIM81277.1 - 3.5e-23 82.1 0.0 1e-22 80.6 0.0 1.7 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Peptidase_C14 PF00656.17 EIM81278.1 - 7.2e-18 65.1 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.13 EIM81279.1 - 2e-28 99.0 0.7 4.1e-28 97.9 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM81279.1 - 2.1e-08 33.9 10.6 3.8e-08 33.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EIM81280.1 - 1.9e-10 40.2 6.7 3.1e-10 39.5 4.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIM81280.1 - 0.57 9.5 4.7 1 8.7 3.2 1.3 1 0 0 1 1 1 0 PHD-finger PALP PF00291.20 EIM81281.1 - 1.2e-74 251.2 0.1 1.6e-74 250.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EIM81281.1 - 5.2e-45 150.9 0.0 7e-27 92.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase APG6 PF04111.7 EIM81284.1 - 4.7e-114 380.6 0.7 5.6e-114 380.4 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EIM81284.1 - 0.35 8.6 3.6 0.42 8.4 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EIM81284.1 - 1.5 8.4 12.7 2.9 7.5 8.8 1.4 1 0 0 1 1 1 0 Mnd1 family CPSF_A PF03178.10 EIM81285.1 - 2e-94 316.3 0.0 1.5e-93 313.4 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIM81285.1 - 5.6e-81 272.1 0.0 8.3e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Polysacc_synt PF01943.12 EIM81285.1 - 0.24 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IMS PF00817.15 EIM81286.1 - 1.3e-43 148.3 0.0 3.3e-43 147.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIM81286.1 - 2.9e-16 59.5 0.1 7.2e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIM81286.1 - 6.1e-07 29.1 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif GST_C PF00043.20 EIM81288.1 - 3.6e-11 42.9 0.0 5.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM81288.1 - 1.7e-08 34.5 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81288.1 - 3.5e-08 33.1 0.2 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM81288.1 - 3.8e-06 26.9 0.0 7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81288.1 - 7.8e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM81288.1 - 0.0053 17.2 0.3 0.0081 16.6 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3242 PF11586.3 EIM81288.1 - 0.12 11.9 0.5 5.6 6.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3242) MPC PF03650.8 EIM81289.1 - 9.4e-37 125.6 0.4 1.1e-36 125.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) RPA_interact_C PF14768.1 EIM81291.1 - 0.029 14.7 0.4 0.051 13.9 0.3 1.4 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Sugar_tr PF00083.19 EIM81292.1 - 6.6e-90 301.8 17.1 7.8e-90 301.5 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM81292.1 - 1.2e-19 70.2 22.4 1.2e-19 70.2 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1541 PF07563.6 EIM81293.1 - 0.035 13.7 0.5 0.082 12.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) peroxidase PF00141.18 EIM81294.1 - 7.7e-46 156.4 0.0 1.3e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase EcoRII-N PF09217.5 EIM81294.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal Stm1_N PF09598.5 EIM81296.1 - 0.075 13.7 3.0 0.15 12.8 2.0 1.6 1 0 0 1 1 1 0 Stm1 IBR PF01485.16 EIM81296.1 - 0.97 9.3 4.3 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 IBR domain SOBP PF15279.1 EIM81296.1 - 6 7.1 10.9 7.2 6.8 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Med3 PF11593.3 EIM81296.1 - 8.9 5.4 17.4 11 5.1 12.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aminotran_3 PF00202.16 EIM81297.1 - 2e-108 362.2 0.0 2.4e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIM81297.1 - 0.0037 16.2 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIM81297.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase zf-Apc11 PF12861.2 EIM81297.1 - 0.048 13.4 0.2 0.09 12.6 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EIM81298.1 - 1.6e-12 46.9 4.5 2.7e-12 46.2 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM81298.1 - 2.9e-07 30.5 0.9 5.7e-07 29.5 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIM81298.1 - 3.5e-05 23.5 1.6 6.5e-05 22.6 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIM81298.1 - 5.8e-05 22.7 2.7 9.8e-05 22.0 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM81298.1 - 0.00011 21.8 2.7 0.00018 21.0 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIM81298.1 - 0.00014 21.4 2.8 0.00023 20.6 2.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EIM81298.1 - 0.00031 20.6 4.1 0.00057 19.8 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM81298.1 - 0.0014 18.2 1.2 0.0025 17.4 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIM81298.1 - 0.0028 17.5 1.5 0.0074 16.2 1.1 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EIM81298.1 - 0.022 14.7 2.4 0.045 13.7 1.7 1.6 1 0 0 1 1 1 0 RING-variant domain Glyco_transf_18 PF15024.1 EIM81299.1 - 4.5e-10 38.5 0.0 7.3e-10 37.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glutaredoxin PF00462.19 EIM81300.1 - 4.2e-11 42.6 0.1 1.1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin HAD_2 PF13419.1 EIM81301.1 - 3.3e-15 56.7 0.0 4.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM81301.1 - 4.4e-06 27.2 0.0 2.1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIM81301.1 - 0.012 15.4 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM81301.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM81301.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3328 PF11807.3 EIM81302.1 - 0.025 14.2 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) adh_short PF00106.20 EIM81303.1 - 3.4e-06 27.0 1.7 0.0015 18.4 0.1 2.4 1 1 1 2 2 2 2 short chain dehydrogenase AMP-binding PF00501.23 EIM81306.1 - 8.6e-46 156.1 0.0 1.2e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM81306.1 - 0.00019 22.2 0.0 0.00068 20.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RHD3 PF05879.7 EIM81307.1 - 6e-247 821.3 0.5 1.3e-246 820.2 0.4 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIM81307.1 - 9.8e-08 31.3 0.9 2.3e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EIM81307.1 - 1.3e-05 25.1 0.0 7.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM81307.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EIM81307.1 - 2.5e-05 24.7 0.1 6.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EIM81307.1 - 0.0013 18.7 0.0 0.0043 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain LLC1 PF14945.1 EIM81307.1 - 0.019 15.3 0.7 0.04 14.2 0.5 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Septin PF00735.13 EIM81307.1 - 0.064 12.2 0.1 0.16 10.9 0.1 1.7 1 0 0 1 1 1 0 Septin BAR PF03114.13 EIM81308.1 - 1.8e-51 174.8 2.7 2.1e-51 174.6 1.9 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EIM81308.1 - 0.00049 19.5 3.2 0.27 10.5 0.1 2.1 2 0 0 2 2 2 2 Arfaptin-like domain DUF4164 PF13747.1 EIM81308.1 - 0.095 12.8 3.3 6 7.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Laminin_I PF06008.9 EIM81308.1 - 0.2 10.9 1.7 0.41 9.9 0.2 2.1 2 1 0 3 3 3 0 Laminin Domain I SYF2 PF08231.7 EIM81308.1 - 2.4 8.2 6.3 12 6.0 4.4 2.0 1 1 0 1 1 1 0 SYF2 splicing factor PBP1_TM PF14812.1 EIM81310.1 - 0.91 9.8 9.7 1.4 9.2 0.9 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 EIM81310.1 - 3.9 6.0 6.9 9.7 4.7 4.8 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Bd3614_N PF14442.1 EIM81310.1 - 7.5 6.5 10.9 1.6 8.6 0.0 3.4 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal NDUF_B12 PF08122.7 EIM81311.1 - 2.6e-17 62.2 2.4 3e-17 62.0 1.7 1.2 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I_N PF02919.10 EIM81312.1 - 1.1e-94 315.7 0.2 1.1e-94 315.7 0.1 3.6 3 2 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EIM81312.1 - 5.4e-89 297.3 4.7 1.7e-88 295.7 3.3 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EIM81312.1 - 7.9e-33 111.9 0.5 2.7e-32 110.2 0.4 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4582 PF15189.1 EIM81312.1 - 0.022 13.9 2.8 0.029 13.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) RolB_RolC PF02027.12 EIM81312.1 - 0.099 11.7 0.2 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 RolB/RolC glucosidase family CTP_transf_1 PF01148.15 EIM81313.1 - 6.7e-74 248.8 23.7 8.3e-74 248.4 16.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.20 EIM81314.1 - 2.7e-39 133.3 0.8 3.2e-39 133.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.15 EIM81315.1 - 1.5e-13 50.8 0.0 3.1e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM81315.1 - 8.1e-13 48.7 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81315.1 - 0.0034 17.1 0.0 0.031 14.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family CsbD PF05532.7 EIM81316.1 - 1e-14 53.9 12.8 1.5e-07 30.9 1.7 2.0 1 1 1 2 2 2 2 CsbD-like F-box PF00646.28 EIM81317.1 - 2.6e-07 30.1 0.3 9.4e-07 28.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM81317.1 - 2.5e-06 27.1 0.0 7.2e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Radical_SAM_N PF08497.5 EIM81317.1 - 0.15 10.9 0.1 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Glyco_hydro_2 PF00703.16 EIM81318.1 - 0.074 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Acyltransferase PF01553.16 EIM81319.1 - 4.3e-16 58.5 0.0 8e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase SPC22 PF04573.7 EIM81320.1 - 6.7e-41 139.4 0.0 7.5e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit LRR_4 PF12799.2 EIM81322.1 - 3.5e-58 192.4 49.1 7.1e-09 35.0 0.1 13.2 7 2 9 16 16 16 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM81322.1 - 3.4e-52 174.0 51.2 6.4e-15 54.6 0.7 10.4 6 2 5 11 11 11 8 Leucine rich repeat PP2C PF00481.16 EIM81322.1 - 4.9e-46 157.1 0.0 8.1e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EIM81322.1 - 1.3e-27 91.5 53.2 0.057 13.4 0.1 19.1 18 2 1 19 19 19 9 Leucine Rich Repeat Guanylate_cyc PF00211.15 EIM81322.1 - 1.7e-24 86.1 0.0 3.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EIM81322.1 - 9.3e-16 55.1 47.7 0.73 10.2 0.1 18.0 19 0 0 19 19 19 5 Leucine rich repeat LRR_6 PF13516.1 EIM81322.1 - 4.3e-13 47.8 43.1 0.96 9.7 0.1 15.3 15 2 2 17 17 17 5 Leucine Rich repeat LRR_5 PF13306.1 EIM81322.1 - 0.00045 19.9 0.9 3.6 7.2 0.1 3.9 4 1 0 4 4 4 2 Leucine rich repeats (6 copies) Mg_trans_NIPA PF05653.9 EIM81323.1 - 4.1e-80 268.9 27.0 5.5e-80 268.5 18.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIM81323.1 - 1.2e-06 28.6 9.1 1.2e-06 28.6 6.3 4.5 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EIM81323.1 - 0.00014 22.0 12.1 0.00014 22.0 8.4 3.6 2 2 1 3 3 3 1 Multidrug resistance efflux transporter Ank PF00023.25 EIM81325.1 - 1.1e-10 40.7 0.0 8.5e-06 25.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EIM81325.1 - 1.1e-10 41.3 2.0 1.5e-10 40.9 0.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 EIM81325.1 - 1.8e-10 40.9 0.1 3.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM81325.1 - 8.2e-09 35.4 0.2 5.8e-05 23.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM81325.1 - 8.5e-06 25.5 0.0 0.21 11.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EIM81325.1 - 0.0018 18.7 0.1 0.013 16.0 0.0 2.4 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ran_BP1 PF00638.13 EIM81326.1 - 3.9e-13 49.5 0.1 7.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EIM81326.1 - 3e-09 37.1 0.1 3e-09 37.1 0.1 6.3 7 3 0 7 7 7 1 NUP50 (Nucleoporin 50 kDa) RabGAP-TBC PF00566.13 EIM81327.1 - 8.1e-51 172.5 0.0 1.1e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.1 EIM81327.1 - 0.042 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 DZR PF12773.2 EIM81329.1 - 3.2 7.6 15.4 3.1 7.7 0.1 4.3 4 0 0 4 4 4 0 Double zinc ribbon Hist_deacetyl PF00850.14 EIM81330.1 - 4.1e-55 187.2 0.0 5.4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ILVD_EDD PF00920.16 EIM81331.1 - 6.4e-188 625.4 0.0 7.3e-188 625.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1793 PF08760.6 EIM81332.1 - 5.3e-58 195.6 1.5 1.1e-57 194.6 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) ETF_alpha PF00766.14 EIM81333.1 - 1.2e-34 117.8 1.1 2e-34 117.0 0.4 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EIM81333.1 - 6e-32 110.6 0.0 1.1e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPR_11 PF13414.1 EIM81334.1 - 4.4e-20 71.0 1.4 1.3e-10 40.7 0.0 3.7 3 1 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 EIM81334.1 - 2.3e-15 55.4 0.0 0.00015 21.2 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM81334.1 - 5.8e-14 50.8 6.1 0.00066 19.4 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM81334.1 - 1.6e-11 44.5 15.2 1.5e-09 38.2 0.0 5.0 4 2 2 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM81334.1 - 1.2e-10 41.1 1.7 0.00086 19.1 0.2 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM81334.1 - 4.3e-08 33.0 10.7 0.0024 18.3 0.0 6.5 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM81334.1 - 1.2e-07 31.3 0.3 0.076 13.2 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM81334.1 - 1.7e-07 30.4 0.1 0.95 9.4 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIM81334.1 - 1e-06 28.0 0.3 0.24 11.2 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM81334.1 - 1e-05 25.2 2.4 3.6 7.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM81334.1 - 4.6e-05 23.6 4.8 0.44 10.9 0.0 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIM81334.1 - 0.035 14.5 2.8 14 6.4 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM81334.1 - 0.036 13.9 2.5 3.7 7.4 0.0 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat Gemini_AL1 PF00799.15 EIM81334.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain TPR_20 PF14561.1 EIM81334.1 - 0.21 11.6 4.9 1 9.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat OPT PF03169.10 EIM81335.1 - 1.3e-129 433.5 36.7 1.5e-129 433.3 25.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_5 PF12695.2 EIM81337.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIM81337.1 - 0.0032 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIM81337.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81341.1 - 3e-07 30.3 0.0 7.9e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81341.1 - 7.6e-07 29.2 0.2 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIM81341.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EIM81341.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ThiF PF00899.16 EIM81342.1 - 7.1e-32 110.0 0.0 1.2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EIM81342.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EIM81342.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4449 PF14613.1 EIM81343.1 - 4.4e-16 59.2 0.0 4.4e-16 59.2 0.0 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) HisKA_3 PF07730.8 EIM81343.1 - 0.66 10.3 5.0 14 6.1 0.0 4.0 4 0 0 4 4 4 0 Histidine kinase GST_N_3 PF13417.1 EIM81344.1 - 1e-10 41.6 0.2 2.9e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81344.1 - 1.3e-08 34.6 0.5 3.5e-08 33.3 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIM81349.1 - 4.7e-10 39.5 0.2 1.3e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81349.1 - 1.2e-06 28.3 0.0 3.9e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAS_4 PF08448.5 EIM81349.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold GST_C_2 PF13410.1 EIM81349.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM81349.1 - 0.051 13.7 0.0 0.26 11.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81349.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GTP_CH_N PF12471.3 EIM81351.1 - 5.3e-85 283.9 0.0 7.4e-85 283.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EIM81351.1 - 3.3e-15 55.7 0.0 5.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Peptidase_A4 PF01828.12 EIM81352.1 - 1.9e-38 131.5 5.0 2.5e-38 131.2 3.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Tyrosinase PF00264.15 EIM81353.1 - 3.3e-53 181.1 3.2 3.3e-53 181.1 2.2 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Sugar_tr PF00083.19 EIM81354.1 - 2.1e-20 72.7 21.6 7.6e-17 61.0 1.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIM81354.1 - 2.4e-18 65.9 47.3 3.1e-12 45.8 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 EIM81354.1 - 0.077 13.1 0.2 0.25 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Polysacc_lyase PF14099.1 EIM81355.1 - 0.058 13.0 3.2 0.081 12.5 1.5 1.8 2 0 0 2 2 2 0 Polysaccharide lyase F-box-like PF12937.2 EIM81356.1 - 4.3e-05 23.1 0.2 0.00012 21.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 EIM81357.1 - 7.3e-08 32.3 0.0 2.5e-07 30.6 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Ribonuclease_3 PF00636.21 EIM81358.1 - 4.1e-44 149.6 0.0 8e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIM81358.1 - 7.2e-27 93.8 0.6 1.7e-09 37.7 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.24 EIM81358.1 - 2e-16 59.9 0.0 3.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM81358.1 - 1.5e-13 50.3 0.0 4.7e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EIM81358.1 - 5.4e-11 42.1 0.0 1.6e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EIM81358.1 - 6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AMP-binding PF00501.23 EIM81359.1 - 1.6e-33 115.7 0.0 3.4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM81359.1 - 2.7e-33 114.9 0.0 4.6e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM81359.1 - 3.3e-06 26.6 0.0 6.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIM81359.1 - 0.21 11.5 1.2 0.56 10.1 0.8 1.8 1 1 0 1 1 1 0 short chain dehydrogenase GST_N_3 PF13417.1 EIM81360.1 - 1.9e-11 44.0 0.3 5.1e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81360.1 - 1.6e-08 34.4 0.1 5.9e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81360.1 - 2.4e-05 24.2 0.2 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM81360.1 - 0.00016 21.4 0.1 0.00063 19.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 EIM81361.1 - 9.1e-18 64.8 0.3 1.7e-17 63.9 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM81361.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIM81361.1 - 0.05 12.6 0.0 3.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIM81361.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain GST_N_3 PF13417.1 EIM81362.1 - 2.5e-12 46.8 0.1 6.5e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81362.1 - 1.2e-09 37.9 0.3 8.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81362.1 - 0.00019 21.3 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.5 EIM81362.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold GST_C_2 PF13410.1 EIM81362.1 - 0.013 15.3 0.2 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM81362.1 - 0.066 13.3 0.0 0.26 11.5 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PAS PF00989.19 EIM81362.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PAS fold Cu-oxidase PF00394.17 EIM81363.1 - 2.4e-39 134.8 1.1 1.5e-38 132.2 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM81363.1 - 5.2e-32 110.2 1.6 2.3e-31 108.1 0.8 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM81363.1 - 1.6e-31 108.4 1.9 1.5e-26 92.3 0.0 3.6 3 1 0 3 3 3 3 Multicopper oxidase YrhK PF14145.1 EIM81365.1 - 4.8e-06 26.1 21.3 0.24 11.0 0.0 5.0 4 1 0 4 4 4 3 YrhK-like protein Lactamase_B_2 PF12706.2 EIM81366.1 - 3.6e-08 33.1 0.1 9.6e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EIM81366.1 - 3e-06 27.2 0.0 1.4e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EIM81366.1 - 0.029 14.0 1.2 0.13 11.8 0.8 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Endostatin PF06482.6 EIM81366.1 - 1.1 8.5 0.0 1.1 8.5 0.0 2.9 3 1 1 4 4 4 0 Collagenase NC10 and Endostatin F-box-like PF12937.2 EIM81367.1 - 0.00015 21.4 0.2 0.00067 19.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM81368.1 - 0.00029 20.4 0.1 0.00091 18.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM81369.1 - 6.2e-05 22.6 2.9 7.5e-05 22.3 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM81370.1 - 4.9e-05 22.9 0.2 0.00014 21.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Ribonuc_red_lgC PF02867.10 EIM81371.1 - 2e-212 706.5 0.0 2.7e-212 706.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIM81371.1 - 2.7e-24 84.7 0.1 1e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIM81371.1 - 1e-15 57.8 1.6 1.7e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain F-box-like PF12937.2 EIM81372.1 - 6.8e-06 25.7 0.1 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like GNAT_acetyltr_2 PF13718.1 EIM81373.1 - 3.4e-73 245.1 0.0 6e-73 244.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EIM81373.1 - 1.1e-65 220.6 0.0 4.4e-65 218.6 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EIM81373.1 - 1.7e-38 130.1 0.0 3.9e-38 129.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EIM81373.1 - 2.6e-32 110.9 0.7 7.8e-32 109.3 0.5 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EIM81373.1 - 0.0028 17.7 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain BTB PF00651.26 EIM81374.1 - 0.00097 19.1 0.1 0.0021 18.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain F-box-like PF12937.2 EIM81375.1 - 4.4e-07 29.5 0.3 2.1e-06 27.3 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM81376.1 - 2.1e-07 30.5 3.6 3.7e-07 29.7 0.0 2.8 3 0 0 3 3 3 1 F-box-like Methyltransf_23 PF13489.1 EIM81378.1 - 1.1e-14 54.4 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM81378.1 - 3.1e-12 46.3 0.0 3e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81378.1 - 4.4e-12 46.5 0.0 2.1e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM81378.1 - 5.9e-11 42.7 0.0 9.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81378.1 - 1.6e-08 34.9 0.0 6.8e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM81378.1 - 5.8e-06 25.7 0.0 8.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIM81378.1 - 1.6e-05 24.0 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EIM81378.1 - 1.7e-05 24.0 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EIM81378.1 - 2.8e-05 24.4 0.0 8.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM81378.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM81378.1 - 0.00028 20.0 0.0 0.00052 19.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIM81378.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 EIM81378.1 - 0.0025 17.1 0.0 0.013 14.7 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 EIM81378.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 EIM81378.1 - 0.026 13.7 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 EIM81378.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EIM81378.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 EIM81378.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.1 EIM81379.1 - 2.8e-15 56.3 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM81379.1 - 1.7e-13 50.3 0.0 1.6e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81379.1 - 1.3e-11 45.0 0.0 2.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM81379.1 - 6.1e-11 42.6 0.0 1.5e-10 41.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81379.1 - 1.2e-08 35.2 0.0 6.7e-08 32.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM81379.1 - 3.3e-06 27.1 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM81379.1 - 3.4e-05 22.9 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EIM81379.1 - 5.1e-05 22.9 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.9 EIM81379.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EIM81379.1 - 0.00022 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 EIM81379.1 - 0.00064 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EIM81379.1 - 0.00088 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EIM81379.1 - 0.0024 18.2 0.0 0.014 15.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EIM81379.1 - 0.0049 16.1 0.0 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.13 EIM81379.1 - 0.0059 15.8 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 EIM81379.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EIM81379.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.19 EIM81380.1 - 7.5e-35 120.3 23.3 1e-34 119.9 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM81380.1 - 2.2e-32 112.1 31.0 2.2e-32 112.1 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81381.1 - 4.6e-108 361.6 23.6 5.6e-108 361.4 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM81381.1 - 1.5e-21 76.5 39.7 1.8e-14 53.2 7.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ORMDL PF04061.9 EIM81381.1 - 0.028 13.9 2.8 0.067 12.7 1.9 1.6 1 0 0 1 1 1 0 ORMDL family DUF1700 PF08006.6 EIM81381.1 - 0.44 9.8 8.8 3.1 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) adh_short PF00106.20 EIM81382.1 - 4.4e-25 88.5 0.5 6e-25 88.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81382.1 - 6.7e-25 88.2 0.0 9.2e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81382.1 - 4.1e-14 52.6 0.1 6.6e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIM81382.1 - 0.0019 16.9 0.0 0.0037 15.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM81382.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PmrD PF11183.3 EIM81382.1 - 0.075 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD DUF3277 PF11681.3 EIM81382.1 - 0.086 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Transketolase_N PF00456.16 EIM81383.1 - 2.9e-122 407.6 0.0 4.9e-122 406.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIM81383.1 - 3.5e-41 140.6 0.0 5.7e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EIM81383.1 - 2.5e-08 33.1 0.0 0.0001 21.3 0.0 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EIM81383.1 - 3.6e-06 26.6 0.4 3.2e-05 23.5 0.3 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.15 EIM81383.1 - 0.00017 21.5 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EIM81383.1 - 0.0072 15.0 0.6 0.011 14.4 0.4 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MFS_1 PF07690.11 EIM81384.1 - 8.2e-35 120.1 32.4 8.2e-35 120.1 22.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81384.1 - 3.3e-32 111.6 22.6 5.9e-32 110.8 15.6 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter UPF0227 PF05728.7 EIM81384.1 - 0.17 11.6 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Complex1_LYR PF05347.10 EIM81385.1 - 0.01 15.6 0.2 0.01 15.6 0.1 3.3 3 0 0 3 3 3 1 Complex 1 protein (LYR family) L27_1 PF09058.5 EIM81385.1 - 0.034 14.0 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 L27_1 Bac_surface_Ag PF01103.18 EIM81386.1 - 4.4e-39 134.8 0.0 5.4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 EIM81386.1 - 0.0011 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat IBN_N PF03810.14 EIM81386.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain Ebp2 PF05890.7 EIM81388.1 - 4.9e-76 255.6 2.5 4.9e-76 255.6 1.7 1.7 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 PRP1_N PF06424.7 EIM81389.1 - 2.3e-47 160.6 2.5 2.3e-47 160.6 1.7 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EIM81389.1 - 3.8e-23 79.8 27.5 0.019 15.5 0.0 13.3 6 3 8 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 EIM81389.1 - 1.2e-17 64.0 13.9 5.1e-06 27.0 0.0 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIM81389.1 - 2.1e-12 47.2 13.0 0.029 14.7 0.0 8.6 5 4 4 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM81389.1 - 3.9e-05 23.2 0.2 0.36 10.4 0.1 5.9 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.1 EIM81389.1 - 0.00013 21.7 0.6 2.4 8.1 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM81389.1 - 0.00026 21.2 3.9 2 9.0 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Suf PF05843.9 EIM81389.1 - 0.01 15.6 0.0 8.8 5.9 0.0 4.1 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) DUF919 PF06034.6 EIM81391.1 - 0.029 14.0 0.8 0.048 13.2 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2413 PF10310.4 EIM81391.1 - 2.4 6.8 6.8 3 6.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SnAPC_2_like PF11035.3 EIM81391.1 - 4.3 6.7 8.8 0.94 8.8 0.4 2.0 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2-like PSS PF03034.10 EIM81393.1 - 1.4e-99 333.0 11.6 1.9e-99 332.5 8.0 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Actin PF00022.14 EIM81394.1 - 5.1e-78 262.2 0.0 6e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Actin NRDE PF05742.7 EIM81395.1 - 1.7e-35 122.7 0.0 4.8e-35 121.1 0.0 1.7 1 1 0 1 1 1 1 NRDE protein Zn_clus PF00172.13 EIM81397.1 - 1.5e-09 37.5 7.1 2.6e-09 36.8 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3365 PF11845.3 EIM81397.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) WD40_alt PF14077.1 EIM81397.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Dickkopf_N PF04706.7 EIM81397.1 - 0.74 10.0 10.3 1.1 9.4 7.2 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region IBN_N PF03810.14 EIM81399.1 - 3e-09 36.6 0.0 3.3e-06 26.8 0.0 3.1 2 1 0 2 2 2 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 EIM81399.1 - 0.00014 22.0 0.2 0.011 16.0 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats DUF2435 PF10363.4 EIM81399.1 - 0.027 14.3 0.2 0.2 11.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DUF4167 PF13763.1 EIM81399.1 - 0.21 11.6 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) HEAT_EZ PF13513.1 EIM81399.1 - 0.24 11.9 3.5 6.1 7.4 0.2 5.0 3 1 1 4 4 4 0 HEAT-like repeat F-box-like PF12937.2 EIM81401.1 - 2e-07 30.5 0.5 6e-07 29.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81401.1 - 0.00013 21.4 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain MscS_TM PF12794.2 EIM81402.1 - 0.022 13.3 0.1 0.022 13.3 0.1 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_S28 PF05577.7 EIM81403.1 - 5.3e-54 183.4 0.0 6.6e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Tombus_P33 PF08500.5 EIM81404.1 - 2.7 7.7 4.8 23 4.7 0.0 2.6 2 1 0 2 2 2 0 Tombusvirus p33 DUF659 PF04937.10 EIM81405.1 - 0.038 13.4 0.0 0.039 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) TAF PF02969.12 EIM81406.1 - 9.3e-27 92.7 0.3 5.6e-26 90.2 0.1 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EIM81406.1 - 1.3e-15 57.2 0.0 3.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 EIM81406.1 - 5.3e-05 23.2 0.2 0.00019 21.4 0.2 1.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF1918 PF08940.6 EIM81406.1 - 0.0018 17.5 0.0 0.006 15.8 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF1918) TFIID-31kDa PF02291.10 EIM81406.1 - 0.017 14.9 0.1 0.079 12.7 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EIM81406.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated Chitin_bind_4 PF00379.18 EIM81408.1 - 0.0099 16.1 0.2 0.03 14.5 0.1 1.9 1 1 0 1 1 1 1 Insect cuticle protein Melibiase PF02065.13 EIM81409.1 - 7.2e-16 57.8 0.3 3.8e-12 45.6 0.1 2.6 1 1 1 2 2 2 2 Melibiase Amidase PF01425.16 EIM81410.1 - 6.3e-88 295.5 0.1 8.6e-88 295.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Exc PF07825.6 EIM81410.1 - 0.22 11.3 0.5 0.85 9.4 0.1 2.0 1 1 1 2 2 2 0 Excisionase-like protein Kinesin PF00225.18 EIM81411.1 - 6.5e-92 307.7 0.0 1.3e-91 306.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain PfkB PF00294.19 EIM81412.1 - 8.8e-11 41.4 0.0 1.8e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Na_H_Exchanger PF00999.16 EIM81413.1 - 1.7e-58 198.0 23.5 2e-58 197.7 16.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Kin17_mid PF10357.4 EIM81414.1 - 4.7e-48 162.0 0.6 4.7e-48 162.0 0.4 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EIM81414.1 - 0.0008 19.5 4.6 0.002 18.2 3.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIM81414.1 - 0.019 15.0 3.8 0.029 14.4 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIM81414.1 - 0.021 14.9 3.8 0.021 14.9 2.6 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ecl1 PF12855.2 EIM81414.1 - 0.086 12.1 0.8 0.2 10.9 0.6 1.6 1 0 0 1 1 1 0 Life-span regulatory factor DUF3391 PF11871.3 EIM81414.1 - 0.71 10.0 5.9 0.15 12.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) OmpH PF03938.9 EIM81414.1 - 4.1 7.3 11.6 33 4.3 8.0 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) F-box PF00646.28 EIM81415.1 - 0.005 16.4 0.3 0.017 14.8 0.2 1.9 2 0 0 2 2 2 1 F-box domain ArfGap PF01412.13 EIM81415.1 - 0.06 13.1 2.6 0.087 12.6 0.6 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf BORA_N PF15280.1 EIM81415.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein aurora borealis N-terminus Tub_2 PF04525.7 EIM81416.1 - 2.6e-31 108.4 0.0 3.1e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 NmrA PF05368.8 EIM81417.1 - 4.7e-30 104.5 0.0 6.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM81417.1 - 2.4e-14 53.7 0.2 3.5e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM81417.1 - 2e-06 27.0 0.1 2.5e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EIM81417.1 - 0.00015 20.5 0.1 0.00022 20.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 EIM81417.1 - 0.00096 18.6 0.2 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EIM81417.1 - 0.0013 18.6 0.2 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EIM81417.1 - 0.027 13.9 0.0 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Amidase PF01425.16 EIM81418.1 - 1.1e-85 288.0 0.3 1.5e-85 287.7 0.2 1.1 1 0 0 1 1 1 1 Amidase DUF2793 PF10983.3 EIM81418.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) DUF2407_C PF13373.1 EIM81419.1 - 2.6e-22 79.2 6.3 5.8e-19 68.4 0.6 2.7 1 1 1 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.4 EIM81419.1 - 4.5e-14 52.4 0.0 8.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EIM81419.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 EIM81420.1 - 5.4e-07 29.0 0.0 1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM81420.1 - 8.7e-07 28.9 0.2 2.1e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM81420.1 - 0.0052 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EIM81420.1 - 0.1 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase F-box PF00646.28 EIM81423.1 - 0.0022 17.6 0.2 0.0064 16.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nop14 PF04147.7 EIM81423.1 - 0.032 12.1 2.5 0.044 11.7 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.2 EIM81423.1 - 0.04 13.6 0.2 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 F-box-like DUF4604 PF15377.1 EIM81423.1 - 0.084 13.0 10.8 0.13 12.4 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SURF2 PF05477.6 EIM81423.1 - 0.22 10.6 6.0 0.34 10.0 4.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) F-box PF00646.28 EIM81424.1 - 0.00011 21.7 0.5 0.00037 20.0 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM81424.1 - 0.045 13.4 0.2 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like BTB PF00651.26 EIM81425.1 - 6.3e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1932 PF09130.6 EIM81426.1 - 6.7e-15 54.5 0.0 2.4e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EIM81426.1 - 1.4e-07 31.5 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EIM81426.1 - 2.6e-05 23.6 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIM81426.1 - 0.00078 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EIM81426.1 - 0.006 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIM81426.1 - 0.036 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2884 PF11101.3 EIM81426.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Methyltransf_31 PF13847.1 EIM81428.1 - 9.9e-10 38.1 0.0 2.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81428.1 - 1.5e-07 31.7 0.0 7.8e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM81428.1 - 2.5e-07 31.0 0.0 5.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM81428.1 - 3.2e-05 23.7 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81428.1 - 6.4e-05 23.5 0.0 0.0018 18.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIM81428.1 - 0.00045 18.6 0.0 0.00061 18.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 EIM81428.1 - 0.035 13.3 0.0 0.077 12.2 0.0 1.5 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain F-box-like PF12937.2 EIM81430.1 - 0.016 14.9 0.1 0.069 12.8 0.0 2.2 2 0 0 2 2 2 0 F-box-like DUF3279 PF11682.3 EIM81430.1 - 0.26 10.8 5.5 0.7 9.4 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Asp PF00026.18 EIM81431.1 - 1.8e-48 165.4 20.4 4.4e-48 164.1 14.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM81431.1 - 4.5e-07 29.9 6.3 8.9e-06 25.7 3.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM81431.1 - 0.00021 21.7 6.8 0.0034 17.8 0.9 2.9 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EIM81431.1 - 0.021 14.3 0.2 0.067 12.7 0.1 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal SCIMP PF15050.1 EIM81434.1 - 0.26 11.1 3.1 6 6.7 0.0 2.9 2 1 0 2 2 2 0 SCIMP protein Yippee-Mis18 PF03226.9 EIM81434.1 - 0.62 10.1 5.1 2.2 8.3 0.2 3.4 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_5 PF13719.1 EIM81434.1 - 3.3 7.3 9.7 15 5.3 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM81434.1 - 3.9 7.2 10.1 14 5.4 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain HATPase_c PF02518.21 EIM81435.1 - 1.2e-50 169.8 0.1 1.7e-24 85.6 0.2 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM81435.1 - 8.2e-44 148.1 1.6 1.4e-24 86.2 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIM81435.1 - 6.2e-18 64.5 2.3 1.8e-10 40.6 0.1 2.9 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EIM81435.1 - 3.6e-06 26.9 0.0 0.052 13.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EIM81435.1 - 0.0003 20.5 0.0 0.0013 18.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.1 EIM81435.1 - 0.0017 18.1 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EIM81435.1 - 0.002 17.8 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2597 PF10772.4 EIM81435.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Glyco_hydro_35 PF01301.14 EIM81437.1 - 6.6e-76 255.6 0.1 1e-75 255.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM81437.1 - 1.6e-44 150.7 13.2 1.4e-22 80.0 0.3 4.0 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM81437.1 - 1.6e-39 135.1 6.0 2.7e-39 134.3 4.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM81437.1 - 1.8e-17 62.5 1.0 5.9e-17 60.8 0.1 2.4 4 0 0 4 4 4 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EIM81437.1 - 1.7e-05 24.1 0.3 0.00023 20.4 0.2 2.3 1 1 1 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.9 EIM81437.1 - 0.045 13.3 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase DUF718 PF05336.8 EIM81437.1 - 0.15 11.8 0.2 11 5.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF718) ABM PF03992.11 EIM81438.1 - 7.7e-08 32.2 0.1 1.2e-07 31.6 0.0 1.4 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase HapK PF11639.3 EIM81438.1 - 0.088 13.4 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 REDY-like protein HapK PP2C PF00481.16 EIM81439.1 - 2.3e-25 89.4 0.0 1.4e-21 77.0 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIM81439.1 - 8.5e-08 31.8 0.0 2.2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIM81439.1 - 0.00032 20.4 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Glyco_hydro_35 PF01301.14 EIM81441.1 - 2.2e-66 224.4 0.0 7.4e-66 222.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM81441.1 - 2.3e-44 150.1 1.4 1.3e-21 76.9 0.5 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM81441.1 - 3.2e-21 75.4 0.1 2.2e-20 72.8 0.1 2.0 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM81441.1 - 2.8e-13 49.0 0.0 7e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 EthD PF07110.6 EIM81442.1 - 9.4e-15 55.3 0.0 1.1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 EthD domain DUF2750 PF11042.3 EIM81442.1 - 0.011 15.7 0.1 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2750) WRKY PF03106.10 EIM81445.1 - 0.56 10.0 3.5 0.5 10.2 0.2 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain Epimerase PF01370.16 EIM81446.1 - 1.7e-16 60.3 0.0 7.2e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81446.1 - 1.3e-14 53.6 0.0 2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81446.1 - 6.3e-10 39.3 0.0 3.8e-09 36.8 0.0 2.2 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81446.1 - 3.6e-07 29.3 0.0 1.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIM81446.1 - 0.0025 16.7 0.0 0.012 14.5 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM81446.1 - 0.0035 17.2 0.0 0.0077 16.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM81446.1 - 0.0052 16.0 0.0 0.042 13.1 0.0 2.3 2 1 1 3 3 3 1 NmrA-like family RRM_6 PF14259.1 EIM81447.1 - 2.1e-09 37.2 0.1 2.6e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM81447.1 - 4.3e-08 32.6 0.1 0.00094 18.7 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM81447.1 - 7.4e-05 22.5 0.1 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EIM81448.1 - 3.1e-82 276.5 28.4 3.9e-82 276.2 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM81448.1 - 2.8e-43 147.9 49.0 6.2e-32 110.6 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EthD PF07110.6 EIM81449.1 - 8.2e-09 36.2 0.0 1e-08 35.9 0.0 1.1 1 0 0 1 1 1 1 EthD domain Glyco_hydro_35 PF01301.14 EIM81450.1 - 3.3e-74 250.0 0.0 4.8e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM81450.1 - 6e-46 155.2 11.4 1.4e-22 80.0 0.1 4.2 4 0 0 4 4 4 3 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM81450.1 - 1.9e-37 128.3 5.0 3.9e-37 127.3 3.4 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM81450.1 - 6.2e-19 67.1 0.3 8.9e-18 63.4 0.1 2.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 EIM81450.1 - 0.033 13.7 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase Sec23_BS PF08033.7 EIM81450.1 - 0.042 14.3 0.4 1 9.8 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain DUF718 PF05336.8 EIM81450.1 - 0.09 12.5 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF718) zf-MYND PF01753.13 EIM81451.1 - 1.1e-05 25.1 8.2 1.1e-05 25.1 5.7 1.7 2 0 0 2 2 2 1 MYND finger Abhydrolase_3 PF07859.8 EIM81452.1 - 1.5e-62 210.9 0.0 1.8e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM81452.1 - 1e-08 34.3 0.4 2.3e-08 33.2 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EIM81452.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81452.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EIM81452.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EIM81452.1 - 0.0032 16.3 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EIM81452.1 - 0.0044 16.2 0.0 0.045 12.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EIM81452.1 - 0.0051 15.4 0.0 0.0065 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 EIM81452.1 - 0.027 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1187 PF06688.6 EIM81452.1 - 0.14 12.3 0.4 0.31 11.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) FAD_binding_4 PF01565.18 EIM81453.1 - 1.1e-16 60.5 0.3 2.1e-16 59.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM81453.1 - 1.3e-08 34.5 0.3 4.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like P53_C PF11619.3 EIM81453.1 - 0.03 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Glyco_hydro_43 PF04616.9 EIM81457.1 - 1.7e-11 43.7 6.9 3.5e-11 42.7 4.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pyridox_oxidase PF01243.15 EIM81457.1 - 0.1 12.6 0.2 0.87 9.6 0.0 2.5 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase DUF3328 PF11807.3 EIM81461.1 - 5.7e-14 52.3 0.1 8.5e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 EIM81462.1 - 0.00022 21.0 0.0 0.00088 19.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EIM81464.1 - 5.2e-22 78.6 0.7 7.4e-22 78.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Staygreen PF12638.2 EIM81464.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Staygreen protein Acetyltransf_1 PF00583.19 EIM81465.1 - 0.00083 19.3 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM81465.1 - 0.0074 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM81465.1 - 0.011 15.6 0.1 0.029 14.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM81465.1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM81465.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Hist_deacetyl PF00850.14 EIM81466.1 - 3.1e-59 200.8 0.0 4e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain XPG_N PF00752.12 EIM81467.1 - 2e-33 114.6 0.0 4.9e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIM81467.1 - 8.1e-29 99.5 0.0 2.7e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EIM81467.1 - 8.5e-08 32.3 0.1 2.2e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Abhydrolase_3 PF07859.8 EIM81468.1 - 7.2e-28 97.6 0.0 1.7e-27 96.4 0.0 1.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM81468.1 - 0.00017 20.3 0.0 0.029 12.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Thioesterase PF00975.15 EIM81468.1 - 0.068 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain 4HBT_3 PF13622.1 EIM81469.1 - 1.6e-35 123.0 8.9 2e-35 122.7 6.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EIM81469.1 - 0.021 14.9 0.5 1.9 8.6 0.1 3.3 3 1 0 3 3 3 0 Thioesterase superfamily p450 PF00067.17 EIM81470.1 - 9.9e-63 212.2 0.0 1.2e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM81471.1 - 2.5e-64 217.5 0.0 2.8e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.18 EIM81472.1 - 2e-10 40.0 5.7 0.00011 21.9 0.4 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIM81472.1 - 0.00015 21.3 4.7 0.069 12.8 0.2 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIM81472.1 - 0.0058 16.3 0.4 0.45 10.2 0.0 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIM81472.1 - 0.0065 16.1 7.4 0.28 10.9 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-BED PF02892.10 EIM81472.1 - 0.012 15.3 1.0 0.55 10.0 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger Rpr2 PF04032.11 EIM81472.1 - 0.042 13.7 2.1 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC_2 PF13696.1 EIM81472.1 - 1.2 8.6 5.8 21 4.7 1.4 2.9 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM81472.1 - 4.2 6.9 8.7 3.7 7.1 1.8 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Gelsolin PF00626.17 EIM81473.1 - 5.3e-34 115.7 0.0 3.4e-15 55.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Methyltransf_33 PF10017.4 EIM81474.1 - 6.4e-32 110.1 0.1 1.4e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EIM81474.1 - 5e-18 65.3 1.6 1.5e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIM81474.1 - 4.1e-07 30.3 0.1 8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 DinB superfamily DEAD PF00270.24 EIM81475.1 - 1e-17 64.1 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM81475.1 - 3.1e-12 46.1 0.0 7.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM81475.1 - 0.0013 17.5 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HHH_5 PF14520.1 EIM81476.1 - 0.036 14.2 0.3 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3915 PF13054.1 EIM81477.1 - 2.7 7.9 5.4 9.6 6.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF4484 PF14831.1 EIM81477.1 - 7.2 6.6 8.0 0.18 11.8 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF3415 PF11895.3 EIM81478.1 - 6.9e-28 96.3 3.2 2.1e-27 94.8 2.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 EIM81478.1 - 7.1e-24 84.5 0.6 1.2e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 Peroxidase NAD_binding_1 PF00175.16 EIM81479.1 - 0.00029 21.3 0.0 0.00088 19.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pyridox_oxidase PF01243.15 EIM81479.1 - 0.017 15.1 0.0 6.3 6.8 0.0 2.9 3 1 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.7 EIM81479.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Glyco_hydro_92 PF07971.7 EIM81480.1 - 4.8e-146 487.3 0.1 4.8e-146 487.3 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 F-box-like PF12937.2 EIM81481.1 - 2e-08 33.8 0.0 8.3e-08 31.8 0.0 2.2 1 1 0 1 1 1 1 F-box-like zf-C2H2 PF00096.21 EIM81483.1 - 2e-12 46.6 8.4 6.6e-06 26.1 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM81483.1 - 8e-11 41.6 16.6 2.4e-08 33.8 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM81483.1 - 2.4e-09 36.8 8.4 0.00014 21.8 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.13 EIM81483.1 - 0.0017 18.6 0.7 0.0019 18.5 0.5 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger RPAP2_Rtr1 PF04181.8 EIM81483.1 - 0.02 14.9 0.2 2.6 8.2 0.0 2.0 1 1 1 2 2 2 0 Rtr1/RPAP2 family Ogr_Delta PF04606.7 EIM81483.1 - 0.13 11.9 0.2 6.4 6.5 0.1 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 EIM81483.1 - 0.99 9.1 3.9 21 4.9 0.4 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EIM81483.1 - 6.1 6.9 6.1 7.8 6.5 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.2 EIM81485.1 - 2.5e-10 39.9 0.0 1.1e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81485.1 - 0.33 10.6 6.1 4.4 7.0 0.1 3.5 3 0 0 3 3 3 0 F-box domain Terpene_synth_C PF03936.11 EIM81486.1 - 1.5e-16 60.4 0.1 1.9e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EIM81486.1 - 0.0033 16.1 0.1 0.0057 15.3 0.1 1.3 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF3415 PF11895.3 EIM81487.1 - 7.4e-31 105.8 1.6 1.9e-30 104.5 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 EIM81487.1 - 4.6e-24 85.1 0.0 8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase WD40 PF00400.27 EIM81489.1 - 3e-17 61.7 4.6 2.4e-05 24.0 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-DHHC PF01529.15 EIM81490.1 - 1.5e-36 125.3 0.6 9.3e-36 122.8 0.4 2.2 1 1 0 1 1 1 1 DHHC palmitoyltransferase FAM176 PF14851.1 EIM81490.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Avl9 PF09794.4 EIM81491.1 - 1.6e-130 434.9 0.0 2.1e-130 434.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EIM81491.1 - 2.1e-06 27.2 7.4 1.7e-05 24.2 0.2 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EIM81491.1 - 5.2e-06 26.1 0.0 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis F-box-like PF12937.2 EIM81492.1 - 5e-06 26.1 3.4 1.4e-05 24.6 2.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM81492.1 - 0.012 15.1 0.1 0.66 9.6 0.0 3.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) TPR_12 PF13424.1 EIM81493.1 - 3.4e-12 46.1 4.0 0.014 15.3 0.0 4.3 1 1 2 4 4 4 4 Tetratricopeptide repeat AAA_22 PF13401.1 EIM81493.1 - 7.8e-08 32.5 0.0 3.2e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain SNAP PF14938.1 EIM81493.1 - 5.3e-07 29.0 0.5 0.00084 18.5 0.2 2.8 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP NB-ARC PF00931.17 EIM81493.1 - 4.6e-06 25.6 0.0 9.9e-06 24.6 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EIM81493.1 - 9.7e-05 22.0 0.1 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM81493.1 - 0.0024 17.9 2.7 0.15 12.0 0.0 3.8 3 2 2 5 5 5 1 AAA ATPase domain ABC_tran PF00005.22 EIM81493.1 - 0.003 17.8 0.0 0.0063 16.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TPR_11 PF13414.1 EIM81493.1 - 0.012 15.2 1.7 0.072 12.7 0.1 3.1 3 1 0 3 3 3 0 TPR repeat IstB_IS21 PF01695.12 EIM81493.1 - 0.048 13.0 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 EIM81493.1 - 0.099 12.2 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rabaptin PF03528.10 EIM81493.1 - 0.19 11.6 0.8 9.5 6.1 0.1 3.0 3 0 0 3 3 3 0 Rabaptin YjeF_N PF03853.10 EIM81494.1 - 3.6e-38 130.8 0.0 4.5e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Dioxygenase_C PF00775.16 EIM81495.1 - 2e-11 43.4 0.1 1.7e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 Dioxygenase F-box PF00646.28 EIM81496.1 - 0.0023 17.5 0.4 0.0048 16.5 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM81496.1 - 0.0038 16.9 0.3 0.011 15.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like DUF4014 PF13198.1 EIM81496.1 - 0.36 11.2 2.0 0.4 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) zf-RING_2 PF13639.1 EIM81497.1 - 4.8e-13 48.6 10.2 7.5e-09 35.2 3.0 3.1 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EIM81497.1 - 9.1e-08 31.6 1.7 5.3e-05 22.7 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM81497.1 - 2e-07 31.0 2.2 1.3e-05 25.2 0.4 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIM81497.1 - 1.3e-06 27.9 3.1 0.00039 20.0 0.4 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM81497.1 - 0.00016 21.5 2.3 0.00016 21.5 1.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM81497.1 - 0.0012 18.6 3.9 0.0028 17.4 0.1 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EIM81497.1 - 0.0018 17.8 0.9 0.0018 17.8 0.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EIM81497.1 - 0.063 13.3 0.8 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EIM81497.1 - 0.22 11.4 3.8 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 FANCL C-terminal domain PHD PF00628.24 EIM81497.1 - 8.1 6.2 5.7 15 5.4 0.9 2.6 2 0 0 2 2 2 0 PHD-finger PhyH PF05721.8 EIM81498.1 - 6.7e-13 49.1 0.0 1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Tyrosinase PF00264.15 EIM81499.1 - 5.9e-39 134.5 0.7 7.4e-39 134.1 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.17 EIM81500.1 - 3.5e-73 246.6 0.0 4.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF760 PF05542.6 EIM81500.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Tyrosinase PF00264.15 EIM81501.1 - 3.7e-40 138.4 2.1 4.7e-40 138.1 1.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1155 PF06633.6 EIM81502.1 - 0.1 11.8 0.3 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) zf-MYND PF01753.13 EIM81504.1 - 5.6e-11 42.1 7.0 2.2e-10 40.2 4.9 2.0 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM81504.1 - 1.9e-05 24.4 1.3 6.1e-05 22.7 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 adh_short PF00106.20 EIM81505.1 - 7.7e-16 58.4 0.2 1.1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM81505.1 - 1.9e-08 34.2 0.1 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Lamprin PF06403.6 EIM81505.1 - 0.043 13.5 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Lamprin Polysacc_synt_2 PF02719.10 EIM81505.1 - 0.071 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Malate_DH PF12434.3 EIM81506.1 - 0.0055 16.3 1.8 0.01 15.5 1.3 1.5 1 0 0 1 1 1 1 Malate dehydrogenase enzyme Mucin PF01456.12 EIM81507.1 - 0.22 11.2 4.6 0.4 10.4 3.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop PF01798.13 EIM81508.1 - 6e-59 197.6 0.0 1e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIM81508.1 - 1.4e-26 92.0 0.1 2.4e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIM81508.1 - 1.6e-23 82.6 0.2 1.6e-23 82.6 0.1 2.3 2 1 0 2 2 2 1 NOP5NT (NUC127) domain CoatB PF10389.4 EIM81508.1 - 0.094 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B Pro-kuma_activ PF09286.6 EIM81511.1 - 3.8e-31 108.0 0.0 6.9e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM81511.1 - 3.3e-06 26.4 0.0 6.2e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family DUF3085 PF11284.3 EIM81511.1 - 0.055 13.6 0.1 0.44 10.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3085) CRAL_TRIO_2 PF13716.1 EIM81513.1 - 1.2e-32 112.9 0.1 2.7e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EIM81513.1 - 3.2e-31 108.0 0.0 4.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EIM81513.1 - 3.6e-05 23.2 0.4 0.00037 20.0 0.2 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain Na_H_Exchanger PF00999.16 EIM81514.1 - 6.6e-62 209.2 44.3 9.5e-62 208.6 30.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ThuA PF06283.6 EIM81515.1 - 9.4e-58 195.4 0.3 1.1e-57 195.2 0.2 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1270 PF06900.6 EIM81516.1 - 3 8.0 6.5 0.28 11.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DUF3415 PF11895.3 EIM81517.1 - 7.7e-31 105.7 2.9 1.1e-30 105.3 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 EIM81517.1 - 4.7e-27 94.9 0.0 9.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Peroxidase bZIP_1 PF00170.16 EIM81518.1 - 1.7e-08 34.2 8.7 2.9e-08 33.5 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIM81518.1 - 4.6e-06 26.3 10.5 4.6e-06 26.3 7.3 1.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIM81518.1 - 0.011 15.9 5.4 0.011 15.9 3.7 1.6 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF1635 PF07795.6 EIM81518.1 - 0.26 10.6 2.0 0.37 10.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Gtr1_RagA PF04670.7 EIM81519.1 - 3.2e-44 150.7 0.0 4.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM81519.1 - 0.0051 17.3 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Glyco_hydro_28 PF00295.12 EIM81520.1 - 7.6e-51 172.9 17.3 9.8e-51 172.6 12.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TerD PF02342.13 EIM81520.1 - 0.028 13.7 0.8 0.042 13.1 0.6 1.4 1 0 0 1 1 1 0 TerD domain End_N_terminal PF12218.3 EIM81520.1 - 0.044 13.2 0.2 0.83 9.1 0.0 2.8 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.14 EIM81521.1 - 0.0076 14.8 0.1 0.008 14.7 0.1 1.1 1 0 0 1 1 1 1 Pectinesterase 7TM_GPCR_Sru PF10322.4 EIM81521.1 - 0.09 11.8 0.2 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Pectinesterase PF01095.14 EIM81522.1 - 2.8e-36 124.5 0.3 3.4e-36 124.3 0.2 1.0 1 0 0 1 1 1 1 Pectinesterase GDA1_CD39 PF01150.12 EIM81523.1 - 9.9e-89 297.7 0.0 1.3e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GMC_oxred_C PF05199.8 EIM81524.1 - 6.7e-14 52.3 0.0 1.8e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIM81524.1 - 5e-07 29.1 0.0 1.9e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EIM81524.1 - 0.00049 19.1 0.1 0.0013 17.6 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM81524.1 - 0.0081 16.1 0.2 0.03 14.3 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GDI PF00996.13 EIM81524.1 - 0.032 12.5 0.0 0.049 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 EIM81524.1 - 0.086 11.9 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EIM81524.1 - 0.11 11.3 0.2 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Methyltransf_16 PF10294.4 EIM81525.1 - 3e-17 62.6 0.0 4.2e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM81525.1 - 0.0027 18.2 0.0 0.0044 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM81525.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EIM81525.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EIM81525.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.10 EIM81525.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cut8_N PF14482.1 EIM81528.1 - 0.69 9.9 4.8 0.73 9.8 1.4 2.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain DUF2422 PF10337.4 EIM81529.1 - 1.7e-88 297.4 0.0 1.7e-88 297.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIM81529.1 - 7.4e-32 110.8 0.0 8.7e-30 104.0 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIM81529.1 - 7.5e-10 38.8 12.4 7.5e-10 38.8 8.6 3.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like PRTP PF01366.13 EIM81529.1 - 0.17 9.8 0.2 0.31 8.9 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein WLM PF08325.5 EIM81531.1 - 4.4e-49 166.8 0.0 7.6e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EIM81531.1 - 1.5e-06 27.1 1.6 1.5e-06 27.1 1.1 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.2 EIM81531.1 - 0.0018 18.0 7.7 0.0037 17.0 5.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon DUF605 PF04652.11 EIM81531.1 - 0.013 14.8 7.2 0.017 14.5 5.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF45 PF01863.12 EIM81531.1 - 0.022 14.5 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 SprT-like PF10263.4 EIM81531.1 - 0.17 11.5 0.4 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 SprT-like family SPRY PF00622.23 EIM81532.1 - 4.1e-13 49.4 0.0 8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF1227 PF06777.6 EIM81532.1 - 0.095 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) Pkinase PF00069.20 EIM81533.1 - 2.4e-12 46.5 0.0 3.2e-11 42.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81533.1 - 0.0023 17.0 0.0 0.0062 15.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase GST_N_3 PF13417.1 EIM81534.1 - 2.8e-13 49.8 0.0 9.3e-13 48.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81534.1 - 8.2e-09 35.3 0.0 2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81534.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM81534.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM81535.1 - 3.4e-12 46.3 0.1 9.6e-12 44.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81535.1 - 1.2e-08 34.7 0.2 1.3e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM81535.1 - 0.0082 16.2 0.0 0.13 12.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81535.1 - 0.044 13.6 0.0 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM81535.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.18 EIM81536.1 - 2.6e-22 78.7 0.5 9.2e-22 77.0 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EIM81536.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like NMO PF03060.10 EIM81537.1 - 3.6e-63 213.7 0.0 4.7e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIM81537.1 - 4.6e-09 35.6 0.0 9.6e-05 21.4 0.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIM81537.1 - 0.0033 16.3 0.3 0.0048 15.7 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.12 EIM81537.1 - 0.013 14.6 0.1 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Glu_synthase PF01645.12 EIM81537.1 - 0.017 14.0 0.1 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 EIM81537.1 - 0.03 13.3 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EIM81537.1 - 0.085 12.1 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 EIM81537.1 - 0.097 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.7 EIM81537.1 - 0.16 10.9 0.1 0.39 9.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF561) Abhydrolase_6 PF12697.2 EIM81539.1 - 4e-17 62.8 1.0 7.2e-17 62.0 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81539.1 - 1.9e-06 27.6 0.0 5.9e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM81539.1 - 0.016 14.7 0.0 0.057 12.9 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM81539.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N_3 PF13417.1 EIM81540.1 - 1.9e-13 50.4 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81540.1 - 1.2e-08 34.8 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM81540.1 - 0.0048 17.0 0.0 0.02 15.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LRR_8 PF13855.1 EIM81541.1 - 0.0034 17.1 1.6 0.0039 16.9 0.1 1.9 2 0 0 2 2 2 1 Leucine rich repeat AF-4 PF05110.8 EIM81541.1 - 0.038 11.8 0.3 0.051 11.4 0.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRR_4 PF12799.2 EIM81541.1 - 0.094 12.3 0.4 0.28 10.8 0.3 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Myf5 PF12232.3 EIM81542.1 - 2.4 8.8 12.9 0.29 11.7 5.2 2.3 2 0 0 2 2 2 0 Myogenic determination factor 5 Pkinase PF00069.20 EIM81543.1 - 3e-53 180.6 0.0 3.3e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81543.1 - 1.2e-27 96.6 0.1 1.4e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81543.1 - 2.9e-07 29.7 0.1 4.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIM81543.1 - 0.00032 20.1 1.0 0.0022 17.3 0.3 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EIM81543.1 - 0.0054 16.4 0.0 0.47 10.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIM81543.1 - 0.022 13.8 0.2 0.036 13.1 0.1 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.1 EIM81544.1 - 4.8e-23 82.2 0.0 7.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM81544.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Prenyltrans_2 PF13249.1 EIM81544.1 - 0.11 12.8 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Prenyltransferase-like Prenyltrans PF00432.16 EIM81544.1 - 0.14 11.7 0.8 0.49 10.0 0.6 2.0 1 1 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat adh_short PF00106.20 EIM81545.1 - 1.3e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81545.1 - 3.4e-05 23.7 0.0 0.00012 21.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM81545.1 - 0.0037 17.2 0.0 0.0068 16.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM81545.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 KR domain Abhydrolase_6 PF12697.2 EIM81546.1 - 1.9e-15 57.4 0.8 2.9e-15 56.7 0.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81546.1 - 8.8e-05 22.2 0.0 0.00014 21.6 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EIM81546.1 - 0.052 12.1 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EIM81547.1 - 1.5e-14 54.4 0.2 2.2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81547.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.7 EIM81547.1 - 0.00055 18.9 0.0 0.0008 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 EIM81547.1 - 0.0088 15.6 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF3435 PF11917.3 EIM81547.1 - 0.04 12.6 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_transf_28 PF03033.15 EIM81548.1 - 9.2e-26 90.2 0.0 1.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EIM81548.1 - 1e-05 24.3 0.0 2.3e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 EIM81548.1 - 4.6e-05 23.5 0.0 0.00029 20.9 0.0 2.3 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EIM81548.1 - 0.0055 16.2 0.0 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 GRAM domain F-box-like PF12937.2 EIM81549.1 - 5.3e-12 45.2 0.2 1.4e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM81550.1 - 2.3e-07 30.3 0.1 1.3e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 F-box-like DUF4409 PF14365.1 EIM81553.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4409) PIF1 PF05970.9 EIM81554.1 - 7.4e-08 31.7 0.0 2.6e-05 23.3 0.0 2.5 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIM81557.1 - 1.1e-09 38.3 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ycf1 PF05758.7 EIM81560.1 - 3.5 5.2 7.9 6.7 4.2 5.5 1.4 1 0 0 1 1 1 0 Ycf1 WD40 PF00400.27 EIM81563.1 - 7.1e-115 371.2 52.5 3.1e-12 45.8 0.2 14.8 15 0 0 15 15 14 14 WD domain, G-beta repeat DUF2235 PF09994.4 EIM81563.1 - 2.6e-45 154.9 0.3 4.7e-45 154.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Nup160 PF11715.3 EIM81563.1 - 4.4e-11 41.6 9.9 0.35 8.9 0.0 8.1 4 3 4 8 8 8 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIM81563.1 - 1.2e-07 31.4 1.8 0.012 15.0 0.1 4.4 2 2 2 4 4 4 3 PQQ-like domain Cytochrom_D1 PF02239.11 EIM81563.1 - 1.2e-07 30.3 0.0 0.21 9.8 0.0 3.9 3 1 1 4 4 4 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIM81563.1 - 1.6e-06 27.1 12.3 1.1 7.8 0.1 6.8 4 2 2 6 6 6 4 Nup133 N terminal like Hira PF07569.6 EIM81563.1 - 0.0023 17.1 0.0 5.8 6.0 0.0 5.3 5 2 2 7 7 7 1 TUP1-like enhancer of split PQQ_3 PF13570.1 EIM81563.1 - 0.01 16.0 0.8 15 5.9 0.0 4.9 4 0 0 4 4 4 0 PQQ-like domain DUF1797 PF08796.5 EIM81563.1 - 0.12 12.2 0.0 12 5.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) RHD3 PF05879.7 EIM81563.1 - 0.15 9.9 0.0 0.23 9.3 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) PD40 PF07676.7 EIM81563.1 - 0.18 11.5 4.9 9.3 6.0 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat NADH_4Fe-4S PF10589.4 EIM81564.1 - 0.057 12.5 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Inhibitor_I68 PF10468.4 EIM81564.1 - 0.19 11.9 3.9 0.26 11.5 2.7 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Dimer_Tnp_hAT PF05699.9 EIM81565.1 - 2.6e-06 26.9 1.5 1.8e-05 24.2 0.3 2.8 3 1 0 3 3 3 1 hAT family C-terminal dimerisation region Abhydrolase_6 PF12697.2 EIM81567.1 - 2.1e-15 57.2 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81567.1 - 3.1e-05 23.7 0.0 5.2e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81568.1 - 6.4e-09 36.0 0.1 7.7e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81568.1 - 8e-06 25.6 0.0 9.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81569.1 - 0.00011 22.1 0.1 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EIM81571.1 - 2.6e-68 230.6 0.0 1.1e-67 228.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 EIM81572.1 - 5.4e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81572.1 - 9.2e-09 35.1 0.1 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81572.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPP_enzyme_N PF02776.13 EIM81573.1 - 4.5e-35 120.6 0.1 7e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIM81573.1 - 2.8e-21 75.7 0.0 5.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIM81573.1 - 5.8e-13 48.6 0.0 4e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_DerP2_DerF2 PF02221.10 EIM81574.1 - 5e-23 81.8 0.0 5.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 ML domain Lir1 PF07207.6 EIM81575.1 - 0.21 11.7 2.6 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 Light regulated protein Lir1 F-box-like PF12937.2 EIM81577.1 - 4.8e-07 29.3 1.1 1.4e-06 27.9 0.8 1.8 1 0 0 1 1 1 1 F-box-like GbpC PF08363.5 EIM81577.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Glucan-binding protein C F-box-like PF12937.2 EIM81578.1 - 0.00017 21.2 0.2 0.00017 21.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM81578.1 - 0.0007 19.1 0.0 1.9 8.2 0.0 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM81578.1 - 0.084 12.6 0.1 0.33 10.7 0.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat His_Phos_1 PF00300.17 EIM81579.1 - 8.3e-15 55.2 0.2 2.1e-14 53.8 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S19e PF01090.14 EIM81580.1 - 2.7e-55 185.6 0.1 3.1e-55 185.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_60s PF00428.14 EIM81580.1 - 0.022 15.1 5.7 0.036 14.4 4.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Androgen_recep PF02166.11 EIM81580.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 1 0 1 1 1 0 Androgen receptor LAT PF15234.1 EIM81581.1 - 2.2 7.6 21.0 1.3 8.3 6.6 2.1 1 1 1 2 2 2 0 Linker for activation of T-cells F-box-like PF12937.2 EIM81582.1 - 3.3e-09 36.3 1.1 8.9e-09 34.9 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81582.1 - 0.058 13.0 2.4 0.81 9.4 0.2 2.6 2 0 0 2 2 2 0 F-box domain LAT PF15234.1 EIM81584.1 - 4.8 6.5 20.8 3.4e+03 -2.8 14.4 2.3 1 1 0 1 1 1 0 Linker for activation of T-cells Glyco_trans_2_3 PF13632.1 EIM81586.1 - 7.7e-53 179.0 1.1 7.7e-53 179.0 0.8 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM81586.1 - 5.7e-08 32.8 0.0 3.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIM81586.1 - 0.00057 19.6 0.1 0.037 13.7 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM81586.1 - 0.021 14.0 0.0 0.096 11.9 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 LRR_8 PF13855.1 EIM81587.1 - 0.0029 17.3 0.2 0.069 12.9 0.1 2.6 1 1 1 2 2 2 1 Leucine rich repeat CFEM PF05730.6 EIM81589.1 - 7.2e-10 38.5 10.9 1.3e-09 37.6 7.6 1.5 1 0 0 1 1 1 1 CFEM domain GRP PF07172.6 EIM81589.1 - 0.023 15.1 11.5 0.095 13.1 8.0 2.1 1 0 0 1 1 1 0 Glycine rich protein family 7TM-7TMR_HD PF07698.6 EIM81589.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase SKG6 PF08693.5 EIM81589.1 - 0.089 12.1 0.0 0.089 12.1 0.0 3.2 4 0 0 4 4 4 0 Transmembrane alpha-helix domain His_Phos_1 PF00300.17 EIM81590.1 - 7.8e-24 84.5 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-AN1 PF01428.11 EIM81591.1 - 1e-21 76.4 27.0 5.7e-12 45.3 3.9 2.8 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EIM81591.1 - 0.006 16.7 19.4 0.21 11.8 5.8 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain DUF221 PF02714.10 EIM81592.1 - 4.2e-50 170.4 18.3 6.6e-50 169.8 12.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIM81592.1 - 2.3e-18 66.2 0.1 2.3e-18 66.2 0.1 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIM81592.1 - 8.1e-06 26.2 0.1 0.0065 16.9 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EIM81592.1 - 0.064 13.1 0.3 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Phosphate metabolism protein RRM_6 PF14259.1 EIM81592.1 - 0.17 11.8 0.0 0.85 9.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA4 PF04800.7 EIM81593.1 - 3.8e-36 122.9 0.1 4.5e-36 122.7 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region F-box-like PF12937.2 EIM81594.1 - 9.1e-06 25.3 0.5 2.3e-05 23.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like Glyoxalase_2 PF12681.2 EIM81595.1 - 4e-10 40.2 0.0 7.1e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIM81595.1 - 1.1e-05 25.4 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EIM81595.1 - 0.00069 19.5 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EIM81595.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Response_reg PF00072.19 EIM81595.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Response regulator receiver domain Exo_endo_phos PF03372.18 EIM81597.1 - 2.9e-11 43.8 4.0 8.7e-11 42.2 2.7 1.8 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIM81597.1 - 9.8e-05 21.9 0.1 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Abhydrolase_6 PF12697.2 EIM81598.1 - 4.8e-15 56.0 6.5 1.2e-14 54.7 4.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81598.1 - 2.1e-06 27.5 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EIM81598.1 - 0.031 13.4 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 Serine carboxypeptidase Lipase_GDSL PF00657.17 EIM81599.1 - 4e-14 53.0 0.0 5.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIM81599.1 - 2.4e-06 27.7 0.5 4.5e-06 26.9 0.3 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Omega-toxin PF06357.6 EIM81599.1 - 0.047 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Omega-atracotoxin Lipase_GDSL PF00657.17 EIM81600.1 - 8.5e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIM81600.1 - 0.00072 19.7 2.4 0.033 14.3 1.7 2.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 3Beta_HSD PF01073.14 EIM81601.1 - 1.3e-69 234.0 0.0 2.6e-63 213.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM81601.1 - 2.3e-37 128.6 0.0 3.8e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81601.1 - 2e-17 63.7 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81601.1 - 4.7e-14 51.9 0.1 1.5e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIM81601.1 - 2e-13 49.9 0.0 2.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM81601.1 - 7.6e-08 31.5 2.3 2.1e-06 26.8 1.6 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIM81601.1 - 1.9e-05 24.0 0.6 0.00014 21.2 0.4 2.1 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM81601.1 - 0.0015 18.4 1.3 0.01 15.7 0.9 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM81601.1 - 0.0047 16.5 0.3 0.021 14.4 0.2 2.0 1 1 0 1 1 1 1 KR domain DUF1111 PF06537.6 EIM81601.1 - 0.099 10.9 0.1 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1111) TrkA_N PF02254.13 EIM81601.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EIM81601.1 - 0.16 10.9 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Nbl1_Borealin_N PF10444.4 EIM81602.1 - 9.3e-11 40.9 0.1 1.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal 3Beta_HSD PF01073.14 EIM81603.1 - 3.9e-63 212.7 0.0 1.8e-58 197.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM81603.1 - 5.1e-36 124.2 0.0 7.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81603.1 - 3.1e-16 59.9 0.0 1.2e-15 58.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81603.1 - 4.2e-13 48.7 0.0 6.8e-09 35.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIM81603.1 - 1.5e-10 40.4 0.0 2.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM81603.1 - 3.9e-05 22.6 0.7 0.00035 19.5 0.5 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIM81603.1 - 0.00059 19.1 0.4 0.0028 16.9 0.2 2.0 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM81603.1 - 0.0028 17.5 0.2 0.034 14.0 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM81603.1 - 0.019 14.6 0.5 0.37 10.4 0.1 2.2 1 1 1 2 2 2 0 KR domain TrkA_N PF02254.13 EIM81603.1 - 0.046 13.7 0.1 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_L5 PF00281.14 EIM81603.1 - 0.13 12.0 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L5 3Beta_HSD PF01073.14 EIM81604.1 - 2.2e-67 226.6 0.0 4.4e-63 212.6 0.0 2.4 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM81604.1 - 6.7e-38 130.4 0.0 9.3e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81604.1 - 2.9e-17 63.2 0.0 4.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81604.1 - 4.8e-17 61.7 0.0 5.8e-12 45.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIM81604.1 - 2.3e-13 49.6 0.0 3.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EIM81604.1 - 1.3e-05 24.5 0.3 5.5e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM81604.1 - 1.5e-05 24.9 0.8 0.00026 20.9 0.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM81604.1 - 1.9e-05 23.6 1.0 0.00041 19.3 0.7 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EIM81604.1 - 0.00025 20.7 0.8 0.0018 17.9 0.3 2.3 1 1 1 2 2 2 1 KR domain TrkA_N PF02254.13 EIM81604.1 - 0.004 17.1 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EIM81605.1 - 1.2e-20 73.3 0.0 2.4e-19 69.0 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM81605.1 - 7.8e-11 41.8 0.0 2e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM81605.1 - 1.6e-10 40.3 0.0 1.4e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EIM81605.1 - 0.00086 18.2 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIM81605.1 - 0.005 16.8 0.0 0.072 13.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding VWA_3 PF13768.1 EIM81605.1 - 0.022 14.4 0.0 0.38 10.4 0.0 2.5 3 0 0 3 3 3 0 von Willebrand factor type A domain Polysacc_synt_2 PF02719.10 EIM81605.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein POP1 PF06978.6 EIM81606.1 - 1.3e-44 152.1 24.0 8.1e-44 149.5 10.2 3.6 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EIM81606.1 - 1.9e-24 85.3 1.5 1.9e-24 85.3 1.1 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.6 EIM81606.1 - 0.0065 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 EIM81606.1 - 0.035 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain Seryl_tRNA_N PF02403.17 EIM81607.1 - 0.0037 17.2 1.2 0.0055 16.6 0.8 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 EIM81607.1 - 0.011 15.8 2.4 0.026 14.6 1.6 1.6 1 1 0 1 1 1 0 Syntaxin CHASE3 PF05227.8 EIM81607.1 - 0.016 14.8 1.1 0.029 14.0 0.4 1.6 1 1 0 1 1 1 0 CHASE3 domain NPV_P10 PF05531.7 EIM81607.1 - 0.016 15.4 1.1 0.059 13.6 0.7 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.16 EIM81607.1 - 0.019 14.5 0.9 0.027 14.0 0.6 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RRF PF01765.14 EIM81607.1 - 0.021 14.3 0.8 0.033 13.6 0.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Reo_sigmaC PF04582.7 EIM81607.1 - 0.021 14.0 0.1 0.024 13.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EIM81607.1 - 0.024 14.7 1.2 0.042 13.9 0.8 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RP-C PF03428.8 EIM81607.1 - 0.027 13.9 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain IncA PF04156.9 EIM81607.1 - 0.028 14.0 4.8 0.05 13.2 3.3 1.3 1 1 0 1 1 1 0 IncA protein DUF479 PF04336.7 EIM81607.1 - 0.03 14.4 0.3 0.066 13.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF479 ADIP PF11559.3 EIM81607.1 - 0.043 13.7 1.5 0.068 13.0 1.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spore_YpjB PF09577.5 EIM81607.1 - 0.043 13.3 0.2 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) FlgN PF05130.7 EIM81607.1 - 0.05 13.8 1.0 0.07 13.3 0.7 1.2 1 0 0 1 1 1 0 FlgN protein Spc7 PF08317.6 EIM81607.1 - 0.061 11.9 1.6 0.077 11.6 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 EIM81607.1 - 0.068 11.5 0.3 0.082 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MbeD_MobD PF04899.7 EIM81607.1 - 0.074 12.9 0.8 0.21 11.4 0.5 1.8 1 0 0 1 1 1 0 MbeD/MobD like MerR-DNA-bind PF09278.6 EIM81607.1 - 0.16 12.3 1.0 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 MerR, DNA binding Tropomyosin PF00261.15 EIM81607.1 - 0.17 10.9 5.4 0.29 10.1 3.6 1.4 1 1 0 1 1 1 0 Tropomyosin Syntaxin-6_N PF09177.6 EIM81607.1 - 0.19 12.1 1.6 1 9.7 1.0 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 EIM81607.1 - 0.23 11.1 4.7 0.46 10.2 3.2 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.4 EIM81607.1 - 0.36 10.4 3.3 0.72 9.4 1.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2360 PF10152.4 EIM81610.1 - 0.0019 18.5 0.7 0.0019 18.5 0.5 3.1 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) 4HBT_3 PF13622.1 EIM81610.1 - 0.032 13.9 8.8 0.038 13.7 5.5 1.6 1 1 0 1 1 1 0 Thioesterase-like superfamily MscS_TM PF12794.2 EIM81610.1 - 0.034 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Zn_clus PF00172.13 EIM81611.1 - 7.8e-07 28.9 9.7 1.4e-06 28.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIM81611.1 - 0.0017 17.2 1.6 0.0072 15.2 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tom22 PF04281.8 EIM81612.1 - 3.4e-41 139.9 0.1 4e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Nab2 PF11517.3 EIM81612.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DltD_N PF04915.7 EIM81612.1 - 0.086 12.7 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 DltD N-terminal region RicinB_lectin_2 PF14200.1 EIM81613.1 - 2.9e-20 72.5 0.0 1.4e-13 51.0 0.0 4.0 3 1 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIM81613.1 - 8e-06 25.8 1.8 3.6e-05 23.7 0.5 2.7 4 1 0 4 4 4 1 Ricin-type beta-trefoil lectin domain CMAS PF02353.15 EIM81614.1 - 5.5e-62 209.3 1.0 1.7e-49 168.3 0.1 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EIM81614.1 - 5.4e-08 33.2 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM81614.1 - 9.4e-07 28.6 0.0 2.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81614.1 - 1.7e-06 28.6 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81614.1 - 6.8e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM81614.1 - 5.1e-05 23.5 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM81614.1 - 0.00043 19.7 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIM81614.1 - 0.0023 17.5 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EIM81614.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EIM81614.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EIM81614.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EIM81614.1 - 0.057 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PTS_EIIB PF00367.15 EIM81614.1 - 0.075 12.2 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 phosphotransferase system, EIIB Methyltransf_3 PF01596.12 EIM81614.1 - 0.087 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RicinB_lectin_2 PF14200.1 EIM81615.1 - 5.2e-10 39.6 0.0 0.00029 21.1 0.0 3.6 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like GPI-anchored PF10342.4 EIM81617.1 - 2.1e-10 40.9 0.2 4.1e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIM81617.1 - 0.049 13.1 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Lipase_3 PF01764.20 EIM81619.1 - 1.7e-25 89.2 0.0 2.5e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIM81619.1 - 0.00028 20.5 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EIM81619.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EIM81619.1 - 0.0085 15.4 0.1 0.068 12.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) UPF0227 PF05728.7 EIM81619.1 - 0.0094 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EIM81619.1 - 0.037 13.5 0.1 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM81619.1 - 0.04 13.6 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EIM81619.1 - 0.055 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GPI-anchored PF10342.4 EIM81620.1 - 7.7e-10 39.1 1.2 1.1e-09 38.6 0.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SIR2 PF02146.12 EIM81621.1 - 9.3e-53 178.5 0.0 1.3e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family OrfB_Zn_ribbon PF07282.6 EIM81621.1 - 0.15 11.7 0.2 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cullin PF00888.17 EIM81622.1 - 8e-44 150.1 0.0 1.6e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EIM81622.1 - 3.5e-09 36.7 0.0 1.1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 MFS_1 PF07690.11 EIM81623.1 - 1.9e-18 66.3 48.0 2.5e-18 65.9 30.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIM81624.1 - 1.6e-16 60.0 48.8 2.2e-16 59.5 31.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily UCH PF00443.24 EIM81625.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GPI-anchored PF10342.4 EIM81626.1 - 2.6e-10 40.6 2.6 3e-10 40.4 1.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3304 PF11745.3 EIM81626.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) DUF4448 PF14610.1 EIM81626.1 - 0.028 13.8 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) A_deaminase PF00962.17 EIM81628.1 - 1.4e-109 366.0 0.8 1.9e-109 365.6 0.6 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Potex_coat PF06184.6 EIM81629.1 - 0.0027 17.0 0.6 0.0055 16.0 0.1 1.7 1 1 0 2 2 2 1 Potexvirus coat protein Ribosomal_L22 PF00237.14 EIM81630.1 - 2.9e-30 104.2 0.1 4.4e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RICTOR_N PF14664.1 EIM81631.1 - 5.9e-92 308.1 0.9 4.5e-90 301.9 0.4 2.3 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EIM81631.1 - 2.2e-85 285.2 1.6 3.3e-84 281.4 0.1 3.3 3 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EIM81631.1 - 7.7e-32 109.6 0.0 1.2e-30 105.7 0.0 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EIM81631.1 - 1.2e-28 98.8 0.0 1.2e-26 92.4 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EIM81631.1 - 0.15 11.8 0.8 0.32 10.7 0.5 1.5 1 0 0 1 1 1 0 Hr1 repeat Epimerase PF01370.16 EIM81632.1 - 6.4e-23 81.4 0.0 1.3e-22 80.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81632.1 - 4.8e-20 71.4 0.0 9e-20 70.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81632.1 - 1e-18 67.9 0.7 1.7e-18 67.3 0.5 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81632.1 - 1.8e-11 43.4 0.0 3e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM81632.1 - 2.2e-08 33.6 0.5 3.1e-08 33.1 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM81632.1 - 3.6e-06 27.0 2.6 6.8e-06 26.0 1.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM81632.1 - 0.00013 20.9 0.2 0.00091 18.2 0.2 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM81632.1 - 0.00014 20.8 0.1 0.21 10.4 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 EIM81632.1 - 0.0018 17.3 0.2 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EIM81632.1 - 0.016 14.8 3.1 0.088 12.4 2.1 2.0 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 EIM81632.1 - 0.022 14.6 1.2 0.062 13.2 0.9 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GST_N_3 PF13417.1 EIM81633.1 - 1.1e-14 54.3 0.0 2.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81633.1 - 2.6e-09 36.9 0.0 6.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81633.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM81633.1 - 2.7e-05 24.5 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM81633.1 - 0.00059 19.6 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM81633.1 - 0.069 13.3 0.0 0.26 11.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF3154 PF11351.3 EIM81633.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) F-box-like PF12937.2 EIM81634.1 - 7.5e-11 41.5 1.0 7.5e-11 41.5 0.7 2.4 2 0 0 2 2 2 1 F-box-like GST_N_3 PF13417.1 EIM81635.1 - 2e-09 37.5 0.1 3.4e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81635.1 - 2.8e-06 27.2 0.1 4.8e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain D123 PF07065.9 EIM81636.1 - 7.5e-80 268.1 0.0 8.7e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EIM81636.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) DNA_pol_phi PF04931.8 EIM81636.1 - 0.74 7.5 4.6 1 7.0 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi FA_desaturase PF00487.19 EIM81637.1 - 5.3e-25 88.3 19.3 8.7e-25 87.6 13.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIM81637.1 - 0.019 15.0 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF3374 PF11854.3 EIM81637.1 - 0.11 10.7 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Epimerase PF01370.16 EIM81638.1 - 4.6e-20 72.0 0.2 8.8e-20 71.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81638.1 - 1.7e-09 36.7 0.0 2.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81638.1 - 1.6e-06 28.2 1.8 1e-05 25.6 1.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81638.1 - 8.2e-06 24.9 1.8 0.00018 20.5 1.3 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIM81638.1 - 6.4e-05 22.9 3.1 0.0011 18.9 2.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM81638.1 - 0.00011 21.5 0.4 0.00024 20.4 0.3 1.6 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EIM81638.1 - 0.0043 15.9 0.8 0.067 12.0 0.1 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM81638.1 - 0.011 14.6 0.2 0.029 13.2 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 EIM81638.1 - 0.014 15.0 3.5 0.4 10.3 2.4 2.3 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 EIM81639.1 - 7.7e-22 77.8 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81639.1 - 7.5e-08 31.4 0.0 2e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81639.1 - 2.9e-07 30.6 0.9 9.1e-07 29.0 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81639.1 - 6.7e-06 25.2 0.1 3.1e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIM81639.1 - 0.00014 21.8 1.3 0.0012 18.7 0.9 2.2 1 1 0 1 1 1 1 short chain dehydrogenase ATP-grasp_5 PF13549.1 EIM81639.1 - 0.011 14.9 0.4 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Chon_Sulph_att PF06566.6 EIM81639.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain NmrA PF05368.8 EIM81639.1 - 0.03 13.5 0.4 0.047 12.9 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.20 EIM81640.1 - 8.8e-18 64.3 0.0 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 EIM81640.1 - 0.013 15.2 0.3 0.099 12.3 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM81640.1 - 0.015 14.3 0.0 0.039 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIM81640.1 - 0.016 14.2 0.0 0.057 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Acetyltransf_3 PF13302.1 EIM81642.1 - 2.8e-22 79.4 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM81642.1 - 3.5e-16 59.5 0.0 4e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM81642.1 - 1.4e-09 37.8 0.1 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIM81642.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM81642.1 - 1.9e-05 24.6 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM81642.1 - 0.0023 17.6 0.1 0.0043 16.7 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein DUF2205 PF10224.4 EIM81643.1 - 1.5e-12 46.9 0.6 2e-12 46.4 0.4 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EIM81643.1 - 0.012 15.9 0.8 0.014 15.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pox_F11 PF04943.7 EIM81643.1 - 0.03 13.1 0.1 0.033 13.0 0.1 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein Sas10_Utp3 PF04000.10 EIM81643.1 - 0.11 12.7 0.2 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Usp PF00582.21 EIM81644.1 - 2.2e-18 66.8 0.1 2.2e-18 66.8 0.0 2.7 3 0 0 3 3 3 1 Universal stress protein family Acetyltransf_CG PF14542.1 EIM81644.1 - 0.11 12.4 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M3 PF01432.15 EIM81645.1 - 1e-133 446.7 0.0 1.5e-133 446.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EIM81645.1 - 0.02 14.3 0.2 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF1492 PF07374.6 EIM81645.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Pet127 PF08634.5 EIM81646.1 - 3.6e-96 321.5 1.0 3.8e-96 321.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Lumazine_bd_2 PF12893.2 EIM81646.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative lumazine-binding Arf PF00025.16 EIM81647.1 - 2e-42 144.4 0.0 2.3e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIM81647.1 - 7.4e-19 67.7 0.0 9.1e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM81647.1 - 4.8e-14 52.8 0.0 1.8e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EIM81647.1 - 2.1e-09 36.8 0.0 2.5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIM81647.1 - 2.4e-08 33.4 0.0 3.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIM81647.1 - 4.8e-06 25.5 0.2 1.3e-05 24.0 0.0 1.7 1 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EIM81647.1 - 2.1e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM81647.1 - 0.00018 21.0 0.0 0.00054 19.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIM81647.1 - 0.011 15.5 0.5 0.29 10.9 0.5 2.1 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 EIM81647.1 - 0.034 13.6 0.1 7.8 5.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Proteasom_Rpn13 PF04683.8 EIM81648.1 - 3.6e-27 94.2 0.0 5.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pro_isomerase PF00160.16 EIM81649.1 - 6.8e-47 159.5 0.1 1.3e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIM81649.1 - 5.4e-08 32.4 7.6 0.00066 19.4 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 EIM81650.1 - 3e-35 121.8 0.0 7.8e-33 113.9 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 EIM81651.1 - 0.00028 20.5 2.1 0.00069 19.2 0.5 2.3 2 1 0 2 2 2 1 F-box-like GST_N PF02798.15 EIM81652.1 - 2.1e-12 47.0 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIM81652.1 - 2.7e-11 43.5 0.0 7.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81652.1 - 2.6e-09 36.9 0.1 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81652.1 - 0.00036 20.3 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM81652.1 - 0.0006 19.7 0.0 0.00092 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM81652.1 - 0.0017 18.8 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GRASP55_65 PF04495.9 EIM81653.1 - 1.4e-07 31.5 0.0 9.8e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EIM81653.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 PDZ domain Septin PF00735.13 EIM81654.1 - 4.6e-44 150.5 0.0 6.6e-16 58.1 0.0 3.5 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.18 EIM81654.1 - 0.00065 19.6 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM81654.1 - 0.00085 18.8 0.0 0.0024 17.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM81654.1 - 0.0054 17.2 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIM81654.1 - 0.01 15.6 0.3 0.96 9.2 0.1 2.5 1 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 EIM81654.1 - 0.015 15.4 0.0 0.069 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIM81654.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIM81654.1 - 0.054 12.1 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 EIM81654.1 - 0.06 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein CDC45 PF02724.9 EIM81654.1 - 8.1 4.3 5.9 16 3.3 4.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.4 EIM81655.1 - 4.8e-42 143.6 1.5 2.9e-35 121.6 0.0 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family Alg6_Alg8 PF03155.10 EIM81656.1 - 1.9e-127 425.9 20.7 3.2e-99 332.8 5.3 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.17 EIM81657.1 - 1e-11 44.7 0.1 1.8e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EIM81657.1 - 0.0017 18.2 0.0 0.0025 17.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 EIM81657.1 - 0.0022 17.8 0.2 0.0051 16.5 0.1 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Mmp37 PF09139.6 EIM81658.1 - 7.4e-105 350.6 0.0 8.7e-105 350.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 ILVD_EDD PF00920.16 EIM81659.1 - 6.1e-197 655.1 0.0 7.1e-197 654.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Septin PF00735.13 EIM81661.1 - 2e-31 109.0 0.0 1.2e-10 40.9 0.1 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 EIM81661.1 - 3e-18 65.4 26.7 2.3e-09 37.0 7.1 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_phi PF04931.8 EIM81661.1 - 0.31 8.7 8.1 0.54 7.9 5.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.8 EIM81661.1 - 8.4 6.1 14.0 0.58 10.0 3.5 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit F-actin_cap_A PF01267.12 EIM81662.1 - 3.7e-89 298.3 0.0 4.2e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Lact_bio_phlase PF09508.5 EIM81662.1 - 0.056 11.1 0.0 0.066 10.8 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase ICL PF00463.16 EIM81663.1 - 1e-249 829.1 0.4 1.2e-249 828.9 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EIM81663.1 - 1.3e-10 40.9 0.0 2.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 EIM81663.1 - 0.021 14.5 0.1 0.063 13.0 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin TG Glycos_transf_4 PF00953.16 EIM81664.1 - 9.4e-31 106.7 6.1 9.4e-31 106.7 4.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 SET PF00856.23 EIM81665.1 - 6.3e-07 29.8 0.0 2.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 SET domain TilS PF09179.6 EIM81665.1 - 0.064 13.2 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TilS substrate binding domain DUF4470 PF14737.1 EIM81666.1 - 1.6e-22 79.1 0.0 5.1e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM81666.1 - 1.6e-10 40.6 15.9 4e-10 39.4 11.0 1.7 1 0 0 1 1 1 1 MYND finger Malic_M PF03949.10 EIM81667.1 - 2.5e-83 279.5 0.0 3.2e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIM81667.1 - 1.3e-63 213.8 0.0 2e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.2 EIM81668.1 - 5.1e-31 107.8 5.9 1.2e-30 106.6 4.1 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EIM81668.1 - 0.0011 18.8 0.3 0.0016 18.3 0.2 1.2 1 0 0 1 1 1 1 Neugrin BSD PF03909.12 EIM81669.1 - 3.9e-05 23.3 0.1 9.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 BSD domain PTRF_SDPR PF15237.1 EIM81669.1 - 0.03 13.7 0.4 0.03 13.7 0.2 2.6 4 0 0 4 4 4 0 PTRF/SDPR family DUF883 PF05957.8 EIM81669.1 - 0.48 10.8 5.8 4.8 7.6 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Homeobox PF00046.24 EIM81670.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Homeobox domain PRCC PF10253.4 EIM81670.1 - 0.6 10.7 8.7 0.82 10.3 6.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Spb1_C PF07780.7 EIM81670.1 - 1.1 8.6 3.6 0.29 10.5 0.1 1.9 2 1 0 2 2 2 0 Spb1 C-terminal domain ACC_epsilon PF13822.1 EIM81671.1 - 0.41 11.0 0.2 0.41 11.0 0.2 2.9 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit 7TM_GPCR_Srj PF10319.4 EIM81672.1 - 0.034 13.2 0.0 5.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj Arrestin_N PF00339.24 EIM81674.1 - 1.2e-08 34.8 0.0 8.7e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain GST_N_3 PF13417.1 EIM81675.1 - 2.7e-25 88.4 0.0 4.9e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81675.1 - 9.5e-21 73.5 0.0 2.8e-20 72.0 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM81675.1 - 5.7e-13 48.8 0.1 1.7e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81675.1 - 0.0054 16.5 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM81675.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM81675.1 - 0.023 15.1 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EIM81675.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Arm PF00514.18 EIM81675.1 - 0.066 13.0 0.3 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat KAT11 PF08214.6 EIM81676.1 - 1.4e-35 123.0 0.0 5.4e-35 121.1 0.0 1.8 1 1 0 1 1 1 1 Histone acetylation protein Rod_C PF10493.4 EIM81676.1 - 0.22 9.7 0.0 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region DUF4106 PF13388.1 EIM81678.1 - 5.8 5.7 12.9 9.3 5.0 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Zip PF02535.17 EIM81678.1 - 7.5 5.4 14.9 13 4.6 10.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Arrestin_N PF00339.24 EIM81680.1 - 6.5e-13 48.7 0.2 1.8e-11 44.0 0.1 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Alpha-amylase PF00128.19 EIM81681.1 - 7.1e-66 222.7 7.0 1.1e-65 222.1 4.9 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIM81681.1 - 2.8e-15 56.1 0.0 9.7e-15 54.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EIM81681.1 - 0.016 14.0 0.2 0.028 13.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 hDGE_amylase PF14701.1 EIM81681.1 - 0.082 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_7 PF00840.15 EIM81682.1 - 7.1e-208 690.2 27.8 8.4e-208 690.0 19.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pyr_redox_3 PF13738.1 EIM81683.1 - 3.1e-19 69.8 0.0 5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM81683.1 - 3.4e-15 55.2 0.3 1.1e-14 53.5 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM81683.1 - 7.5e-12 44.8 0.0 6.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIM81683.1 - 4.8e-11 42.5 0.0 1.5e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM81683.1 - 1.7e-07 31.3 0.0 9.1e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM81683.1 - 0.028 13.3 0.0 0.061 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM81683.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EIM81683.1 - 0.078 11.8 0.0 3 6.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIM81683.1 - 0.088 12.5 0.4 2.8 7.7 0.3 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Sec16 PF12932.2 EIM81683.1 - 0.13 12.2 0.0 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region FAD_binding_3 PF01494.14 EIM81683.1 - 0.22 10.5 0.1 0.43 9.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fcf2 PF08698.6 EIM81684.1 - 1.2e-20 73.3 0.0 2.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Presenilin PF01080.12 EIM81684.1 - 0.58 8.9 1.6 0.92 8.2 1.1 1.2 1 0 0 1 1 1 0 Presenilin Rgp1 PF08737.5 EIM81684.1 - 3.2 6.7 5.4 4.2 6.3 3.7 1.4 1 1 0 1 1 1 0 Rgp1 ICMT PF04140.9 EIM81686.1 - 1.3e-15 57.3 0.1 3.3e-14 52.8 0.0 2.1 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM81686.1 - 1.4e-14 54.0 0.2 9.9e-14 51.3 0.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EIM81686.1 - 0.00039 19.7 0.2 0.00044 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EIM81686.1 - 0.0078 14.7 0.0 0.016 13.8 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Cullin PF00888.17 EIM81687.1 - 4.7e-190 633.0 13.9 6.5e-190 632.5 9.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIM81687.1 - 1.4e-27 95.2 2.7 3.9e-27 93.8 1.9 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.5 EIM81687.1 - 0.0088 15.6 0.0 0.033 13.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1727) DUF1469 PF07332.6 EIM81688.1 - 0.43 10.3 0.1 0.43 10.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Ubie_methyltran PF01209.13 EIM81690.1 - 8.5e-78 260.6 0.0 1e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIM81690.1 - 1.5e-14 53.8 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM81690.1 - 6.7e-14 51.9 0.0 9.9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM81690.1 - 7.4e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM81690.1 - 4.8e-11 42.9 0.0 1.3e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81690.1 - 1.6e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM81690.1 - 5.9e-09 36.4 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM81690.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIM81690.1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol_A_exo1 PF01612.15 EIM81693.1 - 4.7e-48 162.9 0.1 8.9e-48 162.0 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EIM81693.1 - 6.9e-15 55.1 0.6 6.9e-15 55.1 0.4 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EIM81693.1 - 1.6e-11 43.7 0.1 3.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 HRDC domain H-K_ATPase_N PF09040.6 EIM81693.1 - 0.037 14.1 0.3 0.17 12.0 0.2 2.1 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain PBP PF01161.15 EIM81695.1 - 1.9e-15 56.9 0.0 2.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3846 PF12957.2 EIM81695.1 - 0.0038 16.9 0.0 0.83 9.4 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3846) PBP PF01161.15 EIM81696.1 - 3.7e-16 59.2 0.0 4.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DDE_1 PF03184.14 EIM81697.1 - 3.6e-08 32.8 0.0 4.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM81697.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease PBP PF01161.15 EIM81698.1 - 2.1e-12 47.1 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3846 PF12957.2 EIM81698.1 - 0.023 14.4 0.0 4.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) Peptidase_S9 PF00326.16 EIM81699.1 - 7.5e-40 136.4 0.0 1.1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM81699.1 - 1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIM81699.1 - 3e-06 26.6 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EIM81699.1 - 7.7e-06 25.5 0.1 0.068 12.5 0.0 2.8 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EIM81699.1 - 1.9e-05 24.6 0.0 0.00011 22.1 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EIM81699.1 - 0.0034 17.1 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EIM81699.1 - 0.0046 16.5 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DPPIV_N PF00930.16 EIM81699.1 - 0.012 14.2 0.1 1.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Esterase PF00756.15 EIM81699.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Fibrillarin_2 PF10113.4 EIM81699.1 - 0.019 13.3 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Abhydrolase_4 PF08386.5 EIM81699.1 - 0.026 14.4 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein PQQ_3 PF13570.1 EIM81699.1 - 0.048 13.9 1.7 0.16 12.2 0.2 2.7 2 0 0 2 2 2 0 PQQ-like domain Abhydrolase_3 PF07859.8 EIM81699.1 - 0.11 12.0 0.0 0.6 9.6 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EIM81699.1 - 0.12 11.6 0.0 0.4 9.9 0.0 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase FIST PF08495.5 EIM81701.1 - 2.4e-07 30.0 0.1 9.3e-07 28.1 0.0 2.0 2 1 0 2 2 2 1 FIST N domain Abi PF02517.11 EIM81702.1 - 0.76 9.9 4.0 1.1 9.4 1.5 2.1 2 1 0 2 2 2 0 CAAX protease self-immunity RNA_pol_3_Rpc31 PF11705.3 EIM81702.1 - 0.92 9.4 4.8 1.5 8.7 3.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HCO3_cotransp PF00955.16 EIM81703.1 - 5.4e-62 210.1 6.1 3.1e-33 115.2 1.3 3.0 2 1 1 3 3 3 3 HCO3- transporter family Peptidase_M50 PF02163.17 EIM81703.1 - 0.32 9.9 2.6 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Peptidase family M50 Abhydrolase_5 PF12695.2 EIM81704.1 - 4.5e-18 65.3 0.0 1e-17 64.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81704.1 - 2.8e-16 60.1 0.3 9.8e-16 58.3 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIM81704.1 - 8.2e-06 25.5 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM81704.1 - 0.00016 20.9 0.1 0.0042 16.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EIM81704.1 - 0.0036 17.1 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIM81704.1 - 0.0039 16.7 0.2 0.0093 15.5 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 EIM81704.1 - 0.036 13.5 0.0 1 8.7 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase (FSH1) HATPase_c PF02518.21 EIM81705.1 - 5.4e-24 84.0 0.1 2.6e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.15 EIM81705.1 - 3.4e-22 78.4 0.0 6.9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.19 EIM81705.1 - 3.6e-16 59.1 0.5 1.2e-15 57.4 0.3 2.0 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EIM81705.1 - 2e-13 50.7 0.0 6e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EIM81705.1 - 2.2e-10 40.3 0.7 6.7e-10 38.8 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EIM81705.1 - 2.9e-10 40.5 0.0 9.5e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold p450 PF00067.17 EIM81706.1 - 1.5e-67 228.1 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIM81707.1 - 2.1e-05 24.1 0.1 6.4e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.7 EIM81709.1 - 2.7e-117 392.4 1.0 1.6e-99 333.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 ETF PF01012.16 EIM81710.1 - 5.4e-30 104.2 0.3 7.5e-30 103.8 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_10 PF12846.2 EIM81710.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain zf-RING_2 PF13639.1 EIM81711.1 - 1.3e-13 50.5 5.2 2e-13 49.9 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM81711.1 - 1.8e-09 37.5 2.8 3.3e-09 36.7 1.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM81711.1 - 1.9e-08 34.1 4.1 3e-08 33.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM81711.1 - 2e-08 33.8 3.6 3.1e-08 33.2 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM81711.1 - 1.8e-07 30.6 4.5 2.8e-07 30.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM81711.1 - 2.1e-06 27.2 2.7 3.7e-06 26.4 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM81711.1 - 0.00013 21.7 1.2 0.00026 20.7 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EIM81711.1 - 0.0062 16.5 2.7 0.01 15.7 1.9 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.1 EIM81711.1 - 0.012 15.1 5.1 0.021 14.4 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EIM81711.1 - 0.022 14.4 2.8 0.052 13.2 1.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EIM81711.1 - 0.023 14.7 5.4 0.038 14.0 3.8 1.3 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EIM81711.1 - 0.79 9.4 4.7 1.3 8.8 3.3 1.3 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EIM81711.1 - 1.4 8.9 2.8 2.7 8.0 2.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF1272 PF06906.6 EIM81711.1 - 1.6 8.6 5.2 3.8 7.4 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) His_Phos_2 PF00328.17 EIM81713.1 - 2e-08 33.9 0.5 9e-07 28.5 0.3 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tyrosinase PF00264.15 EIM81714.1 - 6.8e-34 117.9 2.4 9.1e-34 117.5 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DIOX_N PF14226.1 EIM81716.1 - 1.4e-22 80.3 0.2 3.4e-22 79.1 0.1 1.6 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM81716.1 - 1.3e-19 70.2 0.0 2.8e-19 69.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2890 PF11081.3 EIM81717.1 - 0.5 10.3 5.0 3.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) DUF605 PF04652.11 EIM81718.1 - 0.21 10.9 12.9 0.3 10.4 9.0 1.2 1 0 0 1 1 1 0 Vta1 like PAP1 PF08601.5 EIM81718.1 - 4.5 6.8 9.2 0.21 11.2 1.8 1.9 2 0 0 2 2 2 0 Transcription factor PAP1 MFS_1 PF07690.11 EIM81719.1 - 1.3e-49 168.8 15.4 1.8e-49 168.3 10.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81719.1 - 3.1e-11 42.5 27.0 2.6e-08 32.9 6.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter Ctr PF04145.10 EIM81719.1 - 0.019 15.0 1.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 0 Ctr copper transporter family OATP PF03137.15 EIM81719.1 - 0.2 9.6 13.6 0.0049 14.9 2.7 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2244 PF10003.4 EIM81719.1 - 3.2 7.1 7.3 0.15 11.3 0.2 2.4 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) GST_N_3 PF13417.1 EIM81720.1 - 2.4e-10 40.5 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM81720.1 - 4.2e-10 39.6 0.0 8.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM81720.1 - 1.1e-08 34.9 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM81720.1 - 8.5e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81720.1 - 8.6e-07 28.7 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1762 PF08574.5 EIM81721.1 - 7.9e-06 26.2 11.5 7.9e-06 26.2 8.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1762) Homeobox PF00046.24 EIM81722.1 - 0.00045 19.7 0.0 0.00093 18.7 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain F-box-like PF12937.2 EIM81723.1 - 1.3e-05 24.7 0.2 3.2e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM81724.1 - 2.9e-05 23.7 1.9 8.8e-05 22.1 1.3 1.9 1 0 0 1 1 1 1 F-box-like Peptidase_M16 PF00675.15 EIM81725.1 - 1.4e-55 187.1 1.5 1.8e-55 186.8 0.4 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIM81725.1 - 6.5e-42 143.2 0.0 5.4e-40 137.0 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain CoA_transf_3 PF02515.12 EIM81727.1 - 6.3e-30 103.8 0.0 1e-25 90.1 0.0 2.4 2 0 0 2 2 2 2 CoA-transferase family III zf-FCS PF06467.9 EIM81728.1 - 0.001 18.6 5.7 0.17 11.5 0.5 2.7 2 2 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.1 EIM81728.1 - 0.039 14.2 10.7 0.7 10.3 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Opy2 PF09463.5 EIM81728.1 - 4.5 7.4 10.4 0.41 10.7 2.4 2.3 2 0 0 2 2 2 0 Opy2 protein DUF566 PF04484.7 EIM81729.1 - 0.75 9.2 6.3 0.94 8.9 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 EIM81729.1 - 1.6 8.5 11.2 1.8 8.3 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 EIM81730.1 - 4e-67 226.0 0.0 5.3e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81730.1 - 2.1e-41 141.7 0.0 3.6e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81730.1 - 5.2e-10 38.7 0.0 2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM81730.1 - 0.0043 16.8 0.1 0.64 9.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIM81730.1 - 0.023 13.7 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIM81730.1 - 0.11 11.8 0.0 0.4 9.9 0.0 1.8 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL TFIIA PF03153.8 EIM81730.1 - 0.12 12.2 4.9 0.15 11.9 3.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_jaz PF12171.3 EIM81731.1 - 2.2e-06 27.6 3.7 0.023 14.8 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EIM81731.1 - 0.00012 22.1 13.2 0.0063 16.7 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIM81731.1 - 0.00063 19.5 5.6 0.037 13.9 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIM81731.1 - 0.0012 18.9 12.7 0.0039 17.4 2.0 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EIM81731.1 - 0.0021 18.2 2.9 0.02 15.0 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 EIM81731.1 - 0.054 13.5 1.5 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 zinc-finger zf-H2C2_2 PF13465.1 EIM81731.1 - 0.21 11.9 7.9 0.23 11.8 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain TFIIF_alpha PF05793.7 EIM81731.1 - 0.44 8.8 3.3 0.74 8.1 2.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF164 PF02591.10 EIM81731.1 - 0.49 10.2 3.5 2.6 7.9 0.3 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain DZR PF12773.2 EIM81731.1 - 2.5 8.0 6.5 11 5.9 4.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon Pectinesterase PF01095.14 EIM81732.1 - 4.1e-38 130.6 3.2 2.9e-31 108.1 0.8 2.0 2 0 0 2 2 2 2 Pectinesterase ParA PF10609.4 EIM81733.1 - 4.5e-31 106.5 0.1 7.1e-31 105.9 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIM81733.1 - 9.3e-17 61.0 0.0 2e-16 60.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIM81733.1 - 2.9e-08 33.8 0.0 1.4e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EIM81733.1 - 1.7e-06 27.3 0.0 2.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EIM81733.1 - 4.1e-05 22.7 0.2 0.0015 17.6 0.1 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EIM81733.1 - 0.0075 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIM81733.1 - 0.014 14.6 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EIM81733.1 - 0.034 13.7 0.3 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIM81734.1 - 3.6e-18 65.9 0.0 9.7e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIM81734.1 - 2.9e-11 43.3 0.0 1.9e-10 40.7 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM81734.1 - 1.6e-09 37.4 1.3 2.6e-09 36.8 0.1 2.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM81734.1 - 0.00021 21.7 0.1 0.05 14.1 0.0 2.8 1 1 1 2 2 2 1 Miro-like protein IIGP PF05049.8 EIM81734.1 - 0.0049 15.7 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EIM81734.1 - 0.005 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EIM81734.1 - 0.055 12.4 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin HSP9_HSP12 PF04119.7 EIM81734.1 - 0.36 10.9 4.0 0.18 11.8 0.3 2.4 2 0 0 2 2 2 0 Heat shock protein 9/12 Syntaxin_2 PF14523.1 EIM81736.1 - 1.7e-21 76.1 1.3 1.7e-21 76.1 0.9 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EIM81736.1 - 3.5e-18 65.0 2.0 7.9e-18 63.9 0.2 2.2 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.16 EIM81736.1 - 0.024 14.2 0.1 0.092 12.3 0.1 2.0 1 0 0 1 1 1 0 Synaptobrevin MCPsignal PF00015.16 EIM81736.1 - 0.029 13.9 9.2 0.058 12.9 4.7 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Herpes_US9 PF06072.6 EIM81736.1 - 0.19 11.5 1.2 0.34 10.7 0.8 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 FlaC_arch PF05377.6 EIM81736.1 - 0.31 10.9 1.6 76 3.3 0.0 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF912 PF06024.7 EIM81736.1 - 0.59 10.2 3.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TerB-C PF15615.1 EIM81736.1 - 1.2 9.3 7.5 1.7 8.8 4.7 1.6 1 1 0 1 1 1 0 TerB-C domain DUF3708 PF12501.3 EIM81736.1 - 3.9 7.2 6.8 11 5.7 2.7 2.7 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DAO PF01266.19 EIM81737.1 - 5.8e-48 163.5 0.0 8.6e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM81737.1 - 6.4e-08 31.8 0.6 0.00075 18.4 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIM81737.1 - 5.3e-07 29.0 0.4 5.9e-06 25.6 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM81737.1 - 1.9e-05 23.8 0.2 0.00018 20.6 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM81737.1 - 6e-05 23.0 0.1 0.001 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM81737.1 - 0.0052 15.7 0.3 0.41 9.5 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EIM81737.1 - 0.0074 15.9 0.7 0.021 14.4 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIM81737.1 - 0.012 15.6 0.3 0.036 14.0 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM81737.1 - 0.023 15.0 0.3 0.078 13.3 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM81737.1 - 0.027 13.3 0.1 0.11 11.3 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIM81737.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM81737.1 - 0.11 10.9 1.0 0.19 10.1 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.23 EIM81740.1 - 1.4e-77 260.8 0.0 1.8e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM81740.1 - 5.5e-05 24.0 0.0 0.00025 21.9 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Meth_synt_2 PF01717.13 EIM81742.1 - 6.7e-17 61.4 0.0 3.3e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM81742.1 - 8.1e-06 25.3 0.0 0.011 15.0 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Arginase PF00491.16 EIM81742.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Arginase family Meth_synt_2 PF01717.13 EIM81743.1 - 1.3e-20 73.6 0.0 3.4e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM81743.1 - 6.1e-11 42.1 0.0 0.00078 18.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF500 PF04366.7 EIM81745.1 - 1e-44 151.0 0.0 1.7e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Phosphodiest PF01663.17 EIM81746.1 - 1.2e-68 232.0 2.0 1.6e-68 231.7 1.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIM81746.1 - 0.05 12.7 0.0 6.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Sulfatase Lipase_GDSL_2 PF13472.1 EIM81747.1 - 1.5e-12 48.0 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM81747.1 - 3.3e-05 23.8 0.1 0.14 11.9 0.0 2.4 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EIM81747.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 EIM81748.1 - 2.5e-73 246.4 0.0 3.6e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81748.1 - 4.9e-35 120.8 0.0 9.1e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM81748.1 - 0.00049 19.1 0.0 0.00085 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.8 EIM81748.1 - 1.5 8.6 14.9 1.8 8.3 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CHAT PF12770.2 EIM81749.1 - 3.1e-28 98.7 0.2 7.6e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM81749.1 - 3.2e-05 23.7 6.4 0.022 14.7 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM81749.1 - 5.8e-05 22.8 5.6 0.37 10.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM81749.1 - 0.057 13.0 0.0 25 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM81749.1 - 0.09 12.7 0.7 84 3.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EIM81751.1 - 4.6e-39 134.1 44.3 4e-35 121.1 14.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81751.1 - 7.7e-17 61.0 10.4 1.6e-16 59.9 7.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM81751.1 - 2.9e-06 25.9 15.5 0.0011 17.4 0.3 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EIM81751.1 - 9e-05 20.8 1.6 0.00018 19.8 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EIM81751.1 - 0.0038 16.9 4.1 1.1 9.0 0.0 3.5 3 1 0 3 3 3 2 MFS_1 like family DUF2419 PF10343.4 EIM81752.1 - 5.3e-84 281.8 0.0 6.9e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) SNF5 PF04855.7 EIM81753.1 - 7.6e-57 192.5 5.5 7.6e-56 189.3 3.8 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DNA_pol_B_palm PF14792.1 EIM81754.1 - 5.8e-14 52.0 0.0 5.2e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase beta palm HHH_8 PF14716.1 EIM81754.1 - 6.8e-12 45.4 0.3 5.3e-11 42.5 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EIM81754.1 - 2e-11 43.3 0.1 1.4e-10 40.7 0.1 2.3 2 1 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EIM81754.1 - 2.3e-08 33.4 0.0 5.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EIM81754.1 - 9e-05 22.5 0.0 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EIM81754.1 - 0.0015 18.7 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 EIM81754.1 - 0.0026 17.6 0.7 0.013 15.3 0.0 2.4 3 0 0 3 3 3 1 Pathogenicity locus IMS_HHH PF11798.3 EIM81754.1 - 0.0027 17.6 0.2 10 6.3 0.0 3.8 3 0 0 3 3 3 2 IMS family HHH motif HHH_3 PF12836.2 EIM81754.1 - 0.019 14.9 0.0 1.5 8.7 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix motif WD40 PF00400.27 EIM81755.1 - 2e-126 407.8 43.9 5.1e-12 45.1 0.8 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat DUF2235 PF09994.4 EIM81755.1 - 1.1e-20 74.2 0.2 2.4e-11 43.5 0.0 2.4 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) PQQ_2 PF13360.1 EIM81755.1 - 7.6e-09 35.3 2.4 0.0015 18.0 0.1 4.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EIM81755.1 - 4.8e-07 28.2 7.3 0.096 10.7 0.0 7.3 1 1 3 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIM81755.1 - 1.9e-06 27.4 0.5 2.5 7.8 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIM81755.1 - 7.4e-06 26.0 0.5 15 6.0 0.0 6.9 7 1 0 7 7 7 1 PQQ-like domain BBS2_Mid PF14783.1 EIM81755.1 - 1.3e-05 24.9 0.0 2.3 8.0 0.0 5.5 5 2 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EIM81755.1 - 0.00038 19.3 13.5 1.8 7.2 0.6 7.3 1 1 5 6 6 6 2 Nup133 N terminal like DUF1652 PF07865.6 EIM81755.1 - 0.096 12.2 0.0 7.7 6.2 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1652) DUF2141 PF09912.4 EIM81755.1 - 0.11 12.1 0.0 3.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) LRR_6 PF13516.1 EIM81756.1 - 1e-17 62.1 9.6 0.056 13.5 0.4 7.1 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.2 EIM81756.1 - 1.3e-15 56.5 10.4 0.0034 16.9 0.3 6.6 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM81756.1 - 2e-06 27.4 8.4 0.26 11.0 0.0 4.5 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EIM81756.1 - 7.9e-06 25.2 7.3 7.7 6.9 0.4 6.8 6 2 1 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 EIM81756.1 - 0.0014 18.5 9.8 24 5.7 0.1 7.1 8 0 0 8 8 8 1 Leucine rich repeat DUF3605 PF12239.3 EIM81757.1 - 2.5e-25 89.1 2.0 1.2e-10 41.5 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) zf-CHY PF05495.7 EIM81759.1 - 4.5e-16 58.7 17.4 5.9e-16 58.3 12.0 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EIM81759.1 - 0.0065 16.2 8.1 0.15 11.8 2.7 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIM81759.1 - 0.031 13.7 9.0 0.11 11.9 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EIM81759.1 - 0.032 13.9 2.7 0.11 12.3 1.9 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-FPG_IleRS PF06827.9 EIM81759.1 - 0.033 13.8 0.5 0.033 13.8 0.4 2.4 2 1 0 2 2 1 0 Zinc finger found in FPG and IleRS HypA PF01155.14 EIM81759.1 - 0.042 13.5 1.4 0.042 13.5 1.0 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIM81759.1 - 0.073 12.8 11.6 0.44 10.3 8.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon Tmemb_55A PF09788.4 EIM81759.1 - 0.084 11.9 5.7 0.096 11.8 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A C1_4 PF07975.7 EIM81759.1 - 0.15 12.1 12.9 0.27 11.2 3.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zf-TFIIB PF13453.1 EIM81759.1 - 0.18 11.0 3.2 3.7 6.8 1.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Cys_rich_KTR PF14205.1 EIM81759.1 - 0.22 11.0 7.5 1.4 8.4 0.1 2.8 1 1 1 2 2 2 0 Cysteine-rich KTR Zn-ribbon_8 PF09723.5 EIM81759.1 - 0.29 11.1 14.7 0.23 11.4 2.6 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EIM81759.1 - 0.29 10.3 9.0 1.9 7.8 3.0 2.7 2 1 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EIM81759.1 - 1.3 8.9 7.9 18 5.1 2.5 3.3 2 1 0 2 2 2 0 PhnA Zinc-Ribbon TFIIS_C PF01096.13 EIM81759.1 - 1.6 8.3 9.2 4.6 6.9 0.3 3.5 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-RING_3 PF14369.1 EIM81759.1 - 1.7 8.7 12.1 0.82 9.7 2.1 3.1 1 1 2 3 3 3 0 zinc-finger DRP PF06044.7 EIM81759.1 - 2 7.3 4.8 1.3 7.9 0.8 1.9 1 1 1 2 2 2 0 Dam-replacing family zinc_ribbon_4 PF13717.1 EIM81759.1 - 2.2 8.0 18.1 2.3 7.9 0.1 4.0 4 1 0 4 4 4 0 zinc-ribbon domain Evr1_Alr PF04777.8 EIM81759.1 - 2.9 7.8 9.2 24 4.8 6.4 2.5 1 1 0 1 1 1 0 Erv1 / Alr family Ogr_Delta PF04606.7 EIM81759.1 - 3.3 7.4 9.1 7.3 6.3 0.1 3.1 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Trm112p PF03966.11 EIM81759.1 - 3.7 7.9 5.2 26 5.2 0.9 2.8 2 1 0 2 2 2 0 Trm112p-like protein zinc_ribbon_5 PF13719.1 EIM81759.1 - 5 6.7 18.1 2.8 7.5 0.1 4.0 4 1 0 4 4 4 0 zinc-ribbon domain Ribosomal_L37ae PF01780.14 EIM81759.1 - 6.3 6.7 6.0 4.8 7.1 1.9 2.0 1 1 1 2 2 2 0 Ribosomal L37ae protein family Mob1_phocein PF03637.12 EIM81760.1 - 1.2e-65 220.4 0.7 1.5e-65 220.1 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans PF04082.13 EIM81762.1 - 7.4e-13 47.9 0.8 1.2e-12 47.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM81762.1 - 1.2e-07 31.5 10.2 2.9e-07 30.2 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EIM81762.1 - 7.4e-06 25.9 18.4 0.00042 20.4 2.1 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM81762.1 - 2e-05 24.6 2.3 2e-05 24.6 1.6 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIM81762.1 - 0.0016 18.7 3.1 0.0016 18.7 2.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Flavoprotein PF02441.14 EIM81763.1 - 1.2e-44 151.1 0.1 1.4e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Pex24p PF06398.6 EIM81764.1 - 1.3e-22 80.1 4.4 1.3e-22 80.1 3.1 1.9 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 EIM81764.1 - 0.049 13.1 3.5 3.3 7.1 0.3 2.3 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal AA_permease PF00324.16 EIM81765.1 - 3.1e-107 358.8 46.1 3.9e-107 358.5 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM81765.1 - 1.2e-35 122.9 48.2 1.6e-35 122.5 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C3HC4_2 PF13923.1 EIM81767.1 - 3.9e-06 26.7 5.3 6.8e-06 26.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM81767.1 - 0.0001 22.0 5.8 0.00017 21.3 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM81767.1 - 0.0061 16.1 3.8 0.0096 15.5 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM81767.1 - 0.068 12.8 6.9 0.11 12.2 4.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM81767.1 - 0.089 12.5 5.0 0.16 11.7 3.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EIM81767.1 - 0.14 12.0 3.5 0.47 10.3 2.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIM81767.1 - 0.19 11.3 5.0 1.6 8.3 3.5 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EIM81767.1 - 0.55 9.7 4.5 1 8.9 3.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger tRNA_int_end_N2 PF12928.2 EIM81768.1 - 5.2e-19 67.4 0.0 8.3e-19 66.8 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EIM81768.1 - 0.059 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain CBM_5_12 PF02839.9 EIM81769.1 - 8.3e-12 44.4 6.3 3.2e-11 42.6 4.3 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_18 PF00704.23 EIM81769.1 - 3.6e-09 36.5 2.5 4.8e-09 36.1 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.2 EIM81770.1 - 0.00027 20.5 0.0 0.0012 18.5 0.0 2.2 1 1 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EIM81771.1 - 8.4e-33 113.5 20.9 1e-32 113.2 13.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.10 EIM81771.1 - 0.042 13.8 0.3 0.042 13.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family TM140 PF14985.1 EIM81771.1 - 0.26 10.9 5.9 0.39 10.3 0.2 2.5 1 1 1 2 2 2 0 TM140 protein family Lactamase_B_2 PF12706.2 EIM81772.1 - 1.2e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIM81772.1 - 4.3e-12 46.0 0.0 2.2e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM81772.1 - 7.8e-06 25.6 0.0 4e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 EIM81773.1 - 3.4e-11 42.4 79.3 8.8e-10 37.8 26.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EIM81774.1 - 1e-16 61.2 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM81774.1 - 5.4e-09 35.9 0.0 7.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM81774.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM81774.1 - 0.0002 20.9 0.0 0.0004 19.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81774.1 - 0.00093 19.2 0.5 0.0061 16.5 0.2 2.2 2 1 0 2 2 2 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EIM81774.1 - 0.0051 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EIM81774.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EIM81774.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EIM81774.1 - 0.12 12.6 0.2 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding SKN1 PF03935.10 EIM81775.1 - 1.2e-181 604.2 11.7 1.4e-181 604.0 8.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sas10 PF09368.5 EIM81776.1 - 2e-24 85.5 3.7 2e-24 85.5 2.6 3.3 5 0 0 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EIM81776.1 - 1.9e-07 31.1 0.9 1.9e-07 31.1 0.6 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Pneumo_att_G PF05539.6 EIM81776.1 - 8.4 5.6 7.2 7.2 5.8 1.0 2.2 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G MIP-T3 PF10243.4 EIM81777.1 - 5.8 5.2 25.9 9.3 4.5 18.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3415 PF11895.3 EIM81778.1 - 4.2e-30 103.4 2.6 7.5e-30 102.6 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 EIM81778.1 - 2.9e-26 92.3 0.0 7.7e-26 90.9 0.0 1.7 1 1 1 2 2 2 1 Peroxidase DUF3415 PF11895.3 EIM81779.1 - 5e-29 99.9 2.6 5e-29 99.9 1.8 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 EIM81779.1 - 2.4e-25 89.3 0.3 3.9e-25 88.6 0.0 1.5 2 0 0 2 2 2 1 Peroxidase Glyco_hydro_28 PF00295.12 EIM81780.1 - 4.4e-26 91.6 0.3 5.6e-26 91.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EIM81780.1 - 2.2e-05 24.6 1.2 6.2e-05 23.2 0.8 1.8 1 1 0 1 1 1 1 Pectate lyase superfamily protein Pkinase_C PF00433.19 EIM81781.1 - 0.022 15.2 1.9 0.035 14.6 1.4 1.3 1 0 0 1 1 1 0 Protein kinase C terminal domain SWIM PF04434.12 EIM81783.1 - 0.34 10.4 3.6 0.9 9.0 2.5 1.7 1 0 0 1 1 1 0 SWIM zinc finger Arm PF00514.18 EIM81785.1 - 2.1e-08 33.6 0.2 0.0045 16.7 0.0 4.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EIM81786.1 - 8.8e-09 34.8 0.0 9.1e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM81786.1 - 0.0096 15.0 0.0 0.0096 15.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_N PF08240.7 EIM81787.1 - 4.5e-22 77.8 4.0 9.1e-22 76.8 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM81787.1 - 5.3e-14 51.8 0.5 9.4e-13 47.8 0.1 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM81787.1 - 0.0032 18.3 0.0 0.0053 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1212 PF06738.7 EIM81788.1 - 1.1e-38 132.6 1.1 1.1e-38 132.6 0.8 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM81788.1 - 9.6e-19 67.6 8.0 9.6e-19 67.6 5.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Methyltransf_25 PF13649.1 EIM81789.1 - 0.00056 20.2 0.2 0.0035 17.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 EIM81791.1 - 1.2e-14 54.6 3.6 2.5e-14 53.5 1.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81791.1 - 2.6e-11 43.7 0.2 1e-10 41.8 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81791.1 - 1.5e-06 27.9 0.4 5.9e-06 26.0 0.3 1.9 1 1 0 1 1 1 1 KR domain RNA_lig_T4_1 PF09511.5 EIM81792.1 - 6.3e-75 251.4 0.0 1.2e-74 250.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EIM81792.1 - 1.7e-24 86.6 0.0 2.8e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EIM81792.1 - 1e-15 57.6 0.0 2.8e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain Protocadherin PF08374.6 EIM81792.1 - 0.77 9.3 2.9 1.6 8.3 2.0 1.4 1 0 0 1 1 1 0 Protocadherin WD40 PF00400.27 EIM81795.1 - 0.17 11.7 1.0 2.1 8.3 0.1 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Flavin_Reduct PF01613.13 EIM81796.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain p450 PF00067.17 EIM81797.1 - 2.8e-66 223.9 0.0 3.1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM81798.1 - 9.6e-67 225.4 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prp18 PF02840.10 EIM81798.1 - 0.046 13.5 0.3 0.082 12.7 0.2 1.3 1 0 0 1 1 1 0 Prp18 domain NAD_binding_4 PF07993.7 EIM81799.1 - 1e-35 122.9 0.0 1.4e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM81799.1 - 2.4e-31 108.5 0.0 1.3e-30 106.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EIM81799.1 - 5.7e-09 35.7 0.0 8.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM81799.1 - 0.00037 20.7 0.0 0.00086 19.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EIM81799.1 - 0.035 12.9 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM81799.1 - 0.062 12.1 0.0 6.2 5.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EIM81800.1 - 1.8e-22 79.2 0.3 3.7e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM81800.1 - 2.9e-06 28.2 0.0 4.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EIM81800.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EIM81800.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding GMC_oxred_N PF00732.14 EIM81801.1 - 1.6e-46 158.8 0.0 2.8e-40 138.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM81801.1 - 2.1e-31 109.1 0.0 4.3e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM81801.1 - 0.025 13.4 0.0 0.89 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1943 PF09172.6 EIM81803.1 - 0.00012 21.0 2.4 0.00017 20.5 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) LEA_2 PF03168.8 EIM81803.1 - 0.17 12.3 14.7 9.2 6.7 10.2 2.4 1 1 0 1 1 1 0 Late embryogenesis abundant protein NMD3 PF04981.8 EIM81803.1 - 0.55 9.3 10.0 0.84 8.6 6.9 1.2 1 0 0 1 1 1 0 NMD3 family VWD PF00094.20 EIM81803.1 - 1.3 9.1 7.7 2.3 8.3 5.4 1.4 1 0 0 1 1 1 0 von Willebrand factor type D domain DUF3156 PF11354.3 EIM81803.1 - 1.8 7.8 4.7 9.3 5.6 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3156) E1_DerP2_DerF2 PF02221.10 EIM81803.1 - 4.1 7.6 10.8 23 5.2 7.2 2.2 1 1 1 2 2 2 0 ML domain CBM_4_9 PF02018.12 EIM81803.1 - 6.6 6.7 13.0 6.6 6.7 2.5 2.2 1 1 1 2 2 2 0 Carbohydrate binding domain MFS_1 PF07690.11 EIM81804.1 - 4.3e-28 98.0 49.4 4.3e-28 98.0 34.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EIM81805.1 - 1.2e-34 119.6 0.0 2.2e-34 118.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EIM81806.1 - 8.3e-26 90.7 12.7 1.1e-25 90.3 8.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EIM81807.1 - 5e-52 176.9 0.0 9.8e-52 175.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EIM81808.1 - 5.5e-61 205.8 0.0 6.9e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EIM81809.1 - 3.2e-17 62.5 0.0 4.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM81809.1 - 3e-07 30.6 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EIM81809.1 - 0.0022 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EIM81809.1 - 0.0051 16.7 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EIM81809.1 - 0.031 12.9 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIM81809.1 - 0.058 12.3 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CHAT PF12770.2 EIM81810.1 - 6e-22 78.1 0.1 7.4e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 CHAT domain DUF3430 PF11912.3 EIM81812.1 - 0.046 13.5 3.8 0.061 13.1 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) WD40 PF00400.27 EIM81816.1 - 5.4e-05 22.9 0.1 0.042 13.7 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat adh_short PF00106.20 EIM81817.1 - 3.5e-22 79.0 0.4 2.3e-21 76.4 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM81817.1 - 3e-10 40.0 0.5 1.8e-09 37.5 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EIM81817.1 - 3.4e-07 29.9 0.0 4.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM81817.1 - 0.00012 21.0 0.1 0.00021 20.2 0.1 1.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIM81817.1 - 0.0018 18.3 0.2 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EIM81817.1 - 0.0038 17.0 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EIM81817.1 - 0.023 13.5 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIM81817.1 - 0.086 11.5 0.1 0.2 10.3 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 EIM81817.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 EIM81817.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EIM81820.1 - 6.7e-20 71.6 0.0 3.3e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM81820.1 - 4.7e-10 39.4 0.0 3.5e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIM81820.1 - 9.3e-07 28.8 0.0 2.5e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM81820.1 - 2.9e-06 26.8 0.1 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81820.1 - 0.00055 19.9 0.0 0.0065 16.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIM81820.1 - 0.00062 18.7 0.1 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIM81820.1 - 0.0041 17.2 0.1 0.0095 16.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SMC_hinge PF06470.8 EIM81820.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain HAD PF12710.2 EIM81820.1 - 0.061 13.4 0.1 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Saccharop_dh PF03435.13 EIM81820.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 EIM81821.1 - 5.7e-21 75.1 0.0 1.5e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM81821.1 - 4.4e-09 36.2 0.0 9.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM81821.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM81821.1 - 0.0027 17.1 0.1 0.0063 15.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM81821.1 - 0.0043 17.0 0.1 0.014 15.4 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 EIM81821.1 - 0.026 14.7 0.1 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EIM81821.1 - 0.035 12.8 0.2 0.082 11.5 0.1 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIM81821.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM81822.1 - 4.3e-21 75.5 0.3 2.4e-20 73.1 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM81822.1 - 4.8e-11 42.6 0.3 1.9e-10 40.6 0.3 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EIM81822.1 - 8.1e-10 38.5 0.1 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIM81822.1 - 3.6e-06 26.1 0.1 4.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EIM81822.1 - 0.0001 22.1 0.2 0.00017 21.4 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM81822.1 - 0.00029 20.9 0.2 0.0016 18.4 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EIM81822.1 - 0.0073 16.3 0.7 0.025 14.6 0.2 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EIM81822.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 EIM81822.1 - 0.025 13.5 0.1 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase SMC_hinge PF06470.8 EIM81822.1 - 0.044 13.7 0.1 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain 3Beta_HSD PF01073.14 EIM81822.1 - 0.065 11.9 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.17 EIM81823.1 - 2.2e-12 47.5 0.0 9.2e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 EIM81823.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3530 PF12048.3 EIM81823.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) AAA_16 PF13191.1 EIM81824.1 - 1.5e-07 31.6 0.4 9.3e-07 29.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain C2 PF00168.25 EIM81824.1 - 1.2e-05 24.9 0.0 4.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain AAA_19 PF13245.1 EIM81824.1 - 1.8e-05 24.3 0.0 0.00015 21.4 0.0 2.4 2 1 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EIM81824.1 - 2.4e-05 24.4 0.0 0.00034 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIM81824.1 - 0.00067 19.3 0.0 0.0024 17.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EIM81824.1 - 0.0065 15.3 0.0 0.064 12.1 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 EIM81824.1 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EIM81824.1 - 0.029 14.0 0.1 2.4 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 EIM81824.1 - 0.042 13.7 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Torsin End_beta_propel PF12217.3 EIM81824.1 - 0.054 12.1 0.1 0.14 10.7 0.0 1.6 2 0 0 2 2 2 0 Catalytic beta propeller domain of bacteriophage endosialidase IstB_IS21 PF01695.12 EIM81824.1 - 0.069 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 EIM81824.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aldedh PF00171.17 EIM81826.1 - 1.9e-182 606.7 0.2 2.1e-182 606.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM81826.1 - 0.0032 16.2 0.0 0.0056 15.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 EIM81827.1 - 3.7e-182 605.7 0.1 4.2e-182 605.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM81827.1 - 0.044 12.5 0.0 0.08 11.6 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) SKG6 PF08693.5 EIM81828.1 - 0.00014 21.0 0.1 0.00027 20.1 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain UPF0203 PF05254.7 EIM81829.1 - 7.8e-19 67.3 3.6 5.4e-18 64.5 2.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EIM81829.1 - 0.053 13.4 2.5 2.5 8.1 0.3 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EIM81829.1 - 0.16 11.9 6.5 3.9 7.5 0.1 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Metallophos_2 PF12850.2 EIM81830.1 - 3.6e-21 75.6 0.2 4.8e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIM81830.1 - 7e-06 25.5 1.9 0.031 13.6 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Zn_clus PF00172.13 EIM81831.1 - 7.4e-09 35.3 11.4 7.4e-09 35.3 7.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Robl_LC7 PF03259.12 EIM81833.1 - 1.9e-11 43.3 0.0 1e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Roadblock/LC7 domain Atg14 PF10186.4 EIM81834.1 - 1.4e-43 149.0 6.2 7.1e-42 143.3 4.3 2.1 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EIM81834.1 - 0.0061 15.0 2.1 0.0084 14.6 1.4 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family DASH_Spc34 PF08657.5 EIM81834.1 - 0.015 15.0 0.4 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 APG6 PF04111.7 EIM81834.1 - 0.063 12.3 0.2 0.093 11.7 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Pex14_N PF04695.8 EIM81834.1 - 1.2 9.2 9.4 9.6 6.2 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.2 EIM81835.1 - 7.2e-12 44.8 0.7 1.8e-11 43.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM81835.1 - 0.64 9.7 3.4 23 4.7 0.0 3.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) p450 PF00067.17 EIM81836.1 - 3.5e-65 220.3 0.0 4.3e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNase_PH PF01138.16 EIM81838.1 - 7.7e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIM81838.1 - 0.00041 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mago-bind PF09282.5 EIM81838.1 - 0.095 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Mago binding BTB PF00651.26 EIM81839.1 - 7.9e-15 54.8 0.8 1.3e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 BTB/POZ domain F-box-like PF12937.2 EIM81840.1 - 4e-10 39.2 0.9 1.1e-09 37.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81840.1 - 0.021 14.5 0.1 0.095 12.3 0.0 2.2 1 0 0 1 1 1 0 F-box domain Pput2613-deam PF14427.1 EIM81841.1 - 0.17 11.5 0.6 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Pput_2613-like deaminase KfrA_N PF11740.3 EIM81842.1 - 0.49 10.8 3.8 0.89 10.0 2.6 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term F-box-like PF12937.2 EIM81844.1 - 2.2e-10 40.0 1.1 4e-10 39.2 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81844.1 - 0.072 12.7 0.6 0.18 11.4 0.4 1.7 1 0 0 1 1 1 0 F-box domain O-FucT PF10250.4 EIM81846.1 - 7.3e-05 22.0 0.0 0.00019 20.6 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_76 PF03663.9 EIM81847.1 - 0.042 13.2 0.4 0.062 12.6 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Peptidase_M36 PF02128.10 EIM81848.1 - 7.2e-117 390.4 11.8 9.6e-117 389.9 8.2 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) F-box PF00646.28 EIM81849.1 - 4.6e-07 29.3 2.2 9.9e-07 28.2 1.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM81849.1 - 0.00036 20.1 1.1 0.00097 18.8 0.7 1.8 1 0 0 1 1 1 1 F-box-like CBM-like PF14683.1 EIM81850.1 - 2.5e-11 43.5 0.0 7.4e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EIM81850.1 - 6.6e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EIM81850.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.8 EIM81850.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain BTB PF00651.26 EIM81851.1 - 4.6e-07 29.8 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM81852.1 - 2.9e-06 27.2 0.0 5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DASH_Dad2 PF08654.5 EIM81852.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 SMC_N PF02463.14 EIM81853.1 - 1.4e-21 76.7 0.0 2.2e-21 76.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIM81853.1 - 1.3e-12 48.4 20.4 1.3e-12 48.4 14.1 5.9 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EIM81853.1 - 0.00022 21.2 0.3 0.00022 21.2 0.2 3.4 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EIM81853.1 - 0.00036 19.9 0.0 0.00092 18.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EIM81853.1 - 0.014 15.6 0.1 0.35 11.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM81853.1 - 0.49 11.2 0.0 0.49 11.2 0.0 4.9 5 1 0 5 5 5 0 AAA domain G-alpha PF00503.15 EIM81854.1 - 8.5e-116 386.8 0.0 9.7e-116 386.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM81854.1 - 1.9e-12 46.7 0.2 1.2e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM81854.1 - 0.011 15.1 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EIM81854.1 - 0.013 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIM81854.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 EIM81854.1 - 0.17 10.9 0.4 12 4.9 0.0 2.3 2 0 0 2 2 2 0 AIG1 family BTB PF00651.26 EIM81855.1 - 8.3e-08 32.1 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain EHN PF06441.7 EIM81855.1 - 0.049 13.5 0.2 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus BTB PF00651.26 EIM81856.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM81857.1 - 8.4e-07 28.9 0.0 6.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Apc13p PF05839.6 EIM81857.1 - 0.055 13.4 0.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Apc13p protein Trp_DMAT PF11991.3 EIM81858.1 - 5.9e-38 131.0 0.0 6.8e-37 127.5 0.0 2.2 2 1 0 2 2 2 1 Tryptophan dimethylallyltransferase p450 PF00067.17 EIM81859.1 - 2.2e-73 247.3 0.0 2.6e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EIM81860.1 - 7.3e-67 225.6 0.0 9.9e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM81860.1 - 7.4e-28 97.6 0.1 1.3e-27 96.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM81860.1 - 0.00011 21.2 0.1 0.00017 20.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM81860.1 - 0.00064 19.7 0.4 0.0015 18.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM81860.1 - 0.0052 16.6 0.2 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM81860.1 - 0.009 14.9 0.4 0.042 12.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM81860.1 - 0.034 13.2 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EIM81860.1 - 0.055 11.9 0.1 0.081 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 EIM81860.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EIM81860.1 - 0.084 12.9 0.1 8.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM81860.1 - 0.11 11.2 0.4 0.22 10.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EIM81860.1 - 0.12 12.4 0.2 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Chs3p PF12271.3 EIM81861.1 - 2.8e-52 177.5 13.6 7.6e-52 176.0 9.4 1.6 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit CbiQ PF02361.11 EIM81863.1 - 0.048 13.2 8.2 0.085 12.4 5.7 1.4 1 1 0 1 1 1 0 Cobalt transport protein SLS PF14611.1 EIM81866.1 - 0.015 14.7 0.4 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator GPP34 PF05719.6 EIM81868.1 - 1.9e-62 210.9 0.7 2.4e-62 210.6 0.5 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF3445 PF11927.3 EIM81869.1 - 3.3e-69 233.0 0.0 4.1e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.20 EIM81872.1 - 1.8e-19 70.2 0.1 5.4e-19 68.7 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81872.1 - 6.6e-10 39.1 0.1 6.5e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81872.1 - 1.8e-09 37.4 0.2 2.6e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM81872.1 - 0.00047 20.2 0.1 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIM81872.1 - 0.0029 17.0 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EIM81872.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EIM81872.1 - 0.009 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDG PF03167.14 EIM81873.1 - 8.8e-18 64.2 0.0 5.4e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec63 PF02889.11 EIM81874.1 - 1.2e-196 652.1 0.0 3e-104 348.6 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EIM81874.1 - 2.5e-53 180.0 0.1 1.7e-29 102.5 0.1 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIM81874.1 - 1.3e-17 64.2 0.0 4.3e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIM81874.1 - 1.6e-13 50.2 0.0 1.2e-08 34.6 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIM81874.1 - 3.4e-07 30.4 0.0 0.012 15.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EIM81874.1 - 0.00015 21.1 0.0 0.011 15.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EIM81874.1 - 0.0041 16.0 0.0 0.1 11.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EIM81874.1 - 2 8.6 5.6 11 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain SET PF00856.23 EIM81875.1 - 3e-15 56.8 1.6 9.2e-15 55.3 0.2 2.3 2 1 0 2 2 2 1 SET domain CBFD_NFYB_HMF PF00808.18 EIM81876.1 - 9.9e-27 92.7 0.3 1.5e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIM81876.1 - 4.2e-05 23.5 0.0 6.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EIM81876.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EIM81876.1 - 0.034 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 EIM81877.1 - 4.4e-15 54.8 8.4 0.0023 17.7 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 EIM81877.1 - 3.5e-08 33.3 2.4 2.4e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 EIM81877.1 - 0.1 12.1 0.4 11 5.5 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.2 EIM81877.1 - 0.21 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 ATP_bind_1 PF03029.12 EIM81879.1 - 8.1e-74 248.1 0.0 9.7e-74 247.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EIM81879.1 - 0.086 12.7 0.5 0.78 9.7 0.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EIM81879.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.1 EIM81879.1 - 0.21 10.0 0.6 5.7 5.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_17 PF13207.1 EIM81879.1 - 4.9 8.0 7.0 1.3 9.8 1.8 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EIM81881.1 - 1.8e-15 56.8 0.0 2e-14 53.4 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM81881.1 - 3.5e-11 42.8 0.0 6.3e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM81881.1 - 0.00031 20.6 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.5 EIM81881.1 - 0.00082 19.0 0.1 0.0028 17.3 0.0 1.9 1 0 0 1 1 1 1 RQC domain SNF2_N PF00176.18 EIM81881.1 - 0.0042 15.9 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EIM81881.1 - 0.064 13.4 0.1 0.65 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain F-box-like PF12937.2 EIM81882.1 - 2.1e-05 24.1 1.3 2.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 F-box-like CPSF_A PF03178.10 EIM81883.1 - 2.2e-74 250.4 0.0 3.9e-74 249.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region GMC_oxred_N PF00732.14 EIM81885.1 - 4.9e-58 196.6 0.0 6.2e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM81885.1 - 3.3e-34 118.2 0.0 5.1e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM81885.1 - 0.0001 22.2 0.0 0.0003 20.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM81885.1 - 0.00051 19.0 0.4 0.0063 15.4 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM81885.1 - 0.00092 18.2 1.5 0.0015 17.5 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM81885.1 - 0.002 18.0 0.2 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM81885.1 - 0.0085 15.0 0.8 0.013 14.4 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIM81885.1 - 0.012 14.6 0.1 0.04 13.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EIM81885.1 - 0.038 14.0 0.3 0.22 11.5 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM81885.1 - 0.046 12.7 0.3 0.5 9.3 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM81885.1 - 0.2 10.0 1.0 0.41 9.0 0.7 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EIM81885.1 - 0.51 10.7 2.0 8.5 6.8 1.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RPE65 PF03055.10 EIM81886.1 - 1.3e-109 366.9 0.0 1.5e-109 366.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MFS_1 PF07690.11 EIM81887.1 - 6.1e-40 137.0 45.9 6.1e-40 137.0 31.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81887.1 - 5.9e-07 28.4 30.3 4.6e-05 22.1 8.6 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter ELFV_dehydrog PF00208.16 EIM81888.1 - 1.7e-76 257.0 0.7 2.2e-76 256.6 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EIM81888.1 - 1e-48 164.1 0.0 5.3e-48 161.8 0.0 2.1 2 1 1 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EIM81888.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding LTP_2 PF14368.1 EIM81889.1 - 0.56 10.3 4.3 0.13 12.3 0.8 1.5 1 1 0 1 1 1 0 Probable lipid transfer TB PF00683.12 EIM81889.1 - 1.7 8.2 5.1 15 5.2 0.4 2.4 2 0 0 2 2 2 0 TB domain IF4E PF01652.13 EIM81890.1 - 1e-48 164.9 0.0 1.5e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Epimerase PF01370.16 EIM81891.1 - 5.7e-14 52.1 0.0 1.3e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81891.1 - 5.7e-13 48.2 0.0 3e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81891.1 - 6.7e-09 36.0 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81891.1 - 0.00012 21.0 0.7 0.0037 16.2 0.5 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIM81891.1 - 0.00012 21.0 0.0 0.00047 19.1 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM81891.1 - 0.0011 18.8 0.1 0.0042 17.0 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM81891.1 - 0.0028 16.9 0.1 0.0051 16.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EIM81891.1 - 0.082 12.5 0.1 0.89 9.1 0.1 2.1 1 1 0 1 1 1 0 KR domain DUF1761 PF08570.5 EIM81893.1 - 0.05 13.6 0.7 0.05 13.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF373 PF04123.8 EIM81893.1 - 0.24 10.4 6.6 0.3 10.0 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Zn_clus PF00172.13 EIM81894.1 - 2.6e-09 36.8 9.0 3.8e-09 36.2 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EIM81898.1 - 4.8e-13 49.0 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM81898.1 - 2e-12 46.4 0.0 3.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM81898.1 - 7.3e-08 32.6 0.0 1.5e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM81898.1 - 5.1e-07 28.8 0.0 3.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EIM81898.1 - 7.6e-05 22.0 0.0 0.00028 20.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EIM81898.1 - 0.0008 19.3 0.9 0.0078 16.1 0.3 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM81898.1 - 0.024 14.2 0.6 1.2 8.7 0.4 2.3 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.1 EIM81899.1 - 1.2e-10 41.4 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM81899.1 - 4.2e-07 29.8 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM81899.1 - 1.8e-05 24.5 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM81899.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EIM81899.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.20 EIM81899.1 - 0.12 12.3 0.1 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 EIM81900.1 - 1.2e-08 35.1 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM81900.1 - 0.0036 17.0 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.2 EIM81901.1 - 1.7e-05 24.4 0.0 4.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2236 PF09995.4 EIM81903.1 - 1.4e-19 70.3 0.0 2.8e-19 69.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Sin3_corepress PF08295.7 EIM81904.1 - 5.4e-33 112.7 0.8 1.3e-32 111.5 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.16 EIM81904.1 - 9.5e-30 101.9 0.6 2.1e-13 49.6 0.0 3.7 3 1 0 3 3 3 3 Paired amphipathic helix repeat DUF4249 PF14054.1 EIM81904.1 - 0.16 11.2 0.0 0.42 9.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4249) DUF3294 PF07957.6 EIM81906.1 - 0.051 13.1 0.1 0.16 11.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3294) MFS_1 PF07690.11 EIM81907.1 - 3.8e-29 101.5 40.1 3.8e-29 101.5 27.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM81907.1 - 0.00015 20.4 8.5 0.00015 20.4 5.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1228 PF06779.9 EIM81907.1 - 0.0024 17.8 7.9 0.016 15.1 0.2 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) CheR_N PF03705.10 EIM81908.1 - 0.047 13.0 1.2 0.067 12.5 0.8 1.2 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain ADH_zinc_N PF00107.21 EIM81909.1 - 2.9e-19 68.9 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM81909.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM81909.1 - 0.002 19.0 0.0 0.0035 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HLH PF00010.21 EIM81911.1 - 8.5e-20 70.2 0.0 3.6e-19 68.1 0.0 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain PAP2 PF01569.16 EIM81915.1 - 1.1e-15 57.4 4.3 1.1e-15 57.4 3.0 3.4 2 2 2 4 4 4 1 PAP2 superfamily DUF2254 PF10011.4 EIM81915.1 - 0.069 11.6 0.3 0.13 10.6 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) p450 PF00067.17 EIM81916.1 - 3.3e-55 187.4 0.0 2.7e-52 177.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 S1-P1_nuclease PF02265.11 EIM81917.1 - 6.6e-45 153.7 0.1 2.2e-40 138.8 0.0 2.5 2 1 0 2 2 2 2 S1/P1 Nuclease AA_permease_2 PF13520.1 EIM81918.1 - 6.5e-46 156.7 49.1 8.1e-46 156.4 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM81918.1 - 7.6e-29 100.3 43.0 1e-28 99.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.13 EIM81918.1 - 0.13 11.5 1.3 0.33 10.2 0.9 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel SID-1_RNA_chan PF13965.1 EIM81918.1 - 0.88 7.6 7.1 0.07 11.2 1.3 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 bZIP_1 PF00170.16 EIM81919.1 - 1.3e-06 28.2 7.9 9e-06 25.5 5.5 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIM81919.1 - 2e-05 24.2 2.3 2e-05 24.2 1.6 2.8 2 1 1 3 3 3 2 Basic region leucine zipper TPR_MLP1_2 PF07926.7 EIM81919.1 - 0.014 15.1 1.7 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nucleoplasmin PF03066.10 EIM81919.1 - 0.21 11.1 5.5 1.3 8.4 1.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EIM81919.1 - 0.23 11.8 12.6 1.9 8.8 4.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMF_DNA_bd PF12329.3 EIM81919.1 - 3.6 7.4 6.2 0.32 10.8 0.6 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sigma70_ner PF04546.8 EIM81919.1 - 7 6.2 11.2 5.8 6.4 1.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region F-box-like PF12937.2 EIM81920.1 - 0.012 15.2 0.2 0.038 13.7 0.2 1.9 1 0 0 1 1 1 0 F-box-like AAA_12 PF13087.1 EIM81921.1 - 3.4e-43 147.3 0.0 5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM81921.1 - 1.9e-30 106.2 0.0 1.5e-16 60.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EIM81921.1 - 2.3e-12 46.9 0.0 4.1e-11 42.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM81921.1 - 3.7e-11 42.6 0.1 9.9e-11 41.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain zf-C2H2_jaz PF12171.3 EIM81921.1 - 1.3e-05 25.2 3.4 0.0042 17.1 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM81921.1 - 0.00023 21.2 8.9 0.013 15.7 0.0 4.2 3 1 0 3 3 3 1 Zinc-finger of C2H2 type UvrD-helicase PF00580.16 EIM81921.1 - 0.00037 19.8 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EIM81921.1 - 0.00044 19.5 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 EIM81921.1 - 0.0011 19.0 0.0 0.0044 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain zf-C3H1 PF10650.4 EIM81921.1 - 0.014 14.9 1.1 0.03 13.8 0.8 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain Mg_chelatase PF01078.16 EIM81921.1 - 0.026 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EIM81921.1 - 0.037 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM81921.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.1 EIM81921.1 - 0.38 10.1 0.9 4.8 6.5 0.0 2.2 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF3505 PF12013.3 EIM81921.1 - 1.9 8.7 9.4 1.9 8.7 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3505) AAA PF00004.24 EIM81922.1 - 3.5e-44 150.2 0.0 6.2e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIM81922.1 - 8.6e-09 35.5 0.0 2.3e-08 34.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIM81922.1 - 1e-06 28.5 0.0 4.8e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM81922.1 - 4.3e-06 26.8 0.4 1.5e-05 25.1 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM81922.1 - 5e-06 26.6 0.1 0.00029 20.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIM81922.1 - 0.00011 21.9 0.0 0.00032 20.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIM81922.1 - 0.00012 22.9 0.0 0.00028 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM81922.1 - 0.00015 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIM81922.1 - 0.00038 19.9 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIM81922.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIM81922.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIM81922.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM81922.1 - 0.0033 16.5 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EIM81922.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EIM81922.1 - 0.0052 16.0 0.0 0.085 12.0 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EIM81922.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIM81922.1 - 0.0069 16.6 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EIM81922.1 - 0.0082 15.3 0.1 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EIM81922.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 EIM81922.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIM81922.1 - 0.023 14.1 0.0 0.11 12.0 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain NACHT PF05729.7 EIM81922.1 - 0.026 14.1 0.0 0.6 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.1 EIM81922.1 - 0.027 13.8 0.1 0.079 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EIM81922.1 - 0.031 13.2 0.0 0.062 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 EIM81922.1 - 0.039 13.8 0.2 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 EIM81922.1 - 0.044 13.9 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EIM81922.1 - 0.047 13.7 0.0 0.22 11.5 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DivIC PF04977.10 EIM81922.1 - 0.049 13.1 0.3 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Parvo_NS1 PF01057.12 EIM81922.1 - 0.054 12.3 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EIM81922.1 - 0.099 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CorA PF01544.13 EIM81924.1 - 2.8e-11 43.0 1.9 3.8e-11 42.5 1.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2800 PF10926.3 EIM81924.1 - 0.073 12.1 0.1 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) ER_lumen_recept PF00810.13 EIM81926.1 - 2.6e-24 86.4 13.2 3.3e-24 86.0 9.1 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor TatC PF00902.13 EIM81926.1 - 0.044 13.1 10.1 0.035 13.5 5.7 1.8 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) XK-related PF09815.4 EIM81926.1 - 0.19 10.6 15.9 0.52 9.2 0.5 2.2 2 0 0 2 2 2 0 XK-related protein CTP_transf_1 PF01148.15 EIM81926.1 - 0.64 9.6 13.5 0.17 11.5 7.0 1.7 1 1 0 1 1 1 0 Cytidylyltransferase family Ninjurin PF04923.7 EIM81926.1 - 0.81 9.4 4.6 0.97 9.1 0.0 2.6 2 1 0 2 2 2 0 Ninjurin GPI2 PF06432.6 EIM81926.1 - 1.1 8.5 10.1 0.38 10.0 4.3 1.9 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase VIT1 PF01988.14 EIM81926.1 - 1.4 8.3 6.1 0.87 9.0 2.5 1.8 2 0 0 2 2 2 0 VIT family Bax1-I PF01027.15 EIM81926.1 - 4 6.9 19.0 13 5.3 13.1 1.9 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4207 PF13904.1 EIM81928.1 - 0.086 12.2 0.0 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) UNC-50 PF05216.8 EIM81930.1 - 3.5e-83 278.3 13.2 4e-83 278.1 9.1 1.0 1 0 0 1 1 1 1 UNC-50 family AA_permease_2 PF13520.1 EIM81932.1 - 8.9e-43 146.3 47.3 1e-42 146.1 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM81932.1 - 2.1e-19 69.2 40.7 3.1e-19 68.6 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.13 EIM81932.1 - 0.017 14.4 0.7 0.05 12.9 0.5 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel AA_permease_2 PF13520.1 EIM81933.1 - 1.8e-43 148.6 39.9 2.4e-43 148.2 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM81933.1 - 3.4e-25 88.3 36.2 4.6e-25 87.9 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.13 EIM81933.1 - 0.0058 15.9 1.4 0.015 14.6 1.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3112 PF11309.3 EIM81933.1 - 1.2 8.9 11.1 0.033 13.9 0.9 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3112) MtrF PF09472.5 EIM81933.1 - 1.6 8.0 4.9 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AA_permease_2 PF13520.1 EIM81934.1 - 8.8e-47 159.5 48.1 1.2e-46 159.1 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM81934.1 - 2.5e-29 101.9 39.7 3.3e-29 101.5 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease Methyltransf_16 PF10294.4 EIM81935.1 - 0.00083 18.8 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EIM81935.1 - 0.03 14.0 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM81935.1 - 0.11 12.9 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EIM81936.1 - 5.5e-43 146.7 0.1 7.8e-43 146.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1828 PF08861.5 EIM81937.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Abhydrolase_3 PF07859.8 EIM81938.1 - 7e-12 45.3 0.1 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM81938.1 - 1.1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81938.1 - 6.9e-07 29.3 0.1 1.4e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIM81938.1 - 1.1e-05 24.3 0.0 0.0002 20.2 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIM81938.1 - 1.3e-05 24.5 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EIM81938.1 - 2.2e-05 23.4 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIM81938.1 - 0.00026 19.8 0.1 0.00037 19.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EIM81938.1 - 0.027 13.9 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EIM81938.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold 3HBOH PF10605.4 EIM81938.1 - 0.14 10.2 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Abhydrolase_3 PF07859.8 EIM81939.1 - 9.5e-11 41.6 0.0 1.8e-10 40.7 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM81939.1 - 5.8e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM81939.1 - 1.5e-05 24.3 0.0 0.15 11.2 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EIM81939.1 - 0.00035 19.5 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIM81939.1 - 0.0004 20.3 0.0 0.00064 19.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIM81939.1 - 0.014 14.1 0.0 0.3 9.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Chlorophyllase PF07224.6 EIM81939.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase LIP PF03583.9 EIM81939.1 - 0.051 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase EphA2_TM PF14575.1 EIM81941.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cupredoxin_1 PF13473.1 EIM81942.1 - 7.3e-06 25.8 2.2 0.48 10.3 0.0 3.9 5 0 0 5 5 5 2 Cupredoxin-like domain DUF442 PF04273.8 EIM81942.1 - 0.022 14.6 2.3 2.9 7.7 0.0 3.5 4 0 0 4 4 4 0 Putative phosphatase (DUF442) I-set PF07679.11 EIM81942.1 - 0.14 11.9 0.1 19 5.2 0.0 3.1 4 0 0 4 4 4 0 Immunoglobulin I-set domain Uroplakin_II PF07353.7 EIM81942.1 - 6.8 6.0 8.5 14 5.0 0.0 3.4 4 0 0 4 4 4 0 Uroplakin II Oxysterol_BP PF01237.13 EIM81944.1 - 2.4e-49 167.7 0.0 5.1e-35 120.5 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein Abhydrolase_3 PF07859.8 EIM81945.1 - 8.1e-07 28.8 0.0 3.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM81945.1 - 6.6e-06 25.1 0.0 1.7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM81945.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MYEOV2 PF15004.1 EIM81945.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Myeloma-overexpressed-like p450 PF00067.17 EIM81947.1 - 7.5e-57 192.8 0.0 1.7e-56 191.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Melibiase PF02065.13 EIM81948.1 - 1.2e-35 122.9 0.1 9.5e-20 70.6 0.0 2.1 2 0 0 2 2 2 2 Melibiase Peptidase_M24 PF00557.19 EIM81949.1 - 1.5e-44 152.0 0.0 2.3e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIM81949.1 - 1.5e-24 86.9 0.0 3.1e-19 69.7 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mg_trans_NIPA PF05653.9 EIM81950.1 - 3.8e-99 331.4 9.7 4.7e-99 331.1 6.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIM81950.1 - 4.6e-06 26.8 0.9 4.6e-06 26.8 0.6 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIM81950.1 - 0.0077 16.2 4.2 0.0077 16.2 2.9 3.3 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.17 EIM81950.1 - 0.028 13.2 11.7 0.44 9.3 7.2 2.2 1 1 0 1 1 1 0 Acyltransferase family Maff2 PF12750.2 EIM81950.1 - 0.083 12.4 0.8 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Maff2 family TFIIF_alpha PF05793.7 EIM81950.1 - 0.22 9.8 6.4 0.3 9.4 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 EIM81950.1 - 0.23 10.9 4.7 0.35 10.3 3.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EIM81950.1 - 1.2 6.9 8.3 1.6 6.5 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EIM81950.1 - 1.7 9.0 8.8 3.2 8.1 6.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 EIM81950.1 - 4.2 6.5 7.9 6.3 5.9 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase_Tyr PF07714.12 EIM81951.1 - 3e-50 170.7 0.0 3.9e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM81951.1 - 9.1e-44 149.5 0.0 1.1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIM81951.1 - 0.0035 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM81951.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EIM81951.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_12 PF13087.1 EIM81952.1 - 1.4e-36 125.7 0.0 1.9e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM81952.1 - 9.1e-30 103.9 0.0 4.9e-14 52.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM81952.1 - 2.3e-12 46.4 0.0 8.4e-10 38.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIM81952.1 - 7.6e-10 38.6 0.0 2.8e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EIM81952.1 - 0.00015 21.0 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.1 EIM81952.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM81952.1 - 0.0021 18.1 0.0 0.011 15.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EIM81952.1 - 0.0036 16.7 0.0 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain ResIII PF04851.10 EIM81952.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 EIM81952.1 - 0.0093 14.9 0.0 0.33 9.8 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 EIM81952.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 EIM81952.1 - 0.033 14.3 0.0 0.08 13.1 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIM81952.1 - 0.035 13.5 0.0 0.95 8.8 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein T2SE PF00437.15 EIM81952.1 - 0.037 12.9 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EIM81952.1 - 0.046 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.9 EIM81952.1 - 0.047 13.3 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 Helicase SNF2_N PF00176.18 EIM81952.1 - 0.048 12.4 0.0 0.084 11.6 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_24 PF13479.1 EIM81952.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIM81952.1 - 0.24 10.3 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) p450 PF00067.17 EIM81953.1 - 2e-69 234.3 0.0 2.5e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Metaviral_G PF09595.5 EIM81954.1 - 0.033 13.8 1.2 0.064 12.8 0.9 1.4 1 0 0 1 1 1 0 Metaviral_G glycoprotein ER_lumen_recept PF00810.13 EIM81955.1 - 1.6e-21 77.3 5.4 1.6e-21 77.3 3.7 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor YwiC PF14256.1 EIM81955.1 - 2.6 8.1 11.4 1 9.4 1.7 2.5 1 1 1 2 2 2 0 YwiC-like protein DER1 PF04511.10 EIM81956.1 - 7e-31 107.2 0.9 9e-31 106.9 0.7 1.0 1 0 0 1 1 1 1 Der1-like family Ycf4 PF02392.11 EIM81956.1 - 0.4 9.9 2.0 0.45 9.7 0.5 1.9 1 1 0 1 1 1 0 Ycf4 Pribosyltran PF00156.22 EIM81957.1 - 1.1e-14 54.2 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIM81957.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ion_trans_2 PF07885.11 EIM81958.1 - 1.2e-29 101.7 27.9 1.6e-15 56.5 8.8 2.8 2 0 0 2 2 2 2 Ion channel Aldo_ket_red PF00248.16 EIM81959.1 - 5e-47 160.0 0.0 5.8e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3490 PF11995.3 EIM81959.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) ChAPs PF09295.5 EIM81960.1 - 2.1e-147 491.0 0.0 5.9e-147 489.5 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EIM81960.1 - 1.5e-05 25.2 0.4 0.0007 19.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM81960.1 - 0.00045 19.7 6.4 0.08 12.5 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EIM81960.1 - 0.0007 19.3 7.0 4.8 7.3 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM81960.1 - 0.0054 17.2 5.4 15 6.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM81960.1 - 0.009 15.7 0.1 0.83 9.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM81960.1 - 0.015 15.2 1.8 3.5 7.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIM81960.1 - 0.018 14.0 3.1 2.1 7.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 EIM81960.1 - 2.1 6.9 7.0 0.4 9.3 0.0 2.6 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EIM81960.1 - 2.2 9.0 7.6 8 7.2 0.0 4.5 4 1 0 5 5 5 0 Tetratricopeptide repeat DUF2046 PF09755.4 EIM81961.1 - 3e-10 39.4 7.6 3e-10 39.4 5.2 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Med15 PF09606.5 EIM81961.1 - 0.017 13.3 26.0 0.04 12.1 18.0 1.5 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MFS_1 PF07690.11 EIM81962.1 - 7.8e-20 70.8 25.6 4.6e-18 65.0 16.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2678 PF10856.3 EIM81962.1 - 0.16 11.7 2.1 0.65 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) MFS_1 PF07690.11 EIM81963.1 - 1.1e-26 93.4 32.0 1.1e-26 93.4 22.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3390 PF11870.3 EIM81963.1 - 0.075 12.9 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Glyco_hydro_3 PF00933.16 EIM81964.1 - 8e-79 264.7 0.0 1.2e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM81964.1 - 9.2e-57 192.1 0.2 2.6e-56 190.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM81964.1 - 2e-25 88.5 0.1 4.1e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIM81964.1 - 1.9e-11 43.7 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain AA_kinase PF00696.23 EIM81965.1 - 9.4e-37 126.8 0.0 1.2e-32 113.3 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 EIM81965.1 - 1.1e-09 37.5 3.2 0.00017 21.0 0.1 3.2 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EIM81965.1 - 8.5e-09 34.8 1.5 9.9e-06 24.9 0.1 2.7 3 0 0 3 3 3 2 ACT domain efb-c PF12199.3 EIM81965.1 - 0.076 12.8 0.1 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal Zn_clus PF00172.13 EIM81966.1 - 3.2e-07 30.1 12.0 4.7e-07 29.6 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.15 EIM81967.1 - 3.8e-137 457.1 0.0 2.2e-136 454.5 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM81967.1 - 9.3e-08 31.4 0.1 0.00043 19.5 0.0 2.5 3 0 0 3 3 3 2 ADP-ribosylation factor family Atrophin-1 PF03154.10 EIM81967.1 - 0.00056 18.2 3.3 0.00056 18.2 2.3 2.1 2 0 0 2 2 2 1 Atrophin-1 family AAA_29 PF13555.1 EIM81967.1 - 0.0025 17.2 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 EIM81967.1 - 0.059 12.2 0.8 0.82 8.5 0.2 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 GTP_EFTU PF00009.22 EIM81967.1 - 0.14 11.6 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain 2-Hacid_dh_C PF02826.14 EIM81968.1 - 1.8e-39 134.7 0.0 2.9e-38 130.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM81968.1 - 1.6e-25 89.1 0.0 1.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EIM81968.1 - 0.094 13.1 0.0 0.27 11.6 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_61 PF03443.9 EIM81969.1 - 4.2e-47 160.7 0.0 5.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT PF05729.7 EIM81970.1 - 1.3e-11 44.4 0.0 2.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.1 EIM81970.1 - 5.5e-06 26.1 0.6 5.5e-06 26.1 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 EIM81970.1 - 0.00031 20.8 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 EIM81970.1 - 0.00034 20.4 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_22 PF13401.1 EIM81970.1 - 0.0032 17.6 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM81970.1 - 0.029 14.1 0.0 0.088 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EIM81970.1 - 0.046 14.0 0.0 9.4 6.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EIM81970.1 - 0.076 13.2 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_6 PF13174.1 EIM81970.1 - 0.089 13.2 1.1 5.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EIM81972.1 - 2e-24 86.3 1.7 1.3e-23 83.6 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81972.1 - 6.3e-19 68.7 0.0 8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81972.1 - 7.3e-07 29.0 1.0 2.1e-06 27.5 0.7 1.6 1 1 0 1 1 1 1 KR domain DUF2247 PF10004.4 EIM81972.1 - 0.11 12.2 0.4 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Epimerase PF01370.16 EIM81972.1 - 0.2 11.0 0.6 1.1 8.6 0.4 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-RING_2 PF13639.1 EIM81973.1 - 1.8e-07 30.8 6.9 3.3e-07 30.0 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM81973.1 - 1e-05 25.5 4.4 2.1e-05 24.5 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EIM81973.1 - 1.9e-05 24.5 4.3 3.9e-05 23.5 3.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EIM81973.1 - 0.0015 18.3 2.0 0.0031 17.3 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EIM81973.1 - 0.02 14.9 6.6 0.039 13.9 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain Cnd1 PF12717.2 EIM81973.1 - 0.021 14.6 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.1 EIM81973.1 - 0.041 13.8 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BACK PF07707.10 EIM81973.1 - 0.046 13.5 0.1 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch C1_1 PF00130.17 EIM81973.1 - 0.072 12.8 4.0 0.077 12.7 2.1 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EIM81973.1 - 0.079 12.6 9.1 0.14 11.8 6.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM81973.1 - 1.4 9.0 9.2 2.8 8.0 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM81973.1 - 1.9 8.2 5.5 3.7 7.2 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EIM81973.1 - 4.3 7.4 6.7 8.3 6.5 4.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EIM81973.1 - 8.1 6.1 5.5 16 5.1 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain 2-Hacid_dh_C PF02826.14 EIM81974.1 - 1.7e-38 131.5 0.0 4.1e-37 127.0 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM81974.1 - 1.9e-27 95.3 0.0 2.3e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EIM81974.1 - 0.09 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIM81975.1 - 1.1e-26 93.7 0.2 2.1e-26 92.8 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM81975.1 - 1.1e-11 44.9 0.0 1.3e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM81975.1 - 6.8e-08 32.3 0.3 1.3e-07 31.5 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM81975.1 - 0.00036 20.0 0.1 0.00071 19.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EIM81975.1 - 0.0026 17.4 0.2 0.0064 16.1 0.1 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EIM81975.1 - 0.12 12.1 0.3 0.12 12.1 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 EIM81976.1 - 4.8e-29 99.1 8.9 1.4e-08 34.2 0.4 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat DEAD PF00270.24 EIM81977.1 - 3.5e-35 120.9 0.0 8.2e-34 116.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM81977.1 - 5.1e-19 67.9 0.7 7.5e-18 64.1 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM81977.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIM81977.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CTP_synth_N PF06418.9 EIM81978.1 - 8.6e-117 389.1 0.6 1.1e-116 388.7 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EIM81978.1 - 6.4e-50 169.2 0.0 9.9e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIM81978.1 - 0.00043 19.7 0.0 0.0017 17.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EIM81978.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_hydro_1 PF00232.13 EIM81979.1 - 4.4e-152 506.4 3.3 5.1e-152 506.2 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EIM81979.1 - 0.034 13.5 0.1 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 EIM81979.1 - 0.052 12.3 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_18 PF00704.23 EIM81980.1 - 4.7e-60 203.8 1.9 1.2e-59 202.4 1.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_18 PF13238.1 EIM81981.1 - 9.9e-29 100.2 0.1 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM81981.1 - 2.2e-16 60.7 0.5 5.2e-16 59.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIM81981.1 - 4e-05 23.6 0.2 0.00013 21.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EIM81981.1 - 6.9e-05 23.0 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIM81981.1 - 0.00023 21.0 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EIM81981.1 - 0.00076 19.3 0.6 0.0048 16.7 0.4 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 EIM81981.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIM81981.1 - 0.0022 17.2 0.0 0.0043 16.2 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 EIM81981.1 - 0.0039 16.5 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin2 PF13189.1 EIM81981.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_19 PF13245.1 EIM81981.1 - 0.005 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ADK PF00406.17 EIM81981.1 - 0.0088 15.9 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase CoaE PF01121.15 EIM81981.1 - 0.01 15.2 0.2 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_14 PF13173.1 EIM81981.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM81981.1 - 0.027 14.4 0.3 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain dNK PF01712.14 EIM81981.1 - 0.037 13.9 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase NTPase_1 PF03266.10 EIM81981.1 - 0.045 13.4 0.8 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 EIM81981.1 - 0.049 12.5 0.0 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EIM81981.1 - 0.066 11.9 0.5 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EIM81981.1 - 0.093 13.0 0.1 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EIM81981.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIM81981.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EIM81981.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EIM81981.1 - 0.14 11.2 0.3 1 8.4 0.0 2.0 2 0 0 2 2 2 0 KaiC SRP19 PF01922.12 EIM81982.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein DUF908 PF06012.7 EIM81982.1 - 0.091 12.0 2.0 0.12 11.6 1.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pol_alpha_B_N PF08418.5 EIM81982.1 - 0.38 10.2 12.0 0.66 9.4 8.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2413 PF10310.4 EIM81982.1 - 3.8 6.2 9.2 35 3.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Pol_alpha_B_N PF08418.5 EIM81983.1 - 0.031 13.8 6.7 0.037 13.5 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal JTB PF05439.7 EIM81983.1 - 0.14 11.9 1.5 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) DUF605 PF04652.11 EIM81983.1 - 1.4 8.1 16.0 1.7 7.9 11.1 1.0 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 EIM81983.1 - 8.1 5.8 10.2 10 5.5 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 EIM81984.1 - 3.6 5.7 13.1 6 5.0 9.1 1.3 1 0 0 1 1 1 0 Transmembrane protein APH PF01636.18 EIM81986.1 - 1.5e-12 47.8 0.4 1.7e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM81986.1 - 2.1e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EIM81986.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DLH PF01738.13 EIM81987.1 - 4.4e-08 32.6 0.0 6e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family FAP PF07174.6 EIM81988.1 - 2 7.6 14.1 0.0087 15.3 3.0 1.8 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) DLH PF01738.13 EIM81993.1 - 4.5e-24 84.9 0.0 5.5e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM81993.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM81993.1 - 0.0089 15.9 0.0 1.7 8.4 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family F-box-like PF12937.2 EIM81994.1 - 0.012 15.2 0.2 0.034 13.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EIM81994.1 - 0.014 15.0 1.3 0.036 13.7 0.1 2.3 2 0 0 2 2 2 0 F-box domain zf-Sec23_Sec24 PF04810.10 EIM81995.1 - 0.032 13.7 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger F-box-like PF12937.2 EIM81996.1 - 9.2e-10 38.0 0.5 2.9e-09 36.5 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81996.1 - 0.00024 20.6 8.9 0.099 12.3 0.2 4.1 4 0 0 4 4 4 2 F-box domain LRR_7 PF13504.1 EIM81996.1 - 0.15 12.4 0.7 1.9e+02 3.0 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat SHMT PF00464.14 EIM81998.1 - 8.3e-171 567.7 0.0 9.6e-171 567.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EIM81998.1 - 0.0022 17.1 0.0 0.0056 15.8 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase F-box-like PF12937.2 EIM81999.1 - 5.4e-11 42.0 2.4 3.7e-10 39.3 1.6 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM81999.1 - 0.0063 16.1 10.9 0.33 10.6 0.2 4.6 4 1 0 4 4 4 2 F-box domain LRR_7 PF13504.1 EIM81999.1 - 1.6 9.2 5.2 84 4.0 0.0 4.9 5 1 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 EIM82000.1 - 2e-10 40.1 0.5 7.3e-10 38.4 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82000.1 - 0.01 15.4 2.8 0.5 10.0 0.1 2.9 2 0 0 2 2 2 0 F-box domain COesterase PF00135.23 EIM82001.1 - 9.9e-59 199.4 0.0 5.9e-58 196.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family DUF1749 PF08538.5 EIM82001.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.8 EIM82001.1 - 0.039 13.5 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold NAD_binding_6 PF08030.7 EIM82002.1 - 7.2e-23 81.2 0.0 1.4e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIM82002.1 - 7.1e-17 61.6 7.6 1.4e-16 60.6 5.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIM82002.1 - 7.3e-13 48.3 0.0 1.1e-11 44.4 0.0 2.8 2 1 0 2 2 2 1 FAD-binding domain Toxin_47 PF15527.1 EIM82002.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 47 YqjK PF13997.1 EIM82002.1 - 0.072 13.2 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 YqjK-like protein DLH PF01738.13 EIM82003.1 - 1.1e-16 60.7 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM82003.1 - 0.00067 19.4 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM82003.1 - 0.04 13.7 0.0 1.6 8.5 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EIM82004.1 - 2.9e-85 286.9 1.1 1e-83 281.8 0.8 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase FTR1 PF03239.9 EIM82005.1 - 8.9e-66 221.9 5.0 1.1e-65 221.6 3.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family ETRAMP PF09716.5 EIM82005.1 - 0.065 13.1 0.8 7.9 6.5 0.0 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1043 PF06295.7 EIM82005.1 - 0.31 10.7 0.7 0.75 9.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Wzy_C PF04932.10 EIM82005.1 - 1.2 8.9 9.9 0.28 10.9 0.4 2.6 2 0 0 2 2 2 0 O-Antigen ligase CoatB PF10389.4 EIM82005.1 - 1.6 8.6 6.3 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B RseC_MucC PF04246.7 EIM82005.1 - 5.4 6.5 7.6 3.7 7.1 0.9 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Cu-oxidase PF00394.17 EIM82006.1 - 2.6e-38 131.4 0.5 1.3e-34 119.3 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM82006.1 - 5.3e-35 119.6 1.2 2.9e-32 110.8 0.3 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM82006.1 - 4.2e-34 117.0 9.0 1.8e-33 114.9 0.4 3.6 3 1 0 3 3 3 1 Multicopper oxidase Peptidase_S10 PF00450.17 EIM82008.1 - 3.1e-87 293.4 3.1 3.9e-87 293.1 2.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GTP_CH_N PF12471.3 EIM82008.1 - 0.044 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Dioxygenase_C PF00775.16 EIM82009.1 - 2.6e-12 46.3 0.1 5.4e-11 42.0 0.1 2.3 1 1 0 1 1 1 1 Dioxygenase WD40 PF00400.27 EIM82010.1 - 5.7e-76 247.9 27.4 1.6e-16 59.4 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIM82010.1 - 6e-08 32.0 0.0 0.0019 17.6 0.0 5.3 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EIM82010.1 - 0.00034 19.5 0.4 10 4.7 0.1 4.7 3 2 1 4 4 4 2 Nup133 N terminal like TFIIIC_delta PF12657.2 EIM82010.1 - 0.003 17.3 5.0 0.36 10.5 0.2 3.0 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 EIM82010.1 - 0.029 14.0 0.3 1.8 8.3 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIM82010.1 - 0.21 9.3 4.2 11 3.6 0.0 3.3 3 1 2 5 5 5 0 IKI3 family BCNT PF07572.7 EIM82011.1 - 2.7e-17 62.4 2.1 2.7e-17 62.4 1.4 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Med3 PF11593.3 EIM82011.1 - 0.0022 17.3 11.9 0.0031 16.8 8.3 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Pyridox_oxidase PF01243.15 EIM82013.1 - 4.1e-05 23.4 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.16 EIM82014.1 - 1.2e-53 182.3 0.0 1.5e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIM82014.1 - 0.012 13.9 0.0 0.025 12.8 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme NAD_binding_6 PF08030.7 EIM82015.1 - 7.9e-16 58.3 0.0 2.2e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIM82015.1 - 6e-14 52.2 6.6 6e-14 52.2 4.6 2.3 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIM82015.1 - 3.5e-09 36.4 0.0 1.4e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ctf8 PF09696.5 EIM82015.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Ctf8 DUF1517 PF07466.6 EIM82015.1 - 0.22 10.4 4.1 0.095 11.6 0.7 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1517) DUF4207 PF13904.1 EIM82015.1 - 1.3 8.3 4.0 1.9 7.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) F-box-like PF12937.2 EIM82016.1 - 0.00041 20.0 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_M48 PF01435.13 EIM82016.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 DUF3486 PF11985.3 EIM82016.1 - 0.18 11.8 0.4 0.34 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) F-box PF00646.28 EIM82016.1 - 0.63 9.7 2.8 0.55 9.9 0.2 2.2 2 1 0 2 2 2 0 F-box domain Cellulase PF00150.13 EIM82017.1 - 6.1e-44 150.3 0.0 8e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PCNA_N PF00705.13 EIM82018.1 - 1.3e-49 166.9 2.6 1.9e-49 166.3 1.3 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EIM82018.1 - 2e-38 131.2 0.1 2.3e-19 69.5 0.0 2.8 3 1 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EIM82018.1 - 2.4e-07 29.8 0.1 3.3e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EIM82018.1 - 6.3e-05 22.2 0.0 0.00015 21.0 0.0 1.6 1 1 0 1 1 1 1 Rad9 Nop14 PF04147.7 EIM82018.1 - 0.035 12.0 35.2 0.041 11.8 23.3 1.9 2 0 0 2 2 2 0 Nop14-like family Hus1 PF04005.7 EIM82018.1 - 0.12 11.2 7.9 5.3 5.8 0.0 3.8 3 1 1 4 4 4 0 Hus1-like protein MIP-T3 PF10243.4 EIM82018.1 - 0.69 8.3 37.8 0.95 7.8 26.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 EIM82018.1 - 6.8 4.9 44.6 14 3.9 30.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Drc1-Sld2 PF11719.3 EIM82018.1 - 8.1 5.4 25.9 11 5.0 18.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein MFS_1 PF07690.11 EIM82019.1 - 2.5e-21 75.7 20.9 3.4e-21 75.3 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2448 PF10476.4 EIM82019.1 - 0.069 12.6 2.2 0.11 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) CDC45 PF02724.9 EIM82020.1 - 4.5e-05 21.7 9.5 5.8e-05 21.3 6.6 1.2 1 0 0 1 1 1 1 CDC45-like protein RRN3 PF05327.6 EIM82020.1 - 0.0017 16.6 8.7 0.0024 16.0 6.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EIM82020.1 - 0.0027 15.7 32.3 0.0047 14.9 22.4 1.3 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 EIM82020.1 - 0.015 14.0 2.7 0.021 13.4 1.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EIM82020.1 - 0.091 11.2 29.7 0.13 10.7 20.6 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EIM82020.1 - 1 8.6 28.5 1.4 8.1 19.7 1.2 1 0 0 1 1 1 0 SDA1 Nop25 PF09805.4 EIM82020.1 - 2 8.4 19.4 5.2 7.1 13.5 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) eIF-3c_N PF05470.7 EIM82020.1 - 4.1 5.3 14.6 6.2 4.7 10.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.7 EIM82020.1 - 4.7 5.4 27.1 6.8 4.9 18.8 1.2 1 0 0 1 1 1 0 Mpp10 protein MIP-T3 PF10243.4 EIM82020.1 - 9.5 4.5 17.8 13 4.0 12.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 EIM82022.1 - 1.5e-42 141.9 20.9 2.1e-10 40.0 0.5 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 EIM82022.1 - 2e-41 141.6 0.0 3.9e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split DUF4336 PF14234.1 EIM82023.1 - 1.8e-12 47.0 0.0 4e-08 32.7 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Ribosomal_L44 PF00935.14 EIM82024.1 - 4.2e-35 119.5 11.6 6.4e-35 119.0 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2387 PF09526.5 EIM82024.1 - 0.28 11.1 0.2 0.28 11.1 0.1 2.0 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Ank_2 PF12796.2 EIM82025.1 - 2.7e-10 40.4 0.0 2.7e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM82025.1 - 8.1e-09 34.8 0.8 4.3e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIM82025.1 - 5.9e-08 32.7 0.0 6.9e-07 29.3 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM82025.1 - 6.2e-06 25.9 0.1 0.00037 20.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EIM82025.1 - 7.9e-06 26.2 0.0 0.00037 20.9 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 EIM82025.1 - 0.00075 19.4 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM82025.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM82025.1 - 0.034 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank PF00023.25 EIM82026.1 - 8.6e-07 28.4 1.4 0.0003 20.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIM82026.1 - 4.2e-06 27.0 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIM82026.1 - 4.8e-06 26.3 0.2 0.00052 20.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EIM82026.1 - 1.2e-05 25.3 0.0 0.00034 20.7 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM82026.1 - 0.00051 20.4 0.0 0.018 15.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 EIM82026.1 - 0.0015 18.4 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM82026.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM82026.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM82027.1 - 3.2e-06 27.0 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_5 PF13857.1 EIM82027.1 - 1.1e-05 25.5 0.0 8.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EIM82027.1 - 0.00018 21.1 0.1 0.00097 18.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_7 PF13508.1 EIM82027.1 - 0.00035 20.6 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EIM82027.1 - 0.0019 18.4 0.0 0.0062 16.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM82027.1 - 0.0044 17.4 0.0 0.2 12.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Acetyltransf_9 PF13527.1 EIM82027.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_3 PF13606.1 EIM82027.1 - 0.0061 16.6 0.0 0.082 13.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Acetyltransf_10 PF13673.1 EIM82027.1 - 0.013 15.5 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM82027.1 - 0.016 15.0 0.0 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase HEAT_2 PF13646.1 EIM82028.1 - 5.7e-06 26.5 2.2 0.14 12.4 0.0 5.8 4 3 0 5 5 5 1 HEAT repeats HEAT PF02985.17 EIM82028.1 - 0.021 14.8 0.2 10 6.5 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat NARP1 PF12569.3 EIM82029.1 - 7.5e-168 559.4 3.7 4.7e-166 553.5 0.3 2.7 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EIM82029.1 - 3e-16 58.7 3.8 0.00068 19.2 1.2 7.4 6 1 0 6 6 6 4 TPR repeat TPR_16 PF13432.1 EIM82029.1 - 2.1e-07 31.4 22.5 0.061 14.0 0.0 9.4 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82029.1 - 5.6e-07 29.0 9.0 0.0079 16.0 0.0 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82029.1 - 1.2e-06 28.5 18.1 37 5.3 0.2 10.5 9 1 4 13 13 11 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82029.1 - 5e-06 26.3 0.0 14 6.2 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82029.1 - 2.6e-05 23.6 2.5 0.0051 16.3 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82029.1 - 0.00014 21.6 7.6 1.4 8.8 0.1 6.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM82029.1 - 0.00015 22.0 19.9 6.5 7.1 0.5 9.1 8 2 3 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82029.1 - 0.017 14.8 0.3 0.35 10.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PhoQ_Sensor PF08918.5 EIM82029.1 - 0.045 13.2 0.8 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 PhoQ Sensor MerR_2 PF13591.1 EIM82029.1 - 0.23 11.0 2.3 3.1 7.4 0.9 2.9 2 1 1 3 3 3 0 MerR HTH family regulatory protein TPR_7 PF13176.1 EIM82029.1 - 0.35 10.7 5.3 3.9 7.5 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat GATA PF00320.22 EIM82032.1 - 4.4e-07 29.1 0.6 4.4e-07 29.1 0.4 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF457 PF04307.9 EIM82035.1 - 0.024 13.9 7.8 0.025 13.8 4.4 1.8 1 1 1 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) KH_1 PF00013.24 EIM82036.1 - 1.1e-08 34.6 0.1 4.7e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EIM82036.1 - 0.0014 18.2 1.1 0.16 11.6 0.1 2.6 2 0 0 2 2 2 2 KH domain DUF2666 PF10869.3 EIM82036.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) DUF4160 PF13711.1 EIM82036.1 - 0.017 14.9 0.3 0.044 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) K_channel_TID PF07941.6 EIM82036.1 - 0.017 15.3 6.5 0.064 13.4 4.5 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Trp_repressor PF01371.14 EIM82036.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein 3Beta_HSD PF01073.14 EIM82037.1 - 3.6e-31 107.9 0.0 3.7e-19 68.4 0.0 2.8 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM82037.1 - 7e-15 54.6 0.0 1.7e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM82037.1 - 1.3e-14 54.2 0.0 6.9e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM82037.1 - 1.1e-07 32.0 0.1 1.2e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIM82037.1 - 1.7e-05 24.8 0.0 0.0023 17.8 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EIM82037.1 - 0.001 18.7 0.0 0.008 15.8 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EIM82037.1 - 0.0011 17.9 0.0 0.021 13.6 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM82037.1 - 0.017 14.0 0.0 0.15 10.9 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 EIM82037.1 - 0.027 13.7 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family RadC PF04002.10 EIM82037.1 - 0.11 12.2 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RadC-like JAB domain Saccharop_dh PF03435.13 EIM82037.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pkinase PF00069.20 EIM82038.1 - 1.1e-65 221.4 0.0 1.1e-65 221.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82038.1 - 8.4e-32 110.2 0.9 9.2e-32 110.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 EIM82039.1 - 1.1e-17 63.1 7.0 2e-08 33.8 0.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Ank_5 PF13857.1 EIM82040.1 - 6.6e-05 23.0 0.1 0.00035 20.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EIM82040.1 - 0.0031 17.2 0.1 0.025 14.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EIM82040.1 - 0.0059 17.0 0.1 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM82040.1 - 0.013 15.7 0.0 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 EIM82040.1 - 0.06 13.6 0.0 0.32 11.3 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) FAD_binding_3 PF01494.14 EIM82041.1 - 8.8e-78 261.8 0.0 1.2e-77 261.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM82041.1 - 5.2e-26 91.2 0.0 8e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EIM82041.1 - 9e-07 28.0 3.0 1.7e-06 27.1 2.0 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM82041.1 - 2.6e-06 26.7 0.2 4.6e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIM82041.1 - 3.3e-06 25.8 1.1 4.9e-06 25.2 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIM82041.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM82041.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM82041.1 - 3.1e-05 23.9 0.4 7.2e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM82041.1 - 4e-05 22.6 0.0 6.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIM82041.1 - 0.00014 20.8 0.4 0.0002 20.3 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIM82041.1 - 0.00018 20.3 0.1 0.00026 19.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIM82041.1 - 0.00036 19.5 1.0 0.00054 18.9 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIM82041.1 - 0.0015 18.8 0.1 0.0035 17.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM82041.1 - 0.002 18.2 0.1 0.0033 17.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM82041.1 - 0.0065 16.2 0.1 0.017 14.9 0.1 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EIM82041.1 - 0.012 15.6 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EIM82041.1 - 0.02 14.4 0.4 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIM82041.1 - 0.026 14.1 0.3 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIM82041.1 - 0.053 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EIM82041.1 - 0.065 12.6 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EIM82041.1 - 0.091 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIM82041.1 - 0.097 12.4 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 EIM82042.1 - 3.7e-24 85.1 0.4 2.1e-13 49.7 0.0 3.4 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.19 EIM82042.1 - 1.4e-07 30.8 0.2 0.00015 20.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM82042.1 - 1.7e-06 27.9 0.1 5.7e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIM82042.1 - 7.9e-06 25.2 0.0 1.8e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM82042.1 - 1.8e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM82042.1 - 2.1e-05 23.7 0.1 0.00011 21.4 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIM82042.1 - 0.00025 20.0 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIM82042.1 - 0.00078 18.3 0.2 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM82042.1 - 0.00084 17.9 0.2 0.0014 17.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EIM82042.1 - 0.0024 18.2 0.0 0.095 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM82042.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EIM82042.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NACHT PF05729.7 EIM82043.1 - 3e-11 43.2 0.0 5.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM82043.1 - 3.8e-06 27.0 0.2 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM82043.1 - 0.0015 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM82043.1 - 0.014 15.1 0.0 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain TPR_10 PF13374.1 EIM82044.1 - 1.3e-44 148.8 47.9 1.7e-06 27.7 0.4 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82044.1 - 4.8e-41 138.5 33.4 2.3e-08 33.8 0.2 6.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82044.1 - 1.8e-14 52.3 4.5 1.3 9.0 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc5 PF12862.2 EIM82044.1 - 1.4e-13 50.4 13.0 0.24 11.2 0.0 8.3 1 1 4 8 8 8 4 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 EIM82044.1 - 4.6e-13 48.5 13.0 0.0082 15.7 0.1 6.3 2 2 2 6 6 6 6 TPR repeat RHH_3 PF12651.2 EIM82044.1 - 1.1e-05 25.1 0.0 6.9 6.4 0.0 6.4 8 0 0 8 8 8 1 Ribbon-helix-helix domain Rootletin PF15035.1 EIM82044.1 - 4.8e-05 23.4 9.6 0.17 11.8 0.5 3.4 2 1 1 3 3 3 2 Ciliary rootlet component, centrosome cohesion CAML PF14963.1 EIM82044.1 - 7.7e-05 22.1 2.6 13 4.9 0.0 6.1 3 1 2 6 6 6 0 Calcium signal-modulating cyclophilin ligand DUF4404 PF14357.1 EIM82044.1 - 0.00014 22.2 7.5 6.3 7.2 0.1 5.6 2 2 5 7 7 7 2 Domain of unknown function (DUF4404) TPR_8 PF13181.1 EIM82044.1 - 0.00014 21.3 0.0 34 4.5 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82044.1 - 0.00044 20.2 14.7 1.4 9.3 0.0 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat PPR_3 PF13812.1 EIM82044.1 - 0.0016 18.5 2.3 25 5.4 0.0 7.1 8 0 0 8 8 8 0 Pentatricopeptide repeat domain Ded_cyto PF06920.8 EIM82044.1 - 0.0056 16.0 0.8 13 5.0 0.0 4.7 3 2 2 6 6 6 0 Dedicator of cytokinesis MoCF_biosynth PF00994.19 EIM82044.1 - 0.11 11.8 0.1 19 4.6 0.0 3.5 2 1 0 3 3 3 0 Probable molybdopterin binding domain Synaptonemal_3 PF15191.1 EIM82044.1 - 0.14 11.9 0.1 27 4.5 0.0 3.8 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 SPOR PF05036.8 EIM82044.1 - 0.72 10.0 8.6 9.7 6.4 0.2 4.3 5 1 0 5 5 4 0 Sporulation related domain TPR_6 PF13174.1 EIM82044.1 - 1.2 9.7 8.5 7 7.3 0.0 5.7 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM82044.1 - 3.1 8.5 27.2 0.25 12.0 1.7 6.8 4 2 3 7 7 7 0 Tetratricopeptide repeat Ribosomal_S26e PF01283.14 EIM82046.1 - 4.2e-48 162.3 7.5 5e-48 162.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EIM82046.1 - 0.092 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF500 PF04366.7 EIM82047.1 - 5.3e-40 135.7 0.5 8.6e-40 135.0 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EIM82047.1 - 3.5e-15 55.1 0.1 7.5e-15 54.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM82047.1 - 1.1e-13 50.4 0.0 3.2e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM82047.1 - 8.7e-13 47.5 0.0 3.1e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-PARP PF00645.13 EIM82048.1 - 1.1e-24 86.4 0.1 1.5e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CDC27 PF09507.5 EIM82048.1 - 0.06 12.5 9.0 0.077 12.2 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VID27 PF08553.5 EIM82048.1 - 0.23 9.6 5.8 0.28 9.3 4.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TFIIF_alpha PF05793.7 EIM82048.1 - 3.6 5.8 15.0 4.9 5.4 10.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EIM82048.1 - 4 5.2 9.8 5 4.9 6.8 1.0 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EIM82049.1 - 1.5e-27 96.2 20.1 1.9e-27 95.9 14.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.14 EIM82050.1 - 1.2e-48 164.6 0.0 2.7e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIM82050.1 - 1.6e-47 160.4 0.0 2.8e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 EIM82050.1 - 3.8e-26 91.7 0.0 9.6e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIM82050.1 - 1e-22 80.1 0.0 5.9e-22 77.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EIM82050.1 - 3.3e-22 78.0 0.0 7.2e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EIM82050.1 - 2.9e-06 27.2 0.0 0.00012 21.9 0.0 2.8 2 1 0 3 3 3 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EIM82051.1 - 3.5e-31 107.6 0.0 7.6e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EIM82051.1 - 2e-23 83.3 0.1 5.3e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EIM82051.1 - 8e-20 70.5 0.0 5.4e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 EIM82051.1 - 2.1e-15 56.4 2.3 1e-11 44.7 1.4 2.5 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 EIM82051.1 - 9.7e-13 48.3 0.7 3.4e-11 43.3 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EIM82051.1 - 7.8e-11 41.4 0.0 2.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EIM82051.1 - 3e-10 39.5 0.0 6.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EIM82051.1 - 0.034 14.2 0.2 5.2 7.0 0.0 2.8 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM82051.1 - 0.22 11.2 2.2 5 6.8 0.0 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.19 EIM82052.1 - 8.1e-23 80.8 0.0 2.2e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM82052.1 - 0.00024 21.0 0.0 0.00074 19.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM82052.1 - 0.002 17.0 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM82052.1 - 0.0049 16.8 0.3 0.028 14.4 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIM82052.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EIM82052.1 - 0.03 14.7 1.3 0.058 13.8 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM82052.1 - 0.053 12.6 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EIM82052.1 - 0.11 11.9 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIM82052.1 - 0.21 10.0 4.1 0.86 7.9 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NUDIX PF00293.23 EIM82053.1 - 5.6e-12 45.4 0.3 1e-11 44.5 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain zf-C2H2_jaz PF12171.3 EIM82054.1 - 1.3e-12 47.4 20.3 0.0035 17.4 0.0 7.2 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM82054.1 - 2.1e-11 43.6 27.4 0.023 14.9 0.0 8.5 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-RING_5 PF14634.1 EIM82054.1 - 1.8e-06 27.5 13.2 1.8e-06 27.5 9.1 5.1 5 2 1 6 6 6 1 zinc-RING finger domain zf-C2H2_4 PF13894.1 EIM82054.1 - 1.8e-05 24.7 46.6 0.012 15.8 0.0 8.7 10 1 0 10 10 9 5 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 EIM82054.1 - 2.1e-05 24.1 10.9 2.1e-05 24.1 7.6 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM82054.1 - 2.1e-05 24.2 13.8 2.1e-05 24.2 9.6 4.3 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.20 EIM82054.1 - 2.4e-05 23.9 12.5 2.4e-05 23.9 8.7 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EIM82054.1 - 2.8e-05 24.1 47.5 0.016 15.4 0.1 8.9 10 0 0 10 10 8 3 Zinc finger, C2H2 type zf-C3HC4_2 PF13923.1 EIM82054.1 - 0.00019 21.3 13.9 0.00019 21.3 9.6 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.1 EIM82054.1 - 0.0006 19.6 0.2 0.0006 19.6 0.1 7.8 9 0 0 9 9 9 1 C2H2-type zinc finger zf-FCS PF06467.9 EIM82054.1 - 0.00077 19.0 0.6 0.85 9.3 0.0 3.8 3 0 0 3 3 3 1 MYM-type Zinc finger with FCS sequence motif zf-C3HC4_4 PF15227.1 EIM82054.1 - 0.064 13.1 13.0 0.35 10.7 9.0 2.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2_2 PF12756.2 EIM82054.1 - 0.88 9.7 36.7 0.095 12.8 2.2 5.6 2 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-RING_6 PF14835.1 EIM82054.1 - 5.3 6.9 12.1 0.12 12.2 3.3 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein HLH PF00010.21 EIM82055.1 - 4.5e-10 39.0 0.1 1.3e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sigma_1s PF02454.11 EIM82055.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma 1s protein HMG-CoA_red PF00368.13 EIM82056.1 - 7.8e-161 534.8 3.9 1.1e-160 534.4 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EIM82056.1 - 2.4e-15 56.3 2.7 6.4e-15 54.9 1.8 1.8 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIM82056.1 - 2.4e-06 25.7 0.9 3.8e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Patched family Disulph_isomer PF06491.6 EIM82056.1 - 0.074 12.8 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Disulphide isomerase HPIH PF13323.1 EIM82056.1 - 0.14 11.8 2.4 0.39 10.3 1.7 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif His_Phos_2 PF00328.17 EIM82057.1 - 4.1e-26 92.1 0.0 8.1e-25 87.8 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mannosyl_trans3 PF11051.3 EIM82059.1 - 1.7e-39 135.8 0.0 5.4e-39 134.1 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative F-box-like PF12937.2 EIM82060.1 - 2.3e-09 36.8 0.7 8.1e-09 35.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM82060.1 - 0.0017 17.8 0.8 6.5 6.4 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EIM82060.1 - 0.0026 17.3 0.1 0.0084 15.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain AMP-binding PF00501.23 EIM82061.1 - 1.4e-73 247.7 0.0 1.9e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM82061.1 - 3.3e-69 232.5 0.0 8.4e-69 231.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIM82061.1 - 1.9e-14 53.6 0.0 6.2e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIM82061.1 - 1e-11 44.7 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EIM82061.1 - 2e-09 38.2 0.0 6.8e-09 36.5 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EIM82061.1 - 2.3e-09 36.3 0.0 4.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EIM82061.1 - 0.0014 17.5 0.0 0.003 16.4 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Polysacc_synt_2 PF02719.10 EIM82061.1 - 0.0016 17.3 0.0 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM82061.1 - 0.0086 16.0 1.8 0.04 13.8 1.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIM82061.1 - 0.08 12.9 0.1 1.5 8.7 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding F-box-like_2 PF13013.1 EIM82062.1 - 0.00066 19.3 0.2 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 F-box-like domain Ribonuclease_T2 PF00445.13 EIM82063.1 - 2.8e-38 131.4 0.3 3.9e-38 130.9 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ADH_N PF08240.7 EIM82067.1 - 7e-33 112.6 2.8 1.2e-32 111.8 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82067.1 - 2.2e-15 56.3 0.0 3.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82067.1 - 0.0002 22.2 0.0 0.00036 21.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2338 PF10100.4 EIM82067.1 - 0.0033 15.8 0.0 0.0048 15.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2338) FAD_binding_3 PF01494.14 EIM82067.1 - 0.0034 16.4 1.0 0.0056 15.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Saccharop_dh PF03435.13 EIM82067.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Metallophos PF00149.23 EIM82068.1 - 5.4e-15 55.3 0.9 8.7e-15 54.6 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM82068.1 - 2.4e-08 33.9 0.1 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HrpB1_HrpK PF09613.5 EIM82068.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) F-box-like PF12937.2 EIM82069.1 - 0.73 9.6 3.7 0.76 9.5 0.1 2.7 3 0 0 3 3 3 0 F-box-like p450 PF00067.17 EIM82072.1 - 8.3e-46 156.4 0.0 5.5e-28 97.7 0.0 2.8 2 2 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.1 EIM82073.1 - 1.2e-14 54.0 2.9 3.3e-14 52.6 2.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family La PF05383.12 EIM82074.1 - 1.8e-14 53.2 0.0 2.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 La domain Lactamase_B_2 PF12706.2 EIM82076.1 - 5.9e-30 104.2 0.0 2.4e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EIM82076.1 - 3.8e-12 45.4 0.1 1.2e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EIM82076.1 - 6.7e-08 32.4 0.1 0.00035 20.2 0.1 3.7 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily ASL_C2 PF14698.1 EIM82076.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal G-alpha PF00503.15 EIM82077.1 - 1.4e-110 369.6 0.0 1.6e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM82077.1 - 1.7e-10 40.4 0.1 3.5e-06 26.3 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIM82077.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM82077.1 - 0.061 13.4 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM82077.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pmp3 PF01679.12 EIM82078.1 - 1.5e-18 66.2 6.7 1.8e-18 65.9 4.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PLRV_ORF5 PF01690.12 EIM82079.1 - 2 7.4 8.9 3.6 6.6 6.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AdoHcyase PF05221.12 EIM82080.1 - 1.2e-139 463.7 0.1 1.4e-139 463.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EIM82080.1 - 1.2e-83 278.8 1.0 1.8e-83 278.2 0.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIM82080.1 - 3.4e-09 36.0 0.1 6.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIM82080.1 - 0.00011 21.6 0.2 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EIM82080.1 - 0.0014 18.6 0.0 0.0041 17.0 0.0 1.9 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EIM82080.1 - 0.0079 15.8 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 EIM82080.1 - 0.065 13.3 0.2 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mitochondr_Som1 PF11093.3 EIM82081.1 - 2.3e-07 30.5 0.1 3.2e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DivIC PF04977.10 EIM82082.1 - 0.024 14.0 0.4 0.12 11.8 0.5 1.8 2 0 0 2 2 2 0 Septum formation initiator WAPL PF07814.8 EIM82083.1 - 1e-16 60.6 0.7 2.6e-14 52.7 0.1 3.5 1 1 1 2 2 2 2 Wings apart-like protein regulation of heterochromatin BIR PF00653.16 EIM82084.1 - 7.3e-34 116.0 0.5 7.7e-18 64.6 0.3 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EIM82084.1 - 8.7e-06 25.5 0.1 0.0043 16.8 0.0 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.10 EIM82084.1 - 0.03 14.0 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger Kelch_4 PF13418.1 EIM82085.1 - 0.022 14.5 0.6 2 8.2 0.1 3.4 2 1 1 3 3 3 0 Galactose oxidase, central domain Tachylectin PF14517.1 EIM82085.1 - 0.028 13.7 0.0 0.08 12.2 0.0 1.8 1 0 0 1 1 1 0 Tachylectin RAP1 PF07218.6 EIM82085.1 - 1.8 6.5 15.7 2.4 6.1 10.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.17 EIM82087.1 - 7.2e-56 189.6 0.1 9.6e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MutS_V PF00488.16 EIM82088.1 - 8.9e-96 319.8 0.1 1.4e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIM82088.1 - 1.3e-35 123.0 3.1 1.3e-35 123.0 2.1 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 EIM82088.1 - 4.6e-17 62.3 0.3 9.6e-15 54.8 0.0 3.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EIM82088.1 - 2.8e-15 56.2 0.6 2.8e-15 56.2 0.4 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EIM82088.1 - 8.1e-08 32.2 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I NTPase_1 PF03266.10 EIM82088.1 - 0.1 12.3 0.3 11 5.6 0.0 2.5 1 1 1 2 2 2 0 NTPase DEC-1_N PF04625.8 EIM82089.1 - 0.85 8.2 6.9 0.094 11.3 0.6 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Cauli_VI PF01693.11 EIM82092.1 - 0.017 15.1 0.7 0.05 13.6 0.1 1.9 2 0 0 2 2 2 0 Caulimovirus viroplasmin DUF3433 PF11915.3 EIM82094.1 - 0.014 15.5 2.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) FA_desaturase PF00487.19 EIM82095.1 - 1.1e-24 87.2 23.3 2.1e-24 86.3 16.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIM82095.1 - 0.0051 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SNF2_N PF00176.18 EIM82098.1 - 1.5e-68 230.8 2.1 1.5e-68 230.8 1.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM82098.1 - 6.5e-11 41.9 0.0 8.2e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EIM82098.1 - 1.7e-09 37.1 3.4 3.2e-09 36.3 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM82098.1 - 6.2e-09 35.5 5.4 1.2e-08 34.6 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM82098.1 - 9.8e-09 35.1 5.5 2.2e-08 33.9 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM82098.1 - 1.7e-08 33.9 6.4 3.5e-08 32.9 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM82098.1 - 1.7e-08 34.0 5.3 3.8e-08 32.9 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIM82098.1 - 9.5e-07 28.4 1.0 2.8e-06 26.9 0.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIM82098.1 - 0.00028 20.6 4.5 0.00081 19.2 3.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 EIM82098.1 - 0.0052 16.3 0.1 0.021 14.3 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase FYVE PF01363.16 EIM82098.1 - 0.006 16.4 2.1 0.015 15.1 1.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-Nse PF11789.3 EIM82098.1 - 0.27 10.7 2.8 0.76 9.3 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EIM82098.1 - 0.28 11.3 3.1 1.2 9.2 2.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EIM82098.1 - 1.3 8.6 5.4 3.2 7.4 3.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.1 EIM82098.1 - 6.8 5.5 9.3 18 4.1 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mito_carr PF00153.22 EIM82099.1 - 4.4e-58 192.9 1.2 9.8e-21 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_16 PF00722.16 EIM82100.1 - 4e-06 26.2 0.1 7.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_zinc_N PF00107.21 EIM82101.1 - 1e-17 63.9 0.0 2.3e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82101.1 - 2.7e-10 39.9 0.0 4.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM82101.1 - 0.00047 21.0 0.0 0.00086 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase APH PF01636.18 EIM82102.1 - 1.7e-14 54.1 0.0 2.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tuberin PF03542.11 EIM82102.1 - 0.014 14.4 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Tuberin MazG PF03819.12 EIM82102.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Git3 PF11710.3 EIM82103.1 - 1.4e-05 24.7 9.8 2.5e-05 23.9 6.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 LRR_4 PF12799.2 EIM82104.1 - 0.0026 17.3 1.9 1.9 8.2 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM82104.1 - 0.024 14.3 0.2 2.1 8.1 0.1 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EIM82104.1 - 0.13 12.4 0.1 19 5.7 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat DSPc PF00782.15 EIM82106.1 - 0.00034 20.1 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIM82106.1 - 0.011 16.0 0.0 0.035 14.3 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIM82106.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase TPR_11 PF13414.1 EIM82108.1 - 3.2e-15 55.5 22.6 0.012 15.2 0.1 9.0 8 2 2 10 10 10 6 TPR repeat TPR_16 PF13432.1 EIM82108.1 - 1.9e-13 50.6 25.9 0.001 19.6 0.3 9.1 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIM82108.1 - 1.2e-12 47.9 9.3 0.0021 18.3 0.1 8.0 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82108.1 - 9.3e-10 37.6 15.3 1.2 9.2 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82108.1 - 1.2e-09 37.3 5.3 0.46 10.1 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82108.1 - 5.4e-08 32.6 31.1 0.00079 19.3 0.2 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM82108.1 - 6.7e-08 31.7 11.4 0.065 13.0 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82108.1 - 2.4e-07 30.0 5.5 2.5 8.1 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat Apc3 PF12895.2 EIM82108.1 - 8e-07 29.1 15.9 0.00061 19.8 1.0 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EIM82108.1 - 2.2e-05 24.4 1.9 0.089 12.9 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82108.1 - 9.5e-05 22.7 31.3 0.83 10.4 0.2 10.7 10 1 2 12 12 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM82108.1 - 0.00013 22.1 10.4 11 6.7 0.0 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat SNAP PF14938.1 EIM82108.1 - 0.0065 15.6 6.2 0.21 10.7 0.3 2.7 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_17 PF13431.1 EIM82108.1 - 0.032 14.4 3.1 49 4.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EIM82108.1 - 0.085 13.0 4.0 2.4 8.4 0.1 3.7 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.1 EIM82108.1 - 0.38 10.7 9.2 45 4.1 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TspO_MBR PF03073.10 EIM82109.1 - 9.7e-42 141.9 9.3 1.2e-41 141.7 6.4 1.1 1 0 0 1 1 1 1 TspO/MBR family CBS PF00571.23 EIM82110.1 - 9.9e-07 28.4 0.0 0.0036 17.0 0.0 2.3 2 0 0 2 2 2 2 CBS domain DUF2034 PF10356.4 EIM82111.1 - 7.4e-26 90.4 0.2 5.9e-20 71.2 0.3 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EIM82111.1 - 1.3e-06 28.1 0.0 3.2e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease Glyco_hydro_43 PF04616.9 EIM82112.1 - 4e-42 144.2 5.3 4.6e-42 144.0 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Tyrosinase PF00264.15 EIM82113.1 - 9.8e-31 107.6 6.3 1.3e-30 107.1 4.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Mito_carr PF00153.22 EIM82114.1 - 1.3e-66 220.2 0.5 3.6e-22 77.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein G-alpha PF00503.15 EIM82115.1 - 2e-125 418.5 0.0 2.4e-125 418.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM82115.1 - 4.6e-08 32.4 0.1 5.4e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIM82115.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIM82115.1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family FA_desaturase PF00487.19 EIM82116.1 - 1.1e-14 54.5 22.9 1.1e-14 54.5 15.9 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIM82116.1 - 5.7e-13 48.4 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ADH_zinc_N PF00107.21 EIM82117.1 - 8.5e-14 51.2 0.0 1.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82117.1 - 7.2e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM82117.1 - 0.00025 21.9 0.0 0.00042 21.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM82118.1 - 3e-17 62.3 0.0 4.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82118.1 - 1.1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM82118.1 - 0.011 16.6 0.0 0.019 15.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AAA PF00004.24 EIM82119.1 - 2.9e-13 50.1 0.0 6.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM82119.1 - 9.3e-09 35.5 0.0 4.7e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM82119.1 - 3.1e-07 30.5 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 EIM82119.1 - 5.9e-06 26.0 0.0 7.9e-05 22.3 0.0 2.5 1 1 0 1 1 1 1 BAH domain AAA_19 PF13245.1 EIM82119.1 - 0.00016 21.3 0.0 0.00051 19.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EIM82119.1 - 0.00051 19.1 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EIM82119.1 - 0.0068 16.1 0.0 0.027 14.1 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_11 PF13086.1 EIM82119.1 - 0.0094 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIM82119.1 - 0.035 12.8 0.0 0.1 11.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus YL1 PF05764.8 EIM82119.1 - 1.7 8.1 23.4 0.2 11.2 9.8 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 EIM82119.1 - 7.1 4.4 19.3 0.033 12.1 6.6 1.9 2 0 0 2 2 2 0 Nop14-like family BTB PF00651.26 EIM82120.1 - 5.1e-07 29.6 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.21 EIM82121.1 - 4e-16 58.7 0.0 1.1e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82121.1 - 2.5e-07 30.4 0.0 4.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM82121.1 - 0.00012 22.9 0.0 0.00021 22.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiG_N PF11760.3 EIM82121.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal ECR1_N PF14382.1 EIM82122.1 - 1.2e-14 53.2 0.1 2.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EIM82122.1 - 0.0011 18.8 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 Lactamase_B PF00753.22 EIM82123.1 - 3e-08 33.5 0.0 4.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM82123.1 - 0.00049 19.7 0.1 0.00073 19.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2611 PF11022.3 EIM82125.1 - 5.4e-09 36.0 6.6 6.9e-08 32.4 4.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) DUF1109 PF06532.6 EIM82125.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) Abhydrolase_6 PF12697.2 EIM82126.1 - 7.3e-22 78.3 0.3 1e-21 77.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM82126.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM82127.1 - 2.3e-20 73.4 0.7 3.5e-20 72.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM82127.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM82127.1 - 0.0034 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIM82127.1 - 0.036 13.6 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Lipase3_N PF03893.11 EIM82127.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase 3 N-terminal region Abhydrolase_6 PF12697.2 EIM82128.1 - 7.6e-25 88.1 0.1 1.1e-24 87.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM82128.1 - 1.1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM82129.1 - 3.5e-23 82.6 0.1 4.7e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM82129.1 - 3.7e-08 33.2 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family HNH_2 PF13391.1 EIM82131.1 - 0.009 15.7 0.2 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease PC_rep PF01851.17 EIM82132.1 - 3.9e-19 67.7 17.9 0.00032 20.7 0.3 9.4 9 0 0 9 9 9 6 Proteasome/cyclosome repeat IBR PF01485.16 EIM82134.1 - 2.5e-14 52.9 33.5 8.5e-08 31.9 4.4 3.9 3 1 0 3 3 3 2 IBR domain RRM_1 PF00076.17 EIM82134.1 - 3e-07 29.9 0.0 1.4e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EIM82134.1 - 4.2e-07 29.5 0.4 4.2e-07 29.5 0.3 4.1 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EIM82134.1 - 1.1e-06 28.4 0.0 0.00036 20.4 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.1 EIM82134.1 - 1.7e-06 27.7 4.3 1.7e-06 27.7 3.0 3.7 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIM82134.1 - 2.6e-06 27.3 3.3 2.6e-06 27.3 2.3 4.2 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EIM82134.1 - 5.6e-05 22.9 0.0 0.0016 18.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EIM82134.1 - 0.00041 20.1 5.3 0.00041 20.1 3.7 4.3 2 1 2 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EIM82134.1 - 0.00075 19.1 5.7 0.00075 19.1 4.0 3.8 3 0 0 3 3 3 1 zinc-RING finger domain APH PF01636.18 EIM82135.1 - 5.8e-16 58.9 0.0 8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM82135.1 - 0.00045 19.8 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIM82135.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NUC153 PF08159.7 EIM82136.1 - 5.6e-13 48.2 0.2 1.3e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 NUC153 domain MOR2-PAG1_N PF14222.1 EIM82137.1 - 2.9e-130 435.5 0.0 1.2e-125 420.3 0.0 2.6 3 0 0 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EIM82137.1 - 1.6e-77 260.8 0.1 3.5e-77 259.7 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EIM82137.1 - 3.6e-16 58.0 0.6 1e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 Cell morphogenesis central region DNA_mis_repair PF01119.14 EIM82138.1 - 5.2e-27 93.6 0.3 1e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EIM82138.1 - 4.1e-13 49.1 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIM82138.1 - 6.4e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YqeY PF09424.5 EIM82138.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Yqey-like protein PBP1_TM PF14812.1 EIM82138.1 - 3.8 7.8 6.7 0.46 10.8 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RdRP PF05183.7 EIM82139.1 - 2.1e-119 399.8 0.0 2.9e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MOR2-PAG1_C PF14225.1 EIM82139.1 - 5.2e-16 59.1 0.0 1.1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RdRP PF05183.7 EIM82140.1 - 2.5e-129 432.6 0.0 3.3e-129 432.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Aldo_ket_red PF00248.16 EIM82141.1 - 4.6e-46 156.9 0.0 5.5e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DJ-1_PfpI PF01965.19 EIM82142.1 - 1.3e-25 89.5 0.0 1.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIM82142.1 - 3.3e-11 42.7 0.0 4.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EIM82142.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4139 PF13598.1 EIM82143.1 - 1.6e-61 208.3 8.9 5.7e-39 134.2 1.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EIM82143.1 - 2.2e-07 31.2 0.0 2.2e-07 31.2 0.0 3.3 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) RRM_6 PF14259.1 EIM82144.1 - 3.6e-06 26.8 0.0 8.4e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EIM82144.1 - 5e-06 26.0 3.7 8e-06 25.4 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM82144.1 - 0.00011 21.8 4.3 0.00022 20.8 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain RRM_1 PF00076.17 EIM82144.1 - 0.00035 20.1 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EIM82144.1 - 0.0039 16.8 4.8 0.0081 15.7 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EIM82144.1 - 0.0041 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EIM82144.1 - 0.02 14.7 5.3 0.04 13.7 3.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EIM82144.1 - 0.075 13.0 6.4 0.14 12.2 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SGT1 PF07093.6 EIM82145.1 - 0.0019 16.7 1.4 0.002 16.5 1.0 1.0 1 0 0 1 1 1 1 SGT1 protein DUF2457 PF10446.4 EIM82145.1 - 0.088 11.5 17.6 0.025 13.3 9.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) S-antigen PF05756.6 EIM82145.1 - 0.15 12.0 4.8 1.2 9.1 3.7 2.0 2 0 0 2 2 2 0 S-antigen protein LAT PF15234.1 EIM82145.1 - 0.16 11.3 3.6 0.23 10.9 2.5 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3381 PF11861.3 EIM82145.1 - 0.24 10.8 11.7 0.35 10.3 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RXT2_N PF08595.6 EIM82145.1 - 0.55 10.0 4.6 1.1 9.0 3.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1675 PF07897.6 EIM82145.1 - 0.56 10.0 6.8 0.61 9.8 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Myc_N PF01056.13 EIM82145.1 - 4.7 6.2 6.4 6.4 5.8 4.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EIM82145.1 - 9.1 5.7 13.4 1.9 7.9 7.1 1.5 2 0 0 2 2 2 0 Nucleoplasmin Oxidored_FMN PF00724.15 EIM82147.1 - 2.1e-31 109.1 0.0 2.8e-28 98.9 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIM82148.1 - 3.3e-47 161.1 0.0 4.3e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ProRS-C_1 PF09180.6 EIM82149.1 - 7.9e-23 80.1 0.6 1.7e-22 79.0 0.4 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EIM82149.1 - 1.5e-19 70.2 0.1 2.6e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIM82149.1 - 1.2e-16 60.4 0.0 3.9e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EIM82149.1 - 2.4e-11 43.5 0.1 4.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Suppressor_APC PF11414.3 EIM82149.1 - 0.012 15.3 0.0 0.046 13.5 0.0 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein tRNA-synt_1 PF00133.17 EIM82150.1 - 2.3e-144 481.6 0.0 1.3e-143 479.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIM82150.1 - 4.7e-28 97.8 0.4 8.8e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIM82150.1 - 3.5e-21 75.3 1.6 1.2e-13 50.5 0.1 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EIM82150.1 - 2.1e-06 27.2 5.5 4.4e-06 26.1 3.8 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EIM82150.1 - 1.5e-05 24.2 0.0 0.022 13.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIM82150.1 - 0.026 13.2 0.3 0.11 11.1 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 EIM82150.1 - 0.21 10.2 4.0 9.1 4.8 0.1 3.5 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain Lactonase PF10282.4 EIM82151.1 - 6.7e-27 94.4 0.0 1.6e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller TPR_11 PF13414.1 EIM82152.1 - 5.2e-12 45.2 1.5 2.7e-09 36.5 0.4 3.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIM82152.1 - 3e-09 36.0 4.1 9.3e-07 28.2 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82152.1 - 5.1e-07 29.1 7.3 0.0031 17.3 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82152.1 - 0.00053 19.9 1.2 4.2 7.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82152.1 - 0.00054 20.3 2.5 0.45 11.3 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82152.1 - 0.0038 16.9 0.7 0.018 14.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82152.1 - 0.018 14.9 3.0 0.043 13.7 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 EIM82153.1 - 9.8e-46 154.4 1.2 3.1e-45 152.8 0.5 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIM82153.1 - 4.5e-26 91.0 0.0 9.1e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain ABC_membrane_2 PF06472.10 EIM82154.1 - 2e-82 276.4 0.6 2.8e-82 276.0 0.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIM82154.1 - 4.1e-16 59.5 0.0 7.6e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EIM82154.1 - 0.01 15.2 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIM82154.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.14 EIM82154.1 - 0.15 11.2 0.0 1.1 8.4 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3650 PF12368.3 EIM82154.1 - 2.5 7.6 4.3 0.51 9.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MatE PF01554.13 EIM82155.1 - 2.2e-45 154.1 33.8 3.3e-27 95.0 6.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EIM82155.1 - 1.5e-06 28.1 5.3 1.5e-06 28.1 3.7 4.3 3 2 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MHC2-interact PF09307.5 EIM82155.1 - 0.3 10.8 0.8 0.88 9.3 0.1 2.0 2 0 0 2 2 2 0 CLIP, MHC2 interacting AMP-binding PF00501.23 EIM82156.1 - 2.9e-87 292.7 0.0 3.6e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM82156.1 - 5.4e-10 40.0 0.0 1.6e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Snurportin1 PF11538.3 EIM82157.1 - 0.21 11.4 5.9 0.27 11.0 3.1 1.9 2 0 0 2 2 2 0 Snurportin1 Ribosomal_L16 PF00252.13 EIM82158.1 - 1.4e-34 118.6 0.1 1.8e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.5 EIM82159.1 - 2.4e-17 63.0 2.1 5.3e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EIM82160.1 - 2.7e-31 107.9 0.2 9.5e-31 106.1 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) PRP3 PF08572.5 EIM82160.1 - 7.3e-28 97.4 7.9 1.4e-27 96.5 5.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) SURF4 PF02077.10 EIM82161.1 - 9.7e-95 316.9 6.5 1.1e-94 316.7 4.5 1.0 1 0 0 1 1 1 1 SURF4 family YrhC PF14143.1 EIM82161.1 - 3.1 7.8 6.3 2.2 8.2 0.5 3.0 3 0 0 3 3 3 0 YrhC-like protein HhH-GPD PF00730.20 EIM82163.1 - 4.3e-19 68.8 0.0 1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EIM82163.1 - 1.8e-08 33.8 0.0 2e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 NUDIX domain EndIII_4Fe-2S PF10576.4 EIM82163.1 - 0.0015 18.6 6.9 0.0041 17.2 4.8 1.8 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EIM82163.1 - 0.0087 15.7 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Transaldolase PF00923.14 EIM82164.1 - 4.2e-45 154.0 0.2 5.8e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 Transaldolase SIN1 PF05422.7 EIM82166.1 - 3e-29 101.9 2.1 5.7e-17 61.4 0.2 2.3 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 EIM82166.1 - 0.0032 17.9 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.3 EIM82166.1 - 0.025 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG RBD PF02196.10 EIM82166.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF4315 PF14193.1 EIM82166.1 - 0.079 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) AAA_10 PF12846.2 EIM82170.1 - 1.5e-05 24.6 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Zot PF05707.7 EIM82170.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA PF00004.24 EIM82170.1 - 0.0042 17.2 0.3 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BTB PF00651.26 EIM82171.1 - 1.3e-07 31.6 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Herpes_ORF11 PF04797.8 EIM82172.1 - 0.03 12.7 0.1 0.033 12.6 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DDE_3 PF13358.1 EIM82174.1 - 9.8e-07 28.6 0.0 9.8e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM82175.1 - 6.9e-09 35.6 0.3 2.3e-08 33.9 0.1 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease VID27 PF08553.5 EIM82178.1 - 1.2e-37 129.6 0.0 1.4e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DEAD PF00270.24 EIM82179.1 - 1e-07 31.5 0.0 1.1e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EIM82179.1 - 0.046 12.2 0.0 0.054 12.0 0.0 1.0 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Helicase_C PF00271.26 EIM82180.1 - 7.9e-24 83.3 0.0 1.7e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM82180.1 - 0.0087 15.5 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 EIM82180.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain HTH_Tnp_Tc5 PF03221.11 EIM82181.1 - 8.4e-07 28.7 0.0 9.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EIM82182.1 - 1.2e-08 34.3 0.0 1.3e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIM82184.1 - 0.076 12.6 0.2 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain LacI PF00356.16 EIM82184.1 - 0.078 12.6 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF177 PF02620.12 EIM82186.1 - 0.16 12.0 1.6 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 FliT PF05400.8 EIM82189.1 - 0.0078 16.5 0.4 0.013 15.9 0.3 1.3 1 0 0 1 1 1 1 Flagellar protein FliT DUF1664 PF07889.7 EIM82189.1 - 0.13 12.1 0.4 0.18 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EIM82189.1 - 0.13 12.0 3.8 0.21 11.4 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EIM82189.1 - 7.9 6.4 9.0 0.26 11.2 2.0 1.8 2 1 0 2 2 2 0 FlxA-like protein BNR PF02012.15 EIM82191.1 - 1.5e-12 45.3 26.0 0.063 13.1 0.2 9.2 8 0 0 8 8 8 7 BNR/Asp-box repeat Glyco_hydro_3 PF00933.16 EIM82192.1 - 2.4e-75 253.3 0.0 3.5e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM82192.1 - 4e-51 173.7 1.1 2.7e-50 171.0 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM82192.1 - 8.6e-22 76.8 0.0 1.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain BTB PF00651.26 EIM82193.1 - 1.5e-09 37.8 0.0 3.4e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain HGD-D PF06050.8 EIM82193.1 - 0.059 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component ketoacyl-synt PF00109.21 EIM82194.1 - 3.8e-57 193.6 0.8 3.8e-57 193.6 0.6 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIM82194.1 - 1.8e-43 149.0 0.0 2.8e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EIM82194.1 - 5.7e-38 130.3 0.0 1.7e-37 128.8 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM82194.1 - 2.6e-35 121.7 0.8 1.9e-34 119.0 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EIM82194.1 - 2.3e-28 98.4 0.1 6.1e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EIM82194.1 - 1.9e-25 89.6 0.0 4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIM82194.1 - 3.1e-21 76.6 0.0 1e-20 74.9 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_23 PF13489.1 EIM82194.1 - 2.7e-11 43.4 0.0 6.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM82194.1 - 6.2e-11 42.6 0.0 1.9e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM82194.1 - 1.6e-08 35.1 0.0 1.6e-06 28.6 0.0 3.5 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM82194.1 - 3.3e-08 33.8 0.0 1.5e-07 31.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM82194.1 - 4.1e-08 32.9 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EIM82194.1 - 4.3e-07 30.1 0.1 1.4e-06 28.4 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EIM82194.1 - 0.00017 20.6 0.1 0.0006 18.8 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EIM82194.1 - 0.00086 18.9 1.9 0.024 14.2 1.3 3.2 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF938 PF06080.7 EIM82194.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Epimerase PF01370.16 EIM82194.1 - 0.0037 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM82194.1 - 0.0051 15.5 0.2 0.014 14.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 EIM82194.1 - 0.0066 16.0 0.0 0.029 13.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_24 PF13578.1 EIM82194.1 - 0.021 15.6 0.0 0.16 12.7 0.0 2.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIM82194.1 - 0.025 14.9 0.0 0.081 13.2 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIM82194.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase F-box-like PF12937.2 EIM82195.1 - 0.00033 20.3 0.2 0.002 17.8 0.1 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIM82195.1 - 0.0033 17.0 0.5 0.37 10.5 0.1 2.9 2 0 0 2 2 2 2 F-box domain zf-C2H2_jaz PF12171.3 EIM82196.1 - 0.36 11.0 8.5 0.23 11.6 2.9 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM82196.1 - 0.86 9.8 4.4 0.64 10.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GCM PF03615.10 EIM82197.1 - 1.4e-08 34.4 0.1 3.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 GCM motif protein PHD PF00628.24 EIM82197.1 - 1.1e-06 28.1 4.7 2.7e-06 26.9 3.2 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIM82197.1 - 0.0075 15.5 1.4 0.021 14.1 0.9 1.8 1 0 0 1 1 1 1 PHD-finger Peptidase_C14 PF00656.17 EIM82199.1 - 5.2e-17 62.3 0.0 5.3e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM82199.1 - 0.031 13.3 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 CHAT domain DUF1752 PF08550.5 EIM82201.1 - 1e-12 47.3 1.1 1.2e-12 47.1 0.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GMC_oxred_N PF00732.14 EIM82202.1 - 1.6e-64 217.9 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM82202.1 - 4.6e-28 98.3 0.0 8.1e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM82202.1 - 0.0065 15.4 0.1 0.0095 14.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM82202.1 - 0.023 14.6 0.2 0.081 12.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CsbD PF05532.7 EIM82205.1 - 1.1e-15 57.0 17.1 8.9e-10 38.1 2.3 2.1 1 1 1 2 2 2 2 CsbD-like DUF3659 PF12396.3 EIM82205.1 - 0.15 11.7 2.6 3.1 7.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Chitin_synth_2 PF03142.10 EIM82207.1 - 3.4e-14 52.1 0.4 3.6e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM82207.1 - 1.7e-10 40.9 5.6 2.6e-10 40.3 3.9 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM82207.1 - 1e-08 35.3 0.1 1.3e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIM82207.1 - 2.6e-05 23.5 0.1 4.4e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF3778 PF12620.3 EIM82207.1 - 0.0092 15.5 0.3 0.037 13.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3778) Glycos_transf_2 PF00535.21 EIM82207.1 - 0.012 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 GPI-anchored PF10342.4 EIM82208.1 - 8.7e-08 32.5 0.1 2.6e-07 30.9 0.0 1.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RTA1 PF04479.8 EIM82209.1 - 1.4e-13 50.8 8.4 1.5e-07 31.1 4.4 3.7 4 0 0 4 4 4 2 RTA1 like protein Abhydrolase_6 PF12697.2 EIM82210.1 - 1.9e-37 129.3 0.0 2.2e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM82210.1 - 1.7e-27 96.5 0.0 2.7e-27 95.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM82210.1 - 7.9e-21 74.3 0.0 1.1e-19 70.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM82210.1 - 1.3e-09 37.6 0.0 2.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EIM82210.1 - 1.5e-05 24.7 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 EIM82210.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EIM82210.1 - 0.0024 17.4 0.0 0.016 14.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EIM82210.1 - 0.0026 16.3 0.0 0.0057 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EIM82210.1 - 0.0037 17.0 0.0 0.0092 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EIM82210.1 - 0.006 16.2 0.0 2.5 7.6 0.0 2.1 1 1 1 2 2 2 2 Serine hydrolase Thioesterase PF00975.15 EIM82210.1 - 0.0077 16.4 0.0 0.009 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 EIM82210.1 - 0.049 12.9 0.0 0.38 10.0 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.9 EIM82210.1 - 0.093 11.1 0.0 0.14 10.5 0.0 1.5 1 1 0 1 1 1 0 Ndr family UPF0227 PF05728.7 EIM82210.1 - 0.098 12.3 0.0 4 7.1 0.0 2.7 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0227) Aldedh PF00171.17 EIM82214.1 - 2.8e-139 464.4 0.0 3.3e-139 464.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM82214.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1205 PF06722.7 EIM82214.1 - 0.06 13.5 0.1 17 5.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1205) Flavin_Reduct PF01613.13 EIM82215.1 - 1.3e-16 60.8 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Epimerase PF01370.16 EIM82216.1 - 5.8e-17 61.9 0.0 1.4e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM82216.1 - 2.5e-13 49.3 0.0 3.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM82216.1 - 1.1e-08 35.2 0.0 2.2e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM82216.1 - 1.2e-06 27.6 0.0 3.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EIM82216.1 - 6.9e-05 22.8 0.2 0.00032 20.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM82216.1 - 0.0015 17.8 0.0 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EIM82216.1 - 0.0029 17.2 0.1 0.13 11.8 0.1 2.3 1 1 0 1 1 1 1 KR domain Methyltransf_2 PF00891.13 EIM82217.1 - 1.7e-24 86.3 0.0 3.7e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIM82217.1 - 2.6e-05 23.9 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM82217.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EIM82217.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EIM82217.1 - 0.035 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EIM82217.1 - 0.036 13.1 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 EIM82217.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DOT1 PF08123.8 EIM82217.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GMC_oxred_N PF00732.14 EIM82218.1 - 2.9e-112 374.6 0.0 4.5e-61 206.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM82218.1 - 9.1e-59 197.8 0.1 1.1e-32 113.2 0.0 3.4 3 0 0 3 3 3 3 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM82218.1 - 1.2e-08 34.2 4.2 0.00022 20.2 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM82218.1 - 3.6e-06 26.9 1.6 0.013 15.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM82218.1 - 2.2e-05 24.3 7.8 0.011 15.7 0.5 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM82218.1 - 2.4e-05 23.3 8.7 0.018 13.9 1.5 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIM82218.1 - 4.2e-05 22.7 1.2 0.063 12.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 EIM82218.1 - 0.0019 18.0 0.9 0.86 9.3 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EIM82218.1 - 0.0019 16.7 5.2 0.014 13.9 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 EIM82218.1 - 0.003 16.6 4.1 0.018 14.0 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 EIM82218.1 - 0.0053 16.7 3.0 0.36 10.8 0.1 2.8 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.19 EIM82218.1 - 0.0057 15.5 17.0 0.0063 15.4 1.0 3.9 5 0 0 5 5 5 2 FAD binding domain Pyr_redox_3 PF13738.1 EIM82218.1 - 0.018 15.0 2.1 9.5 6.2 0.1 3.5 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM82218.1 - 0.3 9.8 1.3 6.6 5.4 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EIM82218.1 - 0.32 11.4 3.6 2.3 8.7 0.5 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM82218.1 - 3.9 5.9 9.2 1.4 7.4 0.4 2.9 4 0 0 4 4 4 0 Tryptophan halogenase NmrA PF05368.8 EIM82219.1 - 2.9e-14 52.8 0.0 2e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM82219.1 - 2.2e-07 31.0 0.2 3.5e-05 23.8 0.2 2.3 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM82219.1 - 2.8e-05 23.2 0.3 3.9e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIM82219.1 - 0.00036 20.5 0.4 0.00072 19.5 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EIM82219.1 - 0.00042 19.1 0.1 0.0006 18.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EIM82219.1 - 0.0026 17.8 0.2 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 EIM82219.1 - 0.0067 16.5 0.4 0.017 15.1 0.2 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain F420_oxidored PF03807.12 EIM82219.1 - 0.01 16.2 0.7 0.024 15.0 0.5 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 EIM82219.1 - 0.011 15.5 0.5 0.019 14.8 0.3 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIM82219.1 - 0.022 15.1 0.3 0.041 14.2 0.2 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIM82219.1 - 0.079 12.6 0.2 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 EIM82220.1 - 4e-69 233.3 0.0 5.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EIM82221.1 - 3.8e-22 78.2 0.2 7.2e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM82221.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.14 EIM82222.1 - 3.3e-53 180.7 0.0 4.8e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM82222.1 - 8.8e-32 110.3 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM82222.1 - 0.00026 20.0 1.1 0.0074 15.2 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM82222.1 - 0.0014 18.6 0.1 0.0043 17.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM82222.1 - 0.0031 16.4 0.4 0.01 14.7 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM82222.1 - 0.021 14.5 0.1 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIM82222.1 - 0.056 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EIM82222.1 - 0.089 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM82222.1 - 0.12 11.1 0.2 0.21 10.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EIM82222.1 - 0.13 11.2 0.2 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EIM82222.1 - 0.14 10.6 0.2 0.67 8.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Terpene_synth_C PF03936.11 EIM82223.1 - 6.5e-13 48.5 0.1 9.6e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EIM82224.1 - 3.5e-48 164.2 0.0 4.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82225.1 - 1.2e-14 53.6 0.0 1.4e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82226.1 - 3.5e-51 174.1 0.0 4.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82227.1 - 1.5e-12 46.7 0.0 1.7e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EIM82228.1 - 9.5e-14 51.0 0.5 9.5e-14 51.0 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82228.1 - 5.9e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM82228.1 - 6.1e-05 23.9 0.0 0.00013 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-UBP PF02148.14 EIM82229.1 - 0.0089 16.1 0.0 0.036 14.1 0.0 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TisB_toxin PF13939.1 EIM82229.1 - 0.37 10.5 10.1 3.3 7.5 1.1 2.7 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system SAD_SRA PF02182.12 EIM82230.1 - 4.6e-36 123.4 0.1 6.8e-36 122.9 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain BTB PF00651.26 EIM82231.1 - 4.4e-09 36.3 0.0 7.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_4 PF07993.7 EIM82232.1 - 5.7e-25 87.6 0.0 7.9e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM82232.1 - 1.5e-05 24.6 0.0 2.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIM82232.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EIM82232.1 - 0.049 13.2 0.1 0.23 11.0 0.0 2.1 3 0 0 3 3 3 0 KR domain rpo132 PF12415.3 EIM82232.1 - 0.087 11.7 0.0 0.22 10.5 0.0 1.7 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Semialdhyde_dh PF01118.19 EIM82232.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mg_trans_NIPA PF05653.9 EIM82234.1 - 5.6e-91 304.6 10.8 6.8e-91 304.3 7.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIM82234.1 - 9.5e-06 25.7 0.3 9.5e-06 25.7 0.2 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIM82234.1 - 0.0056 16.7 3.9 0.0056 16.7 2.7 3.4 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.17 EIM82234.1 - 0.028 13.2 11.0 0.82 8.4 6.9 2.4 1 1 0 1 1 1 0 Acyltransferase family Dimer_Tnp_hAT PF05699.9 EIM82236.1 - 2.6e-12 46.1 0.1 2.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIF_alpha PF05793.7 EIM82237.1 - 6.1 5.0 40.0 2 6.6 15.2 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2 PF00096.21 EIM82238.1 - 0.059 13.7 1.7 1.2 9.6 2.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pyr_redox_3 PF13738.1 EIM82240.1 - 3.2e-17 63.2 0.0 2.2e-16 60.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM82240.1 - 2.8e-11 42.9 0.0 9.8e-10 37.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIM82240.1 - 2.6e-10 39.1 0.2 1.1e-09 37.1 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIM82240.1 - 0.0035 17.2 0.0 0.42 10.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM82240.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ADH_N PF08240.7 EIM82242.1 - 6.6e-27 93.4 0.2 1e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82242.1 - 9.9e-19 67.1 0.0 2.6e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82242.1 - 0.00033 21.5 0.1 0.00071 20.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 EIM82242.1 - 0.042 13.6 0.1 3 7.6 0.1 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L12 PF00542.14 EIM82242.1 - 0.078 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Herpes_gE PF02480.11 EIM82243.1 - 0.1 10.8 0.3 0.43 8.7 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pkinase PF00069.20 EIM82244.1 - 4.9e-40 137.3 0.0 7.2e-21 74.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82244.1 - 2e-11 43.4 0.0 0.00029 19.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIM82244.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PrmA PF06325.8 EIM82244.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DBR1 PF05011.8 EIM82245.1 - 0.00035 20.4 0.1 0.00038 20.3 0.1 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Paf67 PF10255.4 EIM82245.1 - 0.1 11.4 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Ank_2 PF12796.2 EIM82246.1 - 7.5e-23 80.6 0.0 1.5e-12 47.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM82246.1 - 1.6e-11 43.3 1.1 0.00032 20.3 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.7 EIM82246.1 - 7.3e-10 38.7 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 EIM82246.1 - 1.1e-06 28.2 0.0 0.16 12.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIM82246.1 - 1.4e-06 28.3 0.6 0.00026 21.1 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM82246.1 - 2.5e-05 24.6 0.0 0.015 15.7 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 EIM82246.1 - 0.00078 19.4 0.1 0.007 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM82246.1 - 0.0025 17.9 0.2 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM82246.1 - 0.012 15.3 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 EIM82246.1 - 0.013 14.5 0.1 0.038 12.9 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIM82246.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EIM82246.1 - 0.044 12.6 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EIM82246.1 - 0.26 10.7 1.5 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family ADH_N PF08240.7 EIM82247.1 - 4.8e-25 87.4 0.9 7.5e-25 86.8 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82247.1 - 8.1e-17 60.9 0.1 1.9e-16 59.7 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82247.1 - 0.0061 17.4 0.1 0.012 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PARP PF00644.15 EIM82248.1 - 5.2e-12 45.6 0.1 6.6e-10 38.7 0.1 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RIO1 PF01163.17 EIM82249.1 - 1.6e-05 24.3 0.0 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 EIM82249.1 - 4.8e-05 22.6 0.0 5.9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EIM82249.1 - 0.021 14.5 0.2 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_C_3 PF14497.1 EIM82250.1 - 3.2e-07 30.7 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM82250.1 - 1.1e-05 25.4 0.0 0.00018 21.6 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM82250.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM82250.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DBR1 PF05011.8 EIM82251.1 - 1.4e-30 106.0 0.8 4.3e-23 81.8 0.0 2.3 1 1 1 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EIM82251.1 - 8.2e-10 38.4 0.2 1.2e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM82251.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_fiss_reg PF05308.6 EIM82251.1 - 0.03 13.6 2.2 0.061 12.6 1.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2 PF00096.21 EIM82254.1 - 5.7e-07 29.5 14.7 0.00013 22.1 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM82254.1 - 5.3e-06 26.3 9.3 0.0082 16.4 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM82254.1 - 6.6e-06 26.1 3.8 6.6e-06 26.1 2.6 2.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM82254.1 - 0.12 12.3 5.0 0.076 12.9 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger LRR_8 PF13855.1 EIM82256.1 - 0.00014 21.5 7.7 0.036 13.8 0.0 4.8 4 2 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EIM82256.1 - 0.00031 20.2 5.4 0.87 9.2 0.1 4.7 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM82256.1 - 0.0081 16.1 12.7 46 4.5 0.0 7.4 7 1 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 EIM82256.1 - 0.011 15.7 9.4 58 4.5 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat zf-CCHC_2 PF13696.1 EIM82256.1 - 0.077 12.5 0.5 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Pox_Ag35 PF03286.9 EIM82256.1 - 0.34 10.4 9.7 0.85 9.1 6.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.7 EIM82256.1 - 1.7 6.9 17.5 2.5 6.3 12.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_3_Rpc31 PF11705.3 EIM82256.1 - 1.9 8.3 16.0 3 7.7 11.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PARP PF00644.15 EIM82257.1 - 4.9e-10 39.1 0.0 7.4e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pkinase PF00069.20 EIM82258.1 - 3.3e-27 95.2 0.3 3.6e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82258.1 - 1.3e-15 57.2 0.0 1.3e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM82258.1 - 2.7e-06 26.5 0.0 3e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM82258.1 - 9.1e-05 21.6 0.1 9.6e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM82258.1 - 0.0032 17.2 0.5 0.0044 16.7 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM82258.1 - 0.0048 16.2 0.4 0.006 15.9 0.3 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIM82258.1 - 0.034 13.7 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIM82258.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Yae1_N PF09811.4 EIM82259.1 - 0.04 13.4 0.5 0.072 12.6 0.3 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF3584 PF12128.3 EIM82259.1 - 3.1 4.9 17.1 4.3 4.5 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_11 PF13414.1 EIM82260.1 - 3.3e-06 26.6 0.7 0.36 10.5 0.0 4.3 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.1 EIM82260.1 - 0.00079 19.3 9.5 0.08 12.8 0.3 5.0 6 0 0 6 6 6 3 Tetratricopeptide repeat zf-MYND PF01753.13 EIM82261.1 - 0.0024 17.6 7.5 0.0069 16.2 5.2 1.8 1 1 0 1 1 1 1 MYND finger RskA PF10099.4 EIM82261.1 - 0.063 13.0 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA YcxB PF14317.1 EIM82263.1 - 0.058 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 YcxB-like protein Pro-kuma_activ PF09286.6 EIM82265.1 - 4e-36 124.1 1.1 2.8e-23 82.5 0.1 3.0 3 1 1 4 4 4 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM82265.1 - 5.1e-10 38.9 2.8 8.6e-10 38.2 2.0 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_C30 PF05409.8 EIM82265.1 - 0.0098 14.9 0.1 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Coronavirus endopeptidase C30 Pro-kuma_activ PF09286.6 EIM82266.1 - 8e-39 132.9 0.4 6.7e-38 129.9 0.1 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM82266.1 - 1.1e-09 37.8 0.5 1.1e-09 37.8 0.4 1.9 1 1 1 2 2 2 1 Subtilase family DUF1795 PF08786.6 EIM82269.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) MFS_1 PF07690.11 EIM82270.1 - 2.8e-41 141.4 31.6 3.8e-41 140.9 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM82270.1 - 8.1e-15 54.3 14.5 1e-14 53.9 10.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 EIM82270.1 - 0.073 12.4 0.1 0.073 12.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Mcp5_PH PF12814.2 EIM82270.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology OATP PF03137.15 EIM82270.1 - 0.23 9.4 4.1 0.1 10.6 0.9 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Tmemb_cc2 PF10267.4 EIM82272.1 - 0.95 7.9 2.2 1.4 7.4 1.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein C2 PF00168.25 EIM82273.1 - 3.7e-16 58.7 0.0 6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain BTB PF00651.26 EIM82275.1 - 2.6e-06 27.4 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain AA_permease_2 PF13520.1 EIM82276.1 - 9.9e-30 103.4 46.2 3.3e-29 101.6 32.2 1.6 1 1 1 2 2 2 2 Amino acid permease BRCT PF00533.21 EIM82277.1 - 7.2e-08 32.4 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Asp PF00026.18 EIM82278.1 - 6.9e-43 147.0 0.0 9.6e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM82278.1 - 0.00063 19.7 2.0 0.014 15.3 0.9 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF4493 PF14900.1 EIM82278.1 - 0.073 12.6 0.7 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4493) Peptidase_C14 PF00656.17 EIM82279.1 - 1.1e-18 67.8 0.0 1.2e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM82279.1 - 0.0036 17.1 0.3 0.15 11.9 0.2 2.2 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain SOXp PF12336.3 EIM82279.1 - 0.03 14.9 0.0 0.87 10.2 0.0 2.2 2 0 0 2 2 2 0 SOX transcription factor CHAT PF12770.2 EIM82279.1 - 0.052 12.6 0.0 0.11 11.6 0.0 1.5 1 1 0 1 1 1 0 CHAT domain Peptidase_C13 PF01650.13 EIM82279.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase C13 family DUF4158 PF13700.1 EIM82279.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Peptidase_C14 PF00656.17 EIM82280.1 - 4.1e-22 79.0 0.0 9.6e-22 77.8 0.0 1.5 1 1 0 1 1 1 1 Caspase domain Pro-kuma_activ PF09286.6 EIM82282.1 - 1.3e-38 132.2 0.2 2e-37 128.4 0.2 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM82282.1 - 5.4e-11 42.1 1.1 5.4e-11 42.1 0.8 2.1 1 1 1 2 2 2 1 Subtilase family BTB PF00651.26 EIM82283.1 - 7.9e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Myb_DNA-bind_2 PF08914.6 EIM82284.1 - 0.00048 19.8 3.0 0.002 17.9 2.1 2.1 1 1 0 1 1 1 1 Rap1 Myb domain BRCT PF00533.21 EIM82284.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Microtub_assoc PF07989.6 EIM82285.1 - 9.7e-22 76.5 10.3 9.7e-22 76.5 7.1 10.2 8 3 2 11 11 11 2 Microtubule associated DUF4201 PF13870.1 EIM82285.1 - 0.00061 19.2 35.4 0.0011 18.4 11.0 10.0 3 2 6 9 9 9 2 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EIM82285.1 - 0.11 11.6 48.4 0.26 10.4 0.2 7.8 4 1 4 8 8 8 0 Reovirus sigma C capsid protein Filament PF00038.16 EIM82285.1 - 0.18 11.2 152.8 0.027 13.9 33.3 8.2 3 3 4 7 7 7 0 Intermediate filament protein HiaBD2 PF15403.1 EIM82285.1 - 5.4 7.2 6.7 4.3 7.5 0.9 3.2 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Myb_DNA-bind_2 PF08914.6 EIM82286.1 - 3.4e-06 26.7 4.5 1.1e-05 25.0 3.1 1.9 1 1 0 1 1 1 1 Rap1 Myb domain Omptin PF01278.15 EIM82286.1 - 0.0033 16.5 0.7 0.0049 16.0 0.5 1.2 1 0 0 1 1 1 1 Omptin family Spindle_Spc25 PF08234.7 EIM82286.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 DUF4530 PF15039.1 EIM82286.1 - 0.018 14.9 2.8 0.033 14.0 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) BRCT PF00533.21 EIM82286.1 - 0.037 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 EIM82287.1 - 2.6e-07 30.0 0.0 5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82287.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase ADH_zinc_N PF00107.21 EIM82288.1 - 1.7e-23 82.5 0.0 2.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82288.1 - 6.3e-20 72.3 0.0 1.1e-19 71.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82288.1 - 2.7e-13 49.6 0.0 5.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82289.1 - 8.2e-25 86.8 0.0 1.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82289.1 - 3e-21 76.6 0.0 5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82289.1 - 3.6e-11 42.7 0.0 7.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cyclase PF04199.8 EIM82290.1 - 9e-12 45.0 0.0 2.8e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Putative cyclase Pkinase PF00069.20 EIM82291.1 - 9.2e-47 159.3 0.0 2.4e-46 158.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82291.1 - 4.3e-23 81.7 0.0 2.2e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIM82291.1 - 0.0008 18.3 0.1 0.0012 17.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EIM82291.1 - 0.0078 15.5 1.3 0.75 9.1 0.9 2.3 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EIM82291.1 - 0.16 11.6 0.1 3.1 7.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ADH_zinc_N PF00107.21 EIM82292.1 - 1.1e-22 79.9 0.0 1.9e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82292.1 - 8e-18 65.5 0.0 1.5e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82292.1 - 2.3e-09 36.9 0.0 5.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EIM82292.1 - 0.052 13.4 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit DUF4499 PF14934.1 EIM82294.1 - 0.19 11.6 0.0 0.48 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) DUF1768 PF08719.6 EIM82297.1 - 1.7e-18 66.8 0.1 1.9e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) MFS_1 PF07690.11 EIM82299.1 - 1.6e-21 76.4 34.9 2.1e-21 76.0 24.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM82299.1 - 0.01 15.5 0.6 0.035 13.8 0.4 2.0 1 0 0 1 1 1 0 MFS_1 like family p450 PF00067.17 EIM82300.1 - 3.4e-69 233.5 0.0 4.8e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Shugoshin_C PF07557.6 EIM82302.1 - 6.7e-09 35.0 2.8 6.7e-09 35.0 1.9 4.1 6 0 0 6 6 6 1 Shugoshin C terminus Shugoshin_N PF07558.6 EIM82302.1 - 1.1e-05 25.0 2.6 1.9e-05 24.2 1.8 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF1768 PF08719.6 EIM82303.1 - 1.3e-34 119.1 0.0 3e-34 118.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) zf-HIT PF04438.11 EIM82303.1 - 0.00022 20.7 12.0 0.048 13.3 1.0 2.4 2 0 0 2 2 2 2 HIT zinc finger YyzF PF14116.1 EIM82303.1 - 0.019 14.9 1.2 1.3 9.0 0.1 2.8 2 0 0 2 2 2 0 YyzF-like protein Metallothio_Pro PF02069.11 EIM82303.1 - 0.21 11.4 7.3 2.1 8.2 0.2 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein Prim_Zn_Ribbon PF08273.7 EIM82303.1 - 0.6 10.2 8.5 0.17 12.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.2 EIM82303.1 - 1.6 8.5 12.7 1.9 8.3 2.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon BTB PF00651.26 EIM82304.1 - 2.4e-06 27.4 0.0 3.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain PsaM PF07465.8 EIM82306.1 - 0.42 10.2 3.7 0.89 9.2 2.5 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) RhoGEF PF00621.15 EIM82307.1 - 1.9e-44 151.6 0.9 2.9e-44 151.1 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 EIM82307.1 - 4.1e-19 67.9 1.4 7.2e-09 35.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIM82307.1 - 2.4e-17 62.0 0.7 3.4e-08 32.7 0.1 2.7 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 EIM82307.1 - 5.3e-15 55.0 0.0 1.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 EIM82307.1 - 7.2e-11 41.4 0.1 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 EIM82307.1 - 4.3e-10 38.8 0.7 1.2e-09 37.4 0.5 1.8 1 0 0 1 1 1 1 WH2 motif CAF-1_p150 PF11600.3 EIM82307.1 - 0.00086 18.7 33.5 0.00086 18.7 23.2 4.9 4 1 0 4 4 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal EF-hand_7 PF13499.1 EIM82307.1 - 0.0016 18.5 0.0 0.0066 16.5 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EIM82307.1 - 0.0086 15.8 0.1 7.8 6.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EIM82307.1 - 0.055 12.8 0.2 2.3 7.6 0.0 2.7 2 0 0 2 2 2 0 EF hand PH PF00169.24 EIM82307.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1720 PF08226.6 EIM82307.1 - 6.4 6.9 87.4 87 3.2 34.3 4.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) Herpes_gE PF02480.11 EIM82309.1 - 0.0027 16.0 0.0 0.0043 15.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EIM82309.1 - 0.0039 16.8 0.4 0.014 15.0 0.0 2.1 3 0 0 3 3 3 1 TMEM154 protein family DUF2970 PF11174.3 EIM82309.1 - 0.013 15.0 0.8 0.025 14.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) TMEM51 PF15345.1 EIM82309.1 - 0.014 15.1 0.4 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 RCR PF12273.3 EIM82309.1 - 0.035 14.6 0.1 0.035 14.6 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1191 PF06697.7 EIM82309.1 - 0.06 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 EIM82309.1 - 0.078 12.6 0.2 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Syndecan domain EphA2_TM PF14575.1 EIM82309.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EIM82309.1 - 0.11 11.7 0.2 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain zf-MYND PF01753.13 EIM82313.1 - 8.4e-11 41.5 17.4 4.7e-10 39.1 12.0 2.0 1 1 0 1 1 1 1 MYND finger DnaJ_CXXCXGXG PF00684.14 EIM82313.1 - 0.0091 16.0 4.3 0.02 14.9 3.0 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-Mss51 PF13824.1 EIM82313.1 - 0.31 10.9 7.6 0.74 9.7 5.3 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FtsJ PF01728.14 EIM82314.1 - 1.3e-08 35.0 0.0 2.6e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MULE PF10551.4 EIM82316.1 - 2.4e-07 30.8 0.0 5.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM82316.1 - 1.5e-06 27.5 0.1 3.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger FtsJ PF01728.14 EIM82317.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CAP_N PF01213.14 EIM82317.1 - 0.0075 15.5 0.8 0.01 15.1 0.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Gemini_C4 PF01492.12 EIM82317.1 - 0.081 12.6 0.7 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 Geminivirus C4 protein FtsJ PF01728.14 EIM82318.1 - 0.018 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase zf-MYND PF01753.13 EIM82319.1 - 5.4e-11 42.1 15.3 1.9e-10 40.4 10.6 2.0 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM82319.1 - 1 9.2 6.6 2.5 8.0 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PARP PF00644.15 EIM82320.1 - 1.7e-07 30.8 2.9 8.3e-06 25.3 2.0 3.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 EIM82320.1 - 0.018 14.7 0.3 0.018 14.7 0.2 6.0 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif Perm-CXXC PF15629.1 EIM82320.1 - 0.032 14.2 1.8 0.032 14.2 1.2 3.4 3 0 0 3 3 3 0 Permuted single zf-CXXC unit Ecl1 PF12855.2 EIM82320.1 - 0.15 11.4 0.2 0.15 11.4 0.1 4.5 4 1 0 4 4 4 0 Life-span regulatory factor DUF329 PF03884.9 EIM82321.1 - 0.047 13.2 1.4 0.047 13.2 0.9 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF329) YyzF PF14116.1 EIM82321.1 - 0.12 12.3 9.8 22 5.0 0.1 5.8 5 1 1 6 6 6 0 YyzF-like protein zf-FCS PF06467.9 EIM82321.1 - 0.16 11.6 0.3 0.16 11.6 0.2 7.6 6 3 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif zf-HIT PF04438.11 EIM82321.1 - 0.44 10.2 33.6 0.18 11.5 0.4 5.7 5 1 0 5 5 5 0 HIT zinc finger zf-MYND PF01753.13 EIM82321.1 - 0.51 10.2 26.0 9.7 6.1 0.2 5.8 4 2 0 4 4 4 0 MYND finger Endonuclease_7 PF02945.10 EIM82321.1 - 2.6 7.7 18.9 5.1 6.8 0.0 4.8 4 1 0 4 4 4 0 Recombination endonuclease VII DUF1768 PF08719.6 EIM82322.1 - 5.5e-32 110.6 0.0 6.3e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.15 EIM82323.1 - 4.3e-08 32.8 5.2 2.7e-05 23.7 0.2 3.5 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 EIM82324.1 - 7.1e-30 103.8 0.0 2.1e-29 102.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1202 PF06717.6 EIM82324.1 - 0.0019 17.5 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) DUF4112 PF13430.1 EIM82325.1 - 1e-21 76.8 2.2 1.3e-21 76.4 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) IncA PF04156.9 EIM82326.1 - 0.052 13.1 5.3 0.1 12.1 3.7 1.4 1 0 0 1 1 1 0 IncA protein Laminin_I PF06008.9 EIM82326.1 - 0.72 9.1 13.3 0.07 12.4 5.8 1.8 2 0 0 2 2 2 0 Laminin Domain I Helicase_C PF00271.26 EIM82327.1 - 1.2e-12 47.5 0.0 2.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EIM82327.1 - 4.4e-07 29.2 0.5 8.6e-07 28.2 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal DUF3489 PF11994.3 EIM82327.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) MRP-S33 PF08293.6 EIM82328.1 - 3e-20 72.0 0.2 3.7e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 BTB PF00651.26 EIM82329.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 EIM82330.1 - 7.5e-37 126.8 47.0 2.4e-35 121.9 32.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM82330.1 - 2.7e-06 26.2 12.2 2.7e-06 26.2 8.5 3.7 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EIM82330.1 - 0.00039 18.7 3.1 0.00039 18.7 2.1 2.6 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_5 PF06946.6 EIM82330.1 - 0.067 13.3 0.9 0.3 11.2 0.7 2.1 1 0 0 1 1 1 0 Phage holin AvrRpt-cleavage PF05627.6 EIM82331.1 - 0.015 14.3 0.1 0.041 12.9 0.1 1.8 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Spore_III_AF PF09581.5 EIM82331.1 - 2.6 7.8 5.6 3.4 7.5 3.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) HemY_N PF07219.8 EIM82331.1 - 8.5 5.9 9.1 1.5 8.4 0.9 2.1 1 1 1 2 2 2 0 HemY protein N-terminus CDC73 PF05179.9 EIM82332.1 - 7.7e-52 176.3 0.3 1e-51 175.8 0.2 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family dsrm PF00035.20 EIM82333.1 - 0.0019 18.7 0.0 0.017 15.6 0.0 2.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif WD40 PF00400.27 EIM82334.1 - 2.3e-10 39.9 13.4 1.6e-05 24.5 0.6 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Cript PF10235.4 EIM82334.1 - 0.2 12.0 6.5 0.59 10.5 4.5 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-Apc11 PF12861.2 EIM82334.1 - 0.54 10.1 5.9 1.5 8.7 4.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TFIIA PF03153.8 EIM82334.1 - 0.91 9.3 17.7 0.0076 16.1 5.5 2.0 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EIM82334.1 - 0.94 7.3 9.9 1.5 6.6 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family B12D PF06522.6 EIM82336.1 - 0.048 13.3 0.9 0.12 12.1 0.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit F-box-like PF12937.2 EIM82338.1 - 4.8e-10 39.0 0.8 1.3e-08 34.4 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM82338.1 - 2.4 7.9 9.1 11 5.8 0.4 3.9 3 0 0 3 3 3 0 F-box domain OPA3 PF07047.7 EIM82339.1 - 1.6e-33 115.3 0.1 2.7e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Tropomyosin PF00261.15 EIM82339.1 - 0.0043 16.1 3.8 0.0081 15.2 2.7 1.3 1 0 0 1 1 1 1 Tropomyosin Taxilin PF09728.4 EIM82339.1 - 0.015 14.4 0.8 0.026 13.6 0.6 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Matrilin_ccoil PF10393.4 EIM82339.1 - 0.016 14.5 0.1 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin IncA PF04156.9 EIM82339.1 - 0.13 11.8 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 IncA protein Zn_clus PF00172.13 EIM82340.1 - 7.5e-07 28.9 11.1 1.1e-06 28.3 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaB_2 PF07261.6 EIM82340.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment Cellulase PF00150.13 EIM82341.1 - 1.2e-09 37.7 0.0 9.3e-08 31.6 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 EIM82345.1 - 8.5e-12 44.6 0.1 3.1e-11 42.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM82345.1 - 0.11 12.1 1.0 8.4 6.1 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM82347.1 - 2.1e-11 43.3 1.1 4.8e-11 42.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82347.1 - 5.3e-07 29.1 0.9 1.3e-06 27.8 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM82348.1 - 2.1e-09 36.9 0.8 6e-09 35.4 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM82348.1 - 0.064 12.9 2.3 0.45 10.2 1.6 2.4 1 1 0 1 1 1 0 F-box domain eIF2A PF08662.6 EIM82349.1 - 1.8e-76 256.1 0.0 2.5e-75 252.4 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.1 EIM82349.1 - 0.012 15.6 3.0 0.052 13.6 2.1 2.0 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 WD40 PF00400.27 EIM82349.1 - 0.021 14.7 0.4 1.2 9.1 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat APH PF01636.18 EIM82350.1 - 7.3e-10 38.9 1.9 2.7e-08 33.8 0.9 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family F-box-like PF12937.2 EIM82351.1 - 2.2e-10 40.1 0.2 2.8e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82351.1 - 0.027 14.1 4.5 0.18 11.5 3.1 2.1 1 1 0 1 1 1 0 F-box domain APH PF01636.18 EIM82352.1 - 1.7e-12 47.5 3.5 1.6e-11 44.4 2.4 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family ADH_zinc_N PF00107.21 EIM82354.1 - 5.5e-26 90.6 0.4 1.1e-25 89.6 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82354.1 - 1.9e-18 67.5 0.0 5.7e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82354.1 - 2.6e-11 43.2 0.1 4.1e-10 39.3 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82355.1 - 9.5e-25 86.6 0.1 1.8e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82355.1 - 3e-16 60.4 0.0 6.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82355.1 - 5e-13 48.7 0.8 1e-11 44.5 0.0 3.0 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EIM82355.1 - 0.046 13.6 0.4 0.56 10.1 0.1 2.4 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit F-box-like PF12937.2 EIM82357.1 - 1.6e-08 34.0 1.3 3.7e-08 32.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM82357.1 - 0.064 12.9 3.3 1.9 8.2 2.3 2.9 1 1 0 1 1 1 0 F-box domain Pkinase PF00069.20 EIM82358.1 - 4.3e-35 121.1 0.0 1e-34 119.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82358.1 - 5.8e-12 45.2 0.0 1.2e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 EIM82358.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIF_alpha PF05793.7 EIM82358.1 - 0.46 8.7 8.7 0.89 7.8 6.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.4 EIM82358.1 - 1.1 7.7 4.8 6.2 5.3 2.1 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Glyco_hydro_31 PF01055.21 EIM82359.1 - 2.2e-157 524.3 0.8 2.8e-157 524.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM82359.1 - 1.1e-10 41.2 0.4 3.4e-10 39.6 0.3 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Mak10 PF04112.8 EIM82360.1 - 1.5e-31 108.8 0.0 2.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Serglycin PF04360.7 EIM82360.1 - 1 9.0 7.7 2.6 7.7 5.4 1.6 1 0 0 1 1 1 0 Serglycin tRNA-synt_1b PF00579.20 EIM82361.1 - 8.1e-74 248.3 0.0 9.7e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ADH_zinc_N PF00107.21 EIM82362.1 - 1.7e-27 95.5 0.0 2.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82362.1 - 4.2e-19 69.6 0.0 9.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82362.1 - 1e-12 47.7 0.0 2.4e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82363.1 - 2.4e-28 98.2 0.2 6.6e-28 96.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82363.1 - 1.3e-18 68.0 0.0 3.3e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM82363.1 - 3.1e-11 42.9 0.1 8e-10 38.4 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MgtE PF01769.11 EIM82364.1 - 8.8e-22 77.8 21.9 3e-07 30.7 0.1 3.8 4 0 0 4 4 4 3 Divalent cation transporter MscS_TM PF12794.2 EIM82364.1 - 2.7 6.4 8.5 3.8 6.0 1.9 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ada3 PF10198.4 EIM82365.1 - 1.2e-22 80.0 0.0 1.2e-22 80.0 0.0 2.1 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Sds3 PF08598.6 EIM82365.1 - 0.023 14.2 1.2 0.03 13.8 0.2 1.6 2 0 0 2 2 2 0 Sds3-like FliD_N PF02465.13 EIM82365.1 - 0.66 10.3 3.3 29 5.1 0.3 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ISG65-75 PF11727.3 EIM82365.1 - 8.8 5.2 7.0 5.7 5.9 1.1 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF3995 PF13160.1 EIM82367.1 - 0.03 14.3 13.9 0.63 10.1 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Cyto_ox_2 PF02322.10 EIM82367.1 - 0.096 11.8 12.7 0.37 9.9 4.8 2.0 2 0 0 2 2 2 0 Cytochrome oxidase subunit II VIT1 PF01988.14 EIM82367.1 - 0.29 10.6 2.2 0.52 9.7 0.2 1.9 2 0 0 2 2 2 0 VIT family RNA_polI_A34 PF08208.6 EIM82368.1 - 7.1e-09 35.6 5.8 3.6e-07 30.0 1.4 4.1 2 1 1 4 4 4 2 DNA-directed RNA polymerase I subunit RPA34.5 SOG2 PF10428.4 EIM82368.1 - 0.83 8.2 17.5 1.1 7.8 12.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4614 PF15391.1 EIM82368.1 - 8.8 6.0 25.0 14 5.4 6.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Phos_pyr_kin PF08543.7 EIM82369.1 - 3.1e-78 262.3 1.0 1.4e-56 191.4 0.0 2.4 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EIM82369.1 - 5.7e-42 143.8 0.1 8.8e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EIM82369.1 - 2.2e-08 33.6 0.3 9.4e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase FMO-like PF00743.14 EIM82371.1 - 4.2e-23 81.3 0.0 1.4e-18 66.3 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM82371.1 - 1.6e-22 80.5 0.0 2.2e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM82371.1 - 2.5e-10 39.7 0.1 1.5e-07 30.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM82371.1 - 1.8e-08 34.5 0.0 9.3e-08 32.1 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM82371.1 - 4.5e-06 26.7 0.5 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIM82371.1 - 0.00018 21.8 1.1 0.12 12.8 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EIM82371.1 - 0.00019 21.5 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_3 PF01494.14 EIM82371.1 - 0.00066 18.8 0.8 0.00084 18.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EIM82371.1 - 0.0017 17.4 0.6 0.025 13.6 0.0 2.7 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.13 EIM82371.1 - 0.002 18.1 0.2 0.075 13.0 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EIM82371.1 - 0.0023 17.1 0.1 0.28 10.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIM82371.1 - 0.0027 17.4 0.3 0.11 12.3 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIM82371.1 - 0.0039 16.8 2.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIM82371.1 - 0.0047 16.9 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM82371.1 - 0.011 14.2 0.2 0.031 12.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EIM82371.1 - 0.032 14.4 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIM82371.1 - 0.037 12.9 0.1 0.97 8.2 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM82371.1 - 0.063 12.1 0.1 0.14 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain NtA PF03146.10 EIM82371.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Agrin NtA domain AlaDh_PNT_C PF01262.16 EIM82371.1 - 0.13 11.7 2.9 0.6 9.6 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EIM82371.1 - 0.13 12.6 0.0 5.9 7.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 EIM82371.1 - 0.16 10.8 3.5 0.55 9.0 0.1 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 EIM82371.1 - 0.27 10.0 0.1 0.27 10.0 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A BaffR-Tall_bind PF09256.5 EIM82371.1 - 0.34 10.5 1.3 25 4.5 0.3 2.5 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Syntaxin-18_N PF10496.4 EIM82372.1 - 1.1e-11 44.3 0.2 1.1e-11 44.3 0.2 2.0 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EIM82372.1 - 0.0052 16.4 5.4 0.0052 16.4 3.8 2.8 3 0 0 3 3 3 1 SNARE domain F-box PF00646.28 EIM82373.1 - 2.5e-05 23.7 2.0 2.5e-05 23.7 1.4 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM82373.1 - 0.26 11.0 7.9 0.029 14.0 1.4 2.5 3 0 0 3 3 3 0 F-box-like BLVR PF06375.6 EIM82376.1 - 0.058 13.2 2.3 0.11 12.2 1.6 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Protocadherin PF08374.6 EIM82376.1 - 0.069 12.7 3.2 0.09 12.4 2.3 1.2 1 0 0 1 1 1 0 Protocadherin NST1 PF13945.1 EIM82376.1 - 4.8 7.2 8.4 1.7 8.6 4.1 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator F-box PF00646.28 EIM82377.1 - 7.6e-08 31.8 0.9 2.3e-07 30.2 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM82377.1 - 0.00034 20.2 0.7 0.0012 18.5 0.5 1.9 1 0 0 1 1 1 1 F-box-like Ribosomal_L12 PF00542.14 EIM82377.1 - 0.031 14.2 0.9 0.06 13.3 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain YopD PF05844.7 EIM82378.1 - 0.12 11.3 3.1 0.18 10.7 2.2 1.1 1 0 0 1 1 1 0 YopD protein bHLH-MYC_N PF14215.1 EIM82381.1 - 0.038 14.1 0.0 0.04 14.1 0.0 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal F-box PF00646.28 EIM82383.1 - 2.9e-10 39.5 8.8 8.9e-06 25.2 0.1 3.0 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 EIM82383.1 - 4.8e-07 29.3 12.7 0.00031 20.4 0.8 3.2 3 0 0 3 3 3 2 F-box-like AalphaY_MDB PF04611.7 EIM82383.1 - 0.021 14.7 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region DUF2102 PF09875.4 EIM82383.1 - 0.038 13.5 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) PP2C PF00481.16 EIM82384.1 - 1.8e-25 89.8 0.0 3.7e-20 72.3 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIM82384.1 - 2.6e-08 33.5 0.0 1.1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIM82384.1 - 0.00045 19.9 0.3 0.066 12.9 0.0 2.8 3 1 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Methyltransf_11 PF08241.7 EIM82385.1 - 2.6e-10 40.6 0.0 4.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM82385.1 - 4.8e-10 39.2 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM82385.1 - 7.6e-09 35.4 0.0 9.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM82385.1 - 4.8e-08 33.3 0.0 7.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM82385.1 - 2.1e-06 28.0 0.0 5.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM82385.1 - 3.3e-05 23.1 0.0 8.6e-05 21.7 0.0 1.6 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIM82385.1 - 3.9e-05 24.1 0.0 5.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIM82385.1 - 0.0071 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.6 EIM82385.1 - 0.0082 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) WHH PF14414.1 EIM82385.1 - 0.016 14.3 0.2 0.037 13.2 0.1 1.6 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH FtsJ PF01728.14 EIM82385.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EIM82385.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain IMS PF00817.15 EIM82386.1 - 2.6e-41 140.8 0.0 4.7e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIM82386.1 - 1.9e-13 50.4 0.0 4.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 EIM82386.1 - 5.3e-06 26.2 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EIM82386.1 - 0.00047 20.2 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EIM82386.1 - 0.0006 19.7 0.0 0.002 18.0 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 EIM82386.1 - 0.042 13.6 0.4 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) IMS PF00817.15 EIM82388.1 - 7e-11 42.1 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF1805 PF08827.6 EIM82388.1 - 0.075 12.8 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF1014 PF06244.7 EIM82390.1 - 3.6e-26 91.7 3.1 3.6e-26 91.7 2.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) Glycos_transf_1 PF00534.15 EIM82392.1 - 2.8e-22 78.9 0.0 3.9e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIM82392.1 - 1.5e-11 44.7 0.6 4.6e-11 43.1 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EIM82392.1 - 3.3e-08 33.4 0.0 0.0099 15.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EIM82392.1 - 0.00028 21.0 0.0 0.00058 20.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIM82392.1 - 0.00037 20.6 0.0 0.00074 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CHAT PF12770.2 EIM82393.1 - 2.7e-33 115.3 0.2 4e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EIM82393.1 - 0.00032 20.2 3.4 1.6 8.4 0.1 4.5 2 1 1 4 4 4 3 TPR repeat Peptidase_S10 PF00450.17 EIM82394.1 - 2.8e-100 336.4 10.1 3.5e-100 336.1 7.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GTP_CH_N PF12471.3 EIM82394.1 - 0.0036 16.9 0.1 0.0068 16.0 0.1 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal Abhydrolase_6 PF12697.2 EIM82394.1 - 0.021 14.6 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 EIM82395.1 - 8.7e-09 34.9 1.9 1.2e-07 31.3 0.7 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM82395.1 - 6.5e-08 32.0 0.8 6.5e-08 32.0 0.5 2.3 3 0 0 3 3 3 1 F-box domain Trypan_PARP PF05887.6 EIM82396.1 - 4.3 7.1 8.1 7.5 6.3 5.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pribosyltran_N PF13793.1 EIM82397.1 - 7e-51 170.8 0.5 1e-47 160.6 0.1 2.7 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIM82397.1 - 6e-36 123.9 1.0 3.8e-31 108.2 0.5 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIM82397.1 - 6.6e-14 51.7 0.4 9.2e-13 48.0 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIM82397.1 - 0.0007 18.8 0.1 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PS_pyruv_trans PF04230.8 EIM82397.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Pkinase PF00069.20 EIM82398.1 - 1.9e-65 220.5 0.0 2.4e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82398.1 - 2.7e-44 151.2 0.0 3.6e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM82398.1 - 0.00018 20.6 0.0 0.00082 18.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like F-box PF00646.28 EIM82399.1 - 7.3e-08 31.8 2.0 1.2e-07 31.2 0.3 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM82399.1 - 8e-06 25.4 0.4 2.8e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like IncA PF04156.9 EIM82401.1 - 0.00095 18.8 6.2 0.014 14.9 0.9 2.3 2 0 0 2 2 2 2 IncA protein Spc7 PF08317.6 EIM82401.1 - 0.015 13.9 6.9 0.025 13.2 4.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.7 EIM82401.1 - 0.046 13.4 5.6 0.2 11.3 0.5 2.5 2 0 0 2 2 2 0 Laminin Domain II V_ATPase_I PF01496.14 EIM82401.1 - 0.12 10.1 2.1 0.15 9.8 1.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD PF14073.1 EIM82401.1 - 0.29 10.9 9.4 0.56 10.0 6.5 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF1664 PF07889.7 EIM82401.1 - 0.51 10.1 3.2 1.1 9.0 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EIM82401.1 - 0.52 8.6 8.2 0.76 8.1 5.7 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EIM82401.1 - 0.55 10.0 10.8 0.16 11.7 2.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.4 EIM82401.1 - 0.59 8.8 6.1 2.4 6.8 4.3 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 COG2 PF06148.6 EIM82401.1 - 1.2 8.9 8.0 0.15 11.9 1.8 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 EIM82401.1 - 1.5 8.6 9.2 1.2 8.9 3.0 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 EIM82401.1 - 5.9 6.7 10.1 0.5 10.2 1.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Calcipressin PF04847.7 EIM82402.1 - 2.3e-38 131.6 0.0 3.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.17 EIM82402.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 EIM82403.1 - 5.8e-25 88.5 0.0 8.4e-24 84.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM82403.1 - 3.2e-16 58.6 0.0 1.1e-14 53.5 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM82403.1 - 1.8e-10 40.2 0.1 6.8e-09 35.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM82403.1 - 2.9e-09 37.0 0.0 7.1e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM82403.1 - 3e-06 27.1 0.0 0.00021 21.2 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EIM82403.1 - 1.3e-05 25.2 0.0 0.056 13.5 0.0 2.5 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EIM82403.1 - 5.6e-05 21.7 0.3 0.00034 19.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EIM82403.1 - 0.00011 21.4 0.2 0.00024 20.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIM82403.1 - 0.00082 19.7 1.4 0.27 11.6 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM82403.1 - 0.001 17.9 0.1 0.0031 16.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM82403.1 - 0.0031 16.4 0.0 0.058 12.2 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM82403.1 - 0.0054 16.5 0.1 0.26 11.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 EIM82403.1 - 0.0086 16.1 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 EIM82403.1 - 0.011 14.9 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM82403.1 - 0.017 14.6 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EIM82403.1 - 0.055 12.5 0.1 0.36 9.8 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.7 EIM82403.1 - 0.064 12.1 0.1 0.42 9.4 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EIM82403.1 - 0.19 10.5 0.1 0.83 8.4 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ENTH PF01417.15 EIM82405.1 - 2.8e-41 140.3 0.0 4.4e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIM82405.1 - 1.4e-09 37.0 0.2 2.2e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 EIM82405.1 - 5.2 6.9 11.6 0.17 11.5 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif DPBB_1 PF03330.13 EIM82407.1 - 2.4e-09 37.0 0.1 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EIM82407.1 - 0.045 13.7 0.1 0.068 13.1 0.1 1.5 1 1 0 1 1 1 0 Cerato-platanin Barwin PF00967.12 EIM82407.1 - 0.052 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Barwin family F-box-like PF12937.2 EIM82408.1 - 2.2e-06 27.2 0.5 1e-05 25.1 0.3 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM82408.1 - 0.0051 16.4 3.4 1.8 8.2 0.2 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 EIM82408.1 - 7.3 7.2 8.8 3.9 8.1 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4381 PF14316.1 EIM82409.1 - 0.013 15.6 0.8 0.022 14.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VSP PF03302.8 EIM82409.1 - 2.2 6.8 168.7 0.06 11.9 17.8 7.0 2 1 5 7 7 7 0 Giardia variant-specific surface protein hEGF PF12661.2 EIM82409.1 - 6.4 7.0 34.7 0.31 11.2 3.8 6.6 6 0 0 6 6 6 0 Human growth factor-like EGF F-box-like PF12937.2 EIM82410.1 - 1.5e-07 31.0 1.0 5.2e-07 29.2 0.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82410.1 - 1.1e-06 28.1 0.9 1.1e-06 28.1 0.6 2.3 2 0 0 2 2 2 1 F-box domain Pou PF00157.12 EIM82410.1 - 0.1 12.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Pro-kuma_activ PF09286.6 EIM82411.1 - 4.1e-38 130.6 0.4 1.9e-37 128.4 0.3 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Hist_deacetyl PF00850.14 EIM82412.1 - 2.2e-78 263.6 0.2 3.2e-78 263.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Per1 PF04080.8 EIM82413.1 - 9.3e-91 303.9 10.8 1.2e-90 303.5 7.5 1.1 1 0 0 1 1 1 1 Per1-like Glyco_hydro_12 PF01670.11 EIM82414.1 - 1.4e-32 112.6 1.4 2.4e-32 111.8 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 GPI-anchored PF10342.4 EIM82414.1 - 0.95 9.9 8.2 2 8.9 5.7 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UvrD_C_2 PF13538.1 EIM82415.1 - 5.7e-06 26.4 0.0 8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IQ PF00612.22 EIM82416.1 - 3.9 7.3 7.6 0.14 11.8 0.9 2.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif COX5B PF01215.14 EIM82418.1 - 0.047 13.3 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Peroxidase_2 PF01328.12 EIM82419.1 - 2.3e-38 131.6 0.2 2.9e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF3333 PF11812.3 EIM82419.1 - 0.11 12.4 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) AA_kinase PF00696.23 EIM82421.1 - 6.6e-41 140.4 1.3 1.1e-40 139.7 0.9 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EIM82421.1 - 1e-06 28.3 4.4 0.0063 16.2 0.1 3.2 3 1 0 3 3 3 2 PUA domain Pkinase PF00069.20 EIM82424.1 - 6.9e-31 107.3 0.0 9.7e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82424.1 - 2.4e-12 46.5 0.0 3.1e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM82424.1 - 1.1e-05 25.3 0.3 2.1e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM82424.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EIM82424.1 - 0.032 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIM82424.1 - 0.043 12.6 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EIM82424.1 - 0.073 12.0 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EIM82424.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1691 PF07950.6 EIM82425.1 - 5.2e-07 29.5 3.2 0.0002 21.2 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 EIM82425.1 - 0.038 13.8 1.8 0.063 13.1 0.1 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit E1-E2_ATPase PF00122.15 EIM82426.1 - 6.6e-61 205.2 1.5 1.2e-60 204.4 1.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIM82426.1 - 1.2e-30 107.5 0.0 2.4e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIM82426.1 - 4.7e-22 78.3 20.9 7.5e-18 64.6 1.1 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIM82426.1 - 3.5e-18 65.3 0.0 8.9e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIM82426.1 - 8.7e-14 52.1 0.1 4.1e-13 49.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIM82426.1 - 2e-12 46.3 0.0 5.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM82426.1 - 0.00015 21.4 0.5 0.027 14.0 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase adh_short PF00106.20 EIM82429.1 - 7.8e-19 68.1 0.0 1.1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM82429.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM82429.1 - 9.9e-05 22.2 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM82429.1 - 0.0031 16.9 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIM82429.1 - 0.0088 15.1 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EIM82429.1 - 0.019 14.9 0.1 0.054 13.4 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIM82429.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Colicin_V PF02674.11 EIM82430.1 - 3.3e-05 23.7 1.7 7.4e-05 22.6 1.2 1.6 1 0 0 1 1 1 1 Colicin V production protein Strabismus PF06638.6 EIM82430.1 - 3.9 5.6 5.5 5.5 5.1 3.8 1.1 1 0 0 1 1 1 0 Strabismus protein Colicin_V PF02674.11 EIM82431.1 - 0.00086 19.1 8.2 0.0014 18.5 5.7 1.4 1 1 0 1 1 1 1 Colicin V production protein DUF2157 PF09925.4 EIM82431.1 - 0.1 12.2 5.9 0.2 11.2 4.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Strabismus PF06638.6 EIM82431.1 - 8.3 4.5 6.8 11 4.2 4.7 1.1 1 0 0 1 1 1 0 Strabismus protein adh_short PF00106.20 EIM82432.1 - 3.5e-17 62.8 0.5 4.9e-17 62.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM82432.1 - 1.3e-08 34.7 0.2 2.1e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.10 EIM82432.1 - 0.0024 17.5 0.5 0.0042 16.7 0.3 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.1 EIM82432.1 - 0.0031 17.5 0.2 0.008 16.1 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM82432.1 - 0.0034 16.8 0.0 0.0086 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EIM82432.1 - 0.005 16.6 0.1 0.0076 16.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EIM82432.1 - 0.024 13.7 0.1 0.061 12.3 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EIM82432.1 - 0.038 13.6 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EIM82432.1 - 0.05 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_Gly3P_dh_N PF01210.18 EIM82432.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Helicase_RecD PF05127.9 EIM82432.1 - 0.069 12.7 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase YjeF_N PF03853.10 EIM82432.1 - 0.086 12.4 0.1 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus Ank_2 PF12796.2 EIM82434.1 - 2.4e-15 56.6 0.0 3.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM82434.1 - 2.1e-13 49.3 2.0 5.3e-06 25.9 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIM82434.1 - 1.3e-11 44.6 0.4 1.5e-05 25.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM82434.1 - 3.4e-09 36.0 0.4 0.00027 20.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIM82434.1 - 1.3e-07 31.5 0.1 1.6e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 EIM82435.1 - 3.8e-13 49.4 0.0 1.2e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIM82435.1 - 3.1e-07 30.5 0.1 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM82435.1 - 1.8e-05 24.9 0.0 0.00015 21.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIM82435.1 - 0.0004 20.6 0.0 0.0045 17.1 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIM82435.1 - 0.0013 18.8 0.3 0.033 14.3 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 EIM82435.1 - 0.013 15.4 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIM82435.1 - 0.018 14.9 0.0 0.093 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM82435.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Fzo_mitofusin PF04799.8 EIM82435.1 - 0.059 12.7 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Arch_ATPase PF01637.13 EIM82435.1 - 0.088 12.4 0.0 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 EIM82436.1 - 1.4e-15 57.2 0.0 4.3e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM82436.1 - 3.8e-15 55.5 0.0 1.6e-14 53.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM82436.1 - 0.0086 14.9 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIM82436.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ycf1 PF05758.7 EIM82437.1 - 0.014 13.2 1.7 0.013 13.2 1.2 1.0 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 EIM82437.1 - 0.058 12.8 10.6 0.073 12.5 7.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PAXNEB PF05625.6 EIM82437.1 - 0.14 10.9 1.9 0.19 10.5 1.3 1.2 1 0 0 1 1 1 0 PAXNEB protein Formyl_trans_N PF00551.14 EIM82437.1 - 0.16 11.5 1.3 0.23 10.9 0.9 1.2 1 0 0 1 1 1 0 Formyl transferase DUF2058 PF09831.4 EIM82437.1 - 2 8.2 16.9 2.9 7.7 11.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) SAPS PF04499.10 EIM82437.1 - 2.6 6.5 5.4 3.3 6.2 3.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EIM82437.1 - 2.9 5.8 8.9 3.2 5.6 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Radial_spoke_3 PF06098.6 EIM82437.1 - 6.4 5.6 16.7 10 5.0 11.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 DDRGK PF09756.4 EIM82437.1 - 8.3 5.7 28.0 14 5.0 19.4 1.3 1 0 0 1 1 1 0 DDRGK domain Piwi PF02171.12 EIM82439.1 - 2.4e-66 223.7 0.0 3.3e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIM82439.1 - 4.7e-10 38.6 0.0 1.5e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Cas_CT1975 PF09344.5 EIM82439.1 - 0.0037 16.6 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 CT1975-like protein Piwi PF02171.12 EIM82440.1 - 6.9e-73 245.2 0.0 1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIM82440.1 - 2.3e-13 49.2 0.1 7e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIM82440.1 - 2.1e-05 23.8 0.0 4.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Cerato-platanin PF07249.7 EIM82441.1 - 2.1e-45 153.5 1.1 2.4e-45 153.3 0.7 1.0 1 0 0 1 1 1 1 Cerato-platanin HMG_box PF00505.14 EIM82442.1 - 1e-11 44.8 1.0 1.9e-11 44.0 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM82442.1 - 1.9e-05 24.9 0.4 3e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain Glyoxalase_3 PF13468.1 EIM82444.1 - 1e-27 97.1 0.0 1.5e-26 93.4 0.0 2.1 1 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIM82444.1 - 0.00018 21.4 0.0 0.0045 16.9 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EIM82444.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pkinase PF00069.20 EIM82446.1 - 2.3e-48 164.6 0.0 4e-48 163.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82446.1 - 2e-25 89.3 0.0 5.7e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIM82446.1 - 0.00019 21.2 0.6 0.36 10.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM82446.1 - 0.00025 20.1 0.0 0.0047 15.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIM82446.1 - 0.00096 18.2 0.1 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RskA PF10099.4 EIM82447.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_C14 PF00656.17 EIM82449.1 - 1.9e-20 73.6 0.0 2.6e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM82449.1 - 0.00071 18.7 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 CHAT domain ABC2_membrane PF01061.19 EIM82450.1 - 7.7e-36 123.2 19.2 7.7e-36 123.2 13.3 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EIM82450.1 - 2.1e-24 86.3 0.0 3.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM82450.1 - 0.002 18.1 0.2 0.81 9.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIM82450.1 - 0.0063 15.7 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIM82450.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM82450.1 - 0.042 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIM82450.1 - 0.045 14.5 0.3 0.093 13.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM82450.1 - 0.052 13.5 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 EIM82450.1 - 0.072 12.1 29.7 0.036 13.0 18.6 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein NACHT PF05729.7 EIM82450.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EIM82450.1 - 0.16 10.6 0.1 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EIM82450.1 - 0.19 11.1 0.2 0.43 9.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIM82450.1 - 0.21 11.5 0.4 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIM82450.1 - 0.21 11.0 0.4 0.34 10.3 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Laminin_EGF PF00053.19 EIM82450.1 - 2.2 8.2 22.5 0.16 11.9 1.7 3.5 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) DPBB_1 PF03330.13 EIM82452.1 - 1.3e-08 34.6 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EIM82452.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Cerato-platanin COX17 PF05051.8 EIM82453.1 - 5.1e-20 71.2 3.8 6.2e-20 70.9 2.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 EIM82453.1 - 0.072 12.9 2.9 0.17 11.7 2.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DPBB_1 PF03330.13 EIM82454.1 - 2.1e-09 37.2 0.1 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EIM82454.1 - 0.048 13.6 0.1 0.098 12.6 0.0 1.4 1 1 0 1 1 1 0 Cerato-platanin Barwin PF00967.12 EIM82454.1 - 0.053 13.1 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Barwin family F-box-like PF12937.2 EIM82455.1 - 7.9e-08 31.9 0.1 2.3e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82455.1 - 0.022 14.3 2.4 0.068 12.8 0.0 2.9 4 0 0 4 4 4 0 F-box domain MscS_porin PF12795.2 EIM82456.1 - 0.016 14.5 8.7 0.022 14.1 6.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2353 PF09789.4 EIM82456.1 - 0.024 13.8 4.4 0.035 13.3 3.0 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) EMP24_GP25L PF01105.19 EIM82456.1 - 0.043 13.5 0.3 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GAS PF13851.1 EIM82456.1 - 0.05 12.7 6.6 0.026 13.6 1.9 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin PF00804.20 EIM82456.1 - 0.067 13.3 7.0 0.12 12.5 4.9 1.4 1 0 0 1 1 1 0 Syntaxin IncA PF04156.9 EIM82456.1 - 0.12 11.9 9.3 0.19 11.3 6.5 1.2 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EIM82456.1 - 0.17 11.1 7.8 0.033 13.4 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6 PF04111.7 EIM82456.1 - 2.3 7.1 8.0 3.6 6.5 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DDOST_48kD PF03345.9 EIM82457.1 - 1.4e-105 353.2 0.0 1.6e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta TACC PF05010.9 EIM82458.1 - 0.011 15.5 2.8 0.017 14.9 2.0 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF724 PF05266.9 EIM82458.1 - 0.16 11.5 7.2 0.25 10.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IFT20 PF14931.1 EIM82458.1 - 0.18 11.6 5.4 0.32 10.8 3.7 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FUSC PF04632.7 EIM82458.1 - 0.29 9.4 4.0 0.43 8.9 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 EIM82458.1 - 0.85 8.6 10.2 1.2 8.1 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EIM82458.1 - 1.7 9.0 6.3 1.4 9.3 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EIM82458.1 - 2.7 8.4 8.7 3.3 8.1 4.4 2.3 1 1 1 2 2 2 0 SlyX F-box-like PF12937.2 EIM82460.1 - 0.00065 19.3 1.3 0.0045 16.6 0.1 3.1 3 1 0 3 3 3 1 F-box-like ADK PF00406.17 EIM82461.1 - 1.5e-59 200.1 0.0 1.9e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIM82461.1 - 3.1e-14 52.3 0.0 5.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EIM82461.1 - 4e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM82461.1 - 0.00036 21.3 0.0 0.00057 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM82461.1 - 0.0031 16.6 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EIM82461.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 EIM82462.1 - 1.9e-06 27.5 0.7 1.7e-05 24.4 0.5 2.6 1 1 0 1 1 1 1 F-box-like Spore_YtrH PF14034.1 EIM82463.1 - 0.82 9.6 2.9 20 5.1 0.9 2.3 1 1 1 2 2 2 0 Sporulation protein YtrH Pro_CA PF00484.14 EIM82464.1 - 1.4e-35 122.5 0.1 7.1e-35 120.2 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 EIM82465.1 - 4.2e-38 130.7 0.1 2.6e-37 128.1 0.1 1.9 1 1 0 1 1 1 1 Carbonic anhydrase DEAD PF00270.24 EIM82467.1 - 6.8e-20 71.2 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM82467.1 - 5.5e-12 45.3 0.9 1.8e-10 40.5 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EIM82467.1 - 5.4e-11 42.9 0.1 1.6e-10 41.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EIM82467.1 - 4.9e-06 26.5 0.0 9.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.10 EIM82467.1 - 4.6e-05 23.3 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 EIM82468.1 - 4e-25 88.4 0.0 6e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82468.1 - 1.8e-15 56.7 0.0 3.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ice_nucleation PF00818.12 EIM82469.1 - 0.43 10.0 2.2 12 5.3 0.3 3.2 2 0 0 2 2 2 0 Ice nucleation protein repeat Myb_DNA-bind_2 PF08914.6 EIM82470.1 - 6.5e-06 25.8 4.6 0.031 14.0 0.2 2.6 2 0 0 2 2 2 2 Rap1 Myb domain ADH_N PF08240.7 EIM82471.1 - 1e-30 105.6 3.8 2.2e-30 104.6 2.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82471.1 - 4.9e-15 55.2 0.0 7.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82471.1 - 4e-05 24.4 0.0 7.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EIM82471.1 - 0.0016 17.5 0.3 0.0023 17.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_3 PF03447.11 EIM82471.1 - 0.0063 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIM82471.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SPT16 PF08644.6 EIM82472.1 - 2.8e-56 189.5 0.6 9e-56 187.9 0.4 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EIM82472.1 - 8.6e-39 132.6 0.3 5.6e-38 130.0 0.0 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EIM82472.1 - 2.3e-22 79.5 0.0 4.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EIM82472.1 - 2.7e-20 72.1 0.0 8.5e-20 70.5 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Metallophos PF00149.23 EIM82473.1 - 4.4e-10 39.2 0.4 1.2e-09 37.8 0.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM82473.1 - 2.5e-08 33.9 0.2 3.8e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4419 PF14388.1 EIM82475.1 - 3.5e-103 344.9 0.0 4.1e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) His_Phos_2 PF00328.17 EIM82476.1 - 7.6e-43 147.1 0.0 9.5e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HTH_9 PF08221.6 EIM82477.1 - 4.7e-20 71.2 1.8 4.1e-14 52.1 0.2 3.9 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EIM82477.1 - 5.5e-19 68.6 3.9 4.1e-16 59.2 2.2 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 EIM82477.1 - 2.6e-09 36.5 0.1 9.1e-08 31.5 0.1 3.3 4 0 0 4 4 4 1 TFIIE alpha subunit Draxin PF15550.1 EIM82477.1 - 0.79 9.3 3.9 1.4 8.4 2.7 1.4 1 0 0 1 1 1 0 Draxin Tubulin PF00091.20 EIM82478.1 - 1.9e-74 250.1 0.0 3.2e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIM82478.1 - 5.3e-47 158.9 0.1 1.1e-46 157.9 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIM82478.1 - 0.00018 21.5 0.0 0.00067 19.7 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIM82478.1 - 0.00058 19.3 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain 5_nucleotid_C PF02872.13 EIM82482.1 - 9.1e-26 90.6 0.0 1.7e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIM82482.1 - 1e-09 38.0 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EIM82482.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF2420 PF10336.4 EIM82483.1 - 6.1e-12 45.1 0.1 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF457 PF04307.9 EIM82484.1 - 0.048 12.9 0.7 0.072 12.4 0.5 1.5 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) BCS1_N PF08740.6 EIM82485.1 - 8.4e-24 84.2 1.6 1.5e-23 83.4 1.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIM82485.1 - 9.2e-18 64.7 0.0 5.5e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM82485.1 - 0.0028 16.7 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIM82485.1 - 0.0032 17.1 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIM82485.1 - 0.0042 17.0 0.0 0.0098 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EIM82485.1 - 0.0068 16.0 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM82485.1 - 0.012 16.3 0.0 0.031 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIM82485.1 - 0.019 14.6 0.0 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIM82485.1 - 0.019 14.3 0.0 0.048 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM82485.1 - 0.075 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIM82485.1 - 0.091 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HTH_Tnp_Tc5 PF03221.11 EIM82485.1 - 0.12 12.2 1.1 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF815 PF05673.8 EIM82485.1 - 0.14 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EIM82485.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 EIM82485.1 - 0.22 10.1 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus COX14 PF14880.1 EIM82486.1 - 5.4 6.7 6.1 0.83 9.3 0.4 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly MBF1 PF08523.5 EIM82487.1 - 2.2e-21 75.6 2.0 4.1e-21 74.7 1.4 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EIM82487.1 - 1.5e-13 50.3 0.1 2.3e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EIM82487.1 - 7.7e-07 29.0 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EIM82487.1 - 3.6e-05 23.8 0.0 5.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EIM82487.1 - 0.027 14.0 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_19 PF13245.1 EIM82488.1 - 0.0017 18.0 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIM82488.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIM82488.1 - 0.0049 16.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EIM82488.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RHSP PF07999.6 EIM82488.1 - 0.027 13.0 0.2 3.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon hot spot protein AAA_22 PF13401.1 EIM82488.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIM82488.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 EIM82488.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EIM82488.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NAD_binding_7 PF13241.1 EIM82489.1 - 7.8e-33 112.8 0.0 1.9e-32 111.5 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIM82489.1 - 1.7e-19 68.9 0.1 2.8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIM82489.1 - 1.4e-14 52.7 0.8 2.2e-14 52.0 0.5 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ELFV_dehydrog PF00208.16 EIM82489.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox_3 PF13738.1 EIM82489.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SR-25 PF10500.4 EIM82489.1 - 3.6 6.9 6.7 5.7 6.3 4.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tetraspannin PF00335.15 EIM82490.1 - 6.5e-06 25.5 16.8 1e-05 24.9 11.6 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.1 EIM82490.1 - 0.0079 15.3 1.1 0.66 9.0 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4191) Arteri_Gl PF00951.13 EIM82490.1 - 0.017 14.7 0.0 0.017 14.7 0.0 2.5 2 1 1 3 3 3 0 Arterivirus GL envelope glycoprotein IFNGR1 PF07140.6 EIM82490.1 - 0.021 14.5 0.5 0.91 9.2 0.7 2.2 1 1 1 2 2 2 0 Interferon gamma receptor (IFNGR1) DUF1440 PF07274.7 EIM82490.1 - 0.15 12.0 2.9 0.3 11.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) Baculo_11_kDa PF06143.6 EIM82490.1 - 0.18 11.1 4.9 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3321 PF11968.3 EIM82491.1 - 3.3e-59 200.1 0.0 5.6e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EIM82491.1 - 6.5e-05 22.7 0.0 0.00034 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Neur_chan_memb PF02932.11 EIM82491.1 - 0.0095 15.8 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Methyltransf_11 PF08241.7 EIM82491.1 - 0.016 15.6 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIM82491.1 - 0.14 12.7 0.0 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Mucin PF01456.12 EIM82491.1 - 3.5 7.3 14.4 5.8 6.6 10.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein F-box-like PF12937.2 EIM82492.1 - 1.7e-05 24.4 0.1 0.001 18.7 0.0 2.8 2 0 0 2 2 2 2 F-box-like RNA12 PF10443.4 EIM82494.1 - 1.2e-113 379.8 0.0 3.5e-113 378.3 0.0 1.8 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 EIM82494.1 - 0.00018 21.5 0.2 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RRM_1 PF00076.17 EIM82494.1 - 0.0014 18.2 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EIM82494.1 - 0.003 17.3 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EIM82494.1 - 0.059 13.2 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM82494.1 - 0.068 13.3 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 EIM82494.1 - 0.13 12.2 0.0 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3484 PF11983.3 EIM82494.1 - 0.16 12.8 1.8 0.51 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) F-box-like PF12937.2 EIM82495.1 - 3.7e-05 23.3 0.3 0.00023 20.7 0.2 2.2 1 1 0 1 1 1 1 F-box-like DUF974 PF06159.8 EIM82496.1 - 5.6e-60 202.8 0.0 8.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Epimerase PF01370.16 EIM82500.1 - 2.8e-19 69.4 0.0 4.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM82500.1 - 2e-12 47.4 0.1 9.1e-12 45.3 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM82500.1 - 4.2e-11 42.0 0.0 6.5e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIM82500.1 - 5.7e-08 32.3 0.2 9.7e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIM82500.1 - 7.7e-08 31.5 0.0 1.7e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIM82500.1 - 6.7e-05 22.8 1.2 0.0002 21.3 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM82500.1 - 0.13 11.8 0.3 0.63 9.6 0.2 2.1 1 1 0 1 1 1 0 KR domain DUF4536 PF15055.1 EIM82501.1 - 0.0028 17.6 1.7 0.0031 17.5 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) CHAT PF12770.2 EIM82502.1 - 1.4e-38 132.6 0.1 2.4e-38 131.9 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM82502.1 - 5.6e-25 87.0 32.7 0.0013 18.5 0.0 12.8 6 4 9 15 15 15 7 Tetratricopeptide repeat TPR_11 PF13414.1 EIM82502.1 - 2e-23 81.8 18.1 0.0047 16.5 0.0 9.7 6 3 4 10 10 10 7 TPR repeat TPR_8 PF13181.1 EIM82502.1 - 2.5e-08 33.0 0.4 0.41 10.5 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82502.1 - 2e-05 24.1 7.5 17 5.6 0.0 9.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82502.1 - 2.6e-05 24.4 17.5 5.8 7.8 0.0 9.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TOM20_plant PF06552.7 EIM82502.1 - 0.0014 18.2 0.1 8.3 5.9 0.0 4.1 4 1 1 5 5 5 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.1 EIM82502.1 - 0.0031 17.2 16.4 18 5.4 0.0 9.8 12 1 0 12 12 12 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82502.1 - 0.11 12.1 11.4 24 4.7 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat V-ATPase_H_N PF03224.9 EIM82503.1 - 2.2e-84 283.2 0.1 1.9e-83 280.1 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EIM82503.1 - 1.3e-42 144.5 1.2 2.9e-42 143.3 0.1 2.2 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 EIM82503.1 - 3.6e-07 30.3 0.3 0.00072 19.7 0.0 2.9 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EIM82503.1 - 1.7e-06 27.5 0.3 0.29 11.3 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 EIM82503.1 - 2.9e-05 22.6 0.3 0.018 13.3 0.0 2.6 3 0 0 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EIM82503.1 - 5.7e-05 22.3 0.0 0.00014 21.0 0.0 1.6 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.18 EIM82503.1 - 0.003 17.3 1.0 4.6 7.2 0.2 4.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF1344 PF07076.6 EIM82503.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF2435 PF10363.4 EIM82503.1 - 0.085 12.7 2.8 8.2 6.4 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EIM82503.1 - 0.34 11.4 7.1 19 5.9 0.0 4.7 4 1 2 6 6 6 0 HEAT-like repeat An_peroxidase PF03098.10 EIM82504.1 - 9.6e-72 242.0 0.0 2.7e-69 233.9 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EIM82504.1 - 5.8e-06 25.1 0.0 6.1e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.4 EIM82505.1 - 2.3e-78 263.3 0.3 2.9e-78 263.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIM82505.1 - 0.0055 16.4 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EIM82506.1 - 2.4e-30 105.4 0.0 9.9e-29 100.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIM82508.1 - 3.1e-68 230.3 0.1 1.7e-67 227.9 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF4197 PF13852.1 EIM82509.1 - 0.21 11.0 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) DDE_1 PF03184.14 EIM82511.1 - 4.8e-08 32.4 0.0 5.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM82511.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Endonuclease_NS PF01223.18 EIM82513.1 - 1.6e-52 178.1 0.0 1.8e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF1118 PF06549.7 EIM82514.1 - 0.85 9.7 3.6 2 8.5 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) MRP-L46 PF11788.3 EIM82515.1 - 1.3e-15 57.9 0.4 2.8e-15 56.9 0.2 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EIM82515.1 - 3.2e-06 26.8 0.1 5.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain R3H PF01424.17 EIM82516.1 - 2.9e-12 46.1 0.1 7.8e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EIM82516.1 - 2.4e-07 30.2 0.0 6.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM82516.1 - 8.3e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM82516.1 - 0.00015 21.5 0.2 0.00033 20.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 EIM82516.1 - 9.5 5.9 18.1 0.048 13.3 5.4 2.6 2 0 0 2 2 2 0 SUZ-C motif DNA_methylase PF00145.12 EIM82518.1 - 4.4e-30 104.9 0.0 9.7e-28 97.2 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase fn3 PF00041.16 EIM82518.1 - 0.0019 18.2 0.8 5 7.3 0.0 3.6 3 0 0 3 3 3 2 Fibronectin type III domain HOOK PF05622.7 EIM82519.1 - 2.3e-54 184.4 73.5 1e-52 178.9 24.5 3.8 2 2 1 3 3 3 3 HOOK protein NYD-SP28_assoc PF14775.1 EIM82519.1 - 0.00052 19.6 1.0 0.00052 19.6 0.7 5.1 5 0 0 5 5 5 1 Sperm tail C-terminal domain TPR_MLP1_2 PF07926.7 EIM82519.1 - 0.00075 19.2 9.1 0.00075 19.2 6.3 7.0 5 1 2 7 7 7 2 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EIM82519.1 - 0.012 15.5 3.0 0.012 15.5 2.1 8.2 9 2 1 10 10 10 0 bZIP transcription factor Reo_sigmaC PF04582.7 EIM82519.1 - 6.4 5.8 17.8 0.61 9.2 0.4 3.8 3 1 1 4 4 4 0 Reovirus sigma C capsid protein DNA_methylase PF00145.12 EIM82520.1 - 4.9e-15 55.4 0.0 1.2e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase PITH PF06201.8 EIM82521.1 - 7.8e-40 136.1 0.2 1e-39 135.7 0.2 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EIM82521.1 - 2.4e-20 72.1 0.0 6.9e-16 57.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 EIM82521.1 - 0.019 15.0 0.1 2.2 8.4 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin-like C-C_Bond_Lyase PF15617.1 EIM82521.1 - 0.019 13.7 0.1 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Sugar_tr PF00083.19 EIM82522.1 - 1.6e-83 280.8 10.8 5.1e-83 279.1 7.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM82522.1 - 8.7e-23 80.5 20.7 1.4e-22 79.8 14.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIM82522.1 - 6.4e-06 24.8 26.4 0.00028 19.4 1.5 4.0 2 2 1 4 4 4 3 MFS/sugar transport protein TRI12 PF06609.8 EIM82522.1 - 1.1e-05 23.8 9.8 4.5e-05 21.8 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.2 EIM82523.1 - 2.1e-09 36.9 0.9 7e-09 35.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 EIM82524.1 - 7.6e-25 87.3 69.3 2.4e-21 75.8 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMA7 PF09072.5 EIM82526.1 - 2.4e-19 69.5 22.8 2.6e-19 69.4 15.8 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Prp19_bind PF06991.6 EIM82526.1 - 0.039 13.2 3.6 0.046 12.9 2.5 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF2098 PF09871.4 EIM82526.1 - 0.33 10.9 2.0 0.36 10.7 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Abhydrolase_5 PF12695.2 EIM82527.1 - 5.1e-11 42.5 0.2 1.2e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM82527.1 - 2.9e-08 33.2 0.0 5.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIM82527.1 - 2.2e-07 30.9 6.1 3.3e-07 30.4 3.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIM82527.1 - 0.013 14.9 0.0 0.67 9.3 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Not1 PF04054.10 EIM82528.1 - 1.3e-117 392.8 0.3 4.5e-117 391.1 0.1 2.0 2 1 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIM82528.1 - 3.7e-53 179.1 0.0 1.1e-52 177.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FdhE PF04216.7 EIM82528.1 - 0.046 13.4 0.7 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation SR-25 PF10500.4 EIM82529.1 - 4.5 6.6 7.5 10 5.5 0.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Thg1C PF14413.1 EIM82530.1 - 1.6e-46 156.9 0.2 2.3e-46 156.3 0.2 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EIM82530.1 - 1.4e-44 151.0 0.0 2.1e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase SbmA_BacA PF05992.7 EIM82530.1 - 0.018 14.2 1.3 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 SbmA/BacA-like family DUF4551 PF15087.1 EIM82530.1 - 0.15 10.3 1.7 0.19 10.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TSGP1 PF07771.6 EIM82530.1 - 2.3 8.1 7.6 11 5.9 4.3 2.3 2 1 0 2 2 2 0 Tick salivary peptide group 1 Steroid_dh PF02544.11 EIM82531.1 - 2.6e-39 134.3 0.6 4.1e-39 133.7 0.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EIM82531.1 - 8.1e-05 21.9 0.0 0.00018 20.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIM82531.1 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 EIM82531.1 - 0.058 13.9 0.3 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UAE_UbL PF14732.1 EIM82531.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiS PF02597.15 EIM82531.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ThiS family Acyl-CoA_dh_M PF02770.14 EIM82533.1 - 5e-06 25.9 0.0 1.3e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydro_lipase PF04083.11 EIM82533.1 - 0.066 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3278 PF11683.3 EIM82534.1 - 0.34 10.9 5.5 0.54 10.2 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DDE_1 PF03184.14 EIM82536.1 - 1.1e-05 24.7 0.1 1.3e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM82536.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Alpha-amylase PF00128.19 EIM82537.1 - 4.4e-60 203.7 0.9 7.1e-60 203.0 0.6 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIM82537.1 - 9.2e-16 57.7 0.2 1.9e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) APH PF01636.18 EIM82539.1 - 0.00086 19.1 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM82539.1 - 0.0031 16.7 0.0 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Fasciclin PF02469.17 EIM82540.1 - 3.2e-29 101.5 0.0 5.8e-13 48.9 0.0 4.0 3 1 0 3 3 3 3 Fasciclin domain IPPT PF01715.12 EIM82541.1 - 6.8e-47 159.6 2.9 4.8e-20 71.6 0.0 4.1 4 0 0 4 4 4 3 IPP transferase AAA_18 PF13238.1 EIM82541.1 - 0.017 15.4 0.0 0.017 15.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EIM82541.1 - 0.025 15.4 0.0 0.025 15.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIM82541.1 - 0.057 13.5 0.7 0.4 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF2201_N PF13203.1 EIM82541.1 - 0.11 11.6 8.8 0.31 10.1 6.1 1.9 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EIM82541.1 - 9.1 4.1 16.9 1.9e+02 -0.2 0.0 1.9 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_L18e PF00828.14 EIM82542.1 - 7.1e-23 81.3 0.1 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PdxA PF04166.7 EIM82544.1 - 0.0049 16.1 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA zf-C2H2_6 PF13912.1 EIM82544.1 - 0.014 15.2 0.9 0.03 14.2 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3816 PF12822.2 EIM82546.1 - 1.2 9.0 8.8 4.6 7.0 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) O-antigen_lig PF13425.1 EIM82546.1 - 2.5 8.1 8.5 2 8.4 4.2 2.0 1 1 1 2 2 2 0 O-antigen ligase like membrane protein p450 PF00067.17 EIM82547.1 - 1.1e-67 228.5 0.0 1.3e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82550.1 - 2.6e-53 181.1 0.0 5.8e-49 166.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIM82551.1 - 1.2e-07 30.5 0.0 1.3e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIM82552.1 - 2.1e-21 76.0 35.6 2.1e-21 76.0 24.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EIM82553.1 - 2.8e-12 47.0 0.0 3.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3696 PF12476.3 EIM82553.1 - 0.48 10.4 5.0 2.3 8.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3696) CbiM PF01891.11 EIM82554.1 - 0.038 13.6 9.3 0.082 12.4 2.0 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region p450 PF00067.17 EIM82555.1 - 1.5e-21 76.4 0.0 1.6e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82556.1 - 2.5e-05 23.0 0.0 3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 EIM82557.1 - 3.7e-22 78.9 26.6 5.7e-22 78.4 18.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase ICMT PF04140.9 EIM82558.1 - 5.2e-15 55.4 0.1 1.2e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM82558.1 - 2.1e-13 50.2 0.2 1.1e-11 44.7 0.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM82558.1 - 8.1e-06 24.6 0.1 1.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FA_desaturase PF00487.19 EIM82559.1 - 1.3e-31 109.9 24.1 2.5e-31 109.0 16.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3796 PF12676.2 EIM82559.1 - 0.46 10.7 6.4 0.38 10.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) FA_desaturase PF00487.19 EIM82560.1 - 3.8e-30 105.1 21.3 3.8e-30 105.1 14.8 1.8 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EIM82560.1 - 0.00031 20.7 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Glyco_transf_41 PF13844.1 EIM82560.1 - 0.14 10.0 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Amino_oxidase PF01593.19 EIM82561.1 - 1.4e-36 126.5 0.0 3.5e-36 125.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIM82561.1 - 8.8e-10 38.4 0.1 2e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM82561.1 - 0.0081 15.9 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EIM82561.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIM82561.1 - 0.099 11.2 0.2 1.4 7.4 0.0 2.5 2 1 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIM82561.1 - 0.11 12.5 0.0 0.46 10.5 0.0 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM82561.1 - 0.13 11.2 0.4 0.28 10.1 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain WD40 PF00400.27 EIM82562.1 - 6.1e-49 162.2 3.9 6.1e-11 41.7 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 EIM82562.1 - 2.2e-38 131.5 3.3 3.2e-36 124.6 2.2 4.5 5 0 0 5 5 5 2 Striatin family Nup160 PF11715.3 EIM82562.1 - 0.059 11.5 0.0 7 4.6 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIM82562.1 - 0.14 10.9 0.0 0.14 10.9 0.0 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Utp8 PF10395.4 EIM82562.1 - 1.6 6.8 0.0 1.6 6.8 0.0 2.2 2 1 0 2 2 2 0 Utp8 family PDEase_II PF02112.10 EIM82563.1 - 1.2e-44 152.6 0.0 4.8e-41 140.7 0.0 2.4 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EIM82563.1 - 1.4e-08 34.5 0.3 2.2e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM82563.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily AflR PF08493.5 EIM82564.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein EF-hand_4 PF12763.2 EIM82565.1 - 8.4e-38 128.2 0.0 1.3e-15 56.9 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIM82565.1 - 1.5e-06 28.2 0.0 0.001 19.1 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.26 EIM82565.1 - 1.6e-06 27.7 0.0 3.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EIM82565.1 - 6.5e-06 25.0 0.0 0.12 11.7 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIM82565.1 - 0.017 14.7 0.0 0.25 10.9 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EIM82565.1 - 0.028 14.2 1.2 10 6.3 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain CENP-F_leu_zip PF10473.4 EIM82565.1 - 0.065 13.0 29.0 0.0089 15.8 6.0 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.10 EIM82565.1 - 0.59 10.1 23.4 2.5 8.0 7.2 2.2 1 1 1 2 2 2 0 Fez1 WEMBL PF05701.6 EIM82565.1 - 0.84 8.0 34.5 8.3 4.7 23.9 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF812 PF05667.6 EIM82565.1 - 0.93 7.9 18.9 1.5 7.2 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.6 EIM82565.1 - 1.7 8.4 23.6 10 5.8 16.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EIM82565.1 - 2 8.1 26.9 0.36 10.5 7.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIM82565.1 - 4.1 6.5 10.5 1.3 8.0 3.2 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ADIP PF11559.3 EIM82565.1 - 6.2 6.7 24.6 1 9.2 4.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EIM82565.1 - 9.7 5.0 24.5 11 4.7 4.5 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 UQ_con PF00179.21 EIM82566.1 - 4e-44 149.4 0.1 4.9e-44 149.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIM82566.1 - 8.9e-05 22.3 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EIM82566.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.11 EIM82568.1 - 8e-07 28.0 62.8 1.1e-05 24.3 39.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM82568.1 - 0.0011 17.2 32.1 0.0066 14.6 22.2 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.8 EIM82568.1 - 0.12 12.2 0.3 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA MFS_1 PF07690.11 EIM82569.1 - 1.2e-08 34.1 57.6 4.5e-05 22.3 28.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM82569.1 - 1.2e-05 23.7 30.3 0.00011 20.5 21.0 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EIM82569.1 - 0.11 12.4 3.5 0.29 11.1 0.7 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.17 EIM82571.1 - 2.2e-10 39.7 0.0 2.5e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82572.1 - 2.9e-43 148.0 0.0 3.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82573.1 - 7.6e-50 169.7 0.0 1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EIM82574.1 - 2e-23 83.4 0.0 2.4e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM82574.1 - 1.5e-17 63.9 0.0 2.4e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM82574.1 - 5.2e-10 39.2 0.0 3.1e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM82574.1 - 0.05 13.8 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EIM82574.1 - 0.05 13.2 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 EIM82574.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF915 PF06028.6 EIM82574.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Epimerase PF01370.16 EIM82575.1 - 5.9e-20 71.7 0.0 8.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM82575.1 - 6.3e-07 28.3 0.0 2.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM82575.1 - 1.1e-05 25.4 0.1 3.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM82575.1 - 0.0001 21.3 0.0 0.002 17.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EIM82575.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RTC PF01137.16 EIM82576.1 - 6.1e-66 221.4 0.0 3.2e-33 114.4 0.0 2.0 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIM82576.1 - 4.8e-22 77.9 0.0 8.5e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.10 EIM82577.1 - 6.5e-92 307.6 0.1 6.5e-92 307.6 0.1 1.5 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family APH PF01636.18 EIM82580.1 - 1.3e-07 31.5 0.0 7e-05 22.6 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIM82580.1 - 1.8e-06 27.3 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain gerPA PF10676.4 EIM82581.1 - 2 8.3 5.4 0.2 11.5 0.5 1.7 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF PHD PF00628.24 EIM82582.1 - 8e-17 60.6 15.6 2.7e-11 42.9 2.8 2.6 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 EIM82582.1 - 0.00041 20.4 1.9 0.0021 18.1 0.4 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EIM82582.1 - 0.0015 17.8 2.5 0.021 14.1 0.4 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EIM82582.1 - 0.069 12.8 8.0 2.4 7.9 0.5 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EIM82582.1 - 0.32 11.0 11.2 1.4 8.9 0.3 3.0 2 1 1 3 3 3 0 RING-like domain PHD_2 PF13831.1 EIM82582.1 - 0.43 9.9 20.9 0.71 9.2 3.1 3.6 3 2 0 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EIM82582.1 - 0.55 10.2 3.4 0.54 10.2 0.6 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 EIM82582.1 - 5.1 6.9 14.7 1.6 8.5 0.7 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Acyltransferase PF01553.16 EIM82583.1 - 1.1e-15 57.2 0.0 1.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase F-box-like PF12937.2 EIM82584.1 - 1e-09 37.9 0.8 2.8e-09 36.5 0.5 1.8 1 0 0 1 1 1 1 F-box-like DUF2076 PF09849.4 EIM82585.1 - 0.006 16.6 3.2 0.006 16.6 2.2 3.3 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2076) DUF4591 PF15261.1 EIM82585.1 - 0.23 11.7 1.4 1.5 9.0 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4591) ATP-synt_ab PF00006.20 EIM82586.1 - 3.6e-113 376.3 0.0 5.9e-113 375.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIM82586.1 - 3.6e-23 82.1 2.5 7.3e-23 81.2 1.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIM82586.1 - 2.4e-14 53.2 2.9 7e-14 51.7 2.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EIM82587.1 - 1.5e-40 138.4 0.0 3.3e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 EIM82587.1 - 1.8e-32 112.1 0.0 2.9e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIM82587.1 - 6.3e-15 54.8 0.0 4.3e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EIM82587.1 - 5.4e-05 23.3 0.0 0.0024 18.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIM82587.1 - 7.4e-05 22.4 0.0 0.00026 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM82587.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIM82587.1 - 0.0021 18.0 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EIM82587.1 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIM82587.1 - 0.006 17.3 0.1 0.019 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIM82587.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM82587.1 - 0.018 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM82587.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EIM82587.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIM82587.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.4 3 0 0 3 3 2 0 Part of AAA domain Sigma54_activ_2 PF14532.1 EIM82587.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIM82587.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EIM82587.1 - 0.083 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EIM82587.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EIM82587.1 - 0.096 11.3 0.1 0.22 10.1 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus Mg_chelatase PF01078.16 EIM82587.1 - 0.1 11.7 0.5 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIM82587.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIM82587.1 - 0.19 11.9 0.0 0.54 10.4 0.0 1.7 2 0 0 2 2 1 0 RNA helicase PAGK PF15284.1 EIM82588.1 - 2.6 7.8 5.4 3.4 7.4 0.9 2.5 2 0 0 2 2 2 0 Phage-encoded virulence factor ING PF12998.2 EIM82589.1 - 5.1e-12 45.9 0.0 3.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIM82589.1 - 1.5e-09 37.3 8.7 2.4e-09 36.7 6.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIM82589.1 - 0.29 10.4 4.5 0.52 9.6 3.1 1.4 1 0 0 1 1 1 0 PHD-finger ADH_zinc_N_2 PF13602.1 EIM82590.1 - 3.3e-21 76.4 0.0 6.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM82590.1 - 4.7e-08 32.6 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-MYND PF01753.13 EIM82591.1 - 9.5e-08 31.7 11.5 9.5e-08 31.7 7.9 1.8 2 0 0 2 2 2 1 MYND finger Ank_2 PF12796.2 EIM82591.1 - 0.00037 20.7 0.0 0.0013 19.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) SEC-C PF02810.10 EIM82591.1 - 0.0015 18.0 5.7 0.0015 18.0 4.0 2.4 2 0 0 2 2 2 1 SEC-C motif Ank PF00023.25 EIM82591.1 - 0.012 15.3 0.0 54 3.8 0.0 4.3 3 1 1 4 4 4 0 Ankyrin repeat NDUF_B4 PF07225.7 EIM82591.1 - 0.061 13.1 0.1 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Gar1 PF04410.9 EIM82592.1 - 4.8e-42 143.0 0.0 4.8e-42 143.0 0.0 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region AAA PF00004.24 EIM82593.1 - 4.3e-61 204.9 0.0 2.7e-44 150.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM82593.1 - 4.4e-09 37.2 0.0 0.0053 17.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM82593.1 - 4.9e-09 36.4 0.4 0.0038 17.2 0.0 3.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EIM82593.1 - 1.4e-07 31.2 0.1 0.017 14.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIM82593.1 - 7.1e-07 28.8 0.2 0.0026 17.4 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 EIM82593.1 - 8.1e-07 28.9 0.0 0.054 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM82593.1 - 3.1e-06 27.3 0.1 0.0038 17.3 0.0 3.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIM82593.1 - 1.2e-05 24.5 0.0 0.0039 16.2 0.0 2.7 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EIM82593.1 - 1.2e-05 24.1 0.0 0.02 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EIM82593.1 - 0.00013 21.8 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIM82593.1 - 0.00017 21.0 0.0 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIM82593.1 - 0.00046 20.5 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EIM82593.1 - 0.0005 20.0 0.0 0.018 14.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EIM82593.1 - 0.00068 19.7 0.0 0.087 12.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EIM82593.1 - 0.00073 19.5 0.1 0.13 12.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 EIM82593.1 - 0.00074 19.0 0.0 0.98 8.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIM82593.1 - 0.0012 17.9 0.0 0.21 10.6 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin Vps4_C PF09336.5 EIM82593.1 - 0.0015 18.3 0.0 0.14 12.0 0.0 3.7 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 EIM82593.1 - 0.0016 17.6 0.2 0.035 13.2 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 EIM82593.1 - 0.0017 17.2 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIM82593.1 - 0.0022 17.6 0.0 0.091 12.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIM82593.1 - 0.0027 17.1 4.1 0.0052 16.2 0.1 3.0 3 1 0 3 3 2 1 AAA domain PhoH PF02562.11 EIM82593.1 - 0.0065 15.7 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EIM82593.1 - 0.0068 16.0 0.0 0.41 10.2 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIM82593.1 - 0.02 14.5 1.7 2.3 7.8 0.0 3.8 4 0 0 4 4 4 0 NACHT domain AAA_30 PF13604.1 EIM82593.1 - 0.02 14.4 0.1 2 7.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EIM82593.1 - 0.021 13.7 0.0 1 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 EIM82593.1 - 0.024 14.2 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EIM82593.1 - 0.027 14.0 1.6 0.079 12.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIM82593.1 - 0.03 13.4 0.1 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 KaiC SKI PF01202.17 EIM82593.1 - 0.031 14.1 0.4 6 6.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase T2SE PF00437.15 EIM82593.1 - 0.047 12.5 0.0 0.76 8.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EIM82593.1 - 0.058 12.2 0.0 1 8.1 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain Ribosomal_S21 PF01165.15 EIM82593.1 - 0.079 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S21 Sigma54_activ_2 PF14532.1 EIM82593.1 - 0.085 12.8 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EIM82593.1 - 0.13 11.9 0.1 3.6 7.2 0.0 2.6 3 0 0 3 3 2 0 NTPase AAA_6 PF12774.2 EIM82593.1 - 0.22 11.0 0.0 0.53 9.7 0.0 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 PhoD PF09423.5 EIM82594.1 - 1.5e-45 155.6 0.2 3.2e-39 134.7 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase DUF1690 PF07956.6 EIM82595.1 - 1.4e-10 41.3 2.5 1.7e-09 37.7 1.7 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF4588 PF15251.1 EIM82595.1 - 0.079 12.9 1.1 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Atrophin-1 PF03154.10 EIM82595.1 - 0.95 7.5 6.3 1.2 7.1 4.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Fungal_trans PF04082.13 EIM82597.1 - 7.9e-24 83.9 0.4 1.9e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM82597.1 - 3.5e-06 26.8 11.6 3.5e-06 26.8 8.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence_reg PF04520.8 EIM82597.1 - 0.3 11.5 3.0 0.55 10.7 2.1 1.4 1 0 0 1 1 1 0 Senescence regulator WD40 PF00400.27 EIM82598.1 - 0.00099 18.9 0.2 0.00099 18.9 0.1 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ADK PF00406.17 EIM82599.1 - 2.6e-45 153.9 0.4 8e-45 152.4 0.3 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EIM82599.1 - 4.1e-11 43.2 0.1 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM82599.1 - 5.9e-08 33.5 0.0 8.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EIM82599.1 - 5.7e-06 25.8 1.2 0.048 13.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EIM82599.1 - 0.00014 21.7 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM82599.1 - 0.014 14.5 0.2 0.07 12.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EIM82599.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAS_7 PF12860.2 EIM82599.1 - 0.034 14.1 0.2 0.8 9.7 0.1 2.2 2 0 0 2 2 2 0 PAS fold CN_hydrolase PF00795.17 EIM82600.1 - 4.1e-28 97.9 0.0 7.2e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ PF00226.26 EIM82601.1 - 2.9e-23 81.3 1.1 5.3e-23 80.5 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIM82601.1 - 3.5e-18 65.2 1.1 1.5e-16 60.0 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIM82601.1 - 8e-15 54.6 15.7 1.4e-14 53.8 10.9 1.4 1 0 0 1 1 1 1 DnaJ central domain FAD_binding_4 PF01565.18 EIM82601.1 - 0.11 11.9 0.7 0.42 10.0 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain HypA PF01155.14 EIM82601.1 - 0.17 11.5 10.7 82 2.9 7.4 2.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_3 PF00933.16 EIM82602.1 - 8.2e-78 261.4 0.0 1.1e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM82602.1 - 1.3e-71 240.7 0.0 4.3e-71 239.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM82602.1 - 6e-23 80.5 0.0 1.4e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIM82602.1 - 6.4e-11 42.0 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Rcd1 PF04078.8 EIM82602.1 - 0.34 9.7 0.0 14 4.4 0.0 2.1 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like PIG-S PF10510.4 EIM82602.1 - 0.4 9.2 0.0 0.6 8.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein MFS_1 PF07690.11 EIM82610.1 - 1.4e-13 50.3 44.9 1.4e-13 50.3 31.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM82610.1 - 1.4e-05 23.8 11.5 1.4e-05 23.8 8.0 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2236 PF09995.4 EIM82611.1 - 4.9e-12 45.6 0.0 8.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) ADH_N PF08240.7 EIM82612.1 - 1.3e-25 89.2 8.8 2.2e-25 88.5 6.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM82612.1 - 1.1e-15 57.3 0.1 6.3e-15 54.8 0.0 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM82612.1 - 0.004 16.3 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM82612.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain S1-P1_nuclease PF02265.11 EIM82613.1 - 1.6e-72 244.2 0.0 1.8e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nop25 PF09805.4 EIM82614.1 - 9.7e-16 58.0 22.2 9.7e-16 58.0 15.4 2.8 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) R3H PF01424.17 EIM82616.1 - 7.4e-14 51.1 0.0 2.5e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EIM82616.1 - 4.9e-06 26.2 0.2 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIM82616.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site HTH_21 PF13276.1 EIM82616.1 - 0.052 13.5 0.1 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 HTH-like domain DUF3628 PF12300.3 EIM82616.1 - 3.7 7.5 17.6 0.14 12.1 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Amidase PF01425.16 EIM82617.1 - 1.4e-64 218.5 0.2 7.3e-62 209.6 0.0 2.3 2 0 0 2 2 2 2 Amidase PEPCK_ATP PF01293.15 EIM82618.1 - 2.7e-218 725.1 0.0 3.2e-218 724.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EIM82618.1 - 0.016 14.7 0.0 0.048 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EIM82618.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM82618.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EIM82618.1 - 0.11 11.8 0.2 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 EIM82619.1 - 1.1e-05 25.3 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EIM82619.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EIM82619.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM82619.1 - 0.051 13.6 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 EIM82620.1 - 8.3e-23 79.9 0.4 3.3e-22 78.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain RGCC PF15151.1 EIM82620.1 - 0.0068 16.8 0.4 0.017 15.5 0.3 1.7 1 0 0 1 1 1 1 Response gene to complement 32 protein family UvrD_C_2 PF13538.1 EIM82620.1 - 0.088 12.9 1.0 0.22 11.6 0.0 2.2 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Yae1_N PF09811.4 EIM82621.1 - 4.4e-05 22.9 6.6 8.3e-05 22.0 3.0 2.3 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF1423 PF07227.6 EIM82621.1 - 0.18 10.4 9.9 0.24 10.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Fmp27_WPPW PF10359.4 EIM82621.1 - 0.22 9.9 8.3 0.34 9.2 5.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMF_TATA_bd PF12325.3 EIM82621.1 - 0.71 9.6 12.7 0.72 9.6 7.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 EIM82621.1 - 0.85 7.9 5.8 1.2 7.5 4.0 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EIM82621.1 - 1.2 8.7 10.8 1.8 8.0 7.5 1.3 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 EIM82621.1 - 2.5 7.9 16.5 0.81 9.5 8.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.6 EIM82621.1 - 2.9 6.4 5.5 4 6.0 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EIM82621.1 - 4.8 6.1 13.2 7.2 5.5 9.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 p450 PF00067.17 EIM82622.1 - 5e-54 183.5 0.0 9e-54 182.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM82623.1 - 5.1e-55 186.8 0.0 7.4e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.18 EIM82624.1 - 2.4e-171 555.4 28.5 7.6e-34 114.9 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 EIM82624.1 - 1.4e-96 316.2 28.1 8.4e-19 67.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM82624.1 - 8.7e-30 102.8 13.7 0.00025 21.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIM82624.1 - 4.5e-26 91.4 1.6 0.0025 17.5 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIM82624.1 - 5.2e-17 61.7 5.3 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIM82624.1 - 1.2e-16 60.6 3.4 0.22 11.7 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIM82624.1 - 3e-13 49.6 0.0 2 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EIM82624.1 - 8.3e-09 34.8 1.9 1.5 7.9 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase FlgD_ig PF13860.1 EIM82624.1 - 1.1e-08 34.6 8.0 4.6 7.0 0.0 5.3 5 0 0 5 5 5 5 FlgD Ig-like domain TUG-UBL1 PF11470.3 EIM82624.1 - 4.3e-07 29.7 7.9 9 6.3 0.0 5.2 5 0 0 5 5 5 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EIM82624.1 - 6.4e-05 23.2 1.2 99 3.3 0.0 5.1 5 0 0 5 5 5 0 ACT domain Big_3_3 PF13750.1 EIM82624.1 - 0.00019 20.9 0.0 69 2.8 0.0 4.8 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EIM82624.1 - 0.0037 15.6 18.4 5.4 5.1 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 EIM82624.1 - 0.017 15.0 19.3 12 5.9 0.2 5.6 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 EIM82624.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 EIM82624.1 - 0.075 13.0 10.8 75 3.4 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 EIM82624.1 - 5 7.1 10.4 2.2e+02 1.8 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EIM82624.1 - 7.6 6.6 17.8 1.2e+02 2.8 0.1 6.9 5 5 0 5 5 5 0 FERM N-terminal domain CDC48_2 PF02933.12 EIM82624.1 - 9.1 6.0 19.2 58 3.4 0.1 5.1 5 0 0 5 5 5 0 Cell division protein 48 (CDC48), domain 2 FAM72 PF14976.1 EIM82625.1 - 2.2e-05 24.3 3.9 7.1e-05 22.6 2.7 1.7 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 EIM82625.1 - 0.02 14.9 0.3 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Flavin_Reduct PF01613.13 EIM82626.1 - 1.9e-22 79.7 0.8 1.9e-22 79.7 0.5 1.4 2 0 0 2 2 2 1 Flavin reductase like domain DUF447 PF04289.7 EIM82626.1 - 0.0045 16.5 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Mg_trans_NIPA PF05653.9 EIM82627.1 - 1.8e-16 59.9 12.6 1.5e-08 34.0 3.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIM82627.1 - 8.9e-06 25.8 4.9 8.9e-06 25.8 3.4 4.2 2 2 0 2 2 2 1 Multidrug resistance efflux transporter Neur_chan_memb PF02932.11 EIM82627.1 - 0.0002 21.3 0.0 0.00053 19.9 0.0 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EamA PF00892.15 EIM82627.1 - 0.0054 16.7 8.4 0.0054 16.7 5.8 3.4 3 1 0 3 3 3 2 EamA-like transporter family NOA36 PF06524.7 EIM82627.1 - 1.9 7.6 7.2 2.9 7.0 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein CAF-1_p150 PF11600.3 EIM82628.1 - 1.9 7.8 31.9 3.9 6.8 21.9 1.7 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RdRP PF05183.7 EIM82629.1 - 4.3e-110 369.0 0.0 8.1e-110 368.2 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.1 EIM82629.1 - 5.5e-41 140.1 0.0 1.9e-40 138.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM82629.1 - 2.7e-08 33.6 6.3 0.0012 18.4 0.1 4.3 1 1 2 3 3 3 3 AAA domain UvrD_C_2 PF13538.1 EIM82629.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Poxvirus PF06227.7 EIM82629.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus AAA_28 PF13521.1 EIM82630.1 - 5.7e-22 78.4 0.0 6.4e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM82630.1 - 2.8e-07 31.3 0.0 4e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM82630.1 - 0.00021 21.1 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM82630.1 - 0.00025 21.3 0.0 0.0003 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIM82630.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EIM82630.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EIM82630.1 - 0.0024 17.8 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EIM82630.1 - 0.0026 17.9 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EIM82630.1 - 0.0074 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EIM82630.1 - 0.0089 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIM82630.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIM82630.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIM82630.1 - 0.015 15.0 0.0 0.047 13.4 0.0 1.8 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 EIM82630.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EIM82630.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EIM82630.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EIM82630.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Guanylate_kin PF00625.16 EIM82630.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.7 EIM82630.1 - 0.067 12.2 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EIM82630.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EIM82631.1 - 2.5e-34 118.5 21.3 2.5e-34 118.5 14.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EIM82631.1 - 0.0011 17.5 4.1 0.0011 17.5 2.9 2.7 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EIM82631.1 - 0.0021 17.8 0.7 0.57 10.0 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family Neil1-DNA_bind PF09292.5 EIM82633.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Pyocin_S PF06958.7 EIM82633.1 - 2.8 8.2 10.8 20 5.5 0.1 3.2 3 0 0 3 3 3 0 S-type Pyocin Alpha_GJ PF03229.8 EIM82634.1 - 0.0075 16.5 10.6 0.0075 16.5 7.4 3.7 1 1 2 3 3 3 1 Alphavirus glycoprotein J MNHE PF01899.11 EIM82634.1 - 0.021 14.4 0.2 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit E1-E2_ATPase PF00122.15 EIM82635.1 - 1.4e-25 89.7 0.0 3.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIM82635.1 - 2.5e-25 89.7 0.0 5.3e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM82635.1 - 2.8e-22 80.1 0.0 2e-20 74.1 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EIM82635.1 - 2.5e-17 62.8 0.1 5.5e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 EIM82635.1 - 3.3e-08 33.2 6.7 3.3e-08 33.2 4.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIM82635.1 - 2.1e-05 24.4 0.1 4.7e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIM82635.1 - 5.6e-05 22.5 0.0 0.00016 21.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM82635.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CHCH PF06747.8 EIM82636.1 - 2.2e-06 27.4 4.6 3.4e-06 26.8 3.2 1.3 1 0 0 1 1 1 1 CHCH domain 3Beta_HSD PF01073.14 EIM82637.1 - 4.2e-14 51.9 0.0 5.8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM82637.1 - 2.4e-11 43.5 0.1 5.7e-11 42.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM82637.1 - 1.8e-07 31.3 0.0 3.9e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM82637.1 - 1.1e-05 24.5 0.0 8.6e-05 21.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EIM82637.1 - 0.0041 16.4 0.2 0.056 12.6 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EIM82637.1 - 0.032 14.1 0.1 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Fe-ADH PF00465.14 EIM82638.1 - 2.9e-69 233.4 0.0 3.6e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIM82638.1 - 2.5e-15 56.4 0.0 1.7e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cupin_2 PF07883.6 EIM82639.1 - 1e-11 44.1 0.1 0.00012 21.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EIM82639.1 - 1.7e-05 24.5 0.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.3 EIM82639.1 - 0.0015 18.4 0.3 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_3 PF05899.7 EIM82639.1 - 0.011 15.1 0.0 0.056 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) EutQ PF06249.7 EIM82639.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.17 EIM82639.1 - 0.029 13.7 0.2 0.09 12.2 0.0 1.8 2 0 0 2 2 2 0 Cupin Mito_carr PF00153.22 EIM82640.1 - 2.4e-54 180.9 3.2 7e-19 67.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pilus_CpaD PF09476.5 EIM82640.1 - 0.11 11.9 0.5 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) MFS_1 PF07690.11 EIM82644.1 - 4.5e-16 58.5 50.6 3e-09 36.0 23.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2704 PF10866.3 EIM82644.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) FAD-oxidase_C PF02913.14 EIM82645.1 - 3.6e-52 177.1 0.0 5.9e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIM82645.1 - 4.8e-30 103.8 0.4 1.2e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.11 EIM82651.1 - 3.5e-36 124.6 30.0 3.5e-36 124.6 20.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EIM82652.1 - 1.8e-15 57.5 0.0 3.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM82652.1 - 4.5e-13 49.3 0.0 1.5e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1892 PF08987.5 EIM82652.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) DUF3432 PF11914.3 EIM82652.1 - 0.27 11.3 1.5 0.86 9.6 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3432) Lyase_aromatic PF00221.14 EIM82653.1 - 2.7e-159 530.6 0.8 3.2e-159 530.3 0.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Abhydrolase_6 PF12697.2 EIM82654.1 - 5.2e-23 82.1 0.1 6.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM82654.1 - 0.00027 20.7 0.0 0.00084 19.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM82654.1 - 0.0017 17.9 0.0 0.037 13.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.17 EIM82654.1 - 0.061 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Beta-lactamase PF00144.19 EIM82654.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase adh_short PF00106.20 EIM82656.1 - 2.2e-20 73.2 0.0 4e-20 72.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM82656.1 - 4.5e-09 36.2 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM82656.1 - 0.00075 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EIM82656.1 - 0.0034 17.4 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase QRPTase_C PF01729.14 EIM82656.1 - 0.0036 16.8 0.0 0.0053 16.3 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NAD_binding_10 PF13460.1 EIM82656.1 - 0.0057 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM82656.1 - 0.027 13.9 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIM82656.1 - 0.054 12.4 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF765 PF05570.6 EIM82656.1 - 0.16 11.9 2.6 0.34 10.9 1.8 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Amidohydro_2 PF04909.9 EIM82657.1 - 0.00027 20.5 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Pec_lyase_C PF00544.14 EIM82658.1 - 3.1e-41 141.0 6.8 4.4e-41 140.5 4.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EIM82658.1 - 9e-06 25.5 14.4 0.0033 17.2 9.9 2.3 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EIM82658.1 - 0.01 15.0 6.7 0.021 14.0 4.6 1.7 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) FtsH_ext PF06480.10 EIM82658.1 - 1.6 8.9 4.6 3.3 7.9 0.3 2.4 2 1 0 2 2 2 0 FtsH Extracellular DUF262 PF03235.9 EIM82659.1 - 1.2e-13 51.5 0.1 2.4e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 Tcp11 PF05794.8 EIM82660.1 - 1.3e-13 50.4 0.1 3.1e-12 45.9 0.0 2.6 1 1 0 1 1 1 1 T-complex protein 11 DUF2388 PF09498.5 EIM82660.1 - 0.093 12.3 0.3 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) SGL PF08450.7 EIM82661.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EIM82661.1 - 0.00017 21.4 0.0 0.0028 17.5 0.0 2.8 4 0 0 4 4 4 1 Arylesterase Reg_prop PF07494.6 EIM82661.1 - 0.1 12.6 0.0 4.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.16 EIM82661.1 - 0.16 11.9 3.9 12 6.0 0.0 4.2 5 0 0 5 5 5 0 NHL repeat DBC1 PF14443.1 EIM82662.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 DBC1 Phage_antiter_Q PF06323.6 EIM82662.1 - 0.036 13.4 1.6 1.2 8.4 0.3 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q DDE_3 PF13358.1 EIM82662.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIM82663.1 - 8.6e-11 41.7 0.0 4.1e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease UbiD PF01977.11 EIM82663.1 - 0.16 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Pec_lyase_C PF00544.14 EIM82664.1 - 4.9e-42 143.6 8.0 7e-42 143.1 5.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EIM82664.1 - 0.00029 20.6 15.8 0.034 13.8 11.0 2.3 1 1 0 1 1 1 1 Right handed beta helix region DUF2036 PF09724.4 EIM82665.1 - 2.5e-57 194.4 0.0 2.9e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) FAD_binding_3 PF01494.14 EIM82666.1 - 1.6e-06 27.4 0.0 1.2e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM82666.1 - 0.00087 18.2 0.1 0.0039 16.1 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM82666.1 - 0.0031 17.4 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM82666.1 - 0.051 12.4 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EIM82666.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIM82669.1 - 2.6e-09 36.6 0.0 1e-07 31.3 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIM82669.1 - 1.7e-08 34.3 0.4 4.2e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM82669.1 - 2.8e-06 26.5 6.8 6.2e-06 25.3 0.9 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM82669.1 - 1.7e-05 23.9 1.0 2.8e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIM82669.1 - 3.2e-05 24.2 0.0 0.035 14.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM82669.1 - 6.5e-05 22.8 0.3 0.00012 21.9 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM82669.1 - 0.00031 19.9 0.1 0.0005 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM82669.1 - 0.00064 18.7 0.0 0.0027 16.7 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EIM82669.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIM82669.1 - 0.0074 14.7 0.2 0.012 14.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM82669.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM82669.1 - 0.027 13.3 0.3 0.046 12.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIM82669.1 - 0.029 14.1 0.3 0.073 12.8 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIM82669.1 - 0.068 12.8 0.1 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pacifastin_I PF05375.8 EIM82669.1 - 0.45 10.0 4.7 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Tannase PF07519.6 EIM82670.1 - 4.6e-97 325.6 0.2 8.2e-97 324.8 0.1 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EIM82670.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM82670.1 - 0.08 12.1 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ssl1 PF04056.9 EIM82671.1 - 1.9e-69 233.1 0.0 2.9e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EIM82671.1 - 5.5e-13 49.3 0.0 8.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EIM82671.1 - 0.00024 20.4 6.1 0.55 9.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 Sec7 PF01369.15 EIM82672.1 - 2e-25 89.6 0.0 3.1e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Cation_efflux PF01545.16 EIM82673.1 - 5.7e-47 160.1 5.7 2.6e-41 141.5 3.9 2.5 2 1 0 2 2 2 2 Cation efflux family EspG PF06872.6 EIM82673.1 - 0.016 13.5 0.2 0.025 12.9 0.1 1.1 1 0 0 1 1 1 0 EspG protein F-box-like PF12937.2 EIM82674.1 - 0.011 15.3 0.3 0.03 14.0 0.2 1.8 1 0 0 1 1 1 0 F-box-like APH PF01636.18 EIM82678.1 - 1.4e-16 60.9 0.1 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM82678.1 - 2.2e-05 24.1 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIM82678.1 - 0.0028 17.0 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 EIM82678.1 - 0.072 11.7 0.0 0.6 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.12 EIM82678.1 - 0.1 11.6 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.15 EIM82678.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF4083 PF13314.1 EIM82679.1 - 0.091 12.6 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Peptidase_C14 PF00656.17 EIM82680.1 - 3.7e-17 62.8 0.0 6.7e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DUF498 PF04430.9 EIM82680.1 - 0.031 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DnaJ PF00226.26 EIM82682.1 - 2.1e-10 40.1 0.0 4.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2605 PF10792.4 EIM82682.1 - 0.27 10.9 1.3 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) DUF1771 PF08590.5 EIM82684.1 - 3.7e-18 65.3 5.7 3.7e-18 65.3 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIM82684.1 - 9.1e-14 51.4 0.1 1.5e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Smr domain Smr PF01713.16 EIM82685.1 - 1.9e-09 37.5 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EIM82685.1 - 0.00021 21.2 0.3 0.00021 21.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) F-box-like PF12937.2 EIM82687.1 - 2.9e-07 30.1 0.0 5.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM82687.1 - 0.0028 17.2 0.2 2.4 7.9 0.0 2.9 2 0 0 2 2 2 2 F-box domain p450 PF00067.17 EIM82688.1 - 7.1e-67 225.9 0.0 9.4e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.1 EIM82689.1 - 1.2e-06 28.8 0.0 1.9e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM82689.1 - 0.00022 20.9 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1771 PF08590.5 EIM82690.1 - 6.3e-19 67.7 4.0 6.3e-19 67.7 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIM82690.1 - 2.5e-05 24.3 0.1 8.1e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EIM82692.1 - 4.5e-23 81.0 5.7 1.3e-22 79.5 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIM82692.1 - 1.1e-15 57.5 0.2 3.8e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 Smr domain Ribosomal_S5 PF00333.15 EIM82693.1 - 7e-28 96.1 1.0 7e-28 96.1 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIM82693.1 - 4e-22 77.2 0.1 6.7e-22 76.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 EIM82693.1 - 0.87 10.0 11.6 1.7 9.1 8.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ODC_AZ PF02100.12 EIM82694.1 - 7.9e-17 60.7 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme CN_hydrolase PF00795.17 EIM82695.1 - 2.7e-36 124.6 0.0 3.5e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RNA_pol_A_bac PF01000.21 EIM82696.1 - 2.6e-30 104.8 0.1 4.3e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIM82696.1 - 2e-15 55.6 0.0 3.2e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EIM82696.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF22 6PF2K PF01591.13 EIM82696.1 - 0.015 14.3 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Corona_6B_7B PF03262.8 EIM82696.1 - 0.054 12.7 0.2 0.086 12.0 0.2 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein MS_channel PF00924.13 EIM82698.1 - 1e-11 44.5 9.9 7.3e-11 41.7 6.9 2.1 1 1 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIM82698.1 - 0.0041 16.3 0.3 0.011 14.9 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EIM82698.1 - 0.022 14.8 0.3 0.058 13.5 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EIM82698.1 - 0.022 14.5 0.2 0.064 13.1 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 EIM82698.1 - 0.031 13.6 0.2 0.073 12.4 0.2 1.5 1 0 0 1 1 1 0 EF hand Pkinase PF00069.20 EIM82699.1 - 4.3e-56 189.9 0.0 3.5e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82699.1 - 6.4e-25 87.7 0.0 1.9e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM82699.1 - 0.0012 17.8 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM82699.1 - 0.004 16.9 0.5 0.012 15.3 0.4 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EIM82699.1 - 0.02 15.3 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EIM82699.1 - 0.029 13.1 0.1 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EIM82699.1 - 0.29 9.9 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Homeobox PF00046.24 EIM82700.1 - 6.6e-17 60.8 3.5 1.9e-16 59.4 2.4 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM82700.1 - 0.0011 18.6 0.2 0.0039 16.8 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain KRTAP7 PF15034.1 EIM82700.1 - 0.077 13.6 0.6 0.077 13.6 0.4 2.2 2 0 0 2 2 2 0 KRTAP type 7 family ABC_tran PF00005.22 EIM82701.1 - 8.3e-48 162.1 0.7 2.1e-28 99.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM82701.1 - 4.2e-15 56.4 1.8 0.0096 15.9 0.1 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EIM82701.1 - 2.3e-11 43.3 0.0 0.00063 19.0 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EIM82701.1 - 1.4e-08 34.2 0.0 3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miro PF08477.8 EIM82701.1 - 1.1e-07 32.3 0.0 0.018 15.5 0.0 3.2 3 0 0 3 3 3 2 Miro-like protein AAA_17 PF13207.1 EIM82701.1 - 2.6e-07 31.4 0.0 0.044 14.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EIM82701.1 - 1.3e-06 28.3 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIM82701.1 - 4.4e-06 26.1 2.8 0.06 12.8 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM82701.1 - 1.3e-05 25.3 0.1 0.066 13.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EIM82701.1 - 1.8e-05 24.7 0.0 0.098 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM82701.1 - 2.3e-05 24.4 0.1 3.6 7.5 0.0 4.6 4 0 0 4 4 4 0 AAA ATPase domain DUF87 PF01935.12 EIM82701.1 - 2.9e-05 24.0 0.2 0.17 11.6 0.0 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EIM82701.1 - 5.7e-05 23.5 0.2 0.1 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIM82701.1 - 7.6e-05 22.2 0.7 0.26 10.6 0.1 2.8 3 0 0 3 3 2 2 AAA-like domain MobB PF03205.9 EIM82701.1 - 9e-05 22.2 0.0 0.43 10.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EIM82701.1 - 0.00015 21.2 0.0 1.6 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EIM82701.1 - 0.00015 20.9 0.0 0.062 12.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EIM82701.1 - 0.00015 21.6 0.0 0.54 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EIM82701.1 - 0.00028 21.1 0.0 0.96 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain HEAT PF02985.17 EIM82701.1 - 0.00029 20.6 0.6 5.5 7.3 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat ArgK PF03308.11 EIM82701.1 - 0.00039 19.2 0.8 0.16 10.6 0.1 2.3 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EIM82701.1 - 0.00069 19.3 0.9 0.098 12.3 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_14 PF13173.1 EIM82701.1 - 0.0013 18.5 0.3 2.6 7.9 0.0 3.3 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EIM82701.1 - 0.0024 18.0 0.1 5.1 7.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 EIM82701.1 - 0.0053 16.5 0.0 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 EIM82701.1 - 0.0066 16.3 0.0 1.7 8.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EIM82701.1 - 0.0069 15.4 0.0 15 4.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.1 EIM82701.1 - 0.012 14.0 0.0 2.4 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIM82701.1 - 0.014 15.1 0.1 5.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Archaeal ATPase ATP_bind_1 PF03029.12 EIM82701.1 - 0.032 13.7 0.5 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.16 EIM82701.1 - 0.034 13.5 0.3 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 EIM82701.1 - 0.047 13.1 0.2 7.9 5.8 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIM82701.1 - 0.054 12.9 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.1 EIM82701.1 - 0.055 13.9 2.7 8.8 6.9 0.2 4.0 2 1 2 4 4 4 0 HEAT-like repeat FtsK_SpoIIIE PF01580.13 EIM82701.1 - 0.066 12.6 0.3 0.64 9.4 0.0 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA PF00004.24 EIM82701.1 - 0.084 13.0 0.2 6 7.0 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 EIM82701.1 - 0.084 12.2 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EIM82701.1 - 0.11 11.6 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Tudor-knot PF11717.3 EIM82701.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AAA_30 PF13604.1 EIM82701.1 - 0.21 11.1 3.9 11 5.5 0.0 3.5 5 0 0 5 5 3 0 AAA domain DUF3584 PF12128.3 EIM82701.1 - 0.49 7.6 2.9 3 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_5 PF07728.9 EIM82701.1 - 0.53 10.0 2.1 33 4.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Adaptin_N PF01602.15 EIM82701.1 - 0.83 7.8 1.8 12 4.0 1.2 2.3 1 1 1 2 2 2 0 Adaptin N terminal region p450 PF00067.17 EIM82702.1 - 7.1e-60 202.8 0.0 2.5e-59 201.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Sec31 PF11549.3 EIM82702.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 ABC1 PF03109.11 EIM82704.1 - 1.4e-33 115.3 0.0 2.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EIM82704.1 - 0.00038 19.8 0.1 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EIM82704.1 - 0.11 11.6 0.0 0.54 9.3 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain RabGAP-TBC PF00566.13 EIM82705.1 - 3.6e-52 176.9 0.1 6.8e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC144C PF14915.1 EIM82705.1 - 0.038 12.9 5.7 0.062 12.2 4.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Cep57_CLD_2 PF14197.1 EIM82705.1 - 0.18 11.7 7.0 0.37 10.7 4.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIVA PF05103.8 EIM82705.1 - 0.22 11.5 3.5 1.4 9.0 1.5 2.3 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.10 EIM82705.1 - 0.64 9.5 3.4 6.9 6.2 0.3 2.5 1 1 1 2 2 2 0 Septum formation initiator Scaffolding_pro PF11418.3 EIM82705.1 - 1.6 9.0 4.9 2.9 8.2 0.1 3.0 3 1 0 4 4 4 0 Phi29 scaffolding protein PC4 PF02229.11 EIM82706.1 - 2.7e-21 74.5 0.2 4.7e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) TFIIE-A_C-term PF11521.3 EIM82706.1 - 0.058 13.3 5.7 0.13 12.2 4.0 1.6 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha YscJ_FliF_C PF08345.6 EIM82706.1 - 0.063 13.2 3.3 0.1 12.5 2.3 1.4 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal Pox_Ag35 PF03286.9 EIM82706.1 - 0.071 12.6 7.4 0.093 12.2 5.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pap_E4 PF02711.9 EIM82706.1 - 0.12 13.1 0.9 0.22 12.3 0.6 1.4 1 0 0 1 1 1 0 E4 protein VirionAssem_T7 PF11653.3 EIM82706.1 - 0.14 12.9 5.5 0.28 11.9 3.8 1.5 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein CDC45 PF02724.9 EIM82706.1 - 0.24 9.4 3.0 0.27 9.2 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EIM82706.1 - 0.77 9.4 2.8 1 9.0 1.9 1.3 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 EIM82706.1 - 9.2 6.0 8.7 12 5.7 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HECT PF00632.20 EIM82707.1 - 1.1e-89 300.7 0.0 1.8e-89 300.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EIM82707.1 - 4.7e-87 292.1 0.0 4.7e-87 292.1 0.0 4.8 5 2 1 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EIM82707.1 - 1.5e-63 215.1 0.0 1.5e-63 215.1 0.0 3.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EIM82707.1 - 7.6e-31 106.2 7.6 7.6e-31 106.2 5.3 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EIM82707.1 - 3.8e-07 29.7 0.0 1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF2304 PF10066.4 EIM82707.1 - 0.62 9.9 0.0 1.5 8.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Peptidase_C1_2 PF03051.10 EIM82709.1 - 1.2e-156 521.6 0.0 1.5e-156 521.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EIM82709.1 - 1.7e-08 34.6 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Tautomerase PF01361.16 EIM82709.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme F-box PF00646.28 EIM82710.1 - 3.8e-05 23.2 0.9 8.6e-05 22.0 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM82710.1 - 0.13 12.0 3.1 0.1 12.3 0.5 2.0 2 0 0 2 2 2 0 F-box-like Fib_alpha PF08702.5 EIM82711.1 - 0.0021 18.1 6.9 0.048 13.7 0.9 2.4 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family MitMem_reg PF13012.1 EIM82711.1 - 0.0045 17.0 3.5 0.15 12.1 0.1 2.7 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function CHASE3 PF05227.8 EIM82711.1 - 0.017 14.7 5.0 2 8.1 0.4 2.6 2 0 0 2 2 2 0 CHASE3 domain Guanylin PF02058.10 EIM82711.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Guanylin precursor EzrA PF06160.7 EIM82711.1 - 0.13 10.4 9.1 0.043 11.9 1.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA XhlA PF10779.4 EIM82711.1 - 0.18 11.7 3.0 1.8 8.5 1.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA AAA_13 PF13166.1 EIM82711.1 - 0.19 10.1 8.2 0.79 8.1 5.7 1.7 1 1 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 EIM82711.1 - 0.38 10.1 3.9 0.79 9.0 0.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FliJ PF02050.11 EIM82711.1 - 0.52 10.3 11.2 0.53 10.3 0.8 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein CDC37_N PF03234.9 EIM82711.1 - 0.57 10.4 6.2 4.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding OmpH PF03938.9 EIM82711.1 - 0.93 9.4 8.0 0.85 9.5 0.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EIM82711.1 - 1.4 8.4 7.4 2.5 7.6 0.5 2.3 2 0 0 2 2 2 0 IncA protein DUF4407 PF14362.1 EIM82711.1 - 1.5 7.7 6.3 0.64 8.9 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.8 EIM82711.1 - 4.7 7.1 10.5 0.1 12.5 1.7 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EIM82711.1 - 5.1 6.2 11.7 1.1 8.4 1.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Use1 PF09753.4 EIM82711.1 - 9.5 5.5 9.2 2.2 7.6 0.8 2.3 1 1 1 2 2 2 0 Membrane fusion protein Use1 TBPIP PF07106.8 EIM82711.1 - 9.9 5.6 10.4 13 5.3 1.0 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PARP PF00644.15 EIM82712.1 - 3.1e-15 56.1 0.0 6.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain TPR_11 PF13414.1 EIM82713.1 - 5.6e-12 45.1 15.2 2e-06 27.3 1.8 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIM82713.1 - 7.6e-10 37.9 7.7 3e-07 29.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82713.1 - 4.5e-06 26.1 0.3 4.5e-06 26.1 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM82713.1 - 0.0033 17.2 2.8 0.035 13.9 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM82713.1 - 0.0062 17.1 10.2 0.49 11.1 0.5 3.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82713.1 - 0.0068 16.1 6.4 0.013 15.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82713.1 - 0.023 14.6 3.3 0.023 14.6 2.3 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM82713.1 - 0.031 14.7 0.8 0.031 14.7 0.5 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82713.1 - 0.058 14.0 0.8 0.058 14.0 0.5 3.5 4 2 1 5 5 3 0 Tetratricopeptide repeat UIM PF02809.15 EIM82713.1 - 0.07 12.7 1.8 0.19 11.4 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Apc3 PF12895.2 EIM82713.1 - 0.21 11.7 5.7 0.16 12.0 1.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Usp PF00582.21 EIM82713.1 - 0.7 10.0 0.1 0.7 10.0 0.0 2.0 2 1 0 2 2 2 0 Universal stress protein family p450 PF00067.17 EIM82714.1 - 2.6e-60 204.2 0.0 3.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Palm_thioest PF02089.10 EIM82714.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Glyco_hydro_18 PF00704.23 EIM82717.1 - 6.7e-93 311.8 0.9 8.1e-93 311.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_8 PF01501.15 EIM82719.1 - 5e-24 85.0 0.0 9.9e-24 84.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 EIM82719.1 - 1.7e-14 54.5 0.1 1e-13 52.0 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain Amidohydro_1 PF01979.15 EIM82721.1 - 1.3e-06 28.3 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIM82721.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM82721.1 - 0.00029 20.1 0.0 0.00034 19.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family NTP_transf_2 PF01909.18 EIM82721.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain ChAPs PF09295.5 EIM82722.1 - 0.0033 16.2 0.5 0.83 8.3 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.1 EIM82722.1 - 0.0092 16.6 7.5 0.0097 16.5 2.5 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM82722.1 - 0.017 14.7 2.3 0.018 14.6 0.4 1.8 1 1 1 2 2 2 0 TPR repeat TPR_9 PF13371.1 EIM82722.1 - 0.041 13.7 1.2 0.086 12.7 0.6 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82722.1 - 0.047 13.6 2.6 17 5.5 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82722.1 - 3.5 8.5 9.2 7.2 7.5 3.2 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM82723.1 - 1.3e-48 162.5 10.1 3.2e-10 39.4 0.0 13.2 11 3 2 14 14 14 9 TPR repeat TPR_16 PF13432.1 EIM82723.1 - 2.7e-28 97.9 34.3 3.9e-07 30.5 0.2 12.8 11 3 3 14 14 13 6 Tetratricopeptide repeat TPR_2 PF07719.12 EIM82723.1 - 2.9e-28 95.4 20.7 0.0042 16.8 0.0 16.8 20 0 0 20 20 18 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82723.1 - 1.9e-27 93.1 15.0 0.0021 18.1 0.4 12.9 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82723.1 - 5.1e-26 89.1 6.9 0.00066 19.1 0.1 13.0 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82723.1 - 5.3e-24 82.5 23.3 0.00054 20.3 0.1 15.3 13 3 4 17 17 15 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIM82723.1 - 1.1e-21 76.9 14.7 0.0019 18.5 0.2 10.4 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82723.1 - 1.9e-19 67.9 13.8 0.021 14.5 0.1 14.4 15 3 2 17 17 17 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82723.1 - 1.8e-17 63.0 21.5 0.046 13.6 0.2 12.2 7 5 8 15 15 15 5 Tetratricopeptide repeat Apc3 PF12895.2 EIM82723.1 - 8.5e-14 51.4 4.7 0.019 15.0 0.0 8.2 8 1 0 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM82723.1 - 1e-12 46.8 3.0 1.4 8.9 0.0 9.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM82723.1 - 9.8e-10 38.1 15.9 0.024 14.4 0.0 7.7 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIM82723.1 - 2.5e-07 30.7 22.1 3 8.5 0.0 11.3 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIM82723.1 - 0.008 16.2 9.2 0.24 11.5 0.0 6.5 6 2 1 7 7 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EIM82723.1 - 0.033 12.9 0.4 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region NARP1 PF12569.3 EIM82723.1 - 0.092 11.4 3.7 2.8 6.5 0.4 3.8 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EIM82723.1 - 8.8 7.0 27.9 0.49 10.9 0.3 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.15 EIM82724.1 - 6.9e-26 91.0 0.0 1.7e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 EIM82724.1 - 6.6e-16 59.0 0.0 1.5e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EIM82725.1 - 4.9e-41 140.7 0.0 8.2e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.21 EIM82725.1 - 7e-19 68.1 0.5 4.6e-17 62.2 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 3Beta_HSD PF01073.14 EIM82725.1 - 1e-18 67.0 0.0 1.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tranf_2_3 PF13641.1 EIM82725.1 - 3.5e-10 40.0 0.0 1.9e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_10 PF13460.1 EIM82725.1 - 5.5e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Glyco_tranf_2_2 PF10111.4 EIM82725.1 - 7.4e-07 28.5 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NAD_binding_4 PF07993.7 EIM82725.1 - 7.4e-07 28.3 0.0 0.0005 19.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EIM82725.1 - 0.00057 18.8 0.0 0.13 11.0 0.0 2.9 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM82725.1 - 0.00098 18.0 0.0 0.0021 16.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EIM82725.1 - 0.001 19.0 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 1 1 TrkA-N domain adh_short PF00106.20 EIM82725.1 - 0.0025 17.7 0.0 0.0098 15.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Gluconate_2-dh3 PF13618.1 EIM82725.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Glyco_tranf_2_5 PF13712.1 EIM82725.1 - 0.055 12.7 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family KR PF08659.5 EIM82725.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EIM82725.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family LETM1 PF07766.8 EIM82728.1 - 6e-30 104.1 0.5 1.3e-17 63.6 0.2 2.1 1 1 1 2 2 2 2 LETM1-like protein p450 PF00067.17 EIM82729.1 - 9.5e-75 251.8 0.0 1.4e-74 251.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YesK PF14150.1 EIM82730.1 - 0.0014 18.7 2.2 0.0014 18.7 1.5 2.7 3 1 0 3 3 3 1 YesK-like protein Peptidase_M14 PF00246.19 EIM82731.1 - 3.3e-22 79.4 0.1 4.8e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 EIM82731.1 - 0.00013 20.9 0.5 0.00022 20.2 0.3 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_11 PF13414.1 EIM82732.1 - 2.3e-16 59.1 9.2 3.9e-09 36.0 0.5 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIM82732.1 - 1.9e-11 42.9 5.5 0.0001 21.9 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82732.1 - 2.6e-10 39.4 4.9 0.0001 21.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM82732.1 - 1.8e-07 31.6 6.1 1.8e-07 31.6 4.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82732.1 - 8.7e-06 25.9 11.9 0.0012 19.3 1.9 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM82732.1 - 2.1e-05 24.7 4.5 0.00073 19.8 2.2 2.8 2 2 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM82732.1 - 0.00086 19.3 0.5 0.0019 18.2 0.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM82732.1 - 0.0012 18.4 0.8 0.022 14.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82732.1 - 0.0035 17.2 4.1 0.0078 16.1 1.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM82732.1 - 0.0097 15.7 2.2 0.57 10.0 1.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82732.1 - 0.015 15.4 3.4 0.2 11.9 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EIM82732.1 - 0.044 12.9 0.1 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit RLL PF10036.4 EIM82732.1 - 0.053 12.9 0.3 0.095 12.1 0.2 1.4 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein TPR_7 PF13176.1 EIM82732.1 - 0.1 12.4 2.7 6.5 6.8 0.1 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_PrkA PF08298.6 EIM82732.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TPR_6 PF13174.1 EIM82732.1 - 0.67 10.5 8.4 0.53 10.8 0.3 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Aa_trans PF01490.13 EIM82733.1 - 6.4e-64 215.9 31.7 1e-63 215.2 21.9 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein tRNA-synt_1 PF00133.17 EIM82734.1 - 1.2e-221 736.9 0.0 2.1e-220 732.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIM82734.1 - 7.6e-28 97.1 0.1 1.5e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIM82734.1 - 2.9e-17 62.3 0.5 1.4e-05 23.9 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIM82734.1 - 0.029 13.4 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain EXS PF03124.9 EIM82735.1 - 4.4e-73 246.2 0.0 8.6e-71 238.7 0.0 2.5 1 1 0 1 1 1 1 EXS family CHDCT2 PF08074.6 EIM82735.1 - 0.055 13.2 0.3 0.09 12.5 0.2 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain GHMP_kinases_N PF00288.21 EIM82736.1 - 1.6e-10 40.8 1.7 4.5e-10 39.4 1.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIM82736.1 - 8e-06 25.9 0.0 3.1e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 GHMP kinases C terminal Phage_AlpA PF05930.7 EIM82737.1 - 0.12 12.1 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) CPSase_sm_chain PF00988.17 EIM82738.1 - 1.6e-44 150.6 0.0 2.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIM82738.1 - 6.4e-35 120.3 0.0 9.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIM82738.1 - 2.9e-08 33.4 0.1 1.7e-07 30.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EIM82738.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Metallophos PF00149.23 EIM82739.1 - 2e-10 40.3 0.7 3e-09 36.5 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM82739.1 - 5.9e-07 29.4 0.0 1.4e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ADH_zinc_N PF00107.21 EIM82740.1 - 2.2e-18 66.0 0.0 3.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82740.1 - 0.00031 21.6 0.0 0.00056 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM82741.1 - 5.3e-20 71.2 0.0 8.5e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82741.1 - 6.3e-06 27.1 0.0 1.3e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BAG PF02179.11 EIM82742.1 - 1.8e-12 47.2 0.0 1.6e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 BAG domain ubiquitin PF00240.18 EIM82742.1 - 1.3e-08 34.1 0.0 3.4e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIM82742.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Pkinase PF00069.20 EIM82743.1 - 1.8e-52 178.0 0.0 2.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82743.1 - 4.8e-36 124.1 0.0 6.4e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM82743.1 - 5.2e-08 32.2 0.0 8.2e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM82743.1 - 0.0044 16.7 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIM82743.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TLV_coat PF00429.14 EIM82745.1 - 0.14 10.6 0.1 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) RVT_3 PF13456.1 EIM82746.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like ADH_zinc_N PF00107.21 EIM82750.1 - 2.6e-21 75.5 0.0 4.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM82750.1 - 0.00074 20.4 0.0 0.0022 18.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EIM82750.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HMG_box PF00505.14 EIM82751.1 - 5e-06 26.7 0.1 2e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM82751.1 - 0.12 12.7 0.3 0.47 10.8 0.2 1.9 1 1 0 1 1 1 0 HMG-box domain F-box PF00646.28 EIM82753.1 - 1.1e-06 28.1 0.0 2.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM82753.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.7 EIM82754.1 - 1.1e-117 393.7 0.3 1.4e-117 393.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Smr PF01713.16 EIM82756.1 - 3.5e-08 33.5 0.0 4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Smr domain FAM195 PF14799.1 EIM82758.1 - 1.3e-06 28.2 0.5 0.0093 15.8 0.0 2.2 1 1 1 2 2 2 2 FAM195 family DUF2781 PF10914.3 EIM82758.1 - 0.43 10.3 1.8 2.9 7.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) DUF3824 PF12868.2 EIM82758.1 - 0.52 11.2 5.8 10 7.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) FAM195 PF14799.1 EIM82759.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM195 family Pkinase PF00069.20 EIM82760.1 - 1.7e-07 30.6 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIM82760.1 - 0.00029 19.9 0.1 0.00073 18.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIM82760.1 - 0.0019 17.3 0.0 0.0042 16.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FAM195 PF14799.1 EIM82760.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 FAM195 family Pept_tRNA_hydro PF01195.14 EIM82761.1 - 3e-40 137.6 0.0 3.6e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase HlyIII PF03006.15 EIM82762.1 - 1.8e-37 128.8 21.1 4.1e-37 127.7 14.5 1.6 2 0 0 2 2 2 1 Haemolysin-III related Mucin PF01456.12 EIM82762.1 - 0.21 11.3 10.0 0.41 10.3 6.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIID_20kDa PF03847.8 EIM82763.1 - 1.2e-28 99.1 0.1 2.6e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EIM82763.1 - 0.00068 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF515 PF04415.7 EIM82763.1 - 0.05 11.8 1.4 0.081 11.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BLVR PF06375.6 EIM82764.1 - 1.3 8.8 9.5 2.5 7.8 6.6 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) AFG1_ATPase PF03969.11 EIM82765.1 - 5.5e-50 170.1 0.0 4.6e-44 150.6 0.0 3.2 3 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 EIM82765.1 - 5.1e-05 23.3 0.1 0.00027 20.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM82765.1 - 5.4e-05 23.3 0.0 0.0012 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIM82765.1 - 0.0021 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIM82765.1 - 0.0025 16.9 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EIM82765.1 - 0.0061 15.9 0.1 1.7 8.0 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.1 EIM82765.1 - 0.0076 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EIM82765.1 - 0.0079 15.9 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 EIM82765.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EIM82765.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIM82765.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIM82765.1 - 0.12 11.7 0.1 0.29 10.5 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EIM82765.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter HSP20 PF00011.16 EIM82767.1 - 0.016 15.0 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Git3 PF11710.3 EIM82772.1 - 3.8e-12 46.2 5.5 9.5e-12 44.8 3.8 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF4181 PF13789.1 EIM82772.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) DUF3669 PF12417.3 EIM82773.1 - 1e-10 41.2 0.4 1.8e-10 40.3 0.3 1.3 1 0 0 1 1 1 1 Zinc finger protein Antimicrobial10 PF08105.6 EIM82774.1 - 0.048 13.2 0.2 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Metchnikowin family Kunitz_BPTI PF00014.18 EIM82774.1 - 0.12 12.6 2.4 0.18 12.0 1.6 1.3 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Ribosomal_L39 PF00832.15 EIM82775.1 - 1.7e-22 78.5 9.2 2e-22 78.3 6.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein FKBP_C PF00254.23 EIM82776.1 - 8.3e-32 109.0 0.0 1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SynMuv_product PF06047.6 EIM82777.1 - 9e-42 141.0 3.2 9e-42 141.0 2.2 2.9 2 1 1 3 3 3 1 Ras-induced vulval development antagonist Pkinase PF00069.20 EIM82778.1 - 3.3e-23 82.1 0.0 6.3e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82778.1 - 7.1e-14 51.4 0.0 4.4e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EIM82778.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIM82778.1 - 0.0037 16.3 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM82778.1 - 0.0042 16.8 0.3 0.014 15.1 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF605 PF04652.11 EIM82778.1 - 2 7.7 9.5 2.9 7.1 6.6 1.3 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EIM82779.1 - 2.4e-50 171.1 0.0 3.5e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82779.1 - 3.2e-28 98.5 0.0 4.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM82779.1 - 1.9e-05 23.8 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM82779.1 - 0.00046 19.3 0.0 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM82779.1 - 0.052 13.2 0.0 0.29 10.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIM82779.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HMG_box PF00505.14 EIM82781.1 - 0.001 19.2 0.9 0.0048 17.1 0.6 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box Malate_synthase PF01274.17 EIM82782.1 - 6.5e-199 661.2 0.0 7.4e-199 661.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EIM82782.1 - 0.096 11.5 0.0 0.52 9.1 0.0 2.0 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family CHD5 PF04420.9 EIM82783.1 - 3.2e-47 160.1 2.3 4.1e-47 159.8 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein Vma12 PF11712.3 EIM82783.1 - 0.017 14.8 0.2 0.017 14.8 0.1 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HMG_box PF00505.14 EIM82784.1 - 2.3e-08 34.1 5.9 5.1e-08 33.0 4.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM82784.1 - 0.0011 19.2 3.7 0.0011 19.2 2.6 1.9 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EIM82786.1 - 5.3e-13 49.0 0.1 7.7e-13 48.5 0.1 1.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM82786.1 - 0.00086 19.6 1.0 0.001 19.3 0.7 1.3 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EIM82787.1 - 4.8e-09 36.3 2.5 4.8e-09 36.3 1.8 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box ATP-synt_DE_N PF02823.11 EIM82788.1 - 2.3e-20 72.1 0.1 3.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Peptidase_S64 PF08192.6 EIM82789.1 - 0.014 13.7 0.0 0.024 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 OsmC PF02566.14 EIM82790.1 - 1.3e-14 54.1 0.0 2.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein 2OG-FeII_Oxy_2 PF13532.1 EIM82791.1 - 1.1e-16 61.2 0.1 2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EIM82792.1 - 4.7e-05 22.6 0.0 6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82792.1 - 0.065 12.2 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Homeobox PF00046.24 EIM82794.1 - 1e-17 63.4 2.0 1.9e-17 62.6 1.4 1.5 1 0 0 1 1 1 1 Homeobox domain zf-TRAF PF02176.13 EIM82795.1 - 4e-09 36.7 17.0 0.00031 21.0 2.4 3.9 1 1 2 3 3 3 2 TRAF-type zinc finger zf-Nse PF11789.3 EIM82795.1 - 3.9e-07 29.4 7.0 3.9e-07 29.4 4.8 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EIM82795.1 - 2.8e-06 27.0 11.8 2.8e-06 27.0 8.2 3.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM82795.1 - 0.00015 21.3 12.3 0.00015 21.3 8.5 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM82795.1 - 0.00028 20.5 10.0 0.00028 20.5 6.9 3.4 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM82795.1 - 0.00049 20.0 11.5 0.00049 20.0 7.9 3.7 2 1 3 5 5 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIM82795.1 - 0.0024 17.6 3.6 0.0086 15.8 2.5 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EIM82795.1 - 0.0048 16.5 9.2 0.0048 16.5 6.4 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM82795.1 - 0.014 15.0 9.1 0.052 13.2 6.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EIM82795.1 - 0.049 13.2 0.6 0.049 13.2 0.5 3.1 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Sina PF03145.11 EIM82795.1 - 0.16 11.6 13.4 0.63 9.6 0.1 3.5 2 1 2 4 4 4 0 Seven in absentia protein family DEAD PF00270.24 EIM82796.1 - 4e-36 124.0 0.0 6.7e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIM82796.1 - 3.1e-20 71.4 0.1 6.5e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIM82796.1 - 2.6e-15 56.0 0.0 5.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM82796.1 - 0.0024 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Laminin_I PF06008.9 EIM82798.1 - 0.0037 16.6 5.3 0.0037 16.6 3.6 1.7 1 1 0 1 1 1 1 Laminin Domain I Reo_sigmaC PF04582.7 EIM82798.1 - 0.0048 16.1 2.1 0.0091 15.2 1.5 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIM82798.1 - 0.011 15.4 0.5 0.011 15.4 0.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1759 PF03564.10 EIM82798.1 - 0.018 14.8 1.5 0.035 13.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) FliJ PF02050.11 EIM82798.1 - 0.019 15.0 3.1 0.019 15.0 2.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Atg14 PF10186.4 EIM82798.1 - 0.037 12.9 13.6 0.39 9.6 9.8 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 EIM82798.1 - 0.039 14.2 9.4 1.2 9.4 2.5 3.2 2 1 0 3 3 3 0 Spectrin repeat MscS_porin PF12795.2 EIM82798.1 - 0.11 11.7 11.9 0.18 11.0 8.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EIM82798.1 - 0.19 10.3 10.6 0.39 9.3 7.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.9 EIM82798.1 - 0.67 9.5 5.3 0.58 9.7 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GAGA_bind PF06217.7 EIM82798.1 - 0.68 9.8 5.0 1.1 9.1 3.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family APG6 PF04111.7 EIM82798.1 - 1.6 7.6 10.3 2.3 7.2 7.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EIM82798.1 - 4.4 6.8 14.4 1.2 8.7 4.2 2.3 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EIM82798.1 - 7.7 6.3 16.2 15 5.4 2.3 2.7 2 1 1 3 3 3 0 Tropomyosin like CHASE3 PF05227.8 EIM82799.1 - 0.0058 16.3 4.0 0.1 12.2 1.0 2.4 2 0 0 2 2 2 2 CHASE3 domain Sugarporin_N PF11471.3 EIM82799.1 - 0.028 14.0 0.3 0.028 14.0 0.2 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension HSP70 PF00012.15 EIM82800.1 - 0.25 9.2 0.1 0.77 7.5 0.0 1.7 2 0 0 2 2 2 0 Hsp70 protein Bax1-I PF01027.15 EIM82801.1 - 2.8e-49 167.5 22.7 3.2e-49 167.3 15.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EIM82801.1 - 0.051 12.9 11.4 0.23 10.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Med3 PF11593.3 EIM82802.1 - 0.24 10.5 2.5 0.3 10.2 1.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CMAS PF02353.15 EIM82804.1 - 3.2e-32 111.6 0.1 5.5e-31 107.6 0.1 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EIM82804.1 - 4e-13 49.2 0.0 7.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM82804.1 - 1e-11 45.1 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM82804.1 - 6.1e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM82804.1 - 6.5e-11 42.8 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM82804.1 - 1.1e-09 38.5 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM82804.1 - 1.5e-07 30.9 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIM82804.1 - 6.5e-07 29.6 0.0 2.2e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM82804.1 - 8.6e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EIM82804.1 - 0.00057 19.1 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EIM82804.1 - 0.003 16.9 0.0 0.007 15.7 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.6 EIM82804.1 - 0.0031 16.2 0.0 0.0046 15.7 0.0 1.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.14 EIM82804.1 - 0.033 13.7 0.0 0.096 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIM82804.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 EIM82804.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.13 EIM82804.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pro-kuma_activ PF09286.6 EIM82805.1 - 5.1e-46 156.2 0.0 1.4e-45 154.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM82805.1 - 0.0014 17.7 3.0 0.0026 16.9 2.0 1.3 1 0 0 1 1 1 1 Subtilase family CFEM PF05730.6 EIM82806.1 - 8e-08 31.9 9.6 1.1e-07 31.5 6.7 1.2 1 0 0 1 1 1 1 CFEM domain DUF4006 PF13179.1 EIM82806.1 - 0.047 13.2 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF2413 PF10310.4 EIM82807.1 - 1.3 7.7 6.4 1.8 7.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) FLO_LFY PF01698.11 EIM82807.1 - 2.4 6.9 10.5 3.5 6.3 7.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Epimerase PF01370.16 EIM82810.1 - 3e-17 62.8 0.1 5e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM82810.1 - 3.3e-16 58.8 0.0 4.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM82810.1 - 2.2e-15 57.1 0.2 3.9e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM82810.1 - 5.6e-12 45.1 0.0 3.8e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIM82810.1 - 4.3e-08 33.2 0.1 4.3e-08 33.2 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EIM82810.1 - 4.6e-06 26.4 0.6 1.2e-05 25.0 0.4 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EIM82810.1 - 1.3e-05 24.5 0.4 2.6e-05 23.5 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family MDM31_MDM32 PF08118.6 EIM82811.1 - 6.7e-133 443.7 5.8 2.4e-131 438.6 4.0 2.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Cupin_5 PF06172.6 EIM82812.1 - 6.9e-24 84.3 0.0 8.5e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) FAT PF02259.18 EIM82813.1 - 1.3e-64 218.4 9.2 1.9e-64 217.8 5.7 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIM82813.1 - 3.4e-15 56.1 0.4 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TPR_11 PF13414.1 EIM82813.1 - 0.013 15.1 0.7 0.3 10.7 0.1 3.2 2 0 0 2 2 2 0 TPR repeat RIX1 PF08167.7 EIM82813.1 - 1.3 8.7 14.5 0.26 10.9 0.1 5.6 7 0 0 7 7 7 0 rRNA processing/ribosome biogenesis TFIIA PF03153.8 EIM82813.1 - 4.2 7.1 4.1 7.3 6.3 2.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KTI12 PF08433.5 EIM82814.1 - 6.6e-79 264.8 0.0 7.4e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIM82814.1 - 6.3e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM82814.1 - 0.0077 16.5 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM82814.1 - 0.021 15.6 0.0 0.042 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain RhoGAP PF00620.22 EIM82815.1 - 1.2e-43 148.3 0.1 2.9e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EIM82815.1 - 3e-13 49.5 33.1 5e-08 32.8 7.4 3.1 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 EIM82815.1 - 3.1e-06 26.8 7.3 3.1e-06 26.8 5.1 4.0 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF972 PF06156.8 EIM82815.1 - 1 9.7 6.3 2.5 8.4 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Cytochrome_C7 PF14522.1 EIM82815.1 - 7.2 6.3 27.0 8.1 6.1 7.9 3.0 1 1 2 3 3 3 0 Cytochrome c7 Chitin_synth_1 PF01644.12 EIM82816.1 - 1e-78 262.7 0.1 1.8e-78 261.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIM82816.1 - 1.4e-25 88.7 0.0 3.4e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIM82816.1 - 1.6e-23 82.9 3.3 7.5e-19 67.4 0.0 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM82816.1 - 1.5e-11 44.3 0.3 1.5e-11 44.3 0.2 3.3 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM82816.1 - 3.7e-06 26.9 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Aa_trans PF01490.13 EIM82819.1 - 5.2e-33 114.1 35.4 6.1e-33 113.8 24.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BTB PF00651.26 EIM82820.1 - 1.2e-12 47.7 0.0 2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.20 EIM82821.1 - 3.2e-63 213.7 0.3 3.7e-63 213.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 EIM82822.1 - 4.5e-77 257.2 0.0 5.1e-77 257.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIM82822.1 - 3.6e-13 49.2 0.0 3.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EIM82822.1 - 6.7e-12 44.9 0.0 8.4e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIM82822.1 - 2.6e-11 42.8 1.3 1.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIM82822.1 - 8.5e-10 38.1 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM82822.1 - 1.7e-07 31.7 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIM82822.1 - 0.00016 21.6 0.1 0.00043 20.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM82822.1 - 0.0064 15.9 0.0 0.029 13.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain L27 PF02828.11 EIM82822.1 - 0.0095 15.6 0.7 0.082 12.6 0.1 2.1 2 0 0 2 2 2 1 L27 domain 6PF2K PF01591.13 EIM82822.1 - 0.013 14.5 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LRR_8 PF13855.1 EIM82824.1 - 8.2e-16 57.5 14.5 3.8e-11 42.5 5.7 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIM82824.1 - 5e-15 54.7 16.1 1.7e-06 27.4 2.6 4.6 2 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM82824.1 - 4.3e-07 29.0 20.5 0.023 14.6 0.4 6.4 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 EIM82824.1 - 0.0039 17.1 16.2 0.53 10.6 0.2 5.2 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EIM82824.1 - 0.05 13.6 15.4 2.4 8.5 0.6 5.2 3 1 2 5 5 5 0 Leucine Rich repeat Caleosin PF05042.8 EIM82825.1 - 3.7e-10 39.6 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.1 EIM82825.1 - 0.059 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair UBA PF00627.26 EIM82826.1 - 8.9e-25 85.8 2.2 8.1e-13 47.7 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EIM82826.1 - 1.1e-20 72.7 1.3 1.8e-20 72.1 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EIM82826.1 - 6.6e-20 70.3 9.8 6.6e-20 70.3 6.8 2.0 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.3 EIM82826.1 - 3.5e-08 33.0 1.5 5.4e-08 32.4 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EIM82826.1 - 0.0019 17.7 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EIM82826.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 EIM82826.1 - 0.027 14.3 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LCAT PF02450.10 EIM82826.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2407 PF10302.4 EIM82826.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EIM82826.1 - 0.034 14.4 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2999 PF11212.3 EIM82826.1 - 0.17 11.9 0.8 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) MSA-2c PF12238.3 EIM82826.1 - 4.7 6.8 13.6 0.19 11.3 1.7 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c HALZ PF02183.13 EIM82827.1 - 0.0044 16.6 7.8 6.6 6.5 0.1 5.1 3 0 0 3 3 3 3 Homeobox associated leucine zipper GAS PF13851.1 EIM82827.1 - 0.11 11.7 69.8 0.012 14.7 2.9 5.6 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 EIM82827.1 - 0.82 9.0 55.5 0.57 9.6 5.1 5.8 2 2 4 6 6 6 0 Phage minor structural protein GP20 PPR_2 PF13041.1 EIM82828.1 - 1.1e-33 114.9 0.0 9.1e-08 31.9 0.0 7.7 6 2 2 8 8 8 6 PPR repeat family PPR_3 PF13812.1 EIM82828.1 - 1.7e-21 74.6 2.5 0.02 15.1 0.0 9.8 10 2 1 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 EIM82828.1 - 9.5e-16 56.6 2.0 0.0068 16.3 0.2 7.5 8 0 0 8 8 8 5 PPR repeat PPR_1 PF12854.2 EIM82828.1 - 4.7e-13 48.3 5.5 0.086 12.3 0.1 6.6 7 0 0 7 7 7 4 PPR repeat ECSIT PF06239.6 EIM82828.1 - 0.0012 17.7 0.1 3.9 6.2 0.0 4.0 3 2 2 5 5 5 2 Evolutionarily conserved signalling intermediate in Toll pathway Rad21_Rec8_N PF04825.8 EIM82829.1 - 3e-42 143.0 0.2 4.8e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EIM82829.1 - 1.5e-13 49.6 0.0 3.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EIM82829.1 - 0.0046 16.5 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein Adeno_E1A PF02703.9 EIM82829.1 - 0.046 13.1 0.2 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Early E1A protein CMD PF02627.15 EIM82830.1 - 4.5e-08 32.8 0.0 9.4e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family GSK-3_bind PF05350.7 EIM82831.1 - 0.0058 16.1 2.7 0.0058 16.1 1.9 1.5 2 0 0 2 2 2 1 Glycogen synthase kinase-3 binding Peptidase_C13 PF01650.13 EIM82831.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family PTPLA PF04387.9 EIM82832.1 - 3.8e-45 153.2 6.1 1.2e-38 132.0 1.2 2.6 3 0 0 3 3 3 2 Protein tyrosine phosphatase-like protein, PTPLA bZIP_1 PF00170.16 EIM82833.1 - 2.3e-05 24.2 15.0 4e-05 23.4 7.0 2.8 2 1 1 3 3 3 1 bZIP transcription factor FlgN PF05130.7 EIM82833.1 - 0.29 11.3 5.2 0.43 10.8 3.6 1.2 1 0 0 1 1 1 0 FlgN protein NIF PF03031.13 EIM82834.1 - 2.5e-52 176.7 0.3 3.4e-52 176.2 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_16 PF00722.16 EIM82836.1 - 9.5e-08 31.5 0.0 2.4e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 IncA PF04156.9 EIM82837.1 - 0.96 9.0 9.9 2.1 7.8 6.8 1.6 1 0 0 1 1 1 0 IncA protein PhzC-PhzF PF02567.11 EIM82838.1 - 2e-48 165.0 1.2 2.7e-48 164.5 0.8 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TPR_11 PF13414.1 EIM82839.1 - 7.9e-32 108.7 23.5 1.3e-06 27.9 0.0 10.9 9 3 2 11 11 11 10 TPR repeat TPR_2 PF07719.12 EIM82839.1 - 4e-30 101.2 25.8 0.00024 20.7 0.2 14.3 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_1 PF00515.23 EIM82839.1 - 3.9e-29 99.0 17.0 6.1e-06 25.6 0.1 12.8 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIM82839.1 - 2.2e-24 85.5 18.2 0.00019 21.6 0.0 9.6 9 2 1 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIM82839.1 - 5.7e-24 83.8 26.9 0.00025 20.9 0.1 9.9 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIM82839.1 - 8.1e-23 80.5 32.4 4.7e-06 27.1 0.8 10.7 10 2 1 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EIM82839.1 - 6.2e-22 76.1 23.6 0.02 15.4 0.0 13.3 11 3 4 15 15 12 7 Tetratricopeptide repeat TPR_8 PF13181.1 EIM82839.1 - 3.7e-14 51.3 9.0 0.02 14.6 0.1 10.5 12 0 0 12 12 12 3 Tetratricopeptide repeat Apc3 PF12895.2 EIM82839.1 - 1.3e-13 50.8 13.4 0.00082 19.4 0.3 6.5 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIM82839.1 - 2.4e-10 40.1 24.5 0.14 12.6 0.0 10.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM82839.1 - 5.5e-10 38.2 14.4 0.0053 16.4 0.2 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIM82839.1 - 5e-08 32.5 21.5 3.1 8.2 0.0 11.8 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM82839.1 - 4.6e-05 23.2 26.1 0.32 10.9 0.0 10.0 9 1 1 10 10 9 2 Tetratricopeptide repeat SWIRM PF04433.12 EIM82840.1 - 6.8e-16 58.1 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EIM82840.1 - 1.4e-09 37.8 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM82840.1 - 0.00074 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3795 PF12675.2 EIM82840.1 - 0.16 12.2 2.7 0.35 11.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) ZZ PF00569.12 EIM82840.1 - 0.19 11.3 5.0 0.42 10.1 3.5 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type PALP PF00291.20 EIM82841.1 - 2.4e-52 178.0 0.0 3.2e-51 174.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme p450 PF00067.17 EIM82842.1 - 2.8e-70 237.1 0.0 3.2e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UL11 PF11094.3 EIM82843.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein CoA_binding_2 PF13380.1 EIM82844.1 - 1.1e-30 106.1 0.0 1.3e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EIM82844.1 - 0.0086 16.5 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_18 PF00704.23 EIM82845.1 - 7.1e-60 203.2 2.8 8.2e-60 203.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.1 EIM82845.1 - 0.11 12.6 1.0 0.36 11.0 0.1 2.3 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase family 15 NUDIX PF00293.23 EIM82846.1 - 1.5e-15 56.9 0.1 2.7e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EIM82846.1 - 6.6e-13 48.8 0.0 1.6e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EIM82846.1 - 0.0013 18.1 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HMG_box PF00505.14 EIM82847.1 - 0.0052 17.0 0.7 0.008 16.4 0.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box ATP12 PF07542.6 EIM82847.1 - 0.057 13.3 0.7 0.083 12.8 0.2 1.5 2 0 0 2 2 2 0 ATP12 chaperone protein DUF2360 PF10152.4 EIM82847.1 - 0.31 11.3 3.2 0.34 11.1 2.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_carr PF00153.22 EIM82848.1 - 9.1e-65 214.4 4.7 4.4e-23 80.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF663 PF04950.7 EIM82849.1 - 2.2e-100 335.4 0.0 4.3e-100 334.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIM82849.1 - 6.6e-22 76.8 0.0 1.4e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CENP-B_dimeris PF09026.5 EIM82850.1 - 0.74 10.0 4.7 2.3 8.4 3.5 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DASH_Spc34 PF08657.5 EIM82851.1 - 8e-11 42.0 4.4 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 DASH complex subunit Spc34 DUF4407 PF14362.1 EIM82851.1 - 0.015 14.2 0.6 0.026 13.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_1 PF00175.16 EIM82852.1 - 1e-07 32.5 0.1 4.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIM82852.1 - 1.1e-07 31.8 0.0 4.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIM82852.1 - 0.007 16.2 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Med27 PF11571.3 EIM82853.1 - 1.8e-09 37.5 0.1 5e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 Mediator complex subunit 27 Phage_XkdX PF09693.5 EIM82854.1 - 0.046 13.2 0.2 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Ded_cyto PF06920.8 EIM82855.1 - 5.6e-42 143.0 0.0 1.1e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EIM82855.1 - 3.3e-33 114.8 0.0 7.5e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Asp PF00026.18 EIM82856.1 - 1.9e-65 221.2 12.1 2.3e-65 220.9 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM82856.1 - 2.6e-06 27.4 3.6 4.1e-06 26.8 1.5 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM82856.1 - 0.012 16.0 6.2 0.056 13.9 1.2 3.7 3 1 0 3 3 3 0 Aspartyl protease DFP PF04127.10 EIM82860.1 - 0.053 13.1 0.2 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SSB PF00436.20 EIM82860.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Single-strand binding protein family F-box PF00646.28 EIM82862.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.28 EIM82864.1 - 0.18 11.5 0.6 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 F-box domain zf-HIT PF04438.11 EIM82866.1 - 7.9e-09 35.0 14.8 1.1e-08 34.5 10.3 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EIM82866.1 - 0.033 14.0 12.1 0.052 13.4 8.4 1.3 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 EIM82866.1 - 0.23 11.3 6.8 0.34 10.8 4.7 1.2 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.1 EIM82866.1 - 0.36 11.2 6.9 0.55 10.6 4.8 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Kelch_4 PF13418.1 EIM82867.1 - 6.4e-21 73.8 8.6 1.4e-11 43.9 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EIM82867.1 - 1.1e-13 50.6 1.5 8.2e-06 25.7 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EIM82867.1 - 2.3e-12 46.6 23.7 1.6e-05 24.9 0.0 8.1 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EIM82867.1 - 2.8e-11 42.7 0.0 7.3e-08 31.8 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 EIM82867.1 - 2.4e-10 40.1 9.8 0.00024 20.9 0.1 5.7 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EIM82867.1 - 1.4e-09 37.3 2.2 0.0057 16.3 0.0 5.2 4 1 0 4 4 4 2 Kelch motif RAG2 PF03089.9 EIM82867.1 - 0.14 10.8 0.0 1.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Recombination activating protein 2 COesterase PF00135.23 EIM82868.1 - 6.8e-77 259.3 0.0 1.1e-76 258.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF2421 PF10334.4 EIM82868.1 - 3.1e-09 36.7 0.3 7.8e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIM82868.1 - 4.7e-06 25.5 2.0 0.0012 17.6 0.0 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 EIM82868.1 - 0.00036 19.1 3.3 0.0071 14.8 0.1 2.7 3 0 0 3 3 3 2 Fusaric acid resistance protein family DUF2422 PF10337.4 EIM82868.1 - 0.00049 19.0 0.1 0.00091 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) Abhydrolase_3 PF07859.8 EIM82868.1 - 0.00077 19.0 0.1 0.0022 17.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM82868.1 - 0.014 14.6 0.1 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF843 PF05814.6 EIM82868.1 - 0.42 10.4 1.3 1.1 9.1 0.9 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) GrpE PF01025.14 EIM82868.1 - 0.42 10.1 0.0 22 4.5 0.0 3.0 3 0 0 3 3 3 0 GrpE E1-E2_ATPase PF00122.15 EIM82868.1 - 2 7.4 6.2 3.8 6.4 4.3 1.3 1 0 0 1 1 1 0 E1-E2 ATPase Fungal_trans PF04082.13 EIM82869.1 - 2.6e-11 42.8 0.1 4.5e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM82869.1 - 8.9e-08 31.9 13.1 1.8e-07 30.9 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.16 EIM82870.1 - 7.6e-27 93.5 1.9 7.6e-27 93.5 1.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF3267 PF11667.3 EIM82870.1 - 0.13 12.5 6.1 3.7 7.7 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3267) Bax1-I PF01027.15 EIM82870.1 - 0.15 11.6 3.2 0.19 11.2 0.3 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PAP2_3 PF14378.1 EIM82870.1 - 0.16 11.4 2.4 1.1 8.7 1.7 2.0 1 1 0 1 1 1 0 PAP2 superfamily API5 PF05918.6 EIM82873.1 - 1.8e-23 82.9 0.1 2.3e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 EIM82873.1 - 5.4e-06 26.5 0.2 2.8e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.15 EIM82873.1 - 0.0014 17.0 0.3 0.0023 16.3 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region DUF1963 PF09234.5 EIM82873.1 - 0.089 13.0 0.1 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Cytochrom_B561 PF03188.11 EIM82874.1 - 1.6e-05 24.7 9.0 2.7e-05 24.0 6.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 EIM82874.1 - 0.49 9.6 13.2 0.32 10.2 2.7 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF998) Nucleoplasmin PF03066.10 EIM82874.1 - 2.8 7.4 8.3 4.2 6.8 5.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin S-methyl_trans PF02574.11 EIM82875.1 - 2.8e-40 138.5 0.0 3.9e-22 78.9 0.0 3.1 2 1 1 3 3 3 3 Homocysteine S-methyltransferase Ribosomal_S2 PF00318.15 EIM82876.1 - 1e-45 155.5 0.1 1.1e-23 83.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Zn_clus PF00172.13 EIM82878.1 - 0.0085 15.9 3.7 0.015 15.2 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_q6 PF01058.17 EIM82880.1 - 1.7e-22 79.4 0.1 2.6e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box-like PF12937.2 EIM82882.1 - 7.3e-06 25.6 0.1 1.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM82882.1 - 0.044 13.5 3.0 0.12 12.0 2.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.2 EIM82882.1 - 0.06 12.9 0.6 0.87 9.2 0.2 3.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) dCMP_cyt_deam_1 PF00383.17 EIM82883.1 - 5e-18 64.6 0.0 1.2e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EIM82883.1 - 0.0044 16.6 0.1 0.0077 15.8 0.0 1.4 2 0 0 2 2 2 1 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EIM82883.1 - 0.0059 16.2 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.1 EIM82883.1 - 0.047 13.5 0.5 0.12 12.2 0.4 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase XOO_2897-deam PF14440.1 EIM82883.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase RhgB_N PF09284.5 EIM82884.1 - 2.8e-86 288.8 5.4 4.5e-86 288.2 3.7 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EIM82884.1 - 2.3e-50 170.4 0.3 5.9e-50 169.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EIM82884.1 - 3.4e-15 55.9 1.3 1.1e-14 54.3 0.9 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II HMG_box PF00505.14 EIM82886.1 - 1.4e-12 47.6 0.3 1.4e-12 47.6 0.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM82886.1 - 3.7e-07 30.4 0.2 9e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain bZIP_1 PF00170.16 EIM82887.1 - 9.7e-06 25.4 5.2 1.9e-05 24.5 3.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIM82887.1 - 0.0062 16.3 5.3 0.011 15.4 3.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EIM82887.1 - 0.022 13.7 1.1 0.031 13.2 0.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ERAP1_C PF11838.3 EIM82887.1 - 0.04 13.1 0.5 0.055 12.7 0.3 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain CENP-Q PF13094.1 EIM82887.1 - 0.054 13.5 3.0 0.08 12.9 2.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Nnf1 PF03980.9 EIM82887.1 - 0.13 12.3 1.1 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Nnf1 His_Phos_1 PF00300.17 EIM82888.1 - 7.1e-23 81.4 1.3 1.5e-22 80.3 0.9 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EIM82888.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) SBF PF01758.11 EIM82889.1 - 1.4e-43 148.4 19.8 1.4e-43 148.4 13.7 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family SLT PF01464.15 EIM82890.1 - 4.2e-13 48.8 0.1 8.6e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Pyridox_oxidase PF01243.15 EIM82891.1 - 2.2e-09 37.2 0.0 5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EIM82891.1 - 0.0093 16.2 0.0 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase IU_nuc_hydro PF01156.14 EIM82892.1 - 8.2e-53 179.6 0.0 1.1e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RNase_H2-Ydr279 PF09468.5 EIM82893.1 - 3e-49 167.8 0.0 3.6e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Saccharop_dh PF03435.13 EIM82894.1 - 5.7e-72 242.8 0.0 7.9e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 EIM82894.1 - 4.9e-18 65.2 0.0 6.2e-17 61.6 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EIM82894.1 - 2.4e-12 47.0 0.0 4.6e-10 39.6 0.0 3.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 EIM82894.1 - 3.5e-05 23.9 0.1 8.6e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIM82894.1 - 0.0019 18.4 0.1 0.0058 16.9 0.1 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIM82894.1 - 0.0089 16.0 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EIM82894.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIM82894.1 - 0.3 10.8 0.8 9.5 6.0 0.0 2.4 1 1 1 2 2 2 0 ThiF family ABC1 PF03109.11 EIM82895.1 - 2.3e-24 85.6 0.0 4.8e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Adeno_VII PF03228.9 EIM82895.1 - 0.0096 16.5 0.1 0.019 15.5 0.0 1.4 1 0 0 1 1 1 1 Adenoviral core protein VII APH PF01636.18 EIM82895.1 - 0.089 12.5 0.1 0.25 11.0 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.6 EIM82895.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YHYH PF14240.1 EIM82896.1 - 0.013 15.1 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 YHYH protein DUF4127 PF13552.1 EIM82896.1 - 0.038 12.3 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) DUF1974 PF09317.6 EIM82896.1 - 0.055 12.8 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF4646 PF15496.1 EIM82897.1 - 3.3e-21 75.5 0.0 5.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF2931 PF11153.3 EIM82897.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2931) DUF4646 PF15496.1 EIM82898.1 - 5.9e-21 74.7 0.0 8.9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF2964 PF11177.3 EIM82899.1 - 0.022 14.6 0.6 0.022 14.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Metallophos PF00149.23 EIM82900.1 - 0.0038 16.6 0.0 0.046 13.0 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3382 PF11862.3 EIM82900.1 - 0.062 13.2 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) zf-MYND PF01753.13 EIM82901.1 - 0.062 13.1 8.5 0.12 12.2 5.9 1.5 1 0 0 1 1 1 0 MYND finger GATase_6 PF13522.1 EIM82901.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Glyoxal_oxid_N PF07250.6 EIM82902.1 - 1.1e-34 119.5 0.0 3.1e-31 108.2 0.0 4.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM82902.1 - 3.2e-22 78.4 0.4 6.9e-22 77.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM82902.1 - 0.18 11.5 10.1 3 7.6 0.1 4.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Arrestin_N PF00339.24 EIM82903.1 - 1.1e-10 41.5 0.0 8.6e-10 38.6 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIM82903.1 - 1.5e-05 24.5 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.17 EIM82903.1 - 5.9e-05 23.1 6.4 0.0048 17.0 5.5 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pyridoxal_deC PF00282.14 EIM82904.1 - 3.1e-23 81.8 0.0 4.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIM82904.1 - 7.7e-08 31.4 0.0 1.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIM82904.1 - 0.00046 19.3 0.3 0.00072 18.6 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EIM82904.1 - 0.095 11.8 0.0 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIM82904.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyoxal_oxid_N PF07250.6 EIM82905.1 - 8.4e-35 119.9 0.0 3.7e-31 108.0 0.0 3.9 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM82905.1 - 2.5e-22 78.7 0.1 5.2e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM82905.1 - 0.61 9.9 14.8 1.6 8.5 0.1 5.6 5 0 0 5 5 5 0 Galactose oxidase, central domain GFO_IDH_MocA PF01408.17 EIM82906.1 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM82906.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EIM82907.1 - 1e-16 61.5 0.0 1.9e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM82907.1 - 0.025 14.9 0.1 0.053 13.9 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GCV_T_C PF08669.6 EIM82907.1 - 0.03 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Polysacc_lyase PF14099.1 EIM82908.1 - 0.00053 19.7 0.4 0.0093 15.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase DUF1080 PF06439.6 EIM82908.1 - 0.0018 18.2 0.1 0.0093 15.8 0.0 2.0 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Mnd1 PF03962.10 EIM82909.1 - 5.1e-47 159.9 2.2 5.6e-47 159.8 1.5 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 EIM82909.1 - 0.0059 16.1 0.7 0.0086 15.6 0.5 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TrmB PF01978.14 EIM82909.1 - 0.021 14.5 0.0 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4094 PF13334.1 EIM82909.1 - 0.038 14.3 0.6 0.076 13.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TPR_12 PF13424.1 EIM82909.1 - 0.041 13.8 0.1 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FlgM PF04316.8 EIM82909.1 - 0.045 13.7 1.2 3.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM FlaC_arch PF05377.6 EIM82909.1 - 0.19 11.6 4.6 7.4 6.5 0.5 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MerR-DNA-bind PF09278.6 EIM82909.1 - 0.33 11.3 1.4 0.83 10.0 1.0 1.7 1 0 0 1 1 1 0 MerR, DNA binding XhlA PF10779.4 EIM82909.1 - 3.5 7.6 8.1 0.31 10.9 2.1 1.8 2 1 0 2 2 2 0 Haemolysin XhlA Pkinase PF00069.20 EIM82910.1 - 4.8e-44 150.4 0.0 6.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM82910.1 - 8.3e-16 57.8 0.0 6.6e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM82910.1 - 3.2e-05 23.0 0.0 4.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM82910.1 - 8.9e-05 21.9 0.1 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM82910.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM82910.1 - 0.00053 19.1 0.0 0.00084 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIM82910.1 - 0.095 12.2 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tim17 PF02466.14 EIM82912.1 - 1.6e-30 105.7 7.1 2e-30 105.4 4.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.4 EIM82913.1 - 1.8e-12 47.3 15.4 2e-11 43.9 10.7 2.3 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FadA PF09403.5 EIM82913.1 - 0.16 11.9 6.5 0.071 13.1 0.6 2.6 2 0 0 2 2 2 0 Adhesion protein FadA SWIM PF04434.12 EIM82914.1 - 2.1e-07 30.2 0.5 3.3e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 SWIM zinc finger Methyltransf_26 PF13659.1 EIM82915.1 - 4.5e-12 46.0 0.0 7.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIM82915.1 - 1e-11 44.7 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EIM82915.1 - 0.0055 16.2 0.0 1.1 8.6 0.0 2.6 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 EIM82915.1 - 0.046 12.7 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase MFS_1 PF07690.11 EIM82916.1 - 6.3e-14 51.4 37.2 6.3e-14 51.4 25.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EIM82917.1 - 1.1e-27 96.9 0.1 1.6e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM82917.1 - 2e-13 50.6 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM82917.1 - 8.5e-11 41.8 0.1 3.6e-10 39.7 0.1 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIM82917.1 - 1.9e-07 30.5 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM82917.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM82917.1 - 0.0061 16.0 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-U1 PF06220.7 EIM82918.1 - 7.8e-12 44.5 1.4 1.3e-11 43.8 0.9 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EIM82918.1 - 0.035 14.2 3.3 0.1 12.7 2.3 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF247 PF03140.10 EIM82918.1 - 0.12 11.3 0.9 0.17 10.8 0.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function zf-Dof PF02701.10 EIM82918.1 - 0.17 11.8 0.3 0.17 11.8 0.2 2.5 2 0 0 2 2 2 0 Dof domain, zinc finger His_Phos_2 PF00328.17 EIM82919.1 - 4.5e-07 29.5 0.0 1.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Muskelin_N PF06588.6 EIM82919.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Muskelin N-terminus Pam16 PF03656.8 EIM82920.1 - 1.2e-18 67.0 0.5 1.3e-10 41.1 0.2 2.4 2 1 0 2 2 2 2 Pam16 Sugarporin_N PF11471.3 EIM82920.1 - 0.35 10.5 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension SHS2_Rpb7-N PF03876.12 EIM82921.1 - 8.2e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Dioxygenase_C PF00775.16 EIM82922.1 - 1.9e-07 30.5 0.5 0.00037 19.7 0.1 2.3 2 0 0 2 2 2 2 Dioxygenase Fe_hyd_lg_C PF02906.9 EIM82923.1 - 2.1e-65 220.8 0.0 5.1e-65 219.5 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain His_Phos_2 PF00328.17 EIM82924.1 - 3.6e-08 33.1 0.0 9.9e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PI-PLC-X PF00388.14 EIM82925.1 - 7e-06 25.5 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AA_permease_2 PF13520.1 EIM82927.1 - 1.6e-43 148.8 44.6 2.3e-43 148.3 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM82927.1 - 4.3e-17 61.6 44.2 2.8e-16 58.9 30.6 2.2 1 1 0 1 1 1 1 Amino acid permease NADH_B2 PF14813.1 EIM82929.1 - 0.002 17.7 0.2 0.0023 17.5 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.6 EIM82929.1 - 0.072 13.3 0.0 0.072 13.3 0.0 1.0 1 0 0 1 1 1 0 SNARE associated Golgi protein Ferrochelatase PF00762.14 EIM82930.1 - 3.3e-94 315.3 0.0 3.8e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase NUDE_C PF04880.8 EIM82931.1 - 0.82 10.0 6.1 1.4 9.2 4.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3844 PF12955.2 EIM82932.1 - 7.1e-31 106.3 3.9 1.1e-30 105.8 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EIM82932.1 - 0.85 9.8 10.0 1.8 8.8 6.9 1.6 1 1 0 1 1 1 0 EGF-like domain DUF4407 PF14362.1 EIM82933.1 - 0.067 12.1 6.8 0.078 11.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIRS_C PF02769.17 EIM82933.1 - 0.079 12.9 0.3 0.12 12.3 0.2 1.3 1 1 0 1 1 1 0 AIR synthase related protein, C-terminal domain ATP-synt_B PF00430.13 EIM82933.1 - 0.11 12.2 15.3 0.15 11.8 10.6 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CAF-1_p150 PF11600.3 EIM82933.1 - 0.73 9.1 10.6 0.93 8.8 7.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Prefoldin_2 PF01920.15 EIM82934.1 - 1.5e-21 76.1 5.2 1.9e-21 75.8 3.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EIM82934.1 - 0.033 13.8 3.5 0.067 12.8 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit Sed5p PF11416.3 EIM82934.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein Sed5p YkyA PF10368.4 EIM82934.1 - 0.15 11.3 5.9 0.034 13.5 1.2 1.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein HrpB7 PF09486.5 EIM82934.1 - 0.75 9.6 4.8 4.2 7.2 1.8 2.2 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Phage_Gp23 PF10669.4 EIM82934.1 - 1.2 9.2 4.7 3.5 7.7 1.5 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3552 PF12072.3 EIM82934.1 - 1.5 7.9 7.5 4.9 6.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DivIC PF04977.10 EIM82934.1 - 2.4 7.7 6.4 2.2 7.8 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EIM82934.1 - 2.7 8.3 8.0 7 7.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Med9 PF07544.8 EIM82934.1 - 4.2 7.1 7.1 22 4.8 0.0 3.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-MYND PF01753.13 EIM82935.1 - 1.7e-09 37.4 14.6 3.2e-09 36.4 10.1 1.5 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.13 EIM82936.1 - 3.7e-08 32.5 0.0 1.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM82936.1 - 7.8e-08 32.1 12.0 1.3e-07 31.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4218 PF13960.1 EIM82938.1 - 9.8e-09 34.7 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIM82939.1 - 7.7e-06 25.1 0.0 4.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 UPF0181 PF03701.9 EIM82939.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Herpes_UL36 PF03586.8 EIM82943.1 - 0.035 13.1 0.1 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein BTB PF00651.26 EIM82944.1 - 0.02 14.8 0.0 0.053 13.5 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3049 PF11250.3 EIM82944.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) W2 PF02020.13 EIM82945.1 - 2.1e-20 72.4 3.8 2.5e-20 72.2 0.2 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3606 PF12244.3 EIM82946.1 - 0.035 13.7 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Cyclin PF08613.6 EIM82947.1 - 3.7e-09 37.1 0.0 2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 EIM82947.1 - 0.038 13.5 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain RRM_1 PF00076.17 EIM82949.1 - 1.9e-26 91.4 0.0 2.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM82949.1 - 3.6e-20 71.7 0.0 4.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM82949.1 - 2.8e-13 49.5 0.0 3.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 EIM82949.1 - 0.081 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) ABC_tran PF00005.22 EIM82950.1 - 1.8e-35 122.2 0.0 3e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIM82950.1 - 2e-28 99.6 6.7 3.5e-28 98.8 4.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EIM82950.1 - 2.8e-07 30.8 0.0 4.6e-05 23.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM82950.1 - 8.8e-06 25.8 0.1 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EIM82950.1 - 7.7e-05 22.0 0.3 0.0014 17.8 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIM82950.1 - 0.0016 17.9 0.2 0.0038 16.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIM82950.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM82950.1 - 0.004 17.2 0.1 0.021 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM82950.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EIM82950.1 - 0.1 12.5 0.2 0.86 9.5 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 EIM82950.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MBD_C PF14048.1 EIM82951.1 - 0.024 15.2 0.6 0.032 14.8 0.4 1.3 1 1 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 NmrA PF05368.8 EIM82952.1 - 4.5e-25 88.2 0.0 1.3e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM82952.1 - 8.2e-12 45.5 0.1 2.3e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM82952.1 - 0.038 13.6 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 KR domain Glyco_hydro_71 PF03659.9 EIM82953.1 - 1.9e-50 171.4 5.9 2.4e-50 171.1 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Alpha_GJ PF03229.8 EIM82954.1 - 0.14 12.4 0.2 0.14 12.4 0.1 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Vps53_N PF04100.7 EIM82955.1 - 6.3e-79 265.5 0.0 9.7e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 EIM82955.1 - 0.0037 15.4 1.6 0.004 15.3 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF2450 PF10475.4 EIM82955.1 - 0.0041 16.0 4.9 0.0086 15.0 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EIM82955.1 - 0.023 14.4 2.5 0.062 13.0 1.7 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 His_Phos_2 PF00328.17 EIM82957.1 - 4.6e-42 144.5 0.0 5.5e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GCS PF03074.11 EIM82958.1 - 3.3e-159 529.8 0.0 3.6e-129 431.0 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase S1 PF00575.18 EIM82958.1 - 0.014 15.4 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 S1 RNA binding domain GCS2 PF04107.8 EIM82958.1 - 0.028 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) His_Phos_2 PF00328.17 EIM82959.1 - 1e-33 117.1 0.0 1.3e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1253 PF06862.7 EIM82960.1 - 2.9e-146 487.3 0.0 3.7e-146 487.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EIM82960.1 - 0.0085 15.6 0.1 0.027 13.9 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase YHYH PF14240.1 EIM82960.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 YHYH protein Topoisom_bac PF01131.15 EIM82961.1 - 1.5e-93 313.8 0.0 1.8e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EIM82961.1 - 3.4e-22 78.3 0.0 2.4e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.18 EIM82962.1 - 1.3e-18 65.8 26.7 8.6e-07 28.6 3.1 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-GRF PF06839.7 EIM82962.1 - 4.7e-13 48.8 4.4 4.9e-12 45.5 1.6 3.2 2 0 0 2 2 2 1 GRF zinc finger zf-CCHC_3 PF13917.1 EIM82962.1 - 1.7e-10 40.4 9.3 0.006 16.2 0.3 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 EIM82962.1 - 0.00091 18.8 14.7 0.53 10.0 0.5 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 EIM82962.1 - 0.049 13.1 13.1 1.2 8.7 0.3 3.3 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.3 EIM82962.1 - 0.091 12.6 9.1 5.4 6.9 0.4 3.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G MFS_1 PF07690.11 EIM82963.1 - 1.5e-29 102.8 37.9 2.2e-29 102.2 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4079 PF13301.1 EIM82963.1 - 0.41 10.6 6.1 5 7.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Mannosyl_trans2 PF04188.8 EIM82964.1 - 5.6e-60 203.4 16.4 7.8e-60 203.0 11.4 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pex24p PF06398.6 EIM82965.1 - 2e-25 89.3 24.5 2.7e-24 85.6 17.0 2.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCHC PF00098.18 EIM82966.1 - 2e-10 40.0 5.7 0.00011 21.9 0.4 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIM82966.1 - 0.00015 21.3 4.7 0.069 12.8 0.2 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIM82966.1 - 0.007 16.0 0.6 0.52 10.0 0.1 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-BED PF02892.10 EIM82966.1 - 0.017 14.8 1.2 0.55 10.0 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-CCHC_6 PF15288.1 EIM82966.1 - 0.033 13.8 10.1 0.8 9.4 1.6 2.9 3 0 0 3 3 3 0 Zinc knuckle Rpr2 PF04032.11 EIM82966.1 - 0.1 12.5 2.2 7.4 6.5 0.1 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC_2 PF13696.1 EIM82966.1 - 0.26 10.8 5.4 15 5.1 2.1 2.9 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM82966.1 - 1.7 8.1 8.4 3.6 7.1 1.6 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Asparaginase_2 PF01112.13 EIM82968.1 - 2.2e-55 187.6 0.0 4e-40 137.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.16 EIM82968.1 - 0.02 13.4 0.3 0.043 12.3 0.2 1.5 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Epimerase PF01370.16 EIM82969.1 - 3.6e-20 72.4 0.0 5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM82969.1 - 1.2e-07 30.7 0.0 1.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM82969.1 - 4e-07 30.2 0.3 1.7e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM82969.1 - 1e-05 24.6 0.2 0.00019 20.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM82969.1 - 9.2e-05 21.8 0.1 0.00017 20.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Dynamitin PF04912.9 EIM82970.1 - 3.4e-25 88.6 8.5 9.3e-25 87.2 5.9 1.7 1 1 0 1 1 1 1 Dynamitin Laminin_II PF06009.7 EIM82970.1 - 0.012 15.4 6.0 0.061 13.0 0.3 3.0 3 0 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EIM82970.1 - 0.021 14.6 5.5 0.56 10.0 0.2 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 EIM82970.1 - 0.022 13.5 2.5 0.32 9.6 0.0 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nnf1 PF03980.9 EIM82970.1 - 0.023 14.6 1.6 0.67 9.9 0.4 3.1 2 1 1 3 3 3 0 Nnf1 EzrA PF06160.7 EIM82970.1 - 0.045 11.9 0.1 0.045 11.9 0.1 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA RmuC PF02646.11 EIM82970.1 - 0.065 12.0 1.4 0.45 9.2 0.0 2.5 3 0 0 3 3 3 0 RmuC family DUF4164 PF13747.1 EIM82970.1 - 0.2 11.8 6.7 0.43 10.7 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 EIM82970.1 - 0.25 11.5 6.0 13 5.9 0.2 3.5 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EIM82970.1 - 0.36 10.8 7.1 7 6.7 0.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 EIM82970.1 - 0.38 10.5 5.9 0.087 12.5 0.3 2.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Matrilin_ccoil PF10393.4 EIM82970.1 - 0.42 10.0 5.5 32 3.9 0.0 4.4 4 1 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2408 PF10303.4 EIM82970.1 - 0.78 9.8 6.0 2.7 8.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.7 EIM82970.1 - 0.83 9.4 8.7 0.062 13.0 0.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 EIM82970.1 - 1 9.2 5.9 9.5 6.0 0.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 EIM82970.1 - 1.3 9.4 4.5 5 7.5 0.0 3.6 2 1 2 4 4 4 0 Syntaxin 6, N-terminal FlgN PF05130.7 EIM82970.1 - 4.7 7.4 7.8 0.26 11.5 0.4 2.5 2 2 0 3 3 3 0 FlgN protein IncA PF04156.9 EIM82970.1 - 7.7 6.0 14.4 1.2 8.6 0.4 2.8 3 1 0 3 3 3 0 IncA protein NPV_P10 PF05531.7 EIM82970.1 - 8.7 6.6 7.7 5.1 7.4 0.1 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Con-6 PF10346.4 EIM82972.1 - 5.2e-41 137.7 11.0 7.3e-14 50.9 1.6 3.1 3 0 0 3 3 3 3 Conidiation protein 6 ALS2CR8 PF15299.1 EIM82972.1 - 0.045 13.3 1.0 0.11 12.0 0.1 1.9 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SpoIIIAH PF12685.2 EIM82972.1 - 0.055 12.9 0.2 0.83 9.1 0.0 2.4 2 1 0 2 2 2 0 SpoIIIAH-like protein HbrB PF08539.6 EIM82973.1 - 7.2e-36 123.4 0.0 1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Peptidase_M22 PF00814.20 EIM82974.1 - 1.7e-68 231.0 0.0 2.1e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EIM82974.1 - 0.12 12.0 0.1 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein DUF572 PF04502.8 EIM82975.1 - 6.1e-88 295.1 4.0 8e-88 294.7 2.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 EIM82975.1 - 0.0052 17.2 0.4 0.017 15.5 0.1 1.9 2 0 0 2 2 2 1 HrpA pilus formation protein zf-FCS PF06467.9 EIM82975.1 - 0.019 14.6 0.9 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 EIM82975.1 - 0.047 13.1 0.1 0.088 12.2 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Lar_restr_allev PF14354.1 EIM82975.1 - 0.17 12.2 0.6 7.1 7.0 1.0 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Mis14 PF08641.7 EIM82976.1 - 0.0067 16.4 1.9 0.0067 16.4 1.3 1.7 1 1 1 2 2 2 1 Kinetochore protein Mis14 like PMC2NT PF08066.7 EIM82976.1 - 0.049 13.9 1.1 1.2 9.4 0.1 2.4 2 1 1 3 3 3 0 PMC2NT (NUC016) domain BAG PF02179.11 EIM82977.1 - 0.0023 17.9 0.2 0.0053 16.8 0.1 1.6 1 0 0 1 1 1 1 BAG domain FUSC-like PF12805.2 EIM82977.1 - 0.35 9.7 1.3 0.79 8.5 0.0 1.9 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS XPG_I PF00867.13 EIM82978.1 - 1.8e-17 63.1 0.0 3.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIM82978.1 - 5.6e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain SNF2_N PF00176.18 EIM82979.1 - 2.3e-40 138.2 0.0 4.9e-40 137.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM82979.1 - 2e-11 43.5 0.0 3.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Amidohydro_3 PF07969.6 EIM82980.1 - 1.2e-75 255.2 0.1 1.5e-75 254.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIM82980.1 - 6.1e-06 26.4 0.6 0.069 13.1 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIM82980.1 - 7.6e-05 22.5 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM82980.1 - 0.0024 17.6 0.0 0.0072 16.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase zf-rbx1 PF12678.2 EIM82981.1 - 9.4e-14 51.2 0.8 1.7e-13 50.4 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIM82981.1 - 1.4e-11 44.0 7.0 6.2e-11 41.9 4.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM82981.1 - 7.4e-08 31.9 2.0 1.5e-07 30.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM82981.1 - 2.4e-06 27.0 5.4 5.3e-05 22.8 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM82981.1 - 3.7e-06 26.8 2.6 3.7e-06 26.8 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM82981.1 - 1e-05 25.2 0.5 1.9e-05 24.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIM82981.1 - 1.8e-05 24.3 3.8 6.6e-05 22.5 2.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIM82981.1 - 0.00079 19.0 5.1 0.002 17.7 3.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIM82981.1 - 0.0024 17.7 2.1 0.0053 16.6 1.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EIM82981.1 - 0.027 14.4 0.3 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EIM82981.1 - 1.7 8.2 3.8 0.9 9.1 0.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.5 EIM82982.1 - 1.6e-24 86.3 1.5 1.9e-24 86.1 1.0 1.0 1 0 0 1 1 1 1 Yqey-like protein SSP160 PF06933.6 EIM82982.1 - 0.099 10.6 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2419 PF10343.4 EIM82983.1 - 3.7e-08 32.9 0.0 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) Phage_P2_GpU PF06995.6 EIM82983.1 - 0.0062 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Phage P2 GpU NAD_kinase PF01513.16 EIM82984.1 - 9.5e-67 224.7 0.0 3.6e-66 222.8 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase DUF2638 PF10937.3 EIM82984.1 - 0.07 14.1 2.4 0.11 13.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Spt5_N PF11942.3 EIM82984.1 - 0.084 13.4 17.4 2.4 8.8 10.8 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3435 PF11917.3 EIM82984.1 - 0.085 11.5 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) NOA36 PF06524.7 EIM82984.1 - 0.45 9.7 6.7 0.79 8.9 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EIM82984.1 - 1.8 6.9 19.1 3.9 5.8 13.2 1.5 1 0 0 1 1 1 0 Daxx Family HSP9_HSP12 PF04119.7 EIM82986.1 - 6.7e-22 77.3 6.7 6.7e-22 77.3 4.6 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 Gti1_Pac2 PF09729.4 EIM82987.1 - 5.2e-32 111.0 9.6 1.3e-25 90.2 0.0 3.9 3 2 0 3 3 3 2 Gti1/Pac2 family Josephin PF02099.12 EIM82988.1 - 3.6e-48 163.1 0.0 7.9e-48 162.0 0.0 1.5 1 0 0 1 1 1 1 Josephin ATG27 PF09451.5 EIM82989.1 - 1.2e-43 149.3 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EIM82989.1 - 0.00019 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cauli_VI PF01693.11 EIM82990.1 - 5.7e-13 48.6 0.1 9.3e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin HSP9_HSP12 PF04119.7 EIM82991.1 - 7.4e-20 70.7 7.8 7.4e-20 70.7 5.4 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 DASH_Duo1 PF08651.5 EIM82992.1 - 2.1e-13 49.6 0.1 3.3e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF572 PF04502.8 EIM82992.1 - 0.12 11.5 15.8 0.2 10.8 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3611 PF12263.3 EIM82993.1 - 1.6 8.0 10.9 0.021 14.2 1.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) TGT PF01702.13 EIM82994.1 - 6.1e-80 267.9 0.0 7.8e-80 267.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.20 EIM82995.1 - 7.6e-77 258.3 0.0 9.4e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EIM82995.1 - 0.00018 20.8 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain Peptidase_S10 PF00450.17 EIM82996.1 - 9.4e-85 285.2 0.1 1.2e-84 284.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase EMP70 PF02990.11 EIM82997.1 - 5e-186 619.2 0.0 6.3e-186 618.8 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_S9 PF00380.14 EIM82998.1 - 6.7e-32 110.2 0.9 9.5e-31 106.5 0.6 2.3 1 1 0 1 1 1 1 Ribosomal protein S9/S16 Pterin_4a PF01329.14 EIM82999.1 - 8.4e-05 22.2 0.5 0.00016 21.3 0.4 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase CoxIIa PF08113.6 EIM82999.1 - 1.1 8.9 5.3 2.3 8.0 3.6 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family GHMP_kinases_N PF00288.21 EIM83000.1 - 1.1e-09 38.2 3.4 2.4e-09 37.1 2.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Exo_endo_phos PF03372.18 EIM83001.1 - 1.6e-21 77.3 0.1 2.2e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EIM83001.1 - 5.4e-17 61.0 5.4 1.2e-08 34.4 2.7 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM83001.1 - 2.5e-12 46.3 21.3 2e-08 33.8 4.2 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EIM83001.1 - 9.2e-10 37.1 5.6 0.02 14.8 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIM83001.1 - 1.9e-06 27.1 4.8 0.17 12.2 0.0 4.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EIM83001.1 - 0.051 13.6 4.5 10 6.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Relaxase PF03432.9 EIM83001.1 - 0.16 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Muskelin_N PF06588.6 EIM83002.1 - 6.9e-34 117.2 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EIM83002.1 - 2.1e-28 97.7 4.0 1e-10 41.4 0.1 7.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EIM83002.1 - 1.6e-22 78.9 4.4 3.4e-07 29.9 0.0 6.7 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIM83002.1 - 1.1e-19 69.9 5.5 1.1e-07 31.6 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EIM83002.1 - 3.8e-19 67.9 2.6 7.1e-06 25.9 0.1 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EIM83002.1 - 1.2e-11 43.8 3.5 2.3e-05 23.9 0.6 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EIM83002.1 - 5.7e-11 41.7 10.1 2.3e-06 27.0 0.1 5.4 5 1 0 5 5 5 2 Kelch motif DUF3533 PF12051.3 EIM83003.1 - 7.8e-98 327.7 16.9 9.3e-98 327.4 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EIM83003.1 - 3.1e-12 46.2 26.8 4.1e-12 45.7 18.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.7 EIM83003.1 - 0.12 12.0 0.1 0.46 10.1 0.0 2.0 1 0 0 1 1 1 0 CDR ABC transporter bZIP_2 PF07716.10 EIM83004.1 - 4.7e-11 42.3 10.8 9.7e-11 41.3 7.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIM83004.1 - 1.3e-06 28.2 7.8 1.3e-06 28.2 5.4 1.9 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.4 EIM83004.1 - 0.0029 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Haemolysin XhlA MAD PF05557.8 EIM83004.1 - 0.0042 15.2 0.9 0.0058 14.7 0.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein bZIP_Maf PF03131.12 EIM83004.1 - 0.024 14.9 4.8 0.069 13.4 3.3 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor SR-25 PF10500.4 EIM83004.1 - 0.057 12.8 8.2 0.11 11.9 5.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CASP_C PF08172.7 EIM83004.1 - 0.057 12.4 1.0 0.083 11.9 0.7 1.2 1 0 0 1 1 1 0 CASP C terminal TSC22 PF01166.13 EIM83004.1 - 0.073 13.0 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family zf-CCCH PF00642.19 EIM83005.1 - 9.2e-09 34.7 2.5 1.9e-08 33.8 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EIM83005.1 - 1.4e-07 31.0 7.7 2.5e-07 30.3 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIM83005.1 - 1.7e-07 30.7 4.4 2.9e-07 30.0 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM83005.1 - 3.2e-07 30.2 9.4 5.9e-07 29.4 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM83005.1 - 1.8e-06 27.6 6.5 3e-06 26.9 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM83005.1 - 5.3e-06 25.9 8.2 1e-05 25.0 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM83005.1 - 0.0019 18.0 7.2 0.0042 16.9 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM83005.1 - 0.003 17.2 5.4 0.003 17.2 3.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Ribosomal_L34e PF01199.13 EIM83005.1 - 0.097 12.8 4.0 0.14 12.3 0.7 2.4 2 0 0 2 2 2 0 Ribosomal protein L34e zf-Nse PF11789.3 EIM83005.1 - 0.16 11.4 1.8 0.38 10.3 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EIM83005.1 - 0.17 11.7 3.3 0.32 10.8 2.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EIM83005.1 - 0.99 9.5 4.0 3.1 7.9 2.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C2H2_4 PF13894.1 EIM83006.1 - 2.3e-10 40.0 6.7 0.00015 21.8 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM83006.1 - 8.3e-10 38.4 10.7 0.00014 21.9 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIM83006.1 - 1.8e-06 27.6 5.8 0.0055 16.5 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIM83006.1 - 8.6e-05 22.6 2.7 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM83006.1 - 0.0007 19.6 2.3 0.099 12.8 0.2 2.5 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EIM83006.1 - 0.0029 17.8 2.2 0.0029 17.8 1.6 3.8 3 1 0 3 3 3 2 Zinc-finger double domain zf-met2 PF12907.2 EIM83006.1 - 0.034 14.1 4.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding zf-C2HC_2 PF13913.1 EIM83006.1 - 0.072 12.7 1.9 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EIM83006.1 - 0.087 12.9 4.2 0.28 11.3 0.7 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 EIM83006.1 - 0.19 11.6 3.5 0.38 10.6 2.4 1.5 1 1 0 1 1 1 0 FYVE zinc finger GAGA PF09237.6 EIM83006.1 - 0.19 11.3 4.2 3.1 7.4 0.6 2.3 1 1 1 2 2 2 0 GAGA factor zf-BED PF02892.10 EIM83006.1 - 3.1 7.6 14.1 0.7 9.6 1.9 2.7 3 0 0 3 3 3 0 BED zinc finger SpdB PF05122.8 EIM83006.1 - 5.9 7.0 7.0 17 5.5 0.1 2.8 3 0 0 3 3 3 0 Mobile element transfer protein Metallophos PF00149.23 EIM83007.1 - 3.2e-40 137.6 0.3 4.1e-40 137.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM83007.1 - 0.0051 16.6 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CRAL_TRIO PF00650.15 EIM83008.1 - 4.5e-11 42.4 0.0 7.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain COesterase PF00135.23 EIM83009.1 - 1.2e-57 195.8 0.0 1.8e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM83009.1 - 9.2e-07 28.6 0.2 2.2e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_49 PF13896.1 EIM83010.1 - 2.8e-35 121.9 0.2 1.8e-28 99.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan GTP_EFTU PF00009.22 EIM83013.1 - 1.2e-22 80.3 0.0 2.7e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIM83013.1 - 6.3e-16 58.3 0.0 1.8e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIM83013.1 - 2.6e-10 40.2 2.7 7.1e-10 38.8 0.7 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIM83013.1 - 0.0097 15.5 3.6 0.011 15.3 0.8 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIM83013.1 - 0.02 14.8 1.1 0.059 13.3 0.3 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM83013.1 - 0.061 12.6 0.1 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Gti1_Pac2 PF09729.4 EIM83014.1 - 1.1e-18 67.6 0.0 3e-16 59.7 0.0 2.5 2 1 0 2 2 2 2 Gti1/Pac2 family GLTP PF08718.6 EIM83015.1 - 6.2e-40 136.6 0.0 1.5e-39 135.4 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) GAF PF01590.21 EIM83016.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.3 1 1 0 1 1 1 0 GAF domain tRNA-synt_1e PF01406.14 EIM83017.1 - 1.6e-127 424.7 0.0 3e-127 423.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EIM83017.1 - 2e-09 36.6 1.5 1.5e-05 23.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIM83017.1 - 8.7e-07 27.3 0.0 0.00021 19.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EIM83017.1 - 0.05 12.2 0.1 3.2 6.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) Gti1_Pac2 PF09729.4 EIM83018.1 - 1e-23 84.0 0.0 3.2e-19 69.4 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 EIM83019.1 - 2.7e-15 56.6 3.3 1.9e-14 53.9 0.0 3.0 3 1 1 4 4 4 1 Gti1/Pac2 family TFIIA PF03153.8 EIM83020.1 - 1.4e-49 170.0 0.5 7.4e-30 105.0 0.1 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3533 PF12051.3 EIM83021.1 - 3.7e-100 335.3 18.7 4.4e-100 335.0 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) zf-RING_2 PF13639.1 EIM83022.1 - 6.4e-12 45.1 1.7 2e-09 37.1 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EIM83022.1 - 1.6e-07 31.3 1.7 8.2e-06 25.8 0.1 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM83022.1 - 2e-07 30.8 1.9 9.2e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM83022.1 - 1.4e-05 24.6 0.4 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM83022.1 - 3.9e-05 23.2 1.0 0.00011 21.8 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM83022.1 - 4.1e-05 23.2 0.7 9.9e-05 21.9 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIM83022.1 - 0.00036 20.3 0.7 0.0027 17.4 0.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EIM83022.1 - 0.0004 19.8 0.5 0.00091 18.7 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 EIM83022.1 - 0.0087 15.5 0.5 0.022 14.1 0.1 1.9 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EIM83022.1 - 0.022 14.4 0.7 0.022 14.4 0.5 2.4 2 1 1 3 3 3 0 RING-type zinc-finger Rtf2 PF04641.7 EIM83022.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DNA_ligase_ZBD PF03119.11 EIM83022.1 - 0.069 12.8 1.3 0.17 11.6 0.9 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain FANCL_C PF11793.3 EIM83022.1 - 0.079 12.9 4.7 0.55 10.2 1.7 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 EIM83022.1 - 0.14 12.2 0.7 0.28 11.2 0.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EIM83022.1 - 0.19 11.3 0.1 0.19 11.3 0.1 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIM83022.1 - 0.9 9.4 2.9 0.53 10.2 0.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EIM83022.1 - 2 8.5 4.0 0.98 9.5 0.7 1.9 2 0 0 2 2 2 0 RING-variant domain 5_nucleotid_C PF02872.13 EIM83023.1 - 4.2e-23 82.0 0.0 8.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIM83023.1 - 3.4e-08 33.1 0.1 6.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rubis-subs-bind PF09273.6 EIM83024.1 - 2.8e-13 49.8 0.5 5.3e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EIM83024.1 - 2.1e-11 44.3 0.0 6.2e-11 42.8 0.0 1.8 2 1 0 2 2 2 1 SET domain ATP-synt_C PF00137.16 EIM83025.1 - 2.3e-27 94.6 30.5 8.5e-17 60.8 5.2 2.8 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EIM83025.1 - 0.11 12.7 2.0 3.8 7.7 0.7 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF373 PF04123.8 EIM83025.1 - 0.87 8.5 10.3 0.23 10.4 4.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Cation_efflux PF01545.16 EIM83025.1 - 1.2 8.1 9.6 0.11 11.5 1.1 2.5 1 1 1 3 3 3 0 Cation efflux family Arf PF00025.16 EIM83026.1 - 2.3e-38 131.1 0.0 6.1e-38 129.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIM83026.1 - 4e-12 45.5 0.0 1e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EIM83026.1 - 6.3e-08 32.1 0.0 1e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIM83026.1 - 7.5e-08 31.8 0.0 8.4e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM83026.1 - 4e-07 30.5 0.0 6.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIM83026.1 - 4.1e-06 26.1 0.0 7.5e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIM83026.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM83026.1 - 0.0001 21.7 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EIM83026.1 - 0.0016 17.9 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EIM83026.1 - 0.0048 17.7 0.6 0.0088 16.8 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM83026.1 - 0.0066 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIM83026.1 - 0.0069 16.6 0.5 0.016 15.5 0.3 1.8 1 1 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 EIM83026.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 EIM83026.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM83026.1 - 0.036 13.7 0.2 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EIM83026.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIM83026.1 - 0.039 13.0 0.3 0.072 12.1 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 EIM83026.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EIM83026.1 - 0.058 13.3 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM83026.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EIM83026.1 - 0.078 13.2 1.3 0.11 12.8 0.9 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM83026.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EIM83026.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIM83026.1 - 0.16 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIM83026.1 - 0.29 11.4 1.4 0.55 10.5 1.0 1.8 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EIM83027.1 - 0.00078 19.6 3.2 0.13 12.6 1.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 EIM83027.1 - 0.018 15.1 1.8 0.037 14.1 1.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EIM83027.1 - 0.13 12.5 6.3 0.38 11.1 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 EIM83027.1 - 0.21 11.3 2.4 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 EIM83027.1 - 2.6 8.5 7.9 34 5.0 0.0 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type Rpr2 PF04032.11 EIM83030.1 - 2.7e-19 68.8 0.1 5.7e-19 67.7 0.1 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3795 PF12675.2 EIM83030.1 - 0.13 12.4 1.2 0.21 11.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) FAM53 PF15242.1 EIM83030.1 - 0.14 11.6 2.5 0.14 11.7 0.2 1.7 1 1 1 2 2 2 0 Family of FAM53 DUF3275 PF11679.3 EIM83030.1 - 0.4 10.2 3.0 1.9 8.0 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) RRF PF01765.14 EIM83031.1 - 1e-27 96.6 0.4 1.7e-27 95.9 0.3 1.3 1 0 0 1 1 1 1 Ribosome recycling factor WH2 PF02205.15 EIM83031.1 - 0.028 14.0 1.6 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 WH2 motif Oest_recep PF02159.10 EIM83031.1 - 0.67 10.0 7.0 0.13 12.4 2.2 1.8 2 0 0 2 2 2 0 Oestrogen receptor Yippee-Mis18 PF03226.9 EIM83032.1 - 2.1e-17 62.9 0.0 2.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 EIM83032.1 - 0.073 12.7 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIM83032.1 - 0.11 12.1 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC PF00098.18 EIM83033.1 - 1.1e-10 40.9 26.8 0.0026 17.5 0.2 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EIM83033.1 - 0.0016 17.9 15.5 0.02 14.3 0.1 4.2 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EIM83033.1 - 0.38 10.4 25.7 0.17 11.6 0.7 4.2 4 0 0 4 4 4 0 Zinc knuckle zf-TFIIIC PF12660.2 EIM83033.1 - 1.8 8.4 7.3 1.1 9.2 1.3 2.3 1 1 1 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex ABC_tran PF00005.22 EIM83035.1 - 3.8e-42 143.8 1.8 1.8e-20 73.6 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EIM83035.1 - 5e-19 69.3 0.0 1.2e-10 41.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EIM83035.1 - 8.6e-13 48.0 0.9 0.00017 20.9 0.1 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIM83035.1 - 9.8e-10 37.8 0.7 0.00044 19.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EIM83035.1 - 3.2e-06 27.3 0.1 0.092 12.9 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EIM83035.1 - 8.4e-06 25.0 0.3 0.046 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EIM83035.1 - 2.1e-05 24.2 0.1 0.18 11.4 0.0 2.7 2 1 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EIM83035.1 - 2.1e-05 24.5 0.2 0.0076 16.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM83035.1 - 2.5e-05 24.3 5.6 0.01 15.8 0.7 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EIM83035.1 - 2.6e-05 24.1 2.1 0.74 9.7 0.1 3.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EIM83035.1 - 2.6e-05 24.1 0.8 0.077 12.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIM83035.1 - 5.5e-05 23.9 1.4 0.022 15.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EIM83035.1 - 6.6e-05 22.3 0.1 0.28 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EIM83035.1 - 0.00011 22.0 1.0 0.37 10.5 0.0 2.9 2 1 0 2 2 2 2 Dynamin family RNA_helicase PF00910.17 EIM83035.1 - 0.0003 20.9 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.1 EIM83035.1 - 0.00047 20.3 0.1 0.6 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIM83035.1 - 0.00051 19.1 0.3 0.11 11.4 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain MobB PF03205.9 EIM83035.1 - 0.0007 19.3 0.7 0.82 9.3 0.1 2.8 2 1 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran_2 PF12848.2 EIM83035.1 - 0.00078 19.2 2.8 0.00078 19.2 1.9 3.0 3 1 0 3 3 2 1 ABC transporter ATP-synt_ab PF00006.20 EIM83035.1 - 0.0011 18.5 0.6 0.77 9.2 0.0 2.4 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 EIM83035.1 - 0.0016 18.9 0.1 0.17 12.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EIM83035.1 - 0.0024 18.1 1.7 0.39 11.0 0.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIM83035.1 - 0.0025 18.1 16.0 0.67 10.2 0.0 4.1 3 1 0 3 3 3 2 AAA domain NB-ARC PF00931.17 EIM83035.1 - 0.004 16.0 0.0 0.91 8.3 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.8 EIM83035.1 - 0.0067 15.3 0.2 0.73 8.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIM83035.1 - 0.012 15.2 0.3 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EIM83035.1 - 0.037 13.9 0.2 0.56 10.1 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIM83035.1 - 0.057 12.8 4.7 0.69 9.2 0.2 2.8 2 1 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EIM83035.1 - 0.058 12.8 0.1 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIN PF01850.16 EIM83035.1 - 0.092 13.0 4.2 1 9.6 1.8 2.5 2 0 0 2 2 2 0 PIN domain MmgE_PrpD PF03972.9 EIM83036.1 - 2.8e-160 533.3 0.0 3.1e-160 533.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family zf-SNAP50_C PF12251.3 EIM83038.1 - 2.8e-26 92.0 0.0 4.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Fez1 PF06818.10 EIM83039.1 - 1.2 9.0 24.3 0.11 12.5 10.2 2.7 2 1 0 2 2 2 0 Fez1 APG6 PF04111.7 EIM83039.1 - 4.2 6.3 28.0 0.019 14.0 12.5 2.1 2 1 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EIM83039.1 - 6.6 6.2 30.3 10 5.6 0.0 3.2 2 1 0 2 2 2 0 IncA protein Peptidase_S49_N PF08496.5 EIM83039.1 - 8.9 6.0 11.9 19 5.0 7.3 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF1771 PF08590.5 EIM83040.1 - 0.56 10.2 5.0 1 9.4 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Slu7 PF11708.3 EIM83041.1 - 3.2e-86 288.9 13.2 3.2e-86 288.9 9.1 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EIM83041.1 - 0.038 13.6 0.9 0.077 12.6 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Frankia_peptide PF14407.1 EIM83041.1 - 0.5 10.1 8.4 0.98 9.2 0.0 3.5 3 1 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. SNF2_N PF00176.18 EIM83042.1 - 2.3e-68 230.1 1.1 3.5e-68 229.5 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EIM83042.1 - 9.3e-26 89.9 0.2 3.5e-25 88.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EIM83042.1 - 2.2e-17 62.4 9.8 2.7e-15 55.7 0.1 3.5 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIM83042.1 - 1.8e-14 53.3 0.0 3.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM83042.1 - 4.1e-07 29.9 0.1 3.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM83042.1 - 0.017 15.2 0.0 0.075 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Tfb4 PF03850.9 EIM83043.1 - 2.6e-85 286.0 0.0 3.1e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.13 EIM83044.1 - 3.2e-33 114.8 0.0 9.5e-20 70.5 0.0 2.8 3 0 0 3 3 3 2 Asparaginase TMEM171 PF15471.1 EIM83044.1 - 4.8 5.8 8.8 0.36 9.5 2.7 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 TraT PF05818.7 EIM83045.1 - 0.77 9.1 5.4 1.6 8.0 3.8 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein IF-2B PF01008.12 EIM83046.1 - 4.1e-61 206.4 0.0 4.8e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pectate_lyase_3 PF12708.2 EIM83048.1 - 6.7e-83 278.2 29.6 1.9e-68 230.9 7.0 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIM83048.1 - 1.2e-07 31.0 1.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase TPR_16 PF13432.1 EIM83049.1 - 1.7e-13 50.8 5.2 7.8e-06 26.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83049.1 - 5.7e-11 42.5 5.1 9e-07 29.1 0.2 2.8 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83049.1 - 2.1e-07 30.4 3.2 0.0046 16.5 0.1 2.7 3 0 0 3 3 2 2 TPR repeat TPR_14 PF13428.1 EIM83049.1 - 2.6e-07 30.6 16.5 0.02 15.4 0.1 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83049.1 - 1.7e-05 24.3 2.4 0.018 14.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83049.1 - 0.00026 20.9 0.4 1.6 9.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83049.1 - 0.00039 20.2 0.5 0.2 11.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83049.1 - 0.002 17.8 0.6 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83049.1 - 0.003 17.0 0.1 0.16 11.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIM83049.1 - 0.011 16.0 10.2 0.35 11.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIM83049.1 - 0.012 15.4 5.6 0.023 14.6 1.4 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83049.1 - 0.015 15.7 0.4 89 3.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM83049.1 - 0.016 15.3 0.1 6.3 7.0 0.0 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM83049.1 - 0.068 12.9 0.1 18 5.3 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EIM83049.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.1 EIM83049.1 - 0.33 10.9 6.4 0.72 9.8 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP_transf PF09830.4 EIM83050.1 - 3.2e-15 55.6 0.0 5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase COPI_assoc PF08507.5 EIM83051.1 - 0.014 15.0 1.3 0.056 13.1 0.8 1.9 1 1 0 1 1 1 0 COPI associated protein Herpes_gE PF02480.11 EIM83052.1 - 0.025 12.8 0.0 0.089 11.0 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EIM83052.1 - 0.048 12.2 0.2 0.075 11.6 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1469 PF07332.6 EIM83052.1 - 0.078 12.7 0.5 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Podoplanin PF05808.6 EIM83052.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Podoplanin YcfA PF07927.7 EIM83053.1 - 1.9e-05 24.4 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 YcfA-like protein Clat_adaptor_s PF01217.15 EIM83054.1 - 2.5e-17 62.9 0.1 8.6e-17 61.1 0.0 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Mso1_Sec1_bdg PF14475.1 EIM83054.1 - 0.0038 16.5 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 1 Sec1-binding region of Mso1 Gasdermin PF04598.7 EIM83054.1 - 0.027 13.2 0.2 0.034 12.8 0.2 1.2 1 0 0 1 1 1 0 Gasdermin family Med16 PF11635.3 EIM83056.1 - 2e-08 32.7 0.0 3.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 16 CENP-I PF07778.6 EIM83056.1 - 0.16 10.1 0.1 0.29 9.2 0.1 1.3 1 0 0 1 1 1 0 Mis6 ABC_tran PF00005.22 EIM83057.1 - 4e-34 117.8 0.0 7.4e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIM83057.1 - 9.4e-26 90.8 6.2 1.2e-25 90.4 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EIM83057.1 - 5e-07 29.9 0.0 0.026 14.4 0.0 3.3 2 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EIM83057.1 - 1.1e-05 24.7 0.2 0.00039 19.7 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIM83057.1 - 0.00024 21.1 0.0 0.00062 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM83057.1 - 0.0014 18.7 0.2 0.08 13.0 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIM83057.1 - 0.0016 17.9 0.1 0.004 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIM83057.1 - 0.0034 16.5 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIM83057.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EIM83057.1 - 0.11 12.4 0.3 1.8 8.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IFT57 PF10498.4 EIM83059.1 - 0.088 11.5 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SUR7 PF06687.7 EIM83060.1 - 1.2e-22 80.5 7.5 1.6e-22 80.1 5.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIM83060.1 - 3.5e-05 23.5 8.4 0.00024 20.8 6.0 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EIM83060.1 - 0.008 15.4 1.4 0.086 12.0 0.6 2.0 2 0 0 2 2 2 1 Clc-like Amastin PF07344.6 EIM83060.1 - 0.011 15.3 1.1 0.018 14.6 0.7 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF998 PF06197.8 EIM83060.1 - 0.06 12.6 13.4 0.86 8.8 6.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Tetraspannin PF00335.15 EIM83060.1 - 0.26 10.5 9.9 1 8.6 0.3 2.8 1 1 1 2 2 2 0 Tetraspanin family DUF2628 PF10947.3 EIM83060.1 - 0.82 9.4 6.0 0.47 10.2 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) FtsX PF02687.16 EIM83060.1 - 1.1 9.0 8.6 0.2 11.4 1.3 2.4 2 1 0 2 2 2 0 FtsX-like permease family Acyl_transf_3 PF01757.17 EIM83060.1 - 2.7 6.7 16.7 12 4.5 11.5 1.8 1 1 0 1 1 1 0 Acyltransferase family adh_short PF00106.20 EIM83061.1 - 9.5e-16 58.1 0.6 2.1e-15 57.0 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM83061.1 - 9.5e-09 35.1 0.2 1.6e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM83061.1 - 0.00044 20.0 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HK PF02110.10 EIM83062.1 - 6e-72 241.7 0.7 1.2e-70 237.4 0.5 2.4 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EIM83062.1 - 8.4e-56 187.9 0.1 1.7e-55 186.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EIM83062.1 - 0.0019 17.4 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PcrB PF01884.12 EIM83062.1 - 0.036 13.3 0.1 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 PcrB family Alpha-amylase PF00128.19 EIM83063.1 - 3.6e-61 207.2 1.2 4.8e-61 206.8 0.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIM83063.1 - 1.1e-18 67.0 0.3 2.3e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 EIM83063.1 - 0.01 14.7 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Hemerythrin PF01814.18 EIM83064.1 - 8.7e-16 58.2 2.5 1e-15 58.0 1.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Caps_synth PF05704.7 EIM83064.1 - 0.049 12.7 0.0 8 5.5 0.0 2.1 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein DUF1996 PF09362.5 EIM83065.1 - 3.8e-66 223.1 2.1 3.8e-66 223.1 1.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) TATR PF03430.8 EIM83065.1 - 1.4 7.4 5.5 2 6.9 3.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator F-box-like PF12937.2 EIM83066.1 - 0.0011 18.6 0.1 0.0056 16.3 0.1 2.2 1 0 0 1 1 1 1 F-box-like DUF3552 PF12072.3 EIM83066.1 - 0.047 12.9 5.6 0.069 12.3 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PhyH PF05721.8 EIM83067.1 - 4.9e-48 163.9 0.0 5.9e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2461 PF09365.5 EIM83067.1 - 0.043 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) TPR_12 PF13424.1 EIM83068.1 - 3.7e-37 126.1 24.8 3.9e-08 33.1 0.1 7.8 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 EIM83068.1 - 3.7e-37 125.1 35.0 1.1e-05 25.1 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83068.1 - 2.1e-17 61.5 14.0 0.35 10.8 0.0 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc5 PF12862.2 EIM83068.1 - 1.5e-13 50.3 12.5 0.88 9.4 0.0 9.3 2 2 6 8 8 8 4 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 EIM83068.1 - 5.8e-13 48.2 16.8 0.0022 17.5 0.9 7.3 3 2 6 9 9 9 7 TPR repeat TPR_6 PF13174.1 EIM83068.1 - 2.1e-10 40.3 1.9 1.1 9.8 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM83068.1 - 3.5e-09 36.4 21.1 0.52 11.1 0.0 9.8 6 3 3 9 9 8 2 Tetratricopeptide repeat DUF3856 PF12968.2 EIM83068.1 - 3.4e-08 33.4 8.2 0.056 13.2 0.0 5.9 3 2 4 7 7 7 3 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 EIM83068.1 - 6.7e-08 32.9 29.8 0.3 11.8 1.6 8.5 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83068.1 - 1.9e-07 30.3 0.7 18 5.3 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat NACHT PF05729.7 EIM83068.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain ImpA-rel_N PF06812.7 EIM83068.1 - 0.00036 20.2 0.0 0.64 9.8 0.0 4.4 4 0 0 4 4 3 1 ImpA-related N-terminal TPR_1 PF00515.23 EIM83068.1 - 0.0011 18.4 9.6 8 6.2 0.0 7.7 10 0 0 10 10 9 1 Tetratricopeptide repeat DUF3366 PF11846.3 EIM83068.1 - 0.0028 17.5 0.0 1.3 8.8 0.0 4.0 1 1 1 3 3 3 1 Domain of unknown function (DUF3366) TPR_17 PF13431.1 EIM83068.1 - 0.0055 16.8 11.4 6.7 7.1 0.0 7.4 10 0 0 10 10 8 1 Tetratricopeptide repeat MIT PF04212.13 EIM83068.1 - 0.0081 16.0 2.2 25 4.8 0.0 5.4 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain C2 PF00168.25 EIM83069.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain 6PGD PF00393.14 EIM83070.1 - 1.4e-66 224.6 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIM83070.1 - 1e-29 103.5 0.1 1.5e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EIM83070.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MR_MLE_N PF02746.11 EIM83070.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Lipase_3 PF01764.20 EIM83071.1 - 6.5e-30 103.5 0.1 9e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 EIM83071.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 EIM83071.1 - 0.031 13.6 0.1 0.25 10.6 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.20 EIM83072.1 - 2.6e-69 233.2 0.0 3.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83072.1 - 4.2e-37 127.6 0.0 5.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIM83072.1 - 1.4e-15 57.1 0.2 2.6e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 FHA domain APH PF01636.18 EIM83072.1 - 9.2e-06 25.5 0.0 0.0012 18.6 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM83072.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIM83072.1 - 0.00022 20.2 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM83072.1 - 0.049 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NmrA PF05368.8 EIM83074.1 - 1.1e-40 139.2 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM83074.1 - 2.7e-10 40.5 0.0 8.5e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM83074.1 - 6.7e-07 28.6 0.0 1.9e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase adh_short PF00106.20 EIM83074.1 - 4e-06 26.8 0.0 1.4e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM83074.1 - 4.6e-05 23.1 0.0 8.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIM83074.1 - 0.0011 19.0 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EIM83074.1 - 0.0041 17.0 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 EIM83074.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Semialdhyde_dh PF01118.19 EIM83074.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIM83074.1 - 0.076 12.4 0.0 1.2 8.4 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidohydro_1 PF01979.15 EIM83075.1 - 1.4e-13 51.2 0.3 9.8e-08 32.0 0.0 3.2 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIM83075.1 - 1.5e-13 51.4 0.2 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EIM83075.1 - 3.7e-12 45.8 0.1 1.5e-11 43.8 0.1 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM83075.1 - 1.5e-08 34.3 0.4 0.00011 21.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 EIM83075.1 - 0.0034 16.9 2.2 18 5.1 0.1 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat zf-MYND PF01753.13 EIM83076.1 - 0.00032 20.5 19.2 0.00083 19.1 10.7 2.5 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.11 EIM83077.1 - 1.4e-17 63.4 38.9 1.4e-17 63.4 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF372 PF04036.7 EIM83077.1 - 0.053 13.0 0.2 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF372) DUF747 PF05346.6 EIM83078.1 - 2.8e-112 375.0 0.3 3.5e-112 374.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family ComK PF06338.6 EIM83078.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 ComK protein PsbR PF04725.7 EIM83078.1 - 0.15 12.1 1.1 0.35 10.9 0.7 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR RrnaAD PF00398.15 EIM83080.1 - 2.3e-25 89.1 0.0 3.9e-25 88.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase CASP_C PF08172.7 EIM83081.1 - 1.5e-69 233.8 6.6 1.5e-69 233.8 4.6 3.7 2 1 2 4 4 4 1 CASP C terminal Shugoshin_N PF07558.6 EIM83081.1 - 0.0054 16.4 0.9 0.0054 16.4 0.6 5.0 7 0 0 7 7 7 1 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EIM83081.1 - 0.068 12.7 62.8 0.16 11.5 0.5 5.7 3 1 1 4 4 4 0 IncA protein BSD PF03909.12 EIM83082.1 - 5.1e-21 74.1 0.2 3.3e-13 49.1 0.0 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EIM83082.1 - 6.9e-09 35.2 0.1 1.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF1509 PF07420.6 EIM83083.1 - 3 7.0 6.4 5 6.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) WD40 PF00400.27 EIM83084.1 - 1.3e-62 205.5 26.8 1.1e-11 44.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIM83084.1 - 0.00062 18.0 7.7 0.14 10.2 0.4 3.5 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIM83084.1 - 0.02 13.1 0.1 1.6 6.9 0.2 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 EIM83084.1 - 0.03 14.0 1.5 15 5.3 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1416 PF07210.7 EIM83084.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Nucleoporin_N PF08801.6 EIM83084.1 - 0.19 10.4 2.7 2.7 6.6 0.2 2.9 2 1 1 3 3 3 0 Nup133 N terminal like LSM PF01423.17 EIM83087.1 - 4.1e-11 42.2 0.3 5.3e-11 41.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIM83087.1 - 0.014 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain E3_binding PF02817.12 EIM83087.1 - 0.026 14.1 0.2 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain COG2 PF06148.6 EIM83088.1 - 2.4e-29 101.8 3.5 5.1e-29 100.8 0.9 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EIM83088.1 - 4.4e-21 75.2 0.0 4.6e-20 71.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 EIM83088.1 - 0.0027 17.5 0.2 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 PB1 PF00564.19 EIM83088.1 - 0.79 9.4 4.7 8.5 6.1 0.1 3.6 4 0 0 4 4 4 0 PB1 domain Vps8 PF12816.2 EIM83089.1 - 8.7e-66 220.9 0.0 6.1e-65 218.1 0.0 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EIM83089.1 - 0.0019 17.8 0.2 0.06 12.9 0.1 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS PQQ_3 PF13570.1 EIM83089.1 - 0.021 15.0 0.1 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain PhdYeFM_antitox PF02604.14 EIM83089.1 - 0.17 11.4 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Voltage_CLC PF00654.15 EIM83090.1 - 4e-95 318.8 19.4 1.2e-94 317.3 11.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel UPF0233 PF06781.7 EIM83090.1 - 0.0057 16.2 0.9 7.3 6.2 0.1 3.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0233) CBS PF00571.23 EIM83090.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 CBS domain E1-E2_ATPase PF00122.15 EIM83090.1 - 0.24 10.3 1.7 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase Fungal_trans PF04082.13 EIM83091.1 - 3.5e-26 91.6 0.0 5.5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM83091.1 - 8.1e-09 35.2 10.1 1.4e-08 34.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EIM83092.1 - 0.0013 18.4 0.6 0.0013 18.4 0.4 3.2 5 1 0 5 5 5 1 F-box-like F-box PF00646.28 EIM83092.1 - 0.15 11.7 5.9 0.37 10.5 0.1 3.0 2 1 0 2 2 2 0 F-box domain PseudoU_synth_2 PF00849.17 EIM83093.1 - 9e-33 113.4 0.3 2.7e-32 111.8 0.2 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase GLTSCR1 PF15249.1 EIM83094.1 - 2.3e-21 75.9 0.5 4e-21 75.1 0.4 1.4 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region TPR_1 PF00515.23 EIM83095.1 - 1.3e-31 106.8 10.9 7.9e-06 25.2 0.7 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83095.1 - 3.3e-26 90.7 18.4 9.9e-10 37.9 1.2 6.1 4 1 1 6 6 6 5 TPR repeat TPR_2 PF07719.12 EIM83095.1 - 5.7e-26 88.3 15.8 0.00035 20.2 0.0 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat APC8 PF04049.8 EIM83095.1 - 2.1e-20 72.9 0.0 1.1e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 EIM83095.1 - 1.3e-18 65.3 6.0 0.01 15.5 0.0 7.4 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM83095.1 - 6.9e-17 60.4 12.4 0.0017 18.8 0.0 7.6 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83095.1 - 8.6e-16 58.1 8.3 2.9e-06 27.7 0.2 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83095.1 - 6.6e-13 48.3 21.7 3.7e-05 23.5 1.1 6.3 3 1 5 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83095.1 - 4.3e-10 38.9 9.8 0.42 10.9 0.2 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83095.1 - 3.3e-09 35.8 11.1 0.032 14.0 0.1 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83095.1 - 1.5e-08 34.8 14.2 0.77 10.1 0.2 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIM83095.1 - 1.1e-07 31.5 4.0 0.012 15.4 0.7 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIM83095.1 - 6.8e-05 22.0 6.3 0.00039 19.5 3.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83095.1 - 8.6e-05 22.7 13.8 8.4 7.1 0.2 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM83095.1 - 0.0001 22.3 15.4 0.012 15.7 2.6 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EIM83095.1 - 0.0055 16.5 1.5 1.6 8.6 0.2 3.1 3 1 0 3 3 2 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EIM83095.1 - 0.023 14.4 3.5 0.12 12.1 0.2 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.5 EIM83095.1 - 0.034 12.9 0.1 1.4 7.5 0.0 2.7 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3210 PF11489.3 EIM83095.1 - 0.051 12.2 0.1 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) FAT PF02259.18 EIM83095.1 - 0.25 10.2 4.5 5.9 5.7 0.9 3.1 1 1 2 3 3 3 0 FAT domain BTAD PF03704.12 EIM83095.1 - 0.48 10.7 7.1 7 6.9 1.8 2.7 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Alg14 PF08660.6 EIM83096.1 - 4.4e-49 166.7 0.0 5.4e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like zf-CCCH PF00642.19 EIM83097.1 - 6.6e-14 51.1 15.3 3.7e-07 29.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIM83097.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM83097.1 - 0.0094 15.5 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EIM83098.1 - 1.3e-07 31.4 5.8 2.2e-07 30.6 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 EIM83099.1 - 9.2e-14 50.9 0.1 6.4e-08 32.2 0.0 3.2 2 1 0 2 2 2 2 Mitochondrial carrier protein ABC_membrane_2 PF06472.10 EIM83099.1 - 0.014 14.5 0.8 0.049 12.7 0.0 2.2 3 0 0 3 3 3 0 ABC transporter transmembrane region 2 NfeD PF01957.13 EIM83099.1 - 0.031 14.4 0.0 0.031 14.4 0.0 2.8 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Claudin_3 PF06653.6 EIM83099.1 - 0.17 11.6 2.0 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Tight junction protein, Claudin-like SNF2_N PF00176.18 EIM83101.1 - 1.3e-50 171.9 0.0 2e-44 151.6 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM83101.1 - 3.9e-14 52.2 0.0 1.4e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_3 PF12836.2 EIM83101.1 - 4.3e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DEAD PF00270.24 EIM83101.1 - 0.00041 19.8 0.0 0.002 17.6 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Sybindin PF04099.7 EIM83102.1 - 5.4e-20 71.5 0.0 7.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EIM83102.1 - 0.041 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF1168 PF06658.7 EIM83103.1 - 1.4e-37 128.4 14.6 2.2e-37 127.7 10.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Totivirus_coat PF05518.6 EIM83103.1 - 0.8 7.4 3.5 0.54 8.0 1.5 1.3 1 1 0 1 1 1 0 Totivirus coat protein RNase_H2-Ydr279 PF09468.5 EIM83103.1 - 2.3 7.3 5.3 3.3 6.8 3.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ribosomal_S8e PF01201.17 EIM83104.1 - 4e-39 133.7 3.4 7.2e-39 132.9 2.3 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EIM83104.1 - 0.071 13.0 0.6 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 Mer2 DUF3959 PF13105.1 EIM83104.1 - 1.7 7.9 5.3 0.23 10.7 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) Yip1 PF04893.12 EIM83105.1 - 4.4e-07 29.5 10.3 6.3e-07 29.0 7.1 1.3 1 0 0 1 1 1 1 Yip1 domain UPF0203 PF05254.7 EIM83107.1 - 0.0099 15.7 0.4 0.5 10.2 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 EIM83107.1 - 0.016 15.1 0.3 0.019 14.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EIM83107.1 - 0.032 14.2 0.6 0.054 13.5 0.4 1.4 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF1746 PF08508.5 EIM83108.1 - 1.9e-08 34.2 2.2 4.7e-08 32.9 1.5 1.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HeH PF12949.2 EIM83109.1 - 2.7e-07 30.0 0.4 5.6e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain Rho_N PF07498.7 EIM83109.1 - 0.0078 15.9 0.2 0.0078 15.9 0.1 2.2 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain SAP PF02037.22 EIM83109.1 - 0.08 12.4 1.3 0.44 10.1 0.2 2.7 2 1 0 2 2 2 0 SAP domain Armet PF10208.4 EIM83109.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Apc15p PF05841.6 EIM83109.1 - 0.93 10.2 7.3 0.2 12.3 0.6 2.2 2 0 0 2 2 2 0 Apc15p protein TFIIA PF03153.8 EIM83109.1 - 9.3 6.0 12.9 13 5.5 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBFB_NFYA PF02045.10 EIM83110.1 - 2.4e-29 101.6 7.4 3.7e-29 101.0 5.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_S13 PF00416.17 EIM83112.1 - 4e-41 139.7 1.1 4.9e-41 139.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIM83112.1 - 0.0049 15.4 0.0 0.0055 15.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SOG2 PF10428.4 EIM83112.1 - 0.033 12.8 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HHH_6 PF14579.1 EIM83112.1 - 0.033 14.2 0.2 0.11 12.5 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif Rotavirus_VP1 PF12289.3 EIM83112.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein tRNA-synt_2c PF01411.14 EIM83113.1 - 2.3e-214 712.7 0.3 3.2e-214 712.2 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIM83113.1 - 1.5e-15 56.7 0.2 3.5e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EIM83113.1 - 0.00015 21.4 1.2 0.00015 21.4 0.8 2.2 2 0 0 2 2 2 1 DHHA1 domain CLASP_N PF12348.3 EIM83114.1 - 2.8e-20 72.6 0.2 3.4e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 EIM83114.1 - 0.0037 17.2 0.0 0.0037 17.2 0.0 2.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EIM83114.1 - 0.035 14.3 0.3 0.091 13.0 0.2 1.9 1 1 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.1 EIM83114.1 - 0.1 13.1 0.1 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat Flu_NS2 PF00601.14 EIM83117.1 - 0.21 11.7 0.8 0.44 10.7 0.5 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) ENOD40 PF08247.6 EIM83117.1 - 0.64 9.9 0.1 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 ENOD40 protein Rbsn PF11464.3 EIM83117.1 - 0.88 9.1 3.2 32 4.2 0.1 3.3 3 0 0 3 3 3 0 Rabenosyn Rab binding domain zf-B_box PF00643.19 EIM83119.1 - 0.0066 16.3 8.6 0.019 14.8 5.9 1.8 1 0 0 1 1 1 1 B-box zinc finger Tet_JBP PF12851.2 EIM83120.1 - 5.3e-07 29.0 0.0 8.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM83120.1 - 0.062 13.8 0.0 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Herpes_DNAp_acc PF04929.7 EIM83121.1 - 0.64 8.9 9.4 0.03 13.2 2.5 1.7 2 1 0 2 2 2 0 Herpes DNA replication accessory factor Herpes_UL32 PF06070.6 EIM83121.1 - 0.74 8.1 16.0 0.97 7.8 11.1 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Nucleo_P87 PF07267.6 EIM83123.1 - 0.66 8.6 8.7 0.85 8.2 6.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CENP-B_dimeris PF09026.5 EIM83123.1 - 6.8 7.0 14.0 16 5.8 9.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.21 EIM83124.1 - 0.0048 17.1 0.5 0.0048 17.1 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM83124.1 - 0.09 13.1 0.3 0.09 13.1 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Pheromone PF08015.6 EIM83124.1 - 4.8 8.0 8.8 1.3 9.9 3.5 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone Peptidase_C48 PF02902.14 EIM83125.1 - 1.4e-07 31.4 2.0 2.7e-07 30.4 1.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HTH_29 PF13551.1 EIM83126.1 - 0.0031 17.6 0.1 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIM83126.1 - 0.019 14.8 0.4 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase RHH_1 PF01402.16 EIM83126.1 - 0.12 12.3 0.4 8.2 6.4 0.0 3.2 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family HTH_Tnp_4 PF13613.1 EIM83129.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.1 EIM83130.1 - 6.4e-05 22.5 0.0 6.5e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EIM83130.1 - 0.0041 16.6 0.0 0.0041 16.6 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain Dimer_Tnp_hAT PF05699.9 EIM83132.1 - 7.2e-08 31.9 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0147 PF03685.8 EIM83132.1 - 0.083 12.7 0.1 0.82 9.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) CAP_GLY PF01302.20 EIM83134.1 - 8.5e-19 67.0 1.6 1.4e-18 66.3 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 EIM83134.1 - 0.00047 19.4 0.9 0.00047 19.4 0.6 4.7 3 1 2 5 5 5 2 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 EIM83134.1 - 0.39 10.5 2.6 8.1 6.2 0.1 3.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-CCHC_3 PF13917.1 EIM83134.1 - 2 8.2 5.3 11 5.8 0.6 3.2 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 EIM83134.1 - 3.1 7.8 6.8 0.51 10.3 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle UbiA PF01040.13 EIM83135.1 - 0.029 13.5 0.8 0.059 12.5 0.4 1.6 1 1 0 1 1 1 0 UbiA prenyltransferase family GMC_oxred_C PF05199.8 EIM83135.1 - 0.078 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 GMC oxidoreductase eIF-3c_N PF05470.7 EIM83136.1 - 3.2e-179 596.8 25.2 3.2e-179 596.8 17.5 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EIM83136.1 - 2.4e-13 50.3 0.0 1.8e-12 47.4 0.0 2.5 2 1 0 2 2 2 1 PCI domain Hexapep PF00132.19 EIM83137.1 - 6e-09 35.0 4.2 0.008 15.6 0.0 3.7 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EIM83137.1 - 4.7e-07 29.3 0.0 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIM83137.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIM83137.1 - 0.3 10.6 8.1 1.2 8.8 4.5 2.6 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 EIM83138.1 - 6.3e-65 218.9 0.0 7.2e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83138.1 - 7.5e-46 156.2 0.0 1.1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM83138.1 - 7.3e-06 25.1 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM83138.1 - 0.00093 18.9 0.0 0.085 12.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIM83138.1 - 0.0076 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIM83138.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.15 EIM83139.1 - 7.3e-71 236.9 0.0 8.7e-71 236.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIM83139.1 - 6.6e-06 26.0 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM83139.1 - 4.3e-05 24.3 0.0 6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM83139.1 - 0.00033 20.9 0.1 0.00058 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIM83139.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EIM83139.1 - 0.0057 15.8 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EIM83139.1 - 0.027 14.7 0.0 0.042 14.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EIM83139.1 - 0.031 14.6 0.0 0.036 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM83139.1 - 0.095 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 EIM83139.1 - 0.13 11.8 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.1 EIM83139.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EIM83140.1 - 7.3e-50 168.5 0.0 8.6e-50 168.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM83140.1 - 3.6e-18 66.1 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM83140.1 - 6.3e-06 25.5 0.0 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM83140.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_C15 PF01470.12 EIM83141.1 - 5.4e-05 23.1 0.0 0.49 10.2 0.0 3.0 2 1 0 2 2 2 2 Pyroglutamyl peptidase MgsA_C PF12002.3 EIM83142.1 - 2.4e-57 193.2 0.2 4.3e-57 192.4 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EIM83142.1 - 1.1e-16 61.2 0.1 3.7e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM83142.1 - 5.3e-13 48.5 0.0 1.2e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIM83142.1 - 1.1e-07 31.6 0.1 5.9e-06 26.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM83142.1 - 1.4e-06 28.4 0.6 0.00028 21.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EIM83142.1 - 4.8e-06 26.1 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EIM83142.1 - 7.9e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIM83142.1 - 1.6e-05 24.5 0.3 1.6 8.1 0.0 3.4 3 1 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EIM83142.1 - 1.7e-05 24.8 2.4 0.0025 17.8 0.1 3.2 1 1 2 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EIM83142.1 - 6.2e-05 22.2 0.2 0.071 12.2 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIM83142.1 - 7.4e-05 23.5 0.0 0.00027 21.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIM83142.1 - 8.3e-05 22.6 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIM83142.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EIM83142.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM83142.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIM83142.1 - 0.0015 18.4 0.0 0.0052 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EIM83142.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EIM83142.1 - 0.0054 17.0 0.0 0.015 15.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EIM83142.1 - 0.0089 15.7 0.1 2.3 7.8 0.0 2.5 1 1 1 2 2 2 1 Archaeal ATPase AAA_3 PF07726.6 EIM83142.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIM83142.1 - 0.012 15.2 0.0 0.12 12.0 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 EIM83142.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EIM83142.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIM83142.1 - 0.031 14.0 0.1 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EIM83142.1 - 0.041 13.2 0.3 0.13 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM83142.1 - 0.045 13.4 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EIM83142.1 - 0.054 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EIM83142.1 - 0.059 12.2 0.0 0.14 10.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 EIM83142.1 - 0.068 11.8 0.0 0.22 10.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EIM83142.1 - 0.097 12.4 0.1 8.5 6.1 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 EIM83142.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.1 EIM83142.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIM83142.1 - 0.19 10.6 0.0 0.53 9.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TRP PF06011.7 EIM83143.1 - 3.2e-68 230.2 19.8 4.6e-68 229.8 13.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EIM83143.1 - 7.8e-27 94.0 0.6 1.3e-26 93.3 0.4 1.3 1 0 0 1 1 1 1 ML-like domain CytochromB561_N PF09786.4 EIM83143.1 - 0.0045 15.5 0.0 0.011 14.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome B561, N terminal Amidohydro_4 PF13147.1 EIM83144.1 - 1.1e-17 65.0 8.9 3.1e-17 63.4 1.5 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIM83144.1 - 2.4e-09 37.3 0.5 6.6e-06 26.0 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIM83144.1 - 5.8e-09 35.6 0.3 2.1e-07 30.6 0.1 2.9 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM83144.1 - 0.00059 19.1 5.3 0.00082 18.7 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family FAD_binding_5 PF00941.16 EIM83144.1 - 0.18 11.2 1.9 0.53 9.7 1.3 1.7 1 1 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase F-box-like PF12937.2 EIM83145.1 - 1.1e-15 57.0 2.1 2.1e-08 33.7 0.2 3.9 3 0 0 3 3 3 3 F-box-like F-box PF00646.28 EIM83145.1 - 3.2e-05 23.4 8.1 0.0061 16.1 0.3 3.8 3 0 0 3 3 3 2 F-box domain DUF972 PF06156.8 EIM83146.1 - 0.026 14.8 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) F-box-like PF12937.2 EIM83148.1 - 8.3e-07 28.6 0.9 8.3e-07 28.6 0.6 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIM83148.1 - 0.025 14.2 0.0 0.14 11.8 0.0 2.3 1 0 0 1 1 1 0 F-box domain XPA_N PF01286.13 EIM83150.1 - 0.0049 16.5 1.3 0.0089 15.6 0.9 1.4 1 0 0 1 1 1 1 XPA protein N-terminal Cyclin PF08613.6 EIM83152.1 - 3.1e-10 40.6 0.0 6.2e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 EIM83152.1 - 0.0008 18.9 0.4 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribonuc_red_sm PF00268.16 EIM83154.1 - 4.6e-103 344.0 0.2 5.5e-103 343.8 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-HC5HC2H_2 PF13832.1 EIM83159.1 - 0.052 13.5 0.2 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Chlam_PMP PF02415.12 EIM83159.1 - 0.77 10.1 4.0 2.7 8.4 2.8 2.0 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glyco_hydro_61 PF03443.9 EIM83161.1 - 6e-78 261.6 0.0 6e-78 261.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 DUF4551 PF15087.1 EIM83161.1 - 2.1 6.5 9.4 2.8 6.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) peroxidase PF00141.18 EIM83162.1 - 2e-25 89.6 0.0 3.7e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EIM83162.1 - 1.8e-23 82.1 2.3 3.4e-23 81.3 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) ABC_tran PF00005.22 EIM83163.1 - 3.2e-18 66.3 0.0 1.9e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EIM83163.1 - 3.8e-16 59.3 15.5 1.7e-09 37.4 0.2 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 EIM83163.1 - 0.00011 22.3 0.0 0.51 10.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.1 EIM83163.1 - 0.0032 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIM83163.1 - 0.0076 16.5 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIM83163.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EIM83163.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF972 PF06156.8 EIM83165.1 - 0.019 15.3 3.8 0.019 15.3 2.7 5.6 3 1 3 6 6 6 0 Protein of unknown function (DUF972) WEMBL PF05701.6 EIM83165.1 - 0.031 12.7 54.3 0.046 12.1 5.9 3.5 2 1 1 3 3 3 0 Weak chloroplast movement under blue light CN_hydrolase PF00795.17 EIM83166.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Cortex-I_coil PF09304.5 EIM83166.1 - 0.14 12.1 1.1 0.2 11.7 0.7 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil HNH_2 PF13391.1 EIM83167.1 - 4e-08 32.9 0.1 1.1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease ubiquitin PF00240.18 EIM83168.1 - 1.2e-19 69.4 0.2 2.1e-19 68.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM83168.1 - 1.4e-10 40.6 0.7 2.1e-10 40.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EIM83168.1 - 1.5e-10 40.5 0.1 3.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 EIM83168.1 - 2.2e-06 27.7 0.1 3.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIM83168.1 - 0.012 15.4 0.1 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 EIM83168.1 - 0.013 14.9 9.2 0.04 13.3 5.1 2.6 1 1 1 2 2 2 0 XPC-binding domain Tax PF02959.11 EIM83168.1 - 0.073 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 HTLV Tax Glyco_hydro_18 PF00704.23 EIM83169.1 - 9.8e-58 196.2 3.5 2.2e-57 195.0 2.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.19 EIM83169.1 - 9e-13 48.0 0.0 1.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF1449 PF07290.6 EIM83171.1 - 0.019 14.3 1.8 0.027 13.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1449) AAA_10 PF12846.2 EIM83172.1 - 4.8e-07 29.5 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Zot PF05707.7 EIM83172.1 - 1.1e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA PF00004.24 EIM83172.1 - 0.0046 17.1 0.1 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2435 PF10363.4 EIM83172.1 - 0.058 13.2 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Alpha_GJ PF03229.8 EIM83173.1 - 0.0011 19.3 0.9 0.0022 18.3 0.6 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J Gly-zipper_Omp PF13488.1 EIM83173.1 - 0.003 17.1 1.0 0.0063 16.1 0.7 1.4 1 0 0 1 1 1 1 Glycine zipper adh_short PF00106.20 EIM83174.1 - 3.9e-07 30.1 2.4 0.013 15.4 0.8 2.2 1 1 1 2 2 2 2 short chain dehydrogenase Glycos_transf_1 PF00534.15 EIM83174.1 - 0.038 13.4 0.1 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fungal_lectin PF07938.7 EIM83175.1 - 0.018 14.3 0.3 0.039 13.2 0.2 1.5 1 0 0 1 1 1 0 Fungal fucose-specific lectin ADH_N PF08240.7 EIM83176.1 - 0.033 13.9 1.2 0.056 13.2 0.8 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_N PF08240.7 EIM83178.1 - 3e-26 91.3 5.5 4.9e-26 90.6 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM83178.1 - 3.3e-25 88.1 0.2 5.8e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM83178.1 - 0.0014 19.4 0.0 0.0026 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF87 PF01935.12 EIM83179.1 - 0.0021 17.9 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 EIM83179.1 - 0.037 13.4 0.0 0.45 9.8 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain MIP PF00230.15 EIM83180.1 - 1.9e-45 155.0 15.2 2.3e-45 154.8 10.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF423 PF04241.10 EIM83180.1 - 1.4 8.8 9.4 0.62 10.0 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF423) zf-MYND PF01753.13 EIM83181.1 - 8.1e-08 32.0 12.0 2.3e-07 30.5 8.3 1.8 1 1 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EIM83181.1 - 0.17 11.1 2.7 0.45 9.8 1.3 2.0 2 0 0 2 2 2 0 Life-span regulatory factor DUF1191 PF06697.7 EIM83182.1 - 0.0044 15.8 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EIM83182.1 - 0.0071 14.6 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EIM83182.1 - 0.014 14.8 0.3 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EIM83182.1 - 0.029 13.7 0.5 0.058 12.7 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EIM83182.1 - 0.037 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.6 EIM83182.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF4328 PF14219.1 EIM83182.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) stn_TNFRSF12A PF12191.3 EIM83182.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1180 PF06679.7 EIM83182.1 - 0.25 11.1 1.8 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1649 PF07855.7 EIM83183.1 - 2.1e-33 115.2 0.0 2.4e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF603 PF04645.7 EIM83184.1 - 0.13 12.1 3.2 0.17 11.7 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF603 CENP-F_leu_zip PF10473.4 EIM83184.1 - 0.3 10.9 20.1 0.057 13.2 7.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EIM83184.1 - 0.48 8.8 9.3 0.55 8.6 5.9 1.4 1 1 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 EIM83184.1 - 1.5 8.5 16.6 0.2 11.4 0.2 3.9 2 1 0 3 3 3 0 Prefoldin subunit DivIVA PF05103.8 EIM83184.1 - 1.7 8.6 17.8 1.2 9.2 0.2 3.2 2 1 1 3 3 3 0 DivIVA protein Syntaxin-6_N PF09177.6 EIM83184.1 - 2.3 8.6 7.5 10 6.6 0.1 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EIM83184.1 - 3.7 7.4 20.8 8.2 6.3 2.3 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EIM83184.1 - 9.6 4.7 14.6 1 7.9 5.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein SKN1 PF03935.10 EIM83185.1 - 8.4e-178 591.6 7.8 9.4e-178 591.4 5.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Herpes_BLRF2 PF05812.7 EIM83187.1 - 0.0041 16.9 1.1 0.32 10.8 0.2 2.6 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein CCDC92 PF14916.1 EIM83187.1 - 0.0074 15.8 0.6 0.55 9.8 0.1 2.6 2 0 0 2 2 2 1 Coiled-coil domain of unknown function FLgD_tudor PF13861.1 EIM83187.1 - 0.099 12.6 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 FlgD Tudor-like domain TSC22 PF01166.13 EIM83187.1 - 0.19 11.7 2.0 20 5.2 0.4 2.7 2 1 0 2 2 2 0 TSC-22/dip/bun family Kinesin-relat_1 PF12711.2 EIM83187.1 - 0.19 12.1 4.4 2 8.8 1.1 2.4 2 0 0 2 2 2 0 Kinesin motor TBPIP PF07106.8 EIM83187.1 - 0.33 10.4 6.1 5.5 6.4 1.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EIM83187.1 - 0.48 10.1 5.8 0.65 9.7 3.3 1.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EIM83187.1 - 0.65 10.3 10.7 10 6.5 5.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIM83187.1 - 0.69 9.4 8.2 7.3 6.1 1.6 3.2 2 1 1 3 3 3 0 Septum formation initiator NYD-SP28_assoc PF14775.1 EIM83187.1 - 1.7 8.3 11.0 0.12 12.1 1.8 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 EIM83187.1 - 4.1 7.3 10.4 0.066 13.0 1.4 2.3 3 0 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 EIM83187.1 - 5.1 6.6 6.2 11 5.5 4.3 1.5 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 EIM83187.1 - 8 6.5 10.8 3.8 7.5 1.7 3.1 1 1 2 3 3 3 0 bZIP transcription factor MARVEL PF01284.18 EIM83188.1 - 1.1e-11 44.7 0.0 0.00013 21.7 0.6 2.2 2 0 0 2 2 2 2 Membrane-associating domain PBP1_TM PF14812.1 EIM83188.1 - 0.00061 20.0 18.1 0.013 15.8 3.0 3.8 4 0 0 4 4 4 2 Transmembrane domain of transglycosylase PBP1 at N-terminal ATG27 PF09451.5 EIM83188.1 - 0.00088 18.5 3.2 0.094 11.9 0.2 2.4 2 0 0 2 2 2 2 Autophagy-related protein 27 DUF2946 PF11162.3 EIM83188.1 - 0.0024 18.0 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2946) DUF912 PF06024.7 EIM83188.1 - 0.018 15.0 0.0 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2189 PF09955.4 EIM83188.1 - 0.035 14.0 0.8 0.035 14.0 0.6 3.1 4 0 0 4 4 4 0 Predicted integral membrane protein (DUF2189) SDA1 PF05285.7 EIM83188.1 - 0.043 13.1 3.3 0.15 11.2 0.6 2.1 2 0 0 2 2 2 0 SDA1 DUF3328 PF11807.3 EIM83188.1 - 0.056 13.1 0.2 3 7.4 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3328) TRAP_alpha PF03896.11 EIM83188.1 - 0.083 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 EIM83188.1 - 0.12 11.9 8.4 2.2 7.8 3.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region EI24 PF07264.6 EIM83188.1 - 0.22 10.9 9.6 0.14 11.5 1.0 2.9 2 2 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) CDC45 PF02724.9 EIM83188.1 - 1.4 6.8 3.6 0.37 8.7 0.1 1.7 2 0 0 2 2 2 0 CDC45-like protein Aldo_ket_red PF00248.16 EIM83189.1 - 2.1e-36 125.1 0.0 3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MARVEL PF01284.18 EIM83190.1 - 1.2e-10 41.3 17.6 1.5e-10 41.0 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain TPR_10 PF13374.1 EIM83191.1 - 1.1e-43 145.9 0.8 2.5e-15 55.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83191.1 - 5.2e-33 112.8 2.2 1e-16 60.6 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83191.1 - 1.7e-12 46.1 0.5 0.0015 18.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83191.1 - 6.7e-11 41.6 1.3 9.9e-06 25.1 0.0 3.3 3 1 1 4 4 3 2 TPR repeat TPR_2 PF07719.12 EIM83191.1 - 3.6e-10 38.9 3.1 0.0062 16.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83191.1 - 3.3e-09 35.9 1.4 0.00022 20.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83191.1 - 7.2e-07 28.9 0.3 0.032 14.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83191.1 - 9.5e-07 28.1 0.4 0.016 14.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83191.1 - 1.4e-06 28.8 0.0 0.00088 19.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83191.1 - 6.8e-06 26.3 0.3 0.014 15.6 0.3 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83191.1 - 2e-05 24.7 0.2 0.018 15.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 EIM83191.1 - 5.1e-05 22.9 0.2 6 7.0 0.0 4.2 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.1 EIM83191.1 - 6.2e-05 23.2 0.4 0.85 10.4 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF2680 PF10925.3 EIM83191.1 - 0.00018 21.3 0.9 0.7 9.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2680) Apc3 PF12895.2 EIM83191.1 - 0.0017 18.4 0.1 0.064 13.3 0.1 2.5 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EIM83191.1 - 0.0018 18.5 0.0 27 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2664 PF10867.3 EIM83191.1 - 0.038 14.6 1.1 13 6.5 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) TPR_3 PF07720.7 EIM83191.1 - 0.071 12.9 0.0 2.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MARVEL PF01284.18 EIM83193.1 - 2.2e-11 43.7 15.8 2.9e-11 43.3 10.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ribonuc_L-PSP PF01042.16 EIM83194.1 - 1.2e-40 137.9 0.3 1.6e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dor1 PF04124.7 EIM83195.1 - 7.3e-49 166.0 0.0 9.1e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Baculo_PEP_C PF04513.7 EIM83195.1 - 0.17 11.6 0.9 0.78 9.5 0.7 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.7 EIM83196.1 - 6.3e-06 24.8 0.0 0.00033 19.2 0.0 2.0 2 0 0 2 2 2 2 Dor1-like family TAFH PF07531.9 EIM83196.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF Vps51 PF08700.6 EIM83198.1 - 3e-15 55.8 0.6 3e-15 55.8 0.4 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EIM83198.1 - 3.2e-06 27.0 1.8 3.2e-06 27.0 1.2 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Dus PF01207.12 EIM83199.1 - 3e-46 157.6 0.0 4.9e-46 156.9 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RNase_H PF00075.19 EIM83201.1 - 1e-10 42.0 0.0 5.7e-10 39.6 0.0 2.2 2 1 0 2 2 2 1 RNase H Pkinase PF00069.20 EIM83201.1 - 0.0028 16.8 0.1 0.033 13.3 0.1 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83201.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase RVT_3 PF13456.1 EIM83201.1 - 0.71 9.6 3.6 2.2 8.1 0.8 2.7 2 1 0 2 2 2 0 Reverse transcriptase-like Pyr_redox_3 PF13738.1 EIM83202.1 - 3.7e-14 53.2 0.0 8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM83202.1 - 4.2e-09 36.2 0.6 1e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EIM83202.1 - 0.00028 19.2 0.0 0.066 11.4 0.0 2.8 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Thi4 PF01946.12 EIM83202.1 - 0.03 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Sel1 PF08238.7 EIM83203.1 - 8.2e-44 147.0 23.8 1.9e-08 34.6 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat Aminotran_1_2 PF00155.16 EIM83206.1 - 4.4e-35 121.3 0.0 5.5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIM83206.1 - 0.17 10.1 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EIM83206.1 - 0.18 10.5 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Abhydrolase_6 PF12697.2 EIM83207.1 - 3e-22 79.6 0.3 4.2e-22 79.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM83207.1 - 4.1e-12 46.0 0.0 8.9e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM83207.1 - 3.7e-09 36.4 0.0 2.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIM83207.1 - 0.0006 19.6 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Acetyltransf_1 PF00583.19 EIM83208.1 - 1.7e-11 43.9 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM83208.1 - 2.7e-08 33.8 0.0 1.2e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM83208.1 - 2.6e-06 27.5 0.0 6.3e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM83208.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIM83208.1 - 0.0006 19.6 0.0 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EIM83208.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.1 EIM83208.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SNF2_N PF00176.18 EIM83210.1 - 3.5e-76 255.8 0.5 6.2e-76 255.0 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EIM83210.1 - 1.4e-39 134.4 2.0 3.6e-39 133.1 0.1 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EIM83210.1 - 4.4e-29 101.1 1.4 4.4e-29 101.1 0.9 3.0 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EIM83210.1 - 1.6e-14 53.4 0.0 5.6e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM83210.1 - 2.1e-07 30.9 0.0 1e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIM83210.1 - 2.3e-06 27.1 0.0 6.5e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIM83210.1 - 3.1e-05 22.9 0.0 6.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.1 EIM83210.1 - 0.00046 20.0 0.3 0.021 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DEAD_2 PF06733.10 EIM83210.1 - 0.0014 18.0 0.1 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 DBINO PF13892.1 EIM83210.1 - 0.0058 16.6 2.3 0.0058 16.6 1.6 3.5 4 0 0 4 4 4 1 DNA-binding domain AhpC-TSA_2 PF13911.1 EIM83212.1 - 1.6e-19 69.9 0.0 2.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIM83212.1 - 2.3e-05 24.0 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM83212.1 - 0.0039 16.7 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EIM83214.1 - 6.7e-21 74.3 0.0 9.4e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF1802 PF08819.6 EIM83214.1 - 0.00041 20.0 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) AhpC-TSA PF00578.16 EIM83214.1 - 0.11 12.2 0.0 2.1 8.0 0.0 2.2 1 1 0 1 1 1 0 AhpC/TSA family AhpC-TSA_2 PF13911.1 EIM83215.1 - 1.6e-22 79.6 0.1 2.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIM83215.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM83215.1 - 1.4e-07 31.1 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EIM83215.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM83215.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.27 EIM83216.1 - 2.1e-38 128.8 30.7 3.4e-11 42.5 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat NACHT PF05729.7 EIM83216.1 - 2e-07 30.8 0.0 1.1e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.7 EIM83216.1 - 0.00014 21.4 0.3 3.4 7.4 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EIM83216.1 - 0.00082 19.4 0.0 0.0026 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EIM83216.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EIM83216.1 - 0.042 14.0 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF742 PF05331.6 EIM83216.1 - 0.049 13.2 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF742) G-alpha PF00503.15 EIM83217.1 - 3.7e-129 430.8 0.0 4.7e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM83217.1 - 1.3e-13 50.5 0.2 6.1e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIM83217.1 - 0.00099 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EIM83217.1 - 0.0046 16.1 0.3 2.1 7.4 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM83217.1 - 0.035 13.5 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.4 EIM83217.1 - 0.04 12.8 0.1 0.075 11.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 EIM83217.1 - 0.043 13.9 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 EIM83217.1 - 0.075 12.4 0.0 11 5.3 0.0 2.6 2 1 0 2 2 2 0 Ras family Miro PF08477.8 EIM83217.1 - 0.1 13.1 0.0 1.2 9.6 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein RNase_H PF00075.19 EIM83218.1 - 2.9e-12 47.0 0.0 3.8e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EIM83218.1 - 0.00049 19.8 2.4 0.0018 17.9 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase-like DASH_Ask1 PF08655.5 EIM83219.1 - 3.2e-14 52.4 0.0 5.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 VWA_2 PF13519.1 EIM83220.1 - 1.2e-12 48.2 0.1 1.9e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIM83220.1 - 2.8e-05 23.9 0.0 5.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIM83220.1 - 0.0003 20.6 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 EIM83220.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_28 PF03033.15 EIM83220.1 - 0.066 12.9 0.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Proteasome PF00227.21 EIM83221.1 - 4e-57 192.5 0.0 5.1e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM83221.1 - 1.9e-14 52.6 0.0 3.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADH_N PF08240.7 EIM83222.1 - 3.6e-29 100.7 0.5 5.8e-29 100.0 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM83222.1 - 8.9e-18 64.0 0.1 1.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EIM83222.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GMC_oxred_N PF00732.14 EIM83224.1 - 1.6e-54 185.1 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM83224.1 - 2.9e-36 124.9 0.0 4.8e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM83224.1 - 0.00012 21.1 0.6 0.098 11.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM83224.1 - 0.0004 19.4 0.3 0.0022 16.9 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM83224.1 - 0.0006 19.7 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM83224.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM83224.1 - 0.012 14.1 0.1 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EIM83224.1 - 0.018 13.9 0.3 0.034 13.0 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EIM83224.1 - 0.025 14.4 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM83224.1 - 0.033 12.8 0.3 0.053 12.1 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 EIM83224.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EIM83224.1 - 0.096 13.1 0.1 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.13 EIM83225.1 - 5.7e-09 35.7 11.6 5.7e-09 35.7 8.1 1.8 2 0 0 2 2 2 1 MYND finger UCH PF00443.24 EIM83226.1 - 5e-42 143.8 0.0 4.1e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EIM83226.1 - 3.6e-19 67.9 0.0 1.4e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 A repeated domain in UCH-protein UCH_1 PF13423.1 EIM83226.1 - 4.2e-14 52.6 0.1 1.2e-08 34.8 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EIM83226.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 PUB domain NAD_binding_1 PF00175.16 EIM83228.1 - 1.5e-23 83.4 0.0 2.4e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIM83228.1 - 3.6e-17 62.3 0.0 8.9e-16 57.8 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIM83228.1 - 1.3e-07 31.6 0.0 0.00011 22.2 0.0 2.9 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIM83228.1 - 0.00069 19.5 0.0 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain UbiA PF01040.13 EIM83230.1 - 1.7e-28 99.5 19.1 2.4e-28 99.0 13.0 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family PQQ PF01011.16 EIM83232.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat UPF0184 PF03670.8 EIM83235.1 - 0.39 10.9 3.5 0.45 10.7 2.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) efThoc1 PF11957.3 EIM83236.1 - 1.6e-92 310.6 7.2 1.2e-86 291.2 3.3 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor K_channel_TID PF07941.6 EIM83236.1 - 5.8 7.2 16.7 2.1 8.6 2.5 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TRI9 PF08195.6 EIM83238.1 - 7.1 6.3 6.5 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 TRI9 protein ABC_ATPase PF09818.4 EIM83239.1 - 8.5e-165 548.6 0.0 1.2e-164 548.1 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 EIM83239.1 - 0.003 17.8 0.1 0.003 17.8 0.0 1.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIM83239.1 - 0.0031 16.9 0.7 0.0084 15.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EIM83239.1 - 0.007 15.7 0.0 0.063 12.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain YcfA PF07927.7 EIM83240.1 - 1.5e-05 24.8 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 YcfA-like protein Ribosomal_S15 PF00312.17 EIM83243.1 - 5.8e-18 64.4 0.3 1.1e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 YiiD_Cterm PF09500.5 EIM83244.1 - 2.6 7.5 5.3 6.7 6.2 0.2 2.3 1 1 1 2 2 2 0 Putative thioesterase (yiiD_Cterm) DDE_3 PF13358.1 EIM83246.1 - 2.6e-09 36.9 0.1 2.7e-05 23.9 0.0 3.0 3 1 0 3 3 3 2 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIM83246.1 - 0.16 10.6 1.7 1.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain F-box-like PF12937.2 EIM83249.1 - 4.4e-06 26.3 0.6 9.2e-06 25.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM83249.1 - 0.011 15.3 0.2 0.049 13.2 0.1 2.2 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EIM83249.1 - 0.065 12.8 0.5 1.4 8.6 0.0 3.0 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) ChaC PF04752.7 EIM83252.1 - 2.2e-52 177.6 0.0 2.5e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 EIM83252.1 - 0.0048 17.3 0.1 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family UCR_6-4kD PF08997.5 EIM83252.1 - 0.16 11.7 1.2 5.7 6.7 0.0 2.7 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Beta-lactamase PF00144.19 EIM83254.1 - 5.1e-36 124.3 0.4 2.2e-35 122.2 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 EIM83254.1 - 0.009 15.8 0.2 0.066 13.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Inositol_P PF00459.20 EIM83255.1 - 6.6e-63 212.5 0.0 7.5e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Amidohydro_5 PF13594.1 EIM83256.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase Epimerase PF01370.16 EIM83257.1 - 3.7e-42 144.4 0.0 4.8e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EIM83257.1 - 2.6e-24 84.9 0.0 4.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EIM83257.1 - 8.8e-13 47.5 0.0 2.9e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIM83257.1 - 3.7e-11 42.4 0.0 1.5e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM83257.1 - 1e-09 37.7 0.1 8.8e-09 34.6 0.1 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EIM83257.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM83257.1 - 7.9e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EIM83257.1 - 2.4e-06 26.6 0.0 6.2e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIM83257.1 - 0.001 19.1 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIM83257.1 - 0.042 14.1 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIM83257.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EIM83257.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 EIM83258.1 - 2.3e-35 121.9 25.9 3.1e-35 121.5 18.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1923 PF09083.5 EIM83258.1 - 0.083 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Phageshock_PspD PF09584.5 EIM83258.1 - 0.12 12.0 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) M60-like PF13402.1 EIM83259.1 - 0.066 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60-like family PPC PF04151.10 EIM83259.1 - 8.7 7.4 8.1 42 5.2 5.2 2.5 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Rotamase PF00639.16 EIM83260.1 - 4.3e-24 85.0 0.0 5.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIM83260.1 - 1.9e-20 73.2 0.0 2.4e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EIM83260.1 - 6.7e-08 32.2 0.8 8.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EIM83260.1 - 4.3e-05 24.1 0.0 6.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain CCDC144C PF14915.1 EIM83261.1 - 0.00078 18.4 5.3 0.0014 17.6 3.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region U79_P34 PF03064.11 EIM83261.1 - 0.021 14.3 4.4 0.04 13.4 3.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spc24 PF08286.6 EIM83261.1 - 0.028 14.1 2.0 0.056 13.1 1.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TSC22 PF01166.13 EIM83261.1 - 0.19 11.7 4.1 0.38 10.7 2.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Sec23_trunk PF04811.10 EIM83262.1 - 4.7e-52 176.7 0.0 9.1e-47 159.4 0.0 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIM83262.1 - 3.9e-20 71.2 0.0 1.2e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIM83262.1 - 1.5e-15 56.4 6.1 2.8e-15 55.5 4.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIM83262.1 - 2.2e-14 53.7 0.0 5.4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIM83262.1 - 9.5e-08 31.6 0.2 2.7e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat WW PF00397.21 EIM83262.1 - 0.0091 15.8 0.2 0.0091 15.8 0.2 2.6 2 0 0 2 2 2 1 WW domain NGP1NT PF08153.7 EIM83263.1 - 2.3e-45 153.6 0.7 4e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EIM83263.1 - 1.3e-20 73.4 0.1 3.3e-16 59.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM83263.1 - 1.3e-05 24.4 0.4 0.0001 21.6 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIM83263.1 - 0.0001 21.5 0.5 0.001 18.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIM83263.1 - 0.00034 20.1 3.5 0.0042 16.5 0.1 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EIM83263.1 - 0.0035 16.6 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Enolase_C PF00113.17 EIM83264.1 - 5.9e-149 494.9 0.1 8.1e-149 494.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EIM83264.1 - 1.5e-58 196.4 0.1 2.5e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EIM83264.1 - 0.00029 20.7 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EIM83264.1 - 0.0012 17.7 0.1 0.0029 16.5 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EIM83264.1 - 0.03 14.8 0.0 0.065 13.7 0.0 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_S9 PF00326.16 EIM83266.1 - 5e-44 150.0 0.3 8e-44 149.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM83266.1 - 8.8e-07 28.7 0.1 1.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIM83266.1 - 0.026 13.0 0.1 0.93 7.9 0.0 2.1 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) IBN_N PF03810.14 EIM83267.1 - 1e-11 44.5 0.0 7.7e-11 41.7 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 EIM83267.1 - 2.7e-07 29.2 0.2 0.0011 17.3 0.1 2.8 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus ParcG PF10274.4 EIM83267.1 - 0.00034 20.5 0.4 2.2 8.1 0.0 3.4 3 0 0 3 3 3 2 Parkin co-regulated protein Xpo1 PF08389.7 EIM83267.1 - 0.0056 16.6 0.7 0.29 11.0 0.0 4.0 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 EIM83267.1 - 0.0087 16.3 2.1 0.7 10.2 0.0 4.6 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EIM83267.1 - 0.012 15.6 2.1 0.2 11.8 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat YcfA PF07927.7 EIM83268.1 - 0.0018 18.1 0.2 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 YcfA-like protein DUF2410 PF10307.4 EIM83268.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) Spo0A_C PF08769.6 EIM83268.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Epimerase PF01370.16 EIM83269.1 - 1.1e-15 57.7 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM83269.1 - 1.3e-07 31.7 0.1 5.6e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM83269.1 - 5.8e-07 28.6 0.1 1.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EIM83269.1 - 8e-06 24.7 0.0 2.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIM83269.1 - 0.0054 16.0 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM83269.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.20 EIM83270.1 - 1.1e-71 241.0 0.0 1.3e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83270.1 - 2e-31 109.0 0.0 2.4e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM83270.1 - 0.00036 19.6 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM83270.1 - 0.00051 19.8 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM83270.1 - 0.0013 17.8 0.0 0.019 13.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EIM83270.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.19 EIM83272.1 - 1.6e-113 379.6 13.8 2e-113 379.3 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM83272.1 - 7.1e-18 64.4 33.1 2.8e-13 49.3 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VHS PF00790.14 EIM83273.1 - 0.0089 15.6 0.1 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 VHS domain Poxvirus_B22R_C PF13168.1 EIM83273.1 - 0.025 13.8 0.1 0.051 12.8 0.0 1.4 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal UCH PF00443.24 EIM83274.1 - 8.6e-63 211.9 0.0 9.9e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM83274.1 - 1.2e-35 123.4 0.0 1.9e-35 122.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIM83274.1 - 0.023 14.0 1.4 0.69 9.1 1.6 2.7 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_hydro_47 PF01532.15 EIM83275.1 - 1.1e-145 485.8 0.0 1.2e-145 485.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GMC_oxred_N PF00732.14 EIM83276.1 - 7e-64 215.8 0.0 8.9e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM83276.1 - 3.7e-35 121.3 0.1 8e-35 120.2 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EIM83276.1 - 0.0009 18.2 0.4 0.005 15.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM83276.1 - 0.0015 18.5 0.1 0.0041 17.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM83276.1 - 0.0017 18.4 0.4 0.42 10.6 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM83276.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM83276.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EIM83276.1 - 0.031 13.2 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM83276.1 - 0.2 10.4 4.6 2.3 6.9 0.5 2.5 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.13 EIM83276.1 - 0.24 11.3 1.0 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EIM83276.1 - 0.31 10.8 2.4 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-H2C2_2 PF13465.1 EIM83277.1 - 1.2e-10 41.1 10.3 8.1e-09 35.3 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIM83277.1 - 3.9e-10 39.4 11.9 2.3e-05 24.4 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM83277.1 - 1.8e-09 37.2 11.1 0.00011 22.3 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIM83277.1 - 0.0041 16.9 0.7 0.0041 16.9 0.5 2.3 3 1 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIM83277.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 EIM83277.1 - 0.083 13.1 3.5 6.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM83277.1 - 0.11 12.6 6.3 0.22 11.6 0.8 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 EIM83277.1 - 0.48 10.6 4.9 7.1 6.9 0.1 2.1 1 1 1 2 2 2 0 CHORD TauD PF02668.11 EIM83278.1 - 4.9e-36 124.7 0.0 9.7e-36 123.7 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 EIM83279.1 - 3.2e-46 158.0 0.0 4.7e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GMC_oxred_N PF00732.14 EIM83280.1 - 4.8e-63 213.0 0.0 2.5e-62 210.7 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM83280.1 - 5.3e-35 120.8 0.8 8.5e-35 120.1 0.2 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EIM83280.1 - 0.0013 18.6 0.2 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM83280.1 - 0.0014 17.5 0.4 0.0028 16.6 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM83280.1 - 0.0018 18.2 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM83280.1 - 0.0055 16.7 0.5 0.29 11.1 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM83280.1 - 0.0082 15.0 0.9 1.2 7.8 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EIM83280.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EIM83280.1 - 0.046 12.6 0.2 0.046 12.6 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein EF-hand_1 PF00036.27 EIM83281.1 - 1.5e-25 86.5 18.0 2.9e-09 35.5 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIM83281.1 - 2.5e-24 85.2 13.6 6.3e-12 45.4 3.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIM83281.1 - 3.1e-22 76.4 14.2 1.7e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EIM83281.1 - 3.8e-15 55.2 16.7 4.2e-10 39.0 1.5 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EIM83281.1 - 1.6e-14 52.4 7.5 0.0003 19.9 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EIM83281.1 - 3.2e-10 39.7 1.3 0.00061 19.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIM83281.1 - 8.8e-09 35.0 6.0 0.00039 20.1 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EIM83281.1 - 0.0025 17.4 0.2 0.061 12.8 0.0 2.5 2 1 1 3 3 3 1 Caleosin related protein DUF1636 PF07845.6 EIM83281.1 - 0.01 16.0 0.0 2.5 8.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) DUF3164 PF11363.3 EIM83281.1 - 0.022 14.1 0.3 1.2 8.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) DUF1059 PF06348.6 EIM83281.1 - 0.028 14.2 0.4 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) HTH_29 PF13551.1 EIM83281.1 - 0.11 12.6 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix SPARC_Ca_bdg PF10591.4 EIM83281.1 - 0.14 12.2 3.9 1.3 9.0 0.2 2.4 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MerR-DNA-bind PF09278.6 EIM83281.1 - 0.15 12.4 1.9 17 5.9 0.2 3.3 3 0 0 3 3 3 0 MerR, DNA binding DUF4601 PF15373.1 EIM83281.1 - 0.15 10.8 0.2 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) MgtE_N PF03448.12 EIM83281.1 - 0.79 10.0 6.6 0.36 11.1 1.1 2.4 3 0 0 3 3 3 0 MgtE intracellular N domain zf-C2H2 PF00096.21 EIM83282.1 - 1.5e-12 47.0 6.3 1.4e-05 25.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM83282.1 - 2.3e-10 40.0 3.7 4.4e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM83282.1 - 5.6e-07 29.5 11.0 5e-06 26.5 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM83282.1 - 0.0038 17.0 0.6 0.0038 17.0 0.4 2.0 3 0 0 3 3 3 1 C2H2-type zinc finger Beta-lactamase PF00144.19 EIM83283.1 - 5.7e-42 143.9 0.1 8e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DLH PF01738.13 EIM83284.1 - 3.7e-13 49.2 0.0 4.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM83284.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EIM83285.1 - 2.1e-39 135.2 48.3 8.4e-39 133.2 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_3 PF01596.12 EIM83286.1 - 5.5e-47 159.4 0.0 7e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIM83286.1 - 1.7e-15 57.7 0.0 2.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM83286.1 - 2.3e-08 34.6 0.0 4.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM83286.1 - 1.9e-06 27.9 0.0 3.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM83286.1 - 7.9e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM83286.1 - 6.1e-05 22.6 0.0 9.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIM83286.1 - 0.007 16.8 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIM83286.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.5 EIM83286.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit CPSase_L_D2 PF02786.12 EIM83287.1 - 3e-66 222.7 0.0 5e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIM83287.1 - 2.6e-43 146.6 0.0 7.6e-43 145.0 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIM83287.1 - 3e-31 107.5 0.0 2.6e-30 104.5 0.0 2.3 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EIM83287.1 - 9.3e-13 48.3 0.0 2.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EIM83287.1 - 5.2e-11 42.0 8.4 5.2e-11 42.0 4.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.17 EIM83287.1 - 2.9e-06 26.7 0.0 1.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIM83287.1 - 3.1e-06 26.7 0.0 1.2e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EIM83287.1 - 0.0013 18.3 2.1 0.0086 15.7 1.4 2.2 1 1 0 1 1 1 1 Biotin-lipoyl like Toxin_59 PF15537.1 EIM83287.1 - 0.02 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 59 RimK PF08443.6 EIM83287.1 - 0.079 12.4 0.0 0.36 10.2 0.0 2.0 1 1 0 1 1 1 0 RimK-like ATP-grasp domain DUF2118 PF09891.4 EIM83287.1 - 1.1 9.0 10.1 5.7 6.6 1.9 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) MFS_1 PF07690.11 EIM83288.1 - 1.3e-41 142.4 46.2 1.5e-41 142.3 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM169 PF15052.1 EIM83288.1 - 0.25 11.2 4.4 0.24 11.2 0.6 2.5 2 0 0 2 2 2 0 TMEM169 protein family Neurensin PF14927.1 EIM83288.1 - 0.48 9.7 3.0 1.1 8.6 0.4 2.7 3 1 0 3 3 3 0 Neurensin DUF2207 PF09972.4 EIM83288.1 - 3.2 6.2 10.2 5.7 5.3 0.0 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) HSCB_C PF07743.8 EIM83289.1 - 2.3e-14 53.5 9.8 4.1e-14 52.7 6.8 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EIM83289.1 - 1.1e-10 41.0 0.4 3.4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 EIM83289.1 - 0.087 12.6 0.5 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Pex24p PF06398.6 EIM83290.1 - 6.5e-13 48.1 0.6 8.6e-13 47.7 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2306 PF10067.4 EIM83291.1 - 0.4 10.8 0.1 0.4 10.8 0.0 2.4 2 2 2 4 4 4 0 Predicted membrane protein (DUF2306) AAA_10 PF12846.2 EIM83293.1 - 2.2e-09 37.2 0.0 1.7e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EIM83293.1 - 8.4e-06 25.3 0.0 3.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EIM83293.1 - 0.0051 16.9 0.2 5.1 7.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain DEAD PF00270.24 EIM83293.1 - 0.093 12.2 0.0 0.85 9.0 0.0 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase GCIP PF13324.1 EIM83294.1 - 0.036 13.2 3.5 0.98 8.5 0.7 2.2 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF948 PF06103.6 EIM83294.1 - 0.097 12.5 0.3 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EIM83294.1 - 0.2 11.5 3.6 0.14 11.9 0.2 2.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3812 PF12757.2 EIM83294.1 - 0.53 10.2 9.1 0.1 12.5 2.8 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3812) ubiquitin PF00240.18 EIM83295.1 - 7.1e-205 662.8 35.8 1e-33 114.5 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.3 EIM83295.1 - 3.7e-115 375.7 35.3 1.1e-18 66.6 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM83295.1 - 5.5e-35 119.4 17.8 0.00032 20.8 0.1 8.0 6 6 0 6 6 6 6 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIM83295.1 - 1e-30 106.5 3.0 0.0034 17.1 0.0 6.0 6 0 0 6 6 6 6 Telomere stability and silencing DUF2407 PF10302.4 EIM83295.1 - 2.5e-19 69.2 5.8 0.29 11.3 0.0 6.2 1 1 3 6 6 6 6 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIM83295.1 - 3.8e-19 68.5 9.6 0.22 11.4 0.0 7.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EIM83295.1 - 8.9e-16 57.7 0.0 2.6 8.1 0.0 6.8 6 0 0 6 6 6 6 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EIM83295.1 - 7.7e-10 38.3 11.1 5.9 6.7 0.0 6.3 6 0 0 6 6 6 6 FlgD Ig-like domain TUG-UBL1 PF11470.3 EIM83295.1 - 7.5e-08 32.1 11.1 12 5.9 0.0 6.2 6 0 0 6 6 6 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EIM83295.1 - 1.4e-05 25.3 2.3 1.2e+02 3.0 0.0 6.1 6 0 0 6 6 6 0 ACT domain Big_3_3 PF13750.1 EIM83295.1 - 2.9e-05 23.5 0.0 87 2.5 0.0 5.7 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EIM83295.1 - 0.005 15.2 23.6 7 4.8 0.1 7.7 7 5 0 7 7 7 5 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EIM83295.1 - 0.03 14.2 47.6 5.5 7.0 1.2 6.3 6 0 0 6 6 6 0 Tash protein PEST motif GABP-alpha PF11620.3 EIM83295.1 - 0.22 11.5 15.2 99 3.0 0.1 5.8 6 0 0 6 6 6 0 GA-binding protein alpha chain WD40 PF00400.27 EIM83296.1 - 5e-74 241.7 11.8 1.4e-13 50.1 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIM83296.1 - 9.2e-15 54.8 0.0 4.3e-06 26.5 0.0 3.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIM83296.1 - 7.1e-08 31.6 2.5 0.074 11.7 0.2 5.2 1 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EIM83296.1 - 4.8e-06 24.9 5.7 0.16 10.0 0.5 4.6 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EIM83296.1 - 9.9e-05 21.2 0.2 0.0052 15.6 0.0 2.3 2 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 EIM83296.1 - 0.001 18.5 0.4 3.9 6.8 0.0 3.1 2 1 0 2 2 2 2 PQQ-like domain Kelch_6 PF13964.1 EIM83296.1 - 0.0014 18.6 0.2 0.016 15.3 0.0 2.8 4 0 0 4 4 3 1 Kelch motif DUF1513 PF07433.6 EIM83296.1 - 0.002 17.0 0.1 0.31 9.8 0.0 3.1 1 1 0 3 3 3 1 Protein of unknown function (DUF1513) Peptidase_S9_N PF02897.10 EIM83296.1 - 0.0056 15.3 0.0 1.6 7.2 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain IKI3 PF04762.7 EIM83296.1 - 0.0069 14.2 0.6 0.68 7.6 0.0 2.8 2 1 1 3 3 3 1 IKI3 family Cytochrom_D1 PF02239.11 EIM83296.1 - 0.097 10.9 0.3 38 2.4 0.0 3.1 1 1 1 3 3 3 0 Cytochrome D1 heme domain Hira PF07569.6 EIM83296.1 - 0.13 11.4 0.2 18 4.4 0.0 3.4 2 1 2 4 4 4 0 TUP1-like enhancer of split adh_short PF00106.20 EIM83298.1 - 3.8e-32 111.4 0.2 5.1e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM83298.1 - 4.9e-17 62.4 0.1 6.7e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM83298.1 - 1.1e-15 57.7 0.0 1.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIM83298.1 - 0.0011 17.9 0.3 0.0014 17.5 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIM83298.1 - 0.012 15.6 0.2 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIM83298.1 - 0.013 14.8 0.5 0.063 12.7 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIM83298.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RICH PF05062.7 EIM83298.1 - 0.13 12.4 0.3 0.24 11.5 0.1 1.5 2 0 0 2 2 2 0 RICH domain 2OG-FeII_Oxy PF03171.15 EIM83300.1 - 0.00046 20.4 0.0 0.00081 19.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM83300.1 - 0.0028 18.1 0.1 0.0072 16.8 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_S14 PF00253.16 EIM83301.1 - 1.4e-17 62.8 3.4 1.4e-17 62.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Glyco_transf_28 PF03033.15 EIM83302.1 - 1.3e-24 86.5 0.0 2.6e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EIM83302.1 - 1.8e-18 65.8 0.6 1.2e-08 34.3 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 EIM83302.1 - 4.4e-11 42.9 0.1 1.3e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 EIM83302.1 - 1.5e-05 23.7 0.0 3.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 EIM83302.1 - 0.00015 22.0 1.5 0.01 16.0 1.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EIM83302.1 - 0.0074 16.3 0.3 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EIM83302.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain SUR7 PF06687.7 EIM83303.1 - 7.1e-19 68.2 6.4 8.6e-19 67.9 4.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIM83303.1 - 2.2e-05 24.2 3.6 2.2e-05 24.2 2.5 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Acyl-CoA_dh_C PF12806.2 EIM83303.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like PIRT PF15099.1 EIM83303.1 - 1.2 8.3 3.7 0.53 9.5 0.3 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Syndecan PF01034.15 EIM83304.1 - 0.027 14.1 0.4 0.31 10.7 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain DUF2742 PF10888.3 EIM83304.1 - 0.11 12.4 0.2 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) AGTRAP PF06396.6 EIM83305.1 - 0.011 15.3 0.4 0.027 14.1 0.3 1.7 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Mito_fiss_reg PF05308.6 EIM83305.1 - 0.87 8.8 3.1 5.2 6.3 1.9 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator WD40 PF00400.27 EIM83306.1 - 3.4e-09 36.2 12.8 0.00024 20.8 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 EIM83306.1 - 0.042 12.0 0.0 0.064 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Lactamase_B_2 PF12706.2 EIM83308.1 - 9.5e-11 41.5 0.8 1.6e-10 40.8 0.6 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM83308.1 - 1.8e-09 37.5 0.4 3.2e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CAP PF00188.21 EIM83311.1 - 1.5e-22 80.3 1.6 1.9e-22 80.0 1.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PCI_Csn8 PF10075.4 EIM83312.1 - 4.7e-22 78.3 0.0 6.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIM83312.1 - 1.5e-20 73.6 0.1 2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PUF PF00806.14 EIM83313.1 - 2.7e-58 190.2 8.9 9.3e-08 31.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1168 PF06658.7 EIM83313.1 - 0.0073 15.8 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF260 PF03195.9 EIM83313.1 - 0.014 15.6 0.0 0.14 12.4 0.0 2.6 2 2 1 3 3 3 0 Protein of unknown function DUF260 Atg14 PF10186.4 EIM83314.1 - 3.9e-12 45.7 0.0 7.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Vpu PF00558.14 EIM83315.1 - 0.027 13.9 0.3 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 Vpu protein RIC1 PF07064.8 EIM83316.1 - 6.9e-78 261.6 0.4 1e-77 261.0 0.3 1.3 1 0 0 1 1 1 1 RIC1 PRELI PF04707.9 EIM83317.1 - 5.6e-34 116.9 0.0 6.7e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.6 EIM83317.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) ArsA_ATPase PF02374.10 EIM83319.1 - 8.3e-113 376.4 0.9 9.6e-113 376.2 0.6 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EIM83319.1 - 9.2e-17 61.0 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIM83319.1 - 4.9e-09 36.2 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIM83319.1 - 1.3e-05 24.5 0.0 3.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EIM83319.1 - 6e-05 22.5 0.4 0.0011 18.4 0.1 2.4 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EIM83319.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 EIM83319.1 - 0.0015 18.0 0.1 0.0058 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM83319.1 - 0.0017 18.0 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 EIM83319.1 - 0.0047 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein MipZ PF09140.6 EIM83319.1 - 0.0051 15.9 0.1 0.017 14.2 0.0 1.7 1 1 1 2 2 2 1 ATPase MipZ IstB_IS21 PF01695.12 EIM83319.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein VirC1 PF07015.6 EIM83319.1 - 0.045 12.8 0.5 0.11 11.6 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein ResIII PF04851.10 EIM83319.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EIM83319.1 - 0.19 11.9 1.3 3.3 7.9 0.1 3.1 2 2 0 3 3 3 0 RNA helicase Cytochrom_B562 PF07361.6 EIM83319.1 - 0.3 11.5 2.3 25 5.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b562 PAP1 PF08601.5 EIM83320.1 - 2.7e-10 40.4 0.0 2.7e-10 40.4 0.0 4.2 2 1 1 4 4 4 1 Transcription factor PAP1 bZIP_1 PF00170.16 EIM83320.1 - 3.4e-10 39.7 15.2 6.1e-10 38.9 10.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF2216 PF10226.4 EIM83320.1 - 0.00077 19.0 1.2 0.0017 17.9 0.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) bZIP_2 PF07716.10 EIM83320.1 - 0.001 18.8 16.4 0.0039 16.9 11.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.13 EIM83320.1 - 0.031 14.2 3.1 0.12 12.4 2.1 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EIM83320.1 - 0.07 12.6 3.7 0.13 11.7 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 EIM83320.1 - 0.42 10.9 4.9 0.45 10.8 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EIM83320.1 - 3 8.2 13.1 1 9.6 6.8 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor Erf4 PF10256.4 EIM83321.1 - 9.2e-29 99.7 0.1 1.2e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.23 EIM83322.1 - 6.2e-47 155.3 24.2 1.9e-07 30.3 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83322.1 - 7e-45 150.5 15.6 6.5e-10 38.5 0.0 6.5 2 1 4 7 7 7 6 TPR repeat TPR_2 PF07719.12 EIM83322.1 - 7.1e-43 141.0 20.2 7.9e-05 22.2 0.0 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83322.1 - 5.8e-33 110.2 15.9 9e-05 21.9 0.0 10.4 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83322.1 - 3.8e-31 106.8 20.6 5.3e-09 35.8 0.1 7.2 2 1 7 9 9 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83322.1 - 3.9e-28 97.4 6.9 9.1e-05 23.0 0.0 7.1 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83322.1 - 1.3e-24 84.2 16.7 0.00026 20.9 0.3 9.3 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83322.1 - 2.5e-23 82.1 10.3 5.2e-05 23.5 0.1 6.7 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83322.1 - 9.2e-23 78.1 12.4 0.016 14.9 0.0 9.6 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83322.1 - 2.1e-21 74.8 13.6 0.0032 17.8 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM83322.1 - 3e-21 73.9 8.6 0.011 16.3 0.0 9.6 3 2 7 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 EIM83322.1 - 4.9e-14 52.2 6.0 3.7e-06 26.9 0.5 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIM83322.1 - 5.5e-13 48.5 8.0 0.0013 18.5 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIM83322.1 - 1.4e-07 30.8 4.4 0.00041 19.5 1.1 4.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIM83322.1 - 0.00031 20.7 1.0 0.004 17.2 0.0 3.3 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EIM83322.1 - 0.00079 19.3 5.8 1.6 8.6 0.4 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 EIM83322.1 - 0.0014 18.1 0.9 0.37 10.2 0.0 3.1 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 EIM83322.1 - 0.01 14.6 0.1 2.4 6.8 0.0 2.4 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 EIM83322.1 - 0.012 14.8 10.2 3.3 6.7 2.2 4.4 1 1 3 5 5 5 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.1 EIM83322.1 - 0.099 12.5 0.3 46 4.0 0.0 3.8 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.9 EIM83322.1 - 0.18 10.7 2.5 2.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Transcriptional repressor TCF25 TPR_10 PF13374.1 EIM83322.1 - 0.59 10.1 9.3 50 4.0 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat 4F5 PF04419.9 EIM83323.1 - 2e-08 34.8 12.1 2e-08 34.8 8.4 2.2 2 0 0 2 2 2 1 4F5 protein family Mnd1 PF03962.10 EIM83323.1 - 0.81 9.3 5.3 0.9 9.1 3.7 1.0 1 0 0 1 1 1 0 Mnd1 family Pinin_SDK_memA PF04696.8 EIM83323.1 - 0.86 9.2 5.7 1.1 8.9 3.9 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Herpes_UL17 PF04559.7 EIM83323.1 - 6.9 5.1 6.2 7.2 5.0 4.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein Brr6_like_C_C PF10104.4 EIM83324.1 - 1.2e-40 138.1 0.4 1.9e-40 137.5 0.3 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.10 EIM83324.1 - 0.023 14.7 0.0 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 Ctr copper transporter family CLP_protease PF00574.18 EIM83325.1 - 5e-74 247.8 0.0 6.3e-74 247.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease ECH PF00378.15 EIM83325.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Reprolysin_5 PF13688.1 EIM83326.1 - 7.4e-44 150.0 8.1 7.4e-44 150.0 5.6 2.9 2 1 2 4 4 4 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EIM83326.1 - 2.3e-38 131.8 3.5 5.8e-38 130.4 2.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EIM83326.1 - 2e-37 128.9 5.2 2e-37 128.9 3.6 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIM83326.1 - 6.9e-19 68.5 0.1 6.9e-19 68.5 0.1 3.2 3 1 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EIM83326.1 - 1.1e-15 57.5 22.3 1.1e-15 57.5 15.4 4.4 2 1 2 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 EIM83326.1 - 1.7e-07 31.1 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 EIM83326.1 - 5.9e-07 29.2 8.3 4.5e-06 26.4 5.7 2.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease SKG6 PF08693.5 EIM83326.1 - 0.047 13.0 1.5 0.094 12.0 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EIM83326.1 - 0.33 10.5 2.5 0.67 9.5 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EIM83327.1 - 0.0068 14.7 0.2 0.011 14.0 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EIM83327.1 - 0.011 15.4 0.1 0.011 15.4 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 EIM83327.1 - 0.046 14.1 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CBM_6 PF03422.10 EIM83327.1 - 0.079 13.1 4.0 0.7 10.0 0.5 3.2 2 2 0 3 3 3 0 Carbohydrate binding module (family 6) SseC PF04888.7 EIM83327.1 - 0.29 10.4 0.6 0.43 9.8 0.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Chorismate_synt PF01264.16 EIM83329.1 - 1e-128 428.7 0.1 4.2e-128 426.6 0.1 1.7 1 1 0 1 1 1 1 Chorismate synthase Topo_Zn_Ribbon PF08272.6 EIM83329.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like F-box-like PF12937.2 EIM83331.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 1.8 2 0 0 2 2 2 1 F-box-like DUF3760 PF12586.3 EIM83331.1 - 0.0038 17.0 0.1 0.009 15.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) LRR_8 PF13855.1 EIM83332.1 - 0.019 14.7 1.1 0.96 9.2 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EIM83332.1 - 0.034 13.7 1.3 0.27 10.9 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) STAS_2 PF13466.1 EIM83332.1 - 0.095 12.7 0.2 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 STAS domain F-box-like PF12937.2 EIM83333.1 - 1.1e-09 37.8 0.8 3.5e-09 36.2 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM83333.1 - 0.24 11.1 8.7 0.15 11.7 0.7 3.2 4 0 0 4 4 4 0 F-box domain NOA36 PF06524.7 EIM83333.1 - 4.9 6.3 9.1 7.7 5.6 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 EIM83333.1 - 8.8 6.1 13.8 13 5.5 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.8 EIM83333.1 - 9.2 4.8 13.5 13 4.3 9.4 1.1 1 0 0 1 1 1 0 Paf1 p450 PF00067.17 EIM83334.1 - 1.3e-48 165.6 0.0 1.7e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UTP15_C PF09384.5 EIM83334.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal DUF3175 PF11373.3 EIM83334.1 - 0.11 12.4 0.1 6.1 6.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) Flavin_Reduct PF01613.13 EIM83335.1 - 3e-15 56.3 0.0 3.9e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EIM83335.1 - 1.2e-06 28.2 0.1 1.8e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 EIM83335.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TPR_12 PF13424.1 EIM83336.1 - 7.3e-150 487.2 38.4 9.6e-20 70.3 0.2 8.2 2 1 9 11 11 11 10 Tetratricopeptide repeat TPR_10 PF13374.1 EIM83336.1 - 7.4e-148 476.9 33.8 1.6e-14 53.2 0.1 12.4 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83336.1 - 8.5e-33 109.8 5.3 0.13 12.4 0.0 11.3 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83336.1 - 2.7e-31 104.8 26.2 0.012 15.3 0.0 11.8 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_4 PF07721.9 EIM83336.1 - 9.7e-29 96.8 21.6 0.031 14.6 0.2 10.9 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83336.1 - 4.5e-27 91.7 6.4 0.18 11.8 0.0 11.4 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83336.1 - 7.1e-25 87.0 10.0 7.3e-05 23.3 0.2 8.1 2 1 3 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83336.1 - 6.2e-21 73.0 4.0 0.7 9.6 0.0 11.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83336.1 - 1.2e-16 60.0 8.2 0.0061 16.1 0.0 7.0 4 1 4 8 8 8 7 TPR repeat Rab5-bind PF09311.6 EIM83336.1 - 1.2e-15 57.8 20.2 0.25 11.2 0.1 9.6 1 1 8 9 9 9 6 Rabaptin-like protein TPR_8 PF13181.1 EIM83336.1 - 1.5e-14 52.5 1.7 4.6 7.2 0.0 10.4 11 0 0 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EIM83336.1 - 1.3e-12 47.6 0.2 0.69 10.0 0.0 7.1 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIM83336.1 - 1.1e-10 41.1 22.9 8.4 7.3 0.0 11.2 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83336.1 - 1.3e-10 41.4 6.7 1.6 9.1 0.1 8.3 3 2 8 11 11 10 3 Tetratricopeptide repeat TPR_3 PF07720.7 EIM83336.1 - 3.7e-09 36.1 0.0 0.36 10.6 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF832 PF05734.6 EIM83336.1 - 1e-07 31.4 0.1 0.22 10.7 0.0 5.3 1 1 5 6 6 6 1 Herpesvirus protein of unknown function (DUF832) TPR_6 PF13174.1 EIM83336.1 - 7e-06 26.1 21.1 6.8 7.3 0.0 10.3 11 0 0 11 11 10 0 Tetratricopeptide repeat PPR PF01535.15 EIM83336.1 - 0.00072 19.3 2.8 76 3.6 0.0 6.8 9 0 0 9 9 6 0 PPR repeat YojJ PF10372.4 EIM83336.1 - 0.003 17.4 3.0 87 3.0 0.0 7.0 8 0 0 8 8 8 0 Bacterial membrane-spanning protein N-terminus Rabaptin PF03528.10 EIM83336.1 - 0.03 14.2 14.4 1.9 8.4 0.1 5.6 2 2 2 5 5 5 0 Rabaptin TPR_9 PF13371.1 EIM83336.1 - 0.2 11.4 5.8 1.8 8.4 0.1 4.5 3 2 1 5 5 4 0 Tetratricopeptide repeat DUF2508 PF10704.4 EIM83336.1 - 0.47 10.6 9.1 5.3 7.2 0.0 5.7 8 0 0 8 8 4 0 Protein of unknown function (DUF2508) DUF1543 PF07566.7 EIM83336.1 - 0.65 9.5 10.9 12 5.4 0.0 6.3 7 0 0 7 7 7 0 Domain of Unknown Function (DUF1543) DNA_gyraseB_C PF00986.16 EIM83336.1 - 1.5 8.6 15.4 16 5.3 0.0 6.8 9 0 0 9 9 8 0 DNA gyrase B subunit, carboxyl terminus WAC_Acf1_DNA_bd PF10537.4 EIM83337.1 - 1.5e-35 121.3 1.3 4.4e-35 119.9 0.9 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EIM83337.1 - 2.8e-12 46.2 0.1 2.9e-11 42.9 0.1 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.1 EIM83337.1 - 9.2e-06 25.3 0.0 2.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 EIM83337.1 - 0.00026 20.7 0.2 0.00078 19.1 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM2 PF15613.1 EIM83337.1 - 0.0011 18.7 0.1 0.0011 18.7 0.1 2.9 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 2 Transglut_i_TM PF14400.1 EIM83337.1 - 0.047 13.1 2.6 0.13 11.7 0.0 2.7 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices Fungal_trans PF04082.13 EIM83338.1 - 2.4e-12 46.2 0.1 6.5e-12 44.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM83338.1 - 0.0066 16.3 10.5 0.011 15.5 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 EIM83339.1 - 2.1e-56 191.1 23.0 2.7e-56 190.8 16.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM51 PF15345.1 EIM83339.1 - 0.21 11.2 0.9 2 8.0 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Trp_Tyr_perm PF03222.8 EIM83339.1 - 0.69 8.6 22.9 0.0074 15.1 10.1 1.9 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family TPR_10 PF13374.1 EIM83340.1 - 6.5e-29 98.9 22.2 1.4e-07 31.1 0.2 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83340.1 - 4.1e-27 93.9 26.4 1.3e-09 37.8 1.9 5.2 2 2 2 5 5 5 5 Tetratricopeptide repeat Patatin PF01734.17 EIM83340.1 - 1.6e-17 64.1 0.1 9.2e-17 61.6 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_16 PF13432.1 EIM83340.1 - 9.7e-12 45.2 13.6 1e-06 29.2 0.4 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83340.1 - 1.3e-10 41.4 6.3 1.5e-05 25.1 0.5 4.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83340.1 - 8.7e-09 34.6 19.0 0.1 12.5 0.3 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83340.1 - 5.3e-08 32.3 6.8 0.025 14.1 0.1 3.8 3 0 0 3 3 3 3 TPR repeat Apc3 PF12895.2 EIM83340.1 - 1.1e-07 31.8 2.9 0.0014 18.7 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIM83340.1 - 4.5e-06 26.8 17.9 1.5 9.7 0.2 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83340.1 - 5e-06 25.8 12.7 0.87 9.3 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83340.1 - 2e-05 24.0 1.4 6.8 6.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIM83340.1 - 0.00015 21.8 2.5 7.3 6.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIM83340.1 - 0.00024 21.2 15.4 1.3 9.7 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83340.1 - 0.0021 18.4 14.9 6.3 7.4 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83340.1 - 0.036 13.8 13.2 2.9 7.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83340.1 - 5.8 7.3 8.8 1.4e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat NICE-3 PF07406.6 EIM83341.1 - 0.0037 16.7 0.3 0.0076 15.7 0.1 1.5 1 1 0 1 1 1 1 NICE-3 protein Cortexin PF11057.3 EIM83341.1 - 0.014 14.9 0.4 0.014 14.9 0.3 2.0 1 1 1 2 2 2 0 Cortexin of kidney DUF2838 PF10998.3 EIM83341.1 - 0.021 14.7 0.3 0.036 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) GST_N_3 PF13417.1 EIM83342.1 - 9.1e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM83342.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM83342.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain FAD_binding_6 PF00970.19 EIM83343.1 - 7.4e-32 109.4 0.0 1.2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIM83343.1 - 1e-28 100.0 0.0 1.6e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIM83343.1 - 1.9e-06 27.8 0.0 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIM83343.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DSPc PF00782.15 EIM83344.1 - 4e-20 71.7 0.0 4.7e-19 68.2 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM83344.1 - 0.0087 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF846 PF05832.7 EIM83345.1 - 5.1e-53 178.6 9.4 6.2e-53 178.3 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DEAD PF00270.24 EIM83347.1 - 1.1e-19 70.6 0.0 6.7e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM83347.1 - 4.8e-17 61.5 0.2 2.3e-16 59.3 0.1 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM83347.1 - 5.4e-17 62.2 0.4 1.8e-16 60.4 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AA_permease PF00324.16 EIM83348.1 - 7.5e-126 420.2 35.6 9.2e-126 419.9 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM83348.1 - 8.8e-38 129.9 44.7 1.1e-37 129.6 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EIM83348.1 - 0.2 10.0 0.3 0.3 9.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) AA_permease PF00324.16 EIM83349.1 - 7.6e-131 436.7 35.5 8.5e-131 436.5 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM83349.1 - 4.7e-37 127.5 42.8 5.7e-37 127.2 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease LRR_8 PF13855.1 EIM83352.1 - 1.2e-10 40.9 4.1 0.0047 16.6 0.1 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EIM83352.1 - 3.2e-08 33.0 13.8 0.0036 16.8 0.0 6.5 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM83352.1 - 5.8e-08 32.0 7.7 3 8.1 0.0 7.3 7 1 0 7 7 7 4 Leucine Rich repeat LRR_7 PF13504.1 EIM83352.1 - 2.6 8.6 11.7 47 4.8 0.0 6.7 8 0 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 EIM83352.1 - 4.3 7.7 12.1 59 4.2 0.0 6.8 8 1 0 8 8 8 0 Leucine Rich Repeat RhoGEF PF00621.15 EIM83353.1 - 9.2e-46 155.9 0.0 1.4e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EIM83353.1 - 1.6e-10 40.3 2.4 0.00024 20.6 0.0 3.0 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM83353.1 - 2.9e-08 33.3 3.0 8.1e-05 22.2 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIM83353.1 - 0.0011 18.6 2.9 15 6.0 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EIM83353.1 - 0.0087 16.0 1.8 67 4.3 0.0 4.6 5 0 0 5 5 5 0 Leucine rich repeat PAXNEB PF05625.6 EIM83354.1 - 2.3e-48 164.9 0.0 4.7e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 PAXNEB protein APG5 PF04106.7 EIM83354.1 - 0.057 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 TPR_11 PF13414.1 EIM83355.1 - 2.2e-11 43.1 3.4 2.7e-05 23.7 0.8 2.9 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIM83355.1 - 7.9e-07 28.4 1.2 0.023 14.2 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83355.1 - 1.2e-06 27.9 3.3 0.12 12.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83355.1 - 0.00047 20.7 4.0 0.93 10.2 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83355.1 - 0.045 13.5 0.0 8 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83355.1 - 0.087 12.7 1.8 7.4 6.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GRA6 PF05084.8 EIM83355.1 - 0.23 10.9 5.1 0.42 10.1 3.5 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TPR_14 PF13428.1 EIM83355.1 - 0.26 12.0 2.0 5.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FtsZ_C PF12327.3 EIM83355.1 - 0.62 10.1 2.6 2 8.5 0.2 2.2 1 1 1 2 2 2 0 FtsZ family, C-terminal domain Paf1 PF03985.8 EIM83355.1 - 0.99 8.0 5.8 1.9 7.1 4.0 1.4 1 0 0 1 1 1 0 Paf1 Peptidase_S24 PF00717.18 EIM83356.1 - 4.8e-07 29.3 0.0 8.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EIM83356.1 - 5.5e-06 25.9 0.0 0.001 18.5 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 adh_short PF00106.20 EIM83357.1 - 8.2e-16 58.3 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM83357.1 - 2.6e-08 33.7 0.0 6.1e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIM83357.1 - 9.6e-05 22.2 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM83357.1 - 0.004 16.6 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIM83357.1 - 0.01 14.8 0.2 0.015 14.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EIM83357.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EIM83357.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_N PF05222.10 EIM83358.1 - 1.4e-27 96.3 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIM83358.1 - 1e-14 54.4 0.0 1.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SH3_1 PF00018.23 EIM83361.1 - 0.00079 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM83361.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM83361.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain zf-Tim10_DDP PF02953.10 EIM83362.1 - 5.8e-21 73.5 1.7 7.4e-21 73.2 1.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EIM83362.1 - 0.047 13.1 1.2 0.073 12.5 0.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Acyltransferase PF01553.16 EIM83363.1 - 6.2e-22 77.4 0.0 9.6e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Peroxidase_2 PF01328.12 EIM83365.1 - 1e-24 86.8 0.0 1.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 TPR_10 PF13374.1 EIM83366.1 - 2e-38 129.2 24.9 4.8e-08 32.6 0.1 7.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83366.1 - 9e-31 105.6 22.4 1.3e-09 37.8 0.1 5.1 2 1 2 5 5 5 5 Tetratricopeptide repeat Apc3 PF12895.2 EIM83366.1 - 1.7e-12 47.3 10.1 0.0004 20.4 0.1 4.1 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM83366.1 - 7e-10 37.9 10.3 0.27 11.1 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83366.1 - 3.4e-09 36.8 4.9 0.051 13.9 0.0 4.8 3 3 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM83366.1 - 1.4e-08 33.9 7.6 0.2 11.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM83366.1 - 5.5e-08 32.7 9.8 0.87 10.3 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIM83366.1 - 5.6e-08 32.4 10.7 0.12 12.8 0.6 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83366.1 - 1.3e-07 30.8 1.3 4.4 7.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83366.1 - 3.3e-07 30.3 3.2 0.87 10.1 0.0 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83366.1 - 6e-06 26.7 14.9 0.00049 20.7 0.1 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83366.1 - 3e-05 23.4 2.3 0.67 9.6 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83366.1 - 9e-05 22.0 4.5 0.22 11.2 0.0 5.2 5 2 0 5 5 5 1 TPR repeat TPR_17 PF13431.1 EIM83366.1 - 0.0044 17.1 5.4 42 4.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM83366.1 - 0.57 10.0 4.1 6.8 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIM83366.1 - 1.3 9.1 7.6 3.4 7.8 0.2 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EIM83367.1 - 1.9e-19 69.7 0.0 2.1e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM83367.1 - 1.9e-16 60.0 0.0 2.1e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM83367.1 - 0.013 14.8 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EIM83367.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 EIM83368.1 - 1.5e-14 54.4 1.4 4.1e-11 43.1 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM83368.1 - 0.0016 18.0 0.0 0.0043 16.6 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIM83368.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Ndr PF03096.9 EIM83368.1 - 0.28 9.6 0.0 0.43 9.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Aconitase PF00330.15 EIM83371.1 - 4.4e-154 513.3 0.0 3.8e-153 510.3 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIM83371.1 - 2.1e-35 121.7 0.0 4.1e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MutS_V PF00488.16 EIM83372.1 - 6.1e-80 268.0 0.0 1.1e-79 267.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIM83372.1 - 1e-42 146.2 3.8 2.5e-42 144.9 2.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIM83372.1 - 2.8e-22 78.8 0.0 9.8e-22 77.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EIM83372.1 - 1.1e-12 48.2 0.0 2.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EIM83372.1 - 0.00035 20.0 0.0 0.00083 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EIM83372.1 - 0.00063 20.1 0.2 0.0083 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MutS_IV PF05190.13 EIM83372.1 - 0.0039 17.3 0.2 0.0086 16.2 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EIM83372.1 - 0.048 13.5 0.0 0.2 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM83372.1 - 0.23 11.5 2.0 15 5.7 0.0 3.2 3 2 0 3 3 3 0 AAA domain Septin PF00735.13 EIM83373.1 - 4.2e-109 363.9 0.4 5.9e-109 363.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIM83373.1 - 4.1e-05 23.4 0.0 0.00013 21.9 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM83373.1 - 0.003 17.4 3.1 0.78 9.5 0.0 3.0 2 1 0 3 3 3 2 Dynamin family AAA_17 PF13207.1 EIM83373.1 - 0.0033 18.2 0.9 0.05 14.4 0.0 2.5 1 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EIM83373.1 - 0.0046 16.1 0.0 0.0084 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EIM83373.1 - 0.0047 16.1 0.2 0.02 14.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIM83373.1 - 0.0049 16.3 0.0 0.068 12.5 0.0 2.4 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM83373.1 - 0.016 15.7 0.3 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EIM83373.1 - 0.021 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3543 PF12063.3 EIM83374.1 - 0.04 13.1 0.1 0.093 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Glyco_hydro_3 PF00933.16 EIM83376.1 - 8.5e-74 248.2 0.0 1.2e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM83376.1 - 5.1e-51 173.3 0.6 1.4e-50 171.9 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM83376.1 - 9.1e-20 70.3 0.0 1.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EIM83377.1 - 5.6e-84 281.6 0.1 8.2e-84 281.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM83377.1 - 4.6e-59 199.6 2.5 1.7e-58 197.8 0.6 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM83377.1 - 3.8e-19 68.4 0.0 6.8e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 EIM83377.1 - 6e-11 41.7 10.4 6e-11 41.7 7.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DMAP_binding PF06464.6 EIM83377.1 - 0.14 12.7 0.7 17 6.0 0.1 2.6 3 0 0 3 3 3 0 DMAP1-binding Domain Oxysterol_BP PF01237.13 EIM83378.1 - 1.4e-96 323.0 4.0 4e-96 321.6 2.8 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EIM83378.1 - 4.1e-16 58.8 1.8 9.7e-16 57.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EIM83378.1 - 0.00017 21.7 0.6 0.0047 17.1 0.1 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIM83378.1 - 0.0012 19.0 0.6 0.0033 17.5 0.0 2.1 2 1 0 2 2 2 1 PH domain 6PGD PF00393.14 EIM83379.1 - 8.5e-133 442.0 0.0 1.1e-132 441.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIM83379.1 - 6.7e-51 172.3 0.0 9.7e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIM83379.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EIM83379.1 - 0.014 15.4 0.1 0.075 13.1 0.1 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EIM83379.1 - 0.03 14.7 0.1 0.062 13.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Asn_synthase PF00733.16 EIM83380.1 - 5.2e-48 163.7 0.0 7.9e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIM83380.1 - 1.2e-06 28.2 0.0 3.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIM83380.1 - 0.028 14.3 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain QueC PF06508.8 EIM83380.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.20 EIM83381.1 - 1.4e-23 83.7 4.1 1.9e-23 83.3 2.3 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family MgtE_N PF03448.12 EIM83381.1 - 0.039 14.2 3.3 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain Big_3 PF07523.7 EIM83381.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) RRM_1 PF00076.17 EIM83382.1 - 1.4e-53 178.3 0.0 5.9e-19 67.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM83382.1 - 4.5e-39 132.2 0.0 1.6e-12 47.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM83382.1 - 2.8e-26 91.1 0.0 9.9e-09 34.9 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM83382.1 - 4.7e-05 23.0 0.0 0.32 10.7 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EIM83382.1 - 0.0016 18.3 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) GST_N_3 PF13417.1 EIM83383.1 - 6.1e-19 68.0 0.0 9.8e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM83383.1 - 7.8e-15 54.8 0.0 1.7e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM83383.1 - 2.5e-13 49.8 0.0 3.7e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM83383.1 - 2e-12 46.9 0.0 3.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM83383.1 - 4.5e-09 36.0 0.0 6.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM83383.1 - 0.00034 21.0 0.0 0.00044 20.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.17 EIM83384.1 - 6.3e-58 194.7 0.2 7.4e-58 194.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM83384.1 - 8.3e-19 68.2 0.0 1.8e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM83384.1 - 3.3e-14 52.5 0.0 4.1e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM83384.1 - 3.7e-08 32.8 0.1 4.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM83384.1 - 7.4e-08 32.0 0.0 1.5e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM83384.1 - 3.7e-07 30.1 0.0 5e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EIM83384.1 - 0.00023 20.7 0.5 0.016 14.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIM83384.1 - 0.00036 20.0 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EIM83384.1 - 0.00038 20.6 0.0 0.00073 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EIM83384.1 - 0.00099 18.2 0.2 0.036 13.0 0.0 2.3 2 1 0 2 2 2 1 Septin DUF258 PF03193.11 EIM83384.1 - 0.0013 17.9 0.1 0.0026 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EIM83384.1 - 0.0026 17.2 0.0 0.011 15.1 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EIM83384.1 - 0.0053 16.3 0.2 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM83384.1 - 0.0057 16.3 0.1 0.041 13.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EIM83384.1 - 0.0057 15.8 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EIM83384.1 - 0.006 16.3 0.3 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase NTPase_1 PF03266.10 EIM83384.1 - 0.0061 16.2 0.1 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 NTPase MobB PF03205.9 EIM83384.1 - 0.0082 15.8 0.1 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIM83384.1 - 0.014 14.8 0.1 0.027 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EIM83384.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIM83384.1 - 0.048 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EIM83384.1 - 0.076 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EIM83384.1 - 0.082 12.1 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EIM83384.1 - 0.23 11.7 1.1 0.45 10.8 0.8 1.8 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.6 EIM83385.1 - 1.6e-43 148.8 21.4 1.6e-43 148.8 14.9 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) KorB PF08535.5 EIM83385.1 - 0.012 15.6 1.9 0.2 11.8 0.1 2.6 1 1 0 2 2 2 0 KorB domain Spc7 PF08317.6 EIM83385.1 - 0.084 11.5 8.9 0.16 10.6 6.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 EIM83385.1 - 0.41 11.0 16.2 0.36 11.1 2.5 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 EIM83385.1 - 0.42 9.7 19.0 0.12 11.5 8.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EIM83385.1 - 0.73 9.6 5.6 1.3 8.8 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 EIM83385.1 - 0.79 10.0 10.7 5.4 7.4 2.1 2.5 1 1 1 2 2 2 0 Snapin/Pallidin TMF_TATA_bd PF12325.3 EIM83385.1 - 1.5 8.5 22.3 0.2 11.3 5.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIM83385.1 - 1.5 8.3 19.5 14 5.2 11.4 2.3 1 1 1 2 2 2 0 IncA protein CENP-H PF05837.7 EIM83385.1 - 2.8 8.1 15.9 2.2 8.4 1.9 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF4094 PF13334.1 EIM83385.1 - 3.4 8.1 8.5 23 5.4 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) YlqD PF11068.3 EIM83385.1 - 4.1 7.4 12.8 0.36 10.8 0.5 3.0 1 1 1 2 2 2 0 YlqD protein Fzo_mitofusin PF04799.8 EIM83385.1 - 5.6 6.3 9.1 0.75 9.1 1.5 2.6 2 1 1 3 3 3 0 fzo-like conserved region Aminotran_4 PF01063.14 EIM83386.1 - 2.8e-23 82.6 0.0 4.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Zn_clus PF00172.13 EIM83387.1 - 2e-14 53.1 32.7 2e-07 30.7 8.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PgaD PF13994.1 EIM83389.1 - 0.17 11.3 0.1 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein PXA PF02194.10 EIM83390.1 - 6e-28 97.6 0.0 1.1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EIM83390.1 - 0.0041 17.1 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal Glyco_hydro_15 PF00723.16 EIM83391.1 - 6.8e-51 173.2 0.0 9.2e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Mpv17_PMP22 PF04117.7 EIM83393.1 - 1.4e-23 82.3 0.1 2.2e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Asp PF00026.18 EIM83394.1 - 5.6e-67 226.2 1.1 6.7e-67 225.9 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM83394.1 - 1.4e-07 31.5 4.6 6e-07 29.5 1.7 2.8 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM83394.1 - 0.0041 17.5 1.0 0.18 12.3 0.1 2.6 2 1 0 2 2 2 1 Aspartyl protease Amidohydro_1 PF01979.15 EIM83395.1 - 2.5e-26 93.1 0.2 2e-25 90.1 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIM83395.1 - 4.5e-15 56.4 0.0 1.2e-13 51.7 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIM83395.1 - 1.6e-14 53.4 0.1 1.2e-13 50.5 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM83395.1 - 1.3e-07 31.1 2.5 1.7e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase family PTE PF02126.13 EIM83395.1 - 0.09 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family BTB PF00651.26 EIM83396.1 - 0.0098 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fcf1 PF04900.7 EIM83399.1 - 2.6e-29 101.2 0.1 4.6e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Fcf1 CENP-U PF13097.1 EIM83399.1 - 6.5 6.6 7.9 21 5.0 0.0 2.7 3 0 0 3 3 3 0 CENP-A nucleosome associated complex (NAC) subunit DUF3695 PF12494.3 EIM83400.1 - 0.14 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) Pro_CA PF00484.14 EIM83401.1 - 2.7e-27 95.6 0.1 3.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Glucosaminidase PF01832.15 EIM83401.1 - 0.059 13.4 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase ThiI PF02568.9 EIM83401.1 - 0.097 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NT5C PF06941.7 EIM83402.1 - 1.9e-13 50.3 0.0 4.4e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 EIM83402.1 - 0.0024 18.1 0.1 0.0084 16.3 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase LNS2 PF08235.8 EIM83402.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) ABC_membrane_2 PF06472.10 EIM83403.1 - 2.4e-86 289.3 1.1 3.1e-86 288.9 0.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIM83403.1 - 6.5e-17 62.1 0.0 1.5e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM83403.1 - 0.00025 21.1 0.1 0.00069 19.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIM83403.1 - 0.014 15.7 0.1 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIM83403.1 - 0.025 14.0 0.0 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EIM83403.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIM83403.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EIM83403.1 - 0.22 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S8 PF00410.14 EIM83404.1 - 1.2e-15 57.4 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 PRELI PF04707.9 EIM83405.1 - 3e-36 124.3 0.0 3.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family B-block_TFIIIC PF04182.7 EIM83406.1 - 5.2e-13 48.6 0.5 4.7e-09 35.9 0.1 3.5 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EIM83406.1 - 0.00045 19.8 3.7 0.81 9.4 0.0 4.7 5 0 0 5 5 5 2 MarR family HTH_24 PF13412.1 EIM83406.1 - 0.0012 18.1 0.2 0.2 11.0 0.0 3.4 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 EIM83406.1 - 0.029 14.6 0.2 3 8.2 0.0 4.2 5 1 0 5 5 5 0 Winged helix DNA-binding domain AT_hook PF02178.14 EIM83406.1 - 1.1 9.0 59.3 0.43 10.3 1.7 6.3 5 0 0 5 5 5 0 AT hook motif Lactamase_B PF00753.22 EIM83407.1 - 1.1e-11 44.7 0.7 2e-11 43.8 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM83407.1 - 5.8e-09 35.7 0.2 7.3e-08 32.1 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GYD PF08734.6 EIM83407.1 - 0.16 11.7 0.1 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 GYD domain EssA PF10661.4 EIM83407.1 - 0.37 10.4 2.8 0.59 9.8 2.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF1162 PF06650.7 EIM83408.1 - 2e-62 210.9 0.0 2e-57 194.5 0.0 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIM83408.1 - 5.4e-30 103.3 0.1 1.7e-29 101.7 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EIM83408.1 - 2.3e-07 30.8 0.0 8.8e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain TSP_1 PF00090.14 EIM83409.1 - 0.12 12.5 1.0 0.26 11.4 0.7 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain ELO PF01151.13 EIM83410.1 - 1.9e-59 200.9 20.9 2.3e-59 200.7 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1049 PF06305.6 EIM83410.1 - 0.014 14.8 0.7 4.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RasGAP PF00616.14 EIM83411.1 - 1.2e-34 119.6 0.0 1.9e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EIM83411.1 - 8.5e-06 25.5 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Adaptin_N PF01602.15 EIM83412.1 - 8e-123 410.5 5.1 1.1e-122 410.0 3.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EIM83412.1 - 1.3e-39 134.6 0.0 5.9e-39 132.5 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EIM83412.1 - 6.7e-18 65.0 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EIM83412.1 - 0.13 12.3 0.8 21 5.5 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat HA2 PF04408.18 EIM83413.1 - 6.1e-17 61.5 0.0 1.4e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 EIM83413.1 - 2.7e-12 47.0 0.0 2.1e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 EIM83413.1 - 4.5e-12 45.6 0.0 1.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM83413.1 - 1.7e-07 30.9 0.1 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EIM83413.1 - 0.00026 20.8 0.1 0.0019 17.9 0.0 2.4 2 1 1 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.1 EIM83413.1 - 0.0075 16.0 0.1 0.031 14.0 0.1 2.1 1 1 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EIM83413.1 - 0.019 14.3 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EIM83413.1 - 0.068 13.0 0.0 0.46 10.2 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM83413.1 - 0.086 12.9 0.2 0.49 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Astro_capsid PF03115.9 EIM83414.1 - 0.00079 17.8 4.8 0.0011 17.3 3.3 1.1 1 0 0 1 1 1 1 Astrovirus capsid protein precursor PPP4R2 PF09184.6 EIM83414.1 - 0.025 14.1 19.9 0.045 13.3 13.8 1.4 1 0 0 1 1 1 0 PPP4R2 ELH PF02323.10 EIM83414.1 - 0.097 11.8 8.9 0.17 11.0 6.2 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor CDC45 PF02724.9 EIM83414.1 - 0.37 8.7 13.6 0.55 8.2 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 EIM83414.1 - 0.38 10.6 16.8 0.62 9.9 11.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.11 EIM83414.1 - 0.76 8.7 8.8 1.2 8.0 6.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MSP1_C PF07462.6 EIM83414.1 - 0.87 7.8 13.8 1.3 7.3 9.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NOA36 PF06524.7 EIM83414.1 - 4.1 6.5 14.3 6 6.0 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 EIM83414.1 - 4.6 6.0 8.5 6.6 5.5 5.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HSP20 PF00011.16 EIM83416.1 - 7.8e-05 22.4 0.0 9.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 EIM83416.1 - 0.042 13.4 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 GvpH SBDS_C PF09377.5 EIM83417.1 - 6.8e-38 129.1 0.0 1.3e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EIM83417.1 - 4.2e-32 109.7 1.7 6.6e-32 109.1 1.2 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BAR PF03114.13 EIM83418.1 - 7.6e-41 140.1 1.0 1e-40 139.7 0.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EIM83418.1 - 1.9e-15 55.9 0.1 3e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM83418.1 - 1e-14 53.8 0.2 1.7e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM83418.1 - 1e-10 40.9 0.0 1.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_9 PF08003.6 EIM83418.1 - 0.0086 14.8 0.5 0.014 14.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF605 PF04652.11 EIM83418.1 - 0.012 14.9 9.2 0.015 14.7 6.4 1.2 1 0 0 1 1 1 0 Vta1 like Vps5 PF09325.5 EIM83418.1 - 0.099 11.8 5.4 1.1 8.4 3.7 2.3 1 1 0 1 1 1 0 Vps5 C terminal like FAP PF07174.6 EIM83418.1 - 4.2 6.5 26.0 7.4 5.7 18.1 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SNF2_N PF00176.18 EIM83419.1 - 2.3e-81 272.8 0.1 2.3e-81 272.8 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EIM83419.1 - 1.1e-20 73.3 0.2 3.4e-20 71.7 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EIM83419.1 - 1.7e-16 59.8 0.0 1.3e-15 56.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIM83419.1 - 2.6e-14 53.1 2.3 2.6e-14 53.1 1.6 3.9 3 2 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EIM83419.1 - 1.3e-13 50.4 9.5 1.3e-13 50.4 6.6 2.7 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EIM83419.1 - 9.8e-10 37.6 1.0 3e-09 36.1 0.7 1.9 1 0 0 1 1 1 1 QLQ DUF2706 PF10913.3 EIM83420.1 - 0.31 10.6 1.9 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) TPR_10 PF13374.1 EIM83421.1 - 3.8e-122 395.2 80.0 5.9e-11 41.9 0.1 15.2 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83421.1 - 3.6e-112 366.4 71.8 1.1e-16 60.4 0.3 9.6 1 1 6 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.23 EIM83421.1 - 2.4e-34 115.5 23.7 0.0031 17.0 0.0 14.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_7 PF13176.1 EIM83421.1 - 1e-31 106.1 42.3 0.00069 19.2 0.1 14.4 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83421.1 - 4.1e-28 97.4 38.7 0.00017 22.1 0.1 9.7 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIM83421.1 - 3e-27 94.0 19.3 5.5e-05 22.7 0.0 10.1 7 3 2 10 10 10 5 TPR repeat TPR_2 PF07719.12 EIM83421.1 - 6.3e-25 85.0 43.0 0.008 16.0 0.0 14.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83421.1 - 9.8e-21 73.8 23.7 0.0011 19.2 0.0 9.8 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_4 PF07721.9 EIM83421.1 - 6.2e-19 66.4 45.3 0.054 13.9 0.0 15.2 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM83421.1 - 2.4e-15 55.6 51.4 0.6 10.8 0.1 14.7 7 5 8 15 15 15 4 Tetratricopeptide repeat Apc3 PF12895.2 EIM83421.1 - 6.8e-14 51.7 17.7 0.013 15.5 0.2 7.2 2 2 7 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EIM83421.1 - 3.7e-13 48.9 17.5 0.29 10.9 0.1 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIM83421.1 - 2.2e-09 36.4 7.0 0.52 10.2 0.0 10.3 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM83421.1 - 2.6e-08 33.8 29.2 2.7 8.6 0.0 12.8 14 1 0 14 14 13 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM83421.1 - 6.1e-06 26.0 11.9 0.74 10.1 0.0 8.5 11 0 0 11 11 7 2 Tetratricopeptide repeat DUF4322 PF14210.1 EIM83421.1 - 1.1e-05 24.8 0.0 0.82 9.1 0.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4322) Fis1_TPR_C PF14853.1 EIM83421.1 - 0.00011 22.0 10.3 1.1 9.1 0.0 6.3 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Ribosomal_L6 PF00347.18 EIM83421.1 - 0.00024 21.5 0.0 43 4.7 0.0 7.1 10 0 0 10 10 6 0 Ribosomal protein L6 TPR_20 PF14561.1 EIM83421.1 - 0.0011 18.9 29.4 1.5 9.0 0.1 10.9 1 1 11 12 12 12 1 Tetratricopeptide repeat DUF1925 PF09094.6 EIM83421.1 - 0.0013 18.7 7.2 12 5.9 0.0 6.7 6 2 2 8 8 6 0 Domain of unknown function (DUF1925) PPR PF01535.15 EIM83421.1 - 0.0024 17.7 16.9 10 6.3 0.0 10.3 13 0 0 13 13 12 0 PPR repeat DUF3856 PF12968.2 EIM83421.1 - 0.0029 17.4 6.0 23 4.8 0.0 6.3 6 2 1 7 7 5 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 EIM83421.1 - 0.0033 17.4 24.6 0.05 13.6 0.5 7.5 6 4 1 7 7 7 1 Tetratrico peptide repeat Coatomer_E PF04733.9 EIM83421.1 - 0.004 16.3 11.7 5.1 6.2 0.0 7.1 3 3 4 8 8 8 1 Coatomer epsilon subunit LAGLIDADG_2 PF03161.8 EIM83421.1 - 0.025 14.5 0.0 3.5 7.5 0.0 3.5 4 0 0 4 4 2 0 LAGLIDADG DNA endonuclease family Ribosomal_S21e PF01249.13 EIM83421.1 - 0.097 12.6 0.2 1.4e+02 2.5 0.0 4.6 3 1 2 5 5 5 0 Ribosomal protein S21e PPR_1 PF12854.2 EIM83421.1 - 0.32 10.5 9.5 43 3.7 0.0 6.8 9 0 0 9 9 8 0 PPR repeat Osmo_CC PF08946.5 EIM83421.1 - 0.45 10.5 13.6 51 4.0 0.0 8.3 9 1 0 9 9 7 0 Osmosensory transporter coiled coil MIT PF04212.13 EIM83421.1 - 0.6 10.0 12.8 17 5.3 0.0 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Es2 PF09751.4 EIM83422.1 - 2.8e-80 270.7 0.0 3.6e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.4 EIM83423.1 - 6.1e-20 71.2 12.8 6.1e-20 71.2 8.9 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 EamA PF00892.15 EIM83425.1 - 1.3e-06 28.4 3.6 1.3e-06 28.4 2.5 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIM83425.1 - 2.3e-06 27.7 2.9 2.3e-06 27.7 2.0 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EIM83425.1 - 0.00048 19.1 0.3 0.00048 19.1 0.2 2.6 3 0 0 3 3 3 1 UAA transporter family DUF914 PF06027.7 EIM83425.1 - 0.0088 14.9 7.3 0.42 9.4 0.0 3.5 4 0 0 4 4 4 2 Eukaryotic protein of unknown function (DUF914) DUF1212 PF06738.7 EIM83425.1 - 0.022 14.2 0.4 0.022 14.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) GFO_IDH_MocA PF01408.17 EIM83426.1 - 1.5e-15 57.7 0.0 2.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM83426.1 - 0.00021 21.6 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DDE_1 PF03184.14 EIM83427.1 - 9.5e-19 67.4 0.0 1.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 EIM83428.1 - 3e-06 26.5 0.0 4.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM83428.1 - 5.2e-06 26.3 0.5 1.1e-05 25.3 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM83428.1 - 4.4e-05 22.9 0.4 0.00011 21.5 0.2 1.6 1 1 1 2 2 2 1 RIO1 family WaaY PF06176.6 EIM83428.1 - 0.00024 20.4 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EIM83428.1 - 0.0018 17.4 0.3 0.011 14.8 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM83428.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIM83428.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SLX9 PF15341.1 EIM83429.1 - 1.9e-22 79.9 3.2 2.2e-22 79.7 2.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 WD40_alt PF14077.1 EIM83430.1 - 0.083 12.5 0.7 26 4.5 0.0 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif ApoO PF09769.4 EIM83430.1 - 0.089 12.4 2.1 0.31 10.7 1.5 2.0 1 0 0 1 1 1 0 Apolipoprotein O APG6 PF04111.7 EIM83430.1 - 0.11 11.5 24.2 0.43 9.5 12.9 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4201 PF13870.1 EIM83430.1 - 0.13 11.6 20.7 0.56 9.6 7.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) IncA PF04156.9 EIM83430.1 - 0.44 10.1 26.8 1 8.9 11.4 2.8 2 0 0 2 2 2 0 IncA protein DUF4220 PF13968.1 EIM83430.1 - 0.46 9.5 2.4 0.76 8.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Reo_sigmaC PF04582.7 EIM83430.1 - 2.3 7.3 9.9 3.3 6.7 2.0 2.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 EIM83430.1 - 3.5 8.1 19.1 0.18 12.2 0.2 4.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 EIM83430.1 - 6.1 4.5 9.9 2.3 5.9 3.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family THOC7 PF05615.8 EIM83430.1 - 8.9 6.5 22.2 1.2 9.4 9.7 2.8 2 1 1 3 3 3 0 Tho complex subunit 7 Rad51 PF08423.6 EIM83431.1 - 0.0025 16.7 0.0 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIM83431.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 EIM83432.1 - 5.3e-26 90.9 0.0 6.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EIM83432.1 - 0.031 12.8 0.0 0.055 11.9 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PPR_2 PF13041.1 EIM83433.1 - 2.5e-28 97.7 0.0 9.3e-07 28.7 0.0 6.7 4 2 3 7 7 7 6 PPR repeat family PPR_3 PF13812.1 EIM83433.1 - 9.1e-22 75.4 8.4 2.6e-07 30.3 0.0 7.7 8 0 0 8 8 7 4 Pentatricopeptide repeat domain PPR PF01535.15 EIM83433.1 - 4.9e-15 54.3 0.0 0.00017 21.3 0.0 5.7 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 EIM83433.1 - 1e-14 53.6 0.0 1.8e-05 24.0 0.0 5.4 5 0 0 5 5 5 3 PPR repeat TPR_14 PF13428.1 EIM83433.1 - 7.7e-06 26.0 12.5 5.5 7.9 0.0 6.7 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM83433.1 - 0.0048 17.1 4.3 16 5.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM83433.1 - 0.016 15.8 11.3 0.068 13.8 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MRP-S27 PF10037.4 EIM83433.1 - 0.054 12.4 0.0 2.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 Glyco_trans_4_3 PF12000.3 EIM83433.1 - 0.057 13.0 0.2 1.2 8.6 0.0 2.8 2 1 1 3 3 3 0 Gkycosyl transferase family 4 group DUF1577 PF07614.6 EIM83433.1 - 0.16 10.8 0.1 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) TPR_4 PF07721.9 EIM83433.1 - 6.8 7.4 13.9 0.92 10.1 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EIM83434.1 - 9.6e-41 139.7 27.1 1.9e-39 135.5 18.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM83434.1 - 9.4e-16 57.4 38.6 2.7e-09 36.2 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 EIM83434.1 - 0.0026 17.8 17.1 0.022 14.8 1.0 4.0 3 1 1 4 4 4 2 Protein of unknown function, DUF606 Sm_multidrug_ex PF06695.6 EIM83434.1 - 0.027 14.6 2.0 0.041 14.0 0.6 2.0 2 0 0 2 2 2 0 Putative small multi-drug export protein SLS PF14611.1 EIM83435.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.7 EIM83436.1 - 4.7e-68 228.9 30.0 4.7e-68 228.9 20.8 5.0 3 1 2 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 EIM83436.1 - 1.6e-53 181.3 0.6 6.4e-53 179.4 0.0 2.3 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EIM83436.1 - 8.5e-43 145.6 6.8 8.5e-43 145.6 4.7 6.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) DUF2088 PF09861.4 EIM83436.1 - 1.1 8.1 5.0 0.36 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2088) DUF423 PF04241.10 EIM83437.1 - 6.9e-18 64.3 2.5 9.4e-18 63.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Acetyltransf_3 PF13302.1 EIM83439.1 - 2.3e-16 60.2 0.0 5.1e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM83439.1 - 8.8e-07 28.8 0.0 1.4e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIM83439.1 - 0.012 15.4 0.0 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM83439.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM83439.1 - 0.15 12.2 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SUR7 PF06687.7 EIM83440.1 - 3.8e-21 75.6 17.3 5.4e-21 75.1 12.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIM83440.1 - 0.0033 17.1 15.9 0.006 16.2 11.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Arginase PF00491.16 EIM83442.1 - 1.3e-81 273.9 0.6 1.7e-81 273.5 0.4 1.1 1 0 0 1 1 1 1 Arginase family WD40 PF00400.27 EIM83443.1 - 1.7e-22 78.3 20.5 1e-06 28.4 1.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40 PF00400.27 EIM83444.1 - 3.1e-49 163.1 17.7 2.2e-08 33.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIM83444.1 - 4e-06 26.6 0.0 0.0041 16.8 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EIM83444.1 - 6.5e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EIM83444.1 - 0.0034 15.5 0.1 0.42 8.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIM83444.1 - 0.026 13.2 0.6 0.82 8.3 0.3 2.7 1 1 2 3 3 3 0 Nup133 N terminal like Bax1-I PF01027.15 EIM83445.1 - 2.1e-35 122.2 8.3 2.1e-35 122.2 5.8 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF4079 PF13301.1 EIM83445.1 - 1.7 8.5 5.7 51 3.8 3.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) HEAT_2 PF13646.1 EIM83446.1 - 3.8e-05 23.8 0.1 0.013 15.7 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.18 EIM83446.1 - 0.00072 19.2 7.7 0.0011 18.7 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EIM83446.1 - 0.0068 16.1 3.8 0.051 13.2 0.0 3.1 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.17 EIM83446.1 - 0.016 15.2 1.8 8.7 6.7 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EIM83446.1 - 0.28 11.7 6.4 2.9 8.5 0.0 4.8 5 1 1 6 6 6 0 HEAT-like repeat OsmC PF02566.14 EIM83447.1 - 1.9e-06 27.9 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Ldh_2 PF02615.9 EIM83448.1 - 2.5e-85 286.1 0.0 3.8e-85 285.5 0.0 1.3 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase TMEM154 PF15102.1 EIM83449.1 - 0.016 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.14 EIM83449.1 - 1.1 8.8 2.8 0.38 10.3 0.1 1.6 2 0 0 2 2 2 0 Vpu protein Sin3_corepress PF08295.7 EIM83450.1 - 1.8e-31 107.8 0.0 3.9e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EIM83450.1 - 2.9e-31 106.8 8.2 2.4e-12 46.2 0.0 4.4 3 1 0 3 3 3 3 Paired amphipathic helix repeat TGT_C1 PF14809.1 EIM83451.1 - 0.076 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation Kelch_4 PF13418.1 EIM83453.1 - 0.054 13.2 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain SH3_1 PF00018.23 EIM83455.1 - 2.1e-11 43.0 0.2 3.9e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM83455.1 - 4.1e-09 35.8 0.0 1.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM83455.1 - 1.5e-08 34.0 0.0 3.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.20 EIM83456.1 - 2.7e-10 39.7 5.6 8.1e-10 38.2 4.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM83456.1 - 4.4e-10 39.4 11.4 7.1e-10 38.7 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM83456.1 - 1.3e-07 31.3 10.4 2.1e-07 30.6 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM83456.1 - 5.1e-06 26.0 6.3 7.8e-06 25.4 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM83456.1 - 1.8e-05 24.4 10.9 3.2e-05 23.7 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM83456.1 - 3.5e-05 23.4 3.6 3.5e-05 23.4 2.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIM83456.1 - 5.1e-05 22.9 7.9 9e-05 22.1 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Malectin PF11721.3 EIM83456.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Di-glucose binding within endoplasmic reticulum zf-rbx1 PF12678.2 EIM83456.1 - 0.03 14.4 5.0 0.072 13.2 3.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EIM83456.1 - 0.034 13.6 10.6 0.063 12.8 7.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EIM83456.1 - 0.05 13.1 6.8 0.12 11.9 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EIM83456.1 - 0.55 10.1 5.3 0.99 9.2 3.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Wbp11 PF09429.5 EIM83457.1 - 1.1e-19 70.1 9.7 2.4e-19 69.0 6.7 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.2 EIM83457.1 - 5.3e-17 62.0 7.6 5.3e-17 62.0 5.3 7.3 6 1 0 6 6 6 1 mRNA biogenesis factor Antimicrobial18 PF08130.6 EIM83457.1 - 0.15 11.9 1.4 0.67 9.8 0.2 2.2 2 0 0 2 2 2 0 Type A lantibiotic family Med21 PF11221.3 EIM83457.1 - 0.17 11.8 2.5 0.59 10.0 1.7 1.9 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HIT PF01230.18 EIM83459.1 - 2.1e-22 79.4 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIM83459.1 - 2.2e-06 27.8 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ku_PK_bind PF08785.6 EIM83460.1 - 1.1e-15 57.5 0.0 4.3e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.11 EIM83460.1 - 1.4e-12 47.4 0.1 6.3e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EIM83460.1 - 4.8e-08 32.7 0.0 3.9e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain EmrE PF13536.1 EIM83461.1 - 1.2e-11 44.7 5.1 1.2e-11 44.7 3.5 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIM83461.1 - 0.0044 17.0 8.2 0.0044 17.0 5.7 2.9 2 1 0 2 2 2 1 EamA-like transporter family Ribosomal_L36 PF00444.13 EIM83462.1 - 1.3e-17 63.4 8.8 1.3e-17 63.4 6.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L36 Translat_reg PF01818.12 EIM83462.1 - 0.035 13.6 0.1 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage translational regulator zf-C3HC4 PF00097.20 EIM83464.1 - 1e-08 34.6 5.6 1.8e-08 33.8 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM83464.1 - 3e-08 33.3 8.1 5.9e-08 32.4 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM83464.1 - 3.2e-08 33.4 8.7 6.8e-08 32.4 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM83464.1 - 9.5e-08 31.5 5.0 9.5e-08 31.5 3.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM83464.1 - 1.3e-06 27.9 6.0 2.5e-06 27.0 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM83464.1 - 0.0008 19.2 8.9 0.0019 18.0 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIM83464.1 - 0.0014 18.6 6.2 0.0054 16.8 4.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EIM83464.1 - 0.0043 16.7 2.4 0.006 16.2 0.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EIM83464.1 - 0.11 12.0 1.7 0.23 11.0 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EIM83464.1 - 0.16 11.8 3.6 0.33 10.8 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EIM83464.1 - 0.65 9.5 7.5 2.2 7.8 5.2 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger ComA PF02679.10 EIM83466.1 - 8.1e-72 241.1 0.0 9.2e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) CBM_5_12 PF02839.9 EIM83467.1 - 6.3e-15 54.4 33.3 5.5e-09 35.4 7.8 4.0 4 0 0 4 4 4 2 Carbohydrate binding domain Pkinase PF00069.20 EIM83468.1 - 3e-59 200.3 0.1 3.4e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83468.1 - 1.3e-20 73.6 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM83468.1 - 1e-06 28.7 0.2 6.5e-05 22.7 0.7 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM83468.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIM83468.1 - 0.038 13.3 0.2 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EIM83468.1 - 0.1 11.6 0.2 0.19 10.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 EIM83468.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.6 2 0 0 2 2 2 0 Aconitate B N-terminal domain SET PF00856.23 EIM83469.1 - 6.2e-11 42.8 0.0 8.9e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 SET domain CTDII PF01556.13 EIM83470.1 - 2.3e-28 97.9 0.4 1.2e-20 73.1 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EIM83470.1 - 7.7e-23 80.0 4.4 1.1e-22 79.4 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIM83470.1 - 5.3e-11 42.4 17.2 8.6e-11 41.7 12.0 1.3 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.1 EIM83470.1 - 0.84 9.3 7.4 3.3 7.3 5.3 1.9 1 1 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 EIM83470.1 - 1.7 8.3 8.8 1.9 8.2 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EIM83470.1 - 3.9 7.8 6.2 12 6.2 4.3 1.9 1 1 0 1 1 1 0 Cytochrome c3 MFS_1 PF07690.11 EIM83471.1 - 8.3e-41 139.8 39.9 1.8e-40 138.7 26.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM83471.1 - 8.1e-13 47.7 6.0 8.1e-13 47.7 4.1 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIM83471.1 - 1.2e-11 43.5 9.3 1.8e-11 42.9 6.1 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Choline_kinase PF01633.15 EIM83473.1 - 2.4e-51 174.2 0.0 3.4e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIM83473.1 - 9.3e-17 61.5 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIM83473.1 - 1.8e-06 27.3 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase zf-CCCH PF00642.19 EIM83474.1 - 1.1e-19 69.6 14.4 2.5e-11 42.9 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIM83474.1 - 0.15 12.1 11.4 0.077 13.0 0.7 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3437 PF11919.3 EIM83475.1 - 1.6e-30 104.6 0.0 6.2e-30 102.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EIM83475.1 - 1.8e-07 30.6 1.1 0.00023 20.9 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 EIM83475.1 - 0.0014 18.8 6.0 0.035 14.3 0.0 5.5 5 1 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EIM83475.1 - 0.003 17.9 0.1 0.036 14.4 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIM83475.1 - 0.0062 16.9 0.5 0.41 11.2 0.0 4.6 5 0 0 5 5 5 1 HEAT-like repeat DUF1546 PF07571.8 EIM83475.1 - 0.024 14.7 0.1 1.4 9.0 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Cnd1 PF12717.2 EIM83475.1 - 0.045 13.5 0.4 6.9 6.4 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Chalcone PF02431.10 EIM83476.1 - 8.8e-28 97.0 0.0 2.4e-27 95.6 0.0 1.7 1 1 0 1 1 1 1 Chalcone-flavanone isomerase DMA PF03474.9 EIM83476.1 - 1.6 8.6 3.2 5.9 6.8 0.0 2.9 3 0 0 3 3 3 0 DMRTA motif DUF3784 PF12650.2 EIM83477.1 - 0.049 13.5 0.4 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1516 PF07457.6 EIM83477.1 - 0.073 13.1 1.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF3112 PF11309.3 EIM83477.1 - 0.085 12.6 5.9 0.53 10.0 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Herpes_LMP1 PF05297.6 EIM83477.1 - 0.15 10.9 0.4 0.27 10.0 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4149 PF13664.1 EIM83477.1 - 1 9.4 4.1 0.49 10.4 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF998 PF06197.8 EIM83477.1 - 1.2 8.3 6.7 4.4 6.5 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF998) zf-RING_2 PF13639.1 EIM83478.1 - 5.8e-06 26.0 5.5 9.6e-06 25.3 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM83478.1 - 1.6e-05 24.4 4.6 2.6e-05 23.7 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM83478.1 - 0.00013 21.5 6.8 0.00033 20.2 4.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM83478.1 - 0.00059 19.7 8.5 0.0015 18.5 5.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM83478.1 - 0.00061 19.4 6.3 0.0015 18.1 4.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Rootletin PF15035.1 EIM83478.1 - 0.0016 18.4 3.5 0.0016 18.4 2.4 2.2 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 EIM83478.1 - 0.016 15.5 16.8 0.25 11.6 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-C3HC4_4 PF15227.1 EIM83478.1 - 0.023 14.5 1.7 0.023 14.5 1.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIM83478.1 - 0.033 14.2 4.1 0.078 13.1 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EIM83478.1 - 0.067 13.0 3.5 0.12 12.2 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IncA PF04156.9 EIM83478.1 - 0.085 12.4 21.0 0.013 15.0 11.4 1.8 1 1 1 2 2 2 0 IncA protein HOOK PF05622.7 EIM83478.1 - 0.11 10.3 19.9 0.14 9.9 13.8 1.1 1 0 0 1 1 1 0 HOOK protein DUF572 PF04502.8 EIM83478.1 - 0.33 10.1 15.5 0.47 9.6 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DivIC PF04977.10 EIM83478.1 - 0.63 9.5 15.1 2.7 7.5 4.5 2.7 2 0 0 2 2 2 0 Septum formation initiator AAA_13 PF13166.1 EIM83478.1 - 1 7.7 12.3 1.4 7.2 8.6 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.1 EIM83478.1 - 1.4 8.5 9.6 4.1 7.0 6.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TMF_DNA_bd PF12329.3 EIM83478.1 - 1.4 8.8 29.5 0.064 13.0 8.5 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TATR PF03430.8 EIM83478.1 - 2.8 6.4 12.6 3.8 6.0 8.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF904 PF06005.7 EIM83478.1 - 3.2 8.0 19.6 6.7 7.0 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Exonuc_VII_L PF02601.10 EIM83478.1 - 8.3 5.5 14.8 12 4.9 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TIM21 PF08294.6 EIM83479.1 - 1e-21 77.0 0.0 3.5e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 TIM21 SGT1 PF07093.6 EIM83480.1 - 1.2e-134 449.9 23.4 2e-126 422.7 1.7 2.2 2 0 0 2 2 2 2 SGT1 protein Clat_adaptor_s PF01217.15 EIM83481.1 - 3.5e-43 146.7 0.9 6.6e-43 145.8 0.6 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.9 EIM83482.1 - 2.4e-37 127.6 0.7 3.9e-37 126.9 0.5 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Nramp PF01566.13 EIM83483.1 - 2.4e-83 279.8 21.7 1.1e-82 277.6 15.0 1.9 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Catalase PF00199.14 EIM83484.1 - 1.6e-163 543.8 0.0 2.3e-163 543.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIM83484.1 - 8.7e-19 67.1 0.2 2.1e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIM83484.1 - 8.7e-08 31.7 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIM83484.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase zf-C2H2 PF00096.21 EIM83485.1 - 9.7e-09 35.0 19.6 1.2e-05 25.3 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM83485.1 - 6e-08 32.4 17.2 7.5e-05 22.7 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM83485.1 - 0.00022 21.3 4.6 0.003 17.7 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM83485.1 - 0.022 14.9 5.6 0.27 11.4 0.9 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 EIM83485.1 - 0.095 12.2 0.8 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EIM83485.1 - 3.5 7.3 4.7 14 5.4 0.2 2.2 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MCM PF00493.18 EIM83486.1 - 4.6e-140 466.1 0.0 6e-140 465.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIM83486.1 - 1.1e-18 67.8 0.1 3.2e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIM83486.1 - 1.4e-06 27.6 0.0 0.00039 19.6 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIM83486.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIM83486.1 - 0.00059 19.4 0.1 0.0028 17.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF134 PF02001.11 EIM83486.1 - 0.047 13.5 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF134 MitMem_reg PF13012.1 EIM83487.1 - 5.7e-22 77.9 0.0 8.3e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIM83487.1 - 2e-10 40.4 0.0 3.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease F-box PF00646.28 EIM83488.1 - 0.00061 19.3 0.1 0.0019 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain HlyU PF10115.4 EIM83488.1 - 0.024 14.4 0.1 9 6.2 0.0 2.4 2 0 0 2 2 2 0 Transcriptional activator HlyU DUF4149 PF13664.1 EIM83489.1 - 4e-20 71.7 4.8 4e-20 71.7 3.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) SLAC1 PF03595.12 EIM83489.1 - 0.015 13.9 7.5 0.025 13.2 5.2 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel LRR_9 PF14580.1 EIM83490.1 - 9.7e-58 194.5 0.1 1.6e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EIM83490.1 - 5.7e-13 48.4 6.2 9.1e-08 31.7 1.9 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EIM83490.1 - 1.2e-12 47.1 11.6 1e-06 28.2 0.3 3.9 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM83490.1 - 7.8e-06 25.2 5.5 0.61 10.3 0.2 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 EIM83490.1 - 0.00035 20.3 3.0 0.6 10.3 0.1 4.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EIM83490.1 - 0.00054 19.7 7.4 0.95 9.9 0.2 4.8 6 0 0 6 6 6 1 Leucine rich repeat Syja_N PF02383.13 EIM83491.1 - 3e-86 289.0 0.0 3.8e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain GRAM PF02893.15 EIM83493.1 - 1.6e-13 49.9 0.0 3.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Pkinase PF00069.20 EIM83494.1 - 4.9e-62 209.4 0.0 8.8e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83494.1 - 1.3e-25 89.9 0.0 6.5e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EIM83494.1 - 3.8e-05 24.1 4.8 3.8e-05 24.1 3.3 3.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EIM83494.1 - 0.0018 17.3 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.19 EIM83494.1 - 0.0019 17.9 0.0 0.044 13.5 0.1 2.7 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.1 EIM83494.1 - 0.012 14.5 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like LCD1 PF09798.4 EIM83494.1 - 1.3 6.9 2.6 2.9 5.7 1.8 1.5 1 0 0 1 1 1 0 DNA damage checkpoint protein FPN1 PF06963.7 EIM83495.1 - 0.049 12.0 0.1 0.067 11.5 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Malic_M PF03949.10 EIM83496.1 - 5.7e-77 258.7 0.0 7.8e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIM83496.1 - 3.8e-57 192.8 0.0 5.4e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PcrB PF01884.12 EIM83496.1 - 0.063 12.5 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 PcrB family Nop10p PF04135.7 EIM83497.1 - 5.3e-20 70.8 0.1 6.2e-20 70.6 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.15 EIM83498.1 - 3.3e-39 133.9 0.0 4.4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIM83498.1 - 0.0027 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM83498.1 - 0.0094 16.0 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Flavin_Reduct PF01613.13 EIM83500.1 - 7.4e-24 84.3 0.0 1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HATPase_c PF02518.21 EIM83501.1 - 7.3e-29 99.7 0.0 2.2e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM83501.1 - 1.5e-19 70.0 0.0 2.5e-18 66.1 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.1 EIM83501.1 - 1.9e-17 63.8 2.4 7.4e-16 58.6 0.6 3.7 3 0 0 3 3 3 1 AAA ATPase domain HisKA PF00512.20 EIM83501.1 - 2.1e-15 56.4 0.2 8.3e-15 54.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EIM83501.1 - 3.9e-12 45.8 0.0 8.1e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83501.1 - 2.5e-09 36.6 0.0 4.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.1 EIM83501.1 - 1.1e-08 35.2 0.0 3.2e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EIM83501.1 - 3.9e-08 33.9 0.0 1.4e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.1 EIM83501.1 - 0.00039 20.5 0.0 0.062 13.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 EIM83501.1 - 0.0044 16.6 0.4 0.02 14.5 0.3 2.2 1 1 0 1 1 1 1 NACHT domain TPR_12 PF13424.1 EIM83501.1 - 0.066 13.1 7.3 0.66 9.9 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HATPase_c_3 PF13589.1 EIM83501.1 - 0.068 12.8 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF258 PF03193.11 EIM83501.1 - 0.27 10.4 0.0 0.61 9.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1986 PF09342.6 EIM83501.1 - 0.37 10.0 0.0 0.72 9.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DEAD PF00270.24 EIM83502.1 - 3.7e-36 124.1 0.1 6.5e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM83502.1 - 9.6e-24 83.0 0.0 4.6e-23 80.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM83502.1 - 0.00033 20.5 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EIM83503.1 - 9.3e-54 179.1 0.7 7.4e-19 67.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 EIM83505.1 - 2e-38 131.5 0.1 3.1e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM83505.1 - 6.1e-22 77.2 0.1 1.4e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM83505.1 - 3e-05 23.9 0.1 0.00012 22.0 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIM83505.1 - 0.00026 19.8 0.0 0.0004 19.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Sigma70_ner PF04546.8 EIM83505.1 - 0.0073 15.9 6.5 0.0073 15.9 4.5 1.8 2 0 0 2 2 2 1 Sigma-70, non-essential region NOA36 PF06524.7 EIM83505.1 - 0.38 9.9 11.0 0.69 9.1 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EIM83505.1 - 0.6 8.5 10.9 1.1 7.6 7.6 1.3 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 EIM83505.1 - 0.83 8.7 8.9 0.048 12.8 2.5 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Nucleo_P87 PF07267.6 EIM83505.1 - 1 7.9 5.3 2.2 6.8 3.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TLP-20 PF06088.6 EIM83505.1 - 1.2 8.8 5.1 2.3 7.8 3.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleoplasmin PF03066.10 EIM83505.1 - 1.3 8.5 18.1 3.1 7.3 12.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EIM83505.1 - 1.9 8.2 13.0 0.072 12.8 4.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.8 EIM83505.1 - 3 5.4 15.6 4.4 4.9 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 EIM83505.1 - 4 5.3 10.5 7 4.5 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Mg_trans_NIPA PF05653.9 EIM83506.1 - 3.4e-20 72.2 14.1 6.8e-12 44.9 1.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIM83506.1 - 0.001 19.2 4.3 0.001 19.2 3.0 3.0 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIM83506.1 - 0.0032 17.4 7.1 0.0032 17.4 4.9 3.2 3 0 0 3 3 3 1 EamA-like transporter family AAA_2 PF07724.9 EIM83507.1 - 9.6e-52 175.3 0.0 5.6e-47 159.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIM83507.1 - 9.3e-25 87.3 0.0 1.5e-13 51.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIM83507.1 - 6.6e-24 83.6 2.1 1.1e-23 82.9 0.2 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EIM83507.1 - 1.1e-17 63.7 10.6 3.1e-12 46.2 0.2 4.2 4 0 0 4 4 4 3 Clp amino terminal domain AAA_5 PF07728.9 EIM83507.1 - 3.8e-15 55.8 0.0 6.4e-08 32.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM83507.1 - 5.2e-12 46.1 8.4 9.6e-05 22.4 0.0 5.7 4 3 1 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 EIM83507.1 - 3.7e-10 40.0 0.1 0.0039 17.3 0.0 4.2 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIM83507.1 - 6.8e-08 32.1 0.0 8.2e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EIM83507.1 - 9e-08 32.4 0.0 0.00035 20.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIM83507.1 - 3.4e-07 29.8 0.3 0.001 18.5 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EIM83507.1 - 1.1e-05 24.6 0.0 0.012 14.8 0.0 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIM83507.1 - 1.2e-05 26.0 7.1 0.0064 17.3 0.8 3.8 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIM83507.1 - 2.2e-05 23.6 0.6 0.006 15.6 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EIM83507.1 - 4.6e-05 23.0 0.4 0.3 10.8 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain AAA_24 PF13479.1 EIM83507.1 - 8.9e-05 22.1 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIM83507.1 - 0.00026 21.1 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EIM83507.1 - 0.00026 20.8 0.0 0.2 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIM83507.1 - 0.0014 18.6 0.6 0.83 9.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EIM83507.1 - 0.0014 18.2 0.0 0.52 9.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EIM83507.1 - 0.0029 17.9 0.7 2.4 8.4 0.0 3.5 3 0 0 3 3 3 1 ABC transporter PhoH PF02562.11 EIM83507.1 - 0.0058 15.8 0.0 0.7 9.0 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein Arch_ATPase PF01637.13 EIM83507.1 - 0.0064 16.2 4.8 0.69 9.5 0.0 4.3 4 1 1 5 5 4 1 Archaeal ATPase AAA_29 PF13555.1 EIM83507.1 - 0.024 14.1 0.0 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EIM83507.1 - 0.025 14.3 0.0 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.6 EIM83507.1 - 0.037 13.9 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Torsin DUF258 PF03193.11 EIM83507.1 - 0.04 13.0 0.0 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIM83507.1 - 0.05 13.2 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EIM83507.1 - 0.052 13.3 0.0 5.1 6.8 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EIM83507.1 - 0.056 12.8 2.7 7.4 5.9 0.0 4.0 3 1 0 3 3 3 0 AAA-like domain CbiA PF01656.18 EIM83507.1 - 0.056 12.8 0.0 6 6.2 0.0 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.6 EIM83507.1 - 0.067 12.8 0.0 31 4.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIM83507.1 - 0.1 12.0 3.3 8.8 5.6 0.0 3.5 3 1 1 4 4 4 0 AAA domain KaiC PF06745.8 EIM83507.1 - 2 7.4 5.7 6 5.9 0.0 3.6 3 1 1 4 4 4 0 KaiC zf-CHCC PF10276.4 EIM83508.1 - 1.2e-16 60.2 1.3 1.6e-16 59.8 0.9 1.2 1 0 0 1 1 1 1 Zinc-finger domain PRCC PF10253.4 EIM83508.1 - 0.12 13.0 1.4 0.13 12.9 1.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF566 PF04484.7 EIM83508.1 - 1.4 8.3 6.7 1.5 8.2 4.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pkinase PF00069.20 EIM83509.1 - 3.6e-57 193.4 0.0 1.3e-56 191.6 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83509.1 - 4e-24 85.0 0.0 8.8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RR_TM4-6 PF06459.7 EIM83509.1 - 0.79 9.5 4.0 1.4 8.7 2.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran_N PF13793.1 EIM83510.1 - 1.2e-43 147.5 0.2 3.3e-43 146.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIM83510.1 - 2.8e-39 134.7 1.6 1.1e-32 113.3 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIM83510.1 - 1.9e-11 43.7 0.4 1.9e-10 40.5 0.4 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIM83510.1 - 0.00011 21.4 0.1 0.00019 20.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DCP2 PF05026.8 EIM83511.1 - 1.1e-35 121.4 0.2 1.7e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EIM83511.1 - 3.5e-12 46.1 0.0 7.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF2223 PF09985.4 EIM83511.1 - 0.061 12.6 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2223) INCENP_ARK-bind PF03941.10 EIM83512.1 - 1.6e-15 56.6 0.1 3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF3292 PF11696.3 EIM83513.1 - 6.3e-06 24.3 4.5 1e-05 23.6 0.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 EIM83513.1 - 0.00056 19.4 1.2 0.0034 16.8 0.1 2.3 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 EIM83513.1 - 0.0039 16.8 12.1 0.15 11.6 0.7 2.4 2 0 0 2 2 2 2 Reticulon PRCC PF10253.4 EIM83513.1 - 7.4 7.2 8.2 1.9 9.1 0.6 2.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Rad21_Rec8_N PF04825.8 EIM83514.1 - 3.9e-23 81.5 0.0 7.5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EIM83514.1 - 4.8e-09 35.2 0.0 9.1e-09 34.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EIM83514.1 - 0.25 10.8 0.0 0.25 10.8 0.0 2.1 3 0 0 3 3 3 0 ScpA/B protein NUDIX PF00293.23 EIM83515.1 - 3.9e-27 94.5 0.0 5.5e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2532 PF10811.3 EIM83515.1 - 0.14 12.0 0.2 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2532) O-FucT PF10250.4 EIM83516.1 - 1.9e-07 30.5 0.0 9.2e-05 21.7 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase His_Phos_1 PF00300.17 EIM83517.1 - 4e-19 69.2 0.0 8.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PAT1 PF09770.4 EIM83517.1 - 0.15 10.3 29.4 0.21 9.7 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MPC PF03650.8 EIM83518.1 - 8e-38 129.0 0.2 9.8e-38 128.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) EndoU_bacteria PF14436.1 EIM83518.1 - 0.058 13.2 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease DNA_ligase_A_M PF01068.16 EIM83519.1 - 5.1e-63 212.0 0.5 8.5e-63 211.3 0.4 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIM83519.1 - 1.8e-51 174.4 0.7 3.3e-51 173.5 0.5 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIM83519.1 - 2.4e-26 91.9 0.0 7.2e-26 90.4 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EIM83519.1 - 0.018 14.6 0.3 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Metallophos PF00149.23 EIM83520.1 - 5.3e-42 143.4 0.1 6.5e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S17 PF00366.15 EIM83521.1 - 5.9e-30 103.1 1.0 1.1e-29 102.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 MMtag PF10159.4 EIM83521.1 - 0.039 14.0 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Kinase phosphorylation protein Polysacc_synt_3 PF13440.1 EIM83522.1 - 0.051 13.0 0.4 0.079 12.4 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein OppC_N PF12911.2 EIM83522.1 - 0.32 10.4 1.0 0.83 9.0 0.7 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TrbL PF04610.9 EIM83522.1 - 0.66 9.6 5.2 2.7 7.6 3.6 2.0 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Adeno_E3_CR2 PF02439.10 EIM83522.1 - 0.7 9.4 1.4 1.3 8.6 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Aldo_ket_red PF00248.16 EIM83523.1 - 5.4e-47 159.9 0.0 6.4e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM83524.1 - 3.9e-43 147.2 0.0 6.7e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family SGS PF05002.10 EIM83525.1 - 1.8e-29 101.2 1.8 2.7e-29 100.7 1.3 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EIM83525.1 - 3.6e-06 27.4 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CS domain CsgF PF10614.4 EIM83525.1 - 0.1 12.5 0.2 13 5.8 0.1 2.2 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein GST_C PF00043.20 EIM83526.1 - 1.1e-05 25.3 0.3 2.9e-05 23.9 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM83526.1 - 2.4e-05 24.1 0.2 6.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM83526.1 - 4e-05 23.7 0.1 0.00015 21.9 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM83526.1 - 0.00032 20.6 0.0 0.00079 19.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM83526.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cas_Csd1 PF09709.5 EIM83526.1 - 0.056 11.7 0.1 0.081 11.1 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Galactosyl_T PF01762.16 EIM83527.1 - 9.5e-07 28.5 0.0 0.0011 18.6 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase Aa_trans PF01490.13 EIM83528.1 - 5.7e-31 107.4 35.5 6.6e-31 107.2 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Isochorismatase PF00857.15 EIM83529.1 - 8.3e-09 35.6 0.0 3e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family DUF2095 PF09868.4 EIM83529.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) SKG6 PF08693.5 EIM83530.1 - 3.2 7.1 5.5 2.5 7.5 0.9 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ras PF00071.17 EIM83531.1 - 6.3e-54 181.7 0.0 7.6e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM83531.1 - 1.8e-17 63.8 0.0 2.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM83531.1 - 1.1e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM83531.1 - 1.2e-06 28.1 0.0 1.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM83531.1 - 6e-05 22.9 0.0 8.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIM83531.1 - 7e-05 22.0 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIM83531.1 - 0.0013 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EIM83531.1 - 0.0031 17.6 0.1 0.0052 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM83531.1 - 0.006 16.5 0.4 0.0098 15.8 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 EIM83531.1 - 0.016 14.7 0.0 0.84 9.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIM83531.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EIM83531.1 - 0.025 14.8 0.1 0.075 13.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter UbiD PF01977.11 EIM83531.1 - 0.045 12.1 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase KaiC PF06745.8 EIM83531.1 - 0.048 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 KaiC Methyltransf_25 PF13649.1 EIM83531.1 - 0.051 13.9 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2075 PF09848.4 EIM83531.1 - 0.052 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.4 EIM83531.1 - 0.054 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.13 EIM83531.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Septin D-ser_dehydrat PF14031.1 EIM83532.1 - 9.4e-18 64.2 0.2 3.1e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EIM83532.1 - 4.2e-15 55.8 0.2 5.7e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ribonuc_L-PSP PF01042.16 EIM83533.1 - 1.7e-34 118.2 0.0 2e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 EIM83534.1 - 2.5e-31 108.6 28.0 9.5e-31 106.7 19.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UCR_TM PF02921.9 EIM83535.1 - 2.2e-16 59.8 0.6 4.1e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EIM83535.1 - 4.8e-16 58.1 0.1 7.6e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain dCMP_cyt_deam_1 PF00383.17 EIM83536.1 - 2.2e-13 49.7 0.1 6.1e-13 48.2 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Polysacc_deac_1 PF01522.16 EIM83538.1 - 5.4e-30 103.5 0.0 2.9e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIM83538.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NAP PF00956.13 EIM83539.1 - 2.2e-32 112.1 8.2 6e-32 110.7 5.7 1.7 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EIM83539.1 - 0.0075 16.3 3.6 0.019 15.1 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EIM83539.1 - 0.077 12.5 4.3 0.12 11.9 3.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin YL1 PF05764.8 EIM83539.1 - 0.13 11.9 3.7 0.18 11.4 2.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Pyr_redox_3 PF13738.1 EIM83540.1 - 1.4e-27 97.1 0.0 9.7e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM83540.1 - 4e-15 56.2 0.0 2.5e-13 50.3 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM83540.1 - 5.4e-14 51.2 0.1 4.8e-13 48.1 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EIM83540.1 - 2.6e-09 36.5 0.1 2.3e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 EIM83540.1 - 1.1e-08 34.3 0.1 4.7e-07 29.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIM83540.1 - 3.4e-08 33.7 0.2 0.0021 18.3 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM83540.1 - 6e-07 28.6 0.3 0.0022 16.9 0.1 3.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.17 EIM83540.1 - 1.7e-06 27.1 0.0 0.0055 15.6 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM83540.1 - 5.7e-06 26.2 0.0 5.3e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EIM83540.1 - 1.3e-05 25.2 0.1 0.028 14.4 0.0 2.6 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIM83540.1 - 6.3e-05 22.7 0.2 1.3 8.7 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EIM83540.1 - 0.00025 20.2 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EIM83540.1 - 0.00047 19.1 0.1 0.0047 15.8 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM83540.1 - 0.0034 15.9 0.0 0.011 14.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EIM83540.1 - 0.0061 15.6 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family XdhC_C PF13478.1 EIM83540.1 - 0.0085 16.4 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.7 EIM83540.1 - 0.012 14.9 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EIM83540.1 - 0.02 14.5 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIM83540.1 - 0.026 14.7 0.1 11 6.3 0.0 3.4 3 1 0 3 3 3 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 EIM83540.1 - 0.027 14.5 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain UDPG_MGDP_dh_N PF03721.9 EIM83540.1 - 0.054 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EIM83540.1 - 0.11 11.5 0.1 0.35 9.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EIM83540.1 - 0.17 11.8 0.0 0.74 9.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EIM83540.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynactin PF12455.3 EIM83541.1 - 2.8e-82 275.7 1.3 2.8e-82 275.7 0.9 2.9 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EIM83541.1 - 1.2e-20 72.9 1.9 2.4e-20 72.0 1.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain F-box-like PF12937.2 EIM83542.1 - 6.2e-11 41.8 0.3 6.2e-11 41.8 0.2 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIM83542.1 - 1e-06 28.2 1.5 1.8e-06 27.4 0.1 2.3 2 0 0 2 2 2 1 F-box domain PfkB PF00294.19 EIM83543.1 - 4.5e-64 216.4 0.3 5.1e-64 216.2 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UbiA PF01040.13 EIM83544.1 - 1e-23 83.8 5.5 1.3e-23 83.5 3.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ABC_tran PF00005.22 EIM83545.1 - 4.1e-52 176.1 0.0 1e-24 87.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM83545.1 - 2.9e-24 86.5 1.9 3.7e-07 30.4 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 EIM83545.1 - 5.6e-21 74.9 47.5 9.3e-14 51.2 18.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.1 EIM83545.1 - 3e-08 34.2 1.9 0.0027 18.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM83545.1 - 3.8e-05 23.1 1.1 0.15 11.6 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIM83545.1 - 6.6e-05 22.2 0.1 14 4.8 0.0 4.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EIM83545.1 - 0.00053 19.1 0.0 0.29 10.1 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 EIM83545.1 - 0.00083 19.2 1.1 2.4 8.1 0.0 4.3 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIM83545.1 - 0.0029 17.3 1.1 0.76 9.5 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 EIM83545.1 - 0.0047 16.1 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM83545.1 - 0.028 14.5 0.8 19 5.4 0.0 3.5 2 2 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIM83545.1 - 0.042 13.2 0.6 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EIM83545.1 - 0.044 13.3 0.2 14 5.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIM83545.1 - 0.066 12.2 0.1 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.1 EIM83545.1 - 2 6.7 0.3 43 2.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF4396 PF14342.1 EIM83546.1 - 0.038 14.1 5.9 0.99 9.5 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Chitin_synth_2 PF03142.10 EIM83547.1 - 5.3e-280 929.3 0.0 6.9e-280 928.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM83547.1 - 1.5e-16 60.7 0.2 3.3e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM83547.1 - 6.3e-15 55.5 0.0 6.9e-14 52.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIM83547.1 - 0.00045 19.5 0.0 0.0026 17.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIM83547.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 FA_desaturase PF00487.19 EIM83548.1 - 0.22 10.9 6.9 0.62 9.4 2.2 2.7 2 1 0 2 2 2 0 Fatty acid desaturase F-box-like PF12937.2 EIM83549.1 - 0.0022 17.6 1.6 0.0022 17.6 1.1 3.5 3 1 0 3 3 3 1 F-box-like LRR_8 PF13855.1 EIM83549.1 - 0.073 12.8 2.7 0.29 10.9 0.2 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EIM83549.1 - 0.12 12.0 3.7 0.24 11.0 0.2 3.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM83550.1 - 5.3e-05 22.8 2.1 5.3e-05 22.8 1.5 2.7 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM83550.1 - 0.044 13.4 0.4 38 4.0 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM83550.1 - 0.065 13.0 0.2 25 4.7 0.0 4.0 5 1 0 5 5 5 0 Leucine rich repeat Polysacc_deac_1 PF01522.16 EIM83551.1 - 0.0013 18.3 2.5 0.0037 16.8 0.5 2.7 2 1 0 2 2 2 1 Polysaccharide deacetylase PAP_assoc PF03828.14 EIM83552.1 - 2.4e-08 33.7 0.9 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIM83552.1 - 0.00011 22.4 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.1 EIM83552.1 - 0.0044 16.9 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) DUF4629 PF15442.1 EIM83553.1 - 0.017 15.2 2.0 0.022 14.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DAP PF15228.1 EIM83553.1 - 2.7 8.7 10.0 2.7 8.7 5.9 1.8 1 1 1 2 2 2 0 Death-associated protein Ribosomal_L28e PF01778.12 EIM83554.1 - 8.3e-28 97.1 0.0 1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ribosomal_S4 PF00163.14 EIM83555.1 - 1.1e-27 96.2 1.1 2.1e-27 95.3 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIM83555.1 - 4.1e-12 45.3 1.5 4.1e-12 45.3 1.0 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EIM83556.1 - 2.8e-37 126.5 4.3 3.8e-37 126.0 2.7 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.12 EIM83556.1 - 0.011 14.9 0.1 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Surface antigen Methyltransf_16 PF10294.4 EIM83558.1 - 7.4e-14 51.5 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM83558.1 - 0.00011 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM83558.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EIM83558.1 - 0.0028 18.1 0.0 0.0068 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM83558.1 - 0.031 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIM83558.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EIM83558.1 - 0.11 12.1 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 EIM83560.1 - 3e-71 240.3 0.0 3.7e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 EIM83563.1 - 3.6e-25 87.3 0.1 7.2e-13 47.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM83563.1 - 4.9e-17 61.5 0.0 7.7e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM83563.1 - 2.5e-16 59.3 0.0 4.5e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIM83563.1 - 0.0018 17.9 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 EIM83563.1 - 0.008 15.7 0.2 0.13 11.8 0.1 2.2 2 0 0 2 2 2 1 Calcipressin EB PF01683.13 EIM83564.1 - 3.5 7.7 7.0 1e+02 3.0 4.9 2.3 1 1 0 1 1 1 0 EB module LysM PF01476.15 EIM83566.1 - 5.6e-16 58.1 0.0 9.3e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF3309 PF11752.3 EIM83566.1 - 0.052 13.3 3.1 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) MARVEL PF01284.18 EIM83567.1 - 3.4e-11 43.1 14.5 4.6e-11 42.7 10.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain Lig_chan PF00060.21 EIM83567.1 - 1 9.0 9.2 0.17 11.5 3.5 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel Nucleoplasmin PF03066.10 EIM83568.1 - 1.6 8.1 7.9 2.5 7.6 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 EIM83568.1 - 3 5.9 5.6 4 5.5 3.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TPR_14 PF13428.1 EIM83569.1 - 0.17 12.6 1.4 5 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RdRP PF05183.7 EIM83571.1 - 4.1e-114 382.4 0.0 7.2e-114 381.5 0.0 1.3 2 0 0 2 2 2 1 RNA dependent RNA polymerase NAC PF01849.13 EIM83571.1 - 0.097 12.2 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 NAC domain Alginate_lyase2 PF08787.6 EIM83571.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase 2-Hacid_dh_C PF02826.14 EIM83572.1 - 1.1e-54 184.2 0.0 2.9e-54 182.8 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM83572.1 - 2.8e-09 36.5 0.0 6.4e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM83572.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CcmD PF04995.9 EIM83573.1 - 0.086 12.5 0.2 0.086 12.5 0.1 2.8 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RhoGEF PF00621.15 EIM83574.1 - 1.3e-36 126.1 0.0 1.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EIM83574.1 - 2.6e-18 65.6 8.3 4.4e-18 64.9 5.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EIM83574.1 - 0.0067 16.6 0.0 0.025 14.7 0.0 2.0 1 1 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EIM83574.1 - 0.1 12.4 5.1 0.2 11.5 3.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_L11_N PF03946.9 EIM83575.1 - 0.038 13.4 0.1 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain LepA_C PF06421.7 EIM83575.1 - 0.12 12.3 1.2 0.38 10.6 0.2 2.1 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus p450 PF00067.17 EIM83576.1 - 1.8e-59 201.4 0.0 3.7e-59 200.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 zf-DHHC PF01529.15 EIM83578.1 - 5.2e-41 139.9 3.2 5.2e-41 139.9 2.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EIM83578.1 - 0.056 13.2 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily ABC2_membrane_2 PF12679.2 EIM83578.1 - 0.74 8.6 2.6 1.2 7.9 1.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein SAS4 PF15460.1 EIM83579.1 - 5.2e-06 26.2 1.4 5.2e-06 26.2 1.0 2.0 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EIM83579.1 - 5.5e-05 23.6 4.9 5.5e-05 23.6 3.4 3.6 2 1 0 3 3 3 1 PEHE domain Gar1 PF04410.9 EIM83580.1 - 2.3e-29 101.8 0.1 2.3e-29 101.8 0.1 2.4 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region EF_TS PF00889.14 EIM83581.1 - 4e-19 68.8 0.0 7.9e-18 64.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.26 EIM83581.1 - 6.8e-05 22.5 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EIM83581.1 - 0.01 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Glyco_hydro_15 PF00723.16 EIM83582.1 - 2.7e-93 312.9 0.0 3.2e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EIM83582.1 - 9.7e-31 105.2 1.6 2.6e-30 103.8 1.1 1.8 1 0 0 1 1 1 1 Starch binding domain Glyco_transf_18 PF15024.1 EIM83583.1 - 9.7e-11 40.7 0.0 1.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 MRJP PF03022.11 EIM83584.1 - 1.5e-27 96.5 0.0 5.1e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 EIM83584.1 - 0.00031 20.5 1.0 36 4.5 0.0 5.3 5 0 0 5 5 5 1 NHL repeat SGL PF08450.7 EIM83584.1 - 0.022 14.1 0.0 0.19 11.0 0.0 2.5 3 1 1 4 4 4 0 SMP-30/Gluconolaconase/LRE-like region Peptidase_M16 PF00675.15 EIM83585.1 - 5.5e-39 133.3 0.0 9.7e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIM83585.1 - 2e-38 131.9 0.0 4.5e-38 130.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase M16 inactive domain BRCA-2_OB1 PF09103.5 EIM83586.1 - 3.4e-30 104.1 0.0 5.8e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EIM83586.1 - 4.2e-07 29.7 0.1 6.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 BRCA2, helical Taxilin PF09728.4 EIM83587.1 - 2.2e-14 53.2 36.5 2.1e-07 30.3 14.4 2.6 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 EIM83587.1 - 1.5e-06 27.8 0.2 0.064 12.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF342 PF03961.8 EIM83587.1 - 0.55 8.5 20.8 0.17 10.3 7.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2252 PF10009.4 EIM83587.1 - 3.3 6.5 20.7 0.049 12.5 8.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) IF-2B PF01008.12 EIM83587.1 - 4 6.3 8.3 3.3 6.5 4.5 1.7 1 1 1 2 2 2 0 Initiation factor 2 subunit family UDPGP PF01704.13 EIM83590.1 - 4.6e-48 163.7 0.0 6.1e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EIM83590.1 - 0.003 17.6 0.0 0.0056 16.7 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Cellulase PF00150.13 EIM83591.1 - 9.3e-13 48.0 0.3 9.3e-13 48.0 0.2 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Lum_binding PF00677.12 EIM83593.1 - 7.9e-34 115.4 0.0 1e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Zn_clus PF00172.13 EIM83594.1 - 1.6e-08 34.3 5.5 2.3e-08 33.7 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4557 PF15101.1 EIM83594.1 - 0.29 10.9 6.7 0.39 10.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Haem_bd PF14376.1 EIM83594.1 - 1.2 8.8 7.5 2.4 7.8 5.2 1.5 1 0 0 1 1 1 0 Haem-binding domain XRCC4 PF06632.7 EIM83594.1 - 2.8 6.6 5.3 4.9 5.9 3.7 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HLH PF00010.21 EIM83595.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 EIM83596.1 - 5.6e-62 208.7 0.5 5.6e-62 208.7 0.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIM83596.1 - 1e-23 84.9 0.2 2.3e-23 83.7 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM83596.1 - 6.9e-12 45.9 0.0 1.3e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIM83596.1 - 2.2e-06 27.0 0.0 6.6e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM83596.1 - 0.00061 19.4 0.1 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-MYND PF01753.13 EIM83597.1 - 2.2e-11 43.4 14.8 4e-11 42.5 10.2 1.4 1 0 0 1 1 1 1 MYND finger YukC PF10140.4 EIM83597.1 - 0.14 10.7 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FXR1P_C PF12235.3 EIM83599.1 - 9.2 6.3 13.1 3.1 7.8 4.3 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal ADH_zinc_N PF00107.21 EIM83601.1 - 9.9e-12 44.5 0.0 2.4e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM83601.1 - 6.5e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM83601.1 - 0.045 14.6 0.0 0.082 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_S10 PF00450.17 EIM83602.1 - 7.1e-113 377.8 0.0 8.7e-113 377.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIM83602.1 - 3.8e-06 26.9 0.0 2e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EIM83603.1 - 4.3e-44 146.8 35.0 4.3e-09 35.8 0.0 11.9 12 0 0 12 12 12 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EIM83603.1 - 1.5e-12 47.5 3.2 8e-06 25.4 0.0 5.3 2 1 3 5 5 5 3 PQQ-like domain NACHT PF05729.7 EIM83603.1 - 1.5e-09 37.7 0.4 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 EIM83603.1 - 1.4e-08 34.1 3.8 2.3 7.9 0.0 8.2 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EIM83603.1 - 3.5e-08 33.6 0.1 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain eIF2A PF08662.6 EIM83603.1 - 1.6e-07 31.2 0.1 0.05 13.2 0.0 4.6 4 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIM83603.1 - 8.3e-06 24.2 0.3 0.29 9.2 0.0 4.6 6 0 0 6 6 6 2 Nucleoporin Nup120/160 AAA_22 PF13401.1 EIM83603.1 - 7.3e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Nbas_N PF15492.1 EIM83603.1 - 0.00016 20.9 0.9 1.3 8.0 0.0 5.1 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIM83603.1 - 0.00033 19.5 0.1 0.88 8.2 0.0 3.3 4 0 0 4 4 4 2 Nup133 N terminal like AAA PF00004.24 EIM83603.1 - 0.00038 20.6 0.0 0.0013 18.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIM83603.1 - 0.0021 16.9 0.0 0.005 15.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EIM83603.1 - 0.0045 17.8 0.0 0.014 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIM83603.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIM83603.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EIM83603.1 - 0.035 14.4 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIM83603.1 - 0.038 12.7 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Torsin PF06309.6 EIM83603.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 EIM83603.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM83603.1 - 0.1 12.3 0.0 0.38 10.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EIM83603.1 - 0.12 11.4 0.0 8.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EIM83603.1 - 0.15 11.7 0.1 0.59 9.8 0.0 2.0 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.22 EIM83603.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PQQ_3 PF13570.1 EIM83603.1 - 2.7 8.3 9.0 17 5.8 0.1 5.6 5 1 0 5 5 3 0 PQQ-like domain PUF PF00806.14 EIM83604.1 - 2.1e-28 96.1 0.1 1.5e-07 30.5 0.0 6.6 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat ISN1 PF06437.6 EIM83604.1 - 0.15 10.7 0.1 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Pyridox_oxase_2 PF12766.2 EIM83605.1 - 6.2e-22 77.7 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase tRNA-synt_His PF13393.1 EIM83606.1 - 4.4e-41 140.9 0.1 2.9e-36 125.1 0.0 2.6 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EIM83606.1 - 5.1e-18 65.2 0.0 9.7e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIM83606.1 - 3.7e-11 42.7 0.1 7.1e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.14 EIM83606.1 - 0.042 14.2 4.3 0.19 12.1 3.0 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_2 PF00152.15 EIM83606.1 - 0.085 11.6 0.0 5.3 5.7 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EIM83606.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) Peptidase_C48 PF02902.14 EIM83607.1 - 1.7e-21 76.8 0.0 6.6e-21 74.9 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MT PF12777.2 EIM83607.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor CDP-OH_P_transf PF01066.16 EIM83608.1 - 6.7e-17 61.6 0.3 6.7e-17 61.6 0.2 2.6 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF2235 PF09994.4 EIM83609.1 - 6.3e-75 252.0 0.2 8.2e-75 251.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIM83609.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2_4 PF13894.1 EIM83611.1 - 3.1e-06 27.1 1.1 0.095 13.0 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM83611.1 - 0.0021 18.2 4.6 0.03 14.6 2.3 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM83611.1 - 0.0054 16.9 6.1 0.011 15.9 0.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain DUF1677 PF07911.8 EIM83611.1 - 0.28 11.3 2.3 1.6 8.9 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) DAO PF01266.19 EIM83613.1 - 1.6e-43 148.9 0.0 2.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM83613.1 - 0.00036 20.6 0.0 0.012 15.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM83613.1 - 0.0012 18.7 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM83613.1 - 0.011 15.5 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM83613.1 - 0.024 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EIM83613.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIM83613.1 - 0.033 13.2 0.1 0.12 11.3 0.1 1.8 1 1 0 1 1 1 0 FAD binding domain Bot1p PF12298.3 EIM83614.1 - 1.2e-22 80.7 1.4 1.8e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Methyltransf_16 PF10294.4 EIM83615.1 - 5.3e-16 58.5 0.0 8.3e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM83615.1 - 0.0094 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM83615.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EIM83615.1 - 0.053 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EIM83615.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIM83616.1 - 2.4e-09 37.5 0.0 7e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM83616.1 - 1.8e-08 34.2 0.0 4.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM83616.1 - 5.9e-07 29.7 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM83616.1 - 2.4e-06 28.1 0.0 6.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM83616.1 - 3.5e-05 24.2 0.6 0.0021 18.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM83616.1 - 0.00027 20.1 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EIM83616.1 - 0.0015 17.6 0.0 0.0045 16.0 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EIM83616.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SF3b10 PF07189.6 EIM83617.1 - 2.1e-31 107.5 0.0 2.6e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF727 PF05303.7 EIM83618.1 - 0.0007 19.3 0.1 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) DHquinase_II PF01220.14 EIM83618.1 - 0.031 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Dehydroquinase class II Sas10_Utp3 PF04000.10 EIM83619.1 - 1.2e-16 60.6 0.0 2.2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family LRR_6 PF13516.1 EIM83620.1 - 1.5e-06 27.6 3.6 1.4 9.1 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 EIM83620.1 - 9.4e-06 25.2 0.0 2.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EIM83620.1 - 0.00019 21.0 6.2 3.7 7.9 0.1 6.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 EIM83620.1 - 0.018 14.8 6.7 10 5.9 0.0 4.7 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EIM83620.1 - 0.057 13.0 3.5 2.5 7.7 0.0 4.6 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIM83620.1 - 0.097 12.9 9.7 4 8.0 0.2 5.8 6 0 0 6 6 6 0 Leucine rich repeat YABBY PF04690.8 EIM83621.1 - 8.5e-08 32.6 0.0 1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.5 EIM83621.1 - 0.00032 21.0 0.5 0.00041 20.6 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EIM83621.1 - 0.0016 18.6 0.2 0.0016 18.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EIM83621.1 - 0.014 15.6 1.1 0.018 15.2 0.8 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box Sec1 PF00995.18 EIM83622.1 - 3.3e-115 385.8 0.0 4e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Flavi_NS5 PF00972.15 EIM83622.1 - 0.19 9.5 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase cNMP_binding PF00027.24 EIM83623.1 - 6.8e-41 137.9 0.0 8.9e-19 67.0 0.0 4.7 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EIM83623.1 - 4.7e-17 62.6 9.5 1.7e-12 47.6 1.5 3.6 4 0 0 4 4 4 2 Patatin-like phospholipase Chitin_synth_1 PF01644.12 EIM83624.1 - 4.3e-76 254.2 0.2 6.1e-76 253.7 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIM83624.1 - 1.7e-24 86.0 0.0 2.6e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EIM83624.1 - 2.8e-23 81.3 0.0 6.6e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EIM83624.1 - 3.6e-08 33.3 0.1 3.6e-08 33.3 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM83624.1 - 3.6e-08 33.4 0.0 2.2e-07 30.8 0.0 2.0 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 EIM83626.1 - 1.9e-37 128.8 0.0 2.3e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83626.1 - 1.5e-13 50.4 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM83626.1 - 4.5e-05 23.3 0.0 0.0022 17.7 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIM83626.1 - 0.014 14.2 0.1 0.019 13.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3793 PF12672.2 EIM83626.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Kdo PF06293.9 EIM83626.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF917 PF06032.7 EIM83628.1 - 8.2e-16 57.4 0.0 1.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EIM83628.1 - 0.00032 19.9 0.1 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Aldedh PF00171.17 EIM83629.1 - 1.3e-40 139.1 0.0 1.2e-20 73.3 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family F-box-like PF12937.2 EIM83633.1 - 1.2e-08 34.5 0.8 1.2e-08 34.5 0.6 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 EIM83633.1 - 0.047 13.3 2.5 7.1 6.4 0.0 3.3 3 0 0 3 3 3 0 F-box domain Tub_2 PF04525.7 EIM83634.1 - 0.073 12.4 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 Tubby C 2 SNF2_N PF00176.18 EIM83636.1 - 5e-24 84.6 0.4 5.4e-23 81.2 0.3 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM83636.1 - 0.0014 18.4 0.1 0.0072 16.1 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Pox_F11 PF04943.7 EIM83636.1 - 0.042 12.7 0.2 0.077 11.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus F11 protein Helicase_C_4 PF13871.1 EIM83636.1 - 0.044 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like Ribonucleas_3_3 PF14622.1 EIM83639.1 - 0.029 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM83639.1 - 0.055 13.9 0.0 0.082 13.3 0.0 1.3 1 1 0 1 1 1 0 Ribonuclease III domain Joubert PF15392.1 EIM83641.1 - 0.1 11.8 0.3 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated Exo_endo_phos_2 PF14529.1 EIM83642.1 - 0.073 12.6 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Nop14 PF04147.7 EIM83643.1 - 0.013 13.4 11.5 0.017 13.0 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIM83643.1 - 0.031 12.3 1.1 0.037 12.0 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EIM83643.1 - 0.1 11.8 8.3 0.14 11.4 5.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 EIM83643.1 - 0.21 10.8 10.7 0.28 10.4 7.4 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EIM83643.1 - 0.64 8.4 14.0 0.84 8.0 9.7 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EIM83643.1 - 3.7 6.7 9.0 5.4 6.1 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EIM83643.1 - 5.6 5.5 13.7 8.2 5.0 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF917 PF06032.7 EIM83645.1 - 6.7e-13 47.9 0.0 1.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) CENP-I PF07778.6 EIM83645.1 - 0.17 10.0 0.3 0.24 9.5 0.2 1.1 1 0 0 1 1 1 0 Mis6 HAUS5 PF14817.1 EIM83646.1 - 0.062 11.8 0.1 0.077 11.5 0.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1052 PF06319.7 EIM83646.1 - 0.074 12.3 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) AAA PF00004.24 EIM83650.1 - 6.2e-16 58.7 0.0 1.3e-14 54.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM83650.1 - 9.9e-05 22.4 0.0 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM83650.1 - 0.0001 22.3 0.1 0.00021 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIM83650.1 - 0.00019 22.2 0.0 0.00044 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM83650.1 - 0.00052 19.8 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM83650.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIM83650.1 - 0.0022 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EIM83650.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIM83650.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EIM83650.1 - 0.017 14.8 0.1 0.058 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIM83650.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EIM83650.1 - 0.03 14.2 0.0 0.072 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EIM83650.1 - 0.031 13.9 0.1 0.074 12.6 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_11 PF13086.1 EIM83650.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIM83650.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 EIM83650.1 - 0.064 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EIM83650.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 EIM83650.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EIM83650.1 - 0.078 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus cobW PF02492.14 EIM83650.1 - 0.095 12.1 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EIM83650.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EIM83650.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter zf-RING_2 PF13639.1 EIM83651.1 - 0.015 15.1 11.4 0.024 14.4 7.9 1.3 1 0 0 1 1 1 0 Ring finger domain U79_P34 PF03064.11 EIM83651.1 - 0.019 14.4 2.3 0.025 14.0 1.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2828 PF11443.3 EIM83651.1 - 0.021 13.0 3.0 0.024 12.8 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RINGv PF12906.2 EIM83651.1 - 4.2 7.4 12.6 5.9 7.0 7.9 1.9 1 1 1 2 2 2 0 RING-variant domain Tet_JBP PF12851.2 EIM83652.1 - 5.6e-06 25.7 0.0 7.6e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily TPR_6 PF13174.1 EIM83652.1 - 0.062 13.7 0.1 6.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CPSF_A PF03178.10 EIM83655.1 - 0.075 12.1 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 CPSF A subunit region CBFD_NFYB_HMF PF00808.18 EIM83656.1 - 2.4e-12 46.7 1.8 2.4e-12 46.7 1.3 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIM83656.1 - 2.2e-07 30.9 0.6 2.9e-07 30.5 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EIM83656.1 - 0.025 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated G-alpha PF00503.15 EIM83658.1 - 7.2e-35 120.4 0.4 1.4e-34 119.4 0.3 1.5 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM83658.1 - 3.6e-06 26.3 2.2 9.6e-06 24.9 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Pex16 PF08610.5 EIM83660.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Glyco_trans_2_3 PF13632.1 EIM83661.1 - 5e-05 23.0 0.1 5e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Dysbindin PF04440.11 EIM83662.1 - 0.084 12.6 2.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) Fez1 PF06818.10 EIM83662.1 - 1.4 8.9 7.8 0.95 9.4 3.6 2.0 1 1 0 2 2 2 0 Fez1 TPP_enzyme_M PF00205.17 EIM83663.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain zf-RVT PF13966.1 EIM83670.1 - 3.5e-05 24.0 3.8 0.00014 22.0 2.6 2.0 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EIM83670.1 - 0.00072 19.9 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 RNase H F-box-like PF12937.2 EIM83672.1 - 0.00017 21.2 0.8 0.00053 19.6 0.5 1.9 1 0 0 1 1 1 1 F-box-like Rad60-SLD PF11976.3 EIM83672.1 - 0.075 12.7 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like RNase_H2-Ydr279 PF09468.5 EIM83673.1 - 0.68 9.0 8.0 0.068 12.3 2.0 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) TT_ORF1 PF02956.9 EIM83673.1 - 8.5 4.6 15.0 11 4.3 10.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 Gti1_Pac2 PF09729.4 EIM83674.1 - 1.1e-40 139.2 0.8 1.6e-34 119.1 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Mannitol_dh_C PF08125.8 EIM83675.1 - 2.8e-08 33.2 0.0 3.1e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Clr2 PF10383.4 EIM83676.1 - 0.0014 18.6 0.0 0.0048 16.8 0.0 2.0 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 CBM_1 PF00734.13 EIM83677.1 - 5.8e-12 45.0 12.6 1.5e-11 43.7 8.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 EIM83677.1 - 4.7e-08 31.7 24.5 1.6 8.8 0.1 9.1 9 0 0 9 9 9 5 BNR/Asp-box repeat SpoOE-like PF09388.5 EIM83680.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein ORC6 PF05460.8 EIM83680.1 - 0.33 10.0 2.9 0.36 9.8 2.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) UBN2_2 PF14227.1 EIM83681.1 - 1.1e-11 44.3 0.4 2e-11 43.5 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM83681.1 - 3e-07 30.2 0.4 1.1e-06 28.3 0.3 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EIM83681.1 - 0.0074 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 EIM83681.1 - 0.081 12.3 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EIM83681.1 - 0.081 12.4 0.2 0.22 11.0 0.1 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.1 EIM83683.1 - 3e-12 46.4 0.0 4.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIM83683.1 - 1e-05 25.0 0.1 1e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIM83683.1 - 0.0001 22.1 0.0 0.00037 20.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIM83683.1 - 0.00053 20.7 1.4 0.075 13.8 0.2 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.17 EIM83683.1 - 0.0036 17.1 0.0 0.66 9.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_Tnp_1 PF01527.15 EIM83683.1 - 0.0038 17.1 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIM83683.1 - 0.0072 16.4 0.1 0.024 14.8 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_19 PF12844.2 EIM83683.1 - 0.024 14.6 0.2 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MerR_1 PF13411.1 EIM83683.1 - 0.037 13.8 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein Terminase_5 PF06056.7 EIM83683.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MerR PF00376.18 EIM83683.1 - 0.083 12.4 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 MerR family regulatory protein zf-CCHC PF00098.18 EIM83686.1 - 3.1 7.8 10.0 0.11 12.4 2.8 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 EIM83687.1 - 9.2e-10 38.0 5.7 1.4e-09 37.4 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIM83687.1 - 1.4e-07 31.0 4.0 2.3e-07 30.3 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM83687.1 - 5.1e-07 29.4 7.8 8.8e-07 28.6 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM83687.1 - 5.5e-06 26.2 8.0 1.1e-05 25.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM83687.1 - 8e-05 22.2 7.6 0.00014 21.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM83687.1 - 0.00015 21.4 3.2 0.00039 20.0 2.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIM83687.1 - 0.0018 17.9 0.4 0.0034 17.1 0.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EIM83687.1 - 0.0073 16.1 7.4 0.021 14.7 5.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EIM83687.1 - 0.013 15.0 6.2 0.024 14.1 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EIM83687.1 - 0.028 13.9 4.7 0.057 12.9 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EIM83687.1 - 0.12 12.5 4.8 0.22 11.6 3.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1272 PF06906.6 EIM83687.1 - 0.12 12.2 3.5 0.24 11.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2HC_2 PF13913.1 EIM83687.1 - 0.14 11.8 2.2 0.26 10.9 1.1 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type p450 PF00067.17 EIM83691.1 - 1.9e-43 148.6 0.0 2.5e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Suc_Fer-like PF06999.7 EIM83692.1 - 2.1e-22 80.2 0.0 2.1e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like TIM PF00121.13 EIM83693.1 - 1.2e-90 302.8 0.0 1.4e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Pkinase PF00069.20 EIM83694.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83694.1 - 5.6e-05 22.3 0.0 0.00013 21.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM83694.1 - 0.0037 16.3 0.3 0.0083 15.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GlnE PF03710.10 EIM83694.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase APH PF01636.18 EIM83694.1 - 0.067 12.9 0.3 0.28 10.8 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mo25 PF08569.6 EIM83695.1 - 2.2e-119 398.4 2.5 2.4e-119 398.2 1.7 1.0 1 0 0 1 1 1 1 Mo25-like UME PF08064.8 EIM83695.1 - 0.032 14.1 0.0 5.6 6.9 0.1 2.6 2 0 0 2 2 2 0 UME (NUC010) domain RepA_N PF06970.6 EIM83695.1 - 0.2 11.4 1.9 0.26 11.1 0.3 2.0 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Aldo_ket_red PF00248.16 EIM83696.1 - 3.1e-57 193.5 0.0 3.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EIM83696.1 - 0.027 13.0 0.0 0.066 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) Aldo_ket_red PF00248.16 EIM83697.1 - 2e-53 181.0 0.1 2.4e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EIM83697.1 - 0.032 12.7 0.0 0.25 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) DUF1744 PF08490.7 EIM83698.1 - 2.5e-105 352.3 0.0 4.9e-105 351.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EIM83698.1 - 1.1e-60 205.1 0.1 2e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EIM83698.1 - 4e-18 65.4 0.0 2.5e-17 62.8 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EIM83698.1 - 6.7e-09 35.5 0.3 2.3e-08 33.8 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EIM83698.1 - 0.00075 19.3 0.0 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily Pro-kuma_activ PF09286.6 EIM83699.1 - 2.8e-32 111.7 0.1 7.5e-32 110.3 0.1 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM83699.1 - 4.5e-08 32.5 0.4 4.5e-08 32.5 0.3 2.2 2 0 0 2 2 2 1 Subtilase family p450 PF00067.17 EIM83701.1 - 7.7e-59 199.4 0.0 1.1e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM83702.1 - 1.2e-27 96.5 0.0 1.9e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIM83703.1 - 3.8e-64 216.9 0.0 5e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GLE1 PF07817.8 EIM83704.1 - 2.1e-28 98.9 0.0 2.1e-28 98.9 0.0 2.7 2 2 0 2 2 2 1 GLE1-like protein CAF-1_p150 PF11600.3 EIM83704.1 - 0.22 10.8 56.7 0.42 9.9 39.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SDH_alpha PF03313.10 EIM83704.1 - 2.9 6.8 7.6 5.5 5.9 5.3 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain RNA_pol_Rpb5_C PF01191.14 EIM83705.1 - 3.5e-33 113.0 0.4 8.2e-33 111.8 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EIM83705.1 - 7.5e-28 96.7 0.3 1.6e-27 95.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EIM83705.1 - 0.0041 16.9 0.0 0.0068 16.2 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease F-box-like PF12937.2 EIM83706.1 - 1.4e-08 34.3 3.1 4.2e-08 32.7 0.9 2.8 3 0 0 3 3 3 1 F-box-like PAGK PF15284.1 EIM83706.1 - 0.14 11.9 0.2 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor Transp_cyt_pur PF02133.10 EIM83707.1 - 5.5e-88 295.4 29.7 7.5e-82 275.2 16.2 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EIM83708.1 - 1.2e-104 349.6 0.8 1.8e-104 349.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EIM83708.1 - 3e-36 125.0 1.1 3e-36 125.0 0.8 2.6 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM83708.1 - 3.3e-27 95.1 0.1 2.4e-26 92.3 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EIM83708.1 - 0.014 14.3 0.4 0.45 9.4 0.0 2.3 2 0 0 2 2 2 0 StbA protein Polysacc_lyase PF14099.1 EIM83709.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 2 0 0 2 2 2 0 Polysaccharide lyase Polysacc_lyase PF14099.1 EIM83710.1 - 0.01 15.5 0.6 0.028 14.0 0.5 2.0 1 1 0 1 1 1 0 Polysaccharide lyase Tmemb_18A PF09771.4 EIM83710.1 - 0.06 13.3 0.0 4 7.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 Beta-lactamase PF00144.19 EIM83711.1 - 5.4e-36 124.2 0.0 9.6e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EIM83711.1 - 0.022 14.5 0.3 0.16 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3471) ADH_zinc_N PF00107.21 EIM83712.1 - 1.6e-15 56.7 0.1 3e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM83712.1 - 7.4e-06 25.6 0.1 2.1e-05 24.2 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM83712.1 - 1.1e-05 26.3 0.0 5.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM83713.1 - 3e-15 55.9 0.0 4.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM83713.1 - 2.7e-06 27.0 0.1 8.3e-06 25.5 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM83713.1 - 1e-05 26.4 0.0 4.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.1 EIM83714.1 - 2e-07 30.7 10.2 3.2e-07 30.0 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM83714.1 - 4.1e-07 29.9 9.6 8.1e-07 28.9 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM83714.1 - 1.3e-06 27.9 9.3 2.5e-06 27.1 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM83714.1 - 1.8e-06 27.4 6.4 4.9e-06 26.0 4.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM83714.1 - 1e-05 25.3 9.1 2.3e-05 24.1 6.4 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIM83714.1 - 1.3e-05 24.7 11.3 2.7e-05 23.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM83714.1 - 4.7e-05 23.0 4.8 0.00017 21.2 2.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIM83714.1 - 0.00076 19.0 10.1 0.0012 18.3 7.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 EIM83714.1 - 0.016 15.1 8.8 0.016 15.1 6.1 2.0 2 1 1 3 3 3 0 FYVE zinc finger DUF3401 PF11881.3 EIM83714.1 - 0.021 14.2 0.1 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3401) Pellino PF04710.9 EIM83714.1 - 0.15 10.7 1.1 0.2 10.2 0.7 1.1 1 0 0 1 1 1 0 Pellino zf-Apc11 PF12861.2 EIM83714.1 - 0.19 11.6 3.3 0.33 10.8 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIM83714.1 - 0.24 11.5 6.9 0.45 10.6 4.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Rtf2 PF04641.7 EIM83714.1 - 0.63 9.2 3.4 0.23 10.6 0.4 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Vps39_2 PF10367.4 EIM83714.1 - 6.7 6.9 8.6 11 6.2 3.0 2.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Ribosomal_L24e PF01246.15 EIM83715.1 - 4e-30 103.4 0.3 4e-30 103.4 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 EIM83715.1 - 0.58 10.1 5.1 0.8 9.7 3.5 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family MFS_1 PF07690.11 EIM83716.1 - 1.8e-29 102.6 27.4 1.8e-29 102.6 19.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM83716.1 - 1.1 9.0 9.1 0.053 13.3 0.9 2.9 3 0 0 3 3 3 0 MFS_1 like family Pkinase PF00069.20 EIM83718.1 - 9.7e-74 247.7 0.0 3e-73 246.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83718.1 - 3e-40 137.9 0.0 4.7e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM83718.1 - 1.7e-11 43.6 0.0 2.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM83718.1 - 0.035 13.1 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3328 PF11807.3 EIM83719.1 - 1.6e-23 83.5 0.0 2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 EIM83720.1 - 0.00089 19.0 1.7 0.00089 19.0 1.2 1.9 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1349 PF07081.6 EIM83721.1 - 3.2e-32 111.3 0.1 3.7e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GFA PF04828.9 EIM83722.1 - 2.1e-08 33.9 24.8 0.0099 15.8 5.4 5.3 4 1 0 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme Inh PF02974.9 EIM83722.1 - 0.03 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Protease inhibitor Inh Synaptobrevin PF00957.16 EIM83723.1 - 1.1e-27 95.4 5.7 1.3e-27 95.1 4.0 1.1 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 EIM83723.1 - 0.068 12.8 0.3 0.089 12.4 0.2 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3294 PF07957.6 EIM83723.1 - 0.084 12.3 0.6 0.098 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Fzo_mitofusin PF04799.8 EIM83723.1 - 0.19 11.1 1.9 0.13 11.6 0.6 1.3 1 1 0 1 1 1 0 fzo-like conserved region DUF2417 PF10329.4 EIM83725.1 - 0.2 11.0 6.7 0.35 10.2 0.1 2.2 1 1 1 2 2 2 0 Region of unknown function (DUF2417) Synaptobrevin PF00957.16 EIM83727.1 - 2e-30 104.2 0.5 2.9e-30 103.6 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIM83727.1 - 1.9e-21 75.4 0.0 3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.4 EIM83727.1 - 0.11 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Ribosomal_S11 PF00411.14 EIM83728.1 - 2e-41 140.6 0.5 2.5e-41 140.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 HTH_31 PF13560.1 EIM83730.1 - 5.2e-08 32.9 0.0 5.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EIM83730.1 - 7.1e-06 25.9 0.0 7.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EIM83730.1 - 3.6e-05 23.5 0.0 4.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 EIM83730.1 - 0.0075 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIM83730.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2316 PF10078.4 EIM83730.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Hydantoinase_B PF02538.9 EIM83732.1 - 5.5e-176 585.8 0.1 2.6e-89 299.8 0.1 3.0 2 1 0 2 2 2 2 Hydantoinase B/oxoprolinase zf-UBR PF02207.15 EIM83733.1 - 9.2e-10 38.1 12.2 9.2e-10 38.1 8.5 3.4 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EIM83733.1 - 8.3e-07 28.6 3.2 8.3e-07 28.6 2.2 3.7 5 0 0 5 5 5 1 PHD-finger Aldedh PF00171.17 EIM83734.1 - 7.3e-84 281.7 0.0 8.6e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.1 EIM83734.1 - 0.023 14.2 0.0 0.63 9.6 0.0 2.7 2 0 0 2 2 2 0 ACT domain PIRT PF15099.1 EIM83735.1 - 0.35 10.0 3.2 0.3 10.3 0.7 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family MAP65_ASE1 PF03999.7 EIM83736.1 - 1.7e-66 225.1 2.4 6.3e-62 210.0 0.4 2.1 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) FH2 PF02181.18 EIM83736.1 - 0.0074 15.2 2.2 0.011 14.7 0.5 1.9 1 1 1 2 2 2 1 Formin Homology 2 Domain Herpes_U5 PF05999.6 EIM83736.1 - 0.062 11.8 1.0 0.098 11.2 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family FNIP_C PF14638.1 EIM83737.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus PrgI PF12666.2 EIM83738.1 - 8.3 6.6 6.8 33 4.7 4.7 1.9 1 1 0 1 1 1 0 PrgI family protein Lactonase PF10282.4 EIM83739.1 - 1.7e-35 122.7 0.0 2.1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller BACON PF13004.2 EIM83739.1 - 0.023 14.9 0.0 0.075 13.2 0.0 2.0 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal DUF1586 PF07625.6 EIM83739.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) Acetyltransf_1 PF00583.19 EIM83740.1 - 6.5e-11 42.1 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM83740.1 - 3.2e-10 40.0 0.1 4.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM83740.1 - 0.0033 17.2 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM83740.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIM83740.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEP PF00610.16 EIM83744.1 - 0.056 13.1 0.1 25 4.7 0.0 3.4 3 1 1 4 4 4 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FSH1 PF03959.8 EIM83744.1 - 1 8.7 3.4 66 2.8 0.1 3.3 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Proteasome PF00227.21 EIM83745.1 - 1.1e-35 122.6 0.0 1.5e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 EIM83746.1 - 5.9e-43 140.9 12.6 2.6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIM83746.1 - 3.1e-38 129.7 3.7 5.3e-21 74.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIM83746.1 - 2.8e-34 116.4 11.1 2.5e-16 59.0 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIM83746.1 - 1.1e-31 105.8 7.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIM83746.1 - 2.4e-28 96.1 7.3 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIM83746.1 - 7.2e-15 54.6 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIM83746.1 - 2.5e-10 40.0 0.7 6.6e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIM83746.1 - 4.8e-09 36.2 0.0 0.00049 20.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EIM83746.1 - 1.5e-08 34.1 0.1 0.0085 15.6 0.0 3.8 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EIM83746.1 - 2e-06 27.6 1.3 2.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 EIM83746.1 - 0.00033 20.1 1.2 0.00037 19.9 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 EIM83746.1 - 0.00056 19.5 0.1 0.036 13.6 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein EF-hand_like PF09279.6 EIM83746.1 - 0.0006 19.7 0.4 0.011 15.7 0.0 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 EIM83746.1 - 0.0023 17.6 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.11 EIM83746.1 - 0.019 14.6 0.1 3.8 7.3 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein Tenui_NCP PF04876.7 EIM83746.1 - 0.039 13.5 0.1 0.78 9.2 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EIM83746.1 - 0.048 13.6 1.2 8.9 6.3 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 EIM83746.1 - 0.056 13.7 0.7 13 6.2 0.0 2.4 1 1 0 2 2 2 0 Toprim-like MotA_activ PF09114.5 EIM83746.1 - 0.083 12.6 0.2 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 EIM83746.1 - 0.11 12.0 0.1 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) JSRP PF15312.1 EIM83747.1 - 2.4 8.2 4.3 0.81 9.6 0.1 2.0 2 1 0 2 2 2 0 Junctional sarcoplasmic reticulum protein WH1 PF00568.18 EIM83748.1 - 4.8e-21 74.5 0.0 6.4e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EIM83748.1 - 0.0002 21.6 0.2 0.00052 20.3 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EIM83748.1 - 0.011 15.3 0.2 0.011 15.3 0.1 2.2 2 0 0 2 2 2 0 WH2 motif GFA PF04828.9 EIM83749.1 - 6.7e-09 35.5 1.3 6.7e-09 35.5 0.9 3.2 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme FAD_oxidored PF12831.2 EIM83749.1 - 0.073 12.1 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase PAM2 PF07145.10 EIM83750.1 - 0.067 12.7 0.4 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Cyt-b5 PF00173.23 EIM83751.1 - 2e-14 53.1 0.0 4.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EIM83751.1 - 2.9e-14 53.1 25.4 4.8e-14 52.4 17.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_hydro_71 PF03659.9 EIM83752.1 - 3.1e-76 256.3 15.4 5e-61 206.2 6.8 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 TRI5 PF06330.6 EIM83754.1 - 0.0051 15.5 0.0 0.0091 14.6 0.0 1.4 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.6 EIM83755.1 - 2.1e-09 36.5 0.0 3.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) Oxidored_FMN PF00724.15 EIM83756.1 - 1e-06 27.9 0.0 0.026 13.5 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.16 EIM83757.1 - 1.5e-48 165.0 0.0 1.9e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 EIM83757.1 - 0.097 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease FHA PF00498.21 EIM83759.1 - 6.3e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIM83759.1 - 3.3e-09 36.4 10.5 4.9e-09 35.8 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM83759.1 - 1.3e-05 25.1 5.3 2.4e-05 24.3 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIM83759.1 - 4.5e-05 23.0 10.8 7e-05 22.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM83759.1 - 0.00025 20.8 2.8 0.0004 20.1 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIM83759.1 - 0.013 15.2 9.3 0.021 14.5 6.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EIM83759.1 - 0.014 15.1 5.5 0.024 14.3 3.8 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EIM83759.1 - 0.014 15.0 7.1 0.023 14.3 4.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM83759.1 - 0.023 14.7 11.5 0.036 14.0 8.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAP1 PF08601.5 EIM83759.1 - 4.2 6.9 9.6 6.2 6.4 6.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Acetyltransf_1 PF00583.19 EIM83760.1 - 5.3e-06 26.3 0.2 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM83760.1 - 9.1e-06 25.5 0.1 0.00066 19.5 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM83760.1 - 0.00012 22.1 0.1 0.00025 21.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM83760.1 - 0.0015 18.6 0.4 0.0025 17.9 0.2 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM83760.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MOZ_SAS PF01853.13 EIM83760.1 - 0.043 13.0 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Peptidase_C14 PF00656.17 EIM83761.1 - 2e-16 60.4 0.0 3.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Aldo_ket_red PF00248.16 EIM83762.1 - 2.4e-51 174.2 0.0 3.2e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Beach PF02138.13 EIM83763.1 - 9.6e-99 330.1 0.0 1.6e-98 329.4 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 EIM83763.1 - 1.7e-10 41.3 0.3 5e-10 39.8 0.2 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EIM83763.1 - 2e-08 34.0 0.0 5.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EIM83763.1 - 3.8e-06 26.5 14.0 0.00012 21.7 0.8 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_2 PF02210.19 EIM83763.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain DUF3926 PF13080.1 EIM83764.1 - 0.041 13.4 0.3 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Peptidase_S24 PF00717.18 EIM83764.1 - 0.044 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase S24-like p47_phox_C PF08944.6 EIM83765.1 - 0.012 15.7 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Transposase_21 PF02992.9 EIM83766.1 - 1.4e-13 50.4 0.0 2.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIM83766.1 - 0.00017 20.9 0.2 0.00033 20.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) MyTH4 PF00784.12 EIM83767.1 - 0.17 11.8 1.5 3.2 7.7 0.0 2.9 3 0 0 3 3 3 0 MyTH4 domain Lactamase_B_4 PF13691.1 EIM83770.1 - 0.00055 19.3 0.3 2.2 7.8 0.0 3.3 3 0 0 3 3 3 2 tRNase Z endonuclease ACP PF06857.6 EIM83770.1 - 0.024 14.5 0.0 76 3.3 0.0 3.8 4 0 0 4 4 4 0 Malonate decarboxylase delta subunit (MdcD) GIDA_assoc_3 PF13932.1 EIM83770.1 - 0.16 12.0 0.4 13 5.9 0.0 3.4 4 0 0 4 4 4 0 GidA associated domain 3 Methyltransf_11 PF08241.7 EIM83771.1 - 1.8e-18 66.8 0.0 2.8e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM83771.1 - 8.3e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM83771.1 - 2.5e-11 44.1 0.0 3.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM83771.1 - 4.4e-11 42.5 0.0 6.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM83771.1 - 9e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM83771.1 - 1.3e-08 34.6 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM83771.1 - 1.6e-06 27.3 0.0 2.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIM83771.1 - 2.4e-05 24.3 0.0 5.8e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM83771.1 - 0.066 12.5 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EIM83771.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 EIM83771.1 - 0.091 12.3 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase p450 PF00067.17 EIM83773.1 - 2.7e-68 230.6 0.0 3.4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fer2_3 PF13085.1 EIM83774.1 - 5.3e-32 109.9 0.0 8.1e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EIM83774.1 - 1.5e-10 41.2 6.9 1.5e-10 41.2 4.8 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIM83774.1 - 2e-08 34.1 5.3 2e-08 34.1 3.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EIM83774.1 - 3.2e-05 24.2 2.4 3.2e-05 24.2 1.7 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIM83774.1 - 0.00017 21.3 5.6 0.00017 21.3 3.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIM83774.1 - 0.00055 20.2 3.7 0.00055 20.2 2.6 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIM83774.1 - 0.0019 18.4 9.2 0.019 15.2 0.3 3.1 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EIM83774.1 - 0.0071 16.0 1.4 0.0071 16.0 1.0 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EIM83774.1 - 0.21 12.1 6.6 1.2 9.7 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain zf-MYND PF01753.13 EIM83777.1 - 0.012 15.4 1.0 0.023 14.5 0.7 1.5 1 0 0 1 1 1 0 MYND finger Meth_synt_2 PF01717.13 EIM83778.1 - 9.8e-21 74.0 0.0 2.5e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM83778.1 - 1.4e-08 34.4 0.0 0.026 13.7 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain ERM PF00769.14 EIM83780.1 - 0.019 14.5 2.7 0.049 13.1 1.9 1.7 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Profilin PF00235.14 EIM83781.1 - 6.2e-41 139.2 0.6 6.9e-41 139.1 0.4 1.0 1 0 0 1 1 1 1 Profilin Oxidored_FMN PF00724.15 EIM83783.1 - 9.6e-98 327.3 0.0 1.1e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CDH PF02611.10 EIM83783.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Rep_2 PF01719.12 EIM83783.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication protein ORC5_C PF14630.1 EIM83784.1 - 1.4e-43 149.3 0.0 9.6e-43 146.5 0.0 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PAT1 PF09770.4 EIM83787.1 - 5.3 5.1 6.9 7.3 4.6 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ICMT PF04140.9 EIM83788.1 - 4.4e-15 55.6 0.0 6.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM83788.1 - 1e-10 41.6 0.4 6.3e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM83788.1 - 0.00079 18.0 0.1 0.064 11.7 0.0 2.1 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EIM83789.1 - 1e-12 48.0 0.0 1.8e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM83789.1 - 1.8e-11 44.1 0.6 1.1e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM83789.1 - 7.3e-07 28.0 0.6 1.4e-06 27.1 0.4 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0126 PF03458.8 EIM83789.1 - 0.017 14.7 0.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 UPF0126 domain Lipase_GDSL PF00657.17 EIM83790.1 - 6.9e-16 58.7 0.2 8.8e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.27 EIM83791.1 - 5.9e-11 41.8 11.5 0.014 15.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2235 PF09994.4 EIM83792.1 - 5.3e-59 199.8 0.0 8.5e-58 195.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) YvbH_ext PF11724.3 EIM83792.1 - 0.077 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Abhydrolase_2 PF02230.11 EIM83792.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.27 EIM83793.1 - 1.8e-110 357.3 36.8 2.1e-11 43.2 0.0 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM83793.1 - 2.3e-10 39.8 2.3 0.0069 15.1 0.0 5.4 3 2 2 5 5 5 3 Nup133 N terminal like Nup160 PF11715.3 EIM83793.1 - 1.7e-07 29.8 2.7 0.051 11.7 0.0 5.5 3 2 1 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIM83793.1 - 0.00031 20.3 0.9 1.3 8.7 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIM83793.1 - 0.007 16.6 7.7 7.7 6.9 0.2 6.4 4 2 2 6 6 6 1 PQQ-like domain Proteasome_A_N PF10584.4 EIM83793.1 - 0.028 13.7 0.2 15 5.0 0.0 4.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 EIM83793.1 - 0.21 9.7 0.0 5.8 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Hemerythrin PF01814.18 EIM83794.1 - 0.00044 20.4 0.1 0.00044 20.4 0.1 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.18 EIM83795.1 - 0.02 15.0 0.2 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4436 PF14494.1 EIM83796.1 - 3.7e-11 42.8 0.5 6.6e-11 41.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Methyltransf_25 PF13649.1 EIM83797.1 - 3.3e-07 30.5 0.2 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM83797.1 - 0.0007 20.1 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM83797.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1890 PF09001.6 EIM83797.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1890) Methyltransf_11 PF08241.7 EIM83797.1 - 0.091 13.2 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Meth_synt_2 PF01717.13 EIM83799.1 - 1.2e-19 70.4 0.0 3.8e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM83799.1 - 5.3e-09 35.7 0.0 0.0038 16.5 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain zf-MYND PF01753.13 EIM83800.1 - 2.5e-10 40.0 9.6 8.4e-10 38.3 6.7 1.9 1 0 0 1 1 1 1 MYND finger Pil1 PF13805.1 EIM83801.1 - 1.2e-17 63.9 0.3 2.2e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Tropomyosin_1 PF12718.2 EIM83801.1 - 0.011 15.6 1.8 0.018 14.9 1.2 1.2 1 0 0 1 1 1 0 Tropomyosin like IncA PF04156.9 EIM83801.1 - 0.056 13.0 0.5 0.087 12.4 0.4 1.3 1 0 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 EIM83801.1 - 0.21 11.5 2.9 0.41 10.6 2.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ABC_tran_2 PF12848.2 EIM83801.1 - 0.35 10.7 1.6 0.63 9.9 1.1 1.3 1 0 0 1 1 1 0 ABC transporter DUF2730 PF10805.3 EIM83801.1 - 0.99 9.1 2.5 1.8 8.3 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1759 PF03564.10 EIM83801.1 - 1.5 8.5 3.6 1.1 9.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Oxidored_FMN PF00724.15 EIM83802.1 - 1.6e-69 234.4 0.0 2.5e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Meth_synt_2 PF01717.13 EIM83803.1 - 2.5e-15 56.2 0.0 1.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM83803.1 - 2.9e-08 33.3 0.0 0.002 17.4 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF605 PF04652.11 EIM83804.1 - 0.77 9.0 22.2 1 8.6 15.4 1.2 1 0 0 1 1 1 0 Vta1 like Phytase-like PF13449.1 EIM83805.1 - 1.2e-17 64.1 3.2 3.2e-16 59.5 2.2 2.7 1 1 0 1 1 1 1 Esterase-like activity of phytase MFS_1 PF07690.11 EIM83806.1 - 9.8e-28 96.8 21.6 9.8e-28 96.8 15.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.13 EIM83806.1 - 0.021 13.3 0.1 0.021 13.3 0.1 1.6 2 0 0 2 2 2 0 Reduced folate carrier ATG22 PF11700.3 EIM83806.1 - 0.043 12.2 12.0 0.024 13.1 4.8 3.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like GMC_oxred_N PF00732.14 EIM83807.1 - 2.2e-68 230.6 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM83807.1 - 5.4e-34 117.5 0.0 9.2e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM83807.1 - 0.0044 15.9 0.8 0.65 8.8 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM83807.1 - 0.0058 15.6 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM83807.1 - 0.0084 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM83807.1 - 0.022 13.6 0.3 0.2 10.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain PTR2 PF00854.16 EIM83808.1 - 3.2e-43 147.9 13.3 4.6e-43 147.4 7.5 2.3 1 1 0 1 1 1 1 POT family Glyco_hydro_cc PF11790.3 EIM83809.1 - 1.4e-38 132.7 0.8 1.6e-38 132.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.17 EIM83810.1 - 3.4e-56 186.7 0.0 3.3e-15 55.4 0.0 6.6 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM83810.1 - 2.2e-42 142.8 0.0 1.4e-09 37.8 0.0 6.7 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM83810.1 - 4.7e-12 45.5 0.0 0.83 9.5 0.0 6.2 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.14 EIM83811.1 - 6.3e-61 206.1 0.6 1e-60 205.3 0.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM83811.1 - 6.8e-34 117.2 0.8 1.2e-33 116.4 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM83811.1 - 1.2e-05 24.4 3.0 0.00011 21.2 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM83811.1 - 6.8e-05 21.8 4.2 0.032 13.0 1.1 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EIM83811.1 - 0.00083 19.2 1.7 0.032 14.1 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM83811.1 - 0.0017 17.3 0.2 0.0026 16.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIM83811.1 - 0.0024 17.0 0.8 0.0061 15.6 0.6 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIM83811.1 - 0.0039 17.1 2.8 0.0075 16.2 1.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM83811.1 - 0.035 12.5 3.9 2 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIM83811.1 - 0.061 13.3 2.4 2.3 8.2 0.6 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 EIM83812.1 - 2.4e-52 177.5 0.1 4.3e-52 176.6 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EIM83812.1 - 0.026 13.0 0.1 0.056 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) DAP_epimerase PF01678.14 EIM83812.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase Aldo_ket_red PF00248.16 EIM83814.1 - 2.2e-55 187.5 0.1 2.5e-55 187.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EIM83815.1 - 6.2e-44 150.2 0.0 1.3e-43 149.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EIM83816.1 - 1.8e-23 83.2 1.5 1e-22 80.8 1.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM83816.1 - 5.8e-13 49.1 0.0 8.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM83816.1 - 6.5e-08 32.4 0.2 1e-07 31.8 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM83816.1 - 0.00016 21.7 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIM83816.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM83816.1 - 0.036 13.4 0.2 0.2 11.0 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM83816.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein APH PF01636.18 EIM83817.1 - 9.1e-10 38.6 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 EIM83817.1 - 0.028 14.2 7.2 0.059 13.2 5.0 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger EamA PF00892.15 EIM83818.1 - 2.3e-22 79.3 29.3 5.5e-12 45.8 5.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIM83818.1 - 8.7e-05 22.6 31.3 0.00063 19.9 5.1 3.3 1 1 3 4 4 4 2 Multidrug resistance efflux transporter SKI PF01202.17 EIM83820.1 - 1.8e-08 34.3 0.0 1.9e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.1 EIM83820.1 - 3e-07 31.2 0.0 4.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM83820.1 - 2.3e-05 24.2 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIM83820.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EIM83820.1 - 0.0044 16.9 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 EIM83820.1 - 0.017 15.1 0.5 0.024 14.6 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EIM83820.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 EIM83820.1 - 0.035 13.7 0.2 0.31 10.6 0.2 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EIM83820.1 - 0.038 13.0 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EIM83820.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EIM83820.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EIM83820.1 - 0.09 13.0 0.5 0.23 11.7 0.3 1.6 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 EIM83820.1 - 0.16 11.5 0.5 8.6 5.9 0.0 2.8 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein SNARE PF05739.14 EIM83821.1 - 4e-05 23.2 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 SNARE domain tRNA_anti-like PF12869.2 EIM83821.1 - 0.03 13.8 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like BRI3BP PF14965.1 EIM83821.1 - 0.22 10.9 0.9 1.3 8.3 0.1 1.9 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Rhodanese PF00581.15 EIM83822.1 - 2.5e-18 66.4 1.2 8.6e-07 29.3 0.0 3.2 3 0 0 3 3 3 3 Rhodanese-like domain DUF4267 PF14087.1 EIM83823.1 - 3.6e-29 100.6 5.0 4.2e-29 100.4 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Ion_trans_2 PF07885.11 EIM83825.1 - 1.2e-25 88.9 33.0 3.3e-14 52.3 6.9 3.2 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.21 EIM83825.1 - 9.1e-05 22.2 0.3 0.6 9.8 0.4 2.9 2 0 0 2 2 2 2 Ligand-gated ion channel DUF3087 PF11286.3 EIM83825.1 - 0.026 13.7 0.5 0.069 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) ATG13 PF10033.4 EIM83826.1 - 2e-34 119.0 0.1 3.4e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF1176 PF06674.6 EIM83830.1 - 0.026 13.6 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Peptidase_M14 PF00246.19 EIM83831.1 - 3e-60 204.1 2.3 1.5e-57 195.3 1.6 2.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Pectinesterase PF01095.14 EIM83832.1 - 1.1e-40 139.0 1.2 1.4e-40 138.7 0.8 1.0 1 0 0 1 1 1 1 Pectinesterase Gti1_Pac2 PF09729.4 EIM83833.1 - 2.9e-36 124.8 8.5 1.2e-31 109.8 0.6 3.3 3 1 0 3 3 3 2 Gti1/Pac2 family Asp-B-Hydro_N PF05279.6 EIM83834.1 - 0.5 10.1 18.0 0.72 9.6 12.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GST_N_3 PF13417.1 EIM83835.1 - 1.2e-08 35.0 0.1 2.5e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM83835.1 - 1.5e-05 24.8 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM83835.1 - 0.045 13.6 1.1 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.1 EIM83836.1 - 2.7e-12 45.3 18.0 0.92 9.7 0.1 9.5 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.2 EIM83836.1 - 2.7e-09 36.4 16.9 0.00022 20.7 0.1 6.8 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM83836.1 - 1.8e-07 30.2 6.4 31 5.1 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.1 EIM83836.1 - 0.00015 21.4 16.7 0.0033 17.1 0.9 5.0 3 2 1 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 EIM83836.1 - 3.2 8.3 23.8 38 5.1 0.0 8.6 11 0 0 11 11 11 0 Leucine rich repeat AhpC-TSA PF00578.16 EIM83837.1 - 2.9e-20 72.2 0.0 4.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM83837.1 - 6.2e-12 45.2 0.0 9.4e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIM83838.1 - 1.2e-20 73.4 0.0 1.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM83838.1 - 3.6e-11 42.8 0.0 5.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.2 EIM83839.1 - 9e-05 22.1 3.2 0.00012 21.7 0.1 2.7 3 1 0 3 3 3 1 F-box-like Transaldolase PF00923.14 EIM83840.1 - 1.8e-93 312.8 0.1 2.1e-93 312.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase p450 PF00067.17 EIM83841.1 - 4.2e-60 203.5 0.0 1.4e-59 201.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.13 EIM83842.1 - 6.6e-33 113.7 36.6 7.6e-33 113.5 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Gram_pos_anchor PF00746.16 EIM83842.1 - 3.6 7.5 4.5 1.5 8.7 0.2 2.7 3 0 0 3 3 3 0 Gram positive anchor Bestrophin PF01062.16 EIM83843.1 - 9.7e-50 169.1 7.1 9.1e-32 110.1 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel F-box-like PF12937.2 EIM83844.1 - 1.1e-06 28.2 4.1 2.2e-06 27.2 0.8 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM83844.1 - 0.73 9.5 6.2 4.2 7.1 1.7 3.6 2 1 0 2 2 2 0 F-box domain zinc_ribbon_4 PF13717.1 EIM83845.1 - 0.2 11.3 1.0 0.36 10.5 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIM83845.1 - 0.26 10.8 1.1 0.47 10.0 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.21 EIM83845.1 - 0.45 10.9 7.0 0.13 12.7 2.5 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM83845.1 - 0.68 10.4 4.5 1.6 9.2 3.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Glyco_hydro_88 PF07470.8 EIM83846.1 - 4.2e-54 183.8 5.3 5.3e-54 183.5 3.7 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EIM83846.1 - 0.0028 16.0 0.4 0.82 7.8 0.1 2.4 1 1 0 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Resistin PF06954.6 EIM83847.1 - 2.3 8.5 6.6 0.37 11.1 2.1 1.5 2 0 0 2 2 2 0 Resistin tRNA-synt_2b PF00587.20 EIM83849.1 - 1.6e-66 223.1 0.3 3.1e-66 222.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIM83849.1 - 2.8e-20 72.0 0.1 1e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain Pheromone PF08015.6 EIM83850.1 - 0.35 11.7 4.1 0.65 10.8 2.9 1.5 1 1 0 1 1 1 0 Fungal mating-type pheromone ATG27 PF09451.5 EIM83854.1 - 1.7e-12 47.1 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EIM83854.1 - 0.00045 20.0 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat APG12 PF04110.8 EIM83856.1 - 7.9e-32 109.3 0.1 9.4e-32 109.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EIM83856.1 - 0.0078 16.1 0.0 0.009 15.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ThiF PF00899.16 EIM83859.1 - 1.5e-06 28.0 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family BTB PF00651.26 EIM83860.1 - 3.3e-06 27.0 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain zf-RanBP PF00641.13 EIM83861.1 - 0.012 14.6 0.1 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Toxin_51 PF15531.1 EIM83861.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 BTB PF00651.26 EIM83862.1 - 2e-09 37.4 0.0 1.4e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain Sld5 PF05916.6 EIM83863.1 - 0.0031 17.7 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein BTB PF00651.26 EIM83865.1 - 2.9e-09 36.9 0.2 1.9e-08 34.2 0.0 2.4 2 2 0 2 2 2 1 BTB/POZ domain DUF2673 PF10880.3 EIM83865.1 - 0.052 13.5 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) BTB PF00651.26 EIM83866.1 - 3.9e-10 39.6 0.1 5.3e-09 36.0 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain Y_phosphatase3 PF13350.1 EIM83866.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family LysM PF01476.15 EIM83867.1 - 8.1e-10 38.4 1.5 5.2e-05 23.0 0.2 2.3 2 0 0 2 2 2 2 LysM domain PepSY_2 PF13670.1 EIM83867.1 - 0.34 10.8 7.7 2.4 8.1 0.8 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 EIM83867.1 - 2.8 8.4 6.4 6.6 7.1 4.4 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein Epimerase PF01370.16 EIM83869.1 - 2.4e-17 63.1 0.0 3.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM83869.1 - 5.2e-08 31.9 0.0 1.1e-07 30.8 0.0 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM83869.1 - 8.3e-07 29.1 0.3 3.6e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM83869.1 - 1.8e-06 27.0 0.0 1.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM83869.1 - 0.00013 21.2 0.1 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM83869.1 - 0.0012 18.8 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase BTB PF00651.26 EIM83870.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2673 PF10880.3 EIM83870.1 - 0.34 10.9 1.7 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) OGFr_N PF04664.8 EIM83871.1 - 1.2e-26 93.3 0.0 7.6e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region BTB PF00651.26 EIM83872.1 - 5.4e-10 39.2 0.0 1.9e-09 37.4 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIM83873.1 - 2.7e-09 37.0 0.0 4.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain G-patch PF01585.18 EIM83874.1 - 1.2e-07 31.3 2.7 1.8e-07 30.8 0.5 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EIM83874.1 - 3.9e-05 23.4 0.3 3.9e-05 23.4 0.2 5.5 5 2 1 6 6 6 1 DExH-box splicing factor binding site SPX PF03105.14 EIM83879.1 - 7.9e-22 78.3 3.8 5.7e-10 39.4 0.3 2.6 2 1 0 2 2 2 2 SPX domain zf-C3HC4 PF00097.20 EIM83879.1 - 3.9e-07 29.6 7.2 6.5e-07 28.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM83879.1 - 8.4e-07 28.7 7.8 1.4e-06 28.0 5.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EIM83879.1 - 1.6e-06 27.7 7.6 2.9e-06 26.9 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM83879.1 - 3.5e-06 26.5 5.8 6e-06 25.8 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM83879.1 - 8.9e-06 25.6 9.6 1.5e-05 24.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIM83879.1 - 0.00054 19.5 3.1 0.0011 18.5 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EIM83879.1 - 0.00067 19.3 7.4 0.0012 18.4 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIM83879.1 - 0.0062 16.2 8.1 0.0083 15.8 4.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIM83879.1 - 0.011 15.5 3.2 0.02 14.6 2.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EIM83879.1 - 0.15 11.5 5.2 0.31 10.5 3.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EIM83879.1 - 0.31 11.1 4.6 0.84 9.7 3.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EIM83879.1 - 1.3 8.6 6.8 4.9 6.7 4.7 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Longin PF13774.1 EIM83880.1 - 2.3e-17 62.3 0.0 3.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIM83880.1 - 1.1e-14 53.7 1.1 1.9e-14 52.9 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin UPF0449 PF15136.1 EIM83880.1 - 0.087 13.0 0.2 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Tetraspannin PF00335.15 EIM83881.1 - 3e-07 29.9 1.8 3e-07 29.9 1.3 1.8 1 1 1 2 2 2 1 Tetraspanin family DUF202 PF02656.10 EIM83881.1 - 0.013 15.7 0.1 0.013 15.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ABC2_membrane_3 PF12698.2 EIM83881.1 - 0.12 11.3 6.4 0.23 10.4 4.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein IspA PF04279.10 EIM83881.1 - 0.29 11.0 5.9 2.5 8.0 3.9 2.1 1 1 0 1 1 1 0 Intracellular septation protein A DUF4131 PF13567.1 EIM83881.1 - 6.6 6.0 8.3 4.9 6.5 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ADH_N PF08240.7 EIM83882.1 - 0.00042 20.0 0.4 0.0065 16.2 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM83882.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MAP65_ASE1 PF03999.7 EIM83882.1 - 0.58 8.6 1.8 0.74 8.3 1.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_L38e PF01781.13 EIM83883.1 - 1.9e-31 107.5 1.6 2.3e-31 107.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.4 EIM83883.1 - 0.025 14.0 0.1 0.1 12.0 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) ADH_zinc_N PF00107.21 EIM83884.1 - 5.1e-14 51.9 0.0 8.8e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM83884.1 - 1.3e-07 31.3 0.2 7.1e-06 25.7 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM83884.1 - 0.00024 21.9 0.0 0.00079 20.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase WD40 PF00400.27 EIM83885.1 - 7e-27 92.3 1.0 1.1e-10 40.9 0.1 5.3 4 1 0 4 4 4 4 WD domain, G-beta repeat Peptidase_M50 PF02163.17 EIM83886.1 - 4.1e-13 48.7 0.0 9.6e-12 44.2 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M50 Nrap PF03813.9 EIM83887.1 - 2.6e-200 667.4 0.0 2.2e-199 664.3 0.0 2.0 1 1 0 1 1 1 1 Nrap protein ADH_zinc_N PF00107.21 EIM83888.1 - 5.3e-21 74.5 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM83888.1 - 3.5e-10 39.6 0.0 6.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM83888.1 - 3.7e-06 27.8 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiG_N PF11760.3 EIM83888.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal BTB PF00651.26 EIM83889.1 - 3.7e-07 30.1 0.0 8.6e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM83890.1 - 1.3e-09 37.9 0.0 2.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CMAS PF02353.15 EIM83891.1 - 1.6e-63 214.3 0.2 1.9e-63 214.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIM83891.1 - 3.2e-11 43.2 0.0 9.5e-11 41.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM83891.1 - 2.4e-09 37.5 0.0 1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM83891.1 - 4.6e-07 30.4 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM83891.1 - 8.1e-06 26.2 0.0 1.5e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM83891.1 - 3.4e-05 23.8 0.0 0.00016 21.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EIM83891.1 - 0.00058 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 EIM83891.1 - 0.00068 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM83891.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIM83891.1 - 0.002 17.7 0.0 0.0061 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EIM83891.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EIM83891.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CAP59_mtransfer PF11735.3 EIM83892.1 - 2.7e-54 183.9 0.0 3.5e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 YIF1 PF03878.10 EIM83893.1 - 3.8e-76 255.3 0.2 4.9e-76 255.0 0.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EIM83893.1 - 2.8e-06 26.9 1.8 6.1e-06 25.8 1.2 1.5 1 0 0 1 1 1 1 Yip1 domain DUF4131 PF13567.1 EIM83893.1 - 0.77 9.1 5.4 1.1 8.6 3.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 EIM83894.1 - 0.00022 20.8 0.5 0.00078 19.1 0.3 2.0 1 0 0 1 1 1 1 F-box-like CPL PF08144.6 EIM83895.1 - 1.3e-17 64.0 4.2 1.3e-16 60.7 0.0 3.9 4 1 0 4 4 4 1 CPL (NUC119) domain Peptidase_S10 PF00450.17 EIM83897.1 - 6e-102 341.9 0.1 7.3e-102 341.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIM83897.1 - 4.4e-06 26.7 0.0 3.9e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EIM83898.1 - 2.1e-12 46.4 17.0 7.2e-08 32.0 0.2 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat C1_3 PF07649.7 EIM83898.1 - 0.06 13.3 7.5 0.024 14.6 2.0 2.4 2 0 0 2 2 2 0 C1-like domain Herpes_ORF11 PF04797.8 EIM83898.1 - 0.092 11.1 0.1 0.17 10.3 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DUF1427 PF07235.6 EIM83898.1 - 0.2 11.7 0.5 0.45 10.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) C1_2 PF03107.11 EIM83898.1 - 6 7.0 7.3 2.8 8.1 1.9 2.3 2 0 0 2 2 2 0 C1 domain Glyco_hydro_cc PF11790.3 EIM83899.1 - 4.9e-35 121.0 0.0 6.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 EIM83901.1 - 5.7e-36 124.1 0.1 6.5e-36 123.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Abhydrolase_6 PF12697.2 EIM83902.1 - 6.6e-16 58.8 0.1 8.3e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM83902.1 - 3e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Catalase PF00199.14 EIM83913.1 - 3.9e-179 595.2 0.7 5e-179 594.9 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIM83913.1 - 2.8e-16 59.1 0.1 2.8e-16 59.1 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive vATP-synt_E PF01991.13 EIM83915.1 - 4e-52 176.3 8.9 4.7e-52 176.1 6.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF45 PF01863.12 EIM83915.1 - 0.029 14.1 2.5 0.041 13.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Vfa1 PF08432.5 EIM83915.1 - 0.31 11.0 7.2 0.49 10.3 5.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF883 PF05957.8 EIM83915.1 - 4.1 7.8 8.7 1.2 9.5 2.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TFIIB PF00382.14 EIM83916.1 - 3.3e-37 126.1 0.4 9.3e-19 67.0 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EIM83916.1 - 1.8e-23 82.5 3.5 1.8e-23 82.5 2.4 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EIM83916.1 - 2.4e-07 30.3 0.2 0.013 15.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 EIM83916.1 - 2.9e-07 29.7 3.2 7.3e-07 28.3 2.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EIM83916.1 - 0.0089 15.5 1.8 0.0089 15.5 1.2 1.9 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 EIM83916.1 - 0.041 13.3 1.3 0.077 12.4 0.9 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Asp PF00026.18 EIM83917.1 - 1.9e-35 122.6 9.6 5.1e-35 121.2 6.7 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM83917.1 - 1.3e-05 25.1 1.7 0.00039 20.3 1.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM83917.1 - 0.047 13.2 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal HDPD PF02924.9 EIM83917.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Hydantoinase_A PF01968.13 EIM83918.1 - 2e-91 306.1 0.1 3.7e-91 305.2 0.0 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM83918.1 - 7.9e-55 185.0 0.3 1.1e-51 174.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EIM83918.1 - 0.00033 20.0 0.0 0.017 14.4 0.0 2.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.2 EIM83919.1 - 8.1e-10 38.2 0.2 4.2e-09 35.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM83919.1 - 1.7e-07 30.7 0.0 1.7e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 F-box domain rRNA_proc-arch PF13234.1 EIM83920.1 - 3.6e-93 311.5 0.0 5.2e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EIM83920.1 - 3.7e-60 202.2 0.3 7.1e-60 201.3 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIM83920.1 - 1.8e-21 76.3 1.4 3e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM83920.1 - 1.7e-06 27.8 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EIM83920.1 - 0.0077 15.1 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein CENP-F_leu_zip PF10473.4 EIM83920.1 - 0.29 10.9 7.8 0.05 13.4 0.5 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L14 PF00238.14 EIM83921.1 - 1.2e-32 112.2 0.0 1.3e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ADH_zinc_N PF00107.21 EIM83922.1 - 2e-20 72.6 0.0 3.9e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM83922.1 - 6.3e-07 30.3 0.0 1.1e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transformer PF06495.6 EIM83923.1 - 0.24 11.2 3.4 0.3 10.9 2.4 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Period_C PF12114.3 EIM83923.1 - 0.46 10.0 10.4 0.62 9.6 7.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 EIM83923.1 - 1 7.5 7.3 1.1 7.5 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein FRQ PF09421.5 EIM83923.1 - 2.3 5.8 10.7 2.9 5.5 7.4 1.0 1 0 0 1 1 1 0 Frequency clock protein Myosin_N PF02736.14 EIM83924.1 - 2.1e-09 36.9 0.5 2.6e-09 36.5 0.3 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.16 EIM83925.1 - 1.6e-48 165.3 0.0 1.7e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 EIM83925.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM83925.1 - 0.0058 16.6 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIM83925.1 - 0.0075 14.9 0.0 0.0091 14.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EIM83925.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIM83925.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EIM83925.1 - 0.022 14.4 0.2 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.13 EIM83925.1 - 0.026 14.0 0.1 0.076 12.4 0.1 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family Hpr_kinase_C PF07475.7 EIM83925.1 - 0.058 12.6 0.1 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.1 EIM83925.1 - 0.059 12.8 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EIM83925.1 - 0.082 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EIM83925.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Myosin_head PF00063.16 EIM83926.1 - 4.9e-72 243.0 0.0 5.6e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.16 EIM83927.1 - 3.6e-52 177.3 0.0 4.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EIM83928.1 - 0.004 14.9 42.3 0.0068 14.1 19.2 2.5 1 1 1 2 2 2 2 Myosin tail ADIP PF11559.3 EIM83928.1 - 0.0041 17.0 1.7 0.0041 17.0 1.2 3.2 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EIM83928.1 - 0.24 10.5 10.6 0.12 11.5 3.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EIM83928.1 - 0.26 11.0 26.8 0.049 13.3 8.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Img2 PF05046.9 EIM83928.1 - 0.34 11.1 2.7 0.52 10.5 0.1 2.3 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Atg14 PF10186.4 EIM83928.1 - 0.72 8.7 27.7 3.3e+02 -0.0 19.2 2.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EIM83928.1 - 1.6 8.8 16.8 0.11 12.6 3.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.4 EIM83928.1 - 2.1 8.2 18.8 0.6 10.0 10.9 1.7 2 1 0 2 2 2 0 Zinc finger-containing protein FlxA PF14282.1 EIM83928.1 - 3.2 7.7 21.6 0.36 10.8 2.7 3.1 1 1 1 3 3 3 0 FlxA-like protein DUF4200 PF13863.1 EIM83928.1 - 5.8 6.8 32.1 4.3 7.3 7.8 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) IncA PF04156.9 EIM83928.1 - 7.1 6.1 33.2 56 3.2 21.1 2.3 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EIM83928.1 - 8.3 5.5 25.9 1.7 7.8 12.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIM83928.1 - 9.3 5.1 25.7 6.4 5.7 15.5 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EIM83928.1 - 9.4 5.9 30.2 3.9 7.2 9.9 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EIM83929.1 - 1.9e-08 32.5 32.9 1.1e-07 29.9 22.8 1.8 1 1 0 1 1 1 1 Myosin tail Tropomyosin_1 PF12718.2 EIM83929.1 - 1.1e-05 25.3 31.7 0.0026 17.5 11.9 3.1 1 1 2 3 3 3 2 Tropomyosin like AAA_13 PF13166.1 EIM83929.1 - 0.0039 15.7 16.7 0.0051 15.3 11.6 1.1 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EIM83929.1 - 0.0053 16.2 29.4 0.11 11.9 5.3 3.1 1 1 2 3 3 3 2 Intermediate filament protein DUF4200 PF13863.1 EIM83929.1 - 0.012 15.5 9.1 0.012 15.5 6.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Zw10 PF06248.8 EIM83929.1 - 0.019 13.1 7.7 0.029 12.5 5.4 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Vac_Fusion PF02346.11 EIM83929.1 - 0.071 12.5 11.2 0.1 12.0 0.1 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein CENP-F_leu_zip PF10473.4 EIM83929.1 - 0.16 11.8 36.3 0.42 10.4 11.7 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4497 PF14924.1 EIM83929.1 - 0.17 12.2 1.2 0.54 10.5 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) AKNA PF12443.3 EIM83929.1 - 0.31 11.0 9.8 0.029 14.3 1.5 2.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor Reo_sigmaC PF04582.7 EIM83929.1 - 0.52 9.4 6.7 0.88 8.6 1.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliD_C PF07195.7 EIM83929.1 - 0.95 8.7 16.2 32 3.7 1.0 3.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 EIM83929.1 - 1.3 8.5 33.3 8.2 5.9 10.9 2.3 1 1 1 2 2 2 0 IncA protein Cast PF10174.4 EIM83929.1 - 1.4 6.9 34.6 23 2.8 24.4 2.0 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 EIM83929.1 - 1.6 8.2 37.9 5.7 6.3 13.2 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc24 PF08286.6 EIM83929.1 - 2.2 7.9 28.3 0.12 12.1 5.1 4.4 2 2 1 3 3 3 0 Spc24 subunit of Ndc80 Nsp1_C PF05064.8 EIM83929.1 - 2.5 7.7 19.1 6.1 6.5 3.6 4.1 1 1 2 4 4 4 0 Nsp1-like C-terminal region ATG16 PF08614.6 EIM83929.1 - 4.3 7.1 28.7 8.7 6.1 7.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 EIM83929.1 - 5.7 6.7 20.0 1.8 8.3 3.0 3.0 1 1 1 2 2 2 0 Laminin Domain II MbeD_MobD PF04899.7 EIM83929.1 - 5.9 6.8 19.2 0.38 10.6 1.9 4.1 2 2 2 4 4 4 0 MbeD/MobD like SseC PF04888.7 EIM83929.1 - 7.2 5.8 16.3 1.3 8.2 3.0 2.9 1 1 2 3 3 3 0 Secretion system effector C (SseC) like family OPT PF03169.10 EIM83930.1 - 6.7e-140 467.4 47.2 2.7e-81 273.8 17.3 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Ras PF00071.17 EIM83932.1 - 2e-34 118.3 0.4 2.4e-34 118.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM83932.1 - 1.4e-23 83.6 0.1 9e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM83932.1 - 6e-08 32.1 0.1 7.7e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM83932.1 - 7.3e-08 31.8 0.3 9.2e-08 31.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM83932.1 - 0.0094 15.8 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIM83932.1 - 0.014 14.1 0.3 0.031 12.9 0.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit DLIC PF05783.6 EIM83932.1 - 0.069 11.8 0.0 7 5.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.4 EIM83932.1 - 0.12 11.9 0.4 0.54 9.7 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mid2 PF04478.7 EIM83933.1 - 0.0062 15.9 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.2 EIM83933.1 - 0.0085 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Glyco_hydro_7 PF00840.15 EIM83934.1 - 1.5e-198 659.5 11.6 1.7e-198 659.3 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ADH_zinc_N PF00107.21 EIM83937.1 - 2.9e-20 72.1 0.0 5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM83937.1 - 2.2e-08 35.0 0.0 3.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIM83937.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Ribosomal_L6 PF00347.18 EIM83938.1 - 0.11 13.0 1.0 0.15 12.5 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein L6 RRM_1 PF00076.17 EIM83939.1 - 1e-16 60.2 0.0 1.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM83939.1 - 1e-15 57.4 0.0 2.6e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM83939.1 - 3.2e-11 42.9 0.0 4.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.21 EIM83940.1 - 3.3e-21 75.1 0.0 6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM83940.1 - 7.4e-06 26.8 0.0 1.5e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M50 PF02163.17 EIM83940.1 - 0.064 12.2 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 NAD_binding_10 PF13460.1 EIM83940.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Peptidase_C14 PF00656.17 EIM83942.1 - 4.9e-23 82.0 0.0 9.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HAD_2 PF13419.1 EIM83943.1 - 1.1e-28 100.5 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM83943.1 - 5.1e-05 22.9 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM83943.1 - 0.00013 22.4 0.0 0.00051 20.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIM83943.1 - 0.057 13.3 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FAD-oxidase_C PF02913.14 EIM83944.1 - 1.5e-56 191.5 0.0 3.7e-56 190.2 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIM83944.1 - 2.2e-30 104.9 0.0 4e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain E1-E2_ATPase PF00122.15 EIM83945.1 - 1.5e-20 73.2 0.1 1.2e-19 70.2 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIM83945.1 - 9.2e-20 71.9 0.0 6.8e-19 69.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM83945.1 - 1.8e-19 70.6 0.0 4.4e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIM83945.1 - 0.00067 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM83945.1 - 0.048 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM83945.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pox_P21 PF05313.7 EIM83945.1 - 0.18 11.0 2.8 0.37 10.0 1.9 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein UQ_con PF00179.21 EIM83946.1 - 4.6e-33 113.6 0.0 1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADH_zinc_N PF00107.21 EIM83947.1 - 1.9e-21 75.9 0.0 3.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM83947.1 - 6.9e-09 36.6 0.0 1.2e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2236 PF09995.4 EIM83948.1 - 3e-16 59.4 0.1 4.8e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF4393 PF14337.1 EIM83948.1 - 0.047 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Pyr_redox_2 PF07992.9 EIM83952.1 - 1.9e-21 76.8 0.0 3.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM83952.1 - 1.3e-10 41.5 0.1 1.6e-09 38.0 0.0 2.8 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM83952.1 - 0.035 14.1 0.7 4.4 7.3 0.0 3.1 3 2 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4342 PF14242.1 EIM83952.1 - 0.31 10.8 1.9 0.62 9.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) Glyco_hyd_65N_2 PF14498.1 EIM83954.1 - 5.6e-42 144.0 0.2 1e-41 143.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain FMO-like PF00743.14 EIM83955.1 - 1.6e-29 102.5 0.0 4.3e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM83955.1 - 4.2e-13 49.8 0.0 1e-12 48.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM83955.1 - 5.4e-10 38.7 0.1 5.9e-06 25.4 0.0 3.3 2 1 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIM83955.1 - 3.6e-07 30.1 0.3 0.00015 21.6 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM83955.1 - 3.8e-05 23.6 0.0 0.01 15.7 0.0 3.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM83955.1 - 0.0012 18.8 2.0 0.0053 16.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM83955.1 - 0.086 11.9 0.2 4.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 EIM83955.1 - 0.15 12.3 0.4 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIM83955.1 - 0.18 11.9 0.4 11 6.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EIM83956.1 - 0.12 13.2 0.0 0.31 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain F-box PF00646.28 EIM83958.1 - 0.0017 17.9 0.2 0.0098 15.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM83958.1 - 0.024 14.3 1.3 0.073 12.7 0.1 2.5 3 0 0 3 3 3 0 F-box-like EPSP_synthase PF00275.15 EIM83959.1 - 6.6e-120 400.3 0.0 1e-119 399.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EIM83959.1 - 6.1e-98 326.8 0.0 2e-97 325.2 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EIM83959.1 - 5.5e-62 209.3 0.0 8.3e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EIM83959.1 - 1e-32 113.1 0.0 2.3e-31 108.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EIM83959.1 - 2.3e-24 85.2 0.0 5.8e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EIM83959.1 - 2e-13 50.6 0.0 8.6e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EIM83959.1 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EIM83959.1 - 4.9e-05 24.1 0.0 0.00014 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM83959.1 - 0.095 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EIM83959.1 - 0.22 11.3 0.0 0.83 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltransf_2 PF00891.13 EIM83960.1 - 2.8e-31 108.5 0.0 4.7e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EIM83960.1 - 0.0073 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RCC1 PF00415.13 EIM83961.1 - 9e-48 160.2 5.1 7.5e-09 35.6 0.2 8.4 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM83961.1 - 4.1e-26 89.9 29.0 2.8e-05 23.5 0.5 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat S4 PF01479.20 EIM83962.1 - 2.1e-12 46.2 0.1 3.8e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EIM83962.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ferric_reduct PF01794.14 EIM83963.1 - 3.4e-14 53.0 3.7 7.3e-14 51.9 2.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIM83963.1 - 5e-08 32.7 0.0 9.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIM83963.1 - 3.5e-07 30.2 0.0 1.3e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain GWT1 PF06423.7 EIM83964.1 - 5.1 7.1 12.0 0.57 10.2 2.7 2.4 1 1 0 2 2 2 0 GWT1 ADH_zinc_N_2 PF13602.1 EIM83965.1 - 2e-19 70.7 0.0 7.8e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM83965.1 - 3.6e-17 62.1 0.0 6.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3317 PF11779.3 EIM83966.1 - 1.6e-09 37.0 6.9 2.3e-09 36.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Spc97_Spc98 PF04130.8 EIM83967.1 - 2.9e-118 395.5 0.0 3.5e-118 395.2 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family ADH_zinc_N_2 PF13602.1 EIM83968.1 - 4.2e-20 72.9 0.0 9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG_box PF00505.14 EIM83968.1 - 6.2e-16 58.4 5.3 1.9e-10 40.8 0.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box ADH_zinc_N PF00107.21 EIM83968.1 - 4.1e-15 55.4 0.0 8.1e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG_box_2 PF09011.5 EIM83968.1 - 8.4e-15 54.8 3.1 1.2e-06 28.7 0.1 2.7 2 0 0 2 2 2 2 HMG-box domain DUF3460 PF11943.3 EIM83968.1 - 0.032 14.2 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) HNOB PF07700.10 EIM83968.1 - 0.21 11.0 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding DUF1104 PF06518.6 EIM83968.1 - 0.63 10.1 3.0 0.47 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) FAD_binding_3 PF01494.14 EIM83969.1 - 2.3e-15 56.5 0.0 4.5e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM83969.1 - 1.4e-06 27.5 4.1 0.0025 16.7 0.2 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM83969.1 - 4.4e-06 26.5 1.0 1.8e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIM83969.1 - 5.2e-05 23.1 0.2 0.00014 21.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIM83969.1 - 0.00069 18.8 0.1 0.017 14.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EIM83969.1 - 0.0008 18.1 0.3 0.33 9.5 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EIM83969.1 - 0.0014 17.5 1.4 0.003 16.4 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM83969.1 - 0.0055 15.2 0.1 2.1 6.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EIM83969.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EIM83969.1 - 0.022 14.3 0.2 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EIM83969.1 - 0.08 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EIM83969.1 - 0.16 12.4 0.2 3.2 8.2 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nuclease_act PF08133.6 EIM83969.1 - 1.4 8.4 3.7 0.48 9.9 0.3 1.8 2 0 0 2 2 2 0 Anticodon nuclease activator family Acetyltransf_1 PF00583.19 EIM83970.1 - 7.7e-08 32.2 0.0 2.1e-07 30.8 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM83970.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM83970.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM83970.1 - 0.0047 17.0 0.0 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NMT PF01233.14 EIM83970.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_CG PF14542.1 EIM83970.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.9 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIM83970.1 - 0.076 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.1 EIM83970.1 - 0.11 12.1 0.3 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.1 EIM83970.1 - 0.16 11.8 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TP2 PF01254.13 EIM83970.1 - 0.51 10.6 4.4 0.46 10.8 0.1 2.2 2 0 0 2 2 2 0 Nuclear transition protein 2 AP_endonuc_2 PF01261.19 EIM83971.1 - 2.2e-25 89.2 0.0 3.3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_16 PF00722.16 EIM83972.1 - 1.2e-13 50.7 0.8 1.2e-13 50.7 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EIM83973.1 - 9e-54 182.1 0.7 2.7e-53 180.5 0.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM83973.1 - 3.2e-08 33.6 0.0 1.9e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIM83973.1 - 0.00026 20.7 0.1 0.029 14.0 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM83973.1 - 0.061 12.6 0.0 0.19 10.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 CUE PF02845.11 EIM83974.1 - 1.5e-07 30.7 0.0 2.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain Pkinase PF00069.20 EIM83975.1 - 1.3e-70 237.5 0.0 1.6e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM83975.1 - 8.3e-33 113.5 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIM83975.1 - 9e-10 38.9 2.2 3.3e-09 37.1 1.5 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIM83975.1 - 0.00089 18.3 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM83975.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM83975.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNARE PF05739.14 EIM83978.1 - 9.9e-13 47.5 1.0 9.9e-13 47.5 0.7 2.3 1 1 1 2 2 2 1 SNARE domain Sec20 PF03908.8 EIM83978.1 - 0.015 14.9 0.3 0.015 14.9 0.2 2.3 2 1 1 3 3 3 0 Sec20 Fusion_gly PF00523.13 EIM83978.1 - 0.018 13.0 0.2 0.028 12.5 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 YjcZ PF13990.1 EIM83978.1 - 0.046 12.8 0.4 0.046 12.8 0.3 1.5 2 0 0 2 2 2 0 YjcZ-like protein Tropomyosin PF00261.15 EIM83978.1 - 0.093 11.8 2.5 0.091 11.8 0.5 1.7 2 0 0 2 2 2 0 Tropomyosin GATase PF00117.23 EIM83979.1 - 3.4e-06 26.6 0.0 1.6e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIM83979.1 - 0.085 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 DIOX_N PF14226.1 EIM83980.1 - 1.5e-15 57.7 0.0 3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM83980.1 - 5.1e-09 36.3 0.0 1.7e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CLAMP PF14769.1 EIM83980.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Mito_carr PF00153.22 EIM83981.1 - 1e-56 188.5 0.3 1.6e-18 66.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.8 EIM83982.1 - 3.4e-49 167.1 0.0 3.9e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM83982.1 - 8.5e-17 61.7 0.0 1.5e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM83982.1 - 9.7e-06 24.4 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM83982.1 - 7.1e-05 22.3 0.0 0.00024 20.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM83982.1 - 0.0046 16.6 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM83982.1 - 0.0065 16.3 0.1 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 EIM83984.1 - 1.2e-39 136.0 29.0 1.2e-39 136.0 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM83984.1 - 1.1e-15 57.1 9.1 1.1e-15 57.1 6.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIM83984.1 - 0.00011 20.5 1.5 0.00011 20.5 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 EIM83985.1 - 3.4e-50 170.4 0.0 3.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ish1 PF10281.4 EIM83985.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Aldo_ket_red PF00248.16 EIM83986.1 - 4.5e-50 170.0 0.0 5.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 EIM83988.1 - 1.9e-16 60.0 0.0 3.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM83988.1 - 4.1e-08 33.1 0.5 8.6e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM83988.1 - 4.7e-08 32.3 0.1 3.4e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM83988.1 - 8.1e-07 28.2 0.1 1.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM83988.1 - 0.00046 20.1 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM83988.1 - 0.0022 16.9 0.1 0.0098 14.8 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM83988.1 - 0.0029 16.1 0.0 0.0043 15.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EIM83988.1 - 0.0042 17.4 0.3 0.0095 16.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM83988.1 - 0.0068 15.5 0.9 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EIM83988.1 - 0.0082 15.2 0.1 0.19 10.7 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIM83988.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM83988.1 - 0.027 14.2 0.1 0.076 12.7 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EIM83988.1 - 0.056 12.2 0.6 0.086 11.6 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Abhydrolase_1 PF00561.15 EIM83989.1 - 3.3e-08 33.3 0.0 8e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM83989.1 - 1.8e-07 30.9 0.0 1.2e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM83989.1 - 1.2e-06 28.6 0.0 2.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM83989.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Aldo_ket_red PF00248.16 EIM83990.1 - 1.2e-45 155.5 0.0 1.5e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_P_p30 PF01876.11 EIM83991.1 - 3.8e-28 97.6 0.0 6.4e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Ndc1_Nup PF09531.5 EIM83992.1 - 1.6e-31 109.4 2.6 3e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Paf67 PF10255.4 EIM83993.1 - 2.4e-148 494.3 0.0 3.1e-148 493.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EIM83993.1 - 0.023 14.6 0.0 0.29 11.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM83993.1 - 0.031 14.2 0.0 3.3 7.7 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat PAP_assoc PF03828.14 EIM83995.1 - 7.2e-06 25.8 0.0 0.0018 18.2 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIM83995.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 EIM83995.1 - 0.0022 17.8 0.1 0.54 10.1 0.0 2.8 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain F-box-like PF12937.2 EIM83996.1 - 1.3e-08 34.3 0.7 3.9e-08 32.8 0.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM83996.1 - 0.0066 16.1 0.3 0.18 11.5 0.0 3.2 3 0 0 3 3 3 1 Leucine rich repeat F-box PF00646.28 EIM83996.1 - 0.0071 15.9 5.5 0.014 15.0 1.4 3.1 2 1 0 2 2 2 1 F-box domain Solute_trans_a PF03619.11 EIM83997.1 - 3.1e-99 331.7 7.4 4e-99 331.3 5.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-MYND PF01753.13 EIM84000.1 - 1.8e-08 34.0 11.6 1.8e-08 34.0 8.0 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EIM84000.1 - 0.15 11.9 2.2 0.38 10.6 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 C2 PF00168.25 EIM84001.1 - 1.3e-21 76.2 0.0 6.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain Inhibitor_I78 PF11720.3 EIM84003.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I78 family Med8 PF10232.4 EIM84004.1 - 8.1e-09 35.3 5.7 1.5e-08 34.4 4.0 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 QRPTase_C PF01729.14 EIM84004.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain F-box-like PF12937.2 EIM84005.1 - 7.9e-06 25.5 1.5 7.4e-05 22.4 0.1 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIM84005.1 - 0.22 11.2 3.9 11 5.7 0.0 4.0 4 0 0 4 4 4 0 F-box domain NmrA PF05368.8 EIM84006.1 - 8.9e-39 133.1 0.0 2.1e-38 131.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EIM84006.1 - 5.3e-10 39.6 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF927 PF06048.6 EIM84006.1 - 0.04 13.1 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Rib_5-P_isom_A PF06026.9 EIM84007.1 - 8.1e-54 181.5 0.0 1.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Tbf5 PF06331.7 EIM84008.1 - 1e-12 47.5 0.6 1.1e-12 47.5 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF3906 PF13046.1 EIM84008.1 - 0.12 12.0 0.5 0.35 10.5 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3906) dsrm PF00035.20 EIM84010.1 - 3e-05 24.5 0.1 9.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Pex19 PF04614.7 EIM84011.1 - 2e-50 171.7 16.0 8.6e-50 169.6 11.1 1.9 1 1 0 1 1 1 1 Pex19 protein family RGS PF00615.14 EIM84012.1 - 2.5e-09 37.2 0.3 0.00031 20.8 0.0 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF2516 PF10724.4 EIM84012.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) O-antigen_lig PF13425.1 EIM84012.1 - 2.4 8.1 7.2 2.3 8.1 2.5 2.6 2 1 1 3 3 3 0 O-antigen ligase like membrane protein L51_S25_CI-B8 PF05047.11 EIM84013.1 - 7.5e-13 48.0 0.0 1.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NmrA PF05368.8 EIM84014.1 - 4.3e-38 130.8 0.0 6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM84014.1 - 8.4e-10 38.9 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIM84014.1 - 0.031 14.1 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EIM84014.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain F-box-like PF12937.2 EIM84015.1 - 5.5e-06 26.0 0.4 1.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM84015.1 - 0.094 12.4 0.0 1.1e+02 2.5 0.0 4.3 4 0 0 4 4 4 0 Leucine rich repeat CHAT PF12770.2 EIM84016.1 - 1.2e-27 96.8 0.1 2.9e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM84016.1 - 0.026 14.4 14.3 7.9 6.4 0.0 6.6 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM84016.1 - 0.029 14.0 11.7 0.057 13.0 0.0 5.7 5 3 3 8 8 8 0 TPR repeat TPR_14 PF13428.1 EIM84016.1 - 0.44 11.3 9.0 7.1 7.5 0.0 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84016.1 - 3.4 8.4 0.0 3.4 8.4 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 EIM84017.1 - 2.8e-63 213.9 0.0 4.7e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.20 EIM84018.1 - 5.7e-61 205.9 0.0 7.2e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84018.1 - 1.1e-28 100.0 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM84018.1 - 8.8e-08 31.4 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM84018.1 - 0.0062 16.2 0.3 0.023 14.4 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM84018.1 - 0.085 11.9 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 EIM84019.1 - 1.6e-46 158.3 0.0 1.8e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.14 EIM84020.1 - 2e-52 178.2 0.0 5.1e-52 176.8 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 EIM84020.1 - 1.1e-12 47.8 0.2 2.4e-12 46.7 0.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain MFS_1 PF07690.11 EIM84021.1 - 4.2e-43 147.4 25.2 4.2e-43 147.4 17.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM84021.1 - 5.4e-14 51.6 0.3 5.4e-14 51.6 0.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIM84021.1 - 2.7e-05 22.5 0.7 4.3e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIM84021.1 - 0.0008 17.6 8.1 0.0015 16.7 5.4 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector LysM PF01476.15 EIM84022.1 - 3e-07 30.2 1.1 6.1e-05 22.8 0.0 2.9 2 1 0 2 2 2 2 LysM domain Paramecium_SA PF01508.11 EIM84022.1 - 4.5 7.5 7.6 11 6.2 0.1 3.1 3 0 0 3 3 3 0 Paramecium surface antigen domain APH PF01636.18 EIM84023.1 - 0.00013 21.7 1.1 0.00025 20.8 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RsbRD_N PF14361.1 EIM84024.1 - 0.13 12.7 0.4 0.39 11.1 0.0 1.9 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Acetyltransf_10 PF13673.1 EIM84025.1 - 0.15 12.1 0.0 0.59 10.2 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EIM84026.1 - 8.3e-16 57.6 30.5 1.2e-15 57.1 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.15 EIM84028.1 - 1.6e-35 121.9 0.0 2.7e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM84028.1 - 1.9e-12 47.1 1.5 1.9e-12 47.1 1.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1049 PF06305.6 EIM84029.1 - 0.12 11.9 0.5 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Alpha-amylase PF00128.19 EIM84030.1 - 2.4e-99 332.6 0.7 7.3e-99 331.1 0.2 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_42C PF08533.5 EIM84030.1 - 0.003 17.0 0.3 0.0088 15.5 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.1 EIM84030.1 - 0.0034 16.3 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Cyc-maltodext_C PF10438.4 EIM84030.1 - 0.0054 16.7 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain AA_permease PF00324.16 EIM84031.1 - 2.3e-113 379.1 35.3 2.7e-113 378.8 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM84031.1 - 3e-37 128.1 36.1 3.6e-37 127.9 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.7 EIM84031.1 - 0.19 11.7 0.1 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) PBP PF01161.15 EIM84033.1 - 3.6e-24 85.2 0.1 4.5e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GlyL_C PF12524.3 EIM84033.1 - 5.7 6.9 6.7 6 6.8 0.3 2.9 2 1 1 3 3 3 0 dsDNA virus glycoprotein L C terminal DUF4224 PF13986.1 EIM84034.1 - 0.051 13.1 0.1 0.099 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF896 PF05979.7 EIM84034.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Zn_clus PF00172.13 EIM84035.1 - 0.014 15.2 0.5 0.014 15.2 0.3 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.21 EIM84037.1 - 0.001 19.1 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Rubella_E1 PF05748.6 EIM84037.1 - 0.037 12.6 0.1 0.05 12.2 0.1 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 ArfGap PF01412.13 EIM84038.1 - 1.1 9.0 10.7 2.1 8.1 7.4 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Zn_Tnp_IS91 PF14319.1 EIM84038.1 - 4.3 6.8 18.3 0.053 13.0 5.4 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain DZR PF12773.2 EIM84038.1 - 5.2 6.9 13.1 12 5.8 2.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.1 EIM84038.1 - 10 5.4 11.2 1.1 8.4 4.2 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger RVT_1 PF00078.22 EIM84039.1 - 2.3e-07 30.3 0.0 2.5e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIM84040.1 - 1.4e-14 53.9 0.1 6.5e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM84040.1 - 2.2e-05 24.1 9.9 0.0083 16.0 1.6 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.1 EIM84040.1 - 0.076 12.7 2.6 0.21 11.2 1.8 1.7 1 0 0 1 1 1 0 Nudix N-terminal zf-CCHC_4 PF14392.1 EIM84040.1 - 0.18 11.4 4.6 3.5 7.3 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle NPV_P10 PF05531.7 EIM84040.1 - 0.67 10.2 4.6 3.9 7.7 0.6 3.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RNase_H PF00075.19 EIM84041.1 - 0.00024 21.4 0.0 0.00048 20.4 0.0 1.5 2 0 0 2 2 2 1 RNase H DUF3756 PF12581.3 EIM84041.1 - 0.063 12.9 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) Asp_protease_2 PF13650.1 EIM84042.1 - 0.00019 21.8 0.0 0.00054 20.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.1 EIM84043.1 - 3.6e-05 23.5 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.27 EIM84044.1 - 8.7e-146 469.2 44.9 9.9e-13 47.4 0.0 12.9 13 0 0 13 13 13 12 WD domain, G-beta repeat Nup160 PF11715.3 EIM84044.1 - 3.3e-17 61.8 23.5 0.15 10.1 0.5 10.6 1 1 9 10 10 10 8 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EIM84044.1 - 4.9e-10 38.5 3.0 0.3 9.6 0.0 5.6 3 1 2 5 5 5 4 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 EIM84044.1 - 3.1e-09 35.6 20.7 0.0016 16.7 0.5 6.4 1 1 6 8 8 8 4 Cytochrome D1 heme domain DUF1258 PF06869.7 EIM84044.1 - 1.4e-08 34.1 1.3 1.3 8.0 0.0 6.5 3 1 3 6 6 6 2 Protein of unknown function (DUF1258) NACHT PF05729.7 EIM84044.1 - 1.3e-06 28.1 0.0 3.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM84044.1 - 3.5e-05 23.8 0.0 9.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.1 EIM84044.1 - 0.0002 21.5 14.1 5.1 7.5 0.0 8.8 9 2 1 10 10 10 1 PQQ-like domain NB-ARC PF00931.17 EIM84044.1 - 0.00037 19.4 0.0 0.00078 18.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EIM84044.1 - 0.0076 16.4 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM84044.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PQQ PF01011.16 EIM84044.1 - 0.032 13.7 0.7 82 3.0 0.0 5.1 6 0 0 6 6 6 0 PQQ enzyme repeat PLD_C PF12357.3 EIM84044.1 - 0.055 13.0 5.8 40 3.8 0.0 6.4 9 1 0 9 9 8 0 Phospholipase D C terminal APS_kinase PF01583.15 EIM84044.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EIM84044.1 - 0.12 12.5 0.3 1.1 9.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase MIP-T3 PF10243.4 EIM84045.1 - 0.0013 17.2 30.2 0.0015 17.0 20.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1154 PF06631.6 EIM84045.1 - 0.016 14.8 3.7 0.016 14.8 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Med21 PF11221.3 EIM84045.1 - 0.11 12.4 0.2 0.11 12.4 0.1 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex CENP-T PF15511.1 EIM84045.1 - 0.51 9.5 34.9 0.85 8.8 24.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T LysM PF01476.15 EIM84046.1 - 7.4e-14 51.3 0.0 4.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 LysM domain PfkB PF00294.19 EIM84047.1 - 5.2e-30 104.5 0.0 1.8e-29 102.8 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HpcH_HpaI PF03328.9 EIM84048.1 - 2.8e-30 104.8 0.2 3.4e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GARS_N PF02844.10 EIM84048.1 - 0.037 14.4 0.9 2.9 8.4 0.1 3.0 2 1 1 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain Sugar_tr PF00083.19 EIM84049.1 - 3.3e-99 332.5 20.1 3.7e-99 332.3 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84049.1 - 6.6e-30 104.0 24.8 3.2e-29 101.7 14.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM84049.1 - 3.4e-05 22.2 1.6 3.4e-05 22.2 1.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LysM PF01476.15 EIM84050.1 - 6e-15 54.8 0.1 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 LysM domain GF_recep_IV PF14843.1 EIM84050.1 - 0.023 14.3 2.3 0.027 14.0 1.6 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV EGF_3 PF12947.2 EIM84050.1 - 0.45 10.5 4.1 1.6 8.7 0.2 2.6 2 1 0 2 2 2 0 EGF domain FAD_binding_3 PF01494.14 EIM84051.1 - 1.5e-11 43.9 0.2 3e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain WD40 PF00400.27 EIM84053.1 - 3.1e-152 489.7 30.5 5e-14 51.5 0.0 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 EIM84053.1 - 1.4e-12 46.9 2.2 0.12 10.9 0.0 7.1 3 1 4 9 9 9 4 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 EIM84053.1 - 8.3e-12 44.0 18.3 0.0013 17.1 0.2 6.1 1 1 5 7 7 7 7 Cytochrome D1 heme domain NACHT PF05729.7 EIM84053.1 - 8.4e-08 32.0 0.0 2.2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF3312 PF11768.3 EIM84053.1 - 1.2e-06 27.0 0.5 7 4.7 0.0 6.7 3 2 4 9 9 9 3 Protein of unknown function (DUF3312) AAA_16 PF13191.1 EIM84053.1 - 2.4e-05 24.4 0.0 0.00023 21.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.1 EIM84053.1 - 0.0011 19.1 22.6 40 4.6 0.0 10.3 6 3 5 11 11 11 0 PQQ-like domain NB-ARC PF00931.17 EIM84053.1 - 0.0012 17.7 0.0 0.0031 16.4 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EIM84053.1 - 0.0062 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM84053.1 - 0.035 14.2 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 EIM84054.1 - 1.6e-64 218.1 0.0 8.3e-63 212.5 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EIM84055.1 - 2.8e-27 95.7 0.1 2.7e-16 59.6 0.7 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM84055.1 - 0.063 13.7 1.4 4.3 7.8 0.3 3.1 2 1 0 2 2 2 0 Aspartyl protease Fungal_trans PF04082.13 EIM84057.1 - 6.5e-23 80.9 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM84057.1 - 1.7e-09 37.3 11.1 3.4e-09 36.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.2 EIM84059.1 - 0.99 9.1 5.5 5.1 6.8 0.1 3.6 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Hydrolase PF00702.21 EIM84060.1 - 2.3e-14 54.3 0.1 3e-13 50.6 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIM84060.1 - 1.9e-13 50.0 0.1 1.9e-13 50.0 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EIM84060.1 - 1.7e-12 47.1 0.0 9.5e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIM84060.1 - 2.3e-12 47.4 0.1 1e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIM84060.1 - 0.0019 17.8 0.1 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4246 PF14033.1 EIM84063.1 - 2.2e-82 277.2 0.1 3.1e-82 276.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EIM84063.1 - 0.00044 20.5 0.0 0.00099 19.3 0.0 1.6 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF4246 PF14033.1 EIM84066.1 - 1.8e-190 633.8 0.0 2.1e-190 633.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EIM84066.1 - 0.0011 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase BOFC_N PF08977.5 EIM84066.1 - 0.012 15.3 0.1 0.039 13.7 0.1 1.8 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Pkinase PF00069.20 EIM84067.1 - 5.7e-60 202.6 0.0 1.9e-34 118.9 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84067.1 - 6e-31 107.4 0.0 1.7e-15 56.7 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EIM84067.1 - 9.9e-21 74.0 6.2 8.8e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 EIM84067.1 - 1.7e-11 43.9 0.0 4.1e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EIM84067.1 - 4.2e-08 32.6 0.0 8.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 EIM84067.1 - 0.0091 15.7 0.0 0.0091 15.7 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM84067.1 - 0.02 13.8 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like GST_N_2 PF13409.1 EIM84068.1 - 5.8e-21 74.2 0.0 1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM84068.1 - 5.8e-14 51.7 0.1 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM84068.1 - 2.8e-09 36.8 0.1 5.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM84068.1 - 2.3e-06 27.9 0.0 5.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM84068.1 - 0.00064 19.8 0.0 0.0079 16.3 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YCII PF03795.9 EIM84069.1 - 4e-08 33.3 0.0 4.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Glyco_hydro_10 PF00331.15 EIM84070.1 - 4.4e-92 308.5 0.0 5.2e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DNase_NucA_NucB PF14040.1 EIM84071.1 - 1.1e-14 54.5 0.7 5.4e-14 52.2 0.2 2.3 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB DUF4246 PF14033.1 EIM84073.1 - 4.5e-191 635.8 0.0 5.6e-191 635.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EIM84073.1 - 0.0019 18.4 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase p450 PF00067.17 EIM84075.1 - 4e-62 210.2 0.0 4.6e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84076.1 - 4.8e-59 200.1 0.0 6.1e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84077.1 - 1.9e-29 102.4 0.0 2.2e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84078.1 - 2.1e-21 76.0 0.0 2.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84079.1 - 2e-51 174.9 0.0 2.6e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84080.1 - 5.5e-60 203.2 0.0 7.6e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84081.1 - 1.7e-60 204.8 0.0 2.1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1757 PF08560.5 EIM84082.1 - 0.099 12.3 0.0 0.74 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1757) Ribosomal_S7 PF00177.16 EIM84083.1 - 4.7e-24 84.6 0.3 5.4e-24 84.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e YtpI PF14007.1 EIM84085.1 - 0.12 12.3 1.4 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 YtpI-like protein Glyco_hydro_10 PF00331.15 EIM84086.1 - 1.5e-86 290.3 0.0 1.7e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase PF00150.13 EIM84086.1 - 0.0073 15.5 0.0 0.015 14.5 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Alpha-amylase PF00128.19 EIM84087.1 - 4.1e-21 75.7 0.1 6.8e-21 74.9 0.1 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIM84087.1 - 2.4e-08 33.9 0.0 6.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Sugar_tr PF00083.19 EIM84088.1 - 2.6e-107 359.2 17.9 3.1e-107 358.9 12.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84088.1 - 1.9e-17 63.0 35.8 1.2e-16 60.3 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM84088.1 - 2.2e-05 23.0 0.9 2.2e-05 23.0 0.6 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein DUF791 PF05631.9 EIM84088.1 - 4.2e-05 22.4 0.5 4.2e-05 22.4 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Phage_holin_2 PF04550.7 EIM84088.1 - 0.03 14.3 0.4 0.084 12.9 0.3 1.8 1 0 0 1 1 1 0 Phage holin family 2 MFS_3 PF05977.8 EIM84088.1 - 0.35 8.9 6.9 0.04 12.0 1.7 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector RNase_H PF00075.19 EIM84089.1 - 1.9e-25 89.6 0.0 3.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM84089.1 - 6.2e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIM84090.1 - 1.2e-05 24.7 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAGK_cat PF00781.19 EIM84091.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PAT1 PF09770.4 EIM84091.1 - 0.29 9.3 50.1 0.38 8.9 34.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EIM84091.1 - 1.7 8.5 18.9 2.2 8.1 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EIM84091.1 - 5.6 6.2 44.4 8.7 5.6 30.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF1857 PF08982.6 EIM84092.1 - 1e-25 90.0 0.0 1.2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Cu-oxidase PF00394.17 EIM84093.1 - 9.6e-50 168.5 0.1 1.6e-44 151.6 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM84093.1 - 2e-39 134.2 7.3 9.4e-37 125.5 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM84093.1 - 1.5e-38 131.1 2.4 3.1e-37 126.9 0.5 2.9 3 0 0 3 3 3 1 Multicopper oxidase NAD_binding_10 PF13460.1 EIM84094.1 - 1.5e-13 51.1 0.2 4.9e-13 49.4 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM84094.1 - 1.4e-08 34.4 0.1 2e-08 33.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84094.1 - 2.3e-07 30.3 0.1 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EIM84094.1 - 9.6e-06 24.8 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EIM84094.1 - 0.0017 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EIM84094.1 - 0.0017 17.0 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIM84094.1 - 0.012 15.5 0.2 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EIM84094.1 - 0.015 15.0 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EIM84094.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1857 PF08982.6 EIM84096.1 - 6.9e-26 90.6 0.0 7.8e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) 4HBT PF03061.17 EIM84098.1 - 3.5e-08 33.4 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Alpha-amylase PF00128.19 EIM84100.1 - 3.3e-17 62.8 0.3 4.5e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIM84100.1 - 7.9e-10 38.7 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Thaumatin PF00314.12 EIM84101.1 - 2.6e-65 219.8 12.9 2.9e-65 219.7 8.9 1.0 1 0 0 1 1 1 1 Thaumatin family Pro_isomerase PF00160.16 EIM84105.1 - 4.5e-40 137.4 0.0 5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Leader_CPA1 PF08252.6 EIM84105.1 - 0.064 12.5 0.8 0.13 11.5 0.6 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Xpo1 PF08389.7 EIM84107.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Exportin 1-like protein DUF159 PF02586.9 EIM84108.1 - 3.3e-30 105.1 0.0 4.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 LepA_C PF06421.7 EIM84108.1 - 0.14 12.0 0.3 0.95 9.4 0.1 2.0 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus DUF159 PF02586.9 EIM84109.1 - 8.2e-20 71.2 0.0 5e-16 58.8 0.0 2.2 1 1 1 2 2 2 2 Uncharacterised ACR, COG2135 SSP160 PF06933.6 EIM84109.1 - 0.15 9.9 11.4 0.2 9.5 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Atrophin-1 PF03154.10 EIM84109.1 - 0.32 9.0 23.2 0.41 8.7 16.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family SOG2 PF10428.4 EIM84109.1 - 0.54 8.8 10.1 0.66 8.5 7.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 EIM84109.1 - 3 7.1 18.9 3.8 6.8 13.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF822 PF05687.8 EIM84109.1 - 5.4 7.3 8.7 8.5 6.7 6.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Macoilin PF09726.4 EIM84109.1 - 7.8 4.6 9.8 9.4 4.3 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein F-box-like PF12937.2 EIM84110.1 - 4.6e-07 29.4 0.1 3.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like PilO PF04350.8 EIM84110.1 - 0.15 11.9 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO DnaJ PF00226.26 EIM84111.1 - 3.3e-12 45.9 0.0 8e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CBM_5_12 PF02839.9 EIM84114.1 - 1.1e-13 50.5 5.3 3.9e-13 48.7 3.6 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain ERCC4 PF02732.10 EIM84115.1 - 3.6e-27 94.8 0.0 7.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain AAA PF00004.24 EIM84116.1 - 4.6e-17 62.4 0.0 1e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIM84116.1 - 1.4e-05 24.7 1.7 2.5e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 EIM84116.1 - 5.9e-05 23.2 0.8 0.0013 18.8 0.4 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM84116.1 - 0.00013 21.6 0.3 0.00084 19.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EIM84116.1 - 0.0034 16.9 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM84116.1 - 0.0039 16.7 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM84116.1 - 0.02 14.9 1.2 0.068 13.1 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EIM84116.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.3 EIM84116.1 - 0.035 13.9 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Mg_chelatase PF01078.16 EIM84116.1 - 0.063 12.4 0.7 0.2 10.8 0.5 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIM84116.1 - 0.067 14.0 0.1 0.21 12.3 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EIM84116.1 - 0.32 10.9 1.4 1.6 8.7 0.1 2.8 3 2 1 4 4 4 0 AAA domain Germane PF10646.4 EIM84117.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Sporulation and spore germination Git3 PF11710.3 EIM84117.1 - 2.5 7.6 14.3 7.6 6.0 9.0 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 RCC1 PF00415.13 EIM84118.1 - 1.6e-36 124.3 11.2 2.6e-07 30.7 0.0 7.8 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM84118.1 - 9.1e-19 66.5 29.1 3.8e-08 32.7 0.5 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L7Ae PF01248.21 EIM84120.1 - 3.9e-21 74.3 1.0 7.2e-21 73.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.11 EIM84122.1 - 2.7e-42 144.7 25.3 2.7e-42 144.7 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM84122.1 - 1.6e-17 63.2 8.7 1.6e-17 63.2 6.0 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIM84122.1 - 5.6e-05 21.5 3.2 5.6e-05 21.5 2.2 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EIM84123.1 - 8.3e-15 55.0 0.2 1.5e-14 54.2 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84123.1 - 3.4e-07 30.2 0.0 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM84123.1 - 5.1e-07 29.8 0.2 9.8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM84123.1 - 1.3e-05 24.9 0.1 2.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM84123.1 - 2.4e-05 23.8 0.1 0.0001 21.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84123.1 - 0.0015 17.7 0.1 0.003 16.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIM84123.1 - 0.016 14.1 0.0 0.056 12.3 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 EIM84123.1 - 0.05 13.6 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EIM84123.1 - 0.097 11.3 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 EIM84124.1 - 1.7e-58 198.2 0.0 2.5e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.20 EIM84125.1 - 8.7e-32 109.1 4.4 4e-11 43.0 0.3 3.5 3 0 0 3 3 3 3 Phosphopantetheine attachment site PS-DH PF14765.1 EIM84125.1 - 4.8e-21 75.1 0.0 7.6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIM84125.1 - 5.1e-19 69.4 0.1 1.6e-16 61.2 0.1 3.1 3 1 0 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.2 EIM84125.1 - 5.5e-06 26.4 0.1 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM84125.1 - 0.0054 16.4 0.1 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EIM84126.1 - 2.3e-48 164.4 0.0 2.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ketoacyl-synt PF00109.21 EIM84127.1 - 2.3e-77 259.9 0.0 4.7e-77 258.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIM84127.1 - 4.8e-52 177.2 0.1 3.1e-50 171.3 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EIM84127.1 - 8.9e-37 125.5 0.4 3.1e-36 123.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EIM84127.1 - 5e-36 122.7 1.7 8e-12 45.2 0.0 4.2 4 0 0 4 4 4 3 Phosphopantetheine attachment site PS-DH PF14765.1 EIM84127.1 - 6.2e-25 87.9 0.1 1.5e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIM84127.1 - 2.6e-21 76.9 0.0 4.2e-20 72.9 0.0 2.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EIM84127.1 - 3.4e-06 27.0 0.0 3.4e-06 27.0 0.0 3.3 4 0 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM84127.1 - 3.1e-05 23.7 0.2 0.038 13.7 0.0 3.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EIM84127.1 - 0.0017 17.4 0.4 0.0042 16.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain GMC_oxred_N PF00732.14 EIM84128.1 - 4.7e-66 222.9 0.0 6e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84128.1 - 2.8e-31 108.7 0.1 4.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EIM84128.1 - 0.0024 17.8 0.0 0.0072 16.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM84128.1 - 0.0025 16.8 0.2 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM84128.1 - 0.013 15.4 1.5 0.03 14.3 1.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM84128.1 - 0.026 13.3 1.3 1.2 7.8 0.8 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EIM84128.1 - 0.045 12.8 0.1 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.20 EIM84129.1 - 7.7e-21 74.7 0.2 1.7e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM84129.1 - 9.3e-10 38.4 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM84129.1 - 2.6e-05 24.1 0.0 5.5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM84129.1 - 6.8e-05 22.4 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM84129.1 - 0.00013 22.0 0.2 0.00041 20.4 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIM84129.1 - 0.0079 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CutC PF03932.9 EIM84129.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 CutC family Shikimate_DH PF01488.15 EIM84129.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UbiA PF01040.13 EIM84130.1 - 9.6e-26 90.5 15.2 1.8e-25 89.6 10.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Polyketide_cyc2 PF10604.4 EIM84131.1 - 1.2e-08 35.2 0.0 1.7e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EIM84131.1 - 2.6e-06 27.4 0.1 3.7e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 EIM84131.1 - 0.0084 15.7 0.1 2.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Carbon monoxide dehydrogenase subunit G (CoxG) AHSA1 PF08327.6 EIM84131.1 - 0.021 14.8 0.2 0.037 14.1 0.1 1.5 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein AMP-binding PF00501.23 EIM84132.1 - 7.3e-33 113.5 0.0 1e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM84132.1 - 1.1e-24 86.7 0.0 1.8e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM84132.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM84132.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIM84132.1 - 0.072 13.0 0.1 0.46 10.3 0.0 2.5 2 1 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM84132.1 - 0.09 11.6 0.0 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.15 EIM84132.1 - 0.094 12.8 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIM84132.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HTH_3 PF01381.17 EIM84132.1 - 0.21 11.4 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_19 PF12844.2 EIM84132.1 - 0.29 11.2 0.0 0.65 10.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EIM84133.1 - 2e-67 227.7 0.0 2.2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84134.1 - 5.9e-58 196.4 0.0 1e-56 192.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EIM84135.1 - 1.8e-17 63.3 0.0 2.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84135.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM84135.1 - 0.002 17.8 3.5 0.64 9.7 0.5 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM84135.1 - 0.0034 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM84135.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family p450 PF00067.17 EIM84136.1 - 3.3e-61 207.2 0.0 4.2e-60 203.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF917 PF06032.7 EIM84142.1 - 4.7e-89 298.3 0.1 7.4e-89 297.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EIM84142.1 - 3.5e-13 49.3 5.4 1.1e-11 44.4 1.5 2.9 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase PNRC PF15365.1 EIM84142.1 - 0.0027 17.6 0.8 0.0071 16.3 0.5 1.7 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator Alpha_GJ PF03229.8 EIM84142.1 - 2.6 8.3 6.6 6.4 7.1 4.6 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J Utp14 PF04615.8 EIM84149.1 - 5.4 5.0 19.5 0.047 11.8 8.1 1.4 2 0 0 2 2 2 0 Utp14 protein OTT_1508_deam PF14441.1 EIM84150.1 - 1.3e-05 25.0 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF917 PF06032.7 EIM84151.1 - 9.7e-98 326.9 0.2 1.5e-97 326.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EIM84151.1 - 1.3e-42 145.8 11.1 2e-42 145.2 3.8 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM84151.1 - 9.6e-32 109.8 3.5 1.2e-31 109.5 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIM84151.1 - 4.5e-05 21.9 0.6 0.021 13.1 0.2 2.7 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EIM84151.1 - 0.0033 16.4 1.9 0.62 8.9 0.0 2.7 3 0 0 3 3 3 2 StbA protein DUF2205 PF10224.4 EIM84153.1 - 0.033 13.7 0.7 2.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Nuc_N PF14448.1 EIM84153.1 - 0.07 12.6 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Nuclease N terminal DIOX_N PF14226.1 EIM84154.1 - 7.7e-24 84.4 0.0 1.6e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM84154.1 - 3.2e-19 69.0 0.0 5.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EIM84155.1 - 2.1e-84 283.6 33.3 2.7e-84 283.2 23.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-MYND PF01753.13 EIM84156.1 - 4.2e-09 36.1 13.0 4.2e-09 36.1 9.0 1.7 2 0 0 2 2 2 1 MYND finger DUF3039 PF11238.3 EIM84156.1 - 0.047 13.1 4.6 0.23 10.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) CBM_5_12 PF02839.9 EIM84159.1 - 1.5e-11 43.6 10.8 1.5e-11 43.6 7.5 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain Herpes_gE PF02480.11 EIM84160.1 - 0.0013 17.0 0.0 0.002 16.4 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EIM84160.1 - 0.0088 15.6 0.5 0.019 14.5 0.3 1.5 1 0 0 1 1 1 1 Syndecan domain VPEP PF07589.6 EIM84160.1 - 0.68 9.9 5.1 1.5 8.8 3.5 1.6 1 0 0 1 1 1 0 PEP-CTERM motif Aminotran_1_2 PF00155.16 EIM84162.1 - 7.2e-11 41.6 0.0 9.1e-09 34.7 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Peptidase_C14 PF00656.17 EIM84163.1 - 5.2e-06 26.3 0.0 6.6e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Caspase domain PHD PF00628.24 EIM84165.1 - 0.00038 20.0 6.6 0.00038 20.0 4.6 2.4 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EIM84165.1 - 0.0072 16.1 3.9 0.0072 16.1 2.7 3.0 4 0 0 4 4 4 1 Ring finger domain C1_1 PF00130.17 EIM84165.1 - 0.0073 16.0 0.9 0.024 14.3 0.6 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4503 PF14951.1 EIM84165.1 - 0.15 10.2 0.2 0.26 9.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) NUDIX PF00293.23 EIM84166.1 - 1.5e-09 37.6 0.1 1.9e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain GrpE PF01025.14 EIM84166.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 GrpE adh_short PF00106.20 EIM84167.1 - 1.1e-11 44.8 0.4 2.8e-11 43.6 0.0 1.9 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EIM84167.1 - 8.2e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Dor1 PF04124.7 EIM84168.1 - 1.4e-48 165.1 0.0 6.4e-47 159.6 0.0 2.7 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 EIM84168.1 - 0.00095 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 EIM84168.1 - 0.0014 18.5 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EIM84168.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Vps51/Vps67 Gly-zipper_Omp PF13488.1 EIM84169.1 - 0.0064 16.1 0.3 0.0096 15.5 0.2 1.2 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 EIM84169.1 - 0.023 14.1 0.3 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Glyco_hydro_7 PF00840.15 EIM84171.1 - 3.3e-207 688.0 20.9 5.4e-207 687.3 14.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EIM84171.1 - 3.2e-12 45.8 14.6 3.2e-12 45.8 10.1 4.5 5 0 0 5 5 5 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.11 EIM84172.1 - 2.4e-28 98.8 2.2 4.1e-28 98.1 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.13 EIM84172.1 - 2.3e-13 49.5 13.4 2.3e-13 49.5 9.3 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.11 EIM84173.1 - 5.5e-26 91.2 1.0 5.5e-26 91.2 0.7 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 12 CBM_1 PF00734.13 EIM84173.1 - 2.6e-14 52.5 9.7 2.6e-14 52.5 6.8 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.11 EIM84174.1 - 2.4e-27 95.6 2.4 4.4e-27 94.7 1.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 GMC_oxred_N PF00732.14 EIM84175.1 - 1.2e-19 70.6 0.0 2.1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84175.1 - 4.5e-19 69.1 0.3 1.3e-18 67.6 0.2 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EIM84175.1 - 5.8e-07 28.7 0.2 0.0027 16.6 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM84175.1 - 6.1e-07 28.6 0.1 1.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EIM84175.1 - 6.3e-05 22.2 0.0 0.00017 20.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM84175.1 - 0.00024 21.0 0.4 0.00066 19.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM84175.1 - 0.00026 19.5 0.1 0.00041 18.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIM84175.1 - 0.00082 18.5 0.2 0.019 14.0 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EIM84175.1 - 0.0021 17.1 0.1 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM84175.1 - 0.0022 17.8 0.1 0.0065 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM84175.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM84175.1 - 0.18 10.6 0.3 0.4 9.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A AA_permease_2 PF13520.1 EIM84176.1 - 7e-64 215.9 29.4 8.6e-64 215.6 20.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3735 PF12537.3 EIM84176.1 - 0.021 14.8 0.1 0.061 13.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) DUF2839 PF10999.3 EIM84176.1 - 0.04 13.9 0.9 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) zf-C2HC_2 PF13913.1 EIM84177.1 - 0.18 11.4 0.0 0.18 11.4 0.0 3.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type MULE PF10551.4 EIM84178.1 - 2.6e-09 37.1 0.1 7.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM84178.1 - 0.044 13.2 0.3 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 SWIM zinc finger EIF4E-T PF10477.4 EIM84179.1 - 0.0047 15.7 0.7 0.0056 15.5 0.5 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Rap_GAP PF02145.10 EIM84183.1 - 3.9e-47 160.0 0.0 6.1e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EIM84183.1 - 1.6e-26 93.2 0.1 1.6e-26 93.2 0.1 1.6 2 0 0 2 2 2 1 Tuberin XPG_I PF00867.13 EIM84184.1 - 1.4e-20 73.1 0.0 3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIM84184.1 - 0.00094 19.4 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain PBP1_TM PF14812.1 EIM84184.1 - 4.5 7.6 8.1 1.8 8.8 1.4 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.15 EIM84185.1 - 1.3e-267 888.5 5.0 1.5e-267 888.4 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM84185.1 - 4.3e-17 61.7 0.6 2.6e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIM84185.1 - 0.002 17.0 1.2 0.045 12.5 0.3 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EIM84185.1 - 0.021 13.9 4.1 0.063 12.3 0.2 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Spectrin PF00435.16 EIM84185.1 - 1.2 9.4 8.5 7.7 6.8 0.4 3.2 2 1 0 3 3 3 0 Spectrin repeat FtsA PF14450.1 EIM84185.1 - 2 8.2 6.0 14 5.5 0.2 3.6 2 1 0 2 2 2 0 Cell division protein FtsA DUF89 PF01937.14 EIM84187.1 - 1.1e-105 353.3 0.0 1.4e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acetyltransf_1 PF00583.19 EIM84188.1 - 1.7e-16 59.9 0.0 2.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM84188.1 - 3.1e-09 36.9 0.0 4.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM84188.1 - 6.4e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM84188.1 - 9.3e-08 32.0 0.0 1.5e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM84188.1 - 2.9e-07 30.1 0.1 5.1e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EIM84188.1 - 4.8e-06 26.7 0.0 8.7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM84188.1 - 8.1e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM84188.1 - 0.00042 20.3 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM84188.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F-box-like PF12937.2 EIM84189.1 - 7.6e-07 28.7 0.2 2.4e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.13 EIM84191.1 - 2.3e-56 187.7 13.4 3.8e-10 39.8 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM84191.1 - 1.1e-30 104.5 43.9 5.5e-08 32.2 0.4 7.2 8 1 1 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 EIM84191.1 - 0.36 10.6 2.3 1.3 8.7 0.0 2.9 4 1 0 4 4 4 0 SUKH-3 immunity protein COesterase PF00135.23 EIM84192.1 - 3.4e-95 319.7 0.0 4.1e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM84192.1 - 6.8e-06 25.8 1.3 4.1e-05 23.2 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM84192.1 - 0.019 13.6 0.0 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) MFS_1 PF07690.11 EIM84193.1 - 6.2e-28 97.5 32.5 7.7e-28 97.2 22.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 EIM84193.1 - 0.031 14.2 0.4 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MFS_1 PF07690.11 EIM84194.1 - 1.4e-30 106.2 29.8 1.6e-30 106.0 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 EIM84194.1 - 0.0023 17.8 0.5 0.012 15.6 0.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) NST1 PF13945.1 EIM84195.1 - 2.1e-55 187.7 9.0 2.1e-55 187.7 6.2 5.2 3 2 2 5 5 5 3 Salt tolerance down-regulator E1-E2_ATPase PF00122.15 EIM84196.1 - 1.9e-22 79.4 0.0 1.9e-22 79.4 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIM84196.1 - 8.3e-16 59.0 0.0 2.2e-14 54.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM84196.1 - 4.2e-11 43.3 0.1 9.6e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM84196.1 - 2.4e-05 24.2 0.0 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIM84196.1 - 2.7e-05 23.8 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zinc_ribbon_5 PF13719.1 EIM84197.1 - 0.017 14.6 1.3 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM84197.1 - 0.051 13.2 1.3 10 5.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.1 EIM84197.1 - 0.053 13.4 0.3 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 CpXC protein Ribosomal_L12 PF00542.14 EIM84197.1 - 0.12 12.4 4.5 0.68 9.9 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain LsmAD PF06741.8 EIM84197.1 - 2.6 8.2 5.5 5.6 7.1 3.8 1.5 1 0 0 1 1 1 0 LsmAD domain F-box-like PF12937.2 EIM84200.1 - 1e-11 44.3 0.5 2.3e-11 43.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like DUF605 PF04652.11 EIM84200.1 - 4.1 6.6 8.0 5.8 6.1 5.6 1.1 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 EIM84202.1 - 6.6e-90 301.8 19.7 7.7e-90 301.6 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84202.1 - 8.7e-26 90.4 41.0 5e-14 51.7 12.2 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM84202.1 - 0.0067 14.6 3.7 0.013 13.7 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EIM84202.1 - 0.0091 15.9 7.7 0.16 11.9 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Abhydrolase_3 PF07859.8 EIM84203.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold GATA PF00320.22 EIM84204.1 - 7.3e-26 89.2 19.1 1.6e-15 56.1 1.9 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EIM84204.1 - 8.7e-11 41.1 0.3 2.2e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zinc_ribbon_5 PF13719.1 EIM84204.1 - 0.13 11.8 2.8 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIM84204.1 - 0.21 11.3 3.7 1.5 8.6 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EIM84204.1 - 0.34 10.2 7.8 0.16 11.3 0.9 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EIM84204.1 - 0.78 9.7 5.7 6.9 6.7 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EIM84204.1 - 1.1 9.3 6.2 0.076 13.0 0.3 2.1 2 0 0 2 2 2 0 zinc-finger eIF-5_eIF-2B PF01873.12 EIM84204.1 - 2.8 7.6 8.3 5.9 6.5 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CHZ PF09649.5 EIM84205.1 - 4.7e-13 48.1 0.1 4.7e-13 48.1 0.1 2.5 3 1 0 3 3 3 1 Histone chaperone domain CHZ Neur_chan_memb PF02932.11 EIM84205.1 - 0.12 12.2 9.0 0.18 11.6 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FCP1_C PF09309.5 EIM84205.1 - 6.3 6.0 28.5 2.8 7.1 1.8 2.1 2 0 0 2 2 2 0 FCP1, C-terminal zf-C2H2_jaz PF12171.3 EIM84206.1 - 2.9e-15 55.9 30.3 0.0004 20.4 0.6 7.2 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIM84206.1 - 3e-13 49.0 32.3 0.12 12.7 0.0 7.5 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM84206.1 - 1.7e-10 40.5 35.3 0.1 12.9 0.2 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIM84206.1 - 6.8e-09 35.7 18.8 0.0012 18.9 1.0 5.6 2 2 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIM84206.1 - 1.2e-08 34.8 22.8 0.15 12.2 0.1 6.7 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EIM84206.1 - 0.0026 17.9 2.6 0.11 12.8 0.2 6.7 7 0 0 7 7 7 2 Zinc-finger double domain Rad50_zn_hook PF04423.9 EIM84206.1 - 0.0059 16.0 5.8 6.7 6.2 0.1 4.5 3 1 1 4 4 4 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.1 EIM84206.1 - 0.016 15.0 31.5 1.3 9.0 0.1 7.2 7 1 0 7 7 7 0 C2H2-type zinc finger zf-Di19 PF05605.7 EIM84206.1 - 0.051 13.6 22.1 0.19 11.8 1.4 4.8 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_2 PF12674.2 EIM84206.1 - 0.07 13.4 0.0 0.07 13.4 0.0 2.6 3 1 0 3 3 2 0 Putative zinc ribbon domain zf-C2HC_2 PF13913.1 EIM84206.1 - 0.26 11.0 18.3 1.1 8.9 0.3 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Mob_synth_C PF06463.8 EIM84206.1 - 0.39 10.4 0.1 0.39 10.4 0.0 3.3 2 1 2 4 4 4 0 Molybdenum Cofactor Synthesis C Tmpp129 PF10272.4 EIM84206.1 - 0.46 9.1 4.7 0.44 9.2 0.6 2.2 2 0 0 2 2 2 0 Putative transmembrane protein precursor zinc_ribbon_5 PF13719.1 EIM84206.1 - 1.4 8.5 15.8 3.4 7.3 0.1 4.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIM84206.1 - 1.6 8.0 10.3 20 4.5 0.4 4.5 4 0 0 4 4 4 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 EIM84206.1 - 3.9 7.5 8.9 2.2 8.4 0.9 3.0 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EIM84206.1 - 7.4 6.4 21.3 9.5 6.1 1.7 4.6 3 2 0 3 3 3 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EIM84206.1 - 9.4 5.9 23.7 8.1 6.2 1.1 4.3 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.2 EIM84207.1 - 4.7e-06 26.2 0.5 1.3e-05 24.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like AIRC PF00731.15 EIM84209.1 - 6.3e-63 210.5 1.4 1.7e-62 209.1 0.7 2.0 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 EIM84209.1 - 1.7e-59 200.0 0.0 2.6e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EIM84209.1 - 1.1e-10 41.5 0.0 2.9e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EIM84209.1 - 1.3e-07 31.1 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EIM84209.1 - 0.00012 20.9 0.0 0.0015 17.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EIM84209.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EIM84209.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ABA_GPCR PF12430.3 EIM84211.1 - 2e-28 98.8 0.0 2e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EIM84211.1 - 1.6e-12 47.3 0.0 4.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) E1-E2_ATPase PF00122.15 EIM84211.1 - 1.8 7.5 6.5 2.5 7.0 4.0 1.6 1 1 0 1 1 1 0 E1-E2 ATPase NAD_binding_10 PF13460.1 EIM84212.1 - 1e-16 61.5 0.1 1.4e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 EIM84214.1 - 4.2e-35 121.1 48.0 9.2e-35 119.9 31.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM84214.1 - 5.2e-22 77.7 21.6 6.6e-22 77.4 14.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM84214.1 - 1.2e-10 40.5 16.1 1.2e-10 40.5 11.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1212 PF06738.7 EIM84214.1 - 0.14 11.6 15.3 0.026 13.9 3.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1212) Mpv17_PMP22 PF04117.7 EIM84214.1 - 0.26 10.9 3.6 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Mpv17 / PMP22 family HlyIII PF03006.15 EIM84214.1 - 1.7 8.0 22.1 0.023 14.1 3.4 4.1 2 2 2 4 4 4 0 Haemolysin-III related adh_short PF00106.20 EIM84215.1 - 4.7e-26 91.6 0.6 6.2e-26 91.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84215.1 - 1e-10 41.8 0.0 1.3e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM84215.1 - 8.7e-05 22.2 0.5 0.00021 21.0 0.3 1.6 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EIM84215.1 - 0.00041 19.8 0.6 0.0032 17.0 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 EIM84215.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM84215.1 - 0.0059 16.6 0.5 0.014 15.3 0.4 2.0 1 1 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 EIM84215.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Acyl-CoA_dh_M PF02770.14 EIM84216.1 - 0.0023 17.3 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIM84216.1 - 0.0034 17.4 0.9 0.0066 16.5 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.17 EIM84217.1 - 5.4e-67 226.2 0.0 7.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.9 EIM84218.1 - 5.7e-27 94.9 0.1 3.6e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Kdo PF06293.9 EIM84222.1 - 0.012 14.6 0.1 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF1G PF00647.14 EIM84223.1 - 3.7e-41 139.1 0.0 6.9e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EIM84223.1 - 1.9e-09 37.3 0.3 5.6e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM84223.1 - 7.3e-08 32.1 0.1 2.1e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM84223.1 - 3.1e-05 24.3 0.0 8.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM84223.1 - 0.00078 19.5 0.0 0.028 14.5 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain VAD1-2 PF15310.1 EIM84223.1 - 0.024 14.3 2.1 0.038 13.6 1.5 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Rotamase PF00639.16 EIM84223.1 - 0.08 13.6 0.6 1.1 10.0 0.0 2.4 1 1 1 2 2 2 0 PPIC-type PPIASE domain MAP1B_neuraxin PF00414.12 EIM84223.1 - 0.48 9.8 2.1 0.41 10.0 0.1 2.0 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat zf-MYND PF01753.13 EIM84225.1 - 2.3e-09 36.9 18.5 2.3e-09 36.9 12.8 3.2 3 0 0 3 3 3 2 MYND finger Glyoxalase_2 PF12681.2 EIM84225.1 - 0.016 15.7 0.0 0.76 10.4 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain Acetyltransf_1 PF00583.19 EIM84227.1 - 2.2e-11 43.6 0.0 8e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM84227.1 - 6.9e-08 32.5 0.0 4.2e-06 26.8 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM84227.1 - 5.5e-07 29.7 0.0 8.3e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM84227.1 - 6.6e-06 26.0 0.0 0.007 16.2 0.0 2.9 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM84227.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F-box-like PF12937.2 EIM84228.1 - 1.4e-06 27.8 0.6 4.9e-06 26.1 0.4 2.0 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 EIM84228.1 - 0.22 11.0 5.6 0.42 10.1 3.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EIM84228.1 - 1.4 6.7 2.6 1.9 6.3 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 EIM84228.1 - 1.9 8.3 14.5 3.1 7.6 10.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 EIM84228.1 - 2.5 6.7 7.7 3.5 6.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_hydro_72 PF03198.9 EIM84229.1 - 2.8e-105 351.7 0.0 3.5e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EIM84229.1 - 3.2e-20 72.3 1.5 6.2e-20 71.4 1.1 1.5 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EIM84229.1 - 0.00041 19.6 0.0 0.00089 18.5 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ACOX PF01756.14 EIM84235.1 - 8e-25 87.3 0.0 1.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIM84235.1 - 6.9e-17 61.9 0.0 1.7e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIM84235.1 - 9.2e-09 34.6 0.4 3.2e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIM84235.1 - 0.00015 21.9 0.7 0.00039 20.5 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEC-1_C PF04626.8 EIM84236.1 - 0.0014 18.7 0.1 0.0033 17.5 0.1 1.6 1 0 0 1 1 1 1 Dec-1 protein, C terminal region Fes1 PF08609.5 EIM84238.1 - 3.8e-24 84.9 0.2 1e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Atx10homo_assoc PF09759.4 EIM84238.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 EIM84238.1 - 0.021 15.2 0.6 5.6 7.5 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat BCA_ABC_TP_C PF12399.3 EIM84238.1 - 0.031 13.9 1.0 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter HEAT_2 PF13646.1 EIM84238.1 - 0.14 12.4 1.4 1.1 9.5 0.1 2.8 2 1 2 4 4 4 0 HEAT repeats Acyl-CoA_dh_M PF02770.14 EIM84239.1 - 0.0046 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF829 PF05705.9 EIM84240.1 - 1.1e-29 103.8 0.0 1.3e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 EIM84241.1 - 6.2e-30 104.0 48.2 6.2e-30 104.0 33.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM84241.1 - 1.5e-23 82.9 20.6 1.7e-23 82.6 14.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM84241.1 - 2.4e-13 49.5 11.8 2.4e-13 49.5 8.1 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter p450 PF00067.17 EIM84242.1 - 1.2e-32 113.0 0.0 3.7e-29 101.5 0.0 2.3 1 1 1 2 2 2 2 Cytochrome P450 CheR PF01739.13 EIM84242.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.17 EIM84244.1 - 5.3e-07 28.5 0.0 5.3e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84245.1 - 2.6e-49 167.9 0.0 3.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_fiss_reg PF05308.6 EIM84247.1 - 0.11 11.8 2.2 0.19 11.1 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator UbiA PF01040.13 EIM84248.1 - 8.1e-26 90.7 10.7 9.6e-26 90.5 7.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GST_N_3 PF13417.1 EIM84249.1 - 3.6e-23 81.5 0.0 9.9e-23 80.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM84249.1 - 7.7e-17 61.0 0.0 1.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM84249.1 - 5.2e-08 32.9 0.0 8.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM84249.1 - 1.1e-06 28.4 0.0 5.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM84249.1 - 2.6e-05 24.1 0.3 0.00013 21.9 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM84249.1 - 0.031 14.7 0.5 0.17 12.3 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Wzy_C PF04932.10 EIM84250.1 - 2.1 8.0 10.4 0.1 12.3 2.8 1.9 1 1 1 2 2 2 0 O-Antigen ligase FAD_binding_3 PF01494.14 EIM84251.1 - 9.2e-15 54.5 0.1 1.2e-08 34.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM84251.1 - 0.08 12.9 0.1 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.2 EIM84252.1 - 0.00042 19.9 0.7 0.0018 17.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM84252.1 - 0.23 11.1 2.4 51 3.6 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Cullin_binding PF03556.10 EIM84253.1 - 6.1e-34 116.6 0.9 6.1e-34 116.6 0.7 1.5 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EIM84253.1 - 5.2e-06 25.8 0.0 1.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain F-box-like PF12937.2 EIM84254.1 - 5.1e-07 29.3 1.6 1.4e-06 27.9 1.1 1.8 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.14 EIM84255.1 - 4.5e-47 160.6 0.0 9e-29 100.5 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84255.1 - 2.2e-27 96.0 0.4 1.8e-22 80.2 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase Hc1 PF07432.8 EIM84258.1 - 0.09 12.9 0.9 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Pkinase PF00069.20 EIM84259.1 - 3.6e-06 26.3 0.0 5.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIM84259.1 - 7.2e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIM84259.1 - 0.00015 20.9 0.0 0.00052 19.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EIM84259.1 - 0.00015 21.3 0.1 0.00041 19.9 0.1 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EIM84259.1 - 0.0024 17.6 0.2 0.039 13.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EIM84259.1 - 0.0078 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EIM84259.1 - 0.034 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family BDV_G PF06208.6 EIM84259.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus G protein Kinase-like PF14531.1 EIM84259.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIM84260.1 - 0.0024 16.9 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIM84260.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Nucleoplasmin PF03066.10 EIM84260.1 - 0.28 10.6 3.0 0.39 10.2 2.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EIM84260.1 - 0.54 9.3 3.3 0.76 8.8 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.3 EIM84260.1 - 1.6 9.3 10.9 3.1 8.4 7.6 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-MYND PF01753.13 EIM84262.1 - 8.3e-09 35.1 15.5 3e-08 33.4 10.7 2.0 1 0 0 1 1 1 1 MYND finger CATSPERB PF15149.1 EIM84262.1 - 1.2 7.2 3.5 1.7 6.7 2.4 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family RepL PF05732.6 EIM84263.1 - 0.032 13.4 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) tRNA-synt_1 PF00133.17 EIM84266.1 - 4.7e-38 130.5 0.1 2.8e-28 98.2 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EIM84266.1 - 4.9e-17 61.6 0.3 8.3e-09 34.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EIM84266.1 - 1.7e-14 53.8 0.9 5.5e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EIM84266.1 - 7.7e-09 35.0 0.1 1.5e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Amidohydro_2 PF04909.9 EIM84267.1 - 2.4e-08 33.9 0.1 8.3e-08 32.1 0.0 1.7 1 1 1 2 2 2 1 Amidohydrolase F-box PF00646.28 EIM84268.1 - 1.1e-07 31.3 0.5 2.7e-07 30.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM84268.1 - 1.2e-07 31.3 0.2 2.9e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like zf-primase PF09329.6 EIM84269.1 - 1.7e-13 49.9 1.1 3.5e-13 48.9 0.8 1.6 1 0 0 1 1 1 1 Primase zinc finger Peptidase_C65 PF10275.4 EIM84270.1 - 3.5e-61 206.6 0.0 4.2e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EIM84270.1 - 1.2e-05 25.8 0.0 0.055 14.0 0.0 2.2 2 0 0 2 2 2 2 OTU-like cysteine protease PseudoU_synth_1 PF01416.15 EIM84271.1 - 1.6e-22 79.9 0.0 1.4e-12 47.9 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Oxysterol_BP PF01237.13 EIM84272.1 - 1.9e-80 270.0 1.2 1.4e-79 267.2 0.8 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein RNA_pol_Rpb2_6 PF00562.23 EIM84273.1 - 1.8e-118 395.6 0.2 2.4e-118 395.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIM84273.1 - 1.8e-55 187.0 0.1 4.4e-55 185.7 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EIM84273.1 - 7.4e-29 99.8 0.1 1.8e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EIM84273.1 - 7.4e-28 97.2 0.0 3.4e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EIM84273.1 - 2e-22 78.7 2.2 6.7e-22 77.0 1.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIM84273.1 - 3e-21 74.9 0.0 6.5e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIM84273.1 - 1.7e-14 53.5 0.2 3.6e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ALO PF04030.9 EIM84274.1 - 4.3e-78 262.4 0.9 5.3e-78 262.1 0.6 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EIM84274.1 - 9.2e-28 96.4 0.7 1.6e-27 95.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.15 EIM84275.1 - 0.00027 18.9 0.0 0.00075 17.5 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM84275.1 - 0.29 9.7 0.0 0.51 8.8 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Noc2 PF03715.8 EIM84277.1 - 5.1e-98 327.6 0.0 1.9e-95 319.1 0.0 2.5 2 0 0 2 2 2 2 Noc2p family MT-A70 PF05063.9 EIM84278.1 - 1.4e-38 132.1 0.0 3.8e-38 130.7 0.0 1.7 1 1 0 1 1 1 1 MT-A70 TPR_11 PF13414.1 EIM84279.1 - 2.2e-38 129.7 12.4 9.9e-15 53.9 3.2 5.4 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 EIM84279.1 - 6.7e-23 78.7 12.5 3.7e-05 23.3 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EIM84279.1 - 7.6e-23 79.1 7.0 2.1e-06 27.0 0.0 7.1 8 1 0 8 8 7 4 Tetratricopeptide repeat DnaJ PF00226.26 EIM84279.1 - 4.1e-19 68.0 0.3 5.6e-18 64.4 0.0 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_9 PF13371.1 EIM84279.1 - 6.4e-17 61.1 13.9 8.5e-05 22.3 0.5 4.7 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84279.1 - 5.1e-15 55.6 8.8 7.9e-07 29.5 0.5 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM84279.1 - 2.4e-13 49.4 21.5 0.00014 22.1 0.1 7.3 4 3 4 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIM84279.1 - 4.2e-13 49.4 9.5 9.3e-05 22.6 0.1 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM84279.1 - 2.1e-11 43.5 15.1 3.2e-08 33.3 1.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84279.1 - 4.7e-11 41.6 0.4 0.0015 18.1 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM84279.1 - 8.5e-07 29.0 3.4 0.00035 20.6 0.7 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIM84279.1 - 1.7e-05 24.9 0.4 0.027 14.8 0.0 5.4 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM84279.1 - 2e-05 24.0 13.1 0.0036 16.9 0.0 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM84279.1 - 0.00044 20.2 11.5 3.8 7.9 0.5 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM84279.1 - 0.00045 20.0 4.0 0.47 10.3 0.0 3.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 EIM84279.1 - 0.0017 17.1 1.5 0.38 9.4 0.0 3.3 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.1 EIM84279.1 - 0.0037 17.4 2.3 0.66 10.1 0.0 3.3 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation Apc5 PF12862.2 EIM84279.1 - 0.025 14.4 0.1 0.61 9.9 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 BAR PF03114.13 EIM84280.1 - 1.1e-33 116.7 15.5 1.8e-33 115.9 10.8 1.4 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EIM84280.1 - 3.3e-10 39.1 1.7 3.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIM84280.1 - 6e-10 38.4 0.2 1.4e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIM84280.1 - 4.2e-09 35.8 0.1 9e-09 34.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vault PF01505.13 EIM84280.1 - 0.12 12.5 0.3 26 4.9 0.0 2.7 2 0 0 2 2 2 0 Major Vault Protein repeat V_ATPase_I PF01496.14 EIM84280.1 - 0.4 8.4 9.7 0.66 7.7 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SWIB PF02201.13 EIM84281.1 - 1.7e-13 50.0 0.0 4.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain SNF2_N PF00176.18 EIM84282.1 - 3.6e-41 140.9 0.1 7.8e-24 83.9 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM84282.1 - 2.8e-16 59.1 0.0 4.6e-13 48.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain VIGSSK PF14773.1 EIM84282.1 - 6.2e-05 22.8 0.5 6.2e-05 22.8 0.3 2.5 1 1 1 2 2 2 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 EIM84282.1 - 0.083 12.7 4.3 4.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TPR_11 PF13414.1 EIM84283.1 - 5.9e-30 102.7 16.9 2.9e-12 46.0 0.6 5.9 4 3 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 EIM84283.1 - 1.9e-22 77.3 8.4 0.021 14.6 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 EIM84283.1 - 1.8e-21 74.7 12.1 0.003 17.0 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat DnaJ PF00226.26 EIM84283.1 - 4.6e-21 74.3 0.2 1.4e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.1 EIM84283.1 - 1.1e-11 44.5 19.4 8.9e-06 25.5 0.5 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIM84283.1 - 2.1e-06 27.4 9.6 0.74 9.7 0.1 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84283.1 - 5.8e-06 25.7 11.0 8.1 6.4 0.0 7.2 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM84283.1 - 6.6e-06 26.3 16.6 0.88 10.3 0.0 8.0 4 3 5 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM84283.1 - 1.2e-05 25.5 14.5 0.041 14.2 0.6 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM84283.1 - 1.2e-05 25.3 9.5 0.00075 19.5 1.8 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM84283.1 - 6.7e-05 22.3 11.8 0.89 9.5 0.0 7.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84283.1 - 0.00023 21.7 17.4 0.022 15.4 0.1 5.8 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM84283.1 - 0.00047 20.4 0.3 3.4 8.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIM84283.1 - 0.012 14.8 3.8 0.76 9.0 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR Fis1_TPR_C PF14853.1 EIM84283.1 - 0.071 12.9 5.9 0.28 11.0 0.1 3.8 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat VanW PF04294.8 EIM84283.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 VanW like protein TPR_17 PF13431.1 EIM84283.1 - 0.11 12.7 7.8 0.9 9.9 0.3 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat MIT PF04212.13 EIM84283.1 - 0.17 11.7 7.3 5.5 6.9 0.1 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain zf-CCHC PF00098.18 EIM84284.1 - 6.5e-13 47.9 22.7 5.6e-05 22.8 0.7 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EIM84284.1 - 2.8e-06 26.9 26.7 0.0021 17.7 0.5 4.5 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.1 EIM84284.1 - 0.0043 16.7 20.3 0.2 11.3 0.2 4.0 2 2 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.1 EIM84284.1 - 0.15 11.6 12.2 0.47 9.9 1.4 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger A2L_zn_ribbon PF08792.5 EIM84284.1 - 1.1 8.8 8.3 16 5.1 0.2 3.8 3 0 0 3 3 3 0 A2L zinc ribbon domain eIF3g PF12353.3 EIM84284.1 - 7.8 6.4 16.4 0.78 9.6 0.4 3.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_S19 PF00203.16 EIM84287.1 - 4e-24 84.0 0.1 5.1e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 F-box-like PF12937.2 EIM84290.1 - 1.9e-05 24.2 0.1 8.5e-05 22.2 0.1 2.2 1 0 0 1 1 1 1 F-box-like DUF2363 PF10155.4 EIM84291.1 - 4.6e-05 23.3 0.0 8.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Asn_synthase PF00733.16 EIM84292.1 - 4e-50 170.6 0.0 7.8e-50 169.7 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIM84292.1 - 3.5e-35 120.4 0.0 1.2e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIM84292.1 - 2.2e-24 85.8 0.0 5.5e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EIM84292.1 - 4.4e-06 26.0 0.0 8.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EIM84292.1 - 0.011 14.4 0.0 0.025 13.3 0.0 1.5 1 1 1 2 2 2 0 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EIM84292.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Yip1 PF04893.12 EIM84293.1 - 9.3e-05 21.9 6.3 9.3e-05 21.9 4.4 1.5 1 1 1 2 2 2 1 Yip1 domain SNARE_assoc PF09335.6 EIM84293.1 - 0.057 13.6 4.9 0.089 12.9 2.8 1.8 1 1 1 2 2 2 0 SNARE associated Golgi protein TctB PF07331.6 EIM84293.1 - 0.21 11.2 6.6 0.38 10.3 4.6 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family FtsX PF02687.16 EIM84293.1 - 1.3 8.8 11.5 0.64 9.7 0.6 2.3 2 1 0 2 2 2 0 FtsX-like permease family FUSC_2 PF13515.1 EIM84293.1 - 3 7.7 7.8 2.3 8.1 0.2 2.5 1 1 1 2 2 2 0 Fusaric acid resistance protein-like Pkinase PF00069.20 EIM84294.1 - 5.6e-74 248.5 0.4 5.6e-74 248.5 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84294.1 - 2.7e-52 177.4 0.3 2.7e-52 177.4 0.2 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIM84294.1 - 1.5e-20 73.3 0.0 4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIM84294.1 - 3.4e-06 26.2 0.0 7.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EIM84294.1 - 0.0039 17.3 0.1 0.0076 16.4 0.1 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.18 EIM84294.1 - 0.0063 16.2 4.3 0.0092 15.7 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family p450 PF00067.17 EIM84295.1 - 1.3e-62 211.8 0.0 1.6e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FolB PF02152.13 EIM84296.1 - 3.9e-09 36.6 0.1 8.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Dihydroneopterin aldolase Glucodextran_N PF09137.6 EIM84296.1 - 0.057 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain N Glyco_hydro_16 PF00722.16 EIM84297.1 - 1.3e-06 27.8 0.2 2.6e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_20 PF00982.16 EIM84298.1 - 1.2e-147 492.2 0.0 1.5e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIM84298.1 - 3.2e-24 85.1 0.0 5.5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase RdRP PF05183.7 EIM84299.1 - 3.7e-97 326.3 0.0 5.7e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Rubredoxin PF00301.15 EIM84299.1 - 0.68 9.8 3.0 4.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin UQ_con PF00179.21 EIM84300.1 - 3.7e-47 159.2 0.0 4.3e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM84300.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF1620 PF07774.8 EIM84301.1 - 1.7e-69 233.3 0.0 3e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EIM84301.1 - 2.8e-08 33.5 3.1 0.00046 19.7 0.5 3.3 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 EIM84301.1 - 6.9e-05 22.1 3.9 0.23 11.0 0.0 5.1 5 0 0 5 5 5 2 PQQ enzyme repeat US22 PF02393.11 EIM84301.1 - 0.017 15.1 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 US22 like CobA_CobO_BtuR PF02572.10 EIM84302.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DTHCT PF08070.6 EIM84302.1 - 9.2 7.0 8.8 4.9 7.8 2.4 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region STE3 PF02076.10 EIM84303.1 - 4.2e-92 308.2 11.6 4.8e-92 308.0 8.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.7 EIM84303.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Pheromone PF08015.6 EIM84304.1 - 0.00048 20.9 1.6 0.0054 17.5 1.1 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone CFEM PF05730.6 EIM84305.1 - 0.041 13.7 5.6 0.089 12.6 3.9 1.6 1 0 0 1 1 1 0 CFEM domain STE3 PF02076.10 EIM84306.1 - 2.7e-36 125.0 8.8 3.1e-36 124.9 6.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF1345 PF07077.6 EIM84306.1 - 0.00047 19.7 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) STE3 PF02076.10 EIM84307.1 - 2.1e-41 141.8 10.7 2.6e-41 141.6 7.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor p450 PF00067.17 EIM84308.1 - 4.2e-23 81.5 0.0 1.6e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84309.1 - 4.7e-51 173.7 0.0 6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PHA_gran_rgn PF09650.5 EIM84312.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) p450 PF00067.17 EIM84314.1 - 4.1e-66 223.3 0.0 4.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bombinin PF05298.6 EIM84315.1 - 0.072 12.5 0.0 8.3 5.8 0.0 2.7 3 0 0 3 3 3 0 Bombinin But2 PF09792.4 EIM84316.1 - 0.00088 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EIM84317.1 - 2.2e-23 83.0 2.8 6e-23 81.6 2.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1708 PF08101.6 EIM84319.1 - 6e-13 48.4 0.0 7.4e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EIM84319.1 - 0.024 14.2 0.0 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain INT_SG_DDX_CT_C PF15300.1 EIM84319.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sugar_tr PF00083.19 EIM84320.1 - 2e-16 59.6 22.4 1.5e-13 50.1 7.3 3.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIM84320.1 - 4.2e-16 58.6 48.0 1.2e-10 40.7 25.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.24 EIM84321.1 - 9.7e-88 291.1 0.0 4.5e-43 146.6 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM84321.1 - 9.8e-12 44.7 0.2 6.4e-07 29.1 0.0 3.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM84321.1 - 3.2e-11 43.4 0.0 8.2e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIM84321.1 - 4.3e-11 42.3 0.1 0.00043 19.3 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIM84321.1 - 1.1e-09 38.4 0.1 0.00079 19.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM84321.1 - 2.4e-09 37.4 1.8 0.00019 21.4 0.1 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 EIM84321.1 - 2.6e-09 37.0 0.0 0.00035 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIM84321.1 - 3.8e-09 36.2 0.0 9.5e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIM84321.1 - 1.7e-08 33.7 0.0 0.001 18.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EIM84321.1 - 1e-07 31.0 0.0 0.0079 14.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EIM84321.1 - 4e-07 29.6 3.6 6.8e-05 22.5 0.2 3.8 4 0 0 4 4 3 1 Part of AAA domain AAA_14 PF13173.1 EIM84321.1 - 7.9e-07 29.0 0.0 0.025 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EIM84321.1 - 1e-05 26.3 0.0 0.0034 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EIM84321.1 - 3.1e-05 24.0 0.0 0.099 12.6 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EIM84321.1 - 3.3e-05 23.3 4.8 0.097 12.0 0.0 4.1 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 EIM84321.1 - 0.00015 20.9 0.9 0.18 10.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EIM84321.1 - 0.0003 20.7 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIM84321.1 - 0.00073 19.6 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EIM84321.1 - 0.0012 18.5 0.5 0.15 11.7 0.0 3.8 4 0 0 4 4 4 1 NACHT domain Bac_DnaA PF00308.13 EIM84321.1 - 0.0027 17.3 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.1 EIM84321.1 - 0.004 16.7 0.0 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIM84321.1 - 0.004 16.7 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.11 EIM84321.1 - 0.0045 15.8 0.1 0.32 9.7 0.0 2.8 4 0 0 4 4 4 1 AFG1-like ATPase Sigma54_activat PF00158.21 EIM84321.1 - 0.005 16.3 0.0 1.9 7.9 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 EIM84321.1 - 0.0061 15.8 0.4 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.1 EIM84321.1 - 0.0062 16.8 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EIM84321.1 - 0.007 15.8 0.0 0.97 8.8 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ParA PF10609.4 EIM84321.1 - 0.011 15.5 0.0 4.7 7.1 0.0 3.0 2 0 0 2 2 2 0 ParA/MinD ATPase like DAP3 PF10236.4 EIM84321.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 EIM84321.1 - 0.015 15.5 0.0 0.45 10.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.13 EIM84321.1 - 0.021 14.3 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EIM84321.1 - 0.023 14.2 0.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EIM84321.1 - 0.032 12.9 0.0 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EIM84321.1 - 0.058 13.1 0.1 1.5 8.4 0.0 2.9 2 1 1 3 3 3 0 NTPase AAA_30 PF13604.1 EIM84321.1 - 0.074 12.6 0.2 0.21 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 EIM84321.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EIM84321.1 - 0.11 11.6 0.1 11 5.0 0.0 2.5 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.12 EIM84321.1 - 0.13 11.1 0.0 0.45 9.3 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AKAP7_NLS PF10469.4 EIM84322.1 - 1.1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain p450 PF00067.17 EIM84323.1 - 7.9e-60 202.6 0.0 9.3e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84324.1 - 9.9e-52 175.9 0.0 1.3e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4488 PF14869.1 EIM84324.1 - 0.13 11.8 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) 4HBT_2 PF13279.1 EIM84325.1 - 1.9e-15 57.3 0.0 3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EIM84325.1 - 1.3e-07 31.5 0.0 4.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EIM84325.1 - 0.00083 18.3 0.0 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase RRM_1 PF00076.17 EIM84326.1 - 8.6e-77 252.7 0.1 1.6e-19 69.3 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM84326.1 - 3.6e-58 193.4 0.1 5.5e-14 51.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM84326.1 - 9.4e-30 102.2 0.0 2.7e-06 27.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM84326.1 - 9.1e-05 22.1 0.0 3.7 7.3 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIM84326.1 - 0.00017 21.4 0.0 0.41 10.5 0.0 5.1 5 1 0 5 5 5 1 RNA binding motif RRM_2 PF04059.7 EIM84326.1 - 0.0025 17.8 0.0 5.7 7.0 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif 2 SNF2_N PF00176.18 EIM84327.1 - 3.1e-41 141.1 0.0 5.8e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EIM84327.1 - 3.9e-07 29.7 11.7 7e-07 28.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM84327.1 - 2.7e-06 26.9 9.7 4.5e-06 26.2 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM84327.1 - 3.1e-06 27.0 13.0 5.9e-06 26.2 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM84327.1 - 6.5e-05 22.5 12.3 0.00011 21.7 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM84327.1 - 0.00013 21.5 12.0 0.00022 20.8 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIM84327.1 - 0.0056 16.4 1.4 0.012 15.3 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EIM84327.1 - 0.0092 15.5 6.1 0.022 14.2 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EIM84327.1 - 0.013 15.5 9.8 0.046 13.8 6.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EIM84327.1 - 0.37 10.5 3.9 0.81 9.5 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EIM84327.1 - 0.82 9.5 11.3 1.7 8.6 7.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EIM84327.1 - 1.8 8.1 6.0 4.9 6.7 3.8 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EIM84327.1 - 2.3 8.0 6.9 6.1 6.6 4.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 EIM84328.1 - 0.0014 16.6 12.3 0.0032 15.4 8.5 1.5 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.7 EIM84328.1 - 1.4 8.0 10.2 2.9 7.0 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EIM84328.1 - 2.4 7.6 15.4 4.6 6.7 10.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Spt20 PF12090.3 EIM84328.1 - 3.8 6.8 12.6 0.28 10.5 0.8 3.1 3 0 0 3 3 3 0 Spt20 family Myb_DNA-binding PF00249.26 EIM84329.1 - 2.5e-17 62.6 0.1 3.1e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM84329.1 - 2.6e-13 49.8 0.0 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SRA1 PF07304.6 EIM84329.1 - 0.51 10.0 3.9 0.46 10.1 1.6 1.7 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF3439 PF11921.3 EIM84329.1 - 7.1 6.4 12.6 14 5.4 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PCI PF01399.22 EIM84330.1 - 6.3e-10 39.3 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain zf-C2H2 PF00096.21 EIM84331.1 - 1.5e-09 37.6 10.6 2.3e-05 24.4 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM84331.1 - 2.2e-07 30.7 13.2 0.0076 16.5 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EIM84331.1 - 0.0018 18.4 7.3 0.14 12.3 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-met2 PF12907.2 EIM84331.1 - 0.0023 17.8 2.6 0.023 14.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-binding zf-Di19 PF05605.7 EIM84331.1 - 0.052 13.6 7.1 3.5 7.8 2.1 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EIM84331.1 - 0.25 11.7 20.1 0.31 11.3 0.1 4.4 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM84331.1 - 0.34 11.1 13.4 0.78 9.9 1.9 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIM84331.1 - 0.8 9.6 8.7 2.3 8.2 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIM84331.1 - 4.4 7.7 11.4 5 7.5 0.5 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain p450 PF00067.17 EIM84332.1 - 2.7e-68 230.5 0.0 3.6e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 STE3 PF02076.10 EIM84333.1 - 1.4e-87 293.3 16.1 1.6e-87 293.1 11.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.7 EIM84333.1 - 0.57 9.5 4.8 0.19 11.1 0.3 2.0 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor STE3 PF02076.10 EIM84334.1 - 2e-25 89.4 8.4 2.3e-25 89.2 5.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mod_r PF07200.8 EIM84335.1 - 0.029 14.2 2.3 0.052 13.4 1.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Syntaxin-6_N PF09177.6 EIM84335.1 - 0.029 14.7 3.0 0.091 13.1 2.1 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Spc7 PF08317.6 EIM84335.1 - 0.046 12.3 0.5 0.066 11.8 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3209 PF11483.3 EIM84335.1 - 0.061 13.6 2.6 0.16 12.3 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) FliE PF02049.13 EIM84335.1 - 0.13 12.3 0.2 0.64 10.0 0.0 2.1 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE COG2 PF06148.6 EIM84335.1 - 0.23 11.3 4.0 0.42 10.4 2.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.1 EIM84335.1 - 0.46 10.5 2.4 0.92 9.5 1.6 1.4 1 0 0 1 1 1 0 Syntaxin-like protein Med9 PF07544.8 EIM84335.1 - 0.67 9.7 3.2 1.4 8.7 0.6 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 p450 PF00067.17 EIM84336.1 - 7.4e-06 24.7 0.0 8.5e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84337.1 - 2.3e-55 187.9 0.0 2.7e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84338.1 - 5.9e-63 212.9 0.0 7.4e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EIM84339.1 - 6.4e-87 291.9 27.4 7.3e-87 291.8 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84339.1 - 6.7e-20 71.0 68.6 6.1e-19 67.9 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EIM84340.1 - 5.5e-10 38.8 0.2 2.1e-09 36.9 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM84340.1 - 1.8 8.3 4.9 32 4.2 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) EBP PF05241.7 EIM84342.1 - 2.3e-09 36.5 10.1 2.8e-09 36.2 7.0 1.1 1 0 0 1 1 1 1 Emopamil binding protein Cut8_N PF14482.1 EIM84343.1 - 0.83 9.6 7.1 1.2 9.2 2.4 2.6 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Phosphorylase PF00343.15 EIM84344.1 - 3.2e-296 983.9 0.0 3.7e-296 983.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase F-box-like PF12937.2 EIM84345.1 - 3.7e-08 32.9 0.0 1.2e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM84345.1 - 0.13 12.0 0.2 53 3.6 0.0 4.0 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EIM84345.1 - 0.48 10.0 2.9 8.4 6.1 0.0 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_hydro_28 PF00295.12 EIM84346.1 - 1.3e-55 188.6 14.5 1.6e-55 188.3 10.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM84346.1 - 7.5e-06 25.7 36.6 0.027 14.2 25.4 3.1 1 1 0 1 1 1 1 Right handed beta helix region HeLo PF14479.1 EIM84347.1 - 0.0068 16.1 0.8 0.024 14.4 0.6 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation BAG PF02179.11 EIM84348.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 2.7 3 0 0 3 3 3 1 BAG domain AAA_16 PF13191.1 EIM84352.1 - 0.0019 18.2 0.0 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RHSP PF07999.6 EIM84352.1 - 0.0059 15.2 0.1 1.7 7.1 0.1 2.4 1 1 0 2 2 2 2 Retrotransposon hot spot protein AAA_19 PF13245.1 EIM84352.1 - 0.019 14.6 0.0 0.098 12.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EIM84352.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.6 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIM84352.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UBN2_3 PF14244.1 EIM84353.1 - 0.0003 20.3 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type EcoRII-C PF09019.6 EIM84353.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 EcoRII C terminal Herpes_gE PF02480.11 EIM84354.1 - 5.1e-05 21.7 0.0 8.6e-05 20.9 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 EIM84354.1 - 0.0045 17.3 2.8 0.012 15.9 1.9 1.7 1 0 0 1 1 1 1 Alphavirus glycoprotein J PBP1_TM PF14812.1 EIM84354.1 - 9 6.6 7.7 1.1 9.5 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EAP30 PF04157.11 EIM84355.1 - 7.5e-30 103.7 0.0 4.4e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EIM84355.1 - 6.2e-22 77.2 0.0 1.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EIM84355.1 - 9.5e-05 21.4 11.1 0.0061 15.6 0.7 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EIM84355.1 - 0.0039 16.9 3.8 0.028 14.2 0.1 2.4 2 0 0 2 2 2 1 Double zinc ribbon GRAM PF02893.15 EIM84355.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-Sec23_Sec24 PF04810.10 EIM84355.1 - 0.055 13.0 5.5 0.32 10.5 0.1 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 EIM84355.1 - 1 8.6 7.8 0.16 11.2 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OTT_1508_deam PF14441.1 EIM84356.1 - 6.2e-08 32.5 0.1 2.4e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase STE PF02200.11 EIM84357.1 - 5.7e-58 193.8 0.1 8.6e-58 193.2 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EIM84357.1 - 4.7e-10 39.2 18.7 9.3e-06 25.6 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM84357.1 - 2.5e-08 33.7 15.4 0.00033 20.7 3.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM84357.1 - 1.1e-06 28.6 7.9 1.1e-06 28.6 5.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM84357.1 - 0.013 15.4 0.9 0.013 15.4 0.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIM84357.1 - 0.21 11.8 6.2 4.2 7.6 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIM84357.1 - 3.7 7.4 9.2 0.27 11.0 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-MYND PF01753.13 EIM84361.1 - 9.5e-08 31.7 16.5 1.8e-07 30.9 11.4 1.4 1 0 0 1 1 1 1 MYND finger DUF3844 PF12955.2 EIM84361.1 - 0.53 10.4 5.6 1.2 9.3 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) BAG PF02179.11 EIM84362.1 - 2.4e-05 24.3 1.8 3.7e-05 23.7 0.7 1.7 1 1 0 1 1 1 1 BAG domain FbpA PF05833.6 EIM84362.1 - 0.01 14.3 0.2 0.017 13.7 0.2 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2360 PF10152.4 EIM84364.1 - 1.7 8.9 5.4 3.7 7.8 3.7 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1687 PF07955.6 EIM84366.1 - 1.7e-08 34.5 1.7 7.2e-08 32.4 1.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 EIM84367.1 - 3.1e-07 29.8 0.0 9.5e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84367.1 - 0.067 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Zip PF02535.17 EIM84367.1 - 0.69 8.8 9.3 1.1 8.1 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Collagen PF01391.13 EIM84369.1 - 0.018 14.5 7.7 0.032 13.7 5.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Glyco_hydro_30 PF02055.11 EIM84370.1 - 2.4e-23 82.1 1.7 3.6e-23 81.5 1.2 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EIM84370.1 - 0.0041 16.0 0.0 0.022 13.7 0.0 1.9 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 IBR PF01485.16 EIM84375.1 - 7.3e-16 57.7 36.7 2.8e-08 33.5 5.1 3.8 4 0 0 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EIM84375.1 - 0.014 15.2 1.6 0.014 15.2 1.1 4.0 2 2 1 3 3 3 0 Ring finger domain ATE_N PF04376.8 EIM84375.1 - 0.11 12.2 4.3 0.35 10.6 2.9 1.8 1 1 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus DUF4604 PF15377.1 EIM84375.1 - 3.1 8.0 9.6 1.1 9.4 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) CsbD PF05532.7 EIM84378.1 - 0.31 10.7 4.0 0.64 9.7 2.7 1.4 1 0 0 1 1 1 0 CsbD-like Histone PF00125.19 EIM84379.1 - 1.3e-22 79.6 0.1 1.6e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM84379.1 - 0.0037 17.2 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ASF1_hist_chap PF04729.8 EIM84380.1 - 1e-57 194.0 0.0 1.3e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.14 EIM84381.1 - 2.2e-29 102.5 0.0 6.8e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIM84381.1 - 1.1e-11 44.7 0.3 3.5e-11 43.1 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Glyco_hydro_30 PF02055.11 EIM84383.1 - 1.1e-27 96.4 0.7 1.6e-27 95.9 0.5 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Adaptin_N PF01602.15 EIM84384.1 - 2.1e-152 508.1 4.8 2.7e-152 507.7 3.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIM84384.1 - 7.2e-28 97.6 1.1 3.3e-24 85.6 0.1 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIM84384.1 - 4.1e-18 65.4 1.1 3.1e-06 27.3 0.0 5.5 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EIM84384.1 - 3.3e-10 39.1 4.5 0.00024 20.9 0.1 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EIM84384.1 - 4e-07 30.3 5.6 0.0063 16.9 0.0 5.9 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EIM84384.1 - 0.0042 16.4 0.2 0.37 10.1 0.0 3.0 3 1 0 3 3 3 1 CLASP N terminal Arm PF00514.18 EIM84384.1 - 0.01 15.6 5.4 7 6.6 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1548 PF07579.6 EIM84384.1 - 0.012 15.6 0.2 4.6 7.3 0.0 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1548) UCH PF00443.24 EIM84385.1 - 7.9e-46 156.3 0.0 9.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM84385.1 - 1.6e-12 47.4 0.0 8.5e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EIM84385.1 - 3.4e-05 23.1 0.0 7.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.7 EIM84386.1 - 4.2e-54 182.9 3.9 5e-54 182.6 2.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Lge1 PF11488.3 EIM84386.1 - 0.078 13.1 1.7 0.14 12.3 1.2 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 TarH PF02203.10 EIM84386.1 - 0.27 11.0 3.6 0.56 10.0 2.5 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue Peptidase_C14 PF00656.17 EIM84387.1 - 1.3e-25 90.5 0.0 1.5e-16 60.8 0.0 2.6 2 1 0 2 2 2 2 Caspase domain CHAT PF12770.2 EIM84387.1 - 0.053 12.6 0.0 9.8 5.2 0.0 2.6 2 0 0 2 2 2 0 CHAT domain Peptidase_C14 PF00656.17 EIM84388.1 - 9.6e-17 61.4 0.1 1.2e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM84388.1 - 0.0088 15.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain RNase_H PF00075.19 EIM84389.1 - 0.00028 21.2 0.1 0.00048 20.4 0.0 1.4 2 0 0 2 2 2 1 RNase H Peptidase_C14 PF00656.17 EIM84390.1 - 6.4e-20 71.8 0.0 3.2e-15 56.5 0.0 2.0 1 1 1 2 2 2 2 Caspase domain DUF218 PF02698.12 EIM84390.1 - 0.0075 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Raptor_N PF14538.1 EIM84390.1 - 0.15 11.9 0.0 5.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Reo_sigmaC PF04582.7 EIM84391.1 - 0.0019 17.4 9.7 0.055 12.6 0.6 3.5 2 1 1 3 3 3 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EIM84391.1 - 0.45 10.6 39.3 0.026 14.6 8.8 3.8 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EIM84391.1 - 1.9 8.0 95.4 4.7 6.7 10.5 5.3 2 1 3 5 5 5 0 IncA protein RINGv PF12906.2 EIM84392.1 - 4.4e-06 26.6 5.0 8.4e-06 25.7 3.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 EIM84392.1 - 0.0013 18.8 2.2 0.0022 18.0 1.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIM84392.1 - 0.0019 18.0 4.6 0.0034 17.1 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zinc_ribbon_2 PF13240.1 EIM84392.1 - 0.036 13.5 0.7 0.074 12.5 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EIM84392.1 - 0.074 12.7 1.8 0.14 11.8 1.2 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIM84392.1 - 0.14 12.1 2.6 0.27 11.2 1.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_5 PF13719.1 EIM84392.1 - 0.14 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ogr_Delta PF04606.7 EIM84392.1 - 0.27 10.9 2.9 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C3HC4_2 PF13923.1 EIM84392.1 - 0.45 10.5 3.7 1.7 8.7 2.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 EIM84392.1 - 2.3 6.8 3.4 3.2 6.3 2.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor GTP_EFTU PF00009.22 EIM84393.1 - 1.2e-37 129.1 0.1 2.1e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EIM84393.1 - 9e-36 121.8 0.5 2.1e-35 120.6 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EIM84393.1 - 1.5e-10 41.0 0.5 1.5e-10 41.0 0.3 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM84393.1 - 0.026 14.4 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PNK3P PF08645.6 EIM84393.1 - 0.14 11.6 0.0 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase ICMT PF04140.9 EIM84396.1 - 3.6e-15 55.9 1.0 2.7e-13 49.9 0.7 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM84396.1 - 3.8e-13 49.4 2.5 1.3e-11 44.4 0.2 2.1 1 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM84396.1 - 4e-08 32.2 0.5 4.8e-08 31.9 0.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3112 PF11309.3 EIM84396.1 - 0.013 15.3 0.2 0.02 14.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Ni_hydr_CYTB PF01292.15 EIM84396.1 - 0.018 14.4 0.3 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1295 PF06966.7 EIM84396.1 - 0.054 12.7 0.7 0.13 11.5 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) 2TM PF13239.1 EIM84396.1 - 0.065 13.2 0.7 0.14 12.2 0.5 1.6 1 1 0 1 1 1 0 2TM domain UNC-93 PF05978.11 EIM84396.1 - 0.37 10.2 2.5 0.35 10.3 0.2 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 RRM_1 PF00076.17 EIM84397.1 - 8.2e-14 50.9 0.0 1.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM84397.1 - 1e-10 41.4 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM84397.1 - 3.8e-08 33.0 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM84397.1 - 0.0089 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PPR_3 PF13812.1 EIM84398.1 - 9.1e-05 22.4 0.0 0.91 9.9 0.0 4.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EIM84398.1 - 0.0026 17.6 0.0 2 8.5 0.0 3.0 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 EIM84398.1 - 0.0028 17.5 0.0 24 5.0 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family IATP PF04568.7 EIM84399.1 - 4.1e-12 45.9 5.0 4.5e-12 45.8 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Seryl_tRNA_N PF02403.17 EIM84399.1 - 0.3 11.1 6.7 0.35 10.8 4.7 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 EIM84399.1 - 5.1 6.5 5.8 5.3 6.4 4.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ATP_sub_h PF10775.4 EIM84400.1 - 2.6e-24 84.7 0.4 3.6e-24 84.2 0.3 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EIM84400.1 - 0.059 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 RNA_pol PF00940.14 EIM84401.1 - 8.1e-160 531.7 0.0 1.1e-159 531.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EIM84401.1 - 1.9e-73 247.4 0.0 3e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_3 PF13812.1 EIM84401.1 - 0.0034 17.5 0.0 0.043 14.1 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain GMC_oxred_N PF00732.14 EIM84403.1 - 8.7e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84403.1 - 3.1e-30 105.3 0.0 4.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM84403.1 - 0.0096 14.8 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM84403.1 - 0.015 15.2 0.2 0.047 13.7 0.1 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM84403.1 - 0.065 12.0 1.6 3.8 6.2 0.9 2.8 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EIM84403.1 - 0.1 12.4 0.1 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3827 PF12877.2 EIM84404.1 - 0.17 9.9 0.7 1 7.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) PPR_3 PF13812.1 EIM84405.1 - 7.3e-10 38.3 2.6 0.1 12.9 0.0 6.0 5 0 0 5 5 5 3 Pentatricopeptide repeat domain DUF605 PF04652.11 EIM84405.1 - 0.00029 20.3 28.1 0.00029 20.3 19.5 2.0 2 0 0 2 2 2 1 Vta1 like PPR PF01535.15 EIM84405.1 - 0.0032 17.3 0.4 14 5.9 0.0 5.3 5 1 0 5 5 5 1 PPR repeat SOG2 PF10428.4 EIM84405.1 - 2.1 6.9 40.9 0.16 10.5 23.4 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein TFIIA PF03153.8 EIM84405.1 - 3.4 7.4 25.0 0.34 10.7 13.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EIM84405.1 - 7.2 4.7 39.7 12 4.0 27.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Ldh_1_N PF00056.18 EIM84406.1 - 3.2e-40 137.1 0.1 4.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIM84406.1 - 1.7e-37 128.7 0.0 2.3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIM84406.1 - 0.006 15.3 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EIM84406.1 - 0.17 10.9 2.0 2.8 6.9 0.1 3.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAM_LAG1_CLN8 PF03798.11 EIM84407.1 - 0.033 13.7 5.8 0.072 12.6 4.0 1.6 1 0 0 1 1 1 0 TLC domain FTCD_N PF07837.7 EIM84408.1 - 0.031 13.7 0.0 0.097 12.1 0.0 1.8 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain AA_permease_2 PF13520.1 EIM84410.1 - 1e-56 192.3 44.5 1.2e-56 192.0 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM84410.1 - 5e-16 58.1 35.5 8e-16 57.4 24.6 1.3 1 0 0 1 1 1 1 Amino acid permease Phage_holin_5 PF06946.6 EIM84410.1 - 0.0035 17.4 2.0 0.0071 16.4 0.4 2.3 2 0 0 2 2 2 1 Phage holin F-box-like PF12937.2 EIM84412.1 - 4.2e-06 26.3 0.2 1.2e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM84412.1 - 0.039 13.7 0.8 7.9 6.3 0.1 3.3 2 0 0 2 2 2 0 Leucine rich repeat F-box PF00646.28 EIM84412.1 - 1.3 8.7 7.4 7.9 6.2 0.0 3.9 3 0 0 3 3 3 0 F-box domain DUF1365 PF07103.6 EIM84413.1 - 1.1e-27 96.7 0.0 8.1e-27 93.8 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Securin PF04856.8 EIM84414.1 - 0.025 14.2 7.1 0.033 13.9 5.0 1.1 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor CDC45 PF02724.9 EIM84414.1 - 0.61 8.0 5.2 0.8 7.6 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mitoc_L55 PF09776.4 EIM84414.1 - 0.64 9.6 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 DUF4407 PF14362.1 EIM84414.1 - 1.4 7.8 7.3 1.5 7.6 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.3 EIM84414.1 - 4.5 6.4 16.2 7.7 5.6 11.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aminotran_3 PF00202.16 EIM84416.1 - 8.6e-47 159.6 0.0 1.7e-46 158.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III GMC_oxred_N PF00732.14 EIM84419.1 - 9.4e-45 153.0 0.0 2.5e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84419.1 - 2.1e-31 109.1 0.0 3.9e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM84419.1 - 0.043 12.7 0.4 0.45 9.3 0.1 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase BP28CT PF08146.7 EIM84420.1 - 2.2e-29 102.1 0.0 1.1e-26 93.3 0.0 3.3 2 0 0 2 2 2 2 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EIM84420.1 - 2.1e-09 37.3 9.1 5.9e-09 35.9 4.7 3.2 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EIM84420.1 - 0.00025 21.2 11.0 0.59 10.4 0.1 5.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EIM84420.1 - 0.0004 20.2 3.8 0.043 13.9 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EIM84420.1 - 0.0043 17.4 0.3 16 5.9 0.0 4.2 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIM84420.1 - 0.05 14.0 9.2 0.37 11.3 0.4 5.5 3 1 3 6 6 6 0 HEAT-like repeat ParcG PF10274.4 EIM84420.1 - 0.13 12.1 0.2 41 4.0 0.2 3.5 2 1 1 3 3 3 0 Parkin co-regulated protein RNA_pol_I_A49 PF06870.7 EIM84421.1 - 1.6e-75 254.0 0.0 2e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TraC_F_IV PF11130.3 EIM84421.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Retrotrans_gag PF03732.12 EIM84422.1 - 5.2e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM84422.1 - 0.016 15.1 1.3 0.028 14.3 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2063 PF09836.4 EIM84423.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) DUF3816 PF12822.2 EIM84424.1 - 6.7 6.5 20.1 1.3 8.8 7.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3816) Transpos_assoc PF13963.1 EIM84427.1 - 0.00045 20.1 0.7 0.3 11.1 0.1 2.2 2 0 0 2 2 2 2 Transposase-associated domain Glyco_transf_17 PF04724.8 EIM84428.1 - 3.6e-100 335.4 0.0 4e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 F-box-like PF12937.2 EIM84429.1 - 1.2e-05 24.9 0.0 4.6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 F-box-like Sensor PF13796.1 EIM84433.1 - 0.00078 19.1 1.2 0.00094 18.8 0.8 1.1 1 0 0 1 1 1 1 Putative sensor BatA PF07584.6 EIM84433.1 - 0.002 18.2 0.2 0.003 17.7 0.1 1.2 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal RCR PF12273.3 EIM84433.1 - 0.0062 17.0 8.5 0.013 16.0 5.9 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EIM84433.1 - 0.0096 16.1 0.2 0.022 14.9 0.1 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EIM84433.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.1 EIM84433.1 - 0.013 14.0 0.0 0.015 13.8 0.0 1.0 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.5 EIM84433.1 - 0.023 14.0 8.0 0.038 13.3 5.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EVC2_like PF12297.3 EIM84433.1 - 0.063 11.8 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein IncA PF04156.9 EIM84433.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF4381 PF14316.1 EIM84433.1 - 0.1 12.7 0.1 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM154 PF15102.1 EIM84433.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1191 PF06697.7 EIM84433.1 - 0.14 10.9 1.8 0.12 11.1 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EIM84433.1 - 0.6 8.3 3.9 1.9 6.6 2.7 1.8 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EIM84433.1 - 1.6 8.2 4.3 1.3 8.6 2.1 1.4 2 0 0 2 2 2 0 Rifin/stevor family Mid2 PF04478.7 EIM84433.1 - 3 7.2 5.1 0.84 9.0 1.6 1.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor PMI_typeI PF01238.16 EIM84434.1 - 7.5e-67 225.8 0.0 7.5e-66 222.6 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIM84434.1 - 0.00017 21.0 0.6 0.24 10.9 0.3 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EIM84434.1 - 0.011 15.4 0.0 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_3 PF05899.7 EIM84434.1 - 0.022 14.1 0.3 0.09 12.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EIM84434.1 - 0.11 12.0 0.0 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Cupin SSF PF00474.12 EIM84437.1 - 1.1e-17 63.7 28.1 2.3e-17 62.7 19.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Aldo_ket_red PF00248.16 EIM84438.1 - 1e-72 244.3 0.1 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIM84438.1 - 0.012 15.4 0.1 7.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family SRP9-21 PF05486.7 EIM84440.1 - 1.8e-17 62.7 0.3 2.3e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) STE3 PF02076.10 EIM84442.1 - 4.5e-68 229.3 8.1 5.2e-68 229.1 5.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor adh_short PF00106.20 EIM84445.1 - 9.3e-18 64.6 0.7 1.9e-17 63.6 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84445.1 - 9.8e-14 51.6 0.5 4.3e-13 49.5 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM84445.1 - 1.1e-08 34.9 0.2 5.2e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM84445.1 - 5.6e-06 26.4 0.1 1.8e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIM84445.1 - 0.00015 21.3 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84445.1 - 0.0046 16.2 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EIM84445.1 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIM84445.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_18 PF00704.23 EIM84446.1 - 1.7e-06 27.7 2.0 2.2e-06 27.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.22 EIM84448.1 - 3.5e-60 199.7 4.3 3.2e-21 74.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PigN PF04987.9 EIM84449.1 - 6e-107 358.0 0.7 8.3e-107 357.5 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EIM84449.1 - 0.00056 19.3 0.0 2.3 7.4 0.0 3.0 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIM84449.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Sulfatase RRM_6 PF14259.1 EIM84450.1 - 0.00016 21.5 0.0 4.5 7.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM84450.1 - 0.0014 18.2 0.0 1.1 8.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM84450.1 - 0.0039 17.0 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM84451.1 - 9e-12 44.8 0.0 0.045 13.7 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM84451.1 - 1.3e-11 43.9 0.0 0.021 14.4 0.0 5.1 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM84451.1 - 1.2e-05 25.0 0.2 1.2 9.0 0.0 5.4 6 1 0 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRCC PF10253.4 EIM84454.1 - 3.2 8.4 9.2 0.35 11.5 2.0 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Lin-8 PF03353.10 EIM84454.1 - 4.1 6.6 5.0 6.7 5.8 3.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ORC6 PF05460.8 EIM84454.1 - 4.3 6.3 8.9 7.6 5.5 6.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) OTU PF02338.14 EIM84455.1 - 3.9e-17 62.9 0.0 8.3e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIM84455.1 - 0.16 11.2 0.1 2.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Cytomega_US3 PF05963.6 EIM84457.1 - 0.088 12.1 1.3 0.14 11.5 0.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus US3 protein DUF912 PF06024.7 EIM84457.1 - 1.3 9.1 4.1 0.27 11.3 0.3 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SET PF00856.23 EIM84458.1 - 5e-21 75.6 0.6 5e-21 75.6 0.4 3.9 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EIM84458.1 - 9.5e-16 57.5 8.4 9.5e-16 57.5 5.8 1.9 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain PCYCGC PF13798.1 EIM84458.1 - 7.8 6.1 10.8 5.9 6.5 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function with PCYCGC motif PP28 PF10252.4 EIM84459.1 - 4e-25 87.6 13.8 4e-25 87.6 9.5 2.5 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Complex1_LYR PF05347.10 EIM84460.1 - 3.2e-09 36.4 0.0 6.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIM84460.1 - 1.5e-06 28.2 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIM84460.1 - 0.0034 17.8 0.0 0.0042 17.5 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Homez PF11569.3 EIM84460.1 - 0.052 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Bac_rhamnosid PF05592.6 EIM84461.1 - 2.9e-27 95.0 0.1 3.8e-26 91.3 0.2 2.3 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EIM84461.1 - 0.00019 20.2 0.1 0.00028 19.6 0.1 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EIM84461.1 - 0.033 12.8 0.1 0.13 10.9 0.1 1.8 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Glyco_hydro_61 PF03443.9 EIM84462.1 - 1.4e-45 155.7 0.0 1.7e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kelch_4 PF13418.1 EIM84463.1 - 4.3e-39 132.0 28.2 3e-09 36.5 0.1 7.3 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EIM84463.1 - 2.8e-34 116.4 33.0 1.1e-07 31.8 0.0 8.6 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EIM84463.1 - 1e-31 108.1 6.8 2.9e-07 29.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EIM84463.1 - 1.2e-31 108.0 10.8 3.3e-07 30.0 0.1 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EIM84463.1 - 1.9e-24 84.7 13.0 7e-05 22.8 0.0 6.7 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EIM84463.1 - 9.6e-12 44.1 22.6 8.7e-05 22.1 0.1 7.0 7 0 0 7 7 7 4 Kelch motif SUI1 PF01253.17 EIM84466.1 - 1.1e-13 50.7 0.5 1.9e-13 49.9 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 UbiA PF01040.13 EIM84467.1 - 3.4e-19 69.0 6.7 3.4e-19 69.0 4.7 1.4 1 1 1 2 2 2 1 UbiA prenyltransferase family Euplotes_phero PF05842.6 EIM84469.1 - 0.032 14.5 2.0 0.032 14.5 1.4 2.2 1 1 1 2 2 2 0 Euplotes octocarinatus mating pheromone protein DUF716 PF04819.7 EIM84470.1 - 0.00077 18.9 4.2 0.0014 18.0 2.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF716) Sugar_tr PF00083.19 EIM84473.1 - 2.9e-102 342.5 26.1 3.4e-102 342.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84473.1 - 6.3e-28 97.4 54.0 1.5e-25 89.6 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rtt106 PF08512.7 EIM84474.1 - 3.1e-07 30.2 0.0 0.0051 16.7 0.0 2.3 2 0 0 2 2 2 2 Histone chaperone Rttp106-like RrnaAD PF00398.15 EIM84475.1 - 4.5e-56 189.7 0.0 6e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIM84475.1 - 7.9e-10 38.7 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM84475.1 - 8e-06 26.4 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM84475.1 - 1.2e-05 24.7 0.0 2.8e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EIM84475.1 - 9.1e-05 21.7 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EIM84475.1 - 0.00066 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EIM84475.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM84475.1 - 0.0016 18.0 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIM84475.1 - 0.0024 16.9 0.0 0.0052 15.9 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EIM84475.1 - 0.0057 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EIM84475.1 - 0.036 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Baculo_PEP_C PF04513.7 EIM84476.1 - 0.012 15.4 7.5 0.022 14.6 0.0 3.6 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SseC PF04888.7 EIM84476.1 - 3.4 6.9 11.6 6 6.1 8.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF566 PF04484.7 EIM84478.1 - 2.6 7.4 23.3 4.1 6.8 16.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) SOBP PF15279.1 EIM84478.1 - 6.6 7.0 10.3 9.4 6.5 7.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein MFS_1 PF07690.11 EIM84480.1 - 8.3e-39 133.2 45.9 1e-28 100.0 11.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIM84480.1 - 6.8e-05 21.1 3.5 0.00039 18.6 0.8 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EIM84480.1 - 0.013 15.2 3.4 0.021 14.6 0.1 2.7 2 0 0 2 2 2 0 MFS_1 like family UNC-93 PF05978.11 EIM84480.1 - 0.46 9.9 10.1 0.081 12.4 1.9 2.6 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 zf-CCCH PF00642.19 EIM84481.1 - 1e-06 28.2 3.1 2e-06 27.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIM84481.1 - 0.0027 17.6 0.4 0.0054 16.6 0.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type BAG PF02179.11 EIM84482.1 - 9.8e-06 25.5 1.3 1.7e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 BAG domain IQ PF00612.22 EIM84482.1 - 0.0076 15.8 1.7 0.033 13.8 1.2 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif F-box-like PF12937.2 EIM84483.1 - 6.6e-05 22.5 0.6 0.00022 20.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM84483.1 - 0.092 12.4 1.1 26 4.5 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Ctr PF04145.10 EIM84484.1 - 1.5e-25 89.9 0.1 2.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family MRC1 PF09444.5 EIM84485.1 - 0.93 9.8 7.3 1.3 9.3 5.1 1.2 1 0 0 1 1 1 0 MRC1-like domain Ferric_reduct PF01794.14 EIM84486.1 - 2e-15 56.9 7.1 2e-15 56.9 4.9 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EIM84486.1 - 1.2e-09 38.2 0.0 2.8e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM84486.1 - 6.5e-08 32.4 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF3089 PF11288.3 EIM84487.1 - 0.04 13.0 0.2 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) tRNA_synt_1c_R1 PF04558.10 EIM84487.1 - 0.077 12.5 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Aldo_ket_red PF00248.16 EIM84488.1 - 6.6e-39 133.4 0.0 7.5e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3808 PF10300.4 EIM84491.1 - 7.1e-79 265.5 0.0 2.5e-41 141.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EIM84491.1 - 0.015 14.9 1.9 0.22 11.1 0.2 3.0 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 EIM84491.1 - 0.019 14.8 4.5 1.7 8.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84491.1 - 0.19 11.5 1.6 23 5.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM84491.1 - 1.3 9.0 7.2 5.7 6.9 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat APH PF01636.18 EIM84492.1 - 6.8e-19 68.5 0.1 9.4e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM84492.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EIM84492.1 - 0.019 13.6 0.0 0.04 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EIM84492.1 - 0.024 13.7 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EIM84492.1 - 0.024 13.9 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 EIM84493.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM84493.1 - 0.0002 20.9 0.0 0.00028 20.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase STE3 PF02076.10 EIM84494.1 - 2.1e-87 292.7 19.4 2.5e-87 292.5 13.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor zf-MYND PF01753.13 EIM84495.1 - 2.5e-10 40.0 9.0 2.5e-10 40.0 6.2 2.4 2 0 0 2 2 2 1 MYND finger zf-H2C2_2 PF13465.1 EIM84495.1 - 0.2 11.9 2.4 0.75 10.1 1.6 2.0 1 0 0 1 1 1 0 Zinc-finger double domain RNase_T PF00929.19 EIM84496.1 - 3.6e-21 76.1 0.0 5.6e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Herpes_UL47 PF03362.8 EIM84497.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein F-box-like PF12937.2 EIM84500.1 - 2.2e-06 27.2 0.1 6.3e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM84501.1 - 2.8e-08 33.3 0.6 2.8e-08 33.3 0.5 2.8 4 0 0 4 4 4 1 F-box-like Suf PF05843.9 EIM84501.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Aldedh PF00171.17 EIM84503.1 - 2.9e-80 269.8 0.0 3.6e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 EIM84503.1 - 0.0084 16.7 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family RHH_3 PF12651.2 EIM84503.1 - 0.049 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain Glyco_hydro_38 PF01074.17 EIM84504.1 - 1.4e-82 277.0 0.1 2.5e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EIM84504.1 - 1e-60 205.8 0.0 1.4e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EIM84504.1 - 4.6e-25 87.6 0.0 1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Ferritin_2 PF13668.1 EIM84505.1 - 1.4e-39 135.1 2.5 2.2e-39 134.5 1.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain Pkinase_Tyr PF07714.12 EIM84507.1 - 0.0023 17.0 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_1 PF00667.15 EIM84508.1 - 1.4e-36 125.9 0.0 6e-36 123.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIM84508.1 - 7.5e-30 103.8 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIM84508.1 - 2.6e-12 47.2 0.0 5.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EIM84508.1 - 0.061 13.3 0.0 0.22 11.5 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain SNase PF00565.12 EIM84511.1 - 1.9e-18 66.6 0.3 3.7e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Yip1 PF04893.12 EIM84513.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain DUF1180 PF06679.7 EIM84513.1 - 6.9 6.5 8.1 7.8 6.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) SNF2_N PF00176.18 EIM84514.1 - 9.8e-71 237.9 0.9 1.3e-70 237.6 0.6 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM84514.1 - 1.6e-12 47.1 0.0 3.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM84514.1 - 2.9e-06 27.2 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EIM84514.1 - 9.8e-05 22.1 2.4 0.00021 21.0 1.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM84514.1 - 0.0022 17.6 3.0 0.0083 15.7 2.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM84514.1 - 0.003 17.5 4.7 0.011 15.7 3.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM84514.1 - 0.0056 16.3 0.1 0.0056 16.3 0.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIM84514.1 - 0.0078 15.9 4.7 0.026 14.2 3.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM84514.1 - 0.017 14.9 0.7 0.017 14.9 0.5 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 EIM84514.1 - 0.12 12.2 1.5 0.29 11.0 1.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EIM84514.1 - 1.4 8.8 3.5 2.5 8.0 0.6 2.4 2 1 0 2 2 2 0 IBR domain PALP PF00291.20 EIM84517.1 - 1.8e-68 231.0 0.2 2e-68 230.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 EIM84517.1 - 0.1 12.1 1.9 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein zf-MYND PF01753.13 EIM84518.1 - 1.6e-10 40.6 13.3 1.6e-10 40.6 9.2 2.4 3 0 0 3 3 3 1 MYND finger PolC_DP2 PF03833.8 EIM84518.1 - 2 5.9 6.8 3.1 5.3 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nop14 PF04147.7 EIM84519.1 - 0.042 11.7 13.5 0.055 11.3 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.4 EIM84519.1 - 0.14 10.3 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SDA1 PF05285.7 EIM84519.1 - 0.67 9.1 11.4 0.94 8.6 7.9 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 EIM84519.1 - 1.2 7.1 2.5 1.5 6.8 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.5 EIM84519.1 - 2.9 8.1 23.3 0.23 11.7 12.3 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.3 EIM84519.1 - 6 6.7 17.2 11 5.8 11.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Upf2 PF04050.9 EIM84519.1 - 7.1 6.3 12.6 13 5.4 8.7 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CDC45 PF02724.9 EIM84519.1 - 8.7 4.2 13.3 13 3.6 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 EIM84525.1 - 4.7e-10 38.9 0.9 2.7e-06 27.0 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Dynamin_M PF01031.15 EIM84526.1 - 0.00016 20.5 0.1 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EIM84526.1 - 0.0061 16.4 0.2 0.018 14.9 0.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain F-box-like PF12937.2 EIM84527.1 - 3.1e-05 23.5 1.3 0.00014 21.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like Melittin PF01372.12 EIM84527.1 - 0.019 14.3 0.4 0.041 13.2 0.3 1.5 1 0 0 1 1 1 0 Melittin DUF4404 PF14357.1 EIM84529.1 - 0.046 14.1 2.5 0.21 12.0 1.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) APG6 PF04111.7 EIM84529.1 - 0.095 11.7 0.9 0.14 11.1 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PEHE PF15275.1 EIM84532.1 - 0.038 14.4 1.5 0.085 13.3 1.1 1.6 1 0 0 1 1 1 0 PEHE domain DARPP-32 PF05395.7 EIM84532.1 - 0.39 10.8 3.5 0.54 10.3 2.4 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 F-box PF00646.28 EIM84535.1 - 0.05 13.2 0.6 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 F-box domain ABC_membrane PF00664.18 EIM84536.1 - 0.0062 15.9 1.2 0.012 15.0 0.8 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region HAD PF12710.2 EIM84536.1 - 0.028 14.5 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RE_EcoO109I PF14511.1 EIM84536.1 - 0.11 11.9 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I Transposase_21 PF02992.9 EIM84541.1 - 3.7e-11 42.5 0.0 4.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Adeno_PV PF03910.8 EIM84545.1 - 0.2 10.6 2.2 0.28 10.1 1.5 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV HLH PF00010.21 EIM84548.1 - 1.2e-10 40.8 0.0 3.1e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.14 EIM84548.1 - 1.3 8.9 9.1 0.55 10.0 3.9 2.4 2 0 0 2 2 2 0 AT hook motif F-box-like PF12937.2 EIM84551.1 - 5.2e-07 29.2 1.9 1.9e-06 27.4 1.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM84551.1 - 0.066 12.8 1.4 0.57 9.9 0.2 2.9 3 0 0 3 3 3 0 F-box domain DUF1956 PF09209.6 EIM84552.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) Peptidase_M24 PF00557.19 EIM84554.1 - 1e-05 25.2 0.1 1e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2638 PF10937.3 EIM84555.1 - 0.11 13.5 3.5 0.35 11.8 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) OB_NTP_bind PF07717.11 EIM84557.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold BLUF PF04940.7 EIM84557.1 - 0.058 13.1 0.1 0.33 10.6 0.1 2.0 1 1 1 2 2 2 0 Sensors of blue-light using FAD DUF3534 PF12053.3 EIM84557.1 - 0.058 13.2 0.7 0.14 12.0 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) GDH_N PF12466.3 EIM84557.1 - 0.94 9.5 6.2 0.15 12.1 0.9 2.2 3 0 0 3 3 3 0 Glutamate dehydrogenase N terminal Zn_clus PF00172.13 EIM84558.1 - 2.9e-10 39.8 22.6 5e-08 32.7 6.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 EIM84562.1 - 6.8e-08 32.2 10.9 2.3e-07 30.5 3.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM84562.1 - 1.2e-06 28.3 10.3 3e-06 27.1 4.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM84562.1 - 1.7e-06 27.6 9.9 6.5e-06 25.7 3.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM84562.1 - 9.9e-06 25.1 5.6 9.9e-06 25.1 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM84562.1 - 4.5e-05 23.0 4.9 6e-05 22.6 1.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIM84562.1 - 6.2e-05 22.7 8.4 0.0018 18.0 3.7 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIM84562.1 - 0.0036 16.9 13.0 0.038 13.6 6.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM84562.1 - 0.0083 16.2 4.9 0.015 15.3 2.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-4CXXC_R1 PF10497.4 EIM84562.1 - 0.029 14.4 1.8 6.4 6.9 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Baculo_RING PF05883.6 EIM84562.1 - 0.038 13.8 0.3 0.062 13.1 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EIM84562.1 - 0.13 11.8 8.4 6.8 6.3 4.0 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EIM84562.1 - 0.86 9.5 7.7 2.3 8.1 5.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger Tmpp129 PF10272.4 EIM84562.1 - 1 7.9 4.0 1.5 7.4 1.6 1.9 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-MIZ PF02891.15 EIM84562.1 - 1.2 8.6 11.5 16 5.0 6.3 2.9 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CHY PF05495.7 EIM84562.1 - 1.5 9.0 7.4 0.62 10.2 2.2 2.2 3 0 0 3 3 2 0 CHY zinc finger IBR PF01485.16 EIM84562.1 - 1.8 8.4 8.6 2.4 8.1 3.7 2.4 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 EIM84562.1 - 2 8.4 7.2 10 6.1 3.4 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain zf-Nse PF11789.3 EIM84562.1 - 2.5 7.6 6.2 0.2 11.2 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Transposase_21 PF02992.9 EIM84565.1 - 3.7e-09 36.0 0.0 6.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RNA_pol_Rpb2_7 PF04560.15 EIM84565.1 - 0.038 14.2 0.2 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 EPTP PF03736.12 EIM84566.1 - 0.14 11.8 0.1 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 EPTP domain Phyto_Pns9_10 PF05878.6 EIM84566.1 - 0.93 8.4 8.5 1.3 7.9 5.9 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 UPF0193 PF05250.6 EIM84566.1 - 5.8 6.4 15.2 3.9e+02 0.4 10.5 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0193) Flagellin_N PF00669.15 EIM84569.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region zf-H2C2_2 PF13465.1 EIM84570.1 - 0.00039 20.5 10.4 0.00073 19.7 2.8 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIM84570.1 - 0.00083 19.5 16.3 0.065 13.5 2.7 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIM84570.1 - 0.073 13.1 5.9 1.6 8.8 0.5 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIM84570.1 - 0.1 13.0 18.8 1 9.8 1.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 EIM84570.1 - 0.19 11.5 3.2 0.31 10.8 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger domain Cauli_VI PF01693.11 EIM84571.1 - 0.032 14.2 0.0 1.9 8.5 0.0 2.5 2 1 0 2 2 2 0 Caulimovirus viroplasmin Zn_clus PF00172.13 EIM84572.1 - 4.1e-10 39.3 8.6 4.1e-10 39.3 6.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIM PF04434.12 EIM84576.1 - 1e-06 28.0 0.5 2.7e-06 26.7 0.4 1.8 1 0 0 1 1 1 1 SWIM zinc finger DUF4218 PF13960.1 EIM84579.1 - 0.0054 16.1 0.2 0.01 15.2 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) RVT_1 PF00078.22 EIM84580.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF805 PF05656.9 EIM84580.1 - 0.074 12.8 0.3 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) EPSP_synthase PF00275.15 EIM84582.1 - 6.8e-84 281.7 0.3 1.1e-83 281.0 0.2 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EIM84582.1 - 7.2e-68 228.3 0.0 1.2e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DUF1708 PF08101.6 EIM84582.1 - 2.1e-12 46.6 0.0 3.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Fe-ADH_2 PF13685.1 EIM84582.1 - 0.0015 17.8 0.1 0.15 11.3 0.0 3.2 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase GMC_oxred_N PF00732.14 EIM84584.1 - 2.9e-57 194.1 0.0 3.7e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84584.1 - 7.4e-37 126.8 0.0 1.3e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM84584.1 - 0.00013 21.0 0.2 0.00044 19.2 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM84584.1 - 0.00033 20.6 0.0 0.016 15.2 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM84584.1 - 0.00039 19.3 0.2 0.0096 14.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EIM84584.1 - 0.0017 17.3 0.1 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM84584.1 - 0.092 11.2 0.2 1.9 6.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein UQ_con PF00179.21 EIM84586.1 - 2.3e-39 134.0 0.0 3.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pneumo_att_G PF05539.6 EIM84586.1 - 2.8 7.2 11.3 4.8 6.4 7.8 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ORC6 PF05460.8 EIM84586.1 - 4.8 6.1 7.9 6.3 5.7 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EIM84586.1 - 9.5 5.5 15.0 12 5.1 10.4 1.2 1 0 0 1 1 1 0 Vta1 like O-FucT PF10250.4 EIM84587.1 - 1.3e-06 27.8 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase 4HBT_2 PF13279.1 EIM84588.1 - 3.2e-08 34.0 0.0 5.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily COesterase PF00135.23 EIM84589.1 - 5.2e-103 345.5 0.0 6.5e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM84589.1 - 1e-07 31.7 0.3 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM84589.1 - 0.0014 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ABC1 PF03109.11 EIM84592.1 - 8.8e-26 90.2 0.0 1.8e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family GST_N_3 PF13417.1 EIM84594.1 - 6e-18 64.8 0.0 9.5e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM84594.1 - 1.8e-16 60.0 0.0 2.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM84594.1 - 5.2e-14 51.9 0.0 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM84594.1 - 1.3e-10 41.1 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM84594.1 - 2.4e-05 24.1 0.1 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM84594.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MtaB PF12176.3 EIM84594.1 - 0.023 13.1 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Glutaredoxin PF00462.19 EIM84594.1 - 0.047 13.6 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin MetRS-N PF09635.5 EIM84594.1 - 0.082 13.2 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 MetRS-N binding domain Saccharop_dh PF03435.13 EIM84595.1 - 7.2e-23 81.1 0.1 1.1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIM84595.1 - 2e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM84595.1 - 6.2e-05 22.5 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84595.1 - 0.00018 20.8 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EIM84595.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIM84595.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIM84595.1 - 0.0029 17.8 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EIM84595.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EIM84595.1 - 0.025 13.2 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2480 PF10652.4 EIM84595.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) EF-hand_9 PF14658.1 EIM84595.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Polysacc_lyase PF14099.1 EIM84598.1 - 0.012 15.2 1.7 0.048 13.3 1.2 1.9 1 1 0 1 1 1 0 Polysaccharide lyase Polysacc_lyase PF14099.1 EIM84599.1 - 0.06 12.9 0.7 0.24 11.0 0.5 1.8 1 1 0 1 1 1 0 Polysaccharide lyase TLD PF07534.11 EIM84600.1 - 6.2e-33 113.7 0.0 1.2e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 TLD Prismane PF03063.15 EIM84602.1 - 0.022 13.1 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Pkinase_Tyr PF07714.12 EIM84603.1 - 5.8e-51 173.0 0.0 1.4e-50 171.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM84603.1 - 8.1e-43 146.4 0.0 1.9e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIM84603.1 - 0.00029 19.9 0.4 0.00059 18.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM84603.1 - 0.0054 16.1 0.2 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Rad60-SLD PF11976.3 EIM84606.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Gti1_Pac2 PF09729.4 EIM84610.1 - 1.3e-27 96.6 0.2 3.1e-23 82.4 0.2 2.3 1 1 0 2 2 2 2 Gti1/Pac2 family HHH_8 PF14716.1 EIM84612.1 - 8.4e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Myc_N PF01056.13 EIM84612.1 - 0.35 9.9 11.8 0.016 14.4 3.3 2.0 2 0 0 2 2 2 0 Myc amino-terminal region Spt5_N PF11942.3 EIM84612.1 - 0.52 10.9 15.7 3.2 8.4 0.0 2.7 3 1 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EIM84612.1 - 0.61 10.4 17.1 0.79 10.0 4.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EIM84612.1 - 0.83 9.9 9.8 0.49 10.6 2.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.1 EIM84612.1 - 2.5 7.7 8.4 1.7 8.3 2.7 2.2 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 EIM84612.1 - 5.5 6.5 14.1 2.3 7.7 6.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF4588 PF15251.1 EIM84613.1 - 5.5e-05 23.2 0.1 5.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) LOH1CR12 PF10158.4 EIM84613.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein Methyltransf_22 PF13383.1 EIM84616.1 - 7.4e-28 97.7 0.0 1.6e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.7 EIM84616.1 - 8.5e-08 32.3 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain Transpos_assoc PF13963.1 EIM84617.1 - 0.06 13.3 2.7 3.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Transposase-associated domain zf-C2H2_4 PF13894.1 EIM84617.1 - 0.34 11.3 9.8 0.7 10.3 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIM84618.1 - 0.016 15.4 18.9 0.23 11.8 0.0 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger gpUL132 PF11359.3 EIM84619.1 - 0.0041 16.4 3.6 0.0075 15.6 2.5 1.4 1 0 0 1 1 1 1 Glycoprotein UL132 TMEM154 PF15102.1 EIM84619.1 - 0.0066 16.1 0.3 0.012 15.3 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EIM84619.1 - 0.013 15.1 0.2 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family EVC2_like PF12297.3 EIM84619.1 - 0.04 12.5 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Adeno_E3_CR2 PF02439.10 EIM84619.1 - 0.16 11.5 1.2 0.35 10.4 0.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ApoO PF09769.4 EIM84620.1 - 3e-28 98.5 0.0 8.6e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O DUF883 PF05957.8 EIM84620.1 - 0.3 11.5 8.8 1.2 9.5 0.5 3.9 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Spectrin PF00435.16 EIM84620.1 - 4.5 7.6 5.7 29 5.0 0.3 2.9 3 0 0 3 3 3 0 Spectrin repeat Ribosomal_L31 PF01197.13 EIM84621.1 - 0.084 12.8 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L31 Gp_dh_C PF02800.15 EIM84622.1 - 0.063 12.7 0.3 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TMEM154 PF15102.1 EIM84623.1 - 0.0038 16.9 0.3 0.0094 15.6 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.1 EIM84623.1 - 0.044 13.9 0.3 0.12 12.5 0.2 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator HPIH PF13323.1 EIM84624.1 - 0.03 14.0 0.1 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif zf-C2H2_4 PF13894.1 EIM84624.1 - 0.051 13.9 5.0 3.3 8.2 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger ERO1 PF04137.10 EIM84626.1 - 0.049 12.6 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TRAP_alpha PF03896.11 EIM84627.1 - 0.17 10.8 2.3 0.18 10.7 0.1 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AAA PF00004.24 EIM84628.1 - 7.2e-15 55.3 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM84628.1 - 0.0013 18.8 1.0 0.012 15.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM84628.1 - 0.0052 16.5 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIM84628.1 - 0.006 15.6 0.0 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EIM84628.1 - 0.045 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EIM84628.1 - 0.086 12.6 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EIM84628.1 - 0.15 11.9 1.1 1.7 8.5 0.2 2.4 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EIM84628.1 - 0.17 11.0 1.4 0.3 10.1 0.3 1.9 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 EIM84629.1 - 1.4e-07 31.3 0.0 3.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIM84629.1 - 0.00017 21.6 0.0 0.00071 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM84629.1 - 0.00074 19.5 0.0 0.0043 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EIM84629.1 - 0.0031 16.4 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EIM84629.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GMC_oxred_N PF00732.14 EIM84630.1 - 6.4e-64 215.9 0.0 8.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84630.1 - 5.3e-32 111.1 0.0 9.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM84630.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM84630.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.22 EIM84632.1 - 7.6e-48 162.2 0.0 1.2e-27 96.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM84632.1 - 9.3e-47 159.7 22.5 9.9e-21 74.3 2.3 3.5 3 1 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EIM84632.1 - 6.1e-10 39.5 0.0 0.39 10.6 0.0 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EIM84632.1 - 1.5e-07 30.8 0.0 0.029 13.6 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM84632.1 - 7.7e-07 28.7 0.0 0.0051 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIM84632.1 - 4e-06 25.9 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EIM84632.1 - 4.4e-06 26.1 0.1 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM84632.1 - 1.7e-05 24.8 0.3 0.46 10.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EIM84632.1 - 5.3e-05 23.6 0.0 0.02 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM84632.1 - 0.0015 18.6 0.0 9 6.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EIM84632.1 - 0.0021 17.5 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EIM84632.1 - 0.0045 16.4 0.1 4 6.8 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.12 EIM84632.1 - 0.0047 16.7 0.2 0.017 14.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 EIM84632.1 - 0.0075 16.0 0.9 1.1 9.0 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain RseC_MucC PF04246.7 EIM84632.1 - 0.029 13.9 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 1 0 Positive regulator of sigma(E), RseC/MucC AAA_17 PF13207.1 EIM84632.1 - 0.035 14.9 0.0 7.3 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIM84632.1 - 0.04 13.6 0.0 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EIM84632.1 - 0.048 13.9 0.1 12 6.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIM84632.1 - 0.05 13.5 0.1 3 7.8 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EIM84632.1 - 0.087 12.5 0.6 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EIM84632.1 - 0.15 11.8 0.0 7.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EIM84632.1 - 0.17 11.7 0.3 25 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIM84632.1 - 0.29 10.3 0.0 23 4.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 EIM84632.1 - 1.6 8.1 3.1 14 5.0 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Reo_sigmaC PF04582.7 EIM84633.1 - 0.00068 18.9 1.3 0.00077 18.7 0.9 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC144C PF14915.1 EIM84633.1 - 0.0015 17.5 2.0 0.0017 17.3 1.4 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF4611 PF15387.1 EIM84633.1 - 0.019 15.0 0.4 0.03 14.4 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) TraC PF07820.7 EIM84633.1 - 0.041 14.0 0.3 0.062 13.5 0.2 1.3 1 0 0 1 1 1 0 TraC-like protein CCDC92 PF14916.1 EIM84633.1 - 0.048 13.2 0.4 0.097 12.2 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF2968 PF11180.3 EIM84633.1 - 0.054 12.8 1.7 0.072 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1192 PF06698.6 EIM84633.1 - 0.065 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Herpes_BLRF2 PF05812.7 EIM84633.1 - 0.099 12.4 3.0 0.14 11.9 2.1 1.5 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 EIM84633.1 - 0.11 12.4 1.2 0.21 11.5 0.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Sec2p PF06428.6 EIM84633.1 - 0.12 12.2 2.3 0.16 11.8 1.6 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ADIP PF11559.3 EIM84633.1 - 0.14 12.0 4.0 0.2 11.5 2.7 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EIM84633.1 - 0.15 12.1 3.7 0.2 11.7 2.6 1.1 1 0 0 1 1 1 0 DivIVA protein HALZ PF02183.13 EIM84633.1 - 0.28 10.9 2.3 0.45 10.2 0.7 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EIM84633.1 - 0.28 11.0 5.0 0.18 11.6 0.6 2.3 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EIM84633.1 - 0.31 11.0 3.5 0.44 10.5 1.9 1.6 2 0 0 2 2 2 0 bZIP transcription factor DUF2205 PF10224.4 EIM84633.1 - 0.86 9.2 4.0 1.2 8.7 1.6 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DEAD PF00270.24 EIM84638.1 - 4e-05 23.1 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM84638.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain ResIII PF04851.10 EIM84638.1 - 0.022 14.5 0.1 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HNH_2 PF13391.1 EIM84642.1 - 2.3e-05 24.1 0.1 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease MR_MLE_C PF13378.1 EIM84643.1 - 1.2e-17 63.8 0.2 2.3e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIM84643.1 - 8.2e-12 45.4 0.2 5.2e-11 42.9 0.0 2.4 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIM84643.1 - 7.2e-08 32.4 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.11 EIM84644.1 - 2e-30 105.6 33.3 3.4e-30 104.9 21.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EIM84644.1 - 1.8 8.0 7.0 0.46 10.0 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) PsbN PF02468.10 EIM84644.1 - 9.5 5.9 7.5 12 5.5 0.5 3.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Aminotran_1_2 PF00155.16 EIM84645.1 - 1.4e-16 60.4 0.0 7e-16 58.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIM84645.1 - 0.0052 15.8 0.0 0.012 14.6 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Activator-TraM PF11657.3 EIM84645.1 - 0.0089 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator TraM COesterase PF00135.23 EIM84646.1 - 4.8e-72 243.3 0.0 6.3e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM84646.1 - 0.0014 18.2 0.1 0.023 14.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 EIM84647.1 - 1.6e-13 50.1 1.3 2.7e-13 49.4 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM84647.1 - 1.5e-06 27.9 7.1 3e-06 27.0 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHAT PF12770.2 EIM84649.1 - 4.1e-37 127.8 0.0 6.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM84649.1 - 8.8e-37 124.9 14.5 0.0011 18.8 0.0 12.9 5 4 9 14 14 14 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIM84649.1 - 6.1e-31 105.8 9.8 3.1e-05 23.5 0.0 10.6 4 3 8 12 12 12 7 TPR repeat TPR_2 PF07719.12 EIM84649.1 - 1.4e-10 40.2 10.4 3.3 7.8 0.0 12.1 14 0 0 14 14 12 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84649.1 - 1.9e-10 41.0 15.5 0.095 13.3 0.1 9.2 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM84649.1 - 1.6e-07 31.3 14.3 3.9 8.3 0.0 9.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM84649.1 - 2.9e-06 26.6 15.8 1.7 8.3 0.0 10.8 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM84649.1 - 5.2e-06 26.2 2.0 0.4 11.0 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84649.1 - 5.7e-06 25.7 1.5 10 6.1 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM84649.1 - 2e-05 24.0 11.0 2.4 8.1 0.0 9.3 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM84649.1 - 0.021 15.1 9.3 12 6.3 0.0 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat GDE_N PF12439.3 EIM84649.1 - 0.021 14.0 0.0 28 3.8 0.0 4.0 2 2 1 3 3 3 0 Glycogen debranching enzyme N terminal Sel1 PF08238.7 EIM84649.1 - 0.045 14.3 0.0 1.1e+02 3.6 0.0 5.0 5 0 0 5 5 5 0 Sel1 repeat Peptidase_S10 PF00450.17 EIM84650.1 - 1.1e-85 288.3 0.0 1.3e-85 288.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.27 EIM84651.1 - 4.6e-74 241.8 37.0 4.1e-13 48.6 0.7 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EIM84651.1 - 5.6e-07 29.6 8.9 0.14 12.4 0.0 5.9 3 2 3 6 6 6 3 PQQ-like domain PD40 PF07676.7 EIM84651.1 - 3.3e-06 26.6 1.1 4.1 7.1 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIM84651.1 - 0.00049 19.3 5.1 46 3.4 0.0 5.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.1 EIM84651.1 - 0.00051 20.0 0.1 0.0031 17.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EIM84651.1 - 0.0006 19.5 0.2 0.0016 18.1 0.1 1.7 1 1 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 EIM84651.1 - 0.0029 16.4 8.0 21 3.7 0.0 5.6 2 2 3 6 6 6 0 Nup133 N terminal like Peptidase_S9_N PF02897.10 EIM84651.1 - 0.013 14.0 0.4 17 3.8 0.0 3.7 1 1 3 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF815 PF05673.8 EIM84651.1 - 0.051 12.4 0.0 8.7 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 EIM84651.1 - 0.055 13.6 0.1 0.36 11.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIM84651.1 - 0.12 11.4 0.0 0.33 10.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EIM84651.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 EIM84651.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.11 EIM84651.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EIM84651.1 - 0.31 10.7 0.0 1.1 8.9 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase Peptidase_S10 PF00450.17 EIM84653.1 - 2.7e-08 33.3 0.0 3.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.17 EIM84654.1 - 1.7e-60 204.9 0.0 1.4e-59 201.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pox_D5 PF03288.11 EIM84654.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like SKG6 PF08693.5 EIM84657.1 - 0.0002 20.5 0.4 0.00041 19.5 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fil_haemagg PF05594.9 EIM84657.1 - 0.37 11.1 13.1 0.1 12.9 3.8 2.8 2 1 0 2 2 2 0 Haemagluttinin repeat BTB PF00651.26 EIM84659.1 - 0.00048 20.0 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Aldolase_II PF00596.16 EIM84660.1 - 3.1e-27 95.3 0.2 4.8e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAA_hydrolase PF01557.13 EIM84661.1 - 2.6e-50 170.8 0.1 4.2e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4124 PF13511.1 EIM84661.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) adh_short PF00106.20 EIM84663.1 - 6.8e-16 58.6 0.7 1.2e-15 57.8 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84663.1 - 6.4e-11 42.4 0.1 9.4e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM84663.1 - 5.1e-08 33.1 0.3 3.5e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM84663.1 - 6.8e-06 25.8 2.3 3.7e-05 23.4 1.6 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM84663.1 - 0.0012 18.2 0.1 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84663.1 - 0.0055 15.9 0.4 0.009 15.2 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EIM84663.1 - 0.023 14.7 0.2 0.035 14.0 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Transp_cyt_pur PF02133.10 EIM84664.1 - 1.9e-77 260.6 29.8 2.3e-77 260.4 20.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LamB_YcsF PF03746.11 EIM84665.1 - 2e-72 243.1 0.0 2.4e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family JmjN PF02375.12 EIM84665.1 - 0.18 11.3 1.8 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 jmjN domain PolyA_pol_arg_C PF12626.2 EIM84666.1 - 0.059 13.0 2.9 0.14 11.8 2.0 1.6 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus AHS2 PF02626.10 EIM84669.1 - 1.1e-74 251.1 0.0 1.6e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EIM84669.1 - 5.7e-54 182.6 0.0 1e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EIM84669.1 - 1.6e-34 119.1 0.0 2.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EIM84669.1 - 1.9e-28 98.7 0.0 8.1e-28 96.7 0.0 2.1 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIM84669.1 - 5.1e-22 77.8 0.0 1.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EIM84669.1 - 1.5e-15 57.3 0.0 9.2e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EIM84669.1 - 4.8e-11 42.1 2.2 4.8e-11 42.1 1.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EIM84669.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.14 EIM84669.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EIM84669.1 - 0.043 13.2 0.0 0.23 10.9 0.0 2.1 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIM84669.1 - 0.15 11.7 5.7 0.43 10.2 1.1 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like adh_short PF00106.20 EIM84670.1 - 6.6e-15 55.4 0.3 1.1e-14 54.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84670.1 - 3e-08 33.7 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM84670.1 - 2.6e-05 23.9 0.3 3.7e-05 23.4 0.2 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM84670.1 - 0.00019 21.4 0.2 0.00058 19.9 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM84670.1 - 0.00021 20.8 0.0 0.00026 20.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM84670.1 - 0.00047 19.4 0.1 0.00081 18.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EIM84670.1 - 0.00088 19.2 0.1 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 EIM84670.1 - 0.046 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIM84670.1 - 0.057 12.1 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ecm33 PF12454.3 EIM84673.1 - 0.081 12.8 0.5 0.31 10.9 0.3 2.0 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Lir1 PF07207.6 EIM84673.1 - 1.6 8.9 6.0 0.42 10.8 1.3 1.9 1 1 1 2 2 2 0 Light regulated protein Lir1 Lactamase_B_2 PF12706.2 EIM84674.1 - 9.7e-21 74.2 0.2 1.4e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM84674.1 - 1.5e-08 34.4 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cu_amine_oxid PF01179.15 EIM84675.1 - 5.3e-113 377.8 5.9 6.6e-113 377.5 4.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EIM84675.1 - 3.1e-21 75.0 2.1 6.7e-21 73.9 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EIM84675.1 - 4.6e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 EIM84676.1 - 1.2e-115 386.7 20.8 1.3e-115 386.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM84676.1 - 2.4e-24 85.7 26.6 2.4e-24 85.7 18.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.1 EIM84677.1 - 0.08 12.7 3.7 2.1 8.1 0.0 4.2 4 2 0 4 4 4 0 Leucine rich repeat WD40 PF00400.27 EIM84678.1 - 6.4e-24 82.9 7.3 1.9e-08 33.8 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nbas_N PF15492.1 EIM84678.1 - 8.4e-05 21.8 0.0 0.076 12.1 0.0 2.9 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DUF2163 PF09931.4 EIM84679.1 - 0.11 12.2 0.5 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) NVEALA PF14055.1 EIM84679.1 - 0.18 11.5 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 NVEALA protein F-box-like PF12937.2 EIM84680.1 - 1.8e-08 33.9 1.3 5.9e-08 32.3 0.4 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM84680.1 - 0.0035 16.9 3.5 0.75 9.4 1.9 4.5 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) TatD_DNase PF01026.16 EIM84685.1 - 3.1e-43 147.8 0.0 3.7e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EIM84685.1 - 0.00011 21.8 0.1 0.00083 18.9 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Zn_clus PF00172.13 EIM84686.1 - 0.00056 19.7 21.5 0.15 11.9 4.3 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain UCR_UQCRX_QCR9 PF05365.7 EIM84687.1 - 0.012 15.2 0.2 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like UCR_UQCRX_QCR9 PF05365.7 EIM84688.1 - 0.011 15.3 0.3 0.016 14.7 0.2 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF1212 PF06738.7 EIM84691.1 - 1.9e-46 157.9 6.7 3.2e-43 147.4 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM84691.1 - 3e-18 65.9 5.2 3e-18 65.9 3.6 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Hydantoinase_A PF01968.13 EIM84692.1 - 5e-86 288.4 2.3 5e-85 285.1 0.3 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EIM84692.1 - 1.9e-70 237.6 0.0 2.6e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EIM84692.1 - 9.6e-42 142.4 0.1 6.6e-38 129.9 0.0 3.4 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIM84692.1 - 8.8e-05 21.0 3.3 0.11 10.7 0.1 2.5 3 0 0 3 3 3 2 MutL protein Phytoreo_P8 PF07124.6 EIM84692.1 - 0.18 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DUF1672 PF07901.6 EIM84694.1 - 0.098 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) NmrA PF05368.8 EIM84695.1 - 7.6e-22 77.7 0.0 1.8e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM84695.1 - 1.4e-13 51.2 0.0 2.5e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EIM84695.1 - 0.017 15.0 0.0 0.042 13.7 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EIM84695.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 EIM84696.1 - 5.7e-23 81.3 0.0 1.5e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM84696.1 - 1.8e-11 44.3 0.1 3.4e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM84696.1 - 0.01 15.5 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EIM84696.1 - 0.019 14.9 0.7 0.031 14.1 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EIM84696.1 - 0.029 14.3 0.1 0.11 12.3 0.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EIM84696.1 - 0.11 11.8 0.2 0.53 9.6 0.2 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family HMG_box PF00505.14 EIM84697.1 - 6.1e-13 48.8 0.0 7.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM84697.1 - 0.00087 19.6 0.0 0.0011 19.3 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain UNC-93 PF05978.11 EIM84698.1 - 4.4e-14 52.2 9.2 4.4e-14 52.2 6.4 3.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EIM84698.1 - 6e-14 51.5 48.0 1.2e-13 50.5 31.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PrgI PF12666.2 EIM84698.1 - 0.92 9.6 0.0 0.92 9.6 0.0 4.9 6 0 0 6 6 6 0 PrgI family protein HAMP PF00672.20 EIM84699.1 - 6e-45 151.2 16.5 7.3e-08 32.4 0.1 7.5 8 0 0 8 8 8 6 HAMP domain HATPase_c PF02518.21 EIM84699.1 - 1.3e-28 98.9 0.0 5.1e-28 97.0 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM84699.1 - 4.7e-24 84.5 0.0 8.7e-23 80.4 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIM84699.1 - 5.7e-17 61.4 0.7 2.9e-16 59.2 0.5 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AcylCoA_dehyd_C PF12186.3 EIM84699.1 - 4.9e-05 23.1 6.8 8.9 6.2 0.0 6.1 6 0 0 6 6 6 2 Acyl-CoA dehydrogenase C terminal DNA_binding_1 PF01035.15 EIM84700.1 - 2.8e-12 46.2 0.0 3.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HNH PF01844.18 EIM84701.1 - 0.00073 19.3 3.0 0.0036 17.1 2.1 2.1 1 1 0 1 1 1 1 HNH endonuclease C1_1 PF00130.17 EIM84701.1 - 0.027 14.1 1.4 0.065 12.9 0.7 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Solute_trans_a PF03619.11 EIM84702.1 - 2.3e-70 237.0 18.7 2.7e-70 236.8 13.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FAM163 PF15069.1 EIM84702.1 - 0.088 13.3 0.1 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 FAM163 family DUF2763 PF10961.3 EIM84702.1 - 0.2 12.0 0.5 4.5 7.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) SUR7 PF06687.7 EIM84702.1 - 6.3 6.2 10.6 0.78 9.2 1.7 2.7 2 1 1 3 3 3 0 SUR7/PalI family F-box-like PF12937.2 EIM84704.1 - 4.5e-06 26.2 0.9 1.2e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like Ank_2 PF12796.2 EIM84705.1 - 4.3e-16 59.0 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM84705.1 - 3.8e-14 51.6 0.4 5.4e-08 32.2 0.3 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIM84705.1 - 9e-11 41.9 0.1 3.2e-05 24.3 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM84705.1 - 1.3e-10 41.1 0.5 8.7e-07 29.0 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM84705.1 - 1.3e-09 37.3 0.0 4.3e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat PLDc PF00614.17 EIM84706.1 - 1.4e-15 56.4 8.4 1e-08 34.6 0.2 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIM84706.1 - 4.5e-12 45.8 0.0 1.3e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain F-box-like PF12937.2 EIM84707.1 - 2.3e-09 36.8 3.7 1.5e-08 34.1 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM84707.1 - 0.039 13.6 3.9 0.57 9.9 0.0 3.4 3 0 0 3 3 3 0 F-box domain HECT PF00632.20 EIM84708.1 - 8.5e-91 304.3 0.0 1.1e-90 303.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIM84708.1 - 8.3e-34 115.0 16.8 3.9e-11 42.6 0.3 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIM84708.1 - 7.1e-15 54.6 0.0 1.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain F-box-like PF12937.2 EIM84709.1 - 6.3e-08 32.2 0.1 1.4e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM84709.1 - 2.6 7.8 5.8 4.5 7.1 0.0 3.9 4 2 0 4 4 4 0 Leucine rich repeat DUF4448 PF14610.1 EIM84710.1 - 4.3e-16 58.9 0.1 6.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.8 EIM84710.1 - 0.048 12.2 0.2 0.08 11.5 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein GPI-anchored PF10342.4 EIM84710.1 - 0.074 13.5 4.8 0.21 12.0 0.8 2.6 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FmdA_AmdA PF03069.10 EIM84712.1 - 1.4e-56 191.8 0.0 2.7e-32 111.9 0.1 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family Nup84_Nup100 PF04121.8 EIM84713.1 - 2.7e-79 266.6 0.0 1.3e-39 135.5 0.1 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 CSTF2_hinge PF14327.1 EIM84713.1 - 0.057 13.5 1.3 4.3 7.4 0.0 3.8 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 Abhydrolase_6 PF12697.2 EIM84714.1 - 1.6e-16 60.8 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM84714.1 - 1e-06 28.4 0.0 4.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM84714.1 - 3.9e-05 23.4 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM84714.1 - 0.00074 18.7 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EIM84714.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EIM84714.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 EIM84715.1 - 1.7e-21 77.1 0.0 2.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM84715.1 - 2.2e-10 40.4 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM84715.1 - 5.6e-08 32.6 0.0 1.3e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM84715.1 - 5.5e-05 22.4 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EIM84715.1 - 7.6e-05 22.2 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 EIM84715.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EIM84715.1 - 0.045 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Cyclase PF04199.8 EIM84716.1 - 4.3e-37 127.4 0.2 4.8e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 Putative cyclase PyrI_C PF02748.10 EIM84717.1 - 0.04 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FAD_binding_4 PF01565.18 EIM84718.1 - 9.3e-28 96.4 7.8 1.4e-27 95.8 4.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EIM84718.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like BRCA2 PF00634.13 EIM84718.1 - 0.13 11.5 0.3 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 BRCA2 repeat MutL_C PF08676.6 EIM84719.1 - 0.0024 17.4 0.3 0.0048 16.5 0.2 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain zf-RING_2 PF13639.1 EIM84720.1 - 5.3e-09 35.7 12.5 9e-09 35.0 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM84720.1 - 6.6e-06 26.1 8.3 1.5e-05 25.0 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIM84720.1 - 6.8e-06 25.6 12.2 1.1e-05 24.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM84720.1 - 7.7e-06 25.8 13.5 1.3e-05 25.1 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM84720.1 - 0.00021 20.9 14.0 0.00032 20.3 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM84720.1 - 0.29 10.8 15.2 0.48 10.1 10.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM84720.1 - 0.67 9.8 12.2 1.3 8.9 8.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EIM84720.1 - 6.3 6.3 12.0 12 5.4 8.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger Homeobox PF00046.24 EIM84721.1 - 1.6e-14 53.2 1.0 3.1e-14 52.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM84721.1 - 0.23 11.1 1.6 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain SPC12 PF06645.8 EIM84722.1 - 4.3e-22 77.6 0.1 4.9e-22 77.5 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Plasmod_dom_1 PF09715.5 EIM84722.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Cadherin_C PF01049.12 EIM84724.1 - 0.038 14.0 0.4 0.06 13.3 0.3 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region BTB PF00651.26 EIM84725.1 - 1.6e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Bromodomain PF00439.20 EIM84726.1 - 2.6e-17 62.4 0.0 5.6e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain RicinB_lectin_2 PF14200.1 EIM84727.1 - 1.2e-27 96.3 2.6 1.1e-16 61.0 0.8 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIM84727.1 - 1.3e-07 31.6 0.0 0.015 15.3 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIM84728.1 - 1.1e-05 25.7 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.1 EIM84729.1 - 1.8e-13 50.7 0.5 1.4e-07 31.8 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIM84729.1 - 0.0061 16.5 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIM84730.1 - 1.1e-06 28.9 0.9 1.6e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF455 PF04305.9 EIM84731.1 - 6.4e-92 307.3 0.1 8.6e-92 306.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EIM84731.1 - 8.1e-09 34.9 0.0 3.2e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EIM84731.1 - 0.00013 21.5 0.0 0.00036 20.2 0.0 1.8 1 1 1 2 2 2 1 Rieske-like [2Fe-2S] domain TauD PF02668.11 EIM84732.1 - 2.7e-44 151.7 0.0 3.5e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DNA_mis_repair PF01119.14 EIM84733.1 - 2.3e-19 69.0 0.0 8.1e-19 67.2 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EIM84733.1 - 5.1e-18 65.0 0.8 4.3e-14 52.3 0.4 2.8 2 1 0 2 2 2 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EIM84733.1 - 1.2e-13 50.8 0.1 5.2e-13 48.8 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIM84733.1 - 9.2e-13 47.8 0.1 4.6e-12 45.6 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2945 PF11160.3 EIM84734.1 - 0.11 12.3 2.4 0.17 11.7 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) Pkinase PF00069.20 EIM84736.1 - 5.9e-18 64.9 0.1 4.2e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EIM84736.1 - 3.1e-07 29.9 2.0 0.0081 15.5 0.0 2.8 2 1 0 2 2 2 2 RIO1 family APH PF01636.18 EIM84736.1 - 2.5e-06 27.4 0.0 0.04 13.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIM84737.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM84737.1 - 0.0031 17.3 0.5 0.0084 15.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM84737.1 - 0.0078 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EIM84737.1 - 0.039 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_transf_15 PF01793.11 EIM84738.1 - 1.3e-136 454.9 12.1 1.5e-136 454.7 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Fic PF02661.13 EIM84739.1 - 1.7e-08 35.0 0.0 3.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Peptidase_S64 PF08192.6 EIM84740.1 - 0.18 10.1 0.0 0.27 9.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sec7_N PF12783.2 EIM84741.1 - 1.3e-33 115.7 0.0 1.9e-32 112.0 0.0 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIM84741.1 - 4.3e-05 22.9 0.1 0.00025 20.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) EVC2_like PF12297.3 EIM84741.1 - 0.12 10.9 0.2 0.21 10.1 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase PF00069.20 EIM84742.1 - 3.2e-06 26.4 0.0 5.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM84742.1 - 0.0016 17.8 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM84742.1 - 0.0093 15.7 0.5 0.017 14.8 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIM84742.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EIM84743.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM84743.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM84743.1 - 0.015 14.6 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EIM84745.1 - 1.3e-70 237.5 0.0 6.1e-70 235.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84745.1 - 3.4e-36 124.6 0.0 7.4e-36 123.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EIM84745.1 - 2.7e-15 55.5 0.0 4.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EIM84745.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM84745.1 - 0.00034 20.4 0.1 0.0017 18.1 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM84745.1 - 0.00051 19.0 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 EIM84745.1 - 0.011 15.0 0.3 0.017 14.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EIM84745.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EIM84747.1 - 2.5e-06 26.8 0.0 3.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM84747.1 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM84747.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIM84748.1 - 4.2e-08 32.6 0.0 7.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM84748.1 - 0.00041 20.1 0.1 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM84748.1 - 0.00093 18.5 0.1 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rad60-SLD PF11976.3 EIM84749.1 - 6.1e-24 83.5 0.4 8.3e-24 83.0 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIM84749.1 - 3e-10 39.3 0.1 4.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Cadherin-like PF12733.2 EIM84749.1 - 0.0023 18.1 2.4 0.11 12.7 0.2 2.6 1 1 1 2 2 2 2 Cadherin-like beta sandwich domain IncA PF04156.9 EIM84751.1 - 0.051 13.1 0.1 0.051 13.1 0.1 2.5 1 1 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EIM84751.1 - 0.056 13.8 1.5 0.46 10.9 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TraC_F_IV PF11130.3 EIM84751.1 - 0.064 12.6 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer TEX13 PF15186.1 EIM84751.1 - 0.073 12.6 0.1 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Lebercilin PF15619.1 EIM84751.1 - 0.077 12.4 0.7 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_capsid PF06112.6 EIM84751.1 - 1.9 8.4 11.4 3.8 7.5 1.8 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SNF2_N PF00176.18 EIM84752.1 - 1.5e-70 237.4 0.1 1.6e-69 233.9 0.1 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM84752.1 - 3.9e-14 52.2 0.0 1.2e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM84752.1 - 1e-05 25.4 0.0 0.14 12.0 0.1 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EIM84752.1 - 0.0016 17.3 0.0 0.014 14.1 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ITAM PF02189.10 EIM84752.1 - 0.037 14.3 0.4 0.33 11.3 0.0 2.6 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif PD40 PF07676.7 EIM84755.1 - 3.1e-33 112.8 21.3 2.3e-09 36.7 0.9 8.9 9 0 0 9 9 9 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EIM84755.1 - 7.8e-05 21.4 14.4 2.2 6.8 0.0 6.8 4 2 2 7 7 7 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EIM84755.1 - 0.0014 18.3 2.9 0.14 11.8 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Aa_trans PF01490.13 EIM84756.1 - 3.4e-33 114.7 39.0 4e-33 114.5 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 EIM84757.1 - 9.8e-07 28.1 0.0 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM84757.1 - 0.00083 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM84757.1 - 0.0038 16.5 0.1 0.0091 15.3 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EIM84758.1 - 3.4e-06 26.4 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM84758.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM84758.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIM84759.1 - 9.6e-09 34.7 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM84759.1 - 3.1e-05 23.8 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM84759.1 - 0.00032 20.1 0.0 0.00075 18.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF4566 PF15130.1 EIM84759.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Macoilin PF09726.4 EIM84760.1 - 7.5 4.6 16.9 9.2 4.4 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein GST_N_3 PF13417.1 EIM84761.1 - 2.8e-12 46.6 0.2 5.6e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM84761.1 - 2.9e-05 23.8 0.1 6.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM84761.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cpn10 PF00166.16 EIM84761.1 - 0.077 12.9 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit F-box-like PF12937.2 EIM84762.1 - 8.1e-07 28.6 3.8 1.2e-06 28.1 0.6 2.7 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 EIM84763.1 - 3.2e-10 39.5 0.5 1e-09 37.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM84763.1 - 0.042 13.5 5.9 0.43 10.3 4.1 2.4 1 1 0 1 1 1 0 F-box domain 2OG-FeII_Oxy_2 PF13532.1 EIM84764.1 - 6.5e-23 81.5 0.0 8.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM84764.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 EIM84765.1 - 6.6e-05 22.5 0.1 0.00018 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM84765.1 - 0.0064 16.1 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain SnoaL_4 PF13577.1 EIM84766.1 - 4.7e-05 23.3 0.0 6.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EIM84766.1 - 5.1e-05 23.6 0.1 6.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EIM84766.1 - 0.066 13.2 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.15 EIM84766.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Phosphodiest PF01663.17 EIM84767.1 - 9.6e-11 41.5 1.5 2.1e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EIM84767.1 - 0.00074 18.9 0.7 0.0013 18.2 0.5 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily CcmD PF04995.9 EIM84767.1 - 0.0038 16.9 0.2 0.016 14.9 0.1 2.1 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Sulfatase PF00884.18 EIM84767.1 - 0.019 14.1 0.3 0.019 14.1 0.2 2.0 2 1 0 3 3 3 0 Sulfatase cNMP_binding PF00027.24 EIM84768.1 - 1.3e-36 124.2 0.1 1.1e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIM84768.1 - 1.6e-08 33.7 0.3 2.4e-07 30.0 0.1 2.4 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit hNIFK_binding PF12196.3 EIM84768.1 - 0.012 15.0 0.1 0.066 12.5 0.0 2.1 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK DUF3783 PF12646.2 EIM84768.1 - 0.099 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) AAA PF00004.24 EIM84770.1 - 7.1e-19 68.3 0.0 2.1e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM84770.1 - 0.012 15.3 0.2 0.046 13.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM84770.1 - 0.028 14.5 0.0 0.14 12.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 EIM84770.1 - 0.052 13.1 0.1 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIM84770.1 - 0.059 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 EIM84770.1 - 0.081 12.8 0.0 0.64 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EIM84770.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EIM84770.1 - 0.11 13.3 0.2 0.93 10.3 0.0 2.6 2 2 0 2 2 2 0 AAA domain Topoisom_I_N PF02919.10 EIM84770.1 - 0.44 9.8 3.7 0.75 9.0 2.5 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AAA PF00004.24 EIM84771.1 - 6.6e-19 68.4 0.0 2.5e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM84771.1 - 0.0036 17.4 0.0 0.12 12.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM84771.1 - 0.017 14.8 0.1 0.072 12.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM84771.1 - 0.035 14.1 0.1 0.62 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 EIM84771.1 - 0.039 13.5 0.0 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIM84771.1 - 0.04 14.7 0.1 0.18 12.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIM84771.1 - 0.06 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EIM84771.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EIM84771.1 - 0.085 12.5 0.1 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase Prenyltrans PF00432.16 EIM84772.1 - 2.7e-58 193.1 5.8 2.7e-12 46.0 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIM84772.1 - 6.4e-29 100.6 0.0 9.7e-15 54.9 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIM84772.1 - 1.2e-08 34.8 0.0 1.9e-05 24.6 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like Rop PF01815.11 EIM84772.1 - 0.11 11.9 2.2 3.5 7.1 0.0 3.3 4 0 0 4 4 4 0 Rop protein ITAM_Cys-rich PF10538.4 EIM84774.1 - 0.26 10.8 1.4 0.67 9.5 0.9 1.7 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Asp PF00026.18 EIM84778.1 - 0.00075 18.8 0.0 0.34 10.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM84778.1 - 0.0017 18.8 0.0 1.9 9.0 0.0 3.7 4 0 0 4 4 4 2 Aspartyl protease FGGY_C PF02782.11 EIM84779.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Rhodanese PF00581.15 EIM84781.1 - 3.5e-05 24.0 0.0 6.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ANTAR PF03861.9 EIM84781.1 - 0.009 15.5 0.1 0.075 12.6 0.1 2.2 2 0 0 2 2 2 1 ANTAR domain Terminase_5 PF06056.7 EIM84782.1 - 0.052 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Alpha_L_fucos PF01120.12 EIM84783.1 - 1.2e-76 257.9 0.7 1.3e-75 254.4 0.5 2.0 1 1 0 1 1 1 1 Alpha-L-fucosidase Fungal_trans PF04082.13 EIM84785.1 - 1e-17 63.8 1.2 2e-17 62.9 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM84785.1 - 0.00016 21.5 11.1 0.00025 20.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.2 EIM84786.1 - 0.00017 21.9 0.0 0.00021 21.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EIM84786.1 - 0.00023 21.0 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EIM84786.1 - 0.038 14.3 0.0 0.051 13.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain FGGY_N PF00370.16 EIM84787.1 - 6.6e-05 22.3 0.0 0.0054 16.0 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box PF00646.28 EIM84789.1 - 3e-07 29.9 0.3 9e-07 28.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM84789.1 - 0.00017 21.2 0.3 0.00059 19.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like GMC_oxred_C PF05199.8 EIM84790.1 - 1e-34 119.8 0.0 1.7e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIM84791.1 - 4.3e-27 95.0 0.0 4.6e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DUF1348 PF07080.6 EIM84793.1 - 2.9e-58 195.7 4.4 3.5e-58 195.4 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EIM84793.1 - 1.7e-06 28.3 0.2 2.4e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EIM84793.1 - 0.0028 17.8 0.1 0.0058 16.8 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) MFS_1 PF07690.11 EIM84794.1 - 2e-34 118.8 29.9 2e-34 118.8 20.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.16 EIM84795.1 - 3.3e-17 62.7 0.0 5.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM84795.1 - 6.9e-14 51.2 0.0 2e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM84795.1 - 1.1e-13 50.7 0.1 2.6e-12 46.1 0.1 2.7 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EIM84795.1 - 9e-11 42.1 0.3 2e-10 40.9 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM84795.1 - 2.6e-05 23.5 0.2 4.3e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM84795.1 - 0.00038 20.4 1.9 0.00097 19.0 1.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM84795.1 - 0.0065 15.3 0.0 0.76 8.6 0.0 2.5 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM84795.1 - 0.074 11.9 1.1 0.65 8.8 0.7 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein ABM PF03992.11 EIM84796.1 - 1.1e-08 34.9 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.11 EIM84797.1 - 3.5e-09 36.5 0.1 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FMO-like PF00743.14 EIM84798.1 - 1.1e-14 53.5 0.5 8.2e-10 37.4 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM84798.1 - 2.1e-09 36.7 0.2 1.7e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIM84798.1 - 3.6e-09 36.9 0.8 5.5e-06 26.5 0.0 3.1 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM84798.1 - 3.8e-09 36.7 0.0 1.5e-06 28.2 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM84798.1 - 5.1e-05 21.9 0.6 0.00097 17.7 0.5 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EIM84798.1 - 0.00014 21.0 0.3 0.00024 20.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIM84798.1 - 0.00058 18.8 0.3 0.037 12.9 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIM84798.1 - 0.0018 18.0 0.1 0.67 9.7 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIM84798.1 - 0.0073 15.1 1.7 0.0078 15.0 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain THF_DHG_CYH_C PF02882.14 EIM84798.1 - 0.012 14.7 0.0 0.25 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GIDA PF01134.17 EIM84798.1 - 0.013 14.4 0.2 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF498 PF04430.9 EIM84798.1 - 0.019 14.5 0.0 0.17 11.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) Thi4 PF01946.12 EIM84798.1 - 0.022 13.8 0.4 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EIM84798.1 - 0.035 14.1 0.6 0.08 12.9 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM84798.1 - 0.043 12.7 2.4 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIM84798.1 - 0.053 13.7 0.0 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EIM84798.1 - 0.065 13.6 0.0 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM84798.1 - 0.1 12.7 0.3 3.9 7.5 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IBR PF01485.16 EIM84799.1 - 7.2e-13 48.2 26.4 3.4e-09 36.4 3.7 4.4 4 1 0 4 4 4 3 IBR domain NUDIX_2 PF13869.1 EIM84800.1 - 6e-85 283.3 0.0 6.8e-85 283.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M36 PF02128.10 EIM84801.1 - 9.9e-134 445.9 7.5 2.5e-133 444.5 5.2 1.6 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIM84801.1 - 5e-09 35.4 0.8 9.6e-09 34.5 0.6 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EIM84801.1 - 0.05 13.3 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Ras PF00071.17 EIM84802.1 - 4.5e-56 188.6 0.1 8.4e-56 187.8 0.0 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EIM84802.1 - 1.5e-18 67.4 0.0 4.7e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM84802.1 - 4.4e-15 55.3 0.0 5.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM84802.1 - 3.1e-07 29.7 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM84802.1 - 3.5e-06 26.9 0.0 1e-05 25.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM84802.1 - 0.00021 20.7 0.0 0.00046 19.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EIM84802.1 - 0.012 15.6 0.3 0.47 10.4 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 EIM84802.1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EIM84802.1 - 0.049 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 EIM84802.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIM84802.1 - 0.13 11.8 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EIM84802.1 - 0.17 10.5 1.3 3.1 6.3 0.2 2.1 1 1 0 2 2 2 0 G-protein alpha subunit Epimerase PF01370.16 EIM84803.1 - 6.3e-18 65.0 0.0 2.7e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM84803.1 - 4.1e-15 55.2 0.0 5.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM84803.1 - 1e-13 51.7 0.6 1.9e-13 50.8 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM84803.1 - 4.2e-12 45.5 0.0 1.4e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM84803.1 - 1.8e-06 27.3 0.4 3.1e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM84803.1 - 0.00055 19.8 1.4 0.0042 17.0 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM84803.1 - 0.0016 17.3 0.0 0.38 9.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM84803.1 - 0.0021 17.0 0.0 0.02 13.8 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EIM84803.1 - 0.014 14.4 0.1 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 EIM84803.1 - 0.063 12.9 0.2 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 KR domain F-box-like PF12937.2 EIM84804.1 - 1.4e-07 31.1 0.3 1.4e-07 31.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like PARP PF00644.15 EIM84805.1 - 6.4e-16 58.4 2.0 6.4e-12 45.3 0.1 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Dak1_2 PF13684.1 EIM84806.1 - 0.096 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family fn2 PF00040.14 EIM84806.1 - 0.11 12.5 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type II domain Sulfate_transp PF00916.15 EIM84807.1 - 1.9e-47 161.6 6.1 2e-47 161.5 1.7 2.2 1 1 1 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EIM84807.1 - 2.3e-13 49.7 0.0 4.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EIM84807.1 - 6.1e-10 38.5 0.0 1.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain F-box-like PF12937.2 EIM84810.1 - 4.1e-07 29.6 0.4 1.1e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM84810.1 - 0.017 14.7 0.4 0.054 13.1 0.3 1.8 1 0 0 1 1 1 0 F-box domain Zip PF02535.17 EIM84811.1 - 4.6e-47 160.5 18.9 1.7e-44 152.1 13.1 3.1 1 1 0 1 1 1 1 ZIP Zinc transporter Inhibitor_I9 PF05922.11 EIM84812.1 - 3.3e-08 33.9 0.0 3.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 OCD_Mu_crystall PF02423.10 EIM84813.1 - 7.8e-27 93.8 8.5 2.5e-13 49.4 0.5 2.9 1 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EIM84813.1 - 8.4e-07 29.1 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Oxidored_FMN PF00724.15 EIM84814.1 - 5e-87 292.0 0.0 7.8e-87 291.4 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIM84815.1 - 4.1e-97 325.2 0.0 4.8e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-MYND PF01753.13 EIM84816.1 - 1.9e-11 43.6 11.2 4.1e-11 42.5 7.7 1.6 1 0 0 1 1 1 1 MYND finger SGT1 PF07093.6 EIM84816.1 - 0.12 10.7 8.6 0.16 10.3 6.0 1.1 1 0 0 1 1 1 0 SGT1 protein TFIIF_alpha PF05793.7 EIM84816.1 - 5.5 5.2 19.9 8.6 4.5 13.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3643 PF12356.3 EIM84816.1 - 8.6 5.6 8.3 2.4 7.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3643) Diphthamide_syn PF01866.12 EIM84817.1 - 1.7e-74 250.8 0.0 2.7e-74 250.1 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_11 PF13414.1 EIM84818.1 - 1.1e-50 169.1 7.9 3.9e-15 55.2 0.0 7.7 4 2 5 9 9 9 8 TPR repeat TPR_1 PF00515.23 EIM84818.1 - 1.1e-40 135.6 1.7 0.00019 20.9 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIM84818.1 - 3.3e-32 107.7 9.6 0.0052 16.5 0.0 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84818.1 - 3.6e-26 91.1 11.1 4.4e-06 27.2 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EIM84818.1 - 4.4e-18 64.1 6.2 0.15 12.8 0.1 8.2 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIM84818.1 - 1.6e-17 63.2 19.0 0.001 18.9 0.4 7.7 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIM84818.1 - 8.8e-16 56.7 7.9 0.0075 16.3 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM84818.1 - 1.3e-15 57.4 8.3 0.00023 21.4 0.3 6.6 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84818.1 - 3.9e-14 51.2 1.0 1.4 8.8 0.0 8.8 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIM84818.1 - 1.7e-12 47.0 5.3 0.086 12.7 0.0 6.1 5 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EIM84818.1 - 4.3e-12 45.9 1.7 0.041 14.0 0.0 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM84818.1 - 2.2e-10 39.5 9.4 0.16 11.8 0.0 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIM84818.1 - 1e-07 31.9 12.3 0.35 11.4 0.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF3856 PF12968.2 EIM84818.1 - 3e-05 23.8 1.5 0.61 9.9 0.0 5.3 5 1 2 7 7 7 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 EIM84818.1 - 0.013 15.8 5.6 1.1 9.5 1.0 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EIM84818.1 - 0.05 13.5 3.1 2.3 8.1 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 EIM84818.1 - 0.094 11.9 8.3 6.1 6.1 0.0 4.8 6 0 0 6 6 6 0 SHNi-TPR NARP1 PF12569.3 EIM84818.1 - 0.23 10.1 9.3 0.26 10.0 0.0 3.6 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EIM84818.1 - 0.29 11.6 2.8 18 6.1 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat zf-MYND PF01753.13 EIM84819.1 - 2.2e-11 43.4 12.8 6.2e-11 41.9 8.9 1.8 1 1 0 1 1 1 1 MYND finger PAP2 PF01569.16 EIM84820.1 - 4.4e-11 42.5 8.8 8.7e-11 41.6 5.6 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EIM84820.1 - 1.6e-07 31.0 9.7 3.5e-07 29.9 6.7 1.6 1 1 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.11 EIM84821.1 - 2.2e-30 105.6 36.6 2.9e-30 105.1 25.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.5 EIM84821.1 - 0.12 12.2 2.9 0.17 11.7 0.6 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Terpene_synth_C PF03936.11 EIM84824.1 - 0.00029 20.1 0.1 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain polyprenyl_synt PF00348.12 EIM84825.1 - 1.9e-47 161.3 0.0 2.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EIM84826.1 - 6.1e-51 173.3 0.0 7.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UDPGT PF00201.13 EIM84827.1 - 8.1e-19 67.5 0.0 1.2e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.17 EIM84828.1 - 4.6e-68 229.8 0.0 3.1e-67 227.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.23 EIM84829.1 - 1.4e-23 82.4 0.4 2.7e-22 78.3 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIM84829.1 - 5.6e-10 39.6 16.8 5.6e-10 39.6 11.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1453 PF07301.6 EIM84829.1 - 0.097 12.5 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Pyr_redox_3 PF13738.1 EIM84831.1 - 3.1e-20 73.1 0.0 5.7e-12 46.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM84831.1 - 7.6e-14 50.7 0.0 7.6e-07 27.7 0.0 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIM84831.1 - 1.1e-11 45.0 0.0 0.00017 21.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM84831.1 - 1.7e-09 37.5 0.6 3.9e-08 33.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM84831.1 - 6.1e-06 26.5 0.8 0.14 12.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM84831.1 - 1.3e-05 24.3 0.5 0.00011 21.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIM84831.1 - 1.4e-05 24.2 0.1 0.00061 18.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EIM84831.1 - 0.00018 20.6 0.6 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family PA PF02225.17 EIM84831.1 - 0.0017 18.0 0.1 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 PA domain NAD_binding_9 PF13454.1 EIM84831.1 - 0.0019 18.0 0.2 0.06 13.1 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIM84831.1 - 0.0021 17.7 1.4 0.0052 16.4 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EIM84831.1 - 0.0042 16.2 0.0 0.032 13.3 0.0 2.1 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIM84831.1 - 0.0053 15.2 2.2 0.42 9.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EIM84831.1 - 0.0057 16.2 0.3 0.077 12.5 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EIM84831.1 - 0.0081 15.0 3.3 0.16 10.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIM84831.1 - 0.01 14.7 1.9 2.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIM84831.1 - 0.011 14.8 0.1 0.33 9.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1405 PF07187.6 EIM84831.1 - 0.028 14.1 0.2 0.1 12.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1405) 2-Hacid_dh_C PF02826.14 EIM84831.1 - 0.028 13.5 0.1 0.4 9.8 0.0 2.5 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIM84831.1 - 0.033 14.4 0.4 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIM84831.1 - 0.043 13.9 0.1 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Piwi PF02171.12 EIM84832.1 - 4.5e-75 252.4 0.0 6e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIM84832.1 - 3.6e-17 61.9 0.0 6.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIM84832.1 - 1.6e-09 37.0 0.0 8.2e-09 34.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PSI_PsaE PF02427.12 EIM84832.1 - 0.026 13.9 0.0 11 5.4 0.0 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE p450 PF00067.17 EIM84833.1 - 5e-65 219.8 0.0 6.2e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EOS1 PF12326.3 EIM84834.1 - 3.6e-14 52.6 3.9 6.1e-14 51.9 2.7 1.4 1 0 0 1 1 1 1 N-glycosylation protein TMEM171 PF15471.1 EIM84834.1 - 2.3 6.9 9.3 1 8.1 3.4 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 ABM PF03992.11 EIM84835.1 - 1.1e-07 31.7 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Epimerase PF01370.16 EIM84838.1 - 1.3e-18 67.3 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM84838.1 - 5.7e-14 51.4 0.0 1.1e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM84838.1 - 3.3e-13 50.0 0.2 1.8e-12 47.6 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM84838.1 - 2e-07 30.2 0.0 1.4e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM84838.1 - 0.00019 20.7 0.1 0.0033 16.6 0.2 2.2 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EIM84838.1 - 0.0066 15.3 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM84838.1 - 0.011 15.6 0.4 0.077 12.9 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Aldo_ket_red PF00248.16 EIM84840.1 - 1.3e-71 240.6 0.0 1.5e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Yae1_N PF09811.4 EIM84841.1 - 2.8e-10 39.5 2.6 4.7e-10 38.8 1.8 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.17 EIM84842.1 - 1.6e-05 25.0 0.0 0.00042 20.4 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain DUF3638 PF12340.3 EIM84843.1 - 7.7e-85 283.5 0.4 1.7e-84 282.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIM84843.1 - 6.2e-18 63.6 0.1 1.3e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Proteasome PF00227.21 EIM84843.1 - 3.8 6.7 2.4 3.4 6.9 0.0 2.1 3 0 0 3 3 3 0 Proteasome subunit Cu_amine_oxid PF01179.15 EIM84844.1 - 7.1e-152 505.8 0.0 1.1e-151 505.2 0.0 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EIM84844.1 - 1.8e-13 50.3 0.0 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EIM84844.1 - 3.2e-05 23.9 0.1 8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Tom5 PF10642.4 EIM84844.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Glyco_hydro_18 PF00704.23 EIM84845.1 - 1.9e-11 44.0 0.3 2.3e-11 43.7 0.2 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Rad60-SLD PF11976.3 EIM84846.1 - 1.8e-07 30.7 0.1 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIM84846.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family TUG-UBL1 PF11470.3 EIM84846.1 - 0.062 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Rad60-SLD PF11976.3 EIM84847.1 - 2e-12 46.6 0.0 2.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIM84847.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Alba PF01918.16 EIM84847.1 - 0.029 13.9 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Alba PB1 PF00564.19 EIM84847.1 - 0.076 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PB1 domain TUG-UBL1 PF11470.3 EIM84847.1 - 0.088 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Methyltransf_16 PF10294.4 EIM84848.1 - 5.1e-29 100.9 0.0 1.5e-28 99.4 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EIM84848.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM84848.1 - 0.0025 17.3 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM84848.1 - 0.0085 16.6 0.0 0.021 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EIM84848.1 - 0.029 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 EIM84848.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cobalamin_bind PF01122.14 EIM84848.1 - 0.077 11.5 0.2 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein FAD_binding_3 PF01494.14 EIM84849.1 - 2.1e-94 316.4 0.1 2.7e-94 316.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM84849.1 - 3.3e-19 69.1 0.0 9.3e-19 67.6 0.0 1.8 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EIM84849.1 - 4.1e-07 28.8 1.1 6e-07 28.2 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIM84849.1 - 1.9e-06 27.8 0.0 1.3e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM84849.1 - 1e-05 25.8 0.2 0.00017 21.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM84849.1 - 6.6e-05 22.1 0.1 0.00013 21.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIM84849.1 - 0.00013 21.0 0.8 0.00078 18.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM84849.1 - 0.00017 21.5 0.1 0.00046 20.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM84849.1 - 0.00019 20.4 0.3 0.00037 19.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIM84849.1 - 0.00051 19.0 0.6 0.00091 18.2 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EIM84849.1 - 0.00083 18.3 0.4 0.0016 17.3 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIM84849.1 - 0.00086 18.4 0.1 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EIM84849.1 - 0.001 18.7 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2199 PF09965.4 EIM84849.1 - 0.0016 18.3 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2199) Pyr_redox_3 PF13738.1 EIM84849.1 - 0.0038 17.3 0.8 0.01 15.9 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIM84849.1 - 0.0047 16.9 0.1 0.013 15.5 0.1 1.7 2 0 0 2 2 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EIM84849.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EIM84849.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 EIM84849.1 - 0.027 13.3 0.0 0.13 11.0 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.1 EIM84849.1 - 0.078 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 EIM84849.1 - 0.095 12.5 0.2 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 EIM84849.1 - 0.14 12.4 0.1 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding SIC PF03482.8 EIM84850.1 - 0.019 14.6 4.0 0.016 14.8 2.4 1.3 1 1 0 1 1 1 0 sic protein TFIIS_M PF07500.9 EIM84851.1 - 1.6e-33 115.1 0.2 1.6e-33 115.1 0.2 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EIM84851.1 - 6.7e-17 60.8 11.0 1.1e-16 60.1 7.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EIM84851.1 - 7.8e-13 47.7 0.7 7.8e-13 47.7 0.5 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Pec_lyase_C PF00544.14 EIM84852.1 - 2.9e-16 59.5 8.6 6e-16 58.5 6.0 1.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EIM84852.1 - 3.1e-07 30.2 17.0 3.8e-07 29.9 9.9 2.1 1 1 1 2 2 2 2 Right handed beta helix region DUF1793 PF08760.6 EIM84853.1 - 1.1e-19 70.9 0.0 2.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Ribonuc_L-PSP PF01042.16 EIM84853.1 - 0.035 13.8 0.5 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Endoribonuclease L-PSP Mito_carr PF00153.22 EIM84854.1 - 2e-22 78.6 9.0 3.5e-09 36.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EIM84855.1 - 2e-53 176.4 15.2 1.3e-08 34.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIM84855.1 - 0.00013 20.3 1.2 1.7 6.6 0.7 4.0 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Hydrolase_3 PF08282.7 EIM84856.1 - 1e-40 139.9 0.0 8.7e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIM84856.1 - 1.9e-08 33.9 0.1 0.0037 16.5 0.0 3.0 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EIM84856.1 - 1.2e-05 25.8 1.9 0.14 12.5 0.1 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM84856.1 - 0.0026 17.9 0.1 0.052 13.6 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAP PF03866.8 EIM84857.1 - 0.16 11.7 5.8 0.17 11.6 4.0 1.0 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) AJAP1_PANP_C PF15298.1 EIM84857.1 - 0.24 11.2 1.0 0.31 10.9 0.7 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus YrhK PF14145.1 EIM84857.1 - 0.92 9.2 4.6 2.4 7.8 3.2 1.8 1 1 0 1 1 1 0 YrhK-like protein Glycoprotein_B PF00606.13 EIM84857.1 - 1.2 7.0 3.5 1.3 6.9 2.4 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF2470 PF10615.4 EIM84858.1 - 9e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EIM84858.1 - 8.4e-06 25.6 2.6 1.2e-05 25.1 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) DUF3943 PF13084.1 EIM84858.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) SWI-SNF_Ssr4 PF08549.5 EIM84859.1 - 0.15 10.3 0.5 0.15 10.3 0.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GIDA PF01134.17 EIM84860.1 - 8.2e-140 466.0 0.0 3.3e-70 236.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EIM84860.1 - 5.9e-19 67.9 0.1 3.1e-18 65.6 0.0 2.2 3 0 0 3 3 3 1 GidA associated domain 3 FAD_oxidored PF12831.2 EIM84860.1 - 2e-08 33.7 0.5 3.3e-08 33.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM84860.1 - 4.1e-07 30.0 0.6 1.3e-06 28.4 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM84860.1 - 1.3e-05 24.2 0.6 0.018 13.9 0.3 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM84860.1 - 9e-05 21.4 1.0 0.0002 20.3 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM84860.1 - 0.00079 17.9 1.7 0.036 12.5 0.4 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EIM84860.1 - 0.003 17.9 0.2 0.01 16.2 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATG22 PF11700.3 EIM84861.1 - 5.2e-148 493.4 4.9 6e-148 493.2 3.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIM84861.1 - 2.5e-10 39.6 64.9 9.4e-06 24.5 13.1 4.0 3 1 2 5 5 5 3 Major Facilitator Superfamily Pec_lyase_C PF00544.14 EIM84862.1 - 9.9e-21 74.1 6.2 1.6e-20 73.4 4.3 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EIM84862.1 - 2.5e-07 30.5 16.0 2.5e-07 30.5 11.1 2.0 1 1 1 2 2 2 2 Right handed beta helix region AFT PF08731.6 EIM84864.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AFT PIP5K PF01504.13 EIM84865.1 - 1.2e-55 188.3 0.1 1.9e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase adh_short PF00106.20 EIM84866.1 - 5.6e-13 49.1 0.3 7.3e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84866.1 - 8.9e-05 22.3 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EIM84866.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIM84866.1 - 0.04 12.7 0.9 0.21 10.4 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EIM84866.1 - 0.051 13.6 0.0 0.098 12.7 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 EIM84867.1 - 1e-64 218.5 0.0 1.8e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM84867.1 - 2.6e-36 125.0 0.0 5.3e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM84867.1 - 6.2e-05 22.0 0.1 9.7e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM84867.1 - 0.0022 16.8 0.4 0.018 13.8 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM84867.1 - 0.0052 15.8 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EIM84867.1 - 0.019 14.8 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM84867.1 - 0.054 12.3 0.4 2.3 7.0 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM84867.1 - 0.13 10.6 1.1 0.21 10.0 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EIM84867.1 - 0.25 10.1 0.0 0.92 8.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_M56 PF05569.6 EIM84868.1 - 0.063 12.2 0.1 0.095 11.6 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 FimH_man-bind PF09160.5 EIM84868.1 - 0.087 12.6 0.2 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 FimH, mannose binding CBM_6 PF03422.10 EIM84868.1 - 0.58 10.3 4.7 0.1 12.7 0.3 2.0 2 1 0 2 2 2 0 Carbohydrate binding module (family 6) DAG1 PF05454.6 EIM84869.1 - 6e-05 22.3 0.2 8.8e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2975 PF11188.3 EIM84869.1 - 0.038 13.6 0.5 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) CBM_6 PF03422.10 EIM84869.1 - 0.13 12.3 4.0 1.3 9.1 0.1 2.9 2 2 0 2 2 2 0 Carbohydrate binding module (family 6) DUF202 PF02656.10 EIM84869.1 - 3.9 7.7 5.8 7.1 6.9 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Pro_isomerase PF00160.16 EIM84870.1 - 1.5e-47 161.6 0.2 1.7e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIM1 PF02966.11 EIM84871.1 - 6.9e-69 229.4 0.1 7.8e-69 229.3 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EIM84871.1 - 4.3e-05 23.1 0.1 5.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIM84871.1 - 0.015 15.4 0.4 0.023 14.7 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.10 EIM84871.1 - 0.015 15.0 0.3 0.028 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EIM84871.1 - 0.049 13.6 0.2 0.098 12.6 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin-like zf-CSL PF05207.8 EIM84872.1 - 5.1e-23 80.3 2.5 5.1e-23 80.3 1.7 1.9 2 0 0 2 2 1 1 CSL zinc finger Sporozoite_P67 PF05642.6 EIM84872.1 - 0.0069 14.3 4.1 0.0078 14.1 2.9 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SDA1 PF05285.7 EIM84872.1 - 0.021 14.1 9.6 0.02 14.2 6.7 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIM84872.1 - 0.057 11.3 11.2 0.058 11.3 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family zinc_ribbon_5 PF13719.1 EIM84872.1 - 0.099 12.2 1.8 0.18 11.4 1.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ebola_NP PF05505.7 EIM84872.1 - 0.13 10.3 3.8 0.14 10.2 2.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF506 PF04720.7 EIM84872.1 - 0.28 10.7 1.8 0.39 10.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) zinc_ribbon_4 PF13717.1 EIM84872.1 - 0.32 10.7 2.3 0.59 9.8 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Paf1 PF03985.8 EIM84872.1 - 0.34 9.5 9.4 0.44 9.2 6.5 1.1 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.1 EIM84872.1 - 0.56 9.8 5.3 1.2 8.7 3.8 1.5 1 1 0 1 1 1 0 FAM176 family Rep_4 PF05797.6 EIM84872.1 - 0.7 8.5 4.4 0.94 8.1 3.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) ATHILA PF03078.10 EIM84872.1 - 0.88 8.0 2.6 1 7.8 1.8 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family GAGA PF09237.6 EIM84872.1 - 0.91 9.1 3.0 0.75 9.4 0.9 1.8 2 1 0 2 2 2 0 GAGA factor Sigma70_ner PF04546.8 EIM84872.1 - 1.2 8.6 9.9 2 7.9 6.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region COPI_C PF06957.6 EIM84872.1 - 1.6 7.1 10.1 2.1 6.7 7.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus eIF-3c_N PF05470.7 EIM84872.1 - 1.7 6.6 8.6 2.1 6.3 6.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PI3K_1B_p101 PF10486.4 EIM84872.1 - 2.1 5.7 4.5 2.4 5.6 3.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CobT PF06213.7 EIM84872.1 - 3.6 6.6 15.2 4.4 6.3 10.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EIM84872.1 - 4 5.8 16.0 4.9 5.5 11.1 1.0 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EIM84872.1 - 4 5.6 12.8 5.2 5.3 8.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 EIM84872.1 - 4.1 6.5 11.3 4.8 6.3 7.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EIM84872.1 - 4.2 5.2 7.8 4.8 5.0 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EIM84872.1 - 5.3 5.1 8.3 6.2 4.9 5.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein F-box-like PF12937.2 EIM84875.1 - 6.2e-05 22.6 0.6 0.00012 21.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 EIM84876.1 - 5.3e-26 91.9 0.0 7.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM84876.1 - 5.1e-12 45.7 0.0 7.1e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM84876.1 - 2.1e-09 37.2 0.1 1.7e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIM84876.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EIM84876.1 - 0.00039 19.0 0.0 0.0066 14.9 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EIM84876.1 - 0.0096 15.1 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EIM84876.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_6 PF12697.2 EIM84877.1 - 5.5e-22 78.7 0.0 8.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM84877.1 - 5.1e-13 49.1 0.0 4.1e-12 46.1 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM84877.1 - 9.9e-13 48.0 0.0 3.1e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM84877.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative lysophospholipase DUF1057 PF06342.7 EIM84877.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ubiq_cyt_C_chap PF03981.7 EIM84878.1 - 3.2e-28 98.3 0.4 3.6e-13 49.5 0.0 3.1 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone ERp29 PF07749.7 EIM84878.1 - 0.14 12.8 0.2 0.92 10.1 0.2 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain CBFD_NFYB_HMF PF00808.18 EIM84879.1 - 1.3e-08 34.7 0.1 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APC_CDC26 PF10471.4 EIM84879.1 - 0.22 12.3 0.3 0.22 12.3 0.2 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 Daxx PF03344.10 EIM84879.1 - 0.44 8.9 11.2 0.74 8.2 7.8 1.3 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 EIM84879.1 - 4.6 5.3 10.1 5.4 5.1 7.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-MYND PF01753.13 EIM84880.1 - 1.8e-09 37.3 9.7 1.8e-09 37.3 6.8 2.7 2 1 1 3 3 3 1 MYND finger zf-ribbon_3 PF13248.1 EIM84880.1 - 0.069 12.3 3.9 0.16 11.1 2.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Helicase_C PF00271.26 EIM84881.1 - 5e-08 32.6 0.2 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRG PF05712.8 EIM84882.1 - 1.4e-46 157.9 0.0 6e-46 155.8 0.0 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 EIM84882.1 - 1.1e-08 34.6 0.1 1.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EIM84882.1 - 0.04 13.5 0.3 0.076 12.6 0.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.2 EIM84884.1 - 0.00026 20.6 0.4 0.00057 19.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Grp1_Fun34_YaaH PF01184.14 EIM84885.1 - 2.6e-25 88.9 18.9 3.6e-25 88.5 13.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family AA_permease_2 PF13520.1 EIM84886.1 - 7.7e-70 235.5 52.4 9.2e-70 235.3 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM84886.1 - 4.4e-17 61.5 46.7 5.9e-17 61.1 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EIM84886.1 - 1.1 8.7 12.6 0.14 11.7 3.3 2.8 1 1 1 2 2 2 0 Mediator of CRAC channel activity Amino_oxidase PF01593.19 EIM84887.1 - 1.2e-29 103.7 0.1 3.2e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIM84887.1 - 0.0064 16.4 0.0 0.035 14.1 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain F-box-like PF12937.2 EIM84889.1 - 0.019 14.6 0.1 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like AA_permease PF00324.16 EIM84891.1 - 0.23 9.7 5.0 0.31 9.3 2.6 1.7 2 0 0 2 2 2 0 Amino acid permease F-box-like PF12937.2 EIM84892.1 - 0.0016 18.1 0.1 0.0051 16.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM84892.1 - 0.019 14.6 1.0 0.2 11.3 0.1 2.6 2 0 0 2 2 2 0 F-box domain PsiF_repeat PF07769.9 EIM84892.1 - 0.24 10.9 0.0 0.58 9.7 0.0 1.6 1 0 0 1 1 1 0 psiF repeat Pkinase PF00069.20 EIM84893.1 - 3.3e-14 52.6 0.0 2.4e-12 46.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84893.1 - 0.00059 18.9 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MoCF_biosynth PF00994.19 EIM84894.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain G0-G1_switch_2 PF15103.1 EIM84894.1 - 0.12 12.6 0.0 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF3494 PF11999.3 EIM84895.1 - 2.3e-51 174.3 13.4 2.7e-51 174.1 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pectate_lyase_3 PF12708.2 EIM84895.1 - 0.017 15.2 0.2 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Pectate lyase superfamily protein zf-C2H2 PF00096.21 EIM84896.1 - 4.3e-08 33.0 12.0 7.2e-06 26.0 0.2 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM84896.1 - 6e-07 29.4 0.2 6e-07 29.4 0.1 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM84896.1 - 3.8e-05 23.7 8.2 0.00084 19.5 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIM84896.1 - 0.00089 19.0 3.3 0.83 9.6 0.1 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIM84896.1 - 0.1 12.8 0.2 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TAFII28 PF04719.9 EIM84897.1 - 1.7e-29 101.4 0.0 2.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 EIM84897.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ORC2 PF04084.9 EIM84898.1 - 1.6e-76 257.2 0.0 1.9e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ICMT PF04140.9 EIM84900.1 - 3.9e-13 49.4 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM84900.1 - 5.1e-12 45.8 2.4 1.4e-11 44.3 0.2 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM84900.1 - 3.8e-05 22.4 0.1 9.2e-05 21.1 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 EIM84900.1 - 0.0014 18.3 0.0 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIM84900.1 - 0.035 13.4 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PEMT PF04191.8 EIM84901.1 - 8.8e-14 51.5 0.6 1.5e-12 47.5 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIM84901.1 - 1e-12 48.0 0.0 3.1e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIM84901.1 - 0.0028 16.2 0.0 0.0082 14.7 0.0 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM84901.1 - 0.008 15.5 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIM84902.1 - 2.5e-13 50.0 0.1 3.8e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIM84902.1 - 7e-13 48.5 0.0 6.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIM84902.1 - 0.00058 18.5 0.0 0.0013 17.3 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIM84903.1 - 4.1e-13 49.3 0.4 3.7e-12 46.2 0.2 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIM84903.1 - 4.2e-13 49.3 0.1 2.8e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TctB PF07331.6 EIM84903.1 - 0.00015 21.4 1.0 0.0044 16.6 0.1 2.5 3 0 0 3 3 3 1 Tripartite tricarboxylate transporter TctB family ERG4_ERG24 PF01222.12 EIM84903.1 - 0.00041 19.0 0.0 0.0011 17.6 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM84903.1 - 0.061 12.6 0.1 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) adh_short PF00106.20 EIM84905.1 - 2.6e-21 76.2 0.0 4.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84905.1 - 1.5e-14 54.3 0.0 1.9e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EIM84905.1 - 1.5e-08 34.1 0.0 4.2e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 EIM84905.1 - 5.3e-05 22.9 0.0 0.00019 21.1 0.0 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EIM84905.1 - 0.00055 19.4 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIM84905.1 - 0.0022 17.0 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIM84905.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding SseC PF04888.7 EIM84906.1 - 0.27 10.5 7.0 0.3 10.3 4.8 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1700 PF08006.6 EIM84906.1 - 1 8.6 3.7 1.1 8.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Sld5 PF05916.6 EIM84907.1 - 5.4e-06 26.6 0.4 8.8e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein NAD_binding_4 PF07993.7 EIM84908.1 - 1.9e-31 108.8 0.0 4.4e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EIM84908.1 - 1.3e-30 106.2 0.0 3.4e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EIM84908.1 - 6.9e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM84908.1 - 0.0012 19.0 0.2 0.0035 17.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Lipid_DES PF08557.5 EIM84908.1 - 0.024 13.8 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) 3Beta_HSD PF01073.14 EIM84908.1 - 0.046 12.4 0.0 0.086 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3708 PF12501.3 EIM84908.1 - 0.11 12.3 0.6 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter adh_short PF00106.20 EIM84908.1 - 0.15 11.9 0.0 0.52 10.1 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EIM84909.1 - 1.9e-44 150.9 0.0 2.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM84909.1 - 2.8e-20 72.1 0.0 3.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM84909.1 - 6.9e-05 22.7 0.0 0.00017 21.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EIM84909.1 - 0.00084 18.9 0.0 0.099 12.1 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Peripla_BP_4 PF13407.1 EIM84909.1 - 0.015 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein domain Shikimate_DH PF01488.15 EIM84909.1 - 0.022 14.8 0.1 0.88 9.6 0.0 2.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_Phos_1 PF00300.17 EIM84911.1 - 2.8e-20 73.0 0.0 1.5e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_75 PF07335.6 EIM84913.1 - 8.8e-18 64.6 0.1 1.5e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Xan_ur_permease PF00860.15 EIM84914.1 - 3.4e-29 101.5 29.7 2.6e-28 98.6 20.6 2.2 1 1 0 1 1 1 1 Permease family NUFIP2 PF15293.1 EIM84915.1 - 0.037 12.7 0.2 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 DUF2848 PF11010.3 EIM84916.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) p450 PF00067.17 EIM84917.1 - 1.4e-61 208.4 0.0 1.8e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIM84918.1 - 6.3e-23 81.0 97.1 3.1e-17 62.3 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EIM84919.1 - 9.3e-52 176.0 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM84919.1 - 7.7e-05 21.7 0.1 0.00014 20.8 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM84919.1 - 8e-05 22.5 0.0 0.12 12.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM84919.1 - 0.00014 21.9 0.0 0.099 12.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM84919.1 - 0.00073 18.4 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A ThiF PF00899.16 EIM84919.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 EIM84919.1 - 0.003 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM84919.1 - 0.021 15.2 0.4 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM84919.1 - 0.028 14.2 0.2 0.69 9.6 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIM84919.1 - 0.034 13.2 0.1 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 EIM84919.1 - 0.066 12.3 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Shikimate_DH PF01488.15 EIM84919.1 - 0.081 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EIM84919.1 - 0.088 11.8 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIM84919.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Cys_Met_Meta_PP PF01053.15 EIM84920.1 - 8.2e-141 468.7 0.0 9.3e-141 468.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIM84920.1 - 3.4e-13 49.3 0.1 6.5e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIM84920.1 - 7.7e-11 41.5 0.1 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIM84920.1 - 9.9e-10 37.6 0.8 3.9e-09 35.7 0.5 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIM84920.1 - 3.6e-05 23.0 0.0 6.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EIM84920.1 - 5.5e-05 22.0 0.1 8.1e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EIM84920.1 - 0.00013 20.3 0.1 0.00018 19.9 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EIM84920.1 - 0.044 12.2 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF4361 PF14274.1 EIM84920.1 - 0.053 13.1 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) Epimerase PF01370.16 EIM84921.1 - 1.1e-22 80.6 0.0 3.3e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM84921.1 - 1.1e-19 70.2 0.0 1.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM84921.1 - 8.6e-18 64.9 0.5 1.4e-17 64.2 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM84921.1 - 2.3e-15 56.2 0.1 1.7e-13 50.1 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM84921.1 - 1.1e-08 34.6 0.3 2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EIM84921.1 - 2.6e-08 33.1 0.2 6.2e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM84921.1 - 5e-06 26.5 2.7 1.5e-05 24.9 1.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM84921.1 - 0.00026 19.9 0.1 0.062 12.1 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 EIM84921.1 - 0.043 12.7 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EIM84921.1 - 0.054 13.4 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EIM84921.1 - 0.14 12.5 0.8 0.62 10.3 0.1 2.1 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIM84921.1 - 0.14 11.7 2.3 0.78 9.3 1.6 2.0 1 1 0 1 1 1 0 KR domain FA_hydroxylase PF04116.8 EIM84922.1 - 7.3e-13 48.9 22.4 7.3e-13 48.9 15.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF89 PF01937.14 EIM84922.1 - 0.095 11.4 0.3 0.2 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF89 Lactamase_B_2 PF12706.2 EIM84923.1 - 3.6e-22 78.8 0.3 5.8e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIM84923.1 - 4.2e-14 52.5 3.8 4.2e-14 52.5 2.7 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM84923.1 - 0.0067 16.1 5.1 0.0067 16.1 3.5 2.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Abhydrolase_6 PF12697.2 EIM84924.1 - 5e-25 88.7 0.1 6.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM84924.1 - 1e-09 38.2 0.1 1.4e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM84924.1 - 1.5e-09 37.7 0.2 3.3e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIM84924.1 - 1.1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EIM84924.1 - 0.0095 14.4 0.1 0.034 12.6 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) p450 PF00067.17 EIM84926.1 - 5.1e-66 223.0 0.0 1.5e-65 221.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM84927.1 - 1.8e-68 231.1 0.1 1.3e-67 228.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF92 PF01940.11 EIM84929.1 - 1.8e-52 177.7 5.5 3.3e-52 176.8 3.8 1.4 1 1 0 1 1 1 1 Integral membrane protein DUF92 TraT PF05818.7 EIM84929.1 - 7.5 5.9 6.0 11 5.3 3.5 1.9 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Asp PF00026.18 EIM84930.1 - 1.8e-38 132.5 2.0 1.1e-20 74.1 3.6 3.5 2 2 0 2 2 2 2 Eukaryotic aspartyl protease zf-C2H2_4 PF13894.1 EIM84934.1 - 0.0037 17.4 15.9 0.03 14.6 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-HYPF PF07503.7 EIM84934.1 - 0.67 9.4 4.1 0.49 9.8 0.7 2.3 2 0 0 2 2 2 0 HypF finger EamA PF00892.15 EIM84935.1 - 1.4e-24 86.5 27.7 5.1e-15 55.6 5.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIM84935.1 - 4.4e-06 26.8 4.1 4.4e-06 26.8 2.8 3.7 2 2 0 4 4 4 2 Multidrug resistance efflux transporter DUF3433 PF11915.3 EIM84936.1 - 7.1e-19 67.7 4.2 2.4e-18 66.0 2.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) p450 PF00067.17 EIM84937.1 - 1.1e-66 225.2 0.0 3.4e-66 223.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Phage_GPO PF05929.6 EIM84937.1 - 0.47 9.6 2.4 0.71 9.0 1.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase adh_short PF00106.20 EIM84938.1 - 1.2e-22 80.5 0.1 1.7e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM84938.1 - 3.4e-09 36.6 0.0 5.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM84938.1 - 5e-08 33.0 0.1 1.6e-07 31.3 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM84938.1 - 0.0014 18.1 0.2 0.034 13.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SpoVAD PF07451.6 EIM84938.1 - 0.013 13.9 0.1 0.017 13.5 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) 3HCDH_N PF02737.13 EIM84938.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEM4 PF02602.10 EIM84938.1 - 0.092 11.9 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD DUF4243 PF14027.1 EIM84939.1 - 1.5e-71 241.5 0.0 1.8e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) UPF0172 PF03665.8 EIM84940.1 - 9.4e-43 145.9 0.0 1.1e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EIM84940.1 - 9.5e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease F-box-like PF12937.2 EIM84942.1 - 2.3e-05 24.0 0.3 2.3e-05 24.0 0.2 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIM84942.1 - 0.073 12.7 1.5 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 F-box domain TPR_14 PF13428.1 EIM84943.1 - 9.7e-13 47.5 18.7 0.0022 18.4 0.0 7.9 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM84943.1 - 3.8e-11 43.3 16.2 1.3e-05 25.7 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM84943.1 - 3e-10 39.5 9.6 0.00029 20.4 0.0 5.8 5 2 2 7 7 6 4 TPR repeat TPR_19 PF14559.1 EIM84943.1 - 9.4e-09 35.4 6.3 0.02 15.1 0.3 5.0 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM84943.1 - 5.9e-08 32.0 17.2 9.1e-05 22.0 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM84943.1 - 2.2e-05 24.3 7.9 0.24 11.3 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM84943.1 - 6.8e-05 22.9 0.8 5.4 7.2 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EIM84943.1 - 7.2e-05 22.2 8.9 0.00056 19.3 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM84943.1 - 0.0015 18.2 0.5 3.7 7.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM84943.1 - 0.0061 16.6 2.1 57 4.2 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIM84943.1 - 0.017 14.2 1.5 4.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM84943.1 - 0.03 14.0 0.1 4.6 7.2 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EIM84943.1 - 0.045 12.5 0.0 0.089 11.5 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EIM84943.1 - 0.54 10.8 10.3 84 3.9 0.0 6.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EIM84944.1 - 4.9e-22 77.7 0.0 9e-22 76.9 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase adh_short PF00106.20 EIM84945.1 - 5e-20 72.0 0.0 9.9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM84945.1 - 2.9e-07 30.5 0.0 5.3e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM84945.1 - 6.1e-06 26.0 0.3 1.3e-05 24.9 0.1 1.5 2 0 0 2 2 2 1 KR domain Na_Ca_ex PF01699.19 EIM84946.1 - 8.4e-15 54.6 18.7 4.6e-08 32.7 0.8 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Senescence_reg PF04520.8 EIM84948.1 - 0.17 12.3 9.6 0.33 11.4 6.7 1.4 1 0 0 1 1 1 0 Senescence regulator PhyH PF05721.8 EIM84949.1 - 5.6e-10 39.6 0.0 8.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2236 PF09995.4 EIM84950.1 - 2e-10 40.3 0.6 1e-09 38.0 0.4 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) p450 PF00067.17 EIM84951.1 - 2.2e-65 221.0 0.0 3.3e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.15 EIM84952.1 - 5.7e-16 58.5 0.2 1.9e-11 43.7 0.0 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain NodS PF05401.6 EIM84952.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) zf-C2H2 PF00096.21 EIM84952.1 - 0.27 11.6 13.5 1.5 9.2 2.4 3.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pyr_redox_2 PF07992.9 EIM84953.1 - 8.8e-20 71.4 0.0 5.1e-07 29.7 0.0 3.4 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM84953.1 - 7.4e-14 51.9 0.0 9.8e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM84953.1 - 1.6e-11 44.6 0.2 6.1e-06 26.4 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM84953.1 - 3.6e-09 35.9 0.0 6.1e-06 25.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIM84953.1 - 1.5e-07 30.7 0.2 0.052 12.4 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM84953.1 - 4.3e-05 22.1 0.0 0.33 9.3 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein TrkA_N PF02254.13 EIM84953.1 - 0.00043 20.2 0.0 0.07 13.1 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 EIM84953.1 - 0.00062 18.7 0.0 0.03 13.2 0.0 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein DHFR_1 PF00186.14 EIM84953.1 - 0.00096 18.7 0.1 0.73 9.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrofolate reductase NAD_binding_7 PF13241.1 EIM84953.1 - 0.0013 18.9 0.1 0.32 11.2 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIM84953.1 - 0.005 16.6 0.3 0.52 10.0 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding Glyco_tran_28_C PF04101.11 EIM84953.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AMP-binding PF00501.23 EIM84954.1 - 7.3e-36 123.4 0.0 1.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM84954.1 - 4.5e-28 97.8 0.0 1.2e-27 96.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIM84954.1 - 0.00012 21.5 0.0 0.00027 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM84954.1 - 0.0014 17.4 0.0 0.12 11.0 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIM84954.1 - 0.24 11.3 0.2 1.6 8.6 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase AMP-binding PF00501.23 EIM84955.1 - 4.3e-32 111.0 0.0 6.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM84955.1 - 1.7e-30 105.7 0.0 5.2e-30 104.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIM84955.1 - 0.00014 21.4 0.0 0.00052 19.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM84955.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIM84955.1 - 0.22 10.1 0.0 0.59 8.7 0.0 1.7 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.9 EIM84956.1 - 2.7e-14 53.5 0.0 1.5e-13 51.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM84956.1 - 8.8e-13 48.4 0.1 1.5e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM84956.1 - 1.1e-06 28.9 0.0 0.03 14.3 0.0 3.6 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM84956.1 - 1.3e-05 24.3 0.0 0.082 11.8 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIM84956.1 - 0.00041 19.3 0.0 0.0055 15.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIM84956.1 - 0.0007 19.5 0.0 0.85 9.6 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM84956.1 - 0.0047 15.6 0.1 0.32 9.5 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIM84956.1 - 0.0066 15.4 0.0 0.13 11.1 0.0 2.4 2 1 1 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM84956.1 - 0.024 13.1 0.0 4.4 5.6 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EIM84956.1 - 0.049 13.8 0.1 9.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIM84956.1 - 0.096 12.6 0.1 3 7.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain PI-PLC-X PF00388.14 EIM84957.1 - 1.2e-42 144.7 0.0 2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EIM84957.1 - 2.1e-27 95.4 0.0 3.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EIM84957.1 - 0.15 11.9 1.8 0.38 10.6 0.5 2.3 2 1 0 2 2 2 0 C2 domain SIT PF15330.1 EIM84958.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Mito_fiss_reg PF05308.6 EIM84958.1 - 4.7 6.4 12.5 0.037 13.4 2.4 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator CPSase_L_D2 PF02786.12 EIM84959.1 - 1e-113 377.8 0.2 1.8e-81 272.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EIM84959.1 - 9.3e-46 154.5 0.0 2.5e-45 153.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIM84959.1 - 6.2e-45 153.0 0.0 2.9e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EIM84959.1 - 1.1e-43 148.3 0.0 2.2e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EIM84959.1 - 1.2e-42 144.5 0.1 2.6e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EIM84959.1 - 1.1e-40 138.0 0.0 3e-19 69.1 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EIM84959.1 - 3.8e-36 124.3 0.0 1e-35 122.9 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EIM84959.1 - 3.2e-35 121.5 0.1 9.4e-23 80.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIM84959.1 - 4.9e-23 81.3 0.0 1.3e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EIM84959.1 - 7.5e-20 70.6 0.0 3.1e-19 68.6 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EIM84959.1 - 1.7e-15 56.9 0.2 1.7e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIM84959.1 - 1.5e-14 53.7 0.1 6.4e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EIM84959.1 - 7.6e-06 25.8 0.3 0.0088 15.9 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EIM84959.1 - 7.6e-05 22.2 0.2 0.0022 17.4 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 Glyco_hydro_3_C PF01915.17 EIM84960.1 - 4.4e-49 167.0 0.0 3e-48 164.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EIM84960.1 - 4.5e-49 167.0 0.0 7e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EIM84960.1 - 8.2e-16 57.7 0.1 1.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIM84960.1 - 1.1e-07 31.6 0.5 5.4e-07 29.3 0.1 2.3 2 0 0 2 2 2 1 PA14 domain Glyco_hydro_53 PF07745.8 EIM84961.1 - 1.8e-84 283.3 0.0 2.1e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Tubulin PF00091.20 EIM84962.1 - 7.3e-68 228.6 0.0 1.3e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIM84962.1 - 1.9e-49 166.8 0.1 3.1e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIM84962.1 - 1.5e-05 24.9 0.0 4.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIM84962.1 - 0.024 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Hydrophobin_2 PF06766.6 EIM84963.1 - 0.34 10.6 4.4 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Fungal hydrophobin Glyco_trans_2_3 PF13632.1 EIM84964.1 - 1.7e-52 177.9 0.2 1.7e-52 177.9 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM84964.1 - 2.4e-10 40.6 0.0 4.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIM84964.1 - 0.0016 18.1 0.0 0.0071 16.0 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM84964.1 - 0.14 11.4 0.0 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 EIM84966.1 - 1e-24 86.8 0.3 2.3e-24 85.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Prefoldin PF02996.12 EIM84967.1 - 1.5e-27 95.6 2.2 1.8e-27 95.3 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIM84967.1 - 1.4e-05 24.7 0.1 2.4e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 EIM84967.1 - 0.0013 18.9 2.6 0.16 12.0 0.2 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EIM84967.1 - 0.0043 16.7 1.2 0.32 10.7 0.1 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 EIM84967.1 - 0.018 14.8 4.6 0.056 13.2 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EIM84967.1 - 0.026 14.3 2.1 1.6 8.5 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC PF05010.9 EIM84967.1 - 0.053 13.2 3.0 0.14 11.8 2.1 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) XkdW PF09636.5 EIM84967.1 - 0.061 13.1 0.3 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 XkdW protein Spore_SspJ PF09575.5 EIM84967.1 - 0.066 13.4 0.2 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Atg14 PF10186.4 EIM84967.1 - 0.077 11.9 1.4 2.1 7.2 0.1 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EIM84967.1 - 0.08 12.7 3.5 1.9 8.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.1 EIM84967.1 - 0.092 12.8 1.3 6.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Bacillus_HBL PF05791.6 EIM84967.1 - 0.094 12.0 4.1 2.8 7.2 0.3 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3209 PF11483.3 EIM84967.1 - 0.11 12.8 0.1 1.6 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) HR1 PF02185.11 EIM84967.1 - 0.11 12.1 3.3 1.2 8.8 0.2 2.4 2 1 0 2 2 2 0 Hr1 repeat V-SNARE PF05008.10 EIM84967.1 - 0.12 12.5 3.7 2.9 8.1 0.1 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.7 EIM84967.1 - 0.19 12.1 4.3 2 8.8 0.2 2.3 2 0 0 2 2 2 0 SlyX COG2 PF06148.6 EIM84967.1 - 0.19 11.5 3.4 3.6 7.4 0.1 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_1 PF00170.16 EIM84967.1 - 0.22 11.4 2.7 9.8 6.2 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 EIM84967.1 - 0.28 11.0 2.7 7.4 6.4 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EIM84967.1 - 0.34 10.9 4.5 5.1 7.1 0.3 2.1 2 0 0 2 2 2 0 DivIVA protein NPV_P10 PF05531.7 EIM84967.1 - 0.35 11.1 4.0 1.2 9.4 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tektin PF03148.9 EIM84967.1 - 0.35 9.3 3.3 6.5 5.1 0.2 2.0 2 0 0 2 2 2 0 Tektin family Tropomyosin_1 PF12718.2 EIM84967.1 - 0.49 10.2 4.0 0.92 9.3 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 EIM84967.1 - 0.82 9.5 6.1 2.4 8.0 0.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EIM84967.1 - 2.2 7.8 4.9 21 4.6 3.4 2.0 1 1 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EIM84967.1 - 3.9 6.6 6.7 1.3 8.2 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) MAGE PF01454.14 EIM84968.1 - 2.1e-37 128.3 0.3 2.5e-33 115.0 0.0 2.2 2 0 0 2 2 2 2 MAGE family PBP1_TM PF14812.1 EIM84968.1 - 2.4 8.5 24.4 0.95 9.8 2.3 3.8 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIN_4 PF13638.1 EIM84971.1 - 2.4e-07 30.9 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain DUF2347 PF09804.4 EIM84972.1 - 1.2e-52 178.9 0.0 8.5e-39 133.5 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EIM84972.1 - 7.2e-07 28.0 0.0 0.014 13.8 0.0 2.9 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EIM84972.1 - 9.2e-05 22.1 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis DUF4484 PF14831.1 EIM84972.1 - 0.0081 16.2 0.0 0.061 13.4 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) Lactamase_B_2 PF12706.2 EIM84973.1 - 1e-05 25.1 1.7 1.7e-05 24.4 1.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM84973.1 - 1e-05 25.2 4.0 1e-05 25.2 2.8 1.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily SAC3_GANP PF03399.11 EIM84974.1 - 7.4e-21 74.6 0.3 1.1e-20 74.0 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WSC PF01822.14 EIM84975.1 - 3e-69 228.9 51.1 8.6e-19 67.2 9.1 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EIM84975.1 - 7.3e-27 93.9 0.0 1.6e-23 83.0 0.0 3.4 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM84975.1 - 4.6e-23 81.1 0.3 1e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM84975.1 - 0.00047 19.8 0.1 0.94 9.2 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 EIM84975.1 - 0.091 12.5 3.1 33 4.4 0.0 4.9 6 0 0 6 6 6 0 Kelch motif Gti1_Pac2 PF09729.4 EIM84976.1 - 5.2e-57 192.3 0.0 6.4e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family A_deaminase PF00962.17 EIM84977.1 - 1.4e-49 168.8 0.0 2.4e-49 168.0 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EIM84977.1 - 2.2e-05 24.4 0.0 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal DUF2046 PF09755.4 EIM84977.1 - 0.14 11.0 0.7 0.26 10.1 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) AMP-binding PF00501.23 EIM84978.1 - 2.4e-33 115.1 0.0 5.5e-33 113.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM84978.1 - 1.2e-28 99.6 0.0 2.6e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIM84978.1 - 1.7e-06 27.6 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM84978.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIM84978.1 - 0.044 12.4 0.0 0.094 11.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EIM84978.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Hydrophobin PF01185.13 EIM84981.1 - 0.02 15.3 1.6 0.039 14.4 1.1 1.5 1 1 0 1 1 1 0 Fungal hydrophobin CybS PF05328.7 EIM84982.1 - 2.1e-47 160.0 0.1 2.3e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 CybS DJ-1_PfpI PF01965.19 EIM84983.1 - 6.1e-07 29.0 0.0 3.4e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIM84983.1 - 0.0039 16.4 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EIM84983.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain FHA PF00498.21 EIM84984.1 - 1.5e-09 37.7 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.7 EIM84984.1 - 2.4e-05 24.1 6.8 0.00021 21.0 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EIM84984.1 - 0.0075 16.0 2.0 0.0075 16.0 1.4 2.4 2 0 0 2 2 2 1 Laminin Domain II DUF3450 PF11932.3 EIM84984.1 - 0.042 13.1 7.7 0.015 14.5 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_13 PF13166.1 EIM84984.1 - 0.046 12.1 3.2 0.064 11.7 2.2 1.2 1 0 0 1 1 1 0 AAA domain DUF3322 PF11795.3 EIM84984.1 - 0.052 13.1 4.1 0.12 12.0 2.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) IncA PF04156.9 EIM84984.1 - 0.24 10.9 17.1 1.9 8.0 11.9 2.2 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EIM84984.1 - 0.26 11.7 17.4 0.27 11.6 0.8 3.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.16 EIM84984.1 - 0.3 11.3 9.7 1.4 9.2 1.8 2.9 2 1 0 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.7 EIM84984.1 - 0.57 9.9 15.4 0.05 13.3 3.7 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EIM84984.1 - 0.79 7.4 6.7 0.7 7.6 3.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EIM84984.1 - 1.2 8.9 4.5 3.2 7.5 0.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EIM84984.1 - 2.1 7.3 13.3 2.6 6.9 2.9 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 EIM84984.1 - 3.8 6.8 5.9 4.7 6.5 1.3 2.5 2 0 0 2 2 2 0 fzo-like conserved region DUF972 PF06156.8 EIM84984.1 - 5.5 7.3 11.8 1 9.7 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EIM84984.1 - 8.3 5.4 14.2 1.7 7.7 2.2 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATP_bind_1 PF03029.12 EIM84985.1 - 6.7e-78 261.5 0.1 1.1e-77 260.7 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIM84985.1 - 5.6e-06 25.9 0.0 8e-05 22.1 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EIM84985.1 - 8.1e-05 22.1 0.4 0.00037 19.9 0.3 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 EIM84985.1 - 0.0011 17.8 0.9 0.077 11.6 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit AAA_33 PF13671.1 EIM84985.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIM84985.1 - 0.0024 17.8 0.0 0.0077 16.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EIM84985.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 EIM84985.1 - 0.0089 14.8 0.0 1.8 7.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EIM84985.1 - 0.01 16.6 1.0 0.028 15.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EIM84985.1 - 0.012 14.9 0.1 0.05 12.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 EIM84985.1 - 0.013 14.9 0.1 0.26 10.7 0.1 2.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EIM84985.1 - 0.019 14.0 0.1 0.053 12.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EIM84985.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EIM84985.1 - 0.031 13.7 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EIM84985.1 - 0.038 13.4 0.0 0.073 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 EIM84985.1 - 0.042 13.4 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIM84985.1 - 0.062 12.1 0.0 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EIM84985.1 - 0.07 12.8 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EIM84985.1 - 0.088 12.2 0.4 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EIM84985.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EIM84985.1 - 0.17 11.0 0.1 0.6 9.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 EIM84986.1 - 1.1e-75 254.1 0.0 1.3e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM84986.1 - 4.5e-34 117.7 0.0 5.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM84986.1 - 0.0056 15.6 0.0 0.24 10.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIM84986.1 - 0.0092 15.7 0.1 0.076 12.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIM84986.1 - 0.016 14.0 0.2 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 ABM PF03992.11 EIM84987.1 - 1.5e-07 31.3 0.1 1.8e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SKG6 PF08693.5 EIM84988.1 - 0.00069 18.8 4.1 0.00069 18.8 2.9 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Shisa PF13908.1 EIM84988.1 - 0.075 13.2 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Lamp PF01299.12 EIM84988.1 - 0.19 10.8 0.4 0.35 9.9 0.3 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Adeno_E3_CR2 PF02439.10 EIM84988.1 - 0.26 10.8 6.7 0.16 11.5 1.6 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF1049 PF06305.6 EIM84988.1 - 3.2 7.3 4.5 0.86 9.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1708 PF08101.6 EIM84989.1 - 2.1e-17 63.1 0.0 3.5e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) Pro_isomerase PF00160.16 EIM84990.1 - 7.8e-46 156.1 0.5 8.9e-46 155.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF262 PF03235.9 EIM84991.1 - 6.3e-17 62.2 0.4 2.6e-16 60.2 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function DUF262 SMC_N PF02463.14 EIM84992.1 - 1.8e-66 223.5 0.0 8.1e-66 221.3 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIM84992.1 - 1.3e-22 80.0 0.7 5.8e-22 77.9 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIM84992.1 - 2.8e-14 53.7 2.4 4.4e-06 26.8 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EIM84992.1 - 1.3e-12 48.5 14.7 1.3e-12 48.5 10.2 6.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EIM84992.1 - 3.2e-05 23.3 0.1 8.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIM84992.1 - 0.00014 21.0 0.1 0.00014 21.0 0.1 3.7 2 2 0 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 EIM84992.1 - 0.00083 18.6 21.0 0.0049 16.0 2.2 4.5 2 2 2 4 4 4 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 EIM84992.1 - 0.15 12.3 0.0 0.15 12.3 0.0 5.7 2 2 1 3 3 3 0 ABC transporter Peptidase_S32 PF05579.8 EIM84993.1 - 0.00051 19.1 0.1 0.00089 18.3 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S3 PF00944.14 EIM84993.1 - 0.0013 18.1 0.0 0.0035 16.7 0.0 1.7 2 0 0 2 2 2 1 Alphavirus core protein Trypsin_2 PF13365.1 EIM84993.1 - 0.0013 18.7 0.0 0.0085 16.0 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain PMM PF03332.8 EIM84993.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Peptidase_S46 PF10459.4 EIM84993.1 - 1 7.6 2.2 1.1 7.5 0.3 1.7 2 0 0 2 2 2 0 Peptidase S46 DIM PF08194.7 EIM84994.1 - 0.4 10.6 2.5 0.69 9.9 1.7 1.4 1 0 0 1 1 1 0 DIM protein Polysacc_deac_1 PF01522.16 EIM84995.1 - 1.2e-27 96.0 0.3 4.7e-27 94.0 0.0 2.2 3 0 0 3 3 3 1 Polysaccharide deacetylase PilX PF13681.1 EIM84995.1 - 0.36 11.3 5.7 3 8.3 0.3 3.1 3 0 0 3 3 3 0 Type IV pilus assembly protein PilX C-term Secretin_N_2 PF07655.8 EIM84995.1 - 0.62 10.4 10.8 5 7.5 0.0 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Inositol_P PF00459.20 EIM84996.1 - 3.1e-48 164.4 0.0 7.2e-48 163.2 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.17 EIM84997.1 - 1.9e-61 208.0 0.0 7.1e-61 206.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EIM84998.1 - 1.6e-48 160.9 17.7 3.3e-11 42.6 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EIM84998.1 - 1.7e-05 24.5 11.8 0.41 10.3 0.3 4.4 2 2 2 4 4 4 4 Transcription factor IIIC subunit delta N-term GTP_EFTU PF00009.22 EIM84999.1 - 3.9e-56 189.4 0.0 1.3e-55 187.7 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIM84999.1 - 3.1e-34 117.1 0.3 5.3e-33 113.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EIM84999.1 - 8.5e-29 99.2 0.0 1.8e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EIM84999.1 - 1.7e-22 79.0 0.0 4.3e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIM84999.1 - 6e-12 45.5 0.0 1.7e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 F-box-like PF12937.2 EIM85000.1 - 1.1e-10 41.1 0.9 2.2e-10 40.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM85000.1 - 0.0024 17.4 1.6 0.0028 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM85001.1 - 7.9e-15 54.3 0.2 1.4e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM85001.1 - 0.00012 21.5 0.4 0.0005 19.6 0.3 2.1 1 1 0 1 1 1 1 F-box domain LSR PF05624.9 EIM85002.1 - 0.21 11.3 0.5 0.31 10.7 0.3 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Rad10 PF03834.9 EIM85003.1 - 2e-26 91.4 0.1 2.9e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EIM85003.1 - 2.4e-09 37.2 0.0 4.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EIM85003.1 - 0.00079 19.2 0.0 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 EIM85003.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Peptidase_M48 PF01435.13 EIM85004.1 - 3.6e-28 98.6 0.0 7e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 EIM85004.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF3337 PF11816.3 EIM85005.1 - 1.7e-47 162.4 0.2 2e-46 158.9 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EIM85005.1 - 8.6e-32 107.8 23.4 5.5e-08 32.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIM85005.1 - 0.001 17.2 0.9 0.33 9.0 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 NAD_binding_9 PF13454.1 EIM85006.1 - 0.0017 18.1 0.0 0.013 15.2 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pkinase PF00069.20 EIM85009.1 - 9.8e-10 38.0 0.0 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85009.1 - 0.018 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AChE_tetra PF08674.5 EIM85011.1 - 0.087 12.3 0.6 0.18 11.3 0.4 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Pkinase PF00069.20 EIM85012.1 - 3.5e-10 39.4 0.0 3.8e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85012.1 - 0.049 12.6 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EIM85013.1 - 4.8e-09 35.7 0.0 4e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85013.1 - 0.04 12.9 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase FMN_dh PF01070.13 EIM85014.1 - 4.3e-118 394.2 0.0 5.2e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIM85014.1 - 5.9e-21 74.0 0.0 1.8e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIM85014.1 - 6.8e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIM85014.1 - 0.001 18.0 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Phosphoprotein PF00922.12 EIM85016.1 - 0.0035 16.5 1.4 0.0054 15.9 1.0 1.3 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein DUF4064 PF13273.1 EIM85016.1 - 0.23 11.5 2.4 0.57 10.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF605 PF04652.11 EIM85017.1 - 1.6 8.0 13.5 2 7.7 9.4 1.1 1 0 0 1 1 1 0 Vta1 like Urb2 PF10441.4 EIM85018.1 - 0.078 12.5 2.5 0.093 12.3 1.7 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family DLIC PF05783.6 EIM85018.1 - 1.6 7.2 8.8 2 6.9 6.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Tim17 PF02466.14 EIM85019.1 - 6.4e-36 123.2 2.0 7.7e-36 122.9 1.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CcoS PF03597.10 EIM85019.1 - 0.097 12.1 0.2 7.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF543 PF04418.7 EIM85019.1 - 0.15 12.0 1.9 0.27 11.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF543) APH PF01636.18 EIM85020.1 - 3.1e-20 72.9 3.1 4e-20 72.5 2.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM85020.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIM85020.1 - 0.068 12.2 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIM85020.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EIM85020.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EIM85020.1 - 0.17 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RNase_PH PF01138.16 EIM85022.1 - 8.5e-20 71.4 0.0 1.5e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Cellulase PF00150.13 EIM85023.1 - 3.3e-31 108.5 0.1 5.3e-30 104.5 0.0 2.0 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF221 PF02714.10 EIM85025.1 - 1.7e-86 290.0 21.0 3.5e-86 289.0 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIM85025.1 - 6.2e-37 126.5 0.2 6.2e-37 126.5 0.1 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIM85025.1 - 3.9e-11 43.3 0.0 1.2e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RNA_pol_3_Rpc31 PF11705.3 EIM85026.1 - 0.0074 16.2 9.1 0.0092 15.9 6.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 EIM85026.1 - 0.036 13.7 7.0 0.044 13.4 4.8 1.2 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.6 EIM85026.1 - 0.039 13.7 14.6 0.071 12.9 10.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tim54 PF11711.3 EIM85026.1 - 0.043 12.4 4.2 0.05 12.1 2.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nucleoplasmin PF03066.10 EIM85026.1 - 0.046 13.2 14.9 0.06 12.8 10.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EIM85026.1 - 0.061 12.5 3.0 0.069 12.3 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein Ycf1 PF05758.7 EIM85026.1 - 0.11 10.2 5.7 0.11 10.1 3.9 1.0 1 0 0 1 1 1 0 Ycf1 Sigma70_ner PF04546.8 EIM85026.1 - 0.13 11.9 10.0 0.14 11.7 7.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Radial_spoke PF04712.7 EIM85026.1 - 0.13 10.9 16.2 0.16 10.6 11.2 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein RNA_polI_A34 PF08208.6 EIM85026.1 - 0.13 11.9 8.9 0.14 11.7 6.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RXT2_N PF08595.6 EIM85026.1 - 0.16 11.7 5.9 0.19 11.5 4.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal MIP-T3 PF10243.4 EIM85026.1 - 0.2 10.1 14.8 0.22 9.9 10.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BSP_II PF05432.6 EIM85026.1 - 0.23 10.6 23.0 0.29 10.3 16.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Daxx PF03344.10 EIM85026.1 - 0.25 9.7 15.9 0.26 9.7 11.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EIM85026.1 - 0.28 9.8 10.4 0.31 9.7 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FLO_LFY PF01698.11 EIM85026.1 - 0.34 9.7 6.5 0.39 9.5 4.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EIM85026.1 - 0.34 8.8 10.8 0.36 8.7 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EIM85026.1 - 0.35 11.1 13.9 0.49 10.7 9.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.7 EIM85026.1 - 0.48 8.7 15.9 0.62 8.3 11.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1266 PF06889.6 EIM85026.1 - 0.5 10.1 6.6 0.65 9.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF2890 PF11081.3 EIM85026.1 - 0.54 10.2 18.4 0.61 10.1 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Myc_N PF01056.13 EIM85026.1 - 0.62 9.1 13.6 0.81 8.7 9.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Zip PF02535.17 EIM85026.1 - 0.63 8.9 2.8 0.67 8.8 2.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.6 EIM85026.1 - 0.63 9.1 5.3 0.75 8.9 3.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.5 EIM85026.1 - 0.64 10.0 9.2 0.78 9.7 6.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 EIM85026.1 - 0.65 7.8 13.4 0.7 7.7 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 EIM85026.1 - 0.65 8.9 15.1 0.8 8.6 10.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.7 EIM85026.1 - 0.66 9.8 10.9 0.78 9.5 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GOLD_2 PF13897.1 EIM85026.1 - 0.69 10.1 7.3 0.88 9.7 5.1 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sporozoite_P67 PF05642.6 EIM85026.1 - 0.74 7.6 5.8 0.8 7.4 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mpp10 PF04006.7 EIM85026.1 - 0.79 8.0 15.6 0.93 7.7 10.8 1.0 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.7 EIM85026.1 - 1.2 8.2 12.1 1.2 8.1 8.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 EIM85026.1 - 1.2 8.6 10.8 1.4 8.4 7.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.8 EIM85026.1 - 1.3 7.7 16.7 1.4 7.5 11.5 1.0 1 0 0 1 1 1 0 Paf1 TLP-20 PF06088.6 EIM85026.1 - 1.4 8.5 4.5 1.6 8.3 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.6 EIM85026.1 - 1.4 8.2 13.1 1.7 7.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3381 PF11861.3 EIM85026.1 - 1.5 8.3 16.1 1.8 8.0 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CENP-B_dimeris PF09026.5 EIM85026.1 - 1.5 9.1 14.3 2.4 8.4 9.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EIM85026.1 - 1.5 6.9 14.4 1.6 6.8 10.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RNA_pol_Rpc4 PF05132.9 EIM85026.1 - 1.6 8.7 7.1 1.9 8.4 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3537 PF12056.3 EIM85026.1 - 1.7 7.2 3.8 2 7.0 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Prog_receptor PF02161.10 EIM85026.1 - 1.8 7.2 7.8 2 7.1 5.4 1.1 1 0 0 1 1 1 0 Progesterone receptor SRRM_C PF15230.1 EIM85026.1 - 2.7 8.1 10.4 4.1 7.5 7.1 1.4 1 1 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus YqfQ PF14181.1 EIM85026.1 - 2.8 7.9 9.6 3.3 7.7 6.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein AAR2 PF05282.6 EIM85026.1 - 3.1 6.6 6.9 3.9 6.3 4.8 1.0 1 0 0 1 1 1 0 AAR2 protein TRAP_alpha PF03896.11 EIM85026.1 - 3.1 6.6 10.6 3.7 6.4 7.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spore_coat_CotO PF14153.1 EIM85026.1 - 3.2 7.1 14.4 3.9 6.8 10.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Pox_RNA_Pol_19 PF05320.7 EIM85026.1 - 3.5 7.3 10.5 4.6 6.9 7.3 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BTV_NS2 PF04514.7 EIM85026.1 - 3.8 6.2 10.7 4.4 6.0 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDHD PF02862.12 EIM85026.1 - 3.9 7.1 7.2 4.6 6.9 5.0 1.1 1 0 0 1 1 1 0 DDHD domain IncA PF04156.9 EIM85026.1 - 4.1 6.9 6.9 4.6 6.7 4.8 1.1 1 0 0 1 1 1 0 IncA protein eIF-3c_N PF05470.7 EIM85026.1 - 4.9 5.1 8.9 5.8 4.8 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4366 PF14283.1 EIM85026.1 - 5.2 6.4 9.4 6.8 6.0 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3306 PF11748.3 EIM85026.1 - 6.2 7.5 14.1 8.4 7.0 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SAPS PF04499.10 EIM85026.1 - 8 4.9 6.6 9.1 4.7 4.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DAGK_cat PF00781.19 EIM85028.1 - 1.2e-19 69.9 0.0 2.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.3 EIM85028.1 - 0.2 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 2-Hacid_dh_C PF02826.14 EIM85029.1 - 4.4e-49 166.0 0.0 6.1e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM85029.1 - 1.5e-19 69.8 0.0 1.8e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM85029.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EIM85029.1 - 0.035 13.9 0.0 0.092 12.5 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RE_MjaI PF09568.5 EIM85029.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease Glyco_hydr_30_2 PF14587.1 EIM85030.1 - 3.7e-22 78.8 0.0 5.8e-19 68.2 0.0 2.2 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 DAO PF01266.19 EIM85031.1 - 4.7e-49 167.2 0.2 5.4e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM85031.1 - 9.8e-07 28.7 0.0 4.2e-06 26.6 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM85031.1 - 3.9e-05 23.8 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM85031.1 - 5.8e-05 23.1 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIM85031.1 - 0.00097 18.0 0.3 0.0035 16.2 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIM85031.1 - 0.0014 18.4 0.0 0.05 13.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM85031.1 - 0.0047 16.8 0.0 0.52 10.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM85031.1 - 0.005 15.7 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A ThiF PF00899.16 EIM85031.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 EIM85031.1 - 0.011 16.0 0.0 0.068 13.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85031.1 - 0.013 13.9 0.0 0.74 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 EIM85031.1 - 0.017 14.2 0.0 0.42 9.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIM85031.1 - 0.026 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Toprim_Crpt PF13342.1 EIM85031.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase GMC_oxred_N PF00732.14 EIM85031.1 - 0.029 13.5 0.0 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.12 EIM85031.1 - 0.032 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EIM85031.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EIM85031.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 1 0 short chain dehydrogenase NAD_binding_7 PF13241.1 EIM85031.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EIM85031.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EIM85032.1 - 2.5e-52 176.6 0.0 3.4e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM85032.1 - 1.7e-16 59.8 0.0 2.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM85032.1 - 2.3e-05 24.2 0.0 4.7e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EIM85032.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EIM85032.1 - 0.047 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1917 PF08939.5 EIM85033.1 - 2.9e-24 86.1 0.5 6.4e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) SUFU_C PF12470.3 EIM85033.1 - 0.38 10.3 5.6 0.41 10.2 0.0 2.4 2 1 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Lyase_aromatic PF00221.14 EIM85034.1 - 3.6e-157 523.6 2.6 4.7e-157 523.2 1.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 EIM85036.1 - 1.8e-28 99.5 0.6 2.7e-28 98.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM85036.1 - 4.3e-12 46.0 0.5 6.9e-12 45.3 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM85036.1 - 1.8e-10 40.9 0.3 2.5e-10 40.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM85036.1 - 7.9e-08 32.0 0.4 1.4e-07 31.2 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIM85036.1 - 7.7e-07 28.2 0.1 9e-07 28.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIM85036.1 - 0.0009 18.0 0.2 0.0013 17.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EIM85036.1 - 0.0018 18.0 0.3 0.0037 17.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EIM85036.1 - 0.0093 16.2 1.0 0.028 14.6 0.7 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EIM85036.1 - 0.13 12.2 4.4 0.36 10.8 3.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding ThiF PF00899.16 EIM85036.1 - 0.16 11.8 1.5 0.48 10.2 1.0 1.9 1 1 0 1 1 1 0 ThiF family Rer1 PF03248.8 EIM85038.1 - 1.5e-75 252.6 3.4 1.8e-75 252.4 2.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 EIM85038.1 - 0.034 13.3 3.4 0.056 12.6 2.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Rhabdo_glycop PF00974.13 EIM85038.1 - 0.083 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Arch_flagellin PF01917.11 EIM85039.1 - 0.14 11.7 0.4 0.18 11.3 0.3 1.1 1 0 0 1 1 1 0 Archaebacterial flagellin PsaM PF07465.8 EIM85039.1 - 0.42 10.2 3.0 0.82 9.3 2.1 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) SKG6 PF08693.5 EIM85040.1 - 0.0035 16.6 1.2 0.0081 15.4 0.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FixG_C PF11614.3 EIM85040.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase EphA2_TM PF14575.1 EIM85040.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EIM85040.1 - 0.26 10.9 1.2 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Syndecan domain AAA_16 PF13191.1 EIM85041.1 - 3e-06 27.3 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIM85041.1 - 0.00019 22.2 0.0 0.00044 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIM85041.1 - 0.0023 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Torsin PF06309.6 EIM85041.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_19 PF13245.1 EIM85041.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM85041.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIM85041.1 - 0.018 14.7 0.0 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EIM85041.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIM85041.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EIM85041.1 - 0.031 14.1 0.0 0.083 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EIM85041.1 - 0.037 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIM85041.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIM85041.1 - 0.067 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EIM85041.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIM85041.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIM85041.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EIM85041.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIM85041.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM85041.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIM85041.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EIM85041.1 - 0.15 11.0 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF4576 PF15144.1 EIM85042.1 - 0.014 14.9 0.1 0.063 12.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) zf-MYND PF01753.13 EIM85043.1 - 8.2e-11 41.6 11.8 1.2e-10 41.1 8.2 1.2 1 0 0 1 1 1 1 MYND finger Fcf1 PF04900.7 EIM85044.1 - 9.5e-39 131.5 0.4 9.5e-39 131.5 0.3 1.6 2 0 0 2 2 2 1 Fcf1 ARF7EP_C PF14949.1 EIM85044.1 - 0.23 11.9 2.2 0.95 9.9 0.0 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus RNase_T PF00929.19 EIM85049.1 - 1.1e-28 100.5 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Ank_4 PF13637.1 EIM85050.1 - 0.00013 22.3 1.5 3.7 8.1 0.0 5.2 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM85050.1 - 0.0095 16.2 0.0 0.32 11.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Dimer_Tnp_hAT PF05699.9 EIM85050.1 - 0.01 15.4 3.4 1.3 8.7 0.0 4.1 4 0 0 4 4 4 0 hAT family C-terminal dimerisation region Ank_5 PF13857.1 EIM85050.1 - 0.016 15.4 1.5 19 5.6 0.0 4.8 4 1 1 5 5 5 0 Ankyrin repeats (many copies) SWIB PF02201.13 EIM85051.1 - 3.9e-24 84.1 0.7 5.8e-24 83.5 0.5 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EIM85051.1 - 0.0031 17.2 0.1 0.011 15.5 0.1 1.9 1 1 0 1 1 1 1 DEK C terminal domain Sel1 PF08238.7 EIM85055.1 - 3.3e-29 100.6 47.3 2.1e-06 28.1 0.7 11.4 11 1 0 11 11 11 7 Sel1 repeat TPR_11 PF13414.1 EIM85055.1 - 1.3e-05 24.7 7.6 0.0034 16.9 0.3 4.3 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 EIM85055.1 - 0.1 12.5 3.9 4.1 7.3 0.1 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM85055.1 - 0.45 10.2 12.4 1.2 8.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM85055.1 - 1.2 9.9 0.0 1.2 9.9 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 EIM85056.1 - 2.5e-109 363.4 0.0 4.2e-83 277.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EIM85056.1 - 2.2e-39 134.0 0.1 4.2e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EIM85056.1 - 1.6e-36 125.8 0.2 2e-19 70.0 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EIM85056.1 - 6.5e-36 122.7 0.0 1.5e-18 66.8 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EIM85056.1 - 3.9e-21 75.1 0.0 1.3e-09 37.3 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIM85056.1 - 1.7e-16 60.0 0.0 8.1e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIM85056.1 - 8.4e-12 44.8 0.0 3.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EIM85056.1 - 8e-07 28.7 0.0 0.0048 16.3 0.0 2.8 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EIM85056.1 - 1.4e-05 24.4 0.0 0.045 12.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EIM85056.1 - 0.00014 21.8 0.0 0.076 12.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EIM85056.1 - 0.00056 19.7 0.0 0.014 15.3 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain GARS_A PF01071.14 EIM85056.1 - 0.048 13.2 0.1 0.69 9.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1456 PF07308.8 EIM85056.1 - 0.17 11.9 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) LRR_4 PF12799.2 EIM85057.1 - 0.56 9.8 2.8 44 3.8 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Hydantoinase_A PF01968.13 EIM85058.1 - 3.8e-84 282.2 0.8 3.8e-84 282.2 0.5 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EIM85058.1 - 6.5e-64 216.0 0.0 9.3e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EIM85058.1 - 5.8e-39 133.3 0.0 2.2e-36 125.0 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIM85058.1 - 6.7e-05 21.3 0.1 0.0043 15.4 0.1 2.3 2 0 0 2 2 2 2 MutL protein BRE1 PF08647.6 EIM85059.1 - 1.5 8.8 12.2 12 5.9 4.7 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SOG2 PF10428.4 EIM85059.1 - 4 5.9 8.5 6.4 5.3 5.9 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein NDUFA12 PF05071.11 EIM85060.1 - 0.0042 17.5 5.3 0.0045 17.4 0.1 2.2 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCCH_2 PF14608.1 EIM85064.1 - 0.0024 17.7 32.9 0.0059 16.5 3.5 4.1 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type Cyclin_N PF00134.18 EIM85065.1 - 5.4e-11 42.1 0.0 7.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIM85065.1 - 7e-09 36.2 0.9 1.6e-08 35.1 0.0 2.0 2 1 0 2 2 2 1 Cyclin Mitofilin PF09731.4 EIM85068.1 - 0.037 12.6 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_16 PF13191.1 EIM85068.1 - 0.058 13.3 0.1 0.24 11.3 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain DnaI_N PF07319.6 EIM85068.1 - 0.099 12.8 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Acetyltransf_1 PF00583.19 EIM85069.1 - 5.8e-05 23.0 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EIM85069.1 - 0.0015 18.6 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM85069.1 - 0.0033 17.3 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM85069.1 - 0.0035 17.3 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_dep_PLPC PF00882.13 EIM85069.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C Acetyltransf_1 PF00583.19 EIM85070.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIM85070.1 - 0.0036 17.1 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIM85070.1 - 0.037 14.2 0.1 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM85070.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NMO PF03060.10 EIM85071.1 - 8.2e-35 120.5 4.0 3.9e-34 118.2 2.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EIM85071.1 - 0.018 13.8 0.1 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PdxJ PF03740.8 EIM85071.1 - 0.11 11.6 0.5 0.35 9.9 0.1 1.8 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ DPBB_1 PF03330.13 EIM85072.1 - 3.5e-10 39.7 0.1 9.9e-10 38.2 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM85072.1 - 0.0026 17.4 0.3 0.0044 16.6 0.1 1.4 1 1 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.1 EIM85072.1 - 0.31 10.5 1.8 3.2 7.3 0.2 2.6 2 1 0 2 2 2 0 zinc-ribbon domain F-box-like PF12937.2 EIM85073.1 - 1.7e-07 30.8 0.0 5.5e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM85073.1 - 2.9e-06 26.7 0.0 2.9e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EIM85073.1 - 0.0031 17.2 5.3 6.4 6.6 0.0 4.9 5 1 0 5 5 5 2 Leucine rich repeat AMP-binding PF00501.23 EIM85074.1 - 3.7e-85 285.8 0.0 4.9e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM85074.1 - 9.9e-12 45.6 0.1 2.7e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NMO PF03060.10 EIM85075.1 - 1e-46 159.6 0.0 1.7e-46 158.9 0.0 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIM85075.1 - 7.2e-06 25.1 0.0 0.091 11.6 0.0 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EIM85075.1 - 0.014 14.3 0.5 0.023 13.6 0.3 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.13 EIM85075.1 - 0.02 13.7 0.9 0.02 13.7 0.6 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 EIM85075.1 - 0.084 12.1 0.4 0.76 8.9 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein MFS_1 PF07690.11 EIM85076.1 - 8.7e-29 100.3 18.7 1.4e-24 86.4 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 EIM85076.1 - 0.0006 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM85076.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EIM85076.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85076.1 - 0.026 14.3 0.1 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BcrAD_BadFG PF01869.15 EIM85077.1 - 3.2e-18 65.9 0.0 2.8e-09 36.6 0.0 2.7 1 1 1 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MFS_1 PF07690.11 EIM85079.1 - 0.00048 18.9 26.4 0.0044 15.7 5.8 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3733 PF12534.3 EIM85079.1 - 0.0041 16.3 0.4 0.011 15.0 0.3 1.7 1 0 0 1 1 1 1 Leucine-rich repeat containing protein 8 NfeD PF01957.13 EIM85079.1 - 0.011 15.8 2.6 0.036 14.1 0.0 2.6 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Sugar_tr PF00083.19 EIM85079.1 - 0.033 12.7 9.0 0.041 12.4 5.4 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter F-box-like PF12937.2 EIM85080.1 - 1e-07 31.5 0.2 2.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Cornichon PF03311.9 EIM85081.1 - 2.7e-53 179.4 8.8 3e-53 179.3 6.1 1.0 1 0 0 1 1 1 1 Cornichon protein FliS PF02561.9 EIM85081.1 - 0.073 12.9 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 Flagellar protein FliS DUF1634 PF07843.6 EIM85081.1 - 0.11 12.1 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) Oxidored_q3 PF00499.15 EIM85081.1 - 2.1 8.0 12.3 4.5 7.0 8.5 1.5 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF21 PF01595.15 EIM85081.1 - 7 5.9 8.5 1.5 8.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF21 Abhydrolase_3 PF07859.8 EIM85082.1 - 2.8e-47 161.0 0.0 4.8e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM85082.1 - 1e-11 44.2 0.0 2e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 EIM85082.1 - 0.004 16.6 0.4 2 7.7 0.0 2.3 2 0 0 2 2 2 2 Putative esterase Peptidase_S9 PF00326.16 EIM85082.1 - 0.034 13.3 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM85082.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.19 EIM85083.1 - 4.8e-47 160.5 0.0 5.6e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM85083.1 - 0.0013 18.8 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM85083.1 - 0.014 15.2 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM85083.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EIM85083.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EIM85083.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 KR domain NAD_binding_9 PF13454.1 EIM85083.1 - 0.14 11.8 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.16 EIM85083.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family DUF3678 PF12435.3 EIM85084.1 - 0.15 11.6 3.6 0.1 12.1 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) MFS_1 PF07690.11 EIM85085.1 - 8.2e-17 60.9 37.4 8.2e-17 60.9 25.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85085.1 - 2.6e-08 32.8 10.8 2.6e-08 32.8 7.5 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter UNC-93 PF05978.11 EIM85085.1 - 1.4e-07 31.1 3.0 1.4e-07 31.1 2.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 OATP PF03137.15 EIM85085.1 - 0.5 8.3 10.9 1.1 7.2 0.1 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family RNase_T PF00929.19 EIM85086.1 - 1e-22 81.2 0.0 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EIM85086.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease Period_C PF12114.3 EIM85086.1 - 0.25 10.9 3.8 0.51 9.9 2.7 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FtsJ PF01728.14 EIM85087.1 - 3.2e-14 53.3 0.0 7e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.14 EIM85088.1 - 7e-13 48.9 0.0 1.8e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.14 EIM85089.1 - 1.4e-17 64.2 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EIM85089.1 - 0.049 14.2 0.0 0.3 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain NAD_kinase PF01513.16 EIM85090.1 - 4.7e-61 206.0 0.0 5.8e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EIM85090.1 - 0.047 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain XPG_I_2 PF12813.2 EIM85092.1 - 6.4e-09 35.6 0.0 6.2e-08 32.4 0.0 2.4 3 0 0 3 3 3 1 XPG domain containing XPG_N PF00752.12 EIM85092.1 - 0.01 16.0 0.0 0.064 13.5 0.0 2.1 2 0 0 2 2 2 0 XPG N-terminal domain BRCT PF00533.21 EIM85094.1 - 0.001 19.2 0.0 0.0026 17.8 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CytochromB561_N PF09786.4 EIM85095.1 - 0.77 8.1 15.0 0.98 7.7 10.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal LCAT PF02450.10 EIM85096.1 - 6.4e-66 222.9 0.0 2.1e-65 221.2 0.0 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase CPDase PF07823.6 EIM85097.1 - 8.2e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein PARP PF00644.15 EIM85097.1 - 0.00057 19.3 0.0 0.0023 17.3 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EIM85098.1 - 5.4e-11 42.3 2.8 5.8e-08 32.3 0.1 2.6 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain DUF2116 PF09889.4 EIM85098.1 - 0.083 12.7 0.7 0.25 11.1 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-C4pol PF14260.1 EIM85098.1 - 0.11 12.5 4.5 0.29 11.1 0.7 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF329 PF03884.9 EIM85098.1 - 0.83 9.2 4.6 1.9 8.1 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) NAP PF00956.13 EIM85099.1 - 1.6e-42 145.3 0.0 1.6e-42 145.3 0.0 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ion_trans PF00520.26 EIM85100.1 - 1.2e-17 63.8 15.3 1.8e-17 63.2 10.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EIM85100.1 - 7.3e-13 48.0 4.8 7.3e-13 48.0 3.3 2.1 2 1 0 2 2 2 1 Ion channel Lig_chan PF00060.21 EIM85100.1 - 0.00066 19.4 0.6 0.0016 18.1 0.4 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel DUF962 PF06127.6 EIM85100.1 - 7.9 6.4 7.4 34 4.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Solute_trans_a PF03619.11 EIM85102.1 - 2e-75 253.6 15.6 2.4e-75 253.3 10.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3332 PF11810.3 EIM85102.1 - 0.15 11.7 0.4 0.24 11.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Pkinase PF00069.20 EIM85103.1 - 7.9e-72 241.5 0.0 9.6e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85103.1 - 2e-31 109.0 0.0 3.3e-31 108.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIM85103.1 - 0.015 14.9 0.1 0.047 13.4 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM85103.1 - 0.06 12.4 0.1 0.12 11.4 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAZ PF02170.17 EIM85103.1 - 0.11 11.8 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PAZ domain Tetraspannin PF00335.15 EIM85104.1 - 4.5e-05 22.8 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Tetraspanin family PH PF00169.24 EIM85106.1 - 5.9e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 PH domain FIST PF08495.5 EIM85106.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 FIST N domain PH_11 PF15413.1 EIM85106.1 - 0.23 11.7 0.1 0.53 10.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_M50 PF02163.17 EIM85107.1 - 0.0036 16.2 0.5 0.0053 15.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M50 UPF0233 PF06781.7 EIM85107.1 - 0.0076 15.8 0.6 0.0076 15.8 0.4 2.4 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0233) Trep_Strep PF09605.5 EIM85107.1 - 0.04 13.5 3.3 0.06 13.0 2.3 1.4 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ABC2_membrane_2 PF12679.2 EIM85107.1 - 0.042 12.7 7.7 0.061 12.1 5.3 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Prion PF00377.13 EIM85107.1 - 0.095 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain DUF4149 PF13664.1 EIM85107.1 - 0.85 9.7 6.8 2.9 8.0 3.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Aminotran_5 PF00266.14 EIM85108.1 - 2e-17 63.0 0.0 9e-17 60.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIM85108.1 - 0.00071 18.7 0.0 0.067 12.2 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIM85108.1 - 0.039 12.9 0.1 0.17 10.8 0.1 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II AvrL567-A PF11529.3 EIM85108.1 - 0.1 12.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A Plant_vir_prot PF01307.12 EIM85109.1 - 0.044 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Plant viral movement protein DUF4098 PF13345.1 EIM85109.1 - 0.052 13.4 6.4 0.13 12.2 0.3 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4098) zf-MYND PF01753.13 EIM85110.1 - 1.5e-08 34.3 10.4 1.5e-08 34.3 7.2 1.6 2 0 0 2 2 2 1 MYND finger Glyco_hydro_11 PF00457.12 EIM85110.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Pkinase PF00069.20 EIM85111.1 - 7e-30 104.0 0.0 9.8e-20 70.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85111.1 - 3.8e-17 62.2 0.1 2.3e-13 49.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIM85111.1 - 3.1e-05 23.8 0.0 0.0002 21.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM85111.1 - 0.0036 16.3 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM85111.1 - 0.0058 16.0 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIM85111.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acid_PPase PF12689.2 EIM85112.1 - 1e-60 204.2 0.0 1.1e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EIM85112.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EIM85112.1 - 0.0092 16.2 0.3 0.12 12.5 0.0 2.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_28 PF00295.12 EIM85113.1 - 3.6e-58 197.0 13.9 4.6e-58 196.7 9.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-MYND PF01753.13 EIM85114.1 - 1.7e-08 34.1 0.4 1.7e-08 34.1 0.3 1.6 2 0 0 2 2 2 1 MYND finger adh_short PF00106.20 EIM85115.1 - 8.9e-17 61.4 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM85115.1 - 3.5e-08 33.5 0.0 4.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM85115.1 - 0.00075 19.5 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM85115.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family OPT PF03169.10 EIM85116.1 - 6e-183 609.6 53.5 6.8e-183 609.4 37.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Patatin PF01734.17 EIM85117.1 - 2.4e-25 89.6 0.0 3.7e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase FAD_binding_3 PF01494.14 EIM85119.1 - 2e-22 79.7 0.0 3.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM85119.1 - 1e-08 34.5 0.9 0.00072 18.5 1.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM85119.1 - 3.9e-06 26.7 1.4 1.3e-05 25.0 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM85119.1 - 0.00024 20.0 10.1 0.001 18.0 5.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIM85119.1 - 0.0003 21.1 3.5 0.11 12.9 2.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM85119.1 - 0.00077 18.1 1.8 0.069 11.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EIM85119.1 - 0.0014 17.1 3.0 0.0092 14.4 2.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIM85119.1 - 0.0018 18.2 2.4 0.0044 16.9 1.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM85119.1 - 0.0055 15.8 1.0 0.011 14.9 0.7 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EIM85119.1 - 0.019 14.9 0.7 0.036 14.1 0.5 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM85119.1 - 0.028 13.4 1.2 5.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EIM85119.1 - 0.16 11.0 5.8 0.3 10.1 4.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM85119.1 - 0.3 9.9 1.9 14 4.4 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EIM85119.1 - 0.37 10.3 1.1 0.63 9.5 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EIM85119.1 - 0.98 8.2 6.8 1.5 7.5 4.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIM85119.1 - 1.5 8.4 3.5 2.6 7.6 2.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Evr1_Alr PF04777.8 EIM85120.1 - 1.3e-28 98.7 0.3 1.9e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family LSM PF01423.17 EIM85121.1 - 2.7e-15 55.6 0.1 3.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Amidase PF01425.16 EIM85123.1 - 2e-34 119.2 2.9 2e-34 119.2 2.0 2.0 3 0 0 3 3 3 1 Amidase Amidase PF01425.16 EIM85124.1 - 3.4e-34 118.4 1.9 3.4e-34 118.4 1.3 2.7 3 0 0 3 3 3 2 Amidase DUF4231 PF14015.1 EIM85125.1 - 0.36 10.8 7.4 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TMEM61 PF15105.1 EIM85125.1 - 5.5 6.4 8.3 0.43 10.0 1.8 2.0 2 0 0 2 2 2 0 TMEM61 protein family Claudin_2 PF13903.1 EIM85125.1 - 6.6 6.3 9.4 10 5.7 3.3 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MIF4G PF02854.14 EIM85126.1 - 1e-57 194.9 0.5 1.7e-57 194.2 0.4 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EIM85126.1 - 5.2e-19 67.8 0.0 1.8e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EIM85126.1 - 1e-08 34.8 0.1 5.1e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 MA3 domain LCM PF04072.9 EIM85127.1 - 4e-24 85.1 0.0 5.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TrkH PF02386.11 EIM85128.1 - 4.1e-48 163.7 6.1 8e-28 97.0 0.0 3.1 2 1 1 3 3 3 3 Cation transport protein Hum_adeno_E3A PF05393.6 EIM85128.1 - 0.011 15.3 4.2 0.79 9.4 0.2 3.6 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Vps54 PF07928.7 EIM85128.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Vps54-like protein TrkH PF02386.11 EIM85129.1 - 4.9e-21 74.6 0.0 6.6e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Cation transport protein TPT PF03151.11 EIM85130.1 - 8.5e-22 77.4 11.8 1.5e-18 66.8 2.1 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIM85130.1 - 7.5e-10 38.2 8.9 2.1e-07 30.1 1.4 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EIM85130.1 - 1.6e-07 31.4 25.5 6.7e-07 29.3 5.6 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIM85130.1 - 1.8e-05 24.8 1.9 1.8e-05 24.8 1.3 2.9 2 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF2648 PF10855.3 EIM85130.1 - 0.031 13.6 0.5 0.43 10.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) Nuc_sug_transp PF04142.10 EIM85130.1 - 0.34 9.9 6.6 0.29 10.1 0.2 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter Redoxin PF08534.5 EIM85131.1 - 2.7e-27 95.0 0.1 3.3e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIM85131.1 - 2.2e-15 56.4 0.0 2.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF824 PF05688.6 EIM85131.1 - 0.0039 16.7 0.2 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 Salmonella repeat of unknown function (DUF824) SNN_cytoplasm PF09051.5 EIM85131.1 - 0.005 16.5 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Stannin cytoplasmic Thioredoxin_8 PF13905.1 EIM85131.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Mid1 PF12929.2 EIM85132.1 - 2.2e-74 250.6 0.8 3e-74 250.2 0.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Cellulase PF00150.13 EIM85133.1 - 2e-31 109.2 1.4 3.3e-31 108.5 1.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF21 PF01595.15 EIM85136.1 - 3.4e-31 107.9 2.1 5.4e-31 107.2 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIM85136.1 - 0.0047 16.6 0.3 4.7 7.0 0.0 3.3 3 0 0 3 3 3 2 CBS domain ARD PF03079.9 EIM85137.1 - 3e-45 153.9 0.0 3.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EIM85137.1 - 5.2e-10 38.6 0.6 9.2e-10 37.8 0.0 1.7 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 EIM85137.1 - 1.8e-06 27.6 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIM85137.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIM85137.1 - 0.028 13.8 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Arrestin_C PF02752.17 EIM85139.1 - 3.7e-16 59.4 0.0 2.9e-14 53.3 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIM85139.1 - 5.9e-12 45.6 0.0 1.2e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Hex_IIIa PF02455.11 EIM85139.1 - 5.2 5.6 6.2 13 4.3 4.3 1.6 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ICMT PF04140.9 EIM85140.1 - 1.3e-14 54.1 0.8 1.8e-12 47.2 0.1 2.5 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM85140.1 - 1.7e-12 47.3 3.9 1.9e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM85140.1 - 1.9e-05 23.4 0.7 2.7e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Terminase_GpA PF05876.7 EIM85140.1 - 0.014 13.7 2.4 0.019 13.3 1.7 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Pkinase PF00069.20 EIM85144.1 - 5.6e-25 87.9 0.0 6.9e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85144.1 - 1.7e-08 33.8 0.0 2.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM85144.1 - 0.018 14.8 0.3 0.05 13.3 0.1 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribosomal_L14e PF01929.12 EIM85145.1 - 6.9e-26 90.4 0.1 9.6e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIM85145.1 - 6.5e-06 25.6 0.4 6.5e-06 25.6 0.3 1.7 2 0 0 2 2 2 1 KOW motif DUF2413 PF10310.4 EIM85147.1 - 0.3 9.8 2.6 0.29 9.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF2562 PF10814.3 EIM85147.1 - 1.5 8.8 11.1 0.32 10.9 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Ribosomal_S10 PF00338.17 EIM85148.1 - 2.3e-19 69.0 0.0 3.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Mago_nashi PF02792.9 EIM85149.1 - 1.8e-73 244.9 0.1 2.1e-73 244.7 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF4451 PF14616.1 EIM85150.1 - 1.7e-33 115.0 1.5 2e-33 114.7 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.19 EIM85151.1 - 1.7e-44 151.7 0.0 1.9e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA-synt_1 PF00133.17 EIM85152.1 - 1.1e-212 707.3 0.0 4.9e-212 705.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIM85152.1 - 1.8e-32 112.2 0.1 3.4e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIM85152.1 - 5.7e-17 61.4 0.0 5.2e-08 31.9 0.0 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIM85152.1 - 5.6e-11 42.0 0.1 4.1e-07 29.4 0.1 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EIM85152.1 - 0.0021 16.9 0.0 0.0059 15.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EIM85152.1 - 0.0079 15.3 0.0 0.22 10.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Cpn60_TCP1 PF00118.19 EIM85153.1 - 1.8e-117 392.9 4.4 2.1e-117 392.7 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EIM85153.1 - 0.94 9.1 4.6 0.43 10.2 0.4 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) NAD_binding_8 PF13450.1 EIM85154.1 - 9.2e-15 54.4 0.0 4.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM85154.1 - 1.2e-06 27.6 0.0 4.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM85154.1 - 2.7e-05 24.0 0.0 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EIM85154.1 - 4.8e-05 22.5 0.0 8.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIM85154.1 - 0.00012 21.0 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM85154.1 - 0.00037 20.6 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM85154.1 - 0.00047 20.1 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM85154.1 - 0.00062 20.1 0.0 0.061 13.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85154.1 - 0.0046 15.4 0.0 0.008 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIM85154.1 - 0.022 13.8 0.1 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIM85154.1 - 0.08 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EIM85154.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EIM85154.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SpoIIE PF07228.7 EIM85156.1 - 0.00019 21.1 0.0 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIM85156.1 - 0.0005 19.5 0.0 0.077 12.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIM85156.1 - 0.00069 19.0 0.1 0.006 16.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C BAR_2 PF10455.4 EIM85157.1 - 4.5e-48 163.6 2.3 1.7e-47 161.7 1.6 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EIM85157.1 - 3.3e-17 62.7 1.9 1.6e-16 60.5 1.3 1.8 1 1 0 1 1 1 1 BAR domain DALR_1 PF05746.10 EIM85157.1 - 0.008 16.1 5.4 0.013 15.4 0.5 2.4 1 1 1 2 2 2 1 DALR anticodon binding domain Phasin PF05597.6 EIM85157.1 - 0.011 15.4 1.4 0.028 14.1 0.0 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Uds1 PF15456.1 EIM85157.1 - 0.085 12.8 6.5 0.19 11.6 0.1 2.5 2 1 0 2 2 2 0 Up-regulated During Septation Proteasome PF00227.21 EIM85158.1 - 4e-48 163.2 0.2 5.1e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EIM85158.1 - 9.6e-12 43.9 0.5 2.1e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal CAP59_mtransfer PF11735.3 EIM85159.1 - 1.1e-48 165.5 0.0 1.9e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NMDAR2_C PF10565.4 EIM85159.1 - 0.065 11.9 0.2 0.098 11.3 0.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Dimer_Tnp_hAT PF05699.9 EIM85163.1 - 2.9e-06 26.8 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region YL1 PF05764.8 EIM85164.1 - 1.3 8.5 13.5 1.8 8.1 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 EIM85164.1 - 3.4 6.0 12.5 3.8 5.8 8.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EIM85164.1 - 5.8 4.8 12.6 7.1 4.5 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1030 PF06270.6 EIM85166.1 - 0.038 13.5 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Herpes_ORF11 PF04797.8 EIM85167.1 - 0.0079 14.6 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Asp_protease_2 PF13650.1 EIM85167.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.1 EIM85172.1 - 8.9e-21 74.1 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TetR_N PF00440.18 EIM85172.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family GerE PF00196.14 EIM85172.1 - 0.022 14.0 0.0 0.067 12.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EIM85172.1 - 0.038 13.4 0.1 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.11 EIM85172.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Adhesin_P1 PF03257.8 EIM85175.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma adhesin P1 Phage_integrase PF00589.17 EIM85176.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Phage integrase family UBN2_2 PF14227.1 EIM85177.1 - 2.2e-11 43.3 0.4 4.3e-11 42.4 0.3 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM85177.1 - 6e-08 32.4 0.5 4.1e-07 29.7 0.3 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Phg_2220_C PF09524.5 EIM85177.1 - 0.07 13.1 0.0 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) SAGA-Tad1 PF12767.2 EIM85180.1 - 0.078 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit EBV-NA3 PF05009.7 EIM85181.1 - 1.9 7.6 6.0 4.1 6.5 4.2 1.7 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF2890 PF11081.3 EIM85181.1 - 2.1 8.3 12.3 0.4 10.7 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Asp_protease PF09668.5 EIM85184.1 - 0.036 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease DUF1573 PF07610.6 EIM85184.1 - 0.13 11.8 0.2 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Glyco_hydro_61 PF03443.9 EIM85185.1 - 2.4e-44 151.7 0.0 3.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-Tim10_DDP PF02953.10 EIM85186.1 - 0.018 14.3 0.3 0.032 13.5 0.2 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Pkinase PF00069.20 EIM85188.1 - 7.2e-33 113.8 0.0 9e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85188.1 - 1.3e-13 50.6 0.0 2.6e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIM85188.1 - 0.006 16.3 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Flavin_Reduct PF01613.13 EIM85190.1 - 8.1e-24 84.2 0.1 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Med13_N PF11597.3 EIM85192.1 - 0.04 12.6 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Gamma-thionin PF00304.15 EIM85192.1 - 0.17 11.9 1.0 0.42 10.6 0.7 1.6 1 0 0 1 1 1 0 Gamma-thionin family OPT PF03169.10 EIM85193.1 - 1.1e-76 258.5 34.8 1.5e-76 258.1 24.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.14 EIM85194.1 - 1.4e-65 221.3 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM85194.1 - 7.5e-29 100.8 0.0 1.4e-27 96.7 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM85194.1 - 0.00021 21.2 0.6 0.0007 19.5 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM85194.1 - 0.00037 19.5 0.1 0.00055 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EIM85194.1 - 0.00068 18.6 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM85194.1 - 0.0015 17.5 0.0 0.053 12.3 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM85194.1 - 0.021 14.8 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIM85194.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EIM85194.1 - 0.055 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85194.1 - 0.11 10.9 0.1 0.21 10.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EIM85194.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Oxidored_FMN PF00724.15 EIM85195.1 - 2.3e-82 276.7 0.0 2.6e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.14 EIM85196.1 - 9.8e-14 51.1 0.0 1.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM85196.1 - 8e-08 32.2 0.0 2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM85196.1 - 1.2e-07 31.0 0.0 2.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM85196.1 - 3e-06 27.5 0.0 0.0036 17.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM85196.1 - 3.8e-05 22.7 0.0 6.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM85196.1 - 0.00024 20.2 0.1 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EIM85196.1 - 0.00073 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIM85196.1 - 0.0059 15.2 0.0 1.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EIM85196.1 - 0.0092 14.4 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIM85196.1 - 0.0095 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM85196.1 - 0.02 13.8 0.0 0.065 12.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM85196.1 - 0.031 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM85196.1 - 0.12 12.1 0.4 0.52 10.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding ICMT PF04140.9 EIM85197.1 - 9e-12 45.0 3.4 1.5e-11 44.3 0.4 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM85197.1 - 9.7e-09 35.2 2.2 2.6e-08 33.9 0.6 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM85197.1 - 0.00079 18.0 0.8 0.00079 18.0 0.5 1.6 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Pox_A14 PF05767.7 EIM85197.1 - 0.094 12.6 0.2 0.094 12.6 0.2 2.5 2 2 2 4 4 4 0 Poxvirus virion envelope protein A14 Acyl-CoA_dh_M PF02770.14 EIM85198.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain DUF829 PF05705.9 EIM85199.1 - 5.9e-33 114.5 0.0 7.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EIM85199.1 - 0.036 13.9 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HHH_5 PF14520.1 EIM85200.1 - 0.026 14.6 0.3 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain DEAD PF00270.24 EIM85201.1 - 5.9e-19 68.1 0.0 9.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM85201.1 - 1.6e-11 43.9 0.0 6.4e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM85201.1 - 0.051 13.3 0.5 0.27 11.0 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Vpu PF00558.14 EIM85201.1 - 0.09 12.3 0.2 0.09 12.3 0.1 2.8 3 0 0 3 3 3 0 Vpu protein DUF2229 PF09989.4 EIM85201.1 - 0.094 12.1 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF605 PF04652.11 EIM85201.1 - 1.1 8.5 28.7 0.055 12.8 2.1 2.2 2 0 0 2 2 2 0 Vta1 like Pkinase PF00069.20 EIM85202.1 - 1.2e-12 47.4 0.0 3.2e-11 42.8 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85202.1 - 0.0019 17.3 0.0 0.038 13.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ste5 PF11610.3 EIM85202.1 - 0.14 11.7 2.0 0.64 9.5 0.2 2.6 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region Herpes_gE PF02480.11 EIM85203.1 - 0.052 11.8 0.0 0.069 11.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4079 PF13301.1 EIM85203.1 - 0.39 10.6 5.3 21 5.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Mem_trans PF03547.13 EIM85203.1 - 5.5 5.1 7.4 1.6 6.9 2.0 1.9 2 0 0 2 2 2 0 Membrane transport protein Oxidored_FMN PF00724.15 EIM85205.1 - 4.8e-82 275.6 0.0 5.5e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4534 PF15049.1 EIM85206.1 - 0.066 12.8 3.4 0.43 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) 7tm_3 PF00003.17 EIM85206.1 - 0.11 11.8 3.5 0.22 10.8 2.4 1.5 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR dsrm PF00035.20 EIM85208.1 - 0.021 15.3 0.1 0.055 14.0 0.0 1.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif Trypan_PARP PF05887.6 EIM85208.1 - 0.047 13.4 0.0 0.047 13.4 0.0 2.2 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.17 EIM85210.1 - 5.4e-72 242.7 0.0 6.6e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_3 PF15421.1 EIM85210.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase MFS_1 PF07690.11 EIM85213.1 - 4.1e-35 121.1 30.0 5.7e-35 120.6 20.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85213.1 - 3.4e-08 32.4 21.9 6.3e-08 31.6 15.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Porphobil_deam PF01379.15 EIM85215.1 - 7.9e-17 60.8 0.3 7e-09 34.9 0.0 2.5 2 1 1 3 3 3 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EIM85215.1 - 6.6e-15 54.9 0.3 1.3e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Umbravirus_LDM PF04817.7 EIM85215.1 - 0.046 12.8 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family NAD_binding_4 PF07993.7 EIM85216.1 - 1.4e-07 30.7 0.0 2.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM85216.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EIM85217.1 - 1.7e-48 165.2 0.0 1e-47 162.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EIM85218.1 - 9.2e-19 67.6 10.6 1.3e-18 67.1 7.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EIM85219.1 - 2.4e-48 164.8 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM85220.1 - 1.5e-45 155.6 0.0 3e-45 154.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 EIM85221.1 - 8.9e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM85221.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM85221.1 - 0.00091 19.3 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM85221.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 EIM85221.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Caps_synth_CapC PF14102.1 EIM85223.1 - 0.27 11.3 3.7 0.15 12.2 0.9 1.8 1 1 1 2 2 2 0 Capsule biosynthesis CapC AA_permease PF00324.16 EIM85224.1 - 2.4e-110 369.1 43.1 2.8e-110 368.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM85224.1 - 4.1e-32 111.2 46.9 5.1e-32 110.9 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease ICMT PF04140.9 EIM85225.1 - 4.5e-12 46.0 0.3 6.8e-12 45.4 0.1 1.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM85225.1 - 1.5e-09 37.9 1.1 5.7e-08 32.8 0.2 2.0 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM85225.1 - 0.00011 20.8 0.0 0.00014 20.5 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FA_desaturase PF00487.19 EIM85226.1 - 1.8e-22 80.0 34.6 1.8e-22 80.0 24.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIM85226.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) p450 PF00067.17 EIM85228.1 - 3e-25 88.6 0.0 3.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM85229.1 - 4.4e-09 35.3 0.0 5.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIM85230.1 - 6.9e-31 107.2 54.9 3.1e-30 105.1 38.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85230.1 - 9.6e-13 47.4 14.7 9.6e-13 47.4 10.2 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter HAP PF03866.8 EIM85230.1 - 0.095 12.4 6.2 0.2 11.4 1.4 2.5 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) Abhydrolase_6 PF12697.2 EIM85231.1 - 5.9e-19 68.8 0.2 8.1e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM85231.1 - 2.1e-06 27.5 0.0 3.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2716 PF10898.3 EIM85231.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Phosphonate-bd PF12974.2 EIM85231.1 - 0.055 12.8 0.0 0.74 9.1 0.0 2.3 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein ICMT PF04140.9 EIM85232.1 - 7.9e-13 48.4 0.4 9.6e-13 48.1 0.3 1.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM85232.1 - 9.9e-10 38.4 2.1 2.4e-09 37.2 1.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM85232.1 - 5.9e-07 28.3 0.1 7e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DsbD_2 PF13386.1 EIM85232.1 - 0.0007 19.3 0.6 0.0008 19.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF1295 PF06966.7 EIM85232.1 - 0.004 16.4 0.1 0.0043 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIM85234.1 - 1.1e-09 38.3 0.1 1.3e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM85234.1 - 1.1e-06 28.7 0.6 1.3e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase MFS_1 PF07690.11 EIM85235.1 - 2.1e-09 36.5 13.6 2.4e-09 36.3 9.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85235.1 - 0.0002 20.0 7.1 0.00023 19.8 4.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter SdpI PF13630.1 EIM85235.1 - 1.6 8.5 6.0 0.2 11.3 0.6 2.2 2 1 0 2 2 2 0 SdpI/YhfL protein family Integrin_b_cyt PF08725.6 EIM85237.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Helitron_like_N PF14214.1 EIM85238.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIM85239.1 - 0.00091 18.2 0.0 0.00099 18.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EIM85239.1 - 0.072 13.0 1.6 0.32 10.9 0.6 1.9 1 1 1 2 2 2 0 AAA ATPase domain PIF1 PF05970.9 EIM85240.1 - 0.0003 19.8 0.1 0.00043 19.3 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIM85240.1 - 0.11 12.0 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 EIM85241.1 - 0.078 11.9 0.2 0.097 11.6 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase UvrD_C_2 PF13538.1 EIM85242.1 - 0.018 15.1 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain tRNA_anti-codon PF01336.20 EIM85243.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MFS_1 PF07690.11 EIM85244.1 - 1e-08 34.3 22.0 1.3e-08 34.0 15.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85244.1 - 0.061 11.9 16.9 0.069 11.7 11.7 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter ABC2_membrane_2 PF12679.2 EIM85244.1 - 1.2 7.9 9.4 1.3 7.8 6.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PRRSV_2b PF07069.6 EIM85244.1 - 2.1 8.6 4.6 2.8 8.3 0.8 2.7 2 1 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Rhomboid PF01694.17 EIM85244.1 - 5 7.1 11.5 6.7 6.7 7.9 1.4 1 1 0 1 1 1 0 Rhomboid family ADH_zinc_N PF00107.21 EIM85245.1 - 3.9e-17 62.0 0.7 5.8e-17 61.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM85245.1 - 3.1e-14 53.9 0.1 6.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM85245.1 - 3.5e-05 23.5 0.0 0.0004 20.1 0.0 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain dTDP_sugar_isom PF00908.12 EIM85245.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase FAD_binding_3 PF01494.14 EIM85246.1 - 6.8e-21 74.7 0.0 2.8e-20 72.7 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 EIM85246.1 - 1.5e-09 37.2 0.1 7.6e-06 25.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM85246.1 - 1.6e-08 34.4 0.3 3.3e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM85246.1 - 4.1e-07 29.1 0.1 6.2e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIM85246.1 - 1.1e-05 24.5 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM85246.1 - 1.8e-05 24.6 0.0 0.00015 21.6 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85246.1 - 0.00012 20.7 0.0 0.00093 17.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EIM85246.1 - 0.0011 18.1 0.1 0.23 10.4 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIM85246.1 - 0.0021 18.1 0.0 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM85246.1 - 0.0049 15.9 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIM85246.1 - 0.0066 16.8 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM85246.1 - 0.0075 15.1 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIM85246.1 - 0.019 14.7 0.0 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIM85246.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 EIM85248.1 - 4.8e-40 137.3 43.5 1.1e-39 136.2 30.1 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM85248.1 - 1.9e-19 69.3 11.7 2.7e-19 68.8 8.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM85248.1 - 5e-11 41.8 12.3 5e-11 41.8 8.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.15 EIM85248.1 - 0.0025 17.2 15.1 0.016 14.6 4.8 3.1 2 1 0 2 2 2 2 Haemolysin-III related Thaumatin PF00314.12 EIM85249.1 - 4.7e-05 22.9 9.0 0.013 14.9 0.1 3.7 2 1 2 4 4 4 2 Thaumatin family HEV_ORF1 PF02444.11 EIM85249.1 - 4.4 7.5 7.8 0.98 9.6 1.1 2.4 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) UPF0697 PF15117.1 EIM85250.1 - 0.09 12.5 0.2 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 FAD_binding_3 PF01494.14 EIM85251.1 - 2.2e-13 49.9 0.0 2.4e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM85251.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM85251.1 - 0.06 11.9 0.0 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.5 EIM85251.1 - 0.21 10.3 0.0 0.37 9.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Peptidase_M20 PF01546.23 EIM85252.1 - 1.6e-22 79.9 0.0 2.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM85252.1 - 1.9e-09 37.2 0.0 5.7e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3328 PF11807.3 EIM85253.1 - 1.3e-18 67.5 0.3 1.9e-18 66.9 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DNA_Packaging PF11053.3 EIM85253.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme But2 PF09792.4 EIM85254.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain dsrm PF00035.20 EIM85260.1 - 0.056 14.0 0.9 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif F-box PF00646.28 EIM85261.1 - 3.4e-07 29.7 0.6 9.8e-07 28.2 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM85261.1 - 0.0016 18.1 0.9 0.0043 16.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like DUF2939 PF11159.3 EIM85265.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4066 PF13278.1 EIM85269.1 - 0.033 13.4 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative amidotransferase DUF11 PF01345.13 EIM85269.1 - 0.053 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF11 Y1_Tnp PF01797.11 EIM85270.1 - 0.11 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Transposase IS200 like AAA PF00004.24 EIM85272.1 - 6.8e-40 136.3 1.2 4.1e-16 59.3 0.0 5.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EIM85272.1 - 9.2e-39 132.8 0.0 2.5e-38 131.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM85272.1 - 4.8e-22 78.6 20.5 1.6e-17 63.9 0.0 7.2 6 1 0 6 6 5 2 AAA domain AAA_19 PF13245.1 EIM85272.1 - 1.4e-14 53.5 4.1 0.028 14.1 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_5 PF07728.9 EIM85272.1 - 1.6e-11 44.0 3.5 0.2 11.3 0.0 5.8 4 1 1 5 5 5 3 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EIM85272.1 - 2.2e-10 40.4 7.9 0.011 15.2 0.0 6.6 7 1 0 7 7 7 3 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EIM85272.1 - 5.6e-10 40.0 23.5 0.02 15.7 0.0 6.7 7 0 0 7 7 5 4 AAA domain AAA_22 PF13401.1 EIM85272.1 - 9.3e-10 38.7 20.4 0.042 13.9 0.1 9.1 7 3 1 8 8 8 2 AAA domain AAA_16 PF13191.1 EIM85272.1 - 1.6e-08 34.7 9.3 0.36 10.7 0.0 6.0 5 0 0 5 5 5 3 AAA ATPase domain Mg_chelatase PF01078.16 EIM85272.1 - 1.9e-08 33.6 1.4 0.56 9.3 0.0 4.5 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EIM85272.1 - 1.2e-07 31.7 6.1 0.26 11.1 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_30 PF13604.1 EIM85272.1 - 2.9e-07 30.2 23.0 0.022 14.3 0.0 7.6 6 2 2 8 8 7 3 AAA domain IstB_IS21 PF01695.12 EIM85272.1 - 1.8e-06 27.5 0.1 0.92 8.8 0.0 5.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIM85272.1 - 5.1e-06 26.8 17.6 0.59 10.4 0.0 5.8 5 0 0 5 5 4 3 AAA domain RNA_helicase PF00910.17 EIM85272.1 - 1e-05 25.6 1.4 5.7 7.1 0.0 4.7 4 0 0 4 4 4 0 RNA helicase Torsin PF06309.6 EIM85272.1 - 0.00014 21.7 0.2 6.6 6.6 0.0 4.3 4 0 0 4 4 4 0 Torsin PhoH PF02562.11 EIM85272.1 - 0.00033 19.9 0.5 1.3 8.2 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein AAA_24 PF13479.1 EIM85272.1 - 0.00046 19.8 11.0 2.1 7.8 0.5 5.0 5 0 0 5 5 5 3 AAA domain DUF572 PF04502.8 EIM85272.1 - 0.0033 16.7 4.2 0.0033 16.7 2.9 2.3 2 0 0 2 2 1 1 Family of unknown function (DUF572) ADK PF00406.17 EIM85272.1 - 0.04 13.7 4.0 5.2 6.9 0.1 4.0 3 0 0 3 3 3 0 Adenylate kinase AAA_25 PF13481.1 EIM85272.1 - 0.048 13.0 15.3 0.11 11.8 0.0 4.9 5 0 0 5 5 4 0 AAA domain DUF2075 PF09848.4 EIM85272.1 - 0.059 12.3 0.0 0.059 12.3 0.0 6.5 7 1 0 7 7 6 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EIM85272.1 - 0.092 11.8 5.4 12 4.9 0.0 4.4 4 0 0 4 4 4 0 KaiC Guanylate_cyc_2 PF09778.4 EIM85272.1 - 0.17 11.0 0.0 4.1 6.5 0.0 2.6 3 0 0 3 3 3 0 Guanylylate cyclase UvrD_C_2 PF13538.1 EIM85272.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.6 3 0 0 3 3 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 EIM85272.1 - 0.6 9.7 7.4 48 3.5 0.1 4.7 5 0 0 5 5 4 0 NACHT domain AAA_28 PF13521.1 EIM85272.1 - 3.3 7.6 24.6 1.6 8.6 0.1 6.1 5 1 0 5 5 4 0 AAA domain Dynamin_N PF00350.18 EIM85273.1 - 1.3e-09 38.0 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM85273.1 - 8.6e-09 34.5 0.0 0.00022 20.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EIM85273.1 - 1.4e-05 24.8 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM85273.1 - 0.1 12.5 0.1 0.84 9.6 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM85274.1 - 9e-26 90.6 0.2 3e-25 88.9 0.2 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM85274.1 - 1.8e-20 72.9 0.0 1.1e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EIM85274.1 - 1.2e-11 44.3 0.3 4.5e-09 36.0 0.0 2.6 2 0 0 2 2 2 2 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM85274.1 - 0.00022 21.1 0.1 0.0038 17.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EIM85274.1 - 0.0046 16.9 0.0 0.058 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIM85274.1 - 0.0095 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Na_H_Exchanger PF00999.16 EIM85275.1 - 4.5e-38 130.7 39.6 3.2e-37 127.9 27.5 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Dynamin_N PF00350.18 EIM85276.1 - 2e-24 86.2 0.1 8.1e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM85276.1 - 1e-18 67.1 0.0 1.2e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EIM85276.1 - 1.2e-11 44.3 0.0 3.2e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM85276.1 - 3.5e-05 23.7 0.1 0.0007 19.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4095 PF13338.1 EIM85276.1 - 0.0084 16.2 0.1 0.057 13.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4095) Miro PF08477.8 EIM85276.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein HTH_6 PF01418.12 EIM85277.1 - 0.027 14.1 0.2 0.061 13.0 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Sds3 PF08598.6 EIM85277.1 - 0.036 13.5 0.1 0.079 12.4 0.1 1.5 1 0 0 1 1 1 0 Sds3-like HALZ PF02183.13 EIM85277.1 - 0.1 12.3 0.7 0.34 10.6 0.5 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper Gp58 PF07902.6 EIM85277.1 - 0.17 10.0 0.4 0.39 8.8 0.0 1.6 2 0 0 2 2 2 0 gp58-like protein Mto2_bdg PF12808.2 EIM85277.1 - 0.77 9.9 5.2 0.84 9.7 0.0 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GED PF02212.13 EIM85279.1 - 0.00041 20.1 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.15 EIM85279.1 - 0.0017 17.2 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region ParD PF09386.5 EIM85279.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Antitoxin ParD Tyrosinase PF00264.15 EIM85280.1 - 5.8e-49 167.2 3.2 1.1e-48 166.3 2.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase TPR_17 PF13431.1 EIM85280.1 - 0.087 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM85280.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 TPR repeat GTP_CH_N PF12471.3 EIM85281.1 - 1.5e-62 210.7 0.0 2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal FMO-like PF00743.14 EIM85283.1 - 1e-18 66.8 0.0 2.4e-13 49.1 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM85283.1 - 6e-18 65.6 0.0 1.7e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM85283.1 - 4.4e-10 38.9 0.1 1.2e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM85283.1 - 5.2e-07 29.7 0.0 1.9e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM85283.1 - 1.9e-06 28.0 0.5 0.00078 19.5 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EIM85283.1 - 4.3e-05 22.7 0.6 0.00081 18.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIM85283.1 - 5.2e-05 23.1 0.0 0.0002 21.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM85283.1 - 0.00022 21.5 0.1 0.077 13.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIM85283.1 - 0.00044 20.2 0.1 0.031 14.2 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.19 EIM85283.1 - 0.00053 19.0 0.1 0.0092 14.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM85283.1 - 0.0016 18.2 0.0 0.011 15.5 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIM85283.1 - 0.0018 17.9 0.1 0.59 9.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIM85283.1 - 0.0019 17.3 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 EIM85283.1 - 0.003 17.6 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 EIM85283.1 - 0.0075 15.2 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 EIM85283.1 - 0.009 15.4 0.1 0.37 10.2 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIM85283.1 - 0.014 13.9 0.1 0.037 12.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.16 EIM85283.1 - 0.026 14.3 0.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 ThiF family GIDA PF01134.17 EIM85283.1 - 0.039 12.8 0.1 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EIM85283.1 - 0.064 12.3 0.0 0.43 9.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 EIM85283.1 - 0.071 13.3 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding SnoaL_4 PF13577.1 EIM85283.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain BTB PF00651.26 EIM85285.1 - 3.1e-05 23.9 0.5 0.00012 21.9 0.4 1.9 1 1 0 1 1 1 1 BTB/POZ domain Thioredoxin_8 PF13905.1 EIM85285.1 - 0.0079 16.3 0.0 0.96 9.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like BTB PF00651.26 EIM85286.1 - 6.7e-05 22.8 0.1 0.00017 21.5 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM85287.1 - 6.1e-07 29.4 0.0 1.6e-06 28.0 0.0 1.6 1 1 1 2 2 2 1 BTB/POZ domain Ribos_L4_asso_C PF14374.1 EIM85287.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain BTB PF00651.26 EIM85288.1 - 1.8e-05 24.6 0.1 5.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain LicD PF04991.8 EIM85288.1 - 0.079 13.0 0.1 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 LicD family DUF883 PF05957.8 EIM85289.1 - 0.0028 18.0 3.3 0.42 11.0 2.5 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF3708 PF12501.3 EIM85289.1 - 0.042 13.6 2.5 4 7.2 0.8 2.2 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF1020 PF06255.8 EIM85289.1 - 0.045 12.9 1.3 0.063 12.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1020) Gly-zipper_Omp PF13488.1 EIM85289.1 - 0.079 12.6 6.6 0.31 10.7 0.7 2.8 2 1 0 2 2 2 0 Glycine zipper HisKA_3 PF07730.8 EIM85289.1 - 4.1 7.8 8.2 1.4 9.3 3.0 2.0 2 0 0 2 2 2 0 Histidine kinase NmrA PF05368.8 EIM85292.1 - 1.1e-15 57.5 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EIM85292.1 - 0.00091 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIM85292.1 - 0.0047 16.9 1.3 0.018 15.0 0.9 2.0 1 1 0 1 1 1 1 NADH(P)-binding DUF1669 PF07894.7 EIM85292.1 - 0.042 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) adh_short PF00106.20 EIM85292.1 - 0.046 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF2325 PF10087.4 EIM85292.1 - 0.11 12.3 0.1 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF1501 PF07394.7 EIM85292.1 - 0.11 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3602 PF12223.3 EIM85293.1 - 5.3e-25 87.6 43.1 2.4e-06 27.8 1.1 6.3 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) DUF629 PF04780.7 EIM85294.1 - 4.8e-05 22.0 0.3 7.8e-05 21.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) CBFD_NFYB_HMF PF00808.18 EIM85295.1 - 3.3e-20 71.9 1.1 5.6e-20 71.1 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIM85295.1 - 2.9e-09 36.9 0.0 4.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2201_N PF13203.1 EIM85295.1 - 0.0036 16.5 4.6 0.0048 16.1 3.2 1.3 1 0 0 1 1 1 1 Putative metallopeptidase domain CENP-X PF09415.5 EIM85295.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 EIM85295.1 - 0.12 12.3 0.2 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Activator_LAG-3 PF11498.3 EIM85295.1 - 4 6.0 20.2 5.5 5.6 14.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1631 PF07793.6 EIM85295.1 - 4.1 5.4 11.8 3.7 5.5 7.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4175 PF13779.1 EIM85295.1 - 7.5 4.1 23.8 9.6 3.7 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 EIM85295.1 - 7.9 4.5 24.3 12 3.9 16.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1793 PF08760.6 EIM85296.1 - 2.3e-57 193.5 0.2 4.2e-57 192.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) WD40 PF00400.27 EIM85298.1 - 8.8e-47 155.3 5.6 5.6e-13 48.2 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 EIM85298.1 - 5e-09 36.0 0.2 1.4e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EIM85298.1 - 8.8e-06 24.1 1.0 0.15 10.1 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 AAA_16 PF13191.1 EIM85298.1 - 0.00018 21.5 0.0 0.00073 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIM85298.1 - 0.0002 21.0 0.0 0.00051 19.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM85298.1 - 0.011 15.8 0.0 0.072 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nucleoporin_N PF08801.6 EIM85298.1 - 0.012 14.3 1.4 0.65 8.6 0.4 2.8 1 1 2 3 3 3 0 Nup133 N terminal like NTPase_1 PF03266.10 EIM85298.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 EIM85298.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.15 EIM85298.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.1 EIM85298.1 - 0.15 12.8 0.2 0.59 10.9 0.0 2.2 2 1 0 2 2 1 0 AAA domain MFS_1 PF07690.11 EIM85299.1 - 1.9e-42 145.2 69.8 1.4e-32 112.7 10.7 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EIM85299.1 - 4e-09 35.2 7.8 4e-09 35.2 5.4 2.2 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.26 EIM85300.1 - 8.5e-23 79.8 2.4 2.3e-22 78.4 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EIM85300.1 - 3.9e-20 71.2 11.0 3.7e-13 48.9 0.2 5.2 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EIM85300.1 - 1.6e-16 58.8 10.9 0.00036 20.2 0.0 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIM85300.1 - 1.3e-15 56.2 0.6 0.00018 20.9 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM85300.1 - 1.6e-13 50.8 18.3 1.9e-06 28.3 0.4 5.5 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIM85300.1 - 4.4e-13 48.5 13.5 0.0014 19.0 0.1 7.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM85300.1 - 6.1e-13 48.9 16.1 6.5e-07 29.6 0.2 5.9 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIM85300.1 - 1e-11 44.5 3.9 5e-06 26.2 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM85300.1 - 1e-09 38.3 3.6 1.9e-06 27.9 0.2 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIM85300.1 - 1.4e-09 37.0 1.1 1.7 8.6 0.0 6.6 5 2 2 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM85300.1 - 2.3e-08 33.9 10.0 0.43 11.1 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM85300.1 - 6.3e-08 32.2 2.7 0.0013 18.7 0.3 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM85300.1 - 2.7e-06 26.7 2.8 0.16 11.8 0.0 5.6 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM85300.1 - 0.00011 22.0 15.3 0.013 15.4 0.3 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIM85300.1 - 0.00056 20.0 16.0 0.16 12.4 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.12 EIM85300.1 - 0.0034 17.6 11.4 0.36 11.1 0.0 4.2 2 2 1 3 3 3 2 Bacterial transcriptional activator domain DUF3808 PF10300.4 EIM85300.1 - 0.0067 15.0 0.5 0.091 11.3 0.0 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF3808) CCAP PF11105.3 EIM85300.1 - 0.013 15.2 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a MIT PF04212.13 EIM85300.1 - 0.02 14.7 1.1 15 5.5 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4363 PF14276.1 EIM85300.1 - 0.1 12.2 1.8 0.86 9.3 0.1 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) HemY_N PF07219.8 EIM85300.1 - 1.1 8.7 4.6 0.75 9.3 0.5 2.7 2 1 0 3 3 2 0 HemY protein N-terminus TPR_20 PF14561.1 EIM85300.1 - 7.2 6.8 15.0 4.4 7.4 0.1 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_3 PF00933.16 EIM85301.1 - 3.5e-55 187.0 0.0 4.6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM85301.1 - 1.1e-51 175.5 0.0 1.7e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM85301.1 - 4.1e-22 77.9 1.6 1.6e-21 76.0 1.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_92 PF07971.7 EIM85302.1 - 3.8e-147 490.9 1.3 4.7e-147 490.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 TIP49 PF06068.8 EIM85305.1 - 1.2e-174 580.6 0.0 1.4e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIM85305.1 - 8.6e-10 38.9 0.1 2.5e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM85305.1 - 3.2e-08 32.8 0.3 9.6e-07 28.0 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIM85305.1 - 6.7e-08 32.7 0.0 6.6e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIM85305.1 - 7.9e-06 25.6 0.1 0.0043 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM85305.1 - 8.5e-06 25.9 0.1 0.038 14.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM85305.1 - 0.00043 19.9 0.2 0.0021 17.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EIM85305.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM85305.1 - 0.0018 18.1 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM85305.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIM85305.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EIM85305.1 - 0.025 14.4 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EIM85305.1 - 0.03 13.5 0.1 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIM85305.1 - 0.036 13.1 0.1 0.084 11.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIM85305.1 - 0.046 14.5 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIM85305.1 - 0.046 13.1 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2584 PF10763.4 EIM85305.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) DUF2075 PF09848.4 EIM85305.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EIM85305.1 - 0.23 10.6 2.1 0.44 9.7 0.1 2.3 3 0 0 3 3 3 0 PhoH-like protein Glyco_hydro_61 PF03443.9 EIM85306.1 - 3.6e-70 236.1 0.2 4.5e-70 235.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Epimerase PF01370.16 EIM85307.1 - 2.4e-19 69.7 0.0 3.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM85307.1 - 4.4e-14 51.8 0.0 1.1e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM85307.1 - 1.1e-13 51.5 0.1 3.2e-13 50.0 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM85307.1 - 2.7e-09 36.3 0.0 1.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM85307.1 - 1.1e-05 24.8 0.1 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM85307.1 - 0.0014 18.6 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Abhydrolase_6 PF12697.2 EIM85309.1 - 1.3e-31 110.2 0.3 1.8e-31 109.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM85309.1 - 4.3e-17 62.4 0.4 4.7e-16 59.0 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM85309.1 - 3.9e-12 46.1 0.0 1.5e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM85309.1 - 0.0069 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 EIM85309.1 - 0.065 13.1 0.4 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ndr PF03096.9 EIM85309.1 - 0.19 10.1 0.0 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family PNP_UDP_1 PF01048.15 EIM85313.1 - 9.6e-34 116.3 0.0 1.2e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ERM PF00769.14 EIM85314.1 - 0.17 11.4 103.5 0.033 13.7 15.7 6.0 1 1 3 5 5 5 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EIM85314.1 - 0.21 11.9 70.1 0.66 10.3 2.2 9.3 1 1 9 10 10 10 0 Protein of unknown function (DUF972) SH3_1 PF00018.23 EIM85317.1 - 4.9e-05 22.6 0.0 0.0001 21.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM85317.1 - 5.3e-05 22.7 0.1 5.3e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIM85317.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Patatin PF01734.17 EIM85318.1 - 1e-17 64.7 0.0 2.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EIM85318.1 - 2.6e-09 36.3 0.0 5.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EIM85318.1 - 2.8e-05 24.2 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIM85318.1 - 0.0022 17.6 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EIM85318.1 - 0.0037 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EIM85318.1 - 0.0061 16.5 0.3 0.054 13.4 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EIM85318.1 - 0.011 15.6 0.0 0.099 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain HMG_box_5 PF14887.1 EIM85318.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Glyco_hydro_28 PF00295.12 EIM85320.1 - 5.5e-26 91.2 0.5 7.3e-26 90.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EIM85320.1 - 1.6e-05 25.1 0.9 4.7e-05 23.6 0.6 1.8 1 1 0 1 1 1 1 Pectate lyase superfamily protein ABC_tran PF00005.22 EIM85321.1 - 3.6e-31 108.2 0.2 2.8e-28 98.9 0.0 3.2 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.18 EIM85321.1 - 3.3e-16 59.5 7.9 1.1e-09 38.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM85321.1 - 0.00019 20.7 0.0 0.015 14.5 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM85321.1 - 0.0005 20.1 0.1 0.073 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIM85321.1 - 0.00082 19.2 0.5 0.003 17.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 EIM85321.1 - 0.019 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EIM85321.1 - 0.027 14.0 0.1 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EIM85321.1 - 0.042 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EIM85321.1 - 0.068 13.1 0.2 0.85 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EIM85321.1 - 0.13 12.3 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2360 PF10152.4 EIM85321.1 - 0.26 11.5 1.0 33 4.7 0.0 3.2 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2654 PF10849.3 EIM85324.1 - 0.045 13.4 2.3 0.12 12.1 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) PEARLI-4 PF05278.7 EIM85324.1 - 0.83 8.9 4.9 0.33 10.2 1.1 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pkinase PF00069.20 EIM85325.1 - 6.6e-10 38.5 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85325.1 - 0.0054 15.8 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cortex-I_coil PF09304.5 EIM85326.1 - 0.0067 16.4 3.1 0.01 15.8 2.2 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil Syntaxin_2 PF14523.1 EIM85326.1 - 0.0099 15.8 0.4 0.014 15.3 0.3 1.4 1 0 0 1 1 1 1 Syntaxin-like protein Nup54 PF13874.1 EIM85326.1 - 0.01 15.5 3.6 0.019 14.6 2.2 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 GAS PF13851.1 EIM85326.1 - 0.01 15.0 3.9 0.016 14.4 2.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIM85326.1 - 0.011 14.7 3.0 0.012 14.6 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PV-1 PF06637.6 EIM85326.1 - 0.016 13.7 2.3 0.017 13.7 1.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) bZIP_1 PF00170.16 EIM85326.1 - 0.019 14.9 3.1 0.16 11.9 1.0 2.6 2 1 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EIM85326.1 - 0.023 14.2 2.3 0.025 14.1 1.6 1.1 1 0 0 1 1 1 0 IncA protein Leu_zip PF15294.1 EIM85326.1 - 0.03 13.4 2.2 0.034 13.2 1.5 1.1 1 0 0 1 1 1 0 Leucine zipper AAA_32 PF13654.1 EIM85326.1 - 0.08 11.5 0.7 0.087 11.4 0.5 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 EIM85326.1 - 0.11 12.4 2.7 0.26 11.1 1.7 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIM85326.1 - 0.18 12.1 2.4 4.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 EIM85326.1 - 0.18 11.5 4.5 0.42 10.3 0.4 2.8 1 1 0 2 2 2 0 Homeobox associated leucine zipper Enkurin PF13864.1 EIM85326.1 - 0.22 11.7 4.7 0.3 11.3 3.3 1.3 1 0 0 1 1 1 0 Calmodulin-binding DivIC PF04977.10 EIM85326.1 - 0.35 10.3 6.3 0.14 11.6 2.6 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EIM85326.1 - 1.7 9.0 9.7 8.5 6.7 3.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF1875 PF08961.5 EIM85326.1 - 2.3 7.4 6.4 1.1 8.5 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) bZIP_2 PF07716.10 EIM85326.1 - 9.3 6.1 12.2 0.23 11.3 1.0 2.7 3 0 0 3 3 2 0 Basic region leucine zipper MAGE_N PF12440.3 EIM85327.1 - 0.77 10.0 13.3 1.5 9.1 9.2 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Epimerase PF01370.16 EIM85328.1 - 1.1e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM85328.1 - 4.4e-10 38.9 0.0 1.3e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EIM85328.1 - 1.1e-07 30.8 0.0 2.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIM85328.1 - 5.4e-05 23.1 0.1 9.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM85328.1 - 0.0012 17.7 0.1 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIM85328.1 - 0.0022 18.0 0.1 0.016 15.2 0.1 2.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM85328.1 - 0.025 14.2 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 KR domain DUF3328 PF11807.3 EIM85330.1 - 9.7e-08 31.9 0.5 5.5e-07 29.5 0.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SNO PF01174.14 EIM85331.1 - 6.6e-52 175.8 0.0 1.7e-41 141.9 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EIM85331.1 - 2.7e-08 33.5 0.3 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EIM85331.1 - 9.4e-05 21.7 0.2 0.00014 21.1 0.2 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EIM85331.1 - 0.00038 20.2 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 EIM85331.1 - 0.0022 17.4 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4154 PF13689.1 EIM85331.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) GATase PF00117.23 EIM85331.1 - 0.13 11.7 2.2 0.95 8.8 0.0 2.6 2 1 1 3 3 3 0 Glutamine amidotransferase class-I Med3 PF11593.3 EIM85332.1 - 2 7.5 7.5 4.2 6.5 5.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pyridox_oxidase PF01243.15 EIM85333.1 - 0.0056 16.6 0.0 3 7.9 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase COesterase PF00135.23 EIM85334.1 - 1.4e-96 324.3 0.0 1.7e-96 324.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM85334.1 - 5e-06 26.2 0.6 0.00012 21.7 0.6 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM85334.1 - 0.021 14.5 0.3 0.05 13.3 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2424 PF10340.4 EIM85334.1 - 0.13 10.9 0.0 0.25 9.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) RFC1 PF08519.7 EIM85335.1 - 3.8e-50 169.6 0.0 4.9e-49 166.0 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EIM85335.1 - 2.9e-13 49.7 0.0 1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EIM85335.1 - 6.8e-11 42.4 0.0 1.7e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIM85335.1 - 3.8e-07 29.1 0.2 2.9e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EIM85335.1 - 0.00073 19.2 0.0 0.007 16.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIM85335.1 - 0.00092 18.9 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM85335.1 - 0.0037 17.3 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM85335.1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIM85335.1 - 0.0063 17.3 0.1 0.044 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM85335.1 - 0.0095 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM85335.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM85335.1 - 0.036 14.0 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain LolB PF03550.9 EIM85335.1 - 0.061 12.9 0.1 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB DNA_binding_1 PF01035.15 EIM85336.1 - 1.4e-20 72.7 0.0 2.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Neuroparsin PF07327.6 EIM85338.1 - 0.076 13.2 0.5 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Neuroparsin AAA PF00004.24 EIM85339.1 - 4.3e-46 156.3 0.0 9.1e-41 139.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM85339.1 - 4.6e-07 30.0 0.0 6.6e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EIM85339.1 - 7e-06 25.5 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EIM85339.1 - 5e-05 23.4 0.1 0.004 17.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EIM85339.1 - 0.00021 21.2 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIM85339.1 - 0.00066 19.4 0.0 0.0029 17.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIM85339.1 - 0.00087 18.9 0.3 0.0049 16.5 0.0 2.4 3 0 0 3 3 1 1 Part of AAA domain AAA_17 PF13207.1 EIM85339.1 - 0.0043 17.8 0.2 0.027 15.3 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 EIM85339.1 - 0.0096 15.3 0.1 0.033 13.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM85339.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.8 EIM85339.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EIM85339.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EIM85339.1 - 0.034 13.7 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIM85339.1 - 0.063 13.3 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EIM85339.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 EIM85339.1 - 0.064 12.3 0.1 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EIM85339.1 - 0.069 12.1 0.0 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EIM85339.1 - 0.084 12.3 0.0 2.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EIM85339.1 - 0.088 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EIM85339.1 - 0.098 12.9 0.0 0.098 12.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EIM85339.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EIM85339.1 - 0.26 10.1 0.0 0.46 9.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EIM85339.1 - 0.48 10.3 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Torsin PIF1 PF05970.9 EIM85339.1 - 0.69 8.8 0.0 1.1 8.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TMF_DNA_bd PF12329.3 EIM85340.1 - 0.0041 16.8 7.3 0.01 15.6 5.1 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding YccJ PF13993.1 EIM85340.1 - 0.056 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 YccJ-like protein RBD-FIP PF09457.5 EIM85340.1 - 1.1 9.1 4.3 0.41 10.4 0.4 2.2 2 0 0 2 2 2 0 FIP domain Peptidase_S49_N PF08496.5 EIM85340.1 - 2.7 7.7 12.7 0.23 11.2 1.4 2.6 2 1 0 2 2 2 0 Peptidase family S49 N-terminal GST_N_3 PF13417.1 EIM85341.1 - 1.8e-11 44.1 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM85341.1 - 5.9e-08 33.1 0.0 3.4e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM85341.1 - 6e-08 32.4 0.0 2.9e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM85341.1 - 2.1e-07 30.9 0.0 6.8e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM85341.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM85341.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 EIM85341.1 - 0.048 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain YqcI_YcgG PF08892.6 EIM85342.1 - 2.3e-61 207.1 0.0 2.8e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 YqcI/YcgG family Catalase PF00199.14 EIM85343.1 - 6.8e-155 515.4 0.4 8.2e-155 515.2 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIM85343.1 - 7.8e-12 44.8 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2204 PF09970.4 EIM85344.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Ribonuc_L-PSP PF01042.16 EIM85346.1 - 3.2e-31 107.6 0.0 3.5e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.2 EIM85347.1 - 0.058 13.1 0.6 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.17 EIM85349.1 - 3.9e-80 270.0 0.0 5e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MSP1_C PF07462.6 EIM85350.1 - 0.45 8.8 1.5 0.51 8.6 1.0 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Vert_HS_TF PF06546.6 EIM85350.1 - 3 7.1 9.9 3.2 7.0 6.6 1.3 1 1 0 1 1 1 0 Vertebrate heat shock transcription factor RRM_1 PF00076.17 EIM85351.1 - 4.8e-33 112.6 0.5 1.2e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85351.1 - 2e-26 91.7 0.3 5.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85351.1 - 1.4e-11 44.0 0.2 1.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM85351.1 - 0.0028 17.3 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIM85351.1 - 0.037 13.8 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Suf PF05843.9 EIM85352.1 - 7.7e-57 193.1 1.5 3.1e-55 187.8 0.0 2.9 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EIM85352.1 - 2.8e-11 43.0 0.1 0.024 15.2 0.0 7.2 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM85352.1 - 2.1e-09 37.5 0.0 0.15 12.4 0.1 5.0 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIM85352.1 - 1.4e-07 31.9 3.1 0.048 14.3 0.1 4.8 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIM85352.1 - 6.5e-06 25.4 0.9 0.036 13.1 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM85352.1 - 1.8e-05 24.2 0.0 0.088 12.4 0.0 3.6 3 1 0 4 4 4 2 TPR repeat TPR_6 PF13174.1 EIM85352.1 - 0.0029 17.9 0.7 5.6 7.6 0.0 4.3 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIM85352.1 - 0.0053 16.5 0.0 7.3 6.7 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF1886 PF09171.5 EIM85352.1 - 0.006 15.6 0.1 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1886) TPR_7 PF13176.1 EIM85352.1 - 0.033 14.0 0.1 1.2e+02 2.8 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4456 PF14644.1 EIM85352.1 - 0.083 12.1 0.7 8.4 5.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) TPR_17 PF13431.1 EIM85352.1 - 0.088 13.0 0.2 9.4 6.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIM85352.1 - 8.7 6.1 7.7 2.9 7.6 0.1 3.6 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 Glyco_hydro_85 PF03644.8 EIM85353.1 - 1.1e-70 238.3 0.0 1.5e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 AA_permease PF00324.16 EIM85354.1 - 4.5e-114 381.4 40.4 5.4e-114 381.1 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM85354.1 - 2.3e-29 102.2 39.7 3.2e-29 101.7 27.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EIM85354.1 - 0.063 12.8 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) OPT PF03169.10 EIM85355.1 - 1.7e-125 419.8 51.8 1.9e-125 419.6 35.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 EIM85356.1 - 2.2e-16 59.5 16.6 1.3e-15 56.9 11.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EIM85356.1 - 5.5e-14 52.0 0.7 5.5e-14 52.0 0.5 2.2 3 0 0 3 3 3 1 Nodulin-like p31comet PF06581.7 EIM85358.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Nop14 PF04147.7 EIM85358.1 - 4.2 5.1 6.4 6.5 4.5 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family Peptidase_S10 PF00450.17 EIM85359.1 - 2.4e-81 274.0 0.0 3.2e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HD PF01966.17 EIM85360.1 - 3.5e-10 39.9 0.0 9.4e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 HD domain HD PF01966.17 EIM85361.1 - 8.7e-11 41.8 1.5 1.5e-10 41.1 0.2 2.0 2 0 0 2 2 2 1 HD domain Tcf25 PF04910.9 EIM85364.1 - 4.1e-68 229.9 0.0 6.3e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 FGE-sulfatase PF03781.11 EIM85365.1 - 3.6e-21 75.6 4.6 1.9e-11 43.8 0.3 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIM85365.1 - 2.5e-09 37.5 1.2 4.3e-09 36.7 0.8 1.4 1 0 0 1 1 1 1 DinB superfamily His_Phos_2 PF00328.17 EIM85366.1 - 5.7e-31 108.1 0.0 7.8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 EIM85367.1 - 6.7e-36 123.7 48.2 3.5e-35 121.3 33.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM85367.1 - 7.8e-06 24.3 10.9 1.4e-05 23.4 7.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NmrA PF05368.8 EIM85368.1 - 1.4e-18 66.9 0.0 1.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM85368.1 - 1.7e-13 50.9 0.0 2.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM85368.1 - 5.2e-06 26.0 0.0 2.1e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM85368.1 - 0.00082 18.1 0.0 0.0014 17.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family OTCace_N PF02729.16 EIM85368.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NAD_binding_4 PF07993.7 EIM85368.1 - 0.022 13.6 0.0 0.088 11.7 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein KR PF08659.5 EIM85368.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EIM85368.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.8 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM85368.1 - 0.087 11.7 0.0 0.4 9.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1655 PF07868.6 EIM85368.1 - 0.1 12.6 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) AP_endonuc_2 PF01261.19 EIM85368.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Npa1 PF11707.3 EIM85369.1 - 8.2e-73 245.2 0.0 1.4e-71 241.2 0.0 2.7 2 1 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EIM85369.1 - 0.0055 16.8 0.1 0.16 12.1 0.0 3.5 3 0 0 3 3 3 1 Creb binding IpaB_EvcA PF03278.8 EIM85369.1 - 0.26 10.5 0.5 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 IpaB/EvcA family CMD PF02627.15 EIM85370.1 - 3e-19 68.6 0.1 6.9e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.10 EIM85371.1 - 3.1e-35 121.4 0.0 5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIM85371.1 - 7.6e-23 80.8 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EIM85371.1 - 0.019 13.7 0.0 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EIM85371.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 EIM85372.1 - 1.7e-18 66.5 35.2 7.9e-18 64.2 18.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PRCH PF03967.8 EIM85372.1 - 0.00015 21.3 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Photosynthetic reaction centre, H-chain N-terminal region DUF1228 PF06779.9 EIM85372.1 - 0.099 12.6 2.8 0.85 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ADH_N PF08240.7 EIM85373.1 - 1.2e-22 79.7 0.6 2e-22 79.0 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM85373.1 - 1.7e-19 69.6 0.0 2.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM85373.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DIOX_N PF14226.1 EIM85374.1 - 7e-19 68.4 0.1 6e-17 62.2 0.0 2.7 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM85374.1 - 2e-12 47.2 0.1 5.8e-12 45.7 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM85375.1 - 1.1e-18 67.8 0.1 3.5e-17 63.0 0.0 2.7 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM85375.1 - 7.6e-13 48.5 0.0 2.3e-12 47.0 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Exo_endo_phos PF03372.18 EIM85376.1 - 7.1e-24 85.1 0.2 1.5e-23 84.0 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family P2 PF07194.6 EIM85376.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain WD40 PF00400.27 EIM85376.1 - 0.73 9.8 3.4 4.7 7.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Miff PF05644.6 EIM85377.1 - 9.1 5.8 7.6 16 5.0 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Mannitol_dh_C PF08125.8 EIM85379.1 - 3.8e-48 163.8 0.0 2.2e-43 148.2 0.0 2.2 2 0 0 2 2 2 2 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EIM85379.1 - 1.9e-21 76.6 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Retrotrans_gag PF03732.12 EIM85380.1 - 1e-14 54.3 0.1 4e-14 52.4 0.0 2.0 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM85380.1 - 1.2e-05 25.0 9.9 0.0061 16.4 1.6 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.1 EIM85380.1 - 0.029 14.0 1.8 0.089 12.4 1.3 1.8 1 1 0 1 1 1 0 Nudix N-terminal zf-CCHC_4 PF14392.1 EIM85380.1 - 0.1 12.3 4.6 2.6 7.7 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Mannitol_dh_C PF08125.8 EIM85381.1 - 1.6e-49 168.2 0.0 8.8e-45 152.7 0.0 2.5 3 0 0 3 3 3 2 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EIM85381.1 - 6.5e-22 78.1 0.0 1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain RA PF00788.18 EIM85385.1 - 1.4e-13 51.1 0.0 2.5e-11 43.8 0.0 3.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIM85385.1 - 1.3e-05 24.4 0.2 3.7e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIM85385.1 - 0.00043 19.8 0.0 0.0012 18.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LAMP2 PF06126.6 EIM85385.1 - 1.7 6.9 0.2 2.8 6.2 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Actin PF00022.14 EIM85388.1 - 6.2e-93 311.3 0.0 7.3e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIM85388.1 - 0.00072 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein BcrAD_BadFG PF01869.15 EIM85388.1 - 0.026 13.7 0.0 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Rsa3 PF14615.1 EIM85389.1 - 3.5e-13 48.6 0.0 4.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TFIIF_alpha PF05793.7 EIM85389.1 - 0.1 10.9 9.7 0.16 10.3 6.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.4 EIM85389.1 - 0.41 9.2 8.4 0.42 9.2 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Bravo_FIGEY PF13882.1 EIM85389.1 - 3.7 8.5 11.2 7.5 7.5 7.8 1.5 1 0 0 1 1 1 0 Bravo-like intracellular region DUF566 PF04484.7 EIM85389.1 - 6.1 6.2 12.9 7.1 6.0 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ldh_1_N PF00056.18 EIM85391.1 - 2.8e-43 147.1 0.1 4e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIM85391.1 - 3.9e-40 137.3 0.0 5.9e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIM85391.1 - 0.0023 16.6 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM85391.1 - 0.0071 16.3 0.6 0.017 15.1 0.4 1.6 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIM85391.1 - 0.018 15.3 0.1 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIM85391.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 EIM85391.1 - 0.16 11.2 0.2 0.99 8.6 0.1 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DUF1768 PF08719.6 EIM85392.1 - 6.3e-33 113.7 0.0 1.1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1202 PF06717.6 EIM85392.1 - 0.0066 15.7 0.1 0.0099 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) Metallothio_Pro PF02069.11 EIM85392.1 - 0.0088 15.8 9.7 4 7.3 0.3 3.5 3 0 0 3 3 3 3 Prokaryotic metallothionein DUF329 PF03884.9 EIM85392.1 - 0.016 14.7 19.9 1.2 8.6 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-FCS PF06467.9 EIM85392.1 - 0.043 13.4 0.5 0.043 13.4 0.4 4.1 3 2 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif RRN7 PF11781.3 EIM85392.1 - 0.32 10.5 8.2 0.15 11.5 0.3 3.3 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-MYND PF01753.13 EIM85392.1 - 1 9.3 18.7 0.85 9.5 1.4 3.8 3 0 0 3 3 3 0 MYND finger RPAP2_Rtr1 PF04181.8 EIM85392.1 - 3 8.0 12.3 1.2 9.2 0.2 3.2 2 1 1 3 3 3 0 Rtr1/RPAP2 family zf-HIT PF04438.11 EIM85392.1 - 4.9 6.8 26.6 1 9.0 0.2 4.4 3 2 0 3 3 3 0 HIT zinc finger Ecl1 PF12855.2 EIM85392.1 - 9.5 5.6 11.9 8.6 5.7 0.7 3.4 3 0 0 3 3 3 0 Life-span regulatory factor PARP PF00644.15 EIM85393.1 - 6.3e-17 61.6 1.2 3.6e-11 42.8 0.0 3.0 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain PhyH PF05721.8 EIM85394.1 - 5.8e-22 78.7 0.8 1.3e-21 77.6 0.6 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.6 EIM85394.1 - 0.033 13.7 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cyclin_N PF00134.18 EIM85395.1 - 8.2e-12 44.8 0.1 3.1e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIM85395.1 - 0.0014 18.5 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain P_C PF06640.6 EIM85395.1 - 0.036 14.0 1.2 0.062 13.2 0.8 1.3 1 0 0 1 1 1 0 P protein C-terminus TFIIB PF00382.14 EIM85395.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Uso1_p115_C PF04871.8 EIM85396.1 - 0.0012 18.7 0.3 0.0022 17.8 0.2 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.4 EIM85396.1 - 0.095 12.8 0.8 0.26 11.4 0.6 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EIM85396.1 - 0.14 12.4 6.4 0.3 11.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EIM85396.1 - 0.15 12.4 0.6 0.27 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIM85396.1 - 0.48 9.9 3.9 0.94 9.0 2.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Actin PF00022.14 EIM85397.1 - 1.9e-155 517.1 0.0 2.2e-155 516.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EIM85397.1 - 0.077 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cpn60_TCP1 PF00118.19 EIM85399.1 - 2.2e-136 455.3 10.5 2.5e-136 455.1 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPF0489 PF12640.2 EIM85400.1 - 0.12 12.5 1.1 0.37 10.9 0.8 1.8 1 1 0 1 1 1 0 UPF0489 domain zf-C2H2_4 PF13894.1 EIM85400.1 - 0.68 10.4 14.7 0.71 10.3 2.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger PMT PF02366.13 EIM85401.1 - 1.3e-73 247.3 15.0 1.3e-73 247.3 10.4 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIM85401.1 - 6.9e-42 143.1 0.1 1.4e-41 142.1 0.0 1.5 2 0 0 2 2 2 1 MIR domain DUF2063 PF09836.4 EIM85403.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Retrotrans_gag PF03732.12 EIM85404.1 - 1.3e-07 31.6 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM85404.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EIM85405.1 - 2.9e-12 45.9 32.3 5.3e-12 45.1 22.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIM85405.1 - 0.00024 20.6 5.6 0.00024 20.6 3.9 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Actin PF00022.14 EIM85406.1 - 8.2e-156 518.3 0.0 9.3e-156 518.1 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EIM85406.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-C2H2 PF00096.21 EIM85407.1 - 0.0059 16.8 10.2 0.71 10.3 0.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-HYPF PF07503.7 EIM85407.1 - 0.026 13.9 1.2 0.063 12.6 0.9 1.7 1 0 0 1 1 1 0 HypF finger zf-C2H2_4 PF13894.1 EIM85407.1 - 0.13 12.6 12.8 2.8 8.4 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger CCAP PF11105.3 EIM85407.1 - 0.17 11.6 1.4 0.32 10.7 1.0 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Transpos_assoc PF13963.1 EIM85407.1 - 0.51 10.3 3.9 0.5 10.3 0.2 2.3 1 1 1 2 2 2 0 Transposase-associated domain zf-C2H2_4 PF13894.1 EIM85408.1 - 8.9e-06 25.6 15.0 0.092 13.1 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM85408.1 - 2.1e-05 24.5 14.1 0.36 11.2 3.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM85408.1 - 0.00043 20.4 11.2 0.026 14.8 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EIM85408.1 - 0.01 16.0 14.8 0.11 12.8 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain VWA_2 PF13519.1 EIM85409.1 - 2.1e-14 54.0 0.0 2.4e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EIM85409.1 - 1e-05 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EIM85409.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain F-box PF00646.28 EIM85411.1 - 0.12 12.0 4.8 0.49 10.1 1.1 3.0 2 1 0 2 2 2 0 F-box domain EMG1 PF03587.9 EIM85412.1 - 5.1e-76 254.4 0.0 6.4e-76 254.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPRTase PF14681.1 EIM85413.1 - 1.6e-76 256.1 0.0 2.1e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIM85413.1 - 6.1e-05 22.7 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SCO1-SenC PF02630.9 EIM85414.1 - 1.2e-55 187.7 0.0 1.6e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EIM85414.1 - 7.5e-06 25.6 0.0 1.4e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EIM85414.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like NDUF_B7 PF05676.8 EIM85415.1 - 1.9e-30 104.0 1.1 2.4e-30 103.7 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIM85415.1 - 0.0011 18.6 1.7 0.0019 17.8 1.2 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cauli_VI PF01693.11 EIM85417.1 - 0.0047 16.9 0.2 0.0099 15.8 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin YfbU PF03887.9 EIM85418.1 - 0.062 12.8 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 YfbU domain Tet_JBP PF12851.2 EIM85419.1 - 1.9e-06 27.3 0.0 2.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Peptidase_C48 PF02902.14 EIM85422.1 - 0.0019 17.8 1.2 0.0019 17.8 0.8 2.2 2 2 1 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain CAF-1_p150 PF11600.3 EIM85422.1 - 0.0076 15.6 34.7 0.017 14.5 24.0 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EIM85422.1 - 1.8 8.3 19.3 2.6 7.8 13.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1777 PF08648.7 EIM85422.1 - 2 8.0 28.4 3.3 7.3 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DDE_1 PF03184.14 EIM85423.1 - 7.1e-05 22.0 0.0 9.7e-05 21.5 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Lamp PF01299.12 EIM85429.1 - 0.19 10.8 2.8 0.25 10.4 1.9 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Helicase_C PF00271.26 EIM85430.1 - 6.8e-06 25.8 0.4 4.5e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UBN2_2 PF14227.1 EIM85431.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIM85431.1 - 0.0013 18.3 0.1 0.0045 16.5 0.1 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM85431.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EIM85431.1 - 0.075 12.4 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) F-box-like PF12937.2 EIM85432.1 - 1.2e-06 28.1 0.2 7.1e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM85432.1 - 0.015 14.9 0.1 0.015 14.9 0.1 2.8 3 0 0 3 3 3 0 F-box domain YonK PF09642.5 EIM85434.1 - 0.053 13.2 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 YonK protein Paramyxo_ncap PF00973.14 EIM85434.1 - 3.4 6.2 4.2 5.8 5.4 2.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Suf PF05843.9 EIM85436.1 - 0.42 10.2 4.0 0.14 11.8 0.6 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAM PF15320.1 EIM85438.1 - 0.78 10.0 3.4 1.7 8.9 2.4 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Ndc1_Nup PF09531.5 EIM85438.1 - 3.9 5.7 5.1 4.7 5.5 3.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DEAD PF00270.24 EIM85439.1 - 9.3e-30 103.3 0.0 1.1e-28 99.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM85439.1 - 2.4e-09 36.9 0.0 6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ndufs5 PF10200.4 EIM85439.1 - 0.028 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF1253 PF06862.7 EIM85439.1 - 0.1 10.9 0.0 0.62 8.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) DDE_1 PF03184.14 EIM85446.1 - 3.6e-18 65.4 0.0 5.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AvrRpt-cleavage PF05627.6 EIM85446.1 - 0.13 11.3 0.0 0.31 10.0 0.0 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr DUF3656 PF12392.3 EIM85446.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Collagenase PMI_typeI PF01238.16 EIM85447.1 - 1.5e-109 366.4 0.0 1.8e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIM85447.1 - 0.00026 20.4 0.5 0.61 9.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EIM85447.1 - 0.0044 16.7 0.0 0.98 9.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CGI-121 PF08617.5 EIM85448.1 - 6.3e-41 139.7 0.9 7.2e-41 139.5 0.6 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.15 EIM85449.1 - 3.3e-53 177.7 0.1 2.2e-26 91.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EIM85449.1 - 2.9e-20 72.8 0.0 1.2e-09 38.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EIM85449.1 - 5.6e-09 36.1 0.5 0.0011 19.2 0.1 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM85449.1 - 1.3e-08 34.8 0.1 0.0075 16.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EIM85449.1 - 0.0001 22.2 0.3 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EIM85449.1 - 0.0011 18.7 0.1 0.49 10.2 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EIM85449.1 - 0.0013 18.8 0.5 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 EIM85449.1 - 0.0019 17.8 0.1 2.5 7.7 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EIM85449.1 - 0.0047 16.5 0.2 3.8 7.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 EIM85449.1 - 0.047 13.1 0.0 8.8 5.7 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.1 EIM85449.1 - 0.047 13.8 0.0 7.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Transposase DDE domain Redoxin PF08534.5 EIM85449.1 - 0.11 12.0 0.7 7.6 6.0 0.0 2.9 3 0 0 3 3 3 0 Redoxin Sec63 PF02889.11 EIM85451.1 - 1.1e-35 123.3 0.0 1.6e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EIM85451.1 - 1.5e-15 56.6 0.3 6e-15 54.7 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain PPR_2 PF13041.1 EIM85452.1 - 6.3e-50 166.9 1.1 2e-11 43.7 0.0 12.8 11 1 4 15 15 15 7 PPR repeat family PPR_1 PF12854.2 EIM85452.1 - 2.8e-37 125.8 0.1 1.8e-08 33.7 0.0 11.1 12 0 0 12 12 12 6 PPR repeat PPR PF01535.15 EIM85452.1 - 1.5e-35 118.6 8.1 1.1e-06 28.1 0.0 13.9 17 0 0 17 17 17 5 PPR repeat PPR_3 PF13812.1 EIM85452.1 - 1.3e-29 99.9 13.6 4.3e-06 26.5 0.0 14.4 16 0 0 16 16 16 5 Pentatricopeptide repeat domain TPR_14 PF13428.1 EIM85452.1 - 1e-11 44.3 12.1 3.8 8.4 0.0 11.3 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM85452.1 - 4.8e-09 36.4 6.6 0.41 11.0 0.0 8.6 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM85452.1 - 5.2e-05 22.7 0.3 16 5.5 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat ECSIT PF06239.6 EIM85452.1 - 0.00015 20.6 0.1 0.51 9.1 0.1 3.4 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EIM85452.1 - 0.0028 17.5 0.4 16 5.5 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat RPM2 PF08579.6 EIM85452.1 - 0.0029 17.7 0.0 0.31 11.1 0.0 3.0 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_8 PF13181.1 EIM85452.1 - 0.023 14.4 2.3 14 5.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat SH3_1 PF00018.23 EIM85453.1 - 4.1e-12 45.3 0.0 6.3e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM85453.1 - 4.1e-12 45.4 0.0 6.6e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM85453.1 - 3.7e-08 32.7 0.0 5.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PLRV_ORF5 PF01690.12 EIM85453.1 - 1.5 7.8 7.9 2.4 7.2 0.7 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein SOG2 PF10428.4 EIM85453.1 - 6.2 5.3 10.2 7.9 5.0 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_cc PF11790.3 EIM85454.1 - 8.8e-61 205.3 0.4 1e-60 205.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1996 PF09362.5 EIM85455.1 - 1.8e-71 240.5 0.4 2.3e-71 240.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Amidase PF01425.16 EIM85456.1 - 1.3e-69 235.1 0.0 7.2e-68 229.4 0.0 2.0 1 1 1 2 2 2 2 Amidase Mito_carr PF00153.22 EIM85458.1 - 3e-51 171.0 1.9 7.2e-19 67.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 EIM85459.1 - 2e-44 151.3 1.1 2.7e-44 150.8 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIM85459.1 - 5.7e-25 88.0 0.1 2.7e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIM85459.1 - 1e-20 72.9 0.3 2.4e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIM85459.1 - 2.8e-20 72.9 0.1 4.4e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EIM85459.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF2638 PF10937.3 EIM85460.1 - 8.8e-10 39.6 1.7 1.7e-08 35.4 1.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) RNA_pol_Rpb1_5 PF04998.12 EIM85461.1 - 5e-94 314.6 0.1 7.9e-94 313.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EIM85461.1 - 1.2e-92 310.7 0.0 1.8e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EIM85461.1 - 1.6e-67 226.6 0.0 3.2e-67 225.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIM85461.1 - 1.9e-36 125.1 0.0 6.7e-36 123.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EIM85461.1 - 8.4e-32 109.1 0.0 1.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EIM85461.1 - 0.0041 16.5 0.1 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 InsA N-terminal domain SLT_2 PF13406.1 EIM85461.1 - 0.21 10.4 0.0 0.44 9.3 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase SLT domain Proteasome PF00227.21 EIM85462.1 - 3.3e-44 150.4 0.2 1.8e-43 148.0 0.2 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM85462.1 - 3.5e-15 54.9 0.4 6.2e-15 54.2 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PC-Esterase PF13839.1 EIM85463.1 - 4.2e-05 23.4 0.0 0.00049 20.0 0.0 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GDI PF00996.13 EIM85464.1 - 3.8e-57 193.5 0.0 1e-56 192.1 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EIM85464.1 - 7.9e-05 22.6 0.2 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM85464.1 - 0.094 11.5 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase G-gamma PF00631.17 EIM85464.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 GGL domain RRM_1 PF00076.17 EIM85465.1 - 9.3e-42 140.5 0.0 7.4e-20 70.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85465.1 - 8.7e-32 108.9 0.0 4.5e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85465.1 - 2.1e-15 56.3 0.0 7.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM85465.1 - 0.073 12.8 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.13 EIM85466.1 - 6.6e-07 29.1 6.8 1.1e-06 28.4 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EIM85466.1 - 6.6 6.9 9.3 38 4.5 1.0 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ric8 PF10165.4 EIM85467.1 - 4.3e-62 210.3 0.0 4.6e-61 207.0 0.0 2.2 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn F-box-like PF12937.2 EIM85468.1 - 8.3e-08 31.8 0.0 1.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like PilX PF13681.1 EIM85468.1 - 0.038 14.4 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term LRR_4 PF12799.2 EIM85468.1 - 0.11 12.1 0.6 6.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Response_reg PF00072.19 EIM85470.1 - 2.2e-05 24.4 0.1 0.31 11.0 0.0 3.5 3 1 0 3 3 3 2 Response regulator receiver domain Glyco_hydro_42M PF08532.5 EIM85470.1 - 7.1e-05 22.0 0.0 1.9 7.5 0.0 4.1 4 0 0 4 4 4 2 Beta-galactosidase trimerisation domain Methyltransf_24 PF13578.1 EIM85470.1 - 0.012 16.4 4.7 6.6 7.6 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain DUF2367 PF10164.4 EIM85470.1 - 0.062 13.1 0.0 3 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) AAA_5 PF07728.9 EIM85470.1 - 0.096 12.4 0.0 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF1318 PF07027.7 EIM85470.1 - 0.26 11.5 0.9 53 4.1 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1318) Cyclin PF08613.6 EIM85471.1 - 3.2e-39 134.7 4.9 3.2e-39 134.7 3.4 2.4 2 1 0 2 2 2 1 Cyclin CDC27 PF09507.5 EIM85471.1 - 7.9 5.5 19.0 1.6 7.8 0.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.11 EIM85473.1 - 4.4e-20 71.6 39.6 1.1e-14 53.9 9.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M56 PF05569.6 EIM85473.1 - 0.046 12.6 1.4 0.1 11.5 0.1 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 WBP-1 PF11669.3 EIM85473.1 - 0.15 12.1 1.2 7.1 6.7 0.1 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 SieB PF14163.1 EIM85473.1 - 8.2 5.9 6.9 1.3 8.5 1.6 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Spt4 PF06093.8 EIM85475.1 - 3.1e-30 103.8 0.1 3.9e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.20 EIM85476.1 - 8.3e-12 44.9 0.0 4.4e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) PIGA PF08288.7 EIM85477.1 - 3.3e-38 129.9 0.2 8.8e-38 128.5 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EIM85477.1 - 2.4e-25 88.9 0.0 4.2e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIM85477.1 - 3.8e-16 59.3 0.3 6.2e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIM85477.1 - 5.2e-16 59.1 0.1 8.6e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EIM85477.1 - 6.1e-12 45.8 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIM85477.1 - 0.0036 17.5 0.0 0.0089 16.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2433 PF10360.4 EIM85478.1 - 3.5e-32 111.5 0.0 7.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.17 EIM85478.1 - 8.3e-07 28.5 0.1 1.6e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85478.1 - 1.1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.9 EIM85478.1 - 5.6 6.1 9.9 9.6 5.3 6.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NARP1 PF12569.3 EIM85478.1 - 8.3 5.0 9.8 12 4.5 6.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med13_C PF06333.7 EIM85479.1 - 3.4e-16 58.8 0.1 3.4e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal ATP-synt_S1 PF05827.7 EIM85480.1 - 2.8e-16 59.6 2.7 6.7e-15 55.1 1.8 2.0 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PRKCSH-like PF12999.2 EIM85482.1 - 5.4e-48 162.8 0.4 9.3e-48 162.1 0.3 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EIM85482.1 - 4.7e-26 91.1 0.3 1.1e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EIM85482.1 - 1.8e-10 41.4 1.2 5.4e-10 39.9 0.8 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EIM85482.1 - 0.021 14.7 11.1 0.7 9.8 0.5 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A IncA PF04156.9 EIM85482.1 - 0.91 9.0 12.7 2.9 7.4 4.3 3.1 2 1 1 3 3 3 0 IncA protein Erf4 PF10256.4 EIM85483.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Peptidase_M24 PF00557.19 EIM85484.1 - 2.9e-55 187.0 0.0 4.1e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIM85484.1 - 4.8e-34 116.6 0.0 1.2e-33 115.2 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain AA_permease_2 PF13520.1 EIM85485.1 - 1.3e-41 142.5 44.8 1.6e-41 142.2 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM85485.1 - 9.2e-23 80.3 38.4 1.1e-22 80.1 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 EIM85486.1 - 3.6e-05 23.3 0.4 0.00012 21.7 0.3 2.0 1 0 0 1 1 1 1 F-box-like Ribosomal_S25 PF03297.10 EIM85487.1 - 6.9e-42 141.7 0.7 7.6e-42 141.6 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EIM85487.1 - 0.058 13.1 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain GerPB PF10803.3 EIM85487.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Spore germination GerPB HTH_24 PF13412.1 EIM85487.1 - 0.13 11.6 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FGGY_C PF02782.11 EIM85488.1 - 5.9e-43 146.7 0.3 8.9e-43 146.2 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIM85488.1 - 4.5e-19 68.7 2.1 4.1e-17 62.3 0.0 3.0 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EIM85488.1 - 3.1e-05 23.4 0.5 0.003 16.8 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Geminin PF07412.7 EIM85488.1 - 0.037 13.6 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Geminin CmcH_NodU PF02543.10 EIM85488.1 - 0.13 11.3 0.1 0.27 10.3 0.1 1.4 1 1 0 1 1 1 0 Carbamoyltransferase Ribosomal_L2_C PF03947.13 EIM85489.1 - 1.4e-40 138.1 2.1 2.1e-40 137.5 1.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIM85489.1 - 6.3e-15 54.9 0.1 1.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_S9_N PF02897.10 EIM85490.1 - 4.9e-90 302.0 7.8 6.4e-90 301.6 5.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EIM85490.1 - 5.1e-56 189.2 0.0 1.1e-55 188.1 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIM85490.1 - 6.7e-05 22.5 0.5 0.0004 20.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mito_carr PF00153.22 EIM85491.1 - 2e-63 210.1 0.5 7.7e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 EIM85493.1 - 2.5e-28 99.0 0.1 3.9e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIM85493.1 - 2.2e-19 68.7 0.9 4.8e-19 67.6 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIM85493.1 - 3.3e-17 62.0 0.0 8.4e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EIM85493.1 - 5.9e-13 49.3 0.0 1.8e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIM85493.1 - 0.00081 19.6 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain F-box-like PF12937.2 EIM85494.1 - 4.1e-08 32.8 0.2 8.1e-08 31.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM85494.1 - 5.2e-06 25.9 0.3 1.2e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain Corona_NS1 PF06145.6 EIM85494.1 - 0.16 11.3 0.4 0.29 10.4 0.3 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 MIF4G_like PF09088.6 EIM85495.1 - 3.4e-62 209.2 0.0 1.1e-61 207.5 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EIM85495.1 - 4.2e-34 117.9 0.0 1.4e-33 116.1 0.0 1.8 1 1 0 1 1 1 1 MIF4G like UAA PF08449.6 EIM85496.1 - 6.3e-63 212.4 21.5 1.6e-32 112.6 0.3 4.4 4 1 1 5 5 5 4 UAA transporter family Colicin_V PF02674.11 EIM85496.1 - 0.024 14.5 11.8 3.3 7.5 0.2 3.7 2 1 1 3 3 3 0 Colicin V production protein TPT PF03151.11 EIM85496.1 - 0.029 14.0 0.5 0.029 14.0 0.3 2.9 2 1 1 3 3 3 0 Triose-phosphate Transporter family DUF2611 PF11022.3 EIM85496.1 - 1.8 8.6 3.8 2.3 8.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) Cyclin_N PF00134.18 EIM85497.1 - 3.9e-15 55.5 0.0 4.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIM85497.1 - 1e-13 51.9 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin dCMP_cyt_deam_1 PF00383.17 EIM85498.1 - 3.8e-22 77.8 0.1 5.4e-22 77.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EIM85498.1 - 6.6e-05 22.7 1.0 0.0036 17.1 0.7 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase PPR_2 PF13041.1 EIM85499.1 - 1.7e-10 40.7 0.0 0.00031 20.6 0.0 5.5 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EIM85499.1 - 1e-05 25.3 7.5 20 5.8 0.1 7.5 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EIM85499.1 - 0.033 14.1 3.1 14 5.8 0.0 5.6 7 0 0 7 7 7 0 PPR repeat URO-D PF01208.12 EIM85500.1 - 2.3e-125 418.0 0.0 2.6e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SH3_1 PF00018.23 EIM85501.1 - 2.7e-20 71.4 0.0 3.6e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIM85501.1 - 1.2e-18 66.3 0.0 2.4e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EIM85501.1 - 2.1e-12 46.3 0.0 5.7e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EIM85501.1 - 5.2e-06 26.2 0.2 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EIM85501.1 - 0.0028 17.2 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Retrotrans_gag PF03732.12 EIM85501.1 - 0.069 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2217 PF10265.4 EIM85501.1 - 1.8 7.2 4.1 2.8 6.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 EIM85501.1 - 2.3 6.3 6.4 3.3 5.8 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Not3 PF04065.10 EIM85502.1 - 1.3e-89 299.5 22.1 1.9e-89 298.9 15.3 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIM85502.1 - 3e-43 146.9 6.0 3e-43 146.9 4.2 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family RVT_1 PF00078.22 EIM85503.1 - 4.6e-05 22.8 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2881 PF11087.3 EIM85504.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) GTP_EFTU PF00009.22 EIM85505.1 - 9e-33 113.2 0.0 9e-33 113.2 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIM85505.1 - 1.7e-17 63.2 0.0 4.9e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIM85505.1 - 1.6e-13 50.5 8.2 1.3e-10 41.2 0.1 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM85505.1 - 2.1e-06 27.6 0.0 6.2e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIM85505.1 - 0.0049 17.0 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 EIM85505.1 - 0.0085 15.4 0.0 0.047 13.0 0.0 2.4 2 1 0 2 2 2 1 Ras family ATP_bind_1 PF03029.12 EIM85505.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FHIPEP PF00771.15 EIM85505.1 - 2.1 6.5 4.9 5.3 5.2 3.4 1.6 1 0 0 1 1 1 0 FHIPEP family Arf PF00025.16 EIM85506.1 - 1.5e-68 229.4 0.5 1.8e-68 229.2 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIM85506.1 - 2e-13 49.7 2.3 7.4e-08 31.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIM85506.1 - 2.1e-09 36.8 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIM85506.1 - 8.1e-08 31.6 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIM85506.1 - 1.1e-07 31.3 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EIM85506.1 - 3.1e-07 30.3 0.0 4.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM85506.1 - 1.8e-05 24.2 0.0 0.00068 19.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM85506.1 - 1.9e-05 25.1 0.0 3.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIM85506.1 - 0.019 14.8 0.0 0.073 12.8 0.0 1.9 1 1 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EIM85506.1 - 0.021 14.2 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EIM85506.1 - 0.12 11.1 0.2 0.74 8.5 0.0 2.2 3 0 0 3 3 3 0 ArgK protein CMAS PF02353.15 EIM85508.1 - 5.8e-59 199.4 0.0 7.9e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EIM85508.1 - 8e-10 39.2 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM85508.1 - 1.1e-09 38.1 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM85508.1 - 3.5e-06 27.4 0.0 9.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM85508.1 - 9.9e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM85508.1 - 0.001 19.4 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM85508.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM85508.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.5 EIM85508.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EIM85508.1 - 0.0027 18.5 0.0 0.021 15.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EIM85508.1 - 0.027 13.5 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EIM85508.1 - 0.036 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FA_desaturase PF00487.19 EIM85509.1 - 4.4e-13 49.2 23.7 6.9e-13 48.6 16.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIM85509.1 - 2.2e-11 43.4 0.0 3.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF340 PF03956.8 EIM85509.1 - 0.031 13.5 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Membrane protein of unknown function (DUF340) Kinesin PF00225.18 EIM85510.1 - 4.7e-108 360.8 0.0 7.6e-108 360.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EIM85510.1 - 1.5e-39 134.8 0.3 3.1e-39 133.8 0.2 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EIM85510.1 - 1.3e-10 41.4 0.1 5.3e-10 39.4 0.0 2.1 1 0 0 1 1 1 1 PH domain FHA PF00498.21 EIM85510.1 - 2.2e-08 34.0 0.1 1.3e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 EIM85510.1 - 0.0076 16.2 0.1 0.022 14.7 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B DUF3037 PF11236.3 EIM85510.1 - 0.18 11.8 1.4 0.69 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Med26 PF08711.6 EIM85511.1 - 6.5e-07 28.7 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LIM_bind PF01803.11 EIM85512.1 - 2.8e-35 121.5 0.0 3.3e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein Ribosomal_S4 PF00163.14 EIM85513.1 - 1.1e-14 54.5 0.8 1.5e-14 54.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIM85513.1 - 3.8e-11 42.2 0.0 6.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Herpes_LAMP2 PF06126.6 EIM85513.1 - 0.041 12.2 0.0 0.051 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 COG2 PF06148.6 EIM85513.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 E_Pc_C PF06752.7 EIM85516.1 - 0.13 11.7 1.3 0.17 11.3 0.9 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DSPn PF14671.1 EIM85517.1 - 1.7e-38 131.7 0.0 2e-36 125.0 0.0 2.8 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EIM85517.1 - 1.9e-16 59.8 0.0 3.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM85517.1 - 1.3e-05 24.6 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIM85517.1 - 0.00048 20.1 0.0 0.00065 19.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF2454 PF10521.4 EIM85518.1 - 1.5e-29 102.9 0.0 2.1e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) p450 PF00067.17 EIM85519.1 - 1.7e-67 227.9 0.0 7.2e-67 225.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM85520.1 - 1.7e-69 234.5 0.0 3.9e-69 233.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM85521.1 - 1.8e-84 283.9 0.0 2.2e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EIM85521.1 - 6e-35 120.6 0.0 1.3e-34 119.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EIM85521.1 - 1.2e-23 83.6 0.0 2.6e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIM85521.1 - 5.5e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EIM85521.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 EIM85521.1 - 0.0096 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain SNF2_N PF00176.18 EIM85522.1 - 9.9e-59 198.5 0.1 1.5e-58 197.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM85522.1 - 2.3e-10 40.2 0.0 5.6e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM85522.1 - 4.8e-05 23.2 2.0 5.8e-05 22.9 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EIM85522.1 - 5.3e-05 22.9 5.4 5.3e-05 22.9 3.7 2.1 2 0 0 2 2 1 1 Ring finger domain DEAD PF00270.24 EIM85522.1 - 7.4e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EIM85522.1 - 8.3e-05 22.1 4.3 8.3e-05 22.1 3.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM85522.1 - 0.00055 19.8 4.0 0.00055 19.8 2.8 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85522.1 - 0.0012 18.5 3.8 0.0012 18.5 2.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIM85522.1 - 0.0059 16.1 3.0 0.014 14.8 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EIM85522.1 - 0.035 13.8 1.6 0.18 11.6 1.1 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein HABP4_PAI-RBP1 PF04774.10 EIM85522.1 - 5.4 7.5 8.8 2.1 8.8 4.1 1.9 2 0 0 2 2 1 0 Hyaluronan / mRNA binding family WW PF00397.21 EIM85523.1 - 0.00081 19.1 10.1 0.0088 15.8 7.0 2.3 1 1 0 1 1 1 1 WW domain HMG_box PF00505.14 EIM85524.1 - 4.1e-16 58.9 1.7 1.1e-15 57.6 1.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM85524.1 - 4.3e-11 43.0 1.6 1e-10 41.7 1.1 1.7 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 EIM85525.1 - 8e-09 35.0 0.1 2.8e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM85525.1 - 0.002 17.8 0.1 10 5.9 0.2 4.6 3 1 1 4 4 4 2 Leucine rich repeat Ribosomal_L44 PF00935.14 EIM85526.1 - 0.49 10.4 5.7 0.44 10.5 0.3 2.8 2 0 0 2 2 2 0 Ribosomal protein L44 NDUFA12 PF05071.11 EIM85527.1 - 1.3e-25 89.8 1.2 1.8e-25 89.4 0.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.19 EIM85528.1 - 2e-30 105.9 0.0 3.7e-29 101.7 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase p450 PF00067.17 EIM85529.1 - 9.4e-65 218.9 0.0 1.1e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM85531.1 - 6.2e-68 229.3 0.0 7.5e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trs65 PF12735.2 EIM85532.1 - 3.6e-23 82.3 0.0 3.6e-23 82.3 0.0 4.4 5 1 0 5 5 5 1 TRAPP trafficking subunit Trs65 Internalin_N PF12354.3 EIM85532.1 - 0.073 12.6 0.9 0.16 11.5 0.6 1.6 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Glyco_transf_7N PF13733.1 EIM85535.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Ribosomal_L12 PF00542.14 EIM85536.1 - 4e-19 68.3 6.1 3.2e-18 65.4 2.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CDC37_C PF08564.5 EIM85536.1 - 0.052 13.3 1.9 0.17 11.7 0.1 2.2 1 1 1 2 2 2 0 Cdc37 C terminal domain Ribosomal_60s PF00428.14 EIM85536.1 - 0.62 10.5 10.2 0.29 11.5 4.9 2.1 1 1 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S7e PF01251.13 EIM85537.1 - 9.5e-85 282.8 4.8 1.7e-84 282.0 3.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 EIM85537.1 - 4e-18 64.8 2.7 2.1e-14 52.8 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIM85537.1 - 6.5e-11 41.3 2.8 0.0033 16.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM85537.1 - 3.6e-07 29.5 2.9 0.23 11.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM85537.1 - 0.0013 19.3 2.8 0.069 13.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM85537.1 - 0.0031 17.5 1.1 0.029 14.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM85537.1 - 0.047 14.0 3.0 0.084 13.2 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM85537.1 - 0.11 12.6 0.7 0.26 11.4 0.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIM85537.1 - 0.13 12.1 1.0 8.1 6.4 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.17 EIM85538.1 - 4.3e-46 156.2 0.1 4.9e-43 146.3 0.1 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EIM85538.1 - 2.5e-21 76.3 0.2 7.9e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM85538.1 - 2.1e-11 43.3 0.1 3.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIM85538.1 - 1.5e-06 28.1 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIM85538.1 - 6e-05 22.2 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIM85538.1 - 0.00066 18.9 0.1 0.0026 17.0 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIM85538.1 - 0.0009 18.7 0.1 0.0082 15.6 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EIM85538.1 - 0.0019 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIM85538.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EIM85538.1 - 0.0084 16.0 0.1 0.026 14.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIM85538.1 - 0.021 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIM85538.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 EIM85538.1 - 0.031 14.2 0.2 0.1 12.5 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EIM85538.1 - 0.036 13.0 0.2 0.21 10.5 0.1 2.0 2 0 0 2 2 2 0 Septin cobW PF02492.14 EIM85538.1 - 0.15 11.5 0.3 0.5 9.7 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L3 PF00297.17 EIM85540.1 - 2.6e-120 400.7 7.7 3.1e-120 400.4 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.1 EIM85541.1 - 1.4e-09 37.7 1.9 2.4 8.1 0.0 6.7 5 1 2 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EIM85541.1 - 3.4e-08 33.1 6.9 0.49 10.8 0.0 6.6 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 EIM85541.1 - 5.8e-07 29.0 3.4 0.11 12.5 0.1 6.2 6 1 1 7 7 7 1 PPR repeat PPR_1 PF12854.2 EIM85541.1 - 0.0063 15.9 4.5 0.18 11.3 0.1 3.8 4 0 0 4 4 4 1 PPR repeat Apc15p PF05841.6 EIM85541.1 - 0.11 13.2 3.2 0.18 12.5 0.4 2.5 2 0 0 2 2 2 0 Apc15p protein Pex2_Pex12 PF04757.9 EIM85544.1 - 2.7e-19 69.5 3.1 3.7e-19 69.0 1.2 1.7 1 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIM85544.1 - 1.2e-07 31.6 1.1 1.8e-07 31.0 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85544.1 - 1.4e-06 27.8 0.3 2.2e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM85544.1 - 2.3e-06 27.3 0.3 3.5e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIM85544.1 - 0.00076 19.3 2.2 0.0013 18.5 1.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIM85544.1 - 0.0084 15.7 0.5 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 EIM85544.1 - 0.27 11.0 3.6 0.46 10.2 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-RING_5 PF14634.1 EIM85544.1 - 0.32 10.7 3.2 6.7 6.5 2.9 2.1 1 1 1 2 2 2 0 zinc-RING finger domain His_Phos_2 PF00328.17 EIM85545.1 - 6.4e-53 180.2 0.0 7.5e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AMMECR1 PF01871.12 EIM85546.1 - 1.6e-38 131.4 0.0 1e-26 93.0 0.0 2.0 2 0 0 2 2 2 2 AMMECR1 MRC1 PF09444.5 EIM85548.1 - 6.4e-16 58.9 17.4 6.4e-16 58.9 12.0 6.4 5 1 1 6 6 6 1 MRC1-like domain Ank_2 PF12796.2 EIM85549.1 - 4e-41 139.2 0.2 5.9e-14 52.1 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIM85549.1 - 1.7e-36 122.1 10.8 2.3e-07 30.2 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EIM85549.1 - 2.6e-30 104.2 6.3 7e-09 35.9 0.3 5.4 4 1 2 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.14 EIM85549.1 - 5.8e-30 105.0 5.7 2.1e-15 57.2 0.3 3.1 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 EIM85549.1 - 2.7e-26 89.0 6.0 5.2e-05 23.0 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EIM85549.1 - 5.8e-25 86.7 12.1 7.6e-09 35.5 0.1 7.8 3 2 5 8 8 8 6 Ankyrin repeats (many copies) GDPD PF03009.12 EIM85549.1 - 3.6e-15 56.1 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.22 EIM85550.1 - 1.7e-20 73.7 0.0 3.9e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM85550.1 - 5.8e-12 46.1 0.0 3.6e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIM85550.1 - 6.8e-05 22.7 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EIM85550.1 - 9.1e-05 21.7 0.0 0.0036 16.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EIM85550.1 - 0.00017 20.7 0.0 0.034 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 EIM85550.1 - 0.00035 19.1 0.0 0.043 12.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM85550.1 - 0.0011 19.1 0.1 0.58 10.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIM85550.1 - 0.0016 17.9 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM85550.1 - 0.014 15.3 0.2 0.088 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EIM85550.1 - 0.032 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIM85550.1 - 0.046 14.5 0.0 0.087 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM85550.1 - 0.056 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EIM85550.1 - 0.075 12.6 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EIM85550.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIM85550.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EIM85550.1 - 0.2 11.9 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIM85550.1 - 0.21 11.8 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1_like PF12832.2 EIM85550.1 - 2.6 7.9 5.6 0.76 9.6 1.4 1.9 2 0 0 2 2 2 0 MFS_1 like family GTP_cyclohydroI PF01227.17 EIM85551.1 - 1.9e-75 252.1 0.5 2.1e-75 251.9 0.4 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EIM85551.1 - 0.00023 21.0 0.0 0.00082 19.2 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 EIM85551.1 - 0.012 15.4 0.1 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tho2 PF11262.3 EIM85552.1 - 6.2e-66 222.4 0.0 8.4e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EIM85552.1 - 4.8e-24 83.9 0.0 1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Exonuc_X-T_C PF08411.5 EIM85554.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal AAA_25 PF13481.1 EIM85556.1 - 0.018 14.4 0.1 0.083 12.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain Stimulus_sens_1 PF13756.1 EIM85556.1 - 0.23 11.8 1.9 0.94 9.8 0.1 2.8 3 0 0 3 3 3 0 Stimulus-sensing domain Pex2_Pex12 PF04757.9 EIM85557.1 - 8e-51 172.6 6.7 1e-50 172.2 4.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIM85557.1 - 2.6e-07 30.5 0.7 4.1e-07 29.9 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85557.1 - 2.5e-06 27.0 0.3 3.9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM85557.1 - 6.8e-06 25.8 0.2 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIM85557.1 - 0.0016 18.2 2.0 0.0027 17.5 1.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIM85557.1 - 0.02 14.5 0.3 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 EIM85557.1 - 0.11 12.1 3.0 0.22 11.3 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-RING_5 PF14634.1 EIM85557.1 - 0.7 9.6 3.0 13 5.6 2.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.9 EIM85557.1 - 0.9 9.0 2.8 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif SSB PF00436.20 EIM85559.1 - 7.5e-17 61.0 0.0 9e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HBS1_N PF08938.5 EIM85560.1 - 1.5e-13 50.6 0.1 3.7e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.22 EIM85561.1 - 6.5e-35 120.2 0.0 8.3e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIM85561.1 - 1e-08 35.2 0.0 7.8e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIM85561.1 - 8e-07 29.0 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIM85561.1 - 0.00026 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 adh_short PF00106.20 EIM85563.1 - 8.2e-28 97.4 0.7 1.3e-27 96.7 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM85563.1 - 4.6e-27 95.3 0.1 5.4e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM85563.1 - 1e-08 35.0 0.6 2.2e-08 33.9 0.4 1.5 1 1 0 1 1 1 1 KR domain Herpes_U44 PF04533.8 EIM85563.1 - 0.021 14.0 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Herpes virus U44 protein NTP_transferase PF00483.18 EIM85563.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase Pkinase PF00069.20 EIM85564.1 - 4.1e-13 49.0 0.0 5.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM85564.1 - 7.3e-07 29.1 0.1 1.5e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIM85564.1 - 8.5e-06 25.0 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM85564.1 - 2.2e-05 23.6 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIM85564.1 - 0.00045 19.2 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM85564.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EIM85564.1 - 0.068 11.9 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Phasin_2 PF09361.5 EIM85565.1 - 0.072 13.1 0.6 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Phasin protein EF-hand_1 PF00036.27 EIM85567.1 - 6.7e-26 87.5 12.8 2.4e-07 29.5 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIM85567.1 - 1.3e-24 86.1 3.6 2.8e-12 46.5 0.9 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIM85567.1 - 1.2e-19 68.3 7.2 3.3e-05 23.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIM85567.1 - 3.7e-19 67.1 12.3 2.9e-06 26.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIM85567.1 - 1.1e-14 53.7 13.4 7.3e-05 22.3 1.0 4.6 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIM85567.1 - 4.4e-06 26.6 0.0 0.0047 16.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIM85567.1 - 0.0002 21.0 7.0 0.0096 15.6 0.7 3.5 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand RST PF12174.3 EIM85567.1 - 0.12 12.2 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain TrmE_N PF10396.4 EIM85568.1 - 3.1e-34 117.3 0.0 7.6e-32 109.6 0.0 2.5 1 1 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EIM85568.1 - 3.4e-18 65.8 0.0 9.1e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EIM85568.1 - 4.5e-17 62.0 0.0 8.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM85568.1 - 3.5e-05 23.7 0.0 0.00018 21.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EIM85568.1 - 0.00064 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIM85568.1 - 0.00075 19.9 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EIM85568.1 - 0.007 17.1 0.1 0.022 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIM85568.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM85568.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EIM85568.1 - 0.045 12.9 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF362 PF04015.7 EIM85568.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) MARVEL PF01284.18 EIM85569.1 - 1.5e-08 34.6 16.5 1.5e-08 34.6 11.4 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF962 PF06127.6 EIM85569.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF1634 PF07843.6 EIM85569.1 - 6.5 6.4 13.9 8.2 6.1 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) WD40 PF00400.27 EIM85570.1 - 8e-06 25.5 0.8 1.7e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Pex2_Pex12 PF04757.9 EIM85571.1 - 2.9e-37 128.2 5.0 3.8e-37 127.9 3.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIM85571.1 - 2e-07 30.8 0.7 3.2e-07 30.2 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85571.1 - 2e-06 27.3 0.3 3e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM85571.1 - 5.3e-06 26.1 0.2 8.4e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIM85571.1 - 0.0012 18.6 2.0 0.0021 17.8 1.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIM85571.1 - 0.016 14.8 0.3 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 EIM85571.1 - 0.088 12.5 3.0 0.17 11.6 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-RING_5 PF14634.1 EIM85571.1 - 0.52 10.0 3.1 11 5.8 2.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.9 EIM85571.1 - 0.62 9.5 2.8 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif AAA_25 PF13481.1 EIM85572.1 - 0.026 13.9 0.1 0.099 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cas_Csd1 PF09709.5 EIM85575.1 - 0.03 12.6 0.0 0.031 12.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) WD40 PF00400.27 EIM85576.1 - 8.5e-16 57.1 9.8 9.1e-06 25.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4199 PF13858.1 EIM85578.1 - 0.62 9.9 8.8 1.5 8.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MARVEL PF01284.18 EIM85579.1 - 4.7e-07 29.7 5.7 8.7e-07 28.8 3.9 1.4 1 0 0 1 1 1 1 Membrane-associating domain MBOAT PF03062.14 EIM85580.1 - 4.9e-43 147.4 4.1 4.9e-43 147.4 2.8 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.6 EIM85580.1 - 0.038 13.9 0.1 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Ribosomal_L18e PF00828.14 EIM85581.1 - 4.8e-23 81.9 0.0 4.8e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 EIM85582.1 - 8.2e-18 63.8 0.0 1.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85582.1 - 6e-16 58.0 0.0 8.7e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85582.1 - 2.4e-15 56.2 0.0 3.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_28 PF00295.12 EIM85583.1 - 7.8e-58 195.9 23.4 9.8e-58 195.6 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM85583.1 - 2.6e-05 24.0 27.2 2.6e-05 24.0 18.9 2.9 2 1 1 3 3 3 1 Right handed beta helix region ACBP PF00887.14 EIM85584.1 - 6.3e-18 64.2 0.1 9.6e-18 63.6 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein SlyX PF04102.7 EIM85584.1 - 0.14 12.5 2.3 21 5.5 0.0 2.5 2 0 0 2 2 2 0 SlyX Ank PF00023.25 EIM85587.1 - 5.6e-20 70.0 0.2 4.2e-09 35.7 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EIM85587.1 - 6.9e-20 71.1 0.5 8.5e-10 38.8 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM85587.1 - 2.3e-16 59.4 0.1 1.3e-06 28.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM85587.1 - 2.5e-15 56.4 0.6 6.1e-10 39.3 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM85587.1 - 4.5e-15 54.2 2.3 8.8e-06 25.4 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat KilA-N PF04383.8 EIM85587.1 - 0.00033 20.2 0.0 0.0033 17.0 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Reo_sigmaC PF04582.7 EIM85587.1 - 0.11 11.7 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EIM85587.1 - 0.67 9.7 2.4 1.6 8.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EIM85587.1 - 1.5 8.5 5.3 1.5 8.6 2.7 1.7 2 0 0 2 2 2 0 Laminin Domain II WD40 PF00400.27 EIM85588.1 - 2.9e-20 71.3 15.6 2.9e-07 30.1 1.7 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIM85588.1 - 0.00029 20.6 0.2 0.54 9.9 0.1 3.5 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EIM85588.1 - 0.0067 14.3 0.0 0.11 10.2 0.0 2.2 1 1 0 2 2 2 2 IKI3 family DUF106 PF01956.11 EIM85589.1 - 0.14 11.6 2.6 0.18 11.3 1.8 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DEAD PF00270.24 EIM85590.1 - 2.9e-36 124.5 0.0 1.2e-35 122.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM85590.1 - 3.2e-21 74.9 0.2 7.8e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EIM85590.1 - 2.8e-19 68.6 3.1 2.8e-19 68.6 2.2 2.8 2 0 0 2 2 2 1 DBP10CT (NUC160) domain DUF3825 PF12873.2 EIM85590.1 - 0.15 11.1 0.1 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Nucleoside_tran PF01733.13 EIM85591.1 - 7.8e-38 130.3 6.1 3.3e-35 121.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoside transporter Glu-tRNAGln PF02686.10 EIM85592.1 - 0.0022 17.7 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Glu-tRNAGln amidotransferase C subunit Peptidase_M43 PF05572.8 EIM85593.1 - 3.5e-18 65.6 0.2 6e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EIM85593.1 - 2.3e-07 30.9 0.6 3.3e-07 30.4 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EIM85593.1 - 4.3e-07 30.1 0.4 6.1e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIM85593.1 - 1.7e-06 28.5 0.4 3.1e-06 27.7 0.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EIM85593.1 - 5e-05 22.7 1.8 8.3e-05 22.0 1.2 1.3 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 EIM85593.1 - 0.001 18.7 0.9 0.0023 17.6 0.6 1.7 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 EIM85593.1 - 0.0081 15.7 6.2 0.019 14.4 4.3 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EIM85593.1 - 0.022 13.6 0.4 0.032 13.0 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Vfa1 PF08432.5 EIM85594.1 - 5.4e-34 117.7 0.0 6e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 XRCC4 PF06632.7 EIM85594.1 - 0.13 11.0 3.2 0.17 10.6 2.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Apc15p PF05841.6 EIM85594.1 - 0.33 11.6 2.3 0.5 11.1 1.6 1.2 1 0 0 1 1 1 0 Apc15p protein ADH_N PF08240.7 EIM85595.1 - 4.8e-26 90.6 2.8 1e-25 89.5 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM85595.1 - 1.3e-18 66.8 0.1 2.5e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM85595.1 - 0.00028 20.0 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dUTPase PF00692.14 EIM85596.1 - 8.9e-40 135.1 0.0 1e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF4449 PF14613.1 EIM85598.1 - 1.3e-28 99.9 0.2 1.3e-28 99.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) PSD4 PF07631.6 EIM85598.1 - 0.096 13.0 0.9 0.22 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Peptidase_S10 PF00450.17 EIM85599.1 - 6.8e-83 279.1 0.1 9.2e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase zf-U1 PF06220.7 EIM85600.1 - 2.8e-20 71.5 5.4 3.8e-20 71.1 3.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EIM85600.1 - 0.0013 18.8 2.6 0.0023 18.0 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding CLPTM1 PF05602.7 EIM85601.1 - 1.7e-133 445.6 0.0 2.1e-133 445.2 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EIM85601.1 - 0.00076 18.9 0.4 0.0019 17.7 0.3 1.7 1 0 0 1 1 1 1 PQ loop repeat 2TM PF13239.1 EIM85601.1 - 0.12 12.4 2.3 0.13 12.3 0.3 2.1 2 0 0 2 2 2 0 2TM domain DUF788 PF05620.6 EIM85601.1 - 1.6 8.5 8.2 6.7 6.5 0.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF788) COesterase PF00135.23 EIM85602.1 - 4.4e-109 365.6 0.3 7.5e-109 364.8 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM85602.1 - 0.00052 19.6 0.8 0.0046 16.5 0.5 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM85602.1 - 0.0021 17.8 0.3 0.0054 16.4 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CytochromB561_N PF09786.4 EIM85603.1 - 0.4 9.0 16.0 0.75 8.1 11.1 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal MAS20 PF02064.10 EIM85604.1 - 2.7e-17 62.7 0.6 1.4e-16 60.5 0.4 2.1 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 EIM85604.1 - 5.6e-08 33.2 0.0 2.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 SET domain Ecl1 PF12855.2 EIM85604.1 - 2.1 7.7 7.4 0.88 8.9 3.1 1.9 2 0 0 2 2 2 0 Life-span regulatory factor AAA PF00004.24 EIM85605.1 - 6.9e-20 71.5 0.0 1.5e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM85605.1 - 0.0015 18.6 0.4 0.22 11.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 EIM85605.1 - 0.1 11.2 0.1 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GN3L_Grn1 PF08701.6 EIM85608.1 - 1.2e-21 76.4 18.8 4.9e-21 74.4 13.1 2.1 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EIM85608.1 - 7.1e-13 48.5 0.1 2.5e-10 40.3 0.0 2.7 3 0 0 3 3 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM85608.1 - 3e-06 27.1 7.7 0.00035 20.4 0.4 3.8 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 EIM85608.1 - 9.3e-05 21.6 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EIM85608.1 - 0.00012 21.5 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM85608.1 - 0.0012 19.3 0.0 0.026 14.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 EIM85608.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.13 EIM85608.1 - 0.0052 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EIM85608.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EIM85608.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIM85608.1 - 0.056 12.7 0.1 0.27 10.4 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF463 PF04317.7 EIM85608.1 - 0.12 10.9 0.1 0.2 10.1 0.1 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 HORMA PF02301.13 EIM85610.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 HORMA domain HIG_1_N PF04588.8 EIM85612.1 - 0.00021 20.9 2.5 0.00053 19.6 1.7 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2162 PF09930.4 EIM85612.1 - 0.035 13.2 0.1 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Bax1-I PF01027.15 EIM85612.1 - 0.072 12.6 0.1 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 UQ_con PF00179.21 EIM85613.1 - 5.7e-17 61.4 0.1 8.6e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIM85613.1 - 0.082 12.8 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain MliC PF09864.4 EIM85614.1 - 0.035 13.8 2.2 0.036 13.7 0.0 2.1 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme CDK2AP PF09806.4 EIM85614.1 - 2.4 8.3 9.9 0.28 11.3 3.3 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein WD40 PF00400.27 EIM85615.1 - 3e-80 261.5 31.2 1.1e-14 53.6 0.1 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EIM85615.1 - 8.9e-12 44.9 14.6 1.6e-07 31.0 4.7 2.5 1 1 1 2 2 2 2 PQQ-like domain NACHT PF05729.7 EIM85615.1 - 3.7e-10 39.7 0.0 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 1 1 NACHT domain Nup160 PF11715.3 EIM85615.1 - 3.7e-09 35.2 9.6 0.086 10.9 0.0 5.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIM85615.1 - 1.1e-07 31.7 0.1 0.029 14.0 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIM85615.1 - 2e-06 26.3 8.8 0.0029 15.9 0.1 4.2 1 1 4 5 5 5 4 Cytochrome D1 heme domain AAA_16 PF13191.1 EIM85615.1 - 6.6e-06 26.2 1.1 2.3e-05 24.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Me-amine-dh_H PF06433.6 EIM85615.1 - 1.2e-05 24.1 0.1 0.16 10.6 0.0 3.4 2 1 1 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.1 EIM85615.1 - 0.00073 19.7 11.4 5.6 7.3 0.0 6.5 5 1 1 6 6 6 1 PQQ-like domain RNA_helicase PF00910.17 EIM85615.1 - 0.014 15.5 0.1 0.16 12.1 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.1 EIM85615.1 - 0.021 14.9 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain PD40 PF07676.7 EIM85615.1 - 0.043 13.4 0.0 56 3.5 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 EIM85615.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EIM85615.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EIM85615.1 - 0.09 12.9 0.0 0.4 10.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIM85615.1 - 0.098 12.0 0.1 0.56 9.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain PLD_C PF12357.3 EIM85615.1 - 0.12 11.8 0.3 19 4.8 0.0 4.2 5 0 0 5 5 5 0 Phospholipase D C terminal RRM_1 PF00076.17 EIM85616.1 - 4e-17 61.6 0.1 1.2e-08 34.4 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85616.1 - 1.1e-14 54.0 0.1 7.5e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85616.1 - 1.7e-07 31.1 0.0 0.00042 20.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EIM85616.1 - 0.031 12.7 1.2 0.034 12.6 0.9 1.1 1 0 0 1 1 1 0 Daxx Family TRAM_LAG1_CLN8 PF03798.11 EIM85617.1 - 9.4e-40 136.2 19.8 1.3e-39 135.8 13.8 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EIM85617.1 - 5.1e-08 32.2 0.4 1.7e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein RRM_6 PF14259.1 EIM85618.1 - 1.1e-22 79.7 0.1 3.6e-13 49.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM85618.1 - 7.9e-19 67.0 0.3 5.6e-11 41.9 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85618.1 - 4.5e-07 29.6 0.1 0.002 17.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sporozoite_P67 PF05642.6 EIM85618.1 - 0.35 8.6 22.0 0.043 11.6 11.7 1.9 1 1 0 2 2 2 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 EIM85618.1 - 3.4 7.9 11.8 8.7 6.6 8.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.8 EIM85618.1 - 7.7 6.0 17.8 0.37 10.3 8.3 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Nucleo_P87 PF07267.6 EIM85618.1 - 8.2 4.9 9.3 12 4.4 6.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EIM85618.1 - 9.6 4.1 10.0 15 3.4 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Amino_oxidase PF01593.19 EIM85619.1 - 1.7e-37 129.6 0.0 3.4e-37 128.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIM85619.1 - 2.6e-07 30.5 0.0 7.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EIM85620.1 - 4e-39 134.3 38.3 4e-39 134.3 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM85620.1 - 5.8e-11 41.2 1.9 8.9e-11 40.6 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EIM85621.1 - 1.1e-52 179.1 0.0 2.4e-52 178.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.17 EIM85622.1 - 1.4e-75 254.7 0.0 1.9e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIM85622.1 - 2.4e-07 30.4 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.15 EIM85623.1 - 5.3e-49 166.3 0.0 2e-48 164.4 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIM85623.1 - 1.8e-45 155.9 0.5 3.2e-45 155.2 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIM85623.1 - 1.2e-42 143.8 2.9 2.1e-13 50.2 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EIM85623.1 - 2.4e-19 70.2 0.0 6.2e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.16 EIM85623.1 - 0.00096 18.8 0.0 0.096 12.3 0.0 3.2 4 0 0 4 4 4 1 AhpC/TSA family Hydrolase_3 PF08282.7 EIM85623.1 - 0.0019 17.8 0.1 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 EIM85623.1 - 0.0045 16.8 0.4 11 6.0 0.0 4.0 4 0 0 4 4 4 1 Glutathione-dependent formaldehyde-activating enzyme MafB19-deam PF14437.1 EIM85623.1 - 0.054 13.1 0.2 56 3.3 0.0 3.4 3 0 0 3 3 3 0 MafB19-like deaminase Toxin-deaminase PF14424.1 EIM85623.1 - 0.057 13.4 0.7 21 5.1 0.0 3.4 4 0 0 4 4 4 0 The BURPS668_1122 family of deaminases ACT_6 PF13740.1 EIM85623.1 - 0.99 9.1 4.0 18 5.1 0.1 3.5 3 0 0 3 3 3 0 ACT domain Spc97_Spc98 PF04130.8 EIM85624.1 - 4e-109 365.3 0.0 5.3e-109 364.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family AMP-binding PF00501.23 EIM85625.1 - 2.5e-82 276.5 0.0 3.2e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM85625.1 - 9.8e-10 39.2 1.7 1.9e-09 38.3 1.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.10 EIM85626.1 - 2.7e-39 134.1 0.7 2.7e-39 134.1 0.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EIM85626.1 - 2.4e-37 128.5 0.0 2.4e-37 128.5 0.0 2.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EIM85626.1 - 1.4e-17 61.5 71.8 0.0042 16.6 0.5 14.0 13 0 0 13 13 13 11 IQ calmodulin-binding motif CH PF00307.26 EIM85626.1 - 1.5e-08 34.6 0.0 6.4e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain PPR_2 PF13041.1 EIM85628.1 - 6.9e-18 64.3 0.1 4e-12 45.9 0.1 3.9 3 0 0 3 3 3 3 PPR repeat family PPR PF01535.15 EIM85628.1 - 8.6e-15 53.6 3.3 0.0083 16.0 0.0 6.7 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.2 EIM85628.1 - 4.3e-10 38.8 0.4 0.00064 19.1 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 EIM85628.1 - 4.4e-09 35.9 2.2 0.015 15.5 0.0 6.0 6 0 0 6 6 6 2 Pentatricopeptide repeat domain Ribophorin_I PF04597.9 EIM85630.1 - 5.9e-112 374.3 0.0 6.9e-112 374.1 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.14 EIM85631.1 - 3.3e-20 71.9 0.4 6.2e-20 71.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GILT PF03227.11 EIM85632.1 - 5.3e-10 39.1 0.2 5.3e-10 39.1 0.1 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) 7kD_coat PF02495.12 EIM85632.1 - 0.026 13.9 0.2 0.059 12.8 0.1 1.6 1 0 0 1 1 1 0 7kD viral coat protein Cid2 PF09774.4 EIM85633.1 - 3.6e-28 98.5 1.9 5.9e-28 97.8 1.3 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 ATG16 PF08614.6 EIM85633.1 - 0.021 14.6 0.5 0.028 14.2 0.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) NAD_Gly3P_dh_N PF01210.18 EIM85633.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-H2C2_2 PF13465.1 EIM85634.1 - 4.6e-05 23.4 3.5 4.6e-05 23.4 2.4 2.4 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM85634.1 - 0.0072 16.5 5.8 0.0072 16.5 4.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM85634.1 - 0.015 15.5 7.3 0.015 15.5 5.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 EIM85634.1 - 0.049 13.4 0.3 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain DUF1924 PF09086.6 EIM85634.1 - 0.099 12.7 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1924) zf-C2H2_2 PF12756.2 EIM85634.1 - 0.14 12.3 4.0 0.17 12.0 2.8 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNR_inhib PF08591.5 EIM85635.1 - 3.7e-06 27.7 0.6 7.7e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Kelch_4 PF13418.1 EIM85636.1 - 1.5e-15 56.6 16.8 0.0016 18.2 0.2 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EIM85636.1 - 2.3e-15 56.2 21.8 0.0021 18.1 0.0 7.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EIM85636.1 - 1.8e-05 24.1 4.6 0.031 13.8 0.2 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EIM85636.1 - 8.7e-05 22.3 3.5 5.7 7.0 0.0 5.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EIM85636.1 - 0.036 14.2 11.4 0.51 10.6 0.0 5.8 6 0 0 6 6 6 0 Kelch motif DUF423 PF04241.10 EIM85636.1 - 0.56 10.1 7.6 0.095 12.6 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF4199 PF13858.1 EIM85637.1 - 5.5 6.8 4.3 12 5.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) HSP90 PF00183.13 EIM85638.1 - 7.3e-120 400.8 8.8 9.6e-120 400.4 6.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EIM85638.1 - 2.3e-10 40.2 0.0 8e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIM85638.1 - 8.3e-06 25.4 0.0 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FF PF01846.14 EIM85639.1 - 9.6e-40 134.3 17.6 3.4e-10 39.7 0.0 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.21 EIM85639.1 - 1.9e-07 30.8 9.5 5.5e-05 22.9 0.6 2.8 3 0 0 3 3 3 2 WW domain Daxx PF03344.10 EIM85639.1 - 2.5 6.4 45.1 0.23 9.8 2.6 2.3 2 0 0 2 2 2 0 Daxx Family Peroxidase_2 PF01328.12 EIM85640.1 - 1.8e-26 92.5 0.0 2.8e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 EIM85641.1 - 7.6e-39 133.4 14.1 1.2e-38 132.7 9.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_8 PF13621.1 EIM85642.1 - 6.4e-16 58.6 0.0 1.5e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Peptidase_S10 PF00450.17 EIM85643.1 - 1.9e-96 323.7 0.0 2.7e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ATP-synt_E PF05680.7 EIM85644.1 - 0.16 11.9 5.2 0.33 10.9 3.6 1.5 1 0 0 1 1 1 0 ATP synthase E chain PBP_sp32 PF07222.7 EIM85644.1 - 0.57 9.3 5.6 0.96 8.5 3.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNase_H2-Ydr279 PF09468.5 EIM85644.1 - 1.2 8.2 5.2 1.9 7.6 3.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SNF2_N PF00176.18 EIM85645.1 - 2.7e-67 226.6 0.2 5.7e-67 225.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.6 EIM85645.1 - 2.5e-16 59.5 0.0 5.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4 PF00097.20 EIM85645.1 - 5.3e-08 32.3 5.3 1e-07 31.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM85645.1 - 5.8e-08 32.6 6.5 1.1e-07 31.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85645.1 - 4.5e-07 29.4 3.1 8.3e-07 28.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM85645.1 - 7.2e-07 28.9 5.1 1.5e-06 27.9 3.5 1.6 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EIM85645.1 - 1.5e-06 28.0 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EIM85645.1 - 6.1e-06 25.8 3.1 1.1e-05 25.0 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM85645.1 - 5.2e-05 23.0 7.3 0.00011 21.9 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.10 EIM85645.1 - 8.2e-05 22.5 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PARP PF00645.13 EIM85645.1 - 0.0026 17.9 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-rbx1 PF12678.2 EIM85645.1 - 0.019 15.0 2.5 0.057 13.5 1.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger WW PF00397.21 EIM85645.1 - 0.043 13.6 0.1 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 WW domain zf-RING_6 PF14835.1 EIM85645.1 - 0.27 11.0 2.3 0.6 9.9 1.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mgm101p PF06420.7 EIM85646.1 - 1.9e-90 300.7 0.0 2.2e-90 300.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DASH_Spc19 PF08287.6 EIM85647.1 - 2.1e-20 72.8 10.4 1.2e-18 67.1 7.2 2.0 1 1 0 1 1 1 1 Spc19 NuA4 PF09340.5 EIM85647.1 - 0.033 13.8 1.4 0.033 13.8 1.0 2.0 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Prefoldin_2 PF01920.15 EIM85647.1 - 0.053 13.2 12.3 0.47 10.2 2.4 2.3 2 1 0 2 2 2 0 Prefoldin subunit MCM_N PF14551.1 EIM85647.1 - 0.17 12.3 0.8 0.28 11.6 0.4 1.5 1 1 0 1 1 1 0 MCM N-terminal domain DEDD_Tnp_IS110 PF01548.12 EIM85647.1 - 0.23 11.1 2.0 0.93 9.1 0.8 2.2 2 1 0 2 2 2 0 Transposase Prefoldin PF02996.12 EIM85647.1 - 3.3 7.3 8.7 1.6 8.3 1.3 2.7 2 1 0 3 3 3 0 Prefoldin subunit FlxA PF14282.1 EIM85647.1 - 9.7 6.2 8.9 4.8 7.1 0.8 2.3 1 1 1 2 2 2 0 FlxA-like protein MoCF_biosynth PF00994.19 EIM85648.1 - 7.7e-60 200.4 0.5 1.8e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EIM85648.1 - 9.4e-29 99.8 0.1 1.5e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EIM85648.1 - 1.1e-12 47.7 0.2 4.5e-12 45.7 0.0 2.3 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) B12-binding PF02310.14 EIM85648.1 - 0.065 13.0 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain GDPD PF03009.12 EIM85651.1 - 1.4e-32 113.1 0.0 2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family OPT PF03169.10 EIM85652.1 - 1.2e-125 420.3 24.8 1.4e-125 420.1 17.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein APH PF01636.18 EIM85653.1 - 3.4e-10 40.0 0.2 2.7e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIM85653.1 - 9.9e-05 21.6 0.0 0.00013 21.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Acyltransferase PF01553.16 EIM85654.1 - 2.2e-33 114.5 0.0 3.1e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase MCPVI PF02993.9 EIM85654.1 - 2.4 8.2 13.3 3.6 7.6 9.2 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Spermine_synth PF01564.12 EIM85655.1 - 1.7e-09 37.0 0.0 2.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase DUF4018 PF13210.1 EIM85655.1 - 1.2 8.4 5.0 2 7.7 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) adh_short PF00106.20 EIM85656.1 - 9.4e-30 103.7 0.6 2.2e-29 102.4 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM85656.1 - 1.7e-12 47.4 1.0 3.1e-11 43.2 0.7 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM85656.1 - 3.5e-08 33.5 0.0 4.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM85656.1 - 0.00078 19.4 0.0 0.0022 18.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM85656.1 - 0.079 12.3 0.2 0.13 11.6 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACT_7 PF13840.1 EIM85658.1 - 5.9e-20 70.5 0.0 1.1e-13 50.5 0.1 2.3 2 0 0 2 2 2 2 ACT domain PGAP1 PF07819.8 EIM85659.1 - 4.6e-51 173.5 0.0 6.5e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIM85659.1 - 1.3e-08 34.7 0.0 4.5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM85659.1 - 4.2e-06 26.7 0.1 1.1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EIM85659.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EIM85659.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_L29 PF00831.18 EIM85660.1 - 2.2e-19 68.9 2.7 2.2e-19 68.9 1.9 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIM85660.1 - 0.0032 17.7 2.1 0.0043 17.3 1.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S9/S16 DUF2870 PF11069.3 EIM85660.1 - 0.1 12.6 0.3 0.1 12.6 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2870) MRP-L47 PF06984.8 EIM85660.1 - 0.31 10.9 3.2 0.38 10.6 0.7 2.2 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Annexin PF00191.15 EIM85660.1 - 0.47 10.4 2.7 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 Annexin His_biosynth PF00977.16 EIM85661.1 - 2.4e-34 118.5 0.0 3e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Fe-ADH PF00465.14 EIM85662.1 - 9.8e-89 297.5 0.0 1.3e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIM85662.1 - 1.6e-11 44.0 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Asp PF00026.18 EIM85663.1 - 6.4e-35 120.9 2.2 2.2e-34 119.1 1.5 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM85663.1 - 4.8e-06 26.6 3.2 8.9e-05 22.4 1.3 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM85663.1 - 0.0019 18.6 0.1 1.4 9.4 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease PepSY_TM_2 PF13703.1 EIM85663.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 PepSY-associated TM helix TMEM154 PF15102.1 EIM85663.1 - 0.019 14.6 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 EIM85663.1 - 0.049 14.0 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NOA36 PF06524.7 EIM85664.1 - 0.51 9.5 3.5 0.68 9.1 2.5 1.1 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EIM85664.1 - 3.1 6.1 8.1 4.3 5.6 5.6 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EIM85664.1 - 5.7 7.2 11.6 10 6.4 8.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 EIM85666.1 - 8.5e-69 231.5 0.0 1.1e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85666.1 - 3.8e-47 160.5 0.0 5.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM85666.1 - 8.8e-06 24.8 0.0 6.9e-05 21.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIM85666.1 - 0.02 14.6 0.0 3.1 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EIM85667.1 - 2.3e-09 36.9 3.3 2.6e-08 33.5 2.3 2.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM85667.1 - 1.2e-06 28.5 0.1 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM85667.1 - 1.4e-05 24.9 2.4 3.1e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM85667.1 - 3.5e-05 23.3 0.0 7.1e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85667.1 - 0.00022 20.8 1.0 0.0015 18.1 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM85667.1 - 0.00038 20.1 1.0 0.0012 18.5 0.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EIM85667.1 - 0.0025 17.3 2.0 0.0031 17.0 0.2 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIM85667.1 - 0.035 13.9 1.0 0.035 13.9 0.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EIM85667.1 - 0.065 13.0 3.2 0.76 9.6 2.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIM85667.1 - 0.066 12.9 0.8 0.15 11.8 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EIM85667.1 - 1.3 8.6 4.2 3.3 7.3 2.9 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 tRNA-synt_2c PF01411.14 EIM85668.1 - 1.4e-05 23.5 0.0 2.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIM85668.1 - 0.0035 17.2 0.1 0.0075 16.1 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.11 EIM85669.1 - 3e-36 124.8 25.6 3e-36 124.8 17.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Polysacc_deac_1 PF01522.16 EIM85670.1 - 1.2e-21 76.6 0.0 2.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase MSP1_C PF07462.6 EIM85670.1 - 0.62 8.3 6.7 0.91 7.8 4.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Golgin_A5 PF09787.4 EIM85670.1 - 2.1 6.8 7.3 3.1 6.1 5.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Polysacc_deac_1 PF01522.16 EIM85671.1 - 3.2e-21 75.2 0.0 1.6e-19 69.7 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide deacetylase DIOX_N PF14226.1 EIM85672.1 - 2.3e-24 86.1 0.2 4e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM85672.1 - 1.1e-18 67.2 0.0 2.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.16 EIM85673.1 - 4e-20 71.6 0.0 7.5e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase BTB PF00651.26 EIM85674.1 - 0.014 15.3 0.2 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain DUF605 PF04652.11 EIM85674.1 - 7.9 5.7 14.1 1.3 8.3 6.5 1.9 2 0 0 2 2 2 0 Vta1 like NAD_binding_8 PF13450.1 EIM85676.1 - 4.2e-14 52.3 0.0 9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIM85676.1 - 1.1e-13 51.1 0.1 9.7e-13 47.9 0.1 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EIM85676.1 - 1.1e-12 47.5 1.0 1.2e-08 34.2 0.0 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM85676.1 - 1.7e-07 30.4 3.3 3e-06 26.3 1.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM85676.1 - 6.2e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85676.1 - 4.1e-06 25.5 0.5 0.0041 15.6 0.5 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 EIM85676.1 - 5.8e-06 25.5 0.6 3e-05 23.2 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EIM85676.1 - 2.5e-05 23.5 0.2 4.9e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM85676.1 - 0.0004 20.7 3.2 0.0027 18.0 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM85676.1 - 0.00051 19.2 0.9 0.001 18.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EIM85676.1 - 0.00099 18.5 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EIM85676.1 - 0.0011 18.7 0.5 0.0042 16.8 0.1 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM85676.1 - 0.0012 17.9 0.6 0.0012 17.9 0.4 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.17 EIM85676.1 - 0.0019 17.1 1.8 0.0019 17.1 1.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIM85676.1 - 0.0022 17.7 1.1 0.0038 16.8 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EIM85676.1 - 0.0028 16.3 2.0 0.047 12.3 0.8 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIM85676.1 - 0.0033 17.5 0.1 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EIM85676.1 - 0.0061 16.9 0.3 0.26 11.7 0.2 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EIM85676.1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EIM85676.1 - 0.085 12.5 0.7 0.15 11.8 0.2 1.6 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EIM85676.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIM85676.1 - 0.11 12.3 0.4 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EIM85676.1 - 0.14 11.5 0.6 0.26 10.6 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 EIM85676.1 - 0.17 12.2 0.1 0.43 10.8 0.0 1.7 2 0 0 2 2 1 0 XdhC Rossmann domain GMC_oxred_N PF00732.14 EIM85676.1 - 0.28 10.2 0.6 4.2 6.4 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_10 PF13460.1 EIM85676.1 - 0.39 10.6 3.1 0.52 10.2 1.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding SQS_PSY PF00494.14 EIM85677.1 - 7e-57 192.7 0.0 9.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EIM85678.1 - 1.5e-113 379.9 0.0 1.8e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Na_H_Exchanger PF00999.16 EIM85679.1 - 2.7e-51 174.2 49.0 3.6e-51 173.8 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.12 EIM85680.1 - 5.2e-65 217.4 5.9 5.8e-65 217.2 4.1 1.0 1 0 0 1 1 1 1 G10 protein TB2_DP1_HVA22 PF03134.14 EIM85681.1 - 1.4e-11 43.9 1.0 1.4e-11 43.9 0.7 2.0 2 1 0 2 2 2 1 TB2/DP1, HVA22 family AA_permease_2 PF13520.1 EIM85682.1 - 2.2e-52 178.0 55.0 2.7e-52 177.7 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM85682.1 - 1.4e-16 59.9 48.6 2.2e-16 59.2 33.7 1.3 1 0 0 1 1 1 1 Amino acid permease Patatin PF01734.17 EIM85682.1 - 0.03 14.2 0.2 0.055 13.3 0.2 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase PufQ PF05398.6 EIM85682.1 - 0.039 13.9 1.1 3.3 7.8 0.1 2.8 2 0 0 2 2 2 0 PufQ cytochrome subunit Polysacc_deac_1 PF01522.16 EIM85683.1 - 7.5e-18 64.3 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EIM85683.1 - 0.0057 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Spc97_Spc98 PF04130.8 EIM85684.1 - 4.6e-59 200.1 1.5 1e-58 199.0 0.1 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family VWA_2 PF13519.1 EIM85685.1 - 5.7e-08 33.0 0.1 9.4e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIM85685.1 - 5.2e-07 29.5 0.1 1.5e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIM85685.1 - 1.1e-05 25.3 0.1 1.8e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 EIM85685.1 - 0.00033 20.3 0.1 0.00099 18.8 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EIM85686.1 - 9.5e-10 38.8 0.0 1.4e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIM85686.1 - 1.7e-06 28.0 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EIM85686.1 - 3e-06 27.0 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EIM85686.1 - 0.062 12.4 0.0 0.15 11.1 0.0 1.7 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein PCI PF01399.22 EIM85687.1 - 3.9e-14 52.8 0.0 9.4e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain Thioredoxin_4 PF13462.1 EIM85688.1 - 5.9e-07 29.6 0.0 9.5e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EIM85688.1 - 0.0083 15.7 0.0 0.059 12.9 0.0 2.2 1 1 1 3 3 3 1 DSBA-like thioredoxin domain PP1_bind PF15276.1 EIM85689.1 - 0.013 15.5 0.2 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 binding Atg14 PF10186.4 EIM85690.1 - 0.065 12.1 0.1 0.14 11.0 0.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GatB_N PF02934.10 EIM85691.1 - 2.5e-103 344.9 0.0 3.4e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EIM85691.1 - 3.8e-30 104.5 0.0 5.3e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 GatB domain DUF4473 PF14747.1 EIM85691.1 - 0.035 14.3 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Beta_helix PF13229.1 EIM85693.1 - 1.6e-06 27.9 28.4 4.9e-05 23.1 19.7 2.8 1 1 0 1 1 1 1 Right handed beta helix region VSP PF03302.8 EIM85693.1 - 1.3 7.5 9.7 0.47 9.0 0.4 2.6 3 0 0 3 3 3 0 Giardia variant-specific surface protein PAP_central PF04928.12 EIM85694.1 - 9.4e-105 348.9 0.0 1.2e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIM85694.1 - 2.1e-43 147.5 0.0 3e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIM85694.1 - 1.1e-08 35.2 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EIM85694.1 - 0.028 11.9 0.0 0.049 11.1 0.0 1.3 1 0 0 1 1 1 0 Nrap protein RRM_1 PF00076.17 EIM85695.1 - 7.9e-18 63.8 0.0 1.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85695.1 - 2.9e-10 39.9 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85695.1 - 3.5e-07 29.9 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YqfQ PF14181.1 EIM85695.1 - 0.56 10.2 4.8 1.3 9.0 3.3 1.6 1 0 0 1 1 1 0 YqfQ-like protein eIF-3_zeta PF05091.7 EIM85696.1 - 1.9e-180 600.9 0.0 2.2e-180 600.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ApbA_C PF08546.6 EIM85697.1 - 2.5e-26 92.1 0.0 3.6e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIM85697.1 - 1.1e-18 67.1 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EIM85697.1 - 0.008 15.1 0.8 0.026 13.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EIM85697.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 EIM85697.1 - 0.04 13.7 0.5 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 ThiF family SnoaL PF07366.7 EIM85698.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DM4_12 PF07841.8 EIM85698.1 - 0.11 12.9 0.1 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 DM4/DM12 family GATA PF00320.22 EIM85699.1 - 1.4e-07 30.7 3.6 2.8e-07 29.7 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 EIM85699.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TRP PF06011.7 EIM85701.1 - 6.6e-48 163.3 30.2 1.6e-47 162.1 21.0 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EIM85701.1 - 0.0006 19.8 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EIM85701.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 ML domain CNH PF00780.17 EIM85702.1 - 0.0046 16.4 0.0 0.88 8.9 0.0 2.3 2 0 0 2 2 2 2 CNH domain Ribosomal_S14 PF00253.16 EIM85703.1 - 0.013 14.8 1.2 0.033 13.5 0.9 1.6 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Alpha_kinase PF02816.13 EIM85704.1 - 0.00051 19.7 0.1 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family TBX PF12598.3 EIM85704.1 - 0.0071 16.7 2.6 0.009 16.3 1.8 1.2 1 0 0 1 1 1 1 T-box transcription factor Nucleoplasmin PF03066.10 EIM85704.1 - 0.048 13.1 2.9 0.046 13.2 2.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EIM85705.1 - 5.7e-258 858.2 26.3 6.7e-258 857.9 18.2 1.0 1 0 0 1 1 1 1 Nop14-like family Iso_dh PF00180.15 EIM85706.1 - 8.6e-127 422.8 0.0 1e-126 422.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NOB1_Zn_bind PF08772.6 EIM85707.1 - 4.8e-27 93.5 0.8 8.8e-27 92.7 0.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EIM85707.1 - 0.11 12.0 2.6 0.42 10.1 0.1 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EIM85707.1 - 1.2 8.4 5.9 2.9 7.2 4.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain P21-Arc PF04062.9 EIM85708.1 - 2.5e-60 203.2 0.0 3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ion_trans PF00520.26 EIM85709.1 - 0.41 9.8 17.1 24 4.1 11.9 2.5 1 1 0 1 1 1 0 Ion transport protein Sld5 PF05916.6 EIM85710.1 - 1.3e-17 64.0 0.1 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3635 PF12330.3 EIM85711.1 - 7.2e-20 70.8 0.1 1.3e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) PP2C PF00481.16 EIM85713.1 - 5.7e-25 88.1 0.0 2.2e-22 79.7 0.0 2.9 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIM85713.1 - 1.5e-06 27.7 0.0 7.8e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C UCH PF00443.24 EIM85714.1 - 5.2e-50 170.0 0.0 7.4e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM85714.1 - 2.8e-22 79.5 0.0 6e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIM85714.1 - 0.026 13.8 0.8 0.26 10.5 0.5 2.5 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C2H2 PF00096.21 EIM85715.1 - 5.9e-12 45.1 23.7 0.00035 20.7 0.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM85715.1 - 4.4e-08 33.0 24.7 0.00057 20.0 0.1 4.7 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM85715.1 - 8.6e-05 22.6 21.3 0.29 11.5 0.7 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EIM85715.1 - 0.00022 21.3 7.2 0.023 14.8 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM85715.1 - 0.00099 19.1 11.9 0.52 10.5 0.2 3.8 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIM85715.1 - 0.0097 16.0 6.5 0.26 11.4 0.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.1 EIM85715.1 - 0.052 13.3 0.4 0.052 13.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) DUF2225 PF09986.4 EIM85715.1 - 0.12 11.8 0.2 0.86 9.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_3 PF07649.7 EIM85715.1 - 0.24 11.4 4.6 15 5.7 0.0 3.6 3 0 0 3 3 3 0 C1-like domain zf-H2C2_5 PF13909.1 EIM85715.1 - 0.38 11.0 6.6 6.4 7.2 1.3 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-CHY PF05495.7 EIM85715.1 - 1.5 8.9 7.0 1.3 9.2 1.5 2.3 1 1 1 2 2 2 0 CHY zinc finger Pex14_N PF04695.8 EIM85715.1 - 2.3 8.2 10.0 1.3 9.0 2.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprT-like PF10263.4 EIM85715.1 - 3.1 7.4 7.7 76 2.9 5.3 2.3 1 1 0 1 1 1 0 SprT-like family DZR PF12773.2 EIM85715.1 - 3.5 7.5 6.3 1.8e+02 2.0 4.3 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.10 EIM85715.1 - 4.2 7.2 10.9 1.5 8.6 1.8 3.1 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 EIM85715.1 - 5.5 7.0 12.0 5 7.1 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.7 EIM85715.1 - 6.5 6.8 7.1 9.3 6.3 0.7 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain F-box PF00646.28 EIM85716.1 - 1.1e-05 24.9 0.9 8.7e-05 22.0 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM85716.1 - 0.0017 18.0 0.5 0.0036 16.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like MIP PF00230.15 EIM85717.1 - 4.5e-24 85.1 8.2 5.5e-24 84.8 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Spore_YtrH PF14034.1 EIM85717.1 - 0.0059 16.5 2.3 0.011 15.6 1.6 1.4 1 0 0 1 1 1 1 Sporulation protein YtrH Cation_ATPase_C PF00689.16 EIM85717.1 - 9.9 5.6 13.4 0.28 10.6 4.2 2.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Metallophos PF00149.23 EIM85718.1 - 4.7e-40 137.1 0.0 6.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fer4 PF00037.22 EIM85719.1 - 6e-14 50.9 17.4 1.8e-08 33.6 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EIM85719.1 - 5.1e-12 45.9 9.7 8.1e-12 45.3 6.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIM85719.1 - 4.2e-10 40.2 7.0 7.2e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EIM85719.1 - 6e-10 38.8 4.7 0.00011 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIM85719.1 - 1e-09 38.0 22.2 6.4e-08 32.2 8.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIM85719.1 - 4.1e-09 36.5 10.3 1e-08 35.3 7.3 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EIM85719.1 - 1.3e-08 35.0 2.7 0.0012 19.1 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EIM85719.1 - 2.7e-08 33.2 15.2 7.2e-05 22.4 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EIM85719.1 - 5.2e-08 32.7 20.0 3.4e-05 23.7 8.2 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EIM85719.1 - 8.1e-08 31.8 18.0 0.00075 19.2 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EIM85719.1 - 2.5e-06 27.3 12.0 0.00066 19.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EIM85719.1 - 1.8e-05 25.0 9.0 0.015 15.7 0.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EIM85719.1 - 0.00024 21.4 11.9 0.042 14.2 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EIM85719.1 - 0.0023 18.4 11.9 0.19 12.3 0.8 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 EIM85719.1 - 0.023 14.8 4.0 0.077 13.1 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 EIM85719.1 - 0.045 14.3 18.1 0.08 13.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 EIM85719.1 - 0.094 12.6 3.7 0.15 11.9 2.5 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Prefoldin_2 PF01920.15 EIM85720.1 - 1.7e-23 82.4 1.4 1.9e-23 82.2 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EIM85720.1 - 0.017 14.7 1.8 0.023 14.3 1.3 1.2 1 0 0 1 1 1 0 IncA protein DASH_Dad3 PF08656.5 EIM85720.1 - 0.02 14.5 3.0 0.1 12.3 1.4 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 STAT_alpha PF01017.15 EIM85720.1 - 0.03 14.0 1.5 0.063 12.9 1.0 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain TBPIP PF07106.8 EIM85720.1 - 0.041 13.4 3.5 0.073 12.6 0.4 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PhoU_div PF01865.11 EIM85720.1 - 0.053 12.6 0.6 1.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF2408 PF10303.4 EIM85720.1 - 0.06 13.4 0.6 0.095 12.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2316 PF10078.4 EIM85720.1 - 0.065 13.2 1.6 0.3 11.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Laminin_II PF06009.7 EIM85720.1 - 0.066 12.9 1.7 0.28 10.9 0.2 2.0 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EIM85720.1 - 0.067 13.0 4.0 0.14 12.0 2.8 1.3 1 1 0 1 1 1 0 Tropomyosin like Baculo_PEP_C PF04513.7 EIM85720.1 - 0.1 12.4 0.6 0.87 9.4 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 EIM85720.1 - 0.11 11.6 2.0 3.4 6.7 0.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Scm3 PF10384.4 EIM85720.1 - 0.12 11.9 0.2 2.4 7.7 0.0 2.3 2 1 0 2 2 2 0 Centromere protein Scm3 YkyA PF10368.4 EIM85720.1 - 0.12 11.6 1.7 0.82 8.9 0.1 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Spc24 PF08286.6 EIM85720.1 - 0.19 11.4 3.0 0.16 11.6 1.2 1.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Borrelia_lipo_1 PF05714.6 EIM85720.1 - 0.19 10.8 2.1 1.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Prefoldin PF02996.12 EIM85720.1 - 0.25 11.0 3.3 3.8 7.1 2.3 2.1 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EIM85720.1 - 0.34 10.6 4.0 0.8 9.4 0.9 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 EIM85720.1 - 0.49 8.8 3.6 0.87 8.0 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FKBP_N PF01346.13 EIM85720.1 - 0.53 10.3 3.3 0.65 10.0 0.7 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Trigger_C PF05698.9 EIM85720.1 - 0.55 10.0 4.4 1.8 8.3 3.1 1.8 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Mito_carr PF00153.22 EIM85721.1 - 6.3e-57 189.2 3.2 3.7e-18 65.0 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein GRIM-19 PF06212.7 EIM85724.1 - 3.1e-31 107.7 0.1 3.6e-31 107.5 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box_2 PF09011.5 EIM85725.1 - 1.6e-13 50.7 13.8 2.2e-06 27.9 1.0 2.6 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EIM85725.1 - 2.7e-13 49.9 17.4 2.8e-07 30.6 3.4 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box Acetyltransf_1 PF00583.19 EIM85726.1 - 1.6e-06 27.9 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EIM85726.1 - 4.4e-06 27.2 0.1 0.00045 20.7 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM85726.1 - 5.1e-05 23.3 0.0 7.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM85726.1 - 0.032 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM85726.1 - 0.041 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM85726.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 EIM85726.1 - 0.099 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.1 EIM85727.1 - 1.7e-37 127.1 0.2 7.4e-08 32.2 0.0 11.9 9 2 6 15 15 15 6 PPR repeat family PPR PF01535.15 EIM85727.1 - 1.4e-31 106.2 3.8 0.00063 19.5 0.2 14.0 16 1 0 16 16 16 6 PPR repeat PPR_3 PF13812.1 EIM85727.1 - 1e-30 103.3 19.6 0.024 14.8 0.0 16.0 17 0 0 17 17 17 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIM85727.1 - 7.6e-17 60.4 0.2 0.00029 20.2 0.0 8.7 10 0 0 10 10 10 5 PPR repeat TPR_14 PF13428.1 EIM85727.1 - 1.2e-06 28.6 9.2 15 6.5 0.0 10.3 9 5 5 14 14 14 1 Tetratricopeptide repeat FlgN PF05130.7 EIM85727.1 - 0.025 14.8 1.1 0.078 13.2 0.4 2.1 2 0 0 2 2 2 0 FlgN protein DUF3368 PF11848.3 EIM85727.1 - 0.053 13.0 0.1 0.46 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Velvet PF11754.3 EIM85728.1 - 7.7e-48 162.7 0.0 6.9e-31 107.4 0.0 3.1 2 1 0 2 2 2 2 Velvet factor ArfGap PF01412.13 EIM85729.1 - 1.8e-33 114.8 0.0 2.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Oxysterol_BP PF01237.13 EIM85730.1 - 7.7e-119 396.3 0.1 2e-118 394.9 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EIM85730.1 - 4.7e-15 55.2 0.5 3.3e-07 30.3 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM85730.1 - 8.5e-15 54.8 0.0 1.4e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM85730.1 - 6.2e-14 51.0 0.6 6.1e-05 22.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EIM85730.1 - 7.1e-12 44.3 0.2 0.00053 19.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIM85730.1 - 4.2e-11 43.0 0.2 5.2e-07 30.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EIM85730.1 - 6.3e-11 42.3 0.0 1.7e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EIM85730.1 - 9.2e-05 22.4 0.3 9.2e-05 22.4 0.2 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Sigma70_ner PF04546.8 EIM85730.1 - 0.0073 15.9 3.9 0.016 14.7 2.7 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region Coiled-coil_56 PF09813.4 EIM85731.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.10 EIM85732.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Cu-oxidase PF00394.17 EIM85733.1 - 6.6e-46 156.1 0.0 5.4e-42 143.4 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM85733.1 - 1.4e-35 121.8 7.5 2.6e-33 114.4 0.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM85733.1 - 2e-35 121.0 0.4 7e-34 116.0 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase DUF1314 PF07013.6 EIM85733.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) PIF1 PF05970.9 EIM85734.1 - 0.00029 19.8 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase CENP-B_N PF04218.8 EIM85734.1 - 0.023 14.1 0.9 0.55 9.6 0.4 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HNH_2 PF13391.1 EIM85736.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Dioxygenase_C PF00775.16 EIM85737.1 - 4.8e-06 25.9 0.3 1.2e-05 24.6 0.1 1.6 1 1 1 2 2 2 1 Dioxygenase AAA_5 PF07728.9 EIM85738.1 - 1e-117 388.1 0.0 3.9e-20 71.9 0.0 10.3 9 1 1 10 10 10 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIM85738.1 - 9.3e-25 86.7 0.0 2.9e-08 33.4 0.0 7.9 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EIM85738.1 - 6.4e-24 84.6 0.3 0.00014 22.0 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM85738.1 - 1e-20 74.2 0.1 0.004 17.2 0.0 8.4 7 0 0 7 7 7 4 AAA domain AAA_16 PF13191.1 EIM85738.1 - 1.7e-15 57.5 21.8 0.0012 18.8 0.1 9.1 8 0 0 8 8 8 3 AAA ATPase domain Sigma54_activat PF00158.21 EIM85738.1 - 4.3e-15 55.5 0.0 0.0034 16.8 0.0 5.2 5 0 0 5 5 4 3 Sigma-54 interaction domain AAA_17 PF13207.1 EIM85738.1 - 6.4e-15 56.0 0.0 0.022 15.5 0.0 6.8 5 0 0 5 5 5 3 AAA domain AAA_14 PF13173.1 EIM85738.1 - 1.2e-13 51.0 0.0 0.002 18.0 0.0 6.9 6 0 0 6 6 6 2 AAA domain AAA_18 PF13238.1 EIM85738.1 - 2.6e-12 47.1 1.9 0.05 13.9 0.0 6.3 6 0 0 6 6 5 1 AAA domain T2SE PF00437.15 EIM85738.1 - 5.9e-12 45.0 1.0 0.0062 15.4 0.0 5.7 6 0 0 6 6 5 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EIM85738.1 - 4.1e-11 43.0 3.1 0.0012 18.8 0.0 6.1 7 0 0 7 7 5 2 Sigma-54 interaction domain UPF0079 PF02367.12 EIM85738.1 - 4.6e-11 42.4 0.6 0.21 11.2 0.0 5.6 6 0 0 6 6 5 3 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EIM85738.1 - 5e-10 39.8 0.8 0.82 9.9 0.0 6.3 6 0 0 6 6 5 3 ABC transporter AAA_33 PF13671.1 EIM85738.1 - 1.5e-09 37.8 0.0 0.2 11.4 0.0 6.6 6 0 0 6 6 6 1 AAA domain AAA_19 PF13245.1 EIM85738.1 - 1.5e-09 37.4 9.0 0.0034 17.0 0.1 6.2 7 0 0 7 7 6 3 Part of AAA domain AAA_29 PF13555.1 EIM85738.1 - 1.9e-08 33.6 4.0 0.49 9.9 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain MobB PF03205.9 EIM85738.1 - 2.4e-08 33.7 2.5 2.8 7.6 0.0 5.8 6 0 0 6 6 5 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EIM85738.1 - 5e-08 32.3 0.4 8 5.5 0.0 7.9 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIM85738.1 - 1.8e-07 30.4 0.0 1.7 7.7 0.0 5.7 5 0 0 5 5 5 1 Zeta toxin Miro PF08477.8 EIM85738.1 - 2.3e-07 31.3 0.3 21 5.6 0.0 5.9 5 0 0 5 5 5 0 Miro-like protein AAA_28 PF13521.1 EIM85738.1 - 2.6e-07 30.7 6.1 1.2 9.0 0.0 6.1 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 EIM85738.1 - 2.4e-06 27.3 0.1 2.3 7.8 0.0 5.0 4 0 0 4 4 4 1 NACHT domain RNA_helicase PF00910.17 EIM85738.1 - 2.5e-06 27.6 0.7 24 5.1 0.0 6.2 7 0 0 7 7 5 0 RNA helicase DUF815 PF05673.8 EIM85738.1 - 6.5e-06 25.2 0.0 4.1 6.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIM85738.1 - 3.2e-05 24.3 2.1 10 6.3 0.0 5.5 6 0 0 6 6 5 0 AAA domain SRP54 PF00448.17 EIM85738.1 - 0.00011 21.6 0.0 22 4.4 0.0 4.7 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EIM85738.1 - 0.00012 21.8 0.0 20 4.8 0.0 5.2 5 0 0 5 5 5 0 Archaeal ATPase RuvB_N PF05496.7 EIM85738.1 - 0.00016 20.8 0.2 6.4 5.7 0.0 5.1 5 0 0 5 5 5 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EIM85738.1 - 0.00025 20.7 0.5 10 5.7 0.0 5.1 5 0 0 5 5 4 0 NTPase PduV-EutP PF10662.4 EIM85738.1 - 0.00051 19.5 0.1 1.9 7.9 0.0 4.3 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EIM85738.1 - 0.0008 18.8 7.6 2.1 7.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain DUF258 PF03193.11 EIM85738.1 - 0.0038 16.4 0.3 7.1 5.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function, DUF258 ResIII PF04851.10 EIM85738.1 - 0.005 16.6 0.0 5.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.24 EIM85738.1 - 0.0073 15.8 0.2 8.4 5.8 0.0 3.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.14 EIM85738.1 - 0.024 14.1 3.2 31 3.9 0.0 5.3 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain vWA-TerF-like PF10138.4 EIM85738.1 - 0.059 13.1 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus AAA_24 PF13479.1 EIM85738.1 - 0.065 12.8 0.2 80 2.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain TIP49 PF06068.8 EIM85738.1 - 0.093 11.4 0.1 30 3.1 0.0 3.6 4 0 0 4 4 4 0 TIP49 C-terminus MMR_HSR1 PF01926.18 EIM85738.1 - 0.1 12.5 3.5 22 5.0 0.0 4.6 6 0 0 6 6 4 0 50S ribosome-binding GTPase Herpes_HEPA PF03324.9 EIM85738.1 - 0.17 11.9 0.1 32 4.6 0.0 2.7 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein AAA_7 PF12775.2 EIM85738.1 - 0.28 10.2 0.1 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 PhoH PF02562.11 EIM85738.1 - 0.31 10.2 0.3 23 4.1 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein ATP_bind_1 PF03029.12 EIM85738.1 - 0.4 10.1 1.2 41 3.5 0.0 3.7 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 EIM85738.1 - 0.6 9.1 1.1 40 3.2 0.0 3.0 3 0 0 3 3 2 0 KaiC PIF1 PF05970.9 EIM85738.1 - 0.78 8.6 0.1 1.2e+02 1.4 0.0 3.7 4 0 0 4 4 4 0 PIF1-like helicase AAA_6 PF12774.2 EIM85738.1 - 0.87 9.0 0.0 80 2.6 0.0 3.5 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 Aminotran_1_2 PF00155.16 EIM85740.1 - 1.2e-22 80.4 0.0 1.4e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIM85740.1 - 1.6e-10 40.1 0.0 2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RicinB_lectin_2 PF14200.1 EIM85741.1 - 2.2e-13 50.4 0.0 4.7e-07 30.1 0.0 4.2 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ribosomal_L35p PF01632.14 EIM85742.1 - 5.1e-12 45.5 2.0 6.5e-12 45.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Ufd2P_core PF10408.4 EIM85743.1 - 1.1e-187 625.1 0.1 1.3e-187 624.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EIM85743.1 - 3.5e-28 97.3 1.0 1.9e-27 95.0 0.4 2.4 2 0 0 2 2 2 1 U-box domain Eaf7 PF07904.8 EIM85744.1 - 1.1e-17 63.7 0.0 2.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 RasGEF PF00617.14 EIM85745.1 - 6e-17 61.9 1.2 1.3e-16 60.9 0.8 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIM85745.1 - 7.6e-07 29.1 0.2 1.9e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF4372 PF14294.1 EIM85745.1 - 0.058 13.2 1.2 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) RasGEF PF00617.14 EIM85746.1 - 1.4e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIM85746.1 - 5.3e-06 26.4 0.1 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AMPKBI PF04739.10 EIM85748.1 - 1.2e-15 57.1 0.2 5.7e-15 55.0 0.0 2.2 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DEAD PF00270.24 EIM85750.1 - 2.2e-20 72.8 0.0 5.3e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM85750.1 - 2.4e-16 59.3 0.0 8.1e-14 51.2 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM85750.1 - 0.00097 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 EIM85750.1 - 0.044 12.3 0.1 0.1 11.1 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Aldolase_II PF00596.16 EIM85751.1 - 1.8e-35 122.2 0.0 2.1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PAS_3 PF08447.6 EIM85752.1 - 1.5e-07 31.4 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EIM85752.1 - 0.00011 22.1 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EIM85752.1 - 0.00051 19.7 0.0 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EIM85752.1 - 0.0014 18.9 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain BHD_3 PF10405.4 EIM85753.1 - 3.6e-28 97.0 0.0 7e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EIM85753.1 - 1.6e-25 89.2 0.0 4.5e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EIM85753.1 - 1.5e-17 62.8 0.0 3.3e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EIM85753.1 - 4.8e-13 49.1 0.3 4.8e-13 49.1 0.2 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EIM85753.1 - 8.8e-07 29.1 0.1 8.8e-06 25.9 0.1 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily Hydrolase PF00702.21 EIM85754.1 - 6.5e-13 49.5 0.1 1.4e-12 48.5 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM85754.1 - 7.4e-11 42.5 0.0 6.1e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM85754.1 - 2.5e-08 33.5 0.0 5.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EIM85754.1 - 0.0047 17.1 0.0 0.0094 16.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BTB PF00651.26 EIM85755.1 - 1.1e-06 28.5 0.0 5.7e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain WD40 PF00400.27 EIM85756.1 - 3.8e-32 108.9 0.1 3.5e-08 33.0 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EIM85756.1 - 0.00011 20.5 0.1 0.00024 19.3 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIM85756.1 - 0.0059 16.0 0.1 0.023 14.1 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 EIM85756.1 - 0.0081 14.9 0.4 0.066 11.9 0.3 2.4 1 1 0 1 1 1 1 Nup133 N terminal like Fungal_trans PF04082.13 EIM85757.1 - 1.5e-21 76.4 0.3 1.2e-20 73.5 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM85757.1 - 5.9e-08 32.4 11.3 1e-07 31.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIM85757.1 - 0.029 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain NAD_binding_10 PF13460.1 EIM85758.1 - 6.1e-21 75.2 0.0 1e-20 74.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM85758.1 - 1.8e-12 47.0 0.0 2.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EIM85758.1 - 6.6e-11 41.6 0.0 2.8e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIM85758.1 - 7.4e-11 41.9 0.1 9.1e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM85758.1 - 1.5e-10 40.3 0.0 6.6e-10 38.1 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM85758.1 - 1.2e-08 34.1 0.1 3e-05 23.0 0.1 3.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIM85758.1 - 0.015 15.2 0.0 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EIM85758.1 - 0.023 14.3 0.0 2 8.0 0.0 2.1 1 1 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EIM85758.1 - 0.025 13.5 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EIM85758.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EIM85758.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2462 PF09495.5 EIM85759.1 - 1.7e-19 70.2 15.1 1.9e-19 70.1 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) PP2C_C PF07830.8 EIM85759.1 - 0.0056 16.7 0.3 0.0076 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Colicin PF01024.14 EIM85759.1 - 0.047 13.2 6.5 0.054 13.0 4.5 1.0 1 0 0 1 1 1 0 Colicin pore forming domain Ribosomal_L4 PF00573.17 EIM85759.1 - 0.41 10.0 5.1 0.56 9.5 3.5 1.4 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family DUF1098 PF06497.6 EIM85759.1 - 0.71 9.9 6.1 0.77 9.8 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1098) Ribonuclease PF00545.15 EIM85760.1 - 5.3e-14 52.0 0.1 6.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ribonuclease HTH_Tnp_Tc5 PF03221.11 EIM85761.1 - 4.6e-09 35.9 0.3 1e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EIM85761.1 - 7e-05 22.1 0.1 0.00015 21.0 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EIM85761.1 - 0.00021 20.7 0.2 0.00043 19.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIM85761.1 - 0.00039 19.9 0.4 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.2 EIM85761.1 - 0.00049 19.7 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_Tnp_4 PF13613.1 EIM85761.1 - 0.0037 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_3 PF01381.17 EIM85761.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4 PF04545.11 EIM85761.1 - 0.0095 15.2 0.3 0.035 13.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_31 PF13560.1 EIM85761.1 - 0.014 15.5 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.17 EIM85761.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 EIM85761.1 - 0.026 14.1 0.2 0.56 9.8 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.1 EIM85761.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.11 EIM85761.1 - 0.1 12.2 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_Crp_2 PF13545.1 EIM85761.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MFS_1 PF07690.11 EIM85762.1 - 2.7e-12 46.1 47.0 2.7e-12 46.1 32.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EIM85763.1 - 3e-58 197.0 0.0 4.8e-58 196.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85763.1 - 5.2e-31 107.6 0.0 9e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM85763.1 - 0.0015 17.5 0.0 0.0038 16.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF2235 PF09994.4 EIM85764.1 - 6.7e-73 245.4 0.0 8.6e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIM85764.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EIM85764.1 - 0.088 12.5 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DPBB_1 PF03330.13 EIM85765.1 - 2.3e-07 30.7 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel NifU PF01106.12 EIM85765.1 - 0.16 11.7 0.2 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 NifU-like domain SH3_9 PF14604.1 EIM85766.1 - 2.4e-22 78.2 0.9 1.8e-12 46.6 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIM85766.1 - 1.4e-19 69.2 1.6 6.5e-09 35.0 0.0 2.7 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIM85766.1 - 3.4e-19 68.0 0.1 1.8e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EIM85766.1 - 9.2e-17 61.0 0.1 9.2e-17 61.0 0.1 3.4 4 0 0 4 4 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 EIM85766.1 - 3.6e-12 45.8 4.9 6.4e-12 45.0 3.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 EIM85766.1 - 0.00017 21.6 0.9 0.00029 20.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain AA_synth PF06684.6 EIM85766.1 - 0.025 13.9 0.4 7.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Amino acid synthesis FYVE PF01363.16 EIM85766.1 - 0.032 14.1 1.8 0.082 12.8 1.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger Antitoxin-MazE PF04014.13 EIM85766.1 - 0.034 13.8 0.3 7.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE DUF4241 PF14025.1 EIM85766.1 - 0.064 13.0 2.2 3.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) eIF3_subunit PF08597.5 EIM85766.1 - 0.53 9.8 15.9 0.017 14.6 6.6 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF778 PF05608.7 EIM85766.1 - 0.78 9.6 4.4 29 4.5 3.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF778) CAF1 PF04857.15 EIM85767.1 - 2.1e-65 220.6 0.0 3.4e-65 219.9 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease MFS_1 PF07690.11 EIM85768.1 - 1.8e-17 63.1 38.7 1.8e-17 63.1 26.9 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Ribonuclease PF00545.15 EIM85769.1 - 5.5e-13 48.8 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ribonuclease MARVEL PF01284.18 EIM85770.1 - 1.4e-05 24.9 12.5 0.00035 20.4 5.7 2.0 1 1 1 2 2 2 2 Membrane-associating domain CitMHS PF03600.11 EIM85770.1 - 0.08 11.5 3.3 0.11 11.0 2.3 1.2 1 0 0 1 1 1 0 Citrate transporter DUF3382 PF11862.3 EIM85770.1 - 9 6.2 12.3 11 5.9 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3382) FHA PF00498.21 EIM85771.1 - 4.4e-16 58.7 0.0 7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF1325 PF07039.6 EIM85772.1 - 1.3e-30 105.6 0.1 1.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 EIM85772.1 - 0.0085 16.2 0.1 0.075 13.1 0.0 2.3 2 1 0 2 2 2 1 Agenet domain EBP PF05241.7 EIM85774.1 - 1.4e-63 213.4 9.0 1.7e-63 213.1 6.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 EIM85774.1 - 0.17 11.6 6.2 0.12 12.1 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) F-box-like PF12937.2 EIM85775.1 - 0.00034 20.2 0.0 0.0013 18.3 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM85775.1 - 0.52 9.9 3.3 12 5.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) BLOC1_2 PF10046.4 EIM85777.1 - 0.29 11.3 0.2 0.54 10.4 0.2 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box-like PF12937.2 EIM85778.1 - 4e-08 32.8 0.0 1.2e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like FYRC PF05965.9 EIM85780.1 - 2.9e-16 59.0 0.0 4.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 EIM85780.1 - 3.3e-12 45.6 0.1 4.8e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF4658 PF15555.1 EIM85780.1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) p450 PF00067.17 EIM85782.1 - 6.6e-57 193.0 0.0 3.2e-45 154.5 0.0 4.0 2 1 1 3 3 3 3 Cytochrome P450 p450 PF00067.17 EIM85783.1 - 5.3e-57 193.3 0.0 7.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EIM85784.1 - 2.2e-60 203.7 0.0 2.8e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF972 PF06156.8 EIM85785.1 - 0.009 16.3 18.0 0.057 13.7 2.4 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF972) CCDC155 PF14662.1 EIM85785.1 - 0.04 13.5 19.3 2.2 7.8 11.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Na_H_antiporter PF03553.9 EIM85785.1 - 0.059 12.3 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter family Reo_sigmaC PF04582.7 EIM85785.1 - 0.33 10.1 11.2 0.45 9.6 5.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EIM85785.1 - 0.54 10.0 25.9 21 4.8 15.1 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EIM85785.1 - 0.58 10.4 22.5 0.064 13.5 3.7 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF904) IncA PF04156.9 EIM85785.1 - 1 8.9 25.9 4.3 6.8 4.8 3.0 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 EIM85785.1 - 1 7.9 20.1 0.043 12.4 8.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HAUS6_N PF14661.1 EIM85785.1 - 2.3 7.5 11.2 0.9 8.8 1.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_1 PF00170.16 EIM85785.1 - 2.5 8.0 17.3 1.4 8.9 0.2 4.8 4 1 1 5 5 5 0 bZIP transcription factor Phage_GP20 PF06810.6 EIM85785.1 - 6 6.2 20.1 0.015 14.7 3.8 3.0 1 1 2 3 3 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EIM85785.1 - 6.6 6.6 19.7 4.8 7.0 2.1 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding HA2 PF04408.18 EIM85786.1 - 3.8e-21 75.0 0.7 1.3e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM85786.1 - 5.7e-20 71.2 0.1 4.1e-19 68.4 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM85786.1 - 5e-14 51.9 0.0 7.5e-13 48.1 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM85786.1 - 4.4e-06 26.2 0.1 1.3e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIM85786.1 - 5.7e-06 26.5 0.3 3.1e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EIM85786.1 - 0.00024 21.4 4.1 0.069 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EIM85786.1 - 0.01 15.6 0.3 0.36 10.6 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EIM85786.1 - 0.048 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC SEN1_N PF12726.2 EIM85787.1 - 6e-125 418.0 0.0 6e-125 418.0 0.0 1.6 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.1 EIM85787.1 - 4.9e-61 206.3 2.3 1.1e-60 205.1 1.6 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIM85787.1 - 9.9e-59 198.0 0.0 2e-58 197.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM85787.1 - 1.4e-12 47.1 0.4 4.4e-12 45.5 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIM85787.1 - 4.8e-06 26.2 0.1 0.00011 21.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM85787.1 - 0.0031 16.9 0.1 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIM85787.1 - 0.0066 15.9 0.1 0.52 9.6 0.3 3.2 3 2 0 3 3 3 1 AAA-like domain ResIII PF04851.10 EIM85787.1 - 0.0096 15.7 0.4 0.093 12.5 0.3 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EIM85787.1 - 0.0098 15.5 0.1 4.2 6.9 0.0 2.7 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EIM85787.1 - 0.027 14.6 0.0 0.096 12.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM85787.1 - 0.04 14.0 3.4 0.1 12.7 0.6 2.9 1 1 1 2 2 2 0 AAA domain Tagatose_6_P_K PF08013.6 EIM85787.1 - 0.074 11.4 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase AAA_23 PF13476.1 EIM85787.1 - 0.12 12.6 8.7 0.63 10.3 6.0 2.0 1 1 0 1 1 1 0 AAA domain SseC PF04888.7 EIM85787.1 - 0.14 11.4 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family AAA_29 PF13555.1 EIM85787.1 - 0.14 11.7 0.1 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EIM85787.1 - 0.91 8.7 13.7 0.65 9.2 0.0 2.9 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain IncA PF04156.9 EIM85787.1 - 2.5 7.6 9.9 5.5 6.5 6.9 1.5 1 0 0 1 1 1 0 IncA protein Translin PF01997.11 EIM85788.1 - 2.7e-44 151.2 0.0 3.1e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Translin family NADHdeh_related PF10125.4 EIM85788.1 - 0.12 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein Mon1 PF03164.9 EIM85789.1 - 1.2e-101 340.3 0.0 1.4e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 BTB PF00651.26 EIM85790.1 - 4.6e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Period_C PF12114.3 EIM85791.1 - 1.6 8.2 14.5 0.1 12.2 3.4 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region tRNA_bind PF01588.15 EIM85792.1 - 7.5e-28 96.2 0.0 1.3e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EIM85792.1 - 7.2e-06 26.4 0.2 2.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM85792.1 - 0.00034 20.5 0.4 0.00081 19.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM85792.1 - 0.0018 18.1 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.7 EIM85792.1 - 0.016 15.1 0.8 0.023 14.6 0.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.4 EIM85792.1 - 0.035 13.5 9.1 0.052 13.0 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNase_H2-Ydr279 PF09468.5 EIM85792.1 - 1 8.5 5.1 1.4 7.9 3.5 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med3 PF11593.3 EIM85792.1 - 1.2 8.3 7.4 1.7 7.8 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NARP1 PF12569.3 EIM85792.1 - 3.4 6.3 8.8 5.7 5.5 6.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DIOX_N PF14226.1 EIM85793.1 - 3.6e-23 82.2 0.0 6.2e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM85793.1 - 3.7e-10 39.9 0.0 6.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IRF-3 PF10401.4 EIM85793.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 CBFD_NFYB_HMF PF00808.18 EIM85797.1 - 1.3e-06 28.3 0.1 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIM85797.1 - 0.016 15.2 0.1 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Amidohydro_1 PF01979.15 EIM85798.1 - 8.3e-31 107.8 0.0 1e-30 107.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIM85798.1 - 0.0012 18.9 3.2 0.0067 16.4 2.2 2.2 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EIM85798.1 - 0.0088 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 EIM85798.1 - 0.091 11.9 0.5 0.33 10.1 0.1 1.9 2 0 0 2 2 2 0 Amidohydrolase family SKN1 PF03935.10 EIM85799.1 - 3.7e-181 602.6 1.7 5.5e-181 602.1 1.2 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Ribosomal_L6 PF00347.18 EIM85799.1 - 2.1e-21 76.1 0.0 9.2e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 MRP-L47 PF06984.8 EIM85800.1 - 2.6e-20 72.1 4.9 3.1e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) eIF3g PF12353.3 EIM85800.1 - 0.51 10.2 4.7 6.5 6.6 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Complex1_LYR PF05347.10 EIM85801.1 - 3.4e-06 26.7 0.1 4.8e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIM85801.1 - 5.5e-06 26.4 0.1 7.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like F-box-like PF12937.2 EIM85803.1 - 1.2e-10 40.9 10.4 0.00016 21.2 1.4 4.2 2 2 0 2 2 2 2 F-box-like SAC3 PF12209.3 EIM85803.1 - 0.00022 21.3 0.0 0.44 10.7 0.0 2.3 2 0 0 2 2 2 2 Leucine permease transcriptional regulator helical domain DAGK_prokar PF01219.14 EIM85803.1 - 0.032 13.7 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase F-box PF00646.28 EIM85803.1 - 0.034 13.8 6.3 13 5.5 0.0 4.6 5 0 0 5 5 5 0 F-box domain MFS_1 PF07690.11 EIM85805.1 - 3.1e-21 75.4 38.4 1.2e-20 73.5 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Vpu PF00558.14 EIM85805.1 - 0.12 11.9 0.3 0.75 9.3 0.0 2.4 3 0 0 3 3 3 0 Vpu protein GRA6 PF05084.8 EIM85805.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) BatA PF07584.6 EIM85805.1 - 0.18 12.0 2.3 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal vATP-synt_AC39 PF01992.11 EIM85806.1 - 3.3e-103 345.3 0.0 3.7e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit ATP-synt_C PF00137.16 EIM85807.1 - 2e-26 91.6 30.1 3e-16 59.0 6.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF3816 PF12822.2 EIM85807.1 - 2.5 7.9 16.9 0.42 10.5 7.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) KRTAP PF11759.3 EIM85807.1 - 4.1 7.7 8.7 1.3 9.3 1.8 2.2 2 0 0 2 2 2 0 Keratin-associated matrix zf-CCHC_3 PF13917.1 EIM85808.1 - 3e-19 68.4 0.9 3e-19 68.4 0.6 1.7 2 0 0 2 2 2 1 Zinc knuckle Cwf_Cwc_15 PF04889.7 EIM85808.1 - 0.11 12.2 14.6 0.13 11.9 10.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 EIM85808.1 - 0.41 8.8 18.6 0.45 8.7 12.9 1.1 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 EIM85808.1 - 0.75 8.8 25.4 0.87 8.5 17.6 1.1 1 0 0 1 1 1 0 BUD22 FLO_LFY PF01698.11 EIM85808.1 - 0.77 8.5 7.9 0.89 8.3 5.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EIM85808.1 - 0.83 7.6 24.0 0.98 7.3 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 EIM85808.1 - 0.85 9.3 12.5 1.1 9.0 8.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A U79_P34 PF03064.11 EIM85808.1 - 1.8 7.9 24.0 2.5 7.5 16.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Tmemb_cc2 PF10267.4 EIM85808.1 - 3.1 6.2 10.6 3.5 6.1 7.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MIP-T3 PF10243.4 EIM85808.1 - 5.5 5.3 23.3 5.9 5.2 16.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 EIM85808.1 - 7.5 5.8 16.7 9.8 5.4 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) EHN PF06441.7 EIM85810.1 - 6.8e-36 122.5 1.7 1e-34 118.8 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIM85810.1 - 4.7e-09 36.4 0.3 1.2e-08 35.1 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM85810.1 - 4.2e-08 33.0 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 EIM85811.1 - 2.1e-15 56.4 0.0 4.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM85811.1 - 6.3e-10 38.7 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 EIM85812.1 - 5.7e-08 32.3 0.0 1.6e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM85812.1 - 0.17 11.6 0.9 12 5.7 0.0 3.4 3 1 0 3 3 3 0 Leucine rich repeat Nop14 PF04147.7 EIM85812.1 - 2 6.2 28.9 0.011 13.7 2.9 2.2 2 0 0 2 2 2 0 Nop14-like family Homeobox_KN PF05920.6 EIM85813.1 - 5.4e-18 64.3 0.1 1.3e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EIM85813.1 - 4.1e-05 23.1 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain LRR_4 PF12799.2 EIM85814.1 - 1.9e-30 103.9 36.7 1.3e-06 27.8 0.4 9.3 3 2 6 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM85814.1 - 9.5e-24 82.9 36.4 7.3e-07 28.8 1.4 6.8 3 1 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EIM85814.1 - 2.8e-10 38.7 37.1 0.28 11.3 0.1 11.9 11 1 2 13 13 13 4 Leucine Rich Repeat LRR_7 PF13504.1 EIM85814.1 - 5e-09 34.9 33.4 1.2 9.6 0.1 12.1 12 0 0 12 12 12 4 Leucine rich repeat LRR_6 PF13516.1 EIM85814.1 - 9.8e-05 22.0 23.9 27 5.2 1.0 10.5 8 1 2 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.1 EIM85814.1 - 0.00029 20.4 13.0 5.5 6.5 1.0 5.2 3 1 3 6 6 6 4 Leucine-rich repeat Ydc2-catalyt PF09159.5 EIM85815.1 - 0.085 12.3 0.9 0.15 11.4 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 RRM_1 PF00076.17 EIM85816.1 - 2.2e-07 30.4 0.0 4.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85816.1 - 4.3e-06 26.6 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM85816.1 - 4.6e-06 26.4 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIM85816.1 - 2.2e-05 24.1 0.0 4.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EIM85816.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) An_peroxidase PF03098.10 EIM85817.1 - 2.4e-73 247.3 0.0 5.5e-71 239.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EIM85817.1 - 0.018 13.5 0.0 0.036 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 INCENP_N PF12178.3 EIM85817.1 - 0.087 12.3 0.1 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF619 PF04768.8 EIM85818.1 - 1.1e-44 151.8 0.0 1.7e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EIM85818.1 - 6.3e-26 91.0 0.0 1.7e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EIM85818.1 - 2.3e-19 69.9 0.1 4e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 EIM85818.1 - 1.2e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain FAD_binding_4 PF01565.18 EIM85819.1 - 9.1e-14 51.1 0.5 2.2e-13 49.8 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM85819.1 - 2.3e-08 33.8 0.0 7.3e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 EIM85820.1 - 2.6e-32 111.9 70.8 1e-16 60.6 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85820.1 - 1.1e-06 27.5 44.3 0.00016 20.4 13.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EIM85820.1 - 6.2e-05 21.5 40.5 8.8e-05 21.0 14.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein EHN PF06441.7 EIM85821.1 - 1.2e-31 108.9 0.2 1.8e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIM85821.1 - 1.7e-11 44.4 2.1 1.7e-11 44.4 1.4 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM85821.1 - 2.4e-08 33.8 0.0 3.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CG-1 PF03859.11 EIM85821.1 - 0.2 11.2 0.4 0.35 10.4 0.3 1.3 1 0 0 1 1 1 0 CG-1 domain Ribosomal_L23eN PF03939.8 EIM85822.1 - 7.2e-20 70.7 7.6 7.2e-20 70.7 5.3 2.6 2 2 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIM85822.1 - 2.9e-18 65.5 1.1 7.2e-18 64.3 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 ASL_C PF08328.6 EIM85822.1 - 0.0049 16.7 0.1 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal ATP11 PF06644.6 EIM85822.1 - 0.46 9.9 3.9 0.54 9.7 2.7 1.1 1 0 0 1 1 1 0 ATP11 protein DUF1049 PF06305.6 EIM85823.1 - 0.12 11.8 0.2 4.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TPR_11 PF13414.1 EIM85824.1 - 4e-22 77.6 1.3 9e-19 66.8 0.2 2.3 2 0 0 2 2 2 2 TPR repeat RPAP3_C PF13877.1 EIM85824.1 - 4.3e-16 58.6 0.0 7.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.12 EIM85824.1 - 1.3e-13 49.6 4.3 0.0012 18.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM85824.1 - 2.5e-13 49.0 2.0 3.1e-06 26.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM85824.1 - 4.1e-08 33.6 4.7 3.9e-05 24.2 1.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM85824.1 - 2.6e-07 30.6 4.0 0.12 13.0 0.3 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM85824.1 - 1.2e-06 28.7 0.8 0.00021 21.5 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIM85824.1 - 8.6e-06 25.5 0.1 0.0018 18.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM85824.1 - 0.00017 21.3 0.7 0.046 13.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIM85824.1 - 0.006 15.6 0.4 0.52 9.3 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM85824.1 - 0.0067 16.3 2.0 0.019 14.8 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM85824.1 - 0.013 15.2 0.4 5.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM85824.1 - 0.025 14.3 0.3 10 6.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 EIM85825.1 - 1.2e-27 96.6 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EIM85825.1 - 1.1e-21 75.8 15.8 6e-10 38.6 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 EIM85825.1 - 3.3e-16 59.0 0.0 5.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 EIM85825.1 - 0.0067 14.6 0.5 0.037 12.1 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Methyltransf_31 PF13847.1 EIM85827.1 - 1.4e-17 63.6 0.0 3.3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM85827.1 - 3.6e-15 56.2 0.0 1.2e-14 54.5 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM85827.1 - 1.2e-13 51.0 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM85827.1 - 3.9e-13 49.7 0.0 7.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM85827.1 - 3.2e-12 47.0 0.0 6.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM85827.1 - 5.5e-10 38.7 0.0 9.6e-09 34.6 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EIM85827.1 - 9.5e-09 35.0 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EIM85827.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EIM85827.1 - 1.1e-07 30.9 0.0 1.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EIM85827.1 - 9.9e-06 25.0 0.0 3.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EIM85827.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM85827.1 - 0.002 18.1 0.0 0.0063 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIM85827.1 - 0.0045 15.8 0.0 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Fibrillarin PF01269.12 EIM85827.1 - 0.0056 15.6 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin TPMT PF05724.6 EIM85827.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EIM85827.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EIM85827.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 EIM85827.1 - 0.033 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 EIM85827.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EIM85827.1 - 0.045 13.1 0.0 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 EIM85827.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CRAL_TRIO PF00650.15 EIM85828.1 - 3.7e-21 75.2 0.0 5.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM85828.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain BDV_P40 PF06407.6 EIM85828.1 - 0.053 12.3 0.1 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P40 protein Nipped-B_C PF12830.2 EIM85829.1 - 1.4e-50 171.5 3.2 3.6e-49 166.9 2.0 3.1 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EIM85829.1 - 4.7e-15 55.1 0.4 1.9e-14 53.2 0.1 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EIM85829.1 - 0.00063 19.9 6.2 0.016 15.4 0.1 4.8 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.17 EIM85829.1 - 0.0032 17.4 2.6 0.91 9.7 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Transket_pyr PF02779.19 EIM85831.1 - 2.1e-67 226.0 0.0 3.1e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIM85831.1 - 1.4e-57 194.7 0.0 2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Cep57_MT_bd PF06657.8 EIM85832.1 - 3.4e-23 81.3 3.8 2.9e-22 78.4 0.0 3.1 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EIM85832.1 - 1.7e-07 31.0 5.6 1.7e-07 31.0 3.9 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 HxlR PF01638.12 EIM85832.1 - 0.0084 15.7 2.3 0.025 14.1 0.3 2.5 2 1 1 3 3 3 1 HxlR-like helix-turn-helix COG5 PF10392.4 EIM85832.1 - 0.27 11.2 6.4 1.5 8.8 2.3 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Mnd1 PF03962.10 EIM85832.1 - 1.4 8.5 13.7 17 5.0 9.5 2.3 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIM85832.1 - 5 6.6 19.3 27 4.3 13.3 2.2 1 1 0 1 1 1 0 IncA protein DUF663 PF04950.7 EIM85833.1 - 1.5e-89 299.9 0.2 3.3e-89 298.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIM85833.1 - 2.1e-28 97.6 0.0 4.5e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_17 PF13207.1 EIM85833.1 - 8.8e-08 32.9 0.2 8.4e-06 26.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EIM85833.1 - 2.3e-06 27.1 0.0 0.00055 19.4 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EIM85833.1 - 1.8e-05 24.8 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIM85833.1 - 9.7e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EIM85833.1 - 0.00026 20.7 0.0 0.00068 19.3 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIM85833.1 - 0.00057 19.8 0.1 0.0021 17.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EIM85833.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIM85833.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EIM85833.1 - 0.002 18.6 0.0 0.0054 17.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EIM85833.1 - 0.0026 18.0 0.7 0.0064 16.7 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.1 EIM85833.1 - 0.0042 17.3 1.6 0.013 15.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EIM85833.1 - 0.0075 15.9 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EIM85833.1 - 0.0083 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIM85833.1 - 0.0084 15.3 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIM85833.1 - 0.0095 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 EIM85833.1 - 0.0098 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EIM85833.1 - 0.014 15.1 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EIM85833.1 - 0.023 14.3 0.1 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 EIM85833.1 - 0.032 13.6 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM85833.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EIM85833.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 EIM85833.1 - 0.29 9.7 0.0 0.46 9.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF87 PF01935.12 EIM85833.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.8 4 0 0 4 4 3 0 Domain of unknown function DUF87 CoA_transf_3 PF02515.12 EIM85835.1 - 2.3e-63 212.8 0.0 3.6e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III DEAD PF00270.24 EIM85836.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EIM85836.1 - 0.027 13.2 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Nop14 PF04147.7 EIM85837.1 - 0.076 10.9 0.7 0.074 10.9 0.5 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 EIM85837.1 - 0.083 12.7 2.6 0.11 12.3 1.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 EIM85837.1 - 0.083 12.1 1.6 0.084 12.1 1.1 1.1 1 0 0 1 1 1 0 SDA1 COPI_C PF06957.6 EIM85837.1 - 0.24 9.8 2.4 0.24 9.8 1.7 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus hNIFK_binding PF12196.3 EIM85837.1 - 0.5 9.7 0.1 0.5 9.7 0.0 2.4 2 1 0 2 2 2 0 FHA Ki67 binding domain of hNIFK CobT PF06213.7 EIM85837.1 - 6.4 5.8 11.7 7.8 5.5 8.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 EIM85837.1 - 8.6 4.9 12.6 11 4.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Asp_protease PF09668.5 EIM85839.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease HTH_32 PF13565.1 EIM85840.1 - 0.029 15.1 0.4 0.2 12.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain UBN2_2 PF14227.1 EIM85844.1 - 4.7e-12 45.5 0.4 9.5e-12 44.5 0.3 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM85844.1 - 5e-08 32.7 0.5 2.8e-07 30.3 0.3 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIM85844.1 - 0.00085 18.9 0.7 0.0016 18.0 0.2 1.7 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.17 EIM85844.1 - 0.045 13.8 0.1 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF3484 PF11983.3 EIM85846.1 - 0.0071 17.1 0.2 0.01 16.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3484) zf-CCHC PF00098.18 EIM85847.1 - 2.9e-05 23.7 10.6 0.02 14.8 1.3 2.4 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.1 EIM85847.1 - 0.26 10.9 2.7 1 9.1 1.9 2.0 1 1 0 1 1 1 0 Nudix N-terminal ZZ PF00569.12 EIM85847.1 - 0.32 10.5 7.2 1.4 8.4 5.0 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Zn_ribbon_recom PF13408.1 EIM85847.1 - 0.4 10.9 7.1 0.76 10.0 4.9 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1 PF03811.8 EIM85847.1 - 0.41 10.1 5.3 1.3 8.5 3.4 2.1 2 0 0 2 2 2 0 InsA N-terminal domain zf-CCHC_4 PF14392.1 EIM85847.1 - 0.51 10.0 4.8 6.9 6.4 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Dimer_Tnp_hAT PF05699.9 EIM85850.1 - 2.5e-07 30.2 0.0 2.6e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Helicase_C_2 PF13307.1 EIM85851.1 - 3e-51 173.7 0.0 1.8e-50 171.1 0.0 2.3 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EIM85851.1 - 8.2e-43 145.8 0.1 2e-37 128.2 0.0 2.5 1 1 1 2 2 2 2 DEAD_2 DEAD PF00270.24 EIM85851.1 - 0.00016 21.1 0.1 0.13 11.7 0.0 2.9 2 1 1 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIM85851.1 - 0.0011 18.7 0.4 0.95 9.2 0.3 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM85851.1 - 0.0021 18.2 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EIM85851.1 - 0.05 12.8 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EIM85851.1 - 0.06 12.3 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EIM85851.1 - 0.15 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EIM85851.1 - 0.46 10.0 0.0 0.46 10.0 0.0 2.8 2 1 1 3 3 3 0 AAA domain ERG4_ERG24 PF01222.12 EIM85852.1 - 2.2e-138 461.4 2.3 2.5e-138 461.2 1.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIM85852.1 - 3.6e-06 27.0 0.0 3.6e-06 27.0 0.0 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EIM85852.1 - 3.2e-05 23.3 0.2 7.9e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIM85852.1 - 0.00058 20.0 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Na_Ca_ex PF01699.19 EIM85854.1 - 5.3e-25 87.6 31.1 1.4e-13 50.6 5.0 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EIM85854.1 - 4.9e-11 42.8 15.6 4.9e-11 42.8 10.8 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF307) DUF4131 PF13567.1 EIM85854.1 - 2.5 7.4 12.9 12 5.2 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Carn_acyltransf PF00755.15 EIM85855.1 - 9.1e-165 549.0 0.0 1e-164 548.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3328 PF11807.3 EIM85856.1 - 0.09 12.4 0.6 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Mito_carr PF00153.22 EIM85857.1 - 1.4e-74 245.8 0.2 1.5e-25 88.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF427 PF04248.7 EIM85858.1 - 3.9e-30 103.3 0.8 4.3e-30 103.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF3684 PF12449.3 EIM85859.1 - 0 1168.9 0.0 0 1168.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EIM85859.1 - 0.0012 18.5 0.0 0.0076 15.8 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIM85859.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GFA PF04828.9 EIM85860.1 - 7.6e-17 61.0 1.6 1.1e-16 60.5 1.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EIM85860.1 - 0.005 16.5 1.1 0.0058 16.3 0.0 1.7 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 EIM85860.1 - 0.018 14.8 2.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.11 EIM85860.1 - 0.27 10.9 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.1 EIM85860.1 - 1.8 8.3 0.0 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Nudix N-terminal OB_NTP_bind PF07717.11 EIM85862.1 - 9.2e-30 102.8 0.1 1.6e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIM85862.1 - 4.2e-27 94.1 0.0 6.7e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) HpcH_HpaI PF03328.9 EIM85863.1 - 1.4e-42 145.1 0.0 2e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EIM85863.1 - 2.8e-12 46.1 0.0 4.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CwfJ_C_1 PF04677.10 EIM85864.1 - 1.4e-32 111.9 0.0 2e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIM85864.1 - 3.4e-26 91.5 0.2 7.1e-25 87.3 0.1 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 EIM85865.1 - 8.1e-66 221.8 0.0 1.4e-65 221.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85865.1 - 6.3e-36 123.7 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EIM85865.1 - 8.1e-24 83.1 18.8 2.1e-16 59.4 3.0 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EIM85865.1 - 1.7e-20 72.5 28.5 2.6e-11 43.0 7.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EIM85865.1 - 2.6e-10 40.6 0.1 2.6e-10 40.6 0.1 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.25 EIM85865.1 - 3.6e-05 23.5 0.0 9.4e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain Uds1 PF15456.1 EIM85865.1 - 0.018 15.0 13.5 0.089 12.7 1.1 2.7 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.11 EIM85865.1 - 1.8 8.4 17.4 5.7 6.8 2.5 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger IncA PF04156.9 EIM85865.1 - 6.1 6.3 7.1 15 5.0 4.9 1.7 1 0 0 1 1 1 0 IncA protein zf-RING-like PF08746.6 EIM85865.1 - 8.5 6.4 20.9 0.58 10.2 6.4 2.4 2 0 0 2 2 2 0 RING-like domain Endosulfine PF04667.12 EIM85866.1 - 3.5e-20 71.7 0.1 5.5e-20 71.1 0.0 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.11 EIM85868.1 - 2.3e-28 98.9 0.1 3.2e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EIM85868.1 - 6.6e-25 88.1 0.2 2e-14 53.7 0.3 2.3 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.1 EIM85868.1 - 0.18 10.9 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily SET PF00856.23 EIM85869.1 - 2.1e-24 86.6 3.1 2.6e-24 86.3 0.0 2.7 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.11 EIM85869.1 - 1.3e-13 51.1 3.7 1.3e-13 51.1 2.6 2.1 2 0 0 2 2 2 1 Pre-SET motif RasGEF PF00617.14 EIM85870.1 - 1.6e-60 204.0 0.2 4.6e-60 202.5 0.2 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIM85870.1 - 3.5e-18 65.6 1.5 3.5e-18 65.6 1.0 2.3 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 EIM85870.1 - 2.9e-17 61.7 0.3 7.4e-17 60.4 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIM85870.1 - 2.2e-14 52.7 0.4 5.3e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM85870.1 - 9.6e-13 47.4 0.0 1.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EIM85870.1 - 1.4e-05 24.7 0.1 0.053 13.3 0.0 2.7 2 0 0 2 2 2 2 WW domain DUF416 PF04222.7 EIM85870.1 - 0.0028 16.8 0.2 0.0083 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF416) GTP_EFTU PF00009.22 EIM85871.1 - 2.1e-51 174.0 0.0 3.2e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIM85871.1 - 6.6e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIM85871.1 - 7e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIM85871.1 - 3.1e-06 27.1 0.1 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EIM85871.1 - 8.9e-06 25.7 0.3 3.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EIM85871.1 - 0.00089 18.8 0.2 0.014 14.9 0.0 2.9 2 1 0 2 2 2 1 Elongation factor G, domain IV Miro PF08477.8 EIM85871.1 - 0.0037 17.7 0.1 0.0086 16.5 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIM85871.1 - 0.055 12.6 0.1 0.23 10.6 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 EIM85872.1 - 5.8e-44 149.6 0.1 7.8e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EIM85872.1 - 2.6e-07 30.2 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EIM85872.1 - 7.5e-05 22.2 0.1 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM85872.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EIM85872.1 - 0.0045 16.2 0.7 0.3 10.2 0.3 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_10 PF12846.2 EIM85872.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EIM85872.1 - 0.0088 14.8 0.3 0.21 10.3 0.0 2.5 3 0 0 3 3 3 1 ArgK protein Viral_helicase1 PF01443.13 EIM85872.1 - 0.01 15.3 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EIM85872.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIM85872.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIM85872.1 - 0.037 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM85872.1 - 0.044 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EIM85872.1 - 0.11 12.2 0.1 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UAA PF08449.6 EIM85873.1 - 6.2e-67 225.6 8.4 2.1e-66 223.9 5.8 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIM85873.1 - 1.5e-07 31.4 9.3 1.5e-07 31.4 6.4 4.6 3 1 2 5 5 5 1 EamA-like transporter family EmrE PF13536.1 EIM85873.1 - 0.00032 20.8 2.8 0.00032 20.8 2.0 4.1 5 0 0 5 5 5 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EIM85873.1 - 0.00079 18.6 4.7 0.23 10.5 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EIM85873.1 - 0.0049 16.5 12.0 0.013 15.1 5.3 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 EIM85873.1 - 0.24 11.2 4.0 1.5 8.6 0.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Pyr_redox_3 PF13738.1 EIM85874.1 - 4.3e-13 49.8 0.0 3.2e-06 27.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM85874.1 - 5.4e-13 47.9 0.0 6.9e-07 27.8 0.0 2.9 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIM85874.1 - 9.3e-10 38.4 0.0 2.7e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM85874.1 - 9.7e-10 38.6 0.0 1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM85874.1 - 1.1e-05 24.1 0.0 1.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EIM85874.1 - 1.1e-05 25.2 0.4 0.00033 20.4 0.3 2.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EIM85874.1 - 7.6e-05 21.9 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EIM85874.1 - 8.7e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM85874.1 - 0.00019 20.6 0.0 0.00042 19.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIM85874.1 - 0.00024 21.4 0.0 0.0009 19.6 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM85874.1 - 0.00061 18.7 0.0 0.0029 16.5 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM85874.1 - 0.00084 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 EIM85874.1 - 0.0011 18.0 0.0 0.28 10.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EIM85874.1 - 0.0021 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EIM85874.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 EIM85874.1 - 0.009 16.0 0.1 0.045 13.7 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding FAD_oxidored PF12831.2 EIM85874.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EIM85874.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EIM85874.1 - 0.24 11.2 0.0 1.7 8.4 0.0 2.2 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 EIM85875.1 - 9e-62 209.1 0.0 1.2e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIM85875.1 - 3.8e-08 33.6 0.1 0.0016 18.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM85875.1 - 6e-07 28.4 0.2 3.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EIM85875.1 - 9.9e-07 28.0 0.1 4.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EIM85875.1 - 1.8e-06 27.1 0.1 0.014 14.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM85875.1 - 1.2e-05 25.2 0.1 4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM85875.1 - 2e-05 23.2 0.0 0.0013 17.3 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM85875.1 - 8.4e-05 22.7 0.0 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM85875.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM85875.1 - 0.0019 18.1 0.1 0.021 14.7 0.0 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM85875.1 - 0.0036 16.1 0.1 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIM85875.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Cytochrom_C PF00034.16 EIM85875.1 - 0.013 16.2 0.0 0.031 15.1 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c MAF_flag10 PF01973.13 EIM85875.1 - 0.041 13.4 0.1 12 5.3 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function DUF115 Lycopene_cycl PF05834.7 EIM85875.1 - 0.077 11.9 0.0 0.21 10.4 0.0 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_1 PF00667.15 EIM85876.1 - 2.5e-55 187.2 0.0 1.7e-54 184.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIM85876.1 - 1.8e-31 109.0 1.2 2.4e-31 108.6 0.1 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EIM85876.1 - 1e-19 71.1 0.0 3e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EIM85876.1 - 0.026 14.5 0.0 0.072 13.0 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain She9_MDM33 PF05546.6 EIM85877.1 - 3.9e-70 235.6 7.7 5.1e-70 235.2 5.3 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Sbi-IV PF11621.3 EIM85877.1 - 0.21 11.7 1.9 0.83 9.8 0.4 2.6 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI MbeB_N PF04837.7 EIM85877.1 - 0.23 11.6 7.1 0.47 10.5 0.2 3.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region PP2C_C PF07830.8 EIM85877.1 - 1.3 9.1 4.0 4.7 7.3 0.1 3.0 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain FdhE PF04216.7 EIM85877.1 - 3.4 7.2 6.9 1.3 8.6 1.3 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Methyltransf_23 PF13489.1 EIM85878.1 - 0.00051 19.7 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Leader_Trp PF08255.6 EIM85878.1 - 0.12 12.0 0.3 0.12 12.0 0.2 2.8 3 0 0 3 3 3 0 Trp-operon Leader Peptide HIT PF01230.18 EIM85879.1 - 1.6e-20 73.4 0.2 2.4e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIM85879.1 - 1.3e-15 57.6 0.1 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIM85879.1 - 2.4e-07 30.4 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1631 PF07793.6 EIM85879.1 - 0.071 11.2 0.3 0.087 10.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PGM_PMM_I PF02878.11 EIM85880.1 - 3.6e-38 130.1 0.0 8.2e-38 129.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIM85880.1 - 3.9e-22 78.5 0.0 8e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EIM85880.1 - 7.6e-17 61.3 0.3 3.7e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EIM85880.1 - 8.4e-06 25.7 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 EIM85880.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 TFIIA PF03153.8 EIM85881.1 - 0.61 9.9 18.8 0.76 9.6 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 EIM85881.1 - 0.91 7.1 10.3 1 6.9 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAM-associated PF14303.1 EIM85881.1 - 3.9 7.7 12.3 6.7 7.0 8.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MCM_bind PF09739.4 EIM85882.1 - 3.9e-18 65.1 0.0 6.8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EIM85882.1 - 8.6e-16 58.0 0.4 1.6e-15 57.2 0.3 1.4 1 0 0 1 1 1 1 Putative alanine racemase CBFD_NFYB_HMF PF00808.18 EIM85883.1 - 5.2e-15 55.2 3.1 5.2e-15 55.2 2.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIM85883.1 - 4.2e-10 39.5 0.9 5.5e-10 39.2 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EIM85883.1 - 0.099 12.3 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated MMS1_N PF10433.4 EIM85884.1 - 4.5e-47 160.3 0.0 1.1e-46 159.0 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EIM85884.1 - 1e-46 159.5 0.0 3.8e-44 151.0 0.0 3.5 3 0 0 3 3 3 2 CPSF A subunit region Peptidase_C97 PF05903.9 EIM85886.1 - 7.2e-42 142.7 0.0 1.1e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EIM85886.1 - 1.1e-26 93.3 0.1 1.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EIM85886.1 - 2.9e-14 52.6 0.0 6.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIM85886.1 - 0.00018 21.6 0.1 0.0015 18.6 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EIM85886.1 - 0.019 14.5 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Redoxin EST1 PF10374.4 EIM85887.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Telomerase activating protein Est1 Asp PF00026.18 EIM85888.1 - 6.1e-45 153.8 5.5 1.1e-44 152.9 3.8 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM85888.1 - 3.3e-05 24.2 0.7 7.9e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 Aspartyl protease TAXi_N PF14543.1 EIM85888.1 - 0.0083 16.0 1.2 0.24 11.3 0.9 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal AOX PF01786.12 EIM85890.1 - 2.2e-85 285.2 0.0 2.6e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.1 EIM85891.1 - 1.6e-22 79.9 6.0 9.3e-22 77.4 0.8 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4436 PF14494.1 EIM85892.1 - 1.2e-11 44.4 1.5 2.6e-11 43.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Pkinase_Tyr PF07714.12 EIM85893.1 - 0.024 13.7 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EIM85893.1 - 0.041 13.0 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein kinase domain Ribosom_S12_S23 PF00164.20 EIM85894.1 - 2.7e-44 149.4 2.4 3e-44 149.3 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Pro_dh PF01619.13 EIM85894.1 - 0.13 11.2 0.1 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Proline dehydrogenase zf-Nse PF11789.3 EIM85895.1 - 7.5e-15 54.1 0.0 1.3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EIM85895.1 - 0.0036 17.1 0.2 0.0073 16.1 0.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EIM85895.1 - 0.0053 16.4 0.2 0.015 14.9 0.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIM85895.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Reo_sigmaC PF04582.7 EIM85895.1 - 0.087 11.9 0.3 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein zf-MIZ PF02891.15 EIM85895.1 - 0.11 12.0 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Jnk-SapK_ap_N PF09744.4 EIM85895.1 - 1.8 8.5 9.2 0.21 11.5 2.2 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CTP_transf_2 PF01467.21 EIM85895.1 - 3.3 7.7 6.1 15 5.6 4.2 1.9 1 1 0 1 1 1 0 Cytidylyltransferase UPF0014 PF03649.8 EIM85896.1 - 2.4e-38 131.7 15.0 3.1e-38 131.3 10.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EIM85896.1 - 0.0049 16.6 5.8 0.0049 16.6 4.0 3.0 2 2 0 2 2 2 1 FtsX-like permease family BPD_transp_1 PF00528.17 EIM85896.1 - 0.082 12.4 17.8 0.43 10.0 12.3 2.1 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component NAD_binding_6 PF08030.7 EIM85897.1 - 1.1e-21 77.3 0.0 1.7e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIM85897.1 - 1.2e-17 64.2 5.9 1.2e-17 64.2 4.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIM85897.1 - 9.6e-14 51.1 0.0 3.7e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain F-box-like PF12937.2 EIM85898.1 - 3.3e-05 23.5 2.1 0.0003 20.4 1.5 2.4 1 1 0 1 1 1 1 F-box-like ADH_N PF08240.7 EIM85900.1 - 1.8e-25 88.8 1.2 1.8e-25 88.8 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM85900.1 - 1.4e-09 37.5 0.1 2.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EIM85900.1 - 1.9e-05 24.2 0.1 4.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EIM85900.1 - 0.00031 19.3 0.2 0.0028 16.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EIM85900.1 - 0.0066 16.0 0.1 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EIM85900.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_18 PF12847.2 EIM85900.1 - 0.021 15.4 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 EIM85900.1 - 0.056 13.8 0.1 0.15 12.4 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM85900.1 - 0.058 12.4 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EIM85900.1 - 0.059 12.4 0.5 0.085 11.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM85900.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM85900.1 - 0.078 11.8 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIM85900.1 - 0.11 12.6 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase EHN PF06441.7 EIM85901.1 - 2.3e-35 120.8 1.6 7.2e-35 119.2 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIM85901.1 - 3.4e-10 40.2 1.6 6.6e-10 39.2 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM85901.1 - 3.1e-07 30.1 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HA2 PF04408.18 EIM85902.1 - 2.8e-20 72.2 0.1 5.1e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM85902.1 - 1.3e-15 57.1 0.0 4e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM85902.1 - 1.3e-13 50.5 0.0 7.6e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM85902.1 - 3.4e-08 33.1 0.6 9.4e-08 31.7 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIM85902.1 - 7.5e-05 22.8 0.1 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIM85902.1 - 0.0015 18.8 0.2 0.028 14.7 0.1 2.5 1 1 1 2 2 2 1 ABC transporter AAA_29 PF13555.1 EIM85902.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EIM85902.1 - 0.038 12.8 0.1 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EIM85902.1 - 0.04 13.5 0.3 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIM85902.1 - 0.095 12.4 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EIM85902.1 - 0.11 12.2 0.2 23 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Alpha_L_fucos PF01120.12 EIM85903.1 - 3e-36 125.0 0.0 4.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 EIM85903.1 - 1.2e-06 28.3 0.1 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain 4HBT PF03061.17 EIM85904.1 - 8.1e-10 38.6 0.0 0.00056 19.9 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily p450 PF00067.17 EIM85906.1 - 4.6e-45 153.9 0.0 5.1e-26 91.2 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 cobW PF02492.14 EIM85907.1 - 6.4e-28 97.3 0.0 1.2e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EIM85907.1 - 0.00015 20.6 0.2 0.016 13.9 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 EIM85907.1 - 0.011 16.5 0.3 0.024 15.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EIM85907.1 - 0.013 14.9 0.0 2.9 7.2 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EIM85907.1 - 0.037 14.3 0.1 0.054 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIM85907.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.18 EIM85909.1 - 4.8e-52 176.6 0.2 1.2e-51 175.3 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM85909.1 - 1e-15 57.3 0.0 2.8e-14 52.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIM85909.1 - 8.5e-09 34.6 0.0 3.5e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EIM85909.1 - 1e-05 25.0 20.5 0.00012 21.6 7.0 3.1 2 1 1 3 3 3 2 PHD-finger DEAD PF00270.24 EIM85909.1 - 0.00065 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HVSL PF09749.4 EIM85910.1 - 2.3e-40 138.1 0.0 2.5e-39 134.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein Ribonuclease_P PF00825.13 EIM85910.1 - 0.2 11.5 1.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease P p450 PF00067.17 EIM85912.1 - 3.9e-64 216.8 0.0 4.4e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2706 PF10913.3 EIM85913.1 - 0.24 11.0 3.7 5.8 6.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) Rft-1 PF04506.8 EIM85914.1 - 3.5e-76 256.7 0.0 5.7e-76 256.0 0.0 1.4 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EIM85914.1 - 0.00015 21.1 8.7 0.00015 21.1 6.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 EIM85916.1 - 7.9e-18 64.2 0.1 1.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM85916.1 - 4e-09 36.1 0.1 7.7e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM85916.1 - 0.0002 22.2 0.0 0.00035 21.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Yae1_N PF09811.4 EIM85919.1 - 6.6e-14 51.1 2.2 1e-13 50.5 1.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF3782 PF12644.2 EIM85919.1 - 0.014 15.1 0.5 0.54 10.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Dynactin_p62 PF05502.8 EIM85920.1 - 4.1e-85 286.3 13.3 5.3e-53 180.4 4.7 2.1 1 1 0 2 2 2 2 Dynactin p62 family Rft-1 PF04506.8 EIM85923.1 - 3.6e-78 263.3 0.8 6.1e-78 262.5 0.6 1.4 1 1 0 1 1 1 1 Rft protein Asp PF00026.18 EIM85925.1 - 9.8e-24 84.1 4.1 2.5e-21 76.2 2.9 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM85925.1 - 5.3e-05 23.6 3.6 0.024 15.1 1.1 3.5 2 1 0 2 2 2 2 Aspartyl protease Orthoreo_P10 PF07204.6 EIM85925.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 gag-asp_proteas PF13975.1 EIM85925.1 - 0.00092 18.9 0.3 0.12 12.2 0.1 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Herpes_gE PF02480.11 EIM85925.1 - 0.012 13.8 0.1 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TAXi_N PF14543.1 EIM85925.1 - 0.068 13.1 0.9 4.7 7.1 0.6 2.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.18 EIM85926.1 - 1.4e-23 83.6 5.4 3e-21 75.9 3.7 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM85926.1 - 0.0003 21.2 2.2 0.075 13.5 0.3 3.4 3 1 0 3 3 3 2 Aspartyl protease eIF2A PF08662.6 EIM85927.1 - 5.7e-41 140.3 0.5 8.2e-37 126.7 0.1 4.5 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EIM85927.1 - 2.5e-08 33.4 1.0 0.055 13.3 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat RRM_1 PF00076.17 EIM85927.1 - 1.1e-06 28.1 0.0 2.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85927.1 - 3.9e-06 26.7 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85927.1 - 0.00024 20.8 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4254 PF14063.1 EIM85927.1 - 0.00089 18.8 2.9 0.0015 18.1 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) F-box-like PF12937.2 EIM85928.1 - 9.5e-11 41.2 1.5 3.8e-10 39.3 0.4 2.6 2 1 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EIM85928.1 - 0.0046 16.8 0.6 1.5 9.1 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich repeat F-box PF00646.28 EIM85928.1 - 0.007 15.9 3.6 1.1 9.0 0.0 3.2 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.2 EIM85928.1 - 0.036 13.6 6.2 15 5.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_S9 PF00326.16 EIM85929.1 - 1.9e-46 157.9 0.1 3.7e-46 157.0 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM85929.1 - 1.2e-09 38.1 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM85929.1 - 4.4e-08 33.2 0.3 1.2e-07 31.8 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIM85929.1 - 1.6e-05 23.5 0.0 0.0019 16.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Lipid_DES PF08557.5 EIM85929.1 - 0.19 11.0 2.5 11 5.3 0.2 2.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) NDK PF00334.14 EIM85930.1 - 1.2e-13 51.0 0.0 3.4e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase Aldo_ket_red PF00248.16 EIM85931.1 - 2.6e-59 200.3 0.0 3e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM85932.1 - 1.6e-58 197.7 0.0 1.8e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L34 PF00468.12 EIM85933.1 - 3.4e-19 68.2 9.2 3.4e-19 68.2 6.4 1.4 1 1 1 2 2 2 1 Ribosomal protein L34 zf-RING_2 PF13639.1 EIM85934.1 - 7.1e-14 51.3 1.7 1.4e-13 50.3 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EIM85934.1 - 9e-13 47.7 0.0 1.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.1 EIM85934.1 - 4.6e-07 29.4 0.5 9.2e-07 28.4 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIM85934.1 - 1.1e-06 28.6 1.3 2.4e-06 27.5 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM85934.1 - 2.8e-06 27.2 2.3 5.7e-06 26.2 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM85934.1 - 1.4e-05 24.6 0.9 3.2e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM85934.1 - 0.00011 21.7 1.8 0.00013 21.5 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM85934.1 - 0.059 13.2 0.7 0.19 11.5 0.5 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CCCH PF00642.19 EIM85935.1 - 3.4e-14 52.1 23.4 4.1e-08 32.7 3.2 3.7 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIM85935.1 - 0.28 11.2 16.8 3.7 7.6 4.2 3.8 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type MFS_1 PF07690.11 EIM85937.1 - 2.1e-23 82.6 55.2 4.6e-15 55.1 10.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM85937.1 - 8.7e-22 77.3 19.9 4.4e-20 71.6 1.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Phosphoprotein PF00922.12 EIM85937.1 - 0.73 8.9 2.2 1.3 8.1 1.5 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein HPP PF04982.8 EIM85937.1 - 5.6 6.8 14.6 1.4 8.7 2.6 3.7 3 2 1 4 4 4 0 HPP family Glyco_hydro_16 PF00722.16 EIM85938.1 - 0.00044 19.5 0.0 0.00078 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 adh_short PF00106.20 EIM85939.1 - 4.2e-15 56.0 0.0 3.8e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EIM85939.1 - 4e-06 26.4 0.0 5.3e-05 22.7 0.0 2.0 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM85939.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 1 0 1 1 1 1 KR domain SET PF00856.23 EIM85940.1 - 6e-09 36.4 0.1 1.5e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 EIM85940.1 - 3.6e-08 33.1 12.2 3.6e-08 33.1 8.5 1.7 2 0 0 2 2 2 1 MYND finger DER1 PF04511.10 EIM85941.1 - 6.5e-46 156.3 5.2 7.6e-46 156.1 3.6 1.0 1 0 0 1 1 1 1 Der1-like family Jiraiya PF15038.1 EIM85941.1 - 0.03 13.7 0.8 0.03 13.7 0.5 2.0 2 1 0 2 2 2 0 Jiraiya YTH PF04146.10 EIM85942.1 - 2e-50 170.0 0.0 4.2e-50 168.9 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EIM85942.1 - 1.1e-06 28.2 0.0 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM85942.1 - 0.0099 15.7 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM85942.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_71 PF03659.9 EIM85944.1 - 1.4e-87 293.6 12.2 2.9e-87 292.6 8.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.14 EIM85944.1 - 2.5e-69 229.2 97.3 3.2e-18 65.4 9.7 5.5 5 0 0 5 5 5 4 WSC domain CBM_20 PF00686.14 EIM85944.1 - 1.5e-29 101.4 0.4 1.5e-29 101.4 0.3 3.8 5 0 0 5 5 5 1 Starch binding domain Glyco_hydro_15 PF00723.16 EIM85945.1 - 1.8e-97 326.7 2.4 2.1e-97 326.5 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EIM85945.1 - 4.7e-29 99.8 0.6 1.3e-28 98.4 0.4 1.8 1 0 0 1 1 1 1 Starch binding domain TPR_11 PF13414.1 EIM85946.1 - 6.4e-13 48.1 0.0 7e-09 35.2 0.0 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIM85946.1 - 6.3e-07 28.7 0.0 0.63 9.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM85946.1 - 2.8e-06 26.8 0.0 0.011 15.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 EIM85946.1 - 3e-06 26.8 2.7 3e-06 26.8 1.9 2.0 2 0 0 2 2 2 1 F-box-like TPR_12 PF13424.1 EIM85946.1 - 0.0027 17.6 0.0 0.018 14.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM85946.1 - 0.029 14.2 0.0 7.2 6.5 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM85946.1 - 0.064 13.9 0.2 0.32 11.7 0.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Colicin_C PF12106.3 EIM85946.1 - 0.1 12.2 0.7 21 4.7 0.0 3.2 3 0 0 3 3 3 0 Colicin C terminal ribonuclease domain LRR_7 PF13504.1 EIM85946.1 - 1.9 9.0 7.0 39 5.0 0.1 5.6 6 1 0 6 6 6 0 Leucine rich repeat AAA PF00004.24 EIM85948.1 - 5.3e-41 139.8 0.0 1.1e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM85948.1 - 2.7e-05 24.2 0.1 0.002 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EIM85948.1 - 0.00032 20.4 0.2 0.0031 17.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM85948.1 - 0.00038 20.6 0.4 0.015 15.4 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIM85948.1 - 0.00047 20.1 0.0 0.0076 16.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIM85948.1 - 0.00059 18.9 0.0 0.0012 17.8 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EIM85948.1 - 0.0015 17.7 0.1 0.026 13.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EIM85948.1 - 0.0024 18.6 0.1 0.0061 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM85948.1 - 0.005 16.7 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIM85948.1 - 0.007 15.5 0.1 0.032 13.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIM85948.1 - 0.0075 15.9 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EIM85948.1 - 0.0076 15.6 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EIM85948.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIM85948.1 - 0.032 13.6 1.0 0.45 9.8 0.1 2.4 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIM85948.1 - 0.052 12.4 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EIM85948.1 - 0.072 12.6 0.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NuA4 PF09340.5 EIM85949.1 - 2.7e-23 81.4 1.3 2.7e-23 81.4 0.9 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HR1 PF02185.11 EIM85949.1 - 0.0035 17.0 0.6 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Hr1 repeat Wbp11 PF09429.5 EIM85949.1 - 1.3 9.0 8.9 1.5 8.8 1.2 2.5 2 1 0 2 2 2 0 WW domain binding protein 11 Mod_r PF07200.8 EIM85951.1 - 1.1e-24 87.0 10.7 4.6e-23 81.7 7.4 2.0 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.1 EIM85951.1 - 0.031 14.2 8.9 0.043 13.7 5.7 1.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4515 PF14988.1 EIM85951.1 - 0.046 13.3 5.9 0.074 12.7 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Syntaxin-6_N PF09177.6 EIM85951.1 - 0.046 14.1 2.6 0.092 13.1 0.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 EIM85951.1 - 0.066 12.2 3.7 0.082 11.9 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EIM85951.1 - 0.14 12.1 1.8 1.7 8.6 1.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 EIM85951.1 - 0.18 10.2 1.8 0.19 10.1 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 EIM85951.1 - 0.26 11.6 6.8 4.9 7.5 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 EIM85951.1 - 0.46 10.0 6.1 0.63 9.6 4.2 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_M3_N PF08439.5 EIM85951.1 - 0.82 9.7 5.1 7.9 6.5 1.3 2.5 2 0 0 2 2 2 0 Oligopeptidase F DUF972 PF06156.8 EIM85951.1 - 1.4 9.3 3.7 1.5 9.2 1.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EIM85951.1 - 4.5 7.2 7.0 3.9 7.5 1.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 EIM85951.1 - 5.8 6.9 9.5 1.7 8.6 4.0 2.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Glyco_hydro_61 PF03443.9 EIM85952.1 - 2.6e-67 226.8 0.1 4.3e-67 226.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NCA2 PF08637.5 EIM85953.1 - 5.3e-73 245.4 0.0 8.4e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF3619 PF12279.3 EIM85954.1 - 0.11 12.5 0.3 0.11 12.5 0.2 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) Epimerase PF01370.16 EIM85955.1 - 8.8e-17 61.3 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM85955.1 - 4.6e-14 51.7 0.1 7.3e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM85955.1 - 5.2e-10 39.6 0.0 1.3e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM85955.1 - 4e-09 35.7 0.4 1.5e-08 33.9 0.3 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM85955.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EIM85955.1 - 0.091 12.6 0.0 0.41 10.5 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Glyco_transf_18 PF15024.1 EIM85956.1 - 5.5e-07 28.3 0.0 0.0014 17.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 18 RasGEF PF00617.14 EIM85957.1 - 5.4e-50 169.7 0.0 9.8e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIM85957.1 - 2.6e-20 72.4 0.0 8.6e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EIM85957.1 - 1.1e-13 50.5 0.0 2.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM85957.1 - 1e-12 47.3 0.0 2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM85957.1 - 2.1e-11 43.0 0.0 3.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain F-box PF00646.28 EIM85958.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM85958.1 - 0.00023 20.7 0.7 0.00044 19.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like EF_assoc_2 PF08356.7 EIM85959.1 - 8.7e-34 115.1 0.0 1.6e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EIM85959.1 - 6.3e-31 107.3 0.2 1.2e-19 70.8 0.0 3.3 3 0 0 3 3 3 3 Miro-like protein EF_assoc_1 PF08355.7 EIM85959.1 - 3.6e-29 99.8 0.3 6.7e-29 99.0 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EIM85959.1 - 3.6e-24 84.9 0.0 2.2e-19 69.4 0.0 3.2 3 0 0 3 3 3 1 Ras family EF-hand_1 PF00036.27 EIM85959.1 - 4.8e-10 38.0 1.2 0.00041 19.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIM85959.1 - 3.1e-09 35.9 0.5 0.0021 17.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EIM85959.1 - 1.7e-08 33.4 3.3 0.0006 19.0 0.1 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.16 EIM85959.1 - 4e-08 32.7 0.0 0.0013 17.9 0.0 3.3 3 1 0 3 3 3 2 ADP-ribosylation factor family EF-hand_7 PF13499.1 EIM85959.1 - 5.4e-08 32.8 0.1 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 EIM85959.1 - 2.3e-06 27.7 0.0 0.091 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EIM85959.1 - 2.5e-06 27.4 0.6 0.044 13.6 0.0 3.1 3 0 0 3 3 3 2 Dynamin family AAA_16 PF13191.1 EIM85959.1 - 3.5e-06 27.1 0.5 0.085 12.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EIM85959.1 - 1.1e-05 25.3 0.1 0.0083 16.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EIM85959.1 - 6.4e-05 22.4 0.1 0.055 13.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_10 PF14788.1 EIM85959.1 - 8.2e-05 22.1 2.0 0.0078 15.8 0.1 2.4 2 0 0 2 2 2 1 EF hand ABC_tran PF00005.22 EIM85959.1 - 8.4e-05 22.8 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA PF00004.24 EIM85959.1 - 0.0001 22.4 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIM85959.1 - 0.00011 22.5 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIM85959.1 - 0.00016 21.8 0.1 0.91 9.7 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.1 EIM85959.1 - 0.0002 21.0 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIM85959.1 - 0.0003 20.4 0.2 0.66 9.6 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EIM85959.1 - 0.00048 20.0 0.0 0.72 9.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 EIM85959.1 - 0.00075 18.5 0.0 0.06 12.3 0.0 2.2 2 0 0 2 2 2 1 Septin MobB PF03205.9 EIM85959.1 - 0.0008 19.1 0.1 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EIM85959.1 - 0.00086 19.3 0.1 2.3 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIM85959.1 - 0.00097 18.3 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EIM85959.1 - 0.0015 17.7 0.0 2.4 7.3 0.0 2.9 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit SPARC_Ca_bdg PF10591.4 EIM85959.1 - 0.0018 18.3 0.9 0.086 12.8 0.0 2.7 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region ATP_bind_1 PF03029.12 EIM85959.1 - 0.0028 17.2 1.6 4.2 6.8 0.1 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EIM85959.1 - 0.0033 16.1 0.0 2 7.0 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit Viral_helicase1 PF01443.13 EIM85959.1 - 0.0041 16.6 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase EF-hand_8 PF13833.1 EIM85959.1 - 0.0047 16.5 1.7 2 8.1 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair AAA_17 PF13207.1 EIM85959.1 - 0.0048 17.6 0.3 3 8.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EIM85959.1 - 0.0049 15.8 0.0 0.45 9.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EIM85959.1 - 0.0052 16.2 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EIM85959.1 - 0.01 15.7 0.0 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EIM85959.1 - 0.01 15.5 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 EIM85959.1 - 0.011 15.1 0.1 2.1 7.7 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EIM85959.1 - 0.014 14.7 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 EIM85959.1 - 0.031 13.7 0.0 3.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E Arch_ATPase PF01637.13 EIM85959.1 - 0.048 13.3 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EIM85959.1 - 0.048 13.9 0.3 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIM85959.1 - 0.048 13.1 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EIM85959.1 - 0.063 12.1 0.0 9 5.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 EIM85959.1 - 0.11 11.5 0.2 0.45 9.6 0.0 2.1 3 0 0 3 3 3 0 AIG1 family MCM PF00493.18 EIM85959.1 - 0.11 11.2 0.1 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family cobW PF02492.14 EIM85959.1 - 0.11 11.8 0.1 5 6.5 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EIM85959.1 - 0.12 11.5 0.0 5.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin VWA_2 PF13519.1 EIM85960.1 - 1.5e-09 38.1 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIM85960.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 EIM85960.1 - 0.00081 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Zn_clus PF00172.13 EIM85961.1 - 0.042 13.7 4.0 0.1 12.5 2.8 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Vpu PF00558.14 EIM85962.1 - 1.6 8.3 3.7 8.9 5.9 0.2 2.6 2 0 0 2 2 2 0 Vpu protein Adaptin_binding PF10199.4 EIM85963.1 - 2e-08 34.6 0.0 1.3e-06 28.7 0.0 2.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 CDC37_N PF03234.9 EIM85964.1 - 4e-46 157.5 2.1 4e-46 157.5 1.4 1.8 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EIM85964.1 - 1.3e-32 112.6 0.0 4e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EIM85964.1 - 3.6e-17 62.0 3.4 3.6e-17 62.0 2.4 1.9 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF3824 PF12868.2 EIM85964.1 - 0.04 14.8 0.4 0.04 14.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SRF-TF PF00319.13 EIM85966.1 - 9.2e-23 79.2 0.2 1.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Methyltransf_11 PF08241.7 EIM85967.1 - 7.5e-12 45.5 0.0 2.6e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM85967.1 - 1.2e-10 41.3 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM85967.1 - 3.7e-10 40.3 0.0 8.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM85967.1 - 8.9e-10 38.8 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM85967.1 - 1e-08 35.5 0.0 2.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM85967.1 - 4.7e-08 32.4 0.0 7.5e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIM85967.1 - 1.2e-07 31.4 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM85967.1 - 1.4e-05 25.0 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIM85967.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.11 EIM85967.1 - 0.0074 14.6 0.0 0.011 14.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EIM85967.1 - 0.026 13.5 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EIM85967.1 - 0.09 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Epimerase PF01370.16 EIM85968.1 - 2e-33 115.8 0.1 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exostosin PF03016.10 EIM85968.1 - 1.4e-31 109.7 0.1 2.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.14 EIM85968.1 - 1.5e-21 76.3 0.0 2.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIM85968.1 - 1.7e-13 50.1 0.0 2.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM85968.1 - 2.5e-11 43.0 0.0 1.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EIM85968.1 - 4.8e-07 28.9 0.5 0.00013 20.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EIM85968.1 - 0.00048 20.1 0.1 0.00086 19.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIM85968.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase MBOAT_2 PF13813.1 EIM85969.1 - 4e-15 55.6 1.1 4e-15 55.6 0.8 2.1 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 EIM85969.1 - 0.16 11.0 6.9 0.67 9.0 4.8 2.1 1 1 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family ADH_zinc_N PF00107.21 EIM85970.1 - 1.8e-15 56.6 0.1 3.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM85970.1 - 2.7e-08 33.5 0.0 5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM85970.1 - 0.00023 22.0 0.1 0.00035 21.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiG_N PF11760.3 EIM85970.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Cyclin_N PF00134.18 EIM85971.1 - 2.8e-11 43.0 0.0 1.7e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIM85971.1 - 0.079 12.8 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 Cyclin, C-terminal domain adh_short PF00106.20 EIM85972.1 - 1.9e-13 50.6 0.2 4.6e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM85972.1 - 2.8e-05 23.8 0.1 4.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM85972.1 - 0.0004 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM85972.1 - 0.0089 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIM85972.1 - 0.084 12.6 0.1 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM85973.1 - 1.4e-16 60.6 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM85973.1 - 1.4e-14 53.4 0.0 2.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM85973.1 - 7.3e-12 45.6 2.4 1.7e-10 41.1 0.7 2.5 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM85973.1 - 2.3e-09 36.5 0.1 7.2e-09 34.9 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM85973.1 - 8.3e-06 25.2 0.1 1.5e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM85973.1 - 0.02 14.8 0.2 0.2 11.5 0.1 2.3 1 1 0 1 1 1 0 short chain dehydrogenase Mito_carr PF00153.22 EIM85975.1 - 6.3e-42 141.2 4.2 2.4e-14 52.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Heme_oxygenase PF01126.15 EIM85976.1 - 8.2e-31 107.1 0.0 1.2e-19 70.7 0.0 3.0 2 1 0 2 2 2 2 Heme oxygenase AMP-binding PF00501.23 EIM85977.1 - 7.3e-89 298.0 0.0 1.2e-88 297.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM85977.1 - 0.036 14.9 0.0 0.12 13.2 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Sod_Cu PF00080.15 EIM85978.1 - 7.6e-49 165.5 3.2 9.6e-49 165.1 2.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EIM85978.1 - 0.011 16.3 0.8 1 9.9 0.1 2.1 1 1 1 2 2 2 0 CHRD domain AARP2CN PF08142.7 EIM85978.1 - 0.034 13.6 0.3 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 AARP2CN (NUC121) domain DUF1842 PF08896.5 EIM85978.1 - 0.088 12.5 0.2 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1842) Lipase_GDSL PF00657.17 EIM85979.1 - 0.00053 19.8 3.0 0.0024 17.7 2.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TrbI_Ftype PF09677.5 EIM85979.1 - 0.063 13.1 0.7 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Motile_Sperm PF00635.21 EIM85980.1 - 9.4e-27 92.8 0.2 1.7e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EIM85980.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Pkinase PF00069.20 EIM85981.1 - 2.6e-70 236.5 0.0 3.3e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM85981.1 - 4.1e-30 104.7 0.0 5.8e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIM85981.1 - 2.5e-10 40.6 1.4 7.2e-10 39.2 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIM85981.1 - 7.4e-06 25.1 0.0 1.9e-05 23.7 0.0 1.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIM85981.1 - 0.018 14.7 0.4 0.045 13.4 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM85981.1 - 0.031 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIM85981.1 - 0.11 11.8 0.2 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GST_N_3 PF13417.1 EIM85982.1 - 1.6e-10 41.0 0.1 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM85982.1 - 1.6e-08 34.3 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM85982.1 - 3.1e-05 23.7 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM85982.1 - 0.00027 21.3 0.1 0.00051 20.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM85982.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 EIM85985.1 - 3.2e-41 141.2 32.9 3.2e-41 141.2 22.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PH PF00169.24 EIM85986.1 - 0.014 15.5 0.2 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 PH domain RA PF00788.18 EIM85986.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain WD40 PF00400.27 EIM85987.1 - 0.0052 16.6 0.2 6.1 6.8 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Homeobox PF00046.24 EIM85988.1 - 1.2e-05 24.7 0.4 2.2e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Apc15p PF05841.6 EIM85988.1 - 7.4 7.3 8.3 3.5 8.3 1.9 2.3 2 0 0 2 2 2 0 Apc15p protein MIP PF00230.15 EIM85990.1 - 2.4e-06 27.1 0.1 3.1e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 EIM85991.1 - 1.2e-47 162.2 9.9 1.4e-47 162.0 6.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1418 PF07214.7 EIM85991.1 - 0.031 13.8 1.0 0.056 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) NTR2 PF15458.1 EIM85992.1 - 1.2e-58 198.3 11.2 2.1e-58 197.5 5.6 2.3 2 0 0 2 2 2 1 Nineteen complex-related protein 2 GCFC PF07842.7 EIM85992.1 - 5.5e-06 25.9 0.0 7e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Hanta_nucleocap PF00846.13 EIM85992.1 - 0.031 12.9 0.0 0.062 11.9 0.0 1.4 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Rad60-SLD PF11976.3 EIM85993.1 - 4.9e-09 35.7 0.1 2.2e-07 30.4 0.1 3.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like mRNA_triPase PF02940.10 EIM85994.1 - 2.4e-49 167.9 0.0 2.9e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Zip PF02535.17 EIM85995.1 - 1.6e-35 122.6 2.6 1.9e-35 122.4 1.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PhyH PF05721.8 EIM85996.1 - 0.00049 20.1 0.1 0.19 11.7 0.0 2.7 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) Mit_KHE1 PF10173.4 EIM85997.1 - 4.5e-48 163.5 0.4 5.9e-48 163.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related F-box-like PF12937.2 EIM85999.1 - 1.4e-05 24.7 0.7 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like ATPase-cat_bd PF12156.3 EIM85999.1 - 0.17 12.4 0.3 0.33 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase TMEM223 PF14640.1 EIM86002.1 - 0.001 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 Glyco_hydro_43 PF04616.9 EIM86003.1 - 6.4e-27 94.3 0.6 7.7e-27 94.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CH PF00307.26 EIM86004.1 - 2.1e-39 133.8 0.0 8.4e-25 86.9 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EIM86004.1 - 6.8e-18 64.4 0.0 6.9e-17 61.1 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EIM86004.1 - 1.5e-12 47.0 0.2 1.5e-10 40.5 0.1 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.1 EIM86004.1 - 0.00095 18.8 0.0 0.0049 16.6 0.0 2.3 2 0 0 2 2 1 1 EF-hand domain Seryl_tRNA_N PF02403.17 EIM86004.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.5 EIM86004.1 - 0.0031 16.7 0.3 0.26 10.4 0.0 2.5 2 0 0 2 2 2 1 Vps5 C terminal like HAUS-augmin3 PF14932.1 EIM86004.1 - 0.0049 16.0 1.1 0.013 14.6 0.7 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.4 EIM86004.1 - 0.017 14.9 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIF4G PF02854.14 EIM86004.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 MIF4G domain NPV_P10 PF05531.7 EIM86004.1 - 0.019 15.2 0.6 4.1 7.7 0.2 3.6 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.6 EIM86004.1 - 0.021 13.9 1.0 0.041 13.0 0.7 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EIM86004.1 - 0.023 14.5 0.2 0.023 14.5 0.1 2.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_7 PF13499.1 EIM86004.1 - 0.025 14.7 0.3 0.13 12.4 0.2 2.2 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EIM86004.1 - 0.025 13.8 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 0 EF hand HrpB7 PF09486.5 EIM86004.1 - 0.046 13.6 4.8 0.71 9.7 3.3 2.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.16 EIM86004.1 - 0.11 12.7 3.2 12 6.2 0.1 3.2 1 1 2 3 3 3 0 Spectrin repeat Fib_alpha PF08702.5 EIM86004.1 - 0.27 11.3 2.7 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 EIM86004.1 - 0.44 10.7 4.4 1.2 9.3 0.4 3.0 2 2 1 3 3 3 0 Syntaxin Cofilin_ADF PF00241.15 EIM86005.1 - 1.7e-42 144.2 0.6 1.9e-42 144.1 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Porin_3 PF01459.17 EIM86007.1 - 9.2e-67 225.2 0.6 1e-66 225.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhodanese PF00581.15 EIM86008.1 - 9.3e-12 45.2 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain zf-RING_6 PF14835.1 EIM86010.1 - 6.7e-06 25.7 7.3 6.7e-06 25.7 5.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EIM86010.1 - 8.5e-05 22.3 13.3 8.5e-05 22.3 9.2 3.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM86010.1 - 0.0001 22.2 14.3 0.0001 22.2 9.9 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM86010.1 - 0.00046 19.7 10.7 0.00046 19.7 7.4 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM86010.1 - 0.00061 19.4 9.3 0.00061 19.4 6.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM86010.1 - 0.0029 17.2 10.9 0.0029 17.2 7.5 3.3 5 0 0 5 5 5 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIM86010.1 - 1.4 9.0 10.1 0.12 12.4 2.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger RESP18 PF14948.1 EIM86011.1 - 4.9 7.2 6.2 25 4.9 1.7 2.8 2 1 1 3 3 3 0 RESP18 domain DUF202 PF02656.10 EIM86012.1 - 4.8e-19 68.3 2.7 4.8e-19 68.3 1.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) UPF0233 PF06781.7 EIM86012.1 - 0.071 12.7 0.5 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF605 PF04652.11 EIM86012.1 - 0.44 9.8 2.7 0.52 9.6 1.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF3784 PF12650.2 EIM86012.1 - 0.85 9.5 4.7 1.7 8.6 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Kelch_4 PF13418.1 EIM86013.1 - 3.9e-24 84.1 4.2 1.1e-05 25.0 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EIM86013.1 - 1.3e-22 79.0 0.1 3.4e-06 26.4 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EIM86013.1 - 1.8e-20 72.1 2.9 0.00011 22.1 0.1 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EIM86013.1 - 1.3e-19 69.8 11.2 7.4e-08 32.3 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EIM86013.1 - 5.4e-16 58.1 2.3 0.00016 21.5 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIM86013.1 - 8.2e-16 57.0 7.8 0.00033 20.3 0.1 5.4 6 1 0 6 6 6 3 Kelch motif Pyridox_oxidase PF01243.15 EIM86014.1 - 1.2e-22 79.7 0.0 1.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EIM86014.1 - 4.2e-18 64.5 1.1 7.5e-18 63.7 0.7 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EIM86014.1 - 7.3e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glycolytic PF00274.14 EIM86015.1 - 4.7e-67 225.8 0.0 5.6e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF2376 PF09550.5 EIM86016.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) Linker_histone PF00538.14 EIM86017.1 - 4.2e-05 23.5 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family FKBP_C PF00254.23 EIM86019.1 - 5.7e-30 103.1 0.0 6.5e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ecl1 PF12855.2 EIM86021.1 - 5.9e-06 25.4 0.1 0.0047 16.1 0.1 2.3 2 0 0 2 2 2 2 Life-span regulatory factor zf-MYND PF01753.13 EIM86021.1 - 0.1 12.4 1.4 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 MYND finger Ribosomal_S30 PF04758.9 EIM86022.1 - 0.15 11.8 0.4 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein S30 Sec1 PF00995.18 EIM86024.1 - 9.6e-80 268.8 0.0 1.2e-79 268.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.7 EIM86025.1 - 5e-67 225.7 2.3 1e-66 224.7 1.1 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIM86025.1 - 2.8e-30 104.1 0.2 2.8e-30 104.1 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1805 PF08827.6 EIM86025.1 - 0.1 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) CHAT PF12770.2 EIM86026.1 - 5e-23 81.6 0.1 5.6e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 CHAT domain CENP-F_leu_zip PF10473.4 EIM86027.1 - 0.014 15.2 9.2 0.028 14.2 3.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.1 EIM86027.1 - 0.02 14.7 0.8 0.02 14.7 0.6 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.7 EIM86027.1 - 2.3 7.9 16.7 1 9.1 3.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 EIM86027.1 - 2.4 7.3 19.1 3.1 6.9 12.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EIM86027.1 - 2.6 7.9 7.9 2 8.2 1.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EIM86027.1 - 2.6 7.7 11.4 3 7.5 5.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EIM86027.1 - 3.3 6.6 15.6 7.3 5.5 9.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2985 PF11204.3 EIM86028.1 - 2.9e-29 100.6 3.5 5.3e-29 99.8 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) COX14 PF14880.1 EIM86029.1 - 0.049 13.2 0.7 0.15 11.6 0.5 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DLH PF01738.13 EIM86030.1 - 2.7e-23 82.3 0.0 4.7e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM86030.1 - 3.8e-09 36.4 0.0 6.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM86030.1 - 2.5e-07 30.8 0.0 5.3e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM86030.1 - 0.0026 17.3 0.0 1 8.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold CRAL_TRIO PF00650.15 EIM86031.1 - 5.9e-27 94.1 0.0 8.2e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM86031.1 - 3.1e-05 24.0 0.1 6.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIM86031.1 - 0.038 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain HEAT_2 PF13646.1 EIM86033.1 - 2.4e-48 162.3 5.3 2.1e-16 59.9 0.1 4.1 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 EIM86033.1 - 8.3e-23 78.5 0.0 0.0013 19.0 0.0 6.4 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 EIM86033.1 - 8.8e-14 50.2 0.4 0.017 15.1 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EIM86033.1 - 3.6e-09 36.8 4.1 0.01 16.3 0.1 5.7 4 2 1 5 5 5 2 HEAT-like repeat Arm PF00514.18 EIM86033.1 - 2.4e-05 23.9 0.1 0.033 13.9 0.1 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 EIM86033.1 - 0.018 15.1 0.0 1.3 9.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) IBN_N PF03810.14 EIM86033.1 - 0.13 12.1 0.1 4.6 7.2 0.0 3.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain Ribosomal_L10 PF00466.15 EIM86034.1 - 8e-19 67.4 0.0 1.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Cu-oxidase_3 PF07732.10 EIM86036.1 - 9e-36 122.1 1.4 4.7e-33 113.4 0.2 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM86036.1 - 1.8e-24 85.7 6.3 2.8e-20 72.2 0.4 4.1 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EIM86036.1 - 2.4e-23 82.7 0.3 1.5e-22 80.1 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Acetyltransf_3 PF13302.1 EIM86037.1 - 8.1e-26 90.8 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM86037.1 - 6.9e-14 52.0 0.0 8.4e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM86037.1 - 4.9e-13 48.9 0.1 7.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM86037.1 - 1.7e-06 28.1 0.1 2.6e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM86037.1 - 9.2e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM86037.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM86037.1 - 0.0057 16.3 0.0 0.0096 15.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Cyclase PF04199.8 EIM86037.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative cyclase F-box-like PF12937.2 EIM86038.1 - 3.5e-05 23.4 0.5 7.3e-05 22.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EIM86038.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.28 EIM86038.1 - 0.081 12.6 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EIM86038.1 - 2.1 8.0 5.4 5.9 6.6 0.4 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SSrecog PF03531.9 EIM86039.1 - 2.6e-71 239.5 0.2 8.6e-71 237.7 0.2 1.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EIM86039.1 - 9.3e-23 80.0 0.0 7.2e-21 73.9 0.0 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3966 PF13110.1 EIM86039.1 - 0.015 15.0 0.5 0.015 15.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) CHAT PF12770.2 EIM86040.1 - 7.6e-33 113.8 0.0 1.6e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 CHAT domain PP2C PF00481.16 EIM86041.1 - 5.8e-80 268.3 0.0 1.3e-79 267.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIM86041.1 - 0.00036 19.9 0.0 0.0014 18.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_hydro_71 PF03659.9 EIM86043.1 - 1.5e-95 319.9 8.5 2.4e-95 319.2 5.9 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 CS PF04969.11 EIM86044.1 - 2.7e-09 37.4 0.0 2.3e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 CS domain Sugar_tr PF00083.19 EIM86045.1 - 1.9e-89 300.3 23.3 2.2e-89 300.1 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM86045.1 - 1.4e-34 119.3 47.8 7.8e-32 110.3 17.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM86045.1 - 3.4e-11 42.0 1.4 3.4e-11 42.0 1.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EIM86045.1 - 0.25 9.3 10.0 0.24 9.4 2.2 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BUD22 PF09073.5 EIM86046.1 - 3.4e-59 201.0 25.7 4.1e-59 200.7 17.8 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.9 EIM86046.1 - 0.046 11.7 8.1 0.071 11.1 5.6 1.3 1 0 0 1 1 1 0 CDC45-like protein APG6 PF04111.7 EIM86046.1 - 0.38 9.7 4.5 0.73 8.8 3.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EIM86046.1 - 3 6.6 9.9 5.3 5.9 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TFCD_C PF12612.3 EIM86047.1 - 8.5e-35 119.9 0.0 1.2e-33 116.1 0.0 2.9 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EIM86047.1 - 1.2e-05 25.4 2.6 0.45 10.8 0.0 5.3 3 1 1 4 4 4 2 HEAT repeats Adaptin_N PF01602.15 EIM86047.1 - 0.0082 14.5 3.6 13 3.9 0.0 4.4 4 1 0 5 5 5 2 Adaptin N terminal region HEAT PF02985.17 EIM86047.1 - 0.011 15.7 16.7 0.11 12.6 0.0 6.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.1 EIM86047.1 - 0.053 14.0 8.4 0.57 10.7 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat ATP-synt_ab PF00006.20 EIM86048.1 - 8.9e-62 208.3 0.0 1.2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIM86048.1 - 1.5e-16 60.8 0.0 3.3e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIM86048.1 - 3.1e-11 43.3 0.5 5.5e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIM86048.1 - 0.00064 19.5 0.3 0.0014 18.4 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Tcp11 PF05794.8 EIM86050.1 - 1.4e-39 136.1 0.0 1.3e-25 90.0 0.0 3.5 3 1 0 3 3 3 3 T-complex protein 11 F-box-like PF12937.2 EIM86051.1 - 4.8e-08 32.5 0.4 3.6e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like AA_permease PF00324.16 EIM86052.1 - 5.4e-112 374.5 40.2 6.6e-112 374.2 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM86052.1 - 3.9e-34 117.9 48.2 4.8e-34 117.6 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EIM86052.1 - 0.011 15.8 0.4 0.011 15.8 0.3 3.3 4 0 0 4 4 4 0 PrgI family protein G-patch PF01585.18 EIM86053.1 - 7.6e-06 25.6 0.2 7.2e-05 22.4 0.2 2.3 2 0 0 2 2 2 1 G-patch domain Pex14_N PF04695.8 EIM86053.1 - 1.2 9.1 14.8 3.4 7.7 1.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.2 EIM86054.1 - 4.6e-11 42.2 0.9 1.3e-10 40.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM86054.1 - 0.12 12.0 2.3 0.62 9.7 0.2 3.2 2 1 0 2 2 2 0 F-box domain FlxA PF14282.1 EIM86054.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.0 3 0 0 3 3 3 0 FlxA-like protein PQ-loop PF04193.9 EIM86055.1 - 9.4e-36 121.1 12.5 3.4e-21 74.5 1.2 3.2 2 1 1 3 3 3 2 PQ loop repeat NfeD PF01957.13 EIM86055.1 - 2.3 8.3 6.2 32 4.6 0.0 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Band_7 PF01145.20 EIM86056.1 - 1.1e-20 74.2 0.8 1.5e-20 73.8 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_V PF00488.16 EIM86057.1 - 5.8e-52 176.4 0.0 1.4e-51 175.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIM86057.1 - 1.2e-35 123.1 0.8 5.1e-35 121.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EIM86057.1 - 0.0027 17.8 0.2 0.0082 16.2 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV F-box-like PF12937.2 EIM86058.1 - 8.6e-07 28.5 4.3 8.6e-07 28.5 3.0 3.4 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 EIM86058.1 - 0.064 12.9 5.9 0.85 9.3 0.5 3.4 3 0 0 3 3 3 0 F-box domain Thi4 PF01946.12 EIM86059.1 - 4.5e-91 304.0 0.2 5.5e-91 303.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIM86059.1 - 1.9e-10 40.2 0.0 8.7e-09 34.7 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM86059.1 - 7.4e-07 28.4 0.2 2.6e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIM86059.1 - 2.9e-06 27.2 0.1 7.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM86059.1 - 1.6e-05 24.7 1.0 0.0011 18.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM86059.1 - 1.9e-05 24.6 0.3 3.4e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM86059.1 - 4.4e-05 22.4 1.9 0.00048 19.1 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM86059.1 - 0.00024 21.2 0.2 0.00067 19.7 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM86059.1 - 0.00092 17.7 0.4 0.0017 16.9 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIM86059.1 - 0.009 15.1 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIM86059.1 - 0.028 13.2 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIM86059.1 - 0.11 11.1 0.2 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase zf-DHHC PF01529.15 EIM86060.1 - 7.1e-32 110.1 11.4 2.1e-31 108.6 7.9 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase CM_2 PF01817.16 EIM86061.1 - 9.1e-09 35.2 0.1 7.3e-05 22.7 0.0 3.4 2 1 0 2 2 2 2 Chorismate mutase type II DNase_NucA_NucB PF14040.1 EIM86062.1 - 9.4e-15 54.7 0.5 2.5e-14 53.4 0.4 1.7 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.1 EIM86063.1 - 1.9e-19 69.8 0.3 2.9e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.1 EIM86065.1 - 2.6e-18 66.2 1.8 2.6e-18 66.2 1.3 1.8 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB SUKH_6 PF14568.1 EIM86066.1 - 4.9e-07 30.2 0.0 1.1e-06 29.0 0.0 1.7 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.5 EIM86066.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.1 EIM86066.1 - 0.0013 18.2 0.0 0.0069 15.8 0.0 2.1 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall ORC5_C PF14630.1 EIM86066.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DNase_NucA_NucB PF14040.1 EIM86067.1 - 1.2e-16 60.8 0.7 1.7e-16 60.3 0.5 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Chitin_bind_4 PF00379.18 EIM86067.1 - 0.061 13.5 0.3 0.085 13.1 0.2 1.3 1 0 0 1 1 1 0 Insect cuticle protein Epimerase PF01370.16 EIM86069.1 - 1.9e-20 73.3 0.0 2.4e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIM86069.1 - 3.1e-08 33.7 0.0 1.2e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EIM86069.1 - 1.7e-07 30.2 0.0 2.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM86069.1 - 5.9e-06 25.3 0.0 0.004 16.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIM86069.1 - 6.5e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EIM86069.1 - 0.02 14.5 0.5 0.11 12.1 0.4 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EIM86069.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding LacAB_rpiB PF02502.13 EIM86070.1 - 2.3e-43 147.1 0.0 2.7e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 EIM86070.1 - 0.068 13.0 0.7 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) F_bP_aldolase PF01116.15 EIM86071.1 - 3.8e-70 236.2 0.0 4.3e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.11 EIM86072.1 - 9.4e-34 116.6 27.5 9.4e-34 116.6 19.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EIM86073.1 - 3.4e-28 98.2 0.0 5.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86073.1 - 1.5e-05 24.7 12.4 2.9e-05 23.8 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.12 EIM86074.1 - 2.7e-104 348.2 0.6 3.7e-104 347.8 0.4 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIM86074.1 - 1.3e-39 135.6 2.2 2.1e-39 134.9 1.6 1.4 1 0 0 1 1 1 1 DAK2 domain DUF837 PF05769.6 EIM86075.1 - 9e-05 22.0 7.8 0.0053 16.3 3.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF837) Nsp1_C PF05064.8 EIM86075.1 - 0.019 14.6 0.5 0.019 14.6 0.4 2.0 2 1 0 2 2 2 0 Nsp1-like C-terminal region IFT57 PF10498.4 EIM86075.1 - 0.022 13.5 7.0 0.032 12.9 4.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0242 PF06785.6 EIM86075.1 - 0.56 8.8 6.8 0.89 8.1 4.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) HALZ PF02183.13 EIM86075.1 - 1.5 8.5 6.5 2.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper FdhE PF04216.7 EIM86075.1 - 3 7.4 5.4 4.5 6.9 3.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DivIC PF04977.10 EIM86075.1 - 6.3 6.3 11.5 0.13 11.7 1.2 3.0 4 0 0 4 4 4 0 Septum formation initiator ABM PF03992.11 EIM86076.1 - 1.4e-08 34.6 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FAD_binding_2 PF00890.19 EIM86077.1 - 1.1e-44 152.9 0.6 6.2e-39 134.0 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIM86077.1 - 3.7e-05 22.9 1.7 8.6e-05 21.7 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.19 EIM86077.1 - 0.00036 19.5 6.0 0.00036 19.5 4.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EIM86077.1 - 0.0004 19.3 4.6 0.012 14.5 0.0 3.2 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM86077.1 - 0.0017 18.3 0.3 0.0017 18.3 0.2 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM86077.1 - 0.0024 16.4 4.0 0.17 10.3 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 EIM86077.1 - 0.0054 16.8 0.0 0.18 11.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM86077.1 - 0.0066 16.3 8.1 0.32 10.8 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EIM86078.1 - 5.6e-23 81.6 3.0 3.8e-18 65.9 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86078.1 - 5.1e-20 72.2 1.6 1e-11 45.0 0.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM86078.1 - 2e-09 37.3 0.3 4.5e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIM86078.1 - 0.0017 18.4 0.2 0.0037 17.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIM86078.1 - 0.0053 17.1 0.1 0.065 13.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 EIM86078.1 - 0.025 13.8 0.6 0.048 12.9 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 EIM86078.1 - 0.027 14.4 0.3 0.052 13.5 0.2 1.5 1 1 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 EIM86078.1 - 0.08 13.3 0.3 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.17 EIM86079.1 - 2.3e-58 193.7 1.4 1.2e-18 66.4 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM86079.1 - 2.4e-47 158.7 0.3 1.3e-13 50.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM86079.1 - 1.4e-21 76.1 0.1 1.5e-05 24.7 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM86079.1 - 1.3e-07 31.2 0.0 0.15 11.8 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIM86079.1 - 2.5e-07 30.4 1.1 1.9 8.3 0.0 5.3 3 1 1 4 4 4 3 RNA binding motif TPR_19 PF14559.1 EIM86079.1 - 0.00076 19.7 3.9 0.0025 18.1 0.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86079.1 - 1.5 8.5 9.3 0.21 11.2 2.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 EIM86079.1 - 3.2 8.6 26.2 0.048 14.3 0.8 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat MSP1_C PF07462.6 EIM86082.1 - 6.3 5.0 5.4 10 4.3 3.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Basic PF01586.11 EIM86083.1 - 0.062 14.0 0.2 2.1 9.1 0.1 3.3 2 0 0 2 2 2 0 Myogenic Basic domain PX PF00787.19 EIM86084.1 - 5.5e-13 48.6 0.0 1.6e-10 40.7 0.2 3.1 2 1 0 2 2 2 1 PX domain PLDc_2 PF13091.1 EIM86084.1 - 4.2e-12 45.9 0.0 8.4e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIM86084.1 - 6e-12 44.9 1.3 9.6e-05 22.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.24 EIM86084.1 - 0.017 15.3 0.8 0.077 13.1 0.5 2.2 1 1 0 1 1 1 0 PH domain Rho_N PF07498.7 EIM86085.1 - 0.00017 21.3 0.1 0.00032 20.3 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 EIM86085.1 - 0.0017 17.7 0.7 0.0039 16.6 0.5 1.6 1 0 0 1 1 1 1 SAP domain PROCN PF08083.6 EIM86086.1 - 3.6e-217 720.6 8.5 1.4e-216 718.6 5.4 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EIM86086.1 - 1.1e-126 420.8 0.5 1.9e-126 420.0 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EIM86086.1 - 2.5e-92 306.4 1.2 5.6e-92 305.3 0.8 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EIM86086.1 - 3e-79 263.9 1.9 3e-79 263.9 1.3 2.7 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EIM86086.1 - 2e-69 231.4 0.1 3.8e-69 230.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EIM86086.1 - 3.1e-43 145.5 0.2 6.8e-43 144.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EIM86086.1 - 1.7e-35 121.4 0.0 3.6e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EIM86086.1 - 0.0089 15.7 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MATH PF00917.21 EIM86087.1 - 2.2e-05 24.6 0.2 4.6e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 MATH domain BTB PF00651.26 EIM86087.1 - 5e-05 23.2 0.0 0.13 12.2 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain BUD22 PF09073.5 EIM86087.1 - 0.23 10.4 7.0 0.37 9.8 4.8 1.2 1 0 0 1 1 1 0 BUD22 GRASP55_65 PF04495.9 EIM86088.1 - 8.7e-53 178.0 0.0 1.8e-36 125.1 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EIM86088.1 - 0.017 15.0 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Fungal_trans PF04082.13 EIM86090.1 - 7.9e-22 77.3 0.2 1.3e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86090.1 - 5.6e-07 29.3 9.3 1e-06 28.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 EIM86091.1 - 9.2e-17 61.1 0.2 1.8e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 ThiF family SKN1 PF03935.10 EIM86092.1 - 3.5e-206 685.2 7.6 3.9e-206 685.0 5.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Mur_ligase_M PF08245.7 EIM86093.1 - 1.2e-07 31.9 0.0 3.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_32 PF13679.1 EIM86094.1 - 2.9e-20 72.3 0.1 2.3e-18 66.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86094.1 - 0.0013 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM86094.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86094.1 - 0.13 12.8 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86094.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Endonuc-FokI_C PF09254.6 EIM86094.1 - 0.15 11.1 0.1 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal adh_short PF00106.20 EIM86095.1 - 4.6e-26 91.7 1.8 5.8e-26 91.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86095.1 - 9.1e-14 51.8 0.2 1.2e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM86095.1 - 2.1e-05 24.2 1.0 3.1e-05 23.6 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIM86095.1 - 0.041 13.5 1.2 0.059 13.0 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EIM86096.1 - 2.6e-50 171.3 0.0 3.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EIM86096.1 - 8.3e-15 53.3 0.0 6.8e-10 37.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EIM86096.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain OPT PF03169.10 EIM86097.1 - 9.5e-148 493.3 40.9 1.1e-147 493.1 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ADH_zinc_N PF00107.21 EIM86098.1 - 1.8e-22 79.2 0.0 2.7e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM86098.1 - 7.1e-13 49.5 0.0 1.4e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM86098.1 - 4e-12 45.8 0.0 9.6e-11 41.4 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 EIM86100.1 - 0.0063 16.2 0.1 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like AhpC-TSA PF00578.16 EIM86101.1 - 2.6e-28 98.2 0.0 3.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM86101.1 - 1.3e-18 66.9 0.0 1.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EIM86101.1 - 0.00084 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF4031 PF13223.1 EIM86101.1 - 0.0071 16.4 0.1 0.082 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4031) E1_dh PF00676.15 EIM86102.1 - 2.3e-84 282.6 0.0 2.7e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_C48 PF02902.14 EIM86103.1 - 6.3e-36 124.0 0.4 1.2e-20 74.1 0.1 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SMC_N PF02463.14 EIM86106.1 - 3e-29 101.8 0.0 8.9e-29 100.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIM86106.1 - 2.2e-17 64.0 5.0 2.2e-17 64.0 3.5 5.1 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 EIM86106.1 - 1.3e-07 31.8 0.2 0.019 14.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIM86106.1 - 0.00013 21.4 0.1 0.00056 19.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DMPK_coil PF08826.5 EIM86106.1 - 0.0012 18.6 0.9 0.0012 18.6 0.6 5.5 6 0 0 6 6 6 1 DMPK coiled coil domain like SbcCD_C PF13558.1 EIM86106.1 - 0.0015 18.3 0.0 0.0085 15.9 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EIM86106.1 - 0.19 12.0 0.1 0.19 12.0 0.0 5.9 4 2 0 4 4 4 0 ABC transporter AAA_15 PF13175.1 EIM86106.1 - 0.59 9.1 16.8 0.82 8.6 9.4 2.8 2 1 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 EIM86106.1 - 1.2 8.2 11.4 0.56 9.3 0.4 4.2 2 2 1 5 5 5 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EIM86106.1 - 3.9 7.3 26.9 9.9 5.9 4.4 5.9 2 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus OPT PF03169.10 EIM86107.1 - 7.7e-175 582.8 52.3 8.8e-175 582.6 36.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DIOX_N PF14226.1 EIM86108.1 - 1.7e-30 105.9 0.0 2.7e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM86108.1 - 1.6e-21 76.3 0.0 4.7e-21 74.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily OPT PF03169.10 EIM86109.1 - 1.4e-146 489.5 47.2 1.6e-146 489.3 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 EIM86111.1 - 9.9e-15 54.8 0.5 8.7e-13 48.5 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86111.1 - 8.4e-09 35.5 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM86111.1 - 0.00016 21.3 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1324 PF07038.6 EIM86111.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) OPT PF03169.10 EIM86112.1 - 1.7e-186 621.3 53.9 2e-186 621.1 37.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 EIM86115.1 - 6.5e-69 231.9 0.0 1.1e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86115.1 - 5.4e-49 166.6 0.0 1.3e-48 165.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM86115.1 - 0.0029 16.6 0.0 0.0089 15.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like TH1 PF04858.8 EIM86115.1 - 0.16 10.0 0.2 0.27 9.3 0.2 1.3 1 0 0 1 1 1 0 TH1 protein DUF676 PF05057.9 EIM86116.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EIM86116.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIM86116.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SKG6 PF08693.5 EIM86117.1 - 0.12 11.7 0.2 0.32 10.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-Tim10_DDP PF02953.10 EIM86119.1 - 4.4e-19 67.5 7.9 5.7e-19 67.1 5.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1178 PF06676.6 EIM86119.1 - 0.017 15.3 0.4 0.064 13.4 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Mmp37 PF09139.6 EIM86119.1 - 0.044 12.8 0.2 0.045 12.7 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DAHP_synth_1 PF00793.15 EIM86120.1 - 1.7e-88 295.8 0.0 2.1e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2188 PF09954.4 EIM86121.1 - 0.092 12.6 1.2 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Pol_alpha_B_N PF08418.5 EIM86121.1 - 0.35 10.3 3.3 0.33 10.4 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NifU PF01106.12 EIM86124.1 - 0.0029 17.3 0.3 0.83 9.4 0.1 2.6 2 0 0 2 2 2 2 NifU-like domain TFIIA PF03153.8 EIM86124.1 - 0.96 9.2 7.3 1.1 9.1 5.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pol_alpha_B_N PF08418.5 EIM86124.1 - 0.96 8.9 9.0 1.5 8.2 6.2 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ashwin PF15323.1 EIM86124.1 - 2.7 7.9 11.9 4 7.3 8.2 1.2 1 0 0 1 1 1 0 Developmental protein Macoilin PF09726.4 EIM86124.1 - 8.8 4.4 16.7 11 4.1 11.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SAM_2 PF07647.12 EIM86125.1 - 1.8e-09 37.3 0.1 8.5e-09 35.1 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIM86125.1 - 2.4e-05 24.4 0.1 6.7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) OPT PF03169.10 EIM86127.1 - 2.9e-147 491.7 44.8 3.3e-147 491.5 31.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_5 PF12695.2 EIM86128.1 - 1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM86128.1 - 3.4e-06 27.0 0.3 6e-06 26.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM86128.1 - 0.0056 16.2 0.1 0.39 10.2 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86128.1 - 0.01 15.0 0.3 0.13 11.4 0.2 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1749 PF08538.5 EIM86128.1 - 0.027 13.3 0.2 0.046 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF915 PF06028.6 EIM86128.1 - 0.04 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.16 EIM86129.1 - 1.4e-49 168.3 0.0 1.4e-49 168.3 0.0 3.1 3 1 0 3 3 3 2 Ribosomal protein L1p/L10e family Abhydrolase_6 PF12697.2 EIM86130.1 - 5.6e-08 32.9 1.2 7.6e-08 32.5 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM86130.1 - 1.6e-07 31.2 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EIM86130.1 - 0.012 14.9 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EIM86130.1 - 0.018 14.2 0.1 0.13 11.4 0.1 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EIM86130.1 - 0.082 12.4 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M64 PF09471.5 EIM86132.1 - 2.1e-25 89.8 0.0 3.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 DUF4610 PF15384.1 EIM86133.1 - 2.2 7.7 6.8 0.73 9.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4610) RNA_pol_Rpb4 PF03874.11 EIM86135.1 - 1e-19 70.6 0.3 1.4e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Prenyltrans PF00432.16 EIM86136.1 - 2.7e-23 81.1 20.9 1.9e-07 30.5 1.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIM86136.1 - 8.6e-18 64.7 0.1 1.7e-11 44.4 0.0 4.0 2 2 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIM86136.1 - 0.0052 16.7 0.0 0.12 12.4 0.0 2.6 2 1 1 3 3 3 2 Prenyltransferase-like Mito_fiss_reg PF05308.6 EIM86136.1 - 0.16 11.3 11.0 0.3 10.4 7.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.20 EIM86138.1 - 2.2e-09 36.8 0.0 5.9e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86138.1 - 0.032 13.2 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EIM86139.1 - 4.4e-10 39.1 0.0 1.3e-08 34.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86139.1 - 0.0083 15.2 0.0 0.36 9.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase DUF4220 PF13968.1 EIM86141.1 - 0.38 9.8 0.6 0.59 9.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Pkinase PF00069.20 EIM86142.1 - 5.3e-09 35.5 0.0 1.7e-07 30.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86142.1 - 0.16 11.0 0.0 0.66 8.9 0.0 2.0 2 1 1 3 3 3 0 Protein tyrosine kinase Pkinase PF00069.20 EIM86143.1 - 2.4e-10 40.0 0.0 3.5e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86143.1 - 0.0015 17.6 0.1 0.016 14.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EIM86144.1 - 4.7e-09 35.7 0.0 1.2e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain DUF972 PF06156.8 EIM86145.1 - 0.76 10.1 11.8 0.44 10.9 4.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 EIM86145.1 - 0.98 9.1 8.8 0.27 10.9 2.1 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain zf-C2H2_4 PF13894.1 EIM86147.1 - 0.023 15.0 12.2 0.89 10.0 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM86147.1 - 0.031 14.5 1.1 0.031 14.5 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type NOT2_3_5 PF04153.13 EIM86148.1 - 8.4e-33 113.0 0.1 8.4e-33 113.0 0.1 2.1 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family HMG_box PF00505.14 EIM86149.1 - 1.1e-09 38.4 0.1 3.1e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM86149.1 - 0.0024 18.1 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF904 PF06005.7 EIM86149.1 - 0.083 13.1 3.5 0.16 12.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HMG_box PF00505.14 EIM86150.1 - 1.6e-12 47.4 7.1 6.3e-12 45.5 4.9 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM86150.1 - 2.6e-06 27.7 2.1 3.7e-06 27.2 1.5 1.3 1 0 0 1 1 1 1 HMG-box domain mRNA_stabil PF13929.1 EIM86150.1 - 0.072 12.0 0.1 0.076 11.9 0.1 1.0 1 0 0 1 1 1 0 mRNA stabilisation zf-C2H2 PF00096.21 EIM86152.1 - 0.0078 16.5 2.2 0.0078 16.5 1.5 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM86152.1 - 0.59 10.6 32.2 0.19 12.1 0.9 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger SSF PF00474.12 EIM86153.1 - 1.7e-14 53.3 30.1 1.7e-14 53.3 20.9 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Amidase PF01425.16 EIM86154.1 - 2.8e-95 319.7 0.0 3.4e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Amidase HMG_box PF00505.14 EIM86156.1 - 2.2e-07 31.0 0.0 6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box zf-MYND PF01753.13 EIM86158.1 - 2.3e-05 24.1 14.6 2.3e-05 24.1 10.1 1.9 2 0 0 2 2 2 1 MYND finger ENTH PF01417.15 EIM86159.1 - 9.9e-46 154.6 0.2 1.5e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIM86159.1 - 0.011 14.4 0.1 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 ANTH domain SHD1 PF03983.7 EIM86160.1 - 0.045 13.4 0.1 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 SLA1 homology domain 1, SHD1 SHD1 PF03983.7 EIM86161.1 - 0.045 13.4 0.1 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 SLA1 homology domain 1, SHD1 Pkinase PF00069.20 EIM86162.1 - 7.3e-09 35.1 0.0 3.4e-07 29.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Glyco_hydro_20 PF00728.17 EIM86163.1 - 2.3e-85 286.8 0.0 2.9e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIM86163.1 - 1.7e-15 57.8 0.0 3.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIM86163.1 - 8.9e-09 35.9 0.1 1.9e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_M36 PF02128.10 EIM86164.1 - 7.5e-111 370.5 6.3 1.1e-110 370.0 4.4 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) GSIII_N PF12437.3 EIM86164.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Peptidase_M4_C PF02868.10 EIM86164.1 - 0.01 15.6 0.0 0.053 13.2 0.0 2.2 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.8 EIM86164.1 - 0.023 14.1 0.1 0.054 12.9 0.1 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif ATP-synt_C PF00137.16 EIM86165.1 - 7.4e-27 93.0 32.3 1.5e-18 66.4 8.6 3.2 3 0 0 3 3 3 2 ATP synthase subunit C DUF2970 PF11174.3 EIM86165.1 - 0.064 12.8 0.6 0.064 12.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Aldedh PF00171.17 EIM86167.1 - 9.5e-120 400.0 0.0 1.1e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family dsrm PF00035.20 EIM86169.1 - 0.00021 21.8 0.1 0.0003 21.2 0.1 1.4 1 1 0 1 1 1 1 Double-stranded RNA binding motif Aldedh PF00171.17 EIM86170.1 - 1.4e-119 399.4 0.0 1.6e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycos_transf_1 PF00534.15 EIM86171.1 - 2e-23 82.6 0.0 3.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIM86171.1 - 1e-08 35.4 0.1 2.7e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPMT PF05724.6 EIM86174.1 - 2.4e-34 118.6 0.0 2.7e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EIM86174.1 - 4e-10 40.2 0.0 5.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM86174.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86174.1 - 3.7e-08 33.7 0.0 5.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86174.1 - 7.9e-08 32.5 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86174.1 - 2e-07 31.4 0.0 2.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM86174.1 - 5.2e-07 29.7 0.0 9.4e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM86174.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 EIM86177.1 - 0.00015 21.5 2.7 0.047 13.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3312 PF11768.3 EIM86177.1 - 0.47 8.6 0.0 1.5 6.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Sporozoite_P67 PF05642.6 EIM86177.1 - 6.2 4.5 12.2 13 3.5 8.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glucosamine_iso PF01182.15 EIM86178.1 - 5e-23 81.8 0.0 7.6e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FMN_dh PF01070.13 EIM86179.1 - 1.6e-113 379.1 0.1 2.3e-113 378.6 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EIM86179.1 - 1.6e-07 30.6 0.1 0.02 13.9 0.0 3.0 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EIM86179.1 - 2.2e-05 23.5 0.1 3.3e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIM86179.1 - 0.00029 19.8 0.1 0.0022 16.9 0.0 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIM86179.1 - 0.0099 15.0 0.3 0.018 14.1 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase TPR_10 PF13374.1 EIM86180.1 - 1.8e-161 520.2 0.0 1.3e-12 47.2 0.0 13.1 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.1 EIM86180.1 - 1.9e-160 521.1 13.4 6e-17 61.3 0.0 9.7 1 1 9 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86180.1 - 2.7e-52 170.4 10.3 0.0024 17.5 0.0 13.3 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_17 PF13431.1 EIM86180.1 - 1.7e-36 121.3 6.5 0.38 11.0 0.0 13.2 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.12 EIM86180.1 - 4.8e-34 113.5 2.7 0.87 9.6 0.0 13.0 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86180.1 - 1.2e-33 115.2 0.0 0.045 14.1 0.0 12.6 3 3 10 13 13 13 9 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86180.1 - 4.6e-32 108.2 8.1 0.6 9.8 0.0 13.1 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86180.1 - 7.3e-25 87.0 0.0 0.031 14.9 0.1 11.0 5 2 8 13 13 13 6 Tetratricopeptide repeat DUF4074 PF13293.1 EIM86180.1 - 1.1e-23 83.2 4.1 5 7.4 0.0 12.8 13 0 0 13 13 13 5 Domain of unknown function (DUF4074) TPR_4 PF07721.9 EIM86180.1 - 2.2e-21 74.0 0.0 1.4 9.5 0.0 12.6 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86180.1 - 3.4e-18 65.0 4.7 0.18 11.4 0.0 10.5 5 2 7 12 12 12 6 TPR repeat TPR_14 PF13428.1 EIM86180.1 - 1.7e-16 59.2 8.6 32 5.5 0.0 12.4 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM86180.1 - 1e-15 56.1 17.0 15 5.6 0.0 12.2 13 0 0 13 13 13 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM86180.1 - 1.5e-14 53.8 0.0 1.4 9.1 0.0 8.9 1 1 11 12 12 12 3 Anaphase-promoting complex, cyclosome, subunit 3 Rab5-bind PF09311.6 EIM86180.1 - 1.3e-12 48.0 15.2 4.2 7.2 1.0 11.1 1 1 11 12 12 12 1 Rabaptin-like protein PPR PF01535.15 EIM86180.1 - 1.4e-11 43.5 1.2 33 4.7 0.0 11.7 13 0 0 13 13 13 0 PPR repeat zf-Mss51 PF13824.1 EIM86180.1 - 2e-07 30.7 1.0 12 5.8 0.0 6.8 9 0 0 9 9 5 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF814 PF05670.8 EIM86180.1 - 3.5e-07 30.0 8.0 6.4 6.7 0.0 9.5 1 1 8 10 10 10 1 Domain of unknown function (DUF814) TPR_6 PF13174.1 EIM86180.1 - 1.3e-05 25.3 29.2 37 5.0 0.1 12.2 13 0 0 13 13 11 0 Tetratricopeptide repeat Metallophos_3 PF14582.1 EIM86180.1 - 2.6e-05 23.5 1.5 13 4.8 0.0 5.9 3 2 2 7 7 7 0 Metallophosphoesterase, calcineurin superfamily PPR_2 PF13041.1 EIM86180.1 - 0.002 18.0 5.2 78 3.3 0.0 8.1 10 0 0 10 10 10 0 PPR repeat family COPR5 PF15340.1 EIM86180.1 - 0.015 15.6 0.5 38 4.6 0.0 3.9 2 2 2 5 5 5 0 Cooperator of PRMT5 family DUF4363 PF14276.1 EIM86180.1 - 0.46 10.2 14.0 33 4.1 0.1 6.7 9 0 0 9 9 8 0 Domain of unknown function (DUF4363) FMN_dh PF01070.13 EIM86182.1 - 0.0069 15.2 0.0 0.015 14.1 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase FMN_dh PF01070.13 EIM86183.1 - 3.7e-93 312.2 0.1 4.6e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EIM86183.1 - 1.3e-07 30.9 0.1 0.026 13.5 0.0 3.4 4 0 0 4 4 4 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EIM86183.1 - 0.00024 20.1 0.1 0.00037 19.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIM86183.1 - 0.00027 19.9 0.1 0.0018 17.2 0.0 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIM86183.1 - 0.0046 16.1 0.2 0.01 15.0 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase TPR_10 PF13374.1 EIM86184.1 - 2.7e-158 510.1 0.0 1.4e-10 40.6 0.0 14.2 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_12 PF13424.1 EIM86184.1 - 2.4e-137 447.1 5.0 1.2e-16 60.3 0.0 10.2 4 2 8 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86184.1 - 8.7e-53 172.0 16.8 0.009 15.7 0.0 14.3 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86184.1 - 3.5e-34 115.0 5.8 0.21 11.2 0.0 14.1 14 0 0 14 14 14 10 Tetratricopeptide repeat TPR_17 PF13431.1 EIM86184.1 - 3e-33 111.2 3.7 0.82 10.0 0.0 14.1 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.12 EIM86184.1 - 1.5e-31 105.7 12.0 0.92 9.5 0.0 14.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_4 PF07721.9 EIM86184.1 - 2.8e-28 95.3 0.0 0.059 13.8 0.0 13.6 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86184.1 - 6.4e-25 87.2 0.0 0.16 12.3 0.0 12.2 9 3 4 13 13 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86184.1 - 3.1e-23 81.8 0.0 0.17 12.6 0.1 12.8 11 3 3 14 14 14 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86184.1 - 2.9e-21 74.9 0.4 0.00099 18.7 0.0 11.8 9 3 3 12 12 12 3 TPR repeat TPR_14 PF13428.1 EIM86184.1 - 1.1e-18 65.9 10.1 8 7.4 0.1 13.5 13 1 1 14 14 14 0 Tetratricopeptide repeat DUF4074 PF13293.1 EIM86184.1 - 1.1e-13 51.1 7.1 5.5 7.2 0.0 12.4 14 0 0 14 14 14 1 Domain of unknown function (DUF4074) TPR_8 PF13181.1 EIM86184.1 - 3.4e-13 48.3 15.0 9.7 6.2 0.0 12.7 13 0 0 13 13 13 0 Tetratricopeptide repeat PPR PF01535.15 EIM86184.1 - 4.5e-12 45.0 9.8 4.8 7.3 0.0 12.0 14 0 0 14 14 13 1 PPR repeat Apc3 PF12895.2 EIM86184.1 - 2.8e-11 43.3 0.0 6.3 7.0 0.0 9.1 1 1 10 12 12 12 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIM86184.1 - 1.8e-06 27.9 28.6 1.9 9.1 0.0 13.1 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_3 PF07720.7 EIM86184.1 - 1.2e-05 24.9 0.0 78 3.2 0.0 8.5 12 0 0 12 12 12 0 Tetratricopeptide repeat Metallophos_3 PF14582.1 EIM86184.1 - 0.00097 18.3 0.4 2.3 7.3 0.0 4.8 3 2 4 8 8 8 1 Metallophosphoesterase, calcineurin superfamily DUF1924 PF09086.6 EIM86184.1 - 0.0048 16.9 0.2 12 6.0 0.0 4.3 4 2 0 4 4 4 0 Domain of unknown function (DUF1924) DUF832 PF05734.6 EIM86184.1 - 0.035 13.3 0.1 5 6.2 0.0 3.7 3 1 1 4 4 4 0 Herpesvirus protein of unknown function (DUF832) DUF1962 PF09227.5 EIM86184.1 - 9.4 6.3 9.7 55 3.9 0.0 6.2 9 0 0 9 9 7 0 Domain of unknown function (DUF1962) AAA PF00004.24 EIM86185.1 - 1.5e-38 131.9 0.0 2.2e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM86185.1 - 7e-08 31.7 0.0 6e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIM86185.1 - 2.4e-06 27.6 0.1 0.00089 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIM86185.1 - 3.1e-06 28.0 0.0 1.7e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM86185.1 - 4.2e-06 26.9 0.1 0.00027 21.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIM86185.1 - 7.8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIM86185.1 - 7.2e-05 22.5 0.3 0.00048 19.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM86185.1 - 8e-05 22.6 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIM86185.1 - 0.00011 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM86185.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EIM86185.1 - 0.00022 20.4 0.1 0.0014 17.8 0.1 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIM86185.1 - 0.0003 20.2 0.5 0.031 13.6 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EIM86185.1 - 0.00039 20.4 0.0 0.0014 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIM86185.1 - 0.00074 18.9 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIM86185.1 - 0.0008 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIM86185.1 - 0.001 19.1 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EIM86185.1 - 0.0015 18.2 0.1 0.01 15.5 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Rad17 PF03215.10 EIM86185.1 - 0.0018 17.0 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EIM86185.1 - 0.0021 17.7 0.0 0.11 12.1 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EIM86185.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 EIM86185.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIM86185.1 - 0.0028 16.4 0.1 0.0048 15.6 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 EIM86185.1 - 0.0093 15.4 0.0 0.037 13.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 EIM86185.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EIM86185.1 - 0.013 15.8 0.1 0.064 13.5 0.1 2.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EIM86185.1 - 0.024 14.3 0.1 0.073 12.8 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain UPF0079 PF02367.12 EIM86185.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EIM86185.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EIM86185.1 - 0.034 13.0 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EIM86185.1 - 0.045 13.1 0.2 1.6 8.1 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain AAA_21 PF13304.1 EIM86185.1 - 0.049 13.6 0.5 7.7 6.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain SKI PF01202.17 EIM86185.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.6 EIM86185.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIM86185.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EIM86185.1 - 0.085 11.9 0.0 0.47 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC SMC_N PF02463.14 EIM86185.1 - 0.16 11.1 0.0 7.1 5.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.20 EIM86185.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 EIM86185.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Peptidase_S24 PF00717.18 EIM86186.1 - 1.5e-11 43.7 0.1 2.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EIM86186.1 - 5.8e-06 25.8 0.0 0.012 15.1 0.0 3.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Pyr_redox_2 PF07992.9 EIM86187.1 - 1.8e-26 93.2 0.1 2.4e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM86187.1 - 5.7e-16 58.6 0.0 4.9e-14 52.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM86187.1 - 8.5e-07 29.2 0.2 0.0026 17.8 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM86187.1 - 0.00018 20.4 2.6 0.11 11.3 0.1 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM86187.1 - 0.00039 20.3 0.3 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM86187.1 - 0.0008 18.4 0.1 0.61 8.9 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM86187.1 - 0.0012 17.9 0.0 0.015 14.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EIM86187.1 - 0.009 14.8 1.6 0.094 11.5 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EIM86187.1 - 0.0099 15.9 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIM86187.1 - 0.016 15.4 0.0 0.15 12.3 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.1 EIM86187.1 - 0.017 14.0 0.0 0.94 8.3 0.0 2.6 1 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EIM86187.1 - 0.042 12.9 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM86187.1 - 0.062 12.3 0.3 1.1 8.2 0.0 2.5 2 1 1 3 3 3 0 FAD binding domain ApbA PF02558.11 EIM86187.1 - 0.081 12.3 0.4 3 7.2 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIM86187.1 - 0.14 10.6 0.3 1.6 7.1 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Glyco_hydro_20 PF00728.17 EIM86188.1 - 2.1e-83 280.4 0.0 3.4e-83 279.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIM86188.1 - 1.2e-14 55.0 0.0 2.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIM86188.1 - 6.5e-10 39.6 0.2 1.3e-08 35.3 0.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Tet_res_leader PF08050.7 EIM86189.1 - 1.2 8.8 3.6 12 5.5 0.2 2.3 2 0 0 2 2 2 0 Tetracycline resistance leader peptide BDHCT PF08072.6 EIM86190.1 - 0.12 12.4 0.3 4.3 7.5 0.1 2.6 2 0 0 2 2 2 0 BDHCT (NUC031) domain OppC_N PF12911.2 EIM86191.1 - 0.045 13.1 1.0 0.089 12.1 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1616 PF07760.6 EIM86191.1 - 0.059 12.4 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Fer4_5 PF12801.2 EIM86193.1 - 1.5 8.6 4.4 3.2 7.6 3.1 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain CopD PF05425.8 EIM86197.1 - 0.025 14.7 0.2 0.035 14.3 0.2 1.4 1 1 0 1 1 1 0 Copper resistance protein D TrbC PF04956.8 EIM86197.1 - 0.05 13.6 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF4381 PF14316.1 EIM86197.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PXPV PF12778.2 EIM86197.1 - 0.4 10.4 6.7 0.6 9.8 4.7 1.2 1 0 0 1 1 1 0 PXPV repeat (3 copies) Tetraspannin PF00335.15 EIM86198.1 - 9.2e-08 31.6 13.9 4e-07 29.5 9.6 1.9 1 1 0 1 1 1 1 Tetraspanin family DBINO PF13892.1 EIM86198.1 - 0.085 12.8 1.2 0.14 12.1 0.8 1.2 1 0 0 1 1 1 0 DNA-binding domain ABC2_membrane_2 PF12679.2 EIM86198.1 - 0.41 9.4 8.2 0.77 8.5 5.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein NfeD PF01957.13 EIM86198.1 - 1.1 9.3 8.2 8.2 6.5 0.1 2.6 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Cir_N PF10197.4 EIM86198.1 - 2.3 8.3 6.5 4 7.5 4.5 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR COesterase PF00135.23 EIM86199.1 - 1.1e-95 321.3 0.0 4.3e-95 319.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86199.1 - 7.5e-05 22.3 0.1 0.00021 20.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86199.1 - 0.0021 17.3 0.1 0.004 16.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Trehalase PF01204.13 EIM86201.1 - 2.4e-110 369.5 1.9 1.2e-99 334.2 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EIM86201.1 - 1.5e-05 23.9 0.1 0.0019 16.9 0.0 2.1 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase COesterase PF00135.23 EIM86204.1 - 2.6e-100 336.6 0.0 4.8e-99 332.4 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86204.1 - 0.00091 18.8 0.1 0.0029 17.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86204.1 - 0.0016 17.7 0.2 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3419 PF11899.3 EIM86206.1 - 2.8e-128 427.8 0.0 3.7e-128 427.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EIM86206.1 - 6.5e-09 35.7 0.0 6.9e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86206.1 - 2.2e-07 31.2 0.0 0.0001 22.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86206.1 - 3.6e-07 30.5 0.0 6.2e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86206.1 - 2.4e-05 24.8 0.0 0.0003 21.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM86206.1 - 7.5e-05 22.3 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM86206.1 - 0.00019 20.6 0.0 0.00086 18.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIM86206.1 - 0.00042 20.3 0.0 0.016 15.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86206.1 - 0.0029 17.9 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM86206.1 - 0.15 11.0 0.0 0.51 9.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase APH PF01636.18 EIM86207.1 - 9.3e-08 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family GSH_synth_ATP PF03917.12 EIM86208.1 - 8.3e-91 304.3 0.0 2.3e-90 302.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EIM86208.1 - 3.8e-32 110.5 0.0 8.5e-32 109.3 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase RPAP1_C PF08620.5 EIM86211.1 - 2.5e-19 68.9 0.0 4.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EIM86211.1 - 0.0015 18.1 1.6 0.003 17.1 1.1 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal TPR_10 PF13374.1 EIM86212.1 - 2.9e-100 325.7 0.1 3.6e-13 48.9 0.0 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EIM86212.1 - 5.4e-98 321.0 1.8 4.6e-15 55.3 0.0 6.5 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86212.1 - 5e-27 91.5 14.8 0.0096 15.6 0.0 8.6 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_4 PF07721.9 EIM86212.1 - 1.5e-20 71.4 1.1 0.079 13.4 0.4 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIM86212.1 - 2.2e-19 67.9 0.0 1.8 8.9 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIM86212.1 - 3.7e-18 63.9 4.8 2.5 8.2 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86212.1 - 5.6e-18 63.7 0.6 1.4 8.6 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86212.1 - 3.8e-16 59.2 0.0 0.75 10.5 1.0 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM86212.1 - 8.8e-15 53.8 1.7 3.4 8.5 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86212.1 - 4.9e-13 49.2 0.0 6.5 7.1 0.0 7.8 3 3 5 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM86212.1 - 5.2e-12 44.6 4.2 5.3 7.0 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF4074 PF13293.1 EIM86212.1 - 6.4e-12 45.5 0.2 3.5 7.9 0.0 7.3 8 0 0 8 8 7 1 Domain of unknown function (DUF4074) TPR_11 PF13414.1 EIM86212.1 - 5.1e-09 35.6 0.1 4.2 7.0 0.0 6.9 4 1 3 7 7 7 1 TPR repeat Rab5-bind PF09311.6 EIM86212.1 - 2.8e-07 30.5 0.1 8.7 6.2 0.0 5.9 1 1 5 6 6 6 0 Rabaptin-like protein PPR PF01535.15 EIM86212.1 - 6.6e-07 28.8 0.4 5.1 7.2 0.0 6.5 7 0 0 7 7 7 1 PPR repeat DUF3268 PF11672.3 EIM86212.1 - 0.00042 20.3 1.9 89 3.2 0.0 6.0 1 1 4 7 7 7 0 Protein of unknown function (DUF3268) Metallophos_3 PF14582.1 EIM86212.1 - 0.0019 17.3 0.0 0.72 8.9 0.0 3.8 2 1 3 5 5 5 1 Metallophosphoesterase, calcineurin superfamily DUF3105 PF11303.3 EIM86212.1 - 0.0021 17.9 0.4 25 4.7 0.0 4.7 1 1 2 5 5 5 0 Protein of unknown function (DUF3105) DUF1897 PF09005.5 EIM86212.1 - 0.0061 15.9 5.5 44 3.6 0.0 6.4 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) DNA_gyraseB_C PF00986.16 EIM86212.1 - 0.011 15.5 8.4 4 7.2 0.0 5.6 5 0 0 5 5 5 0 DNA gyrase B subunit, carboxyl terminus LEA_5 PF00477.12 EIM86212.1 - 0.05 13.8 7.0 12 6.1 0.1 4.8 1 1 4 5 5 5 0 Small hydrophilic plant seed protein TPR_6 PF13174.1 EIM86212.1 - 0.1 13.1 18.4 96 3.7 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat FlbD PF06289.6 EIM86212.1 - 0.12 11.7 0.4 42 3.6 0.0 3.9 3 0 0 3 3 3 0 Flagellar protein (FlbD) DUF3157 PF11355.3 EIM86212.1 - 0.19 10.9 11.4 1.6 7.9 0.2 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3157) DUF1343 PF07075.6 EIM86212.1 - 2.9 6.6 15.2 13 4.4 0.1 5.5 1 1 5 7 7 7 0 Protein of unknown function (DUF1343) DUF365 PF04033.7 EIM86212.1 - 5.2 7.1 6.1 26 4.9 0.1 3.7 4 1 1 5 5 4 0 Domain of unknown function (DUF365) DIOX_N PF14226.1 EIM86213.1 - 3.3e-29 101.7 0.0 5.7e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM86213.1 - 4.8e-19 68.4 0.0 1.1e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 EIM86214.1 - 2.1e-38 132.1 24.4 1.6e-37 129.2 16.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM86214.1 - 8.7e-23 80.5 28.8 6.2e-12 44.8 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2069 PF09842.4 EIM86214.1 - 0.3 11.0 4.2 0.37 10.7 0.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) HIT PF01230.18 EIM86215.1 - 3e-25 88.5 0.2 4e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIM86215.1 - 1.2e-11 44.8 0.2 1.6e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIM86215.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Phage_connect_1 PF05135.8 EIM86217.1 - 0.006 16.7 0.4 0.4 10.8 0.0 2.3 2 0 0 2 2 2 2 Phage gp6-like head-tail connector protein Cwf_Cwc_15 PF04889.7 EIM86218.1 - 0.037 13.7 0.6 0.053 13.2 0.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EF-1_beta_acid PF10587.4 EIM86218.1 - 0.27 11.4 3.4 0.73 10.0 2.4 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1793 PF08760.6 EIM86220.1 - 1.7e-23 83.3 1.9 4e-23 82.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 EIM86220.1 - 0.00039 19.6 2.7 0.00087 18.5 1.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EIM86220.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4328 PF14219.1 EIM86220.1 - 0.05 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Phage_Coat_B PF05356.6 EIM86220.1 - 0.055 13.1 1.9 0.17 11.5 1.3 1.9 1 0 0 1 1 1 0 Phage Coat protein B RRM_1 PF00076.17 EIM86221.1 - 4.4e-10 39.0 0.0 9.2e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM86221.1 - 4.5e-07 29.7 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM86221.1 - 0.00077 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIM86221.1 - 0.0077 16.3 0.3 0.019 15.0 0.2 1.6 1 0 0 1 1 1 1 PWI domain Methyltransf_31 PF13847.1 EIM86222.1 - 6.4e-14 51.8 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM86222.1 - 2e-12 47.1 0.0 7.1e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86222.1 - 3.5e-12 46.6 0.0 9.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIM86222.1 - 7e-12 45.0 0.1 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIM86222.1 - 9.8e-12 45.4 0.2 2.5e-11 44.1 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM86222.1 - 2.8e-09 36.8 0.0 1.8e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86222.1 - 9.1e-07 29.1 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM86222.1 - 9.9e-07 28.2 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIM86222.1 - 1.4e-06 28.6 0.1 9.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIM86222.1 - 6.2e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EIM86222.1 - 0.00078 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.13 EIM86222.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EIM86222.1 - 0.0014 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIM86222.1 - 0.0014 18.0 0.1 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EIM86222.1 - 0.0017 17.9 0.1 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.11 EIM86222.1 - 0.0017 17.3 0.0 0.0031 16.4 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EIM86222.1 - 0.0038 15.9 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 EIM86222.1 - 0.0038 17.2 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.10 EIM86222.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Sugarporin_N PF11471.3 EIM86222.1 - 0.026 14.1 2.1 0.049 13.2 1.4 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Methyltransf_10 PF05971.7 EIM86222.1 - 0.04 13.0 0.1 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF890) Methyltransf_32 PF13679.1 EIM86222.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 EIM86223.1 - 0.042 13.8 0.1 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain DUF605 PF04652.11 EIM86223.1 - 0.27 10.5 23.9 0.4 10.0 16.6 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EIM86223.1 - 4.7 5.3 11.0 6.5 4.8 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2 PF00096.21 EIM86224.1 - 0.0017 18.5 2.5 0.0041 17.3 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM86224.1 - 0.003 17.7 2.6 0.0084 16.3 1.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger SWI-SNF_Ssr4 PF08549.5 EIM86225.1 - 1.6e-11 43.2 0.3 5e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Ribosomal_L29 PF00831.18 EIM86225.1 - 0.11 12.1 0.3 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein DUF1840 PF08895.6 EIM86225.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Siah-Interact_N PF09032.6 EIM86225.1 - 6 6.9 8.4 0.93 9.5 1.5 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal Proteasome PF00227.21 EIM86227.1 - 7.4e-32 110.1 0.0 1e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.4 EIM86229.1 - 5.5e-56 189.2 1.7 6.6e-56 189.0 1.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Pkinase PF00069.20 EIM86232.1 - 1.3e-40 139.1 0.0 5.5e-28 97.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86232.1 - 6.3e-25 87.7 0.0 2.3e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM86232.1 - 1.5e-06 27.4 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIM86232.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM86232.1 - 0.005 16.2 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EIM86232.1 - 0.01 14.7 0.1 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 AARP2CN PF08142.7 EIM86233.1 - 0.034 13.6 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Methyltransf_23 PF13489.1 EIM86234.1 - 2.9e-15 56.3 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM86234.1 - 7.2e-15 54.8 0.0 4.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86234.1 - 5.5e-13 49.2 0.0 9.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86234.1 - 2.2e-11 44.3 0.0 1.7e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86234.1 - 8.1e-09 35.8 0.0 4.7e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM86234.1 - 1.2e-05 25.3 0.0 3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86234.1 - 1.4e-05 25.3 0.0 7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM86234.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIM86234.1 - 0.00033 19.8 0.0 0.043 12.9 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EIM86234.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CheR PF01739.13 EIM86234.1 - 0.0013 18.0 0.0 0.0085 15.3 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain DUF3321 PF11968.3 EIM86234.1 - 0.0028 17.3 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_4 PF02390.12 EIM86234.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EIM86234.1 - 0.0088 15.4 0.0 0.076 12.4 0.0 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EIM86234.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EIM86234.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EIM86234.1 - 0.042 12.9 0.0 0.086 11.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 EIM86234.1 - 0.087 13.6 0.0 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF3664 PF12406.3 EIM86236.1 - 1.3 9.6 9.4 2 9.0 6.5 1.4 1 1 0 1 1 1 0 Surface protein MFS_1 PF07690.11 EIM86237.1 - 6.8e-29 100.6 43.6 6.1e-27 94.2 22.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EIM86237.1 - 1.1 7.7 15.6 0.0056 15.2 2.7 2.1 1 1 1 2 2 2 0 Reduced folate carrier VSP PF03302.8 EIM86238.1 - 0.0044 15.7 3.2 0.0045 15.6 2.2 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein Neuroparsin PF07327.6 EIM86238.1 - 0.056 13.6 0.3 0.067 13.4 0.2 1.2 1 0 0 1 1 1 0 Neuroparsin COesterase PF00135.23 EIM86239.1 - 9.2e-91 305.1 0.0 2e-90 304.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86239.1 - 9.4e-05 22.0 0.1 0.00034 20.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86239.1 - 0.016 14.4 0.5 0.032 13.4 0.4 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family polyprenyl_synt PF00348.12 EIM86240.1 - 6.3e-45 153.0 0.0 8.4e-22 77.2 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF3599 PF12206.3 EIM86240.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Thyroglobulin_1 PF00086.13 EIM86241.1 - 0.0034 16.7 4.1 0.52 9.7 0.2 3.0 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Glycos_transf_3 PF00591.16 EIM86242.1 - 1.1e-77 260.9 0.0 1.3e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EIM86242.1 - 6.4e-07 28.8 0.0 1.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain HisG PF01634.13 EIM86243.1 - 9.7e-48 161.8 0.0 1.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EIM86243.1 - 1e-26 92.6 0.0 2.4e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EIM86243.1 - 0.0026 17.3 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Dot_icm_IcmQ PF09475.5 EIM86245.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF2975 PF11188.3 EIM86246.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) SKG6 PF08693.5 EIM86246.1 - 0.022 14.0 0.4 0.047 13.0 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM51 PF15345.1 EIM86246.1 - 0.055 13.1 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.11 EIM86246.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CSD PF00313.17 EIM86246.1 - 0.17 11.7 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF1180 PF06679.7 EIM86246.1 - 0.21 11.4 1.5 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Rifin_STEVOR PF02009.11 EIM86246.1 - 0.27 10.8 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family YukD PF08817.5 EIM86247.1 - 0.072 13.6 0.2 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-CCHC_4 PF14392.1 EIM86247.1 - 0.8 9.4 4.3 1.5 8.5 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle PARP PF00644.15 EIM86248.1 - 9.5e-12 44.7 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EIM86248.1 - 1.8e-08 33.8 0.0 6e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short PF00106.20 EIM86249.1 - 2e-29 102.6 0.9 2.6e-29 102.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86249.1 - 4.1e-23 82.4 0.0 4.9e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM86249.1 - 2.2e-09 37.2 0.5 3.4e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM86249.1 - 0.00096 18.6 0.1 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2321 PF10083.4 EIM86250.1 - 0.53 9.7 3.0 1.2 8.6 2.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF668 PF05003.7 EIM86250.1 - 7.3 6.8 7.6 3.3 7.9 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF668) Peptidase_C6 PF00851.13 EIM86250.1 - 8.3 4.9 17.7 10 4.6 12.3 1.1 1 0 0 1 1 1 0 Helper component proteinase Coprogen_oxidas PF01218.13 EIM86251.1 - 1.1e-114 381.9 0.0 1e-113 378.7 0.0 2.0 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase polyprenyl_synt PF00348.12 EIM86252.1 - 1.6e-45 155.0 0.0 2.2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DEAD PF00270.24 EIM86253.1 - 7.3e-12 45.1 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM86253.1 - 0.0062 16.3 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEDD_Tnp_IS110 PF01548.12 EIM86253.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Transposase OTT_1508_deam PF14441.1 EIM86254.1 - 0.044 13.6 0.2 0.17 11.6 0.0 2.2 1 1 0 1 1 1 0 OTT_1508-like deaminase UQ_con PF00179.21 EIM86256.1 - 5.4e-41 139.3 0.0 6.6e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EIM86256.1 - 8.7e-19 66.8 0.5 1.6e-18 66.0 0.3 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EIM86256.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Aminotran_1_2 PF00155.16 EIM86257.1 - 5.7e-13 48.5 0.0 1.8e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3129 PF11327.3 EIM86259.1 - 1.5e-29 103.0 9.7 1.5e-29 103.0 6.7 2.9 2 2 1 3 3 3 1 Protein of unknown function (DUF3129) Merozoite_SPAM PF07133.6 EIM86259.1 - 0.047 13.5 1.7 0.071 12.9 1.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF572 PF04502.8 EIM86259.1 - 9.5 5.3 9.3 0.58 9.3 2.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pro-kuma_activ PF09286.6 EIM86260.1 - 6.4e-49 165.6 0.2 2e-48 164.0 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM86260.1 - 2.8e-06 26.6 1.2 4.9e-06 25.9 0.8 1.3 1 0 0 1 1 1 1 Subtilase family Ribosomal_60s PF00428.14 EIM86261.1 - 0.42 11.0 7.2 4.6 7.7 0.3 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein Oxidored_q3 PF00499.15 EIM86263.1 - 0.015 15.0 1.1 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pro-kuma_activ PF09286.6 EIM86264.1 - 8.4e-39 132.8 0.0 1.9e-38 131.7 0.0 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM86264.1 - 7.2e-06 25.3 3.2 2.5e-05 23.5 2.5 1.6 2 0 0 2 2 2 1 Subtilase family Herpes_gE PF02480.11 EIM86265.1 - 0.3 9.3 5.6 2.9 6.0 0.2 2.5 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E DUF4013 PF13197.1 EIM86265.1 - 3.2 7.0 22.6 3.5 6.9 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Na_K-ATPase PF00287.13 EIM86265.1 - 4.3 6.0 5.3 17 4.0 0.3 2.1 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain 2OG-FeII_Oxy_3 PF13640.1 EIM86266.1 - 2.3e-07 31.2 0.1 5.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM86266.1 - 9.5e-05 22.6 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_16 PF00722.16 EIM86268.1 - 3.5e-10 39.4 0.0 9.9e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acetyltransf_10 PF13673.1 EIM86270.1 - 3.6e-07 30.3 0.0 4.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM86270.1 - 2.6e-06 27.5 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM86270.1 - 4.7e-06 26.5 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EIM86270.1 - 0.055 13.3 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EIM86270.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy PF03171.15 EIM86271.1 - 1.5e-06 28.3 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM86271.1 - 1.2e-05 25.7 0.0 2.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_7C PF02709.9 EIM86271.1 - 0.054 12.9 0.1 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase Glyco_transf_8 PF01501.15 EIM86272.1 - 6.5e-16 58.4 0.0 1.4e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EIM86273.1 - 1.8e-41 142.0 40.6 7.7e-41 139.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIM86274.1 - 1.7e-30 105.9 54.4 1.1e-25 90.1 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM86275.1 - 4.2e-07 30.4 0.1 1.6e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM86275.1 - 0.0015 18.7 0.0 0.0086 16.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.15 EIM86276.1 - 8.1e-57 190.9 3.1 8.9e-57 190.7 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ArfGap PF01412.13 EIM86277.1 - 2.2e-34 117.7 0.3 2.2e-34 117.7 0.2 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf 2OG-FeII_Oxy_3 PF13640.1 EIM86278.1 - 2e-06 28.2 0.2 6e-06 26.6 0.1 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM86278.1 - 0.00033 20.8 0.0 0.00075 19.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIM86278.1 - 0.081 12.5 0.6 0.87 9.2 0.0 2.9 4 1 0 4 4 4 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM86279.1 - 0.00022 21.7 0.2 0.0011 19.3 0.0 2.3 4 0 0 4 4 4 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM86279.1 - 0.0003 21.0 0.0 0.0008 19.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM86280.1 - 0.00035 21.0 0.0 0.00083 19.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM86280.1 - 0.0071 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 EIM86281.1 - 9e-21 74.3 0.2 2.5e-20 72.8 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM86281.1 - 5.3e-10 38.7 3.5 2.2e-07 30.1 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM86281.1 - 4e-09 36.3 0.4 9.3e-09 35.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM86281.1 - 7.9e-08 31.6 0.1 1.1e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM86281.1 - 3.9e-06 26.2 0.2 6.1e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM86281.1 - 2.9e-05 24.0 2.1 6e-05 23.0 1.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM86281.1 - 3.9e-05 22.8 0.7 0.061 12.3 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EIM86281.1 - 0.00011 22.5 0.1 0.0011 19.3 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM86281.1 - 0.00064 19.8 0.2 0.0026 17.8 0.2 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM86281.1 - 0.00075 18.4 3.4 0.00075 18.4 2.4 1.8 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIM86281.1 - 0.0015 17.4 1.2 0.0027 16.6 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIM86281.1 - 0.0022 16.5 1.6 0.0045 15.5 1.1 1.7 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EIM86281.1 - 0.013 15.2 0.9 0.88 9.3 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIM86281.1 - 0.015 14.9 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EIM86281.1 - 0.04 12.5 5.0 2.5 6.6 0.1 2.4 2 1 1 3 3 3 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EIM86281.1 - 0.044 13.5 0.7 0.072 12.8 0.5 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EIM86281.1 - 0.1 11.9 0.2 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EIM86281.1 - 0.22 10.9 1.2 0.65 9.4 0.7 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SIR2 PF02146.12 EIM86282.1 - 6.4e-51 172.5 0.0 8.1e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-MYND PF01753.13 EIM86283.1 - 4.7e-10 39.1 16.1 9.3e-10 38.2 11.2 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 EIM86283.1 - 0.053 11.1 1.6 0.075 10.6 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 EB1 PF03271.12 EIM86285.1 - 1.2e-14 54.0 1.0 2.2e-14 53.1 0.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EIM86285.1 - 2.3e-07 30.8 0.5 3.8e-07 30.1 0.1 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Suppressor_APC PF11414.3 EIM86285.1 - 0.065 13.0 0.8 0.23 11.2 0.3 2.0 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein tRNA-synt_1c PF00749.16 EIM86286.1 - 1.8e-99 332.4 0.0 8e-99 330.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIM86286.1 - 5e-31 107.7 0.0 9e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EIM86286.1 - 0.011 16.2 0.1 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM86286.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM86286.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Chitin_synth_1 PF01644.12 EIM86291.1 - 1.7e-87 291.3 0.1 2.6e-87 290.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIM86291.1 - 1.9e-32 110.7 0.1 4.5e-32 109.5 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIM86291.1 - 8.7e-23 80.4 0.1 7.7e-17 60.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIM86291.1 - 3.1e-06 27.1 0.0 7.2e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIM86291.1 - 0.00013 21.7 6.3 0.00013 21.7 4.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 APH PF01636.18 EIM86292.1 - 3.5e-07 30.2 1.6 2.3e-06 27.5 1.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Innate_immun PF12782.2 EIM86293.1 - 0.12 11.5 1.7 0.17 11.0 1.2 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF1152 PF06626.7 EIM86294.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Ndc1_Nup PF09531.5 EIM86294.1 - 0.7 8.2 7.0 0.94 7.8 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.20 EIM86297.1 - 2.1e-13 50.0 0.0 3.6e-13 49.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86297.1 - 0.0011 18.0 0.0 0.0024 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4131 PF13567.1 EIM86298.1 - 0.014 14.8 0.3 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SKG6 PF08693.5 EIM86298.1 - 0.029 13.7 0.6 0.071 12.4 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EIM86298.1 - 0.029 14.0 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Na_Ca_ex PF01699.19 EIM86298.1 - 0.073 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Methyltransf_2 PF00891.13 EIM86299.1 - 5.3e-31 107.6 0.0 7.7e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM86299.1 - 0.00017 22.1 0.0 0.00042 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM86299.1 - 0.00059 19.5 0.0 0.002 17.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86299.1 - 0.0026 18.1 0.0 0.0069 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIM86300.1 - 2.7e-43 147.8 0.0 4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM86300.1 - 0.00083 19.9 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86300.1 - 0.0064 16.8 0.0 0.074 13.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain RPA_C PF08784.6 EIM86300.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal EthD PF07110.6 EIM86301.1 - 1.3e-16 61.3 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 EthD domain NAD_binding_10 PF13460.1 EIM86302.1 - 2.8e-14 53.5 0.0 3.6e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM86302.1 - 1.1e-08 34.7 0.0 2.7e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM86302.1 - 0.00038 19.7 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EIM86302.1 - 0.00081 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EIM86302.1 - 0.014 14.2 0.0 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 EIM86302.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIM86302.1 - 0.036 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fibrillarin PF01269.12 EIM86302.1 - 0.048 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Dicistro_VP4 PF11492.3 EIM86302.1 - 0.055 13.4 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 NAD_binding_4 PF07993.7 EIM86302.1 - 0.14 11.0 0.0 0.82 8.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein NAD_binding_2 PF03446.10 EIM86302.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EIM86304.1 - 5.1e-19 68.9 0.1 8.3e-19 68.3 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM86304.1 - 0.00025 20.0 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GMC_oxred_N PF00732.14 EIM86305.1 - 3.9e-45 154.2 0.0 4.5e-26 91.7 0.1 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM86305.1 - 2.8e-27 95.7 0.0 5.2e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM86305.1 - 2.9e-05 24.0 0.6 0.00035 20.5 0.3 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM86305.1 - 4.5e-05 22.5 0.1 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM86305.1 - 0.00014 20.8 0.4 0.00021 20.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIM86305.1 - 0.00032 19.7 0.1 0.0005 19.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM86305.1 - 0.00088 17.8 0.1 0.0014 17.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM86305.1 - 0.0065 16.5 0.1 0.52 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM86305.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM86305.1 - 0.026 13.5 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EIM86305.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIM86305.1 - 0.12 12.1 0.2 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIM86305.1 - 0.18 12.2 0.0 0.62 10.5 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM86305.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_10 PF13460.1 EIM86306.1 - 3.4e-21 76.0 0.1 6e-21 75.2 0.1 1.4 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIM86306.1 - 1e-10 41.4 0.0 5.2e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM86306.1 - 1.1e-07 31.3 0.0 5.9e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EIM86306.1 - 1.6e-06 27.3 0.1 2.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIM86306.1 - 6.6e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EIM86306.1 - 0.0001 21.3 0.0 0.0028 16.6 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EIM86306.1 - 0.001 17.8 0.0 0.0058 15.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fibrillarin PF01269.12 EIM86306.1 - 0.003 16.5 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin RmlD_sub_bind PF04321.12 EIM86306.1 - 0.0032 16.4 0.0 0.29 10.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.15 EIM86306.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EIM86306.1 - 0.037 14.3 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EIM86307.1 - 1.2e-22 81.0 0.0 7.4e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM86307.1 - 4.1e-15 54.9 0.0 1.5e-13 49.8 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIM86307.1 - 9.6e-11 41.9 0.0 0.00024 21.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM86307.1 - 8.6e-10 38.0 0.0 1.6e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIM86307.1 - 1.5e-08 34.5 0.4 1.9e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM86307.1 - 2.6e-07 29.9 3.9 0.094 11.6 0.2 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIM86307.1 - 7.3e-06 26.1 0.5 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIM86307.1 - 1e-05 25.3 2.4 0.079 12.7 0.0 3.6 3 1 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIM86307.1 - 1.6e-05 25.2 3.3 0.0013 19.1 0.4 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIM86307.1 - 2.7e-05 24.3 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EIM86307.1 - 0.00037 19.6 0.9 0.44 9.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EIM86307.1 - 0.001 18.0 5.2 0.2 10.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 EIM86307.1 - 0.0034 16.5 0.0 0.29 10.1 0.0 2.4 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EIM86307.1 - 0.0036 16.2 3.4 0.15 10.9 0.5 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A ThiF PF00899.16 EIM86307.1 - 0.0046 16.7 2.3 0.036 13.8 0.1 2.3 2 0 0 2 2 2 1 ThiF family FAD_binding_3 PF01494.14 EIM86307.1 - 0.0097 14.9 3.4 0.14 11.2 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EIM86307.1 - 0.01 14.3 5.7 0.58 8.5 0.1 3.4 4 0 0 4 4 4 0 HI0933-like protein Lycopene_cycl PF05834.7 EIM86307.1 - 0.048 12.5 0.2 21 3.9 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM86307.1 - 0.064 11.8 2.5 1.4 7.5 0.3 2.4 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.12 EIM86307.1 - 0.098 13.0 1.7 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EIM86307.1 - 0.13 11.8 0.1 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 KR domain ApbA PF02558.11 EIM86307.1 - 0.13 11.6 2.2 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EIM86307.1 - 0.16 11.9 2.4 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 EIM86307.1 - 0.22 11.5 0.4 20 5.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EIM86307.1 - 0.23 11.1 1.4 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EIM86307.1 - 0.27 10.8 2.9 1.9 8.0 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EIM86307.1 - 0.36 9.8 3.4 3.5 6.5 1.3 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Glyco_transf_8 PF01501.15 EIM86308.1 - 2.3e-21 76.2 0.0 3.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EIM86308.1 - 0.0066 16.2 0.1 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase NAD_binding_10 PF13460.1 EIM86309.1 - 4.7e-17 62.5 0.0 6.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM86309.1 - 7.5e-08 32.0 0.0 1.1e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM86309.1 - 7.6e-07 28.6 0.0 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EIM86309.1 - 4.4e-05 22.6 0.0 5.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIM86309.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Fibrillarin PF01269.12 EIM86309.1 - 0.009 14.9 0.0 0.029 13.3 0.0 1.7 2 0 0 2 2 2 1 Fibrillarin Semialdhyde_dh PF01118.19 EIM86309.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIM86309.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EIM86309.1 - 0.14 11.0 0.0 6.5 5.5 0.0 2.8 1 1 1 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 EIM86309.1 - 0.14 10.7 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GMC_oxred_C PF05199.8 EIM86310.1 - 9.4e-20 71.3 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GST_N PF02798.15 EIM86312.1 - 5.7e-15 55.2 0.0 9.7e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIM86312.1 - 1.4e-14 54.0 0.0 2.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM86312.1 - 7.8e-14 51.4 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM86312.1 - 4.1e-11 42.7 0.0 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM86312.1 - 1.7e-07 30.9 0.1 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM86312.1 - 0.0056 17.1 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 EIM86313.1 - 1.2e-27 96.7 0.0 1.5e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM86313.1 - 5.6e-11 42.7 0.1 8.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM86313.1 - 3.8e-05 23.2 0.1 0.00043 19.7 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM86313.1 - 0.00015 20.5 0.1 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM86313.1 - 0.002 17.8 0.1 0.0035 17.0 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EIM86313.1 - 0.0046 17.3 1.7 0.0088 16.4 0.1 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIM86313.1 - 0.02 14.7 0.2 0.063 13.2 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 EIM86313.1 - 0.054 14.0 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Phage_Coat_A PF05357.8 EIM86315.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage Coat Protein A WHG PF13305.1 EIM86315.1 - 0.084 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 WHG domain adh_short PF00106.20 EIM86317.1 - 1.8e-19 70.2 0.2 1.6e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM86317.1 - 2e-07 30.8 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM86317.1 - 1.1e-05 25.3 0.0 0.00044 20.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM86317.1 - 5e-05 22.8 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM86317.1 - 0.0054 16.7 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIM86318.1 - 9.5e-16 57.9 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM86318.1 - 3.6e-15 56.4 0.0 4.7e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM86318.1 - 1.7e-06 27.5 0.0 8.7e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 EIM86318.1 - 0.0013 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EIM86318.1 - 0.0021 17.1 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EIM86318.1 - 0.0058 15.5 0.1 0.72 8.7 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EIM86318.1 - 0.0074 15.2 0.0 1.4 7.7 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIM86318.1 - 0.0095 14.6 0.0 0.034 12.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 EIM86318.1 - 0.13 11.6 0.6 0.36 10.1 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2615 PF11027.3 EIM86321.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) GRP PF07172.6 EIM86322.1 - 0.23 11.9 22.8 8.1e+02 0.5 15.8 2.4 1 1 0 1 1 1 0 Glycine rich protein family Gag_spuma PF03276.9 EIM86322.1 - 5.3 5.2 8.8 6.1 5.0 6.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Toxin_57 PF15535.1 EIM86322.1 - 8.2 6.5 13.3 1.6 8.8 0.5 3.8 1 1 3 4 4 4 0 Putative toxin 57 Orthopox_C10L PF07020.6 EIM86322.1 - 9 6.9 12.6 14 6.3 6.4 2.2 1 1 1 2 2 2 0 Orthopoxvirus C10L protein p450 PF00067.17 EIM86324.1 - 8.3e-67 225.6 0.0 1e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM86325.1 - 5.5e-66 222.9 0.0 6.9e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEMT PF04191.8 EIM86326.1 - 4e-12 46.1 1.2 9.2e-12 45.0 0.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIM86326.1 - 7.1e-11 42.1 0.2 1.3e-10 41.3 0.0 1.5 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIM86326.1 - 0.00069 18.2 0.3 0.00089 17.9 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM86326.1 - 0.04 13.1 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.9 EIM86327.1 - 6.5e-11 42.2 0.2 6.5e-11 42.2 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM86327.1 - 5.1e-08 32.9 0.9 2.4e-07 30.8 0.3 2.2 1 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM86327.1 - 0.014 14.0 0.1 0.02 13.4 0.1 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1989 PF09347.5 EIM86327.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) O-FucT PF10250.4 EIM86328.1 - 1.3e-08 34.4 0.1 9.8e-07 28.1 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase p450 PF00067.17 EIM86329.1 - 7.6e-67 225.8 0.0 9.6e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotH PF08757.6 EIM86329.1 - 0.022 14.0 0.1 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 CotH protein Aldo_ket_red PF00248.16 EIM86330.1 - 3.2e-64 216.4 0.0 3.6e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EF-hand_1 PF00036.27 EIM86331.1 - 0.0075 15.5 0.0 0.022 14.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EIM86331.1 - 0.015 14.5 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EIM86331.1 - 0.041 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Glyco_hydro_61 PF03443.9 EIM86332.1 - 5.7e-45 153.8 0.1 7.1e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4157 PF13699.1 EIM86333.1 - 1.2 9.3 7.6 0.31 11.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Asp PF00026.18 EIM86334.1 - 1.5e-34 119.7 0.1 1.2e-33 116.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM86334.1 - 1.8e-05 24.7 1.6 7.4e-05 22.7 1.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BCMA-Tall_bind PF09257.5 EIM86340.1 - 0.18 11.7 3.3 0.33 10.9 2.3 1.4 1 0 0 1 1 1 0 BCMA, TALL-1 binding DIOX_N PF14226.1 EIM86341.1 - 1.3e-28 99.8 0.0 2.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM86341.1 - 5e-21 74.8 0.0 9.1e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPC25 PF06703.6 EIM86342.1 - 0.39 10.2 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) F-box-like PF12937.2 EIM86344.1 - 0.00015 21.4 0.7 0.00086 18.9 0.5 2.4 1 1 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EIM86344.1 - 0.012 15.9 0.3 0.1 13.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CDC24 PF06395.6 EIM86346.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RTA1 PF04479.8 EIM86347.1 - 4.7e-48 163.6 0.2 6.6e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3180 PF11377.3 EIM86347.1 - 0.23 11.3 6.9 0.31 10.8 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Glyco_hydro_61 PF03443.9 EIM86349.1 - 6.7e-63 212.4 0.4 8.8e-63 212.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EIM86349.1 - 1.6e-11 43.6 12.0 1.6e-11 43.6 8.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DNA_ligase_OB_2 PF14743.1 EIM86354.1 - 2.8e-27 94.1 0.4 6.6e-27 92.9 0.3 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 EIM86354.1 - 7.3e-18 64.6 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Virulence_RhuM PF13310.1 EIM86355.1 - 0.14 11.1 0.1 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family DEAD PF00270.24 EIM86357.1 - 1.5e-10 40.7 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM86357.1 - 3.2e-10 39.7 0.0 1.5e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM86357.1 - 0.0059 15.4 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIM86357.1 - 0.0083 15.9 0.1 0.094 12.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 EIM86357.1 - 0.0097 14.5 0.1 0.17 10.4 0.0 2.0 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer GATA PF00320.22 EIM86361.1 - 0.002 17.4 3.1 0.0072 15.6 1.1 2.3 2 0 0 2 2 2 1 GATA zinc finger GST_N PF02798.15 EIM86362.1 - 6.3e-17 61.5 0.0 1.6e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIM86362.1 - 1.4e-16 60.4 0.0 2.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM86362.1 - 2.7e-15 56.1 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM86362.1 - 4.7e-12 45.7 0.0 7.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM86362.1 - 4.8e-08 32.7 0.2 1.1e-07 31.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM86362.1 - 0.0096 16.3 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3290 PF11694.3 EIM86364.1 - 0.045 13.4 1.5 0.48 10.1 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) DUF3329 PF11808.3 EIM86364.1 - 0.075 13.1 5.1 0.42 10.7 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3329) Cytochrom_B561 PF03188.11 EIM86364.1 - 0.52 10.1 7.3 0.26 11.1 1.3 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF2422 PF10337.4 EIM86364.1 - 1.5 7.5 5.5 0.53 9.0 2.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) YhhN PF07947.9 EIM86364.1 - 1.8 7.9 9.1 0.44 9.9 0.3 2.1 2 0 0 2 2 2 0 YhhN-like protein adh_short PF00106.20 EIM86366.1 - 2.4e-23 82.8 0.0 7.5e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86366.1 - 3.3e-19 69.5 0.0 6.1e-19 68.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM86366.1 - 3.4e-07 30.0 0.0 1.1e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 KR domain Phosducin PF02114.11 EIM86367.1 - 2.9e-15 55.7 0.0 4.7e-08 32.0 0.0 3.0 2 1 0 2 2 2 2 Phosducin AIG2_2 PF13772.1 EIM86368.1 - 2.8e-05 24.1 0.1 7.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 AIG2-like family Trm56 PF01994.11 EIM86369.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Enamelin PF15362.1 EIM86373.1 - 0.029 12.4 3.6 1.1 7.2 0.1 2.3 1 1 1 2 2 2 0 Enamelin FAD_binding_3 PF01494.14 EIM86375.1 - 1.5e-16 60.4 0.4 1.4e-08 34.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM86375.1 - 8.1e-10 38.1 5.0 1.8e-05 23.8 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM86375.1 - 1.3e-06 27.5 0.2 2.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM86375.1 - 7.3e-06 24.7 0.4 0.00015 20.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EIM86375.1 - 1.1e-05 25.3 0.1 6.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM86375.1 - 7.1e-05 22.7 0.8 0.00017 21.5 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM86375.1 - 7.3e-05 22.0 0.2 0.0001 21.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM86375.1 - 0.0014 18.9 0.3 0.12 12.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM86375.1 - 0.0021 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIM86375.1 - 0.0091 15.1 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EIM86375.1 - 0.01 14.7 0.1 0.019 13.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM86375.1 - 0.063 11.8 0.3 0.93 8.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EIM86375.1 - 0.22 10.8 0.3 0.34 10.2 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4382 PF14321.1 EIM86376.1 - 0.06 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) Thiolase_N PF00108.18 EIM86377.1 - 4.5e-83 278.2 5.4 4.6e-83 278.2 1.9 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIM86377.1 - 1.5e-45 153.5 0.8 1.5e-45 153.5 0.5 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIM86377.1 - 0.018 14.5 1.5 0.018 14.5 1.0 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIM86377.1 - 0.023 14.3 1.1 4.6 6.9 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_7 PF02796.10 EIM86377.1 - 0.065 13.1 0.9 8.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Oxidored_q2 PF00420.19 EIM86378.1 - 1.4e-06 27.7 2.5 1.5e-05 24.4 0.8 2.2 1 1 1 2 2 2 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MraZ PF02381.13 EIM86379.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 MraZ protein CTF_NFI PF00859.13 EIM86380.1 - 9.7 5.8 8.6 11 5.7 5.9 1.0 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region DUF575 PF04746.7 EIM86383.1 - 0.026 14.5 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) DUF3290 PF11694.3 EIM86383.1 - 0.15 11.7 0.9 0.31 10.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Arif-1 PF06770.6 EIM86383.1 - 0.21 10.9 5.3 0.19 11.0 0.4 2.5 2 1 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Ank_2 PF12796.2 EIM86385.1 - 3.7e-29 100.9 2.6 4.5e-16 58.9 0.1 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM86385.1 - 5.7e-25 85.8 11.3 1.5e-05 24.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EIM86385.1 - 1.1e-22 79.9 1.3 1.7e-07 31.5 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM86385.1 - 2.5e-16 58.1 1.2 0.0099 16.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EIM86385.1 - 1.3e-10 41.1 6.0 0.00012 22.2 0.2 3.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 EIM86385.1 - 8.3e-05 22.5 6.0 0.09 12.8 0.4 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1843) DUF4369 PF14289.1 EIM86385.1 - 0.03 14.3 0.1 49 4.0 0.0 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4369) UBA PF00627.26 EIM86385.1 - 0.073 12.9 0.1 25 4.8 0.0 4.0 5 0 0 5 5 5 0 UBA/TS-N domain DUF1771 PF08590.5 EIM86385.1 - 0.086 12.8 5.3 18 5.4 0.1 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1771) NACHT PF05729.7 EIM86386.1 - 4.7e-15 55.6 0.0 1.3e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM86386.1 - 0.00011 22.2 0.1 0.00044 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EIM86386.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 EIM86386.1 - 0.047 13.8 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM86386.1 - 0.058 13.5 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MbeD_MobD PF04899.7 EIM86389.1 - 0.54 10.1 4.8 8.1 6.4 0.0 3.3 3 0 0 3 3 3 0 MbeD/MobD like DivIC PF04977.10 EIM86389.1 - 3.4 7.2 10.9 6.7 6.2 0.0 4.6 5 0 0 5 5 5 0 Septum formation initiator FlxA PF14282.1 EIM86389.1 - 3.8 7.4 13.2 38 4.2 1.6 4.9 4 1 0 4 4 4 0 FlxA-like protein Glypican PF01153.14 EIM86389.1 - 3.9 5.9 6.0 13 4.1 0.0 2.6 2 0 0 2 2 2 0 Glypican Prefoldin PF02996.12 EIM86389.1 - 5.3 6.7 9.3 40 3.8 0.2 4.7 5 1 0 5 5 5 0 Prefoldin subunit Fib_alpha PF08702.5 EIM86389.1 - 7.6 6.6 10.3 2.9 8.0 0.4 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 EIM86389.1 - 8.7 6.1 9.6 1.7 8.4 0.1 3.5 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Fungal_trans PF04082.13 EIM86391.1 - 4.3e-23 81.5 0.0 1.2e-22 80.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86391.1 - 0.0084 16.0 16.2 0.019 14.8 0.6 3.4 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxoacid_dh PF00198.18 EIM86391.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) FliD_N PF02465.13 EIM86391.1 - 0.13 12.6 0.3 0.29 11.5 0.2 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus zf-RING-like PF08746.6 EIM86391.1 - 7.4 6.6 9.3 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 RING-like domain Fungal_trans PF04082.13 EIM86392.1 - 5.3e-22 77.9 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86392.1 - 0.00023 21.0 5.3 0.00023 21.0 3.7 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EIM86393.1 - 8.1e-10 38.2 0.4 3.4e-08 33.0 0.2 2.7 2 0 0 2 2 2 2 F-box-like He_PIG PF05345.7 EIM86395.1 - 5.7e-11 42.2 23.7 1e-07 31.8 4.8 5.0 4 0 0 4 4 4 4 Putative Ig domain Big_3_4 PF13754.1 EIM86395.1 - 0.032 14.5 1.0 0.032 14.5 0.7 2.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) HEAT_EZ PF13513.1 EIM86396.1 - 8.7e-24 83.3 13.5 0.00018 21.9 0.0 11.3 11 1 0 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 EIM86396.1 - 3e-19 69.0 8.8 0.00062 19.9 0.0 8.3 3 2 7 10 10 10 8 HEAT repeats HEAT PF02985.17 EIM86396.1 - 8.5e-14 50.3 15.7 0.0026 17.6 0.0 8.8 10 0 0 10 10 8 3 HEAT repeat IBN_N PF03810.14 EIM86396.1 - 1.7e-07 31.0 0.8 1.2e-06 28.3 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.7 EIM86396.1 - 1.4e-06 28.1 0.0 0.032 13.8 0.0 4.6 5 1 0 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EIM86396.1 - 2.1e-05 23.0 0.0 4 5.6 0.0 4.5 4 1 0 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 EIM86396.1 - 0.00045 19.6 0.0 2.6 7.3 0.0 5.3 5 1 1 6 6 6 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIM86396.1 - 0.00046 20.5 0.0 3.2 8.1 0.0 3.9 4 0 0 4 4 3 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EIM86396.1 - 0.019 14.9 0.0 11 6.0 0.0 4.9 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 EIM86396.1 - 0.084 12.7 0.0 6.3 6.6 0.0 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIM86396.1 - 2 8.3 17.6 11 6.0 0.0 7.6 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat Dynein_light PF01221.13 EIM86398.1 - 2.3e-37 126.8 1.0 2.5e-37 126.7 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EIM86398.1 - 0.056 13.7 0.1 0.063 13.6 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain DEAD PF00270.24 EIM86400.1 - 8.2e-17 61.2 0.0 1.6e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM86400.1 - 5.5e-15 54.9 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM86400.1 - 3.3e-05 23.7 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIM86400.1 - 0.056 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain UvrD-helicase PF00580.16 EIM86400.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Zn_clus PF00172.13 EIM86402.1 - 2.4e-06 27.3 12.7 5.5e-06 26.1 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.8 EIM86403.1 - 4.9e-12 45.4 5.0 6.5e-12 45.0 3.5 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DZR PF12773.2 EIM86403.1 - 0.085 12.6 1.4 0.14 12.0 1.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon TerY-C PF15616.1 EIM86403.1 - 0.12 12.3 1.0 0.15 11.9 0.5 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain TF_Zn_Ribbon PF08271.7 EIM86403.1 - 0.99 8.7 4.9 9.6 5.6 0.7 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding F-box-like PF12937.2 EIM86404.1 - 0.012 15.3 1.9 0.022 14.4 0.2 2.4 2 0 0 2 2 2 0 F-box-like Aldo_ket_red PF00248.16 EIM86405.1 - 7.8e-46 156.1 0.0 9e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 3Beta_HSD PF01073.14 EIM86405.1 - 0.038 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Macro PF01661.16 EIM86405.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Macro domain Ribosomal_L23 PF00276.15 EIM86406.1 - 6.8e-11 41.9 0.1 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 SinI PF08671.5 EIM86406.1 - 0.075 12.4 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Anti-repressor SinI Glyco_hydro_16 PF00722.16 EIM86408.1 - 6.3e-34 116.8 0.6 9.7e-34 116.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AIP3 PF03915.8 EIM86409.1 - 7.8e-107 357.8 5.3 1.5e-106 356.8 3.7 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 EIM86409.1 - 0.022 14.8 5.7 0.2 11.6 0.0 3.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.7 EIM86409.1 - 0.025 14.3 5.5 0.086 12.6 3.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EIM86409.1 - 0.045 14.0 0.6 0.045 14.0 0.4 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.9 EIM86409.1 - 0.069 12.5 5.1 0.49 9.8 3.5 2.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Glyco_hydro_77 PF02446.12 EIM86409.1 - 0.19 10.2 1.8 0.3 9.6 1.3 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase FlaC_arch PF05377.6 EIM86409.1 - 0.33 10.8 7.9 17 5.3 0.2 4.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3810 PF12725.2 EIM86409.1 - 0.51 9.1 0.9 0.91 8.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Baculo_p24 PF05073.7 EIM86409.1 - 0.76 9.3 4.3 3.4 7.1 3.0 2.2 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Muted PF14942.1 EIM86409.1 - 1.1 9.1 9.4 0.32 10.8 2.8 2.9 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein COG2 PF06148.6 EIM86409.1 - 2 8.3 8.8 5 7.0 2.7 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EIM86409.1 - 2.5 7.6 12.4 1.6 8.2 3.6 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) F-box-like PF12937.2 EIM86410.1 - 1.2e-05 24.9 0.9 1.7e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.13 EIM86411.1 - 2.2e-12 46.6 15.9 5.9e-12 45.2 11.0 1.8 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 EIM86412.1 - 5.2e-11 42.0 0.8 1e-10 41.0 0.2 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EIM86412.1 - 0.00081 19.1 1.7 0.01 15.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86412.1 - 0.0037 16.7 0.3 0.0082 15.7 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86413.1 - 6.7e-15 54.4 0.8 1.6e-14 53.3 0.5 1.6 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EIM86413.1 - 1.4e-08 34.3 0.0 3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EIM86413.1 - 1e-07 31.2 0.6 0.00018 21.1 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86413.1 - 3.8e-05 23.0 1.4 0.0017 17.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86413.1 - 5.4e-05 23.7 3.0 0.00021 21.8 0.8 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86413.1 - 0.0034 17.7 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM86413.1 - 0.0046 17.4 0.0 0.026 15.1 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86413.1 - 0.014 15.1 0.2 0.13 12.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM86413.1 - 0.029 14.5 0.4 0.085 13.0 0.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIM86413.1 - 0.048 13.5 0.7 0.73 9.8 0.4 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM86413.1 - 0.066 13.4 0.3 0.37 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CusF_Ec PF11604.3 EIM86415.1 - 3.7 7.4 5.0 1.3 8.9 1.2 1.9 1 1 1 2 2 2 0 Copper binding periplasmic protein CusF DUF4470 PF14737.1 EIM86416.1 - 2.5e-10 40.0 0.0 5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EIM86416.1 - 6.8e-10 38.4 0.2 1.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIM86416.1 - 0.00094 18.9 1.6 0.0091 15.8 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86416.1 - 0.0019 18.7 0.6 0.0069 17.0 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM86416.1 - 0.11 13.1 0.0 0.55 11.0 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86416.1 - 0.13 11.9 0.3 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SLAC1 PF03595.12 EIM86417.1 - 3.2e-47 160.7 47.3 3.7e-47 160.5 32.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EIM86418.1 - 4.1e-51 173.6 38.8 4.6e-51 173.4 26.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel STE2 PF02116.10 EIM86419.1 - 0.0014 17.7 1.7 0.0014 17.7 1.2 2.4 1 1 1 2 2 2 1 Fungal pheromone mating factor STE2 GPCR STE2 PF02116.10 EIM86420.1 - 0.087 11.8 16.4 2.3 7.2 10.5 2.5 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DHBP_synthase PF00926.14 EIM86421.1 - 1.3e-77 259.3 0.1 1.8e-77 259.0 0.1 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.22 EIM86422.1 - 5.5e-34 115.7 9.5 1.5e-20 72.6 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein STE2 PF02116.10 EIM86423.1 - 0.0088 15.1 0.8 0.0088 15.1 0.5 1.9 2 0 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR DUF2721 PF11026.3 EIM86423.1 - 7.3 6.2 8.6 1.9 8.1 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) zf-MYND PF01753.13 EIM86424.1 - 1.2e-06 28.3 13.8 1.2e-06 28.3 9.6 2.1 2 0 0 2 2 2 1 MYND finger p450 PF00067.17 EIM86425.1 - 2e-30 105.7 0.0 2.7e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2911 PF11138.3 EIM86425.1 - 0.053 13.1 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) zf-C2H2 PF00096.21 EIM86426.1 - 6e-08 32.5 7.2 0.0005 20.2 0.0 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM86426.1 - 2.1e-07 30.8 16.8 0.00029 20.9 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM86426.1 - 8.2e-05 22.6 9.5 0.019 15.2 3.8 2.4 3 0 0 3 3 3 2 C2H2-type zinc finger IBR PF01485.16 EIM86426.1 - 0.093 12.6 3.9 0.15 11.9 2.7 1.3 1 0 0 1 1 1 0 IBR domain Zn-ribbon_8 PF09723.5 EIM86426.1 - 0.18 11.7 5.6 6 6.9 3.8 2.2 1 1 0 1 1 1 0 Zinc ribbon domain Orthopox_F8 PF05886.6 EIM86426.1 - 0.23 11.3 2.5 0.18 11.6 0.4 1.8 2 0 0 2 2 2 0 Orthopoxvirus F8 protein zf-C2H2_6 PF13912.1 EIM86426.1 - 1.9 8.5 8.5 12 5.9 0.0 3.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-AN1 PF01428.11 EIM86426.1 - 2.9 7.8 10.4 23 4.9 4.0 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger DUF1768 PF08719.6 EIM86429.1 - 6.4e-26 90.9 0.0 7.2e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) GMC_oxred_N PF00732.14 EIM86430.1 - 2.4e-59 200.9 0.0 3.5e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM86430.1 - 1.3e-36 126.0 0.0 2.7e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DHBP_synthase PF00926.14 EIM86430.1 - 5.7e-34 117.0 0.3 8.1e-29 100.2 0.0 3.2 3 0 0 3 3 3 3 3,4-dihydroxy-2-butanone 4-phosphate synthase DAO PF01266.19 EIM86430.1 - 0.00083 18.3 0.7 0.0015 17.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM86430.1 - 0.0015 18.4 0.0 0.005 16.7 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM86430.1 - 0.0024 16.7 0.9 0.015 14.1 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EIM86430.1 - 0.012 15.6 1.3 0.026 14.5 0.5 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM86430.1 - 0.048 12.5 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EIM86430.1 - 0.082 11.9 0.4 0.39 9.7 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pkinase PF00069.20 EIM86431.1 - 1.1e-14 54.2 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HAD_2 PF13419.1 EIM86431.1 - 4.9e-06 26.8 0.0 1.4e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.12 EIM86431.1 - 0.00084 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ThiG PF05690.9 EIM86431.1 - 0.037 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG BTB PF00651.26 EIM86434.1 - 1.3e-06 28.3 0.0 6.4e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain PRTP PF01366.13 EIM86434.1 - 0.12 10.3 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Rhomboid PF01694.17 EIM86435.1 - 8.6e-09 35.5 14.4 1.5e-08 34.8 7.9 2.7 2 1 0 2 2 2 1 Rhomboid family DUF457 PF04307.9 EIM86435.1 - 0.0061 15.9 1.3 0.018 14.3 0.9 1.8 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) BTB PF00651.26 EIM86436.1 - 5.8e-08 32.7 0.1 5e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 BTB/POZ domain CHAT PF12770.2 EIM86437.1 - 8.3e-06 25.1 0.1 9.1e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 CHAT domain TAF8_C PF10406.4 EIM86438.1 - 0.0083 16.1 0.5 0.043 13.8 0.0 2.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term TPR_12 PF13424.1 EIM86440.1 - 6.6e-12 45.1 23.1 0.26 11.2 0.1 11.4 7 5 6 13 13 13 3 Tetratricopeptide repeat CHAT PF12770.2 EIM86440.1 - 4.4e-09 35.8 0.0 9.1e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_14 PF13428.1 EIM86440.1 - 0.00015 22.0 21.2 4.3 8.2 0.1 10.6 12 1 1 13 13 13 1 Tetratricopeptide repeat SNAP PF14938.1 EIM86440.1 - 0.0024 17.0 1.5 0.18 10.9 0.6 3.1 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 EIM86440.1 - 0.0051 16.6 20.1 2.9 8.0 0.2 9.6 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF3717 PF12512.3 EIM86440.1 - 0.0059 16.2 0.0 1.2 8.7 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3717) TPR_4 PF07721.9 EIM86440.1 - 0.051 14.0 2.9 9.1 7.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1514 PF07438.6 EIM86440.1 - 0.052 13.4 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) TPR_16 PF13432.1 EIM86440.1 - 0.76 10.5 23.1 1.2 9.8 0.2 7.7 8 2 1 9 9 9 0 Tetratricopeptide repeat RNase_H PF00075.19 EIM86442.1 - 3.6e-08 33.8 0.0 6.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNase H GspH PF12019.3 EIM86442.1 - 0.42 10.7 2.4 1.5 8.9 1.0 2.1 1 1 1 2 2 2 0 Type II transport protein GspH RNase_H PF00075.19 EIM86443.1 - 4.8e-07 30.1 0.0 9.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM86443.1 - 2.9e-05 24.2 0.0 6.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Asp PF00026.18 EIM86445.1 - 2.9e-67 227.1 8.2 3.5e-67 226.8 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM86445.1 - 7.6e-06 25.9 2.9 7.6e-06 25.9 2.0 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM86445.1 - 0.037 13.5 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Histone PF00125.19 EIM86446.1 - 3.9e-30 103.7 0.8 6.9e-30 102.9 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM86446.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIM86446.1 - 0.00066 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIM86446.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2360 PF10152.4 EIM86446.1 - 0.087 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CENP-T PF15511.1 EIM86446.1 - 0.1 11.8 1.4 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EIM86447.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM86447.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIM86447.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIM86447.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIM86447.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIM86447.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RhoGAP PF00620.22 EIM86448.1 - 2.3e-46 157.1 0.0 5.3e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIM86448.1 - 1.7e-13 50.5 0.2 2.4e-11 43.6 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adipokin_hormo PF06377.6 EIM86448.1 - 0.049 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Adipokinetic hormone DUF2347 PF09804.4 EIM86448.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PA26 PF04636.8 EIM86448.1 - 1.2 7.7 7.4 0.27 9.9 0.7 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 EIM86448.1 - 2.2 7.8 5.5 7.2 6.1 1.0 2.3 2 0 0 2 2 2 0 IncA protein TMPIT PF07851.8 EIM86448.1 - 3.7 6.5 6.3 0.4 9.7 1.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein F-box-like PF12937.2 EIM86449.1 - 9.4e-08 31.6 2.2 2.9e-05 23.7 0.4 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EIM86449.1 - 0.0007 19.1 0.6 0.0007 19.1 0.4 2.9 3 0 0 3 3 3 1 F-box domain Nucleopor_Nup85 PF07575.8 EIM86450.1 - 1.6e-56 191.6 0.0 2.4e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin BRK PF07533.11 EIM86450.1 - 0.12 11.8 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 BRK domain Acetyltransf_10 PF13673.1 EIM86452.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM86452.1 - 3.4e-06 27.1 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM86452.1 - 8.8e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM86452.1 - 0.0084 15.9 0.0 0.077 12.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM86452.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF1279 PF06916.8 EIM86452.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) SIR2 PF02146.12 EIM86453.1 - 4.6e-60 202.3 0.0 8.9e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EIM86453.1 - 1.1e-07 31.5 0.4 2.1e-05 24.1 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EIM86453.1 - 0.003 17.2 0.4 0.93 9.2 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Pkinase_Tyr PF07714.12 EIM86454.1 - 3.1e-31 108.3 0.0 1.2e-30 106.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM86454.1 - 1.5e-30 106.2 0.0 2.5e-30 105.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIM86454.1 - 0.00069 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM86454.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIM86454.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EIM86454.1 - 0.036 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S9 PF00326.16 EIM86455.1 - 3.3e-35 121.2 0.0 5e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM86455.1 - 3.1e-08 33.4 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM86455.1 - 1.3e-06 28.4 0.0 4.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIM86455.1 - 3.2e-06 26.5 0.0 1.5e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EIM86455.1 - 4.4e-06 26.4 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EIM86455.1 - 1.7e-05 24.3 0.1 0.012 15.0 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EIM86455.1 - 0.00017 20.1 0.3 0.018 13.5 0.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIM86455.1 - 0.015 14.7 0.0 0.24 10.8 0.0 2.4 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EIM86455.1 - 0.034 12.4 0.0 0.057 11.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 EIM86455.1 - 0.071 12.6 0.3 1.9 7.9 0.2 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.23 EIM86455.1 - 0.12 11.0 0.1 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Corona_S2 PF01601.11 EIM86456.1 - 0.06 11.4 0.1 0.067 11.2 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein adh_short_C2 PF13561.1 EIM86458.1 - 1.5e-31 109.9 0.3 1.7e-31 109.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM86458.1 - 4.2e-28 98.3 0.2 6.3e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM86458.1 - 3.4e-08 33.3 0.1 5.8e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Lyase_1 PF00206.15 EIM86458.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lyase p450 PF00067.17 EIM86459.1 - 4.9e-62 209.9 0.0 6.4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Smr PF01713.16 EIM86460.1 - 7.5e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EIM86460.1 - 0.014 15.3 1.3 0.023 14.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) CHAT PF12770.2 EIM86461.1 - 1.2e-36 126.3 0.0 2.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM86461.1 - 1.5e-11 44.0 14.5 0.0028 17.5 0.1 9.3 5 2 6 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86461.1 - 4.7e-11 42.1 7.7 0.0043 16.6 0.0 7.7 5 3 4 9 9 9 2 TPR repeat TPR_2 PF07719.12 EIM86461.1 - 1.7e-06 27.5 3.7 3.3 7.8 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86461.1 - 6.8e-06 25.4 1.2 9.1 6.0 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM86461.1 - 0.011 15.4 0.6 9.4 6.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86461.1 - 0.038 14.6 11.1 8.3 7.2 0.5 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat RRF PF01765.14 EIM86461.1 - 0.14 11.6 0.0 0.4 10.1 0.0 1.7 1 0 0 1 1 1 0 Ribosome recycling factor TPR_10 PF13374.1 EIM86461.1 - 0.89 9.5 12.4 45 4.1 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86461.1 - 1.6 8.7 7.3 11 6.1 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4164 PF13747.1 EIM86461.1 - 2.2 8.4 7.2 5 7.3 0.1 5.0 8 0 0 8 8 7 0 Domain of unknown function (DUF4164) RNase_H PF00075.19 EIM86462.1 - 6e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM86462.1 - 2.5e-05 24.5 0.0 6.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GPI-anchored PF10342.4 EIM86464.1 - 1.7e-07 31.5 1.9 6.2e-07 29.8 1.3 2.0 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PA_decarbox PF05870.6 EIM86466.1 - 5.6e-09 35.6 0.2 6.9e-09 35.3 0.1 1.3 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DUF2015 PF09435.5 EIM86468.1 - 6.3e-33 113.2 0.0 6.9e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) SOCS_box PF07525.11 EIM86468.1 - 0.025 14.4 1.8 0.057 13.2 1.2 1.6 1 0 0 1 1 1 0 SOCS box DUF98 PF01947.11 EIM86469.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF98) FAP PF07174.6 EIM86470.1 - 2.9 7.1 7.8 5.1 6.3 5.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Histone PF00125.19 EIM86471.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM86471.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIM86471.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIM86471.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIM86471.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIM86471.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EIM86472.1 - 3.9e-30 103.7 0.8 6.9e-30 102.9 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM86472.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIM86472.1 - 0.00066 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIM86472.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2360 PF10152.4 EIM86472.1 - 0.087 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CENP-T PF15511.1 EIM86472.1 - 0.1 11.8 1.4 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pyr_redox_2 PF07992.9 EIM86473.1 - 2.2e-16 60.3 0.0 6.6e-16 58.7 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM86473.1 - 1e-13 51.4 0.0 8.7e-11 42.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM86473.1 - 7.4e-09 34.9 2.7 0.00029 19.8 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM86473.1 - 1.2e-07 32.0 0.0 0.00027 21.0 0.0 3.2 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM86473.1 - 1.6e-07 31.2 0.1 0.00055 19.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM86473.1 - 0.00018 20.5 0.1 0.23 10.3 0.0 2.6 2 1 1 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM86473.1 - 0.00022 19.9 0.7 0.0027 16.4 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EIM86473.1 - 0.0014 18.6 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIM86473.1 - 0.011 15.9 0.7 5.4 7.3 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIM86473.1 - 0.014 15.4 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EIM86473.1 - 0.017 13.6 0.1 0.85 8.0 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 EIM86473.1 - 0.052 12.5 0.4 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EIM86473.1 - 0.073 12.1 1.1 0.99 8.4 0.2 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 EIM86473.1 - 0.54 9.0 4.5 1.2 7.9 0.1 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A SR-25 PF10500.4 EIM86474.1 - 0.0072 15.8 4.2 0.0072 15.8 2.9 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pirin PF02678.11 EIM86476.1 - 8.2e-28 96.4 0.5 1.7e-27 95.3 0.4 1.5 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EIM86476.1 - 5.6e-06 25.7 3.4 1.2e-05 24.7 0.6 2.2 2 0 0 2 2 2 1 Cupin domain DUF4596 PF15363.1 EIM86476.1 - 0.12 12.3 2.3 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) ATG27 PF09451.5 EIM86477.1 - 0.039 13.1 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Imm46 PF15585.1 EIM86477.1 - 0.044 13.8 0.2 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 46 Chromo PF00385.19 EIM86478.1 - 9.7e-12 44.3 0.4 9.7e-12 44.3 0.3 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EIM86478.1 - 7.9e-06 25.6 0.1 2.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain SAP PF02037.22 EIM86479.1 - 2.7e-06 26.7 0.4 6.7e-06 25.4 0.3 1.7 1 0 0 1 1 1 1 SAP domain zf-MYND PF01753.13 EIM86480.1 - 1.3e-09 37.7 10.9 2.3e-09 36.9 7.5 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM86480.1 - 0.2 11.5 6.8 0.43 10.4 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TFIIIC_delta PF12657.2 EIM86481.1 - 1.8e-24 86.3 5.5 3.2e-23 82.3 1.7 2.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EIM86481.1 - 9.8e-22 76.7 0.1 2.2e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex FdhE PF04216.7 EIM86481.1 - 0.03 14.0 0.7 0.053 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-ribbon_3 PF13248.1 EIM86481.1 - 0.27 10.5 3.4 0.47 9.7 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EIM86481.1 - 0.3 10.8 2.1 6.7 6.4 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pro-kuma_activ PF09286.6 EIM86482.1 - 2.4e-33 115.1 0.0 1.7e-32 112.4 0.0 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM86482.1 - 1.1e-09 37.9 3.9 1.7e-09 37.2 0.1 2.1 1 1 0 2 2 2 1 Subtilase family Ish1 PF10281.4 EIM86482.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Arginosuc_synth PF00764.14 EIM86483.1 - 1.1e-147 492.1 0.0 1.4e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EIM86483.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EIM86483.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EIM86483.1 - 0.095 11.2 0.0 0.17 10.4 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-RING_2 PF13639.1 EIM86484.1 - 1.5e-08 34.3 8.3 2.4e-08 33.6 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM86484.1 - 8.7e-07 28.5 5.9 1.4e-06 27.8 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM86484.1 - 2.9e-06 27.2 9.0 1e-05 25.4 6.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM86484.1 - 2.9e-06 26.9 5.9 4.9e-06 26.1 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM86484.1 - 1.4e-05 24.8 4.0 1.4e-05 24.8 2.8 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIM86484.1 - 3.2e-05 23.5 7.4 8.1e-05 22.2 5.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WEMBL PF05701.6 EIM86484.1 - 0.0002 19.9 6.1 0.00038 19.0 4.2 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light zf-RING_UBOX PF13445.1 EIM86484.1 - 0.00021 20.9 1.6 0.00021 20.9 1.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIM86484.1 - 0.00028 20.5 0.6 0.00056 19.6 0.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TMF_DNA_bd PF12329.3 EIM86484.1 - 0.01 15.6 8.2 0.01 15.6 5.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIM86484.1 - 0.049 13.2 3.2 0.08 12.5 2.2 1.3 1 0 0 1 1 1 0 IncA protein Baculo_IE-1 PF05290.6 EIM86484.1 - 0.053 13.2 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) PIN_4 PF13638.1 EIM86484.1 - 0.16 12.0 3.0 0.35 10.9 2.1 1.5 1 0 0 1 1 1 0 PIN domain Spc7 PF08317.6 EIM86484.1 - 0.31 9.6 4.7 0.47 9.0 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.8 EIM86484.1 - 0.58 9.1 3.3 0.85 8.6 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-rbx1 PF12678.2 EIM86484.1 - 1.1 9.3 5.4 0.41 10.7 0.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger DUF724 PF05266.9 EIM86484.1 - 1.5 8.4 15.7 0.016 14.8 5.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-MIZ PF02891.15 EIM86484.1 - 4.6 6.8 11.6 0.3 10.6 3.2 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger RINGv PF12906.2 EIM86485.1 - 1.4e-15 57.0 8.1 2.5e-15 56.2 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EIM86485.1 - 0.14 11.9 8.7 0.23 11.2 6.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EIM86485.1 - 1.9 8.3 4.7 3.7 7.4 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-AD PF07776.10 EIM86485.1 - 2.7 8.0 3.9 5.6 7.0 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-RING_4 PF14570.1 EIM86485.1 - 4.5 6.9 7.4 7.4 6.2 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EIM86485.1 - 8.2 6.5 7.4 15 5.6 5.1 1.4 1 0 0 1 1 1 0 RING-like domain HNH_2 PF13391.1 EIM86487.1 - 0.00064 19.4 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Peptidase_C15 PF01470.12 EIM86488.1 - 2.3e-09 37.4 0.0 0.00075 19.3 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase Pkinase PF00069.20 EIM86489.1 - 5.8e-07 28.9 0.0 9.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86489.1 - 0.0051 15.9 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FbpA PF05833.6 EIM86489.1 - 0.15 10.5 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) zf-MYND PF01753.13 EIM86491.1 - 8.7e-08 31.9 10.7 2.2e-07 30.6 7.4 1.7 1 0 0 1 1 1 1 MYND finger UbiA PF01040.13 EIM86493.1 - 3e-23 82.3 17.7 5.5e-23 81.5 12.3 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family RRM_1 PF00076.17 EIM86494.1 - 5.5e-15 54.7 0.0 8.9e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM86494.1 - 9.7e-12 44.6 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM86494.1 - 1.8e-06 27.6 0.0 4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S7 PF00949.16 EIM86494.1 - 0.061 12.7 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease RRM_3 PF08777.6 EIM86494.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Methyltransf_16 PF10294.4 EIM86495.1 - 5.3e-20 71.5 0.0 4.2e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EIM86495.1 - 0.0038 16.9 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIM86495.1 - 0.038 13.0 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EIM86495.1 - 0.05 14.1 0.0 0.085 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_molyb PF00174.14 EIM86496.1 - 6.7e-48 162.2 0.0 1.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIM86496.1 - 1.7e-25 89.1 1.7 3.1e-25 88.3 1.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF3414 PF11894.3 EIM86496.1 - 0.28 8.0 0.1 0.36 7.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Oxidored_molyb PF00174.14 EIM86497.1 - 1.1e-47 161.5 0.0 2.6e-47 160.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIM86497.1 - 1.8e-24 85.8 0.8 3e-24 85.1 0.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.20 EIM86499.1 - 4.9e-50 170.1 0.0 6.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86499.1 - 3.5e-25 88.5 0.0 4.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM86499.1 - 2e-06 26.9 0.0 9.7e-06 24.7 0.0 2.0 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EIM86499.1 - 0.00051 19.1 0.1 0.00088 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM86499.1 - 0.00079 19.2 0.2 0.74 9.5 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIM86499.1 - 0.0043 16.4 0.3 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Cellulase PF00150.13 EIM86500.1 - 2.2e-13 50.0 1.2 3.5e-13 49.3 0.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PI3Ka PF00613.15 EIM86502.1 - 2.2e-53 180.2 0.4 3.6e-53 179.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EIM86502.1 - 7e-41 140.2 0.0 1.9e-39 135.5 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EIM86502.1 - 1.1e-39 135.4 0.0 1.9e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 EIM86502.1 - 3.3e-05 23.6 0.0 9.4e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain RTC4 PF14474.1 EIM86504.1 - 7.4e-21 74.3 0.0 8.2e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain Ribonuc_red_sm PF00268.16 EIM86506.1 - 1.1e-120 401.9 0.7 1.3e-120 401.6 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-MYND PF01753.13 EIM86507.1 - 1.6e-05 24.6 9.6 4e-05 23.3 6.6 1.7 1 0 0 1 1 1 1 MYND finger SPDY PF03771.11 EIM86507.1 - 0.13 11.7 1.1 5.6 6.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF317) PTS_2-RNA PF01885.11 EIM86509.1 - 2.1e-56 190.1 0.1 2.6e-56 189.9 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pirin PF02678.11 EIM86512.1 - 2.2e-11 43.5 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EIM86512.1 - 0.015 14.8 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Cupin domain KAR9 PF08580.5 EIM86513.1 - 6.1 4.9 5.7 6.9 4.8 3.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2718 PF10918.3 EIM86514.1 - 0.17 11.9 0.2 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) SET PF00856.23 EIM86515.1 - 3.3e-15 56.7 0.2 2.6e-14 53.8 0.0 2.6 2 1 0 2 2 2 1 SET domain SET PF00856.23 EIM86516.1 - 1.6e-07 31.7 0.0 0.00013 22.2 0.0 2.9 3 0 0 3 3 3 2 SET domain MGC-24 PF05283.6 EIM86516.1 - 4.4 7.0 7.7 3.1 7.5 2.0 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) GATA PF00320.22 EIM86518.1 - 2.9e-14 52.0 2.3 6.9e-14 50.8 1.6 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF383 PF04063.9 EIM86519.1 - 6.9e-56 188.8 0.0 1.5e-55 187.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EIM86519.1 - 4.3e-20 71.0 0.1 6.1e-19 67.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF2183 PF09949.4 EIM86520.1 - 6.2e-28 96.6 0.0 1.3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) ATG16 PF08614.6 EIM86521.1 - 0.0052 16.6 11.3 0.0052 16.6 7.8 3.4 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) BRE1 PF08647.6 EIM86521.1 - 0.047 13.6 12.1 0.11 12.4 0.9 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KLRAQ PF10205.4 EIM86521.1 - 2.5 8.1 15.5 0.054 13.5 4.8 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.6 EIM86521.1 - 5.6 5.5 21.2 0.34 9.5 7.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.15 EIM86521.1 - 6 5.8 39.8 0.07 12.2 0.4 4.0 2 1 2 4 4 4 0 Tropomyosin AAA_13 PF13166.1 EIM86521.1 - 6.7 5.0 12.8 10 4.4 8.8 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EIM86521.1 - 7.8 4.2 12.8 14 3.3 8.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTB PF00651.26 EIM86522.1 - 0.0061 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM86523.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DNA_pol3_tau_5 PF12170.3 EIM86523.1 - 0.041 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha DEAD PF00270.24 EIM86524.1 - 1.4e-45 154.8 0.0 4.5e-45 153.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM86524.1 - 1.1e-26 92.4 0.1 2.3e-26 91.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM86524.1 - 0.013 15.3 0.0 0.045 13.5 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 EIM86524.1 - 0.023 14.4 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S28e DUF1253 PF06862.7 EIM86524.1 - 0.067 11.5 0.0 0.13 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) EIIA-man PF03610.11 EIM86524.1 - 0.16 12.0 0.1 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 PTS system fructose IIA component BTB PF00651.26 EIM86526.1 - 8.5e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM86527.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DPBB_1 PF03330.13 EIM86528.1 - 1.3e-07 31.5 0.5 2.4e-07 30.6 0.4 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM86528.1 - 0.0048 16.5 0.4 0.011 15.4 0.2 1.7 2 0 0 2 2 2 1 Barwin family DUF2263 PF10021.4 EIM86530.1 - 3.4e-17 62.8 0.0 6.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.13 EIM86531.1 - 3.2e-25 88.4 0.1 6.2e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EIM86532.1 - 1.5e-22 79.7 0.0 2.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ETRAMP PF09716.5 EIM86533.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Gly-zipper_Omp PF13488.1 EIM86533.1 - 0.29 10.8 3.3 0.53 9.9 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper OPT PF03169.10 EIM86534.1 - 2.1e-132 442.6 44.6 2.4e-132 442.4 30.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.13 EIM86535.1 - 7.8e-20 70.8 0.0 1.5e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86535.1 - 2.2e-05 24.2 10.1 2.2e-05 24.2 7.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DegS PF05384.6 EIM86535.1 - 0.091 11.9 0.1 0.21 10.8 0.1 1.5 2 0 0 2 2 2 0 Sensor protein DegS RTA1 PF04479.8 EIM86536.1 - 5.6e-35 120.8 7.7 1e-34 120.0 5.3 1.3 1 0 0 1 1 1 1 RTA1 like protein TctB PF07331.6 EIM86536.1 - 7.5 6.1 19.3 0.48 10.0 3.7 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MMR_HSR1 PF01926.18 EIM86537.1 - 2e-12 47.1 0.0 3.7e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIM86537.1 - 0.0067 16.2 0.0 1.6 8.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 EIM86537.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIM86537.1 - 0.06 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EIM86537.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EIM86537.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase WD40 PF00400.27 EIM86538.1 - 3.6e-74 242.2 21.9 1.1e-12 47.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIM86538.1 - 1.8e-10 40.8 0.1 2.8e-05 23.9 0.0 3.7 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIM86538.1 - 2.8e-06 25.7 6.5 0.019 13.1 0.2 4.8 1 1 3 5 5 5 3 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EIM86538.1 - 0.00012 21.5 2.5 0.00055 19.3 0.4 2.5 1 1 2 3 3 3 1 Cytolethal distending toxin A/C family DUF1513 PF07433.6 EIM86538.1 - 0.00021 20.3 0.6 1.3 7.8 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.1 EIM86538.1 - 0.00045 18.7 0.0 0.0046 15.4 0.0 2.1 1 1 1 2 2 2 1 Oligogalacturonate lyase RicinB_lectin_2 PF14200.1 EIM86538.1 - 0.0048 17.2 0.9 0.43 10.9 0.1 3.2 2 2 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.11 EIM86538.1 - 0.0072 14.6 0.0 0.047 11.9 0.0 2.3 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.1 EIM86538.1 - 0.028 13.5 1.4 1.5 7.8 0.1 3.1 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 EIM86538.1 - 0.042 12.6 0.1 1 8.0 0.0 2.2 1 1 0 2 2 2 0 Coatomer WD associated region Ricin_B_lectin PF00652.17 EIM86538.1 - 0.12 12.3 3.4 0.39 10.7 0.5 2.5 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Mito_fiss_reg PF05308.6 EIM86538.1 - 5.7 6.2 6.0 7.9 5.7 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator GDNF PF02351.11 EIM86539.1 - 0.097 13.1 0.7 0.097 13.1 0.5 1.6 2 0 0 2 2 2 0 GDNF/GAS1 domain Clp1 PF06807.9 EIM86540.1 - 1.2e-09 38.2 0.0 5.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EIM86540.1 - 2.8e-08 33.5 0.0 5.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EIM86540.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EIM86540.1 - 0.045 13.6 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIM86540.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Dicty_REP PF05086.7 EIM86540.1 - 2.9 5.5 3.5 3.9 5.0 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 EIM86541.1 - 1.3e-84 275.2 22.0 1.4e-12 46.9 0.4 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIM86541.1 - 2e-08 32.8 6.2 0.0006 18.0 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EIM86541.1 - 3.1e-08 33.5 0.1 5.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Proteasome_A_N PF10584.4 EIM86541.1 - 0.0021 17.3 0.3 2.2 7.7 0.0 2.8 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EIM86541.1 - 0.0034 16.1 2.2 3.7 6.1 0.0 3.5 3 1 1 4 4 4 3 Nup133 N terminal like IKI3 PF04762.7 EIM86541.1 - 0.053 11.3 0.0 0.1 10.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family RabGAP-TBC PF00566.13 EIM86543.1 - 3e-44 151.0 0.0 5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EIM86543.1 - 8.7e-05 22.5 3.2 0.0065 16.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EIM86543.1 - 9.4e-05 21.9 4.6 0.0018 18.0 0.2 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIM86543.1 - 0.0002 20.3 1.4 0.0013 17.8 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIM86543.1 - 0.018 14.6 2.0 0.066 12.8 0.4 2.5 1 1 1 2 2 2 0 EF-hand domain pair GRAM PF02893.15 EIM86543.1 - 0.029 13.8 0.0 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 GRAM domain EF-hand_5 PF13202.1 EIM86543.1 - 0.037 13.3 0.1 0.12 11.7 0.1 1.9 1 0 0 1 1 1 0 EF hand ORC6 PF05460.8 EIM86544.1 - 0.25 10.3 3.9 0.37 9.8 2.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MFS_1 PF07690.11 EIM86546.1 - 1.7e-30 105.9 46.4 2.7e-30 105.2 30.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF373 PF04123.8 EIM86546.1 - 6.7 5.6 13.3 1.3 7.9 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF2183 PF09949.4 EIM86547.1 - 8e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) BTB PF00651.26 EIM86548.1 - 6.8e-07 29.2 0.1 2.7e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM86549.1 - 4.9e-09 36.1 0.0 7.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_ISL3 PF13542.1 EIM86549.1 - 0.074 12.2 0.1 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DNA_pol_B PF00136.16 EIM86550.1 - 4.3e-113 378.5 0.0 6.4e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EIM86550.1 - 5.7e-57 192.1 0.0 9.8e-57 191.3 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EIM86550.1 - 3.8e-26 91.7 0.0 8.8e-26 90.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EIM86550.1 - 1.1e-15 57.2 7.5 3.4e-15 55.5 5.2 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Flavin_Reduct PF01613.13 EIM86551.1 - 7.1e-28 97.3 0.1 9.8e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF485 PF04341.7 EIM86552.1 - 5 6.9 7.0 4.9 6.9 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF485 zf-DNL PF05180.7 EIM86554.1 - 6e-28 96.3 0.2 9e-28 95.7 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger K1377 PF15352.1 EIM86554.1 - 0.079 10.8 0.3 0.1 10.5 0.2 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Glutaredoxin PF00462.19 EIM86555.1 - 1.3e-15 57.0 0.0 1.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Sds3 PF08598.6 EIM86556.1 - 3.4e-09 36.5 0.0 7.9e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Sds3-like AICARFT_IMPCHas PF01808.13 EIM86557.1 - 6.3e-105 350.7 0.0 8.5e-105 350.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EIM86557.1 - 6.6e-24 83.6 0.0 1.8e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain adh_short PF00106.20 EIM86557.1 - 3.5e-23 82.3 0.1 6.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM86557.1 - 1.1e-09 38.2 0.0 2.5e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIM86557.1 - 0.0019 16.9 0.0 0.0042 15.8 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM86557.1 - 0.0069 16.4 0.5 0.056 13.4 0.0 2.6 3 0 0 3 3 3 1 NADH(P)-binding AraC_binding_2 PF14525.1 EIM86557.1 - 0.021 14.3 0.1 0.092 12.3 0.1 1.9 2 0 0 2 2 2 0 AraC-binding-like domain Ribosomal_L3 PF00297.17 EIM86557.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L3 Epimerase PF01370.16 EIM86557.1 - 0.11 11.9 0.0 0.4 10.0 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.2 EIM86558.1 - 2.3e-05 24.0 0.0 9.7e-05 22.0 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM86559.1 - 2.1e-05 24.1 0.1 8.6e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 F-box-like Cluap1 PF10234.4 EIM86559.1 - 0.042 13.0 1.4 0.062 12.4 1.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TPR_MLP1_2 PF07926.7 EIM86559.1 - 0.44 10.2 4.8 0.7 9.6 3.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3832 PF12909.2 EIM86560.1 - 0.0074 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3832) ABM PF03992.11 EIM86562.1 - 4.8e-10 39.3 0.0 6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ACC_central PF08326.7 EIM86563.1 - 2e-211 703.8 0.0 2.7e-211 703.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EIM86563.1 - 1.4e-163 544.8 0.0 1.8e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EIM86563.1 - 2.6e-50 170.6 0.0 4.9e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIM86563.1 - 1.8e-25 89.2 0.0 3.5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIM86563.1 - 3.8e-21 75.0 0.0 4.8e-20 71.5 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIM86563.1 - 1e-13 50.7 0.0 2.1e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIM86563.1 - 2.1e-12 47.1 0.0 4.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIM86563.1 - 1.4e-08 33.8 0.0 1.5e-05 23.9 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EIM86563.1 - 0.0024 17.7 0.0 0.008 16.0 0.0 1.9 2 0 0 2 2 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIM86563.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIM86563.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Kinesin PF00225.18 EIM86564.1 - 1.5e-103 346.0 0.3 2.2e-103 345.4 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain TPR_MLP1_2 PF07926.7 EIM86564.1 - 3.5e-05 23.5 9.0 3.5e-05 23.5 6.2 3.0 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 EIM86564.1 - 0.018 15.0 3.1 0.018 15.0 2.2 3.2 3 1 0 3 3 2 0 Proteins of 100 residues with WXG IncA PF04156.9 EIM86564.1 - 0.029 13.9 26.9 0.046 13.3 10.0 2.5 1 1 1 2 2 2 0 IncA protein WEMBL PF05701.6 EIM86564.1 - 0.036 12.5 22.8 0.066 11.6 15.8 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EIM86564.1 - 0.052 12.7 14.9 1.2 8.2 1.0 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EIM86564.1 - 0.15 11.8 20.1 0.55 10.0 3.0 2.8 1 1 1 2 2 2 0 Tropomyosin like Filament PF00038.16 EIM86564.1 - 0.25 10.7 23.5 48 3.2 16.3 2.5 1 1 0 1 1 1 0 Intermediate filament protein Bacillus_HBL PF05791.6 EIM86564.1 - 0.29 10.4 9.1 0.06 12.7 0.3 2.9 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Med9 PF07544.8 EIM86564.1 - 1.1 9.0 13.7 7.2 6.4 1.0 3.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Macoilin PF09726.4 EIM86564.1 - 1.2 7.3 19.7 5.4 5.1 13.6 2.0 1 1 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 EIM86564.1 - 1.3 9.1 13.6 1.5 8.9 2.1 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EIM86564.1 - 2.6 7.9 23.4 2.5 8.0 2.3 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIM86564.1 - 2.8 8.3 24.7 1.6 9.1 1.7 5.5 4 1 2 6 6 5 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 EIM86564.1 - 4.1 7.7 16.3 1.6 9.0 2.5 3.6 1 1 2 3 3 3 0 Snapin/Pallidin Spc7 PF08317.6 EIM86564.1 - 4.1 5.9 20.8 4.8 5.7 10.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 EIM86564.1 - 4.1 6.2 22.1 0.85 8.5 6.9 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 EIM86564.1 - 4.3 7.3 26.1 0.12 12.3 3.0 3.4 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 EIM86564.1 - 6.1 5.1 17.0 2.7 6.3 9.4 2.1 2 1 0 2 2 2 0 AAA domain ING PF12998.2 EIM86564.1 - 8.7 6.6 10.2 0.32 11.2 0.8 3.0 4 0 0 4 4 2 0 Inhibitor of growth proteins N-terminal histone-binding ATG16 PF08614.6 EIM86564.1 - 9.2 6.0 28.8 4 7.2 11.7 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 EIM86564.1 - 9.2 6.0 8.8 14 5.5 1.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2937 PF11157.3 EIM86564.1 - 9.3 5.5 8.4 4.4 6.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Peptidase_C14 PF00656.17 EIM86565.1 - 4.2e-21 75.7 0.0 8.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Peptidase_M20 PF01546.23 EIM86566.1 - 8.9e-21 74.2 0.5 2.5e-20 72.7 0.4 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM86566.1 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DAP3 PF10236.4 EIM86567.1 - 5.7e-70 235.6 0.0 6.9e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIM86567.1 - 3.2e-07 30.5 0.1 7.9e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIM86567.1 - 0.0018 17.9 0.0 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EIM86567.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EIM86567.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EIM86567.1 - 0.035 13.4 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.1 EIM86567.1 - 0.11 11.0 0.0 1.8 7.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain VHS PF00790.14 EIM86568.1 - 7.1e-33 113.2 0.1 1.5e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EIM86568.1 - 1.9e-15 56.1 0.1 3.2e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM86568.1 - 1.4e-14 53.3 0.3 2.8e-14 52.3 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EIM86568.1 - 3.4e-14 51.9 0.0 5.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain GAT PF03127.9 EIM86568.1 - 9.6e-07 28.7 1.4 2.9e-06 27.1 1.0 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 EIM86568.1 - 0.0015 17.9 1.0 0.0038 16.6 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Gag_spuma PF03276.9 EIM86568.1 - 0.029 12.7 3.3 0.046 12.0 2.3 1.3 1 0 0 1 1 1 0 Spumavirus gag protein EzrA PF06160.7 EIM86568.1 - 0.029 12.5 0.4 0.049 11.8 0.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF445 PF04286.7 EIM86568.1 - 0.082 12.4 1.0 4.7 6.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF445) UNC45-central PF11701.3 EIM86568.1 - 0.09 12.4 0.5 0.17 11.5 0.4 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central UQ_con PF00179.21 EIM86569.1 - 6.7e-17 61.2 0.0 7.3e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIM86569.1 - 0.0042 16.9 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIM86569.1 - 0.032 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain Asp PF00026.18 EIM86570.1 - 4.4e-75 252.8 15.6 6e-75 252.4 10.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIM86570.1 - 0.00016 21.2 0.0 0.00047 19.7 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIM86570.1 - 0.0013 18.6 11.0 0.0018 18.2 4.7 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF1214 PF06742.6 EIM86570.1 - 0.069 13.6 0.8 7.9 7.0 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1214) Opi1 PF08618.5 EIM86571.1 - 2.5e-68 230.9 27.0 1e-57 195.9 3.4 4.1 3 1 0 3 3 3 2 Transcription factor Opi1 Perilipin PF03036.11 EIM86571.1 - 2.3e-06 26.7 0.0 5.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Perilipin family REF PF05755.7 EIM86571.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) zf-MYND PF01753.13 EIM86572.1 - 2.1e-11 43.4 9.0 5.8e-11 42.0 6.2 1.7 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM86572.1 - 0.00013 21.7 1.2 0.00013 21.7 0.8 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 EIM86572.1 - 1.8 7.9 6.6 5.4 6.4 4.6 1.9 1 1 0 1 1 1 0 Life-span regulatory factor Ribosomal_L35Ae PF01247.13 EIM86573.1 - 8e-43 144.1 1.3 9e-43 143.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIM86573.1 - 0.00052 19.8 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain ArgJ PF01960.13 EIM86574.1 - 1.2e-136 455.1 0.0 1.4e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 ArgJ family F-box-like PF12937.2 EIM86575.1 - 1.9e-07 30.6 0.7 5.4e-07 29.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like Exo_endo_phos PF03372.18 EIM86576.1 - 1.2e-11 45.0 0.0 2.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIM86576.1 - 3.5e-10 39.5 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EIM86576.1 - 1.3e-05 25.0 3.8 0.0016 18.3 0.1 2.6 2 0 0 2 2 2 2 GRF zinc finger Spuma_A9PTase PF03539.9 EIM86576.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) zf-C2H2_jaz PF12171.3 EIM86577.1 - 1.2e-09 37.9 4.5 2.3e-09 37.0 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM86577.1 - 0.016 15.3 2.7 0.03 14.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIM86577.1 - 0.04 14.0 2.0 0.04 14.0 1.4 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIM86577.1 - 0.075 13.4 0.7 0.2 12.0 0.5 1.8 1 1 0 1 1 1 0 Zinc finger, C2H2 type IQ PF00612.22 EIM86577.1 - 6.8 6.6 7.7 2.6 7.9 0.5 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif DNA_pol_A_exo1 PF01612.15 EIM86578.1 - 2.4e-14 53.2 0.0 4.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Rubi_NSP_C PF12601.3 EIM86578.1 - 0.0092 15.8 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 Rubivirus non-structural protein DNA_pol_A_exo1 PF01612.15 EIM86579.1 - 2.7e-13 49.7 0.1 6.2e-12 45.3 0.1 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Oxidored_molyb PF00174.14 EIM86580.1 - 6e-51 172.2 0.0 9.3e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIM86580.1 - 4e-11 42.6 0.0 1.1e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain GATA PF00320.22 EIM86581.1 - 5.5e-18 64.0 3.5 9.2e-18 63.3 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIM86581.1 - 0.0047 16.2 1.1 0.0078 15.5 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.13 EIM86581.1 - 0.016 14.9 0.2 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DZR PF12773.2 EIM86581.1 - 0.034 13.9 1.4 0.093 12.5 0.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EIM86581.1 - 0.045 13.8 1.1 0.081 13.0 0.8 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-FCS PF06467.9 EIM86581.1 - 0.075 12.6 0.9 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif eIF-5_eIF-2B PF01873.12 EIM86581.1 - 0.11 12.1 0.6 0.16 11.6 0.2 1.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ADK_lid PF05191.9 EIM86581.1 - 0.14 11.8 0.5 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid UPF0547 PF10571.4 EIM86581.1 - 0.18 11.5 0.6 18 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EIM86581.1 - 0.29 10.3 5.7 0.94 8.7 0.3 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIM86581.1 - 0.34 10.4 3.1 1.8 8.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GSu_C4xC__C2xCH PF09698.5 EIM86581.1 - 7.5 6.8 7.0 34 4.7 4.9 2.1 1 1 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) GATA PF00320.22 EIM86582.1 - 2.2e-12 46.1 5.7 3e-12 45.6 3.9 1.2 1 0 0 1 1 1 1 GATA zinc finger RRN7 PF11781.3 EIM86582.1 - 0.12 11.8 0.6 0.27 10.7 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EIM86582.1 - 0.15 11.8 2.9 0.45 10.3 1.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EIM86582.1 - 0.28 11.3 3.2 0.53 10.4 2.2 1.4 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF3736 PF12540.3 EIM86582.1 - 0.75 10.0 8.0 0.92 9.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) zf-ribbon_3 PF13248.1 EIM86582.1 - 5.3 6.3 6.7 62 2.9 4.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Amidohydro_4 PF13147.1 EIM86583.1 - 1.1e-18 68.2 4.9 1.4e-10 41.6 0.1 3.8 3 1 1 4 4 4 2 Amidohydrolase Amidohydro_5 PF13594.1 EIM86583.1 - 1.1e-11 44.3 0.6 6.1e-11 41.9 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM86583.1 - 2.5e-11 43.8 0.1 6.9e-08 32.5 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIM86583.1 - 1.5e-08 34.3 0.1 3.7e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family PsaM PF07465.8 EIM86585.1 - 0.28 10.8 3.0 0.64 9.6 2.1 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Zds_C PF08632.5 EIM86586.1 - 4.7e-22 77.1 0.6 8.4e-22 76.3 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1510 PF07423.6 EIM86586.1 - 0.44 9.8 15.8 0.11 11.7 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EIM86586.1 - 4.6 4.8 6.1 0.45 8.1 0.3 1.8 2 0 0 2 2 2 0 Ycf1 Cys_Met_Meta_PP PF01053.15 EIM86587.1 - 1.3e-136 454.9 0.0 1.5e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIM86587.1 - 5.3e-13 48.7 0.3 1.1e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIM86587.1 - 7.1e-11 41.6 0.1 1.4e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIM86587.1 - 6.6e-09 34.9 1.5 9.7e-09 34.4 0.3 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIM86587.1 - 4.9e-05 22.6 0.0 0.0001 21.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EIM86587.1 - 0.0055 15.0 0.1 0.007 14.7 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EIM86587.1 - 0.095 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Adhesin_P1 PF03257.8 EIM86588.1 - 0.11 12.7 0.6 0.15 12.3 0.0 1.5 2 0 0 2 2 2 0 Mycoplasma adhesin P1 DUF2781 PF10914.3 EIM86589.1 - 2.9e-30 105.0 10.2 3.5e-30 104.7 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF2628 PF10947.3 EIM86589.1 - 0.061 13.1 4.6 0.61 9.8 3.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Peptidase_M56 PF05569.6 EIM86590.1 - 0.15 11.0 0.1 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 PH_10 PF15411.1 EIM86591.1 - 1.6e-26 92.7 0.0 2.9e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EIM86591.1 - 5.2e-06 26.1 1.5 1.2e-05 24.9 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIM86591.1 - 0.0023 17.6 0.4 0.0065 16.1 0.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain VWA_3 PF13768.1 EIM86591.1 - 0.0023 17.6 1.6 0.011 15.4 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EIM86591.1 - 0.0065 16.1 0.7 0.012 15.2 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM86591.1 - 0.013 15.5 0.6 0.068 13.2 0.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger PH PF00169.24 EIM86591.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 PH domain zf-C3HC4_2 PF13923.1 EIM86591.1 - 0.14 12.2 0.7 0.33 11.0 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM86591.1 - 0.18 11.5 0.1 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nsp1_C PF05064.8 EIM86592.1 - 0.02 14.5 0.1 12 5.5 0.0 3.2 3 0 0 3 3 3 0 Nsp1-like C-terminal region Lebercilin PF15619.1 EIM86592.1 - 0.067 12.6 4.9 0.05 13.0 2.3 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMCO5 PF14992.1 EIM86592.1 - 0.3 10.1 3.2 0.34 9.9 1.5 1.5 1 1 0 1 1 1 0 TMCO5 family AAA_12 PF13087.1 EIM86593.1 - 1.8e-36 125.3 0.0 4.6e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM86593.1 - 1.7e-26 93.2 0.0 7.6e-26 91.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM86593.1 - 3.8e-10 39.6 0.1 1.2e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM86593.1 - 2e-07 30.6 0.0 5.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain zf-RING_2 PF13639.1 EIM86593.1 - 0.00059 19.6 2.6 0.0011 18.7 0.1 2.5 2 0 0 2 2 2 1 Ring finger domain DUF2075 PF09848.4 EIM86593.1 - 0.0014 17.6 0.0 0.023 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EIM86593.1 - 0.002 18.1 0.0 0.0078 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 EIM86593.1 - 0.018 15.1 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.1 EIM86593.1 - 0.07 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIM86593.1 - 0.072 12.8 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EIM86593.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIM86593.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EIM86593.1 - 0.19 10.9 0.1 0.59 9.3 0.1 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-C3HC4_3 PF13920.1 EIM86593.1 - 4.2 7.1 11.5 0.92 9.2 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) E1-E2_ATPase PF00122.15 EIM86594.1 - 2.4e-53 180.5 1.5 5.7e-53 179.2 1.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIM86594.1 - 2.5e-34 119.5 2.4 2.5e-34 119.5 0.7 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIM86594.1 - 3.1e-23 81.6 0.0 2.4e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 EIM86594.1 - 1.7e-12 47.9 0.0 4.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIM86594.1 - 3.2e-05 23.6 0.6 0.0099 15.4 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peptidase_M91 PF14891.1 EIM86595.1 - 0.02 14.9 0.4 0.031 14.3 0.3 1.5 1 1 0 1 1 1 0 Effector protein Aldedh PF00171.17 EIM86596.1 - 1.1e-12 47.1 4.9 1.1e-09 37.1 2.9 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family SHNi-TPR PF10516.4 EIM86597.1 - 5.3e-13 47.9 0.1 8.6e-11 40.8 0.0 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EIM86597.1 - 2.7e-08 33.3 2.6 0.0042 16.6 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIM86597.1 - 9.2e-08 31.9 14.2 0.00042 20.2 0.4 3.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86597.1 - 2e-05 23.9 0.4 0.14 11.8 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIM86597.1 - 0.00032 20.3 8.5 0.23 11.4 0.6 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86597.1 - 0.0085 16.7 13.6 0.08 13.6 1.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86597.1 - 0.16 12.2 17.1 0.23 11.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM86597.1 - 0.98 9.3 5.9 1.1 9.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM86597.1 - 3.8 7.5 5.7 9.7 6.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 EIM86598.1 - 0.00055 19.4 0.1 23 4.7 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) Exotox-A_cataly PF09009.5 EIM86600.1 - 0.00065 18.6 1.0 0.005 15.7 0.1 2.1 1 1 1 2 2 2 2 Exotoxin A catalytic MS_channel PF00924.13 EIM86601.1 - 2.2e-18 66.3 2.2 4.2e-18 65.4 1.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIM86601.1 - 7.7e-06 24.8 0.1 1.7e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIM86601.1 - 3.2e-05 23.4 0.1 0.00011 21.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EIM86601.1 - 0.00034 20.6 0.6 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EIM86601.1 - 0.0012 18.1 0.1 0.0033 16.6 0.1 1.7 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.1 EIM86601.1 - 0.25 11.6 2.0 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_membrane PF00664.18 EIM86602.1 - 8.2e-69 232.0 34.8 2.2e-38 132.2 9.8 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM86602.1 - 4.9e-52 175.8 0.0 5.5e-31 107.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EIM86602.1 - 7.9e-09 35.0 0.0 0.0045 16.2 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIM86602.1 - 4.1e-05 23.6 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM86602.1 - 6.1e-05 22.4 0.2 0.04 13.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 EIM86602.1 - 6.3e-05 23.4 1.5 0.3 11.5 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 EIM86602.1 - 0.00032 20.7 0.4 1.5 8.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EIM86602.1 - 0.00052 19.9 0.5 0.9 9.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EIM86602.1 - 0.0031 16.6 0.0 0.62 9.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EIM86602.1 - 0.0046 16.3 0.1 3.7 6.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EIM86602.1 - 0.0074 16.1 2.4 1.4 8.7 0.0 2.7 3 0 0 3 3 2 2 Dynamin family T2SE PF00437.15 EIM86602.1 - 0.0092 14.9 0.0 5 5.9 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.1 EIM86602.1 - 0.025 14.9 0.1 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIM86602.1 - 0.042 13.0 0.7 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EIM86602.1 - 0.059 12.9 0.2 5.3 6.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EIM86602.1 - 0.078 12.4 2.5 0.4 10.0 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 EIM86602.1 - 0.13 10.8 1.1 0.29 9.6 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 EIM86602.1 - 0.18 11.9 3.2 4.9 7.3 0.2 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EIM86602.1 - 0.3 10.8 5.1 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 PRK PF00485.13 EIM86602.1 - 7.8 5.9 5.7 10 5.5 0.1 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Peptidase_C12 PF01088.16 EIM86603.1 - 5.9e-57 192.2 0.0 8.2e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NAD_binding_8 PF13450.1 EIM86605.1 - 3.6e-09 36.5 0.0 8.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM86605.1 - 5.8e-07 29.7 0.0 4e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM86605.1 - 6.2e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIM86605.1 - 8.9e-05 21.6 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM86605.1 - 0.00012 21.9 0.0 0.00032 20.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM86605.1 - 0.00034 19.1 0.1 0.00065 18.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIM86605.1 - 0.00035 19.7 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIM86605.1 - 0.002 17.0 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM86605.1 - 0.023 13.5 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UPF0180 PF03698.8 EIM86605.1 - 0.033 14.0 0.0 0.31 10.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) NAD_binding_9 PF13454.1 EIM86605.1 - 0.051 13.3 0.1 0.34 10.6 0.0 2.4 4 0 0 4 4 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EIM86605.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EIM86606.1 - 3.6e-19 69.1 0.0 5.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM86606.1 - 2.6e-08 33.1 0.1 1.3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EIM86606.1 - 4.6e-08 33.2 0.7 2.2e-07 31.0 0.5 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM86606.1 - 1.2e-07 30.7 0.2 5e-07 28.7 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIM86606.1 - 0.0068 16.3 1.5 0.25 11.2 1.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM86606.1 - 0.013 14.4 0.1 0.028 13.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1640 PF07798.6 EIM86607.1 - 5.5e-63 212.1 7.0 6.6e-63 211.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Guanylate_kin PF00625.16 EIM86608.1 - 5.1e-63 211.8 0.0 6.9e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EIM86608.1 - 2e-08 34.4 0.0 7.7e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EIM86608.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM86608.1 - 2.4e-05 24.4 0.0 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIM86608.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM86608.1 - 0.00092 18.4 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIM86608.1 - 0.0014 19.4 0.1 0.0027 18.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIM86608.1 - 0.0038 17.1 0.0 0.0064 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIM86608.1 - 0.0059 16.7 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 EIM86608.1 - 0.0059 15.6 0.0 0.088 11.7 0.0 2.0 1 1 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 EIM86608.1 - 0.0064 16.2 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIM86608.1 - 0.0064 16.7 0.2 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIM86608.1 - 0.0071 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EIM86608.1 - 0.0083 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.10 EIM86608.1 - 0.0093 14.6 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EIM86608.1 - 0.0094 15.6 0.0 0.096 12.3 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIM86608.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 EIM86608.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EIM86608.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIM86608.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EIM86608.1 - 0.026 14.7 0.0 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EIM86608.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.7 EIM86608.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.14 EIM86608.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.20 EIM86609.1 - 5.6e-65 219.0 0.0 7.1e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86609.1 - 8.4e-36 123.3 0.0 1.2e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM86609.1 - 3.1e-06 26.3 0.0 5.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM86609.1 - 0.0014 18.3 0.3 0.003 17.3 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM86609.1 - 0.051 12.6 0.1 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_M PF01068.16 EIM86610.1 - 1.8e-24 86.2 0.0 2.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIM86610.1 - 9.9e-09 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus SAICAR_synt PF01259.13 EIM86611.1 - 4.5e-71 238.8 0.0 2.3e-38 131.7 0.1 2.0 1 1 1 2 2 2 2 SAICAR synthetase zf-ZPR1 PF03367.8 EIM86612.1 - 8.2e-100 330.6 0.3 4.3e-48 162.5 0.0 4.0 3 1 0 3 3 3 3 ZPR1 zinc-finger domain UPF0547 PF10571.4 EIM86612.1 - 0.0053 16.4 2.4 4.6 7.0 0.1 3.3 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 HypA PF01155.14 EIM86612.1 - 0.051 13.2 1.3 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EIM86612.1 - 0.74 9.5 3.4 53 3.5 0.0 3.5 4 0 0 4 4 4 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 EIM86612.1 - 0.75 9.3 4.1 33 4.0 0.1 3.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-dskA_traR PF01258.12 EIM86612.1 - 1.4 8.7 0.0 1.4 8.7 0.0 4.2 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.5 EIM86612.1 - 1.4 8.9 6.6 3.9 7.5 0.0 3.6 3 1 1 4 4 4 0 Zinc ribbon domain DZR PF12773.2 EIM86612.1 - 1.9 8.3 6.1 3.7 7.4 0.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EIM86612.1 - 6.2 6.1 5.7 70 2.8 1.6 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Nup35_RRM PF05172.8 EIM86613.1 - 6.5e-10 38.6 0.0 2.2e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EIM86613.1 - 9e-05 22.1 0.0 0.0004 20.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif UAA PF08449.6 EIM86614.1 - 6.8e-71 238.6 9.6 8.6e-71 238.3 6.7 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIM86614.1 - 0.0047 16.5 8.2 0.0047 16.5 5.7 2.6 1 1 1 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EIM86614.1 - 0.0079 15.3 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EIM86614.1 - 0.5 10.4 21.5 3.9 7.5 4.6 3.3 2 2 0 2 2 2 0 EamA-like transporter family Ribosomal_L28e PF01778.12 EIM86615.1 - 1.5e-30 106.0 1.4 3e-30 105.0 1.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EIM86615.1 - 3.7e-16 59.0 30.5 3.7e-16 59.0 21.1 3.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region DUF2722 PF10846.3 EIM86615.1 - 0.12 11.3 3.5 0.16 10.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 EIM86615.1 - 1.1 7.1 25.1 1.4 6.7 17.4 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EIM86615.1 - 1.5 6.8 10.2 2.7 5.9 7.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DEAD PF00270.24 EIM86616.1 - 3.2e-39 134.1 0.3 6e-39 133.2 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM86616.1 - 2.5e-20 72.0 0.0 1.4e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EIM86616.1 - 0.00026 20.8 0.6 0.00051 19.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIM86616.1 - 0.027 13.5 0.8 0.1 11.6 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Apt1 PF10351.4 EIM86616.1 - 1.5 7.5 5.5 2.5 6.8 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NACHT PF05729.7 EIM86617.1 - 4.1e-11 42.8 0.1 1.2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIM86617.1 - 0.0014 18.7 0.2 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM86617.1 - 0.0031 17.2 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EIM86617.1 - 0.0037 17.2 1.5 0.016 15.2 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EIM86617.1 - 0.0047 15.8 0.2 0.026 13.3 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 EIM86617.1 - 0.0054 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.4 EIM86617.1 - 0.012 14.5 0.1 0.03 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EIM86617.1 - 0.021 14.9 0.7 0.48 10.6 0.0 3.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIM86617.1 - 0.023 14.5 0.1 0.39 10.6 0.0 2.9 2 2 0 2 2 2 0 AAA domain KaiC PF06745.8 EIM86617.1 - 0.1 11.7 1.5 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 KaiC Peptidase_S10 PF00450.17 EIM86617.1 - 0.28 10.3 1.4 0.4 9.7 0.2 1.7 1 1 1 2 2 2 0 Serine carboxypeptidase Ank_2 PF12796.2 EIM86618.1 - 0.011 16.0 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EIM86618.1 - 0.057 13.2 0.1 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 EIM86618.1 - 0.067 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 EIM86618.1 - 0.088 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mit_KHE1 PF10173.4 EIM86619.1 - 0.057 13.2 0.4 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Mito_carr PF00153.22 EIM86620.1 - 1.8e-64 213.4 2.2 7.8e-22 76.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.7 EIM86621.1 - 6.3e-31 107.1 0.0 8.4e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EIM86621.1 - 6.6e-21 74.2 0.0 1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MAS20 PF02064.10 EIM86622.1 - 0.03 14.2 0.3 0.036 13.9 0.2 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor DUF1919 PF08942.5 EIM86622.1 - 0.052 12.8 0.3 0.066 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) DUF4500 PF14937.1 EIM86622.1 - 0.086 12.6 0.2 0.23 11.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4500) F-box-like PF12937.2 EIM86623.1 - 9.3e-11 41.2 0.3 2.3e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM86623.1 - 0.00052 19.5 0.1 0.00096 18.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain Baculo_helicase PF04735.7 EIM86623.1 - 5.9 4.1 9.4 8.2 3.6 6.5 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase ERG4_ERG24 PF01222.12 EIM86624.1 - 1.1e-133 445.9 24.2 1.2e-133 445.7 16.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM86624.1 - 7.9e-07 28.6 3.2 1.7e-06 27.5 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIM86624.1 - 0.053 13.7 1.7 0.61 10.3 0.1 2.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3176 PF11374.3 EIM86624.1 - 1 9.2 7.4 4.5 7.1 0.0 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3176) FAD_binding_3 PF01494.14 EIM86625.1 - 5.7e-24 84.8 1.8 6.1e-15 55.1 0.0 2.9 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 EIM86625.1 - 6.5e-08 31.8 0.1 0.00035 19.6 0.0 2.8 4 0 0 4 4 4 2 Lycopene cyclase protein DAO PF01266.19 EIM86625.1 - 2.5e-07 29.9 0.0 0.0037 16.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIM86625.1 - 3.1e-06 26.0 0.1 0.02 13.5 0.1 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.22 EIM86625.1 - 4.2e-05 23.8 0.0 0.074 13.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EIM86625.1 - 4.4e-05 22.4 0.0 6.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EIM86625.1 - 0.00091 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM86625.1 - 0.0016 18.2 0.1 0.0064 16.2 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EIM86625.1 - 0.0023 16.4 0.0 0.042 12.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EIM86625.1 - 0.0096 15.0 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIM86625.1 - 0.021 13.6 1.7 0.17 10.6 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EIM86625.1 - 0.024 14.7 0.1 0.098 12.7 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM86625.1 - 0.038 12.8 0.0 0.095 11.5 0.0 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM86625.1 - 0.042 13.8 0.1 0.042 13.8 0.1 2.2 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain RNA_pol PF00940.14 EIM86625.1 - 0.21 9.9 0.0 0.31 9.4 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase Sec6 PF06046.8 EIM86626.1 - 2.5e-153 511.1 4.9 2.5e-153 511.1 3.4 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF3289 PF11692.3 EIM86626.1 - 0.0041 16.4 0.4 0.064 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3289) HECT PF00632.20 EIM86626.1 - 0.035 13.2 0.1 0.07 12.2 0.1 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Bromo_TP PF07524.8 EIM86626.1 - 0.047 13.4 0.3 19 5.1 0.0 3.9 2 1 1 3 3 3 0 Bromodomain associated PspB PF06667.7 EIM86626.1 - 0.048 13.5 5.1 0.092 12.6 0.3 3.5 3 0 0 3 3 3 0 Phage shock protein B CHAT PF12770.2 EIM86627.1 - 4.2e-33 114.7 0.0 7.3e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM86627.1 - 5.4e-06 26.2 0.2 0.43 10.5 0.0 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM86627.1 - 0.013 16.0 3.4 3.4 8.5 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat CN_hydrolase PF00795.17 EIM86628.1 - 5.1e-29 100.9 0.0 7.6e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EIM86628.1 - 1e-21 76.9 0.0 5.3e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EIM86628.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase An_peroxidase PF03098.10 EIM86629.1 - 4.1e-65 220.1 0.0 2.6e-62 210.8 0.0 3.0 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EIM86629.1 - 0.024 13.1 0.0 0.06 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome P450 Pkinase PF00069.20 EIM86630.1 - 2.3e-66 223.6 0.0 3.1e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86630.1 - 1.6e-51 174.8 0.0 2.3e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIM86630.1 - 1.8e-09 37.1 3.9 3e-09 36.4 2.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 EIM86630.1 - 0.0016 17.5 0.0 0.067 12.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIM86630.1 - 0.021 14.1 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PHD PF00628.24 EIM86630.1 - 0.035 13.7 4.6 0.07 12.8 3.2 1.5 1 0 0 1 1 1 0 PHD-finger RIO1 PF01163.17 EIM86630.1 - 0.038 13.3 0.1 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 EIM86630.1 - 0.039 12.7 0.1 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EF-hand_8 PF13833.1 EIM86630.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Prok-RING_1 PF14446.1 EIM86630.1 - 0.41 10.4 8.2 0.052 13.2 2.7 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Tnp_zf-ribbon_2 PF13842.1 EIM86630.1 - 0.8 10.1 7.0 1.6 9.2 4.9 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Peptidase_C14 PF00656.17 EIM86632.1 - 1.7e-21 77.0 0.0 4.2e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIM86633.1 - 1.4e-12 47.8 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain MT PF12777.2 EIM86633.1 - 0.26 9.9 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor TFIIS_M PF07500.9 EIM86634.1 - 1.1e-16 60.8 1.4 1.1e-16 60.8 1.0 2.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EIM86634.1 - 1.4e-08 34.3 11.2 2.4e-08 33.5 7.8 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 EIM86634.1 - 3e-07 30.9 0.0 6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.1 EIM86634.1 - 0.54 9.6 6.7 0.9 8.9 4.6 1.4 1 0 0 1 1 1 0 PHD-finger FUSC-like PF12805.2 EIM86634.1 - 1.9 7.3 4.6 3 6.6 3.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS MRP-S27 PF10037.4 EIM86634.1 - 6.2 5.6 10.0 11 4.7 6.9 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PKD_channel PF08016.7 EIM86635.1 - 0.02 13.3 10.7 0.17 10.2 0.2 2.4 2 0 0 2 2 2 0 Polycystin cation channel Ank_2 PF12796.2 EIM86636.1 - 1.3e-13 51.1 0.1 2.7e-08 34.0 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM86636.1 - 1.5e-13 49.7 1.2 3.9e-06 26.3 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIM86636.1 - 1.1e-11 44.9 0.1 2.5e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM86636.1 - 3.8e-10 39.6 0.3 0.00018 21.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM86636.1 - 4e-09 35.8 0.2 0.0039 17.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 EIM86636.1 - 0.00078 19.0 0.2 0.0092 15.5 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain DUF3562 PF12085.3 EIM86636.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Phage_GP20 PF06810.6 EIM86636.1 - 0.18 11.2 0.9 0.33 10.3 0.6 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 PMT PF02366.13 EIM86638.1 - 1.1e-78 263.9 15.8 1.1e-78 263.9 10.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIM86638.1 - 2.1e-15 56.7 2.5 4.2e-15 55.7 0.9 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EIM86638.1 - 1.9e-06 27.8 11.6 1.9e-06 27.8 8.0 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 EIM86639.1 - 2e-50 166.9 8.0 5.6e-10 38.7 0.1 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EIM86639.1 - 8.1e-13 47.3 1.1 1.7e-12 46.3 0.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EIM86639.1 - 2.4e-05 23.5 0.2 0.73 8.8 0.0 3.4 1 1 1 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EIM86639.1 - 0.26 9.3 4.2 3.1 5.7 0.1 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PX PF00787.19 EIM86640.1 - 5.3e-17 61.6 0.0 1.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Glyco_hydro_61 PF03443.9 EIM86641.1 - 4.5e-59 199.8 0.0 5.2e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DWNN PF08783.6 EIM86642.1 - 8.5e-30 102.5 0.6 8.5e-30 102.5 0.4 2.0 3 0 0 3 3 3 1 DWNN domain zf-CCHC_2 PF13696.1 EIM86642.1 - 4.6e-08 32.4 1.7 1.4e-07 30.8 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIM86642.1 - 1e-05 25.1 2.0 2.3e-05 24.0 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EIM86642.1 - 0.011 15.7 10.7 0.011 15.7 7.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0560 PF10577.4 EIM86642.1 - 0.17 10.0 10.4 0.27 9.4 7.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 zf-CCHC_5 PF14787.1 EIM86642.1 - 0.72 9.3 5.8 0.77 9.2 2.0 2.4 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger DUF2229 PF09989.4 EIM86642.1 - 1.1 8.6 3.7 3.1 7.1 2.5 1.7 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-C3HC4_3 PF13920.1 EIM86642.1 - 4.7 6.9 12.8 0.41 10.3 4.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM86642.1 - 7.4 6.4 15.3 0.16 11.8 5.9 1.8 2 0 0 2 2 2 0 Ring finger domain Vps5 PF09325.5 EIM86643.1 - 5.6e-60 202.5 5.7 2.9e-58 196.9 4.0 2.1 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIM86643.1 - 2.8e-23 81.8 0.0 1.3e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EIM86643.1 - 0.0014 17.9 0.4 0.035 13.3 0.1 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein TPT PF03151.11 EIM86645.1 - 2.8e-32 111.5 8.1 2.8e-32 111.5 5.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIM86645.1 - 3.5e-14 52.4 17.5 4.6e-14 52.0 12.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIM86645.1 - 1.8e-10 40.9 25.2 1.4e-08 34.8 3.5 3.0 2 1 1 3 3 3 2 EamA-like transporter family HAMP PF00672.20 EIM86646.1 - 2.3e-49 165.4 22.0 4.9e-08 33.0 0.1 8.1 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 EIM86646.1 - 8.7e-28 96.2 1.4 4.2e-26 90.8 0.0 3.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM86646.1 - 2.1e-23 82.4 0.5 8.1e-23 80.5 0.4 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EIM86646.1 - 3.3e-17 62.2 1.0 3.3e-17 62.2 0.7 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Histone PF00125.19 EIM86646.1 - 0.027 14.6 0.6 1.8 8.7 0.1 3.6 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 DUF2365 PF10157.4 EIM86646.1 - 3.1 7.6 23.2 12 5.7 0.1 7.3 7 3 1 8 8 8 0 Uncharacterized conserved protein (DUF2365) AcylCoA_dehyd_C PF12186.3 EIM86646.1 - 4.3 7.2 14.6 18 5.2 0.0 6.7 8 1 0 8 8 8 0 Acyl-CoA dehydrogenase C terminal NAAA-beta PF15508.1 EIM86646.1 - 8.5 6.8 6.5 21 5.5 0.1 4.7 7 0 0 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase RTA1 PF04479.8 EIM86649.1 - 2.2e-35 122.1 2.3 3.3e-35 121.6 1.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.13 EIM86650.1 - 8.9e-27 93.5 0.8 1.9e-26 92.5 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86650.1 - 1.7e-09 37.4 10.8 3e-09 36.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1604 PF07713.8 EIM86651.1 - 2.4e-37 126.5 1.2 2.4e-37 126.5 0.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EIM86651.1 - 7.6e-06 25.6 1.8 2.2e-05 24.1 0.2 2.7 2 0 0 2 2 2 1 G-patch domain WD40 PF00400.27 EIM86652.1 - 3e-20 71.2 13.4 7.7e-08 31.9 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Lactonase PF10282.4 EIM86652.1 - 0.00021 20.5 0.0 0.36 9.8 0.0 2.6 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Apc4_WD40 PF12894.2 EIM86652.1 - 0.028 13.9 0.7 0.056 12.9 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EIM86652.1 - 0.034 12.8 0.1 0.17 10.6 0.1 2.0 3 0 0 3 3 3 0 Nup133 N terminal like DUF2408 PF10303.4 EIM86653.1 - 9.2e-58 194.1 0.5 5.6e-31 107.4 0.0 5.2 3 2 2 5 5 5 5 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 EIM86653.1 - 0.026 14.8 9.1 0.98 9.7 0.1 5.1 6 0 0 6 6 6 0 Snapin/Pallidin DUF2968 PF11180.3 EIM86653.1 - 0.14 11.4 1.1 0.33 10.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) CK2S PF15011.1 EIM86653.1 - 0.14 11.8 3.8 3.2 7.4 0.2 3.4 3 0 0 3 3 3 0 Casein Kinase 2 substrate FUSC PF04632.7 EIM86653.1 - 0.26 9.6 0.6 0.37 9.1 0.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MscS_porin PF12795.2 EIM86653.1 - 2.7 7.2 7.2 3.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Nucleoplasmin PF03066.10 EIM86653.1 - 3.3 7.2 8.7 6.2 6.3 6.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Tropomyosin_1 PF12718.2 EIM86654.1 - 3.9e-44 149.9 35.9 4.7e-44 149.6 24.9 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EIM86654.1 - 6.7e-11 41.7 35.8 2.9e-05 23.2 8.2 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 EIM86654.1 - 0.01 15.6 37.1 0.14 11.9 7.2 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EIM86654.1 - 0.012 14.1 34.9 0.0093 14.4 17.3 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light GAS PF13851.1 EIM86654.1 - 0.014 14.6 35.0 0.016 14.4 24.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 EIM86654.1 - 0.055 12.8 30.6 0.012 15.1 14.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.3 EIM86654.1 - 0.066 12.4 24.7 0.12 11.5 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TAFH PF07531.9 EIM86654.1 - 0.11 12.1 4.3 0.074 12.7 1.4 1.9 1 1 1 2 2 2 0 NHR1 homology to TAF Flagellin_C PF00700.16 EIM86654.1 - 0.11 12.7 4.9 0.92 9.7 0.3 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region AAA_13 PF13166.1 EIM86654.1 - 0.37 9.2 20.8 0.48 8.8 14.4 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EIM86654.1 - 0.57 7.4 30.0 0.68 7.1 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EIM86654.1 - 0.59 9.0 24.7 0.46 9.3 15.7 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EIM86654.1 - 0.94 9.4 35.9 1.2 9.1 7.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EIM86654.1 - 1.5 7.8 36.0 0.27 10.2 15.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EIM86654.1 - 1.9 6.2 17.2 2.2 6.0 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_4 PF07993.7 EIM86654.1 - 2.1 7.1 10.4 0.49 9.2 0.7 2.2 1 1 0 2 2 2 0 Male sterility protein DUF1664 PF07889.7 EIM86654.1 - 2.4 7.9 16.5 1 9.1 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.11 EIM86654.1 - 3.7 7.6 33.8 7.6 6.6 10.4 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein ADIP PF11559.3 EIM86654.1 - 4.2 7.2 32.4 7.9 6.3 3.2 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GLE1 PF07817.8 EIM86654.1 - 4.5 6.1 9.7 0.44 9.4 2.7 1.9 1 1 1 2 2 2 0 GLE1-like protein Laminin_II PF06009.7 EIM86654.1 - 4.5 7.0 17.8 3.6 7.3 4.5 2.3 1 1 2 3 3 3 0 Laminin Domain II DUF641 PF04859.7 EIM86654.1 - 5.1 6.8 20.4 4.8 6.9 2.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.14 EIM86654.1 - 5.6 6.4 36.8 1.7 8.1 22.7 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HrpF PF06266.7 EIM86654.1 - 5.8 7.1 7.1 6 7.0 0.2 3.4 2 1 1 3 3 3 0 HrpF protein Fib_alpha PF08702.5 EIM86654.1 - 6.6 6.8 16.6 3.5 7.7 4.1 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HisKA_3 PF07730.8 EIM86654.1 - 6.6 7.1 15.9 3.2 8.1 2.9 3.8 1 1 2 3 3 3 0 Histidine kinase IncA PF04156.9 EIM86654.1 - 7.1 6.1 33.2 56 3.2 23.0 2.1 1 1 0 1 1 1 0 IncA protein Asp PF00026.18 EIM86655.1 - 1.2e-25 90.4 8.0 1.2e-25 90.4 5.6 2.6 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM86655.1 - 0.0018 18.7 1.0 0.015 15.8 0.0 2.9 2 1 1 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EIM86655.1 - 0.0037 16.8 0.1 0.097 12.2 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIM86655.1 - 0.6 10.0 4.3 2.2 8.1 0.6 2.8 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Ank_2 PF12796.2 EIM86656.1 - 1.8e-26 92.3 0.0 4.8e-12 46.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIM86656.1 - 1.4e-22 78.2 0.4 9.8e-05 21.9 0.0 5.5 5 0 0 5 5 4 4 Ankyrin repeat Ank_3 PF13606.1 EIM86656.1 - 4.2e-20 69.8 0.2 0.001 19.0 0.0 6.3 7 0 0 7 7 5 4 Ankyrin repeat Ank_4 PF13637.1 EIM86656.1 - 4e-17 62.2 0.1 1.6e-06 28.4 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM86656.1 - 1.7e-15 56.6 0.3 0.00017 21.7 0.0 4.9 3 1 0 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 EIM86656.1 - 1.3e-11 44.8 0.6 1.1e-10 41.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EIM86656.1 - 1.8e-08 34.2 0.0 1.4e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EIM86656.1 - 5.2e-05 23.3 0.0 0.0006 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EIM86656.1 - 0.00045 19.3 0.0 0.037 13.0 0.0 2.3 1 1 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 EIM86656.1 - 0.00051 18.9 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EIM86656.1 - 0.012 15.5 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIM86656.1 - 0.026 14.2 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EIM86656.1 - 0.031 14.1 0.1 0.98 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 EIM86656.1 - 0.045 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF1199 PF06712.6 EIM86656.1 - 0.11 12.3 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Tim44 PF04280.10 EIM86657.1 - 1e-30 106.6 0.4 1e-30 106.6 0.3 1.8 2 0 0 2 2 2 1 Tim44-like domain Sigma54_CBD PF04963.8 EIM86657.1 - 0.023 14.1 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain T2SF PF00482.18 EIM86657.1 - 0.26 11.2 2.7 0.54 10.1 0.8 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DMPK_coil PF08826.5 EIM86657.1 - 0.35 10.7 5.6 0.089 12.7 0.4 2.6 2 1 1 3 3 3 0 DMPK coiled coil domain like SOBP PF15279.1 EIM86657.1 - 7.2 6.9 7.3 0.57 10.5 0.6 1.8 1 1 1 2 2 2 0 Sine oculis-binding protein EMP24_GP25L PF01105.19 EIM86658.1 - 3e-48 163.9 0.1 3.4e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAP_RNA-bind PF04926.10 EIM86658.1 - 0.065 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain DUF1395 PF07160.7 EIM86658.1 - 0.17 11.3 2.9 0.26 10.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Brix PF04427.13 EIM86659.1 - 1.3e-41 142.3 0.0 1.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain ADH_zinc_N PF00107.21 EIM86660.1 - 1.4e-13 50.5 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM86660.1 - 0.1 12.3 0.1 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF1295 PF06966.7 EIM86661.1 - 1.9e-34 119.0 4.4 6.3e-33 114.0 3.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) GHL15 PF14885.1 EIM86661.1 - 0.11 12.7 1.9 0.23 11.6 1.3 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Asp PF00026.18 EIM86662.1 - 5.4e-29 101.4 2.5 6.7e-28 97.8 1.7 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM86662.1 - 8.8e-06 26.1 0.4 0.0088 16.5 0.0 3.9 3 1 1 4 4 4 1 Aspartyl protease RVP PF00077.15 EIM86662.1 - 0.011 15.6 0.0 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIM86662.1 - 0.019 14.7 0.6 6 6.7 0.1 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 EIM86662.1 - 0.057 13.3 2.8 2 8.3 0.4 3.1 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Terpene_synth_C PF03936.11 EIM86663.1 - 1.1e-08 34.7 0.3 1.8e-08 33.9 0.2 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Asp PF00026.18 EIM86664.1 - 3.8e-24 85.5 1.7 4.1e-22 78.8 1.2 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM86664.1 - 0.0098 16.3 1.0 0.15 12.5 0.1 3.1 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.15 EIM86664.1 - 0.099 12.5 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease ATP-synt_ab PF00006.20 EIM86665.1 - 4.5e-71 238.7 0.0 6.9e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIM86665.1 - 2.2e-23 82.8 0.1 6.2e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIM86665.1 - 8.3e-18 64.3 1.2 2.4e-17 62.8 0.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.16 EIM86666.1 - 8.6e-16 57.8 0.1 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FF PF01846.14 EIM86667.1 - 5.1e-28 96.7 6.5 5.1e-10 39.1 0.0 6.3 6 0 0 6 6 6 4 FF domain WW PF00397.21 EIM86667.1 - 8.3e-14 51.1 17.2 7.6e-08 32.0 2.8 2.8 2 0 0 2 2 2 2 WW domain TarH PF02203.10 EIM86667.1 - 0.29 10.9 4.1 0.11 12.3 0.3 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue Voltage_CLC PF00654.15 EIM86669.1 - 2.2e-85 286.8 28.8 2.2e-85 286.8 20.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel DUF543 PF04418.7 EIM86669.1 - 2 8.4 4.9 11 6.0 3.4 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) GMC_oxred_N PF00732.14 EIM86670.1 - 2.7e-45 154.7 0.1 1e-26 93.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM86670.1 - 2e-34 118.9 0.0 3.6e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM86670.1 - 2.3e-05 23.4 0.1 0.0003 19.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM86670.1 - 2.4e-05 24.2 1.1 4.6e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM86670.1 - 0.00043 19.3 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM86670.1 - 0.00081 18.3 0.5 0.0013 17.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM86670.1 - 0.002 18.0 0.1 0.0073 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM86670.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM86670.1 - 0.021 14.6 0.0 0.098 12.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIM86670.1 - 0.028 12.9 0.5 0.14 10.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EIM86670.1 - 0.069 11.7 0.3 0.68 8.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Terpene_synth_C PF03936.11 EIM86671.1 - 2e-06 27.2 0.2 3.8e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1814 PF08843.6 EIM86674.1 - 0.0006 19.6 0.0 0.00097 18.9 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Metallophos_2 PF12850.2 EIM86675.1 - 2.7e-06 27.2 0.0 5.8e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIM86675.1 - 9.1e-06 25.2 0.1 2.9e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cyto_heme_lyase PF01265.12 EIM86676.1 - 2.8e-63 213.9 0.1 3.2e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3778 PF12620.3 EIM86676.1 - 0.18 11.3 0.4 0.67 9.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3778) Rifin_STEVOR PF02009.11 EIM86679.1 - 0.0013 18.4 4.8 0.003 17.2 3.4 1.5 1 1 0 1 1 1 1 Rifin/stevor family stn_TNFRSF12A PF12191.3 EIM86679.1 - 0.012 15.6 0.3 0.026 14.5 0.1 1.6 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Syndecan PF01034.15 EIM86679.1 - 0.039 13.6 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EIM86679.1 - 0.051 13.9 0.4 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EIM86679.1 - 0.085 12.1 1.3 0.27 10.5 0.9 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF809 PF05663.6 EIM86679.1 - 0.43 10.4 1.1 0.97 9.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF1469 PF07332.6 EIM86679.1 - 1.7 8.3 9.1 0.074 12.7 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) FMN_dh PF01070.13 EIM86680.1 - 3.8e-104 348.3 0.0 5e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EIM86680.1 - 1.1e-05 24.5 0.1 1.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EIM86680.1 - 0.0001 21.4 0.9 0.03 13.3 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EIM86680.1 - 0.00012 21.3 0.3 0.00018 20.7 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 EIM86680.1 - 0.00013 21.0 0.6 0.00024 20.1 0.1 1.6 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 EIM86680.1 - 0.00016 20.7 1.4 0.00022 20.2 0.4 1.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EIM86680.1 - 0.0039 16.4 0.4 0.077 12.2 0.1 2.5 1 1 2 3 3 3 1 Histidine biosynthesis protein PcrB PF01884.12 EIM86680.1 - 0.03 13.5 1.3 4.6 6.4 0.4 2.3 1 1 1 2 2 2 0 PcrB family zf-MYND PF01753.13 EIM86681.1 - 3.9e-11 42.6 10.0 1.3e-10 40.9 6.9 1.9 1 0 0 1 1 1 1 MYND finger Glyco_hydro_18 PF00704.23 EIM86682.1 - 8.4e-63 212.8 2.9 1.2e-62 212.4 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Oxidored_FMN PF00724.15 EIM86683.1 - 6.1e-84 281.9 0.0 6.9e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HMG_box_2 PF09011.5 EIM86684.1 - 0.0004 20.7 0.3 0.025 14.9 0.0 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EIM86684.1 - 0.02 15.1 1.0 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box His_Phos_2 PF00328.17 EIM86685.1 - 0.0076 15.6 0.0 0.11 11.8 0.0 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Filament PF00038.16 EIM86687.1 - 0.012 15.0 0.5 0.012 15.0 0.3 1.6 2 0 0 2 2 2 0 Intermediate filament protein DUF3498 PF12004.3 EIM86687.1 - 0.044 12.9 6.2 0.026 13.6 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) DUF3287 PF11690.3 EIM86687.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF972 PF06156.8 EIM86687.1 - 0.44 10.9 3.9 0.36 11.2 1.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIM86687.1 - 4.5 6.8 6.5 2.9 7.4 3.0 1.7 1 1 1 2 2 2 0 IncA protein Peptidase_M20 PF01546.23 EIM86689.1 - 8e-25 87.4 0.1 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM86689.1 - 4.1e-09 36.1 0.0 8.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM86689.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF908 PF06012.7 EIM86689.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Peptidase_M20 PF01546.23 EIM86690.1 - 2.1e-18 66.5 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM86690.1 - 1.5e-09 37.5 0.0 6.1e-09 35.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain zf-H2C2_2 PF13465.1 EIM86691.1 - 1.1e-25 88.5 42.6 7.5e-07 29.1 0.2 7.9 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2 PF00096.21 EIM86691.1 - 1.4e-24 84.8 52.0 1.4e-06 28.2 0.1 8.6 8 1 1 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM86691.1 - 1.9e-12 46.5 43.3 0.0019 18.3 0.1 8.0 7 1 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIM86691.1 - 6.6e-09 35.6 5.2 0.0032 17.5 0.4 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EIM86691.1 - 9.8e-05 21.9 7.7 0.13 11.9 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EIM86691.1 - 0.00078 19.2 5.3 0.005 16.6 0.3 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIM86691.1 - 0.00079 19.5 27.0 0.31 11.1 3.8 5.3 3 2 2 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EIM86691.1 - 0.041 14.0 28.0 0.55 10.4 1.1 5.7 4 3 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIM86691.1 - 0.056 13.6 1.3 0.056 13.6 0.9 7.3 7 0 0 7 7 7 0 C2H2-type zinc-finger domain zf-met PF12874.2 EIM86691.1 - 0.12 12.6 0.5 0.12 12.6 0.4 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DNA_pol_E_B PF04042.11 EIM86693.1 - 4.4e-39 133.9 0.1 7.5e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fork_head PF00250.13 EIM86694.1 - 2.5e-20 72.2 0.0 7.4e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Fork head domain BTB PF00651.26 EIM86695.1 - 3.3e-10 39.9 0.0 0.0009 19.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DZR PF12773.2 EIM86695.1 - 0.033 14.0 3.2 9.3 6.1 0.0 3.8 4 0 0 4 4 4 0 Double zinc ribbon Zeta_toxin PF06414.7 EIM86695.1 - 0.16 11.0 0.1 18 4.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Adaptin_N PF01602.15 EIM86696.1 - 7.7e-141 469.9 8.8 8.9e-141 469.7 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EIM86696.1 - 7.1e-21 74.6 1.8 8.4e-21 74.4 0.2 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EIM86696.1 - 2.3e-05 24.6 3.7 0.22 11.8 0.0 4.8 3 3 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EIM86696.1 - 0.00026 20.8 0.7 12 6.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EIM86696.1 - 0.00034 20.5 4.0 0.034 14.0 0.5 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EIM86696.1 - 0.0053 16.3 0.4 0.023 14.2 0.2 2.1 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) RIX1 PF08167.7 EIM86696.1 - 0.0078 15.8 0.2 0.46 10.1 0.0 3.4 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis NPCBM_assoc PF10633.4 EIM86696.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Arm PF00514.18 EIM86696.1 - 0.11 12.3 0.5 96 3.0 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SF3b1 PF08920.5 EIM86697.1 - 9.5e-25 87.3 7.5 1.1e-23 83.8 4.3 2.8 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.17 EIM86697.1 - 1.4e-11 43.4 7.7 0.026 14.6 0.0 9.8 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.1 EIM86697.1 - 2.3e-11 43.7 11.9 0.0001 22.5 0.0 7.3 6 2 3 9 9 9 3 HEAT repeats HEAT_EZ PF13513.1 EIM86697.1 - 8.7e-11 41.9 3.8 0.047 14.1 0.0 8.7 7 2 2 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIM86697.1 - 5.4e-07 29.9 1.1 0.67 10.3 0.0 5.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIM86697.1 - 1.3e-05 23.7 0.1 0.057 11.7 0.0 3.3 1 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EIM86697.1 - 0.0004 19.7 0.7 7.5 5.8 0.0 4.7 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 EIM86697.1 - 0.0018 17.6 1.6 3.4 6.9 0.0 3.8 3 1 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.2 EIM86697.1 - 0.057 13.2 5.1 41 3.9 0.0 5.1 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIM86697.1 - 0.094 12.5 0.3 9.7 6.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Helicase_C PF00271.26 EIM86698.1 - 4.5e-22 77.7 0.2 1.2e-19 69.9 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Alpha_kinase PF02816.13 EIM86701.1 - 1.9e-17 63.5 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family DNA_ligase_A_M PF01068.16 EIM86702.1 - 2.3e-52 177.3 0.0 4.2e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIM86702.1 - 4.2e-40 137.4 0.0 7.7e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIM86702.1 - 6.7e-13 48.8 0.0 2.1e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EIM86702.1 - 1.9e-09 37.5 0.1 0.0012 18.9 0.0 3.1 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIM86702.1 - 0.00085 19.1 0.0 0.44 10.4 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain RhoGAP PF00620.22 EIM86703.1 - 2.2e-36 124.7 0.0 4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EIM86703.1 - 1.3e-27 95.5 39.0 5.8e-11 42.2 4.8 4.6 4 0 0 4 4 4 4 LIM domain Zip PF02535.17 EIM86703.1 - 0.24 10.3 1.8 0.26 10.2 0.3 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter APH PF01636.18 EIM86704.1 - 1.9e-05 24.5 2.3 4e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM86704.1 - 2.1e-05 23.8 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86704.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ribosomal_S19 PF00203.16 EIM86705.1 - 8.3e-34 115.0 0.3 1.3e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EIM86705.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH Ribosomal_60s PF00428.14 EIM86706.1 - 7.8e-30 103.1 14.7 8.9e-30 102.9 10.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fungal_trans PF04082.13 EIM86707.1 - 1.1e-10 40.8 0.5 2.1e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86707.1 - 5.7e-10 38.9 10.0 1e-09 38.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EIM86708.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM86708.1 - 0.0013 17.8 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86708.1 - 0.046 12.7 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase ParA PF10609.4 EIM86710.1 - 4.1e-37 125.9 0.0 8.6e-37 124.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIM86710.1 - 8.2e-14 51.4 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EIM86710.1 - 2.2e-05 23.6 0.2 0.0032 16.5 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EIM86710.1 - 0.0004 19.8 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIM86710.1 - 0.0012 18.1 0.0 1.2 8.1 0.0 2.5 2 1 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 EIM86710.1 - 0.0022 17.9 0.0 0.007 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EIM86710.1 - 0.0083 15.7 0.0 0.061 12.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIM86710.1 - 0.015 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 EIM86710.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein YjeF_N PF03853.10 EIM86710.1 - 0.068 12.7 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus AAA_29 PF13555.1 EIM86710.1 - 0.11 12.0 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain VirE PF05272.6 EIM86710.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E NB-ARC PF00931.17 EIM86710.1 - 0.19 10.5 0.1 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain DnaJ PF00226.26 EIM86711.1 - 4.2e-12 45.6 4.2 1.5e-11 43.8 0.1 3.0 3 0 0 3 3 3 1 DnaJ domain CAF-1_p150 PF11600.3 EIM86711.1 - 3.2 7.0 27.6 0.088 12.1 14.3 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 EIM86712.1 - 1.1e-71 241.0 0.0 1.7e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86712.1 - 1e-34 119.7 0.0 1.5e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM86712.1 - 0.003 16.5 0.0 0.0075 15.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM86712.1 - 0.041 13.6 2.0 0.12 12.1 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM86712.1 - 0.086 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM86712.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Symplekin_C PF12295.3 EIM86713.1 - 4.3e-58 196.2 0.4 1.3e-57 194.7 0.3 1.8 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EIM86713.1 - 1.1e-49 168.9 0.0 2.2e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.1 EIM86713.1 - 0.00023 21.3 0.2 1.5 9.1 0.0 4.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EIM86713.1 - 0.024 14.6 2.2 40 4.6 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat V-ATPase_G PF03179.10 EIM86714.1 - 1.3e-34 118.5 14.0 1.6e-34 118.3 9.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF4456 PF14644.1 EIM86714.1 - 0.011 14.9 5.0 0.015 14.4 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Picorna_P3A PF06363.6 EIM86714.1 - 0.031 14.2 0.2 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Picornaviridae P3A protein DXP_synthase_N PF13292.1 EIM86714.1 - 0.041 12.7 0.1 0.05 12.5 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TraC_F_IV PF11130.3 EIM86714.1 - 0.07 12.5 0.4 0.099 12.0 0.3 1.3 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer DUF2362 PF10154.4 EIM86714.1 - 0.08 11.6 2.8 0.096 11.3 1.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Nop25 PF09805.4 EIM86714.1 - 0.18 11.8 10.8 0.24 11.4 7.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ATP-synt_B PF00430.13 EIM86714.1 - 0.21 11.3 17.0 0.15 11.8 7.6 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.17 EIM86714.1 - 0.58 10.1 9.5 0.74 9.8 5.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RRF PF01765.14 EIM86714.1 - 1.2 8.6 8.1 1.5 8.2 5.4 1.4 1 1 0 1 1 1 0 Ribosome recycling factor PGBA_C PF15437.1 EIM86714.1 - 5.2 7.2 12.6 0.68 10.0 5.5 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DUF2390 PF09523.5 EIM86714.1 - 5.3 7.2 8.0 2 8.6 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) Pup PF05639.6 EIM86714.1 - 5.6 7.5 7.2 13 6.3 5.0 1.8 1 1 0 1 1 1 0 Pup-like protein HrpE PF06188.7 EIM86714.1 - 8.4 6.0 10.1 26 4.5 6.8 1.7 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TPR_10 PF13374.1 EIM86715.1 - 3e-25 87.3 7.8 9.7e-09 34.8 0.1 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIM86715.1 - 5.5e-25 87.1 16.4 4.6e-08 32.8 0.8 4.3 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIM86715.1 - 8.1e-08 31.6 9.6 0.097 12.6 0.4 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIM86715.1 - 2.5e-07 30.4 4.8 0.29 11.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86715.1 - 4.3e-07 29.4 2.0 0.059 13.0 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EIM86715.1 - 7.6e-07 29.6 2.5 1.9 9.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86715.1 - 2.1e-06 27.9 5.8 0.031 14.6 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM86715.1 - 6.8e-05 23.1 6.9 2.6 8.9 0.1 5.2 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM86715.1 - 0.00018 21.0 4.3 0.31 10.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86715.1 - 0.0002 20.7 3.9 2.2 8.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM86715.1 - 0.00026 21.0 1.3 0.65 10.1 0.0 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EIM86715.1 - 0.0013 18.7 6.9 1.4 9.0 0.2 4.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM86715.1 - 0.0051 17.1 8.5 1.5 9.4 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIM86715.1 - 0.013 14.5 0.3 0.14 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM86715.1 - 0.016 15.0 0.4 6.2 6.7 0.0 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EIM86715.1 - 0.044 13.9 2.9 8.6 6.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EIM86715.1 - 0.046 13.7 0.7 18 5.5 0.1 3.4 3 0 0 3 3 3 0 PPR repeat TPR_7 PF13176.1 EIM86715.1 - 0.15 11.9 2.0 1.3 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM86717.1 - 2.1e-23 81.9 0.5 3.5e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EIM86717.1 - 8.7e-16 56.9 0.0 1.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EIM86717.1 - 0.00051 19.7 0.4 0.00051 19.7 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM86717.1 - 0.0017 18.9 0.1 0.0051 17.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM86717.1 - 0.007 15.9 0.5 0.02 14.5 0.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM86717.1 - 0.0084 16.4 0.7 0.018 15.3 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EIM86717.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIM86717.1 - 0.046 14.1 0.1 0.21 12.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM86717.1 - 0.057 13.0 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_10 PF13374.1 EIM86717.1 - 0.21 11.5 1.8 0.24 11.3 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NmrA PF05368.8 EIM86718.1 - 3.2e-26 92.0 0.0 4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM86718.1 - 5.4e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EIM86718.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain SAM_PNT PF02198.11 EIM86718.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Shikimate_DH PF01488.15 EIM86718.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIM86718.1 - 0.13 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EIM86719.1 - 2.2e-07 30.3 0.1 0.013 14.8 0.0 2.4 1 1 1 2 2 2 2 NmrA-like family F420_oxidored PF03807.12 EIM86719.1 - 0.0028 18.0 0.1 0.045 14.1 0.0 2.6 1 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EIM86719.1 - 0.017 15.1 2.0 1 9.3 1.4 2.4 1 1 0 1 1 1 0 NADH(P)-binding Rabaptin PF03528.10 EIM86719.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Rabaptin GFO_IDH_MocA PF01408.17 EIM86719.1 - 0.057 13.9 0.0 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DRMBL PF07522.9 EIM86720.1 - 8.9e-28 96.5 0.0 1.9e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIM86720.1 - 3e-10 39.9 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM86720.1 - 0.029 14.0 0.5 0.058 13.0 0.3 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily WD40 PF00400.27 EIM86721.1 - 8.9e-12 44.4 12.0 5.8e-05 22.8 0.4 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DnaJ PF00226.26 EIM86722.1 - 1.1e-23 82.6 3.2 2e-23 81.9 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain Spore_YtfJ PF09579.5 EIM86722.1 - 1.7 8.5 5.1 5.5 6.9 3.5 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) hDGE_amylase PF14701.1 EIM86724.1 - 1.2e-149 498.8 0.0 1.6e-149 498.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EIM86724.1 - 6.9e-113 377.1 0.0 9.8e-113 376.6 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EIM86724.1 - 2.2e-76 256.5 0.0 3e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EIM86724.1 - 1.7e-18 66.1 0.0 3.7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EIM86724.1 - 0.035 13.5 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain PAT1 PF09770.4 EIM86725.1 - 1.6e-142 476.5 87.0 1.6e-126 423.6 13.1 2.7 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 NmrA PF05368.8 EIM86726.1 - 1.4e-28 99.7 0.0 1.7e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM86726.1 - 3.7e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM86726.1 - 7.1e-08 31.8 0.1 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EIM86726.1 - 3.8e-05 22.5 0.1 5.2e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EIM86726.1 - 5.5e-05 23.2 0.1 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIM86726.1 - 0.00085 19.3 0.1 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EIM86726.1 - 0.0037 16.7 0.1 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 EIM86726.1 - 0.0094 15.4 0.0 0.038 13.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ThiF PF00899.16 EIM86726.1 - 0.013 15.3 1.7 0.093 12.5 0.3 2.4 2 1 1 3 3 3 0 ThiF family KR PF08659.5 EIM86726.1 - 0.018 14.7 0.3 0.046 13.3 0.1 1.8 2 0 0 2 2 2 0 KR domain OCD_Mu_crystall PF02423.10 EIM86726.1 - 0.038 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EIM86726.1 - 0.04 14.3 0.4 0.082 13.3 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SBP_bac_11 PF13531.1 EIM86726.1 - 0.046 13.3 0.3 0.21 11.2 0.0 2.0 2 1 1 3 3 3 0 Bacterial extracellular solute-binding protein NAD_binding_3 PF03447.11 EIM86726.1 - 0.047 14.0 0.1 0.51 10.7 0.0 2.3 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF1697 PF08002.6 EIM86726.1 - 0.049 13.6 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Mito_carr PF00153.22 EIM86728.1 - 4.7e-72 237.7 3.9 3.6e-24 84.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KduI PF04962.7 EIM86728.1 - 0.038 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 KduI/IolB family Pribosyltran PF00156.22 EIM86729.1 - 0.00022 20.9 0.0 0.00079 19.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain RNA_pol_Rpc4 PF05132.9 EIM86730.1 - 4.8e-24 84.8 2.0 1.9e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 API5 PF05918.6 EIM86730.1 - 0.55 8.6 2.6 0.83 8.0 1.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fungal_trans PF04082.13 EIM86731.1 - 1.2e-23 83.3 2.0 2.1e-23 82.5 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM86731.1 - 3.2e-06 26.9 10.5 7.5e-06 25.7 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF849 PF05853.7 EIM86731.1 - 0.049 12.5 0.1 0.099 11.5 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) F-box-like PF12937.2 EIM86732.1 - 0.00089 18.9 0.2 0.0024 17.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like TFIID_30kDa PF03540.8 EIM86733.1 - 7.5e-28 96.1 0.2 1.1e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EIM86733.1 - 0.00096 18.8 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 Bromodomain associated Birna_VP4 PF01768.11 EIM86733.1 - 0.046 12.7 0.2 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein CBFD_NFYB_HMF PF00808.18 EIM86733.1 - 0.13 12.2 0.1 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GFO_IDH_MocA PF01408.17 EIM86734.1 - 1.4e-19 70.8 0.2 2e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_3 PF07859.8 EIM86735.1 - 1.1e-46 159.1 0.0 1.5e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM86735.1 - 8.6e-07 28.0 0.0 2.9e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 EIM86735.1 - 0.033 12.8 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) SAGA-Tad1 PF12767.2 EIM86736.1 - 3.9e-34 118.4 0.0 5.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EIM86736.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCCH PF00642.19 EIM86737.1 - 3.7e-05 23.3 4.5 3.7e-05 23.3 3.1 4.2 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EIM86737.1 - 5.1e-05 23.0 1.7 0.00047 19.9 1.2 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM86737.1 - 5.8e-05 22.6 0.2 0.00019 20.9 0.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM86737.1 - 0.00056 19.5 5.6 0.005 16.5 3.9 2.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM86737.1 - 0.0038 17.2 5.8 0.015 15.3 0.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM86737.1 - 0.0093 15.6 6.0 0.014 15.0 0.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Gemini_coat PF00844.13 EIM86740.1 - 0.043 13.0 0.1 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family Radical_SAM_N PF08497.5 EIM86743.1 - 0.046 12.6 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal DUF3386 PF11866.3 EIM86743.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) SKN1 PF03935.10 EIM86744.1 - 8.1e-204 677.4 5.9 9e-204 677.2 4.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FAD_binding_3 PF01494.14 EIM86745.1 - 1.3e-24 86.9 0.2 2.5e-12 46.5 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM86745.1 - 4.6e-05 23.3 2.8 0.00015 21.6 1.8 2.0 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM86745.1 - 6.9e-05 21.6 1.3 0.011 14.4 0.5 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EIM86745.1 - 0.00013 20.6 1.0 0.00024 19.7 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIM86745.1 - 0.002 17.2 0.7 0.002 17.2 0.5 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EIM86745.1 - 0.0027 16.6 4.1 0.025 13.4 3.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM86745.1 - 0.0046 16.7 1.7 0.82 9.4 0.5 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIM86745.1 - 0.016 15.6 2.0 0.032 14.6 1.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM86745.1 - 0.023 14.5 0.5 0.061 13.1 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM86745.1 - 0.033 13.0 0.9 0.048 12.5 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 EIM86745.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Ribosomal_S5_C PF03719.10 EIM86745.1 - 0.11 11.8 0.1 8.3 5.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain FAD_binding_2 PF00890.19 EIM86745.1 - 0.15 10.9 5.2 0.23 10.2 3.6 1.3 1 0 0 1 1 1 0 FAD binding domain Histone PF00125.19 EIM86746.1 - 7.5e-26 90.0 0.0 9.8e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM86746.1 - 6e-06 26.2 0.0 8.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HAD_2 PF13419.1 EIM86747.1 - 2.1e-17 63.9 0.2 5.7e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM86747.1 - 1.1e-06 28.2 0.1 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM86747.1 - 0.0014 19.0 0.0 0.0066 16.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Carb_kinase PF01256.12 EIM86748.1 - 6.2e-51 173.0 0.0 9.9e-51 172.3 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EIM86748.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase HAD_2 PF13419.1 EIM86749.1 - 1.1e-21 77.8 0.0 1.4e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM86749.1 - 2e-08 34.9 0.0 3.7e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM86749.1 - 8.5e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like G_glu_transpept PF01019.16 EIM86750.1 - 8.2e-150 499.6 2.4 9.5e-150 499.4 1.7 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase BTB PF00651.26 EIM86751.1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_P_40 PF08584.6 EIM86752.1 - 7.9e-15 54.6 0.0 3.9e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit C2 PF00168.25 EIM86752.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain Lipase_3 PF01764.20 EIM86754.1 - 2.2e-34 118.0 0.0 3e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EIM86754.1 - 3.3e-05 23.7 0.0 5.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 EIM86754.1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EIM86754.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein OTT_1508_deam PF14441.1 EIM86755.1 - 5.1e-08 32.8 0.2 1.5e-07 31.3 0.2 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase p450 PF00067.17 EIM86756.1 - 1.7e-37 129.0 0.0 1e-19 70.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIM86757.1 - 0.0026 16.3 0.0 0.0028 16.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribonucleas_3_3 PF14622.1 EIM86758.1 - 7.2e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EIM86758.1 - 7.9e-07 29.5 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EIM86758.1 - 4.8e-06 26.9 0.0 7.7e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain RhoGAP PF00620.22 EIM86759.1 - 1.4e-09 37.7 0.0 3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIM86759.1 - 6.8e-09 35.8 0.0 1.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EIM86759.1 - 6.7e-08 32.1 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GspH PF12019.3 EIM86760.1 - 0.14 12.3 2.9 2.7 8.1 2.0 2.6 1 1 0 1 1 1 0 Type II transport protein GspH SOG2 PF10428.4 EIM86760.1 - 7.4 5.1 9.3 8.8 4.8 6.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.11 EIM86762.1 - 1e-33 116.5 31.7 1e-33 116.5 21.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PACT_coil_coil PF10495.4 EIM86763.1 - 9e-11 41.5 1.2 3e-10 39.8 0.8 2.0 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 EIM86763.1 - 0.0021 17.9 20.4 0.0021 17.9 14.1 11.1 4 2 7 12 12 12 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CDP-OH_P_transf PF01066.16 EIM86764.1 - 5.1e-18 65.2 5.5 5.1e-18 65.2 3.8 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WLM PF08325.5 EIM86765.1 - 5.6e-34 117.6 0.2 2.6e-33 115.4 0.0 1.9 1 1 1 2 2 2 1 WLM domain ubiquitin PF00240.18 EIM86765.1 - 9.7e-11 40.9 0.0 1.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EIM86765.1 - 0.0041 17.6 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 EIM86765.1 - 0.018 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF45 PF01863.12 EIM86765.1 - 0.018 14.8 0.1 0.081 12.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 EIM86765.1 - 0.022 14.8 0.1 0.069 13.1 0.0 1.8 1 1 0 1 1 1 0 Peptidase MA superfamily Oxidored_FMN PF00724.15 EIM86767.1 - 2e-14 53.3 0.0 1.1e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family SUZ PF12752.2 EIM86768.1 - 0.015 15.7 0.4 0.023 15.1 0.3 1.3 1 0 0 1 1 1 0 SUZ domain Aa_trans PF01490.13 EIM86769.1 - 2.7e-81 273.1 16.8 3.4e-81 272.8 11.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIM86769.1 - 0.00017 20.5 18.3 0.00023 20.1 10.6 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF202 PF02656.10 EIM86771.1 - 4.8e-05 23.4 1.9 0.00023 21.3 1.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF914 PF06027.7 EIM86773.1 - 3.7e-103 344.9 9.8 4.4e-103 344.6 6.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EIM86773.1 - 6.5e-05 21.9 11.8 0.00014 20.9 8.1 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIM86773.1 - 1.7 8.6 27.5 0.057 13.4 4.8 3.0 2 1 2 4 4 4 0 EamA-like transporter family DUF4131 PF13567.1 EIM86773.1 - 2.2 7.6 10.8 1.1 8.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TPT PF03151.11 EIM86773.1 - 3.8 7.1 16.4 0.54 9.9 0.2 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family OHCU_decarbox PF09349.5 EIM86774.1 - 2.2e-36 125.5 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase LcrG PF07216.7 EIM86774.1 - 0.14 12.2 0.1 0.56 10.2 0.0 2.0 2 1 0 2 2 2 0 LcrG protein FAD_binding_3 PF01494.14 EIM86775.1 - 8.9e-23 80.9 0.0 3.1e-22 79.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM86775.1 - 3.1e-06 27.0 2.0 7.6e-06 25.8 1.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM86775.1 - 2.3e-05 24.5 0.1 0.00091 19.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM86775.1 - 0.00012 20.8 3.4 0.00068 18.3 0.6 2.3 1 1 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EIM86775.1 - 0.00037 19.1 2.0 0.00049 18.6 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 EIM86775.1 - 0.0008 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.12 EIM86775.1 - 0.0014 17.7 2.0 0.0019 17.3 0.4 1.8 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EIM86775.1 - 0.0016 17.6 1.0 0.99 8.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EIM86775.1 - 0.0031 16.4 3.1 0.0031 16.4 2.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM86775.1 - 0.007 16.7 3.4 0.016 15.6 1.4 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM86775.1 - 0.009 15.7 0.7 0.21 11.3 0.6 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Ribosomal_S5_C PF03719.10 EIM86775.1 - 0.012 14.9 0.1 2.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain GIDA PF01134.17 EIM86775.1 - 0.038 12.8 0.9 0.06 12.2 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EIM86775.1 - 0.046 13.5 1.6 0.23 11.3 1.5 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM86775.1 - 0.12 11.2 5.3 0.21 10.3 3.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.20 EIM86776.1 - 0.00019 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM86776.1 - 0.0003 20.5 0.1 0.22 11.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIM86776.1 - 0.0023 17.3 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 EIM86776.1 - 0.0049 16.1 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EIM86776.1 - 0.006 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EIM86776.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EIM86776.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_hydro_35 PF01301.14 EIM86777.1 - 7.7e-74 248.9 0.7 1.1e-73 248.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EIM86777.1 - 9.3e-48 161.9 11.6 1.9e-47 160.9 8.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EIM86777.1 - 1.6e-39 134.6 4.9 3.6e-21 75.5 1.6 3.8 5 0 0 5 5 5 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EIM86777.1 - 1.7e-24 84.9 0.0 6.7e-24 83.0 0.0 2.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EIM86777.1 - 0.0011 18.1 0.8 0.0056 15.9 0.3 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxidored_FMN PF00724.15 EIM86778.1 - 8.8e-41 140.0 0.0 1.2e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1752 PF08550.5 EIM86779.1 - 6.4e-09 35.2 8.3 1.2e-08 34.3 5.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MTHFR PF02219.12 EIM86780.1 - 1.6e-43 148.8 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EIM86781.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Oxidored_FMN PF00724.15 EIM86782.1 - 3.4e-45 154.5 0.0 4.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UBACT PF02134.16 EIM86782.1 - 0.14 11.7 0.0 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein Aldo_ket_red PF00248.16 EIM86783.1 - 5.1e-69 232.2 0.0 5.8e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIM86783.1 - 0.13 12.2 2.8 0.35 10.8 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family PseudoU_synth_1 PF01416.15 EIM86784.1 - 7.2e-20 71.3 0.0 1.4e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase PI3K_1B_p101 PF10486.4 EIM86786.1 - 0.016 12.8 0.1 0.022 12.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SCA7 PF08313.7 EIM86787.1 - 8.4e-28 95.7 0.1 8.4e-28 95.7 0.1 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain Cut8_N PF14482.1 EIM86787.1 - 0.078 12.9 0.3 0.078 12.9 0.2 2.9 2 1 0 2 2 2 0 Cut8 proteasome-binding domain FAD_binding_3 PF01494.14 EIM86788.1 - 8.3e-18 64.5 0.1 6.6e-16 58.3 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM86788.1 - 1.3e-07 31.4 0.7 3.7e-07 30.0 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM86788.1 - 1.1e-05 24.5 0.8 2.2e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM86788.1 - 9.8e-05 21.4 4.0 0.00012 21.1 1.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM86788.1 - 0.0009 18.4 1.1 0.0015 17.6 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EIM86788.1 - 0.0027 17.6 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM86788.1 - 0.012 16.0 0.2 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM86788.1 - 0.019 13.4 0.3 0.075 11.4 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EIM86788.1 - 0.094 11.5 1.3 0.24 10.2 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIM86788.1 - 0.16 10.8 1.2 0.28 10.0 0.2 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pkinase PF00069.20 EIM86789.1 - 7.1e-70 235.1 0.0 8.3e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86789.1 - 6.9e-31 107.2 0.0 1.7e-30 106.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM86789.1 - 0.01 14.8 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EIM86789.1 - 0.024 14.3 0.1 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RanBP PF00641.13 EIM86792.1 - 4.8e-10 38.3 39.5 4.4e-07 28.8 3.2 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EIM86792.1 - 0.042 13.4 19.0 1.2 8.7 0.2 4.0 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger FdhE PF04216.7 EIM86792.1 - 2.8 7.5 23.8 0.61 9.7 0.8 3.5 2 1 0 3 3 3 0 Protein involved in formate dehydrogenase formation NADH-u_ox-rdase PF10785.4 EIM86793.1 - 2.6e-32 110.9 0.5 3.8e-32 110.3 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EIM86793.1 - 3.1e-14 52.4 0.0 4.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Pantoate_ligase PF02569.10 EIM86794.1 - 3.1e-81 272.1 0.0 4.4e-47 160.1 0.0 2.2 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase PAP2 PF01569.16 EIM86795.1 - 1.8e-13 50.3 10.1 2.3e-13 49.9 6.6 1.4 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EIM86795.1 - 0.15 11.7 0.7 2.6 7.7 0.0 2.4 3 0 0 3 3 3 0 Divergent PAP2 family DUF1211 PF06736.6 EIM86795.1 - 2.6 8.2 6.2 6 7.0 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) DUF2784 PF10861.3 EIM86795.1 - 3.5 7.4 11.4 0.41 10.4 4.5 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) BCS1_N PF08740.6 EIM86796.1 - 1.1e-31 109.9 0.7 1.7e-31 109.2 0.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIM86796.1 - 1.4e-16 60.9 0.0 8.9e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM86796.1 - 0.00092 19.2 0.0 0.0026 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIM86796.1 - 0.0014 19.4 0.0 0.0054 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM86796.1 - 0.0093 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIM86796.1 - 0.015 14.9 0.0 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EIM86796.1 - 0.018 13.9 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIM86796.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIM86796.1 - 0.027 14.0 0.1 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIM86796.1 - 0.027 14.6 0.0 0.079 13.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 EIM86796.1 - 0.057 13.7 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 EIM86796.1 - 0.072 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIM86796.1 - 0.074 12.4 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM86796.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIM86796.1 - 0.093 12.4 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_33 PF13671.1 EIM86796.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM86796.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 EIM86796.1 - 0.19 10.8 0.1 0.89 8.6 0.0 2.0 2 1 1 3 3 3 0 KaiC AAA_PrkA PF08298.6 EIM86796.1 - 0.19 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TIP49 PF06068.8 EIM86796.1 - 0.21 10.2 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus VPS9 PF02204.13 EIM86798.1 - 6.2e-31 106.5 0.1 1.1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EIM86798.1 - 2.4e-05 23.6 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 CUE domain DUF1109 PF06532.6 EIM86800.1 - 0.00038 19.9 0.5 0.00038 19.9 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1109) NVEALA PF14055.1 EIM86800.1 - 0.0078 15.8 1.1 4.4 7.0 0.1 3.3 3 0 0 3 3 3 2 NVEALA protein Cytochrom_B_N PF00033.14 EIM86800.1 - 0.057 12.7 1.5 0.069 12.5 0.0 1.8 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF373 PF04123.8 EIM86800.1 - 0.11 11.5 15.8 0.12 11.4 8.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3810 PF12725.2 EIM86800.1 - 0.94 8.3 7.3 4 6.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) HMG_CoA_synt_C PF08540.5 EIM86801.1 - 1.4e-92 310.2 0.2 1.8e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EIM86801.1 - 1.4e-82 275.4 0.1 2.1e-82 274.8 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EIM86801.1 - 0.099 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EIM86801.1 - 0.1 12.5 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BTB PF00651.26 EIM86802.1 - 1.5e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PGM_PMM_I PF02878.11 EIM86803.1 - 8.7e-37 125.6 0.1 1.4e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EIM86803.1 - 1.9e-25 89.1 0.1 7.7e-25 87.1 0.0 2.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EIM86803.1 - 4e-14 52.7 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIM86803.1 - 2.4e-07 30.6 0.0 6.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Zn_clus PF00172.13 EIM86804.1 - 4.4e-27 93.7 91.5 1.8e-08 34.1 8.1 5.2 4 1 1 5 5 5 5 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4451 PF14616.1 EIM86805.1 - 4.1e-07 29.7 8.0 0.0073 16.0 0.3 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4451) PBP1_TM PF14812.1 EIM86805.1 - 0.011 16.0 5.7 0.35 11.2 0.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-dskA_traR PF01258.12 EIM86805.1 - 0.25 11.1 3.0 17 5.2 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger PGA2 PF07543.7 EIM86805.1 - 1.1 9.0 3.5 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 DZR PF12773.2 EIM86805.1 - 1.6 8.6 5.4 3.3 7.6 0.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon Sigma70_ner PF04546.8 EIM86805.1 - 4.7 6.7 6.4 1.9 8.0 0.2 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region SIR2 PF02146.12 EIM86806.1 - 3.7e-29 101.7 0.0 5.1e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF364 PF04016.7 EIM86806.1 - 0.0032 16.7 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF364) WD40 PF00400.27 EIM86807.1 - 1.2e-40 135.9 19.7 2.2e-08 33.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat HARP PF07443.8 EIM86807.1 - 0.12 11.7 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 HepA-related protein (HARP) ATXN-1_C PF12547.3 EIM86807.1 - 0.47 10.4 2.1 26 4.8 0.3 2.5 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator CTD_bind PF04818.8 EIM86808.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase II-binding domain. PAP2 PF01569.16 EIM86809.1 - 1.6e-21 76.2 1.9 2.3e-21 75.8 0.9 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF3040 PF11239.3 EIM86809.1 - 0.012 15.6 0.1 0.18 11.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) SNF2_N PF00176.18 EIM86810.1 - 2.2e-22 79.2 1.0 5.5e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EIM86810.1 - 1.3e-12 47.5 0.0 4.9e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-C3HC4 PF00097.20 EIM86810.1 - 0.52 10.0 7.6 1.7 8.3 5.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zw10 PF06248.8 EIM86811.1 - 9e-24 83.5 0.0 2.6e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EIM86811.1 - 3.5e-07 29.6 0.0 5.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Methyltransf_16 PF10294.4 EIM86812.1 - 4.7e-14 52.2 0.0 1e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM86812.1 - 1.3e-06 28.9 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM86812.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain STN PF07660.9 EIM86812.1 - 0.026 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain GidB PF02527.10 EIM86812.1 - 0.031 13.4 0.0 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EIM86812.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EIM86813.1 - 6.9e-16 58.0 0.0 2.1e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIM86813.1 - 1.4e-14 54.0 0.0 9.8e-06 24.9 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EIM86813.1 - 0.00012 21.8 0.0 0.087 12.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIM86813.1 - 0.00027 19.9 0.2 0.00065 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM86813.1 - 0.00087 19.3 0.0 0.031 14.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM86813.1 - 0.0069 16.7 0.0 0.036 14.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM86813.1 - 0.017 14.2 0.1 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EIM86813.1 - 0.062 11.7 0.0 0.34 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Glyco_transf_9 PF01075.12 EIM86813.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) p450 PF00067.17 EIM86814.1 - 1.1e-59 202.1 0.0 1.5e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PROL5-SMR PF15621.1 EIM86814.1 - 0.048 14.0 0.4 0.13 12.7 0.3 1.7 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Cript PF10235.4 EIM86816.1 - 3.3e-18 65.8 15.8 5.5e-18 65.1 7.7 2.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT stn_TNFRSF12A PF12191.3 EIM86816.1 - 0.013 15.5 4.2 0.023 14.7 2.9 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Sgf11 PF08209.6 EIM86816.1 - 0.1 11.9 5.3 5.8 6.3 0.2 3.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Gin PF10764.4 EIM86816.1 - 0.11 12.2 7.4 0.56 9.9 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin C1_1 PF00130.17 EIM86816.1 - 0.25 11.1 11.1 3.2 7.5 2.2 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.7 EIM86816.1 - 0.34 10.7 10.1 2.2 8.1 3.3 2.2 2 0 0 2 2 2 0 zinc-ribbons DiS_P_DiS PF06750.8 EIM86816.1 - 0.41 10.4 4.5 0.29 10.9 0.5 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_2 PF13240.1 EIM86816.1 - 0.73 9.3 15.4 3.3 7.3 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.6 EIM86816.1 - 1 9.2 7.4 0.89 9.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 EIM86816.1 - 1.8 7.8 9.9 13 5.1 2.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EIM86816.1 - 2 8.1 11.0 29 4.4 0.0 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 EIM86816.1 - 2.9 7.9 14.8 0.68 9.9 5.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-dskA_traR PF01258.12 EIM86816.1 - 4.3 7.1 8.0 8.8 6.1 0.0 2.9 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_1 PF14446.1 EIM86816.1 - 6.1 6.6 14.1 11 5.8 0.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.7 EIM86816.1 - 8.1 6.3 8.7 13 5.6 0.0 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF4428 PF14471.1 EIM86816.1 - 9.1 6.1 10.2 0.64 9.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) F-box-like PF12937.2 EIM86817.1 - 3e-06 26.8 0.5 5.4e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM86817.1 - 4e-06 26.3 0.4 7.6e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EIM86817.1 - 0.00029 20.6 0.5 0.00059 19.6 0.3 1.6 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EIM86817.1 - 0.015 14.9 0.2 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 TPR repeat DnaJ PF00226.26 EIM86818.1 - 8.4e-26 89.4 0.7 1.7e-25 88.5 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EIM86818.1 - 4.5e-14 52.5 0.0 4.6e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1977) Period_C PF12114.3 EIM86818.1 - 2.1 7.9 13.0 4.9 6.7 9.0 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SSP160 PF06933.6 EIM86818.1 - 6.6 4.5 12.4 9.8 4.0 8.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 EIM86818.1 - 9 4.4 8.3 13 3.9 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein F-box-like PF12937.2 EIM86819.1 - 3.4e-06 26.6 0.4 9e-06 25.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like ubiquitin PF00240.18 EIM86820.1 - 1.4e-34 117.2 0.7 1.4e-34 117.2 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EIM86820.1 - 1.2e-26 92.2 2.5 2.5e-26 91.2 1.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EIM86820.1 - 7.5e-20 70.3 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM86820.1 - 9.8e-06 25.7 0.4 5e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIM86820.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIM86820.1 - 0.0003 20.6 0.6 0.00065 19.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2207 PF09972.4 EIM86820.1 - 0.0046 15.6 0.7 0.0053 15.4 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2407 PF10302.4 EIM86820.1 - 0.0058 16.8 0.8 0.0077 16.4 0.5 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 EIM86820.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Plexin_cytopl PF08337.7 EIM86820.1 - 0.072 11.3 3.1 0.61 8.3 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 EIM86820.1 - 0.087 12.7 0.7 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 IBR domain Stig1 PF04885.8 EIM86820.1 - 0.088 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2870 PF11069.3 EIM86820.1 - 0.13 12.3 1.6 0.14 12.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) AAA PF00004.24 EIM86821.1 - 4.7e-17 62.4 0.0 7.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EIM86821.1 - 5.5e-17 61.5 0.0 1.5e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIM86821.1 - 5.9e-17 61.7 0.0 6.6e-15 55.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EIM86821.1 - 9.5e-10 37.7 0.0 4.1e-08 32.3 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 EIM86821.1 - 2.6e-07 30.3 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EIM86821.1 - 7.7e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM86821.1 - 2e-06 27.9 0.4 0.00056 20.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM86821.1 - 7.4e-06 25.1 0.0 2.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EIM86821.1 - 8.8e-06 25.4 0.5 0.0018 17.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM86821.1 - 1.5e-05 24.6 0.1 5.3e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EIM86821.1 - 3.9e-05 23.3 0.8 0.00026 20.6 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIM86821.1 - 4.1e-05 23.6 0.0 0.0012 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EIM86821.1 - 6.7e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIM86821.1 - 0.00082 19.1 0.2 0.0061 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIM86821.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EIM86821.1 - 0.0038 16.7 0.2 0.08 12.4 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EIM86821.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EIM86821.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EIM86821.1 - 0.0092 15.3 0.1 0.05 13.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIM86821.1 - 0.01 15.4 0.4 0.023 14.2 0.3 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EIM86821.1 - 0.018 14.8 0.0 0.11 12.3 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EIM86821.1 - 0.021 14.5 0.1 0.048 13.3 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EIM86821.1 - 0.024 14.5 0.2 0.11 12.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIM86821.1 - 0.027 13.9 0.3 1 8.7 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain TIP49 PF06068.8 EIM86821.1 - 0.042 12.5 0.0 0.33 9.6 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus MobB PF03205.9 EIM86821.1 - 0.049 13.3 0.0 0.21 11.2 0.0 2.2 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM86821.1 - 0.051 14.3 0.0 0.1 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.10 EIM86821.1 - 0.053 13.1 0.7 3.3 7.3 0.0 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Mg_chelatase PF01078.16 EIM86821.1 - 0.093 11.8 0.0 0.37 9.9 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI TPR_6 PF13174.1 EIM86821.1 - 0.12 12.9 1.1 7.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.18 EIM86821.1 - 0.12 11.0 0.0 0.44 9.3 0.0 1.8 1 1 1 2 2 2 0 SNF2 family N-terminal domain Methyltransf_31 PF13847.1 EIM86821.1 - 0.13 11.8 0.1 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Methyltransferase domain DUF2075 PF09848.4 EIM86821.1 - 0.14 11.1 0.1 0.43 9.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3810 PF12725.2 EIM86822.1 - 0.27 10.0 3.1 0.11 11.3 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Macoilin PF09726.4 EIM86822.1 - 0.35 9.0 12.3 0.44 8.7 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein AKNA PF12443.3 EIM86822.1 - 1.2 9.1 6.0 0.33 10.9 0.2 2.3 2 1 0 2 2 2 0 AT-hook-containing transcription factor Pkinase PF00069.20 EIM86823.1 - 3.4e-11 42.7 0.0 2.9e-10 39.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86823.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Actin PF00022.14 EIM86824.1 - 2.9e-120 401.2 0.0 3.5e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Actin PQ-loop PF04193.9 EIM86825.1 - 4.4e-24 83.7 2.2 1.6e-16 59.5 0.2 3.3 4 0 0 4 4 4 2 PQ loop repeat Pkinase PF00069.20 EIM86826.1 - 0.003 16.7 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM86826.1 - 0.018 14.4 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Sugar_tr PF00083.19 EIM86827.1 - 1.5e-104 350.1 19.0 1.7e-104 349.9 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM86827.1 - 3.9e-24 85.0 21.5 6.1e-22 77.7 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 EIM86827.1 - 0.012 14.6 6.5 0.79 8.6 1.9 2.6 2 1 0 2 2 2 0 Emopamil binding protein DUF1673 PF07895.6 EIM86827.1 - 0.022 14.2 1.9 0.069 12.6 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Prenyltrans PF00432.16 EIM86829.1 - 3.1e-33 113.0 9.3 7e-07 28.7 0.0 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIM86829.1 - 8.1e-20 71.3 0.0 3.2e-17 62.9 0.0 2.8 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIM86829.1 - 0.0016 18.4 0.0 0.028 14.4 0.0 2.8 2 1 1 3 3 3 2 Prenyltransferase-like Pkinase PF00069.20 EIM86832.1 - 6.2e-14 51.7 0.0 7.8e-11 41.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM86832.1 - 0.058 12.4 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase LisH PF08513.6 EIM86833.1 - 2.6e-06 27.0 0.1 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 LisH START PF01852.14 EIM86834.1 - 5.4e-17 61.7 0.2 5.9e-10 38.8 0.0 2.8 3 0 0 3 3 3 2 START domain Phos_pyr_kin PF08543.7 EIM86835.1 - 4.8e-12 45.5 0.0 1.2e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EIM86835.1 - 1.8e-07 30.5 0.3 5.5e-05 22.4 0.0 2.7 2 1 1 3 3 3 2 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EIM86835.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate kinase DUF676 PF05057.9 EIM86836.1 - 1e-40 139.3 0.0 1.6e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EIM86836.1 - 5.5e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIM86836.1 - 0.033 14.0 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM86836.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EIM86836.1 - 0.19 11.0 0.0 0.54 9.5 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family ATG16 PF08614.6 EIM86837.1 - 0.086 12.6 9.9 0.029 14.1 2.4 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Med3 PF11593.3 EIM86837.1 - 0.11 11.6 7.2 0.04 13.1 0.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal UPF0449 PF15136.1 EIM86837.1 - 0.27 11.4 3.8 0.19 11.9 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 MtrG PF04210.8 EIM86837.1 - 0.35 10.5 4.8 1.9 8.2 0.9 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tropomyosin PF00261.15 EIM86837.1 - 0.36 9.8 21.9 1.9 7.5 3.7 2.3 1 1 1 2 2 2 0 Tropomyosin DUF972 PF06156.8 EIM86837.1 - 0.71 10.2 8.7 0.98 9.7 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EIM86837.1 - 0.85 9.3 6.3 0.16 11.6 0.8 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 EIM86837.1 - 1.4 6.7 4.5 2 6.1 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EIM86837.1 - 5.6 5.8 11.7 9.5 5.0 8.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EIM86837.1 - 8.3 6.2 11.0 13 5.6 2.3 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding BrkDBD PF09607.5 EIM86838.1 - 0.048 13.2 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Brinker DNA-binding domain DOPA_dioxygen PF08883.6 EIM86840.1 - 1.9e-26 92.1 0.7 8.1e-19 67.6 0.1 2.1 1 1 1 2 2 2 2 Dopa 4,5-dioxygenase family PALP PF00291.20 EIM86841.1 - 1.6e-56 191.7 0.5 2e-56 191.4 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.20 EIM86842.1 - 2.1e-53 181.5 0.5 2.6e-53 181.2 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EIM86844.1 - 7.7e-36 123.7 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EIM86844.1 - 0.032 14.7 0.0 0.22 12.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain DUF1758 PF05585.7 EIM86844.1 - 0.081 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RrnaAD PF00398.15 EIM86844.1 - 0.084 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EIM86845.1 - 2.9e-12 46.4 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86845.1 - 1.5e-11 44.6 0.0 3.4e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86845.1 - 1.1e-10 42.0 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86845.1 - 5.5e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86845.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM86845.1 - 2.9e-05 23.8 0.0 0.00017 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM86845.1 - 0.0011 18.1 0.3 0.57 9.2 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family TPMT PF05724.6 EIM86845.1 - 0.0023 17.4 0.0 0.0038 16.6 0.0 1.4 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 EIM86845.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EIM86845.1 - 0.046 13.4 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CbiK PF06180.6 EIM86845.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) DUF1792 PF08759.6 EIM86845.1 - 0.073 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Tmemb_14 PF03647.8 EIM86846.1 - 1.6e-15 57.2 4.8 2.1e-15 56.8 3.4 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3529 PF12046.3 EIM86846.1 - 0.016 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) PQ-loop PF04193.9 EIM86847.1 - 2.7e-32 110.0 5.6 4.9e-18 64.4 0.1 2.6 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EIM86847.1 - 0.0051 16.6 7.5 0.24 11.2 0.4 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Neur_chan_memb PF02932.11 EIM86847.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region 7TM_GPCR_Srw PF10324.4 EIM86847.1 - 0.11 11.6 2.1 0.21 10.6 1.5 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MMS19_N PF14500.1 EIM86848.1 - 4.8e-89 298.1 0.1 1.1e-86 290.3 0.0 2.8 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EIM86848.1 - 1.1e-87 294.5 3.4 1.1e-86 291.1 0.2 2.6 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EIM86848.1 - 0.00019 21.6 6.5 0.35 11.1 0.1 6.4 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EIM86848.1 - 0.053 14.0 13.0 0.17 12.3 0.1 7.4 11 0 0 11 11 11 0 HEAT-like repeat Laminin_II PF06009.7 EIM86849.1 - 0.038 13.7 3.1 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Laminin Domain II Ku_PK_bind PF08785.6 EIM86849.1 - 0.077 12.8 0.9 1.3 8.9 0.0 2.9 2 1 0 3 3 3 0 Ku C terminal domain like MtrC PF04211.8 EIM86850.1 - 0.0048 15.9 0.2 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit C DUF3561 PF12084.3 EIM86850.1 - 1.9 8.3 9.0 1.2 8.9 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Paf1 PF03985.8 EIM86851.1 - 6.3e-57 193.2 0.0 8.8e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Paf1 IF4E PF01652.13 EIM86853.1 - 1.5e-44 151.4 0.1 9.9e-34 116.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic initiation factor 4E Kei1 PF08552.6 EIM86854.1 - 3.8e-43 147.3 1.3 5.1e-43 146.9 0.9 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 EIM86854.1 - 0.00049 20.0 2.1 0.001 19.0 1.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) FixQ PF05545.6 EIM86854.1 - 0.026 14.1 0.5 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1469 PF07332.6 EIM86854.1 - 3.9 7.2 8.2 1.1 9.0 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) zf-HIT PF04438.11 EIM86856.1 - 2.2e-06 27.1 9.6 3.2e-06 26.6 6.6 1.2 1 0 0 1 1 1 1 HIT zinc finger Tnp_zf-ribbon_2 PF13842.1 EIM86856.1 - 3.6 8.0 6.7 5.7 7.4 4.7 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon CRAL_TRIO PF00650.15 EIM86857.1 - 2.6e-30 105.0 0.0 3.7e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM86857.1 - 0.0019 18.3 0.1 0.0074 16.3 0.0 2.1 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain WRW PF10206.4 EIM86857.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f HABP4_PAI-RBP1 PF04774.10 EIM86857.1 - 0.69 10.4 7.1 1.5 9.3 4.9 1.6 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Aminotran_3 PF00202.16 EIM86858.1 - 3.3e-74 249.7 0.0 4.5e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIM86858.1 - 0.0044 16.0 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II C_GCAxxG_C_C PF09719.5 EIM86858.1 - 0.062 13.1 0.5 2.7 7.8 0.1 3.1 2 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) HECT PF00632.20 EIM86859.1 - 4.8e-80 269.0 0.0 6.8e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EIM86859.1 - 0.47 10.3 2.9 4.9 7.1 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PHF5 PF03660.9 EIM86860.1 - 5.6e-51 171.1 8.0 6.2e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EIM86860.1 - 0.27 11.0 14.7 0.047 13.5 4.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EIM86860.1 - 0.43 10.3 14.3 2.3 7.9 0.3 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EIM86860.1 - 1.3 8.7 14.1 0.034 13.8 3.7 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 EIM86860.1 - 6.6 4.2 6.4 7.2 4.1 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 EIM86860.1 - 9.6 6.0 13.0 10 5.9 4.9 2.7 1 1 0 1 1 1 0 zinc-ribbons ZZ PF00569.12 EIM86861.1 - 2.3e-18 65.4 52.0 4.3e-07 29.3 3.0 6.3 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.19 EIM86861.1 - 8.6e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DZR PF12773.2 EIM86861.1 - 0.097 12.5 0.1 0.097 12.5 0.1 6.0 6 1 0 6 6 6 0 Double zinc ribbon DPBB_1 PF03330.13 EIM86862.1 - 3.9e-06 26.7 0.5 3.9e-06 26.7 0.3 3.4 4 1 0 4 4 4 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel zf-DHHC PF01529.15 EIM86863.1 - 2.2e-26 92.3 0.0 1.6e-24 86.2 0.0 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase DSPc PF00782.15 EIM86864.1 - 4.6e-30 103.9 0.0 5.4e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM86864.1 - 0.002 17.5 0.1 0.0025 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SSF PF00474.12 EIM86864.1 - 0.017 13.7 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family TatD_DNase PF01026.16 EIM86864.1 - 0.035 13.3 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase DUF952 PF06108.7 EIM86865.1 - 7.4e-18 64.2 0.0 1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Amidase PF01425.16 EIM86866.1 - 2.3e-102 343.0 0.0 2.8e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.17 EIM86867.1 - 4.4e-31 106.3 0.8 5.6e-15 54.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM86867.1 - 3.9e-27 94.0 0.0 5.8e-09 35.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM86867.1 - 2.5e-17 62.4 0.0 4.6e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 EIM86867.1 - 0.033 14.1 0.0 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family GFO_IDH_MocA PF01408.17 EIM86868.1 - 5.2e-25 88.2 0.0 7.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIM86868.1 - 7.5e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIM86868.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 EIM86870.1 - 5.8e-63 213.0 0.0 1.8e-62 211.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HIT PF01230.18 EIM86871.1 - 0.021 15.3 0.0 2.9 8.4 0.0 2.7 3 0 0 3 3 3 0 HIT domain Med4 PF10018.4 EIM86872.1 - 2.9e-26 92.0 0.0 3.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 EIM86872.1 - 0.024 14.3 0.6 0.032 13.8 0.4 1.1 1 0 0 1 1 1 0 Mnd1 family Mod_r PF07200.8 EIM86872.1 - 0.059 13.2 0.4 0.087 12.7 0.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Phage_lysis PF03245.8 EIM86872.1 - 0.071 13.1 1.1 0.1 12.5 0.7 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Herpes_UL51 PF04540.8 EIM86872.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL51 protein Med21 PF11221.3 EIM86872.1 - 9.7 6.1 6.5 1.4 8.9 1.6 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AAA_12 PF13087.1 EIM86873.1 - 1.2e-35 122.7 0.0 1.9e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM86873.1 - 8.3e-31 107.3 0.0 1.1e-29 103.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM86873.1 - 1.5e-07 31.0 0.0 3.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIM86873.1 - 1.4e-06 28.0 0.0 0.00014 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EIM86873.1 - 0.074 12.0 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prenyltrans PF00432.16 EIM86874.1 - 5.2e-36 121.8 7.5 1.2e-09 37.5 0.0 7.6 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIM86874.1 - 1.6e-25 89.7 2.7 5e-14 52.6 0.2 5.3 2 2 3 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIM86874.1 - 6.7e-24 83.9 0.5 5.1e-10 39.3 0.2 6.1 4 2 2 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 EIM86874.1 - 1.5e-08 34.2 2.6 0.0051 16.0 0.0 5.3 2 1 2 6 6 6 3 Pectic acid lyase A2M_comp PF07678.9 EIM86874.1 - 0.075 12.2 0.7 0.6 9.2 0.1 2.7 3 1 2 5 5 5 0 A-macroglobulin complement component Actin PF00022.14 EIM86875.1 - 2.7e-32 111.6 0.0 4.8e-32 110.8 0.0 1.4 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.21 EIM86876.1 - 1.7e-22 78.7 0.0 2e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SET PF00856.23 EIM86877.1 - 1.8e-07 31.6 0.2 1.8e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 SET domain Vma12 PF11712.3 EIM86878.1 - 1.3e-13 50.8 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase WW PF00397.21 EIM86879.1 - 0.0033 17.2 6.5 0.0033 17.2 4.5 2.5 2 0 0 2 2 2 1 WW domain PMM PF03332.8 EIM86880.1 - 8.5e-109 362.2 0.6 1e-108 362.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EIM86880.1 - 5.1e-05 22.9 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIM86880.1 - 0.019 14.3 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase F-box-like PF12937.2 EIM86881.1 - 8e-08 31.8 0.1 2.3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM86881.1 - 0.00084 19.0 3.9 2.7 7.7 0.0 4.4 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EIM86881.1 - 0.06 12.9 2.9 23 4.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Ank_4 PF13637.1 EIM86882.1 - 0.04 14.4 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SurE PF01975.12 EIM86883.1 - 1.4e-36 125.6 2.6 1.9e-36 125.1 1.8 1.2 1 0 0 1 1 1 1 Survival protein SurE DNA_pol_B PF00136.16 EIM86884.1 - 2.1e-147 491.6 0.7 3e-147 491.1 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIM86884.1 - 7.6e-91 304.3 0.0 1.2e-90 303.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIM86884.1 - 1.6e-22 79.2 6.5 1.6e-22 79.2 4.5 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EIM86884.1 - 4.1e-05 23.2 0.1 8.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 EIM86884.1 - 0.0012 17.6 1.3 0.0068 15.1 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 EIM86884.1 - 0.0019 18.0 0.2 0.0058 16.4 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.15 EIM86884.1 - 0.015 14.7 0.1 0.046 13.2 0.1 1.8 1 0 0 1 1 1 0 3'-5' exonuclease DnaJ-X PF14308.1 EIM86885.1 - 2.4e-53 180.4 0.1 2.4e-53 180.4 0.1 2.7 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIM86885.1 - 9.1e-27 92.5 1.9 3.3e-26 90.7 1.3 2.1 1 0 0 1 1 1 1 DnaJ domain HA PF03457.9 EIM86885.1 - 0.014 15.4 0.6 0.067 13.3 0.0 2.4 3 0 0 3 3 3 0 Helicase associated domain CCDC-167 PF15188.1 EIM86885.1 - 4.5 7.2 15.6 9.8 6.2 1.3 4.0 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 M20_dimer PF07687.9 EIM86886.1 - 5.5e-09 35.7 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIM86886.1 - 5.2e-08 32.6 0.0 8.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 T2SM_b PF10741.4 EIM86888.1 - 0.04 13.5 0.2 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Actin PF00022.14 EIM86889.1 - 7.5e-27 93.7 0.0 6.4e-11 41.2 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EIM86889.1 - 1.4e-05 23.8 1.2 0.0064 15.1 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF3552 PF12072.3 EIM86890.1 - 0.014 14.5 3.0 0.025 13.7 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rossmann-like PF10727.4 EIM86890.1 - 0.042 13.5 0.1 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain SIC PF03482.8 EIM86891.1 - 0.0076 15.8 0.7 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 sic protein zf-C2H2 PF00096.21 EIM86892.1 - 0.017 15.4 1.3 0.031 14.6 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2110 PF09883.4 EIM86892.1 - 0.037 13.6 0.0 0.04 13.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) DivIC PF04977.10 EIM86892.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2_4 PF13894.1 EIM86892.1 - 0.26 11.7 1.5 0.58 10.6 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger RCC1 PF00415.13 EIM86894.1 - 5.9e-17 61.6 2.7 0.00033 20.8 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM86894.1 - 4.7e-10 38.8 16.0 1.8e-06 27.3 0.4 6.0 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EIM86894.1 - 4.6e-05 23.0 0.3 9e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM86894.1 - 0.00034 20.1 0.3 0.00066 19.2 0.2 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EIM86894.1 - 0.0082 16.5 0.0 0.022 15.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_N_3 PF13417.1 EIM86895.1 - 1.5e-12 47.5 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM86895.1 - 1.8e-08 34.2 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM86895.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM86895.1 - 0.0039 17.1 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM86895.1 - 0.021 14.9 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM86895.1 - 0.022 15.2 0.1 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain End_N_terminal PF12218.3 EIM86895.1 - 0.047 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase PAS_4 PF08448.5 EIM86895.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold CKS PF01111.14 EIM86895.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit FAT PF02259.18 EIM86896.1 - 9.8e-123 409.5 7.4 9.8e-123 409.5 5.1 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIM86896.1 - 7.9e-58 195.7 0.3 1.4e-57 194.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EIM86896.1 - 4.4e-51 172.9 2.1 5.5e-49 166.1 0.1 4.9 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EIM86896.1 - 8.5e-36 122.0 0.2 8.5e-36 122.0 0.2 2.9 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EIM86896.1 - 5.3e-19 68.2 3.9 0.016 15.4 0.0 9.5 4 2 5 9 9 9 4 HEAT repeats FATC PF02260.15 EIM86896.1 - 1.5e-15 56.2 1.0 3.7e-15 55.0 0.7 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EIM86896.1 - 1.1e-10 41.6 8.9 0.027 14.9 0.0 10.5 8 2 3 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EIM86896.1 - 1.3e-10 40.4 12.3 0.64 10.2 0.0 11.2 12 0 0 12 12 11 2 HEAT repeat TPR_19 PF14559.1 EIM86896.1 - 0.00016 21.9 0.0 0.35 11.2 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat Cohesin_HEAT PF12765.2 EIM86896.1 - 0.00087 19.1 0.3 0.12 12.3 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion TPR_7 PF13176.1 EIM86896.1 - 0.0074 16.0 2.0 3.2 7.7 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Cnd1 PF12717.2 EIM86896.1 - 0.0091 15.8 5.4 11 5.8 0.1 5.3 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 TPR_11 PF13414.1 EIM86896.1 - 1.2 8.8 7.7 0.63 9.7 0.0 4.1 6 0 0 6 6 6 0 TPR repeat DUF3439 PF11921.3 EIM86897.1 - 1.7 8.3 5.0 0.72 9.6 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Polysacc_deac_1 PF01522.16 EIM86898.1 - 2.1e-26 91.9 0.0 3.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIM86898.1 - 0.0023 16.8 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CNH PF00780.17 EIM86899.1 - 1.8e-71 240.7 0.0 2.7e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIM86899.1 - 1.9e-39 134.7 0.1 1.1e-38 132.1 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIM86899.1 - 1.5e-37 129.2 0.0 2.3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EIM86899.1 - 7.1e-11 41.6 0.1 1.5e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EIM86899.1 - 0.00016 21.7 0.0 0.00062 19.9 0.0 2.0 2 0 0 2 2 2 1 PH domain Pyridox_ox_2 PF12900.2 EIM86900.1 - 9.1e-30 103.3 0.0 1.9e-29 102.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ELMO_CED12 PF04727.8 EIM86901.1 - 1.3e-26 93.1 0.0 2.3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EIM86901.1 - 1.4e-14 54.1 0.3 5.7e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Sec1 PF00995.18 EIM86902.1 - 6.4e-137 457.5 0.0 7.7e-137 457.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family BRAP2 PF07576.7 EIM86903.1 - 2e-23 82.0 0.0 3.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EIM86903.1 - 3.2e-19 68.8 3.0 7.6e-19 67.5 2.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EIM86903.1 - 4.3e-09 36.0 9.7 4.3e-09 36.0 6.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIM86903.1 - 4.7e-05 22.9 7.0 0.00012 21.6 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM86903.1 - 5.7e-05 23.1 3.8 0.00017 21.5 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIM86903.1 - 0.00015 21.4 6.6 0.00015 21.4 4.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIM86903.1 - 0.00016 21.2 7.3 0.00016 21.2 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EIM86903.1 - 0.00034 20.1 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EIM86903.1 - 0.00059 19.7 9.3 0.00059 19.7 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EIM86903.1 - 0.00099 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LPP PF04728.8 EIM86903.1 - 0.013 15.2 0.1 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Baculo_RING PF05883.6 EIM86903.1 - 0.019 14.7 0.2 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EIM86903.1 - 0.024 14.3 7.8 0.11 12.2 1.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EIM86903.1 - 0.036 13.9 6.0 0.076 12.8 4.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DivIC PF04977.10 EIM86903.1 - 0.045 13.2 13.8 0.037 13.5 2.2 2.7 2 1 0 2 2 2 0 Septum formation initiator RRM_5 PF13893.1 EIM86903.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlaC_arch PF05377.6 EIM86903.1 - 0.16 11.9 1.7 14 5.6 0.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-RING_4 PF14570.1 EIM86903.1 - 0.17 11.5 5.7 0.44 10.1 4.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4071 PF13281.1 EIM86903.1 - 0.26 10.0 6.1 0.37 9.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) TerY-C PF15616.1 EIM86903.1 - 4.6 7.1 16.3 0.89 9.4 3.4 2.4 1 1 1 2 2 2 0 TerY-C metal binding domain Mnd1 PF03962.10 EIM86903.1 - 5.8 6.5 15.0 11 5.6 10.4 1.3 1 0 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 EIM86903.1 - 8.3 6.2 26.0 9.3 6.1 0.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EIM86903.1 - 9.5 3.9 8.5 13 3.4 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NUDIX PF00293.23 EIM86904.1 - 3.6e-13 49.3 0.0 6.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_3 PF07859.8 EIM86905.1 - 1e-11 44.8 0.0 6.4e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM86905.1 - 6.7e-09 34.9 0.1 1e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM86905.1 - 4e-07 29.8 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIM86905.1 - 8.1e-06 24.9 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIM86905.1 - 0.00011 22.2 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EIM86905.1 - 0.0016 17.3 0.0 0.0023 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase F-box-like PF12937.2 EIM86907.1 - 5.8e-12 45.1 0.5 2e-11 43.4 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM86907.1 - 1.2 8.8 4.7 58 3.5 3.3 3.1 1 1 0 1 1 1 0 F-box domain Carn_acyltransf PF00755.15 EIM86908.1 - 1.1e-143 479.4 0.0 1.2e-143 479.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase COesterase PF00135.23 EIM86909.1 - 1.1e-99 334.6 0.3 5.6e-99 332.2 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86909.1 - 6.1e-05 22.6 0.2 0.0003 20.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86909.1 - 8.4e-05 21.8 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_76 PF03663.9 EIM86910.1 - 5.4e-43 147.7 20.3 6.8e-43 147.4 14.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3080 PF11279.3 EIM86910.1 - 0.058 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Pectate_lyase PF03211.8 EIM86910.1 - 0.1 11.9 0.5 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Pectate lyase Glyco_hydro_18 PF00704.23 EIM86911.1 - 8.5e-08 32.0 0.5 1.1e-07 31.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_L37ae PF01780.14 EIM86912.1 - 1.2e-39 134.0 11.0 1.3e-39 133.8 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIM86912.1 - 0.0027 17.4 2.3 0.0044 16.8 1.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 EIM86912.1 - 0.0048 16.7 1.3 0.0064 16.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-BED PF02892.10 EIM86912.1 - 0.0094 15.6 2.7 0.32 10.8 0.0 2.3 1 1 1 2 2 2 1 BED zinc finger zf-FCS PF06467.9 EIM86912.1 - 0.032 13.8 1.2 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 EIM86912.1 - 0.054 13.1 0.8 0.076 12.6 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EIM86912.1 - 0.095 11.9 0.2 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIM86912.1 - 0.1 12.1 3.0 1 8.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_2 PF03107.11 EIM86912.1 - 0.11 12.6 2.7 0.6 10.2 0.3 2.3 2 0 0 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.5 EIM86912.1 - 0.16 11.9 1.4 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 EIM86912.1 - 0.18 11.5 1.7 0.27 10.9 1.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 EIM86912.1 - 0.33 10.6 3.0 0.59 9.8 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 EIM86912.1 - 1.2 9.5 5.1 3.3 8.1 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 EIM86912.1 - 1.6 8.3 4.6 2.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Prok-RING_2 PF14445.1 EIM86912.1 - 1.6 8.7 5.1 2.8 7.9 3.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 adh_short PF00106.20 EIM86913.1 - 4.3e-25 88.5 0.0 6.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM86913.1 - 6.7e-13 48.9 0.0 9.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EIM86913.1 - 5.1e-07 29.1 0.0 6.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM86913.1 - 2.9e-06 27.4 0.0 5.3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM86913.1 - 3.5e-06 26.8 0.0 1.5e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 KR domain zf-CCCH PF00642.19 EIM86914.1 - 4.6e-12 45.3 20.2 9.1e-05 22.0 0.6 5.2 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EIM86914.1 - 0.02 14.3 17.0 0.62 9.6 1.4 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain Nucleoplasmin PF03066.10 EIM86914.1 - 3.4 7.1 10.2 5.4 6.5 7.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EIM86914.1 - 3.6 5.9 9.6 7.7 4.8 6.7 1.5 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EIM86914.1 - 8.9 5.2 7.1 12 4.7 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1712 PF08217.6 EIM86915.1 - 5.2e-18 64.6 0.0 7.6e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Dak1 PF02733.12 EIM86916.1 - 1.4e-115 385.3 1.0 2.3e-115 384.6 0.7 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIM86916.1 - 1e-43 149.0 4.5 1.8e-43 148.2 3.1 1.4 1 0 0 1 1 1 1 DAK2 domain UCH PF00443.24 EIM86918.1 - 2.3e-78 263.0 0.0 4.3e-78 262.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM86918.1 - 2.6e-19 69.7 0.0 5.1e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIM86918.1 - 1.6e-12 47.6 0.5 5e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 DUSP domain zf-FPG_IleRS PF06827.9 EIM86918.1 - 0.12 12.0 1.3 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS USP7_C2 PF14533.1 EIM86918.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Zn-ribbon_8 PF09723.5 EIM86918.1 - 0.48 10.4 3.6 2.4 8.2 0.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Pro-kuma_activ PF09286.6 EIM86919.1 - 7.7e-37 126.5 0.1 7e-36 123.3 0.1 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Sugar_tr PF00083.19 EIM86920.1 - 2.8e-128 428.3 24.5 3.2e-128 428.1 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM86920.1 - 2.1e-24 85.9 34.6 7.6e-17 61.0 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ytp1 PF10355.4 EIM86922.1 - 6.6e-69 232.1 17.4 6.6e-69 232.1 12.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIM86922.1 - 2.5e-27 94.5 1.7 2.5e-27 94.5 1.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3040 PF11239.3 EIM86922.1 - 0.6 10.2 7.1 4.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Cellulase PF00150.13 EIM86923.1 - 4e-12 45.9 0.1 1.2e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2284 PF10050.4 EIM86923.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Amidase PF01425.16 EIM86924.1 - 2e-103 346.6 2.1 2.3e-103 346.4 1.4 1.0 1 0 0 1 1 1 1 Amidase CAP_GLY PF01302.20 EIM86925.1 - 8.7e-26 89.4 2.4 1.5e-25 88.6 1.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EIM86925.1 - 3.3e-24 84.9 0.1 5.2e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIM86925.1 - 6.6e-05 22.2 0.0 0.0004 19.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Pyridoxal_deC PF00282.14 EIM86926.1 - 7.9e-68 228.5 0.0 1.1e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIM86926.1 - 0.0015 17.3 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V CN_hydrolase PF00795.17 EIM86927.1 - 4.6e-28 97.8 0.0 5.6e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_3 PF01764.20 EIM86928.1 - 2.6e-24 85.4 0.1 3.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EIM86928.1 - 0.0051 16.2 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EIM86928.1 - 0.0055 16.2 1.0 0.012 15.1 0.3 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM86928.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM86928.1 - 0.027 14.3 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family M20_dimer PF07687.9 EIM86928.1 - 0.084 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase dimerisation domain DUF2974 PF11187.3 EIM86928.1 - 0.13 11.6 0.1 0.58 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) COesterase PF00135.23 EIM86929.1 - 2.2e-98 330.3 0.1 3.4e-97 326.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIM86929.1 - 0.00015 21.0 0.2 0.00026 20.2 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIM86929.1 - 0.0078 15.8 0.1 0.024 14.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM86930.1 - 1.1e-98 331.3 0.0 1e-96 324.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86930.1 - 7.1e-05 22.4 0.2 0.00034 20.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86930.1 - 7.4e-05 22.0 0.2 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EIM86931.1 - 3.6e-100 336.1 0.0 1.4e-97 327.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM86931.1 - 0.0019 17.8 0.0 0.0046 16.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM86931.1 - 0.0054 15.9 0.3 0.0089 15.2 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pro_dh PF01619.13 EIM86932.1 - 3.1e-34 118.3 0.2 1.1e-13 50.8 0.0 4.0 3 1 0 3 3 3 3 Proline dehydrogenase Pheromone PF08015.6 EIM86932.1 - 1.3 9.8 9.6 4.2 8.2 2.1 2.9 2 0 0 2 2 2 0 Fungal mating-type pheromone HSF_DNA-bind PF00447.12 EIM86933.1 - 6.2e-35 119.5 0.7 6.2e-35 119.5 0.5 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding F-box-like PF12937.2 EIM86934.1 - 7.5e-05 22.3 1.5 0.00015 21.3 0.6 2.0 2 0 0 2 2 2 1 F-box-like HopJ PF08888.6 EIM86934.1 - 0.21 11.6 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 HopJ type III effector protein Tash_PEST PF07708.6 EIM86936.1 - 7.9 6.5 6.8 2 8.4 1.1 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Mt_ATP-synt_B PF05405.9 EIM86937.1 - 3.7e-40 137.0 11.4 4.4e-40 136.7 7.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cullin_binding PF03556.10 EIM86937.1 - 0.069 13.2 0.6 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Cullin binding DASH_Duo1 PF08651.5 EIM86937.1 - 2.8 7.5 8.7 3.5 7.2 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 Dynamin_M PF01031.15 EIM86938.1 - 5.7e-109 363.4 0.0 9.3e-109 362.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIM86938.1 - 2.2e-53 180.5 0.0 4e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIM86938.1 - 3.6e-30 103.7 2.1 2.6e-29 100.9 0.6 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM86938.1 - 0.0055 16.6 0.1 0.045 13.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.3 EIM86938.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Miro PF08477.8 EIM86938.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein BCS1_N PF08740.6 EIM86939.1 - 2.9e-30 105.2 1.0 5.3e-30 104.4 0.7 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIM86939.1 - 6.2e-15 55.5 0.0 1.7e-13 50.9 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM86939.1 - 0.00013 21.9 0.9 0.00035 20.6 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIM86939.1 - 0.00046 20.9 0.5 0.0036 18.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EIM86939.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIM86939.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EIM86939.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIM86939.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM86939.1 - 0.052 13.3 1.5 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EIM86939.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EIM86939.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIM86939.1 - 0.083 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EIM86939.1 - 0.087 11.9 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.9 EIM86939.1 - 0.09 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIM86939.1 - 0.1 12.2 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 EIM86939.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EIM86939.1 - 0.15 12.3 2.3 0.2 11.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain SYS1 PF09801.4 EIM86940.1 - 2.9e-26 92.2 3.2 6.4e-19 68.3 3.0 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.16 EIM86941.1 - 6e-86 288.2 0.4 8.7e-86 287.6 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EIM86941.1 - 8.2e-41 139.5 1.8 1.3e-40 138.8 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM86941.1 - 5.6e-07 29.4 0.1 1.3e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM86941.1 - 1.5e-05 25.0 0.6 6e-05 23.0 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIM86941.1 - 4.7e-05 22.9 2.8 0.00012 21.6 1.7 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EIM86941.1 - 0.024 13.8 0.3 0.52 9.4 0.1 2.2 2 0 0 2 2 2 0 Secretory lipase AXE1 PF05448.7 EIM86941.1 - 0.084 11.3 0.0 0.19 10.2 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIM86941.1 - 0.16 11.3 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Nro1 PF12753.2 EIM86942.1 - 0.00055 19.0 1.2 0.001 18.0 0.3 1.8 2 0 0 2 2 2 1 Nuclear pore complex subunit Nro1 SH3BP5 PF05276.9 EIM86942.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Transketolase_N PF00456.16 EIM86943.1 - 9.1e-19 67.4 1.1 1.3e-17 63.6 0.8 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EIM86943.1 - 7.9e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EIM86943.1 - 7.8e-06 25.5 0.0 3.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.19 EIM86943.1 - 1.7e-05 24.3 0.4 4.1e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Mito_carr PF00153.22 EIM86944.1 - 1.8e-49 165.3 0.0 7e-20 70.5 0.0 4.4 3 3 0 3 3 3 3 Mitochondrial carrier protein DAGAT PF03982.8 EIM86945.1 - 2.7e-98 328.3 0.0 3.2e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3429 PF11911.3 EIM86945.1 - 0.036 14.0 2.4 0.064 13.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Vint PF14623.1 EIM86945.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Hint-domain AAA PF00004.24 EIM86946.1 - 1.1e-96 320.0 0.0 3.3e-47 159.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EIM86946.1 - 1.6e-19 69.6 0.8 5.9e-18 64.5 0.4 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EIM86946.1 - 4.8e-14 51.9 0.0 8.7e-06 24.9 0.0 3.0 4 0 0 4 4 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIM86946.1 - 1.2e-13 51.3 0.0 1.3e-07 31.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIM86946.1 - 5.3e-13 49.0 0.0 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIM86946.1 - 1.5e-12 47.4 0.5 5e-06 26.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIM86946.1 - 4.5e-12 46.8 0.0 0.00037 21.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIM86946.1 - 1.1e-11 44.9 0.2 0.0013 18.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM86946.1 - 1.3e-10 41.6 0.0 0.0012 18.8 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.12 EIM86946.1 - 1.9e-10 40.2 0.0 3.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 EIM86946.1 - 1.5e-09 37.1 0.0 0.001 17.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EIM86946.1 - 3.3e-08 33.4 0.0 0.0037 17.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EIM86946.1 - 3.3e-08 32.8 0.0 0.0094 15.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EIM86946.1 - 4e-08 32.8 2.4 0.02 14.2 0.0 3.8 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EIM86946.1 - 4.9e-08 32.5 0.0 0.0036 16.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EIM86946.1 - 3.6e-07 29.5 0.4 0.03 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EIM86946.1 - 4.4e-07 30.0 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.5 EIM86946.1 - 5.5e-07 29.3 0.1 3.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.1 EIM86946.1 - 5.7e-07 29.1 2.3 0.018 14.7 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain KaiC PF06745.8 EIM86946.1 - 1.2e-06 27.8 1.0 0.42 9.6 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EIM86946.1 - 2e-06 28.1 0.2 0.036 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 EIM86946.1 - 2.7e-06 26.4 0.2 0.0094 14.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 EIM86946.1 - 2.8e-06 27.0 0.1 0.063 12.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EIM86946.1 - 3e-06 27.1 0.2 0.0036 17.1 0.0 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EIM86946.1 - 5e-06 26.5 0.0 0.084 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EIM86946.1 - 5.5e-06 25.5 0.0 0.0039 16.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EIM86946.1 - 7e-06 25.6 0.0 0.19 11.1 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EIM86946.1 - 1.2e-05 25.6 0.0 0.046 14.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EIM86946.1 - 1.2e-05 25.3 0.0 0.3 11.1 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIM86946.1 - 1.4e-05 24.9 0.0 0.56 9.8 0.1 3.7 2 1 1 3 3 3 2 Archaeal ATPase Bac_DnaA PF00308.13 EIM86946.1 - 1.9e-05 24.4 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.11 EIM86946.1 - 4.9e-05 22.6 0.2 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EIM86946.1 - 0.00013 21.6 0.0 0.54 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EIM86946.1 - 0.00014 21.5 0.0 0.52 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIM86946.1 - 0.00021 21.0 0.1 0.56 9.8 0.0 3.4 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EIM86946.1 - 0.00057 18.9 0.0 0.74 8.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EIM86946.1 - 0.00076 18.4 0.1 0.19 10.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain T2SE PF00437.15 EIM86946.1 - 0.0024 16.8 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EIM86946.1 - 0.0025 17.4 0.1 2.9 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EIM86946.1 - 0.0026 17.3 0.0 0.66 9.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EIM86946.1 - 0.0074 15.4 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase NTPase_1 PF03266.10 EIM86946.1 - 0.019 14.6 0.4 5.6 6.6 0.0 3.3 3 0 0 3 3 3 0 NTPase UPF0079 PF02367.12 EIM86946.1 - 0.03 13.9 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EIM86946.1 - 0.04 12.9 0.2 1 8.3 0.0 2.7 2 2 2 4 4 4 0 KAP family P-loop domain Zot PF05707.7 EIM86946.1 - 0.055 12.9 0.2 13 5.2 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EIM86946.1 - 0.097 12.0 1.0 8.5 5.7 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain KTI12 PF08433.5 EIM86946.1 - 0.13 11.4 0.0 8.3 5.5 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UFD1 PF03152.9 EIM86946.1 - 0.13 11.3 0.0 0.36 9.9 0.0 1.6 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 CENP-B_dimeris PF09026.5 EIM86946.1 - 0.16 12.2 2.4 0.49 10.6 1.6 1.9 2 0 0 2 2 1 0 Centromere protein B dimerisation domain SKI PF01202.17 EIM86946.1 - 0.18 11.6 2.0 7.1 6.4 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase Torsin PF06309.6 EIM86946.1 - 0.18 11.6 0.0 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Torsin RhoGEF PF00621.15 EIM86948.1 - 3.1e-67 225.9 2.9 6e-35 120.7 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 EIM86948.1 - 3.7e-62 210.2 0.0 5.6e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIM86948.1 - 6.7e-16 58.4 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIM86948.1 - 6.5e-08 32.7 0.0 1.6e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 PH domain DEP PF00610.16 EIM86948.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_23 PF13489.1 EIM86949.1 - 2.6e-14 53.2 0.0 4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86949.1 - 1.8e-12 47.5 0.0 5.5e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86949.1 - 2e-11 44.4 0.0 3.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM86949.1 - 4.8e-10 39.6 0.0 9.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86949.1 - 1e-08 35.5 0.0 3.1e-08 34.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM86949.1 - 8.6e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIM86949.1 - 0.00028 20.1 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EIM86949.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIM86949.1 - 0.0015 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIM86949.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIM86949.1 - 0.0034 16.4 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 EIM86949.1 - 0.0055 16.3 0.0 0.2 11.2 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.6 EIM86949.1 - 0.0099 15.3 0.0 0.037 13.4 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.1 EIM86949.1 - 0.032 15.0 0.0 0.1 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIM86949.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EIM86949.1 - 0.098 11.9 0.0 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain APH PF01636.18 EIM86950.1 - 6e-12 45.8 0.6 7.9e-12 45.4 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM86950.1 - 2.5e-06 27.2 0.0 4.8e-06 26.3 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EIM86950.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase MHC_I_2 PF14586.1 EIM86950.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Kdo PF06293.9 EIM86950.1 - 0.076 12.0 0.2 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EIM86950.1 - 0.079 11.5 0.0 4.1 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EIM86950.1 - 0.12 11.6 0.1 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family AAA PF00004.24 EIM86951.1 - 1.1e-59 200.4 0.0 5.2e-44 149.6 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EIM86951.1 - 3.4e-22 78.2 0.6 9.6e-22 76.8 0.4 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EIM86951.1 - 2e-10 40.9 0.9 0.0039 17.1 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIM86951.1 - 7.6e-09 36.4 0.0 0.0022 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIM86951.1 - 9.3e-07 28.6 0.1 0.096 12.4 0.0 3.7 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIM86951.1 - 1.1e-06 28.7 3.3 0.13 12.4 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EIM86951.1 - 4.2e-06 26.7 0.0 0.0015 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIM86951.1 - 9.2e-06 25.9 0.0 0.051 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIM86951.1 - 3e-05 23.4 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIM86951.1 - 3.5e-05 22.9 0.0 0.31 10.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 EIM86951.1 - 5.9e-05 22.2 0.0 0.002 17.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIM86951.1 - 6.6e-05 22.8 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIM86951.1 - 7.8e-05 22.5 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EIM86951.1 - 0.00012 21.9 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase TIP49 PF06068.8 EIM86951.1 - 0.00017 20.4 0.2 0.17 10.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EIM86951.1 - 0.00041 20.0 0.9 1.5 8.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Sigma54_activ_2 PF14532.1 EIM86951.1 - 0.00076 19.5 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EIM86951.1 - 0.001 18.7 0.7 5.3 6.6 0.1 3.7 3 1 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.13 EIM86951.1 - 0.0016 18.0 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EIM86951.1 - 0.0021 18.3 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EIM86951.1 - 0.0024 17.3 6.2 1.8 7.9 0.1 4.0 3 2 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EIM86951.1 - 0.0031 17.6 0.0 0.78 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EIM86951.1 - 0.0046 16.1 0.3 0.62 9.1 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIM86951.1 - 0.0053 16.2 0.0 1.1 8.7 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EIM86951.1 - 0.0063 16.1 0.2 1 8.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EIM86951.1 - 0.0098 14.9 0.1 2.6 6.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 EIM86951.1 - 0.01 15.7 0.0 0.06 13.2 0.0 2.4 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 EIM86951.1 - 0.012 14.4 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 EIM86951.1 - 0.015 14.8 0.0 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIM86951.1 - 0.031 13.9 0.0 32 4.1 0.0 3.3 2 1 1 3 3 3 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 EIM86951.1 - 0.037 13.9 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family T2SE PF00437.15 EIM86951.1 - 0.04 12.8 0.7 2 7.2 0.2 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EIM86951.1 - 0.075 12.7 0.1 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.1 EIM86951.1 - 0.08 12.9 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EIM86951.1 - 0.095 12.3 0.4 2 8.0 0.1 2.8 2 1 1 3 3 3 0 Adenylylsulphate kinase AAA_29 PF13555.1 EIM86951.1 - 0.095 12.2 0.3 0.85 9.1 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.13 EIM86951.1 - 0.11 12.1 0.0 21 4.6 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_23 PF13476.1 EIM86951.1 - 0.12 12.6 0.7 0.43 10.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EIM86951.1 - 0.15 10.7 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EIM86951.1 - 0.21 11.1 3.5 3.7 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EIM86951.1 - 0.28 10.3 1.0 13 4.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EIM86951.1 - 0.52 9.3 1.1 6.3 5.8 0.0 2.4 2 0 0 2 2 2 0 KaiC Lipase_3 PF01764.20 EIM86952.1 - 8.9e-21 73.9 0.1 1.3e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EIM86952.1 - 0.15 11.3 0.3 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Glyco_hydro_76 PF03663.9 EIM86953.1 - 9.5e-46 156.8 21.5 1.2e-45 156.5 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EIM86953.1 - 4.8e-06 26.0 1.4 0.011 15.0 0.0 2.7 2 1 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 EIM86953.1 - 0.00012 21.2 1.7 0.0065 15.5 0.1 2.3 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.15 EIM86953.1 - 0.038 12.6 1.0 0.67 8.5 0.0 2.8 2 2 0 3 3 3 0 Glycosyl hydrolase family 47 APG17 PF04108.7 EIM86955.1 - 0.0039 16.0 0.4 0.064 12.0 0.1 1.9 1 1 1 2 2 2 2 Autophagy protein Apg17 EzrA PF06160.7 EIM86955.1 - 0.015 13.5 2.0 0.055 11.6 1.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 EIM86955.1 - 0.018 15.1 1.0 0.026 14.6 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1409 PF07197.7 EIM86955.1 - 0.048 13.7 1.7 3.1 7.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) MutS_IV PF05190.13 EIM86955.1 - 0.07 13.3 2.2 21 5.3 0.1 3.0 2 1 1 3 3 3 0 MutS family domain IV APG6 PF04111.7 EIM86955.1 - 0.074 12.0 1.5 0.11 11.5 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL25 PF01499.11 EIM86955.1 - 0.15 10.3 1.3 0.19 10.0 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Macoilin PF09726.4 EIM86955.1 - 0.17 10.1 1.1 0.25 9.5 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EIM86955.1 - 2.1 7.8 7.0 8.9 5.8 4.9 1.8 1 1 0 1 1 1 0 IncA protein Methyltransf_23 PF13489.1 EIM86956.1 - 3.4e-26 91.8 0.0 5.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM86956.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM86956.1 - 9.8e-16 57.6 0.0 2.9e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM86956.1 - 1.2e-12 48.1 0.0 2.9e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM86956.1 - 2e-12 47.6 0.0 3.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIM86956.1 - 6.3e-09 35.2 0.0 1.4e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EIM86956.1 - 7.6e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM86956.1 - 1.8e-07 31.2 0.0 3.8e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EIM86956.1 - 5.6e-07 28.5 0.0 9.5e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 EIM86956.1 - 0.00044 19.4 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EIM86956.1 - 0.0016 17.8 0.2 0.0037 16.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIM86956.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EIM86956.1 - 0.0092 15.3 0.1 0.12 11.7 0.1 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TPMT PF05724.6 EIM86956.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 EIM86956.1 - 0.033 13.5 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EIM86956.1 - 0.037 12.8 0.0 0.079 11.8 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.8 EIM86956.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EIM86956.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UBN2_2 PF14227.1 EIM86958.1 - 9.8e-07 28.3 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM86958.1 - 7.2e-05 22.5 0.0 0.00023 20.9 0.0 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EIM86958.1 - 0.067 12.6 0.1 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) NAD_binding_10 PF13460.1 EIM86959.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF659 PF04937.10 EIM86959.1 - 0.054 12.9 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) ApoLp-III PF07464.6 EIM86960.1 - 0.036 14.0 1.0 0.045 13.7 0.7 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2130 PF09903.4 EIM86960.1 - 0.042 12.5 1.1 0.054 12.2 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) ATP11 PF06644.6 EIM86960.1 - 0.06 12.8 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 ATP11 protein DDE_3 PF13358.1 EIM86964.1 - 3.9e-08 33.1 0.3 5.6e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIM86965.1 - 1.9e-29 102.3 0.0 5.4e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM86965.1 - 3.4e-08 33.3 0.0 5.1e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.10 EIM86966.1 - 0.00011 21.7 0.7 0.00021 20.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CFEM PF05730.6 EIM86967.1 - 4.6 7.1 7.7 15 5.5 0.2 2.6 2 1 1 3 3 3 0 CFEM domain HSP70 PF00012.15 EIM86968.1 - 2e-227 755.8 2.1 6e-227 754.3 1.5 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM86968.1 - 2.1e-16 59.4 0.0 3.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 EIM86968.1 - 0.011 14.5 0.8 0.32 9.7 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EIM86968.1 - 0.036 13.1 0.6 0.21 10.6 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase F-box-like PF12937.2 EIM86972.1 - 6.3e-08 32.2 0.2 1.1e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM86972.1 - 1.7e-06 27.5 3.8 3.1e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 F-box domain YhjQ PF06564.7 EIM86973.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein Ldh_1_C PF02866.13 EIM86977.1 - 0.057 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Helitron_like_N PF14214.1 EIM86978.1 - 8e-09 35.4 0.0 1e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus tRNA_Me_trans PF03054.11 EIM86978.1 - 0.061 11.8 0.2 0.084 11.4 0.2 1.1 1 0 0 1 1 1 0 tRNA methyl transferase AAA_30 PF13604.1 EIM86980.1 - 4.4e-07 29.6 0.0 1.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EIM86980.1 - 0.00016 20.7 0.7 0.00087 18.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.1 EIM86980.1 - 0.00026 20.6 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM86980.1 - 0.0088 16.1 0.1 0.079 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIM86980.1 - 0.057 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 EIM86980.1 - 0.14 12.0 0.6 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIM86980.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DDE_1 PF03184.14 EIM86983.1 - 1.7e-13 50.2 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CK1gamma_C PF12605.3 EIM86984.1 - 0.13 12.8 1.5 0.16 12.5 1.1 1.1 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal DDE_1 PF03184.14 EIM86985.1 - 2.2e-10 40.0 0.0 2.5e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Rad52_Rad22 PF04098.10 EIM86986.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein DUF1869 PF08956.5 EIM86986.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Cellulase PF00150.13 EIM86988.1 - 3.1e-48 164.4 0.1 4.6e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EIM86988.1 - 4.5e-12 45.4 9.0 4.5e-12 45.4 6.3 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.11 EIM86991.1 - 7.1e-22 77.5 30.9 7.1e-22 77.5 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIM86991.1 - 2 8.5 10.7 1.3 9.1 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) FAD_binding_3 PF01494.14 EIM86992.1 - 4.2e-72 243.1 0.0 1.3e-71 241.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM86992.1 - 3.2e-28 98.4 0.0 7.2e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EIM86992.1 - 1.2e-06 27.3 0.3 1.4e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EIM86992.1 - 4.3e-05 22.5 1.0 0.00015 20.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM86992.1 - 4.6e-05 23.3 0.2 0.00013 21.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM86992.1 - 7.8e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIM86992.1 - 0.00022 20.2 0.5 0.00037 19.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM86992.1 - 0.00032 20.6 0.0 0.0013 18.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIM86992.1 - 0.0009 18.9 0.2 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIM86992.1 - 0.0011 17.9 0.4 0.0021 16.9 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ThiF PF00899.16 EIM86992.1 - 0.0017 18.1 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 EIM86992.1 - 0.0024 18.2 0.1 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM86992.1 - 0.0062 16.6 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM86992.1 - 0.009 14.9 0.2 0.018 14.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM86992.1 - 0.014 14.4 0.4 0.022 13.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIM86992.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EIM86992.1 - 0.06 12.7 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIM86992.1 - 0.064 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EIM86992.1 - 0.065 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIM86992.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Asp PF00026.18 EIM86994.1 - 1.9e-34 119.3 2.6 3.3e-25 88.9 1.6 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM86994.1 - 5.5e-07 29.6 1.5 1.2e-06 28.5 0.7 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4646 PF15496.1 EIM86999.1 - 2.5e-25 88.9 0.0 4.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DDRGK PF09756.4 EIM86999.1 - 6.4 6.1 14.4 10 5.5 10.0 1.2 1 0 0 1 1 1 0 DDRGK domain Git3 PF11710.3 EIM87000.1 - 3.6e-08 33.2 10.9 1.1e-07 31.6 7.6 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EIM87000.1 - 0.006 15.5 8.5 0.01 14.7 5.9 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 EIM87000.1 - 0.016 14.9 1.2 0.053 13.2 0.8 1.9 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term CobW_C PF07683.9 EIM87000.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF3328 PF11807.3 EIM87001.1 - 2.3e-18 66.6 0.6 3.7e-18 66.0 0.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PARP PF00644.15 EIM87003.1 - 0.021 14.2 0.0 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain DUF4599 PF15371.1 EIM87003.1 - 0.041 13.9 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF329 PF03884.9 EIM87003.1 - 0.42 10.2 6.7 0.077 12.5 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF329) SecY PF00344.15 EIM87006.1 - 1.5e-97 326.6 10.7 1.9e-97 326.3 7.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIM87006.1 - 1.6e-19 69.0 0.2 6e-19 67.2 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Prokineticin PF06607.6 EIM87006.1 - 0.29 11.2 1.3 11 6.1 0.3 3.2 3 1 1 4 4 4 0 Prokineticin PH PF00169.24 EIM87007.1 - 0.0088 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EIM87007.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SCIMP PF15050.1 EIM87007.1 - 7.2 6.5 5.2 20 5.0 0.9 2.8 2 0 0 2 2 2 0 SCIMP protein WD40 PF00400.27 EIM87009.1 - 5.4e-16 57.7 15.5 4.8e-08 32.5 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_60s PF00428.14 EIM87010.1 - 2.1e-27 95.3 10.5 3.2e-27 94.7 7.3 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Amidase PF01425.16 EIM87011.1 - 8e-76 255.6 0.4 9.9e-76 255.3 0.3 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_4 PF01565.18 EIM87013.1 - 2.2e-28 98.4 2.8 3.4e-28 97.8 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM87013.1 - 1.3e-12 47.3 1.0 2.3e-12 46.6 0.7 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EIM87014.1 - 4.8e-28 97.3 1.0 7.2e-28 96.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM87014.1 - 2.5e-16 59.2 0.6 4.7e-16 58.4 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like TraF_2 PF13729.1 EIM87015.1 - 0.031 13.1 0.4 0.051 12.3 0.3 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein zf-MYND PF01753.13 EIM87016.1 - 2.5e-10 40.0 12.4 5.4e-10 38.9 8.6 1.6 1 0 0 1 1 1 1 MYND finger FAD_binding_4 PF01565.18 EIM87017.1 - 2.1e-25 88.7 1.1 3.3e-25 88.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM87017.1 - 1.1e-11 44.3 0.4 2.3e-11 43.4 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EIM87018.1 - 4e-27 94.8 39.1 4e-27 94.8 27.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EIM87018.1 - 0.34 11.1 3.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 Phage holin MFS_1 PF07690.11 EIM87019.1 - 3.3e-20 72.1 36.8 3.3e-20 72.1 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MaoC_dehydratas PF01575.14 EIM87020.1 - 4.5e-26 90.6 0.0 1.1e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EIM87020.1 - 3.7e-08 33.2 0.0 7.5e-06 25.7 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Hexokinase_2 PF03727.11 EIM87021.1 - 1.5e-80 269.9 0.1 2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIM87021.1 - 8.3e-66 221.2 0.1 1.2e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase YscK PF06578.7 EIM87021.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Ribosomal_L14 PF00238.14 EIM87022.1 - 8.7e-42 141.7 0.6 9.6e-42 141.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DNA_ligase_aden PF01653.13 EIM87022.1 - 0.13 11.1 0.2 0.18 10.7 0.0 1.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain MFS_1 PF07690.11 EIM87023.1 - 2.2e-54 184.5 18.7 2.9e-54 184.1 13.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EIM87023.1 - 1.4e-05 23.4 6.1 0.00028 19.0 1.5 3.4 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EIM87023.1 - 1.4e-05 23.9 7.4 1.4e-05 23.9 5.2 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter DUF1705 PF08019.7 EIM87023.1 - 0.033 13.6 6.8 3.3 7.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) DUF2512 PF10710.4 EIM87023.1 - 0.36 10.2 3.3 0.84 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Wzy_C PF04932.10 EIM87023.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.3 3 1 0 3 3 3 0 O-Antigen ligase AMP-binding PF00501.23 EIM87025.1 - 3.3e-69 233.3 0.0 4e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM87025.1 - 2.2e-13 50.9 0.1 6.8e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 EIM87026.1 - 4.8e-50 170.4 0.4 9.6e-50 169.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIM87026.1 - 6.1e-46 157.2 0.0 1e-45 156.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EIM87026.1 - 1.1e-29 103.4 0.0 2.3e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EIM87026.1 - 1e-28 100.3 0.0 3.9e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 EIM87026.1 - 5.8e-26 91.3 0.0 1.3e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EIM87026.1 - 6.3e-26 90.5 0.0 1.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 EIM87026.1 - 6.9e-18 64.8 0.0 1.9e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EIM87026.1 - 1.2e-17 64.2 0.0 4.6e-13 49.4 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Thioesterase PF00975.15 EIM87026.1 - 6.9e-12 46.0 0.0 1.9e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_11 PF08241.7 EIM87026.1 - 1.3e-08 35.2 0.0 5.6e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EIM87026.1 - 1.4e-06 27.9 0.0 0.00021 20.8 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM87026.1 - 1.6e-05 25.4 0.0 0.0011 19.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 EIM87026.1 - 0.00022 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EIM87026.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EIM87026.1 - 0.0066 15.5 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EIM87026.1 - 0.15 10.9 0.0 1.4 7.7 0.0 2.3 2 1 0 2 2 2 0 DREV methyltransferase PP-binding PF00550.20 EIM87026.1 - 0.2 11.9 1.4 0.4 10.9 0.3 2.1 2 0 0 2 2 1 0 Phosphopantetheine attachment site Methyltransf_32 PF13679.1 EIM87026.1 - 0.78 9.4 0.0 1.8 8.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sod_Fe_C PF02777.13 EIM87027.1 - 5.6e-34 116.1 0.1 9e-34 115.5 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIM87027.1 - 4.5e-31 106.9 3.5 5e-31 106.7 1.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 EIM87027.1 - 0.09 12.6 5.1 0.33 10.8 2.4 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain QueF_N PF14819.1 EIM87027.1 - 0.11 12.5 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term RTA1 PF04479.8 EIM87028.1 - 2.3e-41 141.7 1.2 2.3e-41 141.7 0.8 1.4 2 0 0 2 2 2 1 RTA1 like protein F-box-like PF12937.2 EIM87030.1 - 0.037 13.7 3.8 0.35 10.6 1.4 2.9 2 1 0 2 2 2 0 F-box-like MULE PF10551.4 EIM87032.1 - 2.1e-06 27.7 0.0 5.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM87032.1 - 4.2e-05 22.9 0.0 9.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger HeLo PF14479.1 EIM87032.1 - 0.063 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Peptidase_C14 PF00656.17 EIM87035.1 - 7e-16 58.6 0.2 8.9e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM87035.1 - 0.0031 16.7 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 CHAT domain F-box-like PF12937.2 EIM87036.1 - 3e-09 36.4 0.8 0.00019 21.0 0.2 2.8 2 0 0 2 2 2 2 F-box-like PilX_N PF14341.1 EIM87037.1 - 2.5 7.8 6.3 66 3.2 0.0 2.5 2 0 0 2 2 2 0 PilX N-terminal Glyco_hydro_92 PF07971.7 EIM87038.1 - 4e-124 415.0 0.0 5e-124 414.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF607 PF04678.8 EIM87039.1 - 4.4e-43 147.2 0.0 8.5e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF607 CCDC74_C PF14917.1 EIM87039.1 - 0.093 12.7 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal LRR_8 PF13855.1 EIM87040.1 - 1.2e-47 159.5 47.6 7.2e-15 54.4 0.5 9.3 2 2 8 11 11 11 11 Leucine rich repeat LRR_4 PF12799.2 EIM87040.1 - 2.7e-47 157.6 50.9 6e-08 32.1 0.1 12.7 8 3 3 12 12 12 8 Leucine Rich repeats (2 copies) PP2C PF00481.16 EIM87040.1 - 3.5e-41 141.2 0.0 8.3e-41 140.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EIM87040.1 - 4e-25 83.9 58.4 0.081 12.9 0.0 18.4 19 1 1 20 20 20 10 Leucine Rich Repeat Guanylate_cyc PF00211.15 EIM87040.1 - 1.5e-18 66.8 0.0 2.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EIM87040.1 - 1.8e-08 33.2 48.2 2.5 8.6 0.1 16.4 18 1 1 19 19 19 3 Leucine rich repeat LRR_5 PF13306.1 EIM87040.1 - 0.00039 20.1 0.1 16 5.2 0.0 3.9 2 1 1 3 3 3 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EIM87040.1 - 0.0039 17.1 47.9 0.13 12.3 0.0 14.4 16 1 1 17 17 17 2 Leucine Rich repeat Orbi_VP6 PF01516.11 EIM87040.1 - 0.27 10.2 0.2 0.4 9.6 0.2 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF1736 PF08409.6 EIM87041.1 - 0.12 11.9 0.3 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Med26 PF08711.6 EIM87042.1 - 1.6e-06 27.4 0.0 3.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sds3 PF08598.6 EIM87042.1 - 0.0025 17.3 1.0 0.0025 17.3 0.7 1.6 2 0 0 2 2 2 1 Sds3-like Tup_N PF08581.5 EIM87042.1 - 0.022 14.9 1.0 0.052 13.7 0.7 1.6 1 0 0 1 1 1 0 Tup N-terminal Cellulase PF00150.13 EIM87043.1 - 2.1e-12 46.8 0.0 1.7e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DSPc PF00782.15 EIM87045.1 - 6.7e-08 32.1 0.0 9.8e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM87045.1 - 2.8e-07 30.1 0.0 3.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EIM87045.1 - 1.2e-06 28.8 0.1 2.8e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EIM87045.1 - 3.9e-06 26.4 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EIM87045.1 - 5e-05 23.3 0.0 0.00016 21.7 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate MFS_1 PF07690.11 EIM87047.1 - 5.9e-30 104.1 43.5 9.6e-30 103.4 30.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GWT1 PF06423.7 EIM87048.1 - 1.7e-36 125.3 0.0 2.6e-35 121.4 0.0 2.8 1 1 0 1 1 1 1 GWT1 APH PF01636.18 EIM87050.1 - 2.7e-15 56.7 0.1 6e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIM87050.1 - 0.001 18.2 0.0 0.68 9.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EIM87050.1 - 0.0011 18.4 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EIM87050.1 - 0.0019 17.7 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EIM87050.1 - 0.0043 15.7 0.0 0.0089 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EIM87050.1 - 0.066 12.1 0.0 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase DUF4492 PF14899.1 EIM87053.1 - 0.22 11.0 0.3 0.4 10.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Pkinase PF00069.20 EIM87054.1 - 1.9e-63 214.0 0.0 3.2e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87054.1 - 4.1e-44 150.6 0.0 1.4e-43 148.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.3 EIM87054.1 - 3.2e-20 72.3 0.1 5.4e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.18 EIM87054.1 - 0.0016 18.1 0.1 0.0065 16.2 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM87054.1 - 0.0063 15.5 0.0 0.1 11.5 0.0 2.6 1 1 0 1 1 1 1 Kinase-like DUF2709 PF10915.3 EIM87054.1 - 0.25 10.3 0.0 0.52 9.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) GpcrRhopsn4 PF10192.4 EIM87055.1 - 0.0059 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF566 PF04484.7 EIM87056.1 - 8 5.8 13.9 9 5.7 9.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) F-box-like PF12937.2 EIM87059.1 - 2.1e-09 36.9 0.7 8e-09 35.0 0.5 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM87060.1 - 5.2e-10 38.8 0.5 5.2e-10 38.8 0.4 2.8 3 0 0 3 3 3 1 F-box-like Ribosomal_L28 PF00830.14 EIM87062.1 - 1.5e-20 72.7 0.5 2.5e-20 72.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family F-box-like PF12937.2 EIM87065.1 - 8e-07 28.6 5.2 5e-06 26.1 3.6 2.5 1 1 0 1 1 1 1 F-box-like RNA_Me_trans PF04252.8 EIM87066.1 - 4e-32 111.2 0.0 9.4e-32 109.9 0.0 1.6 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Ninjurin PF04923.7 EIM87067.1 - 0.11 12.2 1.7 0.6 9.8 0.1 2.5 2 0 0 2 2 2 0 Ninjurin MscL PF01741.13 EIM87068.1 - 3.1e-12 46.7 2.1 5.7e-12 45.9 1.4 1.4 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Alpha-L-AF_C PF06964.7 EIM87070.1 - 1.5e-34 119.3 1.1 3e-34 118.3 0.2 1.9 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus TIMELESS PF04821.9 EIM87071.1 - 7.8e-51 172.8 0.4 1.8e-50 171.6 0.3 1.7 1 0 0 1 1 1 1 Timeless protein RNA_pol_Rpb4 PF03874.11 EIM87071.1 - 0.94 9.4 5.9 70 3.4 0.0 4.1 3 0 0 3 3 3 0 RNA polymerase Rpb4 bZIP_1 PF00170.16 EIM87072.1 - 2.8e-05 23.9 9.0 0.0017 18.2 1.6 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIM87072.1 - 0.00016 21.4 12.4 0.0016 18.2 0.7 2.5 2 0 0 2 2 2 2 Basic region leucine zipper Shugoshin_N PF07558.6 EIM87072.1 - 0.00063 19.4 8.0 0.00064 19.3 3.1 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region GOLGA2L5 PF15070.1 EIM87072.1 - 0.0049 15.4 3.1 0.0072 14.8 2.1 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF812 PF05667.6 EIM87072.1 - 0.0059 15.1 1.0 0.01 14.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HALZ PF02183.13 EIM87072.1 - 0.058 13.1 1.8 0.13 11.9 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Herpes_UL56 PF04534.7 EIM87072.1 - 0.099 12.3 7.8 0.061 13.0 1.3 2.5 2 0 0 2 2 2 0 Herpesvirus UL56 protein Lipoprotein_20 PF13942.1 EIM87072.1 - 1.1 8.8 6.8 1.8 8.0 3.7 2.1 2 1 0 2 2 2 0 YfhG lipoprotein CSTF_C PF14304.1 EIM87072.1 - 1.5 8.1 6.2 0.24 10.7 0.9 2.3 2 1 0 2 2 2 0 Transcription termination and cleavage factor C-terminal bZIP_Maf PF03131.12 EIM87072.1 - 8.1 6.8 12.5 4.3 7.7 0.7 3.2 4 0 0 4 4 4 0 bZIP Maf transcription factor Transaldolase PF00923.14 EIM87073.1 - 3.2e-17 62.6 0.0 5.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Transaldolase Hydrolase_6 PF13344.1 EIM87074.1 - 1.3e-32 111.6 0.0 2.5e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM87074.1 - 1.1e-19 69.8 0.0 2.2e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM87074.1 - 2.2e-13 51.1 0.0 2.6e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM87074.1 - 3.4e-10 40.4 0.1 2e-05 24.8 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EIM87074.1 - 0.01 15.2 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.9 EIM87074.1 - 0.064 12.6 0.2 0.18 11.1 0.1 1.6 1 1 1 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Polysacc_synt_4 PF04669.8 EIM87076.1 - 5.6e-24 84.5 2.5 3.7e-23 81.8 1.7 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis PP_kinase PF02503.12 EIM87076.1 - 0.00085 18.8 0.5 0.00097 18.7 0.4 1.2 1 0 0 1 1 1 1 Polyphosphate kinase middle domain DUF2491 PF10679.4 EIM87076.1 - 0.049 12.6 0.8 0.06 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) FadA PF09403.5 EIM87076.1 - 3 7.8 14.6 0.43 10.5 3.5 2.3 2 0 0 2 2 2 0 Adhesion protein FadA zf-MYND PF01753.13 EIM87078.1 - 2.4e-06 27.2 10.1 2.4e-06 27.2 7.0 3.0 3 0 0 3 3 3 2 MYND finger p450 PF00067.17 EIM87079.1 - 1.2e-70 238.4 0.0 2.8e-70 237.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF1348 PF07080.6 EIM87079.1 - 0.07 12.9 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) F-box-like PF12937.2 EIM87080.1 - 1.1e-05 25.0 1.0 3e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 EIM87080.1 - 1.4e-05 23.8 0.0 0.016 13.7 0.0 3.6 1 1 3 4 4 4 2 Cytochrome P450 F-box PF00646.28 EIM87080.1 - 3.5e-05 23.3 0.9 0.00015 21.2 0.6 2.3 1 0 0 1 1 1 1 F-box domain Fibrillarin PF01269.12 EIM87080.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Aminotran_1_2 PF00155.16 EIM87081.1 - 3.2e-36 125.0 0.0 4.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF677 PF05055.7 EIM87082.1 - 0.025 13.2 0.4 0.044 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3391 PF11871.3 EIM87082.1 - 7.2 6.8 13.3 2.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) p450 PF00067.17 EIM87083.1 - 1.1e-69 235.2 0.0 3.5e-69 233.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.26 EIM87084.1 - 2.8e-08 33.6 0.2 4.9e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM87084.1 - 1.1e-05 25.4 0.2 3.7e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.4 EIM87084.1 - 0.0066 15.9 10.1 0.0066 15.9 7.0 2.6 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Spt5_N PF11942.3 EIM87084.1 - 5.1 7.7 17.0 3.8 8.1 6.4 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.7 EIM87084.1 - 8.7 5.9 21.3 3.3 7.3 8.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PIG-F PF06699.6 EIM87085.1 - 1.5e-26 93.4 5.0 3.8e-15 56.3 1.0 2.3 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F Ribosomal_L34e PF01199.13 EIM87086.1 - 1.1e-38 131.2 4.9 1.7e-38 130.7 3.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.1 EIM87086.1 - 0.016 15.4 0.3 0.036 14.3 0.2 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1428 PF07237.6 EIM87086.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EIM87086.1 - 0.19 11.3 3.5 5.6 6.7 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain NACHT PF05729.7 EIM87087.1 - 3.5e-09 36.5 0.0 9.1e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM87087.1 - 2e-05 24.6 3.7 0.00029 20.8 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 EIM87087.1 - 0.00011 21.2 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain C2 PF00168.25 EIM87087.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 C2 domain AAA_22 PF13401.1 EIM87087.1 - 0.018 15.1 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIM87087.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L34e PF01199.13 EIM87088.1 - 1.1e-13 51.1 0.3 1e-05 25.6 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L34e TPR_12 PF13424.1 EIM87089.1 - 5.5e-69 228.1 50.6 8.8e-11 41.5 1.3 13.3 6 3 7 14 14 14 12 Tetratricopeptide repeat TPR_10 PF13374.1 EIM87089.1 - 6.4e-69 226.1 69.7 1.8e-07 30.8 0.4 19.3 19 0 0 19 19 19 16 Tetratricopeptide repeat Apc5 PF12862.2 EIM87089.1 - 5.4e-29 99.8 44.5 0.0073 16.1 0.4 17.6 5 4 12 18 18 17 8 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 EIM87089.1 - 9.7e-24 81.3 25.4 0.52 10.3 0.0 17.5 18 0 0 18 18 18 6 Tetratricopeptide repeat TPR_11 PF13414.1 EIM87089.1 - 5.3e-13 48.4 55.6 0.006 16.2 0.9 10.9 6 2 5 13 13 12 8 TPR repeat DUF3856 PF12968.2 EIM87089.1 - 3e-09 36.8 24.7 0.0023 17.7 0.5 7.9 6 3 1 8 8 8 4 Domain of Unknown Function (DUF3856) NACHT PF05729.7 EIM87089.1 - 7.3e-09 35.4 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM87089.1 - 3e-05 24.1 0.1 3e-05 24.1 0.1 3.9 4 0 0 4 4 4 1 AAA ATPase domain TPR_6 PF13174.1 EIM87089.1 - 0.00022 21.4 17.2 36 5.1 0.0 10.8 11 0 0 11 11 10 0 Tetratricopeptide repeat TRP_2 PF08344.6 EIM87089.1 - 0.0017 18.2 4.9 36 4.3 0.0 7.0 7 0 0 7 7 7 0 Transient receptor ion channel II AAA_19 PF13245.1 EIM87089.1 - 0.0034 17.0 0.0 0.019 14.6 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIM87089.1 - 0.0035 17.4 0.0 0.073 13.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain MoaE PF02391.12 EIM87089.1 - 0.0036 17.1 6.1 44 3.9 0.0 6.5 6 0 0 6 6 6 0 MoaE protein AAA_18 PF13238.1 EIM87089.1 - 0.014 15.7 1.0 4.5 7.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain PPR_3 PF13812.1 EIM87089.1 - 0.091 13.0 7.5 58 4.3 0.0 6.9 6 0 0 6 6 6 0 Pentatricopeptide repeat domain Prp18 PF02840.10 EIM87089.1 - 0.22 11.3 4.1 8.8 6.1 0.1 4.3 3 2 3 6 6 6 0 Prp18 domain TPR_1 PF00515.23 EIM87089.1 - 0.34 10.5 10.8 5.6 6.7 0.0 6.9 9 0 0 9 9 6 0 Tetratricopeptide repeat Ded_cyto PF06920.8 EIM87089.1 - 1.3 8.2 3.5 29 3.8 0.0 4.8 5 1 2 7 7 7 0 Dedicator of cytokinesis F-box-like PF12937.2 EIM87092.1 - 9e-07 28.5 0.9 4.8e-06 26.1 0.6 2.4 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM87093.1 - 1.1e-08 34.7 0.1 3.7e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM87094.1 - 1e-07 31.5 0.8 6.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM87095.1 - 2.1e-05 24.1 1.4 5.8e-05 22.7 1.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM87095.1 - 0.042 13.5 2.3 13 5.6 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat Cohesin_load PF10345.4 EIM87097.1 - 0.00017 20.0 0.0 0.021 13.0 0.0 2.5 3 0 0 3 3 3 2 Cohesin loading factor F-box-like PF12937.2 EIM87099.1 - 2e-06 27.3 0.3 7.7e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF3561 PF12084.3 EIM87099.1 - 0.13 12.1 1.5 4.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) LRR_4 PF12799.2 EIM87099.1 - 0.37 10.4 2.8 2.7 7.7 0.1 3.3 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM87100.1 - 0.0012 18.5 1.4 0.002 17.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like Lipase_GDSL_2 PF13472.1 EIM87101.1 - 0.00064 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CAP59_mtransfer PF11735.3 EIM87102.1 - 3.9e-72 242.3 0.0 5.3e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 EIM87102.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein APH PF01636.18 EIM87104.1 - 7.6e-16 58.5 0.1 8.4e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM87104.1 - 0.0038 16.5 0.1 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EIM87104.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EIM87104.1 - 0.022 13.8 0.0 0.024 13.7 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EIM87104.1 - 0.061 12.4 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain DUF1289 PF06945.8 EIM87104.1 - 0.099 12.1 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Beta_helix PF13229.1 EIM87106.1 - 1e-07 31.8 8.0 2e-07 30.8 5.6 1.5 1 0 0 1 1 1 1 Right handed beta helix region B_lectin PF01453.19 EIM87106.1 - 1.4e-05 24.9 0.0 0.004 17.0 0.0 3.0 3 0 0 3 3 3 2 D-mannose binding lectin NosD PF05048.8 EIM87106.1 - 0.012 14.7 0.3 0.024 13.8 0.2 1.4 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Nop53 PF07767.6 EIM87107.1 - 1.9e-72 244.3 23.3 3.1e-72 243.7 16.2 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ScpA_ScpB PF02616.9 EIM87107.1 - 2.6 7.5 9.2 0.48 9.9 3.3 2.0 2 0 0 2 2 2 0 ScpA/B protein F-box-like PF12937.2 EIM87110.1 - 1.2e-07 31.3 4.0 2e-07 30.6 1.4 2.4 2 0 0 2 2 2 1 F-box-like DUF724 PF05266.9 EIM87110.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) F-box PF00646.28 EIM87110.1 - 0.21 11.2 6.5 22 4.8 2.9 3.6 2 1 0 2 2 2 0 F-box domain CFEM PF05730.6 EIM87111.1 - 1.6e-12 47.0 11.5 3.8e-12 45.8 8.0 1.6 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.6 EIM87111.1 - 1.1 7.2 18.2 1.2 7.1 12.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EIM87111.1 - 5.3 5.2 11.0 5.8 5.0 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 EIM87111.1 - 6.6 4.4 14.2 7.2 4.3 9.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L31e PF01198.14 EIM87112.1 - 1.4e-34 117.6 2.1 1.6e-34 117.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Nexin_C PF08628.7 EIM87112.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.6 1 1 0 1 1 1 0 Sorting nexin C terminal F-box-like PF12937.2 EIM87113.1 - 0.0009 18.9 0.4 0.0009 18.9 0.3 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EIM87113.1 - 0.024 14.2 0.2 8.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Cortexin PF11057.3 EIM87115.1 - 0.061 12.9 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Cortexin of kidney RPN7 PF10602.4 EIM87116.1 - 9.5e-40 135.8 0.1 1.4e-39 135.2 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIM87116.1 - 1.6e-15 57.2 0.2 7.9e-15 55.0 0.0 2.2 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EIM87116.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EIM87116.1 - 0.02 14.7 0.2 2.9 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM87116.1 - 0.041 13.5 0.2 8.8 6.0 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 EIM87116.1 - 0.06 13.2 0.6 5.9 6.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 EIM87117.1 - 8.7e-46 156.3 0.0 1.1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EIM87118.1 - 4.2e-55 186.9 0.0 6.1e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87118.1 - 4.6e-32 111.2 0.0 9.1e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM87118.1 - 3.8e-05 22.7 0.1 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EIM87118.1 - 8.8e-05 21.5 0.1 0.0066 15.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM87118.1 - 0.084 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM87118.1 - 0.13 10.9 0.2 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Usp PF00582.21 EIM87119.1 - 6.4e-14 52.3 0.1 9.8e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family DUF3187 PF11383.3 EIM87119.1 - 0.16 11.0 0.7 0.24 10.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) WW PF00397.21 EIM87120.1 - 2.4e-06 27.2 2.9 2.4e-06 27.2 2.0 1.9 2 0 0 2 2 2 1 WW domain HrpA_pilin PF09589.5 EIM87120.1 - 0.0013 19.1 0.4 0.033 14.6 0.3 2.7 1 1 0 1 1 1 1 HrpA pilus formation protein GMC_oxred_N PF00732.14 EIM87122.1 - 4e-56 190.3 0.0 5.9e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87122.1 - 2.4e-34 118.6 0.0 4.6e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase F-box-like PF12937.2 EIM87123.1 - 6.7e-06 25.7 1.8 1.8e-05 24.3 1.3 1.8 1 0 0 1 1 1 1 F-box-like FHA PF00498.21 EIM87124.1 - 4.8e-07 29.8 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Asp PF00026.18 EIM87125.1 - 2.5e-42 145.2 12.1 5.5e-42 144.1 8.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM87125.1 - 0.00093 19.6 4.6 0.052 14.0 0.1 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EIM87125.1 - 0.011 15.6 3.9 0.63 9.9 1.4 3.5 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM87125.1 - 0.074 12.5 0.1 0.95 8.9 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.17 EIM87127.1 - 1.1e-52 179.0 0.0 1.1e-51 175.8 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM87128.1 - 9.1e-68 228.8 0.0 3.3e-67 227.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM87129.1 - 2.7e-69 233.9 0.0 1.2e-68 231.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM87130.1 - 7e-68 229.2 0.0 2.3e-67 227.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4470 PF14737.1 EIM87131.1 - 1.4e-10 40.7 0.1 2.9e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EIM87131.1 - 1.7e-10 40.4 1.6 3.6e-10 39.3 1.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIM87131.1 - 0.0001 21.9 2.1 0.0023 17.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87131.1 - 0.0019 18.8 0.8 0.0052 17.4 0.6 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87131.1 - 0.03 13.9 2.0 0.038 13.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87131.1 - 0.25 11.3 0.8 0.6 10.0 0.5 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat O-FucT PF10250.4 EIM87132.1 - 3.8e-05 22.9 0.0 5.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HAD_2 PF13419.1 EIM87132.1 - 0.043 14.0 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Asp PF00026.18 EIM87134.1 - 8.5e-51 173.0 22.5 1.7e-50 172.0 15.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM87134.1 - 9.2e-05 22.4 10.7 0.00075 19.4 5.1 3.5 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM87134.1 - 0.0079 16.6 13.6 0.017 15.6 2.0 3.7 3 1 1 4 4 4 2 Aspartyl protease DUF3328 PF11807.3 EIM87135.1 - 5.2e-23 81.8 0.2 6.7e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Asp PF00026.18 EIM87136.1 - 2.5e-51 174.8 14.4 6.5e-51 173.4 10.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM87136.1 - 8.7e-06 25.7 5.4 0.0004 20.3 2.8 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM87136.1 - 0.0012 19.3 7.5 0.13 12.8 1.3 3.2 3 0 0 3 3 3 2 Aspartyl protease Atu4866 PF11512.3 EIM87136.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 TPR_11 PF13414.1 EIM87137.1 - 3e-12 45.9 0.6 6.1e-12 45.0 0.4 1.5 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EIM87137.1 - 3.7e-09 36.2 0.0 7.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EIM87137.1 - 8.7e-05 22.1 2.1 0.0018 18.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87137.1 - 0.00053 19.4 1.4 0.00078 18.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87137.1 - 0.00099 19.7 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat CbbQ_C PF08406.5 EIM87137.1 - 0.047 13.7 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal TPR_19 PF14559.1 EIM87137.1 - 0.19 12.1 0.6 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87137.1 - 0.21 11.5 0.2 1 9.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 EIM87138.1 - 1e-58 199.0 0.0 2.5e-58 197.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.7 EIM87139.1 - 0.13 11.9 0.2 0.13 11.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF485 F-box-like PF12937.2 EIM87140.1 - 2.1e-06 27.3 0.2 2.1e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM87140.1 - 0.59 9.9 4.5 8.8 6.1 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EIM87142.1 - 0.034 13.7 1.1 1.6 8.4 0.4 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIM87142.1 - 0.27 11.5 2.1 22 5.8 0.1 3.8 3 1 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 EIM87142.1 - 0.52 10.0 3.9 5.6 6.7 0.2 3.2 3 1 1 4 4 4 0 Leucine rich repeat Peptidase_M48 PF01435.13 EIM87143.1 - 4e-38 131.2 0.0 9.4e-38 130.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EIM87143.1 - 0.045 12.7 0.1 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Molybdopterin PF00384.17 EIM87144.1 - 5.6e-67 226.3 0.0 7.3e-66 222.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EIM87144.1 - 2.6e-19 68.1 0.1 5.9e-19 67.0 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EIM87144.1 - 2.9e-16 59.3 0.0 8.1e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 EIM87144.1 - 7.5e-12 44.8 0.1 2e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 EIM87144.1 - 8.8e-06 25.3 0.6 8.8e-06 25.3 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EIM87144.1 - 0.0018 18.0 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Chorismate_bind PF00425.13 EIM87145.1 - 0.16 11.2 0.2 0.3 10.3 0.1 1.4 1 0 0 1 1 1 0 chorismate binding enzyme p450 PF00067.17 EIM87146.1 - 4.8e-59 200.0 0.0 7.1e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Surp PF01805.15 EIM87147.1 - 0.035 13.7 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Surp module DUF601 PF04642.7 EIM87148.1 - 0.21 10.9 1.7 0.34 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF601 BTB PF00651.26 EIM87149.1 - 6.7e-15 55.0 0.1 1.5e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain HATPase_c_3 PF13589.1 EIM87149.1 - 3.6e-06 26.6 0.2 0.14 11.8 0.1 3.2 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC2_membrane PF01061.19 EIM87152.1 - 1.2e-79 266.3 50.5 1.9e-45 154.6 13.7 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIM87152.1 - 1.4e-36 125.7 0.0 6.3e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIM87152.1 - 5.5e-34 115.9 4.8 1.7e-27 95.0 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIM87152.1 - 3e-13 49.6 0.0 7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EIM87152.1 - 5.1e-08 32.5 0.0 0.005 16.2 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIM87152.1 - 1e-07 32.1 0.6 0.0023 17.9 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EIM87152.1 - 2.2e-07 31.1 0.0 0.0036 17.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIM87152.1 - 9e-07 28.2 0.0 5.4e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EIM87152.1 - 4.2e-05 23.5 0.6 0.38 10.7 0.2 3.0 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 EIM87152.1 - 7.3e-05 22.2 0.2 0.05 13.0 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIM87152.1 - 0.00015 21.2 0.7 0.051 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EIM87152.1 - 0.00017 21.2 0.1 0.35 10.5 0.2 2.8 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EIM87152.1 - 0.00058 20.1 0.0 0.98 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIM87152.1 - 0.00085 19.2 0.1 0.53 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIM87152.1 - 0.0011 18.5 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EIM87152.1 - 0.0014 18.1 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain ABC2_membrane_3 PF12698.2 EIM87152.1 - 0.0022 17.1 48.2 0.03 13.3 5.5 3.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_17 PF13207.1 EIM87152.1 - 0.0024 18.6 0.0 2.3 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EIM87152.1 - 0.0027 17.7 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIM87152.1 - 0.0032 17.4 0.0 0.78 9.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIM87152.1 - 0.0039 17.6 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EIM87152.1 - 0.0051 16.3 0.2 0.58 9.6 0.2 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EIM87152.1 - 0.0055 16.5 0.0 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EIM87152.1 - 0.0091 15.6 0.2 0.32 10.6 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EIM87152.1 - 0.0095 15.6 2.3 1.8 8.4 0.3 3.0 3 0 0 3 3 2 1 Part of AAA domain Arch_ATPase PF01637.13 EIM87152.1 - 0.016 14.9 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 EIM87152.1 - 0.037 13.0 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Septin SMC_N PF02463.14 EIM87152.1 - 0.043 13.0 0.0 1.2 8.3 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EIM87152.1 - 0.083 13.0 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIM87152.1 - 0.14 11.6 0.1 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIM87152.1 - 0.26 11.5 0.1 0.54 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EIM87152.1 - 0.67 8.9 0.0 4.3 6.2 0.0 2.1 3 0 0 3 3 2 0 AAA ATPase domain Chitin_synth_2 PF03142.10 EIM87153.1 - 9.3e-238 789.8 0.0 1.3e-237 789.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIM87153.1 - 1e-161 539.4 0.0 1.4e-161 539.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EIM87153.1 - 5.2e-18 64.5 1.8 7.2e-17 60.9 2.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EIM87153.1 - 4e-14 52.9 0.0 1.7e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIM87153.1 - 4.2e-14 52.7 4.3 1.2e-13 51.2 1.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EIM87153.1 - 5.8e-12 45.2 0.0 2.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIM87153.1 - 0.00011 21.8 0.0 0.067 12.8 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM87153.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 YwiC PF14256.1 EIM87153.1 - 4 7.5 11.5 0.067 13.2 0.9 2.6 2 0 0 2 2 2 0 YwiC-like protein SURF6 PF04935.7 EIM87154.1 - 1.8e-39 135.2 49.0 1.8e-39 135.2 34.0 2.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EIM87154.1 - 5.8e-21 74.3 5.4 5.8e-21 74.3 3.7 5.8 4 1 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 ABC_tran PF00005.22 EIM87155.1 - 7.8e-64 214.0 0.0 8.9e-32 110.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM87155.1 - 6.8e-60 202.8 29.9 1.5e-31 109.8 4.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM87155.1 - 1.9e-14 53.4 2.0 3.7e-05 23.0 0.0 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EIM87155.1 - 5.4e-10 38.4 1.6 1.1e-05 24.2 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EIM87155.1 - 2.5e-09 37.9 0.0 0.0014 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM87155.1 - 1.7e-08 33.8 2.1 0.0045 16.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM87155.1 - 1.7e-08 34.6 5.0 2.2e-05 24.5 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EIM87155.1 - 2.8e-08 34.0 0.0 0.3 10.9 0.0 4.2 3 1 1 4 4 4 1 AAA domain AAA_10 PF12846.2 EIM87155.1 - 6.6e-08 32.3 0.5 0.2 11.0 0.0 4.2 4 0 0 4 4 4 2 AAA-like domain IstB_IS21 PF01695.12 EIM87155.1 - 3.9e-07 29.6 0.3 0.82 9.0 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein DUF258 PF03193.11 EIM87155.1 - 6e-07 28.7 0.1 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIM87155.1 - 1.5e-06 28.5 0.0 0.027 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM87155.1 - 2.1e-06 27.9 0.6 0.13 12.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIM87155.1 - 1.8e-05 24.2 0.2 0.35 10.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EIM87155.1 - 3.5e-05 23.4 0.6 0.048 13.2 0.0 4.1 4 1 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EIM87155.1 - 3.9e-05 22.8 0.0 0.21 10.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EIM87155.1 - 0.00012 21.6 0.0 0.67 9.3 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EIM87155.1 - 0.00012 22.0 0.3 0.024 14.4 0.0 2.6 3 0 0 3 3 2 1 Domain of unknown function DUF87 APS_kinase PF01583.15 EIM87155.1 - 0.00064 19.4 0.2 0.93 9.1 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase CbiA PF01656.18 EIM87155.1 - 0.00073 18.9 0.1 0.07 12.5 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EIM87155.1 - 0.00097 19.5 1.2 0.27 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIM87155.1 - 0.0012 19.0 0.2 0.49 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 EIM87155.1 - 0.0018 18.1 2.0 1.4 8.8 0.3 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EIM87155.1 - 0.0018 18.1 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM87155.1 - 0.0022 17.7 0.0 4.7 6.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EIM87155.1 - 0.0065 15.2 0.1 0.19 10.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit MobB PF03205.9 EIM87155.1 - 0.0082 15.8 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EIM87155.1 - 0.012 14.1 0.0 1.9 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.1 EIM87155.1 - 0.018 13.6 0.1 1.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.13 EIM87155.1 - 0.02 14.4 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 EIM87155.1 - 0.026 13.6 0.2 7.6 5.5 0.0 2.5 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EIM87155.1 - 0.027 14.1 0.2 5.4 6.6 0.0 3.1 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.21 EIM87155.1 - 0.029 13.8 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EIM87155.1 - 0.031 14.1 0.0 9.7 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EIM87155.1 - 0.053 13.4 1.6 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EIM87155.1 - 0.057 12.9 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 EIM87155.1 - 0.058 12.3 0.9 4.3 6.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.18 EIM87155.1 - 0.061 13.2 0.0 6.6 6.7 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EIM87155.1 - 0.066 12.0 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Miro PF08477.8 EIM87155.1 - 0.089 13.2 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DEAD PF00270.24 EIM87155.1 - 0.1 12.0 0.6 1 8.8 0.0 2.7 2 2 1 3 3 3 0 DEAD/DEAH box helicase CoaE PF01121.15 EIM87155.1 - 0.12 11.7 0.2 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Pox_A32 PF04665.7 EIM87155.1 - 1.2 8.4 2.2 38 3.4 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A32 protein F-box-like PF12937.2 EIM87156.1 - 0.00013 21.5 0.8 0.00013 21.5 0.5 3.1 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EIM87156.1 - 0.0026 17.3 4.1 4.5 7.0 0.6 4.3 2 2 0 2 2 2 2 Leucine Rich repeats (2 copies) Deltaretro_Tax PF05599.6 EIM87156.1 - 0.038 14.3 0.5 0.43 10.9 0.1 2.6 1 1 1 2 2 2 0 Deltaretrovirus Tax protein LRR_8 PF13855.1 EIM87156.1 - 0.05 13.3 8.6 0.39 10.5 0.5 3.7 3 1 1 4 4 4 0 Leucine rich repeat N2227 PF07942.7 EIM87158.1 - 2.1e-92 308.9 0.0 2.7e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EIM87158.1 - 4.7e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM87158.1 - 0.012 16.0 0.0 0.052 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIM87158.1 - 0.13 12.7 0.0 0.56 10.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DUF605 PF04652.11 EIM87158.1 - 0.3 10.4 6.2 0.44 9.8 4.3 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_transf_90 PF05686.7 EIM87159.1 - 8.9e-13 47.6 0.3 1.8e-10 40.0 0.3 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 90 PTPA PF03095.10 EIM87160.1 - 2.5e-118 394.6 0.0 3.1e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FLILHELTA PF10306.4 EIM87161.1 - 8.1e-26 89.8 0.1 2e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EIM87161.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) PepSY PF03413.14 EIM87161.1 - 0.11 13.1 0.1 25 5.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain UbiA PF01040.13 EIM87162.1 - 5.3e-28 97.9 17.5 6.4e-28 97.6 12.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NAD_binding_4 PF07993.7 EIM87163.1 - 3.5e-36 124.3 0.0 5.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM87163.1 - 8.7e-32 110.0 0.0 4.1e-31 107.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM87163.1 - 5.4e-13 48.9 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM87163.1 - 0.00025 21.2 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIM87163.1 - 0.047 13.6 0.2 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EIM87163.1 - 0.13 12.3 0.1 1.2 9.1 0.1 2.3 1 1 0 1 1 1 0 NADH(P)-binding RHD3 PF05879.7 EIM87164.1 - 1.9e-06 26.1 0.0 3.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIM87164.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Isy1 PF06246.7 EIM87165.1 - 8.4e-81 271.1 0.1 1.3e-80 270.5 0.1 1.3 1 1 0 1 1 1 1 Isy1-like splicing family CENP-Q PF13094.1 EIM87165.1 - 6.9 6.6 8.1 3.5 7.6 1.3 3.1 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Conotoxin PF02950.12 EIM87166.1 - 3.9e-05 24.3 1.2 4.4e-05 24.1 0.9 1.1 1 0 0 1 1 1 1 Conotoxin Dickkopf_N PF04706.7 EIM87166.1 - 0.0042 17.2 1.6 0.0052 16.9 1.1 1.2 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Agouti PF05039.7 EIM87166.1 - 0.028 14.7 0.2 0.028 14.7 0.1 1.1 1 0 0 1 1 1 0 Agouti protein Toxin_12 PF07740.7 EIM87166.1 - 0.11 12.9 6.2 0.17 12.4 4.3 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Imm11 PF15563.1 EIM87166.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Immunity protein 11 Toxin_27 PF08099.6 EIM87166.1 - 0.31 10.9 6.1 0.5 10.2 4.3 1.3 1 0 0 1 1 1 0 Scorpion calcine family Toxin_19 PF08088.7 EIM87166.1 - 1.5 8.8 6.3 2.7 7.9 4.4 1.4 1 1 0 1 1 1 0 Conotoxin I-superfamily Toxin_23 PF08093.6 EIM87166.1 - 4.5 7.3 9.6 7.2 6.6 6.5 1.5 1 1 0 1 1 1 0 Magi 5 toxic peptide family ABC2_membrane PF01061.19 EIM87167.1 - 1e-78 263.3 46.1 1.1e-42 145.5 11.6 3.6 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIM87167.1 - 1.4e-35 122.6 0.0 4.6e-17 62.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EIM87167.1 - 2.9e-35 120.0 2.8 9.2e-28 95.9 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIM87167.1 - 2.7e-12 46.6 0.2 6.5e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EIM87167.1 - 4e-08 32.8 0.0 0.0023 17.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EIM87167.1 - 2.8e-07 29.8 0.0 1.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM87167.1 - 9.2e-07 29.0 0.0 0.011 15.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM87167.1 - 2.9e-06 27.3 0.3 0.0069 16.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain cobW PF02492.14 EIM87167.1 - 6.7e-06 25.6 0.1 0.028 13.8 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIM87167.1 - 0.00016 21.1 0.9 0.052 13.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIM87167.1 - 0.00029 21.1 0.0 0.8 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIM87167.1 - 0.00033 20.5 0.0 0.52 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EIM87167.1 - 0.00063 18.8 23.4 0.00063 18.8 16.2 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_28 PF13521.1 EIM87167.1 - 0.00072 19.5 1.0 0.8 9.6 0.2 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EIM87167.1 - 0.00087 18.9 0.1 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 EIM87167.1 - 0.00088 19.1 1.7 0.95 9.4 0.0 3.0 3 0 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIM87167.1 - 0.00094 18.6 0.1 2 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 EIM87167.1 - 0.00097 19.9 0.1 1.4 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EIM87167.1 - 0.0015 18.5 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EIM87167.1 - 0.0022 17.4 0.3 0.97 8.9 0.2 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EIM87167.1 - 0.0049 17.3 0.0 4.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EIM87167.1 - 0.0051 16.3 0.0 0.74 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EIM87167.1 - 0.0067 16.3 0.0 0.8 9.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 EIM87167.1 - 0.0075 15.3 0.0 2.6 6.9 0.1 2.2 2 0 0 2 2 2 1 Septin AAA_19 PF13245.1 EIM87167.1 - 0.0098 15.6 1.0 2.6 7.8 0.3 2.9 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 EIM87167.1 - 0.011 15.4 1.1 0.29 10.7 0.1 3.1 4 0 0 4 4 3 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EIM87167.1 - 0.013 14.7 0.0 0.33 10.1 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 EIM87167.1 - 0.045 13.9 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EIM87167.1 - 0.056 13.1 0.0 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EIM87167.1 - 0.061 13.5 0.0 9.4 6.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIM87167.1 - 0.15 10.9 0.2 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EIM87167.1 - 0.21 11.8 0.0 0.53 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain INTS5_C PF14838.1 EIM87167.1 - 0.64 8.2 0.0 1.1 7.5 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Sugar_tr PF00083.19 EIM87168.1 - 2.4e-110 369.2 27.4 2.7e-110 369.0 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM87168.1 - 6.5e-26 90.8 27.4 6.5e-26 90.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM87168.1 - 7e-07 27.8 4.0 7e-07 27.8 2.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIM87168.1 - 0.00031 19.0 5.6 0.00048 18.3 1.3 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector Cation_efflux PF01545.16 EIM87169.1 - 8.6e-11 41.4 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family SP_C-Propep PF08999.5 EIM87172.1 - 0.01 15.2 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2461 PF09365.5 EIM87173.1 - 1.7e-65 220.3 0.0 2.7e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) AMP-binding PF00501.23 EIM87174.1 - 5.1e-95 318.3 0.8 5.9e-95 318.1 0.1 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM87174.1 - 2.7e-22 79.5 0.3 2e-20 73.5 0.1 3.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 EIM87174.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Sugar_tr PF00083.19 EIM87175.1 - 1.3e-71 241.5 27.8 1.5e-71 241.3 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM87175.1 - 2.7e-26 92.1 25.1 2.7e-26 92.1 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 EIM87175.1 - 0.0099 15.3 6.6 0.0099 15.3 4.6 3.5 3 1 1 4 4 4 1 7TM receptor with intracellular HD hydrolase Amidohydro_2 PF04909.9 EIM87177.1 - 1.9e-25 89.9 0.1 2.6e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EIM87177.1 - 0.0055 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EIM87178.1 - 1.2e-111 373.0 0.0 1.6e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EIM87178.1 - 0.00013 21.0 0.1 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EIM87178.1 - 0.00025 20.2 0.0 0.37 9.8 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EIM87178.1 - 0.00026 20.0 0.1 0.00043 19.2 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIM87178.1 - 0.13 11.3 0.2 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Sugar_tr PF00083.19 EIM87179.1 - 1.7e-32 112.5 31.4 5.5e-31 107.6 21.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM87179.1 - 1e-24 86.9 37.2 8e-12 44.5 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7kD_coat PF02495.12 EIM87179.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.4 3 0 0 3 3 3 0 7kD viral coat protein G0-G1_switch_2 PF15103.1 EIM87179.1 - 0.89 9.8 2.8 3.8 7.7 0.5 2.7 2 1 0 2 2 2 0 G0/G1 switch protein 2 Peptidase_M24 PF00557.19 EIM87180.1 - 4.2e-42 144.0 0.0 5.8e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIM87180.1 - 0.003 18.0 0.0 0.0059 17.0 0.0 1.5 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Macoilin PF09726.4 EIM87181.1 - 0.011 14.0 0.2 0.01 14.1 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Zn_clus PF00172.13 EIM87181.1 - 0.095 12.6 2.8 0.16 11.9 2.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIM87181.1 - 0.6 9.9 0.0 0.6 9.9 0.0 2.6 2 1 1 3 3 3 0 PAS fold Hid1 PF12722.2 EIM87181.1 - 5.6 4.5 9.1 7 4.1 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_1 PF00232.13 EIM87182.1 - 6.4e-155 515.7 0.8 7.9e-155 515.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EIM87182.1 - 0.0013 18.2 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core GFO_IDH_MocA PF01408.17 EIM87183.1 - 1.7e-15 57.5 0.0 2.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIM87183.1 - 0.00041 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain BTB PF00651.26 EIM87184.1 - 0.013 15.4 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Sugar_tr PF00083.19 EIM87185.1 - 6.2e-107 357.9 24.5 7.7e-107 357.6 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM87185.1 - 1.5e-20 73.2 38.4 7e-17 61.1 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIM87185.1 - 0.043 11.8 5.3 0.3 9.1 0.7 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peroxidase_2 PF01328.12 EIM87186.1 - 1.4e-40 138.9 0.1 1.8e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 JAB PF01398.16 EIM87188.1 - 4e-16 58.7 0.1 5.8e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIM87188.1 - 3.3e-08 33.0 0.1 9.9e-08 31.5 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NPL4 PF05021.10 EIM87188.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 NPL4 family Pro_isomerase PF00160.16 EIM87190.1 - 1.5e-43 148.7 0.1 2.2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EIM87190.1 - 5.9e-07 29.0 1.8 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIM87190.1 - 0.012 15.5 0.3 0.25 11.3 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM87190.1 - 0.096 12.6 3.2 0.44 10.5 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87190.1 - 0.14 11.7 0.7 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP54 PF00448.17 EIM87190.1 - 0.15 11.4 1.7 0.24 10.8 1.2 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PDDEXK_2 PF12784.2 EIM87191.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Imm42 PF15601.1 EIM87192.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 42 BTB PF00651.26 EIM87193.1 - 0.00022 21.1 0.0 0.00046 20.1 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain HABP4_PAI-RBP1 PF04774.10 EIM87194.1 - 0.00038 20.9 5.1 0.00058 20.3 3.5 1.4 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF1707 PF08044.6 EIM87194.1 - 0.027 14.1 0.0 0.1 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Abhydrolase_3 PF07859.8 EIM87195.1 - 1.8e-17 63.6 0.0 4e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM87195.1 - 1.3e-12 47.1 0.0 5.7e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_2 PF02230.11 EIM87195.1 - 0.0014 18.1 0.1 0.022 14.2 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIM87195.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM87195.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.2 EIM87196.1 - 4.1e-05 23.2 1.9 4.1e-05 23.2 1.4 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM87196.1 - 0.099 12.4 1.2 3.8 7.3 0.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat Cas6 PF09559.5 EIM87197.1 - 0.0035 17.1 0.1 0.0041 16.8 0.1 1.2 1 0 0 1 1 1 1 Cas6 Crispr tRNA_anti_2 PF13742.1 EIM87197.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SCFA_trans PF02667.9 EIM87200.1 - 0.059 12.1 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter DUF3206 PF11472.3 EIM87200.1 - 0.11 12.2 0.0 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) zf-MYND PF01753.13 EIM87201.1 - 1.2e-07 31.5 18.1 2.4e-07 30.5 12.6 1.6 1 0 0 1 1 1 1 MYND finger Synapsin PF02078.11 EIM87201.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Synapsin, N-terminal domain ATP-synt_D PF01813.12 EIM87202.1 - 0.035 13.6 0.3 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 ATP synthase subunit D DUF3734 PF12536.3 EIM87202.1 - 0.17 12.0 0.7 0.29 11.2 0.5 1.3 1 0 0 1 1 1 0 Patatin phospholipase PEP-utilisers_N PF05524.8 EIM87202.1 - 0.22 11.3 1.4 0.43 10.3 1.0 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Pox_A_type_inc PF04508.7 EIM87202.1 - 9 6.3 7.8 0.8 9.6 0.2 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF202 PF02656.10 EIM87204.1 - 5.9e-08 32.8 0.6 4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1109 PF06532.6 EIM87204.1 - 0.037 13.4 3.3 0.058 12.8 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1109) Pox_I5 PF04713.7 EIM87204.1 - 0.086 12.5 1.4 7.1 6.4 0.1 2.5 2 1 0 2 2 2 0 Poxvirus protein I5 Abhydrolase_9_N PF15420.1 EIM87204.1 - 0.18 11.5 3.1 0.16 11.6 1.1 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2970 PF11174.3 EIM87204.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) GPI-anchored PF10342.4 EIM87207.1 - 8e-09 35.8 0.1 9.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidase PF01425.16 EIM87208.1 - 3e-73 247.1 0.0 6.4e-72 242.7 0.0 2.0 1 1 0 1 1 1 1 Amidase zf-C3HC4_2 PF13923.1 EIM87209.1 - 4.5e-12 45.7 19.3 2.1e-06 27.6 1.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM87209.1 - 2.1e-10 40.0 15.9 4e-06 26.3 4.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EIM87209.1 - 1e-08 34.7 13.9 1.9e-06 27.3 1.2 2.6 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_5 PF14634.1 EIM87209.1 - 7e-08 32.0 20.2 8.8e-07 28.5 6.4 2.7 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 EIM87209.1 - 8.4e-07 28.7 15.9 0.0035 17.1 5.3 2.6 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 EIM87209.1 - 2.4e-06 27.0 18.5 0.004 16.7 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM87209.1 - 0.00016 21.4 16.6 0.0071 16.2 0.9 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Atg14 PF10186.4 EIM87209.1 - 0.0035 16.3 1.2 0.0058 15.6 0.8 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_UBOX PF13445.1 EIM87209.1 - 0.012 15.2 13.5 0.42 10.3 5.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger FYVE PF01363.16 EIM87209.1 - 0.022 14.6 5.1 0.022 14.6 3.6 2.8 2 1 0 2 2 2 0 FYVE zinc finger TerY-C PF15616.1 EIM87209.1 - 0.062 13.2 9.0 0.032 14.1 2.2 2.3 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_6 PF14835.1 EIM87209.1 - 0.58 9.9 8.7 0.31 10.8 0.3 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 EIM87209.1 - 1.9 8.3 14.1 7 6.5 5.5 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 EIM87209.1 - 2.7 8.1 13.5 0.48 10.5 2.9 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Vps39_2 PF10367.4 EIM87209.1 - 3.2 7.9 15.4 0.16 12.1 2.0 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zinc-ribbons_6 PF07191.7 EIM87209.1 - 4.2 7.2 14.6 2.6 7.8 4.5 2.7 2 1 0 2 2 2 0 zinc-ribbons BTB PF00651.26 EIM87210.1 - 7.9e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1115 PF06544.7 EIM87211.1 - 0.0091 15.6 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF1115 PF06544.7 EIM87212.1 - 0.00013 21.6 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Glyco_hydro_31 PF01055.21 EIM87213.1 - 6.1e-95 318.6 1.5 7.7e-95 318.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM87213.1 - 0.00053 19.7 0.1 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Spt5-NGN PF03439.8 EIM87216.1 - 3.3e-24 84.4 0.0 7.1e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EIM87216.1 - 2.2e-11 43.0 12.7 5.4e-05 22.7 0.0 5.8 6 0 0 6 6 6 2 KOW motif CTD PF12815.2 EIM87216.1 - 4.6e-11 43.2 35.1 6.3e-10 39.5 11.8 2.9 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EIM87216.1 - 6.5e-09 36.2 13.2 6.5e-09 36.2 9.2 3.2 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 EIM87216.1 - 0.048 13.3 2.0 0.99 9.1 0.2 3.2 2 1 1 3 3 3 0 Preprotein translocase subunit SDA1 PF05285.7 EIM87216.1 - 0.19 11.0 32.9 0.33 10.1 22.8 1.3 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.2 EIM87217.1 - 8.4e-10 38.2 2.1 9e-10 38.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM87217.1 - 0.51 10.0 4.3 4.3 7.1 3.0 2.5 1 1 0 1 1 1 0 F-box domain SH3_9 PF14604.1 EIM87218.1 - 0.052 13.1 0.6 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 Variant SH3 domain UvdE PF03851.9 EIM87219.1 - 1e-91 306.8 0.0 1.3e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.19 EIM87219.1 - 0.0028 16.9 0.0 0.018 14.3 0.0 1.9 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel RhgB_N PF09284.5 EIM87220.1 - 2.9e-87 292.1 2.5 4.5e-87 291.5 1.7 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EIM87220.1 - 1.7e-46 157.8 0.1 5.7e-46 156.1 0.0 1.9 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EIM87220.1 - 2e-14 53.4 0.2 4.5e-14 52.3 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II F-box-like PF12937.2 EIM87221.1 - 5.4e-08 32.4 0.4 7.8e-08 31.9 0.3 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM87221.1 - 0.23 11.1 4.4 1.9 8.2 3.1 2.2 1 1 0 1 1 1 0 F-box domain DUF543 PF04418.7 EIM87222.1 - 2.7e-28 97.7 0.1 3e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C2HC_2 PF13913.1 EIM87222.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Hpt PF01627.18 EIM87224.1 - 3.2e-10 39.8 0.1 7.8e-10 38.6 0.1 1.7 1 1 0 1 1 1 1 Hpt domain HTH_Tnp_1 PF01527.15 EIM87224.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Transposase MSP1_C PF07462.6 EIM87224.1 - 3.8 5.7 8.5 5.5 5.2 5.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DIOX_N PF14226.1 EIM87225.1 - 5.1e-18 65.6 0.0 9.8e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM87225.1 - 3.5e-13 49.6 0.0 9e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EIM87226.1 - 1.9e-40 138.6 30.6 2.2e-39 135.1 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIM87227.1 - 2.2e-42 145.0 35.7 4.2e-42 144.1 23.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87227.1 - 3.7e-15 55.4 18.8 2.6e-10 39.4 8.2 2.8 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.1 EIM87227.1 - 6.4e-10 38.0 2.4 6.4e-10 38.0 1.7 3.5 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EIM87227.1 - 1.2e-05 23.7 4.4 1.7e-05 23.2 3.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EIM87227.1 - 1.3e-05 23.9 22.1 0.00058 18.4 1.7 3.3 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EIM87227.1 - 0.00098 17.3 5.8 0.0016 16.6 4.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 EIM87227.1 - 0.0066 16.2 1.2 0.024 14.4 0.3 2.5 2 0 0 2 2 2 1 MFS_1 like family ESSS PF10183.4 EIM87227.1 - 0.83 10.0 3.7 0.77 10.1 0.1 2.8 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1127 PF06568.6 EIM87227.1 - 5.3 6.5 12.7 0.94 8.9 2.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) PI-PLC-X PF00388.14 EIM87228.1 - 1.6e-52 176.7 0.0 2.9e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EIM87228.1 - 1.3e-40 138.0 0.1 3.4e-40 136.6 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EIM87228.1 - 2e-08 33.9 0.0 0.00091 19.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_like PF09279.6 EIM87228.1 - 0.00079 19.3 0.2 0.041 13.9 0.0 3.1 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 EIM87228.1 - 0.016 14.8 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EIM87228.1 - 0.22 11.7 0.1 0.54 10.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair DAG_kinase_N PF14513.1 EIM87228.1 - 0.23 11.6 2.7 1.5 9.0 0.0 3.4 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus MFS_1 PF07690.11 EIM87229.1 - 7e-42 143.3 32.1 7e-42 143.3 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87229.1 - 1.7e-11 43.3 10.2 1.7e-11 43.3 7.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM87229.1 - 1.7e-07 30.0 4.5 1.7e-07 30.0 3.1 3.6 3 2 2 5 5 5 2 MFS/sugar transport protein TRI12 PF06609.8 EIM87229.1 - 1.5e-06 26.7 2.1 2.2e-06 26.1 1.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIM87229.1 - 2.3e-05 22.6 4.5 3.8e-05 22.0 3.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.3 EIM87229.1 - 0.00011 20.8 12.9 0.00033 19.2 2.8 3.3 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like BT1 PF03092.11 EIM87229.1 - 0.0066 15.2 0.5 0.0066 15.2 0.3 2.1 2 0 0 2 2 2 1 BT1 family Transgly_assoc PF04226.8 EIM87229.1 - 0.0081 16.2 4.0 0.0081 16.2 2.8 2.6 2 0 0 2 2 2 1 Transglycosylase associated protein MFS_1_like PF12832.2 EIM87229.1 - 0.014 15.1 0.2 0.014 15.1 0.1 2.7 3 0 0 3 3 3 0 MFS_1 like family ESSS PF10183.4 EIM87229.1 - 0.43 11.0 1.6 2 8.8 0.0 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3096 PF11295.3 EIM87229.1 - 1.2 8.7 11.4 3.6 7.1 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) Antimicrobial17 PF08129.6 EIM87229.1 - 2.4 7.9 3.8 26 4.6 0.0 3.9 5 0 0 5 5 5 0 Alpha/beta enterocin family MFS_1 PF07690.11 EIM87230.1 - 2.1e-35 122.1 32.7 2.1e-35 122.1 22.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily COX2-transmemb PF09125.5 EIM87230.1 - 1.2 8.7 5.2 5.3 6.6 3.6 2.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Peroxidase_2 PF01328.12 EIM87232.1 - 5.2e-38 130.4 0.1 6.4e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 HupE_UreJ_2 PF13795.1 EIM87233.1 - 0.16 11.4 0.9 0.23 10.9 0.6 1.2 1 0 0 1 1 1 0 HupE / UreJ protein Seryl_tRNA_N PF02403.17 EIM87234.1 - 0.034 14.1 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EIM87234.1 - 0.081 12.6 0.4 0.16 11.6 0.2 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper F-box-like PF12937.2 EIM87235.1 - 0.00033 20.3 3.6 0.00038 20.1 0.3 2.6 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 EIM87235.1 - 0.076 13.1 0.0 22 5.5 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich repeat F-box-like_2 PF13013.1 EIM87235.1 - 3.3 7.4 5.7 19 4.9 4.0 2.5 1 1 0 1 1 1 0 F-box-like domain Peroxin-3 PF04882.7 EIM87236.1 - 9.8e-97 324.3 0.0 1.4e-96 323.9 0.0 1.2 1 0 0 1 1 1 1 Peroxin-3 But2 PF09792.4 EIM87239.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Peroxidase_2 PF01328.12 EIM87240.1 - 5.4e-39 133.7 0.1 7e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NmrA PF05368.8 EIM87241.1 - 2.9e-26 92.1 0.0 3.5e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM87241.1 - 2.5e-08 34.1 0.1 4.3e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EIM87241.1 - 2.3e-06 27.7 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIM87241.1 - 3.2e-06 26.3 0.1 5e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIM87241.1 - 4.5e-06 26.6 0.0 7.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EIM87241.1 - 4.9e-05 22.1 0.0 8e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CPSase_L_chain PF00289.17 EIM87241.1 - 0.0028 17.7 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ApbA PF02558.11 EIM87241.1 - 0.02 14.3 0.1 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EIM87241.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF2095 PF09868.4 EIM87241.1 - 0.033 13.9 0.1 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) NAD_binding_3 PF03447.11 EIM87241.1 - 0.039 14.3 0.1 6.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Viral_DNA_bi PF02236.12 EIM87241.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain GARS_N PF02844.10 EIM87241.1 - 0.16 12.4 0.3 0.41 11.1 0.0 1.8 2 0 0 2 2 1 0 Phosphoribosylglycinamide synthetase, N domain WD40 PF00400.27 EIM87242.1 - 4e-35 118.4 0.5 1.9e-09 37.0 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIM87242.1 - 3.2e-06 27.0 0.3 0.0057 16.3 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup54 PF13874.1 EIM87243.1 - 2.4e-30 105.0 1.4 4.2e-30 104.2 0.2 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EIM87243.1 - 8.5e-25 87.2 193.7 1.5e-10 41.2 31.3 4.4 1 1 3 4 4 4 4 Nucleoporin FG repeat region DUF1488 PF07369.6 EIM87243.1 - 0.066 13.0 0.5 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) SlyX PF04102.7 EIM87243.1 - 3.8 7.9 6.6 1 9.7 0.4 3.1 3 1 1 4 4 4 0 SlyX dsrm PF00035.20 EIM87244.1 - 3.8e-05 24.1 0.0 4.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif ChaC PF04752.7 EIM87244.1 - 0.082 12.8 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein Asp PF00026.18 EIM87245.1 - 5.2e-42 144.1 7.3 2.5e-41 141.9 5.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM87245.1 - 4.5e-05 23.4 1.8 0.0034 17.3 1.2 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM87245.1 - 0.0016 18.8 4.7 0.02 15.4 0.7 2.7 2 0 0 2 2 2 1 Aspartyl protease FAD_binding_4 PF01565.18 EIM87246.1 - 5.7e-19 67.9 3.7 9.6e-19 67.2 2.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM87246.1 - 9.9e-05 22.1 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Ribosomal_L27e PF01777.13 EIM87247.1 - 3.6e-35 119.9 3.6 5.3e-35 119.4 2.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIM87247.1 - 0.088 12.5 0.3 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 KOW motif SUI1 PF01253.17 EIM87247.1 - 0.16 11.7 2.8 0.41 10.4 0.5 2.4 2 1 0 2 2 2 0 Translation initiation factor SUI1 PfkB PF00294.19 EIM87248.1 - 1.6e-18 66.9 0.1 3.9e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase BTB PF00651.26 EIM87249.1 - 1.6e-06 28.0 0.0 3.5e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIM87250.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM87251.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain TFIIS_C PF01096.13 EIM87252.1 - 6.5e-13 48.0 3.1 6.5e-13 48.0 2.1 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIM87252.1 - 1.3e-08 34.3 0.9 1.3e-08 34.3 0.6 3.6 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EIM87252.1 - 0.00057 20.1 0.2 0.00057 20.1 0.1 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EIM87252.1 - 0.0026 17.9 3.3 0.27 11.5 0.7 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 EIM87252.1 - 0.021 14.6 10.7 0.24 11.2 1.6 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EIM87252.1 - 0.025 14.5 12.4 0.21 11.6 0.9 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain Elf1 PF05129.8 EIM87252.1 - 0.026 14.2 7.2 0.045 13.4 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like GFA PF04828.9 EIM87252.1 - 0.03 14.2 7.3 2.5 8.0 2.6 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-DNA_Pol PF08996.5 EIM87252.1 - 0.042 13.1 0.4 0.042 13.1 0.3 1.9 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger FYVE PF01363.16 EIM87252.1 - 0.07 13.0 5.4 2.9 7.8 0.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF2082 PF09855.4 EIM87252.1 - 0.073 12.9 4.3 4.8 7.0 0.1 3.3 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) A2L_zn_ribbon PF08792.5 EIM87252.1 - 0.079 12.4 7.2 3 7.3 0.0 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EIM87252.1 - 0.11 11.7 0.2 0.11 11.7 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.4 EIM87252.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.0 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.7 EIM87252.1 - 0.22 11.3 0.3 0.22 11.3 0.2 2.7 3 0 0 3 3 2 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.1 EIM87252.1 - 0.25 11.4 0.2 0.25 11.4 0.1 3.0 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2072 PF09845.4 EIM87252.1 - 0.51 10.2 3.3 4.8 7.1 0.0 2.6 3 0 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) PHD PF00628.24 EIM87252.1 - 0.87 9.3 9.5 0.37 10.5 0.6 2.7 2 1 0 2 2 2 0 PHD-finger DZR PF12773.2 EIM87252.1 - 1.3 8.9 12.3 5.3 6.9 1.1 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-CHY PF05495.7 EIM87252.1 - 1.3 9.2 11.1 5.5 7.2 1.2 2.7 1 1 1 2 2 2 0 CHY zinc finger DUF2318 PF10080.4 EIM87252.1 - 1.3 8.7 7.3 5.7 6.7 0.7 2.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) Zn_Tnp_IS1 PF03811.8 EIM87252.1 - 1.4 8.4 5.3 0.35 10.3 0.3 2.5 2 0 0 2 2 2 0 InsA N-terminal domain IBR PF01485.16 EIM87252.1 - 1.7 8.6 11.0 7.5 6.5 4.4 2.9 2 1 0 2 2 2 0 IBR domain Rubredoxin PF00301.15 EIM87252.1 - 1.9 8.4 4.6 30 4.5 0.0 3.7 4 0 0 4 4 4 0 Rubredoxin DUF2387 PF09526.5 EIM87252.1 - 2.1 8.3 5.9 0.43 10.5 0.3 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 EIM87252.1 - 2.3 8.2 9.6 2.8 7.9 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EIM87252.1 - 3.6 7.1 14.0 0.59 9.6 0.5 3.6 3 1 1 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EIM87252.1 - 4.8 6.7 12.1 2.7 7.5 0.9 2.8 2 2 0 2 2 2 0 Transposase zinc-binding domain zf-C2H2 PF00096.21 EIM87252.1 - 5.9 7.4 11.8 4.2 7.9 0.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-NADH-PPase PF09297.6 EIM87252.1 - 7.2 6.2 6.7 6.8 6.2 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 EIM87252.1 - 8.1 6.3 11.1 2.8e+02 1.4 7.8 3.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ifi-6-16 PF06140.8 EIM87253.1 - 0.00013 21.6 29.7 0.00013 21.6 20.6 1.8 1 1 1 2 2 2 1 Interferon-induced 6-16 family Chlam_OMP PF01308.12 EIM87253.1 - 0.19 10.2 4.0 0.25 9.8 2.8 1.0 1 0 0 1 1 1 0 Chlamydia major outer membrane protein F-box-like PF12937.2 EIM87254.1 - 2.6e-07 30.2 1.9 2.7e-06 27.0 1.3 2.4 1 1 0 1 1 1 1 F-box-like SNF5 PF04855.7 EIM87255.1 - 2.7e-73 246.4 1.1 5.4e-73 245.4 0.8 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF3133 PF11331.3 EIM87255.1 - 1.6 8.3 3.7 35 4.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DUF776 PF05604.6 EIM87256.1 - 0.12 12.5 0.3 0.13 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF776) HNH_2 PF13391.1 EIM87258.1 - 0.00013 21.6 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 EIM87259.1 - 2.9e-22 78.8 38.9 4e-22 78.3 27.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_7 PF03441.9 EIM87260.1 - 7.9e-54 182.7 0.1 1.1e-53 182.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIM87260.1 - 1.5e-20 73.5 0.0 2.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF2848 PF11010.3 EIM87266.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Abhydrolase_2 PF02230.11 EIM87268.1 - 1.4e-11 44.2 0.0 3.7e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EIM87268.1 - 0.00023 21.1 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM87268.1 - 0.0049 16.6 0.0 0.018 14.7 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 EIM87269.1 - 3.3e-86 290.1 1.4 1.1e-85 288.4 1.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM87269.1 - 0.0014 18.2 0.3 0.0074 15.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1308 PF07000.6 EIM87270.1 - 1.6e-22 79.6 0.0 1.4e-21 76.5 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF4632 PF15451.1 EIM87270.1 - 0.024 14.5 2.5 0.16 11.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) UcrQ PF02939.11 EIM87271.1 - 2.8e-20 71.9 0.3 3.2e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Peptidase_M20 PF01546.23 EIM87272.1 - 2e-23 82.8 1.2 4e-23 81.8 0.8 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87272.1 - 3.4e-09 36.4 0.0 6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM87272.1 - 0.00054 19.7 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 CRC_subunit PF08624.5 EIM87273.1 - 4.9e-40 136.6 0.0 7.4e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Abhydrolase_6 PF12697.2 EIM87275.1 - 1.9e-19 70.4 0.6 2.6e-19 70.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM87275.1 - 1.9e-05 24.3 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM87275.1 - 3.2e-05 23.7 0.0 4.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM87275.1 - 0.00023 20.4 0.0 0.001 18.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.9 EIM87275.1 - 0.0021 16.6 0.0 0.72 8.2 0.0 2.2 2 0 0 2 2 2 2 Ndr family Lipase_3 PF01764.20 EIM87275.1 - 0.005 16.4 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.8 EIM87275.1 - 0.012 13.8 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S41 PF03572.13 EIM87276.1 - 5.5e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Aldedh PF00171.17 EIM87277.1 - 3.4e-113 378.4 0.0 4.6e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 EIM87277.1 - 0.046 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated FAD_binding_3 PF01494.14 EIM87278.1 - 1.9e-74 250.8 0.0 3.6e-74 249.9 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM87278.1 - 0.00026 20.9 0.0 0.0051 16.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM87278.1 - 0.00031 21.0 0.2 0.036 14.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM87278.1 - 0.00054 18.5 0.2 0.026 13.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EIM87278.1 - 0.00069 18.6 0.1 0.028 13.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM87278.1 - 0.0013 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM87278.1 - 0.025 13.6 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EIM87278.1 - 0.046 12.5 0.4 0.081 11.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EIM87278.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM87278.1 - 0.059 11.9 0.1 7.3 5.1 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EIM87278.1 - 0.073 11.9 0.3 0.2 10.5 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein WD40 PF00400.27 EIM87279.1 - 0.068 13.0 0.1 8.7 6.4 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_S41 PF03572.13 EIM87280.1 - 0.00047 19.6 0.0 0.0015 18.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 EPL1 PF10513.4 EIM87281.1 - 4.8e-16 59.4 0.0 4.8e-16 59.4 0.0 2.6 4 0 0 4 4 4 1 Enhancer of polycomb-like Acetyltransf_3 PF13302.1 EIM87283.1 - 5e-09 36.4 0.0 6.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M20 PF01546.23 EIM87284.1 - 6.2e-22 78.0 0.0 9.8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87284.1 - 4.4e-11 42.5 0.0 1.3e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM87284.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 EIM87285.1 - 1.2e-20 73.8 0.0 2.6e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87285.1 - 2.2e-11 43.4 0.0 4.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_transf_18 PF15024.1 EIM87286.1 - 6e-11 41.3 0.0 8.4e-11 40.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 WD40 PF00400.27 EIM87287.1 - 1.1e-56 186.7 15.9 3.5e-11 42.5 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EIM87287.1 - 2.1e-11 43.3 3.1 4.7e-11 42.2 2.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM87287.1 - 6.3e-10 38.4 1.0 1.3e-09 37.4 0.7 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIM87287.1 - 8.8e-05 20.8 4.6 0.95 7.5 0.0 4.6 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIM87287.1 - 0.00057 19.4 0.0 0.081 12.3 0.0 3.0 2 1 0 2 2 2 1 PQQ-like domain UPF0139 PF03669.8 EIM87288.1 - 7.1e-07 28.6 0.0 8.2e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Acyl_transf_3 PF01757.17 EIM87288.1 - 0.014 14.2 0.1 0.015 14.1 0.1 1.0 1 0 0 1 1 1 0 Acyltransferase family SET PF00856.23 EIM87289.1 - 9.8e-28 97.4 0.1 2.8e-27 96.0 0.1 1.7 1 1 0 1 1 1 1 SET domain N-SET PF11764.3 EIM87289.1 - 0.52 10.2 2.5 0.88 9.4 1.8 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N zf-C2H2 PF00096.21 EIM87290.1 - 6.9e-05 22.9 2.6 0.00064 19.9 0.4 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM87290.1 - 9.4e-05 22.4 3.2 0.013 15.7 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger WD40 PF00400.27 EIM87291.1 - 5e-15 54.7 4.7 0.0012 18.5 0.0 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF4394 PF14339.1 EIM87291.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) Peptidase_M20 PF01546.23 EIM87292.1 - 8.7e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87292.1 - 6.3e-10 38.7 0.0 1.6e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM87292.1 - 5.1e-05 23.0 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CHAT PF12770.2 EIM87293.1 - 2.1e-34 118.9 0.0 4.2e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EIM87293.1 - 6.7e-17 60.8 12.7 0.0062 16.1 0.2 10.0 3 2 6 10 10 10 6 TPR repeat TPR_12 PF13424.1 EIM87293.1 - 1.1e-15 57.2 19.2 0.02 14.7 0.4 10.4 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.1 EIM87293.1 - 3e-06 26.5 11.7 0.6 10.0 0.0 8.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM87293.1 - 9.7e-05 22.0 10.3 2.8 8.0 0.2 9.0 9 1 0 10 10 10 1 Tetratricopeptide repeat Helitron_like_N PF14214.1 EIM87295.1 - 2.3e-12 47.0 0.0 5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DoxX_3 PF13781.1 EIM87297.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 DoxX-like family rve PF00665.21 EIM87302.1 - 0.017 15.2 0.1 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain F-box-like PF12937.2 EIM87308.1 - 1.2e-05 24.8 0.0 4.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM87308.1 - 8.5e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Thr_synth_N PF14821.1 EIM87312.1 - 9.5e-29 99.2 0.0 3.1e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EIM87312.1 - 1e-19 70.9 0.1 1.3e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2b PF00587.20 EIM87313.1 - 1.1e-33 116.3 0.0 1.6e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIM87313.1 - 1.5e-20 73.1 4.4 1.5e-20 73.1 3.1 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4196 PF13846.1 EIM87314.1 - 5 7.4 10.2 2.2 8.6 3.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) BTB PF00651.26 EIM87315.1 - 0.00043 20.2 0.0 0.001 19.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM87316.1 - 0.00019 21.3 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM87317.1 - 2.7e-05 24.0 0.2 9.8e-05 22.3 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Ribonuc_2-5A PF06479.7 EIM87319.1 - 1e-45 154.7 0.1 1.6e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EIM87319.1 - 1.8e-37 128.8 0.0 2.8e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87319.1 - 3.2e-16 59.1 0.0 1.2e-14 53.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase PQQ PF01011.16 EIM87319.1 - 0.00037 19.8 0.0 0.0023 17.3 0.0 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat DUF812 PF05667.6 EIM87320.1 - 0.0047 15.5 2.7 0.0076 14.8 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Uso1_p115_C PF04871.8 EIM87320.1 - 0.054 13.4 1.3 0.18 11.7 0.9 1.9 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.3 EIM87320.1 - 0.18 11.5 2.4 0.28 10.9 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med21 PF11221.3 EIM87320.1 - 0.46 10.4 5.4 0.44 10.5 0.7 3.3 3 0 0 3 3 3 0 Subunit 21 of Mediator complex DivIC PF04977.10 EIM87320.1 - 0.59 9.6 2.4 1.7 8.1 1.7 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF948 PF06103.6 EIM87320.1 - 0.69 9.8 0.9 6.1 6.7 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EIM87320.1 - 4 7.3 7.0 0.33 10.7 1.3 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EIM87320.1 - 8.5 5.3 6.7 2.5 7.0 2.2 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Asp PF00026.18 EIM87321.1 - 4.3e-51 174.0 6.9 5.3e-51 173.7 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM87321.1 - 0.00026 21.4 3.7 0.39 11.2 0.0 4.0 3 2 0 3 3 3 2 Aspartyl protease RVP PF00077.15 EIM87321.1 - 0.013 15.4 2.2 0.094 12.6 0.0 3.1 3 0 0 3 3 3 0 Retroviral aspartyl protease TAXi_N PF14543.1 EIM87321.1 - 0.019 14.8 2.0 0.074 12.9 0.1 2.5 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EIM87321.1 - 0.063 13.0 0.6 0.61 9.9 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease STAG PF08514.6 EIM87322.1 - 8.3e-26 90.0 0.1 3.3e-25 88.0 0.1 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EIM87322.1 - 1.3e-08 34.9 0.0 5.5e-05 23.3 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EIM87322.1 - 0.00016 21.4 3.3 9 6.6 0.1 6.1 4 1 2 6 6 6 2 HEAT repeat Pkinase PF00069.20 EIM87323.1 - 1.8e-40 138.7 0.0 2.9e-39 134.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87323.1 - 1.6e-15 56.8 0.0 3.5e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM87323.1 - 3.5e-06 26.1 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like EHN PF06441.7 EIM87325.1 - 1.3e-31 108.8 0.4 3.4e-30 104.2 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIM87325.1 - 7.8e-12 45.5 3.7 2.3e-11 44.0 2.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM87325.1 - 9.4e-08 31.8 0.2 1.2e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2183 PF09949.4 EIM87326.1 - 2.2e-29 101.2 0.0 4.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pkinase PF00069.20 EIM87327.1 - 2.3e-20 72.8 0.0 3.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87327.1 - 3.1e-10 39.5 0.0 8.7e-10 38.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM87327.1 - 1.3e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIM87327.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EIM87329.1 - 4.7e-42 143.9 0.0 6.1e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87329.1 - 3.7e-13 49.1 0.0 3.5e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM87329.1 - 0.0034 17.1 1.4 0.21 11.2 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIM87329.1 - 0.046 12.7 0.2 0.086 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG14_17 PF01101.13 EIM87329.1 - 0.19 12.4 5.5 0.69 10.6 3.8 2.0 1 0 0 1 1 1 0 HMG14 and HMG17 zf-C3HC4_3 PF13920.1 EIM87330.1 - 6.9e-07 28.8 6.8 6.9e-07 28.8 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM87330.1 - 3.6e-06 26.6 10.7 3.6e-06 26.6 7.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM87330.1 - 7.9e-06 25.7 10.4 7.9e-06 25.7 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM87330.1 - 8.2e-06 25.6 8.4 8.2e-06 25.6 5.8 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM87330.1 - 4.7e-05 23.0 8.5 4.7e-05 23.0 5.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM87330.1 - 6.1e-05 22.6 9.1 6.1e-05 22.6 6.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM87330.1 - 0.024 14.3 5.1 0.047 13.3 3.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TraK PF06586.6 EIM87330.1 - 0.043 12.9 0.3 0.066 12.3 0.2 1.2 1 0 0 1 1 1 0 TraK protein Glutaredoxin PF00462.19 EIM87330.1 - 0.16 11.9 1.4 3 7.9 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin zf-RING_6 PF14835.1 EIM87330.1 - 0.24 11.2 5.8 0.041 13.6 0.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Pkinase PF00069.20 EIM87331.1 - 2.8e-20 72.5 0.0 4.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EIM87331.1 - 3.7e-19 67.8 9.7 1.4e-08 34.3 0.2 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.17 EIM87331.1 - 4.4e-12 45.0 11.7 0.0011 18.7 0.1 6.4 6 0 0 6 6 6 4 HEAT repeat Pkinase_Tyr PF07714.12 EIM87331.1 - 2.9e-07 29.8 0.0 3.3e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EIM87331.1 - 2.9e-05 24.2 4.8 0.15 12.3 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats Cohesin_HEAT PF12765.2 EIM87331.1 - 0.044 13.7 4.4 5.1 7.1 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EIM87331.1 - 0.063 11.5 1.1 3.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 EIM87331.1 - 0.15 12.5 12.6 1.4 9.4 0.3 4.9 4 0 0 4 4 4 0 HEAT-like repeat F-box-like PF12937.2 EIM87332.1 - 1.2e-10 40.8 0.4 3.7e-10 39.3 0.3 1.9 1 0 0 1 1 1 1 F-box-like Rubredoxin PF00301.15 EIM87333.1 - 0.11 12.4 2.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin zf-NADH-PPase PF09297.6 EIM87333.1 - 0.55 9.7 0.1 0.55 9.7 0.1 2.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Prim_Zn_Ribbon PF08273.7 EIM87333.1 - 3.6 7.7 7.6 28 4.8 2.1 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase adh_short PF00106.20 EIM87334.1 - 3.5e-15 56.3 0.2 5.8e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87334.1 - 3.5e-10 39.8 0.1 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM87335.1 - 1.2e-15 57.8 0.2 1.8e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87335.1 - 1.5e-09 37.7 0.1 2.4e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 KR domain LVIVD PF08309.6 EIM87336.1 - 0.11 11.4 0.0 0.27 10.2 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat adh_short PF00106.20 EIM87337.1 - 1.5e-14 54.2 0.2 2.4e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87337.1 - 1e-07 31.7 0.2 1.6e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM87337.1 - 0.0013 18.6 0.3 0.0025 17.5 0.1 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EIM87337.1 - 0.028 13.2 0.2 0.08 11.8 0.1 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein HSP20 PF00011.16 EIM87338.1 - 9.1e-12 44.7 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family AflR PF08493.5 EIM87338.1 - 6.4 5.7 7.3 12 4.8 5.1 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein adh_short PF00106.20 EIM87339.1 - 2.1e-11 44.0 0.0 4.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87339.1 - 1.7e-06 27.8 0.1 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain APH PF01636.18 EIM87340.1 - 2.8e-16 59.9 0.1 4.4e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM87340.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EIM87340.1 - 0.046 12.8 0.0 6.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain adh_short PF00106.20 EIM87341.1 - 1.6e-12 47.7 1.1 2.6e-12 47.0 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87341.1 - 1.6e-06 27.9 0.4 2.4e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM87342.1 - 2.8e-15 56.6 0.2 4.7e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87342.1 - 7.6e-08 32.2 0.1 1.1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 KR domain tRNA-synt_2b PF00587.20 EIM87343.1 - 1.4e-43 148.4 0.1 2.2e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIM87343.1 - 1.1e-17 63.7 0.0 3.1e-17 62.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 EIM87343.1 - 1.2e-15 57.0 0.0 2.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EIM87343.1 - 1.6e-12 47.0 0.0 3.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.1 EIM87344.1 - 5.6e-24 84.0 2.5 9.4e-24 83.3 1.8 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EIM87344.1 - 3.3e-21 74.7 0.0 4.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM87344.1 - 1.1e-15 57.3 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM87344.1 - 6.7e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EIM87345.1 - 1e-15 58.0 0.4 1.9e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87345.1 - 1e-08 35.0 0.9 1.9e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIM87345.1 - 0.0033 17.2 0.1 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EIM87345.1 - 0.0099 14.8 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIM87345.1 - 0.12 12.4 0.3 0.66 10.0 0.1 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EIM87346.1 - 3.8e-12 46.4 0.1 9e-12 45.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87346.1 - 2.7e-06 27.1 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM87346.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-rbx1 PF12678.2 EIM87349.1 - 1.1e-34 118.3 13.5 1.3e-34 118.0 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIM87349.1 - 1.2e-16 60.2 9.6 1.6e-16 59.9 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EIM87349.1 - 1.7e-06 27.7 13.1 8.6e-06 25.4 9.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM87349.1 - 0.001 18.6 11.8 0.02 14.5 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM87349.1 - 0.0024 17.8 3.3 0.0024 17.8 2.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM87349.1 - 0.0037 16.8 9.9 0.37 10.5 7.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIM87349.1 - 0.15 12.0 9.3 0.74 9.8 6.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_Tnp_IS1 PF03811.8 EIM87349.1 - 0.67 9.4 0.0 0.67 9.4 0.0 2.4 4 0 0 4 4 4 0 InsA N-terminal domain zf-HC5HC2H_2 PF13832.1 EIM87349.1 - 0.74 9.8 9.5 2.6 8.0 6.5 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EIM87349.1 - 1.1 9.0 7.1 1.2 8.9 1.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EIM87349.1 - 1.1 9.0 10.8 6.8 6.4 7.5 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EIM87349.1 - 1.1 9.4 10.7 65 3.7 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TBCC PF07986.7 EIM87351.1 - 1.9e-14 53.0 2.5 6.8e-14 51.3 1.7 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C AAA_13 PF13166.1 EIM87351.1 - 0.17 10.2 0.3 0.22 9.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 EIM87352.1 - 3 7.1 5.1 3 7.1 3.5 1.0 1 0 0 1 1 1 0 Vta1 like ATP-synt PF00231.14 EIM87355.1 - 6.9e-75 252.0 7.4 7.9e-75 251.8 5.2 1.0 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.5 EIM87355.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain eIF-5_eIF-2B PF01873.12 EIM87356.1 - 3.5e-45 152.6 0.1 5.5e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIM87356.1 - 0.02 14.2 0.1 0.053 12.8 0.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.7 EIM87356.1 - 0.15 11.5 0.1 19 4.7 0.0 2.5 2 0 0 2 2 2 0 HypF finger RRM_1 PF00076.17 EIM87357.1 - 1.1e-05 24.9 0.0 0.00025 20.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM87357.1 - 9e-05 22.3 0.1 0.00027 20.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM87357.1 - 0.0046 16.7 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EIM87358.1 - 1.6e-11 43.6 31.4 0.00019 21.0 1.8 4.2 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIM87358.1 - 0.021 14.8 3.8 0.021 14.8 2.6 5.3 5 2 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EIM87358.1 - 0.56 9.8 5.1 4.4 6.9 0.1 3.3 3 0 0 3 3 3 0 LRV protein FeS4 cluster F-box-like PF12937.2 EIM87359.1 - 0.00098 18.8 0.3 0.0047 16.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like Tafi-CsgC PF10610.4 EIM87359.1 - 0.052 13.3 0.2 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein Peptidase_S41 PF03572.13 EIM87360.1 - 0.014 14.8 0.1 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 Peptidase family S41 F_bP_aldolase PF01116.15 EIM87361.1 - 8.1e-99 330.3 0.3 9.2e-99 330.1 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II F-box-like PF12937.2 EIM87362.1 - 0.00011 21.8 0.1 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM87362.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain Rubredoxin PF00301.15 EIM87362.1 - 0.43 10.4 7.6 0.29 11.0 0.5 2.4 1 1 1 2 2 2 0 Rubredoxin DUF1610 PF07754.6 EIM87362.1 - 7.6 6.7 6.7 25 5.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Thaumatin PF00314.12 EIM87365.1 - 8.7e-61 205.0 5.5 1e-60 204.8 3.8 1.0 1 0 0 1 1 1 1 Thaumatin family BRO1 PF03097.13 EIM87366.1 - 4.3e-112 374.5 0.0 1.8e-111 372.5 0.0 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIM87366.1 - 2.1e-54 184.5 12.9 4e-54 183.5 8.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1793 PF08760.6 EIM87367.1 - 3.7e-25 88.7 0.0 8.6e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EIM87367.1 - 0.0049 15.1 0.1 0.0091 14.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Serglycin PF04360.7 EIM87367.1 - 7.5 6.2 12.5 0.04 13.6 0.6 2.8 3 1 0 3 3 3 0 Serglycin DUF948 PF06103.6 EIM87368.1 - 0.019 14.8 0.3 0.87 9.4 0.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Opi1 PF08618.5 EIM87368.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 Chlorosome_CsmC PF11098.3 EIM87368.1 - 2.1 8.0 4.5 25 4.5 2.8 2.1 1 1 1 2 2 2 0 Chlorosome envelope protein C F-box-like PF12937.2 EIM87369.1 - 0.00035 20.2 0.6 0.00081 19.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM87369.1 - 0.0064 16.1 0.4 0.018 14.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain DUF1793 PF08760.6 EIM87370.1 - 4e-24 85.3 0.3 4e-24 85.3 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) FlaC_arch PF05377.6 EIM87371.1 - 0.00084 19.1 1.5 0.1 12.5 0.8 2.6 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 EIM87371.1 - 0.0023 17.8 2.0 0.0067 16.3 1.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 EIM87371.1 - 0.017 15.4 1.5 0.062 13.6 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIM87371.1 - 0.021 14.3 0.6 0.058 12.8 0.4 1.7 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.7 EIM87371.1 - 0.023 14.6 1.8 0.79 9.6 0.2 2.7 2 1 0 2 2 2 0 MbeD/MobD like bZIP_2 PF07716.10 EIM87371.1 - 0.032 14.0 3.2 0.032 14.0 2.2 2.0 2 0 0 2 2 1 0 Basic region leucine zipper ADIP PF11559.3 EIM87371.1 - 0.06 13.2 3.2 0.94 9.3 0.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIM87371.1 - 0.061 13.6 4.8 0.36 11.2 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1875 PF08961.5 EIM87371.1 - 0.11 11.7 0.2 0.11 11.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) MAD PF05557.8 EIM87371.1 - 0.28 9.2 6.8 0.056 11.5 1.0 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein HALZ PF02183.13 EIM87371.1 - 0.51 10.1 3.0 0.34 10.6 0.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper CASP_C PF08172.7 EIM87371.1 - 0.77 8.7 5.7 0.12 11.3 1.3 1.5 2 0 0 2 2 2 0 CASP C terminal TMF_TATA_bd PF12325.3 EIM87371.1 - 0.83 9.3 7.3 5.1 6.8 0.4 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.2 EIM87371.1 - 1.1 9.0 7.5 1.9 8.3 1.1 2.6 2 1 0 2 2 2 0 Tropomyosin like GAS PF13851.1 EIM87371.1 - 1.4 8.0 5.1 1.3 8.2 0.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIM87371.1 - 2.1 8.2 9.6 0.7 9.7 2.9 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 EIM87371.1 - 2.3 8.1 7.0 10 6.0 2.1 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion F-box-like PF12937.2 EIM87374.1 - 5.3e-09 35.6 0.1 1.5e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM87374.1 - 0.001 18.6 4.6 0.013 15.1 0.0 4.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EIM87374.1 - 0.086 12.5 1.9 0.32 10.7 0.5 2.6 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 EIM87374.1 - 0.15 11.7 5.1 0.75 9.5 0.0 4.0 3 1 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EIM87374.1 - 0.19 11.8 7.5 2.9 8.2 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat DUF1793 PF08760.6 EIM87375.1 - 1.9e-24 86.4 0.0 4.8e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 EIM87375.1 - 6.2e-05 22.2 0.1 0.00013 21.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4328 PF14219.1 EIM87375.1 - 0.043 13.1 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Glyco_hydro_28 PF00295.12 EIM87376.1 - 2.6e-40 138.3 6.1 7.3e-39 133.6 4.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Sds3 PF08598.6 EIM87377.1 - 1.1e-16 61.0 2.7 1.1e-16 61.0 1.9 3.3 3 0 0 3 3 3 1 Sds3-like API5 PF05918.6 EIM87377.1 - 8.8 4.6 2.8 14 4.0 2.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NUDIX PF00293.23 EIM87378.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Yip1 PF04893.12 EIM87379.1 - 2.6e-08 33.5 21.1 3.2e-08 33.2 14.7 1.2 1 0 0 1 1 1 1 Yip1 domain ThiF PF00899.16 EIM87380.1 - 2.6e-34 117.9 0.3 4.1e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EIM87380.1 - 0.012 15.8 0.1 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EIM87380.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIM87380.1 - 0.02 13.8 0.3 0.034 13.1 0.2 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 EIM87380.1 - 0.061 12.3 0.1 0.099 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EIM87380.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peroxidase_2 PF01328.12 EIM87381.1 - 1.3e-18 66.7 0.0 2.7e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 TauD PF02668.11 EIM87382.1 - 1.9e-44 152.2 0.1 2.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.20 EIM87384.1 - 6.2e-71 238.5 0.0 7.6e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87384.1 - 2.3e-32 112.1 0.0 3.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM87384.1 - 0.00029 19.9 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM87384.1 - 0.00034 19.7 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM87384.1 - 0.0013 18.5 0.0 0.0063 16.2 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIM87384.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acetyltransf_1 PF00583.19 EIM87385.1 - 6.4e-06 26.1 0.1 1.2e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM87385.1 - 2.2e-05 24.5 0.2 0.011 15.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM87385.1 - 0.0059 16.7 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EIM87385.1 - 0.0072 15.9 0.2 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EIM87385.1 - 0.034 13.4 0.0 0.085 12.1 0.0 1.7 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Acetyltransf_9 PF13527.1 EIM87385.1 - 0.063 13.1 0.2 2.4 8.0 0.0 2.6 1 1 2 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM87385.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NAD_binding_6 PF08030.7 EIM87386.1 - 3.5e-37 127.7 0.0 5.7e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM87386.1 - 7.3e-24 83.6 0.0 2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIM87386.1 - 4.9e-15 55.7 8.4 4.9e-15 55.7 5.8 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIM87386.1 - 0.00079 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIM87386.1 - 0.14 12.6 0.0 1.5 9.4 0.0 2.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DLH PF01738.13 EIM87387.1 - 2.1e-24 86.0 0.0 3.3e-24 85.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM87387.1 - 3.6e-09 36.5 0.0 6.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM87387.1 - 3.6e-06 27.0 0.0 2.3e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM87387.1 - 0.00089 18.8 0.0 0.034 13.7 0.0 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIM87387.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldo_ket_red PF00248.16 EIM87388.1 - 5.6e-50 169.7 0.0 6.3e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EIM87389.1 - 9.6e-23 80.3 0.1 1.9e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM87389.1 - 0.00037 20.3 14.4 0.00064 19.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TB2_DP1_HVA22 PF03134.14 EIM87390.1 - 0.0054 16.4 0.6 0.013 15.2 0.4 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NACHT PF05729.7 EIM87391.1 - 1e-11 44.8 0.1 2.9e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIM87391.1 - 0.00043 20.3 0.5 0.006 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM87391.1 - 0.0014 18.7 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain BrkDBD PF09607.5 EIM87391.1 - 0.081 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Ank_2 PF12796.2 EIM87392.1 - 6.4e-29 100.1 3.5 1.1e-17 64.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM87392.1 - 7.3e-20 69.7 9.2 3e-07 29.9 0.4 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EIM87392.1 - 1.3e-17 63.4 2.2 9.7e-08 32.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM87392.1 - 3.7e-15 55.9 3.6 3.5e-07 30.5 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM87392.1 - 1e-12 46.9 0.9 0.002 18.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF892 PF05974.7 EIM87392.1 - 0.0001 22.1 0.8 3.4 7.4 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF892) Spidroin_MaSp PF11260.3 EIM87392.1 - 0.0024 17.9 0.4 7.7 6.6 0.0 3.1 3 0 0 3 3 3 1 Major ampullate spidroin 1 and 2 DUF4625 PF15418.1 EIM87392.1 - 0.023 14.8 0.4 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) P19Arf_N PF07392.7 EIM87392.1 - 0.027 14.6 0.2 23 5.2 0.0 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus CholecysA-Rec_N PF09193.5 EIM87392.1 - 0.032 14.1 0.6 1e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal DUF2436 PF10365.4 EIM87392.1 - 0.043 13.4 0.3 4.4 6.9 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2436) TNV_CP PF03898.8 EIM87392.1 - 0.047 12.7 2.7 1.5 7.8 0.3 2.5 1 1 2 3 3 3 0 Satellite tobacco necrosis virus coat protein eIF-5a PF01287.15 EIM87392.1 - 0.07 13.0 0.0 3.5 7.6 0.0 2.5 1 1 2 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Fer2_4 PF13510.1 EIM87392.1 - 0.16 11.7 3.1 2 8.2 0.4 3.2 1 1 2 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF1843 PF08898.5 EIM87392.1 - 0.54 10.3 8.6 4.4 7.4 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) TB2_DP1_HVA22 PF03134.14 EIM87393.1 - 2.8e-27 94.2 4.5 3.9e-27 93.8 3.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Grp1_Fun34_YaaH PF01184.14 EIM87394.1 - 2.5e-31 108.6 21.2 3.4e-31 108.1 14.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_hydro_43 PF04616.9 EIM87395.1 - 2.1e-16 59.8 7.2 3e-14 52.7 1.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Secretin_N_2 PF07655.8 EIM87396.1 - 0.098 13.0 0.5 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain BAH PF01426.13 EIM87398.1 - 0.005 16.5 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain Toxin_8 PF07365.7 EIM87398.1 - 0.087 12.8 0.7 0.29 11.1 0.5 1.9 1 0 0 1 1 1 0 Alpha conotoxin precursor DUF2225 PF09986.4 EIM87398.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PHD PF00628.24 EIM87398.1 - 0.67 9.6 9.6 1.3 8.8 3.3 3.0 3 0 0 3 3 3 0 PHD-finger PHD PF00628.24 EIM87399.1 - 4.9e-05 22.9 2.7 0.00049 19.7 0.9 2.4 2 0 0 2 2 2 1 PHD-finger BAH PF01426.13 EIM87399.1 - 0.001 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 BAH domain Thaumatin PF00314.12 EIM87400.1 - 1e-61 208.0 11.5 1.2e-61 207.8 8.0 1.1 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.16 EIM87400.1 - 0.057 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Exo_endo_phos PF03372.18 EIM87401.1 - 1.3e-11 44.9 0.5 1.6e-11 44.6 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIM87401.1 - 0.0084 15.7 0.0 0.045 13.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Velvet PF11754.3 EIM87402.1 - 5.4e-33 114.3 0.0 8.4e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Glucan_synthase PF02364.10 EIM87404.1 - 0 1373.0 0.1 0 1372.6 0.1 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIM87404.1 - 8.9e-39 132.0 0.1 2.1e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MULE PF10551.4 EIM87406.1 - 1.4e-06 28.3 0.0 4.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM87406.1 - 2.1e-06 27.0 0.3 4.5e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger DUF863 PF05904.6 EIM87407.1 - 0.0081 14.5 0.1 0.0099 14.2 0.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF863) LIN37 PF15306.1 EIM87407.1 - 0.15 12.0 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 LIN37 DUF4608 PF15381.1 EIM87407.1 - 0.16 12.1 1.3 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) DEAD PF00270.24 EIM87410.1 - 6.4e-12 45.2 0.0 8.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fungal_trans PF04082.13 EIM87411.1 - 1.4e-16 60.1 0.1 2.5e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM87411.1 - 0.0041 16.9 14.2 0.0041 16.9 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAH PF01426.13 EIM87412.1 - 0.0038 16.9 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain DUF3182 PF11379.3 EIM87412.1 - 0.082 11.5 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Pkinase PF00069.20 EIM87413.1 - 0.00088 18.4 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EIM87413.1 - 0.00089 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIM87413.1 - 0.018 14.0 0.1 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM87413.1 - 0.03 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3721 PF12518.3 EIM87413.1 - 0.7 9.5 3.7 0.34 10.5 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function GST_N_3 PF13417.1 EIM87414.1 - 1.2e-12 47.8 0.1 3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM87414.1 - 5.3e-08 32.7 0.0 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM87414.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM87414.1 - 0.00038 20.2 0.0 0.00096 18.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM87414.1 - 0.0017 18.7 0.1 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Vps26 PF03643.10 EIM87416.1 - 2.9e-130 432.9 2.3 3.3e-130 432.7 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EIM87416.1 - 0.0025 17.6 2.2 1.1 9.0 0.0 3.5 2 1 3 5 5 5 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIM87416.1 - 0.042 13.9 0.1 0.64 10.1 0.1 2.8 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain AAA_5 PF07728.9 EIM87417.1 - 4.3e-65 217.6 0.0 2.9e-28 98.3 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 EIM87417.1 - 1.3e-05 25.3 0.0 3.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EIM87417.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIM87417.1 - 0.017 14.9 0.2 0.054 13.3 0.1 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA_22 PF13401.1 EIM87417.1 - 0.021 14.9 0.1 0.14 12.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EIM87417.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIM87417.1 - 0.26 11.2 3.3 6.3 6.7 0.0 4.0 4 1 1 5 5 5 0 AAA ATPase domain Glyco_hydro_28 PF00295.12 EIM87418.1 - 2.8e-58 197.4 16.0 3.6e-58 197.0 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM87418.1 - 6.2e-08 32.5 30.0 7.3e-08 32.3 17.3 3.0 2 1 1 3 3 3 1 Right handed beta helix region DUF1565 PF07602.6 EIM87418.1 - 6.1e-06 25.5 8.1 1.2e-05 24.6 5.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) NosD PF05048.8 EIM87418.1 - 7.3e-05 22.0 14.9 0.0002 20.5 10.0 1.9 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF2013 PF09431.5 EIM87419.1 - 3.1e-43 146.9 0.7 1.1e-42 145.0 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) VIT1 PF01988.14 EIM87420.1 - 5.7e-70 235.1 7.6 6.6e-70 234.8 5.2 1.0 1 0 0 1 1 1 1 VIT family Acetyltransf_7 PF13508.1 EIM87421.1 - 5.2e-07 29.7 0.0 9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM87421.1 - 1.9e-05 24.5 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM87421.1 - 6.1e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIM87421.1 - 0.075 12.9 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_8 PF08022.7 EIM87422.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain APOC4 PF15119.1 EIM87423.1 - 0.0058 16.5 0.3 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Apolipoprotein C4 FAD_binding_8 PF08022.7 EIM87423.1 - 0.012 15.5 0.1 0.23 11.3 0.0 2.2 1 1 1 2 2 2 0 FAD-binding domain Plus-3 PF03126.13 EIM87424.1 - 3.6e-22 78.4 0.0 1.8e-21 76.1 0.0 2.3 3 0 0 3 3 3 1 Plus-3 domain WD40 PF00400.27 EIM87425.1 - 5.4e-29 98.9 12.1 5.4e-10 38.7 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EIM87425.1 - 4.7e-26 90.6 9.8 1.1e-25 89.4 6.8 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EIM87425.1 - 0.00057 19.6 0.1 0.0083 15.8 0.0 2.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BAH PF01426.13 EIM87426.1 - 1.9e-16 59.9 1.0 2e-07 30.8 0.1 2.3 2 0 0 2 2 2 2 BAH domain PHD PF00628.24 EIM87426.1 - 0.038 13.6 2.6 0.11 12.2 0.7 2.5 2 0 0 2 2 2 0 PHD-finger BTB PF00651.26 EIM87427.1 - 1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CLN3 PF02487.12 EIM87428.1 - 3.9e-63 213.6 0.2 6.9e-61 206.2 0.1 2.1 1 1 0 1 1 1 1 CLN3 protein PNP_UDP_1 PF01048.15 EIM87429.1 - 8.6e-37 126.3 0.4 1.1e-36 126.0 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Iso_dh PF00180.15 EIM87431.1 - 3.2e-71 240.0 0.0 3.8e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.20 EIM87432.1 - 7.8e-26 90.9 0.1 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87432.1 - 2.2e-12 47.2 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87432.1 - 1.7e-11 44.1 0.1 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87432.1 - 0.025 14.3 0.1 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EIM87433.1 - 1.1e-25 90.4 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87433.1 - 2.4e-13 50.4 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87433.1 - 7.7e-11 41.9 0.1 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87433.1 - 0.006 16.3 1.3 0.013 15.2 0.1 2.2 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EIM87434.1 - 3e-25 89.0 0.1 4.4e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87434.1 - 2.8e-14 53.5 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87434.1 - 4.4e-11 42.7 0.1 6.7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87434.1 - 0.0056 16.4 0.7 0.018 14.7 0.4 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM87434.1 - 0.046 13.1 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 EIM87435.1 - 2.8e-15 56.1 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HAD_2 PF13419.1 EIM87435.1 - 0.013 15.7 0.0 0.077 13.2 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 EIM87436.1 - 2.2e-14 52.8 4.2 1.3e-10 40.8 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIM87436.1 - 5.1e-05 23.1 7.5 0.012 15.5 0.7 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87436.1 - 0.00028 20.3 10.8 0.53 9.9 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87436.1 - 0.00039 21.0 6.5 0.016 15.8 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM87436.1 - 0.00056 19.6 13.1 0.11 12.4 1.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM87436.1 - 0.02 15.0 2.3 0.047 13.8 1.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM87436.1 - 0.035 13.8 10.8 1.3 8.9 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TipAS PF07739.8 EIM87436.1 - 0.045 14.0 0.3 0.097 12.9 0.2 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain TPR_14 PF13428.1 EIM87436.1 - 0.12 13.1 4.0 3.6 8.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM87436.1 - 0.41 10.5 3.4 0.84 9.5 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM87436.1 - 9 7.0 8.0 11 6.7 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Dynamin_N PF00350.18 EIM87437.1 - 2.1e-13 50.4 0.0 1.3e-12 47.8 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIM87437.1 - 2e-05 24.4 0.0 0.002 18.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM87437.1 - 0.00011 21.4 0.0 0.00085 18.5 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIM87437.1 - 0.00093 19.5 0.0 0.008 16.4 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EIM87437.1 - 0.0035 17.3 0.9 0.02 14.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EIM87437.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain SopA PF13981.1 EIM87437.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 SopA-like central domain Adeno_IVa2 PF02456.10 EIM87437.1 - 0.027 13.1 0.0 0.049 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_10 PF12846.2 EIM87437.1 - 0.04 13.3 0.1 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EIM87437.1 - 0.074 13.1 0.1 1.1 9.4 0.0 2.9 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.8 EIM87437.1 - 0.091 11.6 0.8 0.43 9.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIM87437.1 - 0.18 12.6 4.6 0.38 11.5 0.0 3.5 4 1 0 4 4 4 0 AAA domain AAA_21 PF13304.1 EIM87437.1 - 0.28 11.0 0.2 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain SAP PF02037.22 EIM87439.1 - 2.4e-05 23.7 1.2 4.5e-05 22.8 0.3 1.9 2 0 0 2 2 2 1 SAP domain GMC_oxred_N PF00732.14 EIM87440.1 - 2.4e-64 217.3 0.0 3e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87440.1 - 1.4e-36 125.9 0.0 2.3e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM87440.1 - 1.6e-05 23.9 0.0 3.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM87440.1 - 0.00015 20.7 0.0 0.0075 15.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIM87440.1 - 0.0011 18.8 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM87440.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM87440.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM87440.1 - 0.037 12.5 0.0 0.059 11.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EIM87440.1 - 0.098 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.26 EIM87441.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain PhnA_Zn_Ribbon PF08274.7 EIM87441.1 - 0.0045 16.7 0.3 2.4 7.9 0.1 2.5 2 0 0 2 2 2 2 PhnA Zinc-Ribbon Peptidase_C48 PF02902.14 EIM87442.1 - 7.8e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AP_endonuc_2_N PF07582.7 EIM87442.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus ABC_membrane PF00664.18 EIM87444.1 - 6.2e-89 298.0 25.3 5.9e-45 153.8 8.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM87444.1 - 6.6e-68 227.2 0.0 2.8e-33 115.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EIM87444.1 - 1.2e-13 50.8 1.1 0.00017 20.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM87444.1 - 1.7e-13 51.1 0.0 0.00073 19.5 0.0 4.3 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EIM87444.1 - 1.9e-09 36.6 0.0 0.00034 19.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EIM87444.1 - 6e-08 32.8 0.1 0.0022 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM87444.1 - 9.9e-08 31.3 0.2 0.0031 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIM87444.1 - 8.3e-07 29.8 0.0 0.049 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIM87444.1 - 6.8e-06 25.3 0.0 0.085 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM87444.1 - 5.5e-05 23.3 4.5 0.49 10.5 0.2 4.5 3 2 0 3 3 3 2 AAA domain G-alpha PF00503.15 EIM87444.1 - 8.3e-05 21.4 0.0 0.23 10.1 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_25 PF13481.1 EIM87444.1 - 0.00015 21.2 0.3 0.66 9.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EIM87444.1 - 0.00022 21.5 0.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIM87444.1 - 0.00042 20.2 0.1 1.8 8.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EIM87444.1 - 0.00056 20.2 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIM87444.1 - 0.00085 19.0 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EIM87444.1 - 0.0013 18.6 1.6 1.3 8.9 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EIM87444.1 - 0.0016 18.4 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM87444.1 - 0.0033 16.5 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EIM87444.1 - 0.0039 17.0 0.0 3.8 7.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EIM87444.1 - 0.0063 16.0 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EIM87444.1 - 0.0068 16.1 0.0 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIM87444.1 - 0.011 15.7 0.0 7.4 6.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EIM87444.1 - 0.011 16.2 0.0 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_10 PF12846.2 EIM87444.1 - 0.014 14.8 0.0 9.2 5.5 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 EIM87444.1 - 0.017 15.2 0.1 2.7 8.2 0.0 3.2 3 0 0 3 3 2 0 RNA helicase DUF815 PF05673.8 EIM87444.1 - 0.021 13.7 0.0 5.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 EIM87444.1 - 0.024 13.7 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 EIM87444.1 - 0.024 14.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 EIM87444.1 - 0.042 13.3 0.0 7.3 6.0 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3987 PF13148.1 EIM87444.1 - 0.059 11.9 0.6 1 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) NB-ARC PF00931.17 EIM87444.1 - 0.062 12.1 0.0 5.4 5.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EIM87444.1 - 0.081 12.5 0.2 15 5.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.10 EIM87444.1 - 0.3 9.7 0.0 0.96 8.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DAO PF01266.19 EIM87445.1 - 1.7e-50 171.9 0.6 2.6e-50 171.3 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM87445.1 - 0.0021 17.9 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM87445.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM87445.1 - 0.0095 16.3 0.1 0.04 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM87445.1 - 0.033 13.2 0.1 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 EIM87445.1 - 0.048 13.1 0.1 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIM87445.1 - 0.11 11.0 0.0 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIY-YIG PF01541.19 EIM87447.1 - 2.4e-06 27.7 0.0 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 EIM87447.1 - 0.00028 20.6 5.1 0.0005 19.8 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EIM87447.1 - 0.00061 19.6 2.0 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.6 EIM87447.1 - 0.0027 17.6 2.5 0.026 14.5 1.8 2.4 1 1 1 2 2 2 1 RING-like domain RRN7 PF11781.3 EIM87447.1 - 0.23 10.9 2.0 30 4.2 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short_C2 PF13561.1 EIM87448.1 - 5.4e-25 88.5 0.0 6.7e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM87448.1 - 6.7e-25 87.9 0.3 4e-24 85.3 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87448.1 - 2.4e-09 37.1 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM87448.1 - 0.0017 18.3 0.1 0.0038 17.2 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EIM87448.1 - 0.0094 16.0 0.1 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EIM87448.1 - 0.014 14.2 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_Gly3P_dh_N PF01210.18 EIM87448.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EIM87448.1 - 0.041 13.5 0.2 0.076 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIM87448.1 - 0.051 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EIM87448.1 - 0.12 11.7 0.1 0.48 9.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 EIM87448.1 - 0.25 11.7 0.2 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.24 EIM87449.1 - 6.5e-45 152.6 0.0 1.4e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIM87449.1 - 7.3e-24 83.0 0.1 1.6e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIM87449.1 - 8e-20 70.4 0.0 2.5e-19 68.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIM87449.1 - 0.018 15.0 0.4 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain DUF917 PF06032.7 EIM87449.1 - 0.13 10.7 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Vfa1 PF08432.5 EIM87449.1 - 2.1 8.3 20.6 0.55 10.2 4.4 2.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 EIM87449.1 - 3.9 6.9 23.7 5.6 6.4 7.9 2.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF4407 PF14362.1 EIM87449.1 - 9.6 5.0 8.9 3.5 6.5 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SUR7 PF06687.7 EIM87450.1 - 5.1e-22 78.4 18.0 5.1e-22 78.4 12.5 1.7 1 1 1 2 2 2 1 SUR7/PalI family PAG PF15347.1 EIM87450.1 - 0.031 13.3 0.1 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched MRAP PF15183.1 EIM87450.1 - 0.062 12.9 0.6 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Herpes_gE PF02480.11 EIM87450.1 - 0.14 10.4 0.0 0.28 9.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RCR PF12273.3 EIM87450.1 - 0.16 12.5 0.4 0.16 12.5 0.3 2.4 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF2615 PF11027.3 EIM87450.1 - 0.28 11.1 1.6 0.63 9.9 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2615) Claudin_2 PF13903.1 EIM87450.1 - 2 8.0 23.6 0.22 11.2 10.2 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3784 PF12650.2 EIM87450.1 - 3.5 7.6 13.9 0.1 12.5 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) zf-DHHC PF01529.15 EIM87450.1 - 8.8 5.6 12.5 0.61 9.4 2.0 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Dynamin_N PF00350.18 EIM87451.1 - 5.2e-06 26.3 0.1 4e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EIM87451.1 - 0.044 12.5 2.9 0.21 10.3 0.7 2.3 2 0 0 2 2 2 0 Dynamin central region YGGT PF02325.12 EIM87453.1 - 0.047 13.6 1.1 0.084 12.8 0.7 1.3 1 0 0 1 1 1 0 YGGT family DUF2208 PF09973.4 EIM87453.1 - 0.076 12.2 0.1 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Rcd1 PF04078.8 EIM87453.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like CBM_1 PF00734.13 EIM87454.1 - 3.2e-10 39.4 11.2 3.2e-10 39.4 7.7 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 EIM87454.1 - 0.25 9.8 0.1 0.38 9.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RVP_2 PF08284.6 EIM87455.1 - 0.047 13.6 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease adh_short PF00106.20 EIM87456.1 - 1.1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87456.1 - 6.3e-12 45.7 0.0 8.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87456.1 - 4.5e-10 39.4 0.0 6.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87456.1 - 0.0069 16.1 0.2 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EIM87457.1 - 2.4e-24 86.1 0.0 3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87457.1 - 1.3e-12 48.0 0.0 1.8e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87457.1 - 2.5e-10 40.3 0.1 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87457.1 - 0.0016 18.1 1.1 0.0034 17.1 0.4 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM87457.1 - 0.012 15.0 0.0 0.071 12.5 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family APH PF01636.18 EIM87459.1 - 3.7e-05 23.5 1.3 0.0012 18.6 0.9 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM87459.1 - 0.00093 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Peptidase_S21 PF00716.12 EIM87460.1 - 0.17 11.1 6.6 0.21 10.8 4.6 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF605 PF04652.11 EIM87460.1 - 6.3 6.0 13.5 8.1 5.7 9.4 1.1 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EIM87461.1 - 7.5e-25 87.7 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87461.1 - 6.3e-13 49.0 0.0 8.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87461.1 - 1.5e-09 37.8 0.0 2.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87461.1 - 0.045 13.5 0.4 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM87461.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family IBR PF01485.16 EIM87462.1 - 8.8e-14 51.1 30.2 5.3e-08 32.6 2.6 3.6 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EIM87462.1 - 1.4e-07 31.4 3.0 1.4e-07 31.4 2.1 4.2 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM87462.1 - 7e-07 29.0 5.5 7e-07 29.0 3.8 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM87462.1 - 7.3e-06 25.6 2.1 7.3e-06 25.6 1.5 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EIM87462.1 - 1.4e-05 24.7 6.0 1.4e-05 24.7 4.2 3.9 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIM87462.1 - 2.3e-05 23.9 2.4 2.3e-05 23.9 1.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM87462.1 - 0.0004 19.9 5.6 0.0004 19.9 3.9 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EIM87462.1 - 0.0011 18.6 1.0 0.0029 17.2 0.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EIM87462.1 - 0.0047 16.6 4.5 0.0047 16.6 3.1 3.8 2 1 1 3 3 1 1 zinc-RING finger domain RRM_5 PF13893.1 EIM87462.1 - 0.0051 16.6 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 EIM87462.1 - 0.0059 16.5 1.2 0.016 15.1 0.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type RRM_1 PF00076.17 EIM87462.1 - 0.027 14.0 0.0 17 5.1 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WH1 PF00568.18 EIM87463.1 - 2.3e-11 43.4 0.2 1.4e-10 40.8 0.1 2.0 1 1 0 1 1 1 1 WH1 domain PBD PF00786.23 EIM87463.1 - 0.008 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pyr_redox_2 PF07992.9 EIM87464.1 - 1.1e-27 97.2 0.0 2.2e-27 96.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM87464.1 - 9.4e-13 48.3 0.0 1.7e-10 41.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM87464.1 - 0.0056 16.7 0.0 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Bac_rhodopsin PF01036.13 EIM87465.1 - 1.3e-35 122.6 17.4 1.7e-35 122.3 12.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF998 PF06197.8 EIM87465.1 - 4.9 6.4 25.2 0.59 9.4 10.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) SYF2 PF08231.7 EIM87466.1 - 5e-48 163.1 17.8 5e-48 163.1 12.3 1.4 2 0 0 2 2 2 1 SYF2 splicing factor RNase_E_G PF10150.4 EIM87466.1 - 0.01 15.0 1.0 0.01 15.0 0.7 2.0 1 1 1 2 2 2 0 Ribonuclease E/G family Lumazine_bd PF12870.2 EIM87466.1 - 0.13 12.3 0.3 0.13 12.3 0.2 2.2 2 1 0 2 2 2 0 Lumazine-binding domain 5_nucleotid PF05761.9 EIM87466.1 - 0.41 9.1 9.5 0.64 8.4 6.6 1.5 1 1 0 1 1 1 0 5' nucleotidase family 4HB_MCP_1 PF12729.2 EIM87466.1 - 6.6 6.0 9.6 0.12 11.6 0.5 2.4 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction MFS_1 PF07690.11 EIM87467.1 - 1.8e-31 109.1 37.4 2.6e-31 108.6 25.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Corona_S2 PF01601.11 EIM87467.1 - 0.19 9.8 0.0 0.27 9.2 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ORC3_N PF07034.6 EIM87468.1 - 7.9e-29 100.6 0.0 2.2e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus CHAD PF05235.9 EIM87468.1 - 0.013 15.0 1.4 0.25 10.8 0.9 2.5 1 1 1 2 2 2 0 CHAD domain DUF4611 PF15387.1 EIM87468.1 - 0.19 11.9 5.3 3.3 7.9 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Smg4_UPF3 PF03467.10 EIM87469.1 - 4e-35 121.3 0.4 4e-35 121.3 0.3 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family DUF4121 PF13497.1 EIM87469.1 - 0.032 13.2 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) F-box-like PF12937.2 EIM87470.1 - 5.7e-08 32.3 6.6 8.8e-07 28.5 4.6 2.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM87470.1 - 0.25 11.0 5.5 0.54 9.9 0.0 3.4 3 0 0 3 3 3 0 F-box domain CAP_N PF01213.14 EIM87471.1 - 0.15 11.3 0.3 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EIM87471.1 - 1.3 8.3 4.5 2.1 7.6 3.1 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.13 EIM87472.1 - 7.7e-44 149.5 0.0 1.2e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM87472.1 - 4.6e-07 29.6 13.0 7.6e-07 28.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ham1p_like PF01725.11 EIM87472.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Ham1 family Mre11_DNA_bind PF04152.9 EIM87473.1 - 5.5e-47 159.8 3.4 7.8e-47 159.3 0.0 2.6 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EIM87473.1 - 9.5e-26 90.4 0.4 1.7e-25 89.5 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM87473.1 - 2.6e-07 30.5 0.0 9.4e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RmuC PF02646.11 EIM87473.1 - 0.018 13.8 0.3 0.033 13.0 0.2 1.3 1 0 0 1 1 1 0 RmuC family CENP-B_dimeris PF09026.5 EIM87473.1 - 0.26 11.5 11.9 0.38 11.0 1.2 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mak16 PF04874.9 EIM87473.1 - 3.5 7.7 19.8 0.57 10.3 4.1 2.7 2 0 0 2 2 2 0 Mak16 protein C-terminal region TPT PF03151.11 EIM87474.1 - 2.3e-08 33.8 9.9 2.3e-08 33.8 6.8 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIM87474.1 - 0.55 10.2 30.8 1.8 8.6 9.4 2.5 2 1 0 2 2 2 0 EamA-like transporter family PAPS_reduct PF01507.14 EIM87476.1 - 8.7e-28 97.2 0.0 1.3e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Hamartin PF04388.7 EIM87476.1 - 1.7 7.2 10.0 2.2 6.8 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein Tetraspannin PF00335.15 EIM87477.1 - 0.11 11.6 7.2 0.14 11.3 3.9 2.0 2 1 0 2 2 2 0 Tetraspanin family MFS_1 PF07690.11 EIM87478.1 - 3e-39 134.7 20.8 3e-39 134.7 14.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM87478.1 - 0.027 14.2 2.9 0.029 14.1 0.0 2.6 3 0 0 3 3 3 0 MFS_1 like family Peptidase_M20 PF01546.23 EIM87479.1 - 7e-29 100.6 0.0 1.3e-28 99.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87479.1 - 2e-13 50.0 0.0 3.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIM87480.1 - 1.8e-32 112.4 0.0 3e-32 111.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM87480.1 - 1.5e-11 44.0 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ADC PF06314.6 EIM87481.1 - 9e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) adh_short PF00106.20 EIM87482.1 - 1.4e-21 77.0 0.0 2.2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87482.1 - 1.3e-10 41.5 0.0 1.7e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87482.1 - 2.9e-08 33.6 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM87482.1 - 0.013 15.2 0.2 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EIM87483.1 - 7e-12 45.5 1.1 1.5e-10 41.2 0.6 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM87483.1 - 0.032 13.8 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EIM87483.1 - 0.081 12.7 0.1 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SUZ PF12752.2 EIM87484.1 - 5.7e-13 49.1 4.8 1.8e-11 44.3 0.3 3.2 3 0 0 3 3 3 2 SUZ domain Ribosomal_S17 PF00366.15 EIM87485.1 - 1.6e-13 50.4 3.0 1.9e-13 50.2 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1469 PF07332.6 EIM87486.1 - 0.024 14.3 0.8 0.024 14.3 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Phage_antitermQ PF06530.7 EIM87486.1 - 0.24 10.9 1.2 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 Phage antitermination protein Q Epimerase PF01370.16 EIM87487.1 - 1.7e-50 171.6 0.0 2.3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIM87487.1 - 4.8e-08 32.2 0.0 2.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIM87487.1 - 3.2e-05 22.7 0.0 5.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIM87487.1 - 0.00025 20.0 0.1 0.013 14.3 0.1 2.7 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIM87487.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EIM87488.1 - 1.8e-66 223.9 0.0 2.4e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIM87488.1 - 4.5e-06 25.7 0.0 8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM87488.1 - 0.0026 16.6 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIM87488.1 - 0.0044 16.2 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM87488.1 - 0.011 15.8 0.0 0.029 14.3 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 EIM87488.1 - 0.042 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit TAA-Trp-ring PF15401.1 EIM87488.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DUF4446 PF14584.1 EIM87489.1 - 0.0082 15.9 2.6 3.9 7.3 0.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF4446) Laminin_I PF06008.9 EIM87489.1 - 0.24 10.6 12.6 1.1 8.5 1.8 2.5 1 1 1 2 2 2 0 Laminin Domain I Tropomyosin_1 PF12718.2 EIM87489.1 - 7.3 6.4 17.1 2.1 8.1 0.2 2.2 2 0 0 2 2 2 0 Tropomyosin like BPL_LplA_LipB PF03099.14 EIM87490.1 - 2.5e-19 69.4 0.0 4.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 EIM87490.1 - 1.7e-11 43.5 0.0 1.4e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal ABC_transp_aux PF09822.4 EIM87490.1 - 0.0033 16.9 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system BPL_C PF02237.12 EIM87490.1 - 0.02 14.6 0.4 0.28 10.9 0.3 2.5 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain Peptidase_S24 PF00717.18 EIM87491.1 - 6e-09 35.4 0.0 1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Aldo_ket_red PF00248.16 EIM87492.1 - 8.6e-40 136.3 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 EIM87493.1 - 1.3e-08 34.4 1.2 2.3e-07 30.4 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EIM87493.1 - 4.3 7.9 8.9 1.2 9.6 0.2 4.8 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EIM87493.1 - 6.7 6.4 8.2 2.7 7.7 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Peptidase_S24 PF00717.18 EIM87494.1 - 3.1e-07 29.9 0.0 5.3e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like DUF3096 PF11295.3 EIM87494.1 - 1 8.9 5.9 0.34 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) Ribosomal_S30 PF04758.9 EIM87495.1 - 3.7e-24 84.2 6.1 5.7e-24 83.6 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.17 EIM87496.1 - 6e-47 159.7 0.0 1.9e-46 158.0 0.0 1.8 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EIM87496.1 - 4.6e-33 113.6 0.0 2.1e-32 111.5 0.0 2.0 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EIM87496.1 - 1.3e-13 51.1 0.1 2.7e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Dihydroneopterin aldolase TPR_14 PF13428.1 EIM87497.1 - 1.7e-12 46.7 3.2 0.00082 19.7 0.0 5.1 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87497.1 - 1.7e-11 44.4 0.1 0.0007 20.1 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM87497.1 - 2e-11 43.3 0.0 3.2e-05 23.5 0.0 3.6 3 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 EIM87497.1 - 3.2e-10 39.1 0.0 0.17 11.8 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIM87497.1 - 3.7e-09 36.7 1.0 0.0017 18.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM87497.1 - 7.8e-08 31.5 0.0 0.28 11.0 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87497.1 - 8.3e-08 31.5 0.0 0.031 13.8 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM87497.1 - 3e-06 27.3 0.4 0.44 11.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM87497.1 - 2.5e-05 24.0 0.3 0.44 10.4 0.0 3.6 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM87497.1 - 8.6e-05 22.0 1.5 6.1 6.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIM87497.1 - 0.00016 21.7 0.7 0.17 12.0 0.4 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIM87497.1 - 0.00031 20.6 0.4 12 5.9 0.1 4.5 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIM87497.1 - 0.07 12.1 0.4 26 3.7 0.0 3.1 1 1 0 2 2 2 0 Tetratricopeptide repeat GPI-anchored PF10342.4 EIM87498.1 - 3.5e-07 30.6 0.9 3.5e-07 30.6 0.6 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EIM87499.1 - 5.1e-12 46.1 2.1 5.1e-12 46.1 1.4 2.4 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DXP_reductoisom PF02670.11 EIM87499.1 - 0.00046 20.7 1.5 0.00077 19.9 1.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sporozoite_P67 PF05642.6 EIM87499.1 - 0.31 8.8 10.5 0.46 8.2 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 EIM87499.1 - 2.5 6.2 8.5 2.8 6.1 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EIM87499.1 - 2.8 6.8 4.7 3.3 6.6 3.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RAP1 PF07218.6 EIM87499.1 - 3.8 5.4 12.5 4 5.4 8.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aldo_ket_red PF00248.16 EIM87501.1 - 9.8e-70 234.5 0.0 1.1e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EIM87502.1 - 4.9e-27 92.8 10.6 3.3e-09 36.2 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EIM87502.1 - 4.5e-08 33.0 0.2 0.00059 19.5 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A NifZ PF04319.8 EIM87502.1 - 0.0095 15.2 0.4 0.025 13.9 0.3 1.7 1 0 0 1 1 1 1 NifZ domain TFIIIC_delta PF12657.2 EIM87502.1 - 0.021 14.5 1.9 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DJ-1_PfpI PF01965.19 EIM87503.1 - 4.7e-24 84.5 0.2 7e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIM87503.1 - 3.3e-10 39.3 0.1 5.9e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family 4HBT PF03061.17 EIM87504.1 - 8.1e-08 32.2 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily GMC_oxred_N PF00732.14 EIM87505.1 - 1.3e-50 172.2 0.0 2.1e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87505.1 - 9.5e-29 100.5 0.0 1.9e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM87505.1 - 2.3e-09 36.6 0.0 3.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM87505.1 - 2e-06 26.9 1.5 2.4e-05 23.3 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EIM87505.1 - 5.6e-06 25.4 0.8 0.0018 17.1 0.1 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM87505.1 - 2e-05 24.5 0.7 6.6e-05 22.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM87505.1 - 7.8e-05 21.7 0.1 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM87505.1 - 0.0001 22.4 0.2 0.043 13.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM87505.1 - 0.0006 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM87505.1 - 0.002 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM87505.1 - 0.0027 16.2 0.0 0.0045 15.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIM87505.1 - 0.0029 16.7 1.6 0.0035 16.4 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM87505.1 - 0.0081 16.5 0.1 0.027 14.8 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM87505.1 - 0.028 14.1 0.1 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIM87505.1 - 0.034 13.2 0.0 0.093 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 EIM87505.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIM87505.1 - 0.096 11.2 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Fer2 PF00111.22 EIM87506.1 - 1.3e-10 40.9 0.1 1.8e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 EIM87506.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain DUF4131 PF13567.1 EIM87507.1 - 3.4 7.0 6.1 1.6 8.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-MYND PF01753.13 EIM87508.1 - 3e-07 30.2 15.9 5.8e-07 29.2 11.0 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIM87509.1 - 1.5e-07 31.1 17.0 2.9e-07 30.2 11.8 1.5 1 0 0 1 1 1 1 MYND finger Adap_comp_sub PF00928.16 EIM87510.1 - 2.2e-91 305.6 0.1 3.3e-91 305.0 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIM87510.1 - 6.3e-06 25.9 0.3 1.1e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EIM87510.1 - 0.0035 16.5 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain SH3_5 PF08460.5 EIM87510.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Spo7 PF03907.8 EIM87511.1 - 1.9e-10 40.7 3.7 1.9e-10 40.7 2.6 2.9 2 1 0 2 2 2 1 Spo7-like protein Ino80_Iec3 PF14612.1 EIM87512.1 - 0.06 13.4 0.2 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling p450 PF00067.17 EIM87513.1 - 8.5e-68 228.9 0.0 1.9e-67 227.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF4393 PF14337.1 EIM87513.1 - 0.046 13.1 0.2 1.1 8.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4393) DUF1688 PF07958.6 EIM87514.1 - 6.3e-164 545.4 0.0 7.1e-164 545.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PHP PF02811.14 EIM87516.1 - 2.8e-13 50.0 0.0 3.8e-13 49.6 0.0 1.3 1 1 0 1 1 1 1 PHP domain Glyco_hydro_28 PF00295.12 EIM87517.1 - 1.2e-24 86.9 7.6 4.9e-17 61.8 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 MFS_2 PF13347.1 EIM87519.1 - 1.6e-13 49.8 9.1 1.6e-13 49.8 6.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 EIM87519.1 - 6.7e-10 38.2 28.7 2.2e-08 33.2 19.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM87519.1 - 0.025 14.3 0.1 11 5.9 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family ETF_QO PF05187.8 EIM87520.1 - 4.3e-28 97.5 0.1 2.7e-20 72.3 0.0 2.3 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 EIM87520.1 - 1.5e-08 34.5 0.0 5.1e-08 32.8 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM87520.1 - 2.2e-07 30.1 0.0 3.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM87520.1 - 4.2e-06 25.8 0.6 0.00012 21.0 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM87520.1 - 4e-05 23.5 0.1 0.00011 22.1 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM87520.1 - 5.6e-05 22.3 0.0 0.00064 18.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EIM87520.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIM87520.1 - 0.00044 19.3 0.2 0.00044 19.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM87520.1 - 0.00046 18.7 0.6 0.0007 18.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM87520.1 - 0.0007 19.7 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM87520.1 - 0.0011 17.9 0.3 0.0017 17.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM87520.1 - 0.0064 15.6 0.2 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIM87520.1 - 0.02 13.5 0.4 0.033 12.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EIM87520.1 - 0.035 14.4 0.0 2.1 8.8 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM87520.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-MYND PF01753.13 EIM87521.1 - 1.4e-07 31.2 18.3 2.3e-07 30.5 12.7 1.3 1 0 0 1 1 1 1 MYND finger zf-C4_ClpX PF06689.8 EIM87521.1 - 0.026 14.0 2.9 0.06 12.8 2.0 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger ADH_zinc_N PF00107.21 EIM87523.1 - 3.4e-16 58.9 0.1 9.3e-16 57.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM87523.1 - 2.5e-10 40.1 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N PF08240.7 EIM87524.1 - 1.4e-25 89.2 5.3 2.3e-25 88.4 3.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM87524.1 - 4.5e-16 58.5 0.1 1.3e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIM87524.1 - 0.019 14.5 0.1 0.047 13.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EIM87524.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIM87524.1 - 0.042 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EIM87524.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Gp_dh_N PF00044.19 EIM87524.1 - 0.089 12.7 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.23 EIM87525.1 - 9.1e-38 129.7 0.0 5.9e-37 127.0 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM87525.1 - 7.6e-37 126.5 0.0 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIM87525.1 - 1.5e-11 44.2 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM87525.1 - 3.1e-09 36.9 0.0 6.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIM87525.1 - 0.0026 17.6 0.0 0.012 15.4 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM87525.1 - 0.0063 15.4 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIM87525.1 - 0.01 14.7 0.0 0.086 11.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EIM87525.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIM87525.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 KR domain DXP_reductoisom PF02670.11 EIM87525.1 - 0.091 13.2 0.1 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EIM87525.1 - 0.17 10.7 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EIM87525.1 - 0.21 10.2 0.0 0.47 9.1 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EIM87526.1 - 2.5e-33 115.2 30.1 2.6e-33 115.2 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EIM87526.1 - 0.018 15.4 2.3 2.5 8.5 0.1 2.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MoCF_biosynth PF00994.19 EIM87527.1 - 2.5e-32 111.2 0.0 4.1e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ribosomal_S18 PF01084.15 EIM87528.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 AAA_11 PF13086.1 EIM87529.1 - 3e-62 210.3 0.1 2.5e-61 207.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIM87529.1 - 8.7e-58 194.9 0.0 1.4e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIM87529.1 - 8.9e-11 41.7 0.1 0.016 14.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIM87529.1 - 2.1e-10 40.1 0.0 1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIM87529.1 - 1.2e-08 34.7 0.0 3.6e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM87529.1 - 2.5e-05 24.4 0.0 0.0014 18.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EIM87529.1 - 5e-05 22.7 0.0 0.0067 15.7 0.0 2.5 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EIM87529.1 - 5.2e-05 22.3 0.1 0.26 10.2 0.0 3.1 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EIM87529.1 - 5.6e-05 23.0 0.0 0.00041 20.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 EIM87529.1 - 0.00023 21.2 0.1 0.0092 16.0 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EIM87529.1 - 0.00029 20.8 0.1 0.00081 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 EIM87529.1 - 0.001 18.3 0.0 0.64 9.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.24 EIM87529.1 - 0.0086 16.2 0.1 0.05 13.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIM87529.1 - 0.011 15.1 0.0 0.035 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIM87529.1 - 0.014 15.6 0.0 0.071 13.4 0.0 2.0 1 1 0 2 2 2 0 AAA domain UvrD_C PF13361.1 EIM87529.1 - 0.062 12.7 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EIM87529.1 - 0.064 12.1 0.0 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.17 EIM87529.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase GATase_6 PF13522.1 EIM87530.1 - 6.1e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIM87530.1 - 1.7e-07 30.1 0.1 9.7e-07 27.7 0.0 2.1 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 EIM87530.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EIM87530.1 - 0.0016 17.1 0.2 0.0025 16.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II KH_5 PF13184.1 EIM87530.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NusA-like KH domain MCM PF00493.18 EIM87531.1 - 2.1e-133 444.2 0.0 2.8e-133 443.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIM87531.1 - 6.3e-20 71.8 0.1 9.4e-19 68.0 0.0 2.8 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EIM87531.1 - 1.4e-09 37.8 0.0 3.5e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIM87531.1 - 1.6e-07 30.7 0.0 7.4e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIM87531.1 - 0.00016 21.3 0.0 0.0023 17.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIM87531.1 - 0.00022 20.7 0.0 1.3 8.4 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EIM87531.1 - 0.071 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EIM87531.1 - 0.43 10.5 2.1 7 6.5 0.0 3.1 2 2 0 3 3 3 0 AAA ATPase domain RNA_pol_Rpc34 PF05158.7 EIM87532.1 - 9.8e-77 258.3 1.5 1.2e-64 218.5 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit MNE1 PF13762.1 EIM87532.1 - 0.048 13.7 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component DUF2207 PF09972.4 EIM87533.1 - 0.19 10.2 0.5 0.2 10.1 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex24p PF06398.6 EIM87533.1 - 0.82 8.4 6.4 7.2 5.3 4.4 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin CBM_1 PF00734.13 EIM87534.1 - 1.4e-11 43.8 16.3 1.4e-11 43.8 11.3 2.7 4 0 0 4 4 4 1 Fungal cellulose binding domain Chorion_3 PF05387.6 EIM87534.1 - 0.052 12.9 3.3 0.071 12.5 2.3 1.2 1 0 0 1 1 1 0 Chorion family 3 C2 PF00168.25 EIM87535.1 - 3.3e-25 87.7 0.0 7.7e-16 57.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain HLH PF00010.21 EIM87538.1 - 1.5e-12 46.9 0.1 4.2e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.1 EIM87538.1 - 0.34 11.3 9.0 0.28 11.6 3.9 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Mtp PF03821.11 EIM87539.1 - 0.051 12.9 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter PH_10 PF15411.1 EIM87539.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain HAUS4 PF14735.1 EIM87540.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Tannase PF07519.6 EIM87541.1 - 2.9e-91 306.5 0.0 6.3e-91 305.4 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Arch_ATPase PF01637.13 EIM87542.1 - 3.1e-12 46.6 0.0 7.8e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EIM87542.1 - 3e-06 27.3 0.1 1.2e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RNA12 PF10443.4 EIM87542.1 - 0.0008 18.0 0.0 0.0048 15.4 0.0 2.0 2 0 0 2 2 2 1 RNA12 protein AAA_14 PF13173.1 EIM87542.1 - 0.0013 18.5 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM87542.1 - 0.0029 17.7 0.0 0.5 10.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EIM87542.1 - 0.009 16.2 0.0 6.7 6.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2587 PF10759.4 EIM87542.1 - 0.13 11.5 0.9 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) DUF258 PF03193.11 EIM87542.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ribonucleas_3_3 PF14622.1 EIM87543.1 - 1.7e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM87543.1 - 1.9e-07 31.5 0.0 5.2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Piwi PF02171.12 EIM87544.1 - 6.9e-85 284.6 0.0 8.9e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIM87544.1 - 4e-21 74.7 0.0 7.6e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIM87544.1 - 5.8e-19 67.2 0.1 1.4e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ApbA_C PF08546.6 EIM87545.1 - 1.3e-20 73.6 0.0 5.7e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIM87545.1 - 8e-16 57.8 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Peptidase_M10 PF00413.19 EIM87545.1 - 0.13 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Matrixin DHH PF01368.15 EIM87547.1 - 1.3e-13 50.8 0.0 2.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 EIM87547.1 - 3.7e-09 36.8 0.0 0.0021 18.2 0.0 2.3 2 0 0 2 2 2 2 DHHA2 domain Urm1 PF09138.6 EIM87548.1 - 6.8e-35 119.0 0.0 1.4e-33 114.8 0.0 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EIM87548.1 - 1.4e-05 25.3 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family Complex1_LYR_1 PF13232.1 EIM87549.1 - 1.3e-15 57.3 1.3 1.6e-15 57.0 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIM87549.1 - 9.2e-14 50.9 0.3 1.2e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MFS_1 PF07690.11 EIM87550.1 - 3.1e-39 134.6 28.5 3.1e-39 134.6 19.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87550.1 - 5.4e-14 51.6 2.9 5.4e-14 51.6 2.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter NKAIN PF05640.9 EIM87550.1 - 0.042 12.8 0.2 0.084 11.8 0.1 1.5 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein FtsX PF02687.16 EIM87550.1 - 10 5.9 32.1 1.9 8.2 1.3 4.6 3 1 1 4 4 4 0 FtsX-like permease family PQ-loop PF04193.9 EIM87551.1 - 9.9e-19 66.6 19.2 7.2e-10 38.2 0.6 3.9 4 0 0 4 4 4 2 PQ loop repeat Polysacc_synt PF01943.12 EIM87551.1 - 0.00035 19.9 3.8 0.00035 19.9 2.6 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Phage_GP20 PF06810.6 EIM87552.1 - 0.15 11.4 10.8 0.015 14.7 3.0 2.6 3 0 0 3 3 3 0 Phage minor structural protein GP20 Pox_A_type_inc PF04508.7 EIM87552.1 - 5.9 6.9 9.8 28 4.8 0.0 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 EIM87552.1 - 6.8 5.7 19.5 0.099 11.8 3.5 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein TPR_14 PF13428.1 EIM87553.1 - 1.5e-25 87.3 29.8 8.2e-06 26.0 0.1 12.3 5 2 10 15 15 13 6 Tetratricopeptide repeat HAT PF02184.11 EIM87553.1 - 1.4e-21 75.8 64.4 4.5e-07 29.5 3.4 14.6 15 1 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EIM87553.1 - 1.7e-21 76.3 4.0 0.0001 22.5 0.1 7.5 6 2 4 10 10 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87553.1 - 1.2e-18 67.2 23.4 3.2e-05 24.4 0.3 8.6 5 2 3 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EIM87553.1 - 2.2e-17 61.5 11.5 0.048 13.5 0.2 9.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIM87553.1 - 1.1e-13 50.6 8.1 0.0019 17.7 0.1 5.8 5 0 0 5 5 5 3 TPR repeat TPR_7 PF13176.1 EIM87553.1 - 2.9e-10 39.1 15.6 0.26 11.1 0.0 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87553.1 - 2e-09 37.2 11.2 0.39 10.6 0.0 7.7 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87553.1 - 1.2e-08 34.1 0.1 0.19 11.3 0.2 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM87553.1 - 1.8e-08 33.5 4.1 1.2 9.0 0.1 7.3 7 1 1 8 8 7 1 Tetratricopeptide repeat SNAP PF14938.1 EIM87553.1 - 5.1e-08 32.4 7.6 0.00037 19.7 0.5 4.2 4 0 0 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_17 PF13431.1 EIM87553.1 - 6.9e-07 28.9 4.1 0.011 15.8 0.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIM87553.1 - 1.4e-06 27.6 25.2 0.27 10.2 2.5 5.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIM87553.1 - 9.7e-06 25.3 9.3 1.8 8.5 0.2 5.6 3 1 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM87553.1 - 0.0013 18.5 4.0 4.7 7.1 0.0 5.3 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EIM87553.1 - 0.0018 18.5 20.9 19 6.0 0.0 9.0 10 1 0 10 10 9 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EIM87553.1 - 0.016 14.9 0.5 0.016 14.9 0.4 6.4 4 3 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 c-SKI_SMAD_bind PF08782.5 EIM87553.1 - 1.6 8.9 5.0 49 4.1 0.1 4.6 5 0 0 5 5 5 0 c-SKI Smad4 binding domain DUF3836 PF12930.2 EIM87553.1 - 2.7 7.5 7.2 8.3 5.9 1.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF3836) TGT PF01702.13 EIM87554.1 - 1.7e-24 86.4 0.0 3.1e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase AMP-binding PF00501.23 EIM87555.1 - 6.8e-36 123.5 0.0 1.5e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIM87555.1 - 3.7e-31 107.9 0.0 9e-31 106.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIM87555.1 - 1.6e-08 34.3 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM87555.1 - 3.1e-05 24.1 0.0 6.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIM87555.1 - 0.0023 16.6 0.0 0.0054 15.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ PF00226.26 EIM87556.1 - 2.8e-21 75.0 0.5 4.9e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Rod_C PF10493.4 EIM87556.1 - 0.13 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Aldo_ket_red PF00248.16 EIM87557.1 - 3.9e-70 235.8 0.1 4.4e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM87558.1 - 4.9e-73 245.3 0.0 5.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM87559.1 - 1.8e-56 191.0 0.0 8.7e-28 96.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PAF-AH_p_II PF03403.8 EIM87560.1 - 1.9e-47 161.4 0.0 7.9e-32 109.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EIM87560.1 - 8.9e-15 54.7 0.1 6e-14 52.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIM87560.1 - 6.8e-11 41.5 0.0 8.6e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIM87560.1 - 3.1e-10 40.3 0.3 2.4e-09 37.3 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EIM87560.1 - 5e-09 35.3 0.0 2.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Thioesterase PF00975.15 EIM87560.1 - 0.0097 16.1 0.0 0.071 13.3 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 EIM87560.1 - 0.031 13.8 0.0 0.074 12.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 EIM87560.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EIM87560.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase UPF0227 PF05728.7 EIM87560.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Aldo_ket_red PF00248.16 EIM87561.1 - 6.4e-73 245.0 0.0 7.1e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_18 PF15024.1 EIM87562.1 - 3e-10 39.0 0.0 4.7e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_trans_1_4 PF13692.1 EIM87562.1 - 0.0045 17.1 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Aldo_ket_red PF00248.16 EIM87563.1 - 6.6e-71 238.4 0.0 8.1e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GNAT_acetyltran PF12746.2 EIM87563.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Ribosomal_S8 PF00410.14 EIM87564.1 - 4.3e-26 91.2 0.1 6.1e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 EIM87565.1 - 3.1e-56 188.3 0.2 3.9e-56 188.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EIM87565.1 - 0.038 14.6 0.1 0.12 13.0 0.0 1.8 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal Lactonase PF10282.4 EIM87566.1 - 1e-10 41.2 0.0 6.4e-08 32.0 0.0 2.9 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller CTP_transf_1 PF01148.15 EIM87568.1 - 1e-15 58.1 3.6 1e-11 44.9 0.5 2.3 1 1 1 2 2 2 2 Cytidylyltransferase family DNA_pol_A_exo1 PF01612.15 EIM87569.1 - 6.3e-20 71.3 0.1 1.3e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Whi5 PF08528.6 EIM87569.1 - 1.7e-06 27.4 0.4 5.8e-06 25.7 0.3 2.0 1 0 0 1 1 1 1 Whi5 like DnaJ PF00226.26 EIM87570.1 - 2e-19 69.0 0.4 7.6e-19 67.2 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain Adeno_100 PF02438.11 EIM87570.1 - 0.27 9.3 1.6 0.47 8.6 1.1 1.3 1 0 0 1 1 1 0 Late 100kD protein SpoVR PF04293.8 EIM87570.1 - 9.1 4.5 10.0 15 3.8 7.0 1.3 1 0 0 1 1 1 0 SpoVR like protein UQ_con PF00179.21 EIM87571.1 - 2.1e-49 166.5 0.0 2.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM87571.1 - 4.7e-07 29.6 0.0 7e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B Alpha_L_fucos PF01120.12 EIM87573.1 - 5.3e-71 239.3 7.1 8.3e-52 176.1 4.7 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase Copper-fist PF00649.13 EIM87575.1 - 7.5e-23 79.4 8.1 1.1e-22 78.9 0.8 2.2 1 1 1 2 2 2 2 Copper fist DNA binding domain zinc-ribbons_6 PF07191.7 EIM87575.1 - 0.056 13.2 4.1 0.075 12.8 2.8 1.2 1 0 0 1 1 1 0 zinc-ribbons Metallothio_Pro PF02069.11 EIM87575.1 - 0.073 12.9 0.5 0.073 12.9 0.4 2.6 2 1 0 2 2 2 0 Prokaryotic metallothionein WD40 PF00400.27 EIM87580.1 - 5.4e-34 114.8 5.5 1e-07 31.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIM87580.1 - 0.011 14.0 0.1 0.38 8.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nha1_C PF08619.5 EIM87580.1 - 0.068 12.4 9.5 0.13 11.4 6.6 1.4 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Aminotran_1_2 PF00155.16 EIM87581.1 - 2.4e-41 141.8 0.0 3.3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myotoxins PF00819.12 EIM87581.1 - 0.068 13.2 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Myotoxin Beta_elim_lyase PF01212.16 EIM87581.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIM87581.1 - 0.21 9.8 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PDH PF02153.12 EIM87582.1 - 9.7e-15 54.1 0.0 1.3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EIM87582.1 - 2.2e-05 24.3 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIM87582.1 - 0.00013 22.3 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EIM87582.1 - 0.00016 21.1 0.0 0.00069 19.0 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EIM87582.1 - 0.0023 18.0 0.0 0.0052 16.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EIM87582.1 - 0.0053 15.9 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIM87582.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EIM87582.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 ThiF family 2OG-FeII_Oxy PF03171.15 EIM87583.1 - 2.1e-11 43.9 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM87583.1 - 8.9e-09 35.9 0.0 1.9e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Dus PF01207.12 EIM87584.1 - 5.6e-49 166.6 0.0 8.2e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EIM87584.1 - 4.5e-08 32.5 6.7 0.002 17.7 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FA_desaturase PF00487.19 EIM87585.1 - 1.8e-26 93.1 23.1 2.8e-26 92.5 16.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIM87585.1 - 3.4e-05 23.8 0.1 6.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.8 EIM87586.1 - 4.7e-38 130.8 0.0 6.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM87586.1 - 0.0004 20.3 0.5 0.00079 19.3 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM87586.1 - 0.00093 18.4 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EIM87586.1 - 0.004 15.9 0.0 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EIM87586.1 - 0.01 14.7 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EIM87586.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM87586.1 - 0.099 12.8 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 EIM87587.1 - 1.7e-14 53.9 0.0 3.5e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM87587.1 - 1.1e-07 31.9 0.3 1.8e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM87587.1 - 0.004 16.9 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EIM87587.1 - 0.026 13.0 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF775 PF05603.7 EIM87588.1 - 1.6e-47 161.6 0.0 1.8e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Abhydrolase_6 PF12697.2 EIM87589.1 - 2.8e-08 33.9 0.0 4.7e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM87589.1 - 0.0019 17.9 0.0 0.01 15.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tox-SHH PF15652.1 EIM87589.1 - 0.038 14.5 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature DUSP PF06337.7 EIM87589.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 DUSP domain HMGL-like PF00682.14 EIM87590.1 - 7e-48 163.3 0.0 1.1e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LVIVD PF08309.6 EIM87591.1 - 0.00023 20.1 0.2 0.00058 18.7 0.1 1.6 1 0 0 1 1 1 1 LVIVD repeat DUF3557 PF12078.3 EIM87591.1 - 0.13 11.9 0.3 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) LRR_1 PF00560.28 EIM87591.1 - 4 7.8 5.0 1.1e+02 3.4 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Glyco_hydro_cc PF11790.3 EIM87592.1 - 1.1e-71 241.0 5.8 1.3e-71 240.8 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core F-box-like PF12937.2 EIM87593.1 - 0.0022 17.6 0.2 0.0022 17.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EIM87593.1 - 0.0054 16.6 2.2 0.5 10.5 0.1 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 EIM87593.1 - 0.013 15.4 4.8 12 6.4 0.1 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat UCR_Fe-S_N PF10399.4 EIM87593.1 - 0.25 10.5 1.8 2.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LRR_4 PF12799.2 EIM87593.1 - 0.44 10.2 8.0 0.62 9.7 0.7 3.4 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM87593.1 - 0.67 9.7 6.6 1.3 8.8 0.7 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 EIM87593.1 - 1.5 9.3 6.4 35 5.2 0.1 5.0 4 0 0 4 4 4 0 Leucine rich repeat DSBA PF01323.15 EIM87594.1 - 8.4e-20 71.1 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EIM87594.1 - 0.0029 17.6 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SNF2_N PF00176.18 EIM87595.1 - 1.3e-73 247.3 0.1 2.5e-73 246.5 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM87595.1 - 1.6e-15 56.6 0.0 3.5e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM87595.1 - 7.4e-05 22.6 0.0 0.00024 21.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EIM87595.1 - 0.15 10.8 4.4 0.44 9.3 0.1 2.8 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 EST1_DNA_bind PF10373.4 EIM87596.1 - 9.3e-29 100.4 0.0 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EIM87596.1 - 8.5e-13 48.4 0.0 2.4e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 Telomerase activating protein Est1 TPR_16 PF13432.1 EIM87596.1 - 0.041 14.5 1.9 0.077 13.6 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87596.1 - 0.046 13.6 0.9 0.18 11.7 0.6 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM87596.1 - 0.09 12.4 0.4 0.25 10.9 0.3 1.7 1 0 0 1 1 1 0 TPR repeat PPP4R2 PF09184.6 EIM87596.1 - 0.13 11.8 1.9 0.2 11.2 1.3 1.2 1 0 0 1 1 1 0 PPP4R2 ArfGap PF01412.13 EIM87598.1 - 3.6e-36 123.4 0.3 6.1e-36 122.7 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Nbs1_C PF08599.5 EIM87598.1 - 0.075 12.9 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 DUF2167 PF09935.4 EIM87599.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Aminotran_1_2 PF00155.16 EIM87600.1 - 1.6e-48 165.5 0.0 4.4e-46 157.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 EIM87600.1 - 0.00026 19.6 0.0 0.00071 18.2 0.0 1.6 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EIM87600.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIM87600.1 - 0.0077 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Tmemb_18A PF09771.4 EIM87600.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Zn_Tnp_IS91 PF14319.1 EIM87601.1 - 1.8 8.1 7.8 1.1 8.8 1.2 2.0 1 1 0 1 1 1 0 Transposase zinc-binding domain adh_short PF00106.20 EIM87602.1 - 4.2e-21 75.5 0.0 6.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM87602.1 - 2.5e-08 33.7 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM87602.1 - 4.8e-08 33.0 0.0 6.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIM87602.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_1_2 PF00155.16 EIM87603.1 - 6.5e-52 176.6 0.0 3.9e-44 151.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIM87603.1 - 9.6e-05 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIM87603.1 - 0.00035 19.2 0.0 0.00061 18.4 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EIM87603.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V UDPG_MGDP_dh_N PF03721.9 EIM87604.1 - 3e-57 192.9 0.0 6e-57 192.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EIM87604.1 - 1.8e-33 114.8 0.3 7.6e-33 112.8 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EIM87604.1 - 8e-31 106.1 0.0 1.7e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.1 EIM87604.1 - 0.057 13.6 1.5 6.4 7.0 0.1 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EIM87604.1 - 0.096 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase DSPc PF00782.15 EIM87605.1 - 2e-31 108.3 0.0 2.7e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EIM87605.1 - 0.00013 21.0 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EIM87605.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Adenylsucc_synt PF00709.16 EIM87605.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Ras PF00071.17 EIM87606.1 - 5.1e-55 185.2 0.0 5.9e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM87606.1 - 1.3e-15 57.9 0.0 1.8e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM87606.1 - 1.4e-06 27.6 0.0 2.3e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM87606.1 - 0.0025 17.0 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIM87606.1 - 0.053 12.6 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIM87606.1 - 0.11 12.0 0.0 11 5.4 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pro_CA PF00484.14 EIM87607.1 - 8e-43 146.0 0.1 9.6e-43 145.8 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase mono-CXXC PF15626.1 EIM87607.1 - 1.3 8.9 3.5 6.7 6.7 1.5 2.3 2 0 0 2 2 2 0 single CXXC unit Proteasome PF00227.21 EIM87611.1 - 2.9e-37 127.8 0.0 3.4e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SLD3 PF08639.5 EIM87613.1 - 2.1e-06 26.6 38.7 3.6e-05 22.5 26.9 2.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 Peptidase_M16 PF00675.15 EIM87614.1 - 5.4e-25 87.8 0.1 1.1e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIM87614.1 - 0.049 13.3 0.0 0.25 11.0 0.0 2.0 1 1 0 1 1 1 0 Peptidase M16 inactive domain zf-C2H2 PF00096.21 EIM87616.1 - 9.2e-09 35.1 6.9 0.0006 20.0 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM87616.1 - 5.1e-07 29.6 3.7 0.00091 19.4 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM87616.1 - 2.5e-05 24.2 9.8 0.002 18.3 0.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EIM87616.1 - 0.02 15.0 2.3 0.035 14.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EIM87616.1 - 0.29 10.8 5.0 4.3 7.1 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sec10 PF07393.6 EIM87617.1 - 1.9e-106 356.9 0.0 4.7e-77 259.7 0.0 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box PF00646.28 EIM87617.1 - 2.3e-05 23.9 0.2 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM87617.1 - 0.00017 21.2 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like IDO PF01231.13 EIM87618.1 - 1.8e-90 303.4 0.0 2.2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase BPL_C PF02237.12 EIM87619.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Cu-oxidase PF00394.17 EIM87621.1 - 3.5e-50 170.0 0.0 5.6e-46 156.3 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM87621.1 - 2.4e-39 134.0 1.9 2.4e-35 121.0 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM87621.1 - 4.4e-39 132.8 0.1 2.7e-37 127.0 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Sigma70_ECF PF07638.6 EIM87622.1 - 0.0096 15.6 0.6 0.022 14.4 0.3 1.6 2 0 0 2 2 2 1 ECF sigma factor PulG PF11773.3 EIM87622.1 - 0.15 11.7 0.2 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin TMEM154 PF15102.1 EIM87622.1 - 0.5 10.0 10.1 18 5.0 7.0 2.7 1 1 0 1 1 1 0 TMEM154 protein family AdoMet_MTase PF07757.8 EIM87623.1 - 9e-34 115.9 0.0 5.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EIM87623.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PGI PF00342.14 EIM87624.1 - 1.9e-210 699.3 0.1 2.2e-210 699.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Fungal_trans PF04082.13 EIM87625.1 - 3.5e-23 81.8 0.0 5.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM87625.1 - 2.2e-05 24.2 12.9 3.3e-05 23.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_red PF03358.10 EIM87626.1 - 6.8e-09 35.3 0.0 9.9e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EIM87626.1 - 1.2e-08 35.0 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EIM87626.1 - 4.8e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold AA_permease_2 PF13520.1 EIM87629.1 - 6e-84 282.0 41.1 7.7e-84 281.6 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM87629.1 - 2.8e-18 65.5 35.4 4.3e-18 64.9 24.6 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM87630.1 - 4e-57 193.6 58.8 4.9e-57 193.3 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM87630.1 - 2.4e-14 52.5 49.6 6.8e-14 51.0 34.4 1.6 1 1 0 1 1 1 1 Amino acid permease DUF1469 PF07332.6 EIM87630.1 - 0.066 12.9 0.2 0.066 12.9 0.1 5.1 4 2 0 4 4 4 0 Protein of unknown function (DUF1469) ALMT PF11744.3 EIM87630.1 - 6.1 5.3 9.1 3.9 6.0 0.1 2.7 3 0 0 3 3 3 0 Aluminium activated malate transporter DIOX_N PF14226.1 EIM87631.1 - 4.3e-14 53.0 0.0 7.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM87631.1 - 3.3e-12 46.5 0.0 5.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM87632.1 - 7.3e-15 55.5 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM87632.1 - 7.6e-12 45.3 0.0 2.1e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 EIM87633.1 - 0.57 9.1 11.5 0.86 8.6 7.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EIM87633.1 - 4.2 5.2 8.8 5.5 4.9 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_3 PF01494.14 EIM87634.1 - 6e-67 226.1 0.0 7.5e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM87634.1 - 8.8e-09 34.7 0.8 9.3e-06 24.7 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIM87634.1 - 4.7e-07 29.1 0.1 1.2e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIM87634.1 - 1.2e-06 28.7 0.7 0.0011 19.3 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM87634.1 - 5.9e-06 24.9 1.4 5.6e-05 21.7 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EIM87634.1 - 6.7e-06 26.0 0.1 2.4e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM87634.1 - 6.7e-05 21.6 0.4 0.00011 20.9 0.3 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIM87634.1 - 0.0003 20.9 0.0 0.00073 19.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM87634.1 - 0.0005 19.2 0.1 0.00081 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM87634.1 - 0.00068 19.5 1.3 0.0077 16.1 0.7 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM87634.1 - 0.0015 17.4 0.1 0.0025 16.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EIM87634.1 - 0.007 16.6 0.1 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIM87634.1 - 0.015 15.0 0.5 0.034 13.9 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM87634.1 - 0.044 12.7 0.6 0.068 12.0 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EIM87634.1 - 0.058 12.2 0.1 0.093 11.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldose_epim PF01263.15 EIM87635.1 - 8e-53 179.4 0.1 4.4e-41 140.9 0.0 2.0 2 0 0 2 2 2 2 Aldose 1-epimerase DUF4098 PF13345.1 EIM87636.1 - 0.00059 19.7 1.0 7.3 6.6 0.0 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF4098) T2SE_Nter PF05157.10 EIM87636.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain HMA PF00403.21 EIM87636.1 - 0.18 11.9 0.2 0.48 10.6 0.0 1.7 2 0 0 2 2 2 0 Heavy-metal-associated domain RRM_1 PF00076.17 EIM87638.1 - 6.7e-20 70.4 0.0 2.8e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM87638.1 - 1.3e-17 63.4 0.0 1.3e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM87638.1 - 2.3e-05 24.1 0.0 0.0053 16.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1275 PF06912.6 EIM87639.1 - 2.7e-20 72.4 15.5 4e-20 71.9 10.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Peptidase_M24 PF00557.19 EIM87640.1 - 2.4e-13 50.1 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 JAB PF01398.16 EIM87641.1 - 3.5e-29 100.8 0.1 7e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIM87641.1 - 8.9e-07 28.4 0.0 2e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Ribosomal_L18ae PF01775.12 EIM87642.1 - 3e-59 198.3 0.8 3.7e-59 198.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF1891 PF09004.5 EIM87642.1 - 0.15 11.4 0.8 0.35 10.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) EAP30 PF04157.11 EIM87643.1 - 3.1e-43 147.5 0.0 3.6e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family GPI-anchored PF10342.4 EIM87644.1 - 3.1e-08 33.9 1.9 3.1e-08 33.9 1.3 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3682 PF12446.3 EIM87644.1 - 2.5 8.3 17.0 4.6 7.5 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Tweety PF04906.8 EIM87645.1 - 0.064 11.6 1.4 0.11 10.9 1.0 1.3 1 0 0 1 1 1 0 Tweety Amidase PF01425.16 EIM87646.1 - 6e-79 265.9 0.0 8.3e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Amidase RPA_interact_N PF14766.1 EIM87647.1 - 0.013 14.9 1.7 0.062 12.7 1.2 2.0 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Latarcin PF10279.4 EIM87647.1 - 0.26 11.4 2.1 0.27 11.4 0.5 1.7 2 0 0 2 2 2 0 Latarcin precursor Vpu PF00558.14 EIM87648.1 - 2.3 7.8 2.9 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Vpu protein HTH_23 PF13384.1 EIM87651.1 - 0.1 12.2 0.2 10 5.9 0.0 2.8 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIM87651.1 - 0.33 10.1 7.0 6.8 5.9 0.1 4.1 4 1 1 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 Strep_pep PF14404.1 EIM87651.1 - 1.8 8.8 7.3 7.4 6.8 0.2 3.4 1 1 2 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species Nol1_Nop2_Fmu PF01189.12 EIM87652.1 - 2.3e-33 115.8 0.0 1.5e-28 99.9 0.0 3.0 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EIM87652.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF4559 PF15112.1 EIM87653.1 - 2.8 7.0 5.4 0.24 10.5 0.8 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) RdRP PF05183.7 EIM87654.1 - 6.6e-149 497.2 0.0 9.1e-149 496.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 EIM87655.1 - 2e-148 495.6 0.0 7e-148 493.8 0.0 1.8 2 0 0 2 2 2 1 RNA dependent RNA polymerase eIF3g PF12353.3 EIM87656.1 - 1.6e-40 137.9 2.1 3.2e-40 137.0 1.4 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EIM87656.1 - 2.1e-18 65.6 0.0 3.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM87656.1 - 9.5e-16 57.5 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM87656.1 - 1.3e-09 37.7 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM87656.1 - 0.021 14.6 0.2 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif F-box-like PF12937.2 EIM87657.1 - 1.1e-08 34.6 0.7 1.1e-08 34.6 0.5 1.8 2 0 0 2 2 2 1 F-box-like Ammonium_transp PF00909.16 EIM87658.1 - 8.9e-117 389.9 28.8 1e-116 389.7 20.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Cys_Met_Meta_PP PF01053.15 EIM87659.1 - 6.3e-126 419.7 0.0 2.3e-98 329.0 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIM87659.1 - 3e-05 23.1 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIM87659.1 - 0.00029 20.0 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EIM87659.1 - 0.0019 16.5 0.0 0.0027 16.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Las1 PF04031.8 EIM87659.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Las1-like LRR19-TM PF15176.1 EIM87660.1 - 0.051 13.2 0.1 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF3445 PF11927.3 EIM87662.1 - 2.2e-58 197.6 0.0 1.6e-43 148.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) DUF3445 PF11927.3 EIM87663.1 - 4.4e-54 183.4 0.0 6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ring_hydroxyl_A PF00848.14 EIM87664.1 - 3.1e-36 124.9 5.2 4.6e-36 124.4 2.2 2.2 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EIM87664.1 - 4.8e-14 51.6 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.11 EIM87665.1 - 2.2e-45 154.9 43.6 2.2e-45 154.9 30.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87665.1 - 7.7e-17 61.0 40.9 1.5e-16 60.0 8.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EIM87665.1 - 3.7e-08 32.0 21.9 7.4e-08 31.0 15.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP-synt_8 PF00895.15 EIM87665.1 - 2.8 8.2 5.8 27 5.0 0.0 4.3 4 0 0 4 4 4 0 ATP synthase protein 8 HpcH_HpaI PF03328.9 EIM87667.1 - 2.6e-33 114.7 0.0 3.6e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF4514 PF14986.1 EIM87667.1 - 0.043 13.6 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) PK PF00224.16 EIM87667.1 - 0.082 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Ferritin_2 PF13668.1 EIM87668.1 - 9.2e-48 161.6 2.4 1.5e-47 161.0 1.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain zf-C2H2_4 PF13894.1 EIM87672.1 - 0.12 12.7 3.6 0.12 12.7 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Gastrin PF00918.12 EIM87673.1 - 0.16 12.8 2.0 0.43 11.4 1.4 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family CBM_20 PF00686.14 EIM87674.1 - 7.2e-34 115.2 0.3 1.8e-33 113.9 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 EIM87674.1 - 1.3e-20 74.0 0.0 3.3e-20 72.7 0.0 1.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIM87674.1 - 9.6e-09 35.2 0.0 2.9e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Citrate_synt PF00285.16 EIM87675.1 - 4.2e-18 65.1 0.0 5.1e-16 58.3 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EIM87675.1 - 5.6e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EIM87675.1 - 1.8e-13 50.8 0.0 4.6e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EIM87675.1 - 7.8e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EIM87675.1 - 3.3e-05 23.5 0.0 0.00012 21.7 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Rad60-SLD_2 PF13881.1 EIM87678.1 - 1e-13 51.1 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIM87678.1 - 0.071 12.5 0.3 0.41 10.0 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin family COesterase PF00135.23 EIM87679.1 - 1.8e-96 324.0 0.0 2.1e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM87679.1 - 1.8e-09 37.4 0.2 4.7e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.21 EIM87680.1 - 1.3e-10 41.2 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Glyco_hydro_20 PF00728.17 EIM87681.1 - 6e-39 134.1 0.1 1.3e-38 133.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EIM87681.1 - 0.0023 18.4 0.0 0.0057 17.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DEP PF00610.16 EIM87682.1 - 0.023 14.4 0.1 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) R3H PF01424.17 EIM87683.1 - 8.3e-09 35.0 0.1 1.3e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EIM87683.1 - 0.00038 20.3 39.0 0.00048 20.0 7.3 13.4 14 1 0 14 14 14 7 NF-X1 type zinc finger Transp_cyt_pur PF02133.10 EIM87684.1 - 1.9e-35 122.2 35.2 6.9e-35 120.4 24.4 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TBCA PF02970.11 EIM87685.1 - 0.062 13.3 0.3 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A E2R135 PF11570.3 EIM87685.1 - 0.1 12.6 0.5 0.18 11.9 0.4 1.2 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Filament PF00038.16 EIM87685.1 - 0.16 11.3 0.9 0.22 10.9 0.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein TFIIA_gamma_N PF02268.11 EIM87686.1 - 3.6e-26 90.4 0.2 5.5e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EIM87686.1 - 1.2e-24 85.8 0.7 1.7e-24 85.3 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit APH PF01636.18 EIM87687.1 - 3e-12 46.7 0.9 3.5e-10 40.0 0.0 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family F-box PF00646.28 EIM87688.1 - 2.6e-07 30.1 0.1 1.1e-06 28.1 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM87688.1 - 3.3e-07 29.9 0.0 7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIM87688.1 - 9.3 6.0 9.2 33 4.3 0.1 5.3 7 0 0 7 7 7 0 Leucine rich repeat RVP_2 PF08284.6 EIM87689.1 - 0.063 13.2 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Phosphoprotein PF00922.12 EIM87689.1 - 1.2 8.2 4.7 3.2 6.8 3.3 1.7 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-MYND PF01753.13 EIM87691.1 - 1.6e-11 43.8 9.8 1.6e-11 43.8 6.8 2.9 2 1 0 2 2 2 1 MYND finger SET PF00856.23 EIM87691.1 - 2.8e-11 43.9 0.0 2.9e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 SET domain CH PF00307.26 EIM87692.1 - 3.4e-67 223.2 0.0 2.3e-18 66.1 0.0 4.7 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EIM87692.1 - 5e-06 26.0 0.0 1.2 8.8 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EIM87692.1 - 0.00022 20.3 0.0 0.53 9.7 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EIM87692.1 - 0.00024 21.1 0.8 0.00083 19.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EIM87692.1 - 0.0012 18.5 0.1 0.039 13.8 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 EIM87692.1 - 0.019 14.3 0.8 0.15 11.4 0.2 2.7 2 0 0 2 2 2 0 EF hand Herpes_UL25 PF01499.11 EIM87693.1 - 0.053 11.8 0.3 0.087 11.1 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Integrase_AP2 PF14657.1 EIM87693.1 - 0.13 12.0 1.6 0.37 10.5 1.1 1.8 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain DUF724 PF05266.9 EIM87693.1 - 0.17 11.4 5.5 0.26 10.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PEARLI-4 PF05278.7 EIM87693.1 - 0.2 10.9 7.1 0.31 10.3 4.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF572 PF04502.8 EIM87693.1 - 0.68 9.0 6.7 0.17 11.1 2.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) MAGE_N PF12440.3 EIM87693.1 - 1.1 9.5 11.2 0.056 13.7 1.4 2.6 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal DAO PF01266.19 EIM87695.1 - 1.2e-52 179.0 0.1 1.4e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM87695.1 - 1.6e-05 25.0 0.0 0.026 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM87695.1 - 0.00018 21.4 0.1 0.00042 20.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM87695.1 - 0.00046 19.9 0.1 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EIM87695.1 - 0.0015 17.1 0.1 0.065 11.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EIM87695.1 - 0.017 14.1 0.0 0.42 9.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 EIM87695.1 - 0.043 12.7 0.1 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mob1_phocein PF03637.12 EIM87696.1 - 4e-25 88.4 0.0 6.8e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family Amidase PF01425.16 EIM87697.1 - 2.9e-80 270.3 0.0 3.5e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Kinetochor_Ybp2 PF08568.5 EIM87698.1 - 5.2e-17 61.3 0.0 2e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin PKD PF00801.15 EIM87699.1 - 0.75 9.5 7.8 4.1 7.2 1.3 2.9 1 1 1 2 2 2 0 PKD domain Pkinase PF00069.20 EIM87700.1 - 4.1e-40 137.5 0.0 1.2e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87700.1 - 1e-22 80.4 0.0 1.4e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EIM87701.1 - 4.5e-24 84.8 38.1 7.6e-24 84.0 26.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.6 EIM87701.1 - 0.19 11.3 0.8 0.53 9.8 0.5 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Amidohydro_1 PF01979.15 EIM87702.1 - 1.5e-35 123.4 2.1 1.8e-35 123.1 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM87702.1 - 1.3e-14 53.6 0.1 5.1e-14 51.8 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIM87702.1 - 1.6e-10 41.4 0.0 4.2e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM87702.1 - 8.1e-06 25.2 3.4 0.00016 21.0 0.2 2.3 1 1 1 2 2 2 2 Amidohydrolase family Ephrin_lbd PF01404.14 EIM87703.1 - 0.035 13.9 1.0 0.066 13.0 0.4 1.6 1 1 1 2 2 2 0 Ephrin receptor ligand binding domain COesterase PF00135.23 EIM87704.1 - 8.3e-81 272.3 0.0 9e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM87704.1 - 1.3e-06 28.0 0.3 7.3e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM87704.1 - 0.00027 20.7 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family GST_N_3 PF13417.1 EIM87705.1 - 2.7e-20 72.3 0.0 4.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM87705.1 - 1.7e-12 47.1 0.0 3.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM87705.1 - 0.00024 20.9 0.3 0.0028 17.4 0.2 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM87705.1 - 0.00079 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EIM87705.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Peroxin-13_N PF04088.8 EIM87706.1 - 2.5e-39 134.7 0.0 4.4e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 EIM87706.1 - 2.8e-10 39.4 2.8 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIM87706.1 - 1.7e-09 37.0 0.1 3.1e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIM87706.1 - 2.6e-08 33.3 2.6 1.6e-07 30.8 1.8 2.1 1 1 0 1 1 1 1 Variant SH3 domain Gti1_Pac2 PF09729.4 EIM87709.1 - 8.9e-11 41.9 4.3 4.2e-09 36.4 0.3 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family SOG2 PF10428.4 EIM87709.1 - 0.0011 17.7 2.1 0.0013 17.5 1.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein DUF3395 PF11875.3 EIM87710.1 - 9.6e-29 99.9 0.0 1.8e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EIM87710.1 - 9.5e-18 63.7 1.0 1.5e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4381 PF14316.1 EIM87710.1 - 0.00023 21.3 0.1 0.00052 20.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DCP1 PF06058.8 EIM87711.1 - 1.3e-18 67.1 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family DUF1706 PF08020.6 EIM87711.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) BLVR PF06375.6 EIM87711.1 - 0.16 11.8 6.5 0.053 13.3 2.4 1.8 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Glyco_transf_28 PF03033.15 EIM87712.1 - 7.1e-24 84.1 0.0 2.7e-22 79.0 0.0 2.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EIM87712.1 - 4.3e-05 22.2 0.0 7.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EIM87712.1 - 0.00011 22.3 0.0 0.0031 17.6 0.0 3.0 3 0 0 3 3 3 1 ATG C terminal domain RNase_H PF00075.19 EIM87713.1 - 2.9e-08 34.1 0.2 4.1e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 RNase H MdoG PF04349.7 EIM87713.1 - 0.12 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Sec5 PF15469.1 EIM87714.1 - 2.3e-57 193.6 0.1 8.7e-57 191.7 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EIM87714.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 PHD PF00628.24 EIM87715.1 - 0.0015 18.1 2.3 0.0015 18.1 1.6 2.7 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.1 EIM87715.1 - 0.0052 16.9 2.6 0.015 15.3 0.1 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EIM87715.1 - 0.035 13.8 1.2 0.15 11.8 0.8 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 EIM87715.1 - 0.12 12.3 2.5 0.27 11.2 0.1 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain MULE PF10551.4 EIM87717.1 - 6.1e-05 23.1 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 EIM87717.1 - 0.00065 19.1 1.4 0.0015 17.9 0.9 1.6 1 0 0 1 1 1 1 SWIM zinc finger Retrotrans_gag PF03732.12 EIM87721.1 - 2.6e-12 46.6 0.1 7.6e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein UMP1 PF05348.6 EIM87722.1 - 0.0013 18.6 0.1 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 NTP_transf_2 PF01909.18 EIM87723.1 - 2.3e-05 24.6 0.0 5.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain SH3_9 PF14604.1 EIM87724.1 - 7.8e-16 57.3 0.2 2.1e-15 55.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.24 EIM87724.1 - 1.3e-13 51.0 0.2 3e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EIM87724.1 - 1.4e-12 47.2 0.0 2.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIM87724.1 - 3.1e-12 45.6 0.2 6.5e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIM87724.1 - 2.9e-09 36.2 0.1 5.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EIM87724.1 - 3.5e-09 36.6 0.4 6.8e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EIM87724.1 - 0.0025 18.0 0.6 0.0087 16.2 0.4 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 EIM87724.1 - 0.011 15.7 0.2 0.023 14.7 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Mito_carr PF00153.22 EIM87725.1 - 1.1e-51 172.4 4.1 1.1e-17 63.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Phosducin PF02114.11 EIM87726.1 - 2.9e-18 65.5 0.0 2.1e-08 33.2 0.0 3.1 3 0 0 3 3 3 3 Phosducin HNH_2 PF13391.1 EIM87727.1 - 0.0054 16.4 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease Pyridoxal_deC PF00282.14 EIM87728.1 - 1.1e-17 63.5 0.0 8.3e-10 37.6 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Herpes_gE PF02480.11 EIM87729.1 - 0.0015 16.8 0.1 0.0021 16.3 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EIM87729.1 - 0.0037 16.1 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) MGC-24 PF05283.6 EIM87729.1 - 0.0039 16.9 10.8 0.0082 15.9 7.5 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Syndecan PF01034.15 EIM87729.1 - 0.0096 15.5 1.6 0.017 14.7 1.1 1.3 1 0 0 1 1 1 1 Syndecan domain Pex14_N PF04695.8 EIM87729.1 - 0.011 15.7 1.9 0.022 14.7 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mid2 PF04478.7 EIM87729.1 - 0.012 15.0 3.1 0.018 14.4 2.2 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EIM87729.1 - 0.024 14.1 2.3 0.041 13.4 1.6 1.3 1 0 0 1 1 1 0 Podoplanin Alpha_GJ PF03229.8 EIM87729.1 - 0.055 13.8 9.7 0.053 13.8 5.9 1.5 1 1 0 1 1 1 0 Alphavirus glycoprotein J DUF1517 PF07466.6 EIM87729.1 - 0.07 12.1 1.1 0.095 11.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TMEM154 PF15102.1 EIM87729.1 - 0.27 10.9 4.5 0.21 11.3 2.0 1.6 1 1 1 2 2 2 0 TMEM154 protein family SSP160 PF06933.6 EIM87729.1 - 7.9 4.3 18.2 11 3.8 12.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 EIM87730.1 - 8.8e-30 103.6 18.1 8.8e-30 103.6 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM87730.1 - 9.3e-08 30.8 11.7 1.8e-05 23.3 0.0 3.8 3 1 1 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.19 EIM87730.1 - 0.00018 20.2 16.5 0.002 16.7 1.7 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter Cys_Met_Meta_PP PF01053.15 EIM87732.1 - 1.8e-16 59.4 0.0 9.6e-14 50.4 0.0 2.7 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIM87732.1 - 1.4e-08 34.0 0.0 2.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIM87733.1 - 0.00059 18.2 0.0 0.0025 16.1 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Trp_halogenase PF04820.9 EIM87734.1 - 1.1e-26 93.5 0.6 1.1e-16 60.5 0.0 3.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EIM87734.1 - 1.8e-07 30.5 0.3 0.045 12.8 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM87734.1 - 5.7e-05 22.1 0.0 0.26 10.1 0.0 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM87734.1 - 0.016 15.2 0.1 0.074 13.0 0.1 2.2 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EIM87736.1 - 2.2e-17 62.8 28.6 2.2e-17 62.8 19.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87736.1 - 1.6e-09 36.8 1.5 4e-09 35.5 1.1 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIM87736.1 - 0.0007 17.9 0.1 0.0013 17.0 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4551 PF15087.1 EIM87738.1 - 0.15 10.3 0.3 0.27 9.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HMG_box PF00505.14 EIM87740.1 - 8.5e-12 45.1 0.4 9.9e-06 25.7 0.0 2.4 1 1 1 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM87740.1 - 5.4e-11 42.7 0.5 0.00014 22.1 0.1 2.3 1 1 1 2 2 2 2 HMG-box domain DUF1289 PF06945.8 EIM87740.1 - 7.1 6.1 7.2 10 5.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) HMG_box_2 PF09011.5 EIM87742.1 - 3.1e-05 24.2 0.5 3.6e-05 24.0 0.4 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EIM87742.1 - 4.5e-05 23.6 0.3 9.1e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box PF00505.14 EIM87743.1 - 0.035 14.3 1.6 5.1 7.4 0.0 3.3 2 1 0 3 3 3 0 HMG (high mobility group) box DUF1289 PF06945.8 EIM87743.1 - 0.16 11.4 0.6 4.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF3328 PF11807.3 EIM87744.1 - 2.7e-14 53.3 0.4 1.3e-13 51.1 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EIM87745.1 - 6.1e-18 65.2 0.2 1.3e-17 64.1 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 EIM87746.1 - 0.077 12.7 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain Dickkopf_N PF04706.7 EIM87749.1 - 0.0015 18.6 4.1 0.0017 18.4 2.8 1.1 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Toxin_12 PF07740.7 EIM87749.1 - 0.0072 16.7 6.1 0.012 16.1 4.2 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin LEAP-2 PF07359.6 EIM87749.1 - 0.013 15.1 0.5 0.014 15.0 0.3 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Conotoxin PF02950.12 EIM87749.1 - 0.022 15.5 6.1 0.022 15.5 4.2 1.7 1 1 1 2 2 2 0 Conotoxin Toxin_19 PF08088.7 EIM87749.1 - 0.034 14.0 5.2 0.042 13.7 3.6 1.2 1 0 0 1 1 1 0 Conotoxin I-superfamily Agouti PF05039.7 EIM87749.1 - 0.043 14.1 2.8 0.044 14.1 1.9 1.1 1 0 0 1 1 1 0 Agouti protein Toxin_27 PF08099.6 EIM87749.1 - 2.9 7.8 7.0 2.1 8.3 3.8 1.5 1 1 1 2 2 2 0 Scorpion calcine family Rab5ip PF07019.7 EIM87750.1 - 9.7e-15 54.4 2.7 1.2e-14 54.1 1.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2127 PF09900.4 EIM87750.1 - 0.026 14.5 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF3367 PF11847.3 EIM87750.1 - 0.045 11.6 0.2 0.053 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) VIT_2 PF13757.1 EIM87751.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Toxin_27 PF08099.6 EIM87751.1 - 0.33 10.8 5.5 0.6 10.0 3.8 1.4 1 0 0 1 1 1 0 Scorpion calcine family Toxin_12 PF07740.7 EIM87751.1 - 1.3 9.6 9.1 0.37 11.3 4.0 1.9 2 0 0 2 2 2 0 Ion channel inhibitory toxin TPR_11 PF13414.1 EIM87754.1 - 9.7e-18 63.5 3.8 3.4e-12 45.8 1.5 4.4 3 2 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EIM87754.1 - 1.6e-15 55.6 1.5 0.00084 19.0 0.5 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87754.1 - 3.4e-10 39.1 2.8 0.00023 20.6 0.3 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87754.1 - 3.9e-06 26.7 2.5 0.0094 15.8 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM87754.1 - 0.0029 17.2 1.1 2.5 8.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EIM87754.1 - 0.013 15.3 0.4 0.03 14.1 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 EIM87754.1 - 0.013 16.0 6.1 1.3 9.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIM87754.1 - 0.021 14.9 0.6 0.18 12.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4033 PF13225.1 EIM87754.1 - 0.051 13.2 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) TPR_16 PF13432.1 EIM87754.1 - 0.082 13.6 9.0 0.064 13.9 1.1 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM87754.1 - 0.099 12.4 0.7 3.9 7.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.13 EIM87755.1 - 7.9e-37 126.8 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EIM87755.1 - 4.5e-29 101.2 0.0 7.4e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EIM87755.1 - 0.038 14.5 0.2 0.098 13.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EIM87755.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EIM87755.1 - 0.08 12.9 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 EIM87761.1 - 4.2e-38 130.9 32.4 4.2e-38 130.9 22.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM87761.1 - 2.5e-05 23.0 29.3 5.7e-05 21.8 20.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.19 EIM87762.1 - 3.1e-39 134.8 0.0 5.2e-39 134.1 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM87762.1 - 8.9e-09 35.5 0.0 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM87762.1 - 1.5e-06 28.1 0.1 4e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM87762.1 - 5e-06 26.7 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM87762.1 - 7.6e-06 25.1 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EIM87762.1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIM87762.1 - 3e-05 23.0 0.1 0.0027 16.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIM87762.1 - 4.4e-05 22.4 0.2 0.00017 20.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM87762.1 - 0.0003 19.3 0.0 0.029 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 EIM87762.1 - 0.00095 19.3 0.0 0.0036 17.5 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GMC_oxred_N PF00732.14 EIM87762.1 - 0.0011 18.2 0.0 0.0053 15.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.22 EIM87762.1 - 0.0015 18.9 0.1 0.0074 16.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM87762.1 - 0.0032 16.6 0.0 0.31 10.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EIM87762.1 - 0.0036 17.4 0.1 0.036 14.1 0.2 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIM87762.1 - 0.0098 15.6 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.11 EIM87762.1 - 0.012 15.0 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIM87762.1 - 0.015 13.9 0.5 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EIM87762.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EIM87762.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIM87762.1 - 0.05 12.7 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM87762.1 - 0.052 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIM87762.1 - 0.069 12.0 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EIM87762.1 - 0.16 11.3 0.3 0.88 8.9 0.1 2.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UBN2_2 PF14227.1 EIM87763.1 - 0.00031 20.2 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EIM87763.1 - 0.0011 18.7 1.3 0.0019 18.0 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EIM87763.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.1 EIM87763.1 - 0.095 12.3 0.3 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIM87763.1 - 0.12 12.1 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle 2-Hacid_dh_C PF02826.14 EIM87767.1 - 1.2e-53 180.8 0.0 1.6e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM87767.1 - 6.2e-13 48.3 0.0 8.1e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM87767.1 - 3.4e-05 23.7 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 EIM87767.1 - 0.036 14.3 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 EIM87767.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIM87767.1 - 0.12 12.2 0.2 0.88 9.4 0.0 2.3 2 1 0 2 2 2 0 short chain dehydrogenase TPR_11 PF13414.1 EIM87768.1 - 3.8e-18 64.9 1.1 7.8e-07 28.6 0.0 6.1 6 1 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 EIM87768.1 - 6.7e-12 44.3 13.7 0.0039 16.9 0.0 7.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIM87768.1 - 8.1e-12 44.2 0.3 1.2 8.8 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM87768.1 - 1.7e-10 40.7 1.8 0.00073 19.4 0.0 6.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM87768.1 - 3.3e-06 26.8 0.0 0.0087 16.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM87768.1 - 1.3e-05 24.6 7.9 0.43 10.5 0.0 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM87768.1 - 2.1e-05 25.0 7.1 0.0035 17.9 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM87768.1 - 6.2e-05 23.2 17.5 0.54 11.0 0.0 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM87768.1 - 0.00035 20.3 7.9 0.0018 18.1 0.1 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM87768.1 - 0.0038 17.5 0.8 54 4.5 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat dsrm PF00035.20 EIM87771.1 - 9.6e-13 48.5 0.1 7.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Double-stranded RNA binding motif GPI-anchored PF10342.4 EIM87771.1 - 0.11 13.0 0.5 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family dsrm PF00035.20 EIM87772.1 - 5.5e-17 62.1 0.0 3.9e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif dsrm PF00035.20 EIM87773.1 - 1.9e-12 47.5 0.0 4.8e-07 30.2 0.0 2.9 3 0 0 3 3 3 2 Double-stranded RNA binding motif Nucleoplasmin PF03066.10 EIM87774.1 - 0.23 10.9 8.1 0.5 9.8 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EIM87774.1 - 2 6.2 9.5 4.6 5.0 6.6 1.5 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 EIM87774.1 - 4.3 5.5 12.0 7.7 4.7 8.3 1.3 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 EIM87774.1 - 9.1 5.4 8.1 19 4.4 5.6 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EIM87774.1 - 9.8 5.7 10.1 28 4.2 7.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region H2TH PF06831.9 EIM87776.1 - 0.00032 20.3 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain WD40 PF00400.27 EIM87778.1 - 1e-64 212.2 10.5 1e-13 50.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat NACHT PF05729.7 EIM87778.1 - 8.3e-07 28.8 0.0 3.1e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 NACHT domain Cytochrom_D1 PF02239.11 EIM87778.1 - 1.1e-06 27.2 2.0 0.0021 16.4 0.2 2.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 EIM87778.1 - 1.2e-06 27.4 0.0 0.094 11.3 0.0 3.4 3 0 0 3 3 3 3 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.1 EIM87778.1 - 2e-06 27.4 6.3 5.5e-06 26.0 4.3 1.8 1 0 0 1 1 1 1 PQQ-like domain DUF3312 PF11768.3 EIM87778.1 - 1.8e-05 23.2 0.2 0.29 9.3 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF3312) AAA_16 PF13191.1 EIM87778.1 - 3.7e-05 23.7 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.1 EIM87778.1 - 0.0019 18.3 6.3 7.5 6.9 0.3 5.1 5 1 0 5 5 4 1 PQQ-like domain NB-ARC PF00931.17 EIM87778.1 - 0.0041 16.0 0.0 0.012 14.4 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EIM87778.1 - 0.0073 16.4 0.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain PD40 PF07676.7 EIM87778.1 - 0.0074 15.9 4.6 53 3.6 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 EIM87778.1 - 0.012 15.7 0.0 0.061 13.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EIM87778.1 - 0.037 14.2 0.1 0.33 11.1 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EIM87778.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Rab5ip PF07019.7 EIM87779.1 - 4.8e-14 52.2 3.6 6.2e-14 51.9 2.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3367 PF11847.3 EIM87779.1 - 0.067 11.1 0.2 0.077 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) F-box-like PF12937.2 EIM87781.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like PLU-1 PF08429.6 EIM87783.1 - 1.1e-42 146.1 0.8 3.3e-41 141.3 0.3 3.1 2 1 1 3 3 3 1 PLU-1-like protein JmjC PF02373.17 EIM87783.1 - 8.3e-41 138.8 0.2 2.5e-40 137.2 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EIM87783.1 - 3.5e-20 71.6 0.1 1.1e-19 70.0 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EIM87783.1 - 1.7e-16 59.4 1.1 3.4e-16 58.4 0.8 1.5 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EIM87783.1 - 6.5e-16 57.7 42.1 1.9e-11 43.4 5.3 4.4 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 EIM87783.1 - 7.5e-15 54.7 11.6 7.5e-15 54.7 8.0 2.2 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 EIM87783.1 - 0.00068 19.3 5.9 0.00068 19.3 4.1 4.1 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EIM87783.1 - 0.057 12.7 19.2 0.18 11.1 0.7 3.8 3 0 0 3 3 3 0 PHD-finger 14-3-3 PF00244.15 EIM87784.1 - 3.4e-118 392.9 4.0 3.9e-118 392.7 2.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EIM87784.1 - 0.044 13.3 3.2 1.1 8.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) HisKA PF00512.20 EIM87784.1 - 0.11 12.4 0.8 2.4 8.2 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_19 PF14559.1 EIM87784.1 - 0.17 12.2 1.5 2.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 EIM87787.1 - 4.7e-09 35.8 0.3 1.5e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like Bac_rhamnosid PF05592.6 EIM87788.1 - 3e-38 131.3 0.2 2.8e-37 128.1 0.1 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EIM87788.1 - 3.9e-05 22.5 1.0 7.3e-05 21.6 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 EIM87788.1 - 0.0032 16.1 0.2 0.0047 15.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase F-box-like PF12937.2 EIM87789.1 - 0.064 12.9 0.0 0.43 10.3 0.0 2.4 2 1 0 2 2 2 0 F-box-like MscS_porin PF12795.2 EIM87789.1 - 0.086 12.1 2.8 0.14 11.4 1.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sedlin_N PF04628.8 EIM87790.1 - 3.2e-24 85.2 0.0 3.7e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region F-box-like PF12937.2 EIM87791.1 - 0.00022 20.8 0.4 0.00078 19.1 0.3 2.1 1 1 0 1 1 1 1 F-box-like DUF2435 PF10363.4 EIM87792.1 - 9.6e-28 95.9 0.4 7.6e-26 89.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EIM87792.1 - 0.0026 17.6 3.1 0.68 10.1 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat DUF2411 PF10304.4 EIM87792.1 - 0.074 12.6 2.8 0.1 12.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) Saccharop_dh PF03435.13 EIM87793.1 - 9.6e-104 347.4 0.0 1.1e-103 347.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIM87793.1 - 2.8e-05 24.2 0.1 9.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2325 PF10087.4 EIM87793.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Saccharop_dh PF03435.13 EIM87794.1 - 1.2e-107 360.2 0.1 3.7e-107 358.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EIM87794.1 - 3.6e-92 307.7 0.0 6.1e-92 307.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 EIM87794.1 - 1.6e-06 28.2 0.3 6.9e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EIM87794.1 - 0.00055 20.4 0.0 0.0023 18.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM87794.1 - 0.0019 18.6 0.0 0.0097 16.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIM87794.1 - 0.041 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF43 PF01861.11 EIM87794.1 - 0.044 12.7 0.1 0.099 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF43 DREV PF05219.7 EIM87794.1 - 0.056 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase CtaG_Cox11 PF04442.9 EIM87795.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 TENA_THI-4 PF03070.11 EIM87796.1 - 2.8e-12 46.8 0.2 6.1e-12 45.7 0.2 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family RraB PF06877.6 EIM87796.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Cu-oxidase PF00394.17 EIM87797.1 - 7.3e-50 168.9 0.1 7.2e-46 155.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM87797.1 - 1.8e-39 134.3 0.2 8.3e-35 119.2 0.1 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM87797.1 - 1.1e-36 125.1 0.6 7.5e-32 109.5 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase IcmL PF11393.3 EIM87798.1 - 0.14 12.0 1.2 0.43 10.5 0.2 1.9 1 1 1 2 2 2 0 Macrophage killing protein with similarity to conjugation protein DUF4653 PF15546.1 EIM87798.1 - 1.6 7.9 3.8 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RTA1 PF04479.8 EIM87799.1 - 6e-37 127.2 1.8 8.7e-37 126.7 1.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4186 PF13811.1 EIM87800.1 - 0.03 14.0 0.7 2.3 7.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4186) Herpes_UL16 PF03044.9 EIM87800.1 - 0.069 12.1 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family VWA_2 PF13519.1 EIM87801.1 - 7.3e-09 35.9 0.0 4.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain RHD3 PF05879.7 EIM87801.1 - 8.8e-08 30.5 0.2 1.4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA PF00092.23 EIM87801.1 - 5.1e-06 26.3 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.14 EIM87801.1 - 3.3e-05 23.0 0.1 3.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain zf-RING_2 PF13639.1 EIM87802.1 - 7e-08 32.1 9.2 7e-08 32.1 6.4 3.6 3 1 0 3 3 3 1 Ring finger domain IBR PF01485.16 EIM87802.1 - 2e-07 30.7 6.0 2e-07 30.7 4.1 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EIM87802.1 - 4.7e-05 23.3 9.6 4.7e-05 23.3 6.7 5.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM87802.1 - 0.00012 21.6 7.9 0.00012 21.6 5.5 4.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM87802.1 - 0.00014 21.5 7.7 0.00014 21.5 5.3 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-MIZ PF02891.15 EIM87802.1 - 0.0047 16.4 5.3 0.0047 16.4 3.7 4.3 2 1 1 3 3 3 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EIM87802.1 - 0.017 14.8 1.2 0.017 14.8 0.8 3.9 3 2 1 4 4 4 0 RING-type zinc-finger IR1-M PF12185.3 EIM87802.1 - 0.1 12.3 0.3 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Rad50_zn_hook PF04423.9 EIM87802.1 - 3.6 7.1 7.0 20 4.7 0.0 3.7 3 1 0 3 3 3 0 Rad50 zinc hook motif MOSC_N PF03476.11 EIM87803.1 - 6.9e-20 70.9 0.0 1.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EIM87803.1 - 6.4e-08 32.1 0.0 2.2e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 MOSC domain DUF605 PF04652.11 EIM87804.1 - 4.1 6.7 19.2 5.2 6.3 13.3 1.1 1 0 0 1 1 1 0 Vta1 like 14-3-3 PF00244.15 EIM87805.1 - 6.9e-60 202.0 1.0 1.3e-56 191.2 1.1 2.0 2 0 0 2 2 2 2 14-3-3 protein Gp49 PF05973.9 EIM87805.1 - 0.043 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) DUF4317 PF14199.1 EIM87805.1 - 0.088 11.5 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) DUF4252 PF14060.1 EIM87805.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Aminotran_1_2 PF00155.16 EIM87806.1 - 1.3e-11 44.0 0.0 1e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Dioxygenase_C PF00775.16 EIM87807.1 - 5e-48 162.7 0.0 6.9e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIM87807.1 - 3.1e-15 55.8 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus T2SI PF02501.12 EIM87807.1 - 0.11 12.5 0.8 0.22 11.5 0.5 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I zf-CCHC PF00098.18 EIM87809.1 - 3.5e-32 108.7 49.7 9.4e-07 28.4 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 EIM87809.1 - 1.5e-08 34.1 35.3 0.0091 15.6 0.6 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EIM87809.1 - 0.00082 18.9 38.7 0.0067 16.0 1.7 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.1 EIM87809.1 - 0.044 13.2 0.3 0.044 13.2 0.2 4.9 4 1 2 6 6 6 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EIM87809.1 - 0.067 12.9 37.8 4.1 7.2 0.0 6.1 3 1 2 5 5 5 0 Zinc knuckle CorA PF01544.13 EIM87810.1 - 5.8e-48 163.4 0.5 8.2e-48 162.9 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein A_thal_3526 PF09713.5 EIM87810.1 - 0.012 15.6 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Baculo_PEP_C PF04513.7 EIM87810.1 - 0.027 14.3 0.6 0.056 13.2 0.3 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 EIM87810.1 - 0.067 12.8 0.4 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) ACT_4 PF13291.1 EIM87810.1 - 0.11 12.7 0.1 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 ACT domain DUF4401 PF14351.1 EIM87811.1 - 0.017 14.0 3.8 0.066 12.1 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF3112 PF11309.3 EIM87812.1 - 0.002 17.9 1.7 0.0047 16.7 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3112) Cyto_ox_2 PF02322.10 EIM87812.1 - 0.18 10.9 4.8 0.23 10.5 3.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF4131 PF13567.1 EIM87812.1 - 0.19 11.1 2.8 0.28 10.5 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4234 PF14018.1 EIM87812.1 - 0.39 10.4 2.8 0.47 10.2 0.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) AAA_12 PF13087.1 EIM87813.1 - 3.5e-32 111.4 0.1 9.1e-32 110.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM87813.1 - 4.4e-13 49.3 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIM87813.1 - 7.7e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Polyketide_cyc PF03364.15 EIM87814.1 - 1.5e-18 67.0 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Opi1 PF08618.5 EIM87817.1 - 0.038 12.9 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 CHAT PF12770.2 EIM87818.1 - 1.4e-42 145.8 0.0 1.8e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Ndc1_Nup PF09531.5 EIM87820.1 - 1.6 7.0 15.5 2.6 6.3 10.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec7 PF01369.15 EIM87821.1 - 4.7e-63 212.3 0.1 1.1e-62 211.0 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIM87821.1 - 1.8e-49 167.3 4.3 1.8e-49 167.3 3.0 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIM87821.1 - 5.1e-31 106.0 0.9 5.1e-31 106.0 0.6 4.4 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 EIM87821.1 - 0.0098 15.9 0.0 12 6.2 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat DS PF01916.12 EIM87822.1 - 9.9e-135 448.4 0.0 1.1e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DAO PF01266.19 EIM87823.1 - 3.9e-30 104.9 0.1 1.4e-29 103.0 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM87823.1 - 0.018 15.0 0.4 0.056 13.4 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain BTB PF00651.26 EIM87824.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM87825.1 - 6.9e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM87826.1 - 0.00018 21.4 0.1 0.0081 16.1 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain SH3_9 PF14604.1 EIM87827.1 - 3.3e-37 125.8 10.2 3.7e-13 48.8 0.5 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 EIM87827.1 - 4.8e-37 125.1 9.9 3.6e-17 61.4 0.5 4.1 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 EIM87827.1 - 2.6e-29 100.4 0.1 3e-09 36.2 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SHD1 PF03983.7 EIM87827.1 - 1.2e-24 85.7 0.0 2.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_3 PF08239.6 EIM87827.1 - 0.00026 21.0 4.4 4.4 7.5 0.6 3.6 3 0 0 3 3 3 3 Bacterial SH3 domain Asp-B-Hydro_N PF05279.6 EIM87827.1 - 0.43 10.3 27.1 1.1 9.1 18.8 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.2 EIM87827.1 - 2.1 5.9 9.5 3.1 5.3 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTB PF00651.26 EIM87828.1 - 1.7e-05 24.7 0.1 0.00045 20.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIM87829.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain PXB PF12828.2 EIM87829.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 1 1 2 2 2 0 PX-associated PCI PF01399.22 EIM87830.1 - 4.2e-11 43.1 0.0 1.8e-10 41.0 0.0 2.1 3 0 0 3 3 3 1 PCI domain Peptidase_M24 PF00557.19 EIM87833.1 - 1.8e-44 151.8 0.0 2.2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EIM87833.1 - 1.1 9.1 9.4 2.7 7.9 6.5 1.7 1 0 0 1 1 1 0 MYND finger Nucleoplasmin PF03066.10 EIM87834.1 - 4.7 6.7 8.5 0.28 10.6 2.1 1.7 2 0 0 2 2 2 0 Nucleoplasmin CHAT PF12770.2 EIM87835.1 - 3.9e-33 114.8 0.0 5.8e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 CHAT domain DUF1793 PF08760.6 EIM87836.1 - 2.3e-60 203.3 0.3 5.5e-60 202.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EIM87836.1 - 0.00031 19.1 0.2 0.00053 18.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Atg31 PF09795.4 EIM87836.1 - 0.15 11.7 0.1 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 31 zf-C2H2 PF00096.21 EIM87837.1 - 1.3e-24 84.9 59.9 0.0036 17.5 0.2 10.6 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM87837.1 - 9.8e-15 53.7 56.7 0.12 12.7 0.6 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM87837.1 - 2.2e-13 49.7 58.0 1.5e-05 25.0 1.4 11.0 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM87837.1 - 0.002 18.2 24.3 1.6 8.9 0.0 7.4 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM87837.1 - 0.071 13.3 24.8 0.32 11.2 1.9 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIM87837.1 - 1.4 8.8 15.9 5.3 7.1 0.1 5.0 6 0 0 6 6 6 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIM87837.1 - 3.4 8.0 0.0 3.4 8.0 0.0 7.6 10 0 0 10 10 10 0 C2H2-type zinc-finger domain ORMDL PF04061.9 EIM87839.1 - 1.3e-47 160.7 3.4 1.9e-47 160.2 2.3 1.2 1 0 0 1 1 1 1 ORMDL family DUF2404 PF10296.4 EIM87841.1 - 7.6e-07 29.1 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF2938 PF11158.3 EIM87843.1 - 0.063 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) DUF2009 PF09418.5 EIM87844.1 - 3.1e-201 669.1 0.1 3.6e-201 668.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EIM87844.1 - 5.4e-05 22.9 7.9 0.0001 22.0 5.5 1.4 1 0 0 1 1 1 1 B-box zinc finger 4HB_MCP_1 PF12729.2 EIM87844.1 - 0.024 13.9 0.3 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction IBR PF01485.16 EIM87844.1 - 0.14 12.0 6.9 0.31 10.9 4.8 1.5 1 0 0 1 1 1 0 IBR domain DUF1793 PF08760.6 EIM87845.1 - 2.7e-53 180.3 0.9 6.3e-53 179.1 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EIM87845.1 - 0.00013 20.3 0.2 0.00022 19.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Atg31 PF09795.4 EIM87845.1 - 0.012 15.3 0.1 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 31 DUF3661 PF12400.3 EIM87847.1 - 4.6e-38 130.2 5.3 6.7e-38 129.6 3.7 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF3328 PF11807.3 EIM87848.1 - 1.7 8.2 7.7 6.7 6.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) GTP_EFTU PF00009.22 EIM87849.1 - 1.2e-46 158.4 0.0 1.9e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIM87849.1 - 4e-27 94.2 0.1 2.1e-25 88.7 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIM87849.1 - 8.4e-10 38.6 2.2 1.3e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM87849.1 - 0.00041 20.2 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_3_C PF01915.17 EIM87849.1 - 0.017 14.6 0.1 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain ApoA-II PF04711.8 EIM87849.1 - 0.089 12.6 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Peptidase_S28 PF05577.7 EIM87851.1 - 1.4e-47 162.3 0.1 3.5e-47 160.9 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EIM87851.1 - 0.0016 18.3 0.2 0.0038 17.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM87851.1 - 0.029 13.5 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family THF_DHG_CYH_C PF02882.14 EIM87852.1 - 1.7e-19 69.4 0.1 1.3e-08 34.0 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIM87852.1 - 1.2e-12 47.8 0.0 2.6e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 EIM87852.1 - 0.0016 18.5 0.1 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIM87852.1 - 0.01 16.1 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RRS1 PF04939.7 EIM87853.1 - 4.1e-52 175.9 0.9 6.3e-52 175.3 0.6 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TFIIB PF00382.14 EIM87854.1 - 1.5e-33 114.3 0.0 6.5e-21 73.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EIM87854.1 - 7e-12 44.4 1.5 1.3e-11 43.6 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_23 PF13384.1 EIM87854.1 - 0.015 14.9 0.0 0.3 10.8 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r4 PF04545.11 EIM87854.1 - 0.017 14.3 0.0 0.16 11.3 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_28 PF13518.1 EIM87854.1 - 0.022 14.7 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Cyclin_C PF02984.14 EIM87854.1 - 0.03 14.2 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain UNC45-central PF11701.3 EIM87854.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Cyclin_N PF00134.18 EIM87854.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HTH_5 PF01022.15 EIM87854.1 - 0.15 11.7 0.1 37 4.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Uds1 PF15456.1 EIM87855.1 - 3.6e-33 114.1 12.5 3.6e-33 114.1 8.7 6.1 3 2 1 5 5 5 1 Up-regulated During Septation Snapin_Pallidin PF14712.1 EIM87855.1 - 0.0043 17.3 4.1 0.0043 17.3 2.8 5.7 5 2 1 6 6 6 1 Snapin/Pallidin DUF2064 PF09837.4 EIM87855.1 - 0.022 14.3 2.8 0.032 13.8 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF948 PF06103.6 EIM87855.1 - 1.3 8.8 12.6 1.3 8.9 0.9 4.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RecO_N PF11967.3 EIM87858.1 - 0.049 13.4 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O N terminal TMCO5 PF14992.1 EIM87858.1 - 0.051 12.7 0.9 0.064 12.3 0.6 1.1 1 0 0 1 1 1 0 TMCO5 family Laminin_II PF06009.7 EIM87858.1 - 0.22 11.2 0.9 11 5.7 0.1 2.2 1 1 1 2 2 2 0 Laminin Domain II DGF-1_C PF11040.3 EIM87858.1 - 0.42 10.5 5.5 3.7 7.5 3.8 2.4 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SNF2_assoc PF08455.5 EIM87859.1 - 0.0065 15.0 0.0 0.0093 14.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated IATP PF04568.7 EIM87860.1 - 0.5 10.4 2.0 0.92 9.5 1.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP zf-RING_2 PF13639.1 EIM87862.1 - 4.6e-09 35.9 4.3 3.2e-08 33.2 1.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIM87862.1 - 8.1e-07 29.0 1.2 1.6e-06 28.1 0.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIM87862.1 - 6.5e-05 22.5 0.7 6.5e-05 22.5 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM87862.1 - 0.00018 21.1 0.4 0.00037 20.1 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM87862.1 - 0.00045 19.8 2.0 0.00045 19.8 1.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM87862.1 - 0.00075 19.4 3.3 0.00075 19.4 2.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM87862.1 - 0.001 18.8 0.6 0.0023 17.7 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIM87862.1 - 0.25 10.9 1.8 0.51 9.9 1.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EIM87862.1 - 0.26 10.8 3.6 0.56 9.7 2.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger RINGv PF12906.2 EIM87862.1 - 0.88 9.6 4.2 1.9 8.5 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain Nnf1 PF03980.9 EIM87863.1 - 5.8e-08 32.6 0.1 1.1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Nnf1 NTR2 PF15458.1 EIM87863.1 - 0.0042 16.3 0.3 0.0042 16.3 0.2 1.5 2 0 0 2 2 2 1 Nineteen complex-related protein 2 DUF3131 PF11329.3 EIM87863.1 - 0.014 14.1 0.0 0.47 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3131) Herpes_BLRF2 PF05812.7 EIM87863.1 - 0.082 12.7 2.6 0.19 11.5 1.8 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein APG6 PF04111.7 EIM87863.1 - 0.24 10.3 3.1 0.34 9.8 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Med21 PF11221.3 EIM87863.1 - 9.5 6.1 6.8 11 5.9 1.8 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Glyco_hydro_53 PF07745.8 EIM87864.1 - 7.8e-79 264.8 0.0 8.9e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 tRNA-synt_2e PF02091.10 EIM87864.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit GMC_oxred_N PF00732.14 EIM87865.1 - 7.3e-55 186.2 0.0 1.1e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87865.1 - 5.9e-26 91.4 0.0 1.2e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM87865.1 - 0.0029 16.5 0.7 0.089 11.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM87865.1 - 0.0053 15.6 0.8 1.3 7.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EIM87865.1 - 0.0079 15.1 0.2 0.012 14.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIM87865.1 - 0.11 11.5 0.4 0.26 10.3 0.3 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIM87865.1 - 0.15 10.7 0.1 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 EIM87866.1 - 3.3e-56 190.6 0.0 5.4e-56 189.9 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87866.1 - 1.8e-32 112.5 0.0 3e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM87866.1 - 0.00032 19.7 0.1 0.00046 19.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EIM87866.1 - 0.00049 19.1 0.1 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM87866.1 - 0.0057 15.5 0.1 0.66 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM87866.1 - 0.038 14.0 0.1 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IPP-2 PF04979.9 EIM87868.1 - 1.2e-14 54.6 5.4 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF566 PF04484.7 EIM87868.1 - 0.68 9.3 5.0 1.1 8.7 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pro-kuma_activ PF09286.6 EIM87870.1 - 2.5e-39 134.5 0.0 4.1e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM87870.1 - 8.8e-09 34.9 0.9 8.8e-09 34.9 0.6 1.5 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 EIM87871.1 - 4.6e-41 140.1 0.1 9.1e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM87871.1 - 8.6e-05 21.8 0.0 0.00018 20.7 0.0 1.7 1 1 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 EIM87873.1 - 1.3e-37 128.9 0.0 2.4e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM87873.1 - 9.4e-08 31.5 0.1 1.6e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Subtilase family RIO1 PF01163.17 EIM87875.1 - 2e-07 30.5 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EIM87875.1 - 2e-07 30.4 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM87875.1 - 9.4e-06 25.5 0.3 3.3e-05 23.7 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIM87875.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM87875.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polyketide_cyc PF03364.15 EIM87875.1 - 0.099 12.6 1.3 0.24 11.3 0.1 2.0 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport EcKinase PF02958.15 EIM87875.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 EIM87876.1 - 1.3e-06 27.8 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM87876.1 - 3.8e-06 26.3 0.0 7.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM87876.1 - 2e-05 24.4 0.3 7.8e-05 22.5 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIM87876.1 - 0.0053 15.8 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM87876.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIM87876.1 - 0.084 11.9 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Polyketide_cyc PF03364.15 EIM87876.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport TIP41 PF04176.8 EIM87878.1 - 1.4e-47 161.3 0.0 1.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.6 EIM87879.1 - 1.2e-31 109.9 11.9 1e-21 77.2 0.0 5.1 4 2 1 5 5 5 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 EIM87879.1 - 0.017 15.0 0.0 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EIM87879.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM87879.1 - 0.044 13.2 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIM87879.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EIM87879.1 - 0.11 11.8 0.0 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EIM87879.1 - 0.18 12.2 0.0 5.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Hep_59 PF07052.6 EIM87882.1 - 3.9e-27 94.6 3.8 3.9e-27 94.6 2.6 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 SurE PF01975.12 EIM87883.1 - 4.6e-36 123.9 0.0 6.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE p450 PF00067.17 EIM87884.1 - 2e-74 250.8 0.0 2.3e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_Tn3 PF01526.12 EIM87884.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain GMC_oxred_N PF00732.14 EIM87885.1 - 8.5e-58 195.8 0.0 1.1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87885.1 - 5.9e-34 117.4 0.1 9.6e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM87885.1 - 0.0001 21.3 0.2 0.00017 20.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EIM87885.1 - 0.00011 21.2 0.1 0.0056 15.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM87885.1 - 0.00038 20.4 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM87885.1 - 0.002 16.6 0.5 0.022 13.2 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EIM87885.1 - 0.0021 17.2 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIM87885.1 - 0.0024 16.7 0.1 0.0092 14.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM87885.1 - 0.035 13.9 0.3 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EIM87886.1 - 2.1e-51 174.8 0.0 2.9e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM87886.1 - 3.8e-33 114.8 0.0 6.4e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM87886.1 - 4.1e-05 23.5 0.4 0.00011 22.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM87886.1 - 0.00019 20.4 0.3 0.0043 15.9 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM87886.1 - 0.00092 18.2 0.3 0.0019 17.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM87886.1 - 0.0071 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIM87886.1 - 0.0093 14.4 0.1 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIM87886.1 - 0.026 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM87886.1 - 0.046 12.8 0.1 0.09 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.20 EIM87887.1 - 1.5e-11 44.5 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM87887.1 - 3.3e-07 30.3 0.0 4.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM87887.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 KR domain IncA PF04156.9 EIM87888.1 - 0.0067 16.0 0.4 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 IncA protein DUF4060 PF13269.1 EIM87888.1 - 0.12 12.2 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) DUF2303 PF10065.4 EIM87892.1 - 0.0069 15.2 0.0 0.054 12.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2303) SHR3_chaperone PF08229.6 EIM87893.1 - 0.3 10.0 0.1 15 4.5 0.0 2.8 2 0 0 2 2 2 0 ER membrane protein SH3 Pkinase PF00069.20 EIM87900.1 - 4e-07 29.4 0.0 1.3e-05 24.4 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87900.1 - 0.0015 17.6 0.0 0.01 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase MFS_1 PF07690.11 EIM87901.1 - 1.1e-17 63.7 54.7 3.9e-10 38.9 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM87901.1 - 0.0009 17.7 14.4 0.0009 17.7 10.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1146 PF06612.6 EIM87901.1 - 0.023 14.6 0.6 1.1 9.1 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) Btz PF09405.5 EIM87902.1 - 1.4e-08 34.7 0.8 1.4e-08 34.7 0.6 2.5 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DHQ_synthase PF01761.15 EIM87903.1 - 6.1e-55 185.9 0.0 7.4e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EIM87903.1 - 6.2e-12 45.3 0.0 9.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EIM87903.1 - 0.00071 18.3 0.0 0.0025 16.5 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase MFS_1 PF07690.11 EIM87904.1 - 4.3e-19 68.4 50.3 7.7e-11 41.2 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM87904.1 - 3.9e-07 28.8 6.8 3.9e-07 28.8 4.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein WD40 PF00400.27 EIM87905.1 - 2.5e-13 49.3 17.3 0.00029 20.5 0.0 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIM87905.1 - 2.7e-05 23.9 0.0 0.56 9.8 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIM87905.1 - 0.017 14.8 0.0 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LNS2 PF08235.8 EIM87908.1 - 1.4e-71 239.1 0.0 2.1e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EIM87908.1 - 2.1e-24 85.3 0.0 4.3e-22 77.8 0.0 2.5 1 1 0 1 1 1 1 lipin, N-terminal conserved region Arginase PF00491.16 EIM87909.1 - 5.9e-78 261.9 0.4 7.3e-78 261.6 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EIM87909.1 - 0.14 12.3 0.1 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Complex1_LYR_1 PF13232.1 EIM87910.1 - 5.9e-08 32.8 1.1 7.9e-08 32.4 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIM87910.1 - 4.6e-07 29.5 1.0 1.1e-06 28.3 0.7 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) JAB PF01398.16 EIM87911.1 - 5.3e-18 64.8 0.1 9e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIM87911.1 - 1.5e-09 37.9 0.0 3.2e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function A_amylase_inhib PF01356.14 EIM87911.1 - 0.055 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase inhibitor RLI PF04068.10 EIM87912.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI AFG1_ATPase PF03969.11 EIM87914.1 - 1.9e-93 313.1 0.0 4.1e-89 298.9 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EIM87914.1 - 1.1e-05 25.5 0.2 0.00015 21.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM87914.1 - 4.6e-05 23.5 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIM87914.1 - 0.00045 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIM87914.1 - 0.017 15.4 0.0 13 6.0 0.0 2.9 3 1 1 4 4 4 0 ABC transporter AAA_5 PF07728.9 EIM87914.1 - 0.019 14.6 0.0 0.05 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIM87914.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.13 EIM87914.1 - 0.092 12.3 0.1 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein ORC6 PF05460.8 EIM87914.1 - 0.1 11.6 2.8 0.072 12.1 0.3 1.8 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) ApoB100_C PF12491.3 EIM87914.1 - 0.17 11.5 0.6 0.66 9.6 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal UreF PF01730.11 EIM87916.1 - 7.5e-15 55.3 0.2 2.7e-14 53.5 0.1 1.8 1 1 0 1 1 1 1 UreF RRN3 PF05327.6 EIM87917.1 - 2.5e-153 511.2 0.0 2.6e-152 507.8 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3774 PF12609.3 EIM87917.1 - 0.027 15.3 2.2 0.027 15.3 1.5 2.1 2 0 0 2 2 2 0 Wound-induced protein Pkinase PF00069.20 EIM87919.1 - 1.3e-12 47.4 0.0 9.4e-11 41.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87919.1 - 0.00096 18.2 0.0 0.0071 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EIM87919.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 EIM87921.1 - 2.4e-11 43.2 0.0 3.4e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87921.1 - 0.00081 18.5 0.0 0.0021 17.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EIM87921.1 - 0.023 13.5 0.1 0.035 12.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DnaB PF00772.16 EIM87922.1 - 0.059 13.2 0.3 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain BASP1 PF05466.7 EIM87923.1 - 1.5 8.5 4.3 2.3 7.9 3.0 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Pkinase PF00069.20 EIM87924.1 - 6.7e-09 35.2 0.0 3.8e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87924.1 - 0.096 11.7 0.0 0.59 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase DUF1500 PF07389.7 EIM87924.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Ubiquitin_3 PF14836.1 EIM87925.1 - 0.0068 16.0 1.0 0.49 10.0 0.3 2.8 2 1 0 2 2 2 2 Ubiquitin-like domain Med2 PF11214.3 EIM87925.1 - 0.064 13.3 2.6 0.28 11.2 1.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 Nup54 PF13874.1 EIM87925.1 - 1.3 8.6 5.3 0.31 10.6 0.5 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4658 PF15555.1 EIM87926.1 - 0.026 14.3 3.4 0.063 13.1 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) Consortin_C PF15281.1 EIM87926.1 - 0.049 13.1 1.6 0.092 12.2 0.0 2.1 2 1 0 2 2 2 0 Consortin C-terminus Hepcidin PF06446.7 EIM87926.1 - 0.79 10.1 5.1 0.29 11.5 0.3 2.4 2 0 0 2 2 2 0 Hepcidin Pkinase PF00069.20 EIM87927.1 - 4.6e-08 32.5 0.0 1.4e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87927.1 - 0.0013 17.8 0.0 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase ApoLp-III PF07464.6 EIM87930.1 - 0.035 14.1 0.4 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Raftlin PF15250.1 EIM87931.1 - 4.7 5.6 6.1 0.29 9.6 0.8 1.5 2 0 0 2 2 2 0 Raftlin Pkinase PF00069.20 EIM87932.1 - 3.4e-09 36.2 0.0 3.6e-08 32.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87932.1 - 0.00011 21.4 0.0 0.00055 19.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EIM87932.1 - 0.0072 15.4 0.1 0.016 14.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIM87934.1 - 2.4e-16 59.7 0.0 7.1e-08 31.9 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87934.1 - 4.3e-09 35.8 0.0 0.0013 17.8 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EIM87934.1 - 0.0013 17.8 0.1 0.036 13.1 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIM87934.1 - 0.082 12.4 0.0 8 5.9 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EIM87934.1 - 0.12 11.1 0.1 4.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 FAD_binding_3 PF01494.14 EIM87935.1 - 4e-56 190.6 0.0 5.7e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM87935.1 - 4.1e-06 26.5 0.0 8.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Aldedh PF00171.17 EIM87936.1 - 1.1e-149 498.6 0.1 1.4e-149 498.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM87936.1 - 0.00029 19.6 0.0 0.00048 18.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Bin3 PF06859.7 EIM87937.1 - 2.5e-30 104.7 0.0 4e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 EIM87937.1 - 1.2e-15 58.0 0.0 1.8e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM87937.1 - 1.1e-13 51.2 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM87937.1 - 1.2e-09 37.9 0.0 9.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIM87937.1 - 2.5e-09 37.5 0.0 0.00053 20.4 0.0 2.4 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EIM87937.1 - 2.9e-06 27.3 0.0 6.7e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM87937.1 - 2e-05 24.9 0.0 0.21 12.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EIM87937.1 - 0.0002 21.6 0.0 0.00081 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM87937.1 - 0.00021 20.6 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIM87937.1 - 0.00036 19.6 0.0 0.00077 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EIM87937.1 - 0.0071 15.4 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EIM87937.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HAD_2 PF13419.1 EIM87938.1 - 3.1e-14 53.5 0.0 4.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM87938.1 - 1.3e-10 40.8 0.0 2.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM87938.1 - 2.6e-10 41.0 0.1 1.4e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM87938.1 - 0.04 14.0 0.0 0.053 13.6 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase F-box PF00646.28 EIM87940.1 - 4.6e-07 29.3 0.2 1.6e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM87940.1 - 2.7e-06 26.9 0.1 6.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-HC5HC2H_2 PF13832.1 EIM87941.1 - 0.007 16.3 0.3 0.0086 16.0 0.2 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C2HC PF01530.13 EIM87941.1 - 0.24 11.1 4.0 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2HC type Y_phosphatase3 PF13350.1 EIM87943.1 - 8.9e-43 146.3 0.0 1.9e-42 145.2 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EIM87943.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 EIM87943.1 - 0.00097 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIM87943.1 - 0.0052 16.1 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EIM87943.1 - 0.15 11.4 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Glyco_hydro_32N PF00251.15 EIM87944.1 - 3.4e-82 276.2 3.5 4.1e-82 275.9 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Epimerase PF01370.16 EIM87945.1 - 4.4e-17 62.3 0.5 2e-16 60.1 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM87945.1 - 8.5e-14 50.9 0.0 1.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM87945.1 - 3.7e-13 49.8 0.5 6.9e-13 48.9 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM87945.1 - 5.1e-08 32.1 0.2 4.7e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM87945.1 - 3.7e-06 26.3 1.2 5.3e-06 25.8 0.8 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIM87945.1 - 0.001 19.0 1.4 0.0027 17.6 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Glyco_tranf_2_3 PF13641.1 EIM87945.1 - 0.005 16.6 0.1 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Polysacc_synt_2 PF02719.10 EIM87945.1 - 0.026 13.4 0.5 0.036 12.9 0.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L1 PF00687.16 EIM87946.1 - 8e-50 169.2 2.8 9.7e-50 168.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Snf7 PF03357.16 EIM87947.1 - 1.5e-45 154.6 11.3 1.7e-45 154.4 7.8 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 EIM87947.1 - 0.00062 19.9 2.1 0.029 14.6 0.2 2.7 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1569 PF07606.6 EIM87947.1 - 0.022 14.6 0.7 0.037 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) FlaC_arch PF05377.6 EIM87947.1 - 0.03 14.2 4.7 7.3 6.5 0.9 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NuA4 PF09340.5 EIM87947.1 - 0.035 13.7 1.4 0.072 12.7 0.7 1.8 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Prefoldin_2 PF01920.15 EIM87947.1 - 0.039 13.7 12.4 2.3 8.0 0.0 3.4 2 1 1 3 3 3 0 Prefoldin subunit NgoMIV_restric PF09015.5 EIM87947.1 - 0.055 12.4 0.3 0.07 12.1 0.2 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme Mnd1 PF03962.10 EIM87947.1 - 0.37 10.4 11.3 1.6 8.3 7.8 1.9 1 1 0 1 1 1 0 Mnd1 family FlxA PF14282.1 EIM87947.1 - 0.42 10.5 9.3 0.4 10.6 3.8 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF342 PF03961.8 EIM87947.1 - 0.5 8.7 8.9 0.92 7.8 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) HeLo PF14479.1 EIM87947.1 - 1.9 8.1 8.1 3.9 7.1 0.4 2.1 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF4140 PF13600.1 EIM87947.1 - 2.7 8.4 5.9 12 6.3 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Syja_N PF02383.13 EIM87949.1 - 3.6e-78 262.5 0.0 4.8e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EIM87949.1 - 2.7e-25 89.7 0.2 4.4e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SseB_C PF14581.1 EIM87949.1 - 0.056 13.3 0.1 14 5.6 0.0 2.7 3 0 0 3 3 3 0 SseB protein C-terminal domain DEAD PF00270.24 EIM87950.1 - 3.5e-42 143.7 0.5 7.3e-42 142.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM87950.1 - 1.4e-28 98.5 0.1 3e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIM87950.1 - 0.012 15.3 0.2 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EIM87950.1 - 0.024 14.4 0.0 0.074 12.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM87950.1 - 0.05 13.7 0.3 0.21 11.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EIM87950.1 - 0.066 12.5 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EIM87950.1 - 0.11 11.9 0.2 0.31 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EIM87951.1 - 1.3e-18 66.4 1.5 1.6e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM87951.1 - 2.7e-15 56.0 0.0 5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM87951.1 - 3.1e-10 39.7 0.0 3.1e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM87951.1 - 0.023 14.5 0.4 0.078 12.8 0.3 1.8 1 1 0 1 1 1 0 RNA binding motif Usp PF00582.21 EIM87951.1 - 0.13 12.4 0.3 0.18 11.9 0.2 1.1 1 0 0 1 1 1 0 Universal stress protein family PBP PF01161.15 EIM87952.1 - 2.4e-18 66.3 0.1 3.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3846 PF12957.2 EIM87952.1 - 0.069 12.8 0.0 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) DUF928 PF06051.7 EIM87955.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Stanniocalcin PF03298.8 EIM87955.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Stanniocalcin family DUF761 PF05553.6 EIM87956.1 - 2.8 7.3 4.7 17 4.9 0.1 2.2 2 0 0 2 2 2 0 Cotton fibre expressed protein Abhydrolase_1 PF00561.15 EIM87957.1 - 1.8e-16 60.3 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM87957.1 - 1.1e-09 38.5 1.3 7.9e-09 35.7 0.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIM87957.1 - 0.05 13.0 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Zn_clus PF00172.13 EIM87958.1 - 5.8e-15 54.9 26.4 2.9e-07 30.2 7.2 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.16 EIM87959.1 - 1.4e-20 73.3 12.5 1.8e-20 73.0 8.6 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EIM87959.1 - 0.015 14.6 3.4 0.027 13.8 2.4 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway GrpE PF01025.14 EIM87959.1 - 0.53 9.8 5.8 0.83 9.1 3.8 1.5 1 1 0 1 1 1 0 GrpE Erv26 PF04148.8 EIM87960.1 - 1e-58 198.2 0.9 1.2e-58 197.9 0.6 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1440 PF07274.7 EIM87960.1 - 8.9 6.3 10.2 0.059 13.3 0.7 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) Pkinase PF00069.20 EIM87961.1 - 0.0012 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.13 EIM87962.1 - 1e-11 44.5 29.4 8e-06 25.6 8.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Hist_deacetyl PF00850.14 EIM87963.1 - 4.4e-77 259.4 0.0 7.8e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.14 EIM87964.1 - 5.8e-80 268.8 0.0 8.6e-80 268.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TFIIA PF03153.8 EIM87964.1 - 0.0046 16.9 14.5 0.0067 16.3 10.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cytochrome-c551 PF10643.4 EIM87964.1 - 0.068 12.4 0.3 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF1256 PF06866.6 EIM87964.1 - 0.18 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) Xan_ur_permease PF00860.15 EIM87965.1 - 6.4e-60 202.6 35.2 3.4e-58 196.9 24.4 2.1 1 1 0 1 1 1 1 Permease family F-box-like PF12937.2 EIM87966.1 - 9.7e-09 34.8 0.9 3.7e-08 32.9 0.6 2.1 1 0 0 1 1 1 1 F-box-like SBDS PF01172.13 EIM87967.1 - 3e-16 58.9 0.1 3.2e-16 58.8 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AvrRpt-cleavage PF05627.6 EIM87967.1 - 0.0085 15.1 0.1 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Cleavage site for pathogenic type III effector avirulence factor Avr HATPase_c_3 PF13589.1 EIM87968.1 - 1.8e-10 40.5 0.0 3.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EIM87968.1 - 3.6e-08 32.8 0.0 1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EIM87968.1 - 5.5e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EIM87968.1 - 0.00032 20.3 0.5 0.0084 15.7 0.0 3.2 4 0 0 4 4 4 1 MutL C terminal dimerisation domain Nucleoporin_FG PF13634.1 EIM87969.1 - 7.2e-05 22.9 216.4 0.0038 17.4 21.3 6.8 2 1 1 3 3 3 1 Nucleoporin FG repeat region zf-CCCH PF00642.19 EIM87969.1 - 0.0022 17.6 1.2 0.0036 16.9 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RAB3GAP2_N PF14655.1 EIM87969.1 - 1.1 8.1 6.0 0.48 9.3 2.4 1.6 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase PF00069.20 EIM87970.1 - 2e-60 204.1 0.0 2.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM87970.1 - 1.5e-30 106.1 0.0 2.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM87970.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM87970.1 - 0.09 12.4 0.3 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyoxal_oxid_N PF07250.6 EIM87971.1 - 4.4e-58 196.2 0.0 1.2e-57 194.7 0.0 1.8 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM87971.1 - 7.2e-18 64.5 0.7 1.4e-17 63.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM87971.1 - 9.4e-06 25.3 0.2 0.61 9.9 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 EIM87972.1 - 2.8e-55 187.0 0.0 5.8e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM87972.1 - 1.3e-17 63.6 0.1 3.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM87972.1 - 1.4e-06 27.9 0.2 0.61 9.8 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain IU_nuc_hydro PF01156.14 EIM87973.1 - 7.2e-91 304.6 0.0 8.3e-91 304.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.18 EIM87974.1 - 4.1e-79 266.1 0.0 9.8e-78 261.6 0.0 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIM87974.1 - 5.7e-26 91.0 2.1 1.3e-20 73.5 0.0 3.1 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIM87974.1 - 7.9e-17 61.3 0.0 7.3e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF3499 PF12005.3 EIM87974.1 - 0.045 13.9 0.4 0.65 10.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) YgaB PF14182.1 EIM87974.1 - 6 7.1 13.6 0.11 12.8 1.1 3.1 3 0 0 3 3 3 0 YgaB-like protein TMF_TATA_bd PF12325.3 EIM87974.1 - 7.9 6.2 19.7 0.19 11.4 0.1 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Cyto_ox_2 PF02322.10 EIM87975.1 - 0.072 12.2 11.3 0.04 13.0 5.9 1.8 1 1 1 2 2 2 0 Cytochrome oxidase subunit II adh_short PF00106.20 EIM87976.1 - 1.7e-16 60.6 1.8 1.9e-16 60.4 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM87976.1 - 2.8e-05 23.8 0.2 9.9e-05 22.0 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EIM87976.1 - 0.00024 20.6 0.1 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM87976.1 - 0.00068 19.6 0.2 0.0031 17.5 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding MCM PF00493.18 EIM87977.1 - 3.5e-137 456.6 0.9 5.1e-137 456.1 0.1 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIM87977.1 - 3.5e-22 79.1 0.1 1.1e-21 77.5 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIM87977.1 - 4.5e-07 29.2 0.0 4e-06 26.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIM87977.1 - 0.0025 17.4 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIM87977.1 - 0.0033 16.9 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIM87977.1 - 0.032 13.9 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tom7 PF08038.7 EIM87978.1 - 1.6e-12 46.6 0.1 2.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 TOM7 family zf-C3HC4_2 PF13923.1 EIM87979.1 - 7.2e-09 35.5 16.1 7.2e-09 35.5 11.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM87979.1 - 8.7e-06 25.3 20.0 5.8e-05 22.6 8.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM87979.1 - 1.7e-05 24.5 23.7 6.1e-05 22.7 10.9 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EIM87979.1 - 0.00016 21.2 13.8 0.00016 21.2 9.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM87979.1 - 0.00025 20.7 18.7 0.0008 19.0 8.8 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 EIM87979.1 - 0.14 12.0 17.0 0.038 13.7 6.4 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EIM87979.1 - 1.7 8.6 19.6 0.46 10.3 7.7 3.5 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Glyco_hydro_3 PF00933.16 EIM87980.1 - 3.8e-85 285.4 0.0 5.2e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM87980.1 - 2.2e-59 200.7 0.0 7.6e-59 198.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM87980.1 - 1.5e-18 66.4 0.1 2.3e-17 62.7 0.0 2.7 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EIM87980.1 - 1.5e-06 27.9 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF600 PF04634.7 EIM87981.1 - 0.0083 16.1 1.4 0.74 9.8 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function, DUF600 Helicase_C PF00271.26 EIM87982.1 - 7.3e-17 61.0 0.0 1.7e-15 56.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM87982.1 - 4.9e-15 55.4 0.0 1.3e-13 50.7 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 EIM87982.1 - 1.9e-06 27.5 0.1 4.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain F-box-like PF12937.2 EIM87983.1 - 3.6e-09 36.1 0.1 8.5e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Fe-ADH PF00465.14 EIM87984.1 - 1.4e-61 208.1 0.0 1.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIM87984.1 - 6e-07 29.0 0.3 0.00075 18.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EIM87984.1 - 0.028 13.3 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 3-dehydroquinate synthase Vac14_Fig4_bd PF11916.3 EIM87985.1 - 1e-80 269.2 6.3 1.6e-80 268.5 4.3 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EIM87985.1 - 7.4e-42 141.6 0.0 7.9e-38 128.7 0.0 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EIM87985.1 - 4e-16 57.5 3.0 4.1e-05 23.3 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EIM87985.1 - 4.2e-10 39.7 0.2 0.32 11.3 0.0 5.2 4 2 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EIM87985.1 - 5.1e-07 29.9 0.2 0.47 11.0 0.0 5.9 6 0 0 6 6 6 2 HEAT-like repeat ParcG PF10274.4 EIM87985.1 - 0.00051 19.9 0.4 0.35 10.7 0.0 3.3 3 0 0 3 3 3 1 Parkin co-regulated protein Cnd1 PF12717.2 EIM87985.1 - 0.00092 19.1 1.6 1.2 8.9 0.0 3.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4106 PF13388.1 EIM87985.1 - 4.1 6.2 10.4 6.5 5.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RR_TM4-6 PF06459.7 EIM87985.1 - 8.4 6.1 7.1 0.54 10.1 0.9 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HPP PF04982.8 EIM87986.1 - 1.8e-40 137.4 6.4 1.8e-40 137.4 4.4 1.6 2 0 0 2 2 2 1 HPP family Tmemb_14 PF03647.8 EIM87986.1 - 0.0013 19.0 7.9 0.0042 17.4 0.2 2.5 1 1 2 3 3 3 2 Transmembrane proteins 14C DUF4231 PF14015.1 EIM87986.1 - 2.7 8.0 9.3 0.92 9.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Fe-ADH PF00465.14 EIM87987.1 - 7.2e-64 215.7 0.0 9.1e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIM87987.1 - 3.8e-08 32.9 0.0 0.00084 18.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EIM87987.1 - 0.01 14.7 0.0 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 3-dehydroquinate synthase Clathrin PF00637.15 EIM87988.1 - 9.4e-23 80.3 0.0 2.2e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EIM87988.1 - 0.00072 19.3 6.1 0.006 16.3 4.2 2.4 1 1 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.4 EIM87988.1 - 0.0017 18.4 1.8 0.025 14.7 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EIM87988.1 - 0.011 15.4 2.7 0.062 13.0 1.9 2.2 1 1 0 1 1 1 0 zinc-RING finger domain TPR_12 PF13424.1 EIM87988.1 - 0.022 14.6 0.1 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EIM87988.1 - 0.79 9.4 6.2 11 5.7 1.7 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Daxx PF03344.10 EIM87988.1 - 1.1 7.6 19.9 1.8 6.9 13.8 1.2 1 0 0 1 1 1 0 Daxx Family zf-C3HC4_2 PF13923.1 EIM87988.1 - 2.2 8.4 5.6 4.3 7.4 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YqfQ PF14181.1 EIM87988.1 - 2.2 8.2 4.1 4.2 7.3 2.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein SAPS PF04499.10 EIM87988.1 - 5 5.6 5.3 7.6 5.0 3.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_hydro_3_C PF01915.17 EIM87989.1 - 1.7e-74 250.1 0.0 2.6e-73 246.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EIM87989.1 - 7.4e-74 248.4 0.0 1e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EIM87989.1 - 3.9e-23 81.1 0.1 7.8e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIM87989.1 - 8.7e-09 35.1 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FAIM1 PF06905.8 EIM87989.1 - 0.046 12.8 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) DUF3575 PF12099.3 EIM87989.1 - 0.073 12.1 0.4 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) BRCT PF00533.21 EIM87990.1 - 3.7e-08 33.3 0.0 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EIM87990.1 - 5.6e-05 23.2 0.1 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.2 EIM87990.1 - 0.0001 22.0 0.0 0.00063 19.5 0.0 2.3 1 1 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 EIM87990.1 - 0.0032 17.1 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) TFIIA PF03153.8 EIM87990.1 - 0.44 10.4 8.2 0.82 9.4 5.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF869 PF05911.6 EIM87992.1 - 0.001 17.4 8.2 0.0016 16.8 5.7 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EIM87992.1 - 0.0016 18.1 11.9 0.023 14.4 2.8 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIM87992.1 - 0.0028 16.7 13.8 0.0053 15.8 9.6 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 EIM87992.1 - 0.011 15.3 15.9 0.019 14.5 11.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF812 PF05667.6 EIM87992.1 - 0.024 13.1 10.0 0.053 12.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EIM87992.1 - 0.03 14.6 9.0 1.2 9.4 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EzrA PF06160.7 EIM87992.1 - 0.055 11.6 8.4 0.082 11.0 5.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EIM87992.1 - 0.1 11.7 3.7 0.16 11.0 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Peptidase_S46 PF10459.4 EIM87992.1 - 0.91 7.8 10.2 1.4 7.2 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 EIM87992.1 - 1.4 8.4 25.7 78 2.7 17.8 2.4 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 EIM87992.1 - 2 8.4 9.2 12 5.9 0.1 2.8 1 1 1 2 2 2 0 DivIVA protein TBPIP PF07106.8 EIM87992.1 - 2.1 7.8 10.1 4.4 6.8 1.0 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EIM87992.1 - 2.7 8.1 7.2 5.9 7.0 5.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PspB PF06667.7 EIM87992.1 - 6.1 6.8 5.7 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Mnd1 PF03962.10 EIM87992.1 - 6.7 6.3 15.2 1.5 8.4 6.9 2.1 1 1 1 2 2 2 0 Mnd1 family zf-CCHC PF00098.18 EIM87994.1 - 2.3e-07 30.3 3.8 4.6e-07 29.4 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIM87994.1 - 0.00044 20.2 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIM87994.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.1 EIM87994.1 - 0.05 13.3 0.3 0.19 11.4 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIM87994.1 - 0.058 13.0 0.3 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM87994.1 - 0.059 12.8 2.7 0.13 11.7 1.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peptidase_A2B PF12384.3 EIM87994.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase ADH_N_assoc PF13823.1 EIM87994.1 - 0.17 11.5 0.8 0.5 10.0 0.5 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Tim17 PF02466.14 EIM87997.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.4 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF3493 PF11998.3 EIM87997.1 - 7.3 6.5 8.0 9.7 6.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) Ribosomal_L7Ae PF01248.21 EIM87998.1 - 1.5e-26 91.7 1.4 1.8e-26 91.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 EIM87999.1 - 2.7e-29 99.9 22.8 1.4e-10 40.6 1.0 6.9 6 1 1 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EIM87999.1 - 0.0005 18.3 6.2 0.054 11.6 2.9 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIM87999.1 - 0.00093 18.3 0.1 0.82 8.7 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EIM87999.1 - 0.0035 15.2 0.0 0.0059 14.4 0.0 1.3 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 EIM87999.1 - 0.042 13.5 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIM87999.1 - 0.048 12.4 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region DUF3312 PF11768.3 EIM87999.1 - 0.091 10.9 0.0 0.19 9.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) PD40 PF07676.7 EIM87999.1 - 0.18 11.5 6.4 1e+02 2.7 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIM87999.1 - 0.54 8.9 3.9 4.7 5.8 0.1 2.5 1 1 0 2 2 2 0 Nup133 N terminal like F-box-like PF12937.2 EIM88001.1 - 3e-08 33.2 0.2 9.6e-08 31.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like 2OG-FeII_Oxy_2 PF13532.1 EIM88002.1 - 8.3e-14 51.8 0.0 1.4e-13 51.1 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM88002.1 - 3.3e-05 24.0 0.0 0.00053 20.2 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ubiquitin PF00240.18 EIM88003.1 - 6.8e-25 86.2 0.0 7.5e-25 86.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM88003.1 - 8.4e-15 54.2 0.2 9.2e-15 54.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM88003.1 - 0.00074 19.7 0.0 0.00087 19.4 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin-like domain 4HBT PF03061.17 EIM88004.1 - 2e-09 37.4 0.2 4.9e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily RelB PF04221.7 EIM88004.1 - 0.043 13.5 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 RelB antitoxin 4HBT_3 PF13622.1 EIM88004.1 - 0.091 12.4 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Borrelia_P83 PF05262.6 EIM88005.1 - 0.006 14.9 31.6 0.0077 14.5 21.9 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein Ham1p_like PF01725.11 EIM88007.1 - 1.5e-55 187.4 0.0 1.7e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Pap_E4 PF02711.9 EIM88008.1 - 0.063 14.1 2.3 0.17 12.7 1.6 1.7 1 0 0 1 1 1 0 E4 protein ATG22 PF11700.3 EIM88009.1 - 5.3e-102 341.7 21.8 6e-102 341.5 15.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIM88009.1 - 3.5e-15 55.5 31.4 1.1e-09 37.5 5.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 EIM88009.1 - 0.086 12.3 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Short C-terminal domain Fungal_trans PF04082.13 EIM88010.1 - 0.021 13.6 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain F-box-like PF12937.2 EIM88011.1 - 2.3e-07 30.4 0.2 4.3e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88011.1 - 0.023 14.3 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain Voldacs PF03517.8 EIM88011.1 - 0.046 13.5 0.2 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Troponin-I_N PF11636.3 EIM88011.1 - 0.11 12.1 0.1 0.33 10.6 0.1 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 Cytochrom_c3_2 PF14537.1 EIM88012.1 - 0.51 10.7 4.2 0.46 10.8 0.5 2.4 2 0 0 2 2 2 0 Cytochrome c3 CHAT PF12770.2 EIM88013.1 - 8.7e-33 113.6 0.1 1.8e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM88013.1 - 1.1e-25 89.3 31.6 0.014 15.3 0.1 14.0 5 3 8 14 14 14 10 Tetratricopeptide repeat TPR_11 PF13414.1 EIM88013.1 - 1.5e-20 72.5 28.5 0.0046 16.5 0.3 12.1 7 3 7 14 14 14 8 TPR repeat TPR_17 PF13431.1 EIM88013.1 - 1e-05 25.3 3.8 14 6.1 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Sel1 PF08238.7 EIM88013.1 - 0.00069 20.1 2.0 7.2 7.3 0.0 6.4 8 0 0 8 8 8 1 Sel1 repeat TPR_2 PF07719.12 EIM88013.1 - 0.019 14.8 28.4 92 3.3 0.0 13.8 16 0 0 16 16 16 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIM88013.1 - 0.033 13.9 13.7 14 5.7 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM88013.1 - 1.4 8.8 20.5 25 4.9 0.3 9.1 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM88013.1 - 1.6 9.3 7.3 80 4.0 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Serglycin PF04360.7 EIM88014.1 - 0.049 13.3 2.2 0.61 9.7 1.6 2.4 2 0 0 2 2 2 0 Serglycin BTB PF00651.26 EIM88016.1 - 0.00055 19.9 0.0 0.00096 19.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pro_isomerase PF00160.16 EIM88017.1 - 4.7e-37 127.5 0.0 7e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EIM88017.1 - 4.2e-16 58.3 0.0 7.3e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88017.1 - 5.1e-12 45.5 0.1 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88017.1 - 9.1e-08 31.8 0.1 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EIM88017.1 - 4.9 5.5 6.5 10 4.4 4.5 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 EIM88018.1 - 2.9e-39 131.5 11.9 9.9e-08 31.5 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 EIM88018.1 - 2.2 8.6 6.3 15 6.0 0.0 4.0 4 1 0 4 4 4 0 PQQ-like domain PHD PF00628.24 EIM88019.1 - 3.7e-08 32.9 14.2 7.9e-08 31.8 3.6 2.6 2 1 0 2 2 2 2 PHD-finger Elf1 PF05129.8 EIM88019.1 - 0.14 11.8 7.5 1.4 8.6 0.3 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 EIM88019.1 - 0.21 11.1 3.6 1.2 8.7 2.5 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-HC5HC2H_2 PF13832.1 EIM88019.1 - 0.28 11.1 5.5 0.29 11.1 0.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-MIZ PF02891.15 EIM88019.1 - 0.67 9.5 7.6 0.15 11.6 1.8 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zinc_ribbon_4 PF13717.1 EIM88019.1 - 0.72 9.5 3.9 5.1 6.8 2.7 2.5 1 1 0 1 1 1 0 zinc-ribbon domain Tocopherol_cycl PF14249.1 EIM88020.1 - 0.0096 14.6 0.0 0.029 13.0 0.0 1.7 2 0 0 2 2 2 1 Tocopherol cyclase Aldedh PF00171.17 EIM88023.1 - 1e-107 360.3 0.0 1.2e-107 360.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Myb_DNA-binding PF00249.26 EIM88024.1 - 7.8e-16 57.8 11.0 4.9e-10 39.3 0.1 4.3 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM88024.1 - 6e-14 51.9 9.7 2.4e-09 37.1 0.3 3.8 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIM88024.1 - 0.0001 22.3 1.0 0.0001 22.3 0.7 4.1 3 2 2 5 5 5 1 Myb/SANT-like DNA-binding domain Herpes_U47 PF05467.6 EIM88024.1 - 0.15 9.8 0.0 0.2 9.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 MADF_DNA_bdg PF10545.4 EIM88024.1 - 1.5 9.0 8.4 35 4.6 0.7 3.9 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like F-box-like PF12937.2 EIM88025.1 - 2.1e-09 36.9 0.2 5.1e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like Sec15 PF04091.7 EIM88026.1 - 2.8e-74 250.2 1.3 2.8e-74 250.2 0.9 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.6 EIM88026.1 - 2.3e-07 30.5 0.3 1.1e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 EIM88026.1 - 0.00032 20.4 0.1 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.4 EIM88026.1 - 0.00042 20.2 0.2 0.00042 20.2 0.2 3.3 4 0 0 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.6 EIM88026.1 - 0.0036 17.1 5.0 0.0056 16.5 0.3 3.2 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 EIM88026.1 - 0.043 13.4 7.0 0.047 13.3 0.3 3.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF479 PF04336.7 EIM88026.1 - 0.045 13.8 5.4 0.92 9.6 0.1 4.4 4 1 1 5 5 5 0 Protein of unknown function, DUF479 CENP-F_leu_zip PF10473.4 EIM88026.1 - 0.14 11.9 3.1 0.17 11.7 0.0 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dynamin_M PF01031.15 EIM88026.1 - 0.17 10.6 3.8 2.6 6.7 0.1 3.2 4 0 0 4 4 4 0 Dynamin central region NPV_P10 PF05531.7 EIM88026.1 - 0.43 10.8 4.2 1.7 8.9 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Arf PF00025.16 EIM88027.1 - 5e-79 263.5 0.1 5.7e-79 263.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM88027.1 - 1.1e-14 54.0 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIM88027.1 - 5.9e-13 48.5 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EIM88027.1 - 2.7e-12 46.0 1.2 3.5e-09 35.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIM88027.1 - 3.3e-11 42.7 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM88027.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIM88027.1 - 5.1e-06 26.4 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM88027.1 - 0.0065 15.9 0.1 0.056 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EIM88027.1 - 0.0067 15.5 0.4 0.014 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EIM88027.1 - 0.033 14.0 0.2 0.14 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIM88027.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Claudin_2 PF13903.1 EIM88028.1 - 0.011 15.3 0.3 3.2 7.4 0.6 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Lactamase_B_2 PF12706.2 EIM88029.1 - 1.8e-31 109.2 0.0 2.6e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIM88029.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM88029.1 - 0.00013 21.6 0.2 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Nup188 PF10487.4 EIM88030.1 - 1.3e-09 36.6 1.7 2.5e-07 29.0 0.0 3.1 3 1 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 EIM88030.1 - 0.00018 18.6 0.2 0.0044 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3414) OppC_N PF12911.2 EIM88031.1 - 0.089 12.1 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Utp14 PF04615.8 EIM88031.1 - 2.8 5.9 13.4 4.1 5.4 9.3 1.1 1 0 0 1 1 1 0 Utp14 protein Adap_comp_sub PF00928.16 EIM88032.1 - 7.7e-25 87.4 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIM88032.1 - 3.7e-07 29.9 0.1 5.5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4164 PF13747.1 EIM88034.1 - 0.0014 18.7 9.6 0.0028 17.7 6.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) DUF2046 PF09755.4 EIM88034.1 - 0.011 14.7 0.9 0.018 13.9 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cep57_CLD_2 PF14197.1 EIM88034.1 - 0.038 13.9 7.3 0.16 11.9 1.4 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 EIM88034.1 - 0.049 13.3 1.8 0.12 12.1 0.5 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EIM88034.1 - 0.15 12.0 1.4 3 7.8 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor Spindle_Spc25 PF08234.7 EIM88034.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 Swi5 PF07061.6 EIM88035.1 - 2.4e-19 68.8 2.0 2.8e-19 68.6 1.4 1.0 1 0 0 1 1 1 1 Swi5 Lzipper-MIP1 PF14389.1 EIM88035.1 - 0.0037 17.3 3.1 0.0045 17.0 2.2 1.4 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Med21 PF11221.3 EIM88035.1 - 0.013 15.4 1.8 0.019 14.9 1.2 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Macoilin PF09726.4 EIM88035.1 - 0.037 12.3 2.2 0.042 12.1 1.5 1.0 1 0 0 1 1 1 0 Transmembrane protein HOOK PF05622.7 EIM88035.1 - 0.053 11.3 3.3 0.062 11.1 2.3 1.0 1 0 0 1 1 1 0 HOOK protein DUF4461 PF14688.1 EIM88035.1 - 0.075 12.3 0.5 0.074 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) IncA PF04156.9 EIM88035.1 - 0.098 12.2 2.1 0.12 12.0 1.4 1.1 1 0 0 1 1 1 0 IncA protein Herpes_UL36 PF03586.8 EIM88035.1 - 0.099 11.7 1.3 0.1 11.7 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DUF4140 PF13600.1 EIM88035.1 - 0.11 12.9 0.9 0.19 12.1 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3391 PF11871.3 EIM88035.1 - 0.12 12.5 0.9 0.14 12.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1415 PF07209.7 EIM88035.1 - 0.12 12.0 0.5 0.12 12.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Mnd1 PF03962.10 EIM88035.1 - 0.22 11.1 2.0 0.27 10.8 1.4 1.0 1 0 0 1 1 1 0 Mnd1 family Occludin_ELL PF07303.8 EIM88035.1 - 0.23 12.2 1.6 0.27 12.0 1.1 1.1 1 0 0 1 1 1 0 Occludin homology domain DivIC PF04977.10 EIM88035.1 - 0.41 10.1 2.8 0.51 9.8 2.0 1.4 1 1 0 1 1 1 0 Septum formation initiator WD40_alt PF14077.1 EIM88035.1 - 0.79 9.4 2.7 0.94 9.1 0.6 2.0 1 1 1 2 2 2 0 Alternative WD40 repeat motif RCC1 PF00415.13 EIM88036.1 - 4.7e-26 90.7 24.1 5.8e-08 32.8 2.1 8.2 7 2 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM88036.1 - 8.5e-11 41.1 29.6 7.8e-05 22.1 0.2 6.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat OPT PF03169.10 EIM88038.1 - 1.8e-139 466.0 49.3 2.1e-139 465.8 34.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PdxA PF04166.7 EIM88041.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA RNA_pol_Rpb1_5 PF04998.12 EIM88042.1 - 6.1e-83 278.2 0.0 1e-82 277.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIM88042.1 - 1.3e-61 207.4 0.1 2.3e-61 206.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIM88042.1 - 1e-37 129.2 0.0 2.2e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EIM88042.1 - 1.3e-31 110.1 0.2 8.2e-24 84.4 0.0 2.9 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EIM88042.1 - 2.1e-21 75.6 0.0 6.9e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 AA_permease PF00324.16 EIM88043.1 - 2.1e-105 352.8 42.6 2.6e-105 352.5 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM88043.1 - 7.8e-34 116.9 43.1 1.1e-33 116.4 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_9 PF13527.1 EIM88044.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EIM88045.1 - 3.1e-42 144.5 0.0 4.9e-25 88.1 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88045.1 - 1.7e-12 47.0 0.0 1.7e-09 37.1 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIM88045.1 - 0.00011 22.0 0.2 0.00026 20.8 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDC45 PF02724.9 EIM88045.1 - 0.11 10.5 6.7 0.2 9.6 4.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Pneumo_att_G PF05539.6 EIM88045.1 - 2.6 7.3 10.1 4.7 6.4 7.0 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NUDIX PF00293.23 EIM88046.1 - 6.5e-14 51.7 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.4 EIM88047.1 - 0.025 14.0 5.4 0.028 13.8 3.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3629 PF12302.3 EIM88047.1 - 0.041 13.2 0.2 0.048 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Upf2 PF04050.9 EIM88047.1 - 0.079 12.7 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Chitin_synth_2 PF03142.10 EIM88048.1 - 6e-239 793.8 0.2 7.8e-239 793.4 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIM88048.1 - 8.8e-120 400.8 0.0 1.5e-119 400.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIM88048.1 - 5.7e-19 67.6 0.0 7.2e-13 48.1 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EIM88048.1 - 1e-17 64.6 0.0 1.8e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIM88048.1 - 7.5e-16 58.4 7.4 7.5e-16 58.4 5.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EIM88048.1 - 1.1e-13 50.6 0.3 7.5e-13 48.0 0.2 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EIM88048.1 - 5.6e-08 32.6 0.0 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIM88048.1 - 5e-05 22.6 0.0 0.00064 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF4592 PF15262.1 EIM88048.1 - 0.027 15.0 0.2 0.027 15.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Coatomer_WDAD PF04053.9 EIM88049.1 - 5.5e-149 496.7 0.0 1.1e-148 495.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EIM88049.1 - 5.8e-50 165.4 6.8 1.3e-09 37.5 0.1 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIM88049.1 - 2.2e-05 24.1 0.1 5.6 6.7 0.0 4.7 4 1 1 5 5 5 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EIM88049.1 - 0.037 12.1 1.0 8.8 4.3 0.1 3.5 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Abi PF02517.11 EIM88052.1 - 5e-12 45.7 6.3 5e-12 45.7 4.4 2.8 3 1 0 3 3 3 1 CAAX protease self-immunity Band_7 PF01145.20 EIM88053.1 - 3.5e-23 82.4 3.7 6.1e-23 81.6 2.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TroA PF01297.12 EIM88053.1 - 0.092 11.9 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Periplasmic solute binding protein family Acetyltransf_7 PF13508.1 EIM88054.1 - 3.9e-10 39.7 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM88054.1 - 1.2e-07 31.8 0.0 4.5e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM88054.1 - 1.5e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM88054.1 - 3.6e-05 23.6 0.0 9.4e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM88054.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EIM88054.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HEAT_EZ PF13513.1 EIM88054.1 - 0.1 13.0 0.1 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 HEAT-like repeat Acetyltransf_8 PF13523.1 EIM88054.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4243 PF14027.1 EIM88055.1 - 6.5e-72 242.7 0.0 7.7e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pkinase PF00069.20 EIM88057.1 - 3.2e-52 177.2 0.0 4.2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88057.1 - 1.5e-26 93.0 0.0 1.9e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM88057.1 - 0.0031 17.2 0.0 0.05 13.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM88057.1 - 0.012 14.6 0.0 0.031 13.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIM88057.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Iso_dh PF00180.15 EIM88058.1 - 6.1e-79 265.4 0.0 7.7e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 EIM88059.1 - 0.00019 21.4 0.1 0.00019 21.4 0.1 2.2 2 1 0 3 3 3 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 EIM88060.1 - 8.6e-13 48.1 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM88060.1 - 4.4e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM88060.1 - 5.4e-05 22.8 0.0 9.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIM88060.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM88060.1 - 0.0097 15.7 0.1 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2052 PF09747.4 EIM88061.1 - 1.7e-05 24.8 4.1 2.6e-05 24.2 2.8 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Lipase_GDSL_2 PF13472.1 EIM88062.1 - 1.2e-08 35.3 1.0 1.5e-08 34.9 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM88062.1 - 0.0056 16.5 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LSM PF01423.17 EIM88063.1 - 2.7e-19 68.4 0.0 3.3e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2034 PF10356.4 EIM88063.1 - 0.031 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Chitin_synth_1 PF01644.12 EIM88064.1 - 2.7e-64 215.8 0.1 4.5e-64 215.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIM88064.1 - 4.4e-25 87.1 0.1 8.8e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIM88064.1 - 1.2e-24 86.6 0.0 1.2e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM88064.1 - 1.1e-09 38.2 9.9 2.6e-08 33.8 6.9 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM88064.1 - 1.2e-07 31.8 0.0 4.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-C3HC4 PF00097.20 EIM88065.1 - 1.1e-07 31.4 0.6 3e-07 29.9 0.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM88065.1 - 1.6e-07 31.0 7.9 2.5e-06 27.2 5.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM88065.1 - 2.5e-07 30.5 2.1 1.4e-05 25.0 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM88065.1 - 2.4e-05 24.3 0.4 3.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIM88065.1 - 4e-05 23.1 0.5 0.0028 17.2 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM88065.1 - 0.00017 21.2 3.4 0.0017 18.0 2.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EIM88065.1 - 0.0015 18.0 3.9 0.009 15.5 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-met2 PF12907.2 EIM88065.1 - 0.0022 17.9 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding zf-Nse PF11789.3 EIM88065.1 - 0.014 14.9 0.3 0.04 13.4 0.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EIM88065.1 - 0.018 14.6 0.2 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2HC5 PF06221.8 EIM88065.1 - 0.023 14.4 0.1 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-Apc11 PF12861.2 EIM88065.1 - 0.035 13.9 0.4 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EIM88065.1 - 0.068 13.0 5.0 0.22 11.4 0.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 EIM88065.1 - 0.079 12.9 2.4 11 6.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger Baculo_IE-1 PF05290.6 EIM88065.1 - 0.084 12.6 0.3 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 EIM88065.1 - 0.097 12.1 0.1 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EIM88065.1 - 0.11 12.2 5.8 0.075 12.7 1.0 2.6 2 1 1 3 3 3 0 RING-type zinc-finger Spo12 PF05032.7 EIM88066.1 - 2.2e-09 36.7 0.5 4.2e-09 35.8 0.3 1.5 1 0 0 1 1 1 1 Spo12 family DUF3245 PF11595.3 EIM88066.1 - 0.018 15.2 1.3 0.025 14.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Nucleoplasmin PF03066.10 EIM88066.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Bd3614_N PF14442.1 EIM88066.1 - 0.23 11.4 2.4 0.32 10.9 1.7 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Sigma70_ner PF04546.8 EIM88066.1 - 0.89 9.1 3.5 1.1 8.8 2.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Ras PF00071.17 EIM88068.1 - 6.7e-45 152.3 0.4 7.7e-45 152.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM88068.1 - 4.4e-16 59.4 0.2 6.4e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM88068.1 - 9.1e-06 25.0 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIM88068.1 - 3.4e-05 23.7 0.0 4.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIM88068.1 - 0.00029 20.0 0.1 0.00034 19.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIM88068.1 - 0.0013 18.1 0.4 0.0078 15.6 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EIM88068.1 - 0.0044 16.7 0.2 0.006 16.3 0.1 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EIM88068.1 - 0.0074 16.1 0.0 0.0089 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EIM88068.1 - 0.021 14.1 0.1 0.32 10.2 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Baculo_LEF-10 PF07206.6 EIM88068.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) Glyco_hydro_2 PF00703.16 EIM88069.1 - 4.8e-09 36.6 0.1 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EIM88069.1 - 1.6e-05 24.5 0.1 4.8e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EIM88069.1 - 0.00017 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Piwi PF02171.12 EIM88070.1 - 4.3e-85 285.3 0.0 6.4e-85 284.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIM88070.1 - 1.8e-17 62.4 0.0 3.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIM88070.1 - 6.6e-10 38.4 0.0 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Histidinol_dh PF00815.15 EIM88071.1 - 3e-172 572.9 1.4 4.3e-172 572.3 1.0 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EIM88071.1 - 9.7e-26 89.2 0.2 1.8e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EIM88071.1 - 2e-08 34.3 0.2 4.5e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Transket_pyr PF02779.19 EIM88072.1 - 2.6e-47 160.5 0.0 4.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIM88072.1 - 1.8e-42 144.1 0.1 3.8e-42 143.1 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain adh_short PF00106.20 EIM88073.1 - 2.5e-30 105.5 0.5 3.9e-30 104.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM88073.1 - 5.4e-14 52.2 0.5 1.4e-13 50.9 0.3 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM88073.1 - 1.5e-12 47.7 0.0 1.9e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM88073.1 - 0.00026 20.4 0.0 0.00068 19.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM88073.1 - 0.00039 20.4 0.3 0.0015 18.5 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIM88073.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 EIM88073.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF1776 PF08643.5 EIM88073.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidohydro_2 PF04909.9 EIM88074.1 - 7.8e-14 51.8 0.0 2e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIM88074.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase DUF3140 PF11338.3 EIM88075.1 - 1.2e-20 73.3 0.5 1.2e-20 73.3 0.4 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF3140) Raptor_N PF14538.1 EIM88076.1 - 1.2e-62 210.2 0.0 2.3e-62 209.3 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EIM88076.1 - 3.4e-13 48.9 14.3 3.4e-07 29.8 0.7 6.8 6 1 1 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 EIM88076.1 - 1.3e-05 24.8 0.1 0.00016 21.4 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EIM88076.1 - 0.003 17.9 1.5 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 EIM88076.1 - 0.0051 17.0 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats Peptidase_C14 PF00656.17 EIM88076.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain CPSF100_C PF13299.1 EIM88077.1 - 2.9e-27 95.8 0.0 2.9e-27 95.8 0.0 2.8 4 0 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EIM88077.1 - 2.5e-20 72.6 0.0 7.6e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EIM88077.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EIM88077.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Raptor_N PF14538.1 EIM88078.1 - 1.1e-44 151.9 0.0 2.2e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EIM88078.1 - 3.7e-10 39.2 8.7 0.00014 21.5 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EIM88078.1 - 9.2e-05 22.2 0.7 0.0034 17.3 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 EIM88078.1 - 0.0028 18.0 4.0 0.0077 16.6 0.2 3.6 3 1 1 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EIM88078.1 - 0.0071 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats ALF PF03752.8 EIM88078.1 - 0.051 13.4 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 Short repeats of unknown function KAR9 PF08580.5 EIM88078.1 - 5.2 5.2 16.1 7.6 4.6 11.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 p450 PF00067.17 EIM88079.1 - 4.5e-62 210.0 0.0 2e-61 207.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 AAA_22 PF13401.1 EIM88079.1 - 0.073 13.2 0.2 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.21 EIM88080.1 - 1.5e-13 50.3 0.0 2.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM88080.1 - 9.5e-07 28.5 0.0 3e-06 26.9 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIM88080.1 - 0.0057 16.6 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIM88080.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GPI-anchored PF10342.4 EIM88081.1 - 5.9e-14 52.3 5.9 5.9e-14 52.3 4.1 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MSA-2c PF12238.3 EIM88081.1 - 0.28 10.8 8.9 0.41 10.2 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RAP1 PF07218.6 EIM88081.1 - 1.3 7.0 15.6 1.3 7.0 10.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EIM88081.1 - 2.1 6.5 11.2 2.3 6.4 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein QRPTase_C PF01729.14 EIM88082.1 - 1.3e-49 168.0 0.0 1.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EIM88082.1 - 1.5e-21 76.0 0.0 3.6e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SIP1 PF04938.7 EIM88083.1 - 1.5e-19 70.3 0.1 8.4e-19 67.8 0.1 1.9 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) NTR2 PF15458.1 EIM88084.1 - 0.94 8.6 4.3 0.23 10.6 0.7 1.7 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Ribosomal_L2_C PF03947.13 EIM88085.1 - 1.1e-44 151.3 1.5 1.7e-44 150.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIM88085.1 - 1.2e-24 86.0 0.6 2.1e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RIX1 PF08167.7 EIM88086.1 - 6.4e-20 71.4 1.7 6.4e-20 71.4 1.2 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.1 EIM88086.1 - 0.097 12.5 0.0 0.49 10.2 0.0 2.2 2 1 0 2 2 2 0 FANCI solenoid 2 RNA_pol_I_TF PF04090.7 EIM88087.1 - 4.8e-12 45.5 0.5 1.3e-09 37.6 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor NHR2 PF08788.6 EIM88087.1 - 0.084 12.3 1.0 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 NHR2 domain like TPR_14 PF13428.1 EIM88087.1 - 0.5 11.1 2.1 14 6.6 0.0 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Terpene_synth_C PF03936.11 EIM88088.1 - 3.5e-07 29.7 0.0 4.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TIP49 PF06068.8 EIM88089.1 - 1.7e-178 593.3 3.2 2e-178 593.1 2.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIM88089.1 - 7.9e-09 35.8 0.3 9.1e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM88089.1 - 2.5e-06 26.7 2.5 0.0031 16.5 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EIM88089.1 - 0.00021 20.2 0.2 0.00039 19.3 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EIM88089.1 - 0.00046 20.2 0.1 0.0051 16.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM88089.1 - 0.00067 19.7 0.3 0.32 11.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM88089.1 - 0.001 18.5 0.3 0.0025 17.2 0.2 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIM88089.1 - 0.0011 18.1 1.1 0.032 13.4 0.2 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIM88089.1 - 0.0027 17.4 1.3 6.5 6.4 0.0 3.7 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) TFIID-31kDa PF02291.10 EIM88089.1 - 0.079 12.7 0.2 0.2 11.4 0.2 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sec10 PF07393.6 EIM88090.1 - 1e-223 744.6 0.0 1.7e-223 743.8 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 ECH PF00378.15 EIM88091.1 - 3.1e-62 209.8 0.0 3.6e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HTH_Crp_2 PF13545.1 EIM88092.1 - 0.0072 16.0 0.1 0.0093 15.7 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF4287 PF14117.1 EIM88092.1 - 0.12 12.0 0.1 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) BTB PF00651.26 EIM88093.1 - 0.0004 20.3 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.1 EIM88096.1 - 6.6e-17 61.6 0.0 9.4e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88096.1 - 8e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88096.1 - 1.1e-12 48.2 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88096.1 - 5.6e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88096.1 - 2.3e-06 28.1 0.0 5.5e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM88096.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIM88096.1 - 9.4e-05 22.7 0.0 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIM88096.1 - 0.00018 20.8 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EIM88096.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88096.1 - 0.012 15.6 0.0 0.044 13.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIM88096.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 EIM88096.1 - 0.026 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 EIM88096.1 - 0.05 12.8 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.7 EIM88096.1 - 0.069 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Abhydrolase_2 PF02230.11 EIM88097.1 - 6.7e-54 182.6 0.0 1.1e-52 178.6 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIM88097.1 - 5e-13 49.0 0.1 6.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM88097.1 - 1.9e-09 37.7 0.4 8e-09 35.7 0.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EIM88097.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EIM88097.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Copper-bind PF00127.15 EIM88098.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RNA_pol_Rpb2_6 PF00562.23 EIM88099.1 - 2.2e-111 372.3 0.0 2.8e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIM88099.1 - 1.3e-32 112.3 0.0 2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EIM88099.1 - 2e-25 88.3 0.0 4.5e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EIM88099.1 - 5e-22 77.6 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EIM88099.1 - 1.6e-20 73.3 0.0 5.3e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIM88099.1 - 3.6e-18 65.5 0.0 2.8e-14 53.1 0.0 3.2 4 0 0 4 4 4 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EIM88099.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Nucleoporin2 PF04096.9 EIM88100.1 - 1.7e-45 154.3 0.0 3.2e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EIM88100.1 - 8.2e-28 96.9 317.5 1.8e-09 37.8 22.2 9.9 3 2 6 9 9 9 8 Nucleoporin FG repeat region Yae1_N PF09811.4 EIM88101.1 - 0.033 13.7 3.9 0.054 13.0 2.7 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal zf-H2C2_2 PF13465.1 EIM88102.1 - 1.9e-07 31.0 12.2 3.6e-05 23.8 3.8 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIM88102.1 - 2.8e-05 24.1 16.3 0.00019 21.5 2.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM88102.1 - 0.0011 19.1 11.6 0.0027 17.8 2.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EIM88102.1 - 0.0057 16.8 2.1 0.0057 16.8 1.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM88102.1 - 0.029 14.5 0.2 0.071 13.2 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Dof PF02701.10 EIM88102.1 - 0.072 13.0 1.5 0.12 12.3 0.4 1.8 2 0 0 2 2 2 0 Dof domain, zinc finger zf-C2H2_6 PF13912.1 EIM88102.1 - 0.19 11.7 3.3 0.17 11.8 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger MIP-T3 PF10243.4 EIM88102.1 - 1.2 7.5 4.4 1.2 7.5 3.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IBR PF01485.16 EIM88102.1 - 1.2 9.1 6.6 1.3 8.9 0.6 2.1 1 1 1 2 2 2 0 IBR domain Metallophos PF00149.23 EIM88103.1 - 7.4e-42 143.0 0.2 9.1e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Yae1_N PF09811.4 EIM88104.1 - 0.075 12.5 3.3 0.15 11.6 2.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal ABC_tran PF00005.22 EIM88105.1 - 3.7e-46 156.8 0.2 1.4e-22 80.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EIM88105.1 - 6.5e-20 70.7 3.7 3e-19 68.6 2.5 2.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM88105.1 - 1.3e-16 61.4 3.9 0.00096 19.2 0.1 4.5 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EIM88105.1 - 3.5e-09 36.0 0.1 0.0012 18.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIM88105.1 - 7.2e-09 35.1 1.6 0.59 9.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIM88105.1 - 2.3e-07 31.3 11.0 0.0098 16.2 2.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EIM88105.1 - 6.1e-07 28.8 5.7 0.28 10.1 0.0 4.6 4 1 0 4 4 4 3 AAA ATPase domain AAA_10 PF12846.2 EIM88105.1 - 3e-06 26.8 0.1 0.18 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EIM88105.1 - 3.3e-06 26.7 0.1 0.083 12.3 0.0 2.8 3 0 0 3 3 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EIM88105.1 - 4.8e-06 25.8 0.0 0.0039 16.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM88105.1 - 4.8e-06 26.7 0.2 0.085 13.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM88105.1 - 7.4e-06 26.0 1.2 0.022 14.7 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 EIM88105.1 - 9.4e-06 25.3 0.1 0.051 13.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EIM88105.1 - 1.6e-05 25.3 0.0 0.24 11.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIM88105.1 - 2.7e-05 24.1 0.7 0.04 13.8 0.5 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EIM88105.1 - 2.7e-05 24.9 0.9 0.41 11.4 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIM88105.1 - 6.2e-05 22.4 0.2 0.67 9.3 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EIM88105.1 - 8.2e-05 22.9 0.3 0.24 11.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EIM88105.1 - 0.00029 20.8 0.0 0.019 14.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM88105.1 - 0.00035 20.1 0.0 0.098 12.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM88105.1 - 0.0012 18.5 0.2 6.7 6.4 0.1 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIM88105.1 - 0.0016 18.3 0.0 3.5 7.5 0.0 4.2 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 EIM88105.1 - 0.002 18.2 1.5 2.6 8.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Dynamin_N PF00350.18 EIM88105.1 - 0.0024 17.7 8.3 0.52 10.0 0.1 4.2 2 2 2 4 4 3 2 Dynamin family AAA_33 PF13671.1 EIM88105.1 - 0.0026 17.6 0.2 2.9 7.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EIM88105.1 - 0.0027 17.9 1.1 5.9 7.0 0.2 3.7 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EIM88105.1 - 0.0027 17.3 0.8 3.5 7.3 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EIM88105.1 - 0.0032 17.3 5.1 0.69 9.6 0.1 3.9 4 1 1 5 5 3 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 EIM88105.1 - 0.0068 16.2 0.0 0.41 10.5 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EIM88105.1 - 0.0083 14.6 2.1 1.3 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EIM88105.1 - 0.0087 15.7 0.9 5.9 6.5 0.1 3.5 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.20 EIM88105.1 - 0.014 14.9 0.5 0.69 9.3 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arf PF00025.16 EIM88105.1 - 0.019 14.2 0.3 0.43 9.8 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family T2SE PF00437.15 EIM88105.1 - 0.021 13.7 0.0 0.57 9.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 EIM88105.1 - 0.023 13.6 0.0 5 6.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.21 EIM88105.1 - 0.036 13.5 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EIM88105.1 - 0.048 13.4 0.0 0.82 9.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 EIM88105.1 - 0.054 12.9 0.3 9.2 5.6 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EIM88105.1 - 0.059 12.6 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.15 EIM88105.1 - 0.11 11.2 2.7 2.5 6.6 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.4 EIM88105.1 - 0.38 10.2 3.7 16 4.9 0.0 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DivIC PF04977.10 EIM88105.1 - 0.44 10.0 6.0 6.4 6.3 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Gln-synt_C PF00120.19 EIM88107.1 - 6.2e-62 209.0 0.0 7.3e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EIM88107.1 - 1e-18 66.6 0.0 1.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DnaJ PF00226.26 EIM88108.1 - 1.9e-15 56.3 0.0 3.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Nop14 PF04147.7 EIM88109.1 - 2.1 6.1 19.2 3.2 5.5 13.3 1.2 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 EIM88109.1 - 6.8 4.8 8.4 11 4.2 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Clat_adaptor_s PF01217.15 EIM88111.1 - 1.8e-56 189.8 2.0 2.1e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.19 EIM88112.1 - 1.8e-15 57.5 0.0 2.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease MIB_HERC2 PF06701.8 EIM88114.1 - 0.058 13.3 0.5 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Mib_herc2 Histone PF00125.19 EIM88115.1 - 2.3e-28 98.1 0.2 4e-28 97.3 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM88115.1 - 0.0024 17.9 0.1 0.0039 17.3 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIM88115.1 - 0.24 11.4 1.1 0.38 10.8 0.2 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRAM_LAG1_CLN8 PF03798.11 EIM88116.1 - 1.2e-32 113.1 25.3 1.2e-32 113.1 17.5 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIM88116.1 - 1.5e-15 56.4 0.2 1.5e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein OATP PF03137.15 EIM88116.1 - 0.026 12.6 1.1 0.037 12.1 0.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1212 PF06738.7 EIM88118.1 - 7.2e-32 110.4 2.7 7.2e-32 110.4 1.9 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM88118.1 - 1.9e-13 50.4 13.5 1.9e-13 50.4 9.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF3295 PF11702.3 EIM88118.1 - 0.019 13.9 0.2 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Gly-zipper_Omp PF13488.1 EIM88119.1 - 0.0006 19.3 14.4 0.0006 19.3 10.0 4.3 2 2 3 5 5 5 4 Glycine zipper CsbD PF05532.7 EIM88119.1 - 0.0084 15.7 4.1 0.022 14.4 2.8 1.8 1 0 0 1 1 1 1 CsbD-like DUF2183 PF09949.4 EIM88120.1 - 6.3e-19 67.7 0.0 1.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GRP PF07172.6 EIM88121.1 - 0.17 12.3 10.7 0.38 11.2 7.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family LSM PF01423.17 EIM88122.1 - 6.7e-18 64.0 0.0 7.5e-18 63.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 EIM88123.1 - 1.1e-32 113.1 26.6 1.4e-32 112.7 18.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EIM88123.1 - 0.018 15.4 0.1 0.062 13.7 0.1 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 EIM88124.1 - 1.1e-82 277.8 0.3 1.2e-82 277.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.6 EIM88124.1 - 0.016 14.1 0.1 0.094 11.7 0.1 2.1 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Nop PF01798.13 EIM88125.1 - 1.5e-43 147.7 0.2 1.5e-43 147.7 0.2 1.5 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 EIM88125.1 - 9.9e-41 139.0 3.5 2e-40 138.0 2.5 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EIM88125.1 - 1.2e-18 66.6 0.2 5.1e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain NifU_N PF01592.11 EIM88126.1 - 6.8e-51 171.4 0.0 1.1e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain TFIID-31kDa PF02291.10 EIM88127.1 - 8.6e-31 106.4 0.0 1.1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EIM88127.1 - 0.00064 19.7 0.0 0.00097 19.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM88127.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EIM88127.1 - 0.0034 16.6 6.5 0.56 9.3 2.3 2.1 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIM88127.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated WD40 PF00400.27 EIM88128.1 - 1.8e-15 56.1 0.1 1.3e-06 28.0 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.7 EIM88128.1 - 0.00017 21.1 0.3 0.36 10.5 0.3 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Mg_trans_NIPA PF05653.9 EIM88129.1 - 1.1e-62 211.7 4.4 2.3e-59 200.8 3.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIM88129.1 - 2e-06 27.9 0.1 2e-06 27.9 0.0 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIM88129.1 - 8.7e-06 25.7 0.3 8.7e-06 25.7 0.2 3.0 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EIM88129.1 - 0.013 14.4 0.8 0.02 13.7 0.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Pkinase PF00069.20 EIM88130.1 - 2.8e-69 233.1 0.0 4.8e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88130.1 - 1.9e-31 109.1 0.0 1.1e-29 103.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIM88130.1 - 5.8e-05 22.5 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EIM88130.1 - 0.00011 21.2 1.5 0.19 10.6 0.4 3.2 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EIM88130.1 - 0.0032 17.2 0.5 0.23 11.1 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIM88130.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF605 PF04652.11 EIM88130.1 - 0.36 10.1 12.7 0.13 11.5 5.0 2.1 2 0 0 2 2 2 0 Vta1 like Senescence_reg PF04520.8 EIM88130.1 - 0.56 10.6 11.3 0.48 10.8 5.3 2.3 2 0 0 2 2 2 0 Senescence regulator HAUS6_N PF14661.1 EIM88130.1 - 3.9 6.7 8.7 0.48 9.7 2.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Methyltransf_8 PF05148.10 EIM88131.1 - 2.4e-61 207.1 0.0 3.7e-60 203.2 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 EIM88131.1 - 1.6e-06 27.9 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88131.1 - 2.5e-05 24.6 0.0 8.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88131.1 - 0.001 18.7 0.0 0.0065 16.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88131.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88131.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIM88131.1 - 0.015 15.6 0.1 0.091 13.1 0.0 2.3 2 1 0 2 2 1 0 Methyltransferase domain DUF605 PF04652.11 EIM88131.1 - 0.33 10.3 17.2 0.44 9.8 11.9 1.1 1 0 0 1 1 1 0 Vta1 like DNA_pol_viral_N PF00242.12 EIM88131.1 - 0.82 8.6 9.9 1.1 8.1 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2201_N PF13203.1 EIM88131.1 - 1.9 7.6 9.2 3.2 6.8 4.9 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Ndc1_Nup PF09531.5 EIM88131.1 - 8.5 4.6 7.9 11 4.2 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPRTase PF14681.1 EIM88133.1 - 9.5e-66 220.9 0.0 1.1e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIM88133.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 EIM88134.1 - 3.6e-48 163.8 0.0 5.3e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EIM88134.1 - 4.7e-11 43.2 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Transketolase_C PF02780.15 EIM88134.1 - 4.5e-05 23.3 0.1 0.00022 21.1 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 EIM88134.1 - 0.033 14.3 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.14 EIM88135.1 - 3.3e-92 309.7 10.9 9.6e-47 159.8 2.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 GFO_IDH_MocA PF01408.17 EIM88136.1 - 2e-21 76.7 0.0 4.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIM88136.1 - 3.5e-11 42.9 0.0 9.8e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIM88136.1 - 0.0045 17.2 0.0 0.0077 16.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIM88136.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RRM_1 PF00076.17 EIM88137.1 - 9.2e-19 66.8 0.1 5.1e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88137.1 - 3.5e-12 45.9 0.0 8.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88137.1 - 1.3e-11 44.2 0.0 4.1e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.18 EIM88138.1 - 1.6e-05 24.1 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EIM88138.1 - 0.0044 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain cNMP_binding PF00027.24 EIM88139.1 - 3e-33 113.4 0.0 3.9e-16 58.6 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIM88139.1 - 3.5e-09 35.9 0.1 7.1e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Glyoxal_oxid_N PF07250.6 EIM88141.1 - 2.9e-61 206.6 0.0 1.6e-60 204.1 0.0 2.2 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM88141.1 - 1.8e-18 66.4 0.2 3.9e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM88141.1 - 0.00014 21.5 6.5 1.1 9.1 0.0 4.7 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EIM88141.1 - 0.03 14.0 0.0 6.1 6.7 0.0 3.8 4 0 0 4 4 4 0 Kelch motif PMSR PF01625.16 EIM88142.1 - 9.7e-57 191.2 1.2 1.2e-56 190.9 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ATP_bind_3 PF01171.15 EIM88143.1 - 2.8e-18 66.0 0.0 4.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EIM88143.1 - 0.0039 17.4 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EIM88143.1 - 0.0049 16.2 1.1 0.0049 16.2 0.8 3.1 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 EIM88143.1 - 0.02 13.4 0.0 0.036 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.1 EIM88143.1 - 0.097 12.4 0.3 0.097 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ThiI PF02568.9 EIM88143.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HIPIP PF01355.12 EIM88143.1 - 0.22 11.6 8.3 2.2 8.4 1.0 3.1 3 0 0 3 3 3 0 High potential iron-sulfur protein TF_Zn_Ribbon PF08271.7 EIM88143.1 - 4.4 6.7 12.5 0.97 8.8 0.3 3.5 3 1 0 3 3 3 0 TFIIB zinc-binding DUF2616 PF11077.3 EIM88143.1 - 6.7 6.1 8.6 1.1 8.7 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PUF PF00806.14 EIM88144.1 - 6.1e-21 72.6 0.0 0.00031 20.0 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Bystin PF05291.6 EIM88145.1 - 1.4e-117 392.0 0.0 2e-117 391.4 0.0 1.1 1 0 0 1 1 1 1 Bystin Epimerase PF01370.16 EIM88146.1 - 1.4e-44 152.2 0.0 3.9e-44 150.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM88146.1 - 3.2e-10 39.1 0.0 4.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIM88146.1 - 3.1e-09 36.1 0.0 4.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIM88146.1 - 2.8e-08 33.0 0.0 0.00037 19.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EIM88146.1 - 9.1e-06 24.7 0.1 0.0018 17.2 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIM88146.1 - 3.8e-05 23.7 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIM88146.1 - 0.13 12.2 0.3 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_6 PF12697.2 EIM88147.1 - 1.7e-19 70.6 0.6 1.7e-19 70.6 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM88147.1 - 2e-05 24.3 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88147.1 - 0.00023 20.8 0.0 0.038 13.5 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Lactococcin PF04369.8 EIM88147.1 - 0.16 11.9 0.2 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Lactococcin-like family HTH_32 PF13565.1 EIM88147.1 - 0.21 12.4 0.7 0.93 10.3 0.1 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Abhydrolase_6 PF12697.2 EIM88148.1 - 6.2e-16 58.9 0.2 9.9e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM88148.1 - 2.7e-06 27.2 0.1 5.6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88148.1 - 6.4e-05 22.6 0.1 0.00023 20.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EIM88148.1 - 0.017 13.5 0.0 0.024 13.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.5 EIM88148.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 EIM88148.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2458 PF10454.4 EIM88149.1 - 8.1e-09 35.5 4.1 1.2e-08 34.9 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 EIM88149.1 - 5.6e-06 25.9 3.5 1.1e-05 24.9 2.5 1.5 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Peptidase_M16 PF00675.15 EIM88149.1 - 0.048 13.4 3.2 0.17 11.6 1.1 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF2838 PF10998.3 EIM88150.1 - 6.1e-36 122.6 9.5 6.1e-36 122.6 6.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Aft1_HRA PF11786.3 EIM88151.1 - 8.1e-10 38.8 20.3 1e-09 38.4 10.5 3.5 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.16 EIM88151.1 - 2.4e-08 33.8 2.6 4.3e-08 32.9 1.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EIM88151.1 - 9.4e-05 22.8 15.0 0.0021 18.5 10.4 3.4 1 1 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EIM88151.1 - 0.00025 20.8 3.1 0.00025 20.8 2.1 1.7 2 0 0 2 2 2 1 Basic region leucine zipper PBP1_TM PF14812.1 EIM88151.1 - 0.029 14.6 4.9 0.029 14.6 0.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3445 PF11927.3 EIM88152.1 - 1.3e-59 201.6 0.0 8.3e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) Mt_ATP-synt_D PF05873.7 EIM88153.1 - 3.3e-10 39.8 2.2 3.9e-10 39.5 1.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HJURP_mid PF12346.3 EIM88153.1 - 0.031 14.3 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat DUF2408 PF10303.4 EIM88153.1 - 0.057 13.5 0.3 0.098 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FAM110_C PF14160.1 EIM88153.1 - 0.074 13.9 0.0 0.14 13.1 0.0 1.6 1 1 0 1 1 1 0 Centrosome-associated C terminus hGDE_central PF14702.1 EIM88153.1 - 0.23 10.6 1.4 0.43 9.7 0.7 1.5 1 1 1 2 2 2 0 central domain of human glycogen debranching enzyme AHS1 PF02682.11 EIM88153.1 - 0.5 9.7 2.5 0.76 9.1 1.6 1.3 1 1 0 1 1 1 0 Allophanate hydrolase subunit 1 NPV_P10 PF05531.7 EIM88153.1 - 0.69 10.1 2.8 0.92 9.8 0.7 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Adap_comp_sub PF00928.16 EIM88154.1 - 3.3e-50 170.6 0.0 4.1e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIM88154.1 - 3.4e-05 23.5 0.0 5.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain M_domain PF12938.2 EIM88154.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 M domain of GW182 Hexokinase_2 PF03727.11 EIM88155.1 - 1.2e-66 224.4 0.0 2.7e-38 131.5 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EIM88155.1 - 4.2e-66 222.1 0.0 7.2e-66 221.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.7 EIM88155.1 - 0.0098 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) GHMP_kinases_C PF08544.8 EIM88155.1 - 0.11 12.6 0.3 4 7.6 0.0 2.5 2 0 0 2 2 2 0 GHMP kinases C terminal A_deamin PF02137.13 EIM88156.1 - 8e-71 239.1 0.0 9.8e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain ABC_tran PF00005.22 EIM88158.1 - 3.5e-16 59.7 0.1 2.7e-15 56.8 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM88158.1 - 3.7e-11 43.5 0.8 0.0001 22.3 0.4 2.2 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 EIM88158.1 - 1.5e-06 27.5 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EIM88158.1 - 6e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIM88158.1 - 0.00018 20.9 0.2 0.00041 19.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EIM88158.1 - 0.00072 18.8 0.1 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EIM88158.1 - 0.0016 17.6 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIM88158.1 - 0.0047 17.2 0.1 0.0089 16.3 0.0 1.4 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EIM88158.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EIM88158.1 - 0.011 15.2 0.1 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EIM88158.1 - 0.024 14.0 0.3 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EIM88158.1 - 0.027 14.4 0.1 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIM88158.1 - 0.034 14.4 0.3 0.12 12.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIM88158.1 - 0.053 14.3 0.9 0.09 13.5 0.2 1.8 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 EIM88158.1 - 0.053 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIM88158.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EIM88158.1 - 0.079 13.0 0.4 0.37 10.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM88158.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM88158.1 - 0.095 12.3 0.3 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EIM88158.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EIM88158.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain UQ_con PF00179.21 EIM88159.1 - 1.5e-14 53.5 0.0 3.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 EIM88159.1 - 0.0021 17.8 2.8 0.0044 16.8 1.9 1.5 1 0 0 1 1 1 1 IBR domain C1_4 PF07975.7 EIM88159.1 - 0.054 13.5 1.4 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain SPARC_Ca_bdg PF10591.4 EIM88159.1 - 0.079 12.9 1.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UBA PF00627.26 EIM88159.1 - 0.31 10.9 4.2 0.11 12.4 0.4 2.2 2 0 0 2 2 2 0 UBA/TS-N domain MFS_1 PF07690.11 EIM88160.1 - 1.9e-36 125.4 23.7 1.9e-36 125.4 16.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88160.1 - 2.1e-14 52.9 7.6 2.1e-14 52.9 5.3 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter MS_channel PF00924.13 EIM88161.1 - 5.9e-18 64.9 0.5 9.2e-18 64.3 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIM88161.1 - 0.0001 21.3 0.0 0.00023 20.2 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EIM88161.1 - 0.00014 21.0 0.1 0.00031 19.9 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIM88161.1 - 0.0012 18.5 1.1 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EIM88161.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EIM88161.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3040 PF11239.3 EIM88161.1 - 0.064 13.3 0.0 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PBP1_TM PF14812.1 EIM88161.1 - 0.072 13.3 5.9 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APG6 PF04111.7 EIM88162.1 - 0.056 12.4 17.6 0.071 12.1 12.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 LXG PF04740.7 EIM88162.1 - 1.3 8.7 15.9 7.3 6.3 6.8 2.8 1 1 0 2 2 2 0 LXG domain of WXG superfamily DUF3450 PF11932.3 EIM88162.1 - 2.4 7.3 12.5 3.3 6.9 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) tRNA-synt_2 PF00152.15 EIM88163.1 - 8.5e-90 300.9 0.0 1.3e-89 300.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIM88163.1 - 8.6e-11 41.5 0.0 3.6e-10 39.5 0.0 2.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIM88163.1 - 3.5e-08 32.9 0.1 0.0003 20.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EIM88163.1 - 0.01 15.4 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Prefoldin PF02996.12 EIM88164.1 - 3.6e-25 87.9 5.3 2.4e-21 75.6 0.7 2.9 1 1 2 3 3 3 2 Prefoldin subunit Pol_alpha_B_N PF08418.5 EIM88164.1 - 0.037 13.5 1.8 0.048 13.1 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Exonuc_VII_S PF02609.11 EIM88164.1 - 0.062 13.0 0.4 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit Syntaxin-6_N PF09177.6 EIM88164.1 - 0.13 12.6 4.2 1.8 9.0 0.5 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Methyltransf_16 PF10294.4 EIM88167.1 - 3.2e-44 150.4 0.0 4e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EIM88167.1 - 0.00016 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIM88167.1 - 0.00019 22.0 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88167.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM88167.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 EIM88167.1 - 0.037 13.4 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 BolA PF01722.13 EIM88169.1 - 1.2e-16 60.4 0.0 1.5e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein PQQ_3 PF13570.1 EIM88169.1 - 0.14 12.4 0.3 0.97 9.7 0.1 2.0 2 0 0 2 2 2 0 PQQ-like domain adh_short_C2 PF13561.1 EIM88170.1 - 2.2e-26 93.1 0.1 2.7e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM88170.1 - 3.4e-26 92.1 1.2 4.4e-26 91.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM88170.1 - 6.6e-09 35.6 0.1 1.4e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIM88170.1 - 0.00081 19.0 0.5 0.003 17.2 0.3 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EIM88170.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EIM88170.1 - 0.025 14.3 0.4 0.74 9.6 0.2 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UDPG_MGDP_dh_N PF03721.9 EIM88170.1 - 0.063 12.6 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 EIM88170.1 - 0.087 13.3 0.1 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Toxin_63 PF15541.1 EIM88170.1 - 0.095 12.6 0.0 0.42 10.5 0.0 1.9 1 1 1 2 2 2 0 Putative toxin 63 DUF962 PF06127.6 EIM88171.1 - 4.7e-24 84.1 3.7 2.5e-23 81.7 2.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.1 EIM88172.1 - 1.2e-27 95.3 0.1 1.7e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIM88172.1 - 1.3e-14 53.5 0.0 2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin SKG6 PF08693.5 EIM88172.1 - 1.1 8.6 3.4 1.8 7.9 2.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4646 PF15496.1 EIM88173.1 - 1.7e-16 60.3 0.8 1.7e-16 60.3 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) DDHD PF02862.12 EIM88173.1 - 0.21 11.3 4.6 4.4 7.0 0.4 2.1 2 0 0 2 2 2 0 DDHD domain CAF-1_p150 PF11600.3 EIM88173.1 - 0.3 10.4 26.6 0.056 12.8 4.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 EIM88173.1 - 1.7 8.0 31.4 1.1 8.7 3.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein IF-2B PF01008.12 EIM88174.1 - 2.1e-84 282.8 0.1 2.7e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DDE_Tnp_IS66 PF03050.9 EIM88174.1 - 0.09 11.9 0.1 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Transposase IS66 family Fork_head PF00250.13 EIM88175.1 - 6.7e-22 77.3 0.1 1.8e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EIM88175.1 - 9.2e-07 28.8 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF3781 PF12636.2 EIM88175.1 - 0.01 15.7 0.6 0.094 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) MTP18 PF10558.4 EIM88176.1 - 5.4e-57 191.8 0.4 6.6e-57 191.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Nuf2 PF03800.9 EIM88177.1 - 5.3e-26 91.3 2.1 7.4e-26 90.8 0.1 2.2 2 0 0 2 2 2 1 Nuf2 family DUF3584 PF12128.3 EIM88177.1 - 0.68 7.1 42.9 0.33 8.2 28.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 EIM88177.1 - 1.2 8.4 42.5 0.067 12.6 6.0 2.9 1 1 2 3 3 3 0 Intermediate filament protein DUF2373 PF10180.4 EIM88178.1 - 2.7e-15 55.6 0.7 5.4e-15 54.6 0.3 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) MIP-T3 PF10243.4 EIM88178.1 - 0.031 12.7 46.5 0.044 12.2 32.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_71 PF03659.9 EIM88179.1 - 1.5e-87 293.6 1.9 1.8e-87 293.3 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Aminotran_1_2 PF00155.16 EIM88180.1 - 4.8e-77 259.3 0.0 6.3e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIM88180.1 - 0.00014 20.7 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIM88180.1 - 0.00098 17.5 0.0 0.0019 16.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIM88180.1 - 0.025 13.6 0.0 0.084 11.9 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SR-25 PF10500.4 EIM88180.1 - 2.9 7.3 6.2 5 6.5 3.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aminotran_3 PF00202.16 EIM88181.1 - 2.2e-88 296.3 0.0 2.6e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ATP-grasp_4 PF13535.1 EIM88182.1 - 7.1e-08 32.3 0.1 1.6e-05 24.7 0.1 3.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIM88182.1 - 9.6e-08 31.1 0.0 5e-05 22.1 0.0 3.4 2 1 1 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EIM88182.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain NAD_binding_4 PF07993.7 EIM88183.1 - 5.2e-41 140.2 0.0 2.7e-40 137.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EIM88183.1 - 9.1e-26 90.1 0.0 6.3e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM88183.1 - 3.3e-11 43.0 0.0 5.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM88183.1 - 2e-06 27.9 0.0 5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIM88183.1 - 0.00025 20.9 1.4 0.00025 20.9 0.9 2.1 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM88183.1 - 0.00047 19.1 0.1 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EIM88183.1 - 0.0006 19.5 0.9 0.0019 17.9 0.6 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIM88183.1 - 0.00081 18.1 0.0 0.0028 16.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIM88183.1 - 0.00097 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 EIM88183.1 - 0.023 15.6 0.1 0.43 11.5 0.1 2.9 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain NmrA PF05368.8 EIM88183.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Pox_G5 PF04599.7 EIM88183.1 - 0.41 9.3 0.0 0.69 8.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein Methyltransf_3 PF01596.12 EIM88184.1 - 1.9e-40 138.1 0.0 2.7e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIM88184.1 - 6e-08 33.4 0.0 1.6e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88184.1 - 0.00014 22.3 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EIM88184.1 - 0.0044 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Cons_hypoth95 PF03602.10 EIM88184.1 - 0.032 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CmcI PF04989.7 EIM88184.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Peptidase_S55 PF05580.7 EIM88184.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 SpoIVB peptidase S55 DHQ_synthase PF01761.15 EIM88185.1 - 1.9e-52 177.7 0.0 2.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EIM88185.1 - 1.6e-13 50.5 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EIM88185.1 - 0.00013 20.7 0.0 0.00041 19.0 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Cpn60_TCP1 PF00118.19 EIM88185.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family cwf21 PF08312.7 EIM88186.1 - 1.3e-12 47.3 11.3 1.3e-12 47.3 7.8 2.7 3 0 0 3 3 3 1 cwf21 domain Flavokinase PF01687.12 EIM88187.1 - 6.6e-36 122.9 0.0 7.9e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Bromo_TP PF07524.8 EIM88188.1 - 4.2e-10 39.2 0.0 6.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EIM88188.1 - 8.8e-06 25.6 2.7 2.8e-05 24.0 1.9 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term DUF3622 PF12286.3 EIM88188.1 - 0.084 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) Myb_DNA-binding PF00249.26 EIM88189.1 - 3e-43 145.6 2.6 3e-15 55.9 0.1 5.6 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM88189.1 - 4.7e-36 122.7 1.8 1.2e-14 54.1 0.0 5.4 3 1 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIM88189.1 - 4.8e-06 26.6 3.6 1.4 9.0 0.1 4.7 4 0 0 4 4 4 3 Myb/SANT-like DNA-binding domain DUF1115 PF06544.7 EIM88190.1 - 1.4e-20 73.3 0.0 2.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Asp PF00026.18 EIM88191.1 - 9.5e-76 255.0 2.7 1.3e-75 254.6 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM88191.1 - 8.5e-05 22.5 2.0 0.00053 19.9 0.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM88191.1 - 0.00067 19.2 0.5 0.0024 17.4 0.4 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIM88191.1 - 0.019 15.4 5.2 0.82 10.2 0.5 3.5 2 2 0 2 2 2 0 Aspartyl protease Ribosomal_L13 PF00572.13 EIM88193.1 - 4.4e-47 159.3 0.2 5.3e-47 159.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 adh_short PF00106.20 EIM88195.1 - 0.0055 16.6 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM88195.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase MT-A70 PF05063.9 EIM88196.1 - 9.7e-56 188.0 0.0 1.3e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Abhydrolase_6 PF12697.2 EIM88198.1 - 4.5e-33 115.0 0.5 6.9e-33 114.4 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88198.1 - 2.3e-18 66.6 0.0 1.3e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM88198.1 - 7.3e-17 61.4 0.0 5.6e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EIM88198.1 - 5.4e-06 26.0 0.3 1.3e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EIM88198.1 - 6.5e-05 22.5 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EIM88198.1 - 0.00079 17.9 0.0 0.002 16.6 0.0 1.6 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.8 EIM88198.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 EIM88198.1 - 0.0036 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EIM88198.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 EIM88198.1 - 0.0086 15.7 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 EIM88198.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 EIM88198.1 - 0.024 13.7 0.0 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 EIM88198.1 - 0.072 12.5 0.0 0.51 9.7 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 EIM88198.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ribosomal_S11 PF00411.14 EIM88199.1 - 7.6e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.7 EIM88200.1 - 1.5e-18 66.1 4.4 1.8e-18 65.8 3.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.11 EIM88201.1 - 9.8e-50 168.9 0.0 1.9e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arf PF00025.16 EIM88204.1 - 5.8e-72 240.5 0.0 6.8e-72 240.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM88204.1 - 4.9e-15 55.1 0.0 6.9e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIM88204.1 - 2.7e-14 52.6 0.4 6.7e-10 38.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIM88204.1 - 7.1e-11 41.6 0.0 8.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIM88204.1 - 1.1e-10 41.1 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM88204.1 - 4.2e-09 36.9 0.0 5.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIM88204.1 - 4.8e-05 23.2 0.0 6.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIM88204.1 - 0.017 14.5 0.0 0.1 12.0 0.0 1.9 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EIM88205.1 - 2.2e-27 93.9 11.2 1.7e-09 37.1 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EIM88205.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Iso_dh PF00180.15 EIM88206.1 - 4.1e-101 338.4 0.0 4.7e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1237 PF06824.6 EIM88208.1 - 1.1e-142 475.6 0.4 1.2e-142 475.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) UCH_1 PF13423.1 EIM88208.1 - 0.041 13.3 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cobalamin_bind PF01122.14 EIM88208.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein C2 PF00168.25 EIM88209.1 - 3.1e-10 39.7 0.0 6.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Peptidase_M28 PF04389.12 EIM88211.1 - 1.4e-25 90.0 0.1 2.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIM88211.1 - 3.7e-07 29.8 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.14 EIM88212.1 - 4.3e-27 94.0 0.0 7.4e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EIM88212.1 - 1.7e-25 88.2 0.1 2.7e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Glyco_hydro_cc PF11790.3 EIM88215.1 - 5.5e-57 192.9 9.5 8.3e-57 192.3 6.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.17 EIM88216.1 - 2.7e-28 97.3 0.0 1.7e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88216.1 - 9.8e-21 73.5 0.0 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88216.1 - 5.6e-12 45.3 0.0 7.5e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIM88216.1 - 0.00033 20.3 2.0 1.3 8.8 0.1 3.1 2 1 0 2 2 2 2 Limkain b1 DbpA PF03880.10 EIM88216.1 - 0.0092 15.6 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain NIL PF09383.5 EIM88216.1 - 0.058 12.9 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 NIL domain OB_RNB PF08206.6 EIM88216.1 - 0.09 12.3 1.7 12 5.4 0.0 3.2 2 1 0 2 2 2 0 Ribonuclease B OB domain Menin PF05053.8 EIM88216.1 - 0.37 8.9 8.5 0.43 8.6 5.9 1.1 1 0 0 1 1 1 0 Menin Med3 PF11593.3 EIM88216.1 - 3.1 6.9 10.3 4.4 6.4 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4187 PF13821.1 EIM88217.1 - 1.6e-20 72.4 1.3 4e-20 71.1 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EIM88217.1 - 1.3e-06 28.0 0.3 1.3e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EIM88217.1 - 3.7 7.4 7.3 2.3 8.1 2.8 2.5 2 1 0 2 2 2 0 DExH-box splicing factor binding site DNA_RNApol_7kD PF03604.8 EIM88219.1 - 1.1e-17 63.2 7.4 1.3e-17 62.9 5.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EIM88219.1 - 0.0015 18.2 0.4 0.0017 18.0 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIM88219.1 - 0.0015 18.3 0.7 0.0022 17.7 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ISL3 PF14690.1 EIM88219.1 - 0.0022 17.9 2.1 0.012 15.5 0.4 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.6 EIM88219.1 - 0.0068 16.0 0.9 0.009 15.6 0.6 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C3HC PF07967.8 EIM88219.1 - 0.009 15.7 0.1 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 C3HC zinc finger-like NinF PF05810.7 EIM88219.1 - 0.018 14.8 0.3 0.024 14.4 0.2 1.2 1 0 0 1 1 1 0 NinF protein DUF2296 PF10058.4 EIM88219.1 - 0.02 14.6 0.4 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_2 PF13240.1 EIM88219.1 - 0.02 14.3 0.6 0.1 12.1 0.6 1.9 1 1 1 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EIM88219.1 - 0.027 14.7 3.9 0.26 11.5 0.6 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 EIM88219.1 - 0.028 14.3 3.1 0.069 13.1 2.1 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EIM88219.1 - 0.03 13.5 0.4 5 6.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EIM88219.1 - 0.048 13.6 1.0 1.9 8.4 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-trcl PF13451.1 EIM88219.1 - 0.059 13.0 6.3 1.4 8.5 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain TF_Zn_Ribbon PF08271.7 EIM88219.1 - 0.13 11.5 2.9 1.3 8.3 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 EIM88219.1 - 0.15 11.6 2.1 1.3 8.6 1.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Cas_CXXC_CXXC PF09706.5 EIM88219.1 - 0.17 12.0 3.9 5.5 7.2 0.4 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Mu-like_Com PF10122.4 EIM88219.1 - 0.18 10.9 4.5 2.9 7.0 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com TFIIS_C PF01096.13 EIM88219.1 - 0.19 11.3 2.0 3.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-NADH-PPase PF09297.6 EIM88219.1 - 0.29 10.6 3.1 1.1 8.8 2.2 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_6 PF14599.1 EIM88219.1 - 0.31 10.8 1.7 1.5 8.6 1.2 1.9 1 1 1 2 2 2 0 Zinc-ribbon GATA PF00320.22 EIM88219.1 - 0.31 10.4 2.0 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 GATA zinc finger DUF2197 PF09963.4 EIM88219.1 - 0.37 10.7 4.6 2.3 8.2 0.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zinc_ribbon_4 PF13717.1 EIM88219.1 - 0.39 10.4 2.7 4.8 6.9 1.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 EIM88219.1 - 0.44 10.5 5.3 3.1 7.8 1.7 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Zn_Tnp_IS1595 PF12760.2 EIM88219.1 - 0.59 9.9 4.2 2.3 8.0 2.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EIM88219.1 - 0.71 9.4 3.1 3.5 7.2 1.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF35_N PF12172.3 EIM88219.1 - 1 9.3 3.5 3.3 7.7 0.1 2.5 3 0 0 3 3 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) UPF0547 PF10571.4 EIM88219.1 - 4.8 6.9 5.4 2.2 8.0 0.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF3425 PF11905.3 EIM88221.1 - 7.4e-18 64.7 0.9 1.1e-15 57.6 0.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIM88221.1 - 3.8e-09 36.3 2.3 3.8e-09 36.3 1.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIM88221.1 - 0.00065 19.4 6.8 0.0018 18.0 2.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper COX14 PF14880.1 EIM88222.1 - 0.085 12.4 0.5 0.25 10.9 0.1 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c assembly MFS_1 PF07690.11 EIM88223.1 - 2.5e-32 111.9 47.6 7.7e-28 97.2 20.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EIM88225.1 - 2.3e-68 230.1 0.0 3.1e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88225.1 - 2.3e-29 102.2 0.0 2e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM88225.1 - 9.1e-10 37.9 0.1 3.2e-06 26.3 0.0 3.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EIM88225.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.12 EIM88226.1 - 4.3e-20 71.8 0.0 6.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE_assoc PF09335.6 EIM88227.1 - 7e-13 48.8 7.4 9.3e-13 48.4 4.3 1.8 1 1 1 2 2 2 1 SNARE associated Golgi protein Ribosomal_L29 PF00831.18 EIM88228.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein PEX11 PF05648.9 EIM88229.1 - 2e-13 50.1 1.3 2.3e-07 30.2 0.2 2.2 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.8 EIM88230.1 - 2.2e-11 43.4 0.0 2.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DOT1 PF08123.8 EIM88231.1 - 0.061 12.6 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TPMT PF05724.6 EIM88232.1 - 1.2e-25 90.2 0.0 1.5e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 EIM88232.1 - 7.3e-05 22.7 0.0 0.00016 21.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88232.1 - 0.00021 20.8 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88232.1 - 0.00024 21.5 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88232.1 - 0.0003 21.2 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EIM88233.1 - 1.3e-32 112.9 0.0 1.7e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 EIM88233.1 - 2e-08 34.6 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88233.1 - 4.1e-08 32.9 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88233.1 - 4.2e-08 33.2 0.0 6.2e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88233.1 - 4.3e-08 33.5 0.0 6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88233.1 - 8.6e-08 32.7 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM88233.1 - 2.7e-06 27.6 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM88233.1 - 4.2e-06 26.5 0.0 5.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF3081 PF11280.3 EIM88233.1 - 0.097 12.2 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) TehB PF03848.9 EIM88233.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PPR_2 PF13041.1 EIM88234.1 - 6.3e-06 26.0 0.0 0.0017 18.2 0.0 2.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EIM88234.1 - 0.0079 16.4 0.3 7.4 7.1 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain DUF515 PF04415.7 EIM88234.1 - 6.5 4.8 6.0 17 3.5 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Methyltransf_23 PF13489.1 EIM88235.1 - 2.5e-19 69.5 0.6 5.3e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88235.1 - 3.8e-17 62.2 0.2 6.3e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88235.1 - 7e-14 52.0 0.1 1.7e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88235.1 - 1.2e-12 48.1 0.1 4.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88235.1 - 6.5e-12 46.0 0.1 1.1e-11 45.2 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88235.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM88235.1 - 1.4e-09 38.1 0.2 8.1e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM88235.1 - 1.3e-07 30.9 0.0 2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIM88235.1 - 2.1e-07 30.5 0.0 4.7e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIM88235.1 - 4.2e-05 22.8 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EIM88235.1 - 7.4e-05 22.8 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 EIM88235.1 - 0.0006 19.2 0.0 0.00091 18.6 0.0 1.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.6 EIM88235.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EIM88235.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIM88235.1 - 0.026 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EIM88235.1 - 0.066 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2312 PF10073.4 EIM88235.1 - 0.083 12.2 0.8 0.95 8.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DREV PF05219.7 EIM88235.1 - 0.091 11.6 0.0 0.12 11.2 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase AAA PF00004.24 EIM88236.1 - 4.3e-30 104.6 0.0 7.2e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM88236.1 - 8.8e-08 32.3 0.2 4.5e-07 30.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EIM88236.1 - 1.3e-06 29.2 0.0 2.8e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM88236.1 - 2.4e-06 27.6 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EIM88236.1 - 4.2e-06 26.6 0.0 2.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIM88236.1 - 1.5e-05 24.8 0.0 4.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM88236.1 - 1.7e-05 24.5 0.1 0.00053 19.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIM88236.1 - 2.4e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIM88236.1 - 5.5e-05 22.6 0.2 0.089 12.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.1 EIM88236.1 - 0.00013 21.5 0.0 0.00028 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIM88236.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EIM88236.1 - 0.001 18.0 0.0 0.052 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EIM88236.1 - 0.0011 19.0 0.0 0.0035 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIM88236.1 - 0.0011 18.5 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIM88236.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 EIM88236.1 - 0.0017 18.0 0.0 0.16 11.6 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EIM88236.1 - 0.0018 18.0 0.1 0.0057 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIM88236.1 - 0.0023 17.6 0.1 0.0056 16.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EIM88236.1 - 0.003 17.7 0.0 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EIM88236.1 - 0.0033 16.8 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EIM88236.1 - 0.0041 16.1 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EIM88236.1 - 0.0048 15.6 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Viral_helicase1 PF01443.13 EIM88236.1 - 0.005 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIM88236.1 - 0.021 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIM88236.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_23 PF13476.1 EIM88236.1 - 0.026 14.8 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM88236.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EIM88236.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EIM88236.1 - 0.085 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EIM88236.1 - 0.087 11.9 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EIM88236.1 - 0.09 12.0 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.4 EIM88236.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EIM88236.1 - 0.12 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EIM88236.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rdx PF10262.4 EIM88237.1 - 3.3e-23 81.4 0.0 3.9e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.3 EIM88238.1 - 2e-72 243.2 2.2 9.2e-64 214.9 0.3 4.1 3 1 1 4 4 4 3 CLASP N terminal HEAT PF02985.17 EIM88238.1 - 1.3e-05 24.8 0.3 6.9 7.0 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EIM88238.1 - 0.00062 20.0 6.6 0.77 10.0 0.0 5.2 5 2 2 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EIM88238.1 - 0.043 14.3 3.3 11 6.6 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Cnd1 PF12717.2 EIM88238.1 - 0.091 12.6 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Rhomboid PF01694.17 EIM88239.1 - 6.7e-22 78.0 9.9 1.3e-21 77.1 6.9 1.5 1 0 0 1 1 1 1 Rhomboid family Sedlin_N PF04628.8 EIM88240.1 - 1.6e-40 137.9 0.0 2.1e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EIM88240.1 - 3.1e-09 36.6 0.1 4.8e-09 36.0 0.0 1.4 2 0 0 2 2 2 1 Sybindin-like family ThiG PF05690.9 EIM88241.1 - 0.012 14.6 2.7 0.029 13.4 0.2 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG CLPTM1 PF05602.7 EIM88241.1 - 0.25 9.9 4.0 0.29 9.7 2.8 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Med15 PF09606.5 EIM88241.1 - 0.36 8.9 50.4 0.41 8.7 35.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 EIM88241.1 - 0.77 10.0 7.9 1.1 9.5 5.5 1.3 1 0 0 1 1 1 0 AAA domain SOBP PF15279.1 EIM88241.1 - 3 8.1 15.3 4.1 7.7 10.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Actin PF00022.14 EIM88243.1 - 2.8e-112 375.0 0.0 3.2e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIM88243.1 - 4.9e-07 28.6 0.0 0.00053 18.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EIM88243.1 - 0.0099 15.7 0.0 3.6 7.4 0.0 2.6 3 0 0 3 3 3 2 Cell division protein FtsA BOP1NT PF08145.7 EIM88244.1 - 3.9e-99 331.6 7.2 5.3e-99 331.1 5.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EIM88244.1 - 2.4e-22 77.9 6.9 3.8e-07 29.7 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIM88244.1 - 0.038 13.4 0.0 10 5.7 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1939 PF09154.5 EIM88244.1 - 0.038 13.8 0.1 0.29 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1939) DUF1772 PF08592.6 EIM88245.1 - 0.02 14.6 1.2 0.02 14.6 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2423 PF10338.4 EIM88246.1 - 7.1e-14 51.5 4.5 7.1e-14 51.5 3.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Laps PF10169.4 EIM88246.1 - 0.25 11.5 4.7 0.67 10.1 3.2 1.8 1 1 0 1 1 1 0 Learning-associated protein DUF2890 PF11081.3 EIM88246.1 - 0.49 10.4 5.2 0.65 10.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Glyco_hydro_16 PF00722.16 EIM88247.1 - 2.2e-16 59.6 1.1 3.4e-16 59.0 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nop10p PF04135.7 EIM88247.1 - 0.0057 16.3 0.1 0.16 11.6 0.0 2.6 3 0 0 3 3 3 1 Nucleolar RNA-binding protein, Nop10p family RRM_1 PF00076.17 EIM88248.1 - 9.4e-17 60.4 0.0 2e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.15 EIM88248.1 - 8.6e-16 57.7 0.0 2.9e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L19 RRM_6 PF14259.1 EIM88248.1 - 1.3e-14 53.8 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88248.1 - 9.6e-06 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARD PF03079.9 EIM88249.1 - 0.00056 19.8 1.1 0.00087 19.2 0.8 1.2 1 0 0 1 1 1 1 ARD/ARD' family Glyco_hydro_66 PF13199.1 EIM88249.1 - 0.0013 17.2 0.3 0.0018 16.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 IMD PF08397.6 EIM88249.1 - 0.0078 15.5 2.7 0.015 14.5 1.9 1.4 1 1 0 1 1 1 1 IRSp53/MIM homology domain GrpE PF01025.14 EIM88249.1 - 0.07 12.6 1.6 0.12 11.8 1.1 1.3 1 0 0 1 1 1 0 GrpE tRNA-synt_2 PF00152.15 EIM88250.1 - 1.3e-101 339.7 0.0 7.4e-54 182.7 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIM88250.1 - 5.3e-07 29.4 0.0 1.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EIM88250.1 - 0.00039 20.0 0.1 0.013 15.0 0.1 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) F-box PF00646.28 EIM88251.1 - 0.001 18.6 0.7 0.0029 17.2 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM88251.1 - 0.021 14.5 1.3 0.054 13.2 0.9 1.8 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 EIM88251.1 - 0.069 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 F-box-like domain ACPS PF01648.15 EIM88252.1 - 3.5e-12 46.1 0.0 5.8e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.19 EIM88253.1 - 3.3e-16 59.2 0.0 5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EIM88253.1 - 0.0063 15.7 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase LSM PF01423.17 EIM88254.1 - 1.3e-19 69.4 0.0 1.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIM88254.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Fungal_trans PF04082.13 EIM88255.1 - 3.5e-33 114.6 0.0 5e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM88255.1 - 2.3e-09 36.9 11.6 4.2e-09 36.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EIM88256.1 - 1.8e-30 105.9 0.6 2.7e-30 105.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EIM88256.1 - 3.7e-14 53.1 1.4 5.7e-14 52.5 0.5 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIM88256.1 - 9.6e-14 50.6 0.1 3.8e-13 48.7 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIM88256.1 - 3.7e-10 40.3 0.0 1.1e-09 38.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SIR2 PF02146.12 EIM88257.1 - 3.1e-33 114.9 0.0 3.2e-31 108.4 0.0 2.2 1 1 0 1 1 1 1 Sir2 family SIR2_2 PF13289.1 EIM88257.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 SIR2-like domain PNTB PF02233.11 EIM88257.1 - 0.1 11.3 0.0 2.2 6.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.17 EIM88257.1 - 0.11 12.3 0.0 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Complex1_LYR_2 PF13233.1 EIM88258.1 - 1.9e-08 34.7 0.0 2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like WD40 PF00400.27 EIM88259.1 - 5.7e-61 200.3 26.1 4.7e-10 38.9 0.7 9.9 10 0 0 10 10 10 8 WD domain, G-beta repeat eIF2A PF08662.6 EIM88259.1 - 0.048 13.3 0.1 21 4.7 0.1 3.0 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EIM88259.1 - 0.094 12.2 0.1 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pet191_N PF10203.4 EIM88260.1 - 1.6e-24 85.6 5.5 2e-24 85.4 3.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NGP1NT PF08153.7 EIM88260.1 - 0.035 14.0 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 NGP1NT (NUC091) domain Cmc1 PF08583.5 EIM88260.1 - 0.19 11.5 5.0 5.1 6.9 0.1 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIM88260.1 - 0.27 11.2 2.9 5.2 7.1 0.4 2.4 2 0 0 2 2 2 0 CHCH domain GCV_T PF01571.16 EIM88261.1 - 9.1e-15 54.5 0.0 4e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIM88261.1 - 0.0068 16.4 0.0 0.026 14.5 0.0 2.0 2 1 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain ACPS PF01648.15 EIM88262.1 - 8.9e-13 48.0 0.0 1.9e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NAD_Gly3P_dh_C PF07479.9 EIM88263.1 - 3.3e-44 150.2 0.1 5.1e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIM88263.1 - 6e-33 113.8 0.0 9.4e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EIM88263.1 - 3.4e-07 29.8 0.0 6.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIM88263.1 - 0.00092 19.5 0.0 0.0039 17.5 0.0 2.1 2 1 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIM88263.1 - 0.0023 17.8 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase VARLMGL PF14383.1 EIM88263.1 - 0.0059 15.7 1.0 0.014 14.5 0.7 1.6 1 0 0 1 1 1 1 DUF761-associated sequence motif Saccharop_dh PF03435.13 EIM88263.1 - 0.018 14.0 0.0 0.034 13.1 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIM88263.1 - 0.023 14.6 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EIM88263.1 - 0.024 14.2 0.0 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIM88263.1 - 0.13 12.2 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIM88263.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Hydrolase_3 PF08282.7 EIM88264.1 - 5.8e-42 144.0 0.0 7.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIM88264.1 - 1.1e-10 41.2 0.0 9.2e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EIM88264.1 - 1.7e-05 25.3 0.1 0.87 9.9 0.1 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM88264.1 - 0.00085 19.5 0.1 0.14 12.3 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIM88264.1 - 0.021 14.7 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM88264.1 - 0.05 13.8 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AKAP95 PF04988.7 EIM88264.1 - 0.064 13.0 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF2608 PF11019.3 EIM88264.1 - 0.17 10.8 0.1 0.48 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) DUF1640 PF07798.6 EIM88265.1 - 2.5e-12 47.1 5.6 3.1e-12 46.8 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Ribosomal_S9 PF00380.14 EIM88265.1 - 0.11 12.7 0.4 0.18 12.0 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF4404 PF14357.1 EIM88265.1 - 0.49 10.8 4.4 0.97 9.8 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Pheromone PF08015.6 EIM88265.1 - 8.6 7.2 8.6 4.5 8.1 3.4 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone ATP_bind_1 PF03029.12 EIM88266.1 - 4.1e-76 255.6 0.0 5.1e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EIM88266.1 - 6.3e-06 25.7 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EIM88266.1 - 1.4e-05 25.9 0.0 2.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EIM88266.1 - 0.00021 20.4 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_29 PF13555.1 EIM88266.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM88266.1 - 0.0018 18.3 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM88266.1 - 0.0022 18.0 0.0 0.0063 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIM88266.1 - 0.0036 17.1 0.0 0.0079 16.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 EIM88266.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.10 EIM88266.1 - 0.01 15.5 0.1 0.024 14.3 0.0 1.6 2 0 0 2 2 1 0 NTPase AAA_19 PF13245.1 EIM88266.1 - 0.017 14.8 0.3 0.073 12.8 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EIM88266.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 EIM88266.1 - 0.019 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 EIM88266.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 EIM88266.1 - 0.026 14.2 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIM88266.1 - 0.026 14.8 0.0 0.05 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIM88266.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.11 EIM88266.1 - 0.039 13.1 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EIM88266.1 - 0.05 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EIM88266.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIM88266.1 - 0.053 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EIM88266.1 - 0.059 12.3 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MipZ PF09140.6 EIM88266.1 - 0.06 12.4 0.0 8.9 5.3 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ AAA_30 PF13604.1 EIM88266.1 - 0.068 12.7 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIM88266.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EIM88266.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIM88266.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EIM88266.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF566 PF04484.7 EIM88268.1 - 4.5 6.6 9.1 5.1 6.5 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dynamin_N PF00350.18 EIM88269.1 - 1e-16 61.2 7.1 1.5e-16 60.6 0.0 3.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EIM88269.1 - 1.7e-05 24.7 0.1 0.0019 18.1 0.1 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM88269.1 - 0.0034 16.5 0.0 0.032 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIM88269.1 - 0.0053 16.2 0.0 0.0053 16.2 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EIM88269.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EIM88269.1 - 0.0096 15.9 1.7 0.12 12.3 0.0 3.2 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EIM88269.1 - 0.021 14.9 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIM88269.1 - 0.036 14.3 0.2 0.036 14.3 0.1 3.9 2 1 1 3 3 1 0 AAA domain AAA_29 PF13555.1 EIM88269.1 - 0.045 13.2 0.2 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.10 EIM88269.1 - 0.097 11.3 0.0 0.34 9.5 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein EzrA PF06160.7 EIM88269.1 - 0.14 10.2 16.4 0.067 11.3 3.0 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.9 EIM88269.1 - 0.64 9.6 15.8 1.3 8.6 0.5 4.7 5 0 0 5 5 5 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 EIM88269.1 - 6.1 6.6 13.1 0.19 11.5 0.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EIM88269.1 - 8.1 4.1 14.4 3 5.5 3.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 EIM88271.1 - 1.1e-36 126.3 20.5 1.1e-36 126.3 14.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Thiolase_N PF00108.18 EIM88272.1 - 3.7e-91 304.7 2.2 5.1e-91 304.3 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIM88272.1 - 1.8e-38 130.7 4.5 1.8e-38 130.7 0.4 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIM88272.1 - 1.2e-05 24.9 0.8 3.2e-05 23.5 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIM88272.1 - 1.9 8.2 7.9 0.47 10.1 0.2 3.0 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Autophagy_act_C PF03987.10 EIM88273.1 - 1.5e-11 44.2 1.2 2.5e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.13 EIM88274.1 - 3.1e-83 277.8 3.2 3.7e-83 277.6 2.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EIM88274.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region mRNA_cap_C PF03919.10 EIM88274.1 - 0.087 13.1 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Glyco_hydro_47 PF01532.15 EIM88275.1 - 8.5e-136 453.1 0.0 1e-135 452.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 EIM88275.1 - 1.3e-06 28.0 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 EIM88276.1 - 1.7e-16 59.6 2.2 6.7e-10 38.5 0.0 2.7 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DRP PF06044.7 EIM88276.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Dam-replacing family YhfH PF14149.1 EIM88276.1 - 0.45 10.3 2.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-RING_2 PF13639.1 EIM88278.1 - 6.4e-07 29.0 9.8 1.1e-06 28.3 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM88278.1 - 1.3e-05 24.7 9.9 2.4e-05 23.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM88278.1 - 0.00013 21.6 11.1 0.00024 20.7 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF904 PF06005.7 EIM88278.1 - 0.00064 19.9 5.1 0.24 11.7 1.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF904) zf-C3HC4_2 PF13923.1 EIM88278.1 - 0.0018 18.2 10.7 0.0033 17.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TSC22 PF01166.13 EIM88278.1 - 0.003 17.4 1.4 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 TSC-22/dip/bun family zf-C3HC4_4 PF15227.1 EIM88278.1 - 0.0095 15.7 12.6 0.017 14.9 8.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1049 PF06305.6 EIM88278.1 - 0.016 14.6 3.7 0.98 8.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DivIC PF04977.10 EIM88278.1 - 0.018 14.5 6.3 1.7 8.1 0.8 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF4618 PF15397.1 EIM88278.1 - 0.028 13.7 5.5 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) zf-RING_6 PF14835.1 EIM88278.1 - 0.28 10.9 6.2 0.56 10.0 4.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EIM88278.1 - 0.61 9.7 11.8 1.2 8.7 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.1 EIM88278.1 - 0.96 8.3 10.1 0.073 12.0 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Rab5-bind PF09311.6 EIM88278.1 - 1.1 9.0 13.9 0.34 10.7 1.1 3.2 3 1 0 3 3 3 0 Rabaptin-like protein DivIVA PF05103.8 EIM88278.1 - 2.1 8.3 11.9 0.46 10.5 0.1 3.0 3 0 0 3 3 3 0 DivIVA protein IncA PF04156.9 EIM88278.1 - 2.3 7.7 13.8 0.7 9.4 0.1 2.9 2 1 0 3 3 3 0 IncA protein DUF972 PF06156.8 EIM88278.1 - 3.6 7.9 13.6 1.2 9.5 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-RING_UBOX PF13445.1 EIM88278.1 - 7 6.4 10.6 19 5.0 7.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger V_ATPase_I PF01496.14 EIM88278.1 - 7.1 4.3 5.6 24 2.6 3.7 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EIM88278.1 - 7.8 6.2 13.1 1.4 8.6 0.2 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper Lge1 PF11488.3 EIM88278.1 - 9.6 6.4 17.0 0.58 10.3 0.3 3.3 3 1 1 4 4 3 0 Transcriptional regulatory protein LGE1 RhoGEF PF00621.15 EIM88279.1 - 1e-34 120.0 0.0 2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain IFT20 PF14931.1 EIM88279.1 - 0.059 13.2 2.0 0.19 11.6 1.4 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 BMFP PF04380.8 EIM88279.1 - 1.8 8.7 12.0 5.3 7.2 4.9 2.7 1 1 1 2 2 2 0 Membrane fusogenic activity GFO_IDH_MocA PF01408.17 EIM88280.1 - 6.7e-17 62.1 0.1 1.2e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIM88280.1 - 0.047 14.0 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.2 EIM88283.1 - 1.9e-23 83.0 0.0 3.2e-23 82.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIM88283.1 - 3.7e-10 39.7 0.1 7.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIM88283.1 - 3.3e-06 26.4 0.0 5.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 EIM88283.1 - 0.047 12.6 0.1 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II THOC7 PF05615.8 EIM88284.1 - 2.7e-20 73.0 1.7 4.9e-20 72.2 1.2 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 FAM101 PF15068.1 EIM88284.1 - 0.059 12.8 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 FAM101 family DUF202 PF02656.10 EIM88285.1 - 2.4e-13 50.0 1.2 2.4e-13 50.0 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EIM88285.1 - 0.57 8.7 3.2 0.66 8.4 2.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 EIM88285.1 - 1.3 9.1 4.1 6.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Methyltransf_3 PF01596.12 EIM88286.1 - 2.6e-44 150.7 0.0 3.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIM88286.1 - 1.3e-15 58.0 0.0 2.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM88286.1 - 3.2e-09 36.6 0.0 4.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIM88286.1 - 5e-08 32.9 0.0 8.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88286.1 - 5e-08 32.6 0.0 8.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88286.1 - 2.8e-06 27.8 0.0 4.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIM88286.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EIM88286.1 - 0.001 19.5 0.0 0.0036 17.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM88286.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 EIM88286.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.5 EIM88286.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EIM88286.1 - 0.031 13.8 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 EIM88286.1 - 0.035 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TRM PF02005.11 EIM88286.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Aldo_ket_red PF00248.16 EIM88287.1 - 1.1e-70 237.6 0.0 1.3e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 EIM88288.1 - 3.3e-10 39.4 0.3 3.7e-06 26.4 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88288.1 - 0.0057 16.4 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88288.1 - 0.27 11.2 0.3 3.2 7.8 0.0 2.7 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.24 EIM88290.1 - 7.2e-33 113.8 0.0 9.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM88290.1 - 3.2e-10 39.9 0.0 5.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1469 PF07332.6 EIM88292.1 - 0.23 11.1 5.6 0.59 9.8 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) dsrm PF00035.20 EIM88293.1 - 0.002 18.6 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif SBP_bac_11 PF13531.1 EIM88293.1 - 0.045 13.3 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein RRP7 PF12923.2 EIM88294.1 - 2.9e-31 108.2 4.6 2.9e-31 108.2 3.2 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EIM88294.1 - 5.2e-05 22.7 0.0 0.045 13.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88294.1 - 0.0059 16.5 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Statherin PF03875.8 EIM88295.1 - 2.4 8.1 10.1 3.1 7.7 0.6 3.0 3 0 0 3 3 3 0 Statherin adh_short PF00106.20 EIM88297.1 - 2.8e-21 76.1 0.2 6.7e-20 71.6 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM88297.1 - 3.1e-12 46.7 1.3 5.8e-11 42.6 0.9 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM88297.1 - 2.1e-08 34.0 0.1 4.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.22 EIM88297.1 - 6e-05 23.3 0.5 0.0015 18.8 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 EIM88297.1 - 0.00067 18.6 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EIM88297.1 - 0.0014 18.3 0.5 0.0061 16.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 EIM88297.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus Epimerase PF01370.16 EIM88297.1 - 0.098 12.0 0.1 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 EIM88297.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EIM88297.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1776 PF08643.5 EIM88297.1 - 0.14 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_tran_WecB PF03808.8 EIM88297.1 - 0.15 11.4 0.1 0.47 9.8 0.0 1.9 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family RRM_1 PF00076.17 EIM88298.1 - 5e-32 109.3 0.0 3.8e-16 58.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88298.1 - 5.5e-19 67.9 0.0 1.3e-10 41.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88298.1 - 1.9e-14 53.1 0.0 7.3e-10 38.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM88298.1 - 3.3e-06 26.8 0.0 1.3e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIM88298.1 - 0.00018 21.1 0.0 0.00056 19.6 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RasGAP PF00616.14 EIM88299.1 - 2.9e-31 108.6 0.0 6.2e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIM88299.1 - 4.4e-11 42.8 0.1 1.4e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 EIM88299.1 - 8.3e-06 25.7 0.2 3.3e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal NYD-SP28_assoc PF14775.1 EIM88300.1 - 0.4 10.4 6.8 0.27 10.9 0.2 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Spc7 PF08317.6 EIM88300.1 - 3.2 6.3 30.5 0.26 9.9 1.1 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein ABM PF03992.11 EIM88301.1 - 0.00067 19.6 0.2 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.8 EIM88301.1 - 0.12 12.3 0.2 1.4 8.9 0.1 2.2 1 1 1 2 2 2 0 NIPSNAP zf-C2H2 PF00096.21 EIM88302.1 - 5.7e-16 57.8 49.8 0.0082 16.4 1.4 8.6 7 2 2 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIM88302.1 - 1.6e-12 47.1 48.7 7e-05 22.8 2.5 7.4 7 1 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIM88302.1 - 3.8e-12 45.6 44.6 0.018 15.3 0.4 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.2 EIM88302.1 - 1.6e-11 44.0 36.8 0.0017 18.5 2.1 7.2 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIM88302.1 - 1.2e-07 31.3 43.4 0.043 13.7 0.0 8.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIM88302.1 - 0.0011 19.0 31.6 0.085 12.9 0.5 5.5 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EIM88302.1 - 0.035 14.3 2.4 0.21 11.9 0.3 7.5 6 2 0 6 6 6 0 Zinc-finger double domain zf-4CXXC_R1 PF10497.4 EIM88302.1 - 0.21 11.7 9.3 0.076 13.1 2.3 2.8 2 1 1 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Rad50_zn_hook PF04423.9 EIM88302.1 - 0.32 10.4 4.6 13 5.3 0.4 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif BssC_TutF PF08201.6 EIM88302.1 - 3.1 7.3 8.9 23 4.5 0.1 3.4 3 0 0 3 3 3 0 BssC/TutF protein Arc_trans_TRASH PF08394.5 EIM88302.1 - 5.7 7.1 9.8 0.99 9.6 0.2 3.6 4 0 0 4 4 4 0 Archaeal TRASH domain Isochorismatase PF00857.15 EIM88303.1 - 1.4e-30 106.4 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF2353 PF09789.4 EIM88304.1 - 0.097 11.9 9.1 0.16 11.1 6.3 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.1 EIM88304.1 - 0.12 12.3 10.7 0.26 11.2 7.4 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EIM88304.1 - 0.5 9.9 12.8 1.6 8.2 8.9 1.9 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EIM88304.1 - 1.3 8.1 8.9 0.55 9.4 4.1 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EIM88304.1 - 6.1 6.7 9.2 7.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding B12D PF06522.6 EIM88305.1 - 7.4e-12 44.8 0.4 9.4e-12 44.4 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.16 EIM88306.1 - 1.3e-43 148.8 0.0 1.6e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_20 PF00686.14 EIM88307.1 - 1.2e-30 105.0 0.1 2.7e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 EIM88307.1 - 1.4e-17 64.0 0.0 8.3e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIM88307.1 - 1.1e-09 38.2 0.0 4.3e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Thioredoxin PF00085.15 EIM88308.1 - 0.0006 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pollen_Ole_e_I PF01190.12 EIM88308.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Pollen proteins Ole e I like Cytochrom_B562 PF07361.6 EIM88308.1 - 0.044 14.1 0.1 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 DUF1479 PF07350.7 EIM88309.1 - 8.5e-129 429.6 0.0 9.8e-129 429.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EIM88309.1 - 0.00031 20.8 0.0 0.032 14.2 0.1 2.9 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) OMPdecase PF00215.19 EIM88310.1 - 5.2e-64 215.7 0.3 4e-42 144.1 0.0 2.1 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family TFX_C PF14601.1 EIM88310.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term PIN_4 PF13638.1 EIM88311.1 - 1.1e-19 70.8 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain PIN PF01850.16 EIM88311.1 - 0.11 12.8 0.1 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 PIN domain Gly_transf_sug PF04488.10 EIM88312.1 - 9.6e-20 70.9 0.0 2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4064 PF13273.1 EIM88312.1 - 0.0027 17.7 0.1 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) TcdA_TcdB PF12919.2 EIM88312.1 - 0.013 14.0 1.6 0.19 10.1 0.5 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 EIM88313.1 - 2.2e-30 105.6 22.2 6.8e-29 100.6 12.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88313.1 - 3.4e-06 25.9 6.8 3.8e-06 25.7 4.0 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM88313.1 - 7.5e-05 21.2 9.3 0.012 14.0 1.0 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein Bac_export_2 PF01312.14 EIM88313.1 - 0.0046 15.8 0.1 0.029 13.2 0.0 2.1 2 0 0 2 2 2 1 FlhB HrpN YscU SpaS Family DUF791 PF05631.9 EIM88313.1 - 0.0073 15.0 0.3 0.013 14.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TruD PF01142.13 EIM88314.1 - 2.9e-66 223.6 0.0 4.5e-65 219.7 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) mRNA_triPase PF02940.10 EIM88315.1 - 0.0058 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HNF-1_N PF04814.8 EIM88315.1 - 0.0094 16.0 0.5 0.022 14.8 0.3 1.7 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus DAP3 PF10236.4 EIM88315.1 - 0.032 13.1 0.2 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ribosomal_L6 PF00347.18 EIM88316.1 - 5.1e-27 94.1 1.5 1.4e-13 51.1 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.9 EIM88317.1 - 8.1e-27 93.2 1.4 1.3e-26 92.6 1.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM88317.1 - 5.2e-13 49.0 2.6 5.2e-13 49.0 1.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EIM88317.1 - 8.5e-05 22.0 1.3 0.00016 21.1 0.9 1.4 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.12 EIM88317.1 - 0.00096 17.7 0.3 0.0015 17.1 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TcpE PF12648.2 EIM88317.1 - 0.29 11.3 5.8 0.25 11.5 0.4 2.5 2 0 0 2 2 2 0 TcpE family GTP_EFTU PF00009.22 EIM88318.1 - 2.7e-49 167.1 0.0 4.8e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIM88318.1 - 4.5e-16 58.4 0.1 8.5e-08 31.9 0.0 2.8 3 0 0 3 3 3 2 Elongation factor G C-terminus EFG_II PF14492.1 EIM88318.1 - 7.1e-12 45.0 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIM88318.1 - 2.1e-06 27.7 0.0 8.9e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM88318.1 - 0.0012 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EIM88318.1 - 0.02 14.5 0.1 0.2 11.3 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EIM88318.1 - 0.068 12.3 0.0 0.21 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EIM88318.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin AIG1 PF04548.11 EIM88318.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ADH_N PF08240.7 EIM88319.1 - 4.8e-32 109.9 0.3 8.6e-32 109.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM88319.1 - 9.3e-21 73.7 0.2 1.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM88319.1 - 1.6e-06 29.0 0.0 3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIM88319.1 - 0.0022 17.3 0.0 0.0084 15.5 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1212 PF06738.7 EIM88320.1 - 4.3e-37 127.4 11.8 1.2e-35 122.7 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM88320.1 - 4.7e-12 45.9 7.7 4.7e-12 45.9 5.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Hormone_recep PF00104.25 EIM88320.1 - 0.085 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Meth_synt_2 PF01717.13 EIM88321.1 - 1.2e-139 464.8 0.0 2.7e-135 450.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM88321.1 - 1.9e-125 418.2 0.0 2.4e-112 375.2 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Rsd_AlgQ PF04353.8 EIM88321.1 - 0.081 12.6 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SHOCT PF09851.4 EIM88321.1 - 4.2 6.9 7.4 0.18 11.3 0.5 2.3 2 0 0 2 2 2 0 Short C-terminal domain UPF0183 PF03676.9 EIM88322.1 - 1.4e-44 152.2 0.0 3.8e-44 150.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) HAD_2 PF13419.1 EIM88323.1 - 4.7e-32 111.6 0.1 5.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM88323.1 - 2.2e-08 34.7 0.0 3.3e-06 27.6 0.0 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM88323.1 - 0.0027 17.3 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EIM88323.1 - 0.0029 17.2 0.0 0.023 14.3 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.3 EIM88323.1 - 0.0038 16.2 0.1 2.1 7.2 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2608) Globin PF00042.17 EIM88323.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Globin HAD PF12710.2 EIM88323.1 - 0.027 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L6e PF01159.14 EIM88324.1 - 9.3e-38 128.7 2.7 1.4e-37 128.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIM88324.1 - 3.6e-07 29.9 0.1 3.6e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain ROS_MUCR PF05443.6 EIM88324.1 - 0.031 14.0 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Plus-3 PF03126.13 EIM88324.1 - 0.098 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Plus-3 domain 60KD_IMP PF02096.15 EIM88325.1 - 9.9e-16 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein adh_short PF00106.20 EIM88327.1 - 2.9e-19 69.6 0.0 4.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM88327.1 - 5.9e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM88327.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIM88327.1 - 0.0021 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.18 EIM88327.1 - 0.0042 16.8 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EIM88327.1 - 0.012 15.5 0.4 0.049 13.6 0.2 2.0 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EIM88327.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EIM88327.1 - 0.014 14.9 0.1 0.047 13.2 0.0 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Helicase_RecD PF05127.9 EIM88327.1 - 0.05 13.2 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Helicase ApbA PF02558.11 EIM88327.1 - 0.062 12.7 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.1 EIM88327.1 - 0.063 13.0 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIM88327.1 - 0.067 12.9 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 EIM88327.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus CRCB PF02537.10 EIM88328.1 - 3.6e-33 113.9 15.6 2.4e-20 72.5 4.4 2.4 2 1 0 2 2 2 2 CrcB-like protein HTH_Tnp_4 PF13613.1 EIM88328.1 - 0.068 12.7 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CK_II_beta PF01214.13 EIM88329.1 - 2.1e-77 258.7 0.0 2.8e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nop14 PF04147.7 EIM88329.1 - 0.027 12.3 5.8 0.036 12.0 4.0 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIM88329.1 - 0.08 12.2 8.4 0.11 11.7 5.8 1.1 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 EIM88329.1 - 1.4 8.9 9.2 2.3 8.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_L36e PF01158.13 EIM88330.1 - 5.5e-38 128.8 4.9 6e-38 128.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e KH_1 PF00013.24 EIM88332.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIM88332.1 - 0.0027 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EIM88332.1 - 0.0079 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 KH domain DUF2414 PF10309.4 EIM88334.1 - 3.1e-05 23.5 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 EIM88334.1 - 0.024 15.0 0.4 0.024 15.0 0.3 3.6 3 1 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 DUF410 PF04190.8 EIM88335.1 - 1.5e-28 100.0 0.0 2.4e-28 99.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF410) HSBP1 PF06825.7 EIM88336.1 - 7.6e-17 60.6 1.3 1e-16 60.2 0.9 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 ApoO PF09769.4 EIM88336.1 - 0.014 15.1 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O RRN3 PF05327.6 EIM88336.1 - 0.032 12.3 0.0 0.038 12.1 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4164 PF13747.1 EIM88336.1 - 0.15 12.2 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Epiglycanin_TR PF05647.6 EIM88336.1 - 7.5 6.4 13.7 2.9 7.7 0.8 2.3 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like DUF4166 PF13761.1 EIM88337.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) Terpene_synth_C PF03936.11 EIM88338.1 - 2.3e-21 76.2 0.0 3.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank PF00023.25 EIM88339.1 - 2e-19 68.3 2.4 5.6e-07 29.0 0.2 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EIM88339.1 - 5.8e-18 65.0 0.1 6.1e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM88339.1 - 1.5e-16 60.0 1.2 8.9e-07 28.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM88339.1 - 5.6e-15 55.3 0.1 2e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM88339.1 - 2.6e-14 51.8 1.4 3.6e-05 23.6 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIM88340.1 - 3.8e-17 62.2 0.0 1.7e-11 44.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIM88340.1 - 1.2e-16 59.6 0.7 6.6e-11 41.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIM88340.1 - 1.3e-13 51.0 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM88340.1 - 2.4e-12 46.6 0.0 1.9e-06 27.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM88340.1 - 9.4e-10 37.7 0.0 4.8e-06 26.3 0.0 2.3 3 0 0 3 3 3 2 Ankyrin repeat F-box-like PF12937.2 EIM88343.1 - 9.4e-08 31.6 2.2 1.9e-07 30.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM88343.1 - 0.0011 18.5 5.8 0.15 11.7 0.2 4.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM88343.1 - 0.025 14.3 4.4 1.1 9.0 0.2 4.4 2 1 2 4 4 4 0 Leucine rich repeat ADH_N PF08240.7 EIM88344.1 - 0.0013 18.4 0.3 0.0032 17.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain JmjC PF02373.17 EIM88345.1 - 1.6e-15 57.3 1.5 6.8e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase FTR PF01913.13 EIM88345.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Prok-RING_2 PF14445.1 EIM88345.1 - 1.8 8.5 11.0 0.32 10.9 2.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FYVE PF01363.16 EIM88345.1 - 3.9 7.4 13.8 0.049 13.5 3.7 2.2 2 0 0 2 2 2 0 FYVE zinc finger Response_reg PF00072.19 EIM88346.1 - 8.5e-24 83.7 0.1 4.8e-17 61.9 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.3 EIM88347.1 - 3.4e-16 59.2 1.8 8e-16 58.0 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EIM88347.1 - 1.4e-13 51.5 0.1 1.4e-13 51.5 0.1 3.2 4 1 1 5 5 5 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EIM88347.1 - 2.5e-05 23.7 0.3 8.7e-05 22.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.21 EIM88347.1 - 0.032 14.5 0.3 0.032 14.5 0.2 2.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM88347.1 - 0.12 12.7 1.4 3 8.3 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger RRM_6 PF14259.1 EIM88348.1 - 5e-07 29.5 0.0 1.7e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM88348.1 - 8.7e-05 22.0 0.0 0.016 14.7 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88348.1 - 0.0077 16.0 0.0 0.14 11.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIID-18kDa PF02269.11 EIM88349.1 - 8.9e-27 92.7 0.6 2e-26 91.6 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Zn_clus PF00172.13 EIM88351.1 - 0.001 18.9 5.7 0.0019 18.0 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0029 PF01205.14 EIM88352.1 - 2.8e-26 91.3 0.0 5e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EIM88352.1 - 1.4e-06 28.1 0.1 3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 RWD domain Aldedh PF00171.17 EIM88353.1 - 3.3e-158 526.8 2.4 3.7e-158 526.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CDC14 PF08045.6 EIM88354.1 - 1.3e-38 132.6 0.0 2.5e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Cell division control protein 14, SIN component Cyt-b5 PF00173.23 EIM88355.1 - 8.7e-24 83.1 0.0 1.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Shugoshin_N PF07558.6 EIM88356.1 - 0.035 13.8 1.6 0.059 13.0 0.0 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vac_Fusion PF02346.11 EIM88356.1 - 0.3 10.5 4.2 0.11 11.9 0.7 1.9 2 0 0 2 2 2 0 Chordopoxvirus fusion protein IncA PF04156.9 EIM88356.1 - 0.6 9.6 11.2 0.64 9.5 3.1 2.5 2 0 0 2 2 2 0 IncA protein DUF904 PF06005.7 EIM88356.1 - 2.7 8.3 14.5 1.9 8.8 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Herpes_UL6 PF01763.11 EIM88356.1 - 7.6 4.5 8.6 0.41 8.7 0.4 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF3782 PF12644.2 EIM88356.1 - 9.2 6.1 8.6 0.88 9.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) FlxA PF14282.1 EIM88356.1 - 9.9 6.1 17.3 1.3 8.9 5.0 3.0 2 0 0 2 2 2 0 FlxA-like protein HIG_1_N PF04588.8 EIM88357.1 - 2e-05 24.2 1.9 4e-05 23.2 1.3 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_M50 PF02163.17 EIM88358.1 - 0.019 13.9 0.4 0.07 12.0 0.3 1.8 1 1 0 1 1 1 0 Peptidase family M50 CytochromB561_N PF09786.4 EIM88358.1 - 0.14 10.6 0.6 3.8 5.8 0.2 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal Ofd1_CTDD PF10637.4 EIM88359.1 - 8.9e-83 277.4 0.0 1.1e-78 264.0 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EIM88359.1 - 1.1e-14 54.7 0.1 2.2e-13 50.5 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 EIM88359.1 - 0.036 13.1 10.5 0.07 12.1 7.3 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EIM88359.1 - 2.6 5.8 15.0 3.8 5.3 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family FMN_dh PF01070.13 EIM88360.1 - 2.8e-108 361.9 0.0 3.8e-108 361.5 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIM88360.1 - 3.3e-19 68.4 0.0 7.9e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIM88360.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase IMPDH PF00478.20 EIM88360.1 - 0.012 14.5 0.9 0.049 12.5 0.1 2.2 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIM88360.1 - 0.018 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase NIF PF03031.13 EIM88361.1 - 5.8e-43 146.3 0.0 6.6e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCHC PF00098.18 EIM88362.1 - 1.8 8.6 30.4 0.043 13.7 0.9 4.5 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIM88362.1 - 3.8 7.2 29.0 0.21 11.2 0.4 4.3 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIM88362.1 - 3.9 7.2 31.4 0.82 9.4 1.9 5.0 2 1 3 5 5 5 0 Zinc knuckle MFS_1 PF07690.11 EIM88364.1 - 1.1e-37 129.6 42.8 7.7e-37 126.8 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Snf7 PF03357.16 EIM88365.1 - 7e-37 126.4 19.8 7e-37 126.4 13.7 1.9 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.14 EIM88365.1 - 0.0021 18.4 3.2 0.0021 18.4 2.2 2.8 2 1 1 3 3 3 1 60s Acidic ribosomal protein Macoilin PF09726.4 EIM88365.1 - 1.2 7.2 16.1 1.1 7.4 9.7 1.8 1 1 1 2 2 2 0 Transmembrane protein Terpene_synth_C PF03936.11 EIM88366.1 - 1.2e-12 47.6 0.3 2.8e-12 46.4 0.1 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Mob1_phocein PF03637.12 EIM88367.1 - 6e-73 244.2 0.0 7e-73 244.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.24 EIM88369.1 - 1.6e-41 141.5 0.0 2.9e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM88369.1 - 1.1e-23 82.8 0.0 2.7e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM88369.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HMG_box PF00505.14 EIM88371.1 - 5.5e-12 45.7 0.1 6.9e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM88371.1 - 0.0021 18.3 0.1 0.0025 18.1 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain PLD_C PF12357.3 EIM88371.1 - 0.13 11.8 0.1 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Phospholipase D C terminal Sua5_yciO_yrdC PF01300.13 EIM88372.1 - 3.2e-55 186.1 0.0 6.2e-55 185.2 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EIM88372.1 - 1e-26 93.4 0.0 1.7e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Opy2 PF09463.5 EIM88373.1 - 4.2e-05 23.5 17.5 6.6e-05 22.9 12.1 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 EIM88373.1 - 0.034 13.4 0.1 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CorA PF01544.13 EIM88375.1 - 1.1e-37 129.6 10.1 2.5e-34 118.6 6.1 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein APH PF01636.18 EIM88376.1 - 0.0024 17.6 1.1 0.0063 16.2 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.13 EIM88377.1 - 2.7e-37 128.4 8.2 1.1e-32 113.2 5.6 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SOBP PF15279.1 EIM88377.1 - 0.019 15.3 3.2 0.037 14.4 2.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pyridoxal_deC PF00282.14 EIM88378.1 - 2e-109 365.4 0.0 5.9e-109 363.9 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HTH_8 PF02954.14 EIM88378.1 - 0.075 12.5 0.2 15 5.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family NMT1 PF09084.6 EIM88379.1 - 0.0075 15.8 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 2 NMT1/THI5 like DDE_Tnp_1 PF01609.16 EIM88379.1 - 0.067 12.7 0.2 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain MFS_1 PF07690.11 EIM88380.1 - 4.6e-24 84.7 32.3 9.5e-24 83.7 22.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88380.1 - 1.4e-09 37.0 9.2 1.4e-09 37.0 6.4 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter Con-6 PF10346.4 EIM88381.1 - 4.2e-14 51.6 0.2 6.3e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Conidiation protein 6 Ribosomal_S10 PF00338.17 EIM88381.1 - 0.3 10.9 1.4 0.53 10.1 1.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Sod_Fe_C PF02777.13 EIM88383.1 - 8.6e-07 28.7 0.1 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.11 EIM88384.1 - 5.8e-47 158.4 3.7 6.9e-47 158.1 2.6 1.0 1 0 0 1 1 1 1 DAD family DUF1748 PF08520.5 EIM88385.1 - 5.9e-26 89.9 0.0 6.5e-26 89.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coat_F PF07875.7 EIM88385.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Coat F domain F-box-like PF12937.2 EIM88388.1 - 8.1e-06 25.4 1.2 2.2e-05 24.0 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88388.1 - 9e-06 25.2 0.7 2e-05 24.1 0.5 1.7 1 0 0 1 1 1 1 F-box domain Proteasome PF00227.21 EIM88389.1 - 1.9e-54 183.8 0.0 2.3e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM88389.1 - 4e-13 48.4 0.0 4e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AAA_6 PF12774.2 EIM88390.1 - 0.5 9.8 0.0 1.5 8.2 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 Cyt-b5 PF00173.23 EIM88392.1 - 6.3e-11 41.9 0.1 1.7e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.14 EIM88393.1 - 7.4e-34 116.3 0.1 3.9e-33 114.0 0.0 2.3 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EIM88393.1 - 1.6e-13 50.1 0.0 1.4e-07 31.1 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_A4 PF01828.12 EIM88395.1 - 4.7e-84 280.6 15.0 5.6e-84 280.3 10.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family ORC6 PF05460.8 EIM88396.1 - 0.0054 15.8 0.1 0.0065 15.6 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Bacillus_HBL PF05791.6 EIM88398.1 - 0.021 14.2 2.0 0.034 13.5 0.2 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Nucleo_P87 PF07267.6 EIM88398.1 - 0.045 12.4 8.7 0.053 12.2 6.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BicD PF09730.4 EIM88398.1 - 0.1 10.9 8.6 0.045 12.1 4.0 1.7 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D PRA-PH PF01503.12 EIM88398.1 - 0.28 11.4 1.3 0.59 10.4 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase TMF_DNA_bd PF12329.3 EIM88398.1 - 1.2 8.9 7.2 0.78 9.5 0.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIM88398.1 - 2 7.9 7.3 1.5 8.3 0.9 2.3 2 0 0 2 2 2 0 IncA protein Ank_4 PF13637.1 EIM88401.1 - 2.3e-24 85.3 3.5 5.2e-12 45.9 0.1 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM88401.1 - 6.4e-23 80.9 0.1 1.2e-15 57.6 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM88401.1 - 1.3e-21 75.2 0.4 3e-08 33.0 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIM88401.1 - 5.1e-19 67.8 2.3 1.2e-09 38.0 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM88401.1 - 1.8e-15 55.5 0.2 8.6e-05 22.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat MFS_2 PF13347.1 EIM88402.1 - 2.1e-11 42.9 9.4 2.1e-11 42.9 6.5 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 EIM88402.1 - 3.7e-11 42.3 26.3 1.7e-09 36.8 19.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM88402.1 - 0.72 9.6 8.2 1.2 8.9 0.0 4.0 3 1 0 3 3 3 0 MFS_1 like family ATP_bind_4 PF01902.12 EIM88403.1 - 3.5e-40 137.6 0.0 7.3e-38 130.1 0.0 2.2 1 1 0 1 1 1 1 ATP-binding region B3_4 PF03483.12 EIM88404.1 - 4.2e-26 91.4 0.2 8e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EIM88404.1 - 5.3e-17 61.3 0.0 1.4e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EIM88404.1 - 0.005 16.0 0.0 0.066 12.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF2424 PF10340.4 EIM88405.1 - 1.1e-18 67.0 0.0 1.6e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EIM88405.1 - 5.4e-17 62.0 0.0 7.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM88405.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family SNARE_assoc PF09335.6 EIM88407.1 - 6.9e-18 65.0 5.7 6.9e-18 65.0 4.0 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein tRNA-synt_2d PF01409.15 EIM88408.1 - 4.7e-84 281.4 0.0 5.2e-55 186.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EIM88408.1 - 6.4e-05 21.8 0.4 0.0031 16.3 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EIM88408.1 - 0.00054 19.5 0.1 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4556 PF15094.1 EIM88408.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Acetyltransf_1 PF00583.19 EIM88409.1 - 1.4e-11 44.2 0.1 2.8e-11 43.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EIM88409.1 - 7.9e-06 26.0 0.0 0.0019 18.3 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM88409.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIM88409.1 - 0.00025 21.1 0.1 0.00089 19.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM88409.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2370 PF10176.4 EIM88412.1 - 4e-67 225.9 0.1 8e-67 224.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Abhydrolase_3 PF07859.8 EIM88413.1 - 2.2e-20 73.1 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM88413.1 - 4.2e-15 55.2 0.0 6.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIM88413.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIM88413.1 - 0.049 13.0 0.0 0.14 11.5 0.0 1.8 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PX PF00787.19 EIM88414.1 - 5.8e-26 90.5 0.0 7.3e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 EIM88416.1 - 1.6e-65 216.8 2.2 1.8e-22 78.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EIM88416.1 - 1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIM88416.1 - 4.8e-05 22.3 0.0 0.0025 16.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIM88416.1 - 0.00026 20.5 0.0 0.0098 15.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EIM88416.1 - 0.0067 15.7 0.7 0.036 13.4 0.0 2.3 2 0 0 2 2 2 1 EF hand DivIC PF04977.10 EIM88417.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator Prefoldin_2 PF01920.15 EIM88417.1 - 0.034 13.9 0.2 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit AKNA PF12443.3 EIM88417.1 - 0.061 13.3 0.5 0.16 12.0 0.3 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF3740 PF12548.3 EIM88417.1 - 0.08 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Sulfatase protein PEP-utilisers_N PF05524.8 EIM88417.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TFIIF_alpha PF05793.7 EIM88419.1 - 1.7e-18 66.3 45.8 6.4e-09 34.7 26.8 4.1 2 1 1 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTB PF00651.26 EIM88420.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HLH PF00010.21 EIM88421.1 - 2.6e-07 30.2 0.6 6.6e-07 28.9 0.4 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.24 EIM88422.1 - 4.2e-05 23.7 0.1 0.0041 17.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM88422.1 - 0.00092 20.0 0.0 0.0087 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM88422.1 - 0.0041 17.1 0.8 0.013 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 EIM88422.1 - 0.018 13.7 0.0 0.28 9.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EIM88422.1 - 0.033 14.0 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIM88422.1 - 0.045 12.4 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Med20 PF08612.6 EIM88423.1 - 4.8e-08 32.4 0.0 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Mak16 PF04874.9 EIM88423.1 - 0.04 14.0 2.1 0.061 13.4 1.5 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region Pkinase PF00069.20 EIM88425.1 - 5.9e-64 215.7 0.2 1.2e-42 145.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88425.1 - 8.7e-28 97.0 0.1 1.3e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM88425.1 - 2.1e-05 23.6 0.2 7.2e-05 21.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EIM88425.1 - 0.00023 21.6 0.2 0.00056 20.3 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EIM88425.1 - 0.00054 19.0 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM88425.1 - 0.0046 16.7 0.3 0.053 13.2 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM88425.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EIM88425.1 - 0.028 13.2 0.1 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EIM88425.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3818 PF12825.2 EIM88426.1 - 1.8e-108 362.2 0.0 2.3e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EIM88426.1 - 4.6e-26 91.0 0.3 1.5e-25 89.4 0.2 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EIM88426.1 - 4.7e-10 39.2 0.6 2e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 PX domain Nop14 PF04147.7 EIM88426.1 - 0.022 12.7 13.6 0.045 11.6 9.4 1.4 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 EIM88426.1 - 0.046 13.3 18.1 0.0094 15.5 7.6 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Sigma70_ner PF04546.8 EIM88426.1 - 0.14 11.7 12.9 0.47 10.0 8.9 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EIM88426.1 - 5 6.6 16.4 5.3 6.5 9.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF1682 PF07946.9 EIM88428.1 - 4.7e-67 226.1 0.0 5.8e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RNase_H2-Ydr279 PF09468.5 EIM88428.1 - 0.094 11.9 5.9 0.13 11.4 4.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Cgr1 PF03879.9 EIM88428.1 - 3.7 7.7 26.0 6.5 6.9 18.0 1.3 1 0 0 1 1 1 0 Cgr1 family E2_bind PF08825.5 EIM88429.1 - 0.059 13.1 0.2 0.083 12.6 0.1 1.4 1 1 0 1 1 1 0 E2 binding domain 2-oxoacid_dh PF00198.18 EIM88430.1 - 0.04 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) LON PF02190.11 EIM88431.1 - 2.5e-21 76.3 0.0 5.9e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EIM88431.1 - 4.7e-10 38.9 5.0 9.9e-10 37.9 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM88431.1 - 2.9e-09 36.6 11.6 6e-09 35.5 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM88431.1 - 4.8e-09 36.1 10.7 4.8e-09 36.1 7.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM88431.1 - 9.4e-09 34.7 11.5 2.1e-08 33.7 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM88431.1 - 2.8e-08 33.3 11.1 5.3e-08 32.4 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM88431.1 - 6.7e-06 25.8 11.8 1.6e-05 24.6 8.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM88431.1 - 2.9e-05 23.6 4.7 3.9e-05 23.2 2.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 EIM88431.1 - 0.0044 16.4 5.2 0.01 15.3 3.6 1.6 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_6 PF14835.1 EIM88431.1 - 0.0047 16.6 1.7 0.013 15.2 1.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EIM88431.1 - 0.0054 16.8 6.6 0.012 15.6 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EIM88431.1 - 0.015 14.8 7.3 0.028 13.9 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EIM88431.1 - 0.022 14.5 2.9 0.046 13.5 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EIM88431.1 - 0.47 10.3 5.7 1.2 9.0 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) G6PD_C PF02781.11 EIM88432.1 - 2.2e-122 407.5 0.0 2.9e-122 407.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIM88432.1 - 9.7e-63 211.7 0.1 1.4e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EIM88432.1 - 0.026 15.0 0.0 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 EIM88433.1 - 3.3e-38 130.2 0.1 4e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.1 EIM88433.1 - 0.078 12.5 0.2 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family E McrBC PF10117.4 EIM88433.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component DUF2842 PF11003.3 EIM88435.1 - 0.23 11.3 3.4 1.3 8.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) CbiQ PF02361.11 EIM88435.1 - 4 6.9 12.4 2.3 7.7 4.9 2.1 1 1 1 2 2 2 0 Cobalt transport protein RCR PF12273.3 EIM88436.1 - 0.00078 20.0 0.9 0.00078 20.0 0.6 2.4 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Lig_chan PF00060.21 EIM88436.1 - 3.3 7.4 4.9 19 4.9 0.1 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Metallophos PF00149.23 EIM88438.1 - 4.4e-13 49.0 0.6 4.4e-13 49.0 0.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Di19_C PF14571.1 EIM88438.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal RFX_DNA_binding PF02257.10 EIM88439.1 - 1.3e-25 89.3 0.0 2.9e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Ribosomal_L7Ae PF01248.21 EIM88440.1 - 2.1e-23 81.6 0.2 2.1e-23 81.6 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CRA PF06589.6 EIM88440.1 - 0.29 10.4 3.1 0.57 9.4 2.2 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF3069 PF11269.3 EIM88440.1 - 2.6 8.1 5.6 1.2 9.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Cupin_8 PF13621.1 EIM88441.1 - 9.3e-50 169.4 0.0 1.4e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIM88441.1 - 0.0027 17.9 0.3 0.07 13.3 0.0 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EIM88441.1 - 0.021 14.3 0.5 0.24 10.9 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.7 EIM88441.1 - 0.057 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein ORC4_C PF14629.1 EIM88443.1 - 6.2e-25 87.7 0.0 9.4e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EIM88443.1 - 2e-20 73.5 0.1 4.7e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIM88443.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EIM88443.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIM88443.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EIM88443.1 - 0.016 15.4 0.0 0.096 12.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM88443.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.4 EIM88443.1 - 0.029 12.8 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_19 PF13245.1 EIM88443.1 - 0.035 13.8 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EIM88443.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EIM88443.1 - 0.074 12.5 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 EIM88443.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3759 PF12585.3 EIM88444.1 - 1.6e-39 133.6 6.3 1.9e-39 133.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Duffy_binding PF05424.6 EIM88444.1 - 0.055 13.2 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Duffy binding domain DUF1212 PF06738.7 EIM88445.1 - 2.2e-37 128.3 0.2 2.2e-37 128.3 0.2 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM88445.1 - 1.6e-11 44.2 9.4 1.6e-11 44.2 6.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) DUF829 PF05705.9 EIM88446.1 - 1.5e-31 109.9 0.0 2e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EIM88446.1 - 1.7e-06 28.1 1.1 2.1e-06 27.7 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM88446.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3336 PF11815.3 EIM88447.1 - 4.6e-40 136.4 4.0 6.9e-40 135.8 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIM88447.1 - 9.1e-20 71.4 0.1 1.9e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.7 EIM88447.1 - 0.1 12.4 1.3 0.23 11.3 0.9 1.6 1 0 0 1 1 1 0 TadE-like protein DUF468 PF04318.7 EIM88448.1 - 0.4 11.2 2.3 14 6.3 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF468) PCI PF01399.22 EIM88450.1 - 1.5e-10 41.2 0.0 4.5e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EIM88450.1 - 0.021 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 MarR_2 PF12802.2 EIM88450.1 - 0.022 14.4 0.2 6 6.6 0.1 3.2 4 0 0 4 4 4 0 MarR family TPR_12 PF13424.1 EIM88450.1 - 0.1 12.5 1.9 0.47 10.4 0.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat FeoC PF09012.5 EIM88450.1 - 0.11 12.2 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator Pkinase PF00069.20 EIM88451.1 - 1.9e-74 250.0 0.0 2.4e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88451.1 - 1.6e-37 129.0 0.1 4.3e-37 127.6 0.0 1.7 2 1 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM88451.1 - 4.6e-08 32.3 0.0 1.2e-07 31.0 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EIM88451.1 - 0.05 12.6 0.1 0.16 10.9 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EIM88452.1 - 1.1e-24 85.3 5.7 9.7e-11 41.1 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Asp PF00026.18 EIM88453.1 - 6.5e-110 367.3 0.3 7.6e-110 367.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM88453.1 - 1.2e-10 41.6 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM88453.1 - 3.8e-06 26.5 0.0 9.4e-05 22.0 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIM88453.1 - 2e-05 24.9 0.1 0.051 14.0 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Bromodomain PF00439.20 EIM88454.1 - 1.8e-22 79.0 0.2 3.3e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain VID27 PF08553.5 EIM88455.1 - 1.8e-236 787.1 0.0 2.2e-236 786.9 0.0 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein RTA1 PF04479.8 EIM88456.1 - 2e-38 132.1 3.9 3.4e-38 131.3 2.7 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4231 PF14015.1 EIM88456.1 - 0.0045 16.9 1.5 0.016 15.1 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4231) DUF202 PF02656.10 EIM88456.1 - 5.1 7.3 12.1 0.58 10.4 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF202) BTB_2 PF02214.17 EIM88457.1 - 0.035 14.3 0.2 0.15 12.2 0.0 2.1 3 0 0 3 3 3 0 BTB/POZ domain Zip PF02535.17 EIM88457.1 - 0.51 9.2 5.9 0.19 10.6 1.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Rpr2 PF04032.11 EIM88458.1 - 0.015 15.1 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 EIM88458.1 - 0.075 12.2 1.9 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.7 EIM88458.1 - 0.14 11.5 3.5 0.39 10.1 0.2 2.3 2 0 0 2 2 2 0 HypF finger DUF605 PF04652.11 EIM88458.1 - 2 7.7 20.8 2.4 7.4 14.4 1.2 1 0 0 1 1 1 0 Vta1 like PRCC PF10253.4 EIM88458.1 - 6.8 7.3 7.4 16 6.1 5.1 1.7 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RNB PF00773.14 EIM88459.1 - 3.1e-97 325.7 0.1 5.9e-97 324.8 0.0 1.5 1 0 0 1 1 1 1 RNB domain Iso_dh PF00180.15 EIM88460.1 - 9.3e-99 330.6 0.0 1.1e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.13 EIM88461.1 - 1.2e-17 63.7 0.0 2.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM88461.1 - 1.2e-05 25.0 10.0 2.1e-05 24.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L18p PF00861.17 EIM88462.1 - 1.2e-42 144.8 0.0 2.1e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIM88462.1 - 5.3e-33 113.4 4.2 5.3e-33 113.4 2.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MtrA PF04208.9 EIM88462.1 - 0.025 14.0 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A RRM_1 PF00076.17 EIM88463.1 - 1.4e-15 56.6 0.0 2.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88463.1 - 8.7e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88463.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WH2 PF02205.15 EIM88465.1 - 2.8e-05 23.5 2.9 8.1e-05 22.0 0.8 2.5 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.15 EIM88466.1 - 2.7e-58 194.1 0.1 1.5e-30 104.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EIM88466.1 - 3.7e-43 147.4 0.1 3.8e-32 111.5 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM88466.1 - 7e-10 38.9 0.3 0.0011 19.0 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EIM88466.1 - 2.4e-09 37.1 0.1 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIM88466.1 - 2.4e-09 37.3 2.0 0.0041 17.2 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 EIM88466.1 - 2.2e-07 30.5 1.1 0.051 13.1 0.1 3.3 3 0 0 3 3 3 3 Redoxin AhpC-TSA PF00578.16 EIM88466.1 - 3.2e-07 30.0 0.4 0.0029 17.2 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EIM88466.1 - 3.8e-06 25.9 1.0 4.9e-06 25.5 0.2 1.5 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_4 PF13462.1 EIM88466.1 - 0.0079 16.2 0.2 2.6 8.0 0.1 2.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EIM88466.1 - 0.031 14.0 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain Scm3 PF10384.4 EIM88466.1 - 0.15 11.5 0.1 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Centromere protein Scm3 Glutaredoxin PF00462.19 EIM88466.1 - 0.21 11.6 0.8 5.5 7.0 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin TCTP PF00838.12 EIM88467.1 - 6e-72 241.0 1.3 6.7e-72 240.8 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF3526 PF12040.3 EIM88467.1 - 0.037 14.1 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) UTP15_C PF09384.5 EIM88468.1 - 6.4e-48 162.1 0.0 1.1e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EIM88468.1 - 3.5e-33 112.2 2.5 3e-07 30.0 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIM88468.1 - 8.5e-07 27.5 0.3 0.00015 20.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIM88468.1 - 0.036 14.3 0.7 5.7 7.3 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain CAF1C_H4-bd PF12265.3 EIM88468.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EIM88468.1 - 0.19 11.3 0.0 1.1 8.8 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CTNNBL PF08216.6 EIM88469.1 - 3.3e-30 103.8 0.2 1.2e-29 102.0 0.0 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear V-ATPase_H_N PF03224.9 EIM88469.1 - 0.14 11.2 2.3 1.6 7.7 0.3 2.7 2 1 0 2 2 2 0 V-ATPase subunit H Acetyltransf_3 PF13302.1 EIM88471.1 - 6.5e-13 49.0 0.1 7.9e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM88471.1 - 1.1e-11 44.6 0.1 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIM88471.1 - 3.8e-11 43.1 0.1 4e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM88471.1 - 2.6e-05 24.2 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM88471.1 - 0.057 13.5 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_18 PF00704.23 EIM88472.1 - 2e-55 188.6 0.4 8.8e-55 186.5 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TRAM_LAG1_CLN8 PF03798.11 EIM88473.1 - 2.3e-34 118.7 24.6 2.3e-34 118.7 17.1 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIM88473.1 - 1.2e-12 47.1 0.4 3.8e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein Patched PF02460.13 EIM88474.1 - 1.3e-68 231.7 8.9 3.8e-41 140.9 0.1 3.1 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EIM88474.1 - 1.5e-43 147.9 22.6 3.7e-25 88.1 0.1 3.8 4 0 0 4 4 4 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EIM88474.1 - 7.1e-05 20.4 6.8 7.1e-05 20.4 4.7 1.8 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Cyclin PF08613.6 EIM88475.1 - 1.4e-07 31.9 0.0 2.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Amidohydro_2 PF04909.9 EIM88476.1 - 2.6e-10 40.3 0.1 4.1e-10 39.6 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIM88476.1 - 2.6e-09 37.4 0.2 3.3e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FlaC_arch PF05377.6 EIM88476.1 - 0.11 12.4 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Kinesin PF00225.18 EIM88477.1 - 2.1e-106 355.4 0.0 3.1e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Band_7 PF01145.20 EIM88477.1 - 0.0062 16.4 0.1 5.3 6.9 1.9 2.5 1 1 1 2 2 2 2 SPFH domain / Band 7 family TPR_MLP1_2 PF07926.7 EIM88477.1 - 3.6 7.3 9.6 49 3.6 6.7 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein EMP24_GP25L PF01105.19 EIM88478.1 - 5.5e-51 172.8 0.2 6.4e-51 172.6 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4227 PF14004.1 EIM88478.1 - 0.73 9.7 2.7 0.74 9.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) AAA_2 PF07724.9 EIM88479.1 - 5.3e-37 127.3 0.0 8.5e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIM88479.1 - 3.5e-15 56.3 0.0 8.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIM88479.1 - 4.9e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.16 EIM88479.1 - 2.9e-06 26.5 0.1 0.0033 16.6 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIM88479.1 - 8.5e-06 25.5 0.0 2.5e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EIM88479.1 - 6.9e-05 22.3 0.0 0.0024 17.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EIM88479.1 - 0.0002 21.4 0.1 0.0044 17.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM88479.1 - 0.00031 21.5 0.1 0.0016 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM88479.1 - 0.00051 20.0 0.2 0.0012 18.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 EIM88479.1 - 0.0013 17.5 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_3 PF07726.6 EIM88479.1 - 0.0027 17.2 0.0 0.0088 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIM88479.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIM88479.1 - 0.0036 17.1 1.2 0.013 15.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EIM88479.1 - 0.0057 16.2 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM88479.1 - 0.0077 16.5 0.2 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIM88479.1 - 0.0077 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EIM88479.1 - 0.0083 16.1 0.0 0.027 14.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 EIM88479.1 - 0.0097 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EIM88479.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EIM88479.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RuvB_N PF05496.7 EIM88479.1 - 0.022 13.7 0.1 0.23 10.4 0.0 2.2 2 1 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EIM88479.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EIM88479.1 - 0.023 14.5 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EIM88479.1 - 0.026 13.2 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DEAD PF00270.24 EIM88479.1 - 0.028 13.9 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.1 EIM88479.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EIM88479.1 - 0.052 12.9 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.11 EIM88479.1 - 0.067 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EIM88479.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EIM88479.1 - 0.12 12.1 0.2 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EIM88479.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EIM88479.1 - 0.14 11.0 1.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 EIM88479.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase UPF0079 PF02367.12 EIM88479.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Cactin_mid PF10312.4 EIM88480.1 - 3.6e-62 209.0 4.9 3.6e-62 209.0 3.4 2.2 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EIM88480.1 - 5.2e-58 194.0 6.0 1e-57 193.1 4.2 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein CytochromB561_N PF09786.4 EIM88481.1 - 0.11 10.9 9.5 0.23 9.8 6.6 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal JAB PF01398.16 EIM88482.1 - 6.9e-35 119.2 0.2 1.2e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIM88482.1 - 5.2e-30 103.8 3.1 1.2e-29 102.7 2.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EIM88482.1 - 9.7e-09 34.7 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EIM88482.1 - 0.037 13.5 1.5 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Exotox-A_target PF09102.5 EIM88482.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Exotoxin A, targeting Ribosomal_S18 PF01084.15 EIM88483.1 - 5.8e-14 51.6 0.1 7.3e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 EIM88484.1 - 3.8e-63 213.0 0.0 4.8e-41 140.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88484.1 - 9.9e-28 96.9 0.0 1.4e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIM88484.1 - 2.3e-13 50.1 0.0 4.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EIM88484.1 - 7.4e-07 28.4 0.1 0.00023 20.2 0.0 2.4 1 1 0 2 2 2 2 Kinase-like PAS_9 PF13426.1 EIM88484.1 - 0.0015 18.8 0.0 0.0044 17.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EIM88484.1 - 0.025 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIM88484.1 - 0.043 12.6 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EIM88484.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Suc_Fer-like PF06999.7 EIM88487.1 - 4.5e-35 121.7 0.0 6.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.20 EIM88488.1 - 1.2e-67 227.8 0.0 1.5e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88488.1 - 2.8e-29 101.9 0.0 4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIM88488.1 - 2.4e-15 56.7 0.0 1.4e-14 54.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIM88488.1 - 3.6e-08 32.7 0.0 1.9e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like C2 PF00168.25 EIM88488.1 - 1.8e-06 27.7 0.4 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EIM88488.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM88488.1 - 0.015 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIM88488.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1935 PF09149.5 EIM88489.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Flavi_NS2B PF01002.14 EIM88489.1 - 0.31 10.6 2.2 0.48 10.0 0.7 1.9 2 1 0 2 2 2 0 Flavivirus non-structural protein NS2B Fork_head PF00250.13 EIM88490.1 - 1.2e-29 102.2 0.1 2.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Fork head domain CIAPIN1 PF05093.8 EIM88491.1 - 1.8e-29 101.7 5.0 3.5e-29 100.8 3.5 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Med18 PF09637.5 EIM88492.1 - 5.4e-10 39.2 0.0 1.3e-07 31.4 0.0 2.0 1 1 1 2 2 2 2 Med18 protein Cyclin PF08613.6 EIM88493.1 - 1.5e-05 25.4 0.1 3.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 EIM88494.1 - 5.9e-48 162.1 0.0 1.4e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EIM88494.1 - 2.2e-45 153.8 0.5 5.1e-45 152.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EIM88494.1 - 3.2e-41 138.7 0.2 3.5e-28 96.9 0.1 3.4 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIM88494.1 - 4.4e-23 80.3 0.7 2.3e-18 65.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site DUF3402 PF11882.3 EIM88495.1 - 9.3e-126 420.1 0.0 1.4e-125 419.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EIM88495.1 - 3.6e-40 137.6 0.0 6.8e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Lipase_chap PF03280.9 EIM88496.1 - 0.048 13.1 3.8 0.091 12.2 2.6 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Z1 PF10593.4 EIM88497.1 - 0.018 14.2 0.8 0.023 13.8 0.5 1.1 1 0 0 1 1 1 0 Z1 domain Rhabdo_glycop PF00974.13 EIM88497.1 - 0.14 10.3 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein APG6 PF04111.7 EIM88497.1 - 0.82 8.6 7.1 1 8.3 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-H PF05837.7 EIM88497.1 - 2.3 8.4 7.7 4.3 7.5 5.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) GAS2 PF02187.12 EIM88498.1 - 5.2e-09 35.7 0.1 1.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Gp58 PF07902.6 EIM88498.1 - 0.37 8.9 8.0 0.092 10.9 0.1 2.5 2 0 0 2 2 2 0 gp58-like protein Bestrophin PF01062.16 EIM88499.1 - 1.3e-49 168.7 0.0 9.7e-30 103.5 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DIRP PF06584.8 EIM88500.1 - 0.0055 16.5 0.2 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 DIRP DZR PF12773.2 EIM88500.1 - 0.014 15.1 1.2 0.86 9.4 0.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 EIM88500.1 - 0.059 13.4 0.9 0.22 11.6 0.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger DCR PF14047.1 EIM88500.1 - 0.064 13.5 1.5 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 Dppa2/4 conserved region zf-RING_2 PF13639.1 EIM88500.1 - 0.079 12.8 0.7 0.18 11.6 0.3 1.9 1 1 0 1 1 1 0 Ring finger domain Imm3 PF14425.1 EIM88500.1 - 0.11 12.4 1.1 0.17 11.8 0.7 1.2 1 0 0 1 1 1 0 Immunity protein Imm3 zf-RING_5 PF14634.1 EIM88500.1 - 0.22 11.2 5.3 0.12 12.1 1.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM88500.1 - 0.25 11.4 2.9 0.22 11.5 0.4 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 EIM88500.1 - 0.69 10.3 5.9 0.56 10.6 2.0 2.0 1 1 1 2 2 2 0 SlyX zf-C3HC4_3 PF13920.1 EIM88500.1 - 1.3 8.7 5.1 0.56 9.9 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aconitase PF00330.15 EIM88502.1 - 3e-180 599.6 0.0 3.5e-180 599.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIM88502.1 - 4.3e-42 143.3 0.0 6.9e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.12 EIM88503.1 - 3.5e-21 74.7 12.6 4.5e-21 74.4 8.7 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Endostatin PF06482.6 EIM88503.1 - 0.03 13.7 0.2 0.032 13.6 0.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Tau95 PF09734.4 EIM88504.1 - 1.4e-63 215.0 0.0 2.2e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit ComZ PF10815.3 EIM88505.1 - 0.033 13.9 0.2 0.96 9.2 0.1 2.2 2 0 0 2 2 2 0 ComZ Ins_allergen_rp PF06757.8 EIM88505.1 - 0.081 12.4 0.1 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Sld5 PF05916.6 EIM88506.1 - 0.00035 20.8 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein UPF0160 PF03690.8 EIM88506.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Pkr1 PF08636.5 EIM88507.1 - 6.8e-05 22.8 2.6 6.8e-05 22.8 1.8 1.7 2 0 0 2 2 2 1 ER protein Pkr1 DUF3722 PF12519.3 EIM88508.1 - 4e-95 317.9 0.0 5.4e-95 317.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EIM88508.1 - 0.0015 17.9 0.0 0.12 11.6 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic porin Diphthamide_syn PF01866.12 EIM88509.1 - 1.2e-86 290.7 0.0 3.8e-49 167.5 0.0 4.1 2 1 0 2 2 2 2 Putative diphthamide synthesis protein DUF1378 PF07125.6 EIM88509.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Fungal_trans PF04082.13 EIM88510.1 - 1.8e-27 95.8 0.4 3.8e-27 94.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MtrB PF05440.7 EIM88510.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Sugar_tr PF00083.19 EIM88513.1 - 4.3e-111 371.6 19.7 5e-111 371.4 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM88513.1 - 1.9e-25 89.3 52.2 2.8e-24 85.5 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATE_C PF04377.10 EIM88514.1 - 2.2e-40 137.6 0.1 3.8e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EIM88514.1 - 4.7e-24 84.0 4.6 1.1e-23 82.7 2.4 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus WD40 PF00400.27 EIM88515.1 - 9.7e-05 22.1 0.1 0.075 12.9 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat EF-hand_1 PF00036.27 EIM88517.1 - 1.2e-24 83.7 9.6 7.8e-08 31.0 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EIM88517.1 - 1.2e-24 86.1 5.9 8.6e-15 54.6 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIM88517.1 - 2.6e-19 67.3 5.4 5.9e-06 25.7 0.2 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 EIM88517.1 - 3.7e-13 48.8 7.4 2.8e-06 26.8 0.6 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EIM88517.1 - 7.8e-13 47.1 9.5 0.00041 19.5 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 EIM88517.1 - 2e-07 30.7 5.1 0.038 13.7 0.0 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIM88517.1 - 6.2e-05 23.0 2.2 0.017 15.1 0.1 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EIM88517.1 - 0.00076 19.3 3.5 1.3 9.0 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain S10_plectin PF03501.10 EIM88517.1 - 0.005 16.6 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 EIM88517.1 - 0.0061 16.2 1.3 11 5.7 0.0 4.2 5 0 0 5 5 5 1 EF hand EF-hand_2 PF09068.6 EIM88517.1 - 0.054 13.5 0.1 11 6.1 0.0 2.9 3 1 0 3 3 3 0 EF hand DUF106 PF01956.11 EIM88518.1 - 1.6e-41 141.6 0.0 2e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Sec63 PF02889.11 EIM88519.1 - 3.2e-87 292.6 0.0 4.4e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIM88519.1 - 1.4e-39 135.2 0.8 1.4e-24 86.5 0.5 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIM88519.1 - 2.3e-10 40.6 0.1 9.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIM88519.1 - 1e-06 28.5 0.0 8.5e-06 25.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM88519.1 - 5.5e-06 25.3 0.1 0.0031 16.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 EIM88519.1 - 9.4e-05 22.5 0.1 1.1 9.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA PF00004.24 EIM88519.1 - 0.00021 21.5 0.1 0.34 11.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EIM88519.1 - 0.0028 17.1 0.0 0.78 9.1 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EIM88519.1 - 0.035 13.5 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Aminotran_1_2 PF00155.16 EIM88520.1 - 1.6e-65 221.4 0.0 1.8e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIM88520.1 - 1.3e-08 34.3 0.0 1.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIM88520.1 - 2.3e-06 26.1 0.0 3.9e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIM88520.1 - 7.8e-06 25.2 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIM88520.1 - 0.0058 15.4 0.0 0.09 11.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V F-box-like PF12937.2 EIM88521.1 - 0.0022 17.6 0.1 0.0065 16.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like NAD_binding_6 PF08030.7 EIM88523.1 - 2.3e-19 69.8 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM88523.1 - 2.5e-15 56.2 0.0 4.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIM88523.1 - 5.6e-12 45.8 11.7 5.6e-12 45.8 8.1 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FYVE PF01363.16 EIM88524.1 - 1.4e-17 63.3 10.5 1.4e-17 63.3 7.3 3.0 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.1 EIM88524.1 - 3e-11 42.9 4.2 3e-11 42.9 2.9 3.9 3 1 1 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EIM88524.1 - 3.6e-05 23.7 0.7 3.6e-05 23.7 0.5 3.3 4 0 0 4 4 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM88524.1 - 8.6e-05 22.4 4.4 8.6e-05 22.4 3.0 4.6 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIM88524.1 - 0.002 18.0 2.5 0.002 18.0 1.7 2.9 4 1 0 4 4 3 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EIM88524.1 - 0.0064 16.1 2.3 0.0064 16.1 1.6 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM88524.1 - 0.011 15.4 3.1 0.011 15.4 2.1 4.1 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EIM88524.1 - 0.011 15.6 8.4 0.011 15.6 5.9 2.8 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 EIM88524.1 - 2.2 8.0 31.9 0.072 12.8 2.7 4.0 3 1 1 4 4 4 0 zinc-RING finger domain SprT-like PF10263.4 EIM88524.1 - 5.5 6.6 7.7 19 4.9 2.8 2.3 1 1 0 2 2 2 0 SprT-like family DZR PF12773.2 EIM88524.1 - 5.6 6.8 16.5 17 5.2 1.2 3.9 2 1 1 3 3 3 0 Double zinc ribbon Baculo_PP31 PF05311.6 EIM88525.1 - 0.0099 15.1 0.9 0.023 13.9 0.6 1.5 1 1 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) Prothymosin PF03247.9 EIM88525.1 - 0.67 10.1 10.8 1.4 9.1 7.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family PI31_Prot_N PF11566.3 EIM88526.1 - 7.7e-25 87.2 0.0 1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EIM88526.1 - 2.2e-08 34.5 18.4 2.2e-08 34.5 12.7 3.4 2 1 1 3 3 3 1 PI31 proteasome regulator DEAD PF00270.24 EIM88527.1 - 1.5e-46 157.9 0.0 1.5e-45 154.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM88527.1 - 8.2e-24 83.2 0.0 1.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM88527.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EIM88527.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EIM88528.1 - 3.9e-41 140.9 42.6 3.9e-41 140.9 29.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88528.1 - 1.6e-06 26.9 24.5 6.1e-06 25.0 16.4 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Nup88 PF10168.4 EIM88529.1 - 1.4e-22 79.3 4.4 1.3e-08 33.1 0.0 3.2 3 0 0 3 3 3 3 Nuclear pore component Nup54 PF13874.1 EIM88529.1 - 0.0059 16.2 8.2 0.0059 16.2 5.7 2.2 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Proteasome PF00227.21 EIM88530.1 - 1.5e-46 158.0 0.0 1.9e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM88530.1 - 4.1e-13 48.3 0.1 7.3e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RecA PF00154.16 EIM88530.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PCI_Csn8 PF10075.4 EIM88531.1 - 5.4e-33 113.7 0.0 1e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIM88531.1 - 2.1e-32 112.3 0.0 3.5e-32 111.6 0.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Proteasome PF00227.21 EIM88532.1 - 8.4e-40 136.0 0.0 9.6e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Nsp1_C PF05064.8 EIM88534.1 - 1.3e-31 108.6 0.2 8.9e-31 105.9 0.1 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EIM88534.1 - 3.7e-17 62.5 160.5 1.4e-08 34.9 37.5 5.8 1 1 4 5 5 5 4 Nucleoporin FG repeat region Laminin_II PF06009.7 EIM88534.1 - 0.022 14.5 1.3 0.43 10.3 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II FANCF PF11107.3 EIM88534.1 - 0.11 11.7 0.4 0.16 11.2 0.3 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) MCPsignal PF00015.16 EIM88534.1 - 0.13 11.7 2.4 2.2 7.7 0.1 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.1 EIM88534.1 - 0.18 10.2 1.0 0.33 9.3 0.4 1.4 1 1 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 EIM88534.1 - 1.5 8.7 3.0 6.6 6.7 0.1 3.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EIM88534.1 - 1.7 7.6 5.2 2.3 7.1 2.8 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EIM88534.1 - 8 6.9 7.7 35 4.8 0.1 3.2 1 1 1 3 3 3 0 Syntaxin 6, N-terminal UbiA PF01040.13 EIM88535.1 - 2e-36 125.5 17.5 2.6e-36 125.1 12.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ytp1 PF10355.4 EIM88536.1 - 5.8e-88 294.6 9.0 9.4e-88 293.9 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIM88536.1 - 2.6e-15 55.8 0.3 2.6e-15 55.8 0.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1129 PF06570.6 EIM88536.1 - 0.0018 17.6 0.1 0.041 13.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1129) Packaging_FI PF14000.1 EIM88536.1 - 0.21 11.7 1.8 0.36 11.0 1.2 1.3 1 0 0 1 1 1 0 DNA packaging protein FI MFS_1 PF07690.11 EIM88537.1 - 9.4e-35 119.9 14.5 2.9e-34 118.3 9.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PAP2 PF01569.16 EIM88537.1 - 1.1 8.9 9.2 0.6 9.7 0.2 3.3 3 0 0 3 3 3 0 PAP2 superfamily CD99L2 PF12301.3 EIM88537.1 - 1.1 8.8 5.3 1.8 8.2 3.7 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF4131 PF13567.1 EIM88537.1 - 9.4 5.6 12.4 5 6.5 1.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Rho_GDI PF02115.12 EIM88538.1 - 4.3e-48 163.3 0.0 4.7e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MSC PF09402.5 EIM88538.1 - 0.19 10.4 0.4 0.3 9.7 0.3 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Packaging_FI PF14000.1 EIM88539.1 - 0.05 13.8 0.2 0.08 13.1 0.1 1.2 1 0 0 1 1 1 0 DNA packaging protein FI zf-CCHH PF10283.4 EIM88539.1 - 0.16 11.8 10.2 1.3 8.9 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif Toxin_19 PF08088.7 EIM88539.1 - 6.3 6.7 13.4 1.2 9.1 4.7 2.4 2 0 0 2 2 2 0 Conotoxin I-superfamily zf-CCCH PF00642.19 EIM88540.1 - 0.18 11.5 19.4 0.066 12.9 1.3 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TraB PF01963.12 EIM88541.1 - 0.013 15.0 0.3 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 TraB family zf-CCCH PF00642.19 EIM88541.1 - 0.027 14.1 1.9 0.049 13.3 1.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GFO_IDH_MocA PF01408.17 EIM88542.1 - 1.4e-17 64.2 0.1 2.6e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIM88542.1 - 1.7e-06 27.8 0.0 7.2e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sclerostin PF05463.6 EIM88542.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) DUF448 PF04296.8 EIM88543.1 - 0.0026 17.3 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF448) EAF PF09816.4 EIM88544.1 - 2.4e-14 53.1 0.2 8.5e-14 51.4 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription elongation factor Ferritin_2 PF13668.1 EIM88545.1 - 2.4e-33 114.9 1.7 2.4e-33 114.9 1.2 1.7 2 0 0 2 2 2 1 Ferritin-like domain Peptidase_S10 PF00450.17 EIM88546.1 - 4.3e-103 345.6 0.2 5.5e-103 345.3 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.13 EIM88547.1 - 1.5e-57 193.0 0.3 2.9e-57 192.1 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIM88547.1 - 7.2e-28 96.1 0.2 1.2e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIM88547.1 - 6.7e-19 67.8 0.2 1.8e-18 66.4 0.2 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pex2_Pex12 PF04757.9 EIM88548.1 - 4.9e-33 114.4 5.6 6.5e-33 114.0 3.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 EIM88548.1 - 7.1e-05 22.4 0.6 7.1e-05 22.4 0.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIM88548.1 - 0.0015 18.3 3.5 0.0055 16.5 0.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIM88548.1 - 0.0015 18.5 1.5 0.0015 18.5 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM88548.1 - 0.0015 18.3 0.9 0.0041 16.9 0.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM88548.1 - 0.0079 15.8 0.1 0.025 14.2 0.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EIM88548.1 - 0.038 13.6 3.6 0.067 12.8 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM88548.1 - 0.13 11.9 3.8 0.3 10.7 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.14 EIM88549.1 - 4.9e-11 42.3 1.4 1.2e-10 41.1 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EIM88549.1 - 0.0016 18.4 2.2 0.0057 16.5 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.2 EIM88549.1 - 0.021 14.6 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Slx4 PF09494.5 EIM88550.1 - 2.4e-05 23.9 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Prok-RING_2 PF14445.1 EIM88550.1 - 0.32 10.9 1.2 0.39 10.6 0.1 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Mur_ligase_M PF08245.7 EIM88551.1 - 0.00013 22.0 0.0 0.0094 16.0 0.0 2.7 1 1 0 1 1 1 1 Mur ligase middle domain AAA_22 PF13401.1 EIM88552.1 - 0.056 13.5 0.0 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Vps52 PF04129.7 EIM88553.1 - 1.5e-60 205.1 0.5 1.6e-42 145.7 0.0 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 EIM88553.1 - 1.3e-07 30.2 0.0 0.012 13.7 0.0 3.1 2 1 0 3 3 3 2 Exocyst complex component Sec3 PrkA PF06798.7 EIM88553.1 - 0.021 14.1 0.4 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain MscS_porin PF12795.2 EIM88553.1 - 0.12 11.6 2.1 0.15 11.3 0.1 2.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain FAM163 PF15069.1 EIM88554.1 - 0.045 14.3 0.1 0.09 13.3 0.1 1.5 1 0 0 1 1 1 0 FAM163 family BAP PF06639.6 EIM88554.1 - 0.072 12.8 0.3 0.21 11.3 0.2 1.7 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Tic20 PF09685.5 EIM88554.1 - 9.7 6.2 9.1 1.2 9.1 1.4 2.2 2 0 0 2 2 2 0 Tic20-like protein TGS PF02824.16 EIM88555.1 - 2.3e-23 81.7 0.0 4.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIM88555.1 - 3.9e-18 65.4 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM88555.1 - 5.5e-09 35.4 0.1 1.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIM88555.1 - 0.0073 16.1 0.6 3.8 7.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EIM88555.1 - 0.014 14.2 1.1 0.022 13.5 0.2 1.7 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 EIM88555.1 - 0.11 11.8 0.6 6.8 6.0 0.1 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Alg6_Alg8 PF03155.10 EIM88556.1 - 4.1e-127 424.8 32.2 5.1e-125 417.9 19.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.17 EIM88557.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EIM88557.1 - 0.00013 21.0 0.1 0.0018 17.2 0.1 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EIM88557.1 - 0.0017 18.8 0.0 0.0022 18.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily VMA21 PF09446.5 EIM88558.1 - 1.9e-11 43.6 4.3 2.7e-11 43.2 3.0 1.2 1 0 0 1 1 1 1 VMA21-like domain Acetyltransf_3 PF13302.1 EIM88559.1 - 5e-10 39.6 0.0 6.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM88559.1 - 1.3e-08 34.9 0.0 1.9e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM88559.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM88559.1 - 1.4e-05 25.2 0.0 2.4e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM88559.1 - 0.00022 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIM88559.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM88559.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4241 PF14025.1 EIM88559.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Ribonuc_red_sm PF00268.16 EIM88560.1 - 4.2e-119 396.7 0.9 5.2e-119 396.4 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 EIM88561.1 - 3.7e-118 393.6 0.8 4.5e-118 393.3 0.6 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuclease_3 PF00636.21 EIM88562.1 - 2.5e-39 134.2 0.0 2e-19 70.1 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIM88562.1 - 8.1e-23 80.7 0.0 8.5e-12 45.1 0.0 4.4 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EIM88562.1 - 1.2e-10 40.9 0.0 3.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.17 EIM88562.1 - 6.6e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Helicase_C PF00271.26 EIM88562.1 - 0.00037 20.3 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain COX7C PF02935.11 EIM88563.1 - 2.5e-12 46.4 0.5 2.8e-12 46.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.17 EIM88564.1 - 2.1e-178 593.4 0.1 2.4e-178 593.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 EIM88565.1 - 6.8e-06 25.8 5.9 9.5e-06 25.4 4.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 EIM88566.1 - 3.3e-61 205.9 0.0 4.8e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM88566.1 - 3.5e-09 35.8 0.2 8.5e-09 34.5 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.16 EIM88567.1 - 3.5e-34 117.1 0.0 4.6e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM88567.1 - 3.8e-14 52.4 0.0 5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIM88567.1 - 5.6e-11 41.9 0.0 1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.8 EIM88568.1 - 4.9e-72 241.3 0.0 5.4e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SNARE_assoc PF09335.6 EIM88569.1 - 2.2e-13 50.5 10.8 2.2e-13 50.5 7.5 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 EIM88569.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.2 4 0 0 4 4 4 0 HAMP domain Cys_Met_Meta_PP PF01053.15 EIM88570.1 - 1.9e-56 191.0 0.0 3.1e-55 187.0 0.0 2.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DPBB_1 PF03330.13 EIM88571.1 - 2.5e-06 27.3 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel WD40 PF00400.27 EIM88572.1 - 6.3e-77 250.9 23.6 3.3e-09 36.2 0.0 12.1 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 EIM88572.1 - 1e-14 54.3 0.2 1.6e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EIM88572.1 - 1.8e-09 36.8 4.1 0.0075 15.0 0.1 5.2 3 1 1 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 EIM88572.1 - 4.1e-07 28.5 10.6 0.011 13.9 0.7 5.1 3 3 1 5 5 5 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EIM88572.1 - 0.0029 17.0 0.0 4.4 6.8 0.0 4.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_28 PF00295.12 EIM88572.1 - 0.032 13.1 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Peptidase_M18 PF02127.10 EIM88573.1 - 1.1e-151 505.2 0.0 1.2e-151 505.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EIM88573.1 - 0.0011 17.8 0.0 0.25 10.0 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Brix PF04427.13 EIM88574.1 - 2.3e-49 167.6 1.2 3e-49 167.2 0.8 1.1 1 0 0 1 1 1 1 Brix domain SMK-1 PF04802.10 EIM88575.1 - 1.1e-61 207.7 0.0 3e-61 206.3 0.0 1.7 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 EVE PF01878.13 EIM88575.1 - 3e-48 163.4 0.1 6.7e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 EVE domain MIT PF04212.13 EIM88575.1 - 0.053 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF1992 PF09350.5 EIM88576.1 - 2.5e-20 72.0 0.0 5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TerB-C PF15615.1 EIM88576.1 - 0.1 12.8 0.9 0.18 12.0 0.1 1.7 1 1 1 2 2 2 0 TerB-C domain RhoGEF PF00621.15 EIM88577.1 - 1.4e-18 67.3 0.0 6e-14 52.3 0.0 3.0 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 EIM88577.1 - 0.014 15.5 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 PH domain SNARE PF05739.14 EIM88579.1 - 1.7e-15 56.3 3.1 6.7e-15 54.5 2.2 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EIM88579.1 - 9.7e-06 25.6 1.1 9.7e-06 25.6 0.7 2.9 1 1 1 2 2 2 1 Syntaxin Fusion_gly PF00523.13 EIM88579.1 - 0.008 14.2 0.2 0.014 13.4 0.1 1.4 1 0 0 1 1 1 1 Fusion glycoprotein F0 DUF912 PF06024.7 EIM88579.1 - 0.015 15.3 0.2 0.042 13.8 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2580 PF10824.3 EIM88579.1 - 0.044 14.1 4.6 0.12 12.7 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2580) Use1 PF09753.4 EIM88579.1 - 0.095 12.1 3.6 0.16 11.4 2.5 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 SID-1_RNA_chan PF13965.1 EIM88579.1 - 0.097 10.8 0.8 0.12 10.4 0.4 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Z1 PF10593.4 EIM88579.1 - 0.11 11.6 1.8 0.37 9.9 0.1 2.0 2 0 0 2 2 2 0 Z1 domain DUF4105 PF13387.1 EIM88579.1 - 0.11 11.6 0.1 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) PBP1_TM PF14812.1 EIM88579.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.1 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_Mycoplasma PF07672.8 EIM88579.1 - 0.16 11.0 3.4 0.31 10.1 2.4 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF3899 PF13038.1 EIM88579.1 - 0.42 10.7 9.7 3.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Rifin_STEVOR PF02009.11 EIM88579.1 - 0.5 9.9 7.4 0.24 11.0 2.7 2.0 1 1 1 2 2 2 0 Rifin/stevor family Tropomyosin_1 PF12718.2 EIM88579.1 - 7.7 6.3 8.7 1.1 9.1 1.3 2.6 3 0 0 3 3 3 0 Tropomyosin like VPS28 PF03997.7 EIM88580.1 - 2.2e-59 200.2 0.0 2.6e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Oxidored_FMN PF00724.15 EIM88581.1 - 2.6e-92 309.4 0.0 2.9e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4050 PF13259.1 EIM88582.1 - 2.7e-05 24.0 0.0 0.00021 21.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) LRR_4 PF12799.2 EIM88583.1 - 1.6e-10 40.3 3.7 0.004 16.7 0.0 6.4 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM88583.1 - 3.2e-10 39.5 2.7 3.2e-10 39.5 1.9 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EIM88583.1 - 9.1e-06 25.2 3.2 57 4.2 0.1 8.7 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.28 EIM88583.1 - 2e-05 23.9 9.2 1.1 9.5 0.1 7.5 9 1 0 9 9 9 1 Leucine Rich Repeat F-box PF00646.28 EIM88583.1 - 0.0072 15.9 0.7 0.024 14.2 0.5 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EIM88583.1 - 0.0077 15.9 13.8 0.15 11.7 0.1 5.5 4 2 3 7 7 7 1 Leucine rich repeat LRR_7 PF13504.1 EIM88583.1 - 5.1 7.7 12.0 8.6 7.0 0.1 6.1 8 0 0 8 8 8 0 Leucine rich repeat Ste50p-SAM PF09235.5 EIM88583.1 - 5.7 7.0 6.5 11 6.1 0.0 4.0 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Lipase_GDSL_2 PF13472.1 EIM88584.1 - 4.5e-11 43.2 0.7 5.9e-11 42.8 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM88584.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Tubulin PF00091.20 EIM88585.1 - 8.2e-68 228.4 0.0 1.2e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIM88585.1 - 1.6e-45 154.1 0.0 2.4e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIM88585.1 - 8.9e-05 22.0 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EIM88586.1 - 2.2e-66 223.7 0.0 3e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIM88586.1 - 2.4e-47 160.1 0.0 3.9e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIM88586.1 - 0.011 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Dimer_Tnp_hAT PF05699.9 EIM88588.1 - 2.8e-06 26.8 0.3 0.032 13.8 0.0 2.9 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region Abhydrolase_3 PF07859.8 EIM88589.1 - 3.2e-34 118.3 0.1 4.5e-27 95.0 0.1 2.9 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM88589.1 - 2.5e-07 29.6 0.0 3e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIM88589.1 - 0.059 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family RELT PF12606.3 EIM88589.1 - 0.27 10.3 1.4 4.4 6.5 0.0 2.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DUF2264 PF10022.4 EIM88590.1 - 1.5e-132 441.6 0.1 1.8e-132 441.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DSPc PF00782.15 EIM88591.1 - 9.7e-29 99.6 0.0 1.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM88591.1 - 0.058 12.7 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SOG2 PF10428.4 EIM88592.1 - 3.8 6.0 9.6 4.7 5.7 6.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TAF4 PF05236.9 EIM88593.1 - 3.8e-30 105.0 0.3 7.9e-30 104.0 0.2 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4407 PF14362.1 EIM88593.1 - 1 8.2 12.4 0.58 9.0 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAF-AH_p_II PF03403.8 EIM88594.1 - 1.3e-36 125.7 0.0 1.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EIM88594.1 - 1e-07 31.8 0.0 2.4e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIM88594.1 - 0.0046 15.8 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIM88594.1 - 0.049 12.4 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase tRNA-synt_1c PF00749.16 EIM88595.1 - 1.3e-103 346.0 0.0 1.8e-103 345.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIM88595.1 - 1.2e-32 112.9 0.0 2.5e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EIM88595.1 - 1.9e-29 102.3 0.1 2.9e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EIM88595.1 - 2.5e-11 44.0 4.6 7.7e-11 42.5 3.2 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.17 EIM88596.1 - 1.7e-62 211.4 0.0 2.9e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EIM88598.1 - 3e-42 144.6 8.3 3.6e-42 144.4 5.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pex14_N PF04695.8 EIM88599.1 - 4.5e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidase PF01425.16 EIM88601.1 - 2.8e-56 191.2 0.0 3.5e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Amidase WD40 PF00400.27 EIM88602.1 - 1.5e-09 37.3 4.8 0.17 11.8 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Daxx PF03344.10 EIM88602.1 - 1.4 7.3 7.0 2 6.7 4.9 1.1 1 0 0 1 1 1 0 Daxx Family SKN1 PF03935.10 EIM88603.1 - 3.8e-190 632.3 9.9 4.4e-190 632.1 6.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_M28 PF04389.12 EIM88605.1 - 7.9e-13 48.5 0.0 2.2e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EIM88605.1 - 1.7e-12 47.0 0.0 6e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EIM88605.1 - 0.00011 21.8 0.1 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Alpha-amylase_C PF02806.13 EIM88606.1 - 7.4e-21 74.1 0.0 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EIM88606.1 - 2e-17 63.5 0.0 5e-13 49.1 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EIM88606.1 - 6.8e-17 61.2 0.1 2.7e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RuBisCO_large PF00016.15 EIM88606.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Myb_DNA-bind_6 PF13921.1 EIM88607.1 - 1.3e-06 28.3 0.1 3.6e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIM88607.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIM88607.1 - 0.055 13.3 4.8 1 9.3 0.0 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF498 PF04430.9 EIM88608.1 - 1.3e-31 108.4 0.0 1.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.8 EIM88610.1 - 9.1e-07 28.6 10.3 2.5e-06 27.2 2.9 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EIM88610.1 - 1.9 8.3 13.5 1.4 8.7 3.5 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EIM88610.1 - 2.8 8.0 11.5 3 7.9 4.0 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EIM88610.1 - 3.7 7.6 13.2 0.26 11.3 3.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb BPL_LplA_LipB PF03099.14 EIM88612.1 - 6.8e-23 81.0 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EIM88612.1 - 2.3e-06 27.1 0.0 1.2e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus WD40 PF00400.27 EIM88613.1 - 3.7e-08 32.9 2.4 2.1 8.3 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EIM88616.1 - 3.8e-34 118.5 0.8 4.8e-34 118.2 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88616.1 - 3.8e-21 75.7 0.8 6.5e-20 71.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM88616.1 - 9.6e-18 64.3 0.1 1.3e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EIM88616.1 - 1.9e-07 30.8 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 EIM88616.1 - 0.00013 21.2 0.1 0.093 11.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EIM88616.1 - 0.00075 19.3 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EIM88616.1 - 0.00095 18.5 0.1 0.35 10.0 0.1 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EIM88616.1 - 0.0024 17.4 0.2 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIM88616.1 - 0.0052 16.5 0.0 0.03 14.0 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 EIM88616.1 - 0.05 12.4 0.1 1.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Esterase_phd PF10503.4 EIM88616.1 - 0.062 12.5 0.3 0.39 9.9 0.1 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S28 PF05577.7 EIM88616.1 - 0.2 10.2 0.2 0.3 9.6 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MFS_1 PF07690.11 EIM88617.1 - 2e-30 105.7 23.9 7.3e-25 87.4 6.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Clathrin_H_link PF13838.1 EIM88618.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Clathrin-H-link DUF1399 PF07173.7 EIM88619.1 - 1.8e-25 89.7 0.4 9.8e-20 71.2 0.0 3.0 2 2 1 3 3 3 3 Protein of unknown function (DUF1399) Macoilin PF09726.4 EIM88621.1 - 1.3 7.2 8.7 1.4 7.1 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Metallophos_2 PF12850.2 EIM88622.1 - 6.8e-09 35.7 0.2 1.2e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIM88622.1 - 9.6e-08 31.6 7.5 1.9e-07 30.6 5.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SUI1 PF01253.17 EIM88624.1 - 2.3e-21 75.3 0.3 5e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EIM88624.1 - 0.00048 20.0 0.2 0.00087 19.1 0.1 1.5 2 0 0 2 2 2 1 Transposon-encoded protein TnpV DUF3584 PF12128.3 EIM88624.1 - 0.0099 13.2 2.3 0.012 12.9 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_11 PF13414.1 EIM88626.1 - 8.3e-13 47.7 1.4 2.3e-09 36.7 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EIM88626.1 - 5.8e-07 28.8 0.1 0.1 12.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM88626.1 - 2.3e-06 27.1 2.5 0.02 14.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 EIM88626.1 - 0.00013 21.7 0.0 0.00035 20.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 EIM88626.1 - 0.013 15.1 0.7 0.055 13.1 0.0 2.4 3 0 0 3 3 3 0 DnaJ domain TPR_12 PF13424.1 EIM88626.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM88626.1 - 0.19 11.6 0.7 40 4.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM88626.1 - 0.23 12.1 0.0 0.23 12.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM88626.1 - 0.52 11.0 0.0 0.52 11.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.6 EIM88627.1 - 3.6e-101 338.6 0.0 5.6e-101 338.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIM88627.1 - 1.5e-18 66.1 0.0 1.1e-08 33.6 0.0 4.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EIM88627.1 - 9.2e-06 24.9 0.0 0.044 12.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EIM88627.1 - 0.0022 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NPV_P10 PF05531.7 EIM88627.1 - 0.084 13.1 2.1 0.2 11.9 1.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DSPc PF00782.15 EIM88628.1 - 1.7e-33 115.0 0.0 2.2e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM88628.1 - 4.1e-06 26.3 0.3 5.7e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Peptidase_M24 PF00557.19 EIM88629.1 - 8.8e-43 146.2 0.0 1.1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 p450 PF00067.17 EIM88631.1 - 3.4e-62 210.4 0.0 4.8e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GTP_cyclohydro2 PF00925.15 EIM88633.1 - 4.2e-62 208.3 0.0 3.6e-57 192.2 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II Vps5 PF09325.5 EIM88634.1 - 1.6e-18 66.8 3.7 2.2e-18 66.4 2.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIM88634.1 - 5.9e-13 48.6 0.5 1.5e-12 47.2 0.0 1.9 2 1 0 2 2 2 1 PX domain TPR_12 PF13424.1 EIM88634.1 - 0.0039 17.0 0.7 0.96 9.4 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF4200 PF13863.1 EIM88634.1 - 0.69 9.8 8.7 0.078 12.9 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Peptidase_M24 PF00557.19 EIM88635.1 - 1.3e-11 44.4 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1262 PF06880.6 EIM88635.1 - 0.14 12.4 0.1 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) Glyco_hydro_43 PF04616.9 EIM88636.1 - 1.1e-38 132.9 0.2 1.4e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PI3_PI4_kinase PF00454.22 EIM88637.1 - 1.7e-51 174.9 0.0 5.1e-51 173.4 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EIM88637.1 - 4.8e-27 94.8 0.6 8.8e-27 94.0 0.4 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EIM88637.1 - 7.4e-23 80.5 0.1 3.5e-22 78.3 0.1 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EIM88637.1 - 1.6e-11 43.4 0.0 4.2e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 EIM88637.1 - 0.041 14.2 0.0 1.1 9.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3385 PF11865.3 EIM88637.1 - 0.072 13.0 0.1 0.56 10.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) YEATS PF03366.11 EIM88638.1 - 6.1e-32 109.1 0.1 9.8e-32 108.5 0.0 1.3 1 0 0 1 1 1 1 YEATS family Dyp_perox PF04261.7 EIM88639.1 - 2e-06 26.8 0.0 6.4e-05 21.8 0.0 3.0 4 0 0 4 4 4 1 Dyp-type peroxidase family FAD_binding_6 PF00970.19 EIM88640.1 - 2.6e-12 46.6 0.0 7.7e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIM88640.1 - 4.2e-06 27.2 0.0 0.1 13.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIM88640.1 - 0.00027 20.8 0.0 0.015 15.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIM88640.1 - 0.044 13.7 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain UBN2_2 PF14227.1 EIM88644.1 - 4.7e-12 45.5 0.4 9.5e-12 44.5 0.3 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM88644.1 - 5e-08 32.7 0.5 2.8e-07 30.3 0.3 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIM88644.1 - 0.00085 18.9 0.7 0.0016 18.0 0.2 1.7 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.17 EIM88644.1 - 0.045 13.8 0.1 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SNF2_N PF00176.18 EIM88645.1 - 0.083 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ycf1 PF05758.7 EIM88646.1 - 7 4.2 7.4 8.6 3.9 5.1 1.3 1 0 0 1 1 1 0 Ycf1 Glycos_transf_N PF04413.11 EIM88648.1 - 0.08 12.1 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AAA_19 PF13245.1 EIM88649.1 - 0.00011 21.9 0.0 0.0032 17.1 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 EIM88649.1 - 0.00019 21.4 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RHSP PF07999.6 EIM88649.1 - 0.00083 18.0 0.1 0.035 12.6 0.1 2.1 1 1 0 1 1 1 1 Retrotransposon hot spot protein AAA_22 PF13401.1 EIM88649.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIM88649.1 - 0.0071 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.4 EIM88649.1 - 0.029 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_10 PF12846.2 EIM88649.1 - 0.06 12.7 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EIM88649.1 - 0.072 12.9 0.0 6.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EIM88649.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.13 EIM88649.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EIM88649.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EIM88649.1 - 0.1 11.7 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EIM88649.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EIM88649.1 - 0.2 10.6 0.0 0.67 8.8 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain cobW PF02492.14 EIM88649.1 - 0.2 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.20 EIM88650.1 - 1.3e-72 244.0 0.0 1.5e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88650.1 - 5.2e-32 110.9 0.0 1.9e-31 109.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIM88650.1 - 8.1e-05 21.7 0.2 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIM88650.1 - 0.0005 19.1 0.0 0.0015 17.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIM88650.1 - 0.0017 18.1 0.9 1.3 8.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YukC PF10140.4 EIM88650.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 EIM88650.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1877 PF08974.5 EIM88650.1 - 0.11 12.1 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) zf-CCCH PF00642.19 EIM88651.1 - 9.6e-05 21.9 7.8 0.00022 20.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zip PF02535.17 EIM88651.1 - 0.0094 14.9 5.9 0.018 14.0 4.1 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter zf-CCCH_2 PF14608.1 EIM88651.1 - 0.46 10.5 10.7 0.12 12.4 1.4 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type WD40 PF00400.27 EIM88652.1 - 6.8e-49 162.0 3.2 7.9e-08 31.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIM88652.1 - 2.5e-05 22.6 0.1 0.034 12.3 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIM88652.1 - 0.0079 14.5 0.7 0.45 8.7 0.0 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 EIM88652.1 - 0.054 13.1 0.4 6.8 6.4 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hira PF07569.6 EIM88652.1 - 0.13 11.4 0.0 1.7 7.8 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split Condensation PF00668.15 EIM88654.1 - 6.9e-81 271.3 0.0 1.3e-28 99.6 0.0 4.4 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 EIM88654.1 - 7.3e-80 268.3 0.0 5.1e-79 265.6 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EIM88654.1 - 1e-20 73.7 3.5 1.5e-07 31.5 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EIM88654.1 - 0.006 17.4 0.1 0.025 15.5 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AATase PF07247.7 EIM88654.1 - 0.17 10.3 0.0 2.4 6.5 0.0 2.4 3 0 0 3 3 3 0 Alcohol acetyltransferase PSRP-3_Ycf65 PF04839.8 EIM88654.1 - 0.2 11.7 0.0 0.75 9.9 0.0 2.0 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) ECH PF00378.15 EIM88655.1 - 3.5e-60 203.1 0.0 4.2e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_2 PF07992.9 EIM88658.1 - 1.2e-16 61.2 0.1 2.1e-07 31.0 0.0 3.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM88658.1 - 2.3e-14 53.5 0.2 5.1e-11 42.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM88658.1 - 1.6e-12 47.9 0.1 4.2e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM88658.1 - 6.9e-07 28.4 0.0 0.23 10.3 0.1 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIM88658.1 - 3.7e-06 26.0 0.1 0.00026 20.0 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIM88658.1 - 0.00012 20.8 0.3 0.36 9.3 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.13 EIM88658.1 - 0.0012 18.8 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_7 PF13241.1 EIM88658.1 - 0.0015 18.7 0.6 0.24 11.6 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIM88658.1 - 0.0019 17.9 0.1 1.3 8.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding SIS PF01380.17 EIM88658.1 - 0.017 14.7 0.2 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 SIS domain HI0933_like PF03486.9 EIM88658.1 - 0.085 11.3 0.0 3.8 5.8 0.0 2.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EIM88658.1 - 0.098 11.5 0.0 14 4.4 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein Gemini_C4 PF01492.12 EIM88658.1 - 0.15 11.8 1.0 1 9.1 0.8 2.2 2 0 0 2 2 2 0 Geminivirus C4 protein K_oxygenase PF13434.1 EIM88659.1 - 2.5e-81 273.2 0.0 1.5e-80 270.6 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIM88659.1 - 1.5e-07 31.7 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM88659.1 - 1.5e-06 28.1 0.0 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Acetyltransf_8 PF13523.1 EIM88660.1 - 3e-28 98.6 0.2 6.2e-28 97.5 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EIM88661.1 - 9e-13 47.6 53.5 4.1e-11 42.1 22.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIM88663.1 - 1.8e-08 33.4 45.5 9.8e-08 31.0 15.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3260 PF11658.3 EIM88666.1 - 0.0046 15.1 0.0 0.0055 14.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) Myb_DNA-bind_3 PF12776.2 EIM88667.1 - 9e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIM88667.1 - 0.0018 18.3 0.1 0.03 14.4 0.0 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain BUD22 PF09073.5 EIM88667.1 - 0.038 13.0 2.9 0.11 11.5 2.0 1.8 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 EIM88667.1 - 0.17 11.2 12.8 0.28 10.5 8.9 1.3 1 0 0 1 1 1 0 Vta1 like Sigma70_ner PF04546.8 EIM88667.1 - 0.31 10.6 4.7 0.69 9.4 3.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Prothymosin PF03247.9 EIM88667.1 - 0.74 9.9 18.8 1.5 9.0 13.0 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 EIM88667.1 - 1.1 9.5 17.9 2 8.6 12.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 EIM88669.1 - 3.5e-13 49.3 0.0 8.9e-12 44.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88669.1 - 0.00071 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_membrane PF00664.18 EIM88670.1 - 1.2e-55 188.8 26.3 5.6e-31 107.9 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM88670.1 - 9.1e-50 168.5 0.0 1.6e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIM88670.1 - 4.3e-10 39.2 0.7 0.003 16.8 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM88670.1 - 4.7e-05 22.8 0.2 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM88670.1 - 5.6e-05 22.5 0.9 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIM88670.1 - 5.7e-05 23.2 0.0 1.4 8.8 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM88670.1 - 7e-05 22.8 0.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIM88670.1 - 0.00011 21.7 0.1 0.033 13.6 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EIM88670.1 - 0.0022 17.9 0.5 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EIM88670.1 - 0.0032 18.2 0.5 1.2 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIM88670.1 - 0.0032 16.9 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EIM88670.1 - 0.0072 15.4 0.6 1.7 7.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EIM88670.1 - 0.0095 16.2 5.7 0.9 9.8 0.1 2.6 3 0 0 3 3 2 2 AAA domain TrwB_AAD_bind PF10412.4 EIM88670.1 - 0.01 14.4 0.5 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EIM88670.1 - 0.012 15.3 0.4 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIM88670.1 - 0.013 15.6 1.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EIM88670.1 - 0.013 15.9 1.2 1.9 9.0 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein ATP_bind_1 PF03029.12 EIM88670.1 - 0.016 14.7 2.6 5.4 6.4 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIM88670.1 - 0.018 14.6 0.3 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EIM88670.1 - 0.023 13.8 2.0 0.64 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIM88670.1 - 0.028 14.0 1.5 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 EIM88670.1 - 0.064 13.0 3.8 0.12 12.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EIM88670.1 - 0.14 11.5 2.1 1.8 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EIM88670.1 - 0.21 11.7 0.2 41 4.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 EIM88670.1 - 0.3 10.5 0.2 14 5.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EIM88670.1 - 0.34 11.2 4.2 1.7 8.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIM88670.1 - 0.42 9.4 2.0 0.93 8.2 0.6 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 EIM88670.1 - 0.53 10.1 3.4 6.5 6.6 0.2 3.0 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 EIM88670.1 - 0.57 9.0 1.6 15 4.4 0.3 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Aldedh PF00171.17 EIM88674.1 - 1.5e-142 475.2 0.0 1.8e-142 474.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM88674.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1205 PF06722.7 EIM88674.1 - 0.073 13.3 0.2 16 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1205) p450 PF00067.17 EIM88675.1 - 4.3e-58 196.9 0.0 4.9e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM88677.1 - 2.1e-10 39.7 0.0 2.5e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.15 EIM88678.1 - 6.7e-69 232.2 0.0 8.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIM88678.1 - 1.1e-14 54.0 0.0 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EIM88678.1 - 0.0067 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Cytochrom_B561 PF03188.11 EIM88680.1 - 9.3e-11 41.7 10.7 1.1e-10 41.4 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 MatE PF01554.13 EIM88680.1 - 0.0053 16.4 2.1 0.0065 16.1 1.0 1.4 1 1 0 1 1 1 1 MatE DUF4181 PF13789.1 EIM88680.1 - 0.0095 15.8 0.1 0.0095 15.8 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4181) DUF420 PF04238.7 EIM88680.1 - 0.13 12.2 10.1 0.043 13.7 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF418 PF04235.7 EIM88680.1 - 0.16 11.6 5.2 0.23 11.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF2427 PF10348.4 EIM88680.1 - 0.34 10.5 7.8 0.15 11.6 2.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) CopD PF05425.8 EIM88680.1 - 0.79 9.9 9.9 0.053 13.7 3.0 2.0 2 1 0 2 2 2 0 Copper resistance protein D ABC2_membrane_4 PF12730.2 EIM88680.1 - 6.7 5.8 13.3 3.8 6.6 7.0 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Kinesin PF00225.18 EIM88681.1 - 2e-92 309.4 0.0 2.7e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TPR_2 PF07719.12 EIM88681.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF367 PF04034.8 EIM88684.1 - 1.5e-44 150.6 0.0 2.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EIM88684.1 - 1.4e-14 53.3 0.0 2.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Baculo_gp41 PF04700.7 EIM88685.1 - 0.0027 17.1 0.2 0.52 9.7 0.0 2.2 2 0 0 2 2 2 2 Structural glycoprotein p40/gp41 conserved region DUF1705 PF08019.7 EIM88685.1 - 0.0035 16.8 1.0 2 7.9 0.1 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1705) Abhydrolase_3 PF07859.8 EIM88685.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PIF1 PF05970.9 EIM88690.1 - 0.00018 20.6 0.1 0.24 10.3 0.0 2.3 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIM88690.1 - 0.027 14.0 0.1 9.2 5.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain Peptidase_C14 PF00656.17 EIM88691.1 - 0.061 13.0 0.0 0.33 10.6 0.0 1.9 1 1 1 2 2 2 0 Caspase domain BCDHK_Adom3 PF10436.4 EIM88692.1 - 6e-67 224.2 0.0 8.2e-67 223.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIM88692.1 - 1.8e-19 69.4 0.0 4.6e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIM88692.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 EIM88693.1 - 1.4e-21 76.6 43.7 1.4e-21 76.6 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88693.1 - 0.4 9.1 40.0 0.045 12.3 7.4 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter DUF1228 PF06779.9 EIM88693.1 - 4.6 7.3 14.5 1.6 8.7 0.9 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Ricin_B_lectin PF00652.17 EIM88694.1 - 1.3e-14 54.2 0.5 0.011 15.7 0.0 4.2 2 2 0 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIM88694.1 - 0.001 19.4 0.0 1.2 9.5 0.0 3.0 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Med3 PF11593.3 EIM88694.1 - 1.4 8.1 10.9 2.4 7.3 7.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.6 EIM88694.1 - 7.2 4.5 6.6 9.8 4.1 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_U4 PF03419.8 EIM88695.1 - 0.0017 17.4 3.8 0.0027 16.8 2.6 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA HNH_2 PF13391.1 EIM88696.1 - 2e-06 27.5 0.0 5.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Tombus_movement PF05318.7 EIM88696.1 - 0.093 13.3 0.2 0.21 12.2 0.2 1.6 1 0 0 1 1 1 0 Tombusvirus movement protein PAS_9 PF13426.1 EIM88698.1 - 7.1e-26 90.6 0.0 7.7e-17 61.5 0.0 4.4 4 1 0 4 4 4 3 PAS domain PAS PF00989.19 EIM88698.1 - 1.8e-14 53.4 0.0 7.7e-07 28.8 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 EIM88698.1 - 9.4e-10 38.5 0.0 2.1e-05 24.5 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 EIM88698.1 - 2.8e-09 36.9 0.0 0.00034 20.6 0.0 4.4 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 EIM88698.1 - 0.00012 21.7 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EIM88698.1 - 0.00054 19.8 0.0 0.003 17.4 0.0 2.2 3 0 0 3 3 3 1 PAS domain Ribosomal_L16 PF00252.13 EIM88699.1 - 3.4e-33 114.2 0.0 4.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.27 EIM88700.1 - 4.9e-69 225.9 14.2 5.8e-10 38.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EIM88700.1 - 1.9e-25 88.8 3.9 3.2e-25 88.1 2.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Gmad1 PF10647.4 EIM88700.1 - 0.00085 18.7 0.1 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EIM88700.1 - 0.00093 18.3 0.2 5.3 6.0 0.0 3.6 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIM88700.1 - 0.00097 17.9 0.3 2.3 6.8 0.0 3.4 1 1 3 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIM88700.1 - 0.0014 17.0 1.3 0.038 12.2 0.2 2.9 2 1 2 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 EIM88700.1 - 0.0042 16.7 0.1 30 4.4 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PSII_BNR PF14870.1 EIM88700.1 - 0.0074 15.3 0.1 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Nup160 PF11715.3 EIM88700.1 - 0.0076 14.4 0.1 0.37 8.8 0.0 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF3450 PF11932.3 EIM88700.1 - 0.013 14.8 0.7 0.023 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 EIM88700.1 - 0.017 13.7 0.3 0.025 13.2 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EIM88700.1 - 0.019 14.5 1.0 0.033 13.7 0.7 1.3 1 0 0 1 1 1 0 IncA protein PQQ_2 PF13360.1 EIM88700.1 - 0.051 13.0 0.6 0.46 9.9 0.1 2.3 2 1 1 3 3 3 0 PQQ-like domain Proteasome_A_N PF10584.4 EIM88700.1 - 0.19 11.0 3.0 80 2.6 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CENP-F_leu_zip PF10473.4 EIM88700.1 - 0.58 10.0 8.0 0.022 14.6 1.5 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAT1 PF09770.4 EIM88700.1 - 4.8 5.3 8.6 7.2 4.7 6.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EIM88700.1 - 6.8 5.9 17.8 9.9 5.4 12.3 1.2 1 0 0 1 1 1 0 Vta1 like ADH_N PF08240.7 EIM88701.1 - 8.8e-24 83.3 0.0 1.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM88701.1 - 7.4e-05 22.3 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM88701.1 - 0.0036 18.1 0.0 0.02 15.8 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase mono-CXXC PF15626.1 EIM88701.1 - 0.23 11.3 2.3 0.55 10.2 1.6 1.6 1 0 0 1 1 1 0 single CXXC unit FAD_binding_3 PF01494.14 EIM88702.1 - 1.9e-70 237.7 0.0 2.3e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIM88702.1 - 7.4e-06 26.2 0.1 0.007 16.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM88702.1 - 2.3e-05 24.3 0.2 6.8e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM88702.1 - 5.2e-05 22.4 0.0 8.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIM88702.1 - 0.00022 21.1 0.1 0.00052 19.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM88702.1 - 0.00069 18.3 0.2 0.003 16.2 0.0 1.8 1 1 1 2 2 2 1 Tryptophan halogenase DAO PF01266.19 EIM88702.1 - 0.00077 18.4 0.1 0.0015 17.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM88702.1 - 0.00089 18.2 0.1 0.0035 16.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM88702.1 - 0.0038 15.7 1.1 0.0054 15.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EIM88702.1 - 0.0042 16.0 0.2 0.0061 15.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM88702.1 - 0.0042 17.1 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM88702.1 - 0.011 14.8 0.5 0.02 13.9 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EIM88702.1 - 0.042 12.6 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Peroxidase_2 PF01328.12 EIM88703.1 - 1.8e-23 82.6 0.0 3.1e-23 81.9 0.0 1.3 1 1 0 1 1 1 1 Peroxidase, family 2 HMG_CoA_synt_N PF01154.12 EIM88704.1 - 7.1e-82 273.1 0.2 1.4e-81 272.2 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EIM88704.1 - 1.8e-79 267.1 0.2 4e-79 266.0 0.1 1.6 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.5 EIM88704.1 - 0.017 14.7 1.2 0.031 13.9 0.1 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EIM88704.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Terpene_synth_C PF03936.11 EIM88705.1 - 1.7e-11 43.8 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ER_lumen_recept PF00810.13 EIM88706.1 - 2.1e-10 41.2 0.7 1e-09 39.0 0.0 2.3 1 1 1 2 2 2 1 ER lumen protein retaining receptor HMG_CoA_synt_C PF08540.5 EIM88708.1 - 8.5e-86 287.9 0.1 2.9e-85 286.1 0.1 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EIM88708.1 - 4e-82 273.9 0.1 6.7e-82 273.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EIM88708.1 - 0.0099 15.5 0.2 0.039 13.6 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EIM88708.1 - 0.092 12.7 0.1 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.17 EIM88709.1 - 6.5e-65 219.4 0.0 1.8e-64 217.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EIM88710.1 - 2.5e-14 53.3 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88710.1 - 1.3e-12 47.5 0.0 5.9e-06 25.9 0.0 2.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88710.1 - 1e-11 45.1 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM88710.1 - 1.1e-08 35.6 0.0 2.4e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88710.1 - 3.1e-08 33.9 0.0 8.6e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88710.1 - 5.8e-05 23.1 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM88710.1 - 9.3e-05 22.7 0.0 0.0016 18.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIM88710.1 - 0.00047 19.8 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 EIM88710.1 - 0.00052 19.1 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EIM88710.1 - 0.0027 16.8 0.0 0.013 14.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EIM88710.1 - 0.0039 16.4 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 EIM88710.1 - 0.005 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 EIM88710.1 - 0.0067 15.5 0.0 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EIM88710.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EIM88710.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EIM88710.1 - 0.046 13.6 0.0 0.097 12.6 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EIM88710.1 - 0.17 11.3 0.0 0.45 10.0 0.0 1.8 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_3 PF13738.1 EIM88711.1 - 1.2e-23 84.2 0.0 1.7e-22 80.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM88711.1 - 3.6e-20 71.6 0.0 4.4e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM88711.1 - 1.8e-11 43.5 0.0 4.4e-09 35.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM88711.1 - 1.3e-10 41.4 0.0 2.2e-08 34.2 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM88711.1 - 3.6e-06 27.1 0.2 0.022 14.8 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EIM88711.1 - 1.9e-05 23.8 0.0 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM88711.1 - 4.1e-05 22.2 0.8 0.00019 20.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EIM88711.1 - 5.2e-05 23.2 0.0 0.00019 21.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM88711.1 - 0.00018 20.5 0.2 0.01 14.7 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM88711.1 - 0.00029 21.1 0.4 0.037 14.4 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM88711.1 - 0.00031 20.5 0.1 0.043 13.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIM88711.1 - 0.00035 19.5 0.1 0.0011 17.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EIM88711.1 - 0.00098 18.7 0.1 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EIM88711.1 - 0.0035 16.4 0.0 0.68 8.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EIM88711.1 - 0.0037 16.1 0.1 0.038 12.8 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIM88711.1 - 0.0039 16.3 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 EIM88711.1 - 0.004 17.2 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Thi4 PF01946.12 EIM88711.1 - 0.0084 15.2 0.2 0.036 13.1 0.0 2.1 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.13 EIM88711.1 - 0.027 14.4 0.0 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EIM88711.1 - 0.044 12.9 0.0 0.39 9.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIM88711.1 - 0.069 12.8 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIM88711.1 - 0.078 13.2 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.16 EIM88711.1 - 0.14 11.9 0.3 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 ThiF family Polysacc_deac_1 PF01522.16 EIM88713.1 - 1.5e-11 43.9 0.0 3.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase HD_3 PF13023.1 EIM88714.1 - 2.4e-42 144.4 0.7 3e-42 144.1 0.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EIM88714.1 - 2.8e-06 27.3 0.5 5.2e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 HD domain YopR_core PF09025.5 EIM88714.1 - 0.055 13.4 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 YopR Core RyR PF02026.11 EIM88714.1 - 0.12 12.3 0.9 0.25 11.3 0.2 1.7 2 0 0 2 2 2 0 RyR domain FHA PF00498.21 EIM88715.1 - 1.1e-14 54.2 0.0 3.7e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 FHA domain Lipoprotein_7 PF01540.11 EIM88715.1 - 0.027 13.5 0.6 0.045 12.8 0.4 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein DUF1664 PF07889.7 EIM88715.1 - 0.28 10.9 12.4 0.19 11.4 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EIM88715.1 - 2.5 7.2 9.2 4.5 6.3 2.4 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIM88715.1 - 4 5.7 7.9 0.87 7.9 1.6 2.1 2 0 0 2 2 2 0 AAA domain Cu-oxidase PF00394.17 EIM88718.1 - 3.2e-44 150.6 0.7 1.8e-41 141.6 0.0 2.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM88718.1 - 6.9e-38 129.2 5.9 6.4e-35 119.6 0.1 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM88718.1 - 2.6e-37 127.1 0.5 1.4e-35 121.5 0.3 2.6 2 0 0 2 2 2 1 Multicopper oxidase SWM_repeat PF13753.1 EIM88718.1 - 0.0067 15.5 0.1 0.0067 15.5 0.1 2.5 3 0 0 3 3 3 1 Putative flagellar system-associated repeat p450 PF00067.17 EIM88719.1 - 2.2e-64 217.6 0.0 6.7e-64 216.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.7 EIM88720.1 - 3.1e-13 49.8 19.4 8.3e-07 29.4 0.1 6.7 7 0 0 7 7 7 3 Sel1 repeat TPR_14 PF13428.1 EIM88720.1 - 0.0051 17.3 2.1 11 7.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM88720.1 - 0.043 14.4 6.8 0.11 13.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM88720.1 - 0.071 13.0 9.0 0.17 11.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM88720.1 - 0.11 12.3 0.1 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM88720.1 - 0.99 9.1 8.9 0.14 11.8 0.2 3.4 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 EIM88720.1 - 4.2 7.1 9.2 3 7.6 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3602 PF12223.3 EIM88721.1 - 1.3e-14 54.3 16.6 2.5e-05 24.5 1.1 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) KAR9 PF08580.5 EIM88721.1 - 4 5.5 6.0 4.6 5.4 4.1 1.3 1 1 0 1 1 1 0 Yeast cortical protein KAR9 adh_short PF00106.20 EIM88722.1 - 1.2e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EIM88722.1 - 1.9e-08 34.0 0.1 6.1e-08 32.3 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM88722.1 - 3.7e-07 29.9 0.0 6.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM88722.1 - 0.00015 21.7 0.0 0.00052 20.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EIM88722.1 - 0.058 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase BTB PF00651.26 EIM88724.1 - 5.8e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM88725.1 - 1.8e-07 31.1 0.1 3.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain HCNGP PF07818.8 EIM88726.1 - 5.6e-15 55.1 0.1 5.6e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 HCNGP-like protein Mito_fiss_reg PF05308.6 EIM88726.1 - 4.3 6.6 7.5 0.22 10.8 0.8 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator DnaJ PF00226.26 EIM88727.1 - 1.7e-20 72.5 0.6 2e-17 62.6 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain tRNA-synt_1c PF00749.16 EIM88727.1 - 0.37 9.4 7.3 0.52 8.9 5.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain p450 PF00067.17 EIM88728.1 - 5.4e-67 226.3 0.0 6.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EIM88729.1 - 1.9e-96 323.6 0.0 2.2e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.23 EIM88730.1 - 5.4e-71 239.1 0.0 7.1e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM88730.1 - 0.00042 21.2 0.0 0.00099 20.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MR_MLE_C PF13378.1 EIM88731.1 - 3e-16 59.3 0.0 6.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIM88731.1 - 5.8e-12 45.9 0.0 1.6e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIM88731.1 - 7.5e-07 29.1 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain FAD_binding_3 PF01494.14 EIM88732.1 - 2.3e-17 63.0 0.0 9.3e-16 57.8 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM88732.1 - 9.6e-07 28.7 0.7 2.8e-05 24.0 0.8 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM88732.1 - 0.0021 16.7 1.9 0.0027 16.4 0.3 1.8 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 EIM88732.1 - 0.017 14.0 0.6 0.027 13.3 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIM88732.1 - 0.14 11.2 0.5 0.25 10.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EIM88732.1 - 0.24 9.8 0.8 2.2 6.6 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EIM88732.1 - 1.5 7.5 3.5 2.7 6.7 2.4 1.3 1 0 0 1 1 1 0 FAD binding domain Fez1 PF06818.10 EIM88733.1 - 0.017 15.1 3.4 0.03 14.3 2.4 1.3 1 0 0 1 1 1 0 Fez1 APG6 PF04111.7 EIM88733.1 - 0.025 13.6 3.4 0.039 13.0 2.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Brevenin PF03032.10 EIM88733.1 - 0.44 10.4 2.9 1.7 8.5 2.0 2.0 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family DUF4544 PF15077.1 EIM88733.1 - 2.8 7.3 6.2 0.84 9.0 0.6 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4544) Macoilin PF09726.4 EIM88733.1 - 4.8 5.3 10.3 11 4.1 7.2 1.5 1 0 0 1 1 1 0 Transmembrane protein Zn_Tnp_IS1595 PF12760.2 EIM88734.1 - 0.013 15.3 2.0 0.037 13.8 1.4 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PBP1_TM PF14812.1 EIM88734.1 - 0.24 11.7 2.8 0.72 10.1 1.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_3 PF01494.14 EIM88735.1 - 1.7e-18 66.7 0.2 3.9e-08 32.7 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM88735.1 - 0.00017 21.5 0.3 0.00046 20.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM88735.1 - 0.00028 19.9 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EIM88735.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 EIM88735.1 - 0.23 10.0 0.2 0.43 9.1 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase BTB PF00651.26 EIM88736.1 - 6.2e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain LSM PF01423.17 EIM88738.1 - 3.8e-18 64.8 0.6 4.9e-18 64.4 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIM88738.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 EIM88738.1 - 0.03 13.9 0.3 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain API5 PF05918.6 EIM88738.1 - 0.095 11.1 2.7 0.12 10.8 1.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gemin7 PF11095.3 EIM88738.1 - 0.097 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BTB PF00651.26 EIM88739.1 - 2.2e-10 40.5 0.0 2.8e-09 36.9 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 EIM88739.1 - 1.6e-09 37.3 0.9 2.7e-08 33.3 0.4 2.4 2 0 0 2 2 2 1 CAP-Gly domain WD40 PF00400.27 EIM88740.1 - 4e-52 172.3 22.3 7.7e-09 35.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM88740.1 - 0.00012 20.9 1.0 0.061 12.0 0.1 2.4 2 0 0 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.1 EIM88740.1 - 0.074 13.3 9.1 0.86 9.9 0.1 4.4 3 2 1 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 EIM88740.1 - 0.085 12.2 1.5 13 5.2 0.1 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 EIM88740.1 - 0.4 10.9 6.2 11 6.4 0.1 3.8 5 0 0 5 5 5 0 Kelch motif NAD_binding_4 PF07993.7 EIM88743.1 - 4.3e-33 114.2 0.0 8.1e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM88743.1 - 7e-30 103.7 0.0 2.3e-29 102.0 0.0 1.9 2 1 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EIM88743.1 - 2.7e-07 30.2 0.0 9.9e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM88743.1 - 0.0024 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIM88743.1 - 0.41 9.3 0.0 1.1 7.8 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GMC_oxred_N PF00732.14 EIM88744.1 - 2.8e-59 200.7 0.0 3.9e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM88744.1 - 2.1e-39 135.1 0.0 6e-39 133.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM88744.1 - 2.9e-05 23.0 0.9 0.04 12.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM88744.1 - 0.00053 19.9 0.3 0.0014 18.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM88744.1 - 0.0038 16.1 0.2 0.0058 15.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EIM88744.1 - 0.026 13.4 0.7 0.049 12.5 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM88744.1 - 0.093 11.1 0.5 0.39 9.1 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIM88744.1 - 0.097 12.7 0.3 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cu-oxidase PF00394.17 EIM88745.1 - 2.6e-43 147.6 1.9 1.6e-38 132.1 0.0 2.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM88745.1 - 7.7e-38 128.8 0.9 3.3e-36 123.5 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM88745.1 - 6.6e-35 119.6 8.9 2.5e-33 114.4 0.7 4.0 3 1 0 3 3 3 2 Multicopper oxidase SWM_repeat PF13753.1 EIM88745.1 - 0.0089 15.1 0.4 0.0089 15.1 0.3 1.8 2 0 0 2 2 2 1 Putative flagellar system-associated repeat Aldo_ket_red PF00248.16 EIM88746.1 - 7.3e-28 97.1 0.0 8.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C13 PF01650.13 EIM88747.1 - 7.9e-45 153.1 0.1 1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Melibiase PF02065.13 EIM88748.1 - 2.3e-20 72.6 0.6 3.6e-17 62.1 0.1 2.2 2 0 0 2 2 2 2 Melibiase FAD_binding_3 PF01494.14 EIM88749.1 - 1.3e-08 34.2 0.0 2.4e-07 30.1 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM88749.1 - 4.4e-08 32.4 0.1 2.6e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM88749.1 - 4.6e-08 32.9 0.3 1.5e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM88749.1 - 1.5e-06 28.5 0.0 0.0014 18.9 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM88749.1 - 2.2e-05 23.4 0.3 3.9e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIM88749.1 - 0.00076 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EIM88749.1 - 0.0038 16.3 0.8 0.018 14.1 0.3 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EIM88749.1 - 0.0051 15.9 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM88749.1 - 0.015 15.1 0.1 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM88749.1 - 0.029 12.8 0.0 0.048 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EIM88749.1 - 0.03 13.2 0.1 0.17 10.7 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EIM88749.1 - 0.033 13.0 0.1 0.057 12.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIM88749.1 - 0.085 12.5 0.1 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIM88749.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_6 PF12697.2 EIM88750.1 - 1.5e-25 90.4 0.0 2.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88750.1 - 7e-12 45.4 0.0 2.8e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM88750.1 - 1.4e-11 44.3 0.0 3.4e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM88750.1 - 0.00016 20.9 0.0 0.024 13.8 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EIM88750.1 - 0.0025 17.6 0.0 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EIM88750.1 - 0.012 14.9 0.0 5.9 6.1 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 EIM88750.1 - 0.014 15.1 0.0 2.5 7.7 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EIM88750.1 - 0.062 12.8 0.7 1.4 8.4 0.5 2.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold zf-RVT PF13966.1 EIM88751.1 - 9.6e-07 29.0 0.9 2.9e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase F-box-like PF12937.2 EIM88752.1 - 2e-09 37.0 0.3 4.8e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88752.1 - 0.022 14.3 2.0 0.048 13.3 0.1 2.5 2 0 0 2 2 2 0 F-box domain p450 PF00067.17 EIM88754.1 - 5.9e-50 170.1 0.7 1.4e-26 93.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bud13 PF09736.4 EIM88755.1 - 3.9e-46 156.9 13.6 3.9e-46 156.9 9.4 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Aminotran_1_2 PF00155.16 EIM88756.1 - 8.1e-27 94.1 0.0 9.1e-22 77.4 0.0 2.3 2 1 0 2 2 2 2 Aminotransferase class I and II RNA_pol_L_2 PF13656.1 EIM88759.1 - 1.4e-26 91.6 0.0 1.7e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIM88759.1 - 1.9e-07 30.1 0.0 2.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPc PF00782.15 EIM88761.1 - 9.8e-29 99.6 0.0 1.5e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM88761.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIM88761.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Abhydrolase_6 PF12697.2 EIM88763.1 - 8.3e-09 35.6 0.0 3.3e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 EIM88764.1 - 6.9e-32 110.2 0.2 1.1e-15 57.4 0.0 3.3 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM88764.1 - 2.2e-24 85.1 0.0 4.5e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 EIM88767.1 - 2.4e-41 141.6 36.1 2.4e-41 141.6 25.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88767.1 - 1.4e-13 50.2 25.4 2e-12 46.4 17.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.11 EIM88767.1 - 0.00058 18.6 0.3 0.00095 17.9 0.2 1.3 1 0 0 1 1 1 1 BT1 family MFS_3 PF05977.8 EIM88767.1 - 0.001 17.2 3.2 0.002 16.3 2.2 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Het-C PF07217.6 EIM88768.1 - 4.6e-220 731.9 0.0 5.6e-220 731.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C MutS_III PF05192.13 EIM88768.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 MutS domain III BTB PF00651.26 EIM88769.1 - 4e-07 30.0 0.1 1.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain NADH_4Fe-4S PF10589.4 EIM88769.1 - 0.0079 15.3 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region GTP_EFTU PF00009.22 EIM88770.1 - 2.3e-49 167.4 0.0 3.5e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIM88770.1 - 1.8e-18 66.1 0.0 4.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIM88770.1 - 1.5e-05 24.9 1.8 3.5e-05 23.8 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM88770.1 - 6.5e-05 22.8 0.2 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIM88770.1 - 0.00071 20.0 0.0 0.011 16.2 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIM88770.1 - 0.0032 16.6 0.3 1 8.5 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Sugar_tr PF00083.19 EIM88771.1 - 1.7e-85 287.2 20.8 2.1e-85 287.0 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM88771.1 - 5.1e-17 61.6 41.8 6e-11 41.6 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 EIM88772.1 - 4.3e-11 42.7 0.1 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Cu-oxidase PF00394.17 EIM88774.1 - 2.4e-49 167.2 0.4 2.3e-46 157.5 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM88774.1 - 1.2e-38 131.7 4.3 7.3e-35 119.4 0.0 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM88774.1 - 1e-36 125.2 5.3 5.3e-34 116.4 0.1 3.6 3 1 0 3 3 3 3 Multicopper oxidase BTB PF00651.26 EIM88776.1 - 2.3e-10 40.4 0.1 6.1e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIM88777.1 - 1.1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain PDEase_I PF00233.14 EIM88778.1 - 6.6e-40 137.3 1.1 2.5e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIM88778.1 - 0.017 15.1 0.3 0.065 13.2 0.2 2.0 1 1 0 1 1 1 0 HD domain BTB PF00651.26 EIM88779.1 - 1.1e-20 73.7 0.0 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.10 EIM88779.1 - 0.049 13.7 0.1 5.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Inhibitor_I78 PF11720.3 EIM88780.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Methyltransf_16 PF10294.4 EIM88781.1 - 5.3e-11 42.2 0.0 7.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase BTB PF00651.26 EIM88783.1 - 5.5e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Sec23_trunk PF04811.10 EIM88784.1 - 1.5e-56 191.5 0.0 2e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIM88784.1 - 9.5e-19 66.7 0.2 1.6e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIM88784.1 - 4.3e-14 51.7 2.1 1.1e-13 50.5 1.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIM88784.1 - 6.3e-14 52.2 0.0 1.4e-11 44.7 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIM88784.1 - 2.2e-05 24.0 0.0 4.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Mcp5_PH PF12814.2 EIM88785.1 - 9.5e-42 141.8 0.0 1.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 EIM88785.1 - 0.024 14.8 0.1 0.063 13.4 0.0 1.8 2 0 0 2 2 2 0 PH domain V_ATPase_I PF01496.14 EIM88785.1 - 3.3 5.4 9.1 7.4 4.2 6.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin_2 PF14523.1 EIM88785.1 - 7 6.7 15.9 2.7 8.0 7.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein NTF2 PF02136.15 EIM88786.1 - 9.6e-27 93.7 0.1 1.5e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EIM88786.1 - 5e-09 35.6 0.0 8.8e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88786.1 - 7.5e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88786.1 - 0.022 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 EIM88787.1 - 3.8e-09 36.4 0.0 6.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIM88788.1 - 4e-09 36.4 0.1 3e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain RRM_1 PF00076.17 EIM88788.1 - 8.1e-08 31.7 0.1 2e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88788.1 - 1e-07 31.6 0.0 3.2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88788.1 - 7.8e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM88788.1 - 0.064 13.1 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif BTB PF00651.26 EIM88789.1 - 1.8e-10 40.7 0.0 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 EIM88790.1 - 4.4e-69 232.5 0.0 5.3e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88790.1 - 2.6e-27 95.5 0.0 3.9e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM88790.1 - 1.5e-06 27.3 0.0 2.4e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM88790.1 - 0.00059 19.2 0.0 0.002 17.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EIM88790.1 - 0.0045 16.0 0.3 0.012 14.6 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM88790.1 - 0.0053 16.5 0.4 0.096 12.3 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 EIM88790.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Ureidogly_hydro PF04115.7 EIM88793.1 - 0.022 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Ureidoglycolate hydrolase Rad52_Rad22 PF04098.10 EIM88794.1 - 5.3e-55 185.3 0.0 6.2e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MFS_1 PF07690.11 EIM88795.1 - 9.1e-29 100.2 27.4 1.3e-28 99.7 18.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 EIM88796.1 - 6.5e-75 251.8 0.0 2.7e-74 249.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM88796.1 - 6.4e-57 192.6 0.7 4.7e-56 189.8 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM88796.1 - 4.5e-23 80.9 0.1 8.2e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EIM88797.1 - 4.3e-75 252.4 0.0 1.2e-74 251.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM88797.1 - 4.6e-58 196.4 2.0 9.5e-57 192.1 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM88797.1 - 5.1e-23 80.8 0.0 9e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PhaG_MnhG_YufB PF03334.9 EIM88798.1 - 0.024 14.6 0.3 0.03 14.3 0.2 1.2 1 1 0 1 1 1 0 Na+/H+ antiporter subunit VPEP PF07589.6 EIM88798.1 - 2.8 7.9 6.3 13 5.8 0.1 3.0 3 0 0 3 3 3 0 PEP-CTERM motif Cu-oxidase PF00394.17 EIM88799.1 - 1.9e-49 167.6 0.4 8.6e-47 158.9 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM88799.1 - 9.4e-39 132.0 2.6 2e-34 118.0 0.0 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM88799.1 - 1e-36 125.2 4.3 6.1e-35 119.5 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Sterol_MT_C PF08498.5 EIM88800.1 - 1.8e-23 82.2 0.1 2.6e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EIM88800.1 - 3e-18 65.8 0.0 4.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88800.1 - 6.1e-17 61.8 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIM88800.1 - 1.7e-14 53.5 0.0 2.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EIM88800.1 - 6.3e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM88800.1 - 1.7e-12 47.3 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM88800.1 - 2.2e-12 47.2 0.1 5.9e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88800.1 - 7.5e-11 42.0 0.0 1.7e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM88800.1 - 2.4e-10 40.6 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM88800.1 - 1e-07 31.3 0.0 1.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIM88800.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EIM88800.1 - 2.3e-05 24.0 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EIM88800.1 - 0.00044 19.8 0.1 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EIM88800.1 - 0.00044 19.8 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 EIM88800.1 - 0.00053 19.1 0.0 0.00079 18.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIM88800.1 - 0.0059 17.4 0.0 0.019 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIM88800.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 EIM88800.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EIM88800.1 - 0.037 13.0 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EIM88800.1 - 0.044 12.9 0.1 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 EIM88800.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mob_Pre PF01076.14 EIM88800.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme WD40 PF00400.27 EIM88802.1 - 8.7e-45 149.0 21.7 1.1e-07 31.4 0.1 11.4 11 1 1 12 12 12 9 WD domain, G-beta repeat IKI3 PF04762.7 EIM88802.1 - 2.1e-05 22.6 0.0 0.0019 16.1 0.0 2.4 2 1 0 2 2 2 2 IKI3 family PQQ_3 PF13570.1 EIM88802.1 - 0.0002 21.5 10.2 0.82 10.0 0.1 6.7 8 0 0 8 8 8 2 PQQ-like domain CPSF_A PF03178.10 EIM88802.1 - 0.022 13.8 0.0 0.077 12.0 0.0 1.9 1 1 0 1 1 1 0 CPSF A subunit region DUF3312 PF11768.3 EIM88802.1 - 0.089 11.0 0.0 10 4.2 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3312) Mad3_BUB1_I PF08311.7 EIM88803.1 - 3.8e-28 97.7 0.2 6e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 p450 PF00067.17 EIM88804.1 - 1.3e-62 211.8 0.0 1.7e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chordopox_A15 PF05846.7 EIM88805.1 - 0.0035 17.3 0.3 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Chordopoxvirus A15 protein Lig_chan PF00060.21 EIM88805.1 - 0.19 11.4 2.0 0.45 10.2 1.4 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel RRM_1 PF00076.17 EIM88806.1 - 1.6e-32 110.8 0.0 4.3e-16 58.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88806.1 - 1.8e-18 66.2 0.0 1.5e-11 44.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88806.1 - 9.7e-12 44.5 0.0 1.3e-07 31.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIM88806.1 - 0.007 16.0 0.3 1.2 8.8 0.1 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EIM88806.1 - 0.03 14.0 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM PF05172.8 EIM88806.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.21 EIM88807.1 - 0.00022 21.3 1.9 0.00078 19.6 1.3 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM88807.1 - 0.05 13.9 0.6 0.13 12.6 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger RRM_1 PF00076.17 EIM88808.1 - 3.7e-12 45.6 0.0 5.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88808.1 - 3.5e-09 36.5 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIM88808.1 - 2.8e-07 30.8 0.5 6.9e-07 29.6 0.3 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EIM88808.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_anti-codon PF01336.20 EIM88809.1 - 3.7e-06 26.6 0.2 1.2e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.4 EIM88809.1 - 0.00018 20.4 0.3 0.23 10.2 0.0 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DUF1618 PF07762.9 EIM88810.1 - 0.079 13.1 0.1 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1618) Dioxygenase_C PF00775.16 EIM88812.1 - 6.5e-09 35.3 0.1 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase Abhydrolase_6 PF12697.2 EIM88817.1 - 1.1e-28 100.7 1.4 2.3e-27 96.3 1.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM88817.1 - 4.5e-14 52.5 0.0 2.4e-13 50.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM88817.1 - 3.3e-07 30.1 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM88817.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Putative lysophospholipase p450 PF00067.17 EIM88819.1 - 9e-60 202.4 0.0 2.1e-59 201.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UPF0029 PF01205.14 EIM88821.1 - 4.4e-24 84.2 0.0 5.7e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Hamartin PF04388.7 EIM88821.1 - 0.32 9.6 3.0 0.36 9.4 2.1 1.0 1 0 0 1 1 1 0 Hamartin protein Sporozoite_P67 PF05642.6 EIM88824.1 - 0.047 11.5 2.2 0.03 12.2 0.3 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sec2p PF06428.6 EIM88826.1 - 1.3e-13 50.6 11.9 1.3e-13 50.6 8.3 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p NUMOD1 PF07453.8 EIM88826.1 - 0.0027 17.4 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 NUMOD1 domain Herpes_UL6 PF01763.11 EIM88826.1 - 0.62 8.1 5.3 0.18 9.9 0.8 1.7 1 1 0 2 2 2 0 Herpesvirus UL6 like Gon7 PF08738.5 EIM88826.1 - 3.8 7.5 11.2 0.24 11.4 1.6 3.0 1 1 0 2 2 2 0 Gon7 family FlxA PF14282.1 EIM88826.1 - 6.9 6.6 13.3 0.83 9.6 0.1 3.6 3 0 0 3 3 3 0 FlxA-like protein TPR_10 PF13374.1 EIM88827.1 - 0.29 11.1 2.1 0.57 10.1 1.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2884 PF11101.3 EIM88828.1 - 0.0023 17.3 3.5 0.028 13.7 0.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2884) KID PF02524.9 EIM88828.1 - 0.25 11.5 2.5 3e+02 2.3 0.0 5.0 5 0 0 5 5 5 0 KID repeat DUF883 PF05957.8 EIM88828.1 - 0.7 10.3 8.6 20 5.6 0.5 4.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EIM88828.1 - 1.1 9.6 11.8 7.6e+03 -2.7 8.2 4.4 1 1 0 1 1 1 0 YtxH-like protein Dodecin PF07311.7 EIM88828.1 - 6.6 6.8 11.0 48 4.0 0.0 5.5 6 1 0 6 6 6 0 Dodecin p450 PF00067.17 EIM88830.1 - 8.6e-54 182.7 0.0 1.7e-53 181.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.16 EIM88832.1 - 1e-53 181.3 0.0 1.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIM88832.1 - 1e-16 60.6 0.0 4.5e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIM88832.1 - 0.041 13.9 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain F_actin_bind PF08919.5 EIM88832.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 F-actin binding EI24 PF07264.6 EIM88834.1 - 0.00061 19.2 11.5 0.0058 16.0 7.8 2.5 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) KAR9 PF08580.5 EIM88835.1 - 4.9 5.2 10.8 5.3 5.1 7.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DFP PF04127.10 EIM88836.1 - 2.6e-20 72.8 0.0 2.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF3129 PF11327.3 EIM88837.1 - 1.9e-06 27.8 10.0 2.4e-06 27.4 6.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3129) RRM_1 PF00076.17 EIM88839.1 - 1.2e-21 76.1 0.0 2.1e-10 40.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88839.1 - 3.6e-18 65.1 0.0 2.1e-07 30.6 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88839.1 - 3e-17 62.3 0.0 4.5e-09 36.1 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RdRP PF05183.7 EIM88841.1 - 1.3e-134 450.0 0.0 1.7e-134 449.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase 5-FTHF_cyc-lig PF01812.15 EIM88842.1 - 6.3e-39 133.6 0.0 7.2e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PIG-P PF08510.7 EIM88843.1 - 2.4e-27 95.0 0.3 3e-27 94.7 0.2 1.1 1 0 0 1 1 1 1 PIG-P SieB PF14163.1 EIM88843.1 - 0.45 10.0 1.9 0.62 9.6 1.3 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DPM2 PF07297.7 EIM88843.1 - 0.91 9.8 7.3 1.9 8.8 5.0 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-H2C2_2 PF13465.1 EIM88844.1 - 1.1e-06 28.6 12.4 2.3e-05 24.4 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM88844.1 - 2.1e-05 24.5 5.6 0.064 13.6 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM88844.1 - 2.4e-05 24.3 15.1 0.001 19.3 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIM88844.1 - 0.045 13.9 2.9 1.7 8.8 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPG_N PF00752.12 EIM88845.1 - 1.5e-25 89.4 0.0 4e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EIM88845.1 - 1.6e-25 88.9 0.0 2.9e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIM88845.1 - 1.7e-07 31.0 0.0 3.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EIM88845.1 - 0.00051 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 EIM88845.1 - 0.0032 17.2 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM88845.1 - 0.007 15.9 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM88845.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EIM88845.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_75 PF07335.6 EIM88845.1 - 0.097 12.5 0.0 0.64 9.8 0.0 1.9 1 1 1 2 2 2 0 Fungal chitosanase of glycosyl hydrolase group 75 TPR_9 PF13371.1 EIM88845.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.16 EIM88846.1 - 1.8e-38 131.6 7.1 3.1e-38 130.9 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EIM88846.1 - 0.0044 16.9 14.1 0.012 15.6 9.8 1.7 1 0 0 1 1 1 1 Chitin recognition protein MutS_V PF00488.16 EIM88849.1 - 1.1e-73 247.5 0.0 1.8e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIM88849.1 - 1.7e-43 148.8 0.9 3.2e-43 147.9 0.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIM88849.1 - 1.1e-33 115.6 0.1 2.2e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EIM88849.1 - 5e-09 36.3 0.0 2.8e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EIM88849.1 - 3.2e-07 30.4 0.1 8.9e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MFS_1 PF07690.11 EIM88851.1 - 1.3e-23 83.3 34.8 7.1e-19 67.7 8.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM88851.1 - 0.00075 18.1 9.8 0.00075 18.1 6.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EIM88851.1 - 0.074 12.8 0.2 0.074 12.8 0.1 2.1 2 0 0 2 2 2 0 MFS_1 like family CENP-B_dimeris PF09026.5 EIM88851.1 - 0.11 12.6 11.0 0.24 11.6 7.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EIM88851.1 - 1.5 6.6 5.7 2 6.2 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EIM88851.1 - 5.8 4.6 21.1 0.0028 15.6 5.7 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen F-box PF00646.28 EIM88852.1 - 0.099 12.3 0.6 0.24 11.1 0.4 1.7 1 0 0 1 1 1 0 F-box domain DUF667 PF05018.8 EIM88854.1 - 1.7e-13 50.2 0.0 0.002 17.3 0.0 4.1 3 1 0 3 3 3 3 Protein of unknown function (DUF667) HAD_2 PF13419.1 EIM88855.1 - 2.1e-30 106.2 0.1 2.8e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM88855.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EIM88855.1 - 0.013 15.0 0.3 0.28 10.7 0.2 2.2 1 1 0 1 1 1 0 Acid Phosphatase Methyltransf_16 PF10294.4 EIM88856.1 - 6e-13 48.6 0.0 9.9e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM88856.1 - 0.00025 21.6 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM88856.1 - 0.039 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FSIP1 PF15554.1 EIM88858.1 - 0.55 8.9 3.1 0.67 8.7 2.2 1.1 1 0 0 1 1 1 0 FSIP1 family RRM_1 PF00076.17 EIM88859.1 - 2.9e-31 106.8 0.0 1.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88859.1 - 2.7e-23 81.7 0.0 5.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM88859.1 - 1.3e-05 24.9 0.0 0.0052 16.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 EIM88859.1 - 0.0073 16.3 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family F-box-like PF12937.2 EIM88860.1 - 3.3e-12 45.9 1.3 8.7e-12 44.5 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88860.1 - 0.5 10.0 4.0 10 5.8 0.9 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EIM88861.1 - 3.6e-08 33.0 0.3 1.1e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM88861.1 - 0.015 14.9 5.4 1.5 8.5 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM88861.1 - 0.45 10.3 9.6 51 3.7 0.1 5.3 5 1 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 EIM88861.1 - 8 6.2 8.3 9.1 6.0 0.8 3.4 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EIM88862.1 - 3.2e-09 36.3 0.1 1.1e-08 34.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM88862.1 - 0.0053 16.3 0.0 0.69 9.5 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Metallophos PF00149.23 EIM88863.1 - 2.7e-44 150.9 0.1 3.4e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EIM88864.1 - 7.2e-52 171.5 24.1 5.5e-13 48.2 0.1 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 EIM88864.1 - 1e-16 60.7 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EIM88864.1 - 1.7e-05 24.6 1.6 0.33 10.6 0.0 5.1 3 2 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIM88864.1 - 0.001 17.4 0.3 0.69 8.1 0.0 3.5 4 0 0 4 4 4 1 Cytochrome D1 heme domain IKI3 PF04762.7 EIM88864.1 - 0.0027 15.6 0.0 0.81 7.4 0.0 2.7 2 1 0 3 3 3 2 IKI3 family DUF1513 PF07433.6 EIM88864.1 - 0.046 12.6 1.2 1.2 7.9 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.1 EIM88864.1 - 0.11 11.4 0.0 4.9 6.0 0.0 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus E1-E2_ATPase PF00122.15 EIM88866.1 - 8.6e-50 168.9 5.4 8.6e-50 168.9 3.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIM88866.1 - 1.8e-23 84.0 0.3 6e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM88866.1 - 9.1e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIM88866.1 - 1.4e-08 34.6 0.1 4.1e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EIM88866.1 - 7.5e-05 22.4 1.1 0.002 17.7 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4038 PF13204.1 EIM88867.1 - 1.2e-54 185.6 0.4 3.1e-53 180.9 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.2 EIM88867.1 - 3.4e-09 36.3 0.0 9e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase MFS_1 PF07690.11 EIM88868.1 - 3.1e-28 98.5 34.9 4.1e-28 98.1 24.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.13 EIM88869.1 - 1.3e-08 34.6 0.1 2e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Kelch_4 PF13418.1 EIM88870.1 - 6e-30 102.7 7.9 1.2e-06 28.1 0.0 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EIM88870.1 - 1.8e-26 91.6 13.6 3.9e-07 30.0 0.0 7.1 8 1 0 8 8 8 4 Galactose oxidase, central domain DUF4110 PF13422.1 EIM88870.1 - 1.8e-20 72.5 0.0 1.8e-20 72.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 EIM88870.1 - 1.3e-18 66.2 8.2 1.2e-05 25.2 0.0 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 EIM88870.1 - 4.5e-17 61.3 7.0 2.6e-06 26.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EIM88870.1 - 3.9e-16 58.6 11.4 9.6e-06 25.4 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EIM88870.1 - 1.2e-08 34.4 16.3 0.0086 15.8 0.8 5.5 5 2 0 5 5 5 3 Kelch motif Pkinase PF00069.20 EIM88873.1 - 1.2e-35 122.9 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM88873.1 - 7.1e-11 41.6 0.0 4.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIM88873.1 - 0.0025 17.5 1.7 0.0031 17.2 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM88873.1 - 0.1 11.5 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EIM88873.1 - 0.12 11.3 0.0 0.35 9.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF904 PF06005.7 EIM88873.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) MIP-T3 PF10243.4 EIM88873.1 - 7 4.9 18.7 14 4.0 13.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 F-box-like PF12937.2 EIM88875.1 - 1.1e-07 31.4 1.1 3e-07 30.0 0.8 1.9 1 0 0 1 1 1 1 F-box-like Hs1pro-1_C PF07014.7 EIM88875.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus MgtE PF01769.11 EIM88877.1 - 0.21 11.8 5.5 0.39 11.0 1.3 2.6 2 0 0 2 2 2 0 Divalent cation transporter Bac_rhodopsin PF01036.13 EIM88878.1 - 3.9e-47 160.4 18.3 4.8e-47 160.1 12.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein F-box-like PF12937.2 EIM88881.1 - 1.4e-08 34.3 2.1 1.4e-08 34.3 1.5 2.3 2 0 0 2 2 2 1 F-box-like SipA PF09052.5 EIM88882.1 - 0.0037 15.7 0.0 0.0047 15.3 0.0 1.0 1 0 0 1 1 1 1 Salmonella invasion protein A DUF1192 PF06698.6 EIM88882.1 - 0.047 13.5 1.0 0.088 12.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1191 PF06697.7 EIM88882.1 - 0.055 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 EIM88882.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 bZIP_2 PF07716.10 EIM88882.1 - 0.062 13.1 1.1 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper CCDC14 PF15254.1 EIM88882.1 - 0.083 11.2 0.8 0.11 10.8 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 SKG6 PF08693.5 EIM88882.1 - 0.13 11.6 0.6 0.25 10.6 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4391 PF14335.1 EIM88882.1 - 0.14 11.5 0.1 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) ERG2_Sigma1R PF04622.7 EIM88883.1 - 4.8e-83 277.6 0.1 6.2e-83 277.3 0.1 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERG2_Sigma1R PF04622.7 EIM88884.1 - 4.6e-73 245.0 0.4 1.1e-71 240.5 0.3 2.0 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Herpes_teg_N PF04843.7 EIM88884.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Histone PF00125.19 EIM88885.1 - 4e-22 78.1 0.3 6.1e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM88885.1 - 3.3e-06 27.0 0.1 3.3e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIM88885.1 - 0.00039 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EIM88885.1 - 0.02 15.3 0.6 0.028 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 EIM88885.1 - 0.075 12.4 0.1 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Herpes_BLLF1 PF05109.8 EIM88885.1 - 0.89 7.4 7.0 1.1 7.1 4.9 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Histone PF00125.19 EIM88886.1 - 2.8e-26 91.4 0.0 3.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM88886.1 - 3.7e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Big_3_4 PF13754.1 EIM88887.1 - 0.3 11.4 4.9 0.26 11.6 1.4 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) PWI PF01480.12 EIM88888.1 - 7.5e-28 96.4 0.0 1.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 PWI domain F-box-like PF12937.2 EIM88890.1 - 4.8e-08 32.6 2.6 5.8e-08 32.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM88890.1 - 0.013 15.1 0.1 0.79 9.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) MR_MLE_C PF13378.1 EIM88892.1 - 1.1e-28 99.4 0.0 1.9e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EIM88892.1 - 2.1e-19 69.6 0.0 7.3e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EIM88892.1 - 9.3e-08 32.4 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Amidohydro_2 PF04909.9 EIM88892.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase EMP24_GP25L PF01105.19 EIM88893.1 - 1.4e-37 129.1 0.0 1.6e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD F-box-like PF12937.2 EIM88894.1 - 5.8e-07 29.1 0.8 2.3e-06 27.2 0.6 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88894.1 - 0.00043 19.8 0.1 0.0015 18.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.6 EIM88894.1 - 4.4 5.0 5.2 5.7 4.6 3.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.2 EIM88895.1 - 3.1e-09 36.4 3.0 5.8e-09 35.5 2.1 1.5 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.22 EIM88897.1 - 1.5e-47 161.3 0.0 5.5e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM88897.1 - 1.4e-31 109.9 31.2 4.7e-17 62.2 2.6 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM88897.1 - 1.5e-09 37.4 0.0 0.004 16.4 0.3 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM88897.1 - 9.1e-07 28.4 0.0 0.0091 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EIM88897.1 - 1.3e-05 25.3 0.9 0.47 10.3 0.0 3.8 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 EIM88897.1 - 0.00091 19.2 0.1 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIM88897.1 - 0.00095 19.3 0.9 1.9 8.6 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIM88897.1 - 0.0017 17.8 0.3 0.46 9.8 0.0 2.8 2 1 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 EIM88897.1 - 0.0019 17.6 1.3 0.16 11.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EIM88897.1 - 0.0034 16.3 0.0 0.95 8.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EIM88897.1 - 0.021 14.3 0.1 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EIM88897.1 - 0.03 13.4 1.1 3.8 6.5 0.0 2.7 3 0 0 3 3 3 0 KaiC DUF87 PF01935.12 EIM88897.1 - 0.033 13.9 0.3 0.083 12.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 EIM88897.1 - 0.12 12.8 0.5 27 5.3 0.1 3.0 3 0 0 3 3 2 0 Miro-like protein NB-ARC PF00931.17 EIM88897.1 - 0.12 11.2 0.1 3.3 6.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain DUF258 PF03193.11 EIM88897.1 - 0.13 11.4 0.1 7.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 EIM88897.1 - 0.13 11.1 1.1 5.6 5.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EIM88897.1 - 0.32 11.2 2.6 7.4 6.8 0.1 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EIM88897.1 - 1.3 8.4 3.6 1.7 8.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sugar_tr PF00083.19 EIM88898.1 - 4.7e-92 308.9 23.5 5.7e-92 308.6 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM88898.1 - 4.8e-26 91.2 44.0 6.3e-21 74.4 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EIM88898.1 - 0.04 13.4 0.4 0.09 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Dus PF01207.12 EIM88899.1 - 5.1e-53 179.9 0.0 5.8e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EIM88899.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EIM88899.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.20 EIM88899.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.16 EIM88899.1 - 0.1 11.6 0.1 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 EIM88899.1 - 0.13 11.1 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Aldo_ket_red PF00248.16 EIM88900.1 - 3.9e-67 226.0 0.0 4.4e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM88901.1 - 2.9e-66 223.2 0.0 3.3e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2 PF00096.21 EIM88902.1 - 2.3e-09 37.0 17.6 0.00017 21.6 0.3 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM88902.1 - 5.6e-06 26.3 12.3 0.032 14.5 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIM88902.1 - 0.05 13.7 0.6 0.2 11.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIM88902.1 - 0.18 11.9 4.4 0.47 10.5 3.1 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIM88902.1 - 1.2 9.4 5.8 1.5 9.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIM88902.1 - 1.6 9.0 7.1 0.35 11.1 0.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain SPC25 PF06703.6 EIM88903.1 - 6.3e-36 123.3 0.0 4e-35 120.7 0.0 1.9 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) NAD_binding_8 PF13450.1 EIM88904.1 - 2e-11 43.7 0.0 4.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIM88904.1 - 8.6e-08 31.6 0.0 1.4e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EIM88904.1 - 1.8e-07 30.4 0.0 3.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM88904.1 - 0.00032 20.4 0.4 0.0013 18.5 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM88904.1 - 0.0041 16.0 0.0 0.0078 15.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM88904.1 - 0.0045 16.1 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM88904.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM88904.1 - 0.0084 16.0 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM88904.1 - 0.011 16.1 0.1 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM88904.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIM88904.1 - 0.02 13.5 0.0 0.02 13.5 0.0 1.8 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EIM88904.1 - 0.028 12.9 0.0 0.053 11.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIM88904.1 - 0.079 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HMG_CoA_synt_N PF01154.12 EIM88905.1 - 1.4e-81 272.2 0.0 1.9e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EIM88905.1 - 1e-79 267.9 0.7 1.9e-79 267.1 0.5 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Terpene_synth_C PF03936.11 EIM88906.1 - 8.6e-08 31.7 1.1 1.3e-07 31.1 0.8 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Glycos_trans_3N PF02885.12 EIM88906.1 - 0.17 11.5 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain EthD PF07110.6 EIM88907.1 - 4.2e-14 53.2 0.1 5.7e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 EIM88908.1 - 8.7e-79 265.1 0.0 9.7e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EIM88909.1 - 2.5e-31 108.7 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM88909.1 - 2.7e-08 34.0 0.0 5e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM88909.1 - 0.0018 17.0 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIM88909.1 - 0.039 12.9 0.2 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EIM88909.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 EIM88910.1 - 1.6e-75 254.4 0.0 2e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM88911.1 - 2.4e-72 243.9 0.0 3e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM88912.1 - 4e-68 230.0 0.0 4.9e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EIM88913.1 - 1.2e-16 60.4 1.2 5.6e-16 58.2 0.3 2.3 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EIM88913.1 - 2.6e-07 30.4 0.4 5.4e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EIM88913.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.11 EIM88914.1 - 9.1e-35 119.9 76.4 9.4e-33 113.3 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EIM88915.1 - 6.6e-30 104.2 0.3 9.5e-30 103.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM88915.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM88915.1 - 5.5e-12 45.9 0.1 7.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM88915.1 - 2.9e-05 23.6 0.2 6.6e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIM88915.1 - 9.2e-05 21.4 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIM88915.1 - 0.0069 16.4 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIM88915.1 - 0.011 15.4 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EIM88915.1 - 0.06 12.9 0.3 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ubiquitin PF00240.18 EIM88917.1 - 1.3e-24 85.3 0.1 2.2e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIM88917.1 - 2.2e-11 43.2 0.7 2.2e-10 40.0 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM88917.1 - 0.025 14.8 0.0 0.098 12.9 0.0 1.9 2 1 0 2 2 2 0 Ubiquitin-like domain zf-RING_5 PF14634.1 EIM88917.1 - 0.038 13.7 8.1 0.096 12.4 5.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM88917.1 - 1.8 8.6 8.9 4.4 7.4 6.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM88917.1 - 6.6 6.4 8.0 15 5.3 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cu_amine_oxid PF01179.15 EIM88918.1 - 2.5e-101 339.4 0.0 3.1e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EIM88918.1 - 1.1e-05 25.2 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) PCI PF01399.22 EIM88919.1 - 1.2e-22 80.2 0.0 4.1e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.6 EIM88919.1 - 1.2e-17 64.0 0.3 1.2e-17 64.0 0.2 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EIM88919.1 - 0.033 14.1 0.1 0.13 12.2 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.15 EIM88919.1 - 0.22 11.2 2.5 0.7 9.6 1.7 1.9 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 p450 PF00067.17 EIM88920.1 - 7.6e-69 232.4 0.0 2.2e-68 230.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 PHD PF00628.24 EIM88921.1 - 3.3e-07 29.8 3.7 7.5e-07 28.7 2.6 1.5 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 EIM88921.1 - 0.0029 17.2 6.2 0.012 15.2 4.3 2.1 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.1 EIM88921.1 - 0.018 14.3 0.8 0.037 13.3 0.6 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EIM88921.1 - 0.38 10.1 4.6 0.76 9.1 3.2 1.5 1 0 0 1 1 1 0 PHD-finger Ribophorin_II PF05817.9 EIM88923.1 - 1.7e-22 79.4 0.0 2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.15 EIM88924.1 - 5.3e-117 391.2 0.0 6.2e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF285 PF03382.9 EIM88924.1 - 0.017 14.7 0.6 0.091 12.3 0.4 2.0 2 1 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 F-box-like PF12937.2 EIM88925.1 - 0.00037 20.1 0.2 0.00083 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM88925.1 - 0.069 12.8 0.1 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain Gin PF10764.4 EIM88925.1 - 0.087 12.5 2.8 26 4.6 0.0 4.1 4 0 0 4 4 4 0 Inhibitor of sigma-G Gin Sec20 PF03908.8 EIM88926.1 - 7.3e-17 60.8 1.6 7.3e-17 60.8 1.1 2.4 2 0 0 2 2 2 1 Sec20 Spt20 PF12090.3 EIM88927.1 - 1.7e-33 115.4 0.0 1.7e-33 115.4 0.0 4.9 3 1 0 3 3 3 1 Spt20 family SEP PF08059.8 EIM88927.1 - 0.0052 17.0 0.4 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 SEP domain Mem_trans PF03547.13 EIM88928.1 - 2.3e-42 144.6 0.1 9.2e-36 122.9 0.0 2.2 2 1 0 2 2 2 2 Membrane transport protein zf-C3HC4_3 PF13920.1 EIM88929.1 - 6.4e-13 48.1 5.8 6.4e-13 48.1 4.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EIM88929.1 - 6.3e-09 35.6 5.6 6.3e-09 35.6 3.9 2.7 2 1 0 2 2 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 EIM88929.1 - 5.9e-07 29.3 6.9 5.9e-07 29.3 4.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM88929.1 - 6.1e-06 25.9 5.4 6.1e-06 25.9 3.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIM88929.1 - 4.6e-05 23.0 6.0 4.6e-05 23.0 4.2 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EIM88929.1 - 7.1e-05 22.6 3.3 7.1e-05 22.6 2.3 3.3 3 0 0 3 3 2 1 FYVE-type zinc finger Peptidase_S30 PF01577.11 EIM88929.1 - 0.0018 17.6 2.9 0.0029 17.0 2.0 1.2 1 0 0 1 1 1 1 Potyvirus P1 protease Prok-RING_4 PF14447.1 EIM88929.1 - 0.013 15.0 1.9 0.013 15.0 1.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Armet PF10208.4 EIM88929.1 - 0.013 15.1 0.1 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding SAP PF02037.22 EIM88929.1 - 0.015 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain zf-P11 PF03854.9 EIM88929.1 - 0.015 14.7 1.8 0.015 14.7 1.3 2.7 2 0 0 2 2 2 0 P-11 zinc finger SAPS PF04499.10 EIM88929.1 - 0.047 12.3 1.5 0.059 12.0 1.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0547 PF10571.4 EIM88929.1 - 0.056 13.1 9.0 0.53 10.0 0.4 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF1777 PF08648.7 EIM88929.1 - 0.15 11.7 19.3 0.29 10.8 13.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) zf-RING_5 PF14634.1 EIM88929.1 - 0.35 10.6 23.2 0.043 13.5 3.8 2.5 2 0 0 2 2 2 0 zinc-RING finger domain HypA PF01155.14 EIM88929.1 - 7.3 6.3 13.3 0.39 10.4 2.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PBP_sp32 PF07222.7 EIM88929.1 - 9.7 5.2 14.0 19 4.3 9.7 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ADH_N PF08240.7 EIM88931.1 - 4.1e-30 103.7 3.8 6.9e-30 103.0 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM88931.1 - 1.1e-26 92.9 0.9 1.7e-26 92.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM88931.1 - 0.0054 17.6 0.2 0.0095 16.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CHAP PF05257.11 EIM88931.1 - 0.059 13.0 0.6 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 CHAP domain Zn_clus PF00172.13 EIM88932.1 - 0.0025 17.6 13.2 0.0041 16.9 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NST1 PF13945.1 EIM88932.1 - 1.8 8.6 7.2 0.069 13.2 0.9 1.5 2 0 0 2 2 2 0 Salt tolerance down-regulator SLD3 PF08639.5 EIM88934.1 - 0.091 11.3 1.3 0.12 10.9 0.9 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 CBS PF00571.23 EIM88935.1 - 5.7e-18 64.4 0.2 6.7e-06 25.7 0.0 4.5 4 0 0 4 4 4 4 CBS domain Cys_Met_Meta_PP PF01053.15 EIM88937.1 - 8.8e-26 90.0 0.0 1.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_A21 PF03566.8 EIM88937.1 - 0.092 10.8 0.1 0.25 9.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase family A21 Cupin_3 PF05899.7 EIM88937.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Thaumatin PF00314.12 EIM88938.1 - 1.4e-15 57.4 9.1 1.6e-15 57.1 6.3 1.1 1 0 0 1 1 1 1 Thaumatin family zf-MYND PF01753.13 EIM88939.1 - 1.3e-07 31.4 11.9 1.3e-07 31.4 8.2 1.8 2 0 0 2 2 2 1 MYND finger GST_N_3 PF13417.1 EIM88940.1 - 3.9e-12 46.2 0.3 8.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM88940.1 - 0.0067 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PGG PF13962.1 EIM88941.1 - 3 7.5 7.6 0.14 11.8 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF791 PF05631.9 EIM88942.1 - 2.8e-68 230.2 7.9 1.5e-55 188.3 0.6 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EIM88942.1 - 1.2e-16 60.4 38.0 1.2e-16 60.4 26.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Rubella_E2 PF05749.6 EIM88942.1 - 0.053 12.7 3.8 0.15 11.2 2.6 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Aldedh PF00171.17 EIM88943.1 - 5.6e-86 288.7 0.0 6.9e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM88943.1 - 0.0016 17.2 0.0 0.0034 16.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) NAD_binding_4 PF07993.7 EIM88944.1 - 1.1e-33 116.2 0.0 2.1e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM88944.1 - 1.8e-17 62.8 0.0 3.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM88944.1 - 3.2e-09 36.5 0.0 5.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM88944.1 - 5e-05 23.4 1.4 0.00011 22.3 0.0 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site KR PF08659.5 EIM88944.1 - 0.0019 17.8 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EIM88944.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM88944.1 - 0.042 12.7 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EIM88944.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIM88944.1 - 0.1 11.2 0.0 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EIM88945.1 - 5.9e-48 163.3 46.6 5.9e-48 163.3 32.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM88945.1 - 1.2e-19 69.9 18.1 1.7e-19 69.4 12.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM88945.1 - 1.3e-11 43.7 12.5 1.3e-11 43.7 8.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1294 PF06961.8 EIM88945.1 - 0.66 9.9 0.0 0.66 9.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) UPF0016 PF01169.14 EIM88947.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.5 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 GMC_oxred_N PF00732.14 EIM88948.1 - 5.5e-65 219.4 0.0 9.6e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM88948.1 - 1.8e-41 141.7 0.0 3.4e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIM88948.1 - 5e-06 25.6 1.2 0.0055 15.6 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM88948.1 - 0.00087 19.2 0.3 0.002 18.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM88948.1 - 0.00092 18.2 0.2 0.0018 17.2 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM88948.1 - 0.028 14.4 0.3 0.59 10.1 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM88948.1 - 0.029 13.2 1.8 0.096 11.5 0.6 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EIM88948.1 - 0.044 13.6 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM88948.1 - 0.085 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 EIM88949.1 - 2.3e-58 197.8 0.0 2.6e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.14 EIM88950.1 - 3.4e-22 78.3 0.0 1.6e-17 62.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM88950.1 - 3.1e-20 73.1 0.0 8.1e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM88950.1 - 1.3e-10 40.7 0.0 4e-07 29.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM88950.1 - 1e-07 32.0 0.0 2.4e-06 27.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM88950.1 - 8.4e-07 29.1 0.1 0.00057 19.9 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIM88950.1 - 0.00064 19.5 0.1 0.082 12.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIM88950.1 - 0.0031 17.8 1.8 0.46 10.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIM88950.1 - 0.0074 15.9 0.2 0.75 9.4 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIM88950.1 - 0.0077 16.2 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EIM88950.1 - 0.0077 15.3 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EIM88950.1 - 0.016 14.2 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family CPSase_L_chain PF00289.17 EIM88950.1 - 0.032 14.3 0.1 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_8 PF13450.1 EIM88950.1 - 0.036 14.0 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIM88950.1 - 0.087 11.6 0.7 1.5 7.5 0.0 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EIM88951.1 - 2.1e-52 178.1 0.0 2.8e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM88951.1 - 6.7e-32 110.7 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM88951.1 - 0.019 15.0 0.7 0.068 13.2 0.5 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM88951.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_88 PF07470.8 EIM88952.1 - 2.9e-22 79.1 0.9 2.9e-22 79.1 0.6 1.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 CNH PF00780.17 EIM88954.1 - 2.2e-17 63.3 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EIM88955.1 - 4.7e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EIM88955.1 - 4.5e-05 23.4 0.0 0.0018 18.2 0.0 3.0 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 RabGAP-TBC PF00566.13 EIM88956.1 - 8.9e-22 77.6 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pex14_N PF04695.8 EIM88956.1 - 1.4 9.0 11.2 7 6.7 3.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Perilipin PF03036.11 EIM88960.1 - 3.1e-12 46.0 9.4 8e-12 44.6 0.1 3.2 1 1 2 3 3 3 2 Perilipin family Apolipoprotein PF01442.13 EIM88960.1 - 0.012 15.0 2.9 0.1 12.1 1.5 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain SATase_N PF06426.9 EIM88960.1 - 0.052 13.8 0.9 0.14 12.4 0.6 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Gp-FAR-1 PF05823.7 EIM88960.1 - 0.13 12.2 1.6 2.7 7.9 0.3 2.7 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.8 EIM88960.1 - 2.1 8.7 7.1 2 8.8 0.4 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NmrA PF05368.8 EIM88961.1 - 1.7e-32 112.5 0.0 2.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM88961.1 - 6.4e-07 29.5 0.0 9.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM88961.1 - 3e-06 26.1 0.1 4.4e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIM88961.1 - 0.0063 15.5 0.2 0.0088 15.0 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIM88961.1 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM88961.1 - 0.032 13.1 0.0 0.061 12.2 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein AsiA PF09010.5 EIM88961.1 - 0.044 13.6 0.5 0.095 12.5 0.3 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A DapB_N PF01113.15 EIM88961.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EIM88962.1 - 4.2e-31 107.9 0.0 5.5e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM88962.1 - 1.5e-07 31.6 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM88962.1 - 7.1e-05 21.6 0.1 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM88962.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amnionless PF14828.1 EIM88963.1 - 0.023 13.2 0.0 0.64 8.4 0.0 2.1 2 0 0 2 2 2 0 Amnionless EphA2_TM PF14575.1 EIM88963.1 - 0.035 14.5 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EIM88963.1 - 0.13 10.5 0.7 0.16 10.1 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E RCR PF12273.3 EIM88963.1 - 0.26 11.8 0.2 0.26 11.8 0.2 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 EIM88963.1 - 0.3 10.4 3.8 1.1 8.6 2.6 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lamp PF01299.12 EIM88963.1 - 7.2 5.6 7.8 0.14 11.2 0.2 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Shisa PF13908.1 EIM88964.1 - 0.0056 16.8 0.0 0.007 16.5 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2324 PF10086.4 EIM88964.1 - 0.029 13.5 0.1 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) Rax2 PF12768.2 EIM88964.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SIT PF15330.1 EIM88964.1 - 0.042 13.9 0.2 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Herpes_gE PF02480.11 EIM88964.1 - 0.066 11.4 0.0 0.089 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EIM88964.1 - 0.085 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1049 PF06305.6 EIM88964.1 - 0.17 11.3 3.2 0.31 10.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SKG6 PF08693.5 EIM88964.1 - 0.68 9.3 8.6 1.6 8.1 5.9 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain AA_permease_2 PF13520.1 EIM88966.1 - 5.8e-69 232.6 53.8 7.3e-69 232.3 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM88966.1 - 2.9e-20 72.0 48.6 4.1e-20 71.5 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.10 EIM88967.1 - 2.2e-75 253.1 0.0 3.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIM88967.1 - 1.6e-35 120.6 0.3 3.6e-35 119.5 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIM88967.1 - 1.1e-29 102.8 0.0 2.3e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIM88967.1 - 9.3e-17 60.3 6.6 1.7e-16 59.5 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIM88967.1 - 9.7e-13 47.6 0.0 3e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat 5_3_exonuc PF01367.15 EIM88968.1 - 0.014 15.6 0.1 0.075 13.2 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NAD_binding_6 PF08030.7 EIM88969.1 - 6.5e-37 126.8 0.0 1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM88969.1 - 1e-23 83.2 0.2 3.3e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EIM88969.1 - 2.4e-13 50.2 16.1 2.4e-13 50.2 11.2 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIM88969.1 - 0.00076 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4131 PF13567.1 EIM88969.1 - 0.43 9.9 4.2 0.14 11.5 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FMO-like PF00743.14 EIM88970.1 - 2.5e-29 101.8 0.0 1.4e-20 73.0 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM88970.1 - 1.3e-14 54.7 0.0 2.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM88970.1 - 0.00011 21.2 0.6 0.0043 16.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIM88970.1 - 0.022 14.5 7.1 0.24 11.1 0.2 4.0 2 2 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIM88970.1 - 0.026 14.5 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIM88970.1 - 0.14 12.4 0.2 26 5.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding p450 PF00067.17 EIM88971.1 - 1.8e-68 231.1 0.0 2.4e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VPS11_C PF12451.3 EIM88971.1 - 0.078 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DUF221 PF02714.10 EIM88972.1 - 6e-105 350.6 18.3 9.5e-105 350.0 12.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIM88972.1 - 6.3e-35 120.0 5.7 6.3e-35 120.0 4.0 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIM88972.1 - 3e-12 46.8 0.1 3e-12 46.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EIM88972.1 - 4.9e-10 39.1 0.9 3.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Phosphate metabolism protein Syntaxin-6_N PF09177.6 EIM88973.1 - 1e-22 80.3 3.4 1.1e-21 76.9 0.2 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EIM88973.1 - 2.8e-14 52.5 2.6 2.8e-14 52.5 1.8 2.2 2 1 0 2 2 2 1 SNARE domain FlaC_arch PF05377.6 EIM88973.1 - 0.0089 15.9 1.6 0.48 10.3 0.1 3.0 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) QRPTase_C PF01729.14 EIM88973.1 - 0.032 13.7 0.1 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3040 PF11239.3 EIM88973.1 - 0.041 13.9 0.1 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3584 PF12128.3 EIM88973.1 - 0.052 10.8 1.4 1.4 6.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EIM88973.1 - 0.065 13.2 5.4 2.1 8.4 0.7 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 EIM88973.1 - 0.092 12.4 1.5 5.7 6.6 0.6 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 EIM88973.1 - 0.13 11.9 1.2 3 7.6 0.0 2.8 2 1 1 3 3 3 0 Prefoldin subunit Laminin_I PF06008.9 EIM88973.1 - 0.13 11.5 4.2 2 7.6 0.3 2.4 2 1 0 2 2 2 0 Laminin Domain I TMF_DNA_bd PF12329.3 EIM88973.1 - 0.3 10.9 4.2 0.91 9.3 0.5 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 EIM88973.1 - 0.35 10.6 4.2 1.1 9.0 0.1 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 EIM88973.1 - 0.55 10.1 0.1 0.55 10.1 0.1 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4200) DUF883 PF05957.8 EIM88973.1 - 0.59 10.5 6.9 1.3 9.4 0.4 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TBCA PF02970.11 EIM88973.1 - 1.5 8.9 7.4 0.69 10.0 0.2 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A Cortex-I_coil PF09304.5 EIM88973.1 - 1.7 8.7 8.4 0.81 9.7 0.7 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil PspA_IM30 PF04012.7 EIM88973.1 - 2 7.7 7.9 4.4 6.6 0.6 2.6 2 1 0 2 2 2 0 PspA/IM30 family Filament PF00038.16 EIM88973.1 - 9.1 5.6 10.9 5.3 6.4 1.1 2.7 2 1 0 2 2 2 0 Intermediate filament protein p450 PF00067.17 EIM88974.1 - 0.0014 17.2 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM88975.1 - 7.1e-49 166.5 0.0 8.6e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PCMT PF01135.14 EIM88976.1 - 6.6e-72 241.4 0.0 7.7e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIM88976.1 - 9e-10 39.1 0.0 1.4e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM88976.1 - 1.8e-07 30.8 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM88976.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIM88976.1 - 1.4e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM88976.1 - 5.6e-05 23.5 0.0 0.00055 20.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM88976.1 - 9.5e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIM88976.1 - 0.0025 16.9 0.0 0.022 13.8 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EIM88976.1 - 0.0089 16.3 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIM88976.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EIM88976.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EIM88976.1 - 0.095 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF4470 PF14737.1 EIM88977.1 - 4.8e-24 84.0 0.0 8.8e-24 83.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM88977.1 - 8.8e-11 41.4 14.3 2.2e-10 40.2 9.9 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EIM88978.1 - 1.9e-05 24.3 0.1 9.1e-05 22.1 0.1 2.2 1 0 0 1 1 1 1 F-box-like MAM33 PF02330.11 EIM88979.1 - 8.6e-36 123.6 0.2 1e-35 123.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein FabA PF07977.8 EIM88979.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain DUF1212 PF06738.7 EIM88982.1 - 5.9e-22 78.0 3.3 5.8e-22 78.0 2.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM88982.1 - 9.3e-10 38.5 30.4 1.6e-08 34.5 5.7 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Sugar_tr PF00083.19 EIM88983.1 - 3.3e-84 283.0 23.5 3.8e-84 282.8 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM88983.1 - 5.8e-20 71.2 36.1 1.7e-19 69.7 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM88983.1 - 2.7e-07 29.3 18.2 2.3e-05 22.9 1.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein PRRSV_2b PF07069.6 EIM88983.1 - 1.2 9.4 5.2 0.35 11.1 0.4 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Lig_chan PF00060.21 EIM88983.1 - 4.8 6.8 11.2 4.2 7.0 0.1 3.4 4 0 0 4 4 4 0 Ligand-gated ion channel GRAB PF10375.4 EIM88984.1 - 6.5e-07 28.7 0.9 1.5e-06 27.6 0.7 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EIM88984.1 - 0.0073 15.5 9.3 0.097 11.8 0.2 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein zf-ZPR1 PF03367.8 EIM88984.1 - 0.49 9.5 4.4 5.9 6.0 0.3 2.5 2 1 0 2 2 2 0 ZPR1 zinc-finger domain Laminin_II PF06009.7 EIM88984.1 - 1.9 8.2 19.7 1 9.0 3.9 2.8 2 1 0 2 2 2 0 Laminin Domain II F-box PF00646.28 EIM88985.1 - 6.6e-07 28.8 0.8 2.7e-06 26.8 0.4 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM88985.1 - 0.0016 18.1 1.2 0.0048 16.5 0.8 1.9 1 0 0 1 1 1 1 F-box-like Histone PF00125.19 EIM88986.1 - 1.3e-21 76.4 0.3 2e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM88986.1 - 2.3e-06 27.5 0.1 5.7e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIM88986.1 - 0.00071 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EIM88986.1 - 0.042 14.3 0.4 0.059 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 EIM88986.1 - 0.047 13.0 0.1 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein RP-C PF03428.8 EIM88986.1 - 0.056 12.8 0.2 0.095 12.1 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 EIM88987.1 - 2.9e-26 91.3 0.0 3.7e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM88987.1 - 3.9e-06 26.8 0.0 5.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-MYND PF01753.13 EIM88988.1 - 7.4e-07 28.9 15.4 1.6e-06 27.8 10.7 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIM88989.1 - 4.8e-08 32.7 15.4 1.3e-07 31.3 10.7 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM88989.1 - 0.5 10.2 5.9 1.4 8.7 4.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.27 EIM88990.1 - 3.6e-19 67.8 8.0 2.5e-06 27.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2512 PF10710.4 EIM88990.1 - 0.097 12.1 1.4 0.2 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Arylsulfotrans PF05935.6 EIM88990.1 - 0.13 10.7 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) BAR_3_WASP_bdg PF10456.4 EIM88990.1 - 0.2 10.8 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein HECT_2 PF09814.4 EIM88992.1 - 8.4e-36 123.4 0.0 1.7e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF812 PF05667.6 EIM88992.1 - 0.0038 15.7 1.0 0.0066 15.0 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PLA2_B PF01735.13 EIM88993.1 - 4.7e-67 226.2 14.5 1.9e-63 214.3 10.0 3.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EIM88994.1 - 1.6e-66 224.5 15.3 1.3e-63 214.9 10.6 3.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Homoserine_dh PF00742.14 EIM88995.1 - 5.4e-47 159.7 0.0 7.2e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EIM88995.1 - 1.4e-16 60.9 0.0 2.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EIM88995.1 - 0.0098 16.1 0.0 0.034 14.4 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ArsB PF02040.10 EIM88996.1 - 4.5e-15 55.5 15.4 1.9e-07 30.4 4.2 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein PPTA PF01239.17 EIM88998.1 - 7.8e-45 148.4 12.1 2.9e-09 35.8 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.17 EIM88999.1 - 1.1e-13 50.6 0.0 1.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM88999.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RHS_repeat PF05593.9 EIM88999.1 - 0.28 11.4 2.5 0.35 11.1 0.1 2.3 2 1 0 2 2 2 0 RHS Repeat RNA_pol_3_Rpc31 PF11705.3 EIM89000.1 - 1.7e-34 119.7 22.9 3.2e-34 118.9 15.8 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 COPI_C PF06957.6 EIM89000.1 - 6.9 5.0 10.7 43 2.4 7.7 1.8 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Peptidase_A4 PF01828.12 EIM89002.1 - 1.3e-77 259.5 14.2 1.6e-77 259.2 9.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S9 PF00326.16 EIM89003.1 - 2.4e-37 128.2 0.0 4.6e-37 127.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM89003.1 - 9.3e-11 41.6 0.0 2.5e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EIM89003.1 - 9.4e-06 25.1 0.3 0.81 9.4 0.1 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat LIP PF03583.9 EIM89003.1 - 0.0028 16.9 0.3 0.005 16.0 0.2 1.3 1 0 0 1 1 1 1 Secretory lipase DLH PF01738.13 EIM89003.1 - 0.0032 16.7 0.1 0.0071 15.6 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.23 EIM89003.1 - 0.012 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family BAAT_C PF08840.6 EIM89003.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Oxidored_FMN PF00724.15 EIM89005.1 - 2.5e-71 240.4 0.0 3.2e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EIM89005.1 - 0.0015 17.4 0.0 0.0031 16.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DDE_1 PF03184.14 EIM89006.1 - 1.1e-10 41.0 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIM89007.1 - 4.7e-10 38.9 0.0 4.7e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PLAT PF01477.18 EIM89007.1 - 0.027 14.8 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 PLAT/LH2 domain CPSF100_C PF13299.1 EIM89008.1 - 6.9 6.8 11.3 0.41 10.8 1.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal 2-oxoacid_dh PF00198.18 EIM89011.1 - 3.5e-57 193.3 0.0 5.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIM89011.1 - 4.2e-18 64.7 1.0 7.1e-18 64.0 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EIM89011.1 - 0.0014 18.3 0.1 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF605 PF04652.11 EIM89011.1 - 0.028 13.8 13.6 0.035 13.5 9.4 1.1 1 0 0 1 1 1 0 Vta1 like GMP_PDE_delta PF05351.6 EIM89011.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 GMP-PDE, delta subunit Nucleo_P87 PF07267.6 EIM89011.1 - 0.31 9.6 5.4 0.04 12.6 0.7 1.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 SAP18 PF06487.7 EIM89012.1 - 1.2e-22 79.9 0.0 1.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Peptidase_M18 PF02127.10 EIM89013.1 - 3.4e-127 424.5 0.0 3.9e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_transf_20 PF00982.16 EIM89014.1 - 1.1e-144 482.4 0.0 1.8e-144 481.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIM89014.1 - 1.5e-72 243.3 0.0 3.5e-72 242.1 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase DUF4470 PF14737.1 EIM89016.1 - 8e-24 83.2 0.0 1.7e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIM89016.1 - 7e-09 35.4 13.1 1.7e-08 34.1 9.1 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EIM89017.1 - 6.1e-11 41.8 0.2 1.9e-10 40.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.17 EIM89018.1 - 2e-47 158.7 0.0 1.2e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89018.1 - 2.9e-35 120.0 0.0 2.3e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89018.1 - 3.4e-17 62.0 0.0 0.00024 20.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EIM89018.1 - 1.9e-06 27.7 43.9 3.6e-06 26.8 30.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Limkain-b1 PF11608.3 EIM89018.1 - 0.00088 18.9 0.0 0.0076 15.9 0.0 2.5 4 1 0 4 4 4 1 Limkain b1 DUF3343 PF11823.3 EIM89018.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) MIP-T3 PF10243.4 EIM89018.1 - 9.3 4.5 22.3 13 4.1 15.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1212 PF06738.7 EIM89019.1 - 7e-23 81.0 0.7 7e-23 81.0 0.5 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIM89019.1 - 1.5e-11 44.3 24.8 1.9e-11 44.0 3.7 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) L31 PF09784.4 EIM89019.1 - 0.031 14.3 0.2 0.12 12.4 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 PH_9 PF15410.1 EIM89022.1 - 0.00051 20.1 0.0 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIM89022.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 PH domain zf-MYND PF01753.13 EIM89028.1 - 9.6e-05 22.1 10.8 9.6e-05 22.1 7.5 1.8 2 0 0 2 2 2 1 MYND finger DUF1769 PF08588.5 EIM89035.1 - 1.4e-15 56.9 0.0 2.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Sdh5 PF03937.11 EIM89038.1 - 2.2e-25 88.1 0.4 2.6e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase EmrE PF13536.1 EIM89040.1 - 1.6 8.9 12.0 2.8 8.1 5.0 2.9 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Gly_transf_sug PF04488.10 EIM89041.1 - 0.00014 22.2 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Mito_fiss_reg PF05308.6 EIM89041.1 - 0.15 11.3 6.7 0.23 10.7 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DEAD PF00270.24 EIM89042.1 - 8.7e-41 139.2 0.1 1.7e-40 138.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM89042.1 - 1.1e-23 82.8 0.1 2.3e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EIM89042.1 - 0.012 14.7 0.2 0.032 13.3 0.1 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-C4H2 PF10146.4 EIM89042.1 - 2 8.3 6.8 4 7.3 4.7 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein zf-MYND PF01753.13 EIM89043.1 - 0.43 10.4 16.1 0.051 13.4 8.0 1.8 2 0 0 2 2 2 0 MYND finger zf-MYND PF01753.13 EIM89044.1 - 1.3e-06 28.1 9.4 1.3e-06 28.1 6.5 2.1 2 1 0 2 2 2 1 MYND finger HAD_2 PF13419.1 EIM89045.1 - 2.9e-24 86.2 0.0 3.8e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM89045.1 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zinc-ribbons_6 PF07191.7 EIM89046.1 - 0.048 13.4 1.6 0.079 12.7 1.1 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF2076 PF09849.4 EIM89046.1 - 0.11 12.4 3.9 0.14 12.1 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EIM89046.1 - 0.17 11.8 3.7 0.37 10.7 2.6 1.5 1 1 0 1 1 1 0 CHCH domain Tim44 PF04280.10 EIM89047.1 - 2.7e-06 27.4 0.3 0.016 15.1 0.1 3.0 3 0 0 3 3 3 2 Tim44-like domain Nitroreductase PF00881.19 EIM89048.1 - 1.7e-07 31.2 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Cauli_VI PF01693.11 EIM89048.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin MFS_1 PF07690.11 EIM89050.1 - 2.1e-38 131.9 48.4 2.1e-38 131.9 33.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM89050.1 - 4.2e-18 64.8 26.6 8.7e-18 63.8 18.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM89050.1 - 5e-13 48.4 15.6 5e-13 48.4 10.8 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter GDPD PF03009.12 EIM89051.1 - 3.1e-28 98.9 0.0 4.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIM89051.1 - 0.11 12.7 1.5 0.4 10.9 1.1 2.1 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family HhH-GPD PF00730.20 EIM89053.1 - 5.9e-20 71.5 0.0 1.9e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIM89053.1 - 4e-09 35.6 0.0 3.7e-08 32.6 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EIM89053.1 - 0.03 14.4 0.1 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 EIM89053.1 - 0.73 10.1 4.3 1.7 8.9 3.0 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Nitroreductase PF00881.19 EIM89054.1 - 2.5e-12 46.9 0.0 3e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family PHD PF00628.24 EIM89055.1 - 0.022 14.4 7.1 0.15 11.7 2.8 2.5 2 0 0 2 2 2 0 PHD-finger Tsg PF04668.7 EIM89055.1 - 0.79 9.9 5.8 0.61 10.2 2.9 1.5 1 1 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region XPG_I_2 PF12813.2 EIM89056.1 - 0.017 14.6 0.4 0.046 13.1 0.0 1.8 2 1 1 3 3 3 0 XPG domain containing dsrm PF00035.20 EIM89057.1 - 0.016 15.7 0.1 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif Phe_hydrox_dim PF07976.7 EIM89058.1 - 0.011 15.3 0.1 0.031 13.8 0.1 1.7 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain TIP39 PF14980.1 EIM89058.1 - 0.12 11.9 0.3 14 5.3 0.0 2.5 2 0 0 2 2 2 0 TIP39 peptide Sec62 PF03839.11 EIM89059.1 - 9.6e-48 162.5 4.3 3.5e-47 160.6 1.9 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 TPR_12 PF13424.1 EIM89060.1 - 4.2e-08 32.9 9.6 0.00028 20.7 0.2 4.6 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89060.1 - 1.6e-07 30.7 1.1 0.0092 15.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89060.1 - 6.6e-06 25.6 3.8 0.24 11.0 0.1 4.1 2 2 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EIM89060.1 - 1.2e-05 24.6 0.1 0.037 13.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89060.1 - 0.0033 17.1 2.9 0.83 9.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89060.1 - 0.008 16.8 5.8 2.1 9.1 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM89060.1 - 0.12 12.9 0.2 1.7 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89060.1 - 0.52 11.0 10.5 22 6.0 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF1488 PF07369.6 EIM89061.1 - 0.059 13.2 0.1 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Myb_DNA-binding PF00249.26 EIM89062.1 - 0.00017 21.5 0.1 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1-DNA-bind PF09197.5 EIM89062.1 - 0.0083 16.6 0.3 4.7 7.7 0.0 3.0 3 0 0 3 3 3 2 Rap1, DNA-binding CAF1A PF12253.3 EIM89062.1 - 0.13 12.4 1.0 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A RRM_3 PF08777.6 EIM89063.1 - 0.57 10.0 0.0 0.57 10.0 0.0 2.3 3 0 0 3 3 3 0 RNA binding motif HAD_2 PF13419.1 EIM89064.1 - 6.8e-25 88.3 0.0 2.7e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIM89064.1 - 0.043 14.2 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM89064.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like WD40 PF00400.27 EIM89066.1 - 1.6e-110 357.4 30.3 2.1e-13 49.5 0.1 10.6 10 0 0 10 10 10 10 WD domain, G-beta repeat NACHT PF05729.7 EIM89066.1 - 5.6e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EIM89066.1 - 9.9e-08 31.4 7.7 3.7 7.3 0.0 9.2 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIM89066.1 - 1e-07 30.5 5.0 0.15 10.1 0.0 6.2 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIM89066.1 - 1.9e-07 30.2 0.2 0.046 12.4 0.3 4.5 1 1 2 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 EIM89066.1 - 9.5e-06 25.1 4.5 0.4 10.0 0.2 4.7 2 2 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 EIM89066.1 - 4.5e-05 22.6 3.6 3.8 6.9 0.0 6.0 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 EIM89066.1 - 5.2e-05 21.6 0.0 2.6 6.1 0.0 4.4 3 1 2 5 5 5 2 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EIM89066.1 - 8.7e-05 20.9 0.0 0.0018 16.6 0.0 2.5 3 0 0 3 3 3 1 Cytochrome D1 heme domain AAA_16 PF13191.1 EIM89066.1 - 0.00032 20.7 0.1 0.0014 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIM89066.1 - 0.048 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF1652 PF07865.6 EIM89066.1 - 0.088 12.4 0.0 19 4.9 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1652) DUF1999 PF09390.5 EIM89066.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) EXS PF03124.9 EIM89067.1 - 4.5e-70 236.3 11.7 6.2e-70 235.9 8.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EIM89067.1 - 1.1e-32 113.9 0.0 3.6e-32 112.2 0.0 1.9 1 1 0 1 1 1 1 SPX domain MIP-T3 PF10243.4 EIM89067.1 - 1.5 7.1 16.2 2.6 6.4 11.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PHD PF00628.24 EIM89068.1 - 0.0083 15.8 5.5 0.012 15.2 0.5 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EIM89068.1 - 0.016 14.5 1.7 0.032 13.5 0.0 2.2 2 0 0 2 2 2 0 PHD-finger DOR PF14839.1 EIM89068.1 - 0.12 12.0 0.1 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 DOR family C1_3 PF07649.7 EIM89068.1 - 1.4 9.0 6.9 7.9 6.6 1.5 2.7 2 0 0 2 2 2 0 C1-like domain Peptidase_S9 PF00326.16 EIM89069.1 - 1.9e-28 99.1 0.0 2.9e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIM89069.1 - 2e-12 47.5 0.2 5.2e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM89069.1 - 2.4e-10 40.3 0.1 6.2e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89069.1 - 4.5e-05 23.1 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIM89069.1 - 0.0024 17.3 0.0 0.042 13.3 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EIM89069.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EIM89069.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.7 EIM89069.1 - 0.047 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 EIM89069.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 EIM89069.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Vps16_C PF04840.7 EIM89070.1 - 3.4e-82 275.9 0.1 4.6e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EIM89070.1 - 2.4e-81 273.3 0.0 3.3e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Arrestin_N PF00339.24 EIM89071.1 - 0.00065 19.5 0.0 0.0022 17.8 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.19 EIM89072.1 - 1.2e-93 314.1 18.3 1.5e-93 313.8 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM89072.1 - 1.7e-38 132.2 37.0 8.8e-37 126.6 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM89072.1 - 0.0018 18.0 1.1 0.5 10.2 0.1 3.0 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 EIM89072.1 - 0.024 12.7 8.6 0.31 9.0 0.7 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF155 PF02582.9 EIM89073.1 - 2.9e-44 151.0 0.0 4.7e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2305 PF10230.4 EIM89073.1 - 0.02 14.3 0.4 0.038 13.4 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ATP-synt_10 PF05176.9 EIM89075.1 - 2.1e-68 230.3 0.0 2.5e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Histone PF00125.19 EIM89076.1 - 2.9e-26 91.3 0.0 3.7e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM89076.1 - 3.9e-06 26.8 0.0 5.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF563 PF04577.9 EIM89077.1 - 4.3e-07 30.0 0.0 1.3e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) F-box PF00646.28 EIM89081.1 - 0.03 13.9 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.28 EIM89083.1 - 0.047 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain TPT PF03151.11 EIM89086.1 - 2.2e-21 76.1 11.4 2.2e-21 76.1 7.9 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIM89086.1 - 0.004 16.1 17.8 0.031 13.1 12.3 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EIM89086.1 - 0.16 12.1 22.3 0.037 14.2 2.1 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter LSM PF01423.17 EIM89087.1 - 6.1e-14 51.3 0.1 7.3e-14 51.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain zf-MYND PF01753.13 EIM89088.1 - 2.6e-07 30.3 16.4 5e-07 29.4 11.4 1.5 1 0 0 1 1 1 1 MYND finger AAA_12 PF13087.1 EIM89090.1 - 1.3e-38 132.3 0.0 2.9e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIM89090.1 - 9.3e-34 116.4 4.7 2.5e-09 37.4 0.0 6.2 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EIM89090.1 - 2.1e-25 89.7 26.0 2.1e-25 89.6 0.0 7.3 7 2 0 7 7 7 1 AAA domain AAA_19 PF13245.1 EIM89090.1 - 4.3e-14 52.0 8.4 1e-06 28.3 0.0 5.6 7 0 0 7 7 5 3 Part of AAA domain AAA_22 PF13401.1 EIM89090.1 - 1.1e-10 41.7 6.9 0.32 11.1 0.0 8.2 6 3 0 6 6 6 3 AAA domain Viral_helicase1 PF01443.13 EIM89090.1 - 1.6e-09 37.6 0.2 0.1 12.0 0.0 5.9 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EIM89090.1 - 4.4e-09 36.1 0.4 0.074 12.7 0.0 4.6 4 0 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIM89090.1 - 1.6e-07 32.1 15.9 0.044 14.6 0.0 6.6 6 0 0 6 6 4 3 AAA domain Mg_chelatase PF01078.16 EIM89090.1 - 1.6e-07 30.7 0.1 0.45 9.6 0.0 4.3 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EIM89090.1 - 3.4e-06 27.3 5.4 0.45 10.8 0.0 5.3 4 0 0 4 4 4 2 AAA domain DUF2075 PF09848.4 EIM89090.1 - 3.7e-06 26.1 3.4 0.0015 17.5 0.0 5.3 6 0 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EIM89090.1 - 6.3e-06 26.1 0.7 1.3 8.9 0.0 4.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EIM89090.1 - 6.8e-06 26.2 0.1 2 8.6 0.0 4.7 4 0 0 4 4 4 2 RNA helicase IstB_IS21 PF01695.12 EIM89090.1 - 7.6e-06 25.4 0.3 2.3 7.6 0.0 3.9 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIM89090.1 - 9.5e-06 25.1 0.8 3.2 7.1 0.0 5.0 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.1 EIM89090.1 - 0.00015 21.8 13.1 0.27 11.1 0.0 5.2 4 0 0 4 4 3 3 AAA ATPase domain PhoH PF02562.11 EIM89090.1 - 0.0014 17.8 0.7 1.4 8.1 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein Torsin PF06309.6 EIM89090.1 - 0.013 15.3 0.3 19 5.1 0.0 3.6 3 0 0 3 3 3 0 Torsin KaiC PF06745.8 EIM89090.1 - 0.036 13.1 3.3 8.5 5.4 0.1 3.6 3 1 0 3 3 3 0 KaiC AAA_24 PF13479.1 EIM89090.1 - 0.044 13.3 9.2 3.2 7.2 0.0 4.9 6 0 0 6 6 6 0 AAA domain AAA_25 PF13481.1 EIM89090.1 - 0.06 12.7 13.2 0.077 12.3 0.0 4.4 4 0 0 4 4 3 0 AAA domain Transp_cyt_pur PF02133.10 EIM89091.1 - 1.9e-105 352.9 37.9 1.1e-67 228.4 19.0 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2422 PF10337.4 EIM89092.1 - 0.08 11.7 1.9 0.11 11.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Cytadhesin_P30 PF07271.6 EIM89092.1 - 0.11 11.7 0.5 0.18 11.0 0.3 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 ATP-synt_E PF05680.7 EIM89092.1 - 3.7 7.5 11.6 1.5 8.8 2.9 2.5 2 0 0 2 2 2 0 ATP synthase E chain Pkinase PF00069.20 EIM89093.1 - 1.7e-50 171.6 0.0 2.3e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89093.1 - 5.1e-27 94.5 0.0 6.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIM89093.1 - 0.00029 19.7 0.0 0.00029 19.7 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EIM89093.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIM89093.1 - 0.017 14.8 0.1 0.068 12.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_7 PF13499.1 EIM89093.1 - 0.073 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PDT PF00800.13 EIM89094.1 - 1.8e-49 167.7 0.0 2.3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ELYS PF13934.1 EIM89095.1 - 4.4e-39 134.5 0.0 5.1e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly PITH PF06201.8 EIM89096.1 - 5.1e-33 113.9 0.0 6.1e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.10 EIM89097.1 - 5.9e-17 60.7 0.1 3.9e-16 58.1 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIM89097.1 - 2.6e-11 43.1 0.2 6.7e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain NUP PF06516.6 EIM89098.1 - 3.5e-119 397.3 0.0 3.9e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) p450 PF00067.17 EIM89101.1 - 2.2e-75 253.9 0.0 4.1e-75 253.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.28 EIM89102.1 - 0.0025 17.4 0.2 0.0059 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM89102.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 EIM89103.1 - 4.8e-19 68.2 30.8 4.8e-19 68.2 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIM89103.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Sec23_trunk PF04811.10 EIM89104.1 - 1e-72 244.4 0.0 1.7e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIM89104.1 - 1.3e-24 85.6 0.2 3e-24 84.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIM89104.1 - 7.5e-17 60.6 7.1 1.7e-16 59.4 4.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIM89104.1 - 4e-16 59.2 0.0 9.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIM89104.1 - 9.9e-10 37.9 0.0 2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 EIM89104.1 - 3.3e-05 23.6 0.2 3.3e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 WW domain VWA_2 PF13519.1 EIM89104.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3458 PF11940.3 EIM89104.1 - 0.038 12.8 0.4 0.06 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Peptidase_M20 PF01546.23 EIM89105.1 - 2.4e-21 76.0 0.2 3.3e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM89105.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIM89105.1 - 0.037 13.7 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M28 Thaumatin PF00314.12 EIM89106.1 - 2e-43 148.3 12.0 2.7e-43 147.9 8.3 1.2 1 0 0 1 1 1 1 Thaumatin family SKG6 PF08693.5 EIM89106.1 - 0.0061 15.8 0.1 0.016 14.4 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain adh_short PF00106.20 EIM89107.1 - 6.2e-34 117.3 0.7 7.9e-34 116.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89107.1 - 4.7e-26 92.0 0.0 5.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89107.1 - 1.6e-19 70.2 0.4 2.2e-19 69.8 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM89107.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM89107.1 - 0.014 15.4 0.5 0.047 13.7 0.2 1.8 2 1 0 2 2 2 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EIM89107.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.6 EIM89107.1 - 0.022 14.2 0.0 0.1 12.0 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain Eno-Rase_NADH_b PF12242.3 EIM89107.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_trans_4_4 PF13579.1 EIM89107.1 - 0.12 12.5 0.1 0.58 10.2 0.1 2.0 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain ADH_N PF08240.7 EIM89108.1 - 1.9e-28 98.3 1.5 2.9e-28 97.7 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM89108.1 - 6.9e-24 83.8 0.0 2.1e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM89108.1 - 0.00019 22.3 0.0 0.00048 21.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIM89108.1 - 0.0024 17.4 0.8 0.011 15.2 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 EIM89108.1 - 0.0025 18.3 0.5 0.01 16.4 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EIM89108.1 - 0.0058 16.0 0.1 0.024 14.0 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EIM89108.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 EIM89108.1 - 0.012 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EIM89108.1 - 0.018 15.1 0.2 0.94 9.5 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIM89108.1 - 0.026 13.4 0.1 0.037 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FtsJ PF01728.14 EIM89108.1 - 0.048 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pyr_redox_3 PF13738.1 EIM89108.1 - 0.052 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Met_10 PF02475.11 EIM89108.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CPSase_L_chain PF00289.17 EIM89108.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Methyltransf_26 PF13659.1 EIM89108.1 - 0.15 12.1 0.6 0.31 11.0 0.4 1.7 1 1 0 1 1 1 0 Methyltransferase domain Hydantoinase_A PF01968.13 EIM89108.1 - 0.15 11.0 1.3 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase YdfZ PF14001.1 EIM89108.1 - 0.47 10.7 2.2 0.64 10.3 0.0 2.2 3 0 0 3 3 2 0 YdfZ protein Peptidase_S41 PF03572.13 EIM89109.1 - 2.6e-05 23.6 0.0 8.4e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 adh_short PF00106.20 EIM89110.1 - 9.7e-21 74.4 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89110.1 - 3e-16 59.9 0.0 3.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM89110.1 - 4.6e-05 22.9 0.1 0.0002 20.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM89110.1 - 0.0017 18.3 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EIM89110.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EIM89110.1 - 0.036 13.7 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EIM89110.1 - 0.073 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.8 EIM89110.1 - 0.14 10.7 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Pectinacetylesterase Ole-e-6 PF09253.5 EIM89110.1 - 0.4 10.3 1.5 0.72 9.5 1.0 1.3 1 0 0 1 1 1 0 Pollen allergen ole e 6 OPT PF03169.10 EIM89111.1 - 2.2e-90 303.9 42.3 2.5e-90 303.7 29.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 EIM89112.1 - 6.4e-13 48.9 0.1 3.5e-12 46.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89112.1 - 1.2e-08 35.0 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89112.1 - 0.00023 20.8 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EIM89112.1 - 0.029 14.7 0.1 2.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.14 EIM89112.1 - 0.075 12.9 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain ubiquitin PF00240.18 EIM89113.1 - 7.6e-14 50.8 0.0 1.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM89113.1 - 6.2e-06 25.8 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 EIM89113.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Ndufs5 PF10200.4 EIM89114.1 - 6.3e-06 26.0 0.8 7.6e-06 25.8 0.5 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 EIM89114.1 - 1.5e-05 24.6 2.0 2.2e-05 24.1 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIM89114.1 - 0.003 17.4 2.7 0.0035 17.2 0.9 1.7 1 1 1 2 2 2 2 CHCH domain DUF3128 PF11326.3 EIM89114.1 - 0.0081 16.2 3.0 0.017 15.2 2.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 EIM89114.1 - 0.034 14.1 1.0 0.051 13.6 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 PADR1 PF08063.7 EIM89114.1 - 0.27 10.6 3.9 7.7 6.0 0.0 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain COX6B PF02297.12 EIM89114.1 - 4.3 7.4 8.1 1.3e+02 2.6 5.6 2.1 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb HemX PF04375.9 EIM89115.1 - 0.036 12.6 6.0 0.055 12.0 4.1 1.2 1 0 0 1 1 1 0 HemX PX PF00787.19 EIM89116.1 - 1.5e-18 66.6 0.0 3.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EIM89116.1 - 4.5e-16 58.8 0.3 3.2e-14 52.7 0.6 2.1 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 EIM89116.1 - 0.00055 19.2 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NUP PF06516.6 EIM89117.1 - 2.4e-119 397.8 0.0 2.8e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF424 PF04242.8 EIM89117.1 - 0.11 12.5 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Aldo_ket_red PF00248.16 EIM89119.1 - 5.4e-48 163.2 0.0 6.4e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.15 EIM89120.1 - 1.2e-36 126.4 0.0 8.3e-32 110.5 0.0 2.9 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family NUP PF06516.6 EIM89121.1 - 8.3e-114 379.6 0.0 9.7e-114 379.4 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) NUP PF06516.6 EIM89122.1 - 2.3e-121 404.4 0.0 2.8e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF3285 PF11688.3 EIM89123.1 - 0.12 12.0 1.7 0.3 10.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Pro-kuma_activ PF09286.6 EIM89124.1 - 4.2e-37 127.3 0.0 8.5e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM89124.1 - 4.5e-08 32.5 0.3 4.5e-08 32.5 0.2 1.7 2 0 0 2 2 2 1 Subtilase family PIG-L PF02585.12 EIM89125.1 - 4.8e-17 62.6 0.0 2.1e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase TFIIE_alpha PF02002.12 EIM89126.1 - 1.7e-17 62.8 0.2 2.8e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EIM89126.1 - 1.2e-05 24.5 0.5 2.7e-05 23.4 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIE-A_C-term PF11521.3 EIM89126.1 - 0.00022 21.1 0.1 0.0008 19.3 0.1 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Bul1_N PF04425.7 EIM89126.1 - 0.019 13.5 0.0 0.043 12.3 0.0 1.5 1 0 0 1 1 1 0 Bul1 N terminus ADK_lid PF05191.9 EIM89126.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2 PF00096.21 EIM89126.1 - 0.098 13.0 2.6 0.28 11.5 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rrf2 PF02082.15 EIM89126.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator zf-H2C2_2 PF13465.1 EIM89126.1 - 0.2 12.0 0.5 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double domain DUF1610 PF07754.6 EIM89126.1 - 4.2 7.5 5.1 1.7 8.8 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Acetyltransf_7 PF13508.1 EIM89127.1 - 0.00036 20.6 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM89127.1 - 0.0087 16.1 0.0 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIM89127.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 EIM89127.1 - 0.024 14.6 0.1 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EIM89127.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CMD PF02627.15 EIM89130.1 - 2.2e-07 30.5 0.1 4.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family LRR_6 PF13516.1 EIM89131.1 - 5.5e-05 22.8 7.7 3.5 7.9 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat Di19_C PF14571.1 EIM89131.1 - 3.3 8.0 7.2 0.98 9.7 0.9 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF1770 PF08589.5 EIM89133.1 - 0.00055 20.4 0.2 0.0012 19.4 0.1 1.7 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) adh_short PF00106.20 EIM89134.1 - 2.2e-12 47.2 0.6 3.3e-11 43.3 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89134.1 - 1.9e-11 44.2 0.0 3.6e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89134.1 - 1.8e-06 27.7 0.1 3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIM89134.1 - 0.00093 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CMD PF02627.15 EIM89135.1 - 1.8e-09 37.3 0.0 6.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF3455 PF11937.3 EIM89136.1 - 1.9e-25 89.8 0.1 2.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3455 PF11937.3 EIM89137.1 - 7e-29 101.0 0.0 9.5e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pup PF05639.6 EIM89138.1 - 0.022 15.2 0.2 0.56 10.7 0.1 2.3 2 0 0 2 2 2 0 Pup-like protein DUF2009 PF09418.5 EIM89138.1 - 0.068 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Rep_fac-A_3 PF08661.6 EIM89139.1 - 3.4e-21 75.1 0.0 4e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1602 PF07673.9 EIM89140.1 - 0.0024 17.3 0.0 0.0073 15.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1602) UQ_con PF00179.21 EIM89141.1 - 6.5e-52 174.6 0.0 7.4e-52 174.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM89141.1 - 0.0001 22.0 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIM89141.1 - 0.0014 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIM89141.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Nup96 PF12110.3 EIM89144.1 - 1.1e-72 244.6 0.0 1.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 MFS_1 PF07690.11 EIM89145.1 - 8.6e-22 77.3 27.2 8.6e-22 77.3 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HpcH_HpaI PF03328.9 EIM89146.1 - 1.3e-32 112.4 0.2 2.1e-32 111.7 0.1 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EIM89146.1 - 0.00059 18.5 0.1 0.0017 17.0 0.1 1.6 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain Bac_luciferase PF00296.15 EIM89146.1 - 0.031 13.4 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase MFS_1 PF07690.11 EIM89147.1 - 1.5e-38 132.4 71.3 3.3e-34 118.1 35.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EIM89148.1 - 8.5e-24 83.4 24.2 5.5e-11 42.3 3.6 4.4 4 1 0 4 4 4 4 LIM domain Coatomer_WDAD PF04053.9 EIM89149.1 - 2.5e-140 468.2 0.0 5.8e-140 466.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EIM89149.1 - 6.2e-93 311.6 0.0 9.4e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EIM89149.1 - 1.9e-58 192.3 10.2 5.3e-11 41.9 0.3 8.3 10 0 0 10 10 10 6 WD domain, G-beta repeat Nup160 PF11715.3 EIM89149.1 - 0.0046 15.1 3.7 0.14 10.2 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 TPR_16 PF13432.1 EIM89149.1 - 0.042 14.5 5.3 1.2 9.9 2.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4511 PF14974.1 EIM89149.1 - 0.16 11.7 0.0 0.48 10.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) Clathrin PF00637.15 EIM89149.1 - 0.25 10.9 0.1 0.85 9.2 0.1 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_14 PF13428.1 EIM89149.1 - 1.5 9.6 7.8 94 4.0 1.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat XPG_I PF00867.13 EIM89150.1 - 2.1e-16 59.7 0.0 6.3e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EIM89150.1 - 5e-06 26.7 0.0 9.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EIM89150.1 - 0.0057 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CLTH PF10607.4 EIM89151.1 - 2.5e-33 114.7 0.1 4.3e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EIM89151.1 - 2.6e-06 27.0 0.0 2.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Bacillus_HBL PF05791.6 EIM89151.1 - 0.027 13.8 0.3 0.096 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) U-box PF04564.10 EIM89151.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 U-box domain Phasin_2 PF09361.5 EIM89151.1 - 0.32 11.0 1.6 22 5.1 0.2 2.4 2 0 0 2 2 2 0 Phasin protein PIG-S PF10510.4 EIM89154.1 - 3.8e-118 395.3 11.3 3e-107 359.4 2.2 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Ras PF00071.17 EIM89157.1 - 6.1e-10 38.7 0.0 8.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89157.1 - 7.8e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein NAC PF01849.13 EIM89158.1 - 1.9e-20 72.1 0.1 3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 NAC domain Acetyltransf_1 PF00583.19 EIM89159.1 - 1.2e-14 54.0 0.0 2.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM89159.1 - 3.4e-06 27.1 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM89159.1 - 3.6e-06 27.0 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIM89159.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM89159.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM89159.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EIM89159.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EIM89159.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cofilin_ADF PF00241.15 EIM89160.1 - 3.9e-19 68.7 0.1 4.4e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neugrin PF06413.6 EIM89161.1 - 1.3e-12 48.0 0.1 1.5e-12 47.8 0.1 1.0 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EIM89161.1 - 8.6e-06 25.8 0.0 8.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 p450 PF00067.17 EIM89162.1 - 5.3e-28 97.7 0.0 1.7e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 HlyIII PF03006.15 EIM89163.1 - 3.5e-53 180.2 19.3 4.3e-53 180.0 13.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Glyco_transf_4 PF13439.1 EIM89163.1 - 0.03 14.0 0.7 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Rotamase PF00639.16 EIM89164.1 - 1.8e-19 70.2 0.7 2.4e-19 69.8 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIM89164.1 - 7.9e-19 68.0 0.2 1.4e-18 67.2 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EIM89164.1 - 3.8e-06 27.5 1.4 1.5e-05 25.6 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain AA_permease PF00324.16 EIM89167.1 - 1.9e-114 382.6 41.6 2.3e-114 382.3 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM89167.1 - 2e-31 109.0 44.7 2.7e-31 108.5 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.19 EIM89168.1 - 7e-43 146.8 0.1 8.2e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM89168.1 - 2.3e-05 24.5 0.0 0.039 13.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM89168.1 - 0.0014 18.6 0.0 0.0051 16.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM89168.1 - 0.021 15.2 0.1 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM89168.1 - 0.036 13.1 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIM89168.1 - 0.083 11.9 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EIM89168.1 - 0.092 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Tyrosinase PF00264.15 EIM89169.1 - 2.2e-24 86.8 2.9 3.3e-24 86.3 2.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase 3Beta_HSD PF01073.14 EIM89171.1 - 2.9e-06 26.1 0.0 5.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM89171.1 - 1.6e-05 24.4 0.0 0.00024 20.5 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM89171.1 - 5.2e-05 23.3 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM89171.1 - 7.7e-05 22.0 0.2 0.00011 21.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIM89171.1 - 0.0068 15.3 0.0 0.029 13.2 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein Serglycin PF04360.7 EIM89172.1 - 0.0083 15.8 0.6 0.0097 15.6 0.4 1.2 1 0 0 1 1 1 1 Serglycin DUF3042 PF11240.3 EIM89172.1 - 0.031 14.0 0.2 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF3597 PF12200.3 EIM89172.1 - 0.073 13.4 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Sporozoite_P67 PF05642.6 EIM89172.1 - 0.14 10.0 5.5 0.15 9.9 3.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen KAR9 PF08580.5 EIM89172.1 - 0.38 8.9 3.5 0.46 8.6 2.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MMR_HSR1 PF01926.18 EIM89174.1 - 1.2e-21 76.7 0.2 4e-16 59.0 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM89174.1 - 5.8e-08 32.1 0.1 4.8e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIM89174.1 - 4.5e-05 22.9 0.0 0.0018 17.7 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIM89174.1 - 0.00014 22.3 0.0 0.31 11.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EIM89174.1 - 0.0002 21.2 0.1 0.21 11.3 0.0 2.9 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EIM89174.1 - 0.00067 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 EIM89174.1 - 0.0016 17.3 0.1 0.0032 16.2 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EIM89174.1 - 0.0095 15.9 0.2 0.67 9.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EIM89174.1 - 0.058 12.8 0.0 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EIM89174.1 - 0.1 13.3 0.1 4.3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Virul_Fac PF10139.4 EIM89174.1 - 0.26 9.1 0.0 0.38 8.6 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor PARP PF00644.15 EIM89175.1 - 3.9e-10 39.5 1.9 1.8e-08 34.1 0.6 2.8 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Perm-CXXC PF15629.1 EIM89175.1 - 0.0046 16.9 1.5 0.0046 16.9 1.1 3.7 3 0 0 3 3 3 1 Permuted single zf-CXXC unit Ras PF00071.17 EIM89176.1 - 1.5e-26 92.7 0.0 2.3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89176.1 - 1.1e-06 29.0 0.0 2.7e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein KaiC PF06745.8 EIM89176.1 - 0.022 13.8 0.0 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 EIM89176.1 - 0.046 13.7 0.0 0.24 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EIM89176.1 - 0.086 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Imm38 PF15599.1 EIM89176.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 38 FAD_binding_2 PF00890.19 EIM89177.1 - 2.3e-83 280.3 2.6 2.6e-83 280.1 1.8 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM89177.1 - 7.5e-16 57.9 4.7 2.4e-15 56.2 3.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM89177.1 - 5.8e-09 35.8 2.1 7e-09 35.5 0.1 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIM89177.1 - 1.2e-07 31.1 0.7 2.5e-07 30.1 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM89177.1 - 6.9e-07 29.3 2.2 9.7e-06 25.5 0.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM89177.1 - 7.3e-06 24.6 8.2 3.5e-05 22.4 0.3 2.8 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EIM89177.1 - 6.4e-05 21.9 3.2 0.0022 16.8 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIM89177.1 - 0.00011 22.3 0.1 0.00022 21.3 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIM89177.1 - 0.00026 20.1 0.4 0.00069 18.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EIM89177.1 - 0.00032 19.8 3.0 0.00085 18.4 0.4 2.4 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 EIM89177.1 - 0.0031 17.7 0.0 0.0073 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EIM89177.1 - 0.0059 16.1 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EIM89177.1 - 0.01 16.2 0.4 0.01 16.2 0.3 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM89177.1 - 0.012 14.6 0.1 0.025 13.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIM89177.1 - 0.038 12.8 0.2 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EIM89177.1 - 0.07 12.7 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Afi1 PF07792.7 EIM89178.1 - 2.7e-38 131.2 0.0 7.9e-38 129.7 0.0 1.9 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EIM89178.1 - 7.6e-34 115.8 0.0 1.4e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EIM89178.1 - 6.4e-07 28.1 0.0 6.8e-05 21.5 0.0 3.4 3 1 1 4 4 4 1 Transport protein Avl9 Dioxygenase_C PF00775.16 EIM89179.1 - 5e-50 169.3 0.0 6.5e-50 168.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIM89179.1 - 1.6e-16 59.9 0.0 2.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIM89179.1 - 3.8e-05 23.6 0.1 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain FAP PF07174.6 EIM89181.1 - 1.8 7.8 9.6 1.7 7.8 6.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cytochrom_B558a PF05038.8 EIM89181.1 - 2.8 7.5 7.4 3.3 7.2 5.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Kei1 PF08552.6 EIM89182.1 - 0.35 10.5 4.2 0.8 9.3 2.9 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Acyl_transf_3 PF01757.17 EIM89183.1 - 0.0062 15.4 4.9 0.0062 15.4 3.4 1.8 1 1 1 2 2 2 1 Acyltransferase family UPF0104 PF03706.8 EIM89183.1 - 0.0078 15.5 7.4 0.012 14.8 5.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Claudin_2 PF13903.1 EIM89183.1 - 5.7 6.5 11.0 46 3.6 2.0 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2296 PF10058.4 EIM89186.1 - 2.8e-20 71.8 0.1 4.5e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EIM89186.1 - 0.081 12.8 0.3 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EIM89186.1 - 0.37 10.6 1.8 0.41 10.4 0.5 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIM89186.1 - 0.43 10.0 4.7 1.7 8.1 3.3 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain Ycf1 PF05758.7 EIM89187.1 - 0.14 9.8 3.6 0.2 9.3 2.5 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 EIM89187.1 - 0.56 8.0 14.2 1 7.2 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 EIM89187.1 - 0.89 9.2 8.3 0.11 12.1 1.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRP1_N PF06424.7 EIM89187.1 - 9.2 6.5 13.9 2.3 8.5 5.4 2.7 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal RNase_PH PF01138.16 EIM89191.1 - 1.6e-16 60.7 0.1 2.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIM89191.1 - 1.5e-05 24.8 1.8 7.9e-05 22.5 0.1 2.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 DNA_pol_A PF00476.15 EIM89192.1 - 6.2e-93 311.4 0.0 9.8e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.6 EIM89192.1 - 0.013 15.3 0.3 0.045 13.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) ETX_MTX2 PF03318.8 EIM89192.1 - 0.2 11.2 0.1 0.37 10.2 0.1 1.4 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Nop14 PF04147.7 EIM89195.1 - 0.0028 15.6 3.1 0.0036 15.3 2.2 1.0 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.7 EIM89195.1 - 0.21 9.9 6.6 0.25 9.6 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PemK PF02452.12 EIM89195.1 - 0.36 11.0 3.5 0.62 10.2 2.4 1.3 1 0 0 1 1 1 0 PemK-like protein Mucin PF01456.12 EIM89195.1 - 0.39 10.4 22.8 0.65 9.7 15.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein YL1 PF05764.8 EIM89195.1 - 1.1 8.7 8.4 1.6 8.2 5.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.7 EIM89195.1 - 4.4 4.9 9.2 5.4 4.6 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1299 PF06975.6 EIM89196.1 - 2.2 8.2 4.5 6.8 6.6 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1299) Cytochrom_B559 PF00283.14 EIM89198.1 - 9.3 5.6 7.2 1.6 8.0 2.0 1.8 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits DUF3455 PF11937.3 EIM89200.1 - 9.5e-25 87.5 0.0 1.6e-24 86.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) MMR_HSR1 PF01926.18 EIM89201.1 - 7.1e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM89201.1 - 0.0061 15.8 0.2 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIM89201.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MCM PF00493.18 EIM89201.1 - 0.019 13.8 0.1 0.044 12.5 0.0 1.6 1 0 0 1 1 1 0 MCM2/3/5 family AAA_29 PF13555.1 EIM89201.1 - 0.032 13.7 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIM89201.1 - 0.033 15.0 0.4 0.093 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 EIM89201.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.1 EIM89201.1 - 0.077 13.3 1.2 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 EIM89201.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EIM89201.1 - 0.092 12.2 1.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EIM89201.1 - 0.11 12.2 1.2 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family MAP65_ASE1 PF03999.7 EIM89202.1 - 0.0067 15.0 9.4 0.0081 14.8 6.5 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) PRP38_assoc PF12871.2 EIM89202.1 - 0.07 13.6 23.0 0.068 13.7 8.4 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4192 PF13830.1 EIM89202.1 - 0.091 12.3 7.1 0.14 11.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF1777 PF08648.7 EIM89202.1 - 0.17 11.6 23.3 0.034 13.8 10.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) PcfK PF14058.1 EIM89202.1 - 0.76 9.9 5.2 1.3 9.1 3.6 1.4 1 0 0 1 1 1 0 PcfK-like protein TT_ORF1 PF02956.9 EIM89202.1 - 1.4 7.2 9.5 1.8 6.9 6.6 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF1675 PF07897.6 EIM89202.1 - 7.3 6.3 12.0 0.36 10.6 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) PBP1_TM PF14812.1 EIM89202.1 - 9.5 6.6 14.3 4.4 7.6 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 EIM89205.1 - 5.3e-24 84.5 0.1 1.1e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM89205.1 - 1.2e-09 37.9 12.1 2.3e-09 37.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1604 PF07713.8 EIM89206.1 - 1e-07 31.6 0.2 1.2e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) zf-C3HC4_3 PF13920.1 EIM89208.1 - 7.1e-11 41.5 5.3 2.5e-09 36.6 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM89208.1 - 1.9e-06 27.8 4.7 4.3e-06 26.6 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM89208.1 - 0.0001 22.0 3.5 0.0042 16.8 0.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIM89208.1 - 0.00048 19.7 3.1 0.00076 19.0 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM89208.1 - 0.0045 16.6 2.5 0.054 13.2 0.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EIM89208.1 - 2.3 7.8 6.9 0.3 10.6 0.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L18e PF00828.14 EIM89209.1 - 4.8e-35 120.7 0.3 6.5e-35 120.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 EIM89210.1 - 1.5e-22 78.8 0.0 2.1e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIM89210.1 - 1.8e-11 43.0 0.0 2.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 EIM89210.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal NMD3 PF04981.8 EIM89212.1 - 3.4e-75 252.1 0.7 4.4e-75 251.8 0.5 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 EIM89212.1 - 0.0082 15.9 4.6 0.0097 15.7 1.3 2.3 2 1 0 2 2 2 1 Double zinc ribbon DUF1289 PF06945.8 EIM89212.1 - 0.064 12.7 0.1 16 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) NinF PF05810.7 EIM89212.1 - 0.089 12.6 2.2 0.43 10.4 0.5 2.4 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 EIM89212.1 - 0.31 11.0 2.2 1.5 8.7 0.3 2.8 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme TT_ORF2 PF02957.10 EIM89212.1 - 0.36 11.5 0.1 0.36 11.5 0.1 2.8 1 1 1 2 2 2 0 TT viral ORF2 zf-C3HC4_3 PF13920.1 EIM89212.1 - 1.5 8.5 4.9 0.45 10.2 0.2 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF35_N PF12172.3 EIM89212.1 - 5.6 7.0 7.5 9.3 6.2 0.1 3.0 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DPBB_1 PF03330.13 EIM89216.1 - 1.3e-08 34.6 0.8 4.1e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM89216.1 - 0.045 13.4 0.0 0.082 12.5 0.0 1.3 1 1 0 1 1 1 0 Barwin family Adeno_E3_CR2 PF02439.10 EIM89217.1 - 0.0047 16.4 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EIM89217.1 - 0.018 14.3 6.0 0.018 14.3 4.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EIM89217.1 - 0.064 13.6 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 EIM89218.1 - 5.2e-70 235.5 0.0 6e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89218.1 - 3.3e-32 111.5 0.0 7e-32 110.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM89218.1 - 4.4e-06 26.6 0.0 1.2e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIM89218.1 - 0.1 11.3 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lyase_8 PF02278.13 EIM89219.1 - 3.9e-20 72.3 2.8 1.4e-19 70.5 1.9 1.8 1 1 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EIM89219.1 - 1.2e-16 60.5 0.1 1.9e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EIM89219.1 - 0.0021 18.0 0.1 0.0086 16.0 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain PPR_2 PF13041.1 EIM89220.1 - 9e-05 22.3 0.1 3.1 7.8 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 EIM89220.1 - 0.018 14.9 3.5 13 6.0 0.0 4.8 5 0 0 5 5 5 0 PPR repeat SWIRM PF04433.12 EIM89221.1 - 2.8e-34 117.0 0.0 6.5e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EIM89221.1 - 1.6e-10 40.3 2.4 2.9e-10 39.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EIM89221.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIM89221.1 - 1.6e-08 34.4 0.0 3.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chordopox_RPO7 PF05864.7 EIM89221.1 - 0.75 9.9 2.1 6.9 6.8 0.3 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) CDC45 PF02724.9 EIM89221.1 - 1.3 7.0 9.8 0.64 7.9 2.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Peptidase_C50 PF03568.12 EIM89222.1 - 1.3e-97 326.9 0.0 2.3e-97 326.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EIM89222.1 - 8.6e-06 25.6 16.0 0.0012 18.7 0.7 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EIM89222.1 - 0.00017 21.3 3.3 0.16 11.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89222.1 - 0.007 16.0 0.1 15 5.6 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EIM89222.1 - 0.074 13.3 0.4 1.4 9.3 0.0 3.4 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Apc3 PF12895.2 EIM89222.1 - 0.084 13.0 5.0 0.11 12.6 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM89222.1 - 0.16 11.7 3.9 22 5.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89222.1 - 0.36 10.5 9.9 28 4.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DASH_Dam1 PF08653.5 EIM89223.1 - 9.8e-16 57.2 0.1 1.5e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4519 PF15012.1 EIM89223.1 - 0.11 12.4 2.2 0.2 11.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) MRP-L46 PF11788.3 EIM89224.1 - 1.6 9.4 5.3 0.41 11.3 1.0 2.0 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 RNA_pol_N PF01194.12 EIM89225.1 - 5.3e-30 103.2 0.3 6.5e-30 102.9 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF706 PF05153.10 EIM89226.1 - 3.5e-128 426.2 1.6 5.1e-128 425.7 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EIM89226.1 - 0.015 15.2 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 HD domain HAD PF12710.2 EIM89227.1 - 2.4e-15 57.2 0.0 3.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM89227.1 - 7.6e-08 32.7 0.0 4.9e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EIM89227.1 - 1e-06 28.1 0.0 2.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EIM89227.1 - 1.7e-05 25.3 0.0 0.00029 21.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EIM89227.1 - 0.00021 20.6 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Sperm_Ag_HE2 PF05324.8 EIM89227.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sperm antigen HE2 LNS2 PF08235.8 EIM89227.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) zf-C2H2 PF00096.21 EIM89228.1 - 1.1e-05 25.4 1.6 0.0092 16.2 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM89228.1 - 0.00042 20.4 7.0 0.24 11.8 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-UBP PF02148.14 EIM89228.1 - 0.017 15.2 0.3 0.039 14.0 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-TFIIB PF13453.1 EIM89228.1 - 0.024 13.8 0.9 0.05 12.8 0.6 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-C2H2_jaz PF12171.3 EIM89228.1 - 0.12 12.5 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_fiss_reg PF05308.6 EIM89228.1 - 3 7.1 7.6 4.4 6.5 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EIM89228.1 - 9.6 5.3 8.0 15 4.7 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PIP5K PF01504.13 EIM89229.1 - 1.7e-82 276.3 0.0 2.7e-82 275.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase HIT PF01230.18 EIM89230.1 - 1.3e-24 86.5 0.2 1.7e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIM89230.1 - 6.2e-14 52.2 0.1 8.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIM89230.1 - 0.0044 16.6 0.3 0.0082 15.7 0.2 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_S9 PF00326.16 EIM89231.1 - 1.5e-29 102.7 0.0 3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM89231.1 - 5.2e-09 36.0 0.0 1.7e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM89231.1 - 1.6e-08 34.7 0.1 5.4e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIM89231.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EIM89231.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EIM89231.1 - 0.019 14.4 0.0 0.12 11.8 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIM89231.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EIM89231.1 - 0.12 11.8 0.0 0.32 10.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold UDP-g_GGTase PF06427.6 EIM89232.1 - 4.2e-52 176.5 0.0 1.4e-51 174.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EIM89232.1 - 2.7e-07 30.1 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 ADSL_C PF10397.4 EIM89232.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus adh_short PF00106.20 EIM89233.1 - 4.4e-17 62.5 0.0 5.9e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM89233.1 - 0.00048 19.8 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM89235.1 - 4.5e-22 78.7 0.0 7.3e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89235.1 - 2.3e-11 43.9 0.0 3.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EIM89235.1 - 1.9e-07 30.5 0.0 7e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM89235.1 - 9e-05 22.5 0.0 0.0004 20.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM89235.1 - 0.0046 16.4 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM89235.1 - 0.0056 16.3 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1414 PF07208.6 EIM89235.1 - 0.047 13.3 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) SGL PF08450.7 EIM89236.1 - 5.5e-26 91.4 0.0 9.8e-26 90.6 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIM89236.1 - 0.0029 17.5 0.0 0.017 15.1 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EIM89236.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Arylesterase SGL PF08450.7 EIM89237.1 - 2e-26 92.9 0.5 3.4e-26 92.1 0.3 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIM89237.1 - 1.8e-05 24.6 0.1 0.0002 21.3 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EIM89237.1 - 0.004 17.1 0.1 0.022 14.7 0.0 2.2 1 1 0 1 1 1 1 Arylesterase CHAT PF12770.2 EIM89238.1 - 1.6e-25 89.8 0.0 4.6e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 CHAT domain TPR_4 PF07721.9 EIM89238.1 - 0.87 10.2 3.8 0.83 10.2 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NAAA-beta PF15508.1 EIM89239.1 - 0.13 12.6 0.0 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Seryl_tRNA_N PF02403.17 EIM89239.1 - 4.9 7.2 8.8 11 6.1 6.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3819 PF12842.2 EIM89241.1 - 5.4e-52 175.3 0.0 1.1e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Hydrolase_like2 PF13246.1 EIM89241.1 - 2e-11 43.7 0.0 4.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EIM89241.1 - 0.0044 17.4 0.0 0.0092 16.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C48 PF02902.14 EIM89243.1 - 3.3e-14 53.0 1.1 5.6e-14 52.2 0.8 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TBP PF00352.16 EIM89244.1 - 2.3e-37 126.2 3.0 2.6e-23 81.1 0.0 3.3 3 1 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) MULE PF10551.4 EIM89245.1 - 1.5e-06 28.2 0.0 4.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM89245.1 - 2.4e-06 26.9 0.3 4.5e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Pkinase PF00069.20 EIM89246.1 - 6.5e-31 107.4 0.0 8.1e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89246.1 - 5.2e-14 51.9 0.0 6.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM89246.1 - 2e-06 27.6 0.5 0.041 13.6 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EIM89247.1 - 2.4e-12 46.4 4.4 3.8e-12 45.8 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIM89247.1 - 2.7e-10 40.2 0.5 5.1e-10 39.3 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIM89247.1 - 8.7e-08 32.0 3.2 1.4e-07 31.4 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIM89247.1 - 3.6e-07 29.7 1.9 5.3e-07 29.2 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM89247.1 - 5e-07 29.3 3.0 7.8e-07 28.7 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM89247.1 - 8.7e-07 28.5 2.3 1.4e-06 27.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM89247.1 - 0.001 18.8 1.0 0.002 17.9 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_60s PF00428.14 EIM89247.1 - 0.0046 17.3 3.0 0.0046 17.3 2.1 4.4 4 0 0 4 4 3 1 60s Acidic ribosomal protein FANCL_C PF11793.3 EIM89247.1 - 0.0099 15.8 2.5 0.019 14.9 1.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EIM89247.1 - 0.037 14.0 4.4 0.064 13.3 3.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.1 EIM89247.1 - 0.068 12.9 1.8 0.13 12.0 1.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EIM89247.1 - 1.1 8.9 2.5 1.7 8.3 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nucleoplasmin PF03066.10 EIM89247.1 - 6.8 6.2 10.6 0.31 10.5 0.1 2.7 2 0 0 2 2 2 0 Nucleoplasmin Pkinase PF00069.20 EIM89248.1 - 2.4e-29 102.3 0.0 4.2e-29 101.5 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89248.1 - 3.7e-11 42.5 0.0 5.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM89248.1 - 0.00015 21.6 0.0 0.019 14.6 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family TPR_12 PF13424.1 EIM89249.1 - 0.055 13.4 1.9 0.99 9.3 0.6 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM89249.1 - 0.21 11.5 8.8 5.9 6.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CHAT PF12770.2 EIM89250.1 - 1.9e-25 89.5 0.0 5.1e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 CHAT domain TPR_14 PF13428.1 EIM89250.1 - 0.33 11.7 7.8 20 6.1 0.1 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Cnd1 PF12717.2 EIM89251.1 - 8.6e-60 201.6 4.0 9.2e-57 191.7 0.2 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EIM89251.1 - 2.9e-38 131.1 1.4 3.2e-37 127.7 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 EIM89251.1 - 0.012 15.6 1.1 0.86 9.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat DUF2435 PF10363.4 EIM89251.1 - 0.015 15.1 1.1 0.21 11.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) BNIP2 PF12496.3 EIM89251.1 - 2 8.5 9.6 0.048 13.8 1.0 2.6 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF1295 PF06966.7 EIM89252.1 - 2.7e-48 164.3 4.2 4.2e-48 163.6 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIM89252.1 - 1.2e-05 25.3 0.0 5.5e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EIM89252.1 - 0.021 14.6 2.4 0.14 11.8 1.7 2.3 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EIM89252.1 - 0.44 10.7 3.6 0.35 11.1 0.4 2.3 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family E1-E2_ATPase PF00122.15 EIM89254.1 - 5.4e-57 192.4 0.1 5.4e-57 192.4 0.1 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIM89254.1 - 7.2e-24 85.3 0.6 1.9e-23 84.0 0.4 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIM89254.1 - 1.2e-13 50.2 0.1 3e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIM89254.1 - 2.8e-13 50.4 0.1 5.9e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIM89254.1 - 0.00014 21.5 0.0 0.00061 19.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM89254.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pkinase PF00069.20 EIM89255.1 - 1.6e-66 224.1 0.0 4.9e-66 222.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89255.1 - 1.9e-39 135.3 0.0 3.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EIM89255.1 - 2.7e-31 107.3 2.1 3.6e-20 71.6 0.0 3.6 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 EIM89255.1 - 6.2e-08 31.9 1.5 9.8e-08 31.2 0.0 2.1 3 0 0 3 3 3 1 Kinase-like DUF4520 PF15016.1 EIM89255.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Cnd3 PF12719.2 EIM89256.1 - 1.3e-76 257.4 1.3 3.2e-76 256.1 0.6 1.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EIM89256.1 - 3.2e-09 36.9 4.6 2e-06 27.9 0.1 4.6 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EIM89256.1 - 9.4e-06 25.2 1.6 0.97 9.6 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EIM89256.1 - 9.2e-05 22.8 0.0 0.2 12.2 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat DUF2011 PF09428.5 EIM89256.1 - 0.0084 15.9 7.3 0.025 14.4 5.1 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Cnd1 PF12717.2 EIM89257.1 - 4.3e-59 199.3 5.2 8.7e-56 188.5 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EIM89257.1 - 1.2e-34 119.4 1.0 7e-34 116.9 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EIM89257.1 - 3.8e-10 39.9 3.1 0.02 15.1 0.4 5.7 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EIM89257.1 - 0.00024 20.9 6.9 0.55 10.4 0.2 6.5 7 0 0 7 7 7 1 HEAT repeat Adaptin_N PF01602.15 EIM89257.1 - 0.0016 16.8 12.0 0.15 10.3 0.5 4.3 3 2 2 5 5 5 3 Adaptin N terminal region DUF2435 PF10363.4 EIM89257.1 - 0.0081 16.0 6.0 1.8 8.4 0.1 4.3 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) PqqD PF05402.7 EIM89257.1 - 0.013 15.5 0.2 0.31 11.0 0.0 3.2 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) tRNA_NucTran2_2 PF13735.1 EIM89257.1 - 0.014 15.2 0.2 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative HEAT_EZ PF13513.1 EIM89257.1 - 0.37 11.3 4.3 8.8 6.9 0.3 4.4 4 1 1 5 5 5 0 HEAT-like repeat Transket_pyr PF02779.19 EIM89258.1 - 9.2e-61 204.4 0.0 1.4e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIM89258.1 - 2.3e-42 144.7 0.0 5.2e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component DBINO PF13892.1 EIM89258.1 - 0.078 13.0 1.2 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 DNA-binding domain Response_reg PF00072.19 EIM89259.1 - 5.4e-22 77.9 0.6 1e-21 76.9 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain MAPEG PF01124.13 EIM89260.1 - 1.4e-15 57.0 0.8 1.6e-15 56.8 0.6 1.1 1 0 0 1 1 1 1 MAPEG family TMP_2 PF06791.8 EIM89260.1 - 0.064 12.8 0.0 7.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein Benyvirus_P25 PF05744.6 EIM89261.1 - 0.084 12.1 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Benyvirus P25/P26 protein DUF3399 PF11879.3 EIM89261.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3399) SMC_N PF02463.14 EIM89266.1 - 9.2e-62 208.1 0.0 1.6e-61 207.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIM89266.1 - 6e-31 106.8 1.5 1.3e-30 105.8 0.1 2.4 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIM89266.1 - 1.9e-13 51.0 0.3 8e-06 26.0 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIM89266.1 - 5.9e-12 46.3 6.2 5.9e-12 46.3 4.3 6.0 2 2 2 4 4 2 1 AAA domain AAA_29 PF13555.1 EIM89266.1 - 2e-06 27.2 0.0 4.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EIM89266.1 - 0.00099 18.9 0.0 0.0037 17.1 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.6 EIM89266.1 - 0.0015 18.3 11.9 0.0015 18.3 8.3 7.1 3 2 3 7 7 6 2 Autophagy protein 16 (ATG16) FliJ PF02050.11 EIM89266.1 - 0.0017 18.3 8.3 0.0017 18.3 5.7 8.2 4 2 2 7 7 6 1 Flagellar FliJ protein WEMBL PF05701.6 EIM89266.1 - 0.002 16.6 0.2 0.002 16.6 0.1 5.0 3 2 2 5 5 4 2 Weak chloroplast movement under blue light NPV_P10 PF05531.7 EIM89266.1 - 0.026 14.7 24.7 0.041 14.1 0.3 6.6 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EIM89266.1 - 0.027 13.6 25.1 0.042 13.0 0.9 5.8 5 1 3 8 8 8 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 EIM89266.1 - 0.038 13.0 15.1 0.085 11.8 0.0 4.3 4 1 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.22 EIM89266.1 - 0.18 12.0 0.0 0.18 12.0 0.0 5.8 4 3 0 4 4 3 0 ABC transporter Laminin_II PF06009.7 EIM89266.1 - 2.1 8.1 53.3 0.011 15.4 4.9 7.2 4 3 2 7 7 7 0 Laminin Domain II AAA_13 PF13166.1 EIM89266.1 - 9 4.6 76.0 0.54 8.6 10.3 6.5 3 2 2 6 6 6 0 AAA domain Dimer_Tnp_hAT PF05699.9 EIM89267.1 - 2.6e-07 30.1 0.2 3.3e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF818 PF05677.7 EIM89267.1 - 0.12 11.1 0.1 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MutS_III PF05192.13 EIM89268.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.4 1 1 0 1 1 1 0 MutS domain III Aldo_ket_red PF00248.16 EIM89269.1 - 1.3e-46 158.6 0.0 1.6e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM89270.1 - 5.8e-50 169.6 0.0 7.2e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NADHdh_A3 PF14987.1 EIM89277.1 - 0.045 13.6 0.3 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Macoilin PF09726.4 EIM89277.1 - 4.8 5.3 4.7 4.4 5.4 3.3 1.2 1 0 0 1 1 1 0 Transmembrane protein MAPEG PF01124.13 EIM89278.1 - 1.8e-06 27.5 1.3 3.3e-06 26.7 0.9 1.3 1 0 0 1 1 1 1 MAPEG family DUF2158 PF09926.4 EIM89281.1 - 0.018 14.4 0.4 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Ribosomal_S13_N PF08069.7 EIM89282.1 - 2.7e-30 103.9 0.1 6.2e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIM89282.1 - 9.8e-23 79.7 0.1 1.3e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EIM89282.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain Ribosomal_S6e PF01092.14 EIM89283.1 - 3.1e-58 194.9 0.1 5.4e-58 194.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Alpha_L_fucos PF01120.12 EIM89284.1 - 3e-75 253.2 4.0 4.8e-75 252.6 2.8 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EIM89284.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 HMG_box PF00505.14 EIM89286.1 - 2.1e-14 53.4 0.1 2.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM89286.1 - 0.00042 20.6 0.2 0.00062 20.0 0.1 1.3 1 1 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EIM89286.1 - 0.034 13.4 0.1 0.06 12.6 0.0 1.4 1 1 1 2 2 2 0 Mating-type protein MAT alpha 1 DUF1708 PF08101.6 EIM89286.1 - 0.063 12.0 0.0 0.065 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF3712 PF12505.3 EIM89288.1 - 2.5e-156 512.1 82.4 3.1e-24 85.3 0.1 14.4 14 0 0 14 14 14 10 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EIM89288.1 - 2.2e-14 53.6 21.7 0.007 16.7 0.0 10.0 9 0 0 9 9 9 5 Late embryogenesis abundant protein Chlorosome_CsmC PF11098.3 EIM89288.1 - 0.0002 21.1 17.7 0.00081 19.1 12.3 2.1 1 0 0 1 1 1 1 Chlorosome envelope protein C TC1 PF15063.1 EIM89288.1 - 0.0012 18.2 0.0 1.5 8.4 0.0 3.6 4 0 0 4 4 4 1 Thyroid cancer protein 1 DUF1480 PF07351.8 EIM89288.1 - 1.6 8.7 2.7 55 3.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1480) SseC PF04888.7 EIM89288.1 - 1.8 7.8 22.9 3.7 6.8 15.8 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family tRNA-synt_1d PF00750.14 EIM89289.1 - 4.2e-81 272.5 1.3 5.4e-81 272.1 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EIM89289.1 - 1.4e-20 73.4 0.0 3e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain UPF0220 PF05255.6 EIM89291.1 - 5.2e-52 175.4 0.0 6.8e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) dsrm PF00035.20 EIM89292.1 - 2.2e-05 24.9 0.0 3.8e-05 24.1 0.0 1.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif But2 PF09792.4 EIM89294.1 - 0.025 14.3 0.0 0.31 10.7 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EIM89295.1 - 7.3e-21 74.8 1.1 1.1e-20 74.2 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RRM_1 PF00076.17 EIM89297.1 - 1.9e-12 46.6 0.0 3.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89297.1 - 4.2e-10 39.4 0.0 7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIM89297.1 - 4.7e-06 26.9 0.3 8.5e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EIM89297.1 - 0.0061 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPBB_1 PF03330.13 EIM89298.1 - 1.9e-06 27.7 0.1 4.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM89298.1 - 0.086 12.5 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Barwin family Cys_rich_CPXG PF14255.1 EIM89298.1 - 0.15 11.9 0.3 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG HLH PF00010.21 EIM89300.1 - 7.6e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DPBB_1 PF03330.13 EIM89302.1 - 3.7e-06 26.8 0.2 1.6e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM89302.1 - 0.0037 16.9 0.0 0.007 16.0 0.0 1.5 1 1 0 1 1 1 1 Barwin family FAD_binding_3 PF01494.14 EIM89303.1 - 3.4e-80 269.7 0.0 4.7e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM89303.1 - 1.6e-08 33.8 0.0 5.9e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM89303.1 - 1.5e-06 28.4 0.4 0.014 15.7 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM89303.1 - 0.00022 21.1 0.1 0.0029 17.5 0.1 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM89303.1 - 0.00026 19.9 0.6 0.0017 17.2 0.0 2.1 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM89303.1 - 0.00084 19.4 0.0 0.0037 17.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM89303.1 - 0.00092 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM89303.1 - 0.00094 18.3 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIM89303.1 - 0.0062 15.0 0.2 0.03 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIM89303.1 - 0.013 14.5 0.1 0.042 12.9 0.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM89303.1 - 0.067 12.9 0.3 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM89303.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM89303.1 - 0.08 11.5 0.0 0.18 10.4 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.19 EIM89303.1 - 0.085 11.9 0.4 13 4.6 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EIM89303.1 - 0.11 12.5 0.1 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.11 EIM89304.1 - 7.1e-21 74.2 44.5 4.6e-17 61.7 9.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily N_methyl PF07963.7 EIM89304.1 - 1.6 8.6 5.1 0.39 10.5 0.3 2.6 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif DUF1228 PF06779.9 EIM89304.1 - 2 8.4 10.9 0.77 9.8 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EIM89305.1 - 3e-17 62.3 35.4 7.1e-10 38.1 4.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.4 EIM89305.1 - 0.079 13.1 4.0 2.2 8.5 0.0 3.5 4 0 0 4 4 4 0 Presenilin enhancer-2 subunit of gamma secretase DUF485 PF04341.7 EIM89305.1 - 0.22 11.2 4.6 1.3 8.7 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF1228 PF06779.9 EIM89305.1 - 7 6.7 10.3 2.1 8.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) SRP40_C PF05022.7 EIM89306.1 - 0.016 15.6 0.2 0.016 15.6 0.2 1.8 2 0 0 2 2 2 0 SRP40, C-terminal domain Daxx PF03344.10 EIM89306.1 - 0.43 8.9 14.7 0.55 8.6 10.2 1.3 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 EIM89306.1 - 1.2 8.9 11.6 1.8 8.3 8.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VID27 PF08553.5 EIM89306.1 - 4.2 5.4 10.7 4.9 5.2 7.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Xin PF08043.7 EIM89309.1 - 0.13 11.9 0.9 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 Xin repeat 6PF2K PF01591.13 EIM89310.1 - 1.3e-62 210.8 0.0 2e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIM89310.1 - 1.6e-23 83.5 0.0 4.6e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIM89310.1 - 6.8e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIM89310.1 - 0.00013 21.2 0.0 0.00027 20.2 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EIM89310.1 - 0.00029 21.6 0.7 0.0019 18.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM89310.1 - 0.031 13.3 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Peripla_BP_4 PF13407.1 EIM89310.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Abhydrolase_5 PF12695.2 EIM89311.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM89311.1 - 0.00046 20.1 0.0 0.00059 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EIM89312.1 - 9.9e-68 228.7 25.4 1.7e-67 227.9 17.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM89312.1 - 2.8e-27 95.3 51.6 2e-24 85.9 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM89312.1 - 2e-05 23.0 4.4 3.9e-05 22.0 3.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.2 EIM89313.1 - 0.0084 15.8 0.2 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3762 PF12591.3 EIM89313.1 - 0.04 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) LRR_4 PF12799.2 EIM89313.1 - 0.46 10.1 2.4 16 5.2 0.0 3.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIM89314.1 - 3.5 8.2 6.3 1.1e+02 3.6 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EIM89315.1 - 0.14 11.7 1.5 30 4.3 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM89316.1 - 0.0013 18.4 2.0 0.0033 17.1 0.5 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIM89316.1 - 0.026 14.1 5.0 1.5 8.5 0.1 4.3 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM89316.1 - 0.57 9.9 4.0 8.6 6.2 0.1 4.0 5 0 0 5 5 5 0 Leucine rich repeat CAF-1_p150 PF11600.3 EIM89317.1 - 0.011 15.1 1.4 0.011 15.1 1.0 3.4 5 0 0 5 5 5 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4207 PF13904.1 EIM89317.1 - 0.025 13.9 1.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) PRP38_assoc PF12871.2 EIM89317.1 - 0.54 10.8 39.0 0.048 14.1 11.3 3.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term LRR_4 PF12799.2 EIM89318.1 - 0.035 13.7 1.6 16 5.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM89319.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89319.1 - 0.0034 17.0 0.1 0.012 15.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain MFS_2 PF13347.1 EIM89320.1 - 0.029 12.7 15.2 0.0061 15.0 7.6 1.7 1 1 1 2 2 2 0 MFS/sugar transport protein PsbN PF02468.10 EIM89320.1 - 6.8 6.3 6.2 29 4.3 0.1 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) FixQ PF05545.6 EIM89320.1 - 8.6 6.0 6.8 0.42 10.2 0.1 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TraQ PF09679.5 EIM89321.1 - 0.02 14.8 1.9 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF2768 PF10966.3 EIM89321.1 - 0.024 14.7 2.4 0.063 13.4 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) PEN-2 PF10251.4 EIM89321.1 - 1.1 9.5 3.9 0.43 10.8 0.4 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Ifi-6-16 PF06140.8 EIM89324.1 - 0.84 9.4 24.7 0.41 10.4 15.3 1.9 2 1 0 2 2 2 0 Interferon-induced 6-16 family NmrA PF05368.8 EIM89325.1 - 6.5e-19 68.1 0.0 8.6e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM89325.1 - 1.5e-11 44.6 0.0 5.1e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM89325.1 - 0.022 13.4 0.0 0.21 10.2 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Band_7 PF01145.20 EIM89326.1 - 5.2e-07 29.7 0.0 5.2e-07 29.7 0.0 2.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family Arginase PF00491.16 EIM89327.1 - 7.3e-85 284.6 0.0 9.3e-85 284.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family KCNQ_channel PF03520.9 EIM89327.1 - 0.063 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel UPF0489 PF12640.2 EIM89327.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.13 EIM89328.1 - 1.7e-46 157.8 26.0 6.1e-29 100.7 5.4 2.5 3 0 0 3 3 3 2 MatE Sugar_tr PF00083.19 EIM89329.1 - 3.9e-96 322.3 19.6 4.5e-96 322.1 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM89329.1 - 1.5e-24 86.4 66.7 2.4e-19 69.2 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIM89329.1 - 0.0017 16.5 1.5 0.0033 15.5 1.0 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EIM89330.1 - 1.9e-19 69.5 25.4 3.6e-19 68.7 17.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EIM89330.1 - 2.6e-05 24.1 7.6 0.0051 16.8 0.7 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 EIM89330.1 - 0.00059 19.5 0.4 0.00059 19.5 0.3 2.3 2 0 0 2 2 2 1 MFS_1 like family Hydantoinase_B PF02538.9 EIM89331.1 - 1e-169 565.2 1.6 1.4e-169 564.7 1.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EIM89331.1 - 6e-91 304.5 2.6 1.2e-90 303.5 0.0 2.6 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIM89331.1 - 1.3e-56 190.8 1.9 4.4e-55 185.9 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Aa_trans PF01490.13 EIM89333.1 - 5.6e-39 133.7 38.9 1.2e-38 132.6 26.9 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CHAT PF12770.2 EIM89334.1 - 2.5e-28 99.0 0.0 6.1e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Transpep_BrtH PF14399.1 EIM89334.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase PLC-beta_C PF08703.5 EIM89334.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 PLC-beta C terminal DUF1863 PF08937.6 EIM89335.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) CHAT PF12770.2 EIM89336.1 - 0.0032 16.6 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 CHAT domain DUF3129 PF11327.3 EIM89337.1 - 0.047 13.5 0.2 0.079 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3129) Ank_2 PF12796.2 EIM89338.1 - 8.3e-31 106.1 3.0 1.3e-17 63.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM89338.1 - 5.2e-30 101.7 5.6 3.2e-07 29.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EIM89338.1 - 1.9e-24 85.5 3.9 1.2e-07 32.0 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM89338.1 - 6.1e-21 72.4 1.9 0.00014 21.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EIM89338.1 - 2.3e-18 65.7 2.6 5.1e-06 26.5 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) YajC PF02699.10 EIM89338.1 - 0.016 14.9 2.5 3 7.6 0.0 3.5 2 1 2 4 4 4 0 Preprotein translocase subunit HMG_box PF00505.14 EIM89339.1 - 9.4e-10 38.6 0.3 2.9e-09 37.0 0.2 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box 2OG-Fe_Oxy_2 PF10014.4 EIM89341.1 - 0.064 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase Nucleoplasmin PF03066.10 EIM89342.1 - 0.26 10.8 3.0 0.37 10.2 2.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIM89342.1 - 0.27 11.5 4.0 0.4 10.9 2.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_C14 PF00656.17 EIM89343.1 - 4.6e-23 82.1 0.0 2.1e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Caspase domain HhH-GPD PF00730.20 EIM89344.1 - 8.7e-12 45.2 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIM89344.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Peptidase_C14 PF00656.17 EIM89345.1 - 4.7e-30 105.0 0.0 4.7e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ABC_membrane PF00664.18 EIM89346.1 - 6.5e-45 153.6 29.1 3.4e-25 89.0 1.9 4.0 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM89346.1 - 1.2e-42 145.4 0.0 3.8e-25 88.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIM89346.1 - 4.7e-11 42.3 3.8 0.0037 16.5 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM89346.1 - 6.4e-11 42.7 1.1 0.046 13.6 0.0 4.4 2 2 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EIM89346.1 - 1.5e-07 31.0 0.0 0.012 14.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIM89346.1 - 6.6e-07 29.4 2.3 0.0054 16.7 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EIM89346.1 - 2.7e-06 27.8 2.0 0.00022 21.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIM89346.1 - 6.5e-06 25.2 0.0 0.0027 16.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EIM89346.1 - 1e-05 24.9 1.1 0.024 14.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIM89346.1 - 0.00039 21.2 1.1 2.2 9.1 0.3 3.3 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EIM89346.1 - 0.00072 19.0 0.2 0.52 9.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EIM89346.1 - 0.00073 19.2 0.7 0.69 9.6 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EIM89346.1 - 0.0012 18.7 0.7 0.045 13.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EIM89346.1 - 0.0012 18.3 0.5 0.78 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EIM89346.1 - 0.0018 18.5 0.1 2.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM89346.1 - 0.0019 18.3 1.2 0.3 11.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EIM89346.1 - 0.0024 18.3 0.0 3.3 8.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EIM89346.1 - 0.0027 17.6 0.3 0.68 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EIM89346.1 - 0.004 16.9 0.1 0.28 10.8 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase DUF258 PF03193.11 EIM89346.1 - 0.0069 15.5 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EIM89346.1 - 0.009 15.7 0.0 0.3 10.8 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 EIM89346.1 - 0.028 13.0 0.1 0.16 10.6 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.9 EIM89346.1 - 0.03 14.0 0.5 26 4.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIM89346.1 - 0.033 13.2 0.1 2.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EIM89346.1 - 0.042 12.4 0.4 5.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 EIM89346.1 - 0.059 13.1 0.7 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EIM89346.1 - 0.072 12.7 0.4 3.7 7.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 EIM89346.1 - 0.078 12.7 0.0 27 4.5 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.7 EIM89346.1 - 0.09 12.0 1.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 EIM89346.1 - 0.12 12.2 0.1 6 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EIM89346.1 - 0.17 11.2 2.1 0.98 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HMG_box PF00505.14 EIM89350.1 - 7e-10 39.0 3.9 9.3e-10 38.6 2.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM89350.1 - 4.6e-08 33.3 2.7 5.9e-08 32.9 1.8 1.2 1 0 0 1 1 1 1 HMG-box domain G2F PF07474.7 EIM89351.1 - 0.095 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 G2F domain Neogenin_C PF06583.7 EIM89351.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Neogenin C-terminus DDE_3 PF13358.1 EIM89353.1 - 4.4e-09 36.2 0.1 7.1e-08 32.3 0.1 2.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Exonuc_V_gamma PF04257.9 EIM89353.1 - 0.065 11.2 0.0 0.12 10.3 0.0 1.3 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit zf-ribbon_3 PF13248.1 EIM89354.1 - 1.2 8.4 12.0 5.5 6.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ArfGap PF01412.13 EIM89354.1 - 3 7.6 10.6 5.2 6.8 7.3 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Zn_Tnp_IS91 PF14319.1 EIM89354.1 - 6.5 6.3 18.9 0.092 12.2 5.9 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain RVT_1 PF00078.22 EIM89356.1 - 2.6e-06 26.9 0.0 2.9e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIM89358.1 - 0.00027 21.2 0.1 0.00048 20.4 0.0 1.4 2 0 0 2 2 2 1 RNase H ABC_tran PF00005.22 EIM89359.1 - 7.6e-43 146.1 0.0 5.2e-25 88.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM89359.1 - 4.3e-38 131.2 26.4 2.3e-21 76.4 4.4 3.3 3 1 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIM89359.1 - 2.2e-12 46.6 2.5 0.00028 20.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM89359.1 - 4.1e-11 43.3 2.9 3.6e-05 23.8 0.0 4.8 3 2 1 4 4 3 1 AAA domain AAA_23 PF13476.1 EIM89359.1 - 1.8e-07 31.6 1.4 3.3e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM89359.1 - 1.1e-06 28.2 0.1 0.026 13.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIM89359.1 - 1.7e-06 28.1 0.1 0.02 14.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIM89359.1 - 2.3e-06 27.0 0.2 0.018 14.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EIM89359.1 - 1e-05 24.6 0.0 0.0097 14.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 EIM89359.1 - 0.00065 19.4 0.8 0.4 10.3 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EIM89359.1 - 0.00069 19.1 0.1 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EIM89359.1 - 0.00077 20.2 0.5 3.1 8.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EIM89359.1 - 0.0019 17.9 0.2 0.079 12.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EIM89359.1 - 0.0022 18.2 0.1 3.6 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIM89359.1 - 0.0032 17.9 0.1 5.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EIM89359.1 - 0.0035 17.4 0.5 1.2 9.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 EIM89359.1 - 0.0035 16.0 0.3 0.017 13.7 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF258 PF03193.11 EIM89359.1 - 0.0055 15.9 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIM89359.1 - 0.0071 16.2 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 EIM89359.1 - 0.0077 16.0 1.8 0.035 13.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EIM89359.1 - 0.015 14.9 0.1 23 4.6 0.0 4.1 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EIM89359.1 - 0.021 14.2 2.3 3.5 6.9 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EIM89359.1 - 0.031 13.3 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 EIM89359.1 - 0.039 13.7 0.0 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EIM89359.1 - 0.041 13.2 0.0 10 5.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 EIM89359.1 - 0.044 12.3 0.5 4.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GvpD PF07088.6 EIM89359.1 - 0.052 11.8 0.4 0.13 10.5 0.0 1.7 2 0 0 2 2 2 0 GvpD gas vesicle protein Pox_A32 PF04665.7 EIM89359.1 - 0.071 12.3 0.5 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 EIM89359.1 - 0.078 12.6 0.2 12 5.5 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EIM89359.1 - 0.078 12.7 0.0 2.2 8.0 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain NACHT PF05729.7 EIM89359.1 - 0.082 12.5 0.6 3.9 7.0 0.0 2.7 3 0 0 3 3 2 0 NACHT domain DEAD PF00270.24 EIM89359.1 - 0.092 12.2 0.0 21 4.5 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.14 EIM89359.1 - 0.098 12.0 1.5 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 EIM89359.1 - 0.13 11.4 0.7 17 4.5 0.1 3.5 3 1 1 4 4 4 0 PhoH-like protein AAA_30 PF13604.1 EIM89359.1 - 0.17 11.4 0.0 15 5.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Smg4_UPF3 PF03467.10 EIM89359.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Smg-4/UPF3 family RNA12 PF10443.4 EIM89359.1 - 0.33 9.3 0.2 0.7 8.3 0.0 1.5 2 0 0 2 2 2 0 RNA12 protein AAA_24 PF13479.1 EIM89359.1 - 1 8.8 2.8 2.1 7.8 0.1 2.4 3 0 0 3 3 2 0 AAA domain Peptidase_M28 PF04389.12 EIM89360.1 - 5.6e-22 78.3 0.8 1e-21 77.4 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIM89360.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EIM89360.1 - 0.012 14.4 0.0 0.032 13.0 0.0 1.7 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase Peptidase_C14 PF00656.17 EIM89361.1 - 0.027 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF1148 PF06618.6 EIM89361.1 - 0.087 12.7 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Peptidase_C14 PF00656.17 EIM89362.1 - 5.5e-25 88.4 0.0 7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain TPR_10 PF13374.1 EIM89363.1 - 4.2e-41 137.7 13.4 1.6e-12 46.8 0.0 6.3 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIM89363.1 - 6.3e-32 109.3 0.7 8.8e-15 54.4 0.0 4.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIM89363.1 - 1.6e-08 34.0 0.3 0.53 10.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 EIM89363.1 - 1.7e-08 33.6 0.0 4.6e-07 28.9 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain TPR_7 PF13176.1 EIM89363.1 - 4.3e-08 32.3 5.7 0.019 14.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89363.1 - 5.3e-06 25.9 2.2 4.1 7.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89363.1 - 2.3e-05 23.7 1.2 0.73 9.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89363.1 - 4.1e-05 23.1 0.7 0.072 12.7 0.0 4.0 2 2 1 3 3 3 1 TPR repeat TPR_14 PF13428.1 EIM89363.1 - 8.4e-05 22.8 3.2 11 6.9 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NACHT PF05729.7 EIM89363.1 - 0.00014 21.5 0.0 0.00046 19.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.9 EIM89363.1 - 0.0015 18.8 9.2 1.3 9.6 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89363.1 - 0.0025 18.1 0.4 8 6.8 0.0 4.9 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89363.1 - 0.02 14.6 0.6 35 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 EIM89363.1 - 0.027 14.6 0.0 0.087 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Patatin PF01734.17 EIM89364.1 - 2.4e-27 96.1 0.1 4e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Polyketide_cyc2 PF10604.4 EIM89368.1 - 2.2e-08 34.3 0.1 1.5e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EIM89368.1 - 3.8e-06 26.9 0.0 5.3e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_C14 PF00656.17 EIM89369.1 - 7.1e-41 140.5 0.0 1.2e-40 139.8 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIM89370.1 - 4e-44 151.1 0.0 6.2e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM89370.1 - 0.12 12.2 0.0 0.52 10.1 0.0 2.0 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 EIM89371.1 - 1.5e-19 70.6 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EIM89371.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain PIG-L PF02585.12 EIM89371.1 - 0.1 13.0 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Peptidase_C14 PF00656.17 EIM89372.1 - 6.9e-16 58.6 0.1 1.4e-15 57.7 0.1 1.4 1 1 0 1 1 1 1 Caspase domain 2OG-FeII_Oxy_3 PF13640.1 EIM89373.1 - 4.5e-05 23.8 0.1 0.00012 22.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM89373.1 - 0.0024 18.1 0.1 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_7 PF13504.1 EIM89374.1 - 0.0021 17.9 0.3 96 3.9 0.0 5.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EIM89374.1 - 0.069 13.2 0.9 35 4.8 0.0 4.5 6 0 0 6 6 6 0 Leucine Rich repeat F-box-like PF12937.2 EIM89375.1 - 4.2e-08 32.7 0.3 1.2e-07 31.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIM89377.1 - 1.8e-27 94.1 10.4 1.2e-09 37.7 0.3 5.5 6 1 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIM89377.1 - 5.8e-06 26.0 0.0 0.88 9.3 0.0 3.7 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 EIM89377.1 - 0.023 14.3 0.0 1.7 8.2 0.0 3.2 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal GP46 PF07409.7 EIM89377.1 - 0.048 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage protein GP46 zf-MYND PF01753.13 EIM89379.1 - 1.1e-06 28.4 11.4 2.2e-06 27.4 7.9 1.5 1 0 0 1 1 1 1 MYND finger Complex1_51K PF01512.12 EIM89380.1 - 7.5e-48 162.0 0.0 1.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EIM89380.1 - 5.4e-20 70.2 0.5 5.4e-20 70.2 0.4 2.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EIM89380.1 - 2.2e-08 33.8 0.0 8e-08 32.0 0.0 2.1 1 0 0 1 1 1 1 SLBB domain NAD_binding_4 PF07993.7 EIM89381.1 - 7.5e-32 110.2 0.0 1.4e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM89381.1 - 4.5e-23 81.3 0.0 7.3e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM89381.1 - 1e-10 41.4 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM89381.1 - 0.00016 21.8 0.1 0.001 19.2 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EIM89381.1 - 0.00036 19.5 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EIM89381.1 - 0.0029 17.5 0.0 0.0087 15.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM89381.1 - 0.0031 17.1 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIM89381.1 - 0.03 13.0 0.0 0.16 10.6 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M20 PF01546.23 EIM89384.1 - 1.2e-31 109.7 0.0 1.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM89384.1 - 7.9e-14 51.3 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_6 PF12697.2 EIM89385.1 - 9.3e-27 94.3 0.8 1.1e-26 94.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89385.1 - 9.1e-16 58.1 0.0 1.7e-15 57.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89385.1 - 8.5e-11 41.8 0.1 4e-10 39.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.3 EIM89385.1 - 0.0033 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) PGAP1 PF07819.8 EIM89385.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 EIM89385.1 - 0.044 13.3 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S15 PF02129.13 EIM89385.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EIM89386.1 - 8.7e-28 97.7 0.1 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89386.1 - 1.5e-18 67.1 0.0 1.9e-17 63.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89386.1 - 2.7e-10 40.1 0.0 6.1e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM89386.1 - 0.0001 22.6 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.13 EIM89386.1 - 0.032 13.6 0.1 0.076 12.4 0.1 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 EIM89386.1 - 0.04 13.5 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 EIM89386.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 EIM89386.1 - 0.05 13.1 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EIM89386.1 - 0.071 12.3 0.0 8 5.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIM89387.1 - 2.1e-22 80.1 0.8 2.8e-22 79.7 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM89387.1 - 1.5e-18 66.9 0.0 2.2e-18 66.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIM89387.1 - 3.9e-15 55.4 0.1 1.1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EIM89387.1 - 1e-07 31.3 0.3 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EIM89387.1 - 1e-05 25.2 0.1 2.5e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EIM89387.1 - 0.00059 19.1 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EIM89387.1 - 0.0018 16.8 0.0 0.0057 15.2 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DUF900 PF05990.7 EIM89387.1 - 0.0044 16.3 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.2 EIM89387.1 - 0.0058 15.5 0.0 0.016 14.1 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 EIM89387.1 - 0.0081 14.8 0.0 0.016 13.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) LCAT PF02450.10 EIM89387.1 - 0.021 13.8 0.0 0.078 11.9 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EIM89387.1 - 0.029 13.7 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EIM89387.1 - 0.05 13.1 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.3 EIM89387.1 - 0.055 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF1749 PF08538.5 EIM89387.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EIM89387.1 - 0.18 11.3 0.1 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein SUR7 PF06687.7 EIM89388.1 - 2.8e-10 40.1 15.8 3.2e-09 36.6 10.9 2.0 1 1 0 1 1 1 1 SUR7/PalI family DUF3068 PF11271.3 EIM89388.1 - 3 6.7 6.1 0.12 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3068) Claudin_2 PF13903.1 EIM89388.1 - 3.7 7.2 12.9 0.2 11.3 2.9 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EIM89389.1 - 4e-17 62.4 5.3 6e-17 61.9 3.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.18 EIM89389.1 - 0.2 11.4 10.7 0.022 14.5 2.9 2.2 2 0 0 2 2 2 0 Membrane-associating domain DUF3561 PF12084.3 EIM89389.1 - 1.3 8.8 6.4 0.16 11.8 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) DUF4064 PF13273.1 EIM89389.1 - 2.9 8.0 11.2 2 8.5 3.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3796 PF12676.2 EIM89389.1 - 3 8.0 5.5 0.41 10.8 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) zf-MYND PF01753.13 EIM89390.1 - 7.6e-12 44.8 9.3 7.6e-12 44.8 6.5 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EIM89390.1 - 0.33 10.8 10.7 0.046 13.5 2.6 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ubiquitin PF00240.18 EIM89391.1 - 8.1e-18 63.5 0.1 1.1e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM89391.1 - 3.2e-07 29.9 0.2 4.4e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIM89391.1 - 0.00016 21.8 0.0 0.00055 20.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EIM89391.1 - 0.0024 18.0 0.0 0.0034 17.5 0.0 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain SH3BGR PF04908.10 EIM89391.1 - 0.048 13.6 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein zf-CCHC PF00098.18 EIM89392.1 - 4.4e-05 23.2 3.5 0.00012 21.8 2.5 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EIM89392.1 - 0.0036 17.3 0.4 0.011 15.7 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EIM89392.1 - 0.18 11.4 1.7 0.41 10.3 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_6 PF12697.2 EIM89396.1 - 2.7e-17 63.3 0.0 7.5e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89396.1 - 5.6e-08 32.6 0.1 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89396.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 EIM89397.1 - 7.3e-16 58.6 0.8 1.5e-15 57.6 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM89397.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EIM89397.1 - 0.086 11.9 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DUF3561 PF12084.3 EIM89398.1 - 0.027 14.3 1.5 0.053 13.3 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) DUF2207 PF09972.4 EIM89398.1 - 0.13 10.8 0.9 0.16 10.5 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tic20 PF09685.5 EIM89398.1 - 0.28 11.1 6.2 0.47 10.4 4.3 1.3 1 0 0 1 1 1 0 Tic20-like protein TrbL PF04610.9 EIM89398.1 - 0.35 10.5 10.1 0.6 9.7 7.0 1.4 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein AA_permease PF00324.16 EIM89399.1 - 7.2e-116 387.3 43.7 8.2e-116 387.1 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM89399.1 - 1.2e-34 119.5 47.1 1.5e-34 119.2 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease DAHP_synth_2 PF01474.11 EIM89401.1 - 1.8e-177 590.1 0.0 2e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF3702 PF12486.3 EIM89403.1 - 0.0078 15.9 1.7 0.037 13.7 1.1 2.0 1 1 0 1 1 1 1 ImpA domain protein DUF2031 PF09592.5 EIM89403.1 - 0.02 14.0 0.6 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) CHAT PF12770.2 EIM89404.1 - 3.3e-37 128.1 0.1 5.1e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EIM89404.1 - 1.9e-31 107.4 0.0 0.014 14.9 0.0 14.3 6 5 11 17 17 17 8 TPR repeat TPR_12 PF13424.1 EIM89404.1 - 3.9e-29 100.4 0.1 0.011 15.6 0.0 14.6 5 3 9 15 15 15 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89404.1 - 6.4e-29 97.5 0.0 1.4 9.0 0.0 16.2 17 1 0 17 17 17 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89404.1 - 7.6e-17 60.3 13.2 4.1 8.2 0.0 14.3 16 1 1 17 17 13 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89404.1 - 6.3e-13 47.5 0.0 28 4.7 0.0 13.5 17 0 0 17 17 15 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89404.1 - 1.8e-07 30.4 0.0 73 3.2 0.0 10.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89404.1 - 1.7e-06 28.5 7.4 12 6.6 0.0 9.7 11 1 0 11 11 9 0 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 EIM89404.1 - 4.1e-06 26.9 19.7 10 6.1 0.0 12.0 5 3 7 13 13 12 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_19 PF14559.1 EIM89404.1 - 2.7e-05 24.4 4.1 17 5.8 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4164 PF13747.1 EIM89404.1 - 0.00057 19.9 5.0 68 3.6 0.0 8.7 9 0 0 9 9 9 0 Domain of unknown function (DUF4164) Erythro-docking PF09277.6 EIM89404.1 - 0.0026 17.4 19.3 0.49 10.1 0.0 7.7 6 1 2 8 8 7 2 Erythronolide synthase, docking OST-HTH PF12872.2 EIM89404.1 - 0.038 13.8 0.0 5.7 6.8 0.0 4.0 4 0 0 4 4 4 0 OST-HTH/LOTUS domain DUF1785 PF08699.5 EIM89404.1 - 0.17 11.3 0.4 35 3.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1785) Mitofilin PF09731.4 EIM89405.1 - 9.4 4.7 6.6 12 4.3 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4611 PF15387.1 EIM89406.1 - 0.19 11.8 1.7 0.26 11.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Chitin_bind_3 PF03067.10 EIM89408.1 - 7.2e-11 42.6 3.5 8.5e-11 42.4 2.4 1.1 1 0 0 1 1 1 1 Chitin binding domain CARDB PF07705.6 EIM89408.1 - 0.004 17.1 1.3 0.017 15.1 0.8 2.0 1 1 1 2 2 2 1 CARDB Glyco_hydro_61 PF03443.9 EIM89408.1 - 0.0047 16.7 0.3 0.21 11.3 0.0 2.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 61 zf-MYND PF01753.13 EIM89409.1 - 5.3e-09 35.8 9.6 1.1e-08 34.8 6.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C2H2 PF00096.21 EIM89410.1 - 5e-05 23.3 1.4 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM89410.1 - 0.00093 19.3 2.4 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EIM89410.1 - 0.12 12.5 1.6 6.3 7.0 1.7 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIM89410.1 - 0.14 12.3 8.7 0.17 12.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LGFP PF08310.6 EIM89411.1 - 0.1 12.2 0.1 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 LGFP repeat adh_short PF00106.20 EIM89414.1 - 3.4e-28 98.6 0.0 4.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89414.1 - 1.2e-11 44.8 0.0 2.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89414.1 - 2.2e-08 33.9 0.0 5.2e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM89414.1 - 0.00024 21.1 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIM89414.1 - 0.00049 19.8 0.1 0.00092 18.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GidB PF02527.10 EIM89414.1 - 0.003 16.7 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NAD_binding_10 PF13460.1 EIM89415.1 - 0.00018 21.5 0.0 0.00041 20.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM89415.1 - 0.044 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 EIM89415.1 - 0.055 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3735 PF12537.3 EIM89417.1 - 0.091 12.8 2.5 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) DUF3450 PF11932.3 EIM89419.1 - 1.5 8.0 17.6 0.032 13.5 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) CBM_19 PF03427.8 EIM89421.1 - 0.16 11.8 3.0 0.21 11.3 2.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Aa_trans PF01490.13 EIM89422.1 - 3.2e-26 91.7 25.9 3.7e-25 88.2 17.9 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4420 PF14390.1 EIM89424.1 - 0.16 10.7 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) Snapin_Pallidin PF14712.1 EIM89426.1 - 0.7 10.2 3.9 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Agouti PF05039.7 EIM89427.1 - 0.017 15.4 3.1 0.019 15.3 2.2 1.2 1 0 0 1 1 1 0 Agouti protein Dickkopf_N PF04706.7 EIM89427.1 - 0.034 14.3 2.3 0.046 13.8 1.6 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_19 PF08088.7 EIM89427.1 - 0.034 14.0 4.2 0.05 13.5 2.9 1.2 1 0 0 1 1 1 0 Conotoxin I-superfamily Toxin_12 PF07740.7 EIM89427.1 - 0.04 14.3 5.5 0.059 13.8 3.8 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin PF02950.12 EIM89427.1 - 0.21 12.4 5.5 0.29 11.9 3.8 1.6 1 1 0 1 1 1 0 Conotoxin Toxin_27 PF08099.6 EIM89427.1 - 1.4 8.8 4.4 2.3 8.2 3.0 1.3 1 0 0 1 1 1 0 Scorpion calcine family DUF479 PF04336.7 EIM89430.1 - 0.12 12.5 0.2 0.44 10.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF479 zf-MYND PF01753.13 EIM89431.1 - 7.7e-08 32.0 15.6 1.9e-07 30.8 10.8 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EIM89432.1 - 3.8e-08 32.9 0.1 9.1e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM89432.1 - 1.6 8.4 4.0 3.9 7.2 0.0 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Trypan_PARP PF05887.6 EIM89435.1 - 0.0088 15.8 7.3 0.0088 15.8 5.1 5.1 4 2 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Sec34 PF04136.10 EIM89437.1 - 0.026 14.2 0.0 0.029 14.0 0.0 1.0 1 0 0 1 1 1 0 Sec34-like family Glyco_hydro_3 PF00933.16 EIM89440.1 - 7e-55 186.1 0.0 1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM89440.1 - 4.1e-48 163.8 0.0 5.8e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM89440.1 - 1.7e-11 43.8 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cu-oxidase PF00394.17 EIM89441.1 - 5.6e-47 159.5 0.1 1.2e-43 148.7 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM89441.1 - 4.1e-38 129.9 6.4 5.2e-36 123.1 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM89441.1 - 6.4e-37 125.8 0.4 1.2e-35 121.8 0.2 2.8 3 0 0 3 3 3 1 Multicopper oxidase HNH_2 PF13391.1 EIM89442.1 - 2.5e-06 27.1 0.1 6.5e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease SRF-TF PF00319.13 EIM89445.1 - 2e-20 71.7 0.0 2.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.11 EIM89447.1 - 1.8e-29 102.6 24.6 1.8e-29 102.6 17.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1449 PF07290.6 EIM89447.1 - 0.025 13.9 0.1 0.073 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF92 PF01940.11 EIM89447.1 - 0.052 12.6 5.2 0.11 11.6 2.5 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF92 WD40 PF00400.27 EIM89449.1 - 1.2e-41 139.0 17.7 2.6e-09 36.5 0.3 6.0 5 1 1 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 EIM89449.1 - 2.2e-05 24.0 0.1 5.5 6.7 0.0 4.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIM89449.1 - 0.014 14.1 0.1 0.026 13.2 0.0 1.6 2 0 0 2 2 2 0 Nup133 N terminal like PQQ_2 PF13360.1 EIM89449.1 - 0.025 14.0 0.2 0.64 9.4 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Gmad1 PF10647.4 EIM89449.1 - 0.16 11.3 4.1 1.1 8.6 2.2 2.3 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 EIM89449.1 - 0.28 10.5 4.9 23 4.4 0.4 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3618 PF12277.3 EIM89451.1 - 0.0038 17.2 0.2 0.0071 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) DUF1510 PF07423.6 EIM89454.1 - 4.6 6.5 17.3 6.6 6.0 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 EIM89454.1 - 5.3 5.1 6.1 6.2 4.9 4.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FA_desaturase PF00487.19 EIM89455.1 - 0.2 11.0 5.7 0.052 12.9 0.3 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Carn_acyltransf PF00755.15 EIM89456.1 - 7.7e-165 549.3 0.0 3e-147 491.2 0.0 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Fe-S_assembly PF04384.8 EIM89458.1 - 0.097 13.0 0.3 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Iron-sulphur cluster assembly Carn_acyltransf PF00755.15 EIM89459.1 - 7.8e-24 83.6 0.1 8.6e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1106 PF06523.6 EIM89462.1 - 0.15 11.8 0.1 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) F-box-like PF12937.2 EIM89462.1 - 0.42 10.3 3.4 0.46 10.2 0.1 2.4 3 0 0 3 3 3 0 F-box-like DUF1793 PF08760.6 EIM89463.1 - 1.7e-09 37.7 0.1 8.7e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) SecY PF00344.15 EIM89464.1 - 8.3e-05 21.6 0.2 9.3e-05 21.5 0.1 1.0 1 0 0 1 1 1 1 SecY translocase SecG PF03840.9 EIM89464.1 - 0.12 12.1 0.8 0.17 11.6 0.6 1.2 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Gly_transf_sug PF04488.10 EIM89467.1 - 3.7e-05 24.0 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIM89467.1 - 0.0019 17.4 0.5 0.003 16.7 0.3 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein LexA_DNA_bind PF01726.11 EIM89467.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Mito_carr PF00153.22 EIM89468.1 - 8.3e-27 92.7 4.7 1.1e-14 53.8 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 EIM89469.1 - 1.4e-14 54.5 9.3 3.1e-14 53.4 6.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM89469.1 - 1.5e-06 28.0 0.0 6.1e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EIM89469.1 - 0.038 13.1 0.1 4 6.4 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase DUF4632 PF15451.1 EIM89469.1 - 0.066 13.1 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Chlorophyllase PF07224.6 EIM89469.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase NicO PF03824.11 EIM89470.1 - 6.1 6.0 13.0 1.2 8.4 1.0 2.8 2 1 1 3 3 3 0 High-affinity nickel-transport protein Glyco_hydro_61 PF03443.9 EIM89471.1 - 6.3e-47 160.2 0.0 7.8e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.23 EIM89472.1 - 4.4e-98 329.3 0.0 5.6e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89472.1 - 7e-06 25.7 2.5 0.0018 17.8 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM89472.1 - 0.043 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Root_cap PF06830.6 EIM89472.1 - 3 7.7 4.9 19 5.1 0.2 3.5 4 0 0 4 4 4 0 Root cap Pro-kuma_activ PF09286.6 EIM89476.1 - 5.4e-38 130.2 0.7 9.1e-38 129.5 0.2 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIM89476.1 - 6.2e-08 32.1 1.9 6.2e-08 32.1 1.3 2.3 2 1 0 2 2 2 1 Subtilase family G-patch_2 PF12656.2 EIM89477.1 - 1.1e-23 82.8 0.1 8.8e-23 79.9 0.0 2.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF336 PF03928.9 EIM89478.1 - 2e-06 27.6 0.3 9e-06 25.5 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF336) adh_short PF00106.20 EIM89480.1 - 4.8e-14 52.6 0.0 7.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89480.1 - 8.4e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89480.1 - 0.00034 20.3 0.0 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 KR domain YjeF_N PF03853.10 EIM89480.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RRM_1 PF00076.17 EIM89482.1 - 1.8e-26 91.5 0.0 1.4e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89482.1 - 9.9e-23 79.9 0.0 8.9e-15 54.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89482.1 - 1.4e-13 50.4 0.0 1.7e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gon7 PF08738.5 EIM89482.1 - 0.34 10.9 3.9 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 Gon7 family YCII PF03795.9 EIM89483.1 - 1.1e-10 41.5 0.1 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Formyl_trans_N PF00551.14 EIM89484.1 - 6.2e-34 117.1 0.0 5.3e-17 61.9 0.1 2.1 2 0 0 2 2 2 2 Formyl transferase AdoHcyase PF05221.12 EIM89485.1 - 0.07 12.0 0.1 0.12 11.3 0.0 1.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase RRM_1 PF00076.17 EIM89486.1 - 3.1e-20 71.5 0.1 2e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89486.1 - 3.3e-17 62.2 0.2 7e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89486.1 - 3.6e-14 52.3 0.1 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM89487.1 - 6.9e-27 92.8 0.0 7.3e-17 60.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89487.1 - 6.7e-22 77.2 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89487.1 - 4.6e-12 45.5 0.0 2.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIM89487.1 - 0.021 14.5 0.3 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_3 PF08777.6 EIM89487.1 - 0.099 12.4 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DUF336 PF03928.9 EIM89490.1 - 1.6e-18 66.7 0.0 7.6e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF336) DUF4137 PF13593.1 EIM89490.1 - 0.037 13.1 0.1 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) FB_lectin PF07367.6 EIM89492.1 - 4.1e-52 175.5 0.2 4.6e-52 175.3 0.2 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin YCII PF03795.9 EIM89493.1 - 1.2e-06 28.6 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF1923 PF09083.5 EIM89493.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Peptidase_A21 PF03566.8 EIM89493.1 - 0.039 12.0 0.0 0.05 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 rve PF00665.21 EIM89496.1 - 0.00033 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 EIM89498.1 - 0.00067 20.1 0.0 0.0017 18.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIM89498.1 - 0.035 14.0 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 EIM89498.1 - 0.63 9.6 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease PrgI PF12666.2 EIM89499.1 - 3.5 7.8 6.9 1.2 9.3 1.9 2.2 1 1 1 2 2 2 0 PrgI family protein Aldo_ket_red PF00248.16 EIM89500.1 - 1.5e-28 99.4 0.0 1.8e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Herpes_gE PF02480.11 EIM89501.1 - 0.0009 17.6 0.2 0.26 9.5 0.0 2.2 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EIM89501.1 - 0.0015 18.2 0.3 0.69 9.5 0.0 2.3 2 0 0 2 2 2 2 Rifin/stevor family EphA2_TM PF14575.1 EIM89501.1 - 0.004 17.5 1.1 0.88 10.0 0.1 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.1 EIM89501.1 - 0.023 14.7 0.3 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) stn_TNFRSF12A PF12191.3 EIM89501.1 - 0.067 13.2 1.3 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Plasmodium_Vir PF05795.6 EIM89501.1 - 0.12 11.5 1.8 6.8 5.7 0.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Amnionless PF14828.1 EIM89501.1 - 0.13 10.7 0.1 7.5 4.9 0.0 2.1 2 0 0 2 2 2 0 Amnionless HLH PF00010.21 EIM89502.1 - 3.4e-12 45.8 0.9 6.7e-12 44.9 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PLA2_B PF01735.13 EIM89503.1 - 5.3e-92 308.5 0.2 1e-91 307.6 0.1 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain F-box-like PF12937.2 EIM89507.1 - 0.00019 21.1 0.2 0.00042 19.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Cauli_VI PF01693.11 EIM89509.1 - 0.092 12.7 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Caulimovirus viroplasmin DUF1846 PF08903.6 EIM89511.1 - 4.2 5.7 0.0 62 1.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) SIR2 PF02146.12 EIM89512.1 - 4.2e-21 75.4 0.0 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Sir2 family SMC_N PF02463.14 EIM89514.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain F-box-like PF12937.2 EIM89517.1 - 6.7e-05 22.5 2.4 0.00017 21.2 1.7 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM89523.1 - 5.7e-06 25.9 0.0 8.5e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89523.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 F-box domain zinc-ribbons_6 PF07191.7 EIM89524.1 - 0.014 15.1 1.1 0.027 14.2 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons RINGv PF12906.2 EIM89524.1 - 0.089 12.8 1.4 0.18 11.8 0.9 1.6 1 0 0 1 1 1 0 RING-variant domain C1_2 PF03107.11 EIM89524.1 - 0.12 12.5 2.3 0.2 11.7 1.6 1.4 1 0 0 1 1 1 0 C1 domain Cript PF10235.4 EIM89524.1 - 0.22 11.9 5.2 0.48 10.8 0.2 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT RecR PF02132.10 EIM89524.1 - 0.3 10.5 2.6 0.56 9.6 1.8 1.4 1 0 0 1 1 1 0 RecR protein ATP-synt_E PF05680.7 EIM89524.1 - 7.1 6.6 10.1 5.8 6.9 5.4 1.8 2 0 0 2 2 2 0 ATP synthase E chain COesterase PF00135.23 EIM89527.1 - 1.6e-77 261.4 0.0 2.5e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89527.1 - 3.6e-09 36.5 0.4 9.7e-09 35.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM89527.1 - 0.0039 16.4 0.3 0.0068 15.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM89527.1 - 0.046 13.4 0.4 0.077 12.7 0.3 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Carboxyl_trans PF01039.17 EIM89529.1 - 3.5e-139 464.3 0.2 4.2e-139 464.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Porin_4 PF13609.1 EIM89530.1 - 0.047 13.2 1.0 0.061 12.8 0.7 1.1 1 0 0 1 1 1 0 Gram-negative porin RabGAP-TBC PF00566.13 EIM89532.1 - 1.4e-38 132.5 0.0 2.5e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.15 EIM89533.1 - 2.5e-18 65.7 0.4 4.4e-18 64.9 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region AAA PF00004.24 EIM89534.1 - 5.2e-16 59.0 0.0 2.5e-15 56.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIM89534.1 - 0.0031 17.2 0.5 0.0097 15.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EIM89534.1 - 0.0056 16.2 0.0 0.007 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM89534.1 - 0.006 17.3 0.0 0.027 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM89534.1 - 0.0068 16.4 0.4 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EIM89534.1 - 0.0083 15.5 0.0 0.026 13.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIM89534.1 - 0.038 13.5 1.4 0.071 12.6 1.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIM89534.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EIM89534.1 - 0.058 13.5 0.2 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EIM89534.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIM89534.1 - 0.084 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FAD_binding_7 PF03441.9 EIM89535.1 - 8.7e-78 261.3 0.0 8.8e-77 258.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIM89535.1 - 9.6e-39 132.7 0.4 1.6e-38 132.0 0.3 1.3 1 0 0 1 1 1 1 DNA photolyase p450 PF00067.17 EIM89536.1 - 2.7e-73 247.0 0.0 3.1e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIM89537.1 - 7e-34 117.0 26.1 8.9e-34 116.7 18.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.1 EIM89537.1 - 0.4 10.0 2.8 1.6 8.1 0.2 2.8 3 0 0 3 3 3 0 Neurensin RPN7 PF10602.4 EIM89538.1 - 2.2e-56 190.0 0.5 3.2e-56 189.5 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIM89538.1 - 1.3e-16 60.8 0.5 3.7e-16 59.3 0.0 2.0 2 1 1 3 3 3 1 PCI domain SAC3_GANP PF03399.11 EIM89538.1 - 0.0016 18.0 0.7 0.0028 17.2 0.5 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EIM89539.1 - 3.9e-18 65.6 0.0 1.3e-17 64.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EIM89539.1 - 0.00018 21.0 0.2 0.41 10.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89539.1 - 0.00046 19.7 0.1 9.1 6.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89539.1 - 0.0014 18.3 0.0 5.6 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89539.1 - 0.0028 18.1 5.1 60 4.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.4 EIM89539.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain NAD_binding_10 PF13460.1 EIM89540.1 - 1e-10 41.9 0.0 0.00073 19.5 0.0 3.0 2 1 0 2 2 2 2 NADH(P)-binding Arginase PF00491.16 EIM89541.1 - 3.9e-80 269.1 0.1 4.9e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EIM89541.1 - 0.019 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Glyco_transf_15 PF01793.11 EIM89542.1 - 1.2e-73 247.9 1.1 1.4e-73 247.7 0.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase LRR_4 PF12799.2 EIM89543.1 - 0.036 13.6 3.4 18 5.0 0.0 4.4 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM89543.1 - 0.14 11.9 6.2 3.5 7.4 0.2 3.8 4 0 0 4 4 4 0 Leucine rich repeat Exo70 PF03081.10 EIM89544.1 - 7.7e-42 143.4 0.0 1.3e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Utp21 PF04192.7 EIM89544.1 - 0.35 9.9 4.9 7.2 5.6 0.2 3.1 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain Ank_2 PF12796.2 EIM89545.1 - 1.7e-15 57.0 0.1 1e-10 41.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DnaJ PF00226.26 EIM89545.1 - 3.1e-14 52.4 2.2 7e-14 51.3 0.2 2.8 2 0 0 2 2 2 1 DnaJ domain Ank_4 PF13637.1 EIM89545.1 - 1.1e-13 51.2 0.0 1.3e-08 35.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM89545.1 - 6.4e-13 47.5 0.0 0.017 15.3 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 EIM89545.1 - 5.7e-12 44.8 0.1 0.018 14.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EIM89545.1 - 1.3e-10 41.1 0.1 4.1e-05 23.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Caldesmon PF02029.10 EIM89545.1 - 4.9e-06 25.2 25.7 4.9e-06 25.2 17.8 4.3 1 1 3 4 4 4 1 Caldesmon DUF4207 PF13904.1 EIM89545.1 - 0.0034 16.8 0.6 0.0034 16.8 0.4 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4207) AIM24 PF01987.12 EIM89546.1 - 1.4e-53 181.5 0.1 1.6e-53 181.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SDA1 PF05285.7 EIM89547.1 - 6.7 5.8 13.1 9 5.4 9.1 1.1 1 0 0 1 1 1 0 SDA1 AP_endonuc_2 PF01261.19 EIM89548.1 - 1.4e-28 99.6 0.0 2.3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel COesterase PF00135.23 EIM89549.1 - 1.9e-91 307.3 1.4 4e-91 306.3 0.9 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89549.1 - 7.5e-08 32.1 0.2 6.9e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89549.1 - 0.0011 18.7 0.1 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM89549.1 - 0.0089 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Response_reg PF00072.19 EIM89550.1 - 3.6e-22 78.4 0.2 9.8e-22 77.0 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 EIM89551.1 - 1.7e-36 124.5 1.2 3.2e-36 123.6 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Snapin_Pallidin PF14712.1 EIM89551.1 - 0.0064 16.7 0.9 0.02 15.1 0.6 1.8 1 1 0 1 1 1 1 Snapin/Pallidin Rab5-bind PF09311.6 EIM89551.1 - 0.025 14.4 1.4 0.042 13.7 0.9 1.3 1 0 0 1 1 1 0 Rabaptin-like protein NAAA-beta PF15508.1 EIM89551.1 - 0.049 13.9 0.4 0.96 9.8 0.0 2.6 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Sybindin PF04099.7 EIM89552.1 - 5.6e-40 136.3 0.0 6.8e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EIM89552.1 - 4.6e-08 33.0 0.0 4.6e-08 33.0 0.0 1.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region COesterase PF00135.23 EIM89554.1 - 2.5e-76 257.5 0.3 3.6e-76 257.0 0.2 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89554.1 - 4.8e-09 36.0 0.5 1.5e-08 34.5 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89554.1 - 5.9e-05 22.8 0.1 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EIM89554.1 - 0.037 12.6 0.0 0.22 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) COesterase PF00135.23 EIM89555.1 - 1.7e-90 304.2 0.4 2.7e-90 303.5 0.3 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89555.1 - 1.7e-09 37.6 1.0 6.7e-09 35.6 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89555.1 - 8.5e-05 22.3 0.3 0.00012 21.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIM89555.1 - 0.02 14.3 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.16 EIM89555.1 - 0.022 13.9 0.1 0.05 12.8 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 EIM89556.1 - 1.5e-92 311.0 1.4 4.3e-92 309.5 0.9 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89556.1 - 1.8e-07 30.9 0.7 1.6e-06 27.8 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89556.1 - 0.00047 19.9 0.1 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM89556.1 - 0.028 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EIM89556.1 - 0.029 13.8 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DUF2424 PF10340.4 EIM89556.1 - 0.11 11.1 0.0 0.6 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) NAD_binding_10 PF13460.1 EIM89557.1 - 4.6e-09 36.5 0.0 0.00099 19.1 0.0 2.9 2 1 0 2 2 2 2 NADH(P)-binding PAP1 PF08601.5 EIM89559.1 - 0.34 10.5 7.2 0.37 10.4 5.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 EIM89559.1 - 2.3 8.2 7.6 2.4 8.1 5.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region APC_CDC26 PF10471.4 EIM89559.1 - 3.4 8.4 6.6 4.5 8.0 4.6 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 LSM14 PF12701.2 EIM89560.1 - 4.8e-28 96.8 0.0 1.2e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EIM89560.1 - 5.1e-07 30.1 16.8 6.9e-07 29.7 9.0 2.5 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EIM89560.1 - 0.0039 17.0 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Ataxin 2 SM domain Nucleoplasmin PF03066.10 EIM89560.1 - 0.36 10.3 4.6 0.55 9.7 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EIM89560.1 - 3.4 8.0 8.0 8.8 6.7 5.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EIM89560.1 - 5.3 4.9 5.9 6.7 4.6 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 EIM89560.1 - 9 5.9 6.6 13 5.3 4.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Clathrin PF00637.15 EIM89561.1 - 5.6e-14 51.9 0.1 3e-09 36.5 0.2 3.1 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EIM89561.1 - 6.7e-08 32.2 0.1 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_16 PF13432.1 EIM89561.1 - 0.031 14.9 4.6 8.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89561.1 - 0.035 13.7 0.2 0.22 11.2 0.0 2.4 3 0 0 3 3 3 0 TPR repeat zf-RING_2 PF13639.1 EIM89561.1 - 0.052 13.3 8.2 0.1 12.4 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 EIM89561.1 - 0.054 13.2 1.8 0.12 12.2 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Apc4_WD40 PF12894.2 EIM89561.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_12 PF13424.1 EIM89561.1 - 0.061 13.2 2.4 0.5 10.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 EIM89561.1 - 0.57 9.9 8.6 1 9.1 5.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM89561.1 - 0.62 10.1 7.9 1.2 9.2 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_J PF04911.7 EIM89562.1 - 1.3e-20 72.6 0.3 1.6e-20 72.3 0.2 1.1 1 0 0 1 1 1 1 ATP synthase j chain Adenylsucc_synt PF00709.16 EIM89564.1 - 5.9e-162 539.1 0.0 6.7e-162 538.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.1 EIM89565.1 - 3.3e-29 100.8 0.2 3.9e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 zf-MYND PF01753.13 EIM89566.1 - 7.9e-10 38.4 10.5 1.9e-09 37.2 7.3 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM89566.1 - 0.028 14.2 13.0 0.074 12.9 6.0 2.7 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 E1_dh PF00676.15 EIM89567.1 - 1.7e-115 384.8 0.0 2e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EIM89567.1 - 0.00011 21.2 0.1 0.00037 19.5 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase HEAT_2 PF13646.1 EIM89568.1 - 4.2e-17 62.2 19.0 2.5e-11 43.6 0.0 7.1 5 3 4 9 9 9 4 HEAT repeats HEAT PF02985.17 EIM89568.1 - 2.3e-16 58.3 20.4 0.015 15.2 0.0 10.6 10 0 0 10 10 10 5 HEAT repeat Arm PF00514.18 EIM89568.1 - 4.8e-16 57.9 22.1 2.5e-06 27.0 0.0 9.1 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EIM89568.1 - 6.6e-08 32.8 28.3 0.0011 19.3 0.3 9.0 8 2 2 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.15 EIM89568.1 - 1.2e-05 23.8 0.1 0.0007 18.0 0.0 3.1 3 0 0 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 EIM89568.1 - 0.0036 17.2 0.1 4.8 7.1 0.0 3.1 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, domain 5 Ric8 PF10165.4 EIM89568.1 - 0.027 13.3 0.0 0.088 11.6 0.0 1.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Cnd1 PF12717.2 EIM89568.1 - 0.19 11.5 0.0 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EIM89568.1 - 0.41 8.8 0.2 4.8 5.3 0.1 2.5 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF605 PF04652.11 EIM89568.1 - 6.9 5.9 12.3 14 4.9 8.5 1.4 1 0 0 1 1 1 0 Vta1 like RdRP PF05183.7 EIM89569.1 - 9.9e-137 457.0 0.0 1.2e-136 456.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase COG6 PF06419.6 EIM89570.1 - 1.8e-135 452.5 0.0 2.5e-135 452.0 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EIM89570.1 - 0.071 12.9 0.2 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Flagellin_C PF00700.16 EIM89570.1 - 0.11 12.6 1.6 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Coa1 PF08695.5 EIM89571.1 - 5.1e-32 109.8 0.2 6.7e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 EIF4E-T PF10477.4 EIM89574.1 - 0.014 14.2 0.7 0.016 14.0 0.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3306 PF11748.3 EIM89575.1 - 0.072 13.7 2.5 12 6.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Peptidase_M28 PF04389.12 EIM89577.1 - 6.3e-35 120.5 0.0 1.1e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 p450 PF00067.17 EIM89578.1 - 3.9e-56 190.5 0.0 3.1e-55 187.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RdRP PF05183.7 EIM89579.1 - 3.6e-149 498.1 0.0 5.5e-149 497.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pkinase_Tyr PF07714.12 EIM89580.1 - 3e-60 203.4 0.0 5.6e-60 202.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.1 EIM89580.1 - 1.3e-56 186.9 43.0 2.5e-09 36.7 0.8 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat Pkinase PF00069.20 EIM89580.1 - 4.8e-51 173.4 0.0 8.9e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.1 EIM89580.1 - 9.4e-50 166.4 33.4 1.8e-12 46.9 1.6 7.8 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89580.1 - 3.8e-09 35.6 13.9 0.02 14.6 0.2 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EIM89580.1 - 1.7e-08 34.4 10.7 0.0013 18.7 0.0 4.3 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIM89580.1 - 2.7e-06 27.8 42.9 0.039 14.6 0.6 7.4 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89580.1 - 4.9e-06 25.9 1.1 2.4 8.1 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89580.1 - 1.7e-05 24.3 13.7 0.24 11.0 0.3 5.5 3 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EIM89580.1 - 2.3e-05 23.9 32.8 0.043 13.7 0.1 9.2 9 0 0 9 9 8 1 Tetratricopeptide repeat PPR PF01535.15 EIM89580.1 - 0.00051 19.8 0.1 13 6.0 0.0 5.9 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.1 EIM89580.1 - 0.0012 19.3 34.1 2.3 9.1 0.0 9.3 6 3 4 10 10 9 2 Tetratricopeptide repeat RIO1 PF01163.17 EIM89580.1 - 0.0022 17.3 0.1 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family TPR_1 PF00515.23 EIM89580.1 - 0.0099 15.4 19.2 0.039 13.5 0.0 7.5 10 0 0 10 10 9 2 Tetratricopeptide repeat DUF2225 PF09986.4 EIM89580.1 - 0.013 14.9 1.9 0.46 9.9 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 EIM89580.1 - 2.2 8.9 16.0 10 6.8 0.1 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Ecl1 PF12855.2 EIM89581.1 - 0.00046 19.4 4.5 0.00087 18.5 3.1 1.3 1 0 0 1 1 1 1 Life-span regulatory factor Metallothio_Pro PF02069.11 EIM89581.1 - 0.073 12.8 1.8 0.16 11.7 1.2 1.5 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-MYND PF01753.13 EIM89581.1 - 0.22 11.4 3.2 0.48 10.3 2.2 1.5 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.4 EIM89581.1 - 0.85 9.4 4.1 1.9 8.3 2.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Vps54 PF07928.7 EIM89583.1 - 2.6e-51 173.3 0.5 5.5e-51 172.2 0.4 1.6 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 EIM89583.1 - 0.031 14.0 0.1 0.076 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) GST_C_3 PF14497.1 EIM89584.1 - 9.2e-06 26.0 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM89584.1 - 0.00042 20.1 0.1 0.00077 19.3 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EIM89586.1 - 2.2e-123 398.2 35.9 1.6e-13 49.9 0.2 10.8 11 0 0 11 11 10 10 WD domain, G-beta repeat eIF2A PF08662.6 EIM89586.1 - 2.4e-15 56.7 0.0 0.001 18.8 0.0 4.2 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 EIM89586.1 - 1.6e-13 50.6 0.0 3.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EIM89586.1 - 1e-11 44.2 14.0 7.8 6.2 0.0 9.2 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EIM89586.1 - 5.6e-07 29.7 0.5 1.9e-06 28.0 0.4 1.9 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 EIM89586.1 - 8e-07 28.7 4.1 0.00011 21.8 0.6 2.9 2 1 1 3 3 3 2 PQQ-like domain DUF285 PF03382.9 EIM89586.1 - 1.2e-05 24.8 0.1 1.6 8.3 0.0 4.7 1 1 2 4 4 4 2 Mycoplasma protein of unknown function, DUF285 Nbas_N PF15492.1 EIM89586.1 - 4.1e-05 22.8 7.5 2.3 7.2 0.1 7.5 1 1 5 7 7 7 1 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIM89586.1 - 0.00023 19.5 0.0 4.4 5.4 0.0 5.0 2 1 5 7 7 7 1 Protein of unknown function (DUF3312) AAA_19 PF13245.1 EIM89586.1 - 0.00044 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RED_C PF07807.6 EIM89586.1 - 0.00049 20.2 0.0 41 4.3 0.0 6.0 1 1 7 8 8 8 0 RED-like protein C-terminal region Peptidase_S9_N PF02897.10 EIM89586.1 - 0.0063 15.1 5.0 6.3 5.2 0.0 5.2 1 1 5 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hira PF07569.6 EIM89586.1 - 0.016 14.4 0.2 53 2.9 0.0 5.3 1 1 7 8 8 8 0 TUP1-like enhancer of split DUF374 PF04028.8 EIM89586.1 - 0.021 14.0 0.2 34 3.7 0.0 5.4 5 1 1 6 6 6 0 Domain of unknown function (DUF374) NB-ARC PF00931.17 EIM89586.1 - 0.044 12.6 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 EIM89586.1 - 0.051 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 EIM89586.1 - 0.052 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2335 PF10097.4 EIM89586.1 - 0.059 13.0 0.0 25 4.5 0.0 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) AAA_22 PF13401.1 EIM89586.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 EIM89587.1 - 3.2e-49 163.5 18.4 4.9e-07 29.4 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EIM89587.1 - 1.1e-44 150.2 7.8 4.4e-14 52.1 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89587.1 - 2e-14 52.2 1.2 0.25 11.3 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89587.1 - 7.5e-13 47.2 3.8 0.07 12.9 0.0 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89587.1 - 6e-12 45.0 7.3 0.5 11.1 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89587.1 - 1.3e-11 44.8 4.5 0.02 15.5 0.0 6.2 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89587.1 - 8.1e-10 38.2 0.0 0.0024 17.4 0.0 5.2 4 1 3 7 7 7 1 TPR repeat TPR_8 PF13181.1 EIM89587.1 - 9.6e-09 34.4 0.0 0.21 11.4 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89587.1 - 1.3e-08 34.0 0.0 0.42 10.3 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM89587.1 - 1.6e-08 34.5 0.1 0.017 15.2 0.0 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIM89587.1 - 3.6e-08 33.3 5.2 18 6.0 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89587.1 - 1.2e-06 28.8 0.6 1.7 9.0 0.0 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIM89587.1 - 0.00038 20.6 13.7 1.2 9.7 0.2 5.5 6 0 0 6 6 4 2 Tetratricopeptide repeat PPR PF01535.15 EIM89587.1 - 0.0063 16.4 0.2 22 5.2 0.0 5.3 7 0 0 7 7 7 0 PPR repeat DUF4416 PF14385.1 EIM89587.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) TRAM_LAG1_CLN8 PF03798.11 EIM89588.1 - 6.2e-31 107.4 14.5 9e-31 106.9 10.0 1.2 1 0 0 1 1 1 1 TLC domain DUF4408 PF14364.1 EIM89589.1 - 0.048 13.2 0.1 0.048 13.2 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4408) Pkinase PF00069.20 EIM89590.1 - 6.9e-52 176.1 0.0 8.3e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89590.1 - 1.2e-30 106.5 0.0 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM89590.1 - 9.4e-06 24.7 0.0 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 EIM89590.1 - 0.0098 14.7 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EIM89590.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIM89590.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family COX7C PF02935.11 EIM89591.1 - 4.8e-05 23.0 0.2 8.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc COX7C PF02935.11 EIM89592.1 - 0.027 14.2 0.1 0.041 13.6 0.1 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc G-gamma PF00631.17 EIM89593.1 - 2.4e-24 84.8 0.0 2.7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain COG5 PF10392.4 EIM89593.1 - 0.042 13.8 0.2 0.047 13.6 0.1 1.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 G-gamma PF00631.17 EIM89594.1 - 1.8e-25 88.4 0.0 2.1e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.15 EIM89595.1 - 1.5e-23 82.4 0.0 1.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIM89595.1 - 1.8e-08 34.5 0.1 2.8e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM89595.1 - 4e-07 30.0 0.0 1.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EIM89595.1 - 0.00046 19.8 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EIM89595.1 - 0.00053 19.9 0.0 0.00094 19.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EIM89595.1 - 0.00055 19.5 0.1 0.0064 16.0 0.0 1.9 1 1 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EIM89595.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin TraF PF13728.1 EIM89595.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.5 1 1 1 2 2 2 0 F plasmid transfer operon protein Cu_bind_like PF02298.12 EIM89596.1 - 0.00088 19.0 0.6 0.0059 16.3 0.4 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 EIM89596.1 - 0.011 15.9 0.5 0.028 14.6 0.1 1.7 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Bul1_C PF04426.7 EIM89598.1 - 0.06 12.5 0.3 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Bul1 C terminus Mem_trans PF03547.13 EIM89600.1 - 1.1e-31 109.5 8.0 1.3e-31 109.2 5.5 1.1 1 0 0 1 1 1 1 Membrane transport protein InaF-motif PF15018.1 EIM89600.1 - 3.6 7.1 9.0 0.31 10.5 2.3 2.3 2 0 0 2 2 2 0 TRP-interacting helix Pkinase_Tyr PF07714.12 EIM89601.1 - 3.1e-40 137.9 0.0 3.5e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM89601.1 - 1e-36 126.4 0.0 1.2e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM89601.1 - 0.013 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EIM89601.1 - 0.17 11.6 0.5 0.29 10.8 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.1 EIM89602.1 - 3.9e-62 206.1 21.6 1.6e-11 43.9 0.1 8.0 5 2 4 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 EIM89602.1 - 2e-59 195.9 31.7 1.4e-06 28.0 0.0 12.7 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89602.1 - 3e-21 73.4 9.5 0.024 14.4 0.0 10.1 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89602.1 - 8e-20 70.9 10.7 2.6e-05 24.4 0.0 7.9 5 3 3 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EIM89602.1 - 4.5e-19 68.3 1.6 0.00039 20.5 0.0 6.5 3 2 5 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIM89602.1 - 3.8e-14 51.9 29.3 1.5 9.6 0.0 11.0 10 2 2 12 12 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89602.1 - 3.8e-14 52.9 27.5 0.00025 21.6 0.0 8.7 3 3 7 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89602.1 - 1.2e-13 49.7 14.7 0.84 9.7 0.0 10.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89602.1 - 5.8e-12 44.6 0.5 7.1 6.4 0.0 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM89602.1 - 6.2e-11 42.0 4.6 1.4 9.4 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89602.1 - 2.3e-10 39.9 5.4 0.95 9.1 0.0 7.1 6 1 1 7 7 7 3 TPR repeat TPR_17 PF13431.1 EIM89602.1 - 1.8e-05 24.5 5.1 1.5e+02 3.0 0.0 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89602.1 - 2.9e-05 23.5 0.0 13 5.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1039 PF06287.6 EIM89602.1 - 0.00077 19.3 0.3 1.8 8.4 0.0 4.6 5 0 0 5 5 5 1 Protein of unknown function (DUF1039) TPR_4 PF07721.9 EIM89602.1 - 0.0011 19.1 39.5 0.98 10.0 0.1 11.0 12 1 0 12 12 12 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIM89602.1 - 0.0019 18.3 20.2 22 5.2 0.0 8.5 2 1 8 10 10 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM89602.1 - 0.0031 17.3 0.3 24 4.9 0.0 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EIM89602.1 - 0.0032 17.2 7.4 20 5.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM89602.1 - 0.69 9.8 21.1 1.2 8.9 0.0 6.8 4 3 4 9 9 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIM89602.1 - 4.2 7.3 14.3 6.1 6.7 0.1 5.1 4 2 3 7 7 6 0 Tetratricopeptide repeat Myotub-related PF06602.9 EIM89604.1 - 4.9e-124 413.6 0.0 6.8e-124 413.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EIM89604.1 - 0.018 15.2 0.1 0.062 13.5 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 EIM89604.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GRAM PF02893.15 EIM89604.1 - 0.053 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Y_phosphatase PF00102.22 EIM89604.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase S-AdoMet_synt_C PF02773.11 EIM89606.1 - 4.1e-77 256.5 0.4 7.4e-77 255.7 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EIM89606.1 - 2.3e-49 166.2 0.0 3.9e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EIM89606.1 - 3.6e-43 145.8 0.9 5.1e-43 145.3 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 EIM89606.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Amidinotransferase ETF_alpha PF00766.14 EIM89606.1 - 0.085 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain S-antigen PF05756.6 EIM89606.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 S-antigen protein GATase_2 PF00310.16 EIM89607.1 - 6.1e-27 94.2 0.0 3.9e-20 71.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIM89607.1 - 1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EIM89607.1 - 5.4e-13 48.7 0.2 9e-13 48.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EIM89607.1 - 1.2e-11 44.3 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIM89607.1 - 6.2e-06 25.0 0.0 1.4e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Synaptonemal_3 PF15191.1 EIM89607.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 DUF3472 PF11958.3 EIM89608.1 - 7.4e-41 140.5 5.5 1.3e-40 139.7 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Glyoxal_oxid_N PF07250.6 EIM89609.1 - 6.2e-50 169.5 0.0 2.6e-49 167.4 0.0 1.9 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIM89609.1 - 3.1e-20 72.0 0.0 1.6e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIM89609.1 - 0.11 12.2 3.3 18 5.2 0.0 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain TPR_10 PF13374.1 EIM89610.1 - 4.5e-91 296.5 63.2 7.5e-09 35.2 0.0 19.4 17 3 2 19 19 19 16 Tetratricopeptide repeat TPR_12 PF13424.1 EIM89610.1 - 3.9e-87 286.2 51.2 2.2e-12 46.7 0.0 11.9 5 2 7 13 13 13 13 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EIM89610.1 - 2.8e-51 174.0 0.0 4.5e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM89610.1 - 3.1e-45 154.3 0.0 6.2e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.1 EIM89610.1 - 3.1e-23 80.1 22.9 0.45 11.2 0.1 15.4 13 2 3 16 16 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89610.1 - 1.1e-22 80.1 7.7 0.00011 22.4 0.1 10.0 4 3 5 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 EIM89610.1 - 1.8e-21 76.0 27.0 0.002 18.2 0.7 8.9 4 2 6 10 10 10 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIM89610.1 - 2.1e-20 72.8 35.8 2.7e-06 27.8 0.1 12.4 10 3 4 14 14 13 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIM89610.1 - 3.5e-20 70.1 13.3 0.0033 17.0 0.1 11.6 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89610.1 - 4.8e-20 69.8 18.7 0.027 14.3 0.1 14.1 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89610.1 - 1.9e-18 65.1 13.2 0.018 14.6 0.1 11.7 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIM89610.1 - 1.2e-13 49.7 7.5 0.057 13.2 0.1 10.7 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM89610.1 - 2.6e-12 46.3 10.8 0.97 10.0 0.0 12.0 15 0 0 15 15 13 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89610.1 - 6.4e-12 44.9 9.4 0.14 11.8 0.0 8.1 8 1 1 9 9 9 6 TPR repeat TPR_4 PF07721.9 EIM89610.1 - 1.6e-09 37.2 5.3 3.5 8.3 0.1 9.7 11 0 0 11 11 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM89610.1 - 0.0055 16.5 10.4 3.6 7.5 0.1 6.5 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EIM89610.1 - 0.0058 16.7 14.8 35 4.9 0.0 10.1 14 0 0 14 14 11 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIM89610.1 - 0.17 11.7 7.9 93 2.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat zf-MYND PF01753.13 EIM89611.1 - 5e-08 32.6 12.9 5e-08 32.6 8.9 1.6 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.2 EIM89612.1 - 5.1e-05 22.9 2.8 5.1e-05 22.9 1.9 2.5 3 0 0 3 3 3 1 F-box-like KH_1 PF00013.24 EIM89613.1 - 0.00016 21.2 2.1 0.00022 20.7 0.7 1.8 2 0 0 2 2 2 1 KH domain DUF3835 PF12927.2 EIM89614.1 - 8.7e-11 42.6 3.2 4.6e-08 33.9 0.4 6.6 6 2 0 6 6 6 3 Domain of unknown function (DUF3835) F-box-like PF12937.2 EIM89615.1 - 6.3e-06 25.8 2.3 6.3e-06 25.8 1.6 2.3 2 0 0 2 2 2 1 F-box-like DUF3808 PF10300.4 EIM89617.1 - 9.3e-77 258.5 0.0 1.8e-76 257.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Apc3 PF12895.2 EIM89617.1 - 2.5e-05 24.3 0.0 7.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIM89617.1 - 0.00013 22.5 1.2 0.012 16.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89617.1 - 0.00018 21.7 0.6 0.00066 19.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89617.1 - 0.00069 19.2 0.3 0.0021 17.6 0.2 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIM89617.1 - 0.016 15.0 2.9 3.2 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIM89617.1 - 0.016 15.0 1.0 11 5.9 0.1 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89617.1 - 0.019 15.5 7.0 11 6.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM89617.1 - 0.93 9.5 5.6 39 4.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Dicty_REP PF05086.7 EIM89617.1 - 6.2 4.4 4.1 8.7 3.9 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1713 PF08213.6 EIM89618.1 - 5.9e-09 35.3 22.3 8.9e-09 34.8 15.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) AAA_19 PF13245.1 EIM89619.1 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EIM89619.1 - 0.0028 17.9 0.3 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM89619.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIM89619.1 - 0.004 17.9 0.1 0.017 15.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EIM89619.1 - 0.0074 15.7 0.1 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EIM89619.1 - 0.0092 16.1 0.1 0.032 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain GvpD PF07088.6 EIM89619.1 - 0.011 14.0 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein T2SE PF00437.15 EIM89619.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EIM89619.1 - 0.025 14.3 0.2 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 NTPase KTI12 PF08433.5 EIM89619.1 - 0.031 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EIM89619.1 - 0.049 13.9 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EIM89619.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EIM89619.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EIM89619.1 - 0.062 12.7 0.9 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EIM89619.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIM89619.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 EIM89619.1 - 0.13 11.5 0.2 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_11 PF13086.1 EIM89619.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM89619.1 - 0.13 12.0 0.3 0.35 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EIM89619.1 - 0.16 11.1 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 EIM89619.1 - 0.17 11.6 0.3 0.76 9.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 KaiC PF06745.8 EIM89619.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 KaiC COX4 PF02936.9 EIM89620.1 - 3.5e-29 101.3 0.0 4.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1726 PF08351.6 EIM89621.1 - 0.037 13.6 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DEC-1_N PF04625.8 EIM89621.1 - 0.34 9.5 3.4 0.3 9.6 2.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF382 PF04037.8 EIM89622.1 - 1.1e-60 203.0 0.8 1.1e-60 203.0 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EIM89622.1 - 7e-19 66.9 6.6 1.3e-18 66.1 4.6 1.5 1 0 0 1 1 1 1 PSP MitMem_reg PF13012.1 EIM89623.1 - 1.1e-37 128.6 0.1 1.8e-37 127.9 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIM89623.1 - 2.4e-27 94.9 0.4 5.8e-27 93.7 0.0 1.8 2 1 1 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pox_Ag35 PF03286.9 EIM89623.1 - 3.5 7.1 11.0 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Arrestin_C PF02752.17 EIM89624.1 - 6.9e-10 39.1 0.1 2.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIM89624.1 - 0.0022 17.7 0.1 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Hamartin PF04388.7 EIM89624.1 - 3 6.3 4.8 5.9 5.4 3.3 1.4 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.2 EIM89625.1 - 3.6e-05 23.4 0.0 0.00011 21.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89625.1 - 0.0038 16.8 0.2 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 F-box domain Protoglobin PF11563.3 EIM89626.1 - 3.2e-36 124.3 0.7 3.6e-36 124.2 0.5 1.0 1 0 0 1 1 1 1 Protoglobin PMT PF02366.13 EIM89627.1 - 1.3e-74 250.6 18.7 1.3e-74 250.6 12.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIM89627.1 - 1.9e-30 105.7 0.2 2.6e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EIM89627.1 - 0.75 9.6 27.9 0.024 14.5 9.5 2.8 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Fibrillarin PF01269.12 EIM89628.1 - 1.1e-108 361.4 0.0 1.4e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIM89628.1 - 0.00046 19.7 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIM89628.1 - 0.00086 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM89628.1 - 0.0013 18.2 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.21 EIM89629.1 - 9.4e-17 60.7 0.5 1.6e-16 60.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM89629.1 - 2.3e-06 28.5 0.1 1.1e-05 26.3 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM89629.1 - 6.2e-06 25.9 0.0 4.6e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_transf_22 PF03901.12 EIM89630.1 - 2.4e-82 277.1 9.1 6.1e-82 275.8 6.3 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 EIM89631.1 - 6.5e-59 199.1 0.0 8.5e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89631.1 - 2.6e-33 115.1 0.0 3.9e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM89631.1 - 7.1e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EIM89631.1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EIM89631.1 - 0.0091 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1635 PF07795.6 EIM89631.1 - 0.012 14.9 0.4 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) YrbL-PhoP_reg PF10707.4 EIM89631.1 - 0.099 11.9 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EIM89632.1 - 4.3e-37 127.6 0.0 6.3e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89632.1 - 5.4e-16 58.4 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM89632.1 - 6.9e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM89632.1 - 0.0017 18.1 0.3 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM89632.1 - 0.035 13.1 0.1 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 EIM89633.1 - 1.1e-31 109.8 27.9 1.6e-31 109.2 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EIM89634.1 - 3.7e-59 194.6 19.6 1.8e-10 40.2 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EIM89634.1 - 1.9e-07 31.0 0.4 0.00093 18.9 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIM89634.1 - 0.004 16.0 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EIM89634.1 - 0.0087 15.5 0.0 5.2 6.6 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EIM89634.1 - 0.013 13.7 0.0 0.12 10.5 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Nbas_N PF15492.1 EIM89634.1 - 0.046 12.8 0.1 9.2 5.2 0.0 3.1 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EIM89634.1 - 0.096 10.4 0.0 0.18 9.5 0.0 1.4 1 1 0 1 1 1 0 IKI3 family Det1 PF09737.4 EIM89634.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Glyco_transf_18 PF15024.1 EIM89635.1 - 6.8e-08 31.3 0.0 1.2e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 18 HSF_DNA-bind PF00447.12 EIM89636.1 - 1.1e-34 118.7 0.4 1.8e-34 118.0 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.17 EIM89636.1 - 0.014 15.5 0.1 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Ets-domain DUF904 PF06005.7 EIM89636.1 - 0.052 13.8 0.6 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Orthopox_A5L PF06193.6 EIM89636.1 - 0.088 12.7 0.4 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like CoaE PF01121.15 EIM89637.1 - 2.8e-62 209.3 0.0 3.6e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EIM89637.1 - 3.1e-06 27.5 0.0 8.9e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM89637.1 - 7.3e-05 23.5 0.1 0.00027 21.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain DSPc PF00782.15 EIM89638.1 - 5.5e-23 81.0 0.0 1.6e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Zip PF02535.17 EIM89638.1 - 0.92 8.4 7.0 1.7 7.6 4.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C3HC4_3 PF13920.1 EIM89639.1 - 2.5e-05 23.8 7.2 2.5e-05 23.8 5.0 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FAA_hydrolase PF01557.13 EIM89640.1 - 1.3e-56 191.4 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 EIM89640.1 - 0.052 13.1 0.5 0.52 9.9 0.1 2.5 2 0 0 2 2 2 0 KH domain Aminotran_1_2 PF00155.16 EIM89641.1 - 0.00082 18.4 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_13 PF13166.1 EIM89641.1 - 0.0021 16.5 0.1 0.0027 16.2 0.1 1.0 1 0 0 1 1 1 1 AAA domain Snapin_Pallidin PF14712.1 EIM89641.1 - 0.0037 17.5 4.1 0.59 10.4 0.1 2.5 2 1 1 3 3 2 2 Snapin/Pallidin Laminin_II PF06009.7 EIM89641.1 - 0.0075 16.0 1.4 0.17 11.6 0.2 2.4 2 1 0 2 2 2 1 Laminin Domain II DUF4140 PF13600.1 EIM89641.1 - 0.015 15.7 4.9 1.8 9.0 0.2 3.0 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tektin PF03148.9 EIM89641.1 - 0.018 13.5 0.9 0.44 9.0 0.1 2.2 2 0 0 2 2 2 0 Tektin family DUF1664 PF07889.7 EIM89641.1 - 0.018 14.8 1.5 5.9 6.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 EIM89641.1 - 0.029 14.1 1.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 EIM89641.1 - 0.03 14.2 1.8 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EIM89641.1 - 0.04 13.6 2.2 0.97 9.1 0.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HSBP1 PF06825.7 EIM89641.1 - 0.085 12.4 0.5 8.4 6.0 0.0 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 NPV_P10 PF05531.7 EIM89641.1 - 0.087 13.0 0.1 15 5.9 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 EIM89641.1 - 0.098 12.3 0.6 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Baculo_PEP_C PF04513.7 EIM89641.1 - 0.1 12.4 1.0 0.37 10.5 0.2 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EIM89641.1 - 0.12 12.2 3.6 5.3 6.9 0.0 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ALIX_LYPXL_bnd PF13949.1 EIM89641.1 - 0.24 10.3 4.5 1.1 8.2 3.1 1.8 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV MscS_porin PF12795.2 EIM89641.1 - 0.28 10.4 6.5 2.2 7.5 0.4 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EIM89641.1 - 0.31 10.1 3.5 1.3 8.1 2.4 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COG2 PF06148.6 EIM89641.1 - 0.32 10.8 4.3 1.1 9.1 0.9 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.7 EIM89641.1 - 0.4 10.7 3.9 18 5.4 0.1 3.4 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF2360 PF10152.4 EIM89641.1 - 0.66 10.2 7.8 0.048 13.9 2.0 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Tmemb_cc2 PF10267.4 EIM89641.1 - 1.6 7.1 6.5 0.41 9.1 1.1 1.9 1 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein LytR_cpsA_psr PF03816.9 EIM89643.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain APC_CDC26 PF10471.4 EIM89644.1 - 0.005 17.5 1.2 0.005 17.5 0.8 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 DUF1645 PF07816.6 EIM89644.1 - 0.043 14.2 7.2 0.049 14.1 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF1777 PF08648.7 EIM89644.1 - 0.094 12.4 7.2 0.12 12.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RR_TM4-6 PF06459.7 EIM89644.1 - 0.19 11.5 6.0 0.21 11.4 4.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DOR PF14839.1 EIM89644.1 - 0.64 9.7 6.0 0.78 9.4 4.2 1.1 1 0 0 1 1 1 0 DOR family NARP1 PF12569.3 EIM89644.1 - 0.67 8.6 9.1 0.72 8.5 6.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4407 PF14362.1 EIM89644.1 - 0.92 8.4 5.1 1.1 8.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CMS1 PF14617.1 EIM89644.1 - 1.1 8.2 7.1 1.5 7.8 4.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Adeno_PIX PF03955.9 EIM89644.1 - 1.6 9.2 5.1 0.82 10.2 1.0 1.8 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) PAP_assoc PF03828.14 EIM89645.1 - 7e-17 61.1 0.0 1.7e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIM89645.1 - 2.7e-08 34.0 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Band_7_1 PF13421.1 EIM89645.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Opacity PF02462.10 EIM89647.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Opacity family porin protein NfeD PF01957.13 EIM89647.1 - 0.26 11.4 5.7 0.23 11.5 0.2 3.3 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding zf-CCHC PF00098.18 EIM89648.1 - 3.7e-06 26.5 0.7 5.3e-06 26.1 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIM89648.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle ATP-synt_Eps PF04627.8 EIM89649.1 - 2.1e-20 72.0 0.9 2.7e-20 71.6 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.17 EIM89650.1 - 4.9e-51 172.3 0.0 6e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89650.1 - 1.5e-14 54.4 0.0 2.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM89650.1 - 7e-11 41.6 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM89650.1 - 0.00024 20.5 0.0 0.0058 16.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM89650.1 - 0.0016 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ORC6 PF05460.8 EIM89650.1 - 0.013 14.6 4.8 0.016 14.3 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAP1 PF08601.5 EIM89650.1 - 0.059 13.0 5.3 0.075 12.7 3.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Med13_C PF06333.7 EIM89650.1 - 0.075 11.5 2.0 0.095 11.2 1.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal CAF-1_p150 PF11600.3 EIM89650.1 - 0.22 10.8 5.5 0.3 10.4 3.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DEAD PF00270.24 EIM89651.1 - 4.2e-43 146.7 2.6 1.2e-42 145.2 0.5 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM89651.1 - 8.1e-27 92.9 0.2 2.7e-26 91.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIM89651.1 - 0.00071 19.2 0.4 0.0023 17.6 0.1 2.0 1 1 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EIM89651.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIM89651.1 - 0.0069 15.9 0.4 0.02 14.4 0.2 1.9 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EIM89651.1 - 0.011 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EIM89651.1 - 0.011 15.9 0.1 0.04 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EIM89651.1 - 0.08 12.6 0.2 0.39 10.4 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain F-box-like PF12937.2 EIM89652.1 - 1.1e-07 31.4 2.7 1.1e-07 31.4 1.8 3.1 3 1 0 3 3 3 1 F-box-like Asp_protease_2 PF13650.1 EIM89653.1 - 9.8e-08 32.3 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIM89653.1 - 0.0011 18.6 0.1 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1863 PF08937.6 EIM89654.1 - 0.058 13.4 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) UCH PF00443.24 EIM89658.1 - 2.3e-47 161.3 0.0 4.3e-47 160.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM89658.1 - 2.3e-13 50.2 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Spc7 PF08317.6 EIM89659.1 - 5.4 5.5 21.6 1.2 7.6 4.1 3.4 1 1 1 3 3 3 0 Spc7 kinetochore protein Epimerase PF01370.16 EIM89660.1 - 9.4e-16 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM89660.1 - 2.2e-12 46.2 0.0 3.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM89660.1 - 1.4e-08 34.9 0.0 5.3e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM89660.1 - 8.7e-08 31.3 0.0 8.2e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EIM89660.1 - 0.00098 19.0 0.2 0.0061 16.4 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM89660.1 - 0.0038 16.5 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EIM89660.1 - 0.41 10.2 2.5 5.4 6.6 1.7 2.1 1 1 0 1 1 1 0 KR domain Choline_transpo PF04515.7 EIM89661.1 - 2.8e-14 52.6 15.9 1.1e-11 44.1 6.4 3.4 2 1 0 2 2 2 2 Plasma-membrane choline transporter SAPS PF04499.10 EIM89662.1 - 1.4e-126 422.9 0.0 1.9e-126 422.5 0.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein BUD22 PF09073.5 EIM89662.1 - 5 6.0 19.1 0.062 12.3 0.3 2.4 2 0 0 2 2 2 0 BUD22 Adap_comp_sub PF00928.16 EIM89663.1 - 8.1e-84 280.7 0.5 1.1e-83 280.3 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIM89663.1 - 9.9e-06 25.3 0.9 1.8e-05 24.4 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Epimerase PF01370.16 EIM89665.1 - 4.7e-08 32.7 0.0 1.5e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM89665.1 - 1.2e-07 30.7 0.0 1.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM89665.1 - 2.8e-05 23.1 0.0 4.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIM89665.1 - 0.00067 19.7 0.0 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding ATP_bind_3 PF01171.15 EIM89666.1 - 2.9e-36 124.6 0.0 4.5e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family CENP-C_C PF11699.3 EIM89667.1 - 1.2e-26 92.4 0.1 1.9e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EIM89667.1 - 1.2e-06 27.9 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIM89667.1 - 0.039 13.6 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain APH PF01636.18 EIM89670.1 - 0.013 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Terpene_synth_C PF03936.11 EIM89671.1 - 7e-18 64.8 0.0 8.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3429 PF11911.3 EIM89672.1 - 1.1e-35 122.6 13.4 1.5e-35 122.2 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Aha1_N PF09229.6 EIM89673.1 - 1.3e-23 83.2 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EIM89673.1 - 1.4e-12 47.8 1.0 2.2e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein PARP PF00644.15 EIM89674.1 - 3.2e-09 36.5 4.3 2e-07 30.6 0.7 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Perm-CXXC PF15629.1 EIM89674.1 - 0.42 10.6 5.9 0.61 10.1 4.1 1.2 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DUF2321 PF10083.4 EIM89675.1 - 0.13 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) F-box-like PF12937.2 EIM89676.1 - 2.9e-07 30.1 0.0 8.4e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like Mto2_bdg PF12808.2 EIM89676.1 - 0.0011 19.0 0.7 0.0022 18.0 0.5 1.5 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Shugoshin_N PF07558.6 EIM89676.1 - 0.029 14.0 0.1 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Prefoldin_2 PF01920.15 EIM89676.1 - 0.19 11.4 0.1 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Glyco_hydro_3 PF00933.16 EIM89677.1 - 1.6e-62 211.1 0.0 2.3e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM89677.1 - 6.4e-46 156.7 0.0 9.4e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM89677.1 - 8e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain E1-E2_ATPase PF00122.15 EIM89678.1 - 9.9e-17 60.7 0.0 2.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIM89678.1 - 1.8e-13 51.3 1.8 2.3e-05 24.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM89678.1 - 2.5e-13 50.6 0.2 8.6e-13 48.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM89678.1 - 1.2e-07 31.5 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIM89678.1 - 0.00017 21.2 0.6 0.0041 16.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EIM89679.1 - 1.3e-10 40.7 1.3 1.3e-10 40.7 0.9 2.6 3 0 0 3 3 3 1 F-box-like DUF4470 PF14737.1 EIM89681.1 - 8.4e-10 38.2 0.0 2.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EIM89681.1 - 0.071 12.7 1.2 0.16 11.6 0.8 1.5 1 0 0 1 1 1 0 TPR repeat DUF2786 PF10979.3 EIM89682.1 - 1.5e-09 37.4 5.6 1.5e-09 37.4 3.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) HNF-1_N PF04814.8 EIM89682.1 - 7.5 6.6 12.5 1.6 8.7 0.0 3.4 3 2 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pam17 PF08566.5 EIM89683.1 - 2.4e-53 180.4 0.0 1.2e-42 145.4 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial import protein Pam17 SNF2_N PF00176.18 EIM89684.1 - 9.1e-37 126.4 0.0 5.8e-30 104.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM89684.1 - 0.00072 19.3 0.6 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GPI-anchored PF10342.4 EIM89685.1 - 1.1e-05 25.7 0.1 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIM89685.1 - 0.039 13.4 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RHSP PF07999.6 EIM89686.1 - 0.00038 19.1 0.0 0.029 12.9 0.0 2.2 2 0 0 2 2 2 2 Retrotransposon hot spot protein T2SE PF00437.15 EIM89686.1 - 0.06 12.2 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EIM89686.1 - 0.18 11.5 0.1 0.67 9.7 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain WD40 PF00400.27 EIM89687.1 - 4.7e-40 134.0 14.1 3.5e-07 29.8 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIM89687.1 - 3.6e-13 48.9 1.9 8.1e-13 47.8 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89687.1 - 3.1e-08 33.0 1.6 7.6e-08 31.8 1.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIM89687.1 - 3.8e-05 22.0 0.0 0.088 10.9 0.0 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 SH3_9 PF14604.1 EIM89688.1 - 1.1e-07 31.2 0.0 1.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM89688.1 - 8.5e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIM89688.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L32p PF01783.18 EIM89689.1 - 0.11 12.6 0.5 0.46 10.6 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family DUF4470 PF14737.1 EIM89690.1 - 2.5e-09 36.7 0.0 6.1e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EIM89690.1 - 1.1e-07 31.3 0.0 2.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIM89690.1 - 0.00075 19.2 0.1 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM89690.1 - 0.032 14.5 0.7 0.12 12.6 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89690.1 - 0.097 13.3 3.4 0.14 12.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat YjbE PF11106.3 EIM89691.1 - 8.7 6.3 22.1 0.2 11.6 10.8 1.7 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE F-box-like PF12937.2 EIM89692.1 - 1.2e-09 37.7 1.9 2e-09 37.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EIM89692.1 - 0.41 10.8 1.9 47 4.4 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat AAA_5 PF07728.9 EIM89693.1 - 7.6e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM89693.1 - 4e-09 36.6 0.0 9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIM89693.1 - 1.6e-06 28.3 0.0 4.1e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM89693.1 - 6.6e-06 26.2 0.0 2.5e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM89693.1 - 7.8e-05 22.7 0.0 0.0075 16.2 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Ank_2 PF12796.2 EIM89693.1 - 0.00052 20.3 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_14 PF13173.1 EIM89693.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIM89693.1 - 0.0029 17.7 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EIM89693.1 - 0.0047 16.8 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM89693.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EIM89693.1 - 0.0067 15.6 0.0 0.027 13.6 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 EIM89693.1 - 0.011 14.4 0.0 0.032 12.9 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain RuvB_N PF05496.7 EIM89693.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Ank_3 PF13606.1 EIM89693.1 - 0.027 14.6 0.0 3.5 8.1 0.0 2.8 3 0 0 3 3 2 0 Ankyrin repeat AAA_17 PF13207.1 EIM89693.1 - 0.029 15.1 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 EIM89693.1 - 0.03 14.1 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Sigma54_activat PF00158.21 EIM89693.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIM89693.1 - 0.078 12.6 0.0 9.6 5.8 0.0 2.6 2 1 0 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 EIM89693.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein F-box-like PF12937.2 EIM89694.1 - 1.9e-06 27.5 2.0 7.7e-06 25.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.13 EIM89695.1 - 8.9e-10 38.2 20.0 1.6e-09 37.4 13.9 1.5 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.1 EIM89695.1 - 0.041 14.2 3.8 15 6.0 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM89695.1 - 0.081 13.6 5.6 9.9 7.1 0.4 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89695.1 - 0.13 11.9 6.7 1.4 8.5 0.1 3.1 3 0 0 3 3 3 0 TPR repeat Dak1 PF02733.12 EIM89699.1 - 4.8e-80 268.5 1.8 6.6e-79 264.8 1.2 2.0 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIM89699.1 - 1.1e-37 129.3 0.2 2.2e-37 128.4 0.1 1.5 1 0 0 1 1 1 1 DAK2 domain Pkinase PF00069.20 EIM89700.1 - 0.0042 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM89700.1 - 0.053 13.2 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Epimerase PF01370.16 EIM89701.1 - 0.01 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family COX15-CtaA PF02628.10 EIM89702.1 - 0.0064 15.3 1.1 0.0064 15.3 0.8 1.4 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein MpPF26 PF07666.6 EIM89702.1 - 0.075 12.9 0.4 0.075 12.9 0.2 1.4 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2975 PF11188.3 EIM89702.1 - 0.096 12.3 5.1 1 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) tRNA_Me_trans PF03054.11 EIM89703.1 - 9.7e-121 402.6 0.0 1.1e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EIM89703.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 EIM89703.1 - 0.026 13.4 0.0 1.3 7.8 0.0 2.5 2 1 0 2 2 2 0 NAD synthase ATP_bind_3 PF01171.15 EIM89703.1 - 0.049 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 PP-loop family TPP_enzyme_N PF02776.13 EIM89704.1 - 8.2e-57 191.4 0.1 1e-55 187.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EIM89704.1 - 7.6e-49 165.2 0.3 3.7e-47 159.7 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIM89704.1 - 1e-35 122.4 1.3 2.3e-35 121.3 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ank_4 PF13637.1 EIM89705.1 - 2.8e-08 34.0 1.0 0.00044 20.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM89705.1 - 1.5e-06 28.4 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM89705.1 - 1.6e-05 24.4 0.0 5.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EIM89705.1 - 0.041 14.1 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat PCMT PF01135.14 EIM89705.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_pol_phi PF04931.8 EIM89705.1 - 2.1 6.0 8.2 3 5.5 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-MYND PF01753.13 EIM89708.1 - 2.1e-09 37.0 12.5 4.3e-09 36.0 8.6 1.5 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.1 EIM89708.1 - 1.3e-06 28.4 3.2 0.15 12.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89708.1 - 3e-05 24.5 1.0 0.61 10.8 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM89708.1 - 0.00014 21.5 0.3 3.3 7.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM89708.1 - 0.0082 15.7 1.8 4.3 7.0 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EIM89708.1 - 0.0091 16.3 4.0 2.1 8.7 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM89708.1 - 0.019 14.8 4.0 5.7 6.9 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM89708.1 - 0.025 14.4 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM89708.1 - 0.032 13.8 0.1 28 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM89708.1 - 0.071 13.0 1.2 12 5.9 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat GTP1_OBG PF01018.17 EIM89709.1 - 1.3e-35 122.3 1.9 4.6e-26 91.3 0.5 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EIM89709.1 - 3.1e-17 62.5 0.0 7.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EIM89709.1 - 1.4e-05 24.0 1.7 0.024 13.4 0.1 2.2 2 0 0 2 2 2 2 ArgK protein cobW PF02492.14 EIM89709.1 - 0.00013 21.4 0.1 0.0026 17.2 0.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EIM89709.1 - 0.00032 19.9 0.0 0.00071 18.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIM89709.1 - 0.00062 19.6 0.0 0.0022 17.8 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 EIM89709.1 - 0.00094 19.6 0.0 0.64 10.5 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EIM89709.1 - 0.001 18.5 0.1 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIM89709.1 - 0.0033 17.7 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Arf PF00025.16 EIM89709.1 - 0.0056 15.9 0.2 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MobB PF03205.9 EIM89709.1 - 0.021 14.5 0.1 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM89709.1 - 0.053 14.3 0.1 0.3 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIM89709.1 - 0.083 13.1 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain RRM_3 PF08777.6 EIM89710.1 - 0.00012 21.8 0.0 0.0014 18.4 0.0 2.3 1 1 1 2 2 2 1 RNA binding motif RRM_6 PF14259.1 EIM89710.1 - 0.00065 19.6 0.0 0.17 11.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM89710.1 - 0.0075 15.8 0.1 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C12 PF01088.16 EIM89711.1 - 3.3e-58 196.3 0.0 3.8e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Tim54 PF11711.3 EIM89712.1 - 1.5e-71 241.0 0.0 2.3e-71 240.4 0.0 1.3 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.11 EIM89713.1 - 2.7e-39 135.2 0.0 4.5e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIM89713.1 - 3.3e-23 82.0 0.0 9.8e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM89713.1 - 1.1e-07 31.5 0.1 3.2e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM89713.1 - 2.2e-07 30.9 0.0 6.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM89713.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain HHH_5 PF14520.1 EIM89713.1 - 0.039 14.1 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain CKS PF01111.14 EIM89714.1 - 4.9e-36 122.3 0.3 6.9e-36 121.9 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.2 EIM89714.1 - 0.0019 17.4 0.3 0.002 17.3 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3822) Cerato-platanin PF07249.7 EIM89715.1 - 1.9e-42 144.0 1.6 2.3e-42 143.7 1.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EIM89715.1 - 0.0025 17.4 0.4 0.0041 16.7 0.3 1.3 1 1 0 1 1 1 1 Barwin family Asp PF00026.18 EIM89716.1 - 1.3e-79 267.7 11.3 1.5e-79 267.5 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM89716.1 - 1.9e-05 24.6 4.6 1.9e-05 24.6 3.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM89716.1 - 0.0067 15.9 0.2 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 EIM89717.1 - 1.1e-81 274.5 14.5 1.3e-81 274.2 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM89717.1 - 1e-05 25.5 5.6 4.2e-05 23.5 3.9 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIM89717.1 - 0.00081 18.9 0.1 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal NUDIX PF00293.23 EIM89718.1 - 6.5e-15 54.9 0.0 4.1e-13 49.1 0.0 2.8 2 1 0 2 2 2 2 NUDIX domain Glyco_hydro_18 PF00704.23 EIM89719.1 - 6.4e-19 68.6 0.7 8.6e-18 64.8 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_35 PF01301.14 EIM89720.1 - 1.2e-76 258.0 1.4 1.7e-76 257.6 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM89720.1 - 3.1e-44 149.7 8.8 4.3e-22 78.4 0.1 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM89720.1 - 2.6e-36 124.7 4.5 4.7e-36 123.8 3.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM89720.1 - 2.2e-18 65.3 0.4 2.3e-17 62.1 0.1 2.6 1 1 1 2 2 2 1 Beta-galactosidase, domain 3 Rho_RNA_bind PF07497.7 EIM89720.1 - 0.015 14.9 0.1 0.053 13.1 0.1 1.9 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain PerB PF06590.6 EIM89720.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 PerB protein AF1Q PF15017.1 EIM89720.1 - 0.18 11.7 0.1 0.54 10.2 0.1 1.7 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Herpes_UL45 PF05473.7 EIM89722.1 - 0.0069 15.8 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 UL45 protein MARVEL PF01284.18 EIM89722.1 - 0.033 14.0 15.9 0.06 13.1 10.1 2.4 1 1 0 1 1 1 0 Membrane-associating domain Peptidase_M16 PF00675.15 EIM89723.1 - 2.4e-37 127.9 0.5 3.1e-36 124.3 0.1 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIM89723.1 - 1.8e-22 79.9 0.0 2.2e-10 40.4 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain bZIP_1 PF00170.16 EIM89724.1 - 0.23 11.4 4.7 0.11 12.4 0.9 2.1 2 0 0 2 2 2 0 bZIP transcription factor SKIP_SNW PF02731.10 EIM89725.1 - 1.2e-66 223.0 1.4 1.2e-66 223.0 1.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain ALAD PF00490.16 EIM89726.1 - 7e-118 393.2 0.0 8.5e-118 392.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MRJP PF03022.11 EIM89727.1 - 8.3e-29 100.6 0.0 2.8e-28 98.9 0.0 1.7 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EIM89727.1 - 0.00013 21.4 0.0 0.00056 19.3 0.0 2.0 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EIM89727.1 - 0.072 13.0 0.5 50 4.1 0.0 4.4 5 0 0 5 5 5 0 NHL repeat Septin PF00735.13 EIM89729.1 - 4.2e-115 383.6 0.7 4.9e-115 383.3 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIM89729.1 - 7.1e-08 32.4 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIM89729.1 - 1.4e-06 27.6 0.0 2.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EIM89729.1 - 3.3e-06 26.3 0.0 5.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIM89729.1 - 2.8e-05 24.0 0.6 0.071 12.9 0.1 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EIM89729.1 - 6.1e-05 22.5 0.3 0.00093 18.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIM89729.1 - 9.2e-05 22.7 0.1 0.00043 20.5 0.1 2.0 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 EIM89729.1 - 0.00026 20.5 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EIM89729.1 - 0.0011 18.1 0.3 0.003 16.7 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 EIM89729.1 - 0.0011 18.4 0.3 0.0025 17.3 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EIM89729.1 - 0.0015 17.5 0.1 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 EIM89729.1 - 0.0027 16.5 0.1 0.0064 15.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 EIM89729.1 - 0.0055 17.1 0.1 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EIM89729.1 - 0.015 14.1 0.1 0.08 11.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EIM89729.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EIM89729.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM89729.1 - 0.028 14.5 0.0 0.093 12.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain Ras PF00071.17 EIM89729.1 - 0.035 13.5 0.3 0.46 9.8 0.0 2.6 2 2 0 2 2 2 0 Ras family MobB PF03205.9 EIM89729.1 - 0.048 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EIM89729.1 - 0.055 13.3 0.1 0.24 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIM89729.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIM89729.1 - 0.093 13.0 0.2 0.15 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIM89729.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain EHN PF06441.7 EIM89732.1 - 4.2e-33 113.6 0.3 9.8e-32 109.2 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIM89732.1 - 3.3e-11 43.5 1.5 3.3e-11 43.5 1.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89732.1 - 2.2e-06 27.3 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold VRR_NUC PF08774.6 EIM89733.1 - 5.8e-19 67.9 0.1 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain F-box-like PF12937.2 EIM89735.1 - 6.2e-08 32.2 1.0 6.2e-08 32.2 0.7 2.6 2 1 0 2 2 2 1 F-box-like Cyclin PF08613.6 EIM89736.1 - 3.2e-11 43.8 1.1 4.3e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIM89736.1 - 1.6e-09 37.3 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C4H2 PF10146.4 EIM89737.1 - 6.1e-06 26.4 1.9 7.4e-06 26.1 1.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Vps5 PF09325.5 EIM89737.1 - 0.0022 17.3 4.1 0.0022 17.3 2.8 1.4 1 1 0 1 1 1 1 Vps5 C terminal like Latarcin PF10279.4 EIM89737.1 - 0.03 14.5 1.7 0.03 14.5 1.2 1.6 2 0 0 2 2 1 0 Latarcin precursor DUF4047 PF13256.1 EIM89737.1 - 0.077 12.9 3.3 0.038 13.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) HemY_N PF07219.8 EIM89737.1 - 0.14 11.6 1.0 3.6 7.1 0.0 2.6 2 1 1 3 3 3 0 HemY protein N-terminus TBPIP PF07106.8 EIM89737.1 - 0.18 11.3 8.4 0.086 12.3 4.1 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ERM PF00769.14 EIM89737.1 - 0.2 11.1 12.2 0.3 10.5 8.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Snapin_Pallidin PF14712.1 EIM89737.1 - 0.22 11.8 6.3 0.18 12.1 3.3 1.7 1 1 0 1 1 1 0 Snapin/Pallidin IncA PF04156.9 EIM89737.1 - 0.32 10.5 19.4 0.73 9.3 13.4 1.6 1 1 0 1 1 1 0 IncA protein TMCO5 PF14992.1 EIM89737.1 - 0.53 9.3 9.4 1 8.4 6.4 1.5 1 1 0 1 1 1 0 TMCO5 family APG6 PF04111.7 EIM89737.1 - 0.65 8.9 12.2 0.19 10.7 6.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S46 PF10459.4 EIM89737.1 - 0.78 8.0 6.9 0.9 7.8 4.8 1.0 1 0 0 1 1 1 0 Peptidase S46 COG2 PF06148.6 EIM89737.1 - 0.88 9.4 6.0 0.81 9.5 2.6 1.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.6 EIM89737.1 - 0.99 7.8 11.9 1.7 7.0 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 EIM89737.1 - 1.3 6.8 5.1 1.5 6.5 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_Gp23 PF10669.4 EIM89737.1 - 1.3 9.1 4.7 2.9 8.0 3.1 1.7 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DivIC PF04977.10 EIM89737.1 - 2 7.9 13.3 0.22 11.0 3.1 2.8 2 1 1 3 3 3 0 Septum formation initiator EcoEI_R_C PF08463.5 EIM89737.1 - 2.7 7.8 10.0 6.5 6.5 6.9 1.5 1 1 0 1 1 1 0 EcoEI R protein C-terminal Lge1 PF11488.3 EIM89737.1 - 3.6 7.8 6.5 1.3 9.2 1.8 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF972 PF06156.8 EIM89737.1 - 6.1 7.2 9.6 4.3 7.7 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 EIM89737.1 - 6.8 6.3 10.2 4 7.0 2.2 2.6 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) His_Phos_2 PF00328.17 EIM89738.1 - 2.1e-21 76.6 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2404 PF10296.4 EIM89739.1 - 0.012 15.6 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Minor_tail_Z PF06763.6 EIM89739.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) FliJ PF02050.11 EIM89740.1 - 0.00046 20.2 10.3 0.00046 20.2 7.1 2.5 3 1 0 3 3 3 1 Flagellar FliJ protein Exonuc_VII_L PF02601.10 EIM89740.1 - 0.012 14.8 1.0 0.019 14.1 0.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 EIM89740.1 - 0.47 9.3 7.2 0.87 8.4 4.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BRE1 PF08647.6 EIM89740.1 - 0.75 9.8 4.9 0.27 11.2 0.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 EIM89740.1 - 0.87 9.4 10.7 0.59 10.0 2.6 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EIM89740.1 - 1.6 8.4 10.9 0.31 10.8 4.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.4 EIM89740.1 - 4.1 6.0 7.4 1.9 7.1 2.5 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3608 PF12257.3 EIM89743.1 - 1.3e-63 214.5 0.0 6.1e-63 212.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EIM89743.1 - 4.6e-19 67.9 0.1 9.2e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Antitoxin-MazE PF04014.13 EIM89743.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Acetyltransf_1 PF00583.19 EIM89744.1 - 2e-10 40.5 0.1 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM89744.1 - 5e-05 23.3 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM89744.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIM89744.1 - 0.02 14.7 0.3 0.037 13.8 0.2 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM89744.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.2 EIM89745.1 - 9.2e-10 38.0 2.0 1.9e-09 37.0 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89745.1 - 0.018 14.6 0.4 4 7.1 0.0 2.7 2 0 0 2 2 2 0 F-box domain An_peroxidase PF03098.10 EIM89745.1 - 0.028 12.8 0.3 0.063 11.6 0.0 1.7 2 0 0 2 2 2 0 Animal haem peroxidase NTP_transferase PF00483.18 EIM89746.1 - 1.3e-39 136.0 0.0 2.3e-39 135.1 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIM89746.1 - 5.7e-06 26.4 0.1 1.3e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EIM89746.1 - 5.8e-05 22.7 0.1 9.4e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Radical_SAM PF04055.16 EIM89747.1 - 2.2e-16 60.4 0.1 7.8e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EIM89747.1 - 1.8e-11 43.9 0.0 5.3e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM89747.1 - 0.0084 16.2 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM89747.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein GDA1_CD39 PF01150.12 EIM89748.1 - 5.2e-105 351.4 0.0 4.6e-97 325.2 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EIM89748.1 - 0.026 13.7 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family PWWP PF00855.12 EIM89749.1 - 0.021 15.0 0.1 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 PWWP domain Fungal_trans PF04082.13 EIM89751.1 - 8.4e-19 67.4 0.1 1.8e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM89751.1 - 1.7e-05 24.5 8.4 3.2e-05 23.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.17 EIM89752.1 - 8.6e-09 34.9 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EIM89752.1 - 4.7e-06 26.0 0.4 2.6e-05 23.6 0.2 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EIM89752.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 0 Cupin AraC_binding PF02311.14 EIM89752.1 - 0.023 14.3 0.1 0.04 13.5 0.1 1.4 1 1 0 1 1 1 0 AraC-like ligand binding domain PhyH PF05721.8 EIM89752.1 - 0.033 14.2 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) GPI PF06560.6 EIM89752.1 - 0.06 12.3 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) 2OG-FeII_Oxy_5 PF13759.1 EIM89752.1 - 0.061 13.6 0.6 0.21 11.9 0.4 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ARD PF03079.9 EIM89752.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family WD40 PF00400.27 EIM89753.1 - 2.6e-55 182.4 24.0 4.3e-10 39.0 0.3 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIM89753.1 - 6.1e-11 41.8 0.6 1.3e-10 40.8 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89753.1 - 1.2e-09 37.6 0.2 1.2e-09 37.6 0.1 2.6 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.3 EIM89753.1 - 2.2e-05 22.8 13.2 0.1 10.6 0.1 5.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIM89753.1 - 0.00062 18.6 2.1 2.6 6.6 0.0 3.9 3 1 1 4 4 4 2 Nup133 N terminal like Daxx PF03344.10 EIM89753.1 - 0.16 10.4 4.1 0.22 9.9 2.9 1.1 1 0 0 1 1 1 0 Daxx Family zf-C3HC4_3 PF13920.1 EIM89754.1 - 1.8e-09 37.0 16.2 1.8e-09 37.0 11.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PLDc_2 PF13091.1 EIM89755.1 - 1.1e-09 38.1 0.0 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIM89755.1 - 1.5e-05 24.6 0.1 0.25 11.1 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Tyr_Deacylase PF02580.11 EIM89756.1 - 6.9e-49 165.5 0.0 8.6e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase WD40 PF00400.27 EIM89757.1 - 2e-54 179.6 26.8 6.2e-11 41.7 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 EIM89757.1 - 0.00013 21.4 1.4 0.00023 20.7 1.0 1.4 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EIM89757.1 - 0.00049 18.9 6.4 1.6 7.4 0.0 4.6 2 2 3 5 5 5 3 Nup133 N terminal like Nup160 PF11715.3 EIM89757.1 - 0.0012 17.0 14.8 0.057 11.5 0.2 5.6 4 1 2 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EIM89757.1 - 0.023 14.4 2.3 0.046 13.4 1.6 1.5 1 0 0 1 1 1 0 F-box-like PQQ_3 PF13570.1 EIM89757.1 - 0.035 14.3 0.5 9.8 6.6 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Pro_isomerase PF00160.16 EIM89758.1 - 6.1e-51 172.6 0.0 6.8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 EIM89759.1 - 3e-06 26.8 1.2 8e-06 25.4 0.8 1.8 1 1 0 1 1 1 1 F-box-like Nuc_sug_transp PF04142.10 EIM89760.1 - 3.1e-78 262.2 7.8 4.4e-78 261.7 5.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIM89760.1 - 5.5e-10 39.4 3.2 5.5e-10 39.4 2.2 2.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EIM89760.1 - 1.3e-06 28.1 0.6 1.3e-06 28.1 0.4 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIM89760.1 - 3.6e-06 26.1 14.4 7.2e-06 25.1 10.0 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIM89760.1 - 0.00011 22.2 3.2 0.00011 22.2 2.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family Mit_ribos_Mrp51 PF11709.3 EIM89761.1 - 2.6e-16 59.7 6.6 1e-08 34.7 0.4 2.7 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit AAA_12 PF13087.1 EIM89763.1 - 3e-44 150.8 0.0 4.5e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ribosomal_S13_N PF08069.7 EIM89763.1 - 0.0065 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Viral_helicase1 PF01443.13 EIM89763.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EIM89763.1 - 0.085 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Rep_fac-A_C PF08646.5 EIM89766.1 - 7.9e-48 161.8 3.2 3.8e-47 159.6 0.3 2.5 3 0 0 3 3 3 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EIM89766.1 - 1.2e-23 82.7 1.9 1.4e-23 82.6 0.3 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EIM89766.1 - 1.4e-13 50.4 1.1 5.1e-12 45.4 0.1 2.7 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain POT1 PF02765.12 EIM89766.1 - 0.022 14.7 0.1 0.23 11.3 0.0 2.6 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 Zn_Tnp_IS1 PF03811.8 EIM89766.1 - 0.48 9.9 2.5 9.6 5.8 0.5 2.5 2 0 0 2 2 2 0 InsA N-terminal domain IDO PF01231.13 EIM89767.1 - 1.8e-96 323.1 0.0 2.1e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_C PF13766.1 EIM89768.1 - 5.6e-31 107.1 0.5 2.1e-30 105.2 0.1 2.1 3 0 0 3 3 3 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIM89768.1 - 8.2e-23 80.7 0.0 2.7e-22 79.0 0.0 1.9 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family CAP_GLY PF01302.20 EIM89769.1 - 1.7e-20 72.4 0.2 2.6e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EIM89769.1 - 4.5e-12 45.2 12.3 1.8e-05 24.2 1.1 6.0 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM89769.1 - 1.8e-10 40.4 9.3 1e-06 28.3 0.6 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EIM89769.1 - 2.2e-05 24.0 5.9 1.2 9.3 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EIM89769.1 - 0.00074 19.3 7.4 52 4.7 0.1 6.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EIM89769.1 - 0.0086 15.9 12.7 8.8 6.7 0.0 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat FNIP PF05725.7 EIM89769.1 - 0.027 14.4 1.3 0.57 10.1 0.0 3.6 2 1 1 3 3 3 0 FNIP Repeat Aminotran_5 PF00266.14 EIM89770.1 - 2.2e-96 322.8 0.0 2.6e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIM89770.1 - 9.8e-10 38.0 0.1 1.4e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIM89770.1 - 1.3e-05 24.3 0.1 0.00024 20.2 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIM89770.1 - 7.2e-05 21.2 0.0 0.00011 20.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.17 EIM89771.1 - 5.9e-29 99.5 0.0 1.2e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89771.1 - 4.7e-22 77.7 0.0 5.7e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89771.1 - 2.7e-17 62.3 0.0 3.1e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIM89771.1 - 0.00014 21.5 0.1 0.042 13.6 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EIM89771.1 - 0.00034 20.4 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIM89771.1 - 0.00035 20.2 0.1 0.0041 16.8 0.0 2.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 EIM89771.1 - 0.14 11.8 0.0 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain PVL_ORF50 PF07768.6 EIM89774.1 - 0.083 12.8 5.0 0.11 12.5 3.4 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family DUF3987 PF13148.1 EIM89774.1 - 0.44 9.0 7.2 0.65 8.4 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tet_JBP PF12851.2 EIM89775.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_6 PF01341.12 EIM89776.1 - 2.2e-112 375.3 3.2 2.8e-112 375.0 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EIM89776.1 - 5.5e-12 45.1 12.1 1.2e-11 44.0 8.4 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1681 PF07933.9 EIM89777.1 - 4.6e-53 179.0 0.0 5.4e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) NIF PF03031.13 EIM89778.1 - 3.8e-21 75.4 0.0 5.9e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EIM89778.1 - 5.7e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Acid_phosphat_B PF03767.9 EIM89778.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) NUDIX PF00293.23 EIM89779.1 - 4.1e-17 62.0 0.5 1.1e-15 57.4 0.0 2.6 2 1 0 2 2 2 1 NUDIX domain NUDIX_4 PF14815.1 EIM89779.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF2890 PF11081.3 EIM89781.1 - 0.0062 16.6 1.8 0.012 15.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 EIM89781.1 - 0.015 13.6 5.6 0.021 13.2 3.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.8 EIM89781.1 - 0.2 11.2 7.2 0.3 10.6 5.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Aminotran_1_2 PF00155.16 EIM89782.1 - 3.7e-31 108.4 0.0 4.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.13 EIM89783.1 - 3.4e-10 39.6 10.6 6.3e-10 38.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-T PF15511.1 EIM89784.1 - 0.03 13.5 10.5 0.031 13.5 7.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Cwf_Cwc_15 PF04889.7 EIM89784.1 - 0.38 10.4 9.9 0.51 10.0 6.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 EIM89784.1 - 4.7 6.6 14.1 6 6.3 9.8 1.1 1 0 0 1 1 1 0 PPP4R2 FLO_LFY PF01698.11 EIM89784.1 - 5.1 5.8 6.4 6.5 5.4 4.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleo_P87 PF07267.6 EIM89784.1 - 6 5.4 6.7 7.4 5.1 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CwfJ_C_1 PF04677.10 EIM89785.1 - 4.7e-30 103.7 0.0 8.7e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIM89785.1 - 6.3e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EIM89785.1 - 1.4e-15 56.4 15.1 2.4e-06 26.9 0.9 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 EIM89785.1 - 1e-06 28.3 14.1 0.024 14.5 0.1 4.2 4 0 0 4 4 4 3 Zinc knuckle eIF3g PF12353.3 EIM89785.1 - 0.002 18.0 9.8 0.71 9.8 0.3 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G DUF4428 PF14471.1 EIM89785.1 - 0.013 15.1 0.8 2.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-CCHC_4 PF14392.1 EIM89785.1 - 0.21 11.2 12.1 0.48 10.1 0.3 3.5 3 0 0 3 3 3 0 Zinc knuckle FYVE_2 PF02318.11 EIM89785.1 - 1.7 8.6 3.2 2.5 8.0 0.5 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-CCHC_3 PF13917.1 EIM89785.1 - 6.1 6.6 12.7 1.8 8.3 0.1 3.4 2 1 1 3 3 3 0 Zinc knuckle COesterase PF00135.23 EIM89787.1 - 6e-62 210.0 0.0 7.1e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM89787.1 - 2.8e-11 43.4 0.1 5.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cupin_2 PF07883.6 EIM89788.1 - 1.3e-30 104.7 0.9 2.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EIM89788.1 - 1.7e-28 98.8 0.0 1.5e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EIM89788.1 - 1.2e-10 40.5 0.0 3.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.9 EIM89788.1 - 1.9e-06 27.9 0.0 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.13 EIM89788.1 - 5.4e-06 26.1 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EIM89788.1 - 7.2e-06 25.7 0.4 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.7 EIM89788.1 - 3.7e-05 23.1 0.0 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein FdtA PF05523.6 EIM89788.1 - 0.00073 19.0 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 WxcM-like, C-terminal 3-HAO PF06052.7 EIM89788.1 - 0.0015 17.9 0.0 0.0089 15.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.1 EIM89788.1 - 0.019 14.4 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Cupin-like domain GPI PF06560.6 EIM89788.1 - 0.039 12.9 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Pirin_C PF05726.8 EIM89788.1 - 0.044 13.8 0.0 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Pirin C-terminal cupin domain DUF3446 PF11928.3 EIM89788.1 - 0.15 12.2 7.9 0.5 10.6 5.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SoxE PF06525.6 EIM89788.1 - 1.8 7.7 4.9 2.2 7.5 1.4 2.1 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Acyl-CoA_dh_1 PF00441.19 EIM89790.1 - 1.8e-41 141.7 0.4 3.4e-41 140.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIM89790.1 - 3e-37 127.6 0.0 5.3e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIM89790.1 - 6.1e-18 64.0 0.1 1.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIM89790.1 - 1.9e-15 57.2 0.0 3.9e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EIM89790.1 - 0.0073 16.6 0.0 0.032 14.5 0.0 2.1 2 1 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Ins_P5_2-kin PF06090.7 EIM89792.1 - 5.1e-55 186.7 0.0 6e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase adh_short_C2 PF13561.1 EIM89793.1 - 3.1e-29 102.4 0.0 3.7e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM89793.1 - 7.6e-25 87.7 0.1 1.2e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM89793.1 - 6.1e-11 42.3 0.0 1.3e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM89793.1 - 6.9e-05 22.3 0.0 0.00057 19.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIM89793.1 - 0.0018 17.2 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GATA PF00320.22 EIM89794.1 - 4.3e-15 54.7 5.0 7e-15 54.0 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EIM89794.1 - 0.00085 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIM89794.1 - 0.0034 17.7 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EIM89794.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold TFR_dimer PF04253.10 EIM89795.1 - 2.2e-12 46.6 0.0 8.5e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EIM89795.1 - 4.3e-12 46.1 0.1 1.2e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EIM89795.1 - 4.4e-06 26.3 0.1 8.8e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EIM89795.1 - 0.0016 18.0 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EIM89796.1 - 5.2e-14 52.3 0.0 2.1e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EIM89796.1 - 1.9e-12 46.8 0.0 6.9e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M20 PF01546.23 EIM89796.1 - 2.6e-05 23.8 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.17 EIM89796.1 - 0.00022 20.8 0.3 0.00048 19.7 0.2 1.5 1 0 0 1 1 1 1 PA domain IMS PF00817.15 EIM89797.1 - 1.8e-41 141.3 0.0 3.6e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIM89797.1 - 4.5e-16 58.9 0.0 3e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIM89797.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif DUF2197 PF09963.4 EIM89797.1 - 0.15 12.0 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) YTH PF04146.10 EIM89798.1 - 1.2e-46 157.7 0.1 1.8e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 YT521-B-like domain F-box-like PF12937.2 EIM89799.1 - 2.1e-07 30.5 3.9 8.4e-07 28.6 2.7 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM89800.1 - 3.3e-09 36.3 0.0 6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM89800.1 - 0.00059 19.4 0.9 0.22 11.2 0.1 2.5 2 0 0 2 2 2 2 F-box domain DASH_Dad3 PF08656.5 EIM89801.1 - 5.6e-22 77.2 0.0 6.9e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 CBF PF03914.12 EIM89801.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 CBF/Mak21 family TIMELESS_C PF05029.8 EIM89802.1 - 0.036 12.9 4.2 0.047 12.6 2.9 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region DUF2890 PF11081.3 EIM89802.1 - 0.27 11.2 9.8 0.41 10.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 EIM89802.1 - 3.6 5.9 9.8 4.7 5.5 6.8 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EIM89802.1 - 9.2 5.1 7.0 13 4.6 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.20 EIM89803.1 - 1.5e-52 178.3 0.0 1.9e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89803.1 - 2.6e-20 72.5 0.0 3.6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM89803.1 - 1.8e-07 30.4 0.0 2.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM89803.1 - 0.0013 18.4 0.3 0.0061 16.3 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 EIM89804.1 - 1.3e-21 75.6 12.7 7.1e-09 35.2 0.0 6.6 7 1 0 7 7 7 4 WD domain, G-beta repeat DPPIV_N PF00930.16 EIM89804.1 - 3.7e-05 22.4 1.9 0.001 17.7 0.6 2.7 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 EIM89804.1 - 0.00032 20.0 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 EIM89804.1 - 0.0031 16.9 0.0 37 3.9 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EIM89804.1 - 0.042 13.5 0.3 2.2 7.9 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Arginase PF00491.16 EIM89805.1 - 1.1e-76 257.7 0.1 1.3e-76 257.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family PFU PF09070.6 EIM89806.1 - 1.4e-37 128.2 0.0 2.7e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EIM89806.1 - 4.2e-32 111.0 0.1 5.7e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EIM89806.1 - 2.6e-30 103.1 13.6 4.6e-05 23.1 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIM89806.1 - 0.00079 19.1 0.0 0.05 13.3 0.0 3.1 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF3816 PF12822.2 EIM89807.1 - 0.12 12.2 5.7 1.5 8.7 4.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) VirB3 PF05101.8 EIM89807.1 - 0.39 10.7 3.1 0.99 9.4 0.6 2.7 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein Sulfate_transp PF00916.15 EIM89807.1 - 1.9 7.4 6.6 0.95 8.4 0.5 2.3 1 1 1 2 2 2 0 Sulfate transporter family DUF996 PF06195.8 EIM89807.1 - 3 7.8 6.9 13 5.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Gtr1_RagA PF04670.7 EIM89808.1 - 7.1e-83 277.2 0.0 1.3e-82 276.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIM89808.1 - 8.7e-07 28.4 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89808.1 - 1.9e-05 25.1 0.0 4.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIM89808.1 - 3.6e-05 23.6 0.0 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EIM89808.1 - 0.00043 19.5 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EIM89808.1 - 0.0074 15.7 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EIM89808.1 - 0.13 11.7 0.5 0.27 10.7 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DMRL_synthase PF00885.14 EIM89809.1 - 4.5e-48 162.5 0.0 2.5e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.7 EIM89810.1 - 1.1e-28 99.5 2.1 3.4e-28 97.9 1.4 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain SR-25 PF10500.4 EIM89810.1 - 0.0098 15.3 32.0 0.0098 15.3 22.2 6.5 1 1 6 7 7 7 1 Nuclear RNA-splicing-associated protein Brix PF04427.13 EIM89811.1 - 3e-38 131.3 0.0 3.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Na_Ca_ex PF01699.19 EIM89813.1 - 7.4e-42 142.2 34.9 5.5e-23 81.1 8.7 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EIM89813.1 - 0.01 15.6 0.9 0.15 11.9 0.3 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) His_Phos_2 PF00328.17 EIM89814.1 - 2.5e-52 178.3 0.0 3e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1776 PF08643.5 EIM89815.1 - 2.1e-17 63.2 0.0 3.1e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF883 PF05957.8 EIM89815.1 - 0.011 16.1 4.7 0.022 15.1 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Mito_fiss_reg PF05308.6 EIM89815.1 - 9.1 5.5 9.6 0.17 11.1 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator CPDase PF07823.6 EIM89816.1 - 5.3e-17 61.9 0.0 7.3e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EIM89816.1 - 1.1e-05 25.2 0.0 0.00014 21.6 0.0 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Hemocyanin_M PF00372.14 EIM89817.1 - 0.18 11.0 0.1 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain WD40 PF00400.27 EIM89820.1 - 5.2e-39 130.7 18.0 2.1e-09 36.8 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 EIM89820.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Elongin_A PF06881.6 EIM89821.1 - 2.9e-13 50.1 0.2 4.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.4 EIM89823.1 - 1.7e-26 93.0 0.1 3.2e-24 85.7 0.1 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family cwf18 PF08315.7 EIM89824.1 - 5.5e-32 110.9 10.5 6.6e-32 110.6 7.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DehI PF10778.4 EIM89824.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI DUF4238 PF14022.1 EIM89824.1 - 0.17 11.1 3.0 2.4 7.3 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) PP2C_C PF07830.8 EIM89824.1 - 1.5 8.9 3.5 11 6.1 0.4 2.2 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain GTP_EFTU PF00009.22 EIM89825.1 - 3.5e-51 173.3 0.0 5.4e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EIM89825.1 - 5.1e-40 135.7 0.2 1e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EIM89825.1 - 1.5e-17 63.1 0.0 3.3e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIM89825.1 - 3.1e-09 36.8 0.1 6.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EIM89825.1 - 4e-05 23.0 0.0 9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EIM89825.1 - 6.4e-05 22.8 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EIM89825.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EIM89825.1 - 0.002 18.5 0.0 0.0045 17.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIM89825.1 - 0.0062 15.7 0.1 0.034 13.3 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit IF-2B PF01008.12 EIM89826.1 - 1.8e-63 214.1 0.0 2.1e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1741 PF08427.5 EIM89826.1 - 0.025 14.0 0.8 0.052 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) Trp_syntA PF00290.15 EIM89827.1 - 2.5e-85 285.1 0.4 3.4e-85 284.7 0.3 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EIM89827.1 - 2.1e-44 152.0 0.1 3.5e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EIM89827.1 - 0.00014 21.2 0.1 0.00032 20.0 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 EIM89827.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Asparaginase PF00710.15 EIM89828.1 - 2.1e-118 394.7 0.0 2.8e-118 394.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EIM89828.1 - 1.3e-13 51.0 0.0 3.6e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM89828.1 - 2.5e-12 45.9 3.7 3.8e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIM89828.1 - 2e-10 39.8 0.1 0.0015 18.6 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIM89828.1 - 1.3e-09 38.0 1.8 6.9e-07 29.3 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIM89828.1 - 1.5e-09 38.0 0.2 1e-06 29.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Csm1 PF12539.3 EIM89829.1 - 0.0069 16.8 0.1 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Activator-TraM PF11657.3 EIM89829.1 - 0.035 13.5 2.2 0.064 12.7 1.2 1.7 1 1 0 1 1 1 0 Transcriptional activator TraM Atg14 PF10186.4 EIM89829.1 - 1.6 7.5 22.6 0.25 10.2 3.6 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1515 PF07439.6 EIM89829.1 - 5.8 6.7 7.7 1.1 9.1 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) KH_1 PF00013.24 EIM89830.1 - 1.6e-39 133.3 6.9 5.1e-15 54.8 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIM89830.1 - 1.9e-30 103.9 11.7 7.6e-10 38.2 0.8 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIM89830.1 - 4.2e-15 55.0 5.1 1.3e-05 24.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIM89830.1 - 2e-06 27.3 1.3 0.03 13.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EIM89830.1 - 0.0016 18.1 5.1 2.8 7.8 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain Rep_fac-A_C PF08646.5 EIM89831.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain UCH PF00443.24 EIM89832.1 - 1.8e-41 142.0 0.2 4e-41 140.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM89832.1 - 1.2e-18 67.5 1.2 2.1e-18 66.7 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIM89832.1 - 8.9e-07 29.2 0.0 0.064 13.6 0.1 3.2 2 0 0 2 2 2 2 DUSP domain ubiquitin PF00240.18 EIM89832.1 - 1.2e-06 27.7 0.2 2.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM89832.1 - 0.0011 18.6 0.4 0.0024 17.5 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RanBP PF00641.13 EIM89832.1 - 0.0019 17.2 2.4 0.0019 17.2 1.7 3.6 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others Gaa1 PF04114.9 EIM89833.1 - 5.5e-68 229.8 7.5 6.7e-66 223.0 5.2 2.2 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component LUC7 PF03194.10 EIM89835.1 - 3.5e-70 236.4 2.6 4.4e-70 236.1 1.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Ada3 PF10198.4 EIM89835.1 - 0.0024 17.6 1.3 0.0061 16.3 0.9 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Atg14 PF10186.4 EIM89835.1 - 0.016 14.1 1.5 0.025 13.5 1.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0242 PF06785.6 EIM89835.1 - 0.032 12.8 1.1 0.041 12.5 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Mnd1 PF03962.10 EIM89835.1 - 0.09 12.4 2.8 0.17 11.5 1.9 1.5 1 0 0 1 1 1 0 Mnd1 family FliT PF05400.8 EIM89835.1 - 0.23 11.9 4.6 2.4 8.6 3.2 2.5 1 1 0 1 1 1 0 Flagellar protein FliT Ank_2 PF12796.2 EIM89836.1 - 1.4e-18 67.0 0.0 3.6e-09 36.8 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM89836.1 - 1.2e-12 48.0 0.2 2.6e-09 37.3 0.0 2.6 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM89836.1 - 2.4e-10 39.6 0.2 0.0044 17.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIM89836.1 - 2.1e-08 34.1 0.0 3.3e-05 23.9 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIM89836.1 - 2.2e-07 30.3 0.0 0.0061 16.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Zip PF02535.17 EIM89836.1 - 0.23 10.4 5.1 0.35 9.8 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.12 EIM89836.1 - 1 8.1 6.4 1.4 7.6 4.4 1.1 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.10 EIM89836.1 - 1.4 8.1 4.7 2.4 7.4 1.2 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Ycf1 PF05758.7 EIM89836.1 - 2.5 5.7 4.3 2.9 5.5 3.0 1.1 1 0 0 1 1 1 0 Ycf1 RNase_H2-Ydr279 PF09468.5 EIM89836.1 - 3.6 6.7 6.5 6.5 5.8 4.5 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Atg14 PF10186.4 EIM89836.1 - 4.2 6.2 10.3 6.1 5.6 7.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FRG1 PF06229.7 EIM89839.1 - 2e-25 89.4 0.1 2e-25 89.4 0.1 1.5 2 0 0 2 2 2 1 FRG1-like family DUF1754 PF08555.5 EIM89839.1 - 0.00087 19.8 9.0 0.1 13.1 2.0 2.3 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.8 EIM89839.1 - 0.0041 17.1 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 Fascin domain KOW PF00467.24 EIM89840.1 - 1.2e-09 37.4 3.5 1.2e-09 37.4 2.4 2.0 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.6 EIM89840.1 - 0.041 12.9 0.8 0.057 12.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) ATP-synt_D PF01813.12 EIM89841.1 - 2.2e-63 213.3 1.5 3.4e-63 212.7 1.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Toxin_39 PF15500.1 EIM89841.1 - 0.11 12.6 0.6 0.3 11.2 0.4 1.7 1 0 0 1 1 1 0 Putative RNase-like toxin Lactonase PF10282.4 EIM89842.1 - 5.3e-10 38.8 0.8 2.5e-06 26.8 0.0 3.3 1 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller RnfC_N PF13375.1 EIM89842.1 - 0.0024 17.5 0.4 0.0079 15.8 0.1 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain LAT PF15234.1 EIM89842.1 - 0.26 10.7 2.2 0.53 9.7 1.5 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Cpn60_TCP1 PF00118.19 EIM89843.1 - 1.9e-139 465.4 9.6 2.1e-139 465.2 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UFD1 PF03152.9 EIM89844.1 - 4.1e-66 221.4 0.0 5.4e-66 221.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EIM89844.1 - 0.034 13.7 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 NMT PF01233.14 EIM89845.1 - 1.9e-77 258.4 0.0 3.1e-77 257.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EIM89845.1 - 1.6e-73 246.2 0.2 6e-73 244.2 0.1 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EIM89845.1 - 1.4e-05 24.9 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM89845.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OGG_N PF07934.7 EIM89846.1 - 1.5e-29 102.3 0.1 2.4e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EIM89846.1 - 7.5e-14 51.9 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIM89846.1 - 0.0018 17.8 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif NPR2 PF06218.6 EIM89847.1 - 6.1e-114 381.0 0.6 6.4e-97 324.9 0.5 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 EIM89847.1 - 0.016 13.7 0.8 2 6.8 0.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RTC PF01137.16 EIM89848.1 - 7.7e-66 221.1 0.0 8.9e-66 220.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIM89848.1 - 4e-32 110.2 0.0 6.2e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ThiF PF00899.16 EIM89849.1 - 1.7e-39 134.7 0.1 7.3e-39 132.7 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EIM89849.1 - 1.3e-22 79.1 0.4 2.6e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EIM89849.1 - 6.2e-21 73.9 0.3 9.8e-21 73.3 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EIM89849.1 - 1.3e-17 62.8 1.1 1.3e-17 62.8 0.8 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EIM89849.1 - 0.0032 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EIM89849.1 - 0.042 13.4 0.7 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 MoeZ/MoeB domain Pyr_redox PF00070.22 EIM89849.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_C PF09358.5 EIM89849.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain ApbA PF02558.11 EIM89849.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EIM89850.1 - 1.9e-12 46.9 0.0 5.8e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM89850.1 - 0.0001 22.3 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EIM89850.1 - 0.00048 20.1 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EIM89850.1 - 0.019 14.8 0.2 0.74 9.7 0.0 2.3 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 EIM89850.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ecm33 PF12454.3 EIM89850.1 - 0.18 11.7 0.4 0.78 9.6 0.1 2.1 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein RRM_5 PF13893.1 EIM89851.1 - 0.0039 16.9 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EIM89851.1 - 0.0064 16.1 3.1 0.017 14.7 2.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EIM89851.1 - 0.024 14.2 0.0 0.072 12.7 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 EIM89851.1 - 0.034 14.1 2.0 0.086 12.8 1.4 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sulf_transp PF04143.9 EIM89852.1 - 2e-16 59.7 12.4 9.8e-12 44.7 2.3 5.1 6 0 0 6 6 6 2 Sulphur transport DUF4341 PF14241.1 EIM89852.1 - 2.3e-08 33.6 8.0 2.3e-08 33.6 5.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) adh_short PF00106.20 EIM89853.1 - 7e-13 48.8 0.2 1.8e-12 47.5 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89853.1 - 3.8e-07 30.1 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM89853.1 - 7.8e-05 22.7 0.1 0.00048 20.1 0.0 2.2 3 0 0 3 3 3 1 NADH(P)-binding KR PF08659.5 EIM89853.1 - 0.024 14.2 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain tRNA_anti-like PF12869.2 EIM89853.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like adh_short PF00106.20 EIM89854.1 - 1.2e-07 31.7 0.3 2.9e-07 30.5 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIM89854.1 - 3.3e-05 23.9 0.3 8.3e-05 22.6 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EIM89854.1 - 7.8e-05 22.5 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM89854.1 - 0.029 14.0 0.1 0.054 13.1 0.1 1.5 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 EIM89854.1 - 0.11 11.8 0.0 0.66 9.3 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF726 PF05277.7 EIM89855.1 - 1.4e-84 283.9 1.9 1.8e-84 283.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.17 EIM89855.1 - 0.029 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EIM89855.1 - 0.047 13.5 0.3 0.047 13.5 0.2 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase family Y_phosphatase3 PF13350.1 EIM89856.1 - 4.2e-45 153.9 0.0 6.6e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EIM89856.1 - 3.9e-11 42.8 0.0 5.8e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EIM89856.1 - 0.00014 21.2 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EIM89856.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIM89856.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.15 EIM89856.1 - 0.045 13.3 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Cyt-b5 PF00173.23 EIM89856.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain LEA_2 PF03168.8 EIM89857.1 - 1.7e-08 34.7 0.1 2.8e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 EIM89857.1 - 0.02 14.1 1.5 0.025 13.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) JmjC PF02373.17 EIM89858.1 - 8.6e-14 51.7 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIM89858.1 - 0.0012 18.3 0.1 0.0022 17.5 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Pkinase PF00069.20 EIM89859.1 - 3.9e-31 108.1 0.0 4.4e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89859.1 - 5.6e-10 38.7 0.0 7.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM89859.1 - 0.00089 19.0 0.0 0.32 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Vac_ImportDeg PF09783.4 EIM89860.1 - 6.1e-42 143.0 0.1 5.9e-39 133.3 0.0 2.4 2 1 0 2 2 2 2 Vacuolar import and degradation protein MFS_1 PF07690.11 EIM89861.1 - 7.3e-55 186.0 42.2 7.3e-55 186.0 29.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM89861.1 - 1.7e-18 66.1 17.0 2.4e-18 65.6 11.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIM89861.1 - 1.5e-14 53.4 11.7 1.5e-14 53.4 8.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EIM89861.1 - 2.9e-08 32.5 25.2 1e-07 30.7 0.8 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein DUF3624 PF12292.3 EIM89861.1 - 0.025 14.9 1.0 0.11 12.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Ras PF00071.17 EIM89862.1 - 3.2e-50 169.6 0.0 3.8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89862.1 - 4.3e-16 59.4 0.0 7.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM89862.1 - 3e-10 39.6 0.0 3.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM89862.1 - 0.0002 20.6 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EIM89862.1 - 0.0049 17.0 0.1 0.04 14.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EIM89862.1 - 0.0059 15.3 1.9 1.2 7.8 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.7 EIM89862.1 - 0.015 14.6 0.6 0.044 13.0 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 EIM89862.1 - 0.042 13.9 0.1 0.11 12.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EIM89862.1 - 0.094 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 EIM89862.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 STAS domain UPF0079 PF02367.12 EIM89862.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 BCS1_N PF08740.6 EIM89863.1 - 3.8e-45 153.7 0.2 5.7e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIM89863.1 - 4.5e-18 65.7 0.0 9.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIM89863.1 - 3.5e-05 23.3 0.0 0.00027 20.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EIM89863.1 - 7.7e-05 23.4 0.0 0.00017 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM89863.1 - 0.00067 19.9 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIM89863.1 - 0.00093 19.2 0.3 0.0035 17.3 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EIM89863.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIM89863.1 - 0.0041 16.6 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EIM89863.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EIM89863.1 - 0.016 15.4 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 EIM89863.1 - 0.016 15.3 0.0 0.051 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIM89863.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EIM89863.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EIM89863.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EIM89863.1 - 0.079 12.0 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EIM89863.1 - 0.083 11.9 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 EIM89863.1 - 0.16 12.2 0.3 0.48 10.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain WBS_methylT PF12589.3 EIM89864.1 - 2.4e-21 76.0 10.0 3.6e-21 75.4 6.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EIM89864.1 - 7.9e-09 35.8 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM89864.1 - 3e-06 27.0 0.0 6.4e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM89864.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM89864.1 - 0.00019 21.8 0.0 0.00061 20.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM89864.1 - 0.0017 18.9 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM89864.1 - 0.0035 17.6 0.0 0.0082 16.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 EIM89864.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.11 EIM89865.1 - 1.1e-35 122.3 0.0 1.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PTP_N PF12453.3 EIM89865.1 - 0.0015 18.0 0.4 0.0015 18.0 0.2 2.1 2 0 0 2 2 2 1 Protein tyrosine phosphatase N terminal NIL PF09383.5 EIM89865.1 - 0.048 13.2 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 NIL domain XAP5 PF04921.9 EIM89866.1 - 6.9e-95 317.1 4.8 6.9e-95 317.1 3.3 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator CortBP2 PF09727.4 EIM89866.1 - 4.1 6.8 18.5 1.3 8.4 7.6 2.8 2 1 1 3 3 3 0 Cortactin-binding protein-2 adh_short PF00106.20 EIM89867.1 - 1.7e-14 54.0 0.2 2.8e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89867.1 - 4.2e-08 33.2 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM89867.1 - 0.00015 21.8 0.1 0.00059 19.8 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EIM89867.1 - 0.0038 16.9 0.1 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EIM89867.1 - 0.02 13.7 0.0 0.049 12.5 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EIM89867.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase tRNA_anti-like PF12869.2 EIM89867.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA_anti-like adh_short PF00106.20 EIM89869.1 - 3.3e-13 49.8 0.4 6.4e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89869.1 - 5.5e-07 29.5 0.0 1.5e-06 28.1 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM89869.1 - 9e-05 22.5 0.3 0.0006 19.8 0.0 2.3 2 1 1 3 3 3 1 NADH(P)-binding KR PF08659.5 EIM89869.1 - 0.0039 16.8 0.1 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM89869.1 - 0.0058 16.0 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIM89870.1 - 2.5e-14 53.5 0.4 5e-14 52.5 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89870.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM89870.1 - 0.00016 21.7 0.1 0.00055 19.9 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM89870.1 - 0.002 17.8 0.2 0.0043 16.7 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM89871.1 - 1.5e-14 54.2 0.2 2.9e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM89871.1 - 5.9e-08 32.7 0.0 9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM89871.1 - 0.0014 18.6 0.1 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EIM89871.1 - 0.0021 17.7 0.2 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EIM89871.1 - 0.02 13.7 0.1 0.063 12.1 0.1 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EIM89872.1 - 2.5e-16 59.8 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM89872.1 - 2.2e-08 33.1 0.0 3.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM89872.1 - 3.9e-07 30.2 0.1 1.4e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM89872.1 - 0.00012 21.0 0.2 0.014 14.3 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM89872.1 - 0.00024 20.4 0.1 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Mito_carr PF00153.22 EIM89873.1 - 4.5e-44 148.0 1.4 1.7e-14 53.2 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.4 EIM89874.1 - 4.9e-18 64.6 13.7 1.9e-08 32.9 0.7 3.7 4 0 0 4 4 4 3 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.17 EIM89875.1 - 3.8e-40 137.9 0.6 5.9e-39 134.0 0.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 CLASP_N PF12348.3 EIM89876.1 - 1e-21 77.3 0.0 3.2e-10 39.7 0.0 5.0 4 0 0 4 4 4 4 CLASP N terminal HEAT_2 PF13646.1 EIM89876.1 - 5.3e-14 52.2 16.8 0.0015 18.7 0.0 8.8 8 1 1 9 9 9 5 HEAT repeats HEAT PF02985.17 EIM89876.1 - 1.2e-11 43.6 15.5 0.0059 16.5 0.0 11.7 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.1 EIM89876.1 - 6.4e-05 23.3 13.1 0.43 11.1 0.0 6.9 6 1 2 8 8 8 2 HEAT-like repeat Arm PF00514.18 EIM89876.1 - 0.0019 17.9 0.9 0.24 11.2 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIM89876.1 - 0.017 14.9 0.0 7.5 6.3 0.0 4.1 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIM89876.1 - 0.077 13.3 0.0 28 5.1 0.0 5.0 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region TAN PF11640.3 EIM89876.1 - 0.089 12.5 1.7 4.5 6.9 0.1 3.9 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.15 EIM89876.1 - 0.11 10.8 0.3 16 3.6 0.0 4.2 6 0 0 6 6 6 0 Adaptin N terminal region FAD_binding_3 PF01494.14 EIM89877.1 - 8.3e-49 166.5 0.0 4.3e-48 164.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIM89877.1 - 1.8e-07 30.6 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM89877.1 - 1.8e-07 31.4 0.2 8.7e-07 29.2 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM89877.1 - 2.5e-07 29.9 0.0 0.00034 19.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM89877.1 - 4.1e-07 29.2 0.4 6.7e-07 28.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM89877.1 - 1.4e-06 28.3 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM89877.1 - 2.7e-06 26.5 0.2 2.2e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIM89877.1 - 1.1e-05 24.7 0.1 2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIM89877.1 - 8.4e-05 22.5 0.1 0.00027 20.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EIM89877.1 - 0.00019 21.2 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 ThiF family HI0933_like PF03486.9 EIM89877.1 - 0.00022 19.8 1.3 0.0013 17.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EIM89877.1 - 0.00022 21.0 0.2 0.019 14.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EIM89877.1 - 0.00027 21.0 0.1 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIM89877.1 - 0.0003 21.1 0.5 0.054 13.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM89877.1 - 0.0034 16.3 1.2 0.0046 15.8 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.5 EIM89877.1 - 0.0096 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase TrkA_N PF02254.13 EIM89877.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 EIM89877.1 - 0.019 13.5 0.5 0.16 10.5 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EIM89877.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 EIM89877.1 - 0.099 12.7 0.3 0.29 11.2 0.0 2.0 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Apc5 PF12862.2 EIM89878.1 - 3.1e-10 39.7 1.8 3.7e-09 36.2 0.6 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EIM89878.1 - 0.00036 20.4 7.5 0.088 12.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat HCV_NS5a PF01506.14 EIM89878.1 - 0.01 15.4 0.5 0.023 14.3 0.3 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor TPR_2 PF07719.12 EIM89878.1 - 0.28 11.1 10.8 0.44 10.5 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM89878.1 - 0.34 11.6 8.0 2.6 8.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NOC3p PF07540.6 EIM89879.1 - 1.5e-25 89.2 0.2 6e-25 87.3 0.0 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EIM89879.1 - 3.5e-24 85.1 2.1 3.3e-23 81.9 0.0 3.1 2 1 0 3 3 3 1 CBF/Mak21 family AAA_11 PF13086.1 EIM89879.1 - 0.042 13.4 2.1 0.089 12.3 1.5 1.5 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 EIM89879.1 - 0.083 12.9 2.9 0.23 11.5 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF4337 PF14235.1 EIM89879.1 - 1.5 8.6 6.4 4.9 6.9 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TEA PF01285.13 EIM89880.1 - 1e-09 38.0 0.9 1e-09 38.0 0.6 1.5 2 0 0 2 2 2 1 TEA/ATTS domain family UEV PF05743.8 EIM89881.1 - 2e-32 111.4 0.0 2e-32 111.4 0.0 2.2 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 EIM89881.1 - 8.3e-28 95.7 0.5 1.4e-27 95.1 0.4 1.4 1 0 0 1 1 1 1 Vps23 core domain MSC PF09402.5 EIM89882.1 - 2.8e-55 187.3 0.0 6.3e-55 186.2 0.0 1.5 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EIM89882.1 - 8e-11 41.3 0.0 2.1e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 HeH/LEM domain DUF3328 PF11807.3 EIM89882.1 - 0.087 12.4 2.5 0.24 11.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) ox_reductase_C PF08635.5 EIM89883.1 - 3.2e-72 240.5 0.3 4.6e-72 240.0 0.2 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIM89883.1 - 3.7e-21 75.8 0.0 6.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIM89883.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF3498 PF12004.3 EIM89884.1 - 0.003 16.7 2.5 0.0033 16.6 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) DUF972 PF06156.8 EIM89884.1 - 0.012 15.9 0.2 0.016 15.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF607 PF04678.8 EIM89884.1 - 0.062 13.2 0.2 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 T2SF PF00482.18 EIM89884.1 - 0.084 12.7 0.2 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F AHH PF14412.1 EIM89884.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Matrilin_ccoil PF10393.4 EIM89884.1 - 0.16 11.3 1.7 0.26 10.6 1.2 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Uds1 PF15456.1 EIM89884.1 - 0.34 10.9 5.7 0.54 10.2 3.9 1.3 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_Maf PF03131.12 EIM89884.1 - 0.83 9.9 7.9 1.2 9.4 5.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2681 PF10883.3 EIM89884.1 - 1.8 8.8 4.9 2.7 8.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) IncA PF04156.9 EIM89884.1 - 2.1 7.9 6.6 3 7.4 4.6 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EIM89884.1 - 6.4 6.3 8.9 9.2 5.8 6.2 1.2 1 0 0 1 1 1 0 Septum formation initiator PIG-Y PF15159.1 EIM89886.1 - 1.1e-07 31.9 4.3 1.4e-07 31.6 3.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.10 EIM89886.1 - 0.38 10.2 2.6 0.35 10.3 0.3 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III Sfi1 PF08457.5 EIM89888.1 - 1.6e-34 119.2 109.9 2.3e-24 85.7 44.4 3.4 1 1 2 3 3 3 3 Sfi1 spindle body protein DUF1948 PF09185.5 EIM89888.1 - 0.064 12.9 6.1 0.025 14.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) CLTH PF10607.4 EIM89889.1 - 8.9e-18 64.3 0.0 1.9e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EIM89889.1 - 1.5e-17 63.0 1.2 4.1e-17 61.6 0.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EIM89889.1 - 0.00019 20.7 2.5 0.00037 19.7 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EIM89889.1 - 0.013 15.3 0.4 0.028 14.2 0.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EIM89889.1 - 0.029 14.4 0.8 0.064 13.2 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM89889.1 - 0.038 13.8 0.7 0.098 12.5 0.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM89889.1 - 0.044 13.5 0.4 0.098 12.4 0.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM89889.1 - 0.047 13.3 0.8 0.091 12.4 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HMG_box PF00505.14 EIM89889.1 - 0.061 13.6 0.2 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box zf-C3HC4_3 PF13920.1 EIM89889.1 - 0.073 12.7 0.4 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMCO5 PF14992.1 EIM89889.1 - 0.089 11.9 1.3 0.12 11.4 0.9 1.2 1 0 0 1 1 1 0 TMCO5 family zf-Nse PF11789.3 EIM89889.1 - 0.09 12.3 1.4 0.19 11.2 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HMG_box_2 PF09011.5 EIM89889.1 - 0.11 12.8 0.1 0.35 11.2 0.1 1.7 2 0 0 2 2 2 0 HMG-box domain WD40 PF00400.27 EIM89890.1 - 0.0059 16.4 7.0 0.21 11.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Pirin PF02678.11 EIM89891.1 - 2.8e-31 107.5 0.1 5.3e-31 106.6 0.0 1.5 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EIM89891.1 - 1.5e-24 86.0 0.0 4.4e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EIM89891.1 - 0.033 13.6 1.2 0.064 12.7 0.4 1.8 2 0 0 2 2 2 0 Cupin domain AA_permease PF00324.16 EIM89892.1 - 1.3e-124 416.1 36.7 1.6e-124 415.8 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM89892.1 - 4e-28 98.1 41.0 8.7e-28 97.0 28.4 1.5 1 1 0 1 1 1 1 Amino acid permease VirB3 PF05101.8 EIM89892.1 - 0.69 9.9 4.6 0.42 10.6 0.4 2.9 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein ECH PF00378.15 EIM89893.1 - 5.6e-22 78.0 0.0 7.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HEAT_2 PF13646.1 EIM89894.1 - 0.00077 19.6 0.1 0.16 12.2 0.0 3.2 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 EIM89894.1 - 0.31 10.9 2.0 5.1 7.0 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EIM89895.1 - 1.5e-131 439.2 5.7 2.1e-131 438.8 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIM89895.1 - 2.4e-25 89.3 2.3 4.8e-24 85.1 0.1 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIM89895.1 - 1.5e-14 54.0 5.4 7.4e-08 32.5 0.2 5.0 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EIM89895.1 - 2.9e-09 36.2 1.6 0.023 14.7 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EIM89895.1 - 0.00021 21.6 0.2 7 7.2 0.0 5.6 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 EIM89895.1 - 0.0017 18.0 0.4 9.1 6.2 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EIM89895.1 - 0.066 12.5 0.1 2.8 7.2 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal DUF4477 PF14780.1 EIM89896.1 - 1.7e-07 30.8 0.0 2.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Cu_bind_like PF02298.12 EIM89897.1 - 3.2e-05 23.6 0.8 7.7e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Pyr_redox_2 PF07992.9 EIM89899.1 - 3.6e-08 33.5 0.1 3.3e-07 30.4 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM89899.1 - 0.00034 20.4 0.0 0.039 13.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.10 EIM89899.1 - 0.0071 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain DAO PF01266.19 EIM89899.1 - 0.0084 15.0 0.0 0.2 10.5 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM89899.1 - 0.022 13.8 0.0 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EIM89899.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EIM89899.1 - 0.033 14.2 0.4 0.91 9.5 0.1 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM89899.1 - 0.034 12.6 0.1 0.11 10.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EIM89899.1 - 0.069 11.7 0.1 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EIM89899.1 - 0.08 12.9 0.2 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIM89899.1 - 0.088 11.6 0.0 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EIM89899.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DcpS_C PF11969.3 EIM89900.1 - 2.9e-12 46.8 1.2 5.2e-12 46.0 0.2 1.9 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIM89900.1 - 4.4e-10 39.9 0.0 9.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF2630 PF10944.3 EIM89900.1 - 0.014 15.4 0.3 0.014 15.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) zf-C2H2_2 PF12756.2 EIM89900.1 - 0.35 11.0 2.4 1.1 9.4 1.6 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FadA PF09403.5 EIM89900.1 - 0.64 10.0 3.7 0.29 11.1 0.5 1.9 2 0 0 2 2 2 0 Adhesion protein FadA Siah-Interact_N PF09032.6 EIM89900.1 - 9.9 6.2 8.2 1.8 8.6 1.0 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal BTB PF00651.26 EIM89901.1 - 0.00049 20.0 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Rib PF08428.5 EIM89901.1 - 0.16 11.7 0.2 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Rib/alpha-like repeat RabGAP-TBC PF00566.13 EIM89902.1 - 5.1e-40 137.2 5.0 4.2e-38 130.9 0.6 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 EIM89902.1 - 2.6e-06 26.8 0.0 0.03 13.6 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3548) Lung_7-TM_R PF06814.8 EIM89902.1 - 0.06 12.2 0.2 0.091 11.6 0.2 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor DUF1264 PF06884.6 EIM89904.1 - 8.6e-69 230.3 0.2 1.1e-68 230.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NAC PF01849.13 EIM89905.1 - 5.1e-22 77.1 0.0 9.8e-22 76.2 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EIM89905.1 - 0.0068 16.2 1.2 0.012 15.4 0.2 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EIM89905.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_11 PF08241.7 EIM89906.1 - 0.00021 21.7 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM89906.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIM89906.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain F420_ligase PF01996.11 EIM89906.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Methyltransf_31 PF13847.1 EIM89906.1 - 0.031 13.8 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM89906.1 - 0.079 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.11 EIM89907.1 - 3.6e-28 98.3 0.0 4.2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIM89907.1 - 0.04 13.1 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 P5CR_dimer PF14748.1 EIM89908.1 - 4.7e-40 135.9 1.6 9.3e-40 134.9 1.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EIM89908.1 - 1.1e-12 48.1 0.1 3.8e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 EIM89911.1 - 1.2e-44 151.7 0.0 4.5e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM89911.1 - 6.9e-09 35.5 0.1 2.1e-08 33.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM89911.1 - 6.9e-08 32.5 0.1 2.7e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIM89911.1 - 1.8e-07 31.3 0.4 2e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EIM89911.1 - 3.1e-06 26.3 0.1 6.6e-06 25.2 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIM89911.1 - 7e-06 26.2 2.9 0.00035 20.6 0.3 2.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EIM89911.1 - 2.6e-05 24.1 0.0 0.0006 19.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EIM89911.1 - 8.7e-05 22.5 0.5 0.00037 20.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EIM89911.1 - 0.00016 21.3 0.1 0.00044 19.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIM89911.1 - 0.00074 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIM89911.1 - 0.00078 20.2 0.0 0.0044 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EIM89911.1 - 0.00095 18.9 0.1 0.0066 16.1 0.0 2.4 3 0 0 3 3 2 1 NTPase RNA_helicase PF00910.17 EIM89911.1 - 0.001 19.2 0.0 0.0049 17.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EIM89911.1 - 0.0013 18.3 0.1 0.054 13.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EIM89911.1 - 0.0014 18.9 0.0 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIM89911.1 - 0.0025 16.5 0.0 0.005 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EIM89911.1 - 0.0027 17.1 0.7 0.0099 15.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein UPF0079 PF02367.12 EIM89911.1 - 0.0028 17.2 0.1 0.023 14.3 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIM89911.1 - 0.0037 16.7 3.8 0.013 14.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.1 EIM89911.1 - 0.0045 16.5 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIM89911.1 - 0.0062 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EIM89911.1 - 0.0071 15.5 0.1 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EIM89911.1 - 0.0072 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIM89911.1 - 0.0083 16.4 0.1 0.77 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM89911.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIM89911.1 - 0.013 15.0 0.1 0.033 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM89911.1 - 0.014 15.1 0.9 0.23 11.0 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase Zeta_toxin PF06414.7 EIM89911.1 - 0.018 14.1 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.11 EIM89911.1 - 0.023 13.5 0.0 0.072 11.8 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.13 EIM89911.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.22 EIM89911.1 - 0.041 14.1 0.1 0.7 10.1 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.21 EIM89911.1 - 0.074 12.5 0.1 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EIM89911.1 - 0.084 11.9 0.6 0.4 9.7 0.0 2.2 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EIM89911.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.17 EIM89912.1 - 9.5e-11 41.1 0.0 2.5e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM89912.1 - 3.9e-09 36.3 0.0 5.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM89912.1 - 3.4e-05 23.6 0.0 8.6e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBN2_3 PF14244.1 EIM89913.1 - 0.00011 21.8 0.0 0.00071 19.1 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIM89913.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MSP1_C PF07462.6 EIM89913.1 - 1.7 6.9 3.4 1.9 6.8 2.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCHC_5 PF14787.1 EIM89914.1 - 0.0015 18.0 0.3 0.004 16.6 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Chitin_synth_1 PF01644.12 EIM89916.1 - 9.4e-66 220.6 0.2 1.5e-65 219.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIM89916.1 - 2.1e-27 94.5 0.2 4.7e-27 93.4 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIM89916.1 - 4.9e-26 91.2 0.0 3.6e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM89916.1 - 3.4e-11 43.2 0.1 3.4e-11 43.2 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIM89916.1 - 3.3e-08 33.6 0.0 9.3e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Abhydrolase_3 PF07859.8 EIM89917.1 - 2e-13 50.4 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM89917.1 - 7.8e-10 38.3 0.0 0.00029 20.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM89917.1 - 5.3e-09 35.9 0.0 9.9e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIM89917.1 - 3.6e-06 25.7 0.0 3.5e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EIM89917.1 - 5.7e-05 23.1 0.2 8.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIM89917.1 - 0.00083 18.3 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIM89917.1 - 0.00096 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 EIM89917.1 - 0.0028 16.4 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_1 PF00561.15 EIM89917.1 - 0.07 12.6 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.3 EIM89917.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF1777 PF08648.7 EIM89918.1 - 1.3e-15 57.5 48.1 1.3e-15 57.5 33.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIM89918.1 - 6 5.2 20.1 6.7 5.0 13.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SUI1 PF01253.17 EIM89919.1 - 3.4e-30 103.6 0.6 4.1e-30 103.4 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 EIM89919.1 - 0.0034 16.1 0.0 0.0034 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 PPP4R2 PF09184.6 EIM89920.1 - 3.9e-21 75.8 6.9 2.1e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 PPP4R2 PAP2 PF01569.16 EIM89921.1 - 1.2e-27 96.0 2.0 1.2e-27 96.0 1.4 1.8 2 1 0 2 2 2 1 PAP2 superfamily DUF1705 PF08019.7 EIM89921.1 - 0.063 12.7 0.4 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) DUF4131 PF13567.1 EIM89921.1 - 0.48 9.8 5.8 3.5 7.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HCO3_cotransp PF00955.16 EIM89921.1 - 0.65 8.5 2.9 0.19 10.3 0.2 1.4 2 0 0 2 2 2 0 HCO3- transporter family Ribosomal_S21e PF01249.13 EIM89922.1 - 6.3e-33 112.5 0.1 6.8e-33 112.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NTF2 PF02136.15 EIM89922.1 - 0.086 13.2 0.0 0.099 13.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Hamartin PF04388.7 EIM89923.1 - 7.5e-12 44.7 19.1 1.4e-10 40.5 13.3 2.5 1 1 0 1 1 1 1 Hamartin protein Filament PF00038.16 EIM89923.1 - 0.073 12.5 40.1 0.037 13.4 23.6 2.7 1 1 1 2 2 2 0 Intermediate filament protein Turandot PF07240.6 EIM89923.1 - 0.14 11.6 4.5 0.2 11.1 0.2 2.7 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Reo_sigmaC PF04582.7 EIM89923.1 - 0.25 10.4 2.1 0.37 9.9 0.3 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EIM89923.1 - 1.3 9.2 8.8 0.18 12.0 0.6 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HSP90 PF00183.13 EIM89924.1 - 1e-247 822.7 31.2 1.3e-247 822.4 21.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EIM89924.1 - 6.6e-12 45.1 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIM89924.1 - 6.6e-11 42.0 0.1 6.6e-11 42.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.17 EIM89924.1 - 0.073 12.2 0.2 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase Peptidase_C37 PF05416.7 EIM89924.1 - 1.7 6.8 9.6 1.4 7.1 0.2 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase TRAP_alpha PF03896.11 EIM89924.1 - 3.5 6.5 10.9 0.5 9.3 4.4 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Aminotran_5 PF00266.14 EIM89926.1 - 2.2e-28 99.0 0.0 3.3e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SnoaL_2 PF12680.2 EIM89927.1 - 1.7e-06 28.3 0.0 2.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EIM89927.1 - 5.6e-06 26.5 0.0 7.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 EIM89927.1 - 0.0037 17.1 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Mtr2 PF10429.4 EIM89927.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 NmrA PF05368.8 EIM89928.1 - 2.3e-25 89.2 0.0 2.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM89928.1 - 7e-17 62.0 0.2 9.1e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIM89928.1 - 3.9e-07 29.4 0.1 5.5e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIM89928.1 - 2.4e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIM89928.1 - 0.00038 20.4 0.1 0.00056 19.8 0.1 1.2 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EIM89928.1 - 0.0011 17.7 0.1 0.0016 17.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM89928.1 - 0.002 17.6 0.0 0.089 12.2 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family OCD_Mu_crystall PF02423.10 EIM89928.1 - 0.0056 15.4 0.1 0.0083 14.9 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.11 EIM89928.1 - 0.047 14.0 0.1 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIM89928.1 - 0.056 12.5 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.16 EIM89929.1 - 1.6e-71 240.4 0.0 1.8e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EIM89930.1 - 2.4e-25 88.4 0.2 4.8e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM89930.1 - 1.9e-19 69.5 0.2 2.7e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIM89930.1 - 0.0051 16.8 0.1 0.0076 16.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 EIM89930.1 - 0.0074 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TPP_enzyme_C PF02775.16 EIM89930.1 - 0.08 12.5 0.2 1.7 8.1 0.0 2.6 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_97 PF10566.4 EIM89930.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 1 0 1 1 1 0 Glycoside hydrolase 97 Dynamin_M PF01031.15 EIM89931.1 - 5.6e-105 350.3 0.0 1e-104 349.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIM89931.1 - 2.4e-55 186.9 0.0 5.4e-55 185.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIM89931.1 - 3.9e-28 97.1 2.1 3.9e-28 97.1 1.5 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIM89931.1 - 0.0096 15.8 0.4 0.099 12.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIM89931.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein NTF2 PF02136.15 EIM89932.1 - 2.5e-32 111.7 0.0 2.8e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain FAD_binding_3 PF01494.14 EIM89934.1 - 4.7e-78 262.7 0.0 5.9e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM89934.1 - 3.3e-06 26.8 0.0 7.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EIM89934.1 - 2.6e-05 23.3 0.4 8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM89934.1 - 3.6e-05 23.7 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM89934.1 - 0.00019 20.6 0.0 0.00036 19.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIM89934.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM89934.1 - 0.0015 18.4 0.1 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EIM89934.1 - 0.003 17.6 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EIM89934.1 - 0.0034 16.7 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EIM89934.1 - 0.0038 15.7 0.0 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM89934.1 - 0.0043 17.1 0.0 0.0073 16.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIM89934.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EIM89934.1 - 0.009 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIM89934.1 - 0.017 14.0 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM89934.1 - 0.03 13.1 0.1 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Methyltransf_1N PF02870.10 EIM89934.1 - 0.034 14.7 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain AlaDh_PNT_C PF01262.16 EIM89934.1 - 0.065 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EIM89934.1 - 0.091 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DEAD PF00270.24 EIM89935.1 - 1.1e-46 158.4 0.0 1.9e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM89935.1 - 2.3e-27 94.6 0.0 6.1e-27 93.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM89935.1 - 9.8e-05 22.2 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_WhiA PF02650.9 EIM89935.1 - 0.05 13.9 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TRAPPC10 PF12584.3 EIM89936.1 - 9.8e-29 99.7 0.0 2.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 BNR_2 PF13088.1 EIM89937.1 - 3.3e-18 65.9 1.0 1.4e-08 34.3 0.3 2.2 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EIM89937.1 - 5.5e-09 34.5 18.6 0.06 13.1 0.5 5.4 4 0 0 4 4 4 4 BNR/Asp-box repeat BNR_3 PF13859.1 EIM89937.1 - 1.9e-06 27.1 1.9 2.8e-06 26.6 1.3 1.2 1 0 0 1 1 1 1 BNR repeat-like domain ALG3 PF05208.8 EIM89938.1 - 2.9e-121 405.1 7.9 3.4e-121 404.9 5.5 1.0 1 0 0 1 1 1 1 ALG3 protein gag-asp_proteas PF13975.1 EIM89939.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Arv1 PF04161.8 EIM89940.1 - 1.3 8.8 5.8 1.9 8.3 4.0 1.2 1 0 0 1 1 1 0 Arv1-like family Planc_extracel PF07595.7 EIM89940.1 - 1.8 8.4 10.0 2.2 8.0 0.7 3.7 4 0 0 4 4 4 0 Planctomycete extracellular CstA PF02554.9 EIM89940.1 - 8.9 4.8 13.3 21 3.5 9.2 1.5 1 1 0 1 1 1 0 Carbon starvation protein CstA Ist1 PF03398.9 EIM89941.1 - 1.9e-26 92.4 0.0 3.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 EIM89941.1 - 1.6e-15 57.1 0.0 4.6e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PIG-H PF10181.4 EIM89942.1 - 2.2e-12 46.4 0.0 3.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Cellulase PF00150.13 EIM89943.1 - 5e-13 48.8 0.1 1.8e-12 47.0 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EIM89944.1 - 7e-11 41.6 13.0 7e-11 41.6 9.0 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain DOMON PF03351.12 EIM89944.1 - 0.0058 16.5 0.1 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 DOMON domain Ribosomal_L7Ae PF01248.21 EIM89945.1 - 1.8e-25 88.2 0.1 2.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIM89945.1 - 0.00044 20.1 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EIM89945.1 - 0.0086 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RTBV_P46 PF06216.6 EIM89945.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein UQ_con PF00179.21 EIM89946.1 - 2.1e-49 166.5 0.0 2.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM89946.1 - 0.00049 19.8 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIM89946.1 - 0.059 13.2 0.8 0.079 12.8 0.5 1.6 1 1 0 1 1 1 0 RWD domain Proteasome PF00227.21 EIM89947.1 - 1.5e-50 171.1 0.1 1.9e-50 170.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Syja_N PF02383.13 EIM89948.1 - 9e-88 294.0 0.0 1.4e-87 293.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EIM89948.1 - 5.7e-26 90.1 0.0 1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Myosin_TH1 PF06017.8 EIM89948.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Myosin tail LIM PF00412.17 EIM89949.1 - 2.4e-13 49.9 27.8 3.6e-11 42.9 4.2 4.5 5 0 0 5 5 5 3 LIM domain Gly-zipper_YMGG PF13441.1 EIM89950.1 - 0.12 11.8 6.5 0.32 10.5 4.5 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper Syndecan PF01034.15 EIM89950.1 - 0.16 11.6 0.2 0.32 10.6 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Fungal_trans PF04082.13 EIM89951.1 - 2.3e-26 92.2 0.0 4.8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM89951.1 - 1.3e-10 41.0 3.6 2.4e-10 40.1 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_synt_2 PF02719.10 EIM89951.1 - 0.23 10.3 0.1 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-DHHC PF01529.15 EIM89952.1 - 8e-40 136.0 2.2 1.2e-39 135.4 1.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3816 PF12822.2 EIM89952.1 - 0.56 10.0 9.5 0.2 11.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) Lactamase_B PF00753.22 EIM89953.1 - 1.8e-16 60.3 1.5 5.4e-16 58.8 1.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM89953.1 - 4.5e-07 29.6 0.2 6.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_6 PF08030.7 EIM89953.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain F-box-like PF12937.2 EIM89954.1 - 0.00084 19.0 1.8 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like Isochorismatase PF00857.15 EIM89955.1 - 2.7e-22 79.5 0.0 5.5e-22 78.5 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Pyr_redox_2 PF07992.9 EIM89956.1 - 4.5e-41 140.9 0.3 9e-41 139.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIM89956.1 - 1.2e-34 118.6 0.1 6e-34 116.3 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIM89956.1 - 9.5e-19 67.5 4.8 8.9e-18 64.4 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM89956.1 - 2.4e-13 50.6 0.0 2.6e-07 30.9 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM89956.1 - 6.4e-09 35.3 0.0 8.3e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM89956.1 - 2.4e-08 32.8 4.0 0.003 16.1 0.0 3.2 3 1 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 EIM89956.1 - 1.8e-06 27.1 0.0 3.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EIM89956.1 - 0.00052 18.9 3.9 0.0077 15.1 1.6 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EIM89956.1 - 0.00072 18.5 9.8 0.034 13.0 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.17 EIM89956.1 - 0.0023 16.8 3.4 0.0039 16.0 0.6 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIM89956.1 - 0.025 14.3 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIM89956.1 - 0.043 12.9 2.6 0.045 12.8 0.6 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EIM89956.1 - 0.064 12.3 9.0 7.8 5.4 0.0 4.0 3 1 1 4 4 4 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EIM89956.1 - 0.13 11.9 1.4 1.1 8.9 0.0 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EIM89956.1 - 0.24 11.0 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIM89956.1 - 0.96 9.5 6.8 0.071 13.1 0.7 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MIF4G PF02854.14 EIM89957.1 - 3.9e-29 101.5 1.2 4.2e-28 98.2 0.0 2.8 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EIM89957.1 - 2.3e-25 88.4 0.2 5.8e-25 87.1 0.1 1.7 1 0 0 1 1 1 1 MA3 domain DUF1195 PF06708.6 EIM89957.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Sterol-sensing PF12349.3 EIM89959.1 - 5.1e-35 120.2 4.9 5.1e-35 120.2 3.4 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIM89959.1 - 9.7e-13 46.9 0.2 1.5e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Patched family zf-ribbon_3 PF13248.1 EIM89959.1 - 0.033 13.4 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Biotin_lipoyl PF00364.17 EIM89960.1 - 1.7e-19 69.2 0.8 3.8e-19 68.0 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EIM89960.1 - 4.4e-08 32.6 0.1 4.4e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 e3 binding domain Endostatin PF06482.6 EIM89960.1 - 0.0024 17.3 0.4 0.0041 16.5 0.3 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Biotin_lipoyl_2 PF13533.1 EIM89960.1 - 0.068 12.8 3.3 0.65 9.6 0.0 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like PI-PLC-X PF00388.14 EIM89961.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF389 PF04087.9 EIM89963.1 - 0.12 12.3 0.2 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF389) PsaM PF07465.8 EIM89963.1 - 0.51 9.9 4.2 1.1 8.9 2.1 2.1 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Fe-ADH PF00465.14 EIM89964.1 - 8.8e-77 258.2 3.7 1e-76 258.0 2.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIM89964.1 - 1.9e-17 63.4 0.6 2.6e-17 62.9 0.4 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AIRC PF00731.15 EIM89964.1 - 0.059 12.6 2.0 0.081 12.1 0.1 2.0 2 0 0 2 2 2 0 AIR carboxylase Rad1 PF02144.11 EIM89965.1 - 5.4e-62 209.0 0.0 7.6e-61 205.2 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF3246 PF11596.3 EIM89965.1 - 0.016 14.4 2.7 0.04 13.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SnoaL_2 PF12680.2 EIM89966.1 - 1.5e-05 25.3 0.0 2.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EIM89966.1 - 0.0038 17.1 0.1 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EIM89966.1 - 0.0044 17.2 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.15 EIM89966.1 - 0.0048 17.2 0.0 0.0056 17.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.7 EIM89966.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Flavokinase PF01687.12 EIM89966.1 - 0.055 13.3 0.1 5.4 6.9 0.0 2.1 1 1 1 2 2 2 0 Riboflavin kinase HlyD_2 PF12700.2 EIM89966.1 - 0.096 11.8 0.1 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein FAD_binding_3 PF01494.14 EIM89967.1 - 3.4e-78 263.2 0.0 4.2e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM89967.1 - 2.1e-06 27.4 0.0 4.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EIM89967.1 - 2.9e-05 23.1 0.5 8.1e-05 21.6 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM89967.1 - 3.6e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM89967.1 - 0.00019 20.6 0.0 0.00036 19.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIM89967.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM89967.1 - 0.0016 18.3 0.1 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EIM89967.1 - 0.0031 17.5 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EIM89967.1 - 0.0036 16.7 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EIM89967.1 - 0.0038 15.7 0.0 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIM89967.1 - 0.0041 17.1 0.0 0.0074 16.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIM89967.1 - 0.0068 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EIM89967.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIM89967.1 - 0.017 14.0 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM89967.1 - 0.03 13.1 0.1 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Methyltransf_1N PF02870.10 EIM89967.1 - 0.034 14.7 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain AlaDh_PNT_C PF01262.16 EIM89967.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EIM89967.1 - 0.091 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIM89967.1 - 0.13 10.8 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ras PF00071.17 EIM89968.1 - 1.7e-61 206.3 0.2 2e-61 206.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM89968.1 - 1.8e-20 73.6 0.0 2.5e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM89968.1 - 3.3e-12 45.9 0.0 4.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIM89968.1 - 2.1e-07 30.8 0.1 3.2e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIM89968.1 - 1.5e-05 25.1 0.1 3.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EIM89968.1 - 3.8e-05 23.1 0.1 0.00011 21.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIM89968.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EIM89968.1 - 0.0019 17.4 0.0 0.0051 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIM89968.1 - 0.0022 18.0 0.1 0.044 13.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_15 PF13175.1 EIM89968.1 - 0.0029 16.7 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EIM89968.1 - 0.0078 15.4 0.0 0.015 14.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIM89968.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EIM89968.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EIM89968.1 - 0.034 13.4 0.2 0.14 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EIM89968.1 - 0.039 13.8 0.0 0.097 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIM89968.1 - 0.097 12.2 0.1 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain YvfG PF09628.5 EIM89968.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.9 EIM89968.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF718 PF05336.8 EIM89969.1 - 2.9e-30 104.2 0.0 3.2e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) CBM_5_12 PF02839.9 EIM89970.1 - 8.3e-12 44.4 8.4 2.5e-11 42.9 5.8 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain DPBB_1 PF03330.13 EIM89970.1 - 3.2e-09 36.6 0.0 3.2e-09 36.6 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel HDNR PF15115.1 EIM89970.1 - 0.031 14.2 0.1 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function with conserved HDNR motif MGC-24 PF05283.6 EIM89970.1 - 0.051 13.3 16.9 0.07 12.9 11.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Cerato-platanin PF07249.7 EIM89970.1 - 0.054 13.4 0.4 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Cerato-platanin Mucin PF01456.12 EIM89970.1 - 0.11 12.2 37.7 0.18 11.5 26.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 EIM89970.1 - 2.4 7.3 22.7 3.4 6.8 15.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VCBS PF13517.1 EIM89971.1 - 4.7e-23 81.3 27.0 2.8e-08 33.9 0.7 5.6 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EIM89971.1 - 4.1e-15 54.9 15.7 0.061 13.0 0.3 7.3 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EIM89971.1 - 2.4e-06 27.0 12.6 0.11 11.9 0.1 6.6 4 2 3 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 EIM89971.1 - 9.1 5.8 8.5 8.5 5.9 0.1 3.7 4 0 0 4 4 4 0 EF hand CTP_transf_2 PF01467.21 EIM89972.1 - 9.1e-10 38.7 0.1 2.1e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 EIM89972.1 - 0.087 12.4 0.1 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase MARVEL PF01284.18 EIM89973.1 - 0.19 11.5 2.3 0.24 11.2 1.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain SRPRB PF09439.5 EIM89974.1 - 1.6e-19 69.8 0.0 2.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EIM89974.1 - 4.7e-12 45.4 0.0 6.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM89974.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM89974.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIM89974.1 - 0.00055 20.4 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 EIM89974.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM89974.1 - 0.0015 18.5 0.4 0.0028 17.6 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EIM89974.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EIM89974.1 - 0.03 13.7 0.0 1.2 8.5 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Cation_ATPase_C PF00689.16 EIM89974.1 - 0.047 13.2 0.4 0.064 12.7 0.3 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus GPP34 PF05719.6 EIM89974.1 - 0.049 13.6 0.2 0.077 13.0 0.1 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) SKG6 PF08693.5 EIM89974.1 - 0.05 12.9 1.1 0.11 11.8 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Dynamin_N PF00350.18 EIM89974.1 - 0.063 13.1 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 EIM89974.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 EIM89975.1 - 1.3e-65 221.1 0.0 1.5e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM89975.1 - 1e-32 113.2 0.0 1.3e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM89975.1 - 1e-07 31.2 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM89975.1 - 3.8e-05 23.5 0.0 0.0092 15.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIM89975.1 - 0.00053 19.1 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIM89975.1 - 0.039 13.0 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 EIM89975.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Dicty_spore_N PF04562.7 EIM89976.1 - 0.41 10.9 8.7 5.8 7.2 0.5 3.2 2 2 0 2 2 2 0 Dictyostelium spore coat protein, N terminus Utp21 PF04192.7 EIM89977.1 - 1e-62 211.3 1.6 1.6e-62 210.7 1.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EIM89977.1 - 1.3e-22 78.7 12.6 2e-06 27.4 0.0 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM89977.1 - 0.00012 20.9 3.6 0.018 13.7 0.6 3.8 3 2 0 3 3 3 1 Nup133 N terminal like PPPI_inhib PF14895.1 EIM89977.1 - 0.022 13.5 0.2 0.042 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor RL11D PF11088.3 EIM89977.1 - 0.024 14.4 0.7 0.062 13.1 0.5 1.7 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Hira PF07569.6 EIM89977.1 - 0.031 13.4 5.2 0.89 8.7 0.0 4.9 5 1 0 6 6 6 0 TUP1-like enhancer of split F-box-like PF12937.2 EIM89978.1 - 0.0014 18.2 0.3 0.014 15.0 0.0 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIM89978.1 - 0.035 13.7 0.0 0.56 9.9 0.0 2.9 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 EIM89978.1 - 0.36 10.5 1.6 7.9 6.2 0.0 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 EIM89979.1 - 2.9e-32 111.9 4.2 3.6e-32 111.5 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM89979.1 - 3e-13 49.8 2.3 4.1e-13 49.4 1.6 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM89979.1 - 0.0005 19.8 0.6 0.0011 18.7 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIM89979.1 - 0.00063 19.2 0.4 0.00089 18.7 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIM89979.1 - 0.033 13.2 0.1 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Helicase_RecD PF05127.9 EIM89979.1 - 0.097 12.2 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Helicase TMF_TATA_bd PF12325.3 EIM89980.1 - 0.014 15.1 0.3 0.035 13.8 0.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-CCCH PF00642.19 EIM89980.1 - 0.15 11.7 3.1 0.28 10.9 2.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAT1 PF06391.8 EIM89980.1 - 0.26 10.8 1.9 8.6 5.8 0.2 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Abhydrolase_6 PF12697.2 EIM89981.1 - 2.6e-12 47.1 0.6 4.6e-12 46.3 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM89981.1 - 3.1e-06 26.9 0.1 1.6e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM89981.1 - 0.00074 19.3 0.1 0.0026 17.5 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EIM89981.1 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Cutinase RWD PF05773.17 EIM89982.1 - 2e-18 66.3 0.2 3.8e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain Peptidase_C37 PF05416.7 EIM89982.1 - 0.18 10.0 3.1 0.22 9.7 2.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ribosomal_S21 PF01165.15 EIM89983.1 - 1.5e-10 40.3 12.0 1.5e-10 40.3 8.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S21 zf-A20 PF01754.11 EIM89984.1 - 7.4 6.2 7.3 12 5.6 0.1 2.8 3 0 0 3 3 3 0 A20-like zinc finger Cyclin_N PF00134.18 EIM89986.1 - 9.5e-17 60.7 0.2 2.1e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIM89986.1 - 0.00056 19.6 0.4 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EIM89986.1 - 0.0012 18.7 0.5 0.95 9.4 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain DUF3682 PF12446.3 EIM89986.1 - 0.9 9.8 4.0 1.5 9.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SLR1-BP PF07333.7 EIM89987.1 - 1.1 9.5 8.0 7.8 6.8 5.5 2.2 1 1 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) IF-2B PF01008.12 EIM89988.1 - 4.5e-59 199.7 0.0 6.5e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family HrpJ PF07201.6 EIM89988.1 - 0.13 12.3 0.0 0.38 10.7 0.0 1.7 1 1 1 2 2 2 0 HrpJ-like domain Peptidase_M24 PF00557.19 EIM89990.1 - 3.5e-44 150.8 0.0 4.4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EIM89990.1 - 4.5e-05 23.2 5.4 0.0001 22.0 3.7 1.6 1 0 0 1 1 1 1 MYND finger Mu-like_Com PF10122.4 EIM89991.1 - 0.027 13.5 0.3 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com Acyltransferase PF01553.16 EIM89992.1 - 3.4e-11 42.7 0.0 5.8e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Exo_endo_phos PF03372.18 EIM89993.1 - 1.8e-18 67.3 0.1 2.7e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EIM89994.1 - 4.6e-18 65.0 28.9 2e-13 49.8 13.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DAD PF02109.11 EIM89994.1 - 0.062 13.3 0.1 0.062 13.3 0.1 2.0 2 0 0 2 2 2 0 DAD family Cofilin_ADF PF00241.15 EIM89995.1 - 1.3e-11 44.4 0.0 1.5e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Slx4 PF09494.5 EIM89995.1 - 0.027 14.1 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Slx4 endonuclease Colicin-DNase PF12639.2 EIM89995.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF4351 PF14261.1 EIM89995.1 - 0.57 10.0 2.6 10 6.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Mannosyl_trans PF05007.8 EIM89996.1 - 5.6e-70 235.9 10.0 1.9e-69 234.2 7.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EIM89996.1 - 1.9e-11 43.4 0.7 1.9e-11 43.4 0.5 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EIM89996.1 - 6.6e-07 29.0 12.8 6.6e-07 29.0 8.9 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF2029) Arf PF00025.16 EIM89997.1 - 5.5e-68 227.6 0.0 6.2e-68 227.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIM89997.1 - 8.6e-11 41.3 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIM89997.1 - 2.6e-10 39.5 0.3 6.1e-07 28.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIM89997.1 - 3.4e-07 30.2 0.0 1e-06 28.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIM89997.1 - 8.4e-07 29.5 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIM89997.1 - 1.4e-06 27.7 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIM89997.1 - 8.7e-05 21.7 0.0 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM89997.1 - 0.0084 15.5 0.0 0.28 10.5 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIM89997.1 - 0.017 14.6 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Lipase_3 PF01764.20 EIM89998.1 - 2.8e-07 30.2 0.0 6.6e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIM89998.1 - 0.0067 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM89998.1 - 0.014 15.2 0.4 0.024 14.5 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIM89998.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 EIM89998.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Amidohydro_1 PF01979.15 EIM89999.1 - 1.5e-33 116.8 0.0 9.6e-33 114.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIM89999.1 - 1.6e-05 24.3 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIM89999.1 - 2e-05 24.2 0.0 4.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIM89999.1 - 0.0047 16.9 0.1 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase mRNA_cap_enzyme PF01331.14 EIM90002.1 - 4.9e-49 166.6 0.0 7.1e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EIM90002.1 - 8.1e-20 71.1 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EIM90002.1 - 1.4e-06 27.8 0.0 2.3e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Pex14_N PF04695.8 EIM90002.1 - 0.96 9.4 5.6 1.6 8.8 3.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Skp1 PF01466.14 EIM90003.1 - 5.2e-39 132.1 1.6 8.4e-39 131.4 1.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EIM90003.1 - 4.9e-23 80.9 0.2 1.4e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIM90003.1 - 0.0025 17.7 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.9 EIM90003.1 - 0.072 12.7 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF4375 PF14300.1 EIM90003.1 - 0.13 12.2 0.3 0.83 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_L27 PF01016.14 EIM90004.1 - 1.1e-32 111.6 0.7 1.5e-32 111.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.1 EIM90004.1 - 0.0055 15.9 0.0 0.035 13.4 0.0 2.4 2 1 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region IATP PF04568.7 EIM90004.1 - 0.16 12.0 0.2 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF3074 PF11274.3 EIM90005.1 - 3.1e-39 134.5 0.1 4.2e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Gln-synt_C PF00120.19 EIM90006.1 - 6.3e-56 189.3 0.0 5.4e-55 186.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain WD40 PF00400.27 EIM90007.1 - 7.2e-08 32.0 1.4 0.46 10.4 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIM90007.1 - 0.014 14.9 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EIM90007.1 - 0.076 12.6 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 EIM90007.1 - 0.092 12.8 0.2 2.9 8.2 0.0 3.5 4 0 0 4 4 4 0 Two component regulator propeller Rubis-subs-bind PF09273.6 EIM90008.1 - 2.9e-05 24.0 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EIM90008.1 - 0.00012 22.4 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 SET domain DUF202 PF02656.10 EIM90009.1 - 1 9.6 13.7 0.58 10.4 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF202) Asp PF00026.18 EIM90010.1 - 4.9e-35 121.2 1.9 7e-35 120.7 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM90010.1 - 7.8e-05 22.6 0.8 0.00031 20.7 0.5 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM90010.1 - 0.0035 17.8 0.2 9.6 6.7 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease GTP_EFTU_D3 PF03143.12 EIM90010.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain DnaJ PF00226.26 EIM90011.1 - 3.5e-20 71.5 3.4 3.5e-20 71.5 2.4 2.4 2 0 0 2 2 2 1 DnaJ domain RAI16-like PF10257.4 EIM90012.1 - 1.7e-70 237.7 0.3 2.8e-70 237.0 0.2 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2890 PF11081.3 EIM90012.1 - 0.00056 20.0 3.4 0.00056 20.0 2.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) CDC45 PF02724.9 EIM90012.1 - 0.006 14.6 0.6 0.011 13.8 0.4 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EIM90012.1 - 0.023 12.6 5.0 0.037 11.9 3.4 1.2 1 0 0 1 1 1 0 Nop14-like family Glucan_synthase PF02364.10 EIM90013.1 - 0 1357.2 0.0 0 1356.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIM90013.1 - 1.3e-38 131.5 0.0 3.5e-38 130.1 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NmrA PF05368.8 EIM90015.1 - 6.4e-23 81.2 0.0 1.3e-22 80.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90015.1 - 1.9e-13 50.8 0.0 2.9e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EIM90015.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EIM90015.1 - 0.03 13.0 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM90015.1 - 0.04 13.3 0.0 0.095 12.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M49 PF03571.10 EIM90016.1 - 6.4e-195 648.3 0.0 7.6e-195 648.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 GYD PF08734.6 EIM90016.1 - 0.06 13.0 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 GYD domain TPR_12 PF13424.1 EIM90017.1 - 9.9e-10 38.2 1.3 0.11 12.4 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM90017.1 - 0.0013 18.4 0.2 0.76 9.8 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM90017.1 - 0.0022 18.6 0.0 0.0022 18.6 0.0 4.1 3 2 2 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIM90017.1 - 0.0051 16.6 0.5 0.2 11.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM90017.1 - 0.0071 15.9 0.1 4.5 7.0 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM90017.1 - 0.52 11.0 11.4 0.53 11.0 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.13 EIM90018.1 - 3.8e-17 62.4 0.1 1.7e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIM90018.1 - 0.00024 21.4 0.0 0.0007 20.0 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EIM90018.1 - 0.0025 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Pollen_allerg_2 PF01620.11 EIM90018.1 - 0.14 12.4 1.1 0.37 11.0 0.3 2.0 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) GCIP PF13324.1 EIM90019.1 - 4.9e-07 29.2 0.2 2.7e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting ANF_receptor PF01094.23 EIM90019.1 - 0.056 12.2 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region TraI_2 PF07514.6 EIM90019.1 - 0.077 11.7 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative helicase Peptidase_M41 PF01434.13 EIM90020.1 - 4e-69 232.3 0.0 7e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIM90020.1 - 8.1e-43 145.7 0.0 1.8e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM90020.1 - 2.7e-05 24.9 0.0 7.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM90020.1 - 4.2e-05 22.7 0.0 8.3e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EIM90020.1 - 0.00014 20.7 0.0 0.00031 19.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EIM90020.1 - 0.00017 21.0 2.5 0.025 13.9 0.3 2.6 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM90020.1 - 0.00024 21.2 0.5 0.017 15.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIM90020.1 - 0.00026 20.7 0.2 0.0012 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM90020.1 - 0.00038 20.5 0.4 0.018 14.9 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EIM90020.1 - 0.00096 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 EIM90020.1 - 0.00099 18.0 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIM90020.1 - 0.0011 18.6 0.1 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EIM90020.1 - 0.0067 16.1 0.7 0.078 12.6 0.1 2.6 3 0 0 3 3 3 1 NACHT domain IstB_IS21 PF01695.12 EIM90020.1 - 0.013 14.9 0.2 0.034 13.5 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EIM90020.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EIM90020.1 - 0.023 13.8 0.3 0.052 12.6 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EIM90020.1 - 0.037 13.1 0.4 0.18 10.8 0.1 2.0 1 1 0 2 2 2 0 KaiC AAA_28 PF13521.1 EIM90020.1 - 0.038 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM90020.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EIM90020.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIM90020.1 - 0.077 12.4 0.1 0.23 10.8 0.0 1.7 1 1 1 2 2 2 0 Sigma-54 interaction domain Beta_protein PF14350.1 EIM90020.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Beta protein Glyco_transf_54 PF04666.8 EIM90020.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region RTA1 PF04479.8 EIM90022.1 - 2.6e-38 131.7 2.6 6.2e-38 130.5 1.8 1.5 1 1 0 1 1 1 1 RTA1 like protein DUF4389 PF14333.1 EIM90022.1 - 0.032 13.9 1.9 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF3382 PF11862.3 EIM90022.1 - 0.097 12.5 1.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Abi PF02517.11 EIM90022.1 - 1.6 8.9 10.3 0.29 11.2 0.6 2.6 2 2 1 3 3 3 0 CAAX protease self-immunity DUF1227 PF06777.6 EIM90023.1 - 1.1e-59 200.3 0.3 2e-59 199.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EIM90023.1 - 3e-48 163.5 0.0 5.1e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EIM90023.1 - 7.6e-45 152.8 0.0 1.6e-44 151.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EIM90023.1 - 0.0013 17.6 0.0 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 EIM90023.1 - 0.005 16.3 2.2 1.9 7.9 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIM90023.1 - 0.016 15.0 0.1 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM90023.1 - 0.085 12.9 0.0 11 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain MAP7 PF05672.6 EIM90023.1 - 0.77 9.1 7.0 0.16 11.3 1.0 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family FTHFS PF01268.14 EIM90025.1 - 4.6e-256 850.1 0.0 5.8e-256 849.8 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EIM90025.1 - 5.4e-67 223.8 2.2 5.9e-67 223.7 0.3 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIM90025.1 - 2.1e-35 121.2 0.4 5.3e-35 119.9 0.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ABC_tran PF00005.22 EIM90026.1 - 1.2e-10 41.8 0.0 2.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIM90026.1 - 0.00029 20.1 0.0 0.00031 20.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EIM90026.1 - 0.00033 20.5 0.1 0.0021 17.9 0.1 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF1015 PF06245.6 EIM90026.1 - 0.089 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) AAA_21 PF13304.1 EIM90026.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Porin_3 PF01459.17 EIM90027.1 - 3.3e-77 259.4 4.3 3.9e-77 259.2 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF3552 PF12072.3 EIM90028.1 - 0.0013 18.0 0.9 0.0013 18.0 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF3357 PF11837.3 EIM90028.1 - 0.046 13.5 0.4 0.095 12.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Dsh_C PF12316.3 EIM90028.1 - 0.26 11.3 3.4 0.25 11.4 0.6 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2721 PF11026.3 EIM90028.1 - 0.29 10.7 4.8 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2418 PF10332.4 EIM90029.1 - 2.4e-24 85.4 0.4 4.2e-24 84.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) FBPase PF00316.15 EIM90030.1 - 6.1e-129 429.5 0.0 6.9e-129 429.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EIM90030.1 - 0.00047 19.5 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 EIM90031.1 - 1.1e-32 113.1 38.9 1.2e-30 106.4 16.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EIM90031.1 - 1.6 9.1 4.3 1.1 9.6 0.3 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DIOX_N PF14226.1 EIM90032.1 - 3.3e-26 92.1 0.0 4.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM90032.1 - 7.8e-20 71.0 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MBOAT_2 PF13813.1 EIM90033.1 - 1.5e-13 50.6 1.4 1.5e-13 50.6 0.9 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family zf-C2H2 PF00096.21 EIM90034.1 - 2.4e-12 46.4 12.5 1.3e-06 28.4 0.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM90034.1 - 9.6e-11 41.2 10.9 1.4e-05 25.0 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM90034.1 - 8e-10 38.5 19.0 5e-09 36.0 1.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIM90034.1 - 5.7e-06 26.3 0.8 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM90034.1 - 1.1e-05 25.4 0.7 0.0042 17.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIM90034.1 - 0.0035 17.1 10.1 0.013 15.3 0.0 2.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-CGNR PF11706.3 EIM90034.1 - 0.023 14.1 3.7 0.28 10.7 0.6 2.3 2 0 0 2 2 2 0 CGNR zinc finger Toxin_8 PF07365.7 EIM90034.1 - 0.19 11.7 6.3 0.57 10.1 1.3 2.2 1 1 1 2 2 2 0 Alpha conotoxin precursor CHORD PF04968.7 EIM90034.1 - 0.36 11.1 4.3 3.1 8.1 0.6 2.1 1 1 1 2 2 2 0 CHORD zf-C2H2_2 PF12756.2 EIM90034.1 - 0.81 9.8 3.3 2 8.5 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EIM90034.1 - 2.7 7.8 6.3 1.7 8.4 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger Pmp3 PF01679.12 EIM90035.1 - 1.6e-16 59.6 4.7 2.1e-16 59.3 3.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 EIM90035.1 - 0.28 10.5 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE PNGaseA PF12222.3 EIM90036.1 - 4e-81 273.0 5.2 5.5e-81 272.6 3.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A ACP PF06857.6 EIM90036.1 - 0.18 11.7 0.6 0.36 10.7 0.4 1.5 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Kelch_3 PF13415.1 EIM90037.1 - 0.072 13.2 3.8 0.11 12.7 2.6 1.4 1 1 0 1 1 1 0 Galactose oxidase, central domain BNR PF02012.15 EIM90037.1 - 0.31 11.0 0.2 0.31 11.0 0.2 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Peptidase_M20 PF01546.23 EIM90038.1 - 3.1e-08 33.3 0.8 4.6e-08 32.7 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM90038.1 - 1.2e-06 28.2 0.3 2.4e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain HMA PF00403.21 EIM90039.1 - 7.4e-17 61.2 0.3 8.1e-17 61.1 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Toxin-deaminase PF14424.1 EIM90039.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases AA_permease_2 PF13520.1 EIM90040.1 - 2.3e-66 224.1 41.8 2.8e-66 223.8 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIM90040.1 - 4.7e-33 114.2 40.4 1.3e-32 112.7 27.9 1.6 1 1 0 1 1 1 1 Amino acid permease RNase_PH PF01138.16 EIM90041.1 - 1.7e-32 112.4 0.3 2.9e-32 111.7 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 zf-Tim10_DDP PF02953.10 EIM90041.1 - 0.011 15.0 0.2 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger RNase_PH_C PF03725.10 EIM90041.1 - 0.028 14.3 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 DUF2040 PF09745.4 EIM90042.1 - 2.4e-33 114.6 23.4 2.4e-33 114.6 16.2 3.5 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.20 EIM90043.1 - 5.6e-09 35.5 0.0 3.2e-08 33.0 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain RRM_1 PF00076.17 EIM90044.1 - 1.7e-15 56.3 0.2 4.4e-15 55.0 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM90044.1 - 2.8e-13 49.6 0.0 3.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90044.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EIM90044.1 - 0.0057 16.3 0.1 0.0078 15.9 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EIM90044.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ureidogly_hydro PF04115.7 EIM90044.1 - 0.044 13.1 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Ureidoglycolate hydrolase TFIID-18kDa PF02269.11 EIM90045.1 - 8.5e-21 73.5 0.1 1.2e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIA PF03153.8 EIM90045.1 - 0.22 11.3 3.1 0.21 11.4 2.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kei1 PF08552.6 EIM90045.1 - 2 8.0 4.4 3 7.4 3.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4211 PF13926.1 EIM90046.1 - 1.3e-21 76.6 0.1 5.2e-21 74.6 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) UNC-79 PF14776.1 EIM90047.1 - 5.7e-06 24.9 0.1 0.00018 20.0 0.0 2.2 2 0 0 2 2 2 2 Cation-channel complex subunit UNC-79 C1_1 PF00130.17 EIM90047.1 - 7.8e-06 25.5 19.9 2.6e-05 23.8 6.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EIM90047.1 - 1.1 8.9 19.2 2.8 7.7 2.5 2.6 2 0 0 2 2 2 0 PHD-finger DPM2 PF07297.7 EIM90048.1 - 3.9e-26 91.1 0.3 4.4e-26 90.9 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EIM90048.1 - 4.2e-05 23.1 0.3 4.4e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 PIG-P TRAPPC9-Trs120 PF08626.6 EIM90049.1 - 3.1e-107 359.4 0.0 2.9e-104 349.5 0.0 2.1 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Kinesin PF00225.18 EIM90050.1 - 1.4e-109 365.8 0.1 5.4e-109 363.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EIM90050.1 - 0.00013 22.1 2.4 0.00013 22.1 1.7 3.7 2 2 1 3 3 3 1 Kinesin-associated microtubule-binding Elf1 PF05129.8 EIM90051.1 - 4.1e-29 100.0 0.5 5e-29 99.8 0.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EIM90051.1 - 0.0015 18.6 0.6 0.0021 18.2 0.4 1.2 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C554 PF13435.1 EIM90051.1 - 0.063 13.3 0.9 0.11 12.5 0.7 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zf-Sec23_Sec24 PF04810.10 EIM90051.1 - 0.099 12.2 0.8 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Nup96 PF12110.3 EIM90051.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Kinesin PF00225.18 EIM90052.1 - 6e-112 373.6 0.2 1.6e-111 372.2 0.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 EIM90052.1 - 0.095 12.1 73.1 0.0086 15.5 29.8 3.6 3 1 1 4 4 4 0 Intermediate filament protein DUF3584 PF12128.3 EIM90052.1 - 0.64 7.2 73.0 0.093 10.0 17.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) PUF PF00806.14 EIM90053.1 - 1.3e-66 216.4 7.9 9.9e-11 40.5 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.6 EIM90053.1 - 0.06 13.1 0.3 6.3 6.6 0.0 3.6 1 1 2 4 4 4 0 CPL (NUC119) domain Sec16 PF12932.2 EIM90054.1 - 3.7e-28 97.8 0.0 5.9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_C PF12931.2 EIM90054.1 - 1.9e-20 73.7 0.1 1.3e-19 71.0 0.0 2.0 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 OST3_OST6 PF04756.8 EIM90055.1 - 3.6e-15 55.8 6.2 5.4e-15 55.3 4.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family DUF998 PF06197.8 EIM90055.1 - 0.00024 20.4 9.7 0.00024 20.4 6.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Thioredoxin PF00085.15 EIM90055.1 - 0.00075 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Innexin PF00876.13 EIM90055.1 - 0.059 12.4 1.9 0.086 11.9 1.3 1.2 1 0 0 1 1 1 0 Innexin TcpE PF12648.2 EIM90055.1 - 0.77 9.9 8.9 1.7 8.8 0.7 2.4 2 0 0 2 2 2 0 TcpE family 7TMR-DISM_7TM PF07695.6 EIM90055.1 - 1.5 8.4 16.9 5.5 6.5 11.7 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling PI3_PI4_kinase PF00454.22 EIM90056.1 - 1e-31 110.1 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Glyco_transf_15 PF01793.11 EIM90057.1 - 7e-137 455.7 5.3 8.7e-137 455.5 3.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EIM90058.1 - 2.2e-139 464.0 3.0 2.6e-139 463.7 2.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Helitron_like_N PF14214.1 EIM90060.1 - 1.3e-14 54.3 0.0 3.3e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIM90061.1 - 3.1e-12 46.1 0.0 2.6e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIM90061.1 - 0.0003 20.4 0.0 7.1 6.1 0.0 3.1 3 0 0 3 3 3 3 AAA domain MFS_1 PF07690.11 EIM90062.1 - 1.1e-22 80.2 39.7 1.5e-22 79.7 27.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF972 PF06156.8 EIM90063.1 - 0.018 15.3 3.5 0.018 15.3 2.4 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EIM90063.1 - 0.028 14.3 11.6 1.1 9.3 1.5 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family CALCOCO1 PF07888.6 EIM90063.1 - 0.19 10.0 19.8 0.0081 14.5 8.4 2.3 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nsp1_C PF05064.8 EIM90063.1 - 0.71 9.5 12.8 0.43 10.2 0.3 3.1 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF1664 PF07889.7 EIM90063.1 - 2.1 8.1 11.3 1.8 8.3 2.5 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ferric_reduct PF01794.14 EIM90064.1 - 2.2e-18 66.5 21.1 6e-18 65.1 9.4 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EIM90064.1 - 4.2e-16 59.2 0.0 4.4e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM90064.1 - 2.8e-12 46.4 0.0 6.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4449 PF14613.1 EIM90065.1 - 1.9e-08 34.4 4.3 1.4e-06 28.3 0.0 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF4449) TRM PF02005.11 EIM90067.1 - 2.2e-122 408.6 0.0 2.9e-122 408.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EIM90067.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TFIIS_C PF01096.13 EIM90067.1 - 0.25 11.0 2.1 4.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Pkinase PF00069.20 EIM90068.1 - 1.2e-68 231.0 0.0 1.8e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90068.1 - 1.3e-47 162.1 0.0 2.1e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.25 EIM90068.1 - 8.2e-15 54.7 0.1 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.1 EIM90068.1 - 3.4e-14 52.6 0.0 7.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EIM90068.1 - 1.1e-13 50.7 0.1 2.2e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EIM90068.1 - 3.9e-06 26.0 0.0 8.4e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF2020 PF09449.5 EIM90068.1 - 0.02 14.5 0.1 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Kdo PF06293.9 EIM90068.1 - 0.078 12.0 0.0 0.21 10.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Daxx PF03344.10 EIM90068.1 - 0.21 10.0 9.8 0.42 9.0 6.8 1.4 1 0 0 1 1 1 0 Daxx Family IGR PF09597.5 EIM90068.1 - 0.23 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 IGR protein motif Nop14 PF04147.7 EIM90068.1 - 0.34 8.7 13.4 0.53 8.1 9.3 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIM90068.1 - 0.47 9.6 8.3 0.81 8.9 5.8 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EIM90068.1 - 1.1 7.2 4.6 1.6 6.7 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EIM90068.1 - 5.6 5.8 8.4 9.6 5.1 5.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Alpha-amylase PF00128.19 EIM90069.1 - 6.2e-29 101.3 0.1 2e-27 96.4 0.0 3.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EIM90069.1 - 4.1e-16 59.2 0.0 7.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIM90069.1 - 1e-08 34.8 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIM90069.1 - 3e-08 33.9 0.0 7.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Histone PF00125.19 EIM90070.1 - 1.6e-21 76.1 0.3 2.4e-21 75.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM90070.1 - 1.3e-06 28.3 0.1 3.2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIM90070.1 - 0.00036 20.7 0.0 0.0006 20.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EIM90070.1 - 0.013 15.9 0.7 0.018 15.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DHHW PF14286.1 EIM90070.1 - 0.068 12.4 2.2 0.081 12.2 1.5 1.0 1 0 0 1 1 1 0 DHHW protein Bt_P21 PF05560.6 EIM90070.1 - 0.07 12.5 0.1 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF3408 PF11888.3 EIM90070.1 - 0.51 10.2 5.8 0.88 9.5 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF2360 PF10152.4 EIM90070.1 - 4.7 7.4 6.1 6.1 7.1 4.1 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Methyltransf_11 PF08241.7 EIM90071.1 - 1.6e-16 60.5 0.0 3.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM90071.1 - 5.2e-09 36.4 0.0 9.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM90071.1 - 1.3e-08 34.7 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90071.1 - 7.8e-07 29.6 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM90071.1 - 6.8e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM90071.1 - 9.6e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90071.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM90071.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MaoC_dehydratas PF01575.14 EIM90072.1 - 2.1e-05 23.8 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Histone PF00125.19 EIM90073.1 - 6.5e-20 71.0 0.6 1e-19 70.4 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIM90073.1 - 8.8e-05 22.4 0.6 0.00024 21.0 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIM90073.1 - 0.05 13.8 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EIM90073.1 - 0.074 13.5 3.8 0.18 12.3 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EIM90073.1 - 0.081 12.3 1.7 0.29 10.5 0.0 2.3 1 1 2 3 3 3 0 Replication protein C N-terminal domain SOBP PF15279.1 EIM90073.1 - 0.57 10.5 5.8 0.68 10.2 4.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3408 PF11888.3 EIM90073.1 - 1.2 9.0 6.2 2.1 8.2 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF913 PF06025.7 EIM90073.1 - 2.1 6.9 6.0 2.5 6.7 3.9 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) PRCC PF10253.4 EIM90074.1 - 6.2e-31 108.4 1.7 6.2e-31 108.4 1.2 2.9 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Nucleoporin_C PF03177.9 EIM90075.1 - 2.9e-43 148.3 0.0 4.2e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIM90075.1 - 5.4e-17 61.6 0.0 7.7e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Zn_clus PF00172.13 EIM90076.1 - 0.47 10.4 11.7 2.5 8.0 1.0 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP PF02037.22 EIM90077.1 - 3e-12 45.7 0.3 7.7e-12 44.4 0.2 1.7 2 0 0 2 2 2 1 SAP domain OTT_1508_deam PF14441.1 EIM90079.1 - 2.6e-17 62.9 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase WD40 PF00400.27 EIM90080.1 - 1.1e-11 44.0 13.1 0.0032 17.2 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EIM90080.1 - 0.0077 14.4 0.7 0.026 12.6 0.2 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 IATP PF04568.7 EIM90081.1 - 2.6e-06 27.3 2.7 2.6e-06 27.3 1.9 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF4662 PF15578.1 EIM90081.1 - 0.0083 15.7 2.1 0.0094 15.5 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4662) Cellulase PF00150.13 EIM90082.1 - 1.6e-11 43.9 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RAP1 PF07218.6 EIM90082.1 - 2.1 6.3 9.4 2.9 5.8 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2367 PF10164.4 EIM90084.1 - 9.6e-08 31.7 2.7 9.6e-08 31.7 1.9 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) WD40 PF00400.27 EIM90085.1 - 2.5e-64 211.0 22.2 1.8e-11 43.4 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIM90085.1 - 4.3e-06 25.1 9.4 0.12 10.5 0.1 4.9 2 2 2 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIM90085.1 - 0.0025 17.3 0.1 0.47 9.8 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain LisH PF08513.6 EIM90085.1 - 0.01 15.5 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 LisH eIF2A PF08662.6 EIM90085.1 - 0.058 13.0 3.9 0.72 9.5 0.1 3.2 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Chromo PF00385.19 EIM90086.1 - 2.1e-12 46.5 3.2 3.9e-12 45.6 2.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.1 EIM90086.1 - 0.26 10.2 0.2 0.35 9.8 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.11 EIM90087.1 - 4e-30 104.7 30.4 4e-30 104.7 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SNF2_N PF00176.18 EIM90088.1 - 5.7e-67 225.6 0.0 8.5e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EIM90088.1 - 8.2e-37 126.8 6.0 1.3e-36 126.2 4.1 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EIM90088.1 - 3.5e-13 49.2 0.0 6.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIM90088.1 - 2.4e-08 33.1 0.0 1e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EIM90088.1 - 0.059 13.1 0.0 0.66 9.7 0.0 2.8 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM90088.1 - 0.13 12.4 0.0 0.76 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain GYF PF02213.11 EIM90089.1 - 6.6e-07 28.8 1.2 1.4e-06 27.8 0.8 1.6 1 0 0 1 1 1 1 GYF domain Oxysterol_BP PF01237.13 EIM90089.1 - 0.31 9.4 3.0 0.45 8.9 2.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein PQ-loop PF04193.9 EIM90090.1 - 2.4e-36 123.0 11.9 1.4e-19 69.4 0.2 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EIM90090.1 - 0.53 10.1 3.2 0.53 10.1 0.3 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CLTH PF10607.4 EIM90091.1 - 9.6e-18 64.2 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIM90091.1 - 0.0067 16.1 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 LisH LRR_6 PF13516.1 EIM90092.1 - 0.0039 17.0 0.2 0.15 12.1 0.0 3.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 EIM90092.1 - 0.021 14.9 2.9 1.9 9.0 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EIM90092.1 - 0.03 13.9 0.2 0.97 9.1 0.0 2.8 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM90092.1 - 0.12 12.4 0.1 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat DUF2665 PF11654.3 EIM90095.1 - 6.3e-16 57.6 0.0 7.6e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) NatB_MDM20 PF09797.4 EIM90096.1 - 4.2e-63 213.2 10.1 5.9e-63 212.7 3.7 2.8 3 1 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 EIM90096.1 - 3.6e-06 27.4 0.1 0.38 11.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM90096.1 - 1.1e-05 25.6 0.4 1.9 9.3 0.0 6.1 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM90096.1 - 1.2e-05 25.5 3.0 0.04 14.2 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM90096.1 - 0.00026 20.5 1.4 0.93 9.1 0.7 3.4 3 0 0 3 3 3 2 TPR repeat Coatomer_E PF04733.9 EIM90096.1 - 0.016 14.4 0.1 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit BTAD PF03704.12 EIM90096.1 - 0.42 10.9 0.0 1.6 9.0 0.0 4.7 5 1 2 7 7 7 0 Bacterial transcriptional activator domain RPA_C PF08784.6 EIM90097.1 - 9.4e-15 54.8 0.2 3.4e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EIM90097.1 - 6.3e-08 32.3 0.1 9.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EIM90097.1 - 0.01 15.6 0.1 0.054 13.3 0.0 2.0 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain Lipase_GDSL_2 PF13472.1 EIM90098.1 - 8.7e-08 32.4 0.2 1.6e-07 31.6 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM90098.1 - 0.00012 22.0 0.0 0.00038 20.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ATG_C PF09333.6 EIM90099.1 - 7.3e-32 109.4 0.1 1.6e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EIM90099.1 - 1.8e-09 37.1 0.0 4.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 EIM90099.1 - 0.00043 19.8 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Ribosomal_L24e PF01246.15 EIM90100.1 - 3.2e-30 103.7 3.9 3.2e-30 103.7 2.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 EIM90100.1 - 0.019 14.5 4.9 0.045 13.4 3.4 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif SH2_2 PF14633.1 EIM90101.1 - 1.1e-66 224.1 0.1 1.1e-66 224.1 0.1 2.2 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EIM90101.1 - 2.1e-29 101.9 0.1 1e-28 99.7 0.1 2.3 1 0 0 1 1 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 EIM90101.1 - 8.8e-29 99.6 0.0 1.8e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EIM90101.1 - 1.6e-25 89.4 0.0 3.8e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EIM90101.1 - 5.5e-18 64.9 34.6 5.5e-18 64.9 24.0 5.7 4 1 2 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EIM90101.1 - 8.5e-13 48.3 0.9 3e-12 46.6 0.6 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EIM90101.1 - 1.5e-07 31.1 0.0 1.6e-05 24.5 0.0 3.4 3 0 0 3 3 3 1 SH2 domain S1 PF00575.18 EIM90101.1 - 0.0045 17.0 1.4 0.011 15.8 1.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 EIM90101.1 - 0.0066 16.3 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4131 PF13567.1 EIM90102.1 - 9.8 5.5 7.6 0.22 10.9 0.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SRP54 PF00448.17 EIM90103.1 - 1e-72 243.7 1.9 1.8e-72 242.9 1.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EIM90103.1 - 1.1e-22 80.2 0.5 1.1e-22 80.2 0.3 4.5 2 2 2 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 EIM90103.1 - 6.2e-15 55.0 5.4 1.3e-14 54.0 3.7 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EIM90103.1 - 3.1e-06 27.1 0.1 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EIM90103.1 - 1e-05 25.0 0.4 2.1e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EIM90103.1 - 0.0015 18.2 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIM90103.1 - 0.0017 17.4 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.18 EIM90103.1 - 0.0087 15.4 0.3 0.049 13.0 0.2 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EIM90103.1 - 0.029 15.2 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM90103.1 - 0.11 12.6 0.2 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2201 PF09967.4 EIM90103.1 - 0.16 11.9 0.8 0.82 9.7 0.1 2.6 2 1 1 3 3 3 0 VWA-like domain (DUF2201) SRPRB PF09439.5 EIM90103.1 - 0.24 10.6 2.7 12 5.0 0.0 2.8 3 1 1 4 4 4 0 Signal recognition particle receptor beta subunit WD40 PF00400.27 EIM90104.1 - 3.5e-20 71.0 14.4 0.0013 18.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat CXCR4_N PF12109.3 EIM90104.1 - 1.6 8.5 5.1 3.1 7.6 3.5 1.5 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Methyltransf_23 PF13489.1 EIM90105.1 - 7.6e-14 51.7 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM90105.1 - 5.5e-10 39.6 0.0 1.3e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90105.1 - 5.1e-08 32.6 0.0 1.2e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90105.1 - 1e-06 29.2 0.0 3.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM90105.1 - 1e-05 25.8 0.0 0.0003 21.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM90105.1 - 6.7e-05 22.8 0.1 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIM90105.1 - 0.00013 21.6 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EIM90105.1 - 0.00062 18.8 0.0 0.0029 16.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.11 EIM90105.1 - 0.0036 15.6 0.0 0.011 14.0 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 EIM90105.1 - 0.0041 16.2 0.0 0.62 9.1 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIM90105.1 - 0.0056 16.0 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EIM90105.1 - 0.0096 15.0 0.0 0.64 9.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EIM90105.1 - 0.016 15.5 0.0 0.052 13.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EIM90105.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RRM_1 PF00076.17 EIM90106.1 - 6.5e-80 262.7 3.8 2.6e-21 75.0 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM90106.1 - 1.5e-55 185.0 0.2 2.3e-15 56.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90106.1 - 5.2e-46 154.3 0.5 2.4e-12 46.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIM90106.1 - 1.4e-26 91.9 3.9 3.2e-26 90.7 2.3 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EIM90106.1 - 0.00013 21.6 1.5 0.055 13.2 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 EIM90106.1 - 0.00056 19.6 0.7 1.6 8.5 0.0 4.3 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EIM90106.1 - 0.0063 16.7 0.6 0.16 12.2 0.0 3.1 4 0 0 4 4 4 1 Cobalamin biosynthesis central region DUF939_C PF11728.3 EIM90106.1 - 0.02 14.6 0.1 0.02 14.6 0.0 2.1 2 0 0 2 2 2 0 DUF939 C-terminal domain OB_RNB PF08206.6 EIM90106.1 - 0.029 13.8 1.2 13 5.3 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF1494 PF07379.6 EIM90106.1 - 0.037 13.9 0.0 0.16 11.8 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1494) YflT PF11181.3 EIM90106.1 - 0.18 12.0 3.9 2.9 8.0 0.4 3.2 3 0 0 3 3 3 0 Heat induced stress protein YflT SCAMP PF04144.8 EIM90107.1 - 2e-43 148.3 6.2 2.3e-43 148.1 4.3 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 EIM90107.1 - 0.37 9.9 2.9 0.61 9.2 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DPBB_1 PF03330.13 EIM90108.1 - 7.2e-08 32.3 1.2 1.4e-07 31.4 0.2 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM90108.1 - 0.00047 19.8 0.3 0.0014 18.3 0.2 1.8 1 0 0 1 1 1 1 Barwin family VKOR PF07884.9 EIM90108.1 - 0.74 9.6 3.6 0.32 10.8 0.7 1.7 2 0 0 2 2 2 0 Vitamin K epoxide reductase family NAD_binding_10 PF13460.1 EIM90109.1 - 3.6e-13 49.9 0.0 2e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIM90109.1 - 2.6e-11 43.4 0.0 4.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90109.1 - 5.1e-05 22.1 0.0 0.00014 20.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIM90109.1 - 0.016 14.1 0.1 3 6.7 0.0 2.9 3 0 0 3 3 3 0 Male sterility protein adh_short PF00106.20 EIM90109.1 - 0.052 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIM90109.1 - 0.079 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EIM90109.1 - 0.15 11.2 0.3 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family ADK PF00406.17 EIM90110.1 - 9e-43 145.7 0.0 1.2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIM90110.1 - 3.3e-12 45.8 0.0 5.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIM90110.1 - 2.1e-05 25.3 0.0 3.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM90110.1 - 0.001 19.4 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM90110.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIM90110.1 - 0.069 12.2 0.2 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Methyltransf_PK PF05891.7 EIM90111.1 - 2e-47 161.3 0.0 3.7e-28 98.3 0.1 3.0 2 2 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EIM90111.1 - 0.0042 17.6 0.0 0.0098 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM90111.1 - 0.016 15.6 0.0 6.8 7.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIM90111.1 - 0.017 15.5 0.0 0.14 12.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM90111.1 - 0.063 13.7 0.0 0.37 11.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Swi3 PF07962.7 EIM90112.1 - 4.8e-25 87.0 0.5 1.4e-24 85.5 0.1 1.9 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Glyco_transf_18 PF15024.1 EIM90113.1 - 1.1e-09 37.2 0.0 1.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 HSA PF07529.8 EIM90114.1 - 3e-18 65.3 2.5 3e-18 65.3 1.7 3.3 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EIM90114.1 - 2.9e-06 27.2 0.3 8.1e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIM90114.1 - 1.9e-05 24.5 0.5 4.7e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain YdfA_immunity PF12127.3 EIM90114.1 - 0.26 10.1 3.4 0.46 9.3 2.4 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial SMI1_KNR4 PF09346.5 EIM90115.1 - 6.3e-28 97.3 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Nucleoplasmin PF03066.10 EIM90115.1 - 0.29 10.6 7.2 0.51 9.8 5.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin CoA_trans PF01144.18 EIM90116.1 - 6.7e-103 342.5 3.0 3.3e-59 199.6 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EIM90116.1 - 0.0031 17.1 0.1 0.0061 16.2 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_35 PF01301.14 EIM90117.1 - 1.7e-83 280.6 0.2 2.3e-83 280.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM90117.1 - 1.8e-43 147.3 3.7 4.4e-22 78.4 0.1 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM90117.1 - 4.2e-37 127.2 0.6 7.1e-37 126.5 0.4 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM90117.1 - 1.2e-13 50.2 0.0 3e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 CoA_trans PF01144.18 EIM90118.1 - 1.6e-104 347.7 1.1 9.3e-66 221.0 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EIM90118.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cofilin_ADF PF00241.15 EIM90119.1 - 6.3e-27 93.9 0.0 2.1e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FYVE PF01363.16 EIM90120.1 - 3.2e-17 62.1 1.2 5.4e-17 61.4 0.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 EIM90120.1 - 0.00031 20.2 0.5 0.00063 19.2 0.3 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain DUF4206 PF13901.1 EIM90120.1 - 0.028 13.9 0.8 0.06 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) FYVE_2 PF02318.11 EIM90120.1 - 0.034 14.0 0.6 0.094 12.6 0.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC5 PF06221.8 EIM90120.1 - 0.08 12.7 6.9 0.047 13.4 3.4 1.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Sec66 PF09802.4 EIM90121.1 - 3.8e-51 173.1 0.0 4.6e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.16 EIM90122.1 - 3.8e-100 335.0 0.0 4.6e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase B56 PF01603.15 EIM90124.1 - 1.1e-170 567.6 5.5 1.4e-170 567.3 3.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Recep_L_domain PF01030.19 EIM90124.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Receptor L domain HSP70 PF00012.15 EIM90125.1 - 1.6e-275 914.7 4.4 1.9e-275 914.5 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM90125.1 - 9.9e-16 57.2 0.0 1.5e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EIM90125.1 - 0.0024 17.0 0.1 0.02 13.9 0.0 2.3 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EIM90125.1 - 0.0028 17.2 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PhoD PF09423.5 EIM90126.1 - 1.7e-130 435.6 1.7 1.9e-130 435.4 1.2 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase DEAD PF00270.24 EIM90127.1 - 6.2e-35 120.1 0.0 1.4e-34 118.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIM90127.1 - 4.2e-22 77.4 0.4 1.1e-21 76.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIM90127.1 - 4e-18 65.0 0.0 8.9e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM90127.1 - 4.5e-05 23.3 0.0 0.00024 20.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM90127.1 - 0.034 14.2 0.2 0.25 11.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIM90127.1 - 0.055 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Fungal_trans PF04082.13 EIM90128.1 - 8.2e-17 60.9 0.1 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM90128.1 - 0.0025 17.6 11.3 0.0064 16.3 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 EIM90128.1 - 0.19 11.5 1.7 0.44 10.4 1.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper SOG2 PF10428.4 EIM90129.1 - 1.7e-60 204.9 9.9 1.7e-60 204.9 6.9 2.6 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.1 EIM90129.1 - 2.2e-11 43.3 2.0 2.7e-06 27.0 0.4 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EIM90129.1 - 4.9e-11 41.9 3.1 2.9e-06 26.7 0.4 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM90129.1 - 3.1e-05 23.3 3.8 3.7 7.9 0.1 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EIM90129.1 - 0.0021 17.9 7.2 2 8.9 0.2 5.2 5 0 0 5 5 5 1 Leucine rich repeat MukB PF04310.7 EIM90129.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal USP7_ICP0_bdg PF12436.3 EIM90130.1 - 1.1e-86 290.1 0.1 2.3e-86 289.1 0.1 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EIM90130.1 - 4.1e-69 232.2 0.5 2e-66 223.4 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EIM90130.1 - 5.7e-55 186.3 0.0 9.4e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM90130.1 - 2.3e-30 106.0 0.0 3.4e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EIM90130.1 - 1.3e-07 31.9 0.0 1.9e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 MATH domain Thioredoxin PF00085.15 EIM90131.1 - 2.9e-25 87.9 0.0 3.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIM90131.1 - 7.6e-09 35.7 0.1 2.3e-07 30.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM90131.1 - 8.3e-07 29.0 0.1 1.5e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIM90131.1 - 1.7e-05 24.3 0.1 1.8e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EIM90131.1 - 0.0011 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM90131.1 - 0.0042 16.6 0.1 0.0058 16.1 0.0 1.3 1 1 0 1 1 1 1 Redoxin DUF713 PF05218.9 EIM90131.1 - 0.0045 16.7 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF713) Thioredoxin_7 PF13899.1 EIM90131.1 - 0.017 15.1 0.1 0.023 14.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like DNA_primase_lrg PF04104.9 EIM90133.1 - 1.2e-82 277.0 0.0 1.7e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ion_trans PF00520.26 EIM90134.1 - 0.00082 18.6 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein DUF4140 PF13600.1 EIM90134.1 - 0.04 14.3 0.7 0.07 13.5 0.5 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RIX1 PF08167.7 EIM90134.1 - 0.1 12.2 0.6 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF3847 PF12958.2 EIM90134.1 - 0.52 10.1 4.7 0.91 9.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DivIC PF04977.10 EIM90134.1 - 0.78 9.2 4.7 1.4 8.4 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1524 PF07510.6 EIM90136.1 - 7.5e-13 48.5 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) FUN14 PF04930.10 EIM90137.1 - 6.3e-19 68.1 0.4 1e-18 67.4 0.3 1.3 1 0 0 1 1 1 1 FUN14 family Nol1_Nop2_Fmu PF01189.12 EIM90138.1 - 9.8e-102 340.1 0.0 1.4e-101 339.6 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EIM90138.1 - 0.00088 18.9 0.1 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EIM90138.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM90138.1 - 0.0025 17.3 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIM90138.1 - 0.02 14.8 0.1 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 EIM90138.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SUR7 PF06687.7 EIM90140.1 - 7.8e-21 74.6 15.9 1.1e-20 74.1 11.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIM90140.1 - 0.0027 17.4 5.7 0.0027 17.4 4.0 2.7 1 1 2 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction Prominin PF05478.6 EIM90140.1 - 0.096 10.2 6.5 0.01 13.4 1.1 1.8 1 1 1 2 2 2 0 Prominin Clc-like PF07062.7 EIM90140.1 - 0.17 11.1 12.3 5.2 6.2 5.0 3.1 2 1 0 2 2 2 0 Clc-like Hexapep PF00132.19 EIM90142.1 - 1.1e-08 34.2 11.7 0.0026 17.1 0.8 4.3 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EIM90142.1 - 2.2e-07 30.4 0.0 3.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.13 EIM90142.1 - 4.4e-07 29.7 2.1 4.4e-07 29.7 1.5 5.1 3 3 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 EIM90142.1 - 0.00017 21.0 12.8 0.003 17.0 4.3 3.5 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EIM90142.1 - 0.00046 20.2 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EIM90142.1 - 0.01 14.4 1.0 0.025 13.1 0.7 1.6 2 0 0 2 2 2 1 L-fucokinase Microvir_lysis PF04517.7 EIM90142.1 - 0.25 11.1 3.7 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus SGT1 PF07093.6 EIM90142.1 - 0.57 8.4 23.3 1 7.6 16.1 1.4 1 0 0 1 1 1 0 SGT1 protein NOA36 PF06524.7 EIM90142.1 - 1.8 7.7 38.5 2.1 7.5 6.4 2.7 3 0 0 3 3 3 0 NOA36 protein SDA1 PF05285.7 EIM90142.1 - 8.9 5.4 46.4 7.9 5.6 10.7 2.4 2 0 0 2 2 2 0 SDA1 Pmp3 PF01679.12 EIM90143.1 - 1.7e-07 30.8 0.2 3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Aminotran_5 PF00266.14 EIM90144.1 - 1.4e-12 47.0 0.0 1.8e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 EIM90145.1 - 2.6e-15 56.3 0.0 1.3e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM90145.1 - 2.1e-05 23.5 0.0 0.00089 18.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIM90145.1 - 4.3e-05 23.8 0.0 0.001 19.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM90145.1 - 0.00031 20.6 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIM90145.1 - 0.002 17.0 0.1 0.018 13.8 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 EIM90145.1 - 0.0082 14.6 0.0 0.16 10.4 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein XdhC_C PF13478.1 EIM90145.1 - 0.031 14.5 0.3 0.7 10.1 0.0 2.5 3 0 0 3 3 3 0 XdhC Rossmann domain Trp_halogenase PF04820.9 EIM90145.1 - 0.097 11.2 0.1 5.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EIM90145.1 - 0.098 12.4 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM90145.1 - 0.1 12.4 0.1 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIM90145.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM90145.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EIM90145.1 - 0.17 11.3 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AT_hook PF02178.14 EIM90146.1 - 0.014 15.0 44.1 0.37 10.6 7.3 3.7 3 0 0 3 3 3 0 AT hook motif PRKCSH PF07915.8 EIM90147.1 - 3.6e-12 46.9 1.3 5.7e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EIM90147.1 - 1.9e-05 24.2 0.0 0.00017 21.0 0.0 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase PF00069.20 EIM90148.1 - 1.7e-54 184.7 0.0 9.9e-54 182.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90148.1 - 3.6e-26 91.8 0.0 5.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90148.1 - 0.0094 15.7 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM90148.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.20 EIM90150.1 - 8.9e-17 61.5 0.2 1.6e-16 60.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM90150.1 - 2.7e-05 23.9 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIM90150.1 - 0.0033 17.4 0.0 0.0094 15.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EIM90150.1 - 0.0053 15.9 0.1 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_hydro_31 PF01055.21 EIM90150.1 - 0.083 11.7 0.0 0.14 10.9 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 31 Ten1 PF12658.2 EIM90150.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Glyco_tran_WecB PF03808.8 EIM90150.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DEAD PF00270.24 EIM90151.1 - 1.3e-41 141.8 0.0 2.7e-40 137.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM90151.1 - 1.7e-23 82.2 0.1 4e-23 81.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM90151.1 - 2.8e-05 23.0 0.0 4.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIM90151.1 - 0.033 14.0 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_16 PF10294.4 EIM90153.1 - 4.4e-17 62.0 0.0 2e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EIM90153.1 - 2.6e-05 24.0 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90153.1 - 0.00044 20.8 0.0 0.00086 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAM_MT PF04445.8 EIM90153.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MTS PF05175.9 EIM90153.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 EIM90153.1 - 0.16 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB RhoGEF PF00621.15 EIM90154.1 - 2.5e-18 66.5 0.0 2.5e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Asn_synthase PF00733.16 EIM90155.1 - 5e-73 245.7 0.0 7.4e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIM90155.1 - 4.7e-36 123.2 0.0 8e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIM90155.1 - 5.7e-29 100.7 0.0 2.3e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EIM90155.1 - 0.003 16.3 0.0 0.011 14.4 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EIM90155.1 - 0.029 13.2 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase QueC PF06508.8 EIM90155.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Aldo_ket_red PF00248.16 EIM90156.1 - 6e-46 156.5 0.0 6.8e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTT_1508_deam PF14441.1 EIM90157.1 - 1.3e-07 31.5 0.1 4.1e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase Ribosomal_L32p PF01783.18 EIM90157.1 - 0.04 14.1 0.1 0.17 12.0 0.1 2.1 1 0 0 1 1 1 0 Ribosomal L32p protein family Syntaxin PF00804.20 EIM90158.1 - 1e-14 54.5 0.9 1e-14 54.5 0.6 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EIM90158.1 - 1.5e-13 50.1 4.3 5.5e-13 48.4 3.0 2.0 1 0 0 1 1 1 1 SNARE domain FUSC PF04632.7 EIM90158.1 - 0.0039 15.6 3.1 0.0039 15.6 2.2 1.9 1 1 1 2 2 2 1 Fusaric acid resistance protein family Syntaxin_2 PF14523.1 EIM90158.1 - 0.008 16.1 4.5 0.008 16.1 3.1 2.1 2 0 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 EIM90158.1 - 0.022 14.3 4.6 1.2 8.5 1.0 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4454 PF14628.1 EIM90158.1 - 0.043 13.4 0.1 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) ACC_epsilon PF13822.1 EIM90158.1 - 0.049 13.9 0.1 0.049 13.9 0.0 2.5 3 0 0 3 3 1 0 Acyl-CoA carboxylase epsilon subunit Synaptobrevin PF00957.16 EIM90158.1 - 0.065 12.8 7.8 0.18 11.4 0.4 2.5 2 0 0 2 2 2 0 Synaptobrevin Med28 PF11594.3 EIM90158.1 - 0.068 13.4 2.5 1.4 9.2 0.1 2.8 2 1 1 3 3 3 0 Mediator complex subunit 28 DUF3829 PF12889.2 EIM90158.1 - 0.13 11.4 4.4 1 8.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF3040 PF11239.3 EIM90158.1 - 0.14 12.2 0.2 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Allexi_40kDa PF05549.6 EIM90158.1 - 0.2 10.8 3.5 0.22 10.7 0.3 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein BatA PF07584.6 EIM90158.1 - 0.24 11.6 1.8 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4231 PF14015.1 EIM90158.1 - 0.3 11.0 1.9 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) LOH1CR12 PF10158.4 EIM90158.1 - 0.4 10.4 6.2 0.98 9.2 0.1 2.7 3 1 0 3 3 2 0 Tumour suppressor protein BLOC1_2 PF10046.4 EIM90158.1 - 0.52 10.4 4.0 14 5.8 0.2 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hrs_helical PF12210.3 EIM90158.1 - 0.58 10.4 6.6 14 6.0 0.2 3.5 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TBPIP PF07106.8 EIM90158.1 - 0.74 9.3 7.1 8.1 5.9 0.4 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 EIM90158.1 - 2.3 8.0 6.0 6.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.7 EIM90158.1 - 4.1 7.8 11.1 0.66 10.3 1.1 3.4 2 1 2 4 4 4 0 SlyX CDP-OH_P_transf PF01066.16 EIM90159.1 - 4.6e-19 68.6 5.7 4.6e-19 68.6 3.9 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ICL PF00463.16 EIM90160.1 - 7.5e-187 621.6 0.0 8.5e-187 621.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DNA_methylase PF00145.12 EIM90161.1 - 8.6e-39 133.5 0.0 6.3e-37 127.4 0.0 3.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 EIM90161.1 - 7.9e-13 48.3 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 EIM90161.1 - 6.4e-08 32.3 0.0 7.2e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 BAH domain Cons_hypoth95 PF03602.10 EIM90161.1 - 0.00064 19.1 0.0 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EIM90161.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIM90161.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.2 EIM90161.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.24 EIM90162.1 - 5.6e-36 123.6 0.0 1.2e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM90162.1 - 3.2e-06 27.2 1.3 0.0012 18.8 0.1 4.7 3 2 2 5 5 5 1 AAA ATPase domain AAA_5 PF07728.9 EIM90162.1 - 0.00013 21.6 0.0 0.00057 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIM90162.1 - 0.00046 20.9 1.5 0.0013 19.5 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIM90162.1 - 0.00053 20.1 0.0 0.013 15.6 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM90162.1 - 0.0012 18.6 0.1 0.0036 17.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EIM90162.1 - 0.0035 17.3 0.2 0.029 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EIM90162.1 - 0.0048 16.5 0.3 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIM90162.1 - 0.0055 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIM90162.1 - 0.0057 16.5 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIM90162.1 - 0.0063 16.8 0.4 0.11 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIM90162.1 - 0.01 15.2 0.3 0.031 13.7 0.0 2.0 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EIM90162.1 - 0.024 14.5 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIM90162.1 - 0.029 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIM90162.1 - 0.074 12.4 0.1 11 5.3 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain Mg_chelatase PF01078.16 EIM90162.1 - 0.098 11.8 0.2 0.23 10.5 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EIM90162.1 - 0.1 11.5 0.0 0.23 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EIM90162.1 - 0.11 11.9 1.0 2.7 7.3 0.1 2.9 2 1 1 3 3 3 0 AAA domain TIP49 PF06068.8 EIM90162.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EIM90162.1 - 0.2 11.8 0.0 0.58 10.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CDP-OH_P_transf PF01066.16 EIM90163.1 - 9.8e-12 45.0 3.2 9.8e-12 45.0 2.2 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAP2 PF01569.16 EIM90164.1 - 3.6e-11 42.8 2.4 3.6e-11 42.8 1.7 3.2 3 1 0 3 3 3 1 PAP2 superfamily Ring_hydroxyl_A PF00848.14 EIM90165.1 - 0.065 12.8 3.6 0.092 12.3 2.5 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) FAM70 PF14967.1 EIM90166.1 - 0.25 10.5 11.2 0.55 9.3 7.7 1.6 1 0 0 1 1 1 0 FAM70 protein HEAT PF02985.17 EIM90167.1 - 6.9e-13 47.5 16.6 6.6e-05 22.6 0.1 7.9 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EIM90167.1 - 1.3e-09 38.2 12.2 2.1e-05 24.6 0.1 6.1 4 2 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EIM90167.1 - 0.28 11.7 12.9 0.73 10.3 0.2 5.2 4 1 2 6 6 6 0 HEAT-like repeat Aminotran_1_2 PF00155.16 EIM90168.1 - 2.4e-82 276.7 0.0 2.7e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.11 EIM90169.1 - 1e-08 34.8 9.9 1.7e-08 34.1 6.9 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 EIM90169.1 - 1.4 8.8 9.8 1.9 8.4 6.5 1.5 1 1 0 1 1 1 0 IBR domain DUF35_N PF12172.3 EIM90169.1 - 4.6 7.2 6.7 7.6 6.5 0.4 2.4 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RING_4 PF14570.1 EIM90169.1 - 5.3 6.7 8.4 0.88 9.2 3.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SNARE PF05739.14 EIM90170.1 - 1.2e-13 50.5 1.9 3.9e-13 48.8 1.3 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EIM90170.1 - 7.2e-12 45.3 10.0 1e-11 44.8 2.6 2.4 2 0 0 2 2 2 1 Syntaxin Tweety PF04906.8 EIM90170.1 - 0.028 12.8 2.2 0.21 9.9 0.1 2.2 2 0 0 2 2 2 0 Tweety Spectrin PF00435.16 EIM90170.1 - 0.038 14.2 5.1 0.41 10.9 0.0 2.9 3 0 0 3 3 3 0 Spectrin repeat VitD-bind_III PF09164.5 EIM90170.1 - 0.089 12.4 0.1 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Syntaxin_2 PF14523.1 EIM90170.1 - 0.19 11.7 12.4 0.12 12.4 6.0 2.3 2 1 0 2 2 2 0 Syntaxin-like protein WXG100 PF06013.7 EIM90170.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4094 PF13334.1 EIM90170.1 - 0.29 11.5 3.1 1.4 9.3 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Wzy_C PF04932.10 EIM90170.1 - 1.5 8.5 3.7 0.48 10.2 0.4 1.8 2 0 0 2 2 2 0 O-Antigen ligase Lyase_1 PF00206.15 EIM90171.1 - 9e-96 320.7 0.0 1.3e-95 320.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EIM90171.1 - 5.1e-28 96.9 0.1 1.1e-27 95.8 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Phage_term_smal PF05944.7 EIM90171.1 - 0.11 12.1 0.1 1.5 8.5 0.0 2.3 2 1 1 3 3 3 0 Phage small terminase subunit Peptidase_M24 PF00557.19 EIM90172.1 - 8.5e-39 133.2 0.0 1.1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 2OG-FeII_Oxy_2 PF13532.1 EIM90173.1 - 3.1e-23 82.6 0.0 3.7e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIM90173.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_M13_N PF05649.8 EIM90174.1 - 3.1e-89 299.7 0.0 4.5e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EIM90174.1 - 2e-53 180.6 0.0 3.7e-53 179.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 SSP160 PF06933.6 EIM90174.1 - 2 6.3 11.5 2.7 5.8 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-Mss51 PF13824.1 EIM90175.1 - 4e-23 81.0 10.1 6.9e-23 80.2 7.0 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 EIM90175.1 - 0.023 14.9 6.4 0.047 13.9 4.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF1610 PF07754.6 EIM90175.1 - 0.21 11.7 0.2 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CDC45 PF02724.9 EIM90176.1 - 3.9e-174 580.1 0.0 4.4e-174 579.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein VID27 PF08553.5 EIM90176.1 - 1.3 7.1 3.1 1.9 6.6 2.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Scramblase PF03803.10 EIM90177.1 - 2e-56 190.5 0.0 6.9e-56 188.7 0.0 1.7 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.22 EIM90178.1 - 6.7e-39 133.2 1.5 3.9e-38 130.7 1.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIM90178.1 - 5.6e-24 84.1 0.3 1.4e-23 82.8 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIM90178.1 - 3.5e-09 36.6 0.7 8.3e-05 22.6 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM90178.1 - 4.7e-07 29.7 0.1 1.2e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EIM90178.1 - 8.5e-05 22.1 0.0 0.00022 20.7 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 EIM90178.1 - 0.00053 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIM90178.1 - 0.006 17.0 0.1 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIM90178.1 - 0.0079 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EIM90178.1 - 0.016 14.0 6.3 0.025 13.3 3.4 1.9 1 1 1 2 2 2 0 ArgK protein PduV-EutP PF10662.4 EIM90178.1 - 0.024 14.1 0.7 5 6.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phosphoesterase PF04185.9 EIM90179.1 - 4.2e-27 95.3 2.2 7.7e-27 94.4 1.5 1.4 1 1 0 1 1 1 1 Phosphoesterase family Mito_carr PF00153.22 EIM90180.1 - 1.3e-08 34.4 0.0 0.00046 19.8 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein CPT PF07931.7 EIM90182.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein BCMA-Tall_bind PF09257.5 EIM90182.1 - 0.058 13.3 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 BCMA, TALL-1 binding TrkA_C PF02080.16 EIM90183.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain 2OG-FeII_Oxy_2 PF13532.1 EIM90184.1 - 2.5e-10 40.5 0.0 6.4e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VCBS PF13517.1 EIM90186.1 - 0.037 14.3 0.8 0.047 14.0 0.6 1.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WD40 PF00400.27 EIM90187.1 - 2.6e-47 157.0 16.8 1.4e-13 50.1 0.6 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM90187.1 - 1.4e-06 27.3 1.9 0.0032 16.2 0.2 4.0 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 EIM90187.1 - 5.5e-05 22.4 0.2 0.29 10.2 0.0 2.7 3 0 0 3 3 3 2 TUP1-like enhancer of split eIF2A PF08662.6 EIM90187.1 - 0.0013 18.5 1.7 6.1 6.5 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIM90187.1 - 0.0061 14.7 5.1 2.1 6.3 0.0 4.0 1 1 1 4 4 4 3 Nucleoporin Nup120/160 PAN_3 PF08277.7 EIM90187.1 - 0.013 15.1 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 0 PAN-like domain DUF3312 PF11768.3 EIM90187.1 - 0.044 12.0 0.0 0.066 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Glu_synthase PF01645.12 EIM90188.1 - 4.5e-158 525.9 0.0 7.5e-158 525.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EIM90188.1 - 3.7e-138 460.1 0.0 5e-138 459.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EIM90188.1 - 4.6e-116 387.0 0.0 7e-116 386.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EIM90188.1 - 3e-68 228.7 3.0 3e-68 228.7 2.1 1.6 2 0 0 2 2 1 1 GXGXG motif Fer4_20 PF14691.1 EIM90188.1 - 2.9e-23 81.5 0.1 6.8e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EIM90188.1 - 2.2e-18 66.8 0.0 5.7e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM90188.1 - 3.1e-12 47.0 0.0 9.7e-05 22.5 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM90188.1 - 1.3e-09 38.2 0.1 6.1e-06 26.5 0.0 4.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM90188.1 - 2.1e-09 37.2 0.0 8.6e-09 35.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM90188.1 - 3.2e-06 26.2 3.2 6.8e-05 21.9 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIM90188.1 - 9.1e-06 25.0 0.1 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIM90188.1 - 1.3e-05 23.8 1.0 2.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIM90188.1 - 6e-05 22.0 0.1 0.0022 16.9 0.0 2.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EIM90188.1 - 9.2e-05 21.6 0.7 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EIM90188.1 - 0.00044 20.4 1.0 0.093 12.9 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIM90188.1 - 0.0028 16.7 0.0 0.0069 15.5 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase DJ-1_PfpI PF01965.19 EIM90188.1 - 0.0032 16.9 0.1 3.2 7.2 0.0 2.5 1 1 0 2 2 2 2 DJ-1/PfpI family FAD_binding_3 PF01494.14 EIM90188.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.13 EIM90188.1 - 0.0065 15.3 2.2 0.03 13.1 0.6 2.5 3 0 0 3 3 3 1 FMN-dependent dehydrogenase FMO-like PF00743.14 EIM90188.1 - 0.013 13.6 0.1 0.42 8.7 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EIM90188.1 - 0.019 14.7 0.0 0.065 13.0 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 EIM90188.1 - 0.026 14.3 1.3 5.5 6.7 0.1 3.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM90188.1 - 0.035 13.6 0.0 0.58 9.7 0.0 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EIM90188.1 - 0.04 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EIM90188.1 - 0.043 12.9 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIM90188.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIM90188.1 - 0.082 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GATase_6 PF13522.1 EIM90188.1 - 0.086 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain UDPG_MGDP_dh_N PF03721.9 EIM90188.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EIM90188.1 - 0.32 9.7 1.4 1.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Acetyltransf_13 PF13880.1 EIM90189.1 - 1.6e-13 50.1 0.0 3.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EIM90189.1 - 1e-08 34.5 0.4 1.8e-08 33.7 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EIM90189.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EIM90189.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF605 PF04652.11 EIM90189.1 - 6.7 6.0 22.1 0.45 9.8 9.5 2.0 2 0 0 2 2 2 0 Vta1 like MFS_1 PF07690.11 EIM90190.1 - 8e-20 70.8 23.9 8e-20 70.8 16.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EIM90190.1 - 9.5e-09 34.8 3.6 2.4e-08 33.5 2.5 1.7 1 0 0 1 1 1 1 Nodulin-like Far-17a_AIG1 PF04750.9 EIM90191.1 - 1.1e-36 125.9 4.8 1.2e-36 125.7 3.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein MFS_1 PF07690.11 EIM90192.1 - 3.3e-25 88.5 29.7 3.3e-25 88.5 20.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EIM90194.1 - 4e-73 246.2 0.0 5.4e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM90194.1 - 0.0096 16.8 0.0 0.024 15.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.27 EIM90195.1 - 9.2e-25 84.0 2.0 1.4e-05 24.0 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EIM90195.1 - 1.6e-21 74.2 2.1 4.9e-06 25.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EIM90195.1 - 3e-20 72.0 0.0 1.1e-08 35.0 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIM90195.1 - 2.6e-17 61.2 0.2 0.00051 19.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIM90195.1 - 1.2e-16 60.0 3.3 2.5e-07 30.1 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_2 PF09068.6 EIM90195.1 - 0.029 14.4 0.0 11 6.1 0.0 3.1 2 2 2 4 4 4 0 EF hand XS PF03468.9 EIM90195.1 - 0.092 12.6 0.2 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 XS domain HAD_2 PF13419.1 EIM90196.1 - 4.6e-18 66.0 0.0 1.8e-14 54.3 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM90196.1 - 0.0049 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EIM90196.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase AP_endonuc_2 PF01261.19 EIM90196.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel QCR10 PF09796.4 EIM90197.1 - 8.7e-21 73.3 0.1 1e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DNA_pol_lambd_f PF10391.4 EIM90197.1 - 0.47 10.0 2.1 0.68 9.5 0.2 2.1 1 1 1 2 2 2 0 Fingers domain of DNA polymerase lambda Nop16 PF09420.5 EIM90198.1 - 3.2e-35 121.6 1.6 5.6e-35 120.8 1.1 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 FAM177 PF14774.1 EIM90198.1 - 0.0044 16.9 1.4 0.0078 16.1 1.0 1.4 1 0 0 1 1 1 1 FAM177 family Ribosomal_L36e PF01158.13 EIM90198.1 - 0.0079 16.1 0.1 0.027 14.4 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L36e Zn_clus PF00172.13 EIM90199.1 - 0.02 14.7 7.0 0.039 13.8 4.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_Tnp_IS1595 PF12760.2 EIM90200.1 - 0.014 15.1 2.6 0.052 13.3 1.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF3716 PF12511.3 EIM90200.1 - 0.083 12.5 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Rubredoxin PF00301.15 EIM90200.1 - 0.13 12.1 3.4 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin FYVE_2 PF02318.11 EIM90200.1 - 0.34 10.8 3.0 6.2 6.7 0.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Nudix_N_2 PF14803.1 EIM90200.1 - 2.4 7.9 7.8 0.29 10.8 1.6 2.1 2 0 0 2 2 2 0 Nudix N-terminal zf-Sec23_Sec24 PF04810.10 EIM90200.1 - 3.9 7.1 7.0 0.75 9.4 0.7 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Ras PF00071.17 EIM90201.1 - 2.4e-65 218.8 1.3 3.1e-65 218.5 0.9 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM90201.1 - 8.1e-22 77.9 0.4 5.2e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM90201.1 - 2.6e-17 62.6 0.3 3.2e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM90201.1 - 4.5e-07 29.2 0.1 5.8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM90201.1 - 1.1e-06 28.1 0.3 2.4e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIM90201.1 - 9.6e-06 24.9 0.1 1.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIM90201.1 - 3.1e-05 23.8 0.8 4.5e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM90201.1 - 4.1e-05 22.8 0.4 0.053 12.6 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM90201.1 - 0.00014 21.9 1.6 0.002 18.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIM90201.1 - 0.0015 18.0 0.6 0.083 12.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EIM90201.1 - 0.0033 17.6 1.8 0.34 11.1 0.0 3.1 2 2 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EIM90201.1 - 0.0059 15.8 0.1 0.032 13.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EIM90201.1 - 0.029 14.6 0.5 0.18 12.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EIM90201.1 - 0.029 14.3 3.8 0.068 13.1 0.0 2.7 1 1 1 3 3 3 0 AAA ATPase domain AAA_5 PF07728.9 EIM90201.1 - 0.031 14.0 0.7 0.054 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIM90201.1 - 0.033 14.0 0.2 0.19 11.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EIM90201.1 - 0.069 12.1 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EIM90201.1 - 0.088 12.2 0.1 1.1 8.7 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EIM90201.1 - 0.19 11.9 2.4 1.2 9.3 0.1 2.8 2 1 0 2 2 2 0 RNA helicase Asp PF00026.18 EIM90202.1 - 7.4e-43 146.9 3.3 9.6e-43 146.6 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM90202.1 - 0.014 15.8 1.0 0.45 11.0 0.2 2.8 2 1 0 2 2 2 0 Aspartyl protease Piwi PF02171.12 EIM90203.1 - 8.2e-74 248.2 0.0 1.1e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIM90203.1 - 0.031 13.5 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 PAZ domain WD40 PF00400.27 EIM90204.1 - 4.3e-20 70.7 17.2 2.8e-09 36.5 0.4 6.5 6 2 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIM90204.1 - 0.068 11.9 0.4 2.3 6.8 0.1 2.6 2 1 0 3 3 3 0 Nup133 N terminal like NMO PF03060.10 EIM90205.1 - 7.9e-72 242.1 0.9 9.5e-72 241.9 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIM90205.1 - 1.2e-06 27.6 0.0 0.028 13.3 0.0 2.3 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIM90205.1 - 0.0095 14.8 1.9 0.017 14.0 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.12 EIM90206.1 - 4.1e-78 262.5 0.0 5.1e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.13 EIM90207.1 - 2.9e-48 164.0 0.0 3.7e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 EIM90207.1 - 0.013 15.3 15.0 0.019 14.8 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.4 EIM90207.1 - 0.73 9.9 24.7 1.6 8.7 17.1 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.5 EIM90207.1 - 3 6.8 33.6 1.4 7.8 21.6 1.6 2 0 0 2 2 2 0 BUD22 DUF2457 PF10446.4 EIM90207.1 - 4.5 5.8 32.6 6.6 5.3 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 EIM90209.1 - 1.4e-63 214.4 0.0 1.7e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90209.1 - 8.6e-30 103.6 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM90209.1 - 0.00068 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cytochrom_B561 PF03188.11 EIM90210.1 - 1.4e-09 37.8 9.9 1.4e-09 37.8 6.9 2.3 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF202 PF02656.10 EIM90210.1 - 4.5 7.5 12.4 0.77 10.0 1.3 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Sec7 PF01369.15 EIM90211.1 - 2.5e-60 203.4 0.0 4.2e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIM90211.1 - 2.5e-18 66.0 7.0 4.8e-08 32.6 0.0 4.4 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIM90211.1 - 0.019 14.4 2.8 5.4 6.6 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) DUF2232 PF09991.4 EIM90211.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Proteasome PF00227.21 EIM90212.1 - 2e-59 200.0 0.0 2.8e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIM90212.1 - 1.2e-14 53.2 1.7 1.2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MAT1 PF06391.8 EIM90213.1 - 1.1e-42 145.9 13.3 1.4e-42 145.5 9.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EIM90213.1 - 0.0073 16.0 9.6 0.021 14.5 6.8 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIM90213.1 - 0.047 13.3 10.9 0.15 11.7 7.7 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 EIM90213.1 - 0.12 12.3 2.2 10 6.1 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 EIM90213.1 - 0.16 11.6 9.9 0.44 10.2 6.8 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIM90213.1 - 6.3 6.4 11.1 14 5.3 3.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LigB PF02900.13 EIM90214.1 - 6.8e-47 159.7 0.0 8.9e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Epimerase PF01370.16 EIM90215.1 - 1.1e-06 28.2 0.0 3.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1593 PF07632.6 EIM90215.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) NAD_binding_2 PF03446.10 EIM90216.1 - 5.9e-35 120.5 0.0 8.7e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIM90216.1 - 1.6e-27 96.0 0.0 2.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIM90216.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SRP54 PF00448.17 EIM90217.1 - 9.5e-45 152.4 0.1 8.2e-44 149.3 0.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EIM90217.1 - 3.1e-44 151.4 0.0 4.6e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EIM90217.1 - 1.3e-08 34.8 0.0 5.2e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EIM90217.1 - 2.3e-06 27.1 0.0 5.8e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EIM90217.1 - 7.3e-05 21.6 0.1 0.00017 20.4 0.1 1.5 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EIM90217.1 - 0.0039 16.9 0.0 0.0099 15.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIM90217.1 - 0.0082 16.2 0.0 0.066 13.3 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.1 EIM90217.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM90217.1 - 0.055 13.4 0.1 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Fer4_NifH PF00142.13 EIM90217.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2277 PF10041.4 EIM90217.1 - 0.13 12.1 0.5 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) ArsA_ATPase PF02374.10 EIM90217.1 - 0.16 10.9 0.5 1.9 7.4 0.0 2.2 1 1 0 2 2 2 0 Anion-transporting ATPase Cyclin_N PF00134.18 EIM90218.1 - 1.7e-09 37.3 0.0 4.4e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain SOR_SNZ PF01680.12 EIM90220.1 - 6.5e-114 378.6 4.2 9.4e-114 378.1 2.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EIM90220.1 - 3.2e-11 42.7 1.6 2.2e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EIM90220.1 - 0.00014 20.8 1.2 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EIM90220.1 - 0.0008 18.4 0.3 0.082 11.8 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EIM90220.1 - 0.004 16.4 0.9 0.21 10.8 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EIM90220.1 - 0.011 14.7 0.0 0.04 12.9 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.10 EIM90220.1 - 0.014 14.5 0.1 0.014 14.5 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase FMN_dh PF01070.13 EIM90220.1 - 0.033 13.0 0.3 0.066 12.0 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PEP_mutase PF13714.1 EIM90220.1 - 0.043 13.0 0.6 0.14 11.3 0.2 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Img2 PF05046.9 EIM90221.1 - 4.5e-15 55.6 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) BTB PF00651.26 EIM90223.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DHO_dh PF01180.16 EIM90224.1 - 2.9e-89 298.9 0.0 3.9e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EIM90224.1 - 0.016 14.0 0.1 0.045 12.6 0.1 1.7 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Aldo_ket_red PF00248.16 EIM90225.1 - 1.4e-48 165.1 0.0 1.7e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Dickkopf_N PF04706.7 EIM90226.1 - 0.0011 19.0 5.6 0.0013 18.8 3.9 1.1 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Toxin_23 PF08093.6 EIM90226.1 - 0.007 16.2 8.0 0.0092 15.8 5.6 1.3 1 0 0 1 1 1 1 Magi 5 toxic peptide family Conotoxin PF02950.12 EIM90226.1 - 0.0077 17.0 7.0 0.0077 17.0 4.8 1.6 1 1 1 2 2 2 1 Conotoxin Tad PF13400.1 EIM90226.1 - 0.033 14.2 0.6 0.058 13.4 0.4 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Toxin_19 PF08088.7 EIM90226.1 - 0.036 13.9 6.8 0.044 13.7 4.7 1.1 1 0 0 1 1 1 0 Conotoxin I-superfamily Toxin_12 PF07740.7 EIM90226.1 - 0.036 14.5 5.1 0.057 13.9 3.5 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin UPF0506 PF11703.3 EIM90226.1 - 0.11 12.4 5.9 0.16 11.9 4.1 1.3 1 0 0 1 1 1 0 UPF0506 NIP_1 PF08995.5 EIM90226.1 - 0.15 12.2 2.8 0.15 12.2 1.9 1.2 1 0 0 1 1 1 0 Necrosis inducing protein-1 Transferase PF02458.10 EIM90227.1 - 5.5e-35 120.6 0.0 5.2e-13 48.2 0.0 3.1 3 0 0 3 3 3 3 Transferase family Condensation PF00668.15 EIM90227.1 - 0.16 10.7 0.0 0.35 9.6 0.0 1.5 2 0 0 2 2 2 0 Condensation domain Peptidase_C78 PF07910.8 EIM90228.1 - 1.1e-48 165.2 0.0 2.1e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 CobW_C PF07683.9 EIM90229.1 - 0.019 14.6 0.4 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain TMF_DNA_bd PF12329.3 EIM90229.1 - 0.02 14.6 0.1 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Arena_RNA_pol PF06317.6 EIM90229.1 - 0.052 10.1 0.0 0.062 9.8 0.0 1.1 1 0 0 1 1 1 0 Arenavirus RNA polymerase Lactamase_B PF00753.22 EIM90231.1 - 4.5e-26 91.7 1.8 6.8e-26 91.1 1.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM90231.1 - 0.00053 19.5 0.3 0.00066 19.2 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Got1 PF04178.7 EIM90232.1 - 1.4e-25 89.7 24.3 1.8e-25 89.3 16.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family PPTA PF01239.17 EIM90234.1 - 3.7e-49 162.1 6.9 2e-09 36.3 0.0 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.1 EIM90235.1 - 5.2e-10 39.0 14.3 0.64 10.8 0.0 11.1 11 2 2 13 13 11 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIM90235.1 - 4.3e-06 26.2 9.4 2.5 7.7 0.1 6.7 7 0 0 7 7 7 3 TPR repeat TPR_16 PF13432.1 EIM90235.1 - 1.6e-05 25.4 17.4 0.77 10.5 0.0 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM90235.1 - 2.4e-05 24.1 13.2 0.058 13.3 0.1 7.2 7 2 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM90235.1 - 5e-05 23.5 3.6 4.1 7.8 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 EIM90235.1 - 0.00012 21.8 6.7 0.0057 16.4 0.4 4.7 3 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EIM90235.1 - 0.00016 21.3 16.6 0.08 12.8 0.2 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM90235.1 - 0.0016 18.0 1.0 18 5.4 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EIM90235.1 - 0.002 17.0 6.6 0.09 11.6 0.0 4.3 3 2 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 EIM90235.1 - 0.0037 16.9 2.3 47 4.1 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIM90235.1 - 0.0094 15.7 10.4 2.2 8.0 0.3 5.7 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 HAT PF02184.11 EIM90235.1 - 0.23 11.2 7.4 2.8 7.7 0.0 5.7 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DALR_1 PF05746.10 EIM90235.1 - 0.25 11.3 2.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 DALR anticodon binding domain Ribosomal_L30_N PF08079.7 EIM90236.1 - 3.3e-25 87.9 16.0 3.3e-25 87.9 11.1 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EIM90236.1 - 5e-19 67.6 1.5 1.1e-18 66.5 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e tRNA-synt_1b PF00579.20 EIM90238.1 - 8.1e-20 71.1 0.0 2e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) V_ATPase_I PF01496.14 EIM90239.1 - 4.8e-288 957.2 0.0 5.5e-288 957.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Clusterin PF01093.12 EIM90239.1 - 0.016 14.0 0.4 0.025 13.4 0.3 1.2 1 0 0 1 1 1 0 Clusterin Wzz PF02706.10 EIM90239.1 - 0.15 11.8 0.1 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Chain length determinant protein Adeno_GP19K PF04881.8 EIM90239.1 - 0.23 11.1 3.0 0.38 10.4 0.4 2.3 2 0 0 2 2 2 0 Adenovirus GP19K SlyX PF04102.7 EIM90239.1 - 0.32 11.3 1.4 1.2 9.5 0.2 2.4 3 0 0 3 3 3 0 SlyX Vpu PF00558.14 EIM90239.1 - 4 7.0 6.7 0.84 9.2 0.1 2.9 2 0 0 2 2 2 0 Vpu protein ABC_tran PF00005.22 EIM90240.1 - 2.8e-43 147.4 0.0 8.3e-21 74.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM90240.1 - 1.3e-14 54.8 4.8 0.015 15.2 0.2 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EIM90240.1 - 2.4e-12 46.5 0.6 0.0074 15.5 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIM90240.1 - 2e-08 33.6 0.2 0.0066 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 EIM90240.1 - 3.8e-08 33.5 9.7 0.0022 18.2 0.1 3.9 2 1 1 3 3 2 2 HEAT repeats AAA_17 PF13207.1 EIM90240.1 - 2.1e-07 31.7 0.1 0.0023 18.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EIM90240.1 - 2.3e-06 28.0 0.1 0.061 13.8 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EIM90240.1 - 5e-06 26.8 0.5 0.0034 17.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM90240.1 - 5.4e-06 26.5 0.0 0.057 13.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 EIM90240.1 - 8.2e-06 25.7 0.0 0.0055 16.5 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EIM90240.1 - 1.4e-05 24.9 0.0 0.041 13.8 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HEAT PF02985.17 EIM90240.1 - 1.4e-05 24.7 1.6 0.14 12.2 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat MMR_HSR1 PF01926.18 EIM90240.1 - 1.7e-05 24.7 0.3 0.21 11.5 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EIM90240.1 - 3.1e-05 23.5 0.4 0.073 12.4 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EIM90240.1 - 4.9e-05 22.5 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EIM90240.1 - 0.0001 22.0 0.2 0.63 9.7 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Chromo PF00385.19 EIM90240.1 - 0.00011 21.8 0.3 0.00025 20.6 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 EIM90240.1 - 0.00013 22.2 0.0 1.5 9.0 0.0 3.8 4 1 1 5 5 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIM90240.1 - 0.00014 21.5 0.1 0.58 9.8 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EIM90240.1 - 0.00015 20.9 0.6 1.8 7.5 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EIM90240.1 - 0.00019 21.4 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIM90240.1 - 0.00021 21.4 0.0 0.8 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EIM90240.1 - 0.00032 20.1 0.0 1.5 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EIM90240.1 - 0.00042 20.2 0.0 0.79 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EIM90240.1 - 0.00046 19.0 0.2 0.36 9.5 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EIM90240.1 - 0.00069 19.6 5.8 0.098 12.6 0.0 4.5 4 1 0 4 4 4 1 AAA ATPase domain HEAT_EZ PF13513.1 EIM90240.1 - 0.00074 19.9 9.6 2.4 8.7 0.1 5.4 4 1 1 5 5 5 1 HEAT-like repeat Arch_ATPase PF01637.13 EIM90240.1 - 0.0011 18.7 0.3 4.7 6.8 0.0 3.6 3 0 0 3 3 3 0 Archaeal ATPase Vac14_Fab1_bd PF12755.2 EIM90240.1 - 0.0026 18.1 0.1 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region AAA_23 PF13476.1 EIM90240.1 - 0.0026 18.0 12.7 0.026 14.8 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EIM90240.1 - 0.0039 16.7 0.1 4.3 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIM90240.1 - 0.0061 15.5 0.2 2.5 6.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CLASP_N PF12348.3 EIM90240.1 - 0.016 14.5 0.3 5.5 6.2 0.0 2.3 1 1 0 2 2 2 0 CLASP N terminal AAA_14 PF13173.1 EIM90240.1 - 0.017 15.0 1.0 11 5.9 0.5 3.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIM90240.1 - 0.02 14.6 0.0 0.79 9.5 0.0 2.7 2 0 0 2 2 2 0 Dynamin family KAP_NTPase PF07693.9 EIM90240.1 - 0.024 13.6 0.7 0.18 10.7 0.0 2.6 3 0 0 3 3 3 0 KAP family P-loop domain Cnd1 PF12717.2 EIM90240.1 - 0.025 14.4 0.0 0.17 11.6 0.0 2.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 AAA_13 PF13166.1 EIM90240.1 - 0.033 12.6 3.9 2.2 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EIM90240.1 - 0.089 12.5 5.4 7.9 6.2 0.1 4.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EIM90240.1 - 0.11 11.9 3.5 2.9 7.3 0.0 3.2 4 0 0 4 4 3 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EIM90240.1 - 0.12 11.8 0.0 5.2 6.5 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_M50B PF13398.1 EIM90241.1 - 1.2e-56 191.2 20.8 1.7e-56 190.7 14.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF202 PF02656.10 EIM90241.1 - 1.1 9.5 13.1 3.1 8.0 0.6 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF202) F-box-like PF12937.2 EIM90242.1 - 2.2e-05 24.0 5.0 0.00014 21.5 0.8 2.9 2 1 0 2 2 2 1 F-box-like XPC-binding PF09280.6 EIM90242.1 - 0.29 10.6 1.4 0.6 9.6 1.0 1.4 1 0 0 1 1 1 0 XPC-binding domain TBP PF00352.16 EIM90243.1 - 5.7e-68 224.3 0.2 1.2e-33 114.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EIM90243.1 - 0.00021 21.2 1.5 1 9.4 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) DUF605 PF04652.11 EIM90243.1 - 0.5 9.7 8.9 0.57 9.5 6.2 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_3 PF01596.12 EIM90245.1 - 3.5e-46 156.8 0.0 4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIM90245.1 - 4.1e-19 69.3 0.0 2e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90245.1 - 1.1e-11 45.2 0.0 2.5e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90245.1 - 4.4e-11 42.6 0.0 7.8e-11 41.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM90245.1 - 7.2e-09 35.7 0.0 2.1e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIM90245.1 - 7.9e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EIM90245.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 EIM90245.1 - 0.0017 18.7 0.0 0.012 16.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIM90245.1 - 0.0044 16.4 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EIM90245.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EIM90245.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_88 PF07470.8 EIM90246.1 - 1.4e-16 60.4 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Med3 PF11593.3 EIM90247.1 - 0.057 12.6 0.3 0.074 12.2 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BTB PF00651.26 EIM90248.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.16 EIM90250.1 - 5.5e-14 51.8 7.8 1.1e-13 50.8 5.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger SPRR2 PF14820.1 EIM90250.1 - 0.04 13.7 1.1 0.04 13.7 0.8 3.3 4 0 0 4 4 4 0 Small proline-rich 2 MFS_1 PF07690.11 EIM90253.1 - 2.2e-20 72.6 31.0 3.3e-20 72.0 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM90253.1 - 0.001 17.7 2.7 0.001 17.7 1.9 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter PhzC-PhzF PF02567.11 EIM90254.1 - 1.2e-38 133.0 0.2 2.6e-38 131.8 0.1 1.5 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Hat1_N PF10394.4 EIM90255.1 - 6.7e-42 143.2 0.0 1.3e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 EIM90255.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.1 EIM90255.1 - 0.037 14.1 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIM90255.1 - 0.047 13.8 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpp20 PF12328.3 EIM90257.1 - 3.5e-06 26.7 0.0 4.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EIM90257.1 - 0.018 14.5 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Alba eRF1_2 PF03464.10 EIM90258.1 - 1e-45 155.3 0.0 2.2e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIM90258.1 - 1.3e-38 131.7 0.4 2.9e-38 130.6 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EIM90258.1 - 2e-26 92.1 0.0 4.2e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 GRP PF07172.6 EIM90261.1 - 0.0012 19.3 5.8 0.0016 18.9 4.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family Ras PF00071.17 EIM90262.1 - 4.4e-53 178.9 0.0 5e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM90262.1 - 3e-16 60.0 0.0 4.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM90262.1 - 1.2e-07 31.0 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM90262.1 - 0.0079 15.6 0.0 0.1 12.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Amino_oxidase PF01593.19 EIM90264.1 - 7.2e-61 206.6 0.2 4.4e-46 157.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIM90264.1 - 2.9e-11 43.2 0.4 7.7e-11 41.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM90264.1 - 3.6e-05 23.9 0.1 0.00051 20.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM90264.1 - 5.8e-05 23.4 1.3 0.0005 20.4 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM90264.1 - 5.9e-05 22.1 0.4 0.00063 18.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM90264.1 - 0.00011 21.3 0.2 0.00017 20.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EIM90264.1 - 0.0003 19.7 0.1 0.0005 19.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EIM90264.1 - 0.0031 17.1 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EIM90264.1 - 0.0043 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM90264.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EIM90264.1 - 0.03 12.7 0.1 0.053 11.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EIM90264.1 - 0.036 12.9 0.0 4.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EIM90264.1 - 0.051 12.6 0.2 0.091 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIM90264.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EIM90264.1 - 0.21 10.3 1.5 0.17 10.6 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribonuclease_3 PF00636.21 EIM90265.1 - 5.2e-38 130.0 0.0 6.5e-19 68.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIM90265.1 - 8.3e-28 96.9 0.0 2.4e-16 59.8 0.0 4.3 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EIM90265.1 - 1.5e-14 53.8 0.0 2.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM90265.1 - 1.7e-14 54.0 0.0 3.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIM90265.1 - 1.8e-14 53.3 0.0 4.3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EIM90265.1 - 4.2e-11 42.4 0.0 8.5e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 EIM90265.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF87 PF01935.12 EIM90265.1 - 0.54 10.0 1.5 1.1 9.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 RRM_1 PF00076.17 EIM90267.1 - 3.7e-35 119.3 0.0 4.4e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM90267.1 - 3.3e-17 62.2 0.0 8.6e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90267.1 - 3.9e-08 33.0 0.0 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIM90267.1 - 0.17 11.3 0.2 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain Phosducin PF02114.11 EIM90268.1 - 0.00093 17.9 0.0 0.0019 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosducin FAM176 PF14851.1 EIM90268.1 - 0.11 12.1 1.7 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 EIM90268.1 - 0.27 10.7 7.3 9 5.7 3.4 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIM90268.1 - 1.9 8.7 10.2 0.77 10.0 1.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ANAPC15 PF15243.1 EIM90268.1 - 3.2 7.8 13.1 0.73 9.9 3.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 PBP1_TM PF14812.1 EIM90268.1 - 3.6 7.9 10.0 1.2 9.4 0.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MIF PF01187.13 EIM90269.1 - 1.2e-21 76.8 0.0 1.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) zf-RING_5 PF14634.1 EIM90270.1 - 2.5e-09 36.6 6.6 2.5e-09 36.6 4.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM90270.1 - 1.7e-08 34.3 7.9 1.7e-08 34.3 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM90270.1 - 1.7e-08 34.1 7.1 1.7e-08 34.1 4.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIM90270.1 - 1.9e-08 33.8 5.1 1.9e-08 33.8 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM90270.1 - 2.9e-08 33.2 6.3 2.9e-08 33.2 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM90270.1 - 3.7e-07 29.9 8.8 3.7e-07 29.9 6.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EIM90270.1 - 3.8e-07 29.7 2.4 3.8e-07 29.7 1.7 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SAP PF02037.22 EIM90270.1 - 0.00012 21.4 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 1 SAP domain zf-RING_UBOX PF13445.1 EIM90270.1 - 0.00029 20.4 6.3 0.001 18.7 4.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIM90270.1 - 0.00076 19.0 2.2 0.00076 19.0 1.5 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EIM90270.1 - 0.0052 16.8 3.1 0.0052 16.8 2.1 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 EIM90270.1 - 0.0057 16.5 0.6 0.021 14.8 0.0 2.3 3 0 0 3 3 2 1 U-box domain Fer4_18 PF13746.1 EIM90270.1 - 0.022 15.2 3.2 0.025 15.0 0.4 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain AhpC-TSA PF00578.16 EIM90270.1 - 0.14 11.8 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AhpC/TSA family DUF329 PF03884.9 EIM90270.1 - 0.25 10.9 7.2 8.5 6.0 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF329) Prok-RING_4 PF14447.1 EIM90270.1 - 0.53 9.8 5.7 0.67 9.5 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 BRF1 PF07741.8 EIM90270.1 - 1 9.5 7.8 1.6 9.0 1.9 3.1 2 1 0 2 2 2 0 Brf1-like TBP-binding domain zf-MYND PF01753.13 EIM90273.1 - 2.9e-11 43.0 16.3 5.4e-11 42.1 11.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EIM90273.1 - 0.0018 17.8 8.4 0.0029 17.2 5.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 EIM90273.1 - 0.0087 15.9 6.4 0.024 14.4 4.4 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 EIM90273.1 - 1.5 8.1 7.9 3.5 6.9 5.5 1.6 1 0 0 1 1 1 0 Life-span regulatory factor Tom7 PF08038.7 EIM90274.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 TOM7 family DNA_primase_S PF01896.14 EIM90275.1 - 1.2e-52 177.6 0.2 2.5e-52 176.5 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit GNAT_acetyltran PF12746.2 EIM90275.1 - 0.048 12.4 0.7 0.15 10.8 0.1 1.9 2 0 0 2 2 2 0 GNAT acetyltransferase YqzH PF14164.1 EIM90275.1 - 0.059 13.2 0.4 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 YqzH-like protein Recombinase PF07508.8 EIM90275.1 - 0.14 12.3 1.7 0.34 11.1 0.0 2.4 4 0 0 4 4 4 0 Recombinase Acetyltransf_2 PF00797.12 EIM90276.1 - 2.3e-23 83.0 0.1 4.4e-21 75.5 0.1 2.7 2 1 0 2 2 2 2 N-acetyltransferase DUF1077 PF06417.7 EIM90277.1 - 5.7e-42 142.0 0.1 7e-42 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Bac_export_2 PF01312.14 EIM90277.1 - 0.044 12.6 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Senescence PF06911.7 EIM90278.1 - 2.3e-14 53.5 9.3 1.3e-09 37.9 0.8 2.4 2 0 0 2 2 2 2 Senescence-associated protein HA2 PF04408.18 EIM90280.1 - 2.5e-17 62.7 0.2 6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIM90280.1 - 4.2e-12 45.7 0.0 1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EIM90280.1 - 3.5e-09 36.4 0.0 8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EIM90280.1 - 7.6e-07 28.7 0.1 3.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIM90280.1 - 3.6e-05 23.9 0.0 9.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIM90280.1 - 0.0099 15.7 0.0 0.19 11.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EIM90280.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 EIM90280.1 - 0.05 13.8 0.0 0.21 11.8 0.0 1.8 1 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 EIM90280.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIM90280.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EIM90280.1 - 0.064 12.9 0.1 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 EIM90280.1 - 0.11 11.9 0.1 0.83 9.0 0.1 2.5 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EIM90280.1 - 0.17 11.0 0.1 0.77 8.8 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin DUF59 PF01883.14 EIM90282.1 - 4.1e-06 26.6 0.0 8.4e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 Cullin_binding PF03556.10 EIM90283.1 - 4.1e-27 94.6 0.9 5.9e-27 94.1 0.1 1.6 2 0 0 2 2 2 1 Cullin binding dsDNA_bind PF01984.15 EIM90284.1 - 1.2e-28 99.1 4.8 1.4e-28 98.9 3.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain GTP1_OBG PF01018.17 EIM90284.1 - 0.025 14.2 0.7 0.041 13.5 0.3 1.5 2 0 0 2 2 2 0 GTP1/OBG zf-RING_4 PF14570.1 EIM90285.1 - 4.9e-21 74.0 12.5 8.2e-21 73.3 8.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CAF-1_p150 PF11600.3 EIM90285.1 - 2e-05 24.0 47.7 2e-05 24.0 33.1 4.6 4 0 0 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C3HC4_3 PF13920.1 EIM90285.1 - 2.8e-05 23.6 8.4 5e-05 22.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EIM90285.1 - 0.00039 19.9 0.0 0.0013 18.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EIM90285.1 - 0.0034 17.3 13.2 0.0058 16.6 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EIM90285.1 - 0.0097 15.6 3.7 0.026 14.2 2.6 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EIM90285.1 - 0.027 14.1 3.1 0.06 13.0 2.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EIM90285.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EIM90285.1 - 0.15 11.7 13.2 0.27 10.9 9.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 EIM90285.1 - 0.27 10.5 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated 2OG-FeII_Oxy_3 PF13640.1 EIM90286.1 - 3.3e-09 37.1 0.0 5.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIM90286.1 - 0.00063 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupredoxin_1 PF13473.1 EIM90287.1 - 7.6e-06 25.7 1.3 0.064 13.1 0.1 2.8 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.15 EIM90287.1 - 0.00061 19.9 3.5 0.56 10.4 0.1 3.4 2 2 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EIM90287.1 - 0.06 13.1 8.0 1.3 8.8 0.8 3.6 2 2 0 2 2 2 0 Plastocyanin-like domain Kunitz_BPTI PF00014.18 EIM90287.1 - 0.19 11.9 3.9 11 6.3 0.3 2.5 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain G-patch PF01585.18 EIM90288.1 - 7.4e-09 35.2 1.1 1.8e-08 34.0 0.8 1.7 1 0 0 1 1 1 1 G-patch domain zf-MYND PF01753.13 EIM90290.1 - 3.6e-12 45.9 14.3 7.3e-12 44.9 9.9 1.5 1 0 0 1 1 1 1 MYND finger Lysis_col PF02402.11 EIM90290.1 - 1.3 8.6 7.6 0.62 9.7 3.2 2.2 2 0 0 2 2 2 0 Lysis protein Zn_Tnp_IS91 PF14319.1 EIM90291.1 - 1.3 8.5 7.9 2.3 7.7 4.0 2.0 1 1 0 1 1 1 0 Transposase zinc-binding domain F1F0-ATPsyn_F PF10791.4 EIM90292.1 - 4e-22 78.2 0.0 4.5e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi SHR3_chaperone PF08229.6 EIM90293.1 - 1.4e-26 92.6 0.0 1.8e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 EIM90293.1 - 0.0042 17.4 0.2 0.12 12.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) Oligomerisation PF02410.10 EIM90294.1 - 0.00055 19.9 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain CsbD PF05532.7 EIM90295.1 - 0.00057 19.5 1.5 0.00057 19.5 1.0 1.6 2 0 0 2 2 2 1 CsbD-like LETM1 PF07766.8 EIM90296.1 - 3.5e-101 337.7 0.5 3.5e-101 337.7 0.3 2.0 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EIM90296.1 - 0.00027 20.3 0.5 0.044 13.2 0.0 3.6 4 0 0 4 4 4 1 SAP domain EF-hand_8 PF13833.1 EIM90296.1 - 0.0048 16.4 0.3 0.068 12.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EIM90296.1 - 0.038 14.1 0.1 0.38 10.9 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.27 EIM90296.1 - 0.048 12.9 0.2 0.26 10.6 0.0 2.5 3 0 0 3 3 3 0 EF hand Med3 PF11593.3 EIM90296.1 - 0.47 9.6 4.6 0.86 8.7 3.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S46 PF10459.4 EIM90296.1 - 6.8 4.9 12.8 12 4.1 8.9 1.3 1 0 0 1 1 1 0 Peptidase S46 Gpi16 PF04113.9 EIM90297.1 - 3.1e-136 454.6 0.0 2.7e-134 448.2 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component MtrC PF04211.8 EIM90297.1 - 0.13 11.2 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C TF_Zn_Ribbon PF08271.7 EIM90299.1 - 0.00087 18.5 0.5 0.002 17.3 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EIM90299.1 - 0.11 12.0 0.4 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glycos_transf_1 PF00534.15 EIM90300.1 - 1.1e-20 73.7 0.0 2.2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIM90300.1 - 5.1e-09 36.3 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIM90300.1 - 2.1e-06 27.8 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 MutS_V PF00488.16 EIM90301.1 - 5.9e-82 274.5 0.3 1.9e-81 272.9 0.1 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EIM90301.1 - 1e-36 126.6 1.1 1.5e-36 126.1 0.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EIM90301.1 - 4.7e-24 84.5 0.1 9.1e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EIM90301.1 - 1.9e-10 40.9 0.0 5.3e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EIM90301.1 - 1e-07 31.9 0.0 5.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 MutS family domain IV ATP12 PF07542.6 EIM90302.1 - 4.3e-40 136.4 0.7 5.9e-40 136.0 0.1 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein DUF3025 PF11227.3 EIM90302.1 - 0.045 13.2 0.5 0.16 11.4 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3025) MUG113 PF13455.1 EIM90304.1 - 2.1e-15 56.9 0.1 6.6e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EIM90304.1 - 1e-09 38.6 0.0 1.1e-08 35.4 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain Sas10_Utp3 PF04000.10 EIM90305.1 - 2.1e-09 37.4 0.5 4.3e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HTH_5 PF01022.15 EIM90305.1 - 0.0053 16.4 0.3 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Pox_polyA_pol_N PF12630.2 EIM90305.1 - 0.044 13.8 0.2 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain UDG PF03167.14 EIM90307.1 - 3.6e-23 81.7 0.1 4.3e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PMSI1 PF15322.1 EIM90307.1 - 0.048 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative UCH_1 PF13423.1 EIM90308.1 - 2.1e-45 155.4 0.0 2.8e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EIM90308.1 - 5.5e-22 78.7 0.0 1e-21 77.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EIM90308.1 - 5.3e-09 35.5 0.0 8.6e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EIM90308.1 - 0.00084 19.1 0.9 1.4 8.9 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EIM90308.1 - 0.24 11.7 1.3 2.8 8.3 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain FMO-like PF00743.14 EIM90309.1 - 1.1e-44 152.5 0.0 1e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIM90309.1 - 1.2e-21 77.7 0.0 1.9e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM90309.1 - 1.5e-08 33.9 0.0 5.9e-07 28.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM90309.1 - 3.5e-08 33.5 0.0 5.2e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM90309.1 - 2.4e-07 30.6 0.1 3.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM90309.1 - 4.3e-07 29.8 0.0 1.5e-05 24.8 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EIM90309.1 - 0.00038 19.4 0.0 0.61 8.9 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIM90309.1 - 0.00089 18.4 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Shikimate_DH PF01488.15 EIM90309.1 - 0.0021 18.1 0.2 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIM90309.1 - 0.0035 17.7 0.2 0.23 11.8 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM90309.1 - 0.008 14.6 0.2 0.14 10.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIM90309.1 - 0.022 13.6 0.0 0.79 8.4 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EIM90309.1 - 0.063 12.3 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EIM90309.1 - 0.064 13.5 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 EIM90309.1 - 0.079 13.3 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3535 PF12054.3 EIM90310.1 - 1.9e-86 290.4 0.0 1.1e-85 287.8 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EIM90310.1 - 1.3e-77 260.5 0.1 1.8e-77 260.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EIM90310.1 - 3.4e-15 54.6 22.3 0.14 12.3 0.0 10.8 11 0 0 11 11 11 7 HEAT repeat Helicase_C PF00271.26 EIM90310.1 - 2.6e-13 49.6 0.0 9.4e-13 47.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EIM90310.1 - 3.1e-06 27.3 8.0 0.9 9.8 0.1 7.6 7 2 0 7 7 7 1 HEAT repeats CLASP_N PF12348.3 EIM90310.1 - 1.8e-05 24.2 0.0 6.7e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIM90310.1 - 4e-05 23.9 0.0 0.11 12.9 0.1 3.1 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIM90310.1 - 0.081 13.4 19.6 42 4.8 0.1 8.9 8 2 2 10 10 10 0 HEAT-like repeat Cupin_8 PF13621.1 EIM90311.1 - 1.7e-37 129.2 0.2 2.2e-37 128.9 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EIM90311.1 - 1.4e-06 27.8 0.0 7.4e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EIM90311.1 - 1.6e-05 25.1 0.1 0.002 18.3 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EIM90311.1 - 0.00027 20.3 0.0 0.0021 17.5 0.0 2.5 3 0 0 3 3 3 1 Cupin domain AraC_binding PF02311.14 EIM90311.1 - 0.041 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 EIM90311.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RabGAP-TBC PF00566.13 EIM90312.1 - 9.6e-30 103.6 0.0 4e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF2175 PF09943.4 EIM90312.1 - 2 8.5 3.5 3.6 7.6 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PAT1 PF09770.4 EIM90312.1 - 2.5 6.2 17.5 3.4 5.7 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_2 PF00890.19 EIM90313.1 - 7.5e-127 423.6 3.5 9.5e-127 423.2 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EIM90313.1 - 1.1e-45 154.6 1.1 1.7e-45 154.0 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EIM90313.1 - 3.3e-06 27.1 1.3 0.0037 17.1 0.3 3.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM90313.1 - 6e-06 25.3 1.1 0.008 15.0 1.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EIM90313.1 - 6.3e-06 25.4 0.1 0.0078 15.3 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EIM90313.1 - 6.5e-05 21.9 1.4 0.00068 18.6 1.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIM90313.1 - 0.0037 16.3 0.1 0.0064 15.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIM90313.1 - 0.074 13.0 0.2 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM90313.1 - 0.1 11.0 2.3 0.33 9.3 0.6 2.5 4 0 0 4 4 4 0 HI0933-like protein F-box-like PF12937.2 EIM90314.1 - 0.0002 20.9 0.1 0.0031 17.2 0.0 2.9 1 1 0 1 1 1 1 F-box-like zf-MYND PF01753.13 EIM90316.1 - 4e-11 42.6 10.0 9.9e-11 41.3 6.9 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM90316.1 - 0.11 12.3 4.5 0.18 11.6 2.3 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PSII_Pbs27 PF13326.1 EIM90316.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 Snf7 PF03357.16 EIM90317.1 - 1.4e-13 50.6 12.2 2.1e-13 50.0 8.5 1.3 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 EIM90317.1 - 0.48 10.2 2.5 1.8 8.3 0.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EIM90317.1 - 0.53 10.1 9.2 0.052 13.4 0.6 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 EIM90317.1 - 3.6 6.4 9.9 0.085 11.7 0.5 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SKG6 PF08693.5 EIM90318.1 - 0.0023 17.2 0.7 0.005 16.1 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GRA6 PF05084.8 EIM90318.1 - 3.8 6.9 9.7 0.41 10.1 3.4 1.6 1 1 1 2 2 2 0 Granule antigen protein (GRA6) PNTB PF02233.11 EIM90319.1 - 3.8e-169 563.3 22.5 3.8e-169 563.3 15.6 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EIM90319.1 - 6.4e-55 185.2 1.0 1.4e-54 184.1 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EIM90319.1 - 7.2e-44 149.0 0.1 2.3e-43 147.4 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EIM90319.1 - 1.1e-32 112.0 3.6 1.1e-32 112.0 2.5 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EIM90319.1 - 0.00091 18.4 0.7 2 7.5 0.1 3.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EIM90319.1 - 0.015 15.2 0.4 0.044 13.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EIM90319.1 - 0.019 14.4 1.6 0.038 13.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EIM90319.1 - 0.14 12.2 6.1 3.2 7.8 0.1 4.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EIM90319.1 - 2.1 8.4 8.4 0.32 11.0 0.9 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DHDPS PF00701.17 EIM90320.1 - 8.5e-29 100.0 0.0 2.8e-28 98.3 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family TruB_N PF01509.13 EIM90321.1 - 8.3e-45 152.5 0.0 4.6e-44 150.1 0.0 2.1 2 1 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) UCH PF00443.24 EIM90322.1 - 1.3e-55 188.4 0.0 1.8e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIM90322.1 - 7.5e-24 84.6 0.0 1.1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIM90322.1 - 7.4e-16 58.0 5.7 2.5e-15 56.3 3.9 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Trypan_PARP PF05887.6 EIM90322.1 - 0.31 10.8 21.0 0.79 9.5 14.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PI3_PI4_kinase PF00454.22 EIM90324.1 - 3.3e-33 115.1 0.0 2.2e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIM90324.1 - 1.3e-23 83.1 0.4 3.4e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Aldo_ket_red PF00248.16 EIM90325.1 - 3.7e-39 134.2 0.0 4.4e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM90326.1 - 4.5e-37 127.4 0.0 5.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nuc_sug_transp PF04142.10 EIM90328.1 - 1.9e-76 256.3 3.1 2.8e-76 255.8 2.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EIM90328.1 - 2.9e-07 29.7 4.7 4.1e-07 29.2 3.2 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EIM90328.1 - 3.6e-07 30.3 1.5 3.6e-07 30.3 1.0 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EIM90328.1 - 8.9e-07 28.6 12.4 9.4e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EIM90328.1 - 3.6e-05 23.8 0.6 3.6e-05 23.8 0.4 2.8 2 1 0 2 2 2 1 EamA-like transporter family Tic20 PF09685.5 EIM90328.1 - 0.011 15.6 1.0 0.011 15.6 0.7 2.8 2 1 0 2 2 2 0 Tic20-like protein SKG6 PF08693.5 EIM90330.1 - 0.066 12.5 1.0 0.16 11.2 0.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EIM90330.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain RAP1 PF07218.6 EIM90330.1 - 4.6 5.2 12.0 7.9 4.4 8.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Exo_endo_phos PF03372.18 EIM90331.1 - 1.1e-17 64.8 0.1 1.4e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIM90331.1 - 4.7e-06 26.2 0.0 9.3e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase TFIIE-A_C-term PF11521.3 EIM90331.1 - 0.9 9.5 3.3 1.8 8.5 2.3 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha TATR PF03430.8 EIM90331.1 - 1.3 7.5 3.6 1.9 7.0 2.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PP2C PF00481.16 EIM90334.1 - 2.3e-11 43.6 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIM90334.1 - 0.005 16.2 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Transket_pyr PF02779.19 EIM90335.1 - 1.2e-39 135.6 0.1 2.4e-39 134.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIM90335.1 - 8.3e-27 93.5 0.0 5.6e-26 90.9 0.0 2.3 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.27 EIM90336.1 - 3.2e-16 58.4 10.3 1.3e-05 24.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIM90336.1 - 0.004 15.5 0.0 0.01 14.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain TYA PF01021.14 EIM90336.1 - 0.048 13.8 2.0 0.15 12.2 1.4 1.8 1 0 0 1 1 1 0 TYA transposon protein Pyr_redox_2 PF07992.9 EIM90337.1 - 6.4e-23 81.6 0.0 1.1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM90337.1 - 9.6e-12 45.1 0.0 6.8e-08 32.8 0.0 3.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EIM90337.1 - 4.3e-11 41.2 2.0 9.1e-06 24.6 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EIM90337.1 - 9.9e-09 35.2 0.5 0.0033 17.5 0.0 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIM90337.1 - 2e-08 33.4 0.9 0.001 18.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EIM90337.1 - 1.2e-07 31.1 1.7 0.0094 15.5 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 EIM90337.1 - 5e-07 29.9 0.0 0.097 12.7 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.1 EIM90337.1 - 5.5e-07 28.6 2.3 6.9e-05 22.0 0.5 2.4 2 0 0 2 2 2 2 EF hand NAD_binding_9 PF13454.1 EIM90337.1 - 0.034 13.9 0.0 0.68 9.6 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EIM90337.1 - 0.07 13.3 0.1 0.44 10.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding EF-hand_4 PF12763.2 EIM90337.1 - 0.27 10.9 2.7 5.3 6.8 0.4 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.17 EIM90339.1 - 5.5e-59 198.1 0.4 7.1e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM90339.1 - 5.6e-23 81.7 0.2 1.1e-22 80.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIM90339.1 - 1.6e-16 60.0 0.6 1.9e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM90339.1 - 2.6e-07 30.2 0.3 2.2e-06 27.2 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIM90339.1 - 2e-06 27.1 0.1 5e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIM90339.1 - 3.2e-06 26.4 0.6 4.2e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM90339.1 - 5.4e-06 26.3 0.1 1.9e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM90339.1 - 0.00017 20.8 0.1 0.05 12.8 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EIM90339.1 - 0.0079 16.0 0.1 0.86 9.4 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 EIM90339.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EIM90339.1 - 0.029 14.5 0.0 0.9 9.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM90339.1 - 0.036 13.9 0.4 0.093 12.6 0.2 1.8 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EIM90339.1 - 0.063 12.9 0.2 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EIM90339.1 - 0.082 12.3 0.8 0.31 10.5 0.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MTHFR PF02219.12 EIM90340.1 - 2.6e-108 361.4 0.0 3.3e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ANAPC15 PF15243.1 EIM90341.1 - 0.0033 17.4 0.0 0.0033 17.4 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 15 ATP-synt_ab PF00006.20 EIM90342.1 - 1.4e-63 214.2 0.1 4.3e-63 212.6 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIM90342.1 - 1.1e-24 87.0 0.4 2e-24 86.2 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIM90342.1 - 3.2e-23 81.7 0.9 3.2e-23 81.7 0.6 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EIM90342.1 - 0.0058 16.8 0.0 0.34 11.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EIM90342.1 - 0.011 15.4 0.2 1.9 8.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EIM90342.1 - 0.015 14.2 1.0 0.029 13.2 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EIM90342.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM90342.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EIM90342.1 - 0.025 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 EIM90342.1 - 0.037 13.1 0.1 0.07 12.2 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EIM90342.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM90342.1 - 0.047 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIM90342.1 - 0.06 13.3 1.2 0.14 12.1 0.0 2.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 EIM90342.1 - 0.14 12.0 0.3 10 5.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain Clp1 PF06807.9 EIM90343.1 - 4.4e-22 78.7 0.0 9.9e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EIM90343.1 - 9.5e-09 35.0 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EIM90343.1 - 0.034 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIM90343.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EIM90343.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EIM90343.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3129 PF11327.3 EIM90344.1 - 1.3e-52 178.3 11.6 1.6e-52 178.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3716 PF12511.3 EIM90344.1 - 0.086 12.4 0.6 0.2 11.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) MOFRL PF05161.8 EIM90344.1 - 0.11 12.5 1.6 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 MOFRL family TAP42 PF04177.7 EIM90345.1 - 1.1e-71 241.5 1.4 1.3e-71 241.3 1.0 1.0 1 0 0 1 1 1 1 TAP42-like family POT1 PF02765.12 EIM90346.1 - 1e-07 31.9 0.0 2.8e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 YadA_stalk PF05662.9 EIM90346.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.9 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin Peptidase_S8 PF00082.17 EIM90347.1 - 2.2e-46 158.2 1.1 4.6e-46 157.2 0.6 1.6 1 1 1 2 2 2 1 Subtilase family P_proprotein PF01483.15 EIM90347.1 - 1.7e-27 95.0 0.3 3.5e-27 94.0 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF2914 PF11141.3 EIM90347.1 - 0.032 13.7 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) MCM PF00493.18 EIM90348.1 - 2.9e-136 453.6 0.2 4.6e-135 449.6 0.1 2.2 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIM90348.1 - 1.3e-25 90.2 0.5 5e-25 88.3 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EIM90348.1 - 1.4e-09 37.8 0.2 1.4e-06 28.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIM90348.1 - 1.3e-07 31.0 0.1 1.1e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 EIM90348.1 - 0.0068 16.7 0.9 0.0068 16.7 0.6 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIM90348.1 - 0.025 14.2 0.0 0.089 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIM90348.1 - 0.046 13.2 0.5 0.78 9.1 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_polI_A14 PF08203.6 EIM90348.1 - 0.083 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Drc1-Sld2 PF11719.3 EIM90348.1 - 0.31 10.1 3.2 0.53 9.3 2.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein DNA_methylase PF00145.12 EIM90349.1 - 4.3e-49 167.4 0.0 9.6e-49 166.2 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EIM90349.1 - 6.1e-21 74.3 0.2 3.6e-11 42.8 0.0 2.9 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.3 EIM90349.1 - 2.1e-08 34.0 0.0 4.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Peptidase_S24 PF00717.18 EIM90349.1 - 0.05 13.2 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase S24-like APG9 PF04109.11 EIM90350.1 - 1.2e-159 531.1 0.1 1.6e-159 530.8 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF77 PF01910.12 EIM90351.1 - 8.2e-30 102.3 0.0 9.6e-30 102.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EIM90351.1 - 8.4e-05 22.6 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family adh_short PF00106.20 EIM90352.1 - 2.9e-20 72.8 0.0 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90352.1 - 1.7e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90352.1 - 8.4e-08 32.0 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIM90352.1 - 0.019 14.6 0.1 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIM90352.1 - 0.05 12.7 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 EIM90353.1 - 1e-52 178.8 0.0 1.3e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90353.1 - 1.2e-45 155.6 0.0 1.5e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90353.1 - 0.0035 17.1 0.1 0.0094 15.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM90353.1 - 0.0082 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SAP PF02037.22 EIM90353.1 - 0.016 14.7 0.1 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain Seadorna_VP7 PF07387.6 EIM90353.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DTHCT PF08070.6 EIM90353.1 - 0.19 12.4 2.1 1.5 9.5 0.1 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region Mito_carr PF00153.22 EIM90354.1 - 4e-53 177.1 3.5 1.4e-18 66.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1c PF00749.16 EIM90355.1 - 1.4e-107 359.0 0.0 1.8e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIM90355.1 - 1e-36 126.2 0.0 2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EIM90355.1 - 6.7e-07 29.7 0.4 4e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM90355.1 - 0.00016 21.6 0.0 0.00049 20.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIM90355.1 - 0.00088 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HMGL-like PF00682.14 EIM90356.1 - 2e-58 197.8 0.0 3.4e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EIM90356.1 - 6.1e-35 119.9 0.0 1.9e-18 66.5 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain AAA PF00004.24 EIM90357.1 - 5.4e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIM90357.1 - 8.1e-09 34.6 0.1 2e-05 23.5 0.0 2.6 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EIM90357.1 - 4.7e-06 25.8 0.0 2.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIM90357.1 - 4.3e-05 23.6 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIM90357.1 - 6.5e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIM90357.1 - 7.2e-05 23.5 0.0 0.00025 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM90357.1 - 0.00011 21.8 0.9 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EIM90357.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM90357.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM90357.1 - 0.0031 17.5 0.0 0.0095 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EIM90357.1 - 0.0064 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIM90357.1 - 0.0092 15.4 0.1 1.7 8.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM90357.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EIM90357.1 - 0.019 14.6 0.1 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 NTPase IstB_IS21 PF01695.12 EIM90357.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EIM90357.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EIM90357.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EIM90357.1 - 0.15 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MFS_1 PF07690.11 EIM90358.1 - 4.1e-23 81.6 28.2 3e-22 78.8 20.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CRPA PF05745.6 EIM90358.1 - 0.52 10.0 4.5 5.3 6.8 0.5 2.4 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) His_Phos_1 PF00300.17 EIM90359.1 - 7.7e-20 71.5 0.0 6.6e-19 68.5 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TAFII55_N PF04658.8 EIM90361.1 - 1.7e-54 183.6 0.2 3.7e-54 182.6 0.1 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Macoilin PF09726.4 EIM90361.1 - 0.3 9.3 6.1 0.38 8.9 4.2 1.4 1 1 0 1 1 1 0 Transmembrane protein Tom37_C PF11801.3 EIM90362.1 - 1.6e-14 54.1 0.0 2.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EIM90362.1 - 6.9e-11 42.2 0.1 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EIM90362.1 - 0.00011 22.0 0.2 0.00034 20.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OTU PF02338.14 EIM90363.1 - 3.1e-10 40.6 0.0 5.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Chromo PF00385.19 EIM90364.1 - 0.046 13.3 2.0 0.077 12.6 0.6 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain HemX PF04375.9 EIM90364.1 - 0.052 12.1 8.1 0.11 11.0 5.6 1.6 1 0 0 1 1 1 0 HemX Fib_alpha PF08702.5 EIM90364.1 - 0.069 13.2 4.4 0.17 12.0 3.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FadA PF09403.5 EIM90364.1 - 0.12 12.3 6.4 0.25 11.3 4.4 1.5 1 0 0 1 1 1 0 Adhesion protein FadA APG6 PF04111.7 EIM90364.1 - 1.4 7.8 12.9 2.1 7.3 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 EIM90364.1 - 3.6 6.4 12.2 14 4.5 8.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sugar_tr PF00083.19 EIM90365.1 - 2.7e-92 309.6 25.9 3.2e-92 309.4 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM90365.1 - 6.4e-34 117.2 29.2 9.7e-34 116.6 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIM90365.1 - 2.7e-05 22.4 10.6 0.0027 15.8 1.2 3.0 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EIM90365.1 - 0.03 14.1 7.7 0.11 12.2 0.1 3.0 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 EIM90365.1 - 0.37 8.8 12.6 0.005 15.0 2.9 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_2 PF04550.7 EIM90365.1 - 4.6 7.4 7.2 1.3 9.1 0.4 2.9 3 0 0 3 3 3 0 Phage holin family 2 HECT PF00632.20 EIM90366.1 - 2.9e-87 292.7 0.0 4.2e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIM90366.1 - 1.1e-34 117.8 21.5 1.4e-11 43.9 4.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIM90366.1 - 4.9e-16 58.3 0.1 1.2e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain PAT1 PF09770.4 EIM90366.1 - 0.92 7.6 7.8 1.3 7.1 5.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 EIM90367.1 - 3.5 5.7 12.4 3.4 5.7 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 EIM90367.1 - 7.7 5.3 12.2 8.8 5.1 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF605 PF04652.11 EIM90367.1 - 7.8 5.7 20.1 8.8 5.6 14.0 1.0 1 0 0 1 1 1 0 Vta1 like Nt_Gln_amidase PF09764.4 EIM90368.1 - 5.8e-21 74.6 2.0 1.7e-20 73.0 1.4 1.6 1 1 0 1 1 1 1 N-terminal glutamine amidase Apc3 PF12895.2 EIM90368.1 - 0.071 13.2 0.2 0.096 12.8 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 UQ_con PF00179.21 EIM90371.1 - 2.8e-41 140.2 0.1 3.2e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM90371.1 - 0.00035 20.3 0.0 0.00043 20.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIM90371.1 - 0.00094 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EIM90371.1 - 0.0016 18.2 0.1 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain SPRY PF00622.23 EIM90372.1 - 6.7e-07 29.4 0.1 2.9e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 SPRY domain PhoD PF09423.5 EIM90373.1 - 4.2e-05 22.3 0.1 0.0053 15.3 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase PROL5-SMR PF15621.1 EIM90373.1 - 8.9 6.7 17.8 0.36 11.2 8.0 1.9 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family CAP_N PF01213.14 EIM90374.1 - 3.6e-74 249.8 0.0 5.2e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EIM90374.1 - 1.6e-56 190.0 5.6 2.2e-56 189.6 3.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EIM90374.1 - 0.017 14.5 3.4 0.019 14.3 1.6 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C RF-1 PF00472.15 EIM90375.1 - 4.4e-25 87.7 4.8 4.4e-25 87.7 3.4 1.8 2 0 0 2 2 2 1 RF-1 domain Linker_histone PF00538.14 EIM90376.1 - 5.8e-16 58.3 0.0 1.5e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.6 EIM90376.1 - 0.41 10.4 89.1 0.45 10.3 4.3 2.4 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Herpes_BLLF1 PF05109.8 EIM90376.1 - 9.6 4.0 26.1 14 3.4 18.1 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) EI24 PF07264.6 EIM90377.1 - 7.8e-29 100.6 13.9 9.9e-29 100.3 9.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.19 EIM90378.1 - 3.1e-26 92.3 16.7 3.1e-26 92.3 11.6 2.0 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EIM90378.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Lipase_GDSL_2 PF13472.1 EIM90379.1 - 2.6e-26 92.8 0.0 3.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIM90379.1 - 1.3e-22 80.7 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.15 EIM90380.1 - 3.1e-12 46.8 0.0 5.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain AAA PF00004.24 EIM90382.1 - 7e-20 71.5 0.0 1.7e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIM90382.1 - 0.061 11.9 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EIM90382.1 - 0.1 12.3 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EIM90382.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EIM90382.1 - 0.11 12.5 0.0 0.51 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIM90382.1 - 0.16 11.9 0.2 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Pox_MCEL PF03291.11 EIM90383.1 - 1.6e-80 270.4 0.0 2.2e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EIM90383.1 - 2.5e-08 34.2 0.0 4.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM90383.1 - 1.9e-07 30.9 0.0 4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90383.1 - 3.6e-07 29.8 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90383.1 - 3.8e-07 30.6 0.0 7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM90383.1 - 9.9e-06 25.9 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM90383.1 - 3.7e-05 24.0 0.0 7.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM90383.1 - 0.023 14.7 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIM90383.1 - 0.22 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF1180 PF06679.7 EIM90384.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TEA PF01285.13 EIM90386.1 - 5.2e-25 88.4 0.1 8.7e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EIM90386.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain ER_lumen_recept PF00810.13 EIM90387.1 - 5.3e-08 33.4 1.5 5.3e-08 33.4 1.0 2.1 1 1 1 2 2 2 1 ER lumen protein retaining receptor Bestrophin PF01062.16 EIM90388.1 - 2.9e-50 170.8 0.5 1.3e-28 99.8 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3295 PF11702.3 EIM90388.1 - 0.0025 16.8 0.3 0.0036 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF2074 PF09847.4 EIM90388.1 - 0.014 14.1 1.8 0.021 13.5 1.3 1.2 1 0 0 1 1 1 0 Predicted permease (DUF2074) S-AdoMet_synt_M PF02772.11 EIM90388.1 - 0.022 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain 2Fe-2S_thioredx PF01257.14 EIM90389.1 - 2.4e-58 195.8 0.0 2.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3786 PF12654.2 EIM90389.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Telomere_reg-2 PF10193.4 EIM90390.1 - 8.2e-26 90.5 0.0 1.9e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Linker_histone PF00538.14 EIM90391.1 - 7.4e-11 41.9 0.0 1.9e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family AMP-binding PF00501.23 EIM90392.1 - 6.7e-15 54.3 0.2 2.3e-14 52.6 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Potassium_chann PF11404.3 EIM90393.1 - 1.2 9.0 5.9 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Potassium voltage-gated channel DPBB_1 PF03330.13 EIM90394.1 - 1.5e-06 28.1 0.0 8.5e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM90394.1 - 0.0055 16.3 0.2 0.0067 16.0 0.1 1.2 1 0 0 1 1 1 1 Barwin family Cys_rich_CPXG PF14255.1 EIM90394.1 - 0.038 13.8 0.2 0.06 13.1 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF2148 PF09918.4 EIM90394.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) YjbE PF11106.3 EIM90394.1 - 0.12 12.3 1.5 0.13 12.2 0.2 1.7 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE Linker_histone PF00538.14 EIM90395.1 - 1.5e-11 44.1 0.0 3.7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Pkinase PF00069.20 EIM90396.1 - 1.2e-48 165.5 0.0 1.5e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90396.1 - 4.8e-18 65.1 0.0 7.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM90396.1 - 3.2e-07 29.6 0.0 4.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM90396.1 - 5.9e-05 22.2 0.0 9.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM90396.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PVL_ORF50 PF07768.6 EIM90397.1 - 1.2 9.1 5.2 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 PVL ORF-50-like family RRM_1 PF00076.17 EIM90398.1 - 6.1e-25 86.6 0.0 2.1e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIM90398.1 - 7.2e-20 69.2 0.0 0.00017 20.8 0.0 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EIM90398.1 - 9e-18 64.0 0.0 4.6e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90398.1 - 3.5e-13 49.1 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_21 PF13276.1 EIM90398.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain Nab6_mRNP_bdg PF10567.4 EIM90398.1 - 0.66 8.9 0.0 1.1 8.1 0.0 1.2 1 0 0 1 1 1 0 RNA-recognition motif Mog1 PF04603.7 EIM90400.1 - 4.3e-33 114.2 0.1 5.9e-33 113.7 0.1 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.8 EIM90401.1 - 3.2e-31 107.9 0.0 6.9e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Flagellin_N PF00669.15 EIM90401.1 - 0.0019 17.9 13.7 0.0024 17.6 0.6 3.1 3 1 0 3 3 3 2 Bacterial flagellin N-terminal helical region Seryl_tRNA_N PF02403.17 EIM90401.1 - 0.026 14.5 29.9 0.029 14.3 5.6 3.8 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EIM90401.1 - 0.03 14.2 1.1 0.03 14.2 0.8 4.9 2 2 2 5 5 5 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 EIM90401.1 - 0.064 13.3 22.6 0.03 14.4 3.3 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family VIT1 PF01988.14 EIM90401.1 - 0.41 10.0 5.5 0.21 11.0 0.1 2.4 2 0 0 2 2 2 0 VIT family Reo_sigmaC PF04582.7 EIM90401.1 - 1.2 8.1 10.2 1.3 8.1 1.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 EIM90401.1 - 5.3 5.9 37.1 0.34 9.9 5.3 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 Spc24 PF08286.6 EIM90401.1 - 6.5 6.4 25.5 0.1 12.2 4.6 4.0 3 2 1 4 4 4 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 EIM90401.1 - 7.7 6.8 10.4 0.57 10.4 0.3 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein LktC PF06261.6 EIM90402.1 - 0.012 15.2 0.1 0.096 12.3 0.1 2.1 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC DUF2235 PF09994.4 EIM90403.1 - 5e-64 216.3 0.0 6.5e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TFIIA PF03153.8 EIM90404.1 - 5.6 6.7 9.1 6.5 6.5 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.13 EIM90405.1 - 1.8e-19 69.6 14.5 5.2e-05 23.3 0.3 8.4 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIM90405.1 - 3.1e-11 42.5 20.1 1.3e-06 27.8 0.1 7.7 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat DUF3599 PF12206.3 EIM90406.1 - 0.052 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) DSBA PF01323.15 EIM90406.1 - 0.11 12.0 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glyco_hydro_42M PF08532.5 EIM90406.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.5 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain F-box-like PF12937.2 EIM90407.1 - 1.3e-05 24.8 0.0 5.2e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 F-box-like Med9 PF07544.8 EIM90410.1 - 0.00098 18.8 9.2 0.014 15.1 0.5 3.3 4 0 0 4 4 4 2 RNA polymerase II transcription mediator complex subunit 9 DUF77 PF01910.12 EIM90410.1 - 0.034 13.8 0.3 0.034 13.8 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF77 Kinesin-relat_1 PF12711.2 EIM90410.1 - 0.076 13.4 0.2 0.076 13.4 0.2 3.3 3 0 0 3 3 3 0 Kinesin motor Prominin PF05478.6 EIM90410.1 - 0.34 8.3 2.3 0.58 7.6 1.6 1.3 1 0 0 1 1 1 0 Prominin WD40_alt PF14077.1 EIM90410.1 - 0.36 10.5 8.1 0.1 12.2 2.2 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Orbi_VP5 PF00901.12 EIM90410.1 - 0.41 8.7 9.8 0.032 12.4 3.0 1.8 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 DUF4140 PF13600.1 EIM90410.1 - 0.67 10.4 10.5 1.8 9.0 0.2 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EIM90410.1 - 1 9.7 14.7 6.1 7.2 3.6 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF972) DUF3186 PF11382.3 EIM90410.1 - 1 8.4 5.5 1.3 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) TBPIP PF07106.8 EIM90410.1 - 1.3 8.4 14.3 0.19 11.2 0.5 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EIM90410.1 - 1.9 8.0 13.8 3.1 7.3 2.3 2.9 3 0 0 3 3 3 0 IncA protein Bacillus_HBL PF05791.6 EIM90410.1 - 2 7.7 7.8 3.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 EIM90410.1 - 2 8.3 24.2 1.2 9.1 8.2 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Vfa1 PF08432.5 EIM90410.1 - 3 7.8 22.9 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.4 EIM90410.1 - 3.2 6.6 21.9 1.5 7.6 0.8 3.1 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2383 PF09537.5 EIM90410.1 - 3.4 7.9 10.9 0.69 10.1 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) HALZ PF02183.13 EIM90410.1 - 4.1 7.1 12.0 3.1 7.6 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper RTBV_P46 PF06216.6 EIM90410.1 - 4.8 5.9 6.3 9.3 4.9 1.2 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Seryl_tRNA_N PF02403.17 EIM90410.1 - 5.1 7.1 25.6 6.3 6.8 0.4 4.0 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 EIM90410.1 - 6 7.2 20.4 15 5.9 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 EIM90410.1 - 7.6 6.5 18.3 1.3 8.9 0.6 3.6 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.19 EIM90410.1 - 8.8 5.9 6.9 2.2 7.9 0.7 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD HAUS6_N PF14661.1 EIM90412.1 - 4.3e-07 29.5 0.4 0.0037 16.6 0.0 3.4 3 1 0 3 3 3 2 HAUS augmin-like complex subunit 6 N-terminus Cpn60_TCP1 PF00118.19 EIM90413.1 - 6.7e-139 463.6 10.2 7.6e-139 463.4 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EIM90413.1 - 0.0084 15.3 0.1 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination TPR_11 PF13414.1 EIM90414.1 - 2e-31 107.4 16.4 6.1e-08 32.1 1.2 7.8 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 EIM90414.1 - 7.2e-27 91.1 9.7 0.00027 20.6 0.2 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EIM90414.1 - 1e-24 85.0 4.9 1.5e-07 30.7 0.3 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIM90414.1 - 6e-22 77.7 41.5 7.8e-06 26.4 0.5 8.9 8 2 2 10 10 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EIM90414.1 - 1.7e-18 65.1 0.5 0.046 13.9 0.0 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EIM90414.1 - 1.2e-17 63.7 10.8 1.5e-10 41.0 0.1 5.3 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIM90414.1 - 1.5e-17 62.5 19.9 0.0023 18.3 0.1 10.5 5 2 6 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIM90414.1 - 1.5e-17 63.6 9.8 0.00021 21.5 0.0 8.1 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIM90414.1 - 6.8e-14 50.5 0.1 0.015 15.0 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM90414.1 - 1.9e-12 46.9 16.3 2.1e-05 24.3 0.1 7.1 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EIM90414.1 - 1.7e-08 34.3 13.1 2.9 8.5 0.0 8.7 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM90414.1 - 1.2e-06 28.3 14.6 0.00081 19.1 0.2 6.1 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIM90414.1 - 2.4e-06 26.8 14.5 0.17 10.9 0.1 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIM90414.1 - 7.3e-06 25.4 6.5 16 5.6 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat SMAP PF15477.1 EIM90414.1 - 0.03 14.5 2.3 3.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Small acidic protein family TPR_10 PF13374.1 EIM90414.1 - 0.039 13.9 10.7 21 5.2 0.4 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SOG2 PF10428.4 EIM90414.1 - 0.047 12.3 11.9 0.054 12.1 7.5 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein BTAD PF03704.12 EIM90414.1 - 0.49 10.6 15.8 11 6.2 0.0 5.7 5 1 0 6 6 6 0 Bacterial transcriptional activator domain PPR_3 PF13812.1 EIM90414.1 - 0.58 10.5 3.1 96 3.6 0.0 4.4 4 0 0 4 4 3 0 Pentatricopeptide repeat domain SRR1 PF07985.7 EIM90416.1 - 3.6e-15 55.6 0.1 5.9e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 SRR1 PUA PF01472.15 EIM90417.1 - 1.5e-15 56.6 0.0 2.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.20 EIM90418.1 - 3.8e-25 88.5 0.0 5.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90418.1 - 7.8e-11 41.5 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM90418.1 - 7.6e-05 21.8 0.0 0.00016 20.7 0.0 1.4 1 1 0 2 2 2 1 Kinase-like Trp_halogenase PF04820.9 EIM90418.1 - 0.04 12.5 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase APH PF01636.18 EIM90418.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM90418.1 - 0.059 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM90418.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DPBB_1 PF03330.13 EIM90419.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cys_rich_CPXG PF14255.1 EIM90419.1 - 0.084 12.7 0.6 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG Barwin PF00967.12 EIM90419.1 - 0.38 10.4 0.1 0.38 10.4 0.0 2.4 2 1 1 3 3 3 0 Barwin family HSP70 PF00012.15 EIM90420.1 - 2.4e-244 811.7 4.9 3e-244 811.4 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIM90420.1 - 1.9e-16 59.5 0.2 2.1e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIM90420.1 - 0.0044 15.8 0.9 0.025 13.4 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 EIM90420.1 - 0.0044 16.3 0.1 0.88 8.8 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Ad_cyc_g-alpha PF08509.6 EIM90420.1 - 0.033 13.5 0.1 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain StbA PF06406.6 EIM90420.1 - 0.043 12.7 0.0 0.09 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 EIM90420.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1539 PF07560.6 EIM90420.1 - 0.092 12.6 0.2 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) QRPTase_N PF02749.11 EIM90420.1 - 0.1 12.4 0.2 7.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Hydantoinase_A PF01968.13 EIM90420.1 - 0.24 10.4 3.0 0.58 9.1 0.2 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Chorismate_bind PF00425.13 EIM90421.1 - 6.7e-88 294.3 0.0 1.3e-87 293.3 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EIM90421.1 - 1.3e-29 102.9 0.0 7.3e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.10 EIM90422.1 - 9.2e-49 165.4 0.0 2.7e-48 163.9 0.0 1.8 1 0 0 1 1 1 1 SHQ1 protein PIH1 PF08190.7 EIM90422.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 EIM90422.1 - 0.00043 20.7 0.0 0.00073 20.0 0.0 1.4 1 0 0 1 1 1 1 CS domain Pkinase PF00069.20 EIM90423.1 - 7.4e-41 140.0 0.0 9e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90423.1 - 3.9e-20 72.0 0.0 5.8e-20 71.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM90423.1 - 0.00035 19.6 0.0 0.00066 18.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIM90423.1 - 0.0039 16.2 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM90423.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.15 EIM90424.1 - 4.2e-67 225.5 3.8 4.2e-67 225.5 2.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIM90424.1 - 2.5e-44 150.9 9.2 2.5e-44 150.9 6.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIM90424.1 - 2.5e-31 109.8 0.0 6.7e-30 105.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM90424.1 - 4.2e-22 77.9 0.0 8.1e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIM90424.1 - 5.3e-22 77.0 0.2 2.8e-21 74.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIM90424.1 - 2.4e-14 53.9 0.0 5.2e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIM90424.1 - 5.3e-06 26.1 2.4 7.4e-06 25.7 0.8 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIM90424.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Lactamase_B PF00753.22 EIM90426.1 - 2.2e-12 47.0 3.2 2.6e-11 43.5 2.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIM90426.1 - 1.8e-05 24.3 0.6 5.4e-05 22.8 0.4 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DPBB_1 PF03330.13 EIM90428.1 - 0.002 18.1 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1180 PF06679.7 EIM90428.1 - 4.4 7.1 12.2 6.9 6.5 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DPBB_1 PF03330.13 EIM90429.1 - 0.0011 18.9 0.2 0.0052 16.7 0.0 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM90429.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Barwin family DUF1079 PF06435.6 EIM90430.1 - 0.13 12.2 0.4 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) AAA PF00004.24 EIM90431.1 - 8.5e-15 55.1 0.0 3.1e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIM90431.1 - 8.4e-13 48.2 0.0 5.7e-12 45.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EIM90431.1 - 1.9e-09 37.3 0.1 4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EIM90431.1 - 5.1e-09 35.3 0.0 7.8e-07 28.1 0.0 2.2 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIM90431.1 - 2.5e-07 30.9 0.0 9.1e-07 29.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIM90431.1 - 4e-06 26.9 0.1 6.6e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIM90431.1 - 3.8e-05 22.8 0.0 8.7e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIM90431.1 - 4.6e-05 23.0 0.0 0.00018 21.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EIM90431.1 - 9.5e-05 22.0 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIM90431.1 - 0.00018 21.1 0.0 0.0009 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIM90431.1 - 0.00044 19.9 0.0 0.0023 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIM90431.1 - 0.00059 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIM90431.1 - 0.0027 17.2 0.0 0.0086 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIM90431.1 - 0.0029 16.7 0.0 0.067 12.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EIM90431.1 - 0.0039 16.2 0.0 0.0067 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EIM90431.1 - 0.0046 17.7 0.0 0.048 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EIM90431.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 EIM90431.1 - 0.022 14.1 0.0 0.33 10.3 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EIM90431.1 - 0.035 13.4 0.0 0.088 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EIM90431.1 - 0.037 13.5 0.1 0.39 10.2 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.8 EIM90431.1 - 0.038 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EIM90431.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM90431.1 - 0.066 13.0 0.0 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIM90431.1 - 0.1 12.9 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIM90431.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CAF1A PF12253.3 EIM90432.1 - 4.1e-21 74.8 6.7 4.1e-21 74.8 4.6 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A TAF1D PF15333.1 EIM90433.1 - 0.19 11.5 1.5 0.28 10.9 1.0 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D PRP21_like_P PF12230.3 EIM90434.1 - 5.5e-54 183.0 21.9 5.5e-54 183.0 15.2 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EIM90434.1 - 7.4e-31 105.5 0.7 3.6e-15 55.3 0.0 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EIM90434.1 - 0.00023 20.4 0.0 0.00044 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIM90434.1 - 0.035 13.7 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Med19 PF10278.4 EIM90434.1 - 4.7 6.8 17.1 0.1 12.2 0.4 3.3 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 L31 PF09784.4 EIM90435.1 - 2.8e-37 126.9 0.3 3.1e-37 126.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 EIM90436.1 - 2.8e-55 187.0 13.0 9.5e-36 123.1 0.1 3.1 3 0 0 3 3 3 3 U3-containing 90S pre-ribosomal complex subunit DUF1168 PF06658.7 EIM90436.1 - 0.01 15.3 9.6 0.019 14.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NST1 PF13945.1 EIM90436.1 - 0.096 12.7 8.3 0.15 12.1 5.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator U3_snoRNA_assoc PF08297.6 EIM90436.1 - 0.11 12.7 7.2 0.48 10.7 3.7 2.4 2 0 0 2 2 2 0 U3 snoRNA associated TATR PF03430.8 EIM90436.1 - 0.28 9.7 1.7 0.38 9.3 0.7 1.4 2 0 0 2 2 2 0 Trans-activating transcriptional regulator ATP-synt_E PF05680.7 EIM90436.1 - 1.4 8.8 8.3 2.7 8.0 5.7 1.4 1 0 0 1 1 1 0 ATP synthase E chain CDC45 PF02724.9 EIM90436.1 - 2.8 5.8 7.2 3.6 5.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EIM90436.1 - 2.9 6.4 7.3 4.2 5.9 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.7 EIM90436.1 - 9.1 4.5 20.1 0.24 9.7 8.4 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_T PF00929.19 EIM90437.1 - 2.9e-13 50.4 0.0 9.9e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DUF2360 PF10152.4 EIM90437.1 - 2.7 8.2 8.0 6 7.1 5.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CRM1_C PF08767.6 EIM90438.1 - 6.2e-128 426.2 0.0 6.2e-128 426.2 0.0 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EIM90438.1 - 6.7e-42 142.8 10.1 1.3e-41 141.9 5.2 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EIM90438.1 - 2.1e-13 49.9 0.0 8.8e-13 47.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain ADH_zinc_N_2 PF13602.1 EIM90439.1 - 6.6e-19 69.0 0.0 2.5e-18 67.1 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM90439.1 - 6e-13 48.4 0.0 2.3e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM90439.1 - 0.077 12.7 0.0 2.3 8.0 0.0 2.5 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain Spc24 PF08286.6 EIM90440.1 - 1.9e-14 53.3 0.3 1.7e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APH_6_hur PF04655.9 EIM90440.1 - 0.0015 17.7 0.3 0.0015 17.7 0.2 1.8 1 1 1 2 2 2 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMF_DNA_bd PF12329.3 EIM90440.1 - 0.024 14.4 3.1 0.024 14.4 2.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HTH_22 PF13309.1 EIM90440.1 - 0.053 13.2 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain APG6 PF04111.7 EIM90440.1 - 0.14 11.2 4.3 0.17 10.9 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pilin_PilA PF14245.1 EIM90440.1 - 0.14 12.6 2.0 1.4 9.4 0.2 2.3 1 1 0 2 2 2 0 Type IV pilin PilA DUF342 PF03961.8 EIM90440.1 - 0.19 10.0 1.8 0.27 9.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EIM90440.1 - 0.24 10.2 2.2 0.33 9.8 1.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EIM90440.1 - 0.96 9.3 6.5 1.4 8.8 4.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T2SM PF04612.7 EIM90440.1 - 0.97 9.2 9.9 2.7 7.7 1.3 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M HlyD PF00529.15 EIM90440.1 - 1.5 8.0 8.9 2.1 7.5 6.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DivIC PF04977.10 EIM90440.1 - 3.5 7.1 10.0 9.4 5.8 2.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 EIM90440.1 - 7.1 6.6 8.3 13 5.8 5.7 1.4 1 1 0 1 1 1 0 DivIVA protein RE_SacI PF09566.5 EIM90441.1 - 0.08 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 SacI restriction endonuclease EamA PF00892.15 EIM90443.1 - 2.5e-09 37.2 26.2 0.0001 22.3 3.5 3.2 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIM90443.1 - 2.2e-08 33.5 0.3 3.8e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EIM90443.1 - 2.1e-07 30.1 5.4 3.5e-07 29.4 3.7 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIM90443.1 - 6.9e-05 22.5 13.6 0.03 13.9 4.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EIM90443.1 - 0.0026 17.9 6.3 0.0026 17.9 4.4 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter CBP4 PF07960.6 EIM90445.1 - 1.6e-11 43.9 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 EIM90445.1 - 0.018 14.7 0.1 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) YkyB PF14177.1 EIM90445.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 YkyB-like protein F-box-like PF12937.2 EIM90446.1 - 4.8e-08 32.6 0.2 2e-07 30.5 0.2 2.2 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 EIM90447.1 - 4e-22 78.9 2.0 5.9e-22 78.3 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90447.1 - 8.3e-13 48.6 0.3 1.1e-12 48.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM90447.1 - 4.2e-06 26.9 0.2 6.9e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM90447.1 - 7.4e-06 25.7 0.6 1.2e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIM90447.1 - 0.014 15.0 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EIM90447.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EIM90447.1 - 0.024 14.0 0.1 0.049 13.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EIM90447.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EIM90447.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Alginate_lyase PF05426.7 EIM90448.1 - 5.3e-15 55.5 9.7 1.3e-14 54.1 6.7 1.5 1 1 0 1 1 1 1 Alginate lyase UQ_con PF00179.21 EIM90449.1 - 6.6e-18 64.4 0.0 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rubredoxin PF00301.15 EIM90449.1 - 0.021 14.6 2.0 0.16 11.8 0.6 2.4 2 0 0 2 2 2 0 Rubredoxin RWD PF05773.17 EIM90449.1 - 0.061 13.2 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 RWD domain Transcrip_reg PF01709.15 EIM90450.1 - 2.6e-61 206.7 1.2 3e-61 206.5 0.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator THUMP PF02926.12 EIM90450.1 - 0.02 14.7 0.6 0.17 11.7 0.4 2.2 1 1 0 1 1 1 0 THUMP domain ABC_tran PF00005.22 EIM90451.1 - 1.2e-51 174.5 0.0 4.9e-28 98.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM90451.1 - 4.4e-50 170.6 35.2 3.2e-27 95.6 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EIM90451.1 - 4.2e-10 40.0 0.1 0.17 11.8 0.1 4.6 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EIM90451.1 - 5.6e-08 32.2 0.5 0.0029 16.8 0.1 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM90451.1 - 1e-07 31.5 0.0 0.005 16.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIM90451.1 - 1.5e-06 27.6 1.2 0.056 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIM90451.1 - 3.6e-05 23.6 2.5 0.12 12.3 0.1 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EIM90451.1 - 0.00069 18.8 1.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIM90451.1 - 0.0015 19.3 1.1 1.2 9.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIM90451.1 - 0.0015 19.0 1.8 1.4 9.4 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein ATP_bind_1 PF03029.12 EIM90451.1 - 0.003 17.1 0.8 0.72 9.3 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EIM90451.1 - 0.0036 17.1 1.1 1.6 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EIM90451.1 - 0.0048 16.6 1.3 1.7 8.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIM90451.1 - 0.0053 16.7 4.8 0.54 10.2 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EIM90451.1 - 0.009 15.4 3.9 0.67 9.3 0.3 2.6 3 0 0 3 3 2 2 AAA-like domain NACHT PF05729.7 EIM90451.1 - 0.012 15.2 0.9 0.63 9.6 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EIM90451.1 - 0.02 14.6 0.1 0.81 9.3 0.0 3.2 3 1 0 3 3 3 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EIM90451.1 - 0.033 13.6 0.2 7.1 6.0 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EIM90451.1 - 0.042 12.9 0.3 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 EIM90451.1 - 0.044 14.1 7.6 1.5 9.1 0.0 3.3 2 1 1 3 3 2 0 AAA domain T2SE PF00437.15 EIM90451.1 - 0.051 12.4 0.0 2.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EIM90451.1 - 0.058 12.1 1.3 1.8 7.2 0.2 2.3 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 EIM90451.1 - 0.068 12.9 2.2 0.55 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EIM90451.1 - 0.093 12.8 4.7 2.6 8.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EIM90451.1 - 0.097 12.1 3.5 1.1 8.6 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EIM90451.1 - 0.16 11.5 1.3 0.91 9.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EIM90451.1 - 0.17 11.4 3.0 4.5 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EIM90451.1 - 0.17 11.3 1.8 8.5 5.8 0.2 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EIM90451.1 - 0.21 11.7 0.1 32 4.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_13 PF13166.1 EIM90451.1 - 0.27 9.6 1.3 0.58 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIM90451.1 - 0.54 10.0 7.0 3.1 7.5 0.1 2.9 3 0 0 3 3 3 0 Dynamin family ABC_ATPase PF09818.4 EIM90451.1 - 0.84 8.1 4.3 6.4 5.2 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class WD40 PF00400.27 EIM90453.1 - 4.7e-35 118.2 17.0 6.4e-11 41.7 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat DNA_pol_E_B PF04042.11 EIM90454.1 - 1.1e-36 126.1 0.2 3.6e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Copper-bind PF00127.15 EIM90455.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Hid1 PF12722.2 EIM90456.1 - 2.7e-151 505.2 0.0 1.5e-150 502.7 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EIM90456.1 - 3.6e-57 193.9 0.0 5e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF3554 PF12074.3 EIM90457.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) RVT_3 PF13456.1 EIM90459.1 - 0.0036 17.0 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like Phage_integrase PF00589.17 EIM90460.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.8 1 1 0 1 1 1 0 Phage integrase family RVT_1 PF00078.22 EIM90461.1 - 4.6e-07 29.4 0.0 1.3e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_4 PF06347.8 EIM90461.1 - 0.084 12.4 0.1 0.084 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain RNase_H PF00075.19 EIM90462.1 - 1.3e-22 80.4 0.0 1.5e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 RNase H Rad51 PF08423.6 EIM90463.1 - 0.00044 19.2 0.1 0.00067 18.6 0.1 1.3 1 0 0 1 1 1 1 Rad51 Atg8 PF02991.11 EIM90464.1 - 9.1e-52 173.3 0.2 1.1e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EIM90464.1 - 4.6e-07 29.9 0.0 5.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.12 EIM90464.1 - 0.1 12.1 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Variant SH3 domain BBS2_C PF14782.1 EIM90465.1 - 0.0076 14.8 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BRE1 PF08647.6 EIM90465.1 - 0.01 15.7 2.4 0.018 14.9 1.6 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Pol_alpha_B_N PF08418.5 EIM90465.1 - 2.1 7.8 8.0 0.063 12.8 1.0 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal UCR_14kD PF02271.11 EIM90466.1 - 7.6e-37 125.2 0.2 8.7e-37 125.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.14 EIM90467.1 - 4.6e-55 185.1 0.0 5.2e-55 184.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EIM90467.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Pkinase_Tyr PF07714.12 EIM90468.1 - 1.2e-36 126.1 0.0 2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM90468.1 - 3.5e-34 118.1 0.0 6.3e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 EIM90468.1 - 6.6e-31 107.4 0.2 1.4e-30 106.4 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIM90468.1 - 8e-12 45.1 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif APH PF01636.18 EIM90468.1 - 0.015 14.9 4.8 0.033 13.9 0.2 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM90468.1 - 0.077 12.0 0.1 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cmc1 PF08583.5 EIM90469.1 - 9.1e-10 38.1 1.7 1.1e-09 37.9 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like OB_RNB PF08206.6 EIM90469.1 - 0.15 11.5 0.1 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain NDUF_B7 PF05676.8 EIM90469.1 - 0.23 10.9 1.2 0.21 10.9 0.2 1.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Transketolase_N PF00456.16 EIM90470.1 - 2.6e-149 496.5 0.0 3.5e-149 496.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIM90470.1 - 5.8e-42 143.1 0.0 1.9e-41 141.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIM90470.1 - 3.6e-13 49.5 0.0 7.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EIM90470.1 - 1.3e-07 30.8 0.0 1.1e-06 27.7 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase UvrD-helicase PF00580.16 EIM90471.1 - 3.8e-09 36.2 0.0 0.00082 18.7 0.0 2.6 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EIM90471.1 - 7e-08 32.5 0.0 4.7e-07 29.8 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.1 EIM90471.1 - 8.5e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM90471.1 - 0.00014 21.5 1.3 0.0003 20.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD_C PF13361.1 EIM90471.1 - 0.0006 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EIM90471.1 - 0.00088 18.8 0.2 0.24 10.8 0.0 3.3 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIM90471.1 - 0.0022 17.5 0.2 0.0098 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EIM90471.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DnaB_C PF03796.10 EIM90471.1 - 0.017 13.9 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 EIM90471.1 - 0.049 12.7 0.1 0.049 12.7 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EIM90471.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EIM90472.1 - 8e-34 116.8 36.9 8e-34 116.8 25.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EIM90472.1 - 0.27 10.7 3.6 3.7 7.1 0.0 3.0 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC WD40 PF00400.27 EIM90473.1 - 2.6e-61 201.4 30.4 2.3e-10 39.9 0.2 8.6 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIM90473.1 - 4.9e-12 45.3 0.2 1.2e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIM90473.1 - 6.2e-11 41.1 11.6 0.018 13.1 0.2 6.1 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EIM90473.1 - 1.8e-10 40.1 0.2 4.2e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EIM90473.1 - 0.00088 19.0 0.2 9 6.1 0.0 4.9 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 EIM90475.1 - 3e-62 210.1 0.0 3.6e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90475.1 - 1.6e-25 89.7 0.0 2.1e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM90475.1 - 3e-05 23.1 0.0 0.00025 20.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIM90475.1 - 0.00015 21.6 0.1 0.021 14.5 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM90475.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NDUF_B12 PF08122.7 EIM90478.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family 2TM PF13239.1 EIM90478.1 - 8.5 6.5 6.3 5.7 7.0 1.9 2.1 1 1 0 2 2 2 0 2TM domain Glyco_hydro_63 PF03200.11 EIM90479.1 - 1.3e-226 754.1 0.0 9.7e-226 751.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 EIM90479.1 - 6.2e-05 21.8 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 EIM90479.1 - 0.00026 19.7 0.1 0.00045 18.9 0.1 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 EIM90479.1 - 0.031 12.4 0.0 0.05 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase RNB PF00773.14 EIM90480.1 - 1.8e-92 310.1 0.0 2.7e-92 309.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EIM90480.1 - 4.5e-10 39.7 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EIM90480.1 - 0.88 9.1 3.1 1.8 8.1 0.1 2.7 3 0 0 3 3 3 0 Ribonuclease B OB domain HAD_2 PF13419.1 EIM90481.1 - 3.3e-29 102.3 0.0 4.3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM90481.1 - 6.9e-08 32.0 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM90481.1 - 9.9e-06 26.1 0.0 0.00094 19.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pyridoxal_deC PF00282.14 EIM90482.1 - 6.9e-59 199.1 0.0 9.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIM90482.1 - 2.6e-06 26.4 0.0 3.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DNA_pol_A_exo1 PF01612.15 EIM90483.1 - 5.5e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.15 EIM90484.1 - 8.7e-08 31.8 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease adh_short PF00106.20 EIM90485.1 - 6.3e-22 78.2 0.3 8.4e-22 77.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90485.1 - 1.7e-21 77.0 0.0 2.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90485.1 - 6.6e-11 42.1 0.1 9.9e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain PIN_4 PF13638.1 EIM90486.1 - 4.4e-19 68.9 0.2 4.4e-19 68.9 0.1 1.9 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 EIM90486.1 - 3.3e-11 42.9 0.0 4.4e-10 39.2 0.0 2.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF2346 PF09803.4 EIM90487.1 - 1.1e-08 34.7 0.7 1.9e-08 34.0 0.5 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) peroxidase PF00141.18 EIM90488.1 - 3.8e-21 75.6 0.0 6.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase BTP PF05232.7 EIM90488.1 - 0.12 12.1 0.9 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DNA_pol_A_exo1 PF01612.15 EIM90489.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease OTT_1508_deam PF14441.1 EIM90490.1 - 1.1e-05 25.3 0.1 3.4e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase PALP PF00291.20 EIM90491.1 - 2.7e-52 177.9 0.0 3.3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cyt-b5 PF00173.23 EIM90492.1 - 2.9e-23 81.4 0.1 6.2e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIM90492.1 - 1.5e-07 31.8 19.8 2.7e-07 30.9 12.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2502 PF10697.4 EIM90494.1 - 0.033 14.2 1.4 0.041 13.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Amidohydro_2 PF04909.9 EIM90495.1 - 3.7e-27 95.5 0.0 7.9e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EIM90495.1 - 0.0026 17.0 0.0 0.015 14.5 0.0 2.1 2 1 0 2 2 2 1 TatD related DNase BolA PF01722.13 EIM90496.1 - 2.3e-23 81.9 0.0 2.8e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Flt3_lig PF02947.9 EIM90496.1 - 0.077 12.8 0.0 0.085 12.7 0.0 1.0 1 0 0 1 1 1 0 flt3 ligand DUF4200 PF13863.1 EIM90497.1 - 0.011 15.6 0.2 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Glyco_hydro_31 PF01055.21 EIM90498.1 - 5e-121 404.6 0.1 6.7e-121 404.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM90498.1 - 6.4e-18 64.3 0.3 5.1e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like WD40 PF00400.27 EIM90499.1 - 1.3e-26 91.4 5.4 6.8e-09 35.2 0.0 5.2 4 1 0 4 4 4 4 WD domain, G-beta repeat PBP_sp32 PF07222.7 EIM90499.1 - 0.8 8.8 5.8 1.3 8.0 4.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EIM90499.1 - 0.99 7.3 9.4 1.2 7.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EIM90499.1 - 1 7.9 5.0 1.5 7.3 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 EIM90499.1 - 3.4 6.8 9.9 4.5 6.4 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein DDHD PF02862.12 EIM90499.1 - 5.5 6.7 5.9 1.2 8.8 0.7 2.2 2 1 0 2 2 2 0 DDHD domain Lamp PF01299.12 EIM90500.1 - 3.3 6.7 9.6 4.9 6.2 6.7 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MRP-L27 PF09809.4 EIM90501.1 - 1.7e-10 40.5 0.4 2.3e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 AAA_22 PF13401.1 EIM90503.1 - 0.0021 18.1 0.3 2.8 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM90503.1 - 0.025 14.3 0.3 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain F-box-like PF12937.2 EIM90506.1 - 2.5e-07 30.3 0.2 1.2e-06 28.1 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM90506.1 - 0.022 14.3 1.4 0.1 12.2 0.1 2.6 2 0 0 2 2 2 0 F-box domain CBF PF03914.12 EIM90507.1 - 1e-42 145.4 1.0 2.5e-42 144.0 0.7 1.7 1 0 0 1 1 1 1 CBF/Mak21 family HEAT PF02985.17 EIM90507.1 - 0.024 14.6 0.0 10 6.5 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat COQ7 PF03232.8 EIM90509.1 - 5.1e-68 227.8 0.3 6.2e-68 227.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.1 EIM90509.1 - 0.092 12.6 0.1 7.7 6.4 0.1 2.2 1 1 1 2 2 2 0 Ferritin-like domain G-patch PF01585.18 EIM90511.1 - 3.9e-13 48.9 1.8 1.1e-12 47.5 1.3 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EIM90511.1 - 1.5e-11 43.7 0.1 1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM90511.1 - 4e-11 42.7 0.0 3.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EIM90511.1 - 2.6e-05 23.9 0.4 2.6e-05 23.9 0.3 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EIM90511.1 - 8.9e-05 22.2 0.1 0.088 12.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ROS_MUCR PF05443.6 EIM90511.1 - 0.0058 16.4 0.4 0.017 14.8 0.1 1.9 1 1 0 1 1 1 1 ROS/MUCR transcriptional regulator protein zf-C2H2_jaz PF12171.3 EIM90511.1 - 0.0068 16.5 1.2 0.0068 16.5 0.8 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIM90511.1 - 0.037 14.1 0.2 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIM90511.1 - 0.13 12.6 0.8 0.25 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM90512.1 - 1.7e-05 24.8 8.0 0.06 13.7 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM90512.1 - 0.019 15.2 4.6 0.91 9.9 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM90512.1 - 0.063 13.6 1.1 0.51 10.7 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain FH2 PF02181.18 EIM90513.1 - 9.8e-78 261.6 2.1 9.8e-78 261.6 1.5 2.5 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIM90513.1 - 3.3e-35 121.1 0.0 9.3e-35 119.6 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIM90513.1 - 4.7e-32 111.0 0.5 4.7e-32 111.0 0.3 2.1 2 0 0 2 2 2 1 Diaphanous FH3 Domain SPOUT_MTase_2 PF14419.1 EIM90513.1 - 0.18 11.0 0.1 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP F-box-like PF12937.2 EIM90514.1 - 5.3e-06 26.0 6.6 5.3e-06 26.0 4.5 3.0 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EIM90514.1 - 0.0018 17.8 0.2 2.3 7.9 0.0 3.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM90514.1 - 0.095 12.8 0.1 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PAP2 PF01569.16 EIM90515.1 - 5e-20 71.4 4.7 5e-20 71.4 3.2 1.9 2 1 0 2 2 2 1 PAP2 superfamily ATP_synt_H PF05493.8 EIM90515.1 - 0.23 11.5 2.5 0.58 10.2 1.7 1.7 1 0 0 1 1 1 0 ATP synthase subunit H CRM1_C PF08767.6 EIM90517.1 - 6.4e-100 334.1 4.7 9.6e-98 327.0 0.0 3.7 4 0 0 4 4 4 2 CRM1 C terminal Xpo1 PF08389.7 EIM90517.1 - 3.7e-36 124.2 4.8 3.7e-36 124.2 3.3 3.9 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIM90517.1 - 2.3e-10 40.2 0.1 3.1e-09 36.6 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EIM90517.1 - 0.017 15.0 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Med10 PF09748.4 EIM90518.1 - 5.2e-17 61.8 0.0 6.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FUSC_2 PF13515.1 EIM90519.1 - 6.8e-15 55.1 14.4 6.8e-15 55.1 10.0 2.7 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIM90519.1 - 3.5e-09 35.6 11.5 9.1e-09 34.3 7.9 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.3 EIM90519.1 - 4.5e-06 25.5 13.8 0.0055 15.4 8.1 3.1 2 1 1 3 3 3 2 Aluminium activated malate transporter DUF2422 PF10337.4 EIM90519.1 - 0.0028 16.4 13.4 0.42 9.3 0.8 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) DUF939 PF06081.6 EIM90519.1 - 0.0061 16.4 7.4 0.0061 16.4 5.1 2.6 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF939) Fusion_gly PF00523.13 EIM90519.1 - 0.078 11.0 0.2 0.12 10.3 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Myosin_head PF00063.16 EIM90520.1 - 9.7e-239 793.9 0.0 1.5e-238 793.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EIM90520.1 - 4.8e-34 116.3 2.2 1.8e-33 114.5 1.5 2.1 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EIM90520.1 - 3e-15 54.3 34.1 0.0029 17.1 1.0 7.1 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EIM90520.1 - 0.0059 16.7 0.0 0.065 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIM90520.1 - 0.11 12.8 2.4 0.95 9.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Myosin_N PF02736.14 EIM90520.1 - 0.16 11.6 1.4 0.36 10.5 1.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF972 PF06156.8 EIM90520.1 - 6.6 7.1 9.2 33 4.8 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) zf-AN1 PF01428.11 EIM90521.1 - 6.2e-18 64.4 13.0 4e-10 39.3 2.7 2.5 2 1 0 2 2 2 2 AN1-like Zinc finger Gpi1 PF05024.10 EIM90522.1 - 1.1e-41 142.6 9.8 1.8e-41 141.9 6.8 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Snf7 PF03357.16 EIM90523.1 - 2.9e-41 140.7 20.3 2.9e-41 140.7 14.1 1.6 2 0 0 2 2 2 1 Snf7 Glyco_hydro_17 PF00332.13 EIM90523.1 - 0.17 10.9 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 YlqD PF11068.3 EIM90523.1 - 1.1 9.2 16.0 2.7 8.0 4.7 2.2 1 1 1 2 2 2 0 YlqD protein Resolvase PF00239.16 EIM90523.1 - 1.9 8.3 11.8 0.85 9.4 4.0 2.2 1 1 1 2 2 2 0 Resolvase, N terminal domain V_ATPase_I PF01496.14 EIM90523.1 - 2.2 6.0 8.1 4 5.1 5.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.4 EIM90523.1 - 9.5 6.4 9.4 4.4 7.5 0.3 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG4 PF08318.7 EIM90524.1 - 2.2e-57 194.2 0.0 3.6e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein FlgN PF05130.7 EIM90524.1 - 0.27 11.4 4.7 0.4 10.9 2.2 2.0 2 0 0 2 2 2 0 FlgN protein IncA PF04156.9 EIM90524.1 - 0.45 10.0 5.8 0.34 10.5 2.6 1.8 2 0 0 2 2 2 0 IncA protein Cellulase PF00150.13 EIM90525.1 - 5.7e-14 51.9 0.6 1.9e-13 50.2 0.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 EIM90525.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Epimerase PF01370.16 EIM90526.1 - 4e-17 62.4 0.0 6.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM90526.1 - 1.3e-06 28.5 0.1 4.5e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM90526.1 - 2.1e-06 26.8 0.0 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EIM90526.1 - 3.7e-06 25.8 0.0 1.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIM90526.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.20 EIM90527.1 - 2.7e-55 187.3 0.1 3.8e-55 186.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90527.1 - 1.5e-19 70.0 0.2 2.9e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90527.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM90527.1 - 0.0037 16.6 0.9 0.008 15.5 0.6 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIM90527.1 - 0.088 12.3 1.7 0.17 11.4 1.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DEAD PF00270.24 EIM90529.1 - 2.3e-23 82.5 0.0 7e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM90529.1 - 5.2e-17 61.4 0.1 3.8e-16 58.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 EIM90529.1 - 1.8e-10 40.4 0.0 4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 EIM90529.1 - 0.00029 20.7 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIM90529.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain HEM4 PF02602.10 EIM90529.1 - 0.013 14.7 0.0 19 4.4 0.0 3.3 3 0 0 3 3 3 0 Uroporphyrinogen-III synthase HemD DEAD PF00270.24 EIM90530.1 - 1e-42 145.4 0.0 1.1e-41 142.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM90530.1 - 9.1e-23 79.9 0.0 2.7e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM90530.1 - 0.00011 22.1 0.2 0.033 14.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIM90530.1 - 0.0028 16.1 0.0 0.12 10.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) DUF4137 PF13593.1 EIM90530.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) CMS1 PF14617.1 EIM90530.1 - 0.25 10.4 7.4 1.4 7.9 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ycf1 PF05758.7 EIM90530.1 - 1 7.0 6.3 1.4 6.5 4.3 1.2 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 EIM90530.1 - 6 6.6 14.5 12 5.6 10.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GalP_UDP_transf PF01087.17 EIM90531.1 - 5.4e-60 202.5 0.0 1.5e-59 201.1 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EIM90531.1 - 4.7e-47 159.6 0.0 2.5e-46 157.2 0.0 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EIM90531.1 - 0.0026 18.2 0.9 0.0097 16.4 0.1 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EIM90531.1 - 0.0043 17.2 0.5 0.029 14.5 0.0 2.3 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding 6PF2K PF01591.13 EIM90533.1 - 6.3e-68 228.1 0.1 8.4e-68 227.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIM90533.1 - 1.8e-31 109.3 0.0 4.5e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIM90533.1 - 3.2e-08 33.5 0.1 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIM90533.1 - 0.00027 21.7 0.1 0.0012 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM90533.1 - 0.013 14.5 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EIM90533.1 - 0.019 14.2 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_hydro_26 PF02156.10 EIM90533.1 - 0.055 12.9 0.1 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 GBP PF02263.14 EIM90533.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Glyco_transf_8 PF01501.15 EIM90534.1 - 0.0037 16.6 0.0 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 DUF616 PF04765.8 EIM90534.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF616) PNK3P PF08645.6 EIM90535.1 - 4e-46 156.3 0.0 6.4e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EIM90535.1 - 2.9e-25 88.8 0.0 1.9e-24 86.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain LNS2 PF08235.8 EIM90535.1 - 3.6e-06 26.6 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Zeta_toxin PF06414.7 EIM90535.1 - 0.007 15.4 0.0 3.3 6.7 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin Hydrolase_6 PF13344.1 EIM90535.1 - 0.013 15.4 0.1 0.24 11.3 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_25 PF13481.1 EIM90535.1 - 0.022 14.1 0.1 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIM90535.1 - 0.041 13.0 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EIM90535.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sel1 PF08238.7 EIM90536.1 - 6.3e-47 156.9 29.5 8.5e-09 35.7 0.0 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_14 PF13428.1 EIM90536.1 - 1 10.2 18.6 0.72 10.6 0.2 6.5 6 2 2 8 8 8 0 Tetratricopeptide repeat PHD PF00628.24 EIM90537.1 - 6.9e-08 32.0 8.8 1.2e-07 31.2 6.1 1.4 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.17 EIM90537.1 - 1.7e-07 31.4 0.2 1.8e-06 28.1 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIM90537.1 - 4e-05 23.2 0.3 0.00014 21.4 0.0 2.2 2 1 0 2 2 2 1 Cupin-like domain DUF2387 PF09526.5 EIM90537.1 - 0.13 12.2 1.5 0.39 10.6 1.1 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) PHD_2 PF13831.1 EIM90537.1 - 2.9 7.3 5.3 5.7 6.3 3.7 1.5 1 0 0 1 1 1 0 PHD-finger Ras PF00071.17 EIM90538.1 - 7.6e-53 178.2 0.0 9e-53 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM90538.1 - 1.4e-16 61.0 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM90538.1 - 5.2e-07 29.0 0.0 1.2e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM90538.1 - 0.0074 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EIM90538.1 - 0.073 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EIM90538.1 - 0.12 11.8 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EIM90538.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1090 PF06476.7 EIM90539.1 - 7.2 6.3 14.0 2.8 7.6 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) PGK PF00162.14 EIM90540.1 - 1.5e-148 494.4 0.1 1.7e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF1311 PF07007.7 EIM90544.1 - 0.0028 17.7 0.4 0.0089 16.0 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1311) DDE_3 PF13358.1 EIM90545.1 - 4.6e-10 39.4 0.0 6.6e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Metallothio_Euk PF12749.2 EIM90547.1 - 0.34 10.9 9.0 0.41 10.7 6.2 1.1 1 0 0 1 1 1 0 Eukaryotic metallothionein HTH_Tnp_Tc5 PF03221.11 EIM90549.1 - 6e-06 25.9 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EIM90550.1 - 4.9e-26 91.2 0.0 1.7e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM90550.1 - 1.7e-07 31.0 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Helicase_C PF00271.26 EIM90552.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop14 PF04147.7 EIM90552.1 - 0.088 10.7 13.4 0.086 10.7 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EIM90552.1 - 2.4 6.5 16.0 2.8 6.2 11.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EIM90552.1 - 5.9 4.7 11.5 6.4 4.6 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EIM90552.1 - 7.7 5.6 11.7 10 5.2 8.1 1.3 1 0 0 1 1 1 0 NOA36 protein CHORD PF04968.7 EIM90554.1 - 4.7e-47 158.1 13.0 3.1e-24 84.9 2.7 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 EIM90554.1 - 4.4e-13 49.5 0.0 7.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 CS domain Rieske PF00355.21 EIM90554.1 - 0.023 14.2 5.8 0.8 9.3 0.2 2.5 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Ost4 PF10215.4 EIM90554.1 - 0.15 11.5 0.3 0.27 10.7 0.2 1.3 1 0 0 1 1 1 0 Oligosaccaryltransferase Cu-oxidase_3 PF07732.10 EIM90555.1 - 1.2e-40 137.8 1.7 1.2e-40 137.8 1.2 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM90555.1 - 5.5e-35 119.8 6.5 4.7e-30 103.8 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EIM90555.1 - 4.8e-33 114.3 0.1 1.3e-32 112.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Glyco_tranf_2_3 PF13641.1 EIM90557.1 - 1.3e-11 44.7 0.4 6.1e-07 29.4 0.3 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EIM90557.1 - 2.3e-10 39.5 0.0 4.1e-08 32.0 0.0 2.9 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIM90557.1 - 3.3e-08 33.4 6.0 3.3e-08 33.4 4.2 2.6 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIM90557.1 - 0.0009 18.5 0.2 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIM90557.1 - 0.0011 18.6 0.0 0.35 10.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF218 PF02698.12 EIM90559.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Uricase PF01014.13 EIM90560.1 - 3.1e-59 198.9 0.4 1.5e-34 119.0 1.0 2.4 2 1 0 2 2 2 2 Uricase DUF2066 PF09839.4 EIM90560.1 - 0.063 12.3 1.0 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) ATP-synt_G PF04718.10 EIM90561.1 - 1.3e-18 67.5 2.6 6e-18 65.3 0.2 2.3 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit Apolipoprotein PF01442.13 EIM90561.1 - 0.023 14.2 1.0 0.027 13.9 0.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EIM90561.1 - 0.055 13.8 0.2 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.13 EIM90561.1 - 0.4 10.4 9.6 0.96 9.2 6.0 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Ifi-6-16 PF06140.8 EIM90562.1 - 0.044 13.5 1.0 0.084 12.6 0.7 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family FAD_binding_3 PF01494.14 EIM90564.1 - 9.3e-72 242.0 0.0 1.2e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIM90564.1 - 0.0015 18.4 0.0 0.0061 16.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM90564.1 - 0.0039 15.7 0.1 0.57 8.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EIM90564.1 - 0.016 14.1 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM90564.1 - 0.036 14.1 0.1 0.99 9.4 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM90564.1 - 0.068 12.0 0.2 0.43 9.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EIM90564.1 - 0.071 13.5 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM90564.1 - 0.083 11.7 0.1 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.20 EIM90565.1 - 5.8e-27 94.6 0.0 7.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90565.1 - 2.1e-13 50.6 0.0 2.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90565.1 - 2.7e-09 36.9 0.0 7.3e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM90565.1 - 0.00023 20.6 0.0 0.00064 19.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIM90565.1 - 0.00031 19.7 0.0 0.00042 19.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIM90565.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF2202 PF09968.4 EIM90566.1 - 0.0034 17.0 0.2 0.0054 16.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein domain (DUF2202) CagX PF03524.10 EIM90566.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 1 0 1 1 1 0 Conjugal transfer protein adh_short PF00106.20 EIM90567.1 - 2.9e-24 85.8 0.0 4.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90567.1 - 6.7e-13 48.9 0.0 9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90567.1 - 5.2e-09 36.0 0.0 2.3e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM90567.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIM90567.1 - 0.065 12.1 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain zf-H2C2_2 PF13465.1 EIM90569.1 - 4.2e-08 33.0 9.4 7.8e-07 29.0 1.0 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM90569.1 - 7.4e-08 32.1 14.6 0.0014 18.8 2.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM90569.1 - 1.8e-07 31.0 15.7 0.0021 18.2 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EIM90569.1 - 0.00075 19.6 1.2 0.0017 18.5 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Zn_clus PF00172.13 EIM90569.1 - 0.25 11.2 17.7 0.015 15.1 8.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.7 EIM90571.1 - 2.6e-11 43.3 0.1 2.9e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EIM90571.1 - 2.2e-07 30.1 0.0 3.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EIM90571.1 - 0.0029 17.0 0.0 0.0068 15.8 0.0 1.7 1 1 1 2 2 2 1 Cupin domain Cupin_6 PF12852.2 EIM90571.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Cupin VWA_3 PF13768.1 EIM90572.1 - 1.8e-21 76.4 0.1 3.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIM90572.1 - 9.6e-14 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EIM90572.1 - 1.5e-12 47.9 0.1 3.4e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EIM90572.1 - 1.5e-11 43.9 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 EIM90572.1 - 7.4e-07 28.5 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EIM90572.1 - 6.2e-06 25.5 0.0 1.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EIM90572.1 - 8.4e-06 25.7 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF605 PF04652.11 EIM90572.1 - 0.13 11.6 5.6 0.22 10.9 3.9 1.3 1 0 0 1 1 1 0 Vta1 like Herpes_capsid PF06112.6 EIM90573.1 - 1.9 8.5 22.7 0.024 14.6 5.9 2.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ADH_zinc_N PF00107.21 EIM90574.1 - 1e-15 57.4 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM90574.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM90574.1 - 0.0031 18.4 0.0 0.0056 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiG_N PF11760.3 EIM90574.1 - 0.11 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal NmrA PF05368.8 EIM90576.1 - 5.9e-25 87.8 0.2 1.1e-24 87.0 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90576.1 - 1.5e-12 47.8 1.1 2e-12 47.4 0.8 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90576.1 - 3.6e-06 26.5 0.1 0.00014 21.4 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EIM90576.1 - 0.00069 19.4 0.3 0.0012 18.6 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIM90576.1 - 0.0034 17.7 1.1 0.0057 17.0 0.7 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EIM90576.1 - 0.0043 16.7 0.2 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM90576.1 - 0.006 16.5 0.7 0.019 14.8 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EIM90576.1 - 0.0086 14.8 0.1 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIM90576.1 - 0.098 12.9 0.5 0.25 11.6 0.4 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EIM90576.1 - 0.11 11.3 0.1 0.19 10.6 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 EIM90577.1 - 2.4e-69 234.0 0.0 1.8e-68 231.1 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EIM90578.1 - 3.3e-27 95.4 0.2 5.1e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90578.1 - 6.1e-25 88.3 0.1 7.2e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90578.1 - 2.4e-07 30.6 0.2 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM90579.1 - 2.2e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM90579.1 - 4.8e-07 29.8 0.0 7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM90579.1 - 0.011 15.4 0.1 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 KR domain IclR PF01614.13 EIM90579.1 - 0.13 12.0 0.1 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial transcriptional regulator MFS_1 PF07690.11 EIM90581.1 - 1.5e-36 125.8 37.5 1.5e-36 125.8 26.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM90581.1 - 1.1e-07 30.8 28.0 1.2e-06 27.3 19.4 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_18 PF00704.23 EIM90582.1 - 4.6e-08 32.8 1.6 7.8e-08 32.1 1.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 EIM90582.1 - 6.4e-08 32.0 6.1 6.4e-08 32.0 4.2 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain AMP-binding PF00501.23 EIM90583.1 - 4e-38 130.8 0.0 6.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Pex14_N PF04695.8 EIM90583.1 - 4.2 7.4 6.6 9.2 6.3 4.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NmrA PF05368.8 EIM90585.1 - 8.4e-25 87.3 0.2 2.6e-24 85.7 0.2 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90585.1 - 3.3e-12 46.7 0.4 6.7e-12 45.7 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90585.1 - 0.00013 21.5 0.1 0.009 15.4 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EIM90585.1 - 0.0043 17.4 1.0 0.0094 16.3 0.7 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EIM90585.1 - 0.0059 15.3 0.1 0.0086 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM90585.1 - 0.013 15.2 0.2 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EIM90585.1 - 0.037 13.9 0.2 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ubie_methyltran PF01209.13 EIM90585.1 - 0.078 12.0 0.0 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DapB_N PF01113.15 EIM90585.1 - 0.085 12.7 0.3 0.17 11.7 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-MYND PF01753.13 EIM90586.1 - 2e-10 40.3 11.8 4.1e-10 39.3 8.2 1.6 1 0 0 1 1 1 1 MYND finger DUF3494 PF11999.3 EIM90588.1 - 2.1e-51 174.4 12.9 2.5e-51 174.2 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Lysis_col PF02402.11 EIM90588.1 - 5 6.8 8.0 2.3 7.8 0.1 3.3 2 1 1 3 3 3 0 Lysis protein NmrA PF05368.8 EIM90589.1 - 2.3e-24 85.9 0.5 8.8e-24 84.0 0.4 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90589.1 - 3.8e-14 53.0 0.8 8e-14 52.0 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90589.1 - 1.1e-06 28.2 0.1 6.9e-05 22.4 0.2 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90589.1 - 5.7e-05 21.9 0.2 8.5e-05 21.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM90589.1 - 0.00073 19.2 0.6 0.0015 18.2 0.2 1.7 2 0 0 2 2 2 1 KR domain DapB_N PF01113.15 EIM90589.1 - 0.0046 16.8 0.2 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EIM90589.1 - 0.0048 16.8 0.7 0.028 14.3 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EIM90589.1 - 0.0098 14.9 0.6 0.013 14.5 0.4 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EIM90589.1 - 0.023 15.1 0.4 0.06 13.7 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EIM90589.1 - 0.056 13.9 0.2 0.42 11.1 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EIM90589.1 - 0.073 13.3 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Flagellar_rod PF05149.7 EIM90589.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein NmrA PF05368.8 EIM90591.1 - 4.1e-22 78.5 0.1 1.9e-21 76.3 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90591.1 - 6.1e-14 52.4 0.1 2.1e-13 50.6 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90591.1 - 0.0028 17.1 0.0 0.055 12.9 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90591.1 - 0.0061 15.2 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM90591.1 - 0.041 13.5 0.1 0.15 11.6 0.0 1.9 2 1 0 2 2 2 0 KR domain DapB_N PF01113.15 EIM90591.1 - 0.065 13.1 0.1 0.18 11.7 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Apolipoprotein PF01442.13 EIM90592.1 - 0.036 13.5 11.2 0.77 9.2 1.9 3.8 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain ZZ PF00569.12 EIM90592.1 - 0.8 9.2 14.8 1.2 8.7 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type C1_1 PF00130.17 EIM90592.1 - 3.6 7.3 13.8 0.26 11.0 3.1 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 EIM90593.1 - 1.7e-20 73.2 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90593.1 - 4.8e-07 29.1 0.0 7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90593.1 - 2.3e-05 24.2 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM90593.1 - 0.018 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIM90593.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIM90594.1 - 1.4e-13 50.5 0.0 2.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF605 PF04652.11 EIM90595.1 - 0.047 13.0 12.8 0.058 12.7 8.9 1.1 1 0 0 1 1 1 0 Vta1 like MgtE PF01769.11 EIM90595.1 - 0.18 12.1 9.4 0.044 14.0 1.3 2.6 2 1 0 2 2 2 0 Divalent cation transporter DUF4131 PF13567.1 EIM90595.1 - 5 6.5 10.0 6.9 6.0 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Lipase_3 PF01764.20 EIM90596.1 - 1.4e-31 108.9 0.0 1.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EIM90596.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 Cutinase DUF2048 PF09752.4 EIM90596.1 - 0.05 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Chromo_shadow PF01393.14 EIM90596.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain NmrA PF05368.8 EIM90597.1 - 6.5e-25 87.7 1.0 2.5e-24 85.8 0.7 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90597.1 - 3.7e-13 49.8 1.6 8.4e-13 48.7 1.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90597.1 - 7.1e-07 28.8 0.0 2.4e-05 23.8 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90597.1 - 6.2e-05 21.8 0.2 9.4e-05 21.2 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM90597.1 - 0.00061 19.5 0.2 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EIM90597.1 - 0.008 16.5 0.5 0.025 15.0 0.3 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIM90597.1 - 0.012 15.4 0.9 0.049 13.5 0.3 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 EIM90597.1 - 0.026 14.4 0.3 0.026 14.4 0.2 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EIM90597.1 - 0.043 12.7 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EIM90597.1 - 0.065 12.1 0.2 0.14 11.0 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EIM90597.1 - 0.072 13.3 0.6 0.17 12.1 0.3 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 EIM90598.1 - 5.7e-43 146.9 0.0 7.6e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM90598.1 - 2.3e-05 23.3 0.8 4.8e-05 22.2 0.0 1.8 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM90598.1 - 9.3e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EIM90598.1 - 0.0032 16.1 0.1 0.0063 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) NmrA PF05368.8 EIM90599.1 - 4.3e-22 78.5 0.0 1.7e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM90599.1 - 2.1e-12 47.3 0.1 6.6e-12 45.7 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM90599.1 - 0.00015 21.3 0.1 0.0078 15.6 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90599.1 - 0.00046 18.9 0.0 0.00065 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIM90599.1 - 0.02 15.2 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIM90599.1 - 0.12 12.0 0.2 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 EIM90599.1 - 0.15 10.9 0.1 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-MYND PF01753.13 EIM90600.1 - 2e-10 40.3 12.4 3.4e-10 39.6 8.6 1.4 1 0 0 1 1 1 1 MYND finger Pho88 PF10032.4 EIM90602.1 - 7.4e-72 240.6 0.0 8.2e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) MTP18 PF10558.4 EIM90602.1 - 0.078 12.8 0.3 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) PH PF00169.24 EIM90603.1 - 0.00062 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Carbpep_Y_N PF05388.6 EIM90603.1 - 0.019 15.1 1.0 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide UPF0086 PF01868.11 EIM90604.1 - 4.5e-21 74.2 0.0 8.3e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Methyltransf_2 PF00891.13 EIM90605.1 - 3.7e-30 104.8 0.0 5.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIM90605.1 - 3.1e-07 30.2 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90605.1 - 2.6e-05 24.7 0.0 5.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90605.1 - 0.00015 21.4 0.0 0.00038 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM90605.1 - 0.00033 21.0 0.0 0.00067 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 EIM90606.1 - 7.8e-60 202.7 0.0 5.2e-59 200.0 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIM90606.1 - 5.7e-24 84.6 0.0 8.5e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EIM90606.1 - 1.6e-05 23.9 2.0 2.5e-05 23.2 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM90606.1 - 3e-05 23.9 2.1 3.5e-05 23.7 0.1 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIM90606.1 - 7.8e-05 21.3 0.8 0.00013 20.5 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIM90606.1 - 0.00018 20.6 0.1 0.00031 19.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIM90606.1 - 0.00053 18.9 0.8 0.00083 18.3 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM90606.1 - 0.001 18.0 1.2 0.0017 17.3 0.8 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM90606.1 - 0.001 19.1 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM90606.1 - 0.0012 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM90606.1 - 0.0046 15.8 0.9 0.0072 15.2 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIM90606.1 - 0.005 15.9 2.0 0.0072 15.4 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EIM90606.1 - 0.013 14.8 0.3 0.064 12.6 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EIM90606.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EIM90606.1 - 0.033 13.8 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIM90606.1 - 0.065 13.6 0.1 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 EIM90607.1 - 5.2e-37 127.3 0.0 9e-37 126.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIM90607.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90607.1 - 0.0025 18.4 0.0 0.0081 16.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM90607.1 - 0.0072 15.9 0.0 0.048 13.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM90607.1 - 0.017 15.5 0.0 0.096 13.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIM90607.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EIM90607.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EIM90608.1 - 3.9e-31 108.1 0.0 6.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RNA_pol_Rpc34 PF05158.7 EIM90608.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Cpn10 PF00166.16 EIM90610.1 - 8e-27 93.0 0.0 9.1e-27 92.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MAT_Alpha1 PF04769.7 EIM90611.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Cation_efflux PF01545.16 EIM90612.1 - 8.1e-37 126.8 8.9 1e-36 126.4 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family FAD_binding_3 PF01494.14 EIM90613.1 - 4.7e-16 58.7 0.0 2.2e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM90613.1 - 0.0023 16.8 0.1 0.0053 15.7 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM90613.1 - 0.0077 16.2 1.3 0.038 14.0 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM90613.1 - 0.023 14.4 0.2 0.081 12.6 0.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIM90613.1 - 0.14 10.7 0.9 0.23 10.0 0.6 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EIM90614.1 - 4.8e-15 55.4 0.0 8.6e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIM90614.1 - 1.2e-09 37.6 0.2 5.5e-08 32.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM90614.1 - 9.3e-08 31.9 0.2 1.9e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM90614.1 - 1.3e-05 24.2 0.4 2e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EIM90614.1 - 0.00028 20.1 0.1 0.049 12.6 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIM90614.1 - 0.00038 20.5 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM90614.1 - 0.00038 20.7 0.1 0.0026 18.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM90614.1 - 0.0005 20.0 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM90614.1 - 0.0024 16.4 0.1 0.0077 14.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIM90614.1 - 0.0035 16.4 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM90614.1 - 0.0045 16.0 0.2 0.0089 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EIM90614.1 - 0.018 14.8 0.4 0.042 13.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EIM90614.1 - 0.031 13.1 0.5 0.046 12.5 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIM90614.1 - 0.047 13.3 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIM90614.1 - 0.083 12.8 0.4 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding Glyco_transf_4 PF13439.1 EIM90614.1 - 0.084 12.5 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Methyltransf_2 PF00891.13 EIM90615.1 - 5.3e-19 68.3 0.0 8.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIM90615.1 - 0.013 15.2 0.0 0.051 13.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EIM90615.1 - 0.038 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Abhydrolase_9_N PF15420.1 EIM90616.1 - 0.058 13.1 0.1 0.062 13.0 0.1 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus UbiA PF01040.13 EIM90617.1 - 2.7e-22 79.2 18.2 3.4e-22 78.9 12.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_2 PF00891.13 EIM90618.1 - 1.4e-31 109.5 0.0 3e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM90618.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EIM90620.1 - 1.5e-35 122.5 0.0 5.3e-35 120.7 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM90620.1 - 0.00014 22.3 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM90620.1 - 0.0017 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM90620.1 - 0.028 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HTH_25 PF13413.1 EIM90623.1 - 0.065 12.8 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_2 PF00891.13 EIM90624.1 - 1.9e-23 82.9 0.0 1e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM90624.1 - 0.0014 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EIM90624.1 - 0.003 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.1 EIM90624.1 - 0.0049 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIM90624.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EIM90624.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EIM90624.1 - 0.021 14.1 0.0 0.092 12.0 0.0 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 EIM90624.1 - 0.051 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FliC_SP PF12613.3 EIM90624.1 - 0.15 12.2 1.2 0.43 10.8 0.9 1.8 1 0 0 1 1 1 0 Flagellin structural protein Methyltransf_31 PF13847.1 EIM90624.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SlyX PF04102.7 EIM90626.1 - 0.0018 18.5 0.3 0.0046 17.2 0.2 1.6 1 0 0 1 1 1 1 SlyX DUF1664 PF07889.7 EIM90626.1 - 0.04 13.7 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EIM90626.1 - 0.077 13.4 1.9 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EIM90626.1 - 0.14 12.4 0.1 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_C PF12498.3 EIM90626.1 - 1.7 9.8 9.2 2.9 9.1 0.3 3.2 3 0 0 3 3 3 0 Basic leucine-zipper C terminal zf-MYND PF01753.13 EIM90627.1 - 1.4e-11 44.0 16.0 2.3e-11 43.3 11.1 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EIM90627.1 - 0.32 10.3 3.6 0.64 9.3 2.5 1.5 1 0 0 1 1 1 0 Life-span regulatory factor SNARE_assoc PF09335.6 EIM90628.1 - 9.6e-17 61.3 9.1 9.6e-17 61.3 6.3 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3816 PF12822.2 EIM90628.1 - 1.5 8.7 14.7 3 7.7 9.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) zf-MYND PF01753.13 EIM90630.1 - 2e-08 33.9 18.8 3.7e-08 33.0 13.0 1.5 1 0 0 1 1 1 1 MYND finger FYVE_2 PF02318.11 EIM90630.1 - 0.094 12.6 5.6 0.17 11.7 3.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3989 PF13150.1 EIM90632.1 - 0.17 11.3 4.5 1.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Adeno_GP19K PF04881.8 EIM90633.1 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Adenovirus GP19K FixQ PF05545.6 EIM90635.1 - 0.061 12.9 0.6 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Vps53_N PF04100.7 EIM90637.1 - 0.073 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Pkinase PF00069.20 EIM90637.1 - 0.086 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Myc_target_1 PF15179.1 EIM90639.1 - 0.055 13.0 1.4 0.075 12.6 1.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 Pkinase PF00069.20 EIM90640.1 - 1.3e-58 198.1 0.0 1.7e-39 135.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90640.1 - 3.7e-26 91.7 0.3 3e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIM90640.1 - 0.00048 19.2 0.1 0.0011 18.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIM90640.1 - 0.0006 18.8 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM90640.1 - 0.016 14.9 0.1 0.076 12.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIM90640.1 - 0.034 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EIM90640.1 - 0.035 12.9 0.1 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Orbi_NS1 PF01718.11 EIM90640.1 - 0.041 11.9 0.1 0.059 11.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Pkinase_C PF00433.19 EIM90640.1 - 0.11 13.0 0.1 0.37 11.3 0.1 2.0 1 1 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.17 EIM90640.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EIM90641.1 - 0.00063 18.9 0.0 0.0023 17.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EIM90642.1 - 3.2e-05 23.1 0.0 0.00011 21.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EIM90642.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EIM90644.1 - 0.096 11.8 0.0 0.49 9.4 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EIM90645.1 - 5.5e-06 25.7 0.0 1.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90645.1 - 0.0077 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.2 EIM90646.1 - 2.8e-06 26.9 1.2 5.5e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like Paf1 PF03985.8 EIM90646.1 - 0.06 12.0 5.5 0.081 11.6 3.8 1.1 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.1 EIM90646.1 - 0.062 12.9 1.6 0.11 12.1 1.1 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EIM90646.1 - 1.9 7.4 10.7 2.8 6.8 7.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 EIM90646.1 - 2.7 7.5 15.2 4.1 6.9 10.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-MYND PF01753.13 EIM90647.1 - 2.5e-07 30.4 13.8 4.7e-07 29.5 9.6 1.4 1 0 0 1 1 1 1 MYND finger Beta-lactamase PF00144.19 EIM90648.1 - 1.6e-47 162.1 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.19 EIM90649.1 - 1.1e-48 166.0 0.1 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Glutaminase PF04960.10 EIM90649.1 - 0.014 14.4 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Glutaminase Methyltransf_2 PF00891.13 EIM90650.1 - 1.7e-32 112.5 0.0 4.2e-32 111.2 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIM90650.1 - 0.021 15.4 0.0 0.048 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Beta-lactamase PF00144.19 EIM90652.1 - 1.6e-49 168.7 0.0 2.4e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Siah-Interact_N PF09032.6 EIM90653.1 - 0.06 13.3 1.7 0.27 11.3 0.5 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal Cir_N PF10197.4 EIM90653.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.9 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR ADH_zinc_N PF00107.21 EIM90654.1 - 3.5e-29 100.9 0.1 5.1e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM90654.1 - 2e-13 51.3 0.0 3.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM90654.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIM90654.1 - 0.083 12.8 0.7 0.25 11.3 0.5 1.9 1 1 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 EIM90654.1 - 0.1 12.1 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.2 EIM90655.1 - 8.9e-08 31.7 0.4 8.9e-08 31.7 0.3 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIM90655.1 - 0.1 12.3 11.8 0.068 12.9 0.4 4.1 3 2 1 4 4 4 0 Leucine rich repeat F-box PF00646.28 EIM90655.1 - 6.9 6.4 8.5 14 5.5 0.8 3.3 3 0 0 3 3 3 0 F-box domain Methyltransf_2 PF00891.13 EIM90656.1 - 7.9e-25 87.4 0.0 2.1e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIM90656.1 - 6.1e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90656.1 - 0.00088 19.8 0.0 0.0028 18.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EIM90656.1 - 0.0022 17.7 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.7 EIM90656.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIM90656.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AhpC-TSA_2 PF13911.1 EIM90657.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIM90657.1 - 0.00031 20.4 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIM90657.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Redoxin COPIIcoated_ERV PF07970.7 EIM90658.1 - 2.8e-38 131.7 1.0 3.9e-38 131.2 0.7 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIM90658.1 - 2.7e-18 65.7 0.0 4.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3HC4_3 PF13920.1 EIM90662.1 - 2.7e-09 36.5 1.9 4.4e-09 35.8 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM90662.1 - 9.1e-09 35.2 4.6 1.4e-08 34.5 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM90662.1 - 1.9e-08 33.8 2.6 2.8e-08 33.3 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIM90662.1 - 3.6e-07 29.8 3.7 5.5e-07 29.3 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM90662.1 - 4.3e-07 29.4 2.1 7.7e-07 28.6 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIM90662.1 - 0.39 10.3 2.1 0.77 9.3 1.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIM90662.1 - 0.83 9.5 6.9 3.4 7.6 5.0 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Herpes_pp85 PF04637.7 EIM90662.1 - 1.5 7.0 4.6 2.8 6.1 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-RING_UBOX PF13445.1 EIM90662.1 - 2.6 7.8 9.2 0.37 10.5 2.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger GST_N_3 PF13417.1 EIM90667.1 - 4.1e-18 65.3 0.0 6.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM90667.1 - 8.4e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM90667.1 - 6.2e-14 51.7 0.0 1.3e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM90667.1 - 1.8e-11 43.8 0.0 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM90667.1 - 1.9e-10 40.5 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM90667.1 - 4.2e-05 23.9 0.0 6.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 EIM90667.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) GST_N PF02798.15 EIM90669.1 - 1.6e-16 60.1 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM90669.1 - 2e-16 59.7 0.1 4.3e-16 58.6 0.0 1.5 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM90669.1 - 6.2e-16 58.3 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM90669.1 - 3.2e-10 39.8 0.0 5.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM90669.1 - 1.6e-08 34.2 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM90669.1 - 7.5e-05 23.1 0.4 9.7e-05 22.7 0.3 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Transp_cyt_pur PF02133.10 EIM90670.1 - 1.7e-98 330.0 38.0 2.1e-98 329.7 26.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Hus1 PF04005.7 EIM90672.1 - 4.1e-77 259.0 0.3 4.6e-77 258.8 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Asp PF00026.18 EIM90673.1 - 5.4e-48 163.8 0.1 1.4e-47 162.4 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM90673.1 - 3.2e-05 23.9 0.1 0.00012 22.0 0.1 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Abhydrolase_6 PF12697.2 EIM90674.1 - 1.3e-24 87.3 0.3 1.7e-24 87.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM90674.1 - 1.9e-12 47.1 0.0 3.6e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM90674.1 - 1.1e-08 34.8 0.0 2.7e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIM90674.1 - 0.0072 15.7 0.0 0.023 14.1 0.0 1.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EIM90674.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Methyltransf_28 PF02636.12 EIM90675.1 - 2.3e-62 210.6 0.0 3e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Copine PF07002.11 EIM90675.1 - 0.17 11.6 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Copine Epimerase PF01370.16 EIM90676.1 - 1.5e-15 57.2 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EIM90676.1 - 0.00094 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EIM90676.1 - 0.001 18.0 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 EIM90676.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIM90676.1 - 0.0013 18.7 0.0 0.0062 16.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIM90676.1 - 0.0061 15.2 0.0 0.019 13.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIM90676.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TSGP1 PF07771.6 EIM90677.1 - 8.9 6.2 7.0 9.6 6.1 4.9 1.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 Glyco_hydro_81 PF03639.8 EIM90678.1 - 3.7e-76 256.6 2.2 3.7e-76 256.6 1.5 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 Fascin PF06268.8 EIM90678.1 - 4.8e-10 39.5 0.0 0.12 12.5 0.0 5.8 4 2 3 7 7 7 4 Fascin domain Peptidase_C25_C PF03785.9 EIM90678.1 - 0.068 12.9 1.0 15 5.4 0.0 3.9 4 0 0 4 4 4 0 Peptidase family C25, C terminal ig-like domain Abhydrolase_4 PF08386.5 EIM90679.1 - 1.3e-14 53.9 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EIM90679.1 - 5.2e-11 42.5 0.0 2.3e-10 40.4 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM90679.1 - 0.00039 20.3 0.3 0.0044 16.9 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF842 PF05811.8 EIM90679.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Abhydrolase_4 PF08386.5 EIM90680.1 - 3.1e-18 65.5 0.0 5.9e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EIM90680.1 - 1.8e-09 37.5 0.0 6.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM90680.1 - 2.8e-07 30.6 0.0 1.6e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM90680.1 - 0.079 12.7 0.0 1 9.1 0.0 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family eIF-6 PF01912.13 EIM90682.1 - 4.4e-85 283.7 0.2 4.4e-85 283.7 0.1 1.4 2 0 0 2 2 2 1 eIF-6 family Rhodanese PF00581.15 EIM90683.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Isochorismatase PF00857.15 EIM90685.1 - 5.9e-11 42.6 0.0 1.8e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Aldo_ket_red PF00248.16 EIM90686.1 - 3.9e-55 186.6 0.0 4.5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_5 PF14520.1 EIM90686.1 - 0.065 13.4 1.2 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF3129 PF11327.3 EIM90688.1 - 1.4e-55 188.0 12.0 1.4e-55 188.0 8.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) MFS_1 PF07690.11 EIM90689.1 - 1.5e-21 76.5 36.7 1.5e-21 76.5 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM90689.1 - 6.5e-05 21.5 9.9 6.5e-05 21.5 6.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIM90689.1 - 0.019 14.7 0.3 0.019 14.7 0.2 3.8 4 0 0 4 4 4 0 MFS_1 like family zf-B_box PF00643.19 EIM90693.1 - 0.0048 16.7 6.2 0.017 14.9 4.3 1.9 1 0 0 1 1 1 1 B-box zinc finger AhpC-TSA_2 PF13911.1 EIM90694.1 - 1.9e-18 66.4 0.0 3.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 EIM90694.1 - 2.2e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIM90694.1 - 4.2e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.7 EIM90694.1 - 0.16 11.3 0.4 0.94 8.8 0.0 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF899) Aa_trans PF01490.13 EIM90696.1 - 4.7e-86 288.8 31.8 5.8e-86 288.5 22.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Epimerase PF01370.16 EIM90697.1 - 9.3e-17 61.2 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM90697.1 - 1.3e-10 40.6 0.1 3.7e-09 35.8 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EIM90697.1 - 2.8e-10 39.3 0.0 7.7e-10 37.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM90697.1 - 1.5e-08 34.8 0.7 1.3e-07 31.8 0.4 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM90697.1 - 7.4e-06 25.3 0.0 6.2e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EIM90697.1 - 0.019 14.8 2.3 0.047 13.5 0.3 2.3 2 1 0 2 2 2 0 short chain dehydrogenase APH PF01636.18 EIM90698.1 - 1.1e-13 51.5 0.0 2.9e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM90698.1 - 0.0096 14.9 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EIM90698.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Rifin_STEVOR PF02009.11 EIM90699.1 - 0.043 13.4 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EIM90699.1 - 0.19 11.4 15.2 1.5 8.4 10.5 2.5 1 1 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.7 EIM90699.1 - 2 7.8 11.3 0.32 10.3 4.1 2.3 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor ECM11 PF15463.1 EIM90700.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.4 4 0 0 4 4 4 0 Extracellular mutant protein 11 Dynamin_N PF00350.18 EIM90701.1 - 5.8e-13 49.0 0.1 6.1e-12 45.6 0.0 2.7 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIM90701.1 - 2.3e-06 27.5 0.0 0.00067 19.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 EIM90701.1 - 6.8e-06 25.1 0.1 2.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain DUF258 PF03193.11 EIM90701.1 - 7e-05 22.0 0.0 0.00057 19.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIM90701.1 - 0.00014 21.8 0.0 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EIM90701.1 - 0.0015 17.5 0.0 0.0033 16.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIM90701.1 - 0.0019 18.5 0.0 0.006 16.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.1 EIM90701.1 - 0.0026 16.9 0.0 0.006 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIM90701.1 - 0.004 16.6 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FlxA PF14282.1 EIM90701.1 - 0.0049 16.8 0.2 0.045 13.7 0.2 2.6 2 0 0 2 2 2 1 FlxA-like protein AAA_22 PF13401.1 EIM90701.1 - 0.013 15.6 0.1 0.09 12.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EIM90701.1 - 0.018 15.5 0.3 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EIM90701.1 - 0.021 14.5 0.4 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EIM90701.1 - 0.26 11.5 7.2 2.2 8.5 4.9 2.6 1 1 0 1 1 1 0 AAA domain RRF PF01765.14 EIM90701.1 - 2.5 7.5 16.3 2.9 7.3 4.2 3.1 3 0 0 3 3 3 0 Ribosome recycling factor Pyr_redox_3 PF13738.1 EIM90702.1 - 2.4e-18 66.9 0.0 3.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM90702.1 - 4e-12 45.1 0.6 2e-10 39.4 0.1 2.7 1 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIM90702.1 - 4.1e-08 33.1 0.1 2.2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM90702.1 - 0.00063 19.5 0.1 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EIM90702.1 - 0.0036 16.2 0.1 0.62 8.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIM90702.1 - 0.009 14.9 0.0 0.024 13.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EIM90702.1 - 0.023 14.4 0.5 6.8 6.3 0.0 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EIM90702.1 - 0.04 12.8 0.0 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein PS_pyruv_trans PF04230.8 EIM90702.1 - 0.055 13.1 0.1 0.18 11.4 0.0 1.9 2 1 0 2 2 2 0 Polysaccharide pyruvyl transferase Pyr_redox_2 PF07992.9 EIM90702.1 - 0.059 13.2 0.0 0.34 10.7 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM90702.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Fra10Ac1 PF09725.4 EIM90703.1 - 5.4e-40 136.1 0.0 8.3e-40 135.5 0.0 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF2039 PF10217.4 EIM90703.1 - 0.027 14.4 0.4 0.054 13.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Abhydrolase_6 PF12697.2 EIM90705.1 - 3.8e-23 82.5 0.8 5.3e-23 82.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM90705.1 - 2.1e-08 34.0 0.0 7.1e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM90705.1 - 4.6e-05 23.7 0.0 0.00073 19.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 EIM90705.1 - 0.00023 20.8 0.0 0.0022 17.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EIM90705.1 - 0.044 12.6 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EIM90705.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase NAD_binding_8 PF13450.1 EIM90705.1 - 0.14 12.1 0.1 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AAA PF00004.24 EIM90706.1 - 9.1e-92 304.1 0.0 3.6e-46 156.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM90706.1 - 7.2e-15 54.6 0.0 6.7e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIM90706.1 - 2.2e-11 43.8 0.0 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM90706.1 - 4.1e-11 43.1 0.6 0.0025 17.9 0.0 4.7 4 2 0 4 4 2 2 AAA domain AAA_16 PF13191.1 EIM90706.1 - 5.6e-11 42.7 2.4 0.00088 19.3 0.1 4.3 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIM90706.1 - 9.4e-11 42.5 0.0 4.2e-05 24.3 0.0 2.7 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIM90706.1 - 3.7e-09 36.4 0.6 0.0046 16.6 0.2 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EIM90706.1 - 4.8e-09 35.4 0.0 0.00018 20.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EIM90706.1 - 6.8e-09 35.1 0.0 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 EIM90706.1 - 7.6e-09 35.7 0.0 0.0056 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIM90706.1 - 2e-08 34.1 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EIM90706.1 - 9e-08 31.5 0.3 0.0086 15.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIM90706.1 - 1.4e-07 31.0 0.0 0.0057 16.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 EIM90706.1 - 5e-07 29.5 1.7 0.033 13.8 0.1 4.0 4 0 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 EIM90706.1 - 1.2e-06 28.5 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIM90706.1 - 1.3e-06 28.0 0.3 0.063 13.0 0.1 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA_3 PF07726.6 EIM90706.1 - 1.3e-06 28.0 0.0 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIM90706.1 - 1.5e-06 27.7 4.8 0.38 10.1 0.1 4.5 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.17 EIM90706.1 - 4.2e-06 26.8 0.0 0.13 12.4 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EIM90706.1 - 3.8e-05 23.9 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EIM90706.1 - 6.6e-05 22.9 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIM90706.1 - 0.00012 21.5 0.0 0.84 9.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EIM90706.1 - 0.00014 22.2 0.0 0.51 10.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter Cytidylate_kin2 PF13189.1 EIM90706.1 - 0.00016 21.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.10 EIM90706.1 - 0.00061 18.6 0.0 0.22 10.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EIM90706.1 - 0.00061 18.9 0.0 5.4 6.0 0.0 3.2 3 0 0 3 3 3 0 KaiC SKI PF01202.17 EIM90706.1 - 0.00062 19.6 0.1 1.4 8.7 0.0 2.8 3 0 0 3 3 2 2 Shikimate kinase UPF0079 PF02367.12 EIM90706.1 - 0.00069 19.2 0.1 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EIM90706.1 - 0.00091 18.8 0.0 0.93 8.9 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EIM90706.1 - 0.0013 18.4 0.0 4.3 6.9 0.0 3.3 2 2 1 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 EIM90706.1 - 0.0019 17.0 0.0 0.76 8.5 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase PhoH PF02562.11 EIM90706.1 - 0.0025 17.0 0.3 1.2 8.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 EIM90706.1 - 0.0027 16.6 0.2 1.1 7.9 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 EIM90706.1 - 0.0075 15.2 0.0 0.38 9.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EIM90706.1 - 0.012 14.5 0.1 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EIM90706.1 - 0.014 14.9 0.0 5.6 6.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EIM90706.1 - 0.02 14.5 0.6 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIM90706.1 - 0.088 12.2 0.1 16 4.9 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 EIM90706.1 - 0.11 12.1 0.0 12 5.4 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.11 EIM90706.1 - 0.17 11.0 0.1 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF605 PF04652.11 EIM90707.1 - 0.77 9.0 11.2 1 8.6 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Serglycin PF04360.7 EIM90708.1 - 0.63 9.7 6.2 1.1 8.9 2.4 2.2 2 0 0 2 2 2 0 Serglycin DUF2668 PF10873.3 EIM90710.1 - 6.6 6.8 15.2 21 5.2 10.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) F-box-like PF12937.2 EIM90711.1 - 0.072 12.8 1.2 0.12 12.1 0.2 1.9 2 0 0 2 2 2 0 F-box-like Ribosomal_L30 PF00327.15 EIM90713.1 - 5.4e-09 35.5 0.1 8.4e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PTCB-BRCT PF12738.2 EIM90714.1 - 1.6e-32 111.1 1.0 4.1e-13 48.9 0.0 3.8 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EIM90714.1 - 7.1e-23 80.5 0.1 3.8e-09 36.5 0.0 4.3 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain F-box-like PF12937.2 EIM90715.1 - 5.7e-08 32.3 0.1 1.6e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like Tannase PF07519.6 EIM90716.1 - 0.014 14.1 0.3 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Glyco_hydro_3 PF00933.16 EIM90718.1 - 5.8e-89 298.0 0.2 1.1e-88 297.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM90718.1 - 2.5e-57 194.0 0.0 4.9e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIM90718.1 - 7.4e-22 77.0 0.4 1.5e-21 76.1 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FmdA_AmdA PF03069.10 EIM90719.1 - 2.1e-134 447.8 0.0 2.6e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.24 EIM90720.1 - 8.7e-07 28.8 0.3 4e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIM90720.1 - 0.1 12.7 0.0 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain FAD_binding_3 PF01494.14 EIM90721.1 - 1.7e-21 76.6 0.0 3e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM90721.1 - 7.3e-11 41.5 0.6 2e-06 26.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM90721.1 - 7.7e-09 34.5 0.2 5.8e-08 31.6 0.1 2.0 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EIM90721.1 - 8.7e-07 28.8 0.6 6.3e-06 26.1 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM90721.1 - 5.8e-06 25.4 0.9 1.7e-05 23.8 0.1 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIM90721.1 - 1.8e-05 25.0 0.5 0.0044 17.3 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM90721.1 - 4.7e-05 22.6 0.1 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EIM90721.1 - 7.7e-05 22.6 0.3 0.00041 20.2 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIM90721.1 - 0.0001 21.5 0.1 0.00018 20.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIM90721.1 - 0.0064 15.3 0.0 0.0091 14.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EIM90721.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIM90721.1 - 0.0067 15.3 0.4 0.056 12.3 0.2 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EIM90721.1 - 0.014 14.0 0.4 0.071 11.7 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EIM90721.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIM90722.1 - 5.1e-19 68.5 0.0 1.4e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM90722.1 - 6e-11 41.8 1.7 9.9e-07 27.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM90722.1 - 1.3e-07 31.5 0.0 6.5e-07 29.2 0.1 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM90722.1 - 2.9e-07 29.6 0.3 5.3e-07 28.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIM90722.1 - 7.7e-06 24.6 0.1 3.6e-05 22.4 0.1 2.0 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EIM90722.1 - 4.3e-05 23.8 0.9 0.0052 17.1 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM90722.1 - 0.00023 21.1 0.5 0.0022 17.9 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIM90722.1 - 0.0068 15.5 0.1 0.48 9.4 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EIM90722.1 - 0.0077 15.3 1.0 0.013 14.5 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM90722.1 - 0.011 14.7 0.1 0.045 12.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EIM90722.1 - 0.019 15.0 0.1 0.051 13.6 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIM90722.1 - 0.02 13.5 0.9 0.091 11.3 0.2 2.2 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 EIM90722.1 - 0.04 12.7 0.1 0.064 12.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EIM90722.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIM90722.1 - 0.084 11.7 0.8 0.19 10.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.17 EIM90723.1 - 5e-69 233.0 0.0 6.1e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT PF03062.14 EIM90724.1 - 1.8e-41 142.3 16.9 1.8e-41 142.3 11.7 2.4 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF973 PF06157.6 EIM90724.1 - 0.025 13.5 0.2 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) F-box-like PF12937.2 EIM90728.1 - 1.2e-09 37.7 0.6 3.7e-09 36.1 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM90728.1 - 0.00056 19.5 1.4 0.017 14.7 0.3 2.8 2 0 0 2 2 2 1 F-box domain SpoIIAA-like PF11964.3 EIM90728.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 SpoIIAA-like VirB3 PF05101.8 EIM90730.1 - 0.34 10.9 3.7 19 5.2 0.1 3.3 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein ICMT PF04140.9 EIM90731.1 - 9.7e-15 54.5 1.2 2.8e-14 53.0 0.2 2.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM90731.1 - 1.1e-12 47.9 0.8 7e-12 45.3 0.6 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIM90731.1 - 5.1e-08 31.8 0.7 6.1e-08 31.6 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIM90731.1 - 5.8e-05 22.4 0.4 0.00013 21.3 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.11 EIM90732.1 - 1.8e-23 82.8 74.6 5.2e-17 61.5 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM90732.1 - 0.0018 18.0 2.8 3.6 7.4 0.0 3.6 3 0 0 3 3 3 2 MFS_1 like family UbiA PF01040.13 EIM90733.1 - 1.8e-31 109.3 21.5 2.2e-31 109.0 14.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GMC_oxred_N PF00732.14 EIM90734.1 - 7e-57 192.8 0.0 9.6e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM90734.1 - 2.2e-36 125.3 0.0 5.4e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIM90734.1 - 0.00038 20.4 0.5 0.0023 17.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIM90734.1 - 0.0021 16.9 0.8 0.069 11.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM90734.1 - 0.0051 15.7 0.2 0.12 11.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM90734.1 - 0.012 14.5 0.2 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CK_II_beta PF01214.13 EIM90735.1 - 3.6e-70 235.2 0.0 4.3e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glutaredoxin PF00462.19 EIM90737.1 - 1.4e-18 66.6 0.0 5.3e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EIM90737.1 - 2.8e-14 52.6 0.0 5.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 EIM90737.1 - 1.2e-05 25.1 0.0 0.00026 20.8 0.0 2.3 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 EIM90737.1 - 5.1e-05 23.3 0.0 0.0035 17.4 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Phosducin PF02114.11 EIM90737.1 - 0.0034 16.1 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin SH3BGR PF04908.10 EIM90737.1 - 0.0036 17.2 0.0 0.0083 16.0 0.0 1.7 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.1 EIM90737.1 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 EIM90737.1 - 0.064 13.0 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain ArsC PF03960.10 EIM90737.1 - 0.066 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 ArsC family Thioredoxin_2 PF13098.1 EIM90737.1 - 0.083 13.0 0.0 0.78 9.9 0.0 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain Scm3 PF10384.4 EIM90738.1 - 0.12 11.8 0.7 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Centromere protein Scm3 DUF605 PF04652.11 EIM90738.1 - 0.34 10.2 10.3 0.49 9.7 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Ku PF02735.11 EIM90740.1 - 2.9e-23 82.3 0.0 7.6e-23 80.9 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EIM90740.1 - 2.1e-22 79.6 0.0 3.6e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EIM90740.1 - 5.8e-11 41.6 0.1 1.1e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EIM90740.1 - 2e-07 31.4 0.1 5.6e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm TctB PF07331.6 EIM90741.1 - 0.025 14.2 5.7 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Herpes_gE PF02480.11 EIM90741.1 - 0.1 10.8 0.5 2.3 6.4 0.0 2.5 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E DUF3154 PF11351.3 EIM90741.1 - 0.35 10.6 0.1 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF1469 PF07332.6 EIM90741.1 - 2.9 7.6 8.9 1.7 8.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) NAD_binding_4 PF07993.7 EIM90742.1 - 6.8e-35 120.1 0.0 1.2e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM90742.1 - 1.1e-24 86.6 0.0 6.5e-24 84.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM90742.1 - 9.7e-09 35.0 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM90742.1 - 1.3e-06 27.3 0.0 2.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM90742.1 - 0.00014 21.6 0.1 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM90742.1 - 0.00031 20.7 0.1 0.00079 19.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EIM90742.1 - 0.0004 20.5 0.0 0.00098 19.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Orn_Arg_deC_N PF02784.11 EIM90744.1 - 1.4e-72 243.9 0.0 1.8e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EIM90744.1 - 6.9e-30 103.1 0.0 1.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.8 EIM90745.1 - 0.0011 18.5 0.1 0.0078 15.8 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain SPX PF03105.14 EIM90746.1 - 4.7e-46 157.7 0.0 6.4e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIM90746.1 - 1.8e-26 93.0 25.2 2.6e-26 92.5 17.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIM90746.1 - 1.6e-14 53.2 24.2 9e-13 47.5 6.7 2.1 1 1 1 2 2 2 2 Citrate transporter TFIIF_alpha PF05793.7 EIM90746.1 - 0.17 10.2 5.4 0.25 9.6 3.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 EIM90746.1 - 0.47 10.7 6.2 1.9 8.8 4.3 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EIM90746.1 - 5 6.6 8.4 9.7 5.6 5.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EIM90746.1 - 7.1 4.5 9.5 11 3.9 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sdh_cyt PF01127.17 EIM90747.1 - 9e-25 86.8 0.2 1.1e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pyr_redox PF00070.22 EIM90748.1 - 2.1e-13 50.4 0.1 5.3e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM90748.1 - 1.6e-10 41.2 0.0 5.8e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM90748.1 - 0.00032 19.7 1.9 0.05 12.4 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM90748.1 - 0.0076 16.3 0.1 0.054 13.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase PCP_red PF08369.5 EIM90748.1 - 0.08 12.8 0.3 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit K_oxygenase PF13434.1 EIM90748.1 - 0.08 11.8 0.0 12 4.7 0.0 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EIM90748.1 - 0.15 12.2 0.3 5.7 7.2 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EIM90749.1 - 8.9e-16 58.0 0.1 3.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM90749.1 - 2.1e-13 50.6 0.0 7.6e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM90749.1 - 2.6e-05 24.3 0.0 0.22 11.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM90749.1 - 0.00023 20.1 0.0 0.47 9.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM90749.1 - 0.00025 20.8 0.1 2.5 7.8 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EIM90749.1 - 0.00026 20.0 0.0 0.27 10.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EIM90749.1 - 0.00029 21.0 0.2 0.61 10.3 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIM90749.1 - 0.00048 19.1 0.8 1.6 7.5 0.0 2.8 2 1 1 3 3 3 3 Lycopene cyclase protein TrkA_N PF02254.13 EIM90749.1 - 0.05 13.6 0.1 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 EIM90749.1 - 0.054 12.3 0.3 3.9 6.2 0.0 2.3 2 1 0 2 2 2 0 FAD binding domain DUF2945 PF11160.3 EIM90750.1 - 0.041 13.6 1.8 0.093 12.5 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) F-box PF00646.28 EIM90751.1 - 0.00036 20.1 0.7 0.00036 20.1 0.5 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM90751.1 - 0.00074 19.1 0.4 0.0034 17.0 0.3 2.3 1 0 0 1 1 1 1 F-box-like PTPA PF03095.10 EIM90753.1 - 2e-95 319.4 0.0 2.5e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Peptidase_M1 PF01433.15 EIM90754.1 - 5.9e-110 368.0 0.1 2.1e-109 366.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EIM90754.1 - 7.1e-59 199.6 1.4 1.4e-58 198.7 1.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIM90754.1 - 1.3e-15 57.5 0.0 3.8e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily CBM_5_12 PF02839.9 EIM90755.1 - 1.3e-11 43.8 3.3 1.3e-11 43.8 2.3 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_18 PF00704.23 EIM90755.1 - 4.5e-07 29.6 7.2 5.8e-06 25.9 5.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.13 EIM90756.1 - 6.5e-08 32.3 15.3 1.5e-07 31.1 10.6 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM90756.1 - 0.16 11.8 6.7 2.8 7.8 5.2 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_M1 PF01433.15 EIM90757.1 - 1.1e-108 363.7 0.0 5.7e-107 358.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EIM90757.1 - 4.7e-58 196.9 2.8 6.5e-58 196.4 1.9 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIM90757.1 - 9.3e-16 58.0 0.1 4.7e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase MA superfamily HEAT_2 PF13646.1 EIM90757.1 - 0.0089 16.2 1.7 0.36 11.1 0.8 3.0 2 1 0 2 2 2 1 HEAT repeats MazG-like PF12643.2 EIM90757.1 - 0.084 12.8 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 MazG-like family Acyltransferase PF01553.16 EIM90759.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase DUF2573 PF10835.3 EIM90760.1 - 0.032 14.2 0.4 0.87 9.6 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2573) Ecm29 PF13001.2 EIM90762.1 - 0.068 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Proteasome stabiliser Maf PF02545.9 EIM90763.1 - 3.3e-40 137.3 0.0 4.4e-38 130.3 0.0 2.0 1 1 0 1 1 1 1 Maf-like protein ADH_zinc_N PF00107.21 EIM90763.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DSBA PF01323.15 EIM90765.1 - 7.4e-21 74.5 0.0 9.1e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 EIM90766.1 - 1.2e-18 67.6 0.0 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM90766.1 - 2.8e-06 27.1 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM90766.1 - 3.7e-06 26.8 0.1 4.5e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIM90766.1 - 0.11 12.2 0.4 0.25 11.1 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AceK PF06315.6 EIM90766.1 - 0.14 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) FHA PF00498.21 EIM90767.1 - 3.6e-08 33.3 0.0 7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Antimicrobial14 PF08109.6 EIM90770.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Lactocin 705 family Cyclin_N PF00134.18 EIM90772.1 - 4e-43 146.0 0.1 9.4e-43 144.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIM90772.1 - 1.9e-24 85.8 0.1 5.9e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Tup_N PF08581.5 EIM90772.1 - 0.55 10.4 5.7 0.35 11.0 1.4 2.3 2 0 0 2 2 2 0 Tup N-terminal ADH_zinc_N PF00107.21 EIM90773.1 - 3e-18 65.6 0.0 5.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM90773.1 - 1.1e-09 39.2 0.0 2.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyoxal_oxid_N PF07250.6 EIM90773.1 - 0.048 12.7 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus ADH_zinc_N PF00107.21 EIM90774.1 - 9.8e-19 67.1 0.2 2.5e-18 65.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM90774.1 - 1.7e-10 40.6 0.0 5e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM90774.1 - 0.0022 18.8 0.0 0.0039 18.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TFIIA_gamma_N PF02268.11 EIM90774.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain RhoGEF PF00621.15 EIM90775.1 - 2.1e-33 115.7 0.0 2.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EIM90775.1 - 4.6e-29 101.7 0.0 6.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIM90775.1 - 4e-08 33.2 0.0 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIM90775.1 - 0.0014 18.8 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3292 PF11696.3 EIM90776.1 - 0.21 9.4 0.0 0.21 9.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) Peptidase_C14 PF00656.17 EIM90777.1 - 1.1e-19 71.1 0.0 2.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DUF218 PF02698.12 EIM90777.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain Peptidase_C14 PF00656.17 EIM90778.1 - 9.9e-17 61.4 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 EIM90779.1 - 2.6e-34 118.6 0.0 4.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM90779.1 - 1.6e-30 104.8 16.9 0.014 15.3 0.0 13.8 7 3 8 16 16 15 10 Tetratricopeptide repeat TPR_11 PF13414.1 EIM90779.1 - 3.1e-25 87.5 9.9 0.00022 20.7 0.0 11.5 3 2 9 13 13 13 8 TPR repeat TPR_2 PF07719.12 EIM90779.1 - 1.8e-15 55.5 6.1 0.14 12.1 0.0 12.2 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM90779.1 - 3e-10 39.0 5.1 0.82 9.6 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM90779.1 - 1.9e-09 37.9 19.4 0.035 14.7 0.6 9.0 4 2 5 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM90779.1 - 2e-09 36.6 4.5 0.14 11.7 0.0 9.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM90779.1 - 3.9e-08 32.5 0.0 0.26 11.1 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIM90779.1 - 7.8e-06 26.0 15.8 3.8 8.3 0.1 10.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIM90779.1 - 0.00014 21.7 26.7 1.5 8.8 0.0 10.5 11 0 0 11 11 11 2 Tetratricopeptide repeat Rapamycin_bind PF08771.6 EIM90779.1 - 0.14 12.2 0.2 2.1e+02 2.0 0.0 5.1 6 0 0 6 6 4 0 Rapamycin binding domain CRISPR_Cse2 PF09485.5 EIM90779.1 - 0.15 12.1 2.8 27 4.8 0.0 5.3 4 2 0 6 6 6 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_17 PF13431.1 EIM90779.1 - 0.18 12.0 2.2 4.8 7.6 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat BMC PF00936.14 EIM90779.1 - 2.4 7.9 10.6 1.2e+02 2.4 0.1 6.8 9 0 0 9 9 8 0 BMC domain Mannitol_dh_C PF08125.8 EIM90780.1 - 1e-07 31.4 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Peptidase_C14 PF00656.17 EIM90781.1 - 2.7e-13 50.2 0.0 4.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DIM1 PF02966.11 EIM90781.1 - 0.079 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 CHAT PF12770.2 EIM90781.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 CHAT domain DUF3337 PF11816.3 EIM90782.1 - 0.21 10.9 5.2 0.15 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Dicty_REP PF05086.7 EIM90782.1 - 1.7 6.2 3.2 2.6 5.6 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acetyltransf_3 PF13302.1 EIM90783.1 - 8.4e-14 51.9 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM90783.1 - 0.0015 18.4 0.0 0.0068 16.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Transpep_BrtH PF14399.1 EIM90783.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Asp PF00026.18 EIM90784.1 - 5.9e-43 147.3 0.3 1e-42 146.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM90784.1 - 1e-06 28.8 1.4 3.2e-06 27.2 0.3 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cullin PF00888.17 EIM90785.1 - 1.1e-145 486.5 0.0 1.3e-145 486.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIM90785.1 - 2.2e-28 97.8 1.9 4.5e-28 96.8 1.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Xpo1 PF08389.7 EIM90786.1 - 8.7e-20 71.1 0.2 2e-18 66.7 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EIM90786.1 - 0.012 15.6 0.1 0.22 11.7 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 EIM90786.1 - 0.015 15.5 0.1 1.3 9.3 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats DnaJ PF00226.26 EIM90788.1 - 2e-23 81.8 3.3 3.2e-23 81.2 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIM90788.1 - 2e-20 72.4 0.0 2.4e-18 65.8 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIM90788.1 - 2.2e-16 59.6 14.9 4e-16 58.8 10.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIM90788.1 - 3.7e-06 26.5 1.1 0.02 14.5 0.0 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EIM90788.1 - 0.0085 16.3 9.1 0.091 13.0 0.3 3.2 1 1 1 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 EIM90788.1 - 0.75 9.6 12.0 5.4 6.9 8.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EIM90788.1 - 8.9 5.6 8.1 6.2 6.1 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIM90788.1 - 9.5 6.2 14.3 35 4.4 1.0 3.9 2 2 2 4 4 4 0 Zinc ribbon domain YL1_C PF08265.6 EIM90789.1 - 1.4e-15 56.5 0.2 1.9e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Acetyltransf_2 PF00797.12 EIM90792.1 - 8.7e-21 74.5 0.1 1.4e-17 64.0 0.0 3.2 2 1 0 2 2 2 1 N-acetyltransferase Ribosomal_L10 PF00466.15 EIM90793.1 - 3e-25 88.0 0.1 6.7e-25 86.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EIM90793.1 - 1.7e-19 69.9 12.2 2.2e-19 69.6 6.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein PPR_2 PF13041.1 EIM90794.1 - 0.021 14.7 0.2 9.4 6.2 0.0 2.7 2 0 0 2 2 2 0 PPR repeat family DAGK_prokar PF01219.14 EIM90795.1 - 0.074 12.6 0.9 0.14 11.7 0.6 1.5 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase Glyco_hydro_3 PF00933.16 EIM90800.1 - 9.4e-21 74.0 0.2 7.9e-13 48.0 0.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIM90800.1 - 0.051 13.0 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain STE3 PF02076.10 EIM90801.1 - 0.13 11.3 0.2 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Pheromone A receptor DoxX_3 PF13781.1 EIM90801.1 - 0.19 12.0 0.2 0.19 12.0 0.1 1.5 2 0 0 2 2 2 0 DoxX-like family HLH PF00010.21 EIM90802.1 - 1.5e-06 27.7 0.0 1.5e-05 24.5 0.0 2.6 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF2413 PF10310.4 EIM90802.1 - 0.091 11.5 0.7 0.13 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 EIM90802.1 - 1.2 8.9 4.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.11 EIM90804.1 - 4.4e-33 114.4 31.6 4.4e-33 114.4 21.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 EIM90805.1 - 6.5e-51 172.2 0.1 2.3e-27 95.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIM90805.1 - 1.1e-44 152.9 28.7 1.9e-22 79.9 9.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EIM90805.1 - 9.2e-08 32.3 0.7 0.041 13.8 0.6 4.4 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 EIM90805.1 - 1.7e-07 30.7 3.5 0.00051 19.3 0.8 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EIM90805.1 - 0.00015 21.6 2.6 0.11 12.4 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIM90805.1 - 0.00016 21.1 0.6 0.53 9.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIM90805.1 - 0.00018 22.0 1.5 0.47 10.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EIM90805.1 - 0.00025 20.2 1.5 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIM90805.1 - 0.00027 20.4 0.0 0.52 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EIM90805.1 - 0.00064 19.4 0.1 0.036 13.7 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EIM90805.1 - 0.0021 18.0 4.1 0.25 11.3 0.3 2.8 2 2 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EIM90805.1 - 0.0034 16.4 0.3 0.75 8.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EIM90805.1 - 0.0064 16.1 1.0 0.31 10.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EIM90805.1 - 0.012 15.7 2.6 2.6 8.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EIM90805.1 - 0.017 14.5 1.6 4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EIM90805.1 - 0.017 15.4 0.0 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIM90805.1 - 0.018 14.7 1.3 3.3 7.4 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EIM90805.1 - 0.035 13.7 0.9 11 5.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIM90805.1 - 0.055 14.2 1.3 19 6.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIM90805.1 - 0.09 12.6 1.7 5.6 6.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EIM90805.1 - 0.11 12.7 0.4 9.1 6.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EIM90805.1 - 0.11 11.9 0.6 13 5.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EIM90805.1 - 0.12 12.1 6.0 1.4 8.7 0.4 2.6 2 0 0 2 2 2 0 Dynamin family AAA PF00004.24 EIM90805.1 - 0.2 11.8 1.1 8.4 6.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EIM90805.1 - 0.24 11.0 3.0 0.35 10.5 0.1 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EIM90805.1 - 0.73 9.2 2.7 4.6 6.6 0.4 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EIM90805.1 - 2.4 7.9 5.2 0.6 9.8 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Exo_endo_phos PF03372.18 EIM90806.1 - 8.1e-12 45.5 0.5 3.1e-07 30.6 0.0 3.2 3 0 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family SH3_9 PF14604.1 EIM90807.1 - 2.8e-14 52.4 0.1 4.1e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM90807.1 - 2.6e-13 49.2 0.0 4.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM90807.1 - 2.5e-12 45.9 0.2 3.6e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 SH3 domain DUF4279 PF14106.1 EIM90807.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DSBA PF01323.15 EIM90808.1 - 1.6e-29 102.8 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EIM90808.1 - 1e-05 25.6 0.6 4.1e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 EIM90808.1 - 0.024 14.1 0.1 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin WD40 PF00400.27 EIM90809.1 - 3e-19 68.1 7.5 6.7e-10 38.4 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 EIM90809.1 - 3e-06 27.0 0.3 6.7e-06 25.9 0.2 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EIM90809.1 - 0.00023 20.4 0.5 0.15 11.4 0.0 3.0 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature PD40 PF07676.7 EIM90809.1 - 0.0007 19.1 2.3 0.2 11.3 0.0 3.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIM90809.1 - 0.0061 14.9 0.0 0.0097 14.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome D1 heme domain Lactonase PF10282.4 EIM90809.1 - 0.016 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Coatomer_WDAD PF04053.9 EIM90809.1 - 0.027 13.2 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region PAP2_C PF14360.1 EIM90809.1 - 0.054 13.7 0.1 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CPSF_A PF03178.10 EIM90809.1 - 0.11 11.5 0.0 0.78 8.7 0.0 2.0 1 1 0 1 1 1 0 CPSF A subunit region FDX-ACB PF03147.9 EIM90810.1 - 0.11 12.6 0.3 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Pkinase PF00069.20 EIM90811.1 - 1.5e-32 112.7 0.0 2e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90811.1 - 8e-10 38.2 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90811.1 - 0.00014 21.7 0.2 0.64 9.7 0.0 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family SET PF00856.23 EIM90812.1 - 4e-11 43.4 0.1 8.9e-10 39.1 0.1 2.4 1 1 0 1 1 1 1 SET domain F-box-like PF12937.2 EIM90814.1 - 7.2e-08 32.0 0.0 2.7e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM90814.1 - 1.2 8.8 5.9 35 4.1 0.0 4.5 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_S10 PF00338.17 EIM90815.1 - 5.1e-31 106.3 0.5 5.9e-31 106.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.8 EIM90816.1 - 6.3e-59 199.8 0.1 7.7e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Med15_fungi PF05397.7 EIM90817.1 - 0.0013 18.6 1.7 0.0013 18.6 1.2 1.6 2 0 0 2 2 2 1 Mediator complex subunit 15 Meth_synt_2 PF01717.13 EIM90817.1 - 0.014 14.3 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain CDC27 PF09507.5 EIM90817.1 - 1.6 7.8 20.6 3.2 6.8 14.2 1.6 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF572 PF04502.8 EIM90819.1 - 2.9e-53 181.2 0.5 3.3e-53 181.0 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ARID PF01388.16 EIM90820.1 - 3.9e-10 39.4 0.0 3.3e-09 36.4 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain 5_3_exonuc PF01367.15 EIM90820.1 - 0.0022 18.1 1.5 0.0046 17.1 0.3 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Med15_fungi PF05397.7 EIM90820.1 - 0.0031 17.4 1.3 0.0031 17.4 0.9 3.6 4 0 0 4 4 4 1 Mediator complex subunit 15 Meth_synt_2 PF01717.13 EIM90820.1 - 0.037 13.0 0.1 0.065 12.1 0.1 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Fungal_trans PF04082.13 EIM90825.1 - 1.1e-16 60.5 0.0 1.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM90825.1 - 2.3e-07 30.6 14.0 4.2e-07 29.7 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 EIM90826.1 - 4.5e-24 84.9 0.1 5.2e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM90826.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M20 PF01546.23 EIM90827.1 - 5.2e-16 58.7 0.0 7.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ PF00226.26 EIM90828.1 - 2.9e-18 65.3 0.2 5.2e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Nucleo_P87 PF07267.6 EIM90828.1 - 0.0086 14.8 0.5 0.012 14.3 0.3 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EIM90828.1 - 0.013 15.8 3.6 0.025 14.8 2.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.7 EIM90828.1 - 0.73 9.0 6.1 0.2 10.8 0.1 2.0 2 0 0 2 2 2 0 SDA1 cobW PF02492.14 EIM90829.1 - 2.1e-38 131.5 0.1 2.8e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EIM90829.1 - 0.00027 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EIM90829.1 - 0.0026 17.4 0.0 0.0078 15.9 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EIM90829.1 - 0.0028 17.0 0.1 0.018 14.4 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Alg14 PF08660.6 EIM90829.1 - 0.058 13.3 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like AAA_22 PF13401.1 EIM90829.1 - 0.077 13.1 0.6 1.9 8.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain Frag1 PF10277.4 EIM90830.1 - 1.1e-36 126.3 6.2 2.8e-36 125.0 4.3 1.7 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EIM90830.1 - 7.5e-05 22.7 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.15 EIM90831.1 - 2.1e-118 395.9 0.5 2.9e-118 395.4 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIM90831.1 - 7.4e-08 32.5 5.1 0.0088 16.3 0.1 5.0 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EIM90831.1 - 0.0005 20.4 7.4 0.47 11.0 0.0 4.5 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EIM90831.1 - 0.00094 19.0 9.6 1.5 9.1 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.2 EIM90831.1 - 0.054 13.4 3.6 1.8 8.5 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EIM90831.1 - 0.44 10.3 5.7 2.7 7.8 0.0 3.9 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Gti1_Pac2 PF09729.4 EIM90832.1 - 1.6e-29 102.9 3.4 2.7e-25 89.1 0.2 2.1 1 1 0 2 2 2 2 Gti1/Pac2 family ESCRT-II PF05871.7 EIM90833.1 - 1.1e-32 112.8 0.1 1.5e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sugar_tr PF00083.19 EIM90835.1 - 2.5e-98 329.5 19.3 3.2e-98 329.2 13.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM90835.1 - 2.6e-22 79.0 58.7 6.3e-21 74.4 22.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM90835.1 - 5.6e-05 21.5 1.2 8.9e-05 20.8 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EIM90835.1 - 0.0076 14.9 0.6 0.0076 14.9 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) SH3_9 PF14604.1 EIM90836.1 - 0.00079 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM90836.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain TMEMspv1-c74-12 PF11044.3 EIM90836.1 - 0.041 13.4 0.1 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein WD40 PF00400.27 EIM90838.1 - 3.4e-19 67.9 8.7 1.1e-05 25.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Rpn3_C PF08375.6 EIM90838.1 - 0.071 13.5 3.2 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal G-alpha PF00503.15 EIM90839.1 - 2.7e-131 437.8 0.0 3.4e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM90839.1 - 7.6e-12 44.8 0.0 1.2e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EIM90839.1 - 0.001 18.4 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.1 EIM90839.1 - 0.005 16.3 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EIM90839.1 - 0.0061 15.7 0.4 1.3 8.1 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF2423 PF10338.4 EIM90839.1 - 0.04 13.8 9.0 3.5 7.6 0.2 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2423) DUF3567 PF12091.3 EIM90839.1 - 0.04 13.8 0.0 1.4 8.9 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3567) Pro_isomerase PF00160.16 EIM90840.1 - 1.6e-48 164.8 0.0 1.9e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.12 EIM90841.1 - 3.1e-103 344.1 0.0 3.7e-103 343.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit THUMP PF02926.12 EIM90842.1 - 4.5e-12 46.0 0.8 1.1e-11 44.8 0.6 1.6 1 0 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.6 EIM90842.1 - 0.0012 18.8 0.2 0.74 10.0 0.0 2.8 3 0 0 3 3 3 2 Adipokinetic hormone Cwf_Cwc_15 PF04889.7 EIM90842.1 - 0.025 14.3 0.8 0.044 13.4 0.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_trans_4_3 PF12000.3 EIM90843.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group Acetate_kinase PF00871.12 EIM90844.1 - 3.2e-87 292.5 0.0 7.2e-87 291.4 0.0 1.5 1 1 0 1 1 1 1 Acetokinase family XFP_N PF09364.5 EIM90845.1 - 4.5e-153 509.3 0.0 5.7e-153 508.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EIM90845.1 - 2.9e-69 232.2 0.0 4.6e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EIM90845.1 - 1.5e-64 217.1 0.0 2.8e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EIM90845.1 - 0.0064 16.0 0.3 0.018 14.5 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p450 PF00067.17 EIM90846.1 - 5.4e-56 190.0 0.0 1.4e-55 188.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 EIM90848.1 - 2.2e-24 84.9 2.1 2.2e-24 84.9 1.5 2.1 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.3 EIM90848.1 - 5.4e-10 39.1 0.2 1.5e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM90848.1 - 5.6e-08 32.7 0.5 5.6e-08 32.7 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIM90848.1 - 0.0022 18.0 0.4 0.006 16.6 0.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIM90848.1 - 0.075 13.3 0.2 0.29 11.5 0.2 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM90848.1 - 0.38 11.1 2.0 0.79 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Tim10_DDP PF02953.10 EIM90849.1 - 3.3e-21 74.3 1.7 4.4e-21 73.9 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 EIM90849.1 - 0.005 16.6 1.1 0.006 16.3 0.8 1.1 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein Homeobox PF00046.24 EIM90850.1 - 1.3e-17 63.1 4.5 2.9e-17 61.9 3.1 1.7 1 0 0 1 1 1 1 Homeobox domain U1snRNP70_N PF12220.3 EIM90851.1 - 7.7e-17 61.3 1.5 1.7e-16 60.3 1.0 1.6 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EIM90851.1 - 5.2e-15 54.8 0.0 1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM90851.1 - 2.3e-12 46.6 0.0 3.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90851.1 - 2e-06 27.5 0.2 6.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3383 PF11863.3 EIM90851.1 - 0.062 11.9 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) UbiA PF01040.13 EIM90852.1 - 1.6e-29 102.9 20.6 2.3e-29 102.4 14.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3505 PF12013.3 EIM90853.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EIM90853.1 - 0.05 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIM90853.1 - 0.058 13.5 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIM90853.1 - 0.12 12.5 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Prp18 PF02840.10 EIM90854.1 - 5.1e-58 195.0 0.1 5.1e-58 195.0 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EIM90854.1 - 3e-11 42.3 3.9 8e-11 41.0 2.7 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like MACPF PF01823.14 EIM90854.1 - 0.044 13.4 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 MAC/Perforin domain PV-1 PF06637.6 EIM90854.1 - 0.57 8.6 6.5 0.83 8.1 4.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) U79_P34 PF03064.11 EIM90854.1 - 8.9 5.7 13.4 1.4 8.3 1.1 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 COX6B PF02297.12 EIM90855.1 - 1.3e-19 69.9 6.1 1.5e-19 69.7 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EIM90855.1 - 0.013 15.4 1.4 0.035 14.0 0.9 1.8 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 EIM90855.1 - 1.2 9.0 7.1 4.9 7.0 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Abhydrolase_6 PF12697.2 EIM90856.1 - 1.5e-19 70.7 0.0 1.9e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM90856.1 - 5.1e-07 29.4 0.0 4.9e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM90856.1 - 7.1e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIM90856.1 - 1.9e-05 24.2 0.0 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIM90856.1 - 0.00073 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 EIM90856.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 1 0 1 1 1 0 Secretory lipase Abhydrolase_4 PF08386.5 EIM90856.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Citrate_synt PF00285.16 EIM90857.1 - 9.6e-98 327.1 0.0 1.3e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Transglut_core PF01841.14 EIM90858.1 - 9.7e-11 41.8 0.1 2.5e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.7 EIM90858.1 - 0.0051 16.0 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 Transglutaminase-like domain Peptidase_C2 PF00648.16 EIM90859.1 - 7.1e-63 212.3 4.7 3.1e-42 144.6 0.6 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Methyltransf_31 PF13847.1 EIM90860.1 - 2.2e-14 53.2 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM90860.1 - 4.4e-13 49.8 0.0 5.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM90860.1 - 6.5e-07 29.2 0.0 8.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM90860.1 - 3.2e-06 27.1 0.0 1.4e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM90860.1 - 1e-05 24.9 0.0 3.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIM90860.1 - 0.00031 21.1 0.0 0.00053 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM90860.1 - 0.0049 17.3 0.0 0.018 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM90860.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3421 PF11901.3 EIM90861.1 - 9e-17 60.9 0.1 1.5e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) MIF4G PF02854.14 EIM90862.1 - 2.5e-31 108.7 4.5 3.8e-31 108.1 3.1 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EIM90862.1 - 1.9e-19 69.4 0.3 9.5e-19 67.1 0.0 2.4 3 0 0 3 3 3 1 MA3 domain EBV-NA3 PF05009.7 EIM90862.1 - 1.9 7.6 5.1 12 5.0 0.0 2.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Pyr_redox_3 PF13738.1 EIM90863.1 - 8.6e-24 84.7 0.1 2.5e-22 79.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM90863.1 - 1.2e-19 69.8 0.0 9.6e-13 47.1 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM90863.1 - 3.2e-12 46.0 0.0 5.5e-07 28.8 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM90863.1 - 3.8e-07 30.1 0.0 7e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIM90863.1 - 4.1e-07 30.1 0.3 0.00026 21.1 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EIM90863.1 - 4.7e-05 22.6 0.2 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIM90863.1 - 8.5e-05 22.5 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EIM90863.1 - 0.00023 21.1 0.4 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 EIM90863.1 - 0.00057 20.2 0.7 0.62 10.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM90863.1 - 0.00074 18.5 0.0 0.028 13.3 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.11 EIM90863.1 - 0.00079 18.8 0.0 0.022 14.2 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EIM90863.1 - 0.0016 17.5 0.1 0.025 13.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EIM90863.1 - 0.01 15.5 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIM90863.1 - 0.019 13.4 0.1 0.077 11.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EIM90863.1 - 0.022 14.5 0.1 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIM90863.1 - 0.026 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 EIM90863.1 - 0.028 14.2 1.2 6.8 6.5 0.1 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EIM90863.1 - 0.034 14.4 0.0 4.8 7.4 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EIM90863.1 - 0.052 12.4 0.1 0.56 9.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EIM90863.1 - 0.057 12.5 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 EIM90864.1 - 6.4e-33 113.9 25.5 6.4e-33 113.9 17.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM90864.1 - 5.2e-11 41.7 11.2 5.2e-11 41.7 7.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIM90864.1 - 3.5 5.6 13.1 0.028 12.6 2.5 2.2 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Metallophos PF00149.23 EIM90865.1 - 8.1e-42 142.8 0.7 1e-41 142.5 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 EIM90865.1 - 0.089 11.8 0.4 0.18 10.8 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez cwf21 PF08312.7 EIM90865.1 - 0.15 11.9 0.3 0.35 10.7 0.2 1.6 1 0 0 1 1 1 0 cwf21 domain Cpn60_TCP1 PF00118.19 EIM90866.1 - 3.5e-143 477.7 0.6 4e-143 477.5 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_1 PF00561.15 EIM90867.1 - 4.2e-29 101.7 0.0 1.4e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM90867.1 - 2.4e-25 89.7 0.0 3.3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM90867.1 - 6.1e-11 42.2 0.0 6e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM90867.1 - 0.0058 15.8 0.0 0.8 8.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EIM90867.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 EIM90867.1 - 0.028 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 EIM90867.1 - 0.059 11.8 0.0 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.7 EIM90867.1 - 0.079 11.5 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ser_hydrolase PF06821.8 EIM90867.1 - 0.083 12.4 0.2 1.8 8.1 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase EHN PF06441.7 EIM90867.1 - 0.12 12.3 0.5 0.48 10.3 0.0 2.2 3 0 0 3 3 3 0 Epoxide hydrolase N terminus CRAL_TRIO PF00650.15 EIM90868.1 - 2.8e-28 98.4 0.0 4e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIM90868.1 - 3.1e-07 30.3 0.1 7.6e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FAD_binding_3 PF01494.14 EIM90869.1 - 4.9e-19 68.5 0.0 7.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM90869.1 - 0.01 15.8 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sad1_UNC PF07738.8 EIM90870.1 - 2.6e-25 88.7 0.0 1.1e-12 47.9 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal APG6 PF04111.7 EIM90872.1 - 0.11 11.4 1.3 0.18 10.7 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EIM90872.1 - 2.2 7.8 5.6 48 3.5 0.0 2.8 2 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EIM90872.1 - 4.3 6.9 8.0 1.7 8.2 3.5 1.7 2 0 0 2 2 2 0 IncA protein F-box-like PF12937.2 EIM90873.1 - 0.0065 16.1 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Exo_endo_phos PF03372.18 EIM90874.1 - 1.6e-07 31.5 3.0 2.4e-07 30.9 2.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EIM90874.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Aldo_ket_red PF00248.16 EIM90875.1 - 3.4e-51 173.7 0.0 4.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Yip1 PF04893.12 EIM90877.1 - 3.7e-14 52.6 17.0 5.6e-14 52.0 11.8 1.3 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 EIM90877.1 - 0.0017 18.2 2.0 0.0017 18.2 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) AAA PF00004.24 EIM90878.1 - 2.2e-41 141.1 0.0 3.8e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM90878.1 - 1.9e-06 28.0 0.1 0.00035 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIM90878.1 - 4.8e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIM90878.1 - 5.3e-05 22.2 0.0 9.2e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIM90878.1 - 0.00012 21.8 0.2 0.00074 19.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIM90878.1 - 0.00022 21.2 0.1 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIM90878.1 - 0.00062 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIM90878.1 - 0.0041 17.0 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIM90878.1 - 0.0045 16.5 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIM90878.1 - 0.0061 17.3 0.7 0.017 15.9 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EIM90878.1 - 0.0064 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM90878.1 - 0.0066 16.1 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EIM90878.1 - 0.0067 16.4 0.2 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EIM90878.1 - 0.0071 15.4 0.1 0.2 10.7 0.0 2.2 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.12 EIM90878.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIM90878.1 - 0.012 14.9 0.4 0.74 9.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EIM90878.1 - 0.013 15.7 0.5 0.035 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIM90878.1 - 0.017 14.7 0.1 0.42 10.2 0.1 2.7 2 1 1 3 3 3 0 NACHT domain NB-ARC PF00931.17 EIM90878.1 - 0.038 12.8 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EIM90878.1 - 0.052 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 EIM90878.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 EIM90878.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EIM90878.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EIM90878.1 - 0.096 12.5 0.0 4 7.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase RNA_helicase PF00910.17 EIM90878.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EIM90878.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIM90878.1 - 0.16 11.5 0.2 0.39 10.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain Citrate_synt PF00285.16 EIM90879.1 - 1.3e-116 389.1 0.0 1.6e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Brix PF04427.13 EIM90880.1 - 5.4e-30 104.4 0.3 7e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Brix domain Gon7 PF08738.5 EIM90880.1 - 2.4 8.1 5.9 0.93 9.5 0.8 2.4 2 0 0 2 2 2 0 Gon7 family F-box-like PF12937.2 EIM90881.1 - 5.5e-09 35.6 1.2 1.4e-08 34.2 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM90881.1 - 1.2e-06 28.0 2.4 2.4e-06 27.0 0.7 2.3 3 0 0 3 3 3 1 F-box domain DUF883 PF05957.8 EIM90882.1 - 1.9 8.9 9.5 2.5 8.5 2.4 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Epimerase PF01370.16 EIM90883.1 - 5.7e-05 22.6 0.1 0.00041 19.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Dioxygenase_C PF00775.16 EIM90885.1 - 5.7e-08 32.2 0.1 1e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Abhydrolase_6 PF12697.2 EIM90889.1 - 1.5e-26 93.7 0.0 1.9e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM90889.1 - 1.2e-14 54.3 0.0 1.7e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIM90889.1 - 1.6e-10 40.9 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EIM90889.1 - 6.3e-10 38.9 0.9 1.4e-09 37.8 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIM90889.1 - 4.9e-07 30.2 0.0 5.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EIM90889.1 - 4.4e-05 22.8 0.0 6.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2048 PF09752.4 EIM90889.1 - 0.0002 20.3 0.6 0.0031 16.4 0.4 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 EIM90889.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EIM90889.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EIM90889.1 - 0.0058 15.4 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EIM90889.1 - 0.0069 15.3 0.2 0.015 14.1 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme DUF900 PF05990.7 EIM90889.1 - 0.069 12.4 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.15 EIM90889.1 - 0.15 11.4 0.3 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Putative esterase RF-1 PF00472.15 EIM90891.1 - 2.2e-16 59.6 0.1 3.3e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 RF-1 domain Herpes_IE2_3 PF03361.9 EIM90891.1 - 0.14 11.4 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 FlaF PF07309.6 EIM90892.1 - 0.04 13.7 0.8 0.098 12.5 0.6 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Tropomyosin_1 PF12718.2 EIM90892.1 - 0.099 12.4 0.2 0.099 12.4 0.1 1.8 2 0 0 2 2 2 0 Tropomyosin like DUF2450 PF10475.4 EIM90892.1 - 0.18 10.6 0.6 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DcpS_C PF11969.3 EIM90893.1 - 2.6e-25 88.8 0.7 3.2e-25 88.6 0.5 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIM90893.1 - 2.2e-13 50.5 0.8 3e-13 50.1 0.5 1.2 1 0 0 1 1 1 1 HIT domain DGF-1_4 PF11024.3 EIM90894.1 - 1.9 8.9 7.3 12 6.3 5.1 2.4 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 BUD22 PF09073.5 EIM90896.1 - 3.7 6.5 12.1 5.4 5.9 8.4 1.3 1 0 0 1 1 1 0 BUD22 BTB PF00651.26 EIM90897.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Dysbindin PF04440.11 EIM90898.1 - 0.096 12.4 2.1 0.11 12.3 1.5 1.2 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DnaJ-X PF14308.1 EIM90898.1 - 0.097 11.9 7.6 0.11 11.8 5.3 1.0 1 0 0 1 1 1 0 X-domain of DnaJ-containing Spore_coat_CotO PF14153.1 EIM90898.1 - 0.19 11.1 10.4 0.21 11.0 7.2 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Wound_ind PF08186.6 EIM90898.1 - 1.5 8.7 5.1 0.4 10.6 1.2 1.8 2 0 0 2 2 2 0 Wound-inducible basic protein family Fork_head PF00250.13 EIM90899.1 - 7.1e-26 90.0 0.0 8.6e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Fork head domain RNase_HII PF01351.13 EIM90900.1 - 8.3e-44 149.6 0.0 1.9e-41 141.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII T2SG PF08334.6 EIM90900.1 - 0.14 11.9 1.7 1.8 8.3 0.2 2.8 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein G Aldo_ket_red PF00248.16 EIM90901.1 - 1.4e-43 148.7 0.0 1.8e-21 76.1 0.0 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family Clathrin_lg_ch PF01086.12 EIM90902.1 - 0.033 14.1 0.2 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 Clathrin light chain DUF3613 PF12266.3 EIM90902.1 - 0.037 13.5 0.8 0.069 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) PLRV_ORF5 PF01690.12 EIM90903.1 - 0.0087 15.2 3.6 0.013 14.6 2.5 1.2 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein Trypan_PARP PF05887.6 EIM90903.1 - 0.011 15.5 0.3 0.019 14.7 0.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Beta-lactamase PF00144.19 EIM90904.1 - 8.5e-33 113.7 0.4 1.2e-32 113.3 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 EIM90905.1 - 1.6e-15 56.7 32.6 2.9e-15 55.8 22.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM90905.1 - 5.9e-07 28.4 22.5 2.9e-06 26.1 6.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter UNC-93 PF05978.11 EIM90905.1 - 1.9e-06 27.4 1.9 1.9e-06 27.4 1.3 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 OAD_gamma PF04277.8 EIM90905.1 - 0.057 13.7 0.1 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_43 PF04616.9 EIM90906.1 - 1.2e-21 77.0 22.0 6.9e-10 38.4 1.1 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 Peptidase_M48 PF01435.13 EIM90907.1 - 1.5e-13 50.8 0.0 2.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 EIM90907.1 - 0.0085 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 EIM90907.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Dioxygenase_C PF00775.16 EIM90908.1 - 8.3e-09 34.9 1.1 2.4e-08 33.4 0.7 1.8 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.16 EIM90909.1 - 1.9e-08 33.7 0.1 3.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase Na_Ca_ex PF01699.19 EIM90911.1 - 1.7e-24 86.0 25.0 8.3e-14 51.3 7.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COX5B PF01215.14 EIM90912.1 - 2.7e-34 117.7 0.0 3.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Beta-lactamase PF00144.19 EIM90913.1 - 5.1e-32 111.1 0.4 7.4e-32 110.6 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase DPBB_1 PF03330.13 EIM90914.1 - 1.2e-06 28.3 1.0 4.5e-06 26.5 0.7 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM90914.1 - 0.00079 19.0 0.1 0.0012 18.5 0.1 1.4 1 1 0 1 1 1 1 Barwin family Svf1 PF08622.5 EIM90915.1 - 6.1e-87 291.6 0.0 7e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like TPR_16 PF13432.1 EIM90916.1 - 3e-13 50.0 3.0 0.0012 19.5 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM90916.1 - 6.2e-13 48.8 3.8 4.1e-05 23.8 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIM90916.1 - 3.8e-11 42.4 0.5 0.0012 18.4 0.0 3.9 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 EIM90916.1 - 6.6e-10 38.7 0.7 0.072 13.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIM90916.1 - 1.3e-09 37.4 0.0 0.0063 16.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM90916.1 - 8.6e-09 35.2 8.6 0.093 13.4 0.1 6.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM90916.1 - 1.1e-08 34.2 0.6 7.5 6.7 0.3 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM90916.1 - 5.6e-07 28.9 0.0 1.2 8.9 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM90916.1 - 0.0011 19.2 4.9 4 8.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM90916.1 - 0.0022 17.6 3.3 4.3 7.3 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Glyoxalase_2 PF12681.2 EIM90916.1 - 0.0027 18.3 0.4 0.38 11.3 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain TPR_15 PF13429.1 EIM90916.1 - 0.0033 16.5 0.0 0.21 10.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EIM90916.1 - 0.004 16.3 0.1 1.6 7.8 0.0 2.6 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_8 PF13181.1 EIM90916.1 - 0.013 15.2 0.0 32 4.6 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIM90916.1 - 0.035 13.9 4.5 0.3 10.9 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIM90916.1 - 0.035 14.2 3.6 0.11 12.6 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.1 EIM90916.1 - 0.053 13.7 1.5 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fis1_TPR_C PF14853.1 EIM90916.1 - 0.074 12.9 0.3 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EIM90916.1 - 1.5 8.8 6.2 25 4.9 0.0 4.1 6 0 0 6 6 5 0 Tetratricopeptide repeat BTB PF00651.26 EIM90917.1 - 0.025 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain DUF2142 PF09913.4 EIM90918.1 - 0.0059 15.3 1.6 0.0072 15.0 1.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) KAR9 PF08580.5 EIM90919.1 - 7.1 4.7 14.7 8.3 4.5 10.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GPI-anchored PF10342.4 EIM90921.1 - 6.6e-06 26.5 0.7 1.1e-05 25.7 0.5 1.4 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.1 EIM90921.1 - 0.66 10.3 6.8 0.43 10.9 3.3 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) zf-CCHC PF00098.18 EIM90922.1 - 1.1e-07 31.4 8.5 0.00024 20.8 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIM90922.1 - 0.018 14.6 7.2 0.36 10.5 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-BED PF02892.10 EIM90922.1 - 0.24 11.1 3.0 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-CCHC_6 PF15288.1 EIM90922.1 - 4.6 7.0 10.5 1.9 8.2 0.4 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIM90922.1 - 7.7 6.1 9.4 18 4.9 0.0 2.9 2 1 0 2 2 2 0 Zinc knuckle Na_Ca_ex PF01699.19 EIM90923.1 - 4.5e-43 146.1 35.2 2.1e-25 88.9 7.0 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MLANA PF14991.1 EIM90923.1 - 0.074 13.0 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A DPBB_1 PF03330.13 EIM90924.1 - 3.6e-05 23.6 0.0 5e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIM90924.1 - 0.0087 15.7 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Barwin family TPK_catalytic PF04263.11 EIM90925.1 - 4.5e-24 84.3 0.0 6.4e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EIM90925.1 - 4.9e-18 64.6 0.2 9e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SRF-TF PF00319.13 EIM90926.1 - 4.6e-19 67.3 0.1 7.6e-19 66.6 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Isochorismatase PF00857.15 EIM90928.1 - 8.7e-13 48.5 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Pkinase PF00069.20 EIM90930.1 - 4.8e-41 140.6 0.0 6.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM90930.1 - 5e-18 65.0 0.0 7.1e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM90930.1 - 0.00093 18.9 4.2 0.0011 18.7 0.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM90930.1 - 0.0017 17.3 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM90930.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIM90930.1 - 0.065 12.5 0.1 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family CbiM PF01891.11 EIM90931.1 - 0.014 15.0 6.4 0.014 15.0 4.4 2.8 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region WD40 PF00400.27 EIM90932.1 - 1.1e-47 158.2 13.2 1.4e-08 34.2 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Glyoxal_oxid_N PF07250.6 EIM90932.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.6 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.1 EIM90932.1 - 0.14 12.4 18.6 5.8 7.3 0.9 5.9 6 0 0 6 6 6 0 PQQ-like domain DUF4613 PF15390.1 EIM90932.1 - 0.19 9.8 0.0 0.27 9.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) F-box-like PF12937.2 EIM90933.1 - 1.7e-07 30.8 0.1 1.7e-07 30.8 0.1 2.6 3 0 0 3 3 3 1 F-box-like zf-RING_5 PF14634.1 EIM90934.1 - 0.037 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EIM90934.1 - 0.15 11.9 0.1 0.37 10.6 0.1 1.7 1 1 0 1 1 1 0 Ring finger domain Cut8_N PF14482.1 EIM90934.1 - 0.87 9.6 8.4 3.8 7.5 0.8 2.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Tetraspannin PF00335.15 EIM90935.1 - 2.5e-09 36.7 15.8 3.6e-09 36.2 10.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1422 PF07226.6 EIM90935.1 - 0.013 15.2 0.6 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) FTR1 PF03239.9 EIM90935.1 - 0.015 14.2 0.4 0.029 13.3 0.3 1.4 1 0 0 1 1 1 0 Iron permease FTR1 family DUF3278 PF11683.3 EIM90935.1 - 0.057 13.4 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) FA_desaturase PF00487.19 EIM90935.1 - 0.21 10.9 3.1 0.34 10.2 2.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase COMPASS-Shg1 PF05205.7 EIM90936.1 - 9.1e-11 41.9 0.3 1.5e-10 41.3 0.2 1.6 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Sigma70_ner PF04546.8 EIM90936.1 - 1.3 8.6 6.4 2.1 7.9 4.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cyanate_lyase PF02560.9 EIM90937.1 - 9.4e-34 114.7 0.0 1.5e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HDOD PF08668.7 EIM90937.1 - 0.14 11.4 0.0 1.8 7.8 0.0 2.0 1 1 1 2 2 2 0 HDOD domain Complex1_LYR PF05347.10 EIM90938.1 - 3.1e-10 39.6 0.1 4.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIM90938.1 - 3e-08 33.7 0.0 6.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIM90938.1 - 1.6e-05 25.3 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like IL10 PF00726.12 EIM90938.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 10 Aldo_ket_red PF00248.16 EIM90939.1 - 8.1e-47 159.3 0.0 9.4e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4604 PF15377.1 EIM90940.1 - 1e-23 84.2 26.4 4.8e-23 82.1 18.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Arv1 PF04161.8 EIM90941.1 - 2.1e-28 99.6 0.0 7.1e-28 97.9 0.0 1.8 1 1 0 1 1 1 1 Arv1-like family Gti1_Pac2 PF09729.4 EIM90942.1 - 3.3e-31 108.4 0.6 7.1e-29 100.8 0.1 3.0 2 1 0 2 2 2 1 Gti1/Pac2 family Cellulase PF00150.13 EIM90943.1 - 2.1e-14 53.3 4.6 3.3e-14 52.7 2.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EIM90945.1 - 1.4e-75 254.6 0.7 2e-75 254.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIM90945.1 - 3.3e-47 159.3 6.8 1.6e-23 83.0 0.1 3.5 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIM90945.1 - 1.8e-34 118.6 1.7 3.3e-34 117.8 1.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIM90945.1 - 8.7e-17 60.2 0.1 9.6e-16 56.9 0.0 2.5 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EIM90945.1 - 1.6e-05 24.2 0.2 8.1e-05 21.9 0.1 1.9 1 1 0 1 1 1 1 Beta-galactosidase Amidohydro_2 PF04909.9 EIM90945.1 - 0.057 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase DUF718 PF05336.8 EIM90945.1 - 0.18 11.6 1.1 3.3 7.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF718) Tfb2 PF03849.9 EIM90946.1 - 9.3e-130 432.5 0.0 1.1e-129 432.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EIM90946.1 - 0.00019 21.2 0.0 0.00056 19.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.19 EIM90947.1 - 7.6e-35 120.3 40.3 1.2e-20 73.5 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIM90947.1 - 1.4e-17 63.5 51.0 3.1e-13 49.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM90947.1 - 8.8e-08 30.9 24.8 0.0011 17.4 0.0 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein RRM_6 PF14259.1 EIM90948.1 - 4.7e-06 26.4 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM90948.1 - 0.00015 21.2 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM90948.1 - 0.011 15.5 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stm1_N PF09598.5 EIM90948.1 - 0.71 10.6 9.6 5.3 7.8 2.1 2.4 2 0 0 2 2 2 0 Stm1 SPT2 PF08243.6 EIM90949.1 - 6.9e-15 55.3 8.5 6.9e-15 55.3 5.9 4.6 3 1 0 3 3 3 1 SPT2 chromatin protein MFS_1 PF07690.11 EIM90950.1 - 1.5e-25 89.6 37.3 1.5e-16 60.0 3.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Urease_alpha PF00449.15 EIM90951.1 - 5e-55 184.8 2.2 1e-54 183.8 1.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 EIM90951.1 - 4.1e-52 177.8 3.2 5.8e-52 177.3 2.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_beta PF00699.15 EIM90951.1 - 1.7e-41 140.0 0.4 6e-41 138.3 0.1 2.1 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EIM90951.1 - 3.6e-39 132.7 0.1 1e-38 131.3 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EIM90951.1 - 7.6e-06 25.6 3.4 2.1e-05 24.2 2.4 1.8 1 0 0 1 1 1 1 Amidohydrolase EVC2_like PF12297.3 EIM90951.1 - 0.67 8.5 1.5 1 7.9 1.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein MFS_1 PF07690.11 EIM90953.1 - 1.5e-27 96.2 27.0 1.5e-27 96.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM90953.1 - 1.1e-05 24.1 23.6 1.7e-05 23.6 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Cupin_1 PF00190.17 EIM90954.1 - 1.1e-29 102.7 0.0 1e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EIM90954.1 - 1.6e-29 101.2 0.4 2.7e-14 52.4 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EIM90954.1 - 2.5e-09 36.3 0.0 0.00075 18.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EIM90954.1 - 8.6e-07 28.7 0.4 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain ARD PF03079.9 EIM90954.1 - 3.3e-06 27.1 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.13 EIM90954.1 - 1.6e-05 24.5 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EIM90954.1 - 0.00031 20.1 0.0 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 EIM90954.1 - 0.00034 19.9 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein FdtA PF05523.6 EIM90954.1 - 0.0021 17.5 0.0 0.079 12.4 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal Med3 PF11593.3 EIM90954.1 - 2.6 7.1 9.6 4.3 6.4 6.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal A_deaminase PF00962.17 EIM90955.1 - 2e-37 128.8 0.0 2.4e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 EIM90956.1 - 7e-32 110.4 34.3 8.8e-32 110.1 23.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1314 PF07013.6 EIM90957.1 - 0.12 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) DUF4112 PF13430.1 EIM90958.1 - 1.4e-28 98.8 0.1 1.9e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Tubulin PF00091.20 EIM90961.1 - 1.2e-66 224.6 0.0 1.8e-66 224.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIM90961.1 - 1.6e-39 134.7 0.0 2.7e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIM90961.1 - 1.7e-05 24.8 0.1 3.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIM90961.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Response_reg PF00072.19 EIM90962.1 - 3.3e-19 68.9 0.0 2e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIM90962.1 - 3.7e-15 55.6 0.2 1.9e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 EIM90962.1 - 8.8e-15 54.3 0.1 5.1e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EIM90962.1 - 2.1e-07 31.1 0.3 1.9e-05 24.8 0.0 3.6 3 1 0 3 3 3 1 GAF domain GAF_3 PF13492.1 EIM90962.1 - 6e-05 23.1 0.0 0.34 11.0 0.0 2.9 2 1 0 2 2 2 2 GAF domain ChuX_HutX PF06228.8 EIM90962.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX CTP_transf_1 PF01148.15 EIM90963.1 - 5.5e-06 26.2 3.6 5.5e-06 26.2 2.5 3.3 3 1 1 4 4 4 2 Cytidylyltransferase family Alpha_kinase PF02816.13 EIM90964.1 - 6.7e-14 51.9 0.0 8.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family UDG PF03167.14 EIM90965.1 - 3.8e-25 88.1 0.0 5e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Foie-gras_1 PF11817.3 EIM90965.1 - 0.05 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 bZIP_1 PF00170.16 EIM90966.1 - 2.7e-06 27.2 2.9 4.4e-06 26.5 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIM90966.1 - 0.001 18.8 2.3 0.0022 17.7 1.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper WD40_alt PF14077.1 EIM90966.1 - 0.055 13.1 0.7 0.096 12.3 0.5 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif BMFP PF04380.8 EIM90966.1 - 0.27 11.3 3.9 0.49 10.5 2.7 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity Helicase_C_3 PF13625.1 EIM90967.1 - 2.9e-27 94.9 0.2 1.1e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM90967.1 - 5.5e-14 52.4 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIM90967.1 - 7.1e-13 48.0 0.0 1.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM90967.1 - 4.1e-10 39.3 0.1 2.7e-09 36.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 EIM90968.1 - 7.5e-11 41.4 10.1 5.5e-05 22.9 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIM90968.1 - 3.4e-06 26.6 4.9 0.00096 18.8 1.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EIM90968.1 - 5.5e-05 22.7 0.0 9.9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIM90968.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EIM90968.1 - 0.0012 18.5 7.4 0.24 11.1 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIM90968.1 - 0.0064 16.1 8.8 0.23 11.1 0.6 2.5 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIM90968.1 - 0.045 13.8 5.1 0.087 12.8 3.5 1.5 1 0 0 1 1 1 0 DnaJ central domain FliT PF05400.8 EIM90968.1 - 0.54 10.7 3.1 8.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Flagellar protein FliT CCDC-167 PF15188.1 EIM90968.1 - 0.78 9.7 5.9 0.5 10.3 0.2 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Nol1_Nop2_Fmu PF01189.12 EIM90969.1 - 4.1e-24 85.4 0.0 8e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family Cons_hypoth95 PF03602.10 EIM90969.1 - 0.017 14.5 0.1 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EIM90969.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.26 EIM90970.1 - 1.7e-23 82.1 0.8 2.9e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIM90970.1 - 2.4e-20 72.1 0.4 2.7e-18 65.6 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIM90970.1 - 3.3e-11 43.0 16.9 5.5e-11 42.3 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIM90970.1 - 0.022 14.4 7.1 0.19 11.4 1.0 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EIM90970.1 - 0.55 10.6 6.0 1 9.7 4.2 1.4 1 0 0 1 1 1 0 Cytochrome c3 Ras PF00071.17 EIM90972.1 - 5.4e-58 194.9 0.1 6.2e-58 194.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM90972.1 - 6.7e-20 71.7 0.0 9.5e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM90972.1 - 5.3e-09 35.5 0.0 6.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM90972.1 - 2.1e-06 27.3 0.1 4.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM90972.1 - 0.0055 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM90972.1 - 0.012 14.9 0.1 0.027 13.7 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EIM90972.1 - 0.082 12.4 1.5 0.92 8.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 EIM90972.1 - 0.12 11.7 0.2 0.98 8.8 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.8 EIM90972.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase CIA30 PF08547.7 EIM90973.1 - 3.4e-21 75.7 0.0 4.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) MarC PF01914.12 EIM90975.1 - 0.15 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein SAGA-Tad1 PF12767.2 EIM90976.1 - 0.041 13.5 3.0 0.043 13.4 2.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NARP1 PF12569.3 EIM90976.1 - 0.097 11.4 9.3 0.11 11.2 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2413 PF10310.4 EIM90976.1 - 0.17 10.6 10.1 0.2 10.4 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4551 PF15087.1 EIM90976.1 - 0.35 9.1 2.6 0.37 9.0 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DDRGK PF09756.4 EIM90976.1 - 1.5 8.2 15.5 1.7 7.9 10.7 1.2 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.7 EIM90976.1 - 2.3 8.0 10.2 3 7.6 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.4 EIM90976.1 - 2.3 6.9 5.6 2.6 6.7 3.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain YqfQ PF14181.1 EIM90976.1 - 3.1 7.8 9.0 3.9 7.4 6.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein MIP-T3 PF10243.4 EIM90976.1 - 5.5 5.3 21.2 6.4 5.1 14.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rtf2 PF04641.7 EIM90976.1 - 7.1 5.7 12.9 9.6 5.3 8.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Fungal_trans_2 PF11951.3 EIM90977.1 - 0.01 14.4 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF758 PF05527.6 EIM90977.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) DDE_3 PF13358.1 EIM90978.1 - 6.1e-07 29.2 0.0 6.8e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM90979.1 - 4.9e-08 32.8 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2_2 PF14227.1 EIM90981.1 - 3.9e-11 42.5 0.3 1.6e-10 40.5 0.2 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIM90981.1 - 8.3e-08 32.0 0.5 1.1e-06 28.4 0.3 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Phg_2220_C PF09524.5 EIM90981.1 - 0.11 12.5 0.0 1.7 8.7 0.0 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Retrotrans_gag PF03732.12 EIM90983.1 - 9.7e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIM90983.1 - 0.11 12.5 1.0 0.2 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2063 PF09836.4 EIM90984.1 - 0.084 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) DUF658 PF04936.7 EIM90985.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DDE_Tnp_4 PF13359.1 EIM90989.1 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.9 EIM90990.1 - 4.6e-14 51.7 0.1 8.7e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region XH PF03469.9 EIM90990.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 XH domain zf-B_box PF00643.19 EIM90992.1 - 0.13 12.1 4.6 0.28 11.0 3.2 1.5 1 0 0 1 1 1 0 B-box zinc finger Tet_JBP PF12851.2 EIM90993.1 - 2.7e-08 33.3 0.0 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM90993.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 EIM90994.1 - 0.034 13.6 0.2 0.076 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Cauli_VI PF01693.11 EIM90995.1 - 1.6e-15 56.8 0.5 2.1e-05 24.4 0.0 3.7 3 1 0 3 3 3 3 Caulimovirus viroplasmin DUF869 PF05911.6 EIM90995.1 - 2.3 6.3 3.9 3 5.9 2.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) HMG_box PF00505.14 EIM90996.1 - 0.059 13.6 0.5 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Phage_RpbA PF10789.4 EIM90997.1 - 0.0057 16.4 0.7 0.0074 16.1 0.5 1.2 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA NDUFB10 PF10249.4 EIM90997.1 - 0.011 15.8 0.5 0.011 15.8 0.4 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 WD40 PF00400.27 EIM90999.1 - 2.5e-25 87.3 0.3 4.4e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat RNA_pol_Rpb5_C PF01191.14 EIM91000.1 - 4.6e-33 112.6 0.5 6.9e-33 112.0 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EIM91000.1 - 9.1e-18 64.4 0.0 1.6e-17 63.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain PDEase_I PF00233.14 EIM91000.1 - 0.029 14.1 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Terpene_synth_C PF03936.11 EIM91001.1 - 5e-11 42.3 1.9 8.5e-11 41.5 0.7 1.7 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Pyr_redox_2 PF07992.9 EIM91002.1 - 5.2e-29 101.5 0.0 9.6e-29 100.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EIM91002.1 - 2.9e-16 58.8 0.1 7.2e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EIM91002.1 - 1.1e-13 51.7 0.2 1.9e-06 28.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM91002.1 - 2e-11 44.1 1.6 1.9e-08 34.5 0.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EIM91002.1 - 2.1e-07 31.1 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EIM91002.1 - 5.7e-06 25.4 0.1 0.0081 15.1 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIM91002.1 - 4.1e-05 22.6 0.2 0.28 10.0 0.0 3.0 1 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIM91002.1 - 0.0015 17.0 0.1 0.67 8.3 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 EIM91002.1 - 0.0017 18.1 0.1 10 5.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EIM91002.1 - 0.035 14.3 0.2 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Cys_Met_Meta_PP PF01053.15 EIM91003.1 - 2.8e-129 430.7 0.0 3.7e-129 430.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EIM91003.1 - 1e-19 70.3 0.1 1e-18 67.1 0.1 2.8 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIM91003.1 - 1.5e-06 28.2 0.1 6.7e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 GHMP kinases C terminal Aminotran_1_2 PF00155.16 EIM91003.1 - 7.1e-06 25.2 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIM91003.1 - 7.6e-06 25.1 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EIM91003.1 - 0.00026 19.4 0.0 0.00076 17.8 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EIM91003.1 - 0.0029 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GalKase_gal_bdg PF10509.4 EIM91003.1 - 0.004 16.3 0.0 0.0082 15.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF4129 PF13559.1 EIM91003.1 - 0.033 14.1 0.2 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) GDC-P PF02347.11 EIM91003.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein zf-HIT PF04438.11 EIM91004.1 - 6.3e-09 35.3 9.0 1e-08 34.6 6.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EIM91004.1 - 5.8 6.8 13.2 9.7 6.1 9.1 1.4 1 0 0 1 1 1 0 MYND finger HMGL-like PF00682.14 EIM91005.1 - 1.6e-70 237.4 1.2 2.3e-70 236.9 0.8 1.2 1 0 0 1 1 1 1 HMGL-like DUF3500 PF12006.3 EIM91005.1 - 0.049 12.5 0.6 0.093 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) ECH PF00378.15 EIM91006.1 - 9e-25 87.2 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sugar_tr PF00083.19 EIM91007.1 - 5.4e-71 239.4 25.1 6.6e-71 239.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM91007.1 - 1.8e-26 92.7 48.6 1.6e-23 83.0 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM91007.1 - 0.002 16.5 1.3 0.002 16.5 0.9 3.3 2 2 0 2 2 2 2 MFS/sugar transport protein Pkinase PF00069.20 EIM91008.1 - 3.4e-57 193.5 0.0 4.9e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91008.1 - 3.6e-18 65.5 0.0 5.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM91008.1 - 0.0036 16.2 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EIM91008.1 - 0.019 14.3 0.7 0.14 11.4 0.4 2.2 1 1 0 1 1 1 0 RIO1 family DUF4599 PF15371.1 EIM91008.1 - 0.12 12.4 0.4 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) PHD PF00628.24 EIM91009.1 - 4.7e-07 29.4 5.1 4.7e-07 29.4 3.5 2.2 1 1 1 2 2 2 1 PHD-finger Peptidase_C98 PF15499.1 EIM91009.1 - 0.02 14.2 0.5 0.023 13.9 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase C1_1 PF00130.17 EIM91009.1 - 0.056 13.1 0.2 0.056 13.1 0.1 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF116 PF01976.12 EIM91009.1 - 9.2 5.7 8.0 0.3 10.5 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF116 MOZ_SAS PF01853.13 EIM91010.1 - 5.6e-72 240.9 0.1 8e-72 240.4 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family GFA PF04828.9 EIM91012.1 - 2.6e-13 49.7 1.2 4.8e-13 48.8 0.9 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EIM91012.1 - 0.037 13.9 2.5 0.094 12.6 1.7 1.6 1 0 0 1 1 1 0 Cysteine-rich CWC zf-LSD1 PF06943.7 EIM91012.1 - 0.51 9.9 3.3 4.2 7.0 0.3 3.0 3 0 0 3 3 3 0 LSD1 zinc finger zf-CSL PF05207.8 EIM91012.1 - 3.4 7.2 6.8 0.39 10.2 1.4 1.8 2 0 0 2 2 2 0 CSL zinc finger DUF1295 PF06966.7 EIM91013.1 - 6.2e-48 163.1 0.2 8.1e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EIM91013.1 - 0.00023 19.8 0.5 0.00051 18.7 0.4 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EIM91013.1 - 0.00047 20.2 0.1 0.0015 18.6 0.0 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIM91013.1 - 0.0016 18.5 1.2 0.0024 17.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EIM91013.1 - 0.01 15.6 0.5 0.017 14.8 0.3 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase HNH_2 PF13391.1 EIM91014.1 - 1.6e-06 27.7 0.1 3.1e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.27 EIM91015.1 - 1e-27 94.9 4.5 6.6e-07 28.9 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EIM91015.1 - 0.012 15.3 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A FA_hydroxylase PF04116.8 EIM91018.1 - 6.3e-13 49.1 30.2 1.3e-12 48.0 17.5 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily RNase_H PF00075.19 EIM91020.1 - 0.00026 21.3 0.3 0.0004 20.7 0.1 1.4 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.22 EIM91021.1 - 0.00071 18.9 0.1 0.00076 18.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIM91023.1 - 0.00065 19.5 1.0 0.00065 19.5 0.7 3.4 5 0 0 5 5 4 1 Zinc knuckle zf-CCHC_5 PF14787.1 EIM91023.1 - 0.021 14.3 1.5 0.021 14.3 1.0 2.6 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 EIM91023.1 - 0.037 13.6 14.7 0.11 12.1 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle DZR PF12773.2 EIM91023.1 - 0.31 10.8 13.7 6.6 6.6 3.1 2.5 1 1 1 2 2 2 0 Double zinc ribbon Prenyltrans PF00432.16 EIM91023.1 - 0.56 9.8 4.4 0.4 10.2 0.2 2.3 1 1 1 2 2 2 0 Prenyltransferase and squalene oxidase repeat zf-B_box PF00643.19 EIM91023.1 - 0.65 9.9 13.6 0.69 9.8 4.0 2.7 1 1 1 2 2 2 0 B-box zinc finger ArfGap PF01412.13 EIM91023.1 - 2.1 8.1 11.7 0.32 10.7 2.9 1.9 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf-CHY PF05495.7 EIM91023.1 - 2.1 8.5 14.0 10 6.3 8.0 2.1 1 1 1 2 2 2 0 CHY zinc finger zf-CCHC_4 PF14392.1 EIM91023.1 - 2.9 7.6 13.0 0.14 11.8 0.7 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-Sec23_Sec24 PF04810.10 EIM91023.1 - 5 6.7 7.2 8.9 5.9 0.2 2.8 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 EIM91023.1 - 7.4 5.9 11.3 0.86 8.8 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 EIM91023.1 - 9.4 5.3 10.2 0.29 10.2 0.3 2.5 1 1 0 2 2 2 0 Mu-like prophage protein Com Asp PF00026.18 EIM91025.1 - 1.7e-61 208.2 6.9 2.1e-61 207.9 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM91025.1 - 1.9e-08 34.4 1.7 2.5e-08 34.0 0.6 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Pkinase PF00069.20 EIM91026.1 - 1.1e-09 37.7 0.0 3.6e-09 36.1 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91026.1 - 0.00053 19.1 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Asp PF00026.18 EIM91027.1 - 5.3e-08 32.4 0.0 6.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease IncA PF04156.9 EIM91027.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein TauD PF02668.11 EIM91028.1 - 2.6e-41 142.0 0.0 4.2e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIM91028.1 - 2.4e-07 31.0 0.0 5.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 EIM91028.1 - 0.0058 15.5 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 CsiD IlvN PF07991.7 EIM91029.1 - 1.3e-46 157.9 0.0 2.4e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EIM91029.1 - 7.6e-42 142.6 0.0 1.1e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EIM91029.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIM91029.1 - 0.21 12.0 0.9 0.47 10.9 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EIM91030.1 - 2.2e-15 56.3 0.0 3.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91030.1 - 3.8e-11 42.7 0.0 7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91030.1 - 0.034 15.0 0.0 0.056 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TFIIA_gamma_N PF02268.11 EIM91030.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Aminotran_3 PF00202.16 EIM91031.1 - 7.7e-42 143.3 0.0 2.3e-40 138.5 0.0 2.5 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EIM91031.1 - 7.8e-29 100.7 0.0 1.5e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sec61_beta PF03911.11 EIM91032.1 - 9.7e-19 66.8 0.3 1.2e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Telomere_Sde2 PF13019.1 EIM91033.1 - 8.6e-52 175.0 0.0 1.2e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF3829 PF12889.2 EIM91033.1 - 0.024 13.8 0.7 0.035 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) GTSE1_N PF15259.1 EIM91033.1 - 0.2 11.6 4.1 0.091 12.7 0.9 1.9 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 Peptidase_M28 PF04389.12 EIM91034.1 - 1.2e-24 87.0 0.1 2.2e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIM91034.1 - 3.4e-06 26.6 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ter PF05472.6 EIM91034.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Peptidase_M28 PF04389.12 EIM91035.1 - 1.6e-25 89.8 0.1 2.6e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIM91035.1 - 2.1e-05 24.0 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Aconitase PF00330.15 EIM91036.1 - 2.2e-69 234.1 0.2 1.6e-38 132.3 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIM91036.1 - 1.7e-20 73.4 0.0 5.3e-20 71.8 0.0 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain UvrD_C PF13361.1 EIM91037.1 - 1.4e-71 241.7 0.0 5.7e-71 239.8 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EIM91037.1 - 1.2e-66 225.1 0.0 4.9e-66 223.1 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EIM91037.1 - 2.2e-14 53.4 0.0 5.2e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EIM91037.1 - 4.9e-14 51.8 0.0 1.5e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EIM91037.1 - 1.5e-08 34.4 0.4 0.0076 15.7 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIM91037.1 - 6.1e-06 25.9 0.0 0.00067 19.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIM91037.1 - 0.0021 17.4 0.0 0.052 12.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Prog_receptor PF02161.10 EIM91037.1 - 0.16 10.7 0.6 0.26 10.0 0.4 1.2 1 0 0 1 1 1 0 Progesterone receptor bZIP_1 PF00170.16 EIM91038.1 - 7.9e-08 32.1 1.8 1.7e-07 31.1 1.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIM91038.1 - 0.0013 18.4 3.6 0.003 17.3 2.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EIM91038.1 - 0.042 12.7 0.3 0.057 12.3 0.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF2205 PF10224.4 EIM91038.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Mto2_bdg PF12808.2 EIM91038.1 - 0.15 12.2 4.6 0.25 11.4 3.2 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40_alt PF14077.1 EIM91038.1 - 0.26 10.9 0.8 0.46 10.1 0.5 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif BMFP PF04380.8 EIM91038.1 - 0.4 10.8 3.4 1.2 9.3 2.5 1.6 2 0 0 2 2 2 0 Membrane fusogenic activity DUF605 PF04652.11 EIM91038.1 - 1.6 8.0 14.1 1.9 7.8 9.7 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EIM91038.1 - 2.9 6.0 20.3 3 5.9 14.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2360 PF10152.4 EIM91038.1 - 9.7 6.4 10.2 16 5.7 7.1 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) HSP20 PF00011.16 EIM91039.1 - 6e-10 38.9 0.0 8.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BTB PF00651.26 EIM91041.1 - 3.8e-06 26.8 0.1 1.4e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain tRNA-synt_1g PF09334.6 EIM91042.1 - 9.9e-128 426.1 0.0 1.3e-127 425.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EIM91042.1 - 1.1e-07 31.6 0.1 9.7e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA WHEP-TRS PF00458.15 EIM91042.1 - 8.9e-07 28.4 2.4 2.5e-06 27.0 1.7 1.7 1 0 0 1 1 1 1 WHEP-TRS domain DUF3323 PF11796.3 EIM91042.1 - 0.13 11.5 4.6 0.21 10.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) C1_1 PF00130.17 EIM91042.1 - 0.17 11.6 2.3 0.65 9.7 1.6 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EIM91042.1 - 2 8.3 10.9 9 6.2 7.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon adh_short PF00106.20 EIM91043.1 - 1.1e-24 87.2 0.2 1.5e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM91043.1 - 9.3e-23 81.2 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM91043.1 - 6.8e-13 48.6 0.1 1.1e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 KR domain SH3_9 PF14604.1 EIM91044.1 - 2.5e-14 52.5 0.2 3.8e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM91044.1 - 3.8e-14 51.7 0.3 5.8e-14 51.2 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIM91044.1 - 2.3e-13 49.3 0.0 3.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.6 EIM91044.1 - 2.9 7.1 6.6 0.5 9.6 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.11 EIM91045.1 - 3.8e-34 117.9 34.8 2e-26 92.5 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM91045.1 - 1.6e-08 34.2 7.1 0.0029 17.3 0.3 3.7 4 0 0 4 4 4 3 MFS_1 like family Gti1_Pac2 PF09729.4 EIM91046.1 - 0.056 13.3 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family MARVEL PF01284.18 EIM91048.1 - 3.9e-11 42.9 11.4 5.8e-11 42.3 7.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain MFS_2 PF13347.1 EIM91048.1 - 2.1 6.6 11.8 1.1 7.5 5.9 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein Mnd1 PF03962.10 EIM91049.1 - 2.6 7.6 9.4 2 8.0 0.9 2.4 2 0 0 2 2 2 0 Mnd1 family NUDIX PF00293.23 EIM91050.1 - 4.4e-16 58.7 0.0 7.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Lipase_GDSL PF00657.17 EIM91051.1 - 7.3e-14 52.1 2.9 9e-14 51.8 2.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIM91051.1 - 4.3e-09 36.7 5.7 6e-09 36.2 4.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family polyprenyl_synt PF00348.12 EIM91052.1 - 8.1e-47 159.2 0.0 1.1e-23 83.4 0.0 2.0 1 1 1 2 2 2 2 Polyprenyl synthetase Terpene_synth_C PF03936.11 EIM91053.1 - 4.1e-15 55.7 0.1 5.6e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain S_tail_recep_bd PF14928.1 EIM91053.1 - 0.031 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain DEAD PF00270.24 EIM91054.1 - 2.3e-48 163.8 0.0 6.7e-47 159.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM91054.1 - 7.4e-28 96.2 0.0 1.7e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM91054.1 - 7.2e-06 25.9 0.0 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIM91054.1 - 0.017 14.7 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EIM91054.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 EIM91054.1 - 0.078 11.3 0.0 0.31 9.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) GRP PF07172.6 EIM91054.1 - 0.13 12.7 33.5 0.32 11.4 23.2 1.6 1 0 0 1 1 1 0 Glycine rich protein family P34-Arc PF04045.9 EIM91056.1 - 9.1e-105 349.2 0.2 1.1e-104 349.0 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF4313 PF14190.1 EIM91056.1 - 0.085 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) RRM_1 PF00076.17 EIM91057.1 - 5.5e-14 51.5 0.1 1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM91057.1 - 7.7e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM91057.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT_2 PF13813.1 EIM91058.1 - 1.4e-16 60.3 3.1 6.3e-16 58.2 0.2 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family EIIC-GAT PF03611.9 EIM91058.1 - 0.0077 15.0 1.0 0.0077 15.0 0.7 2.0 2 0 0 2 2 2 1 PTS system sugar-specific permease component Ras PF00071.17 EIM91059.1 - 3.7e-49 166.2 0.1 4.2e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM91059.1 - 7.2e-22 78.1 0.0 1.1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM91059.1 - 4.3e-08 32.6 0.0 5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM91059.1 - 4.8e-06 26.1 0.0 1.4e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM91059.1 - 0.00022 21.1 0.1 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM91059.1 - 0.0093 15.2 0.1 0.034 13.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ImcF-related_N PF14331.1 EIM91059.1 - 0.036 12.9 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF258 PF03193.11 EIM91059.1 - 0.066 12.4 0.0 0.18 11.0 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 EIM91059.1 - 0.086 11.8 0.1 0.86 8.5 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 EIM91059.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain FtsZ_C PF12327.3 EIM91059.1 - 0.11 12.6 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 FtsZ family, C-terminal domain AAA_16 PF13191.1 EIM91059.1 - 0.18 11.7 0.5 0.37 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.16 EIM91060.1 - 1.5e-41 142.2 0.0 1.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.17 EIM91061.1 - 4.5e-67 226.5 0.0 1.6e-66 224.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.13 EIM91063.1 - 6.8e-09 35.4 13.2 1.3e-08 34.5 9.1 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM91063.1 - 2.8 7.8 6.8 7.1 6.5 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 YlaH PF14036.1 EIM91065.1 - 0.47 10.5 7.7 1.2 9.2 5.4 1.7 1 0 0 1 1 1 0 YlaH-like protein NAPRTase PF04095.11 EIM91066.1 - 4e-55 186.7 0.0 5.3e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_4 PF02390.12 EIM91067.1 - 4.3e-51 172.7 0.0 1.3e-49 167.9 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIM91067.1 - 7.8e-06 26.4 0.0 1.6e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91067.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91067.1 - 0.019 15.2 0.0 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91067.1 - 0.032 14.6 0.0 0.09 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Thaumatin PF00314.12 EIM91068.1 - 5.8e-18 65.1 9.2 9.4e-18 64.4 2.4 2.0 1 1 1 2 2 2 2 Thaumatin family DnaJ PF00226.26 EIM91069.1 - 2.4e-16 59.1 0.8 2.4e-16 59.1 0.5 2.0 2 1 0 2 2 2 1 DnaJ domain DUF1767 PF08585.7 EIM91070.1 - 4.5e-07 30.0 0.0 6.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DUF3349 PF11829.3 EIM91070.1 - 0.09 13.2 0.2 15 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Carn_acyltransf PF00755.15 EIM91071.1 - 6.6e-122 407.5 0.0 1.1e-121 406.7 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_12 PF13087.1 EIM91072.1 - 1.3e-26 93.2 0.0 1.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM91072.1 - 1.6e-10 40.9 0.2 6.3e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIM91072.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EIM91072.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_12 PF13087.1 EIM91074.1 - 1.4e-26 93.1 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIM91074.1 - 1e-08 35.0 0.3 5.6e-08 32.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EIM91074.1 - 3.8e-05 23.3 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIM91074.1 - 0.0059 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaJ PF00226.26 EIM91075.1 - 9.1e-06 25.3 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EIM91075.1 - 0.00033 20.4 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 NmrA PF05368.8 EIM91076.1 - 2.9e-33 115.0 0.0 4.4e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM91076.1 - 4e-05 23.6 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Abhydrolase_3 PF07859.8 EIM91077.1 - 2.5e-35 121.9 0.0 2.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF515 PF04415.7 EIM91078.1 - 0.76 7.9 11.6 0.85 7.7 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_viral_N PF00242.12 EIM91078.1 - 0.82 8.6 8.6 1.1 8.1 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EIM91078.1 - 3.7 5.7 9.7 4.2 5.5 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Pcc1 PF09341.5 EIM91080.1 - 1.9e-18 66.2 0.2 2.1e-18 66.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_M24 PF00557.19 EIM91081.1 - 4.6e-26 91.6 0.1 6e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TyeA PF09059.5 EIM91081.1 - 0.081 12.8 0.3 15 5.6 0.0 2.4 2 0 0 2 2 2 0 TyeA GnsAB PF08178.6 EIM91081.1 - 3.7 7.2 7.8 12 5.5 0.1 2.8 2 1 0 2 2 2 0 GnsA/GnsB family Methyltransf_11 PF08241.7 EIM91082.1 - 6.6e-13 48.9 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91082.1 - 3e-11 43.8 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91082.1 - 4.9e-09 36.1 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM91082.1 - 3e-08 33.0 0.0 4.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIM91082.1 - 9.4e-08 32.3 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91082.1 - 2.7e-07 30.6 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91082.1 - 5.5e-07 29.9 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91082.1 - 7.1e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM91082.1 - 0.00017 21.0 0.0 0.00058 19.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIM91082.1 - 0.00033 19.7 0.0 0.0015 17.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EIM91082.1 - 0.00089 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EIM91082.1 - 0.021 14.2 0.0 0.074 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 EIM91082.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EIM91082.1 - 0.028 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EIM91082.1 - 0.08 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EIM91082.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CMAS PF02353.15 EIM91082.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NDUF_B8 PF05821.6 EIM91083.1 - 1.7e-05 24.5 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) XPG_N PF00752.12 EIM91084.1 - 2.3e-30 104.8 0.0 5.4e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIM91084.1 - 2.6e-25 88.2 0.0 6.6e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIM91084.1 - 0.002 17.6 0.0 0.005 16.3 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EIM91084.1 - 0.028 14.6 0.2 0.21 11.8 0.0 2.5 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 EIM91084.1 - 4.3 7.1 10.3 2.8 7.7 1.0 3.1 1 1 1 2 2 2 0 Ubiquitin interaction motif EI24 PF07264.6 EIM91086.1 - 0.021 14.2 0.2 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Nucleoplasmin PF03066.10 EIM91088.1 - 3.5 7.1 17.0 4.6 6.7 3.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin Pkinase PF00069.20 EIM91089.1 - 9.4e-07 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM91089.1 - 0.00092 19.0 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM91089.1 - 0.0028 17.0 0.3 0.0074 15.6 0.1 1.7 2 0 0 2 2 2 1 RIO1 family CtaG_Cox11 PF04442.9 EIM91090.1 - 2.1e-56 189.9 0.0 2.6e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 ING PF12998.2 EIM91091.1 - 2.8e-13 50.0 0.8 4.5e-13 49.3 0.6 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIM91091.1 - 1.8e-08 33.9 7.9 2.7e-08 33.3 5.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIM91091.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain FlgN PF05130.7 EIM91091.1 - 0.0098 16.1 2.5 2 8.6 0.4 2.3 2 0 0 2 2 2 2 FlgN protein DUF4552 PF15089.1 EIM91091.1 - 0.054 12.3 0.3 0.075 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Lipase_GDSL PF00657.17 EIM91092.1 - 1.1e-13 51.6 2.3 1.4e-13 51.2 1.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIM91092.1 - 5.1e-11 43.0 4.0 6.9e-11 42.5 2.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Endonuclease_7 PF02945.10 EIM91092.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII Phosphonate-bd PF12974.2 EIM91093.1 - 1.3e-06 27.9 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EIM91093.1 - 1.4e-05 24.7 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EIM91093.1 - 0.0004 19.7 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 EIM91093.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family LysR_substrate PF03466.15 EIM91093.1 - 0.12 11.5 0.0 0.43 9.6 0.0 1.9 1 1 0 1 1 1 0 LysR substrate binding domain Auxin_repressed PF05564.7 EIM91094.1 - 3.4 8.2 7.3 4.6 7.8 5.0 1.4 1 1 0 1 1 1 0 Dormancy/auxin associated protein TPR_11 PF13414.1 EIM91096.1 - 5.6e-12 45.1 8.0 7.1e-07 28.7 1.2 2.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIM91096.1 - 6.4e-08 31.9 3.8 0.1 12.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91096.1 - 1.2e-07 31.7 0.1 0.00026 21.3 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91096.1 - 8.5e-07 29.2 2.7 1.8e-06 28.1 0.1 2.6 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91096.1 - 1.4e-05 24.4 6.5 0.0085 15.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIM91096.1 - 1.6e-05 24.9 1.3 0.013 15.6 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIM91096.1 - 5.3e-05 23.7 1.1 0.03 14.9 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91096.1 - 9.4e-05 21.9 0.1 0.81 9.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91096.1 - 0.0013 18.7 1.6 0.0067 16.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM91096.1 - 0.0018 18.1 0.3 0.0046 16.7 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR_3 PF13812.1 EIM91096.1 - 0.0019 18.3 0.1 3.1 8.3 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_6 PF13174.1 EIM91096.1 - 0.0034 17.7 3.4 0.23 12.0 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIM91096.1 - 0.0038 17.3 3.0 0.0058 16.7 0.3 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EIM91096.1 - 0.02 14.8 4.1 0.04 13.8 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ProQ PF04352.8 EIM91096.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.0 2 0 0 2 2 2 0 ProQ/FINO family Di19_C PF14571.1 EIM91096.1 - 0.072 13.4 0.5 0.25 11.6 0.0 2.0 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Fis1_TPR_C PF14853.1 EIM91096.1 - 0.08 12.8 0.2 1.2 9.0 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EIM91096.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IQ-like PF15157.1 EIM91097.1 - 0.018 15.2 0.8 0.087 13.0 0.2 2.4 3 0 0 3 3 3 0 IQ-like Fumble PF03630.9 EIM91102.1 - 0.1 11.4 0.0 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Fumble Acyl-CoA_dh_1 PF00441.19 EIM91103.1 - 2.1e-30 105.7 1.0 3.2e-30 105.1 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIM91103.1 - 9e-19 66.7 0.4 1.9e-18 65.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIM91103.1 - 4.4e-17 61.6 0.0 1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EIM91103.1 - 1.2e-12 48.4 0.1 7.7e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIM91103.1 - 1e-05 25.8 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EIM91104.1 - 5.5e-07 28.9 0.0 9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM91104.1 - 0.00051 19.4 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM91104.1 - 0.035 13.8 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIM91104.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box PF00646.28 EIM91105.1 - 5e-07 29.2 0.0 1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM91105.1 - 0.0082 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like Actin PF00022.14 EIM91106.1 - 1.7e-45 155.1 0.0 2.4e-38 131.5 0.0 3.1 3 0 0 3 3 3 3 Actin Arrestin_N PF00339.24 EIM91107.1 - 0.00053 19.8 1.1 0.011 15.5 0.3 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIM91107.1 - 0.029 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Pyrophosphatase PF00719.14 EIM91108.1 - 1.2e-34 118.9 0.0 1.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Methyltransf_16 PF10294.4 EIM91109.1 - 2.4e-19 69.4 0.0 3.4e-18 65.6 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Cellulase PF00150.13 EIM91110.1 - 2.7e-19 69.4 0.0 3.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIM91110.1 - 0.00018 21.8 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Na_H_Exchanger PF00999.16 EIM91111.1 - 1.1e-34 119.6 40.8 4.9e-34 117.4 28.3 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Fig1 PF12351.3 EIM91111.1 - 4.1 7.2 9.6 0.17 11.7 1.0 2.4 1 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 GMC_oxred_C PF05199.8 EIM91112.1 - 4.7e-05 23.7 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase ABC_membrane PF00664.18 EIM91113.1 - 3.4e-59 200.5 34.2 1.7e-30 106.3 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM91113.1 - 9.4e-52 174.9 0.1 6.2e-27 94.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EIM91113.1 - 8e-11 42.4 0.1 0.091 12.7 0.0 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EIM91113.1 - 3.3e-10 39.5 1.2 0.0036 16.5 0.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM91113.1 - 7.8e-06 25.4 0.2 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM91113.1 - 1e-05 24.9 1.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIM91113.1 - 2e-05 25.0 2.4 0.012 15.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EIM91113.1 - 4.3e-05 23.4 1.2 0.1 12.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIM91113.1 - 7.7e-05 23.1 1.2 0.36 11.3 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EIM91113.1 - 7.7e-05 22.7 0.2 0.021 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 EIM91113.1 - 0.0001 21.8 0.1 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EIM91113.1 - 0.00078 18.6 1.4 0.06 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EIM91113.1 - 0.0019 17.9 1.6 0.073 12.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM91113.1 - 0.0022 18.7 0.0 4 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EIM91113.1 - 0.0093 14.4 0.0 0.017 13.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EIM91113.1 - 0.012 15.4 2.5 1.4 8.6 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Zeta_toxin PF06414.7 EIM91113.1 - 0.012 14.6 2.1 0.54 9.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 EIM91113.1 - 0.013 14.9 1.5 0.053 12.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EIM91113.1 - 0.013 15.0 1.8 1.3 8.5 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EIM91113.1 - 0.014 14.0 2.4 2 6.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EIM91113.1 - 0.016 14.9 0.3 0.098 12.3 0.0 2.4 3 0 0 3 3 2 0 Archaeal ATPase AAA_22 PF13401.1 EIM91113.1 - 0.016 15.3 4.2 0.61 10.2 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EIM91113.1 - 0.018 14.0 0.1 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EIM91113.1 - 0.031 13.7 0.8 0.82 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EIM91113.1 - 0.032 14.1 1.0 15 5.5 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIM91113.1 - 0.034 14.4 0.2 8.8 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIM91113.1 - 0.054 13.0 2.7 4 6.9 0.1 3.3 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.1 EIM91113.1 - 0.067 12.9 0.8 0.48 10.2 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EIM91113.1 - 0.068 12.6 0.2 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EIM91113.1 - 0.07 12.0 0.1 7 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4349 PF14257.1 EIM91113.1 - 0.081 12.1 1.3 0.23 10.6 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA PF00004.24 EIM91113.1 - 0.082 13.1 0.6 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIM91113.1 - 0.12 12.2 0.9 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain RecA PF00154.16 EIM91113.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NACHT PF05729.7 EIM91113.1 - 0.13 11.8 0.9 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 EIM91113.1 - 0.16 11.8 7.1 0.41 10.4 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EIM91113.1 - 0.22 11.0 1.0 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PSDC PF12588.3 EIM91114.1 - 1.1e-42 145.0 0.0 2.4e-42 143.8 0.0 1.5 2 0 0 2 2 2 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EIM91114.1 - 2.2e-39 134.8 0.0 2.9e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EIM91114.1 - 0.025 14.2 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EIM91114.1 - 0.066 12.8 0.2 0.69 9.6 0.1 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EIM91114.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M23 DUF2852 PF11014.3 EIM91115.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) TSP9 PF11493.3 EIM91115.1 - 0.16 12.5 0.1 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 TRP PF06011.7 EIM91115.1 - 0.29 9.6 3.6 0.5 8.8 2.5 1.3 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Actin PF00022.14 EIM91116.1 - 8e-88 294.4 0.0 1.1e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Actin TPR_2 PF07719.12 EIM91117.1 - 7e-30 100.5 2.7 5.8e-05 22.7 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91117.1 - 4.4e-28 96.7 2.1 3.3e-12 45.8 0.0 6.8 6 1 1 7 7 7 4 TPR repeat TPR_1 PF00515.23 EIM91117.1 - 8.5e-26 88.4 3.3 2.1e-07 30.2 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EIM91117.1 - 5.9e-23 80.8 1.7 3.5e-08 33.4 0.0 5.0 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIM91117.1 - 1.4e-22 79.4 9.3 2.4e-11 43.3 0.0 8.0 7 2 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIM91117.1 - 7.5e-16 56.6 0.0 0.00015 21.2 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91117.1 - 2.8e-11 43.5 0.2 0.0027 18.0 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIM91117.1 - 8.6e-11 41.4 12.2 0.0009 19.0 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91117.1 - 1e-10 41.9 12.2 0.0038 17.8 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91117.1 - 3.5e-10 39.2 0.2 1.7 9.0 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91117.1 - 4.3e-09 36.2 9.2 0.16 12.6 0.0 8.6 6 2 4 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91117.1 - 1.3e-07 30.8 5.7 0.3 10.9 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIM91117.1 - 3.2e-07 30.3 8.5 0.029 14.8 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIM91117.1 - 0.0011 19.1 4.3 2 9.1 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.1 EIM91117.1 - 0.017 14.3 0.3 0.16 11.1 0.2 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 EIM91117.1 - 0.034 13.9 0.7 27 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 EIM91117.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 EIM91117.1 - 1.8 8.4 14.2 11 6.0 0.0 5.7 6 1 1 8 8 6 0 Tetratricopeptide repeat DUF3494 PF11999.3 EIM91118.1 - 4.3e-49 166.9 16.8 1.1e-48 165.5 11.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) RD3 PF14473.1 EIM91119.1 - 0.04 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 RD3 protein K167R PF08065.7 EIM91119.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 K167R (NUC007) repeat RRM_1 PF00076.17 EIM91120.1 - 8.7e-15 54.1 0.0 1.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM91120.1 - 3.4e-11 42.9 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM91120.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_18 PF08087.6 EIM91121.1 - 0.067 12.9 0.5 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily Complex1_LYR_1 PF13232.1 EIM91124.1 - 1e-12 48.0 0.5 1.7e-12 47.3 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIM91124.1 - 1.6e-12 47.0 0.2 1.6e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EIM91124.1 - 0.00063 20.1 0.2 0.00079 19.8 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sugar_tr PF00083.19 EIM91125.1 - 2.1e-47 161.7 26.9 2.5e-47 161.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM91125.1 - 3.7e-19 68.6 29.4 3.7e-19 68.6 20.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3087 PF11286.3 EIM91125.1 - 0.15 11.2 0.0 0.36 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF1206 PF06724.6 EIM91125.1 - 6.4 6.6 17.2 0.11 12.3 0.6 4.2 3 2 1 4 4 4 0 Domain of Unknown Function (DUF1206) Acetyltransf_7 PF13508.1 EIM91126.1 - 6.7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM91126.1 - 0.00012 21.9 0.0 0.00098 18.9 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM91126.1 - 0.0014 18.5 0.1 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3494 PF11999.3 EIM91127.1 - 1.7e-54 184.5 14.4 2e-54 184.3 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) PSCyt3 PF07627.6 EIM91129.1 - 0.32 10.8 0.1 0.32 10.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) zf-C2H2_4 PF13894.1 EIM91129.1 - 4.7 7.7 5.8 4.9 7.7 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_2 PF00891.13 EIM91130.1 - 3.3e-24 85.4 0.0 4.8e-22 78.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 EIM91130.1 - 0.0006 20.3 0.0 0.0018 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM91130.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIM91130.1 - 0.0099 15.4 0.0 0.075 12.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91130.1 - 0.012 15.3 0.0 0.055 13.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91130.1 - 0.024 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIM91130.1 - 0.047 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 EIM91130.1 - 0.059 13.8 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EIM91130.1 - 0.095 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RNase_H PF00075.19 EIM91131.1 - 1.4e-10 41.5 0.0 3.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM91131.1 - 4.3e-06 26.9 0.8 1.6e-05 25.1 0.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase XPA_C PF05181.7 EIM91132.1 - 0.00051 19.5 0.1 0.072 12.6 0.0 2.5 2 0 0 2 2 2 2 XPA protein C-terminus Ank_2 PF12796.2 EIM91136.1 - 2.3e-07 31.0 0.1 8.6e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM91136.1 - 0.0034 17.1 0.4 1.3 8.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EIM91136.1 - 0.0038 17.6 0.6 0.12 12.9 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM91136.1 - 0.049 13.8 1.2 16 6.0 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.1 EIM91136.1 - 0.066 13.4 0.2 11 6.4 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) eIF-1a PF01176.14 EIM91137.1 - 3.2e-29 100.1 0.1 4.7e-29 99.6 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ADH_zinc_N PF00107.21 EIM91140.1 - 3.2e-19 68.7 0.0 5.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91140.1 - 9.5e-11 41.4 0.0 3.1e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91140.1 - 0.008 17.0 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PKD_channel PF08016.7 EIM91141.1 - 0.00017 20.1 3.6 0.00017 20.1 2.5 2.4 2 0 0 2 2 2 2 Polycystin cation channel Fmp27_WPPW PF10359.4 EIM91141.1 - 0.11 10.9 0.4 0.16 10.3 0.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Pkinase PF00069.20 EIM91142.1 - 1.5e-58 197.9 0.0 2e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91142.1 - 1.9e-30 105.8 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM91142.1 - 4.2e-07 29.2 0.0 6.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM91142.1 - 0.012 14.6 0.3 0.022 13.8 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.1 EIM91145.1 - 0.19 11.7 0.9 3.3 7.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NPR3 PF03666.8 EIM91146.1 - 2e-62 211.2 0.0 3.8e-62 210.2 0.0 1.5 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_25 PF13649.1 EIM91147.1 - 0.00044 20.5 0.0 0.0012 19.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91147.1 - 0.0063 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Aldo_ket_red PF00248.16 EIM91148.1 - 5.9e-74 248.4 0.0 6.7e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SART-1 PF03343.8 EIM91150.1 - 6.4e-125 417.8 55.9 6.4e-125 417.8 38.8 1.5 2 0 0 2 2 2 1 SART-1 family ABC_trans_N PF14510.1 EIM91150.1 - 0.52 10.4 6.3 5.6 7.1 0.0 3.4 3 0 0 3 3 3 0 ABC-transporter extracellular N-terminal Macro PF01661.16 EIM91151.1 - 6.2e-44 148.6 0.1 8.3e-44 148.2 0.0 1.2 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.19 EIM91152.1 - 1.1e-95 320.9 20.9 1.3e-95 320.6 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM91152.1 - 6.9e-23 80.9 30.5 6.9e-23 80.9 21.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily HPP PF04982.8 EIM91152.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.2 2 2 0 3 3 3 0 HPP family adh_short PF00106.20 EIM91153.1 - 3.6e-24 85.5 5.5 8.4e-24 84.3 3.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM91153.1 - 1.4e-17 64.2 4.1 3.8e-17 62.8 2.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM91153.1 - 2.7e-09 36.9 4.0 4.9e-09 36.1 2.8 1.3 1 0 0 1 1 1 1 KR domain Acyl-CoA_dh_1 PF00441.19 EIM91154.1 - 3.9e-31 108.1 2.0 6.2e-31 107.5 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIM91154.1 - 5.2e-20 70.6 0.4 1.3e-19 69.3 0.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIM91154.1 - 8.8e-15 54.2 0.0 2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EIM91154.1 - 1.4e-14 54.6 0.0 3.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIM91154.1 - 0.00013 22.2 0.3 0.00025 21.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COLFI PF01410.13 EIM91154.1 - 0.037 13.4 1.4 0.12 11.7 0.3 2.0 2 0 0 2 2 2 0 Fibrillar collagen C-terminal domain PHD PF00628.24 EIM91155.1 - 4.5e-08 32.6 10.0 8.4e-08 31.7 6.9 1.5 1 0 0 1 1 1 1 PHD-finger Mem_trans PF03547.13 EIM91155.1 - 0.0016 16.8 0.3 0.0029 15.9 0.2 1.4 1 0 0 1 1 1 1 Membrane transport protein FadA PF09403.5 EIM91156.1 - 0.058 13.4 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA BTB PF00651.26 EIM91157.1 - 2.2e-06 27.6 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain RAB3GAP2_C PF14656.1 EIM91157.1 - 0.058 11.5 0.1 0.073 11.1 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus SinI PF08671.5 EIM91157.1 - 0.13 11.7 0.1 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Anti-repressor SinI Abhydrolase_6 PF12697.2 EIM91159.1 - 7.7e-10 39.0 0.1 1.4e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM91159.1 - 4.5e-09 36.2 0.0 8.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PEP_mutase PF13714.1 EIM91160.1 - 5.5e-44 150.1 0.8 6.5e-44 149.9 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EIM91160.1 - 8.8e-21 73.7 0.6 1.2e-20 73.2 0.4 1.2 1 0 0 1 1 1 1 Isocitrate lyase family TPR_12 PF13424.1 EIM91160.1 - 0.13 12.2 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LysM PF01476.15 EIM91161.1 - 3.9e-05 23.4 0.0 9.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 LysM domain Metallophos_2 PF12850.2 EIM91162.1 - 0.00063 19.6 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIM91162.1 - 0.029 13.7 0.2 0.073 12.4 0.1 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Bac_rhamnosid PF05592.6 EIM91163.1 - 4.2e-34 117.6 0.1 1.6e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EIM91163.1 - 0.005 15.6 0.6 0.0081 14.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 EIM91163.1 - 0.042 12.4 0.2 0.064 11.8 0.1 1.2 1 0 0 1 1 1 0 Trehalase DUF2392 PF10288.4 EIM91164.1 - 1.5e-08 34.9 0.0 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) zf-C3HC4_3 PF13920.1 EIM91164.1 - 1.8 8.2 8.1 0.52 10.0 0.3 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EIM91164.1 - 6.4 6.6 11.4 15 5.4 0.7 2.9 2 2 0 2 2 2 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EIM91164.1 - 8.7 6.0 7.6 5.4 6.7 0.3 3.0 3 1 0 3 3 3 0 Cytochrome c7 RVT_1 PF00078.22 EIM91165.1 - 0.00071 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIM91166.1 - 5.7e-11 42.8 0.0 6.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIM91167.1 - 0.00022 21.4 0.3 0.00055 20.1 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EIM91167.1 - 0.0027 18.0 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 RNase H rve PF00665.21 EIM91169.1 - 2.3e-20 72.8 0.1 3.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIM91169.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Integrase core domain DDE_3 PF13358.1 EIM91170.1 - 0.004 16.9 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIM91171.1 - 1.9e-08 34.1 0.0 9.4e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease SAP PF02037.22 EIM91171.1 - 0.13 11.8 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 SAP domain Bromo_TP PF07524.8 EIM91171.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Mito_fiss_reg PF05308.6 EIM91172.1 - 0.048 13.0 2.1 0.079 12.3 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3426 PF11906.3 EIM91173.1 - 0.12 11.9 0.1 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) PRP1_N PF06424.7 EIM91173.1 - 1.9 8.7 5.5 4.1 7.7 3.9 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal F-box-like PF12937.2 EIM91175.1 - 2e-11 43.4 2.0 2e-11 43.4 1.4 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM91175.1 - 1.4e-07 30.9 0.7 1.4e-07 30.9 0.5 2.1 2 0 0 2 2 2 1 F-box domain CAF1-p150_N PF15557.1 EIM91175.1 - 0.038 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA F-box-like PF12937.2 EIM91176.1 - 6e-14 51.5 0.4 1.2e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91176.1 - 2.3e-05 23.8 0.0 8.7e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EIM91176.1 - 0.0025 17.5 0.2 0.29 10.9 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EIM91176.1 - 0.12 11.9 4.8 3.5 7.3 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LEDGF PF11467.3 EIM91176.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) LRR_1 PF00560.28 EIM91176.1 - 0.99 9.6 2.9 10 6.6 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EIM91176.1 - 1.4 9.4 5.8 18 6.0 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat Peptidase_A21 PF03566.8 EIM91177.1 - 7.5 4.5 14.5 9.3 4.1 10.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 YchF-GTPase_C PF06071.8 EIM91178.1 - 1.5e-35 120.7 0.0 3.8e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EIM91178.1 - 4e-15 55.7 0.0 1.3e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM91178.1 - 1e-05 24.8 0.0 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EIM91178.1 - 0.0099 16.6 0.0 0.041 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 EIM91178.1 - 0.041 12.6 0.4 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EIM91178.1 - 0.12 12.1 0.3 0.68 9.7 0.1 2.3 1 1 2 3 3 3 0 Dynamin family AAA-ATPase_like PF09820.4 EIM91179.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase MBOAT_2 PF13813.1 EIM91180.1 - 1.1e-09 38.1 1.9 1.1e-09 38.1 1.3 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family UPF0016 PF01169.14 EIM91183.1 - 5.5e-45 151.3 18.3 1.3e-22 79.6 5.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4131 PF13567.1 EIM91183.1 - 0.0075 15.6 1.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) TerC PF03741.11 EIM91183.1 - 0.9 8.9 8.1 0.2 11.0 0.6 2.6 2 1 0 2 2 2 0 Integral membrane protein TerC family PITH PF06201.8 EIM91184.1 - 4.3e-41 140.1 0.0 5.6e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain Op_neuropeptide PF08035.6 EIM91184.1 - 0.0099 15.4 0.1 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 Opioids neuropeptide UBX PF00789.15 EIM91185.1 - 2.9e-11 43.2 0.2 5.3e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 UBX domain Peptidase_C2 PF00648.16 EIM91186.1 - 1.8e-63 214.3 6.0 5.6e-42 143.7 0.6 2.1 1 1 1 2 2 2 2 Calpain family cysteine protease TSP_3 PF02412.13 EIM91186.1 - 0.18 11.2 1.9 0.42 10.1 1.3 1.5 1 0 0 1 1 1 0 Thrombospondin type 3 repeat DUF1183 PF06682.7 EIM91188.1 - 8.8e-69 232.5 3.3 1.7e-68 231.6 2.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) RIC3 PF15361.1 EIM91188.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Sugar_tr PF00083.19 EIM91189.1 - 5.6e-119 397.6 27.8 7.6e-119 397.2 19.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM91189.1 - 1.4e-28 99.6 54.7 3.2e-22 78.7 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM91189.1 - 3.7e-05 22.3 40.3 0.00071 18.0 9.9 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein K_channel_TID PF07941.6 EIM91191.1 - 0.46 10.7 7.0 0.83 9.9 4.9 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.11 EIM91192.1 - 6.3e-14 51.4 16.5 6.3e-14 51.4 11.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PI3K_1B_p101 PF10486.4 EIM91192.1 - 1.6 6.2 5.1 2.5 5.5 3.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit F-box-like PF12937.2 EIM91194.1 - 9e-06 25.3 0.1 2.2e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like Uroplakin_II PF07353.7 EIM91194.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Uroplakin II ThiF PF00899.16 EIM91195.1 - 2e-46 157.1 0.0 3.2e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EIM91195.1 - 5.2e-27 93.2 0.1 1.3e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EIM91195.1 - 3.5e-09 36.9 0.0 7.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EIM91195.1 - 8e-06 25.9 0.2 0.00015 21.8 0.1 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EIM91195.1 - 0.0043 16.4 0.0 0.0099 15.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EIM91195.1 - 0.024 13.5 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EIM91195.1 - 0.025 14.2 0.1 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIM91195.1 - 0.031 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding APC10 PF03256.11 EIM91196.1 - 8.9e-47 159.1 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EIM91196.1 - 0.00084 19.1 0.0 0.0029 17.4 0.0 1.8 1 1 1 2 2 2 1 F5/8 type C domain ATP-synt_G PF04718.10 EIM91197.1 - 0.052 14.1 0.6 0.33 11.6 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Med4 PF10018.4 EIM91197.1 - 0.074 12.4 4.8 0.068 12.5 0.3 2.6 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Apolipoprotein PF01442.13 EIM91197.1 - 0.11 12.0 6.5 1.6 8.2 0.1 3.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.6 EIM91197.1 - 0.13 12.6 3.8 0.84 10.0 0.1 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal COG5 PF10392.4 EIM91197.1 - 0.77 9.7 5.1 1.2 9.1 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 YtxH PF12732.2 EIM91197.1 - 1.4 9.3 4.5 6.8 7.1 0.1 3.2 3 0 0 3 3 3 0 YtxH-like protein Syntaxin PF00804.20 EIM91197.1 - 2 8.6 6.8 1.1 9.4 0.6 2.5 2 1 0 2 2 2 0 Syntaxin Cytochrom_C_2 PF01322.15 EIM91197.1 - 2.9 8.4 6.2 0.94 10.0 0.2 2.9 4 0 0 4 4 4 0 Cytochrome C' PEX11 PF05648.9 EIM91199.1 - 0.24 10.6 0.8 0.38 9.9 0.1 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_C2 PF00648.16 EIM91200.1 - 4e-61 206.6 2.8 4.9e-41 140.6 0.1 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease HsbA PF12296.3 EIM91201.1 - 0.53 10.1 8.6 0.75 9.6 0.7 3.3 2 1 0 2 2 2 0 Hydrophobic surface binding protein A ADH_zinc_N PF00107.21 EIM91203.1 - 4.1e-12 45.7 0.1 7.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91203.1 - 4.2e-10 39.3 0.0 2.7e-09 36.7 0.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIM91203.1 - 8.9e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM91203.1 - 0.00039 19.7 0.2 0.00059 19.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Fibrillarin PF01269.12 EIM91203.1 - 0.029 13.2 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin AlaDh_PNT_C PF01262.16 EIM91203.1 - 0.1 12.1 2.1 0.1 12.1 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RabGAP-TBC PF00566.13 EIM91204.1 - 3.9e-48 163.7 0.0 5.9e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_76 PF03663.9 EIM91205.1 - 1.3e-31 110.3 13.7 1.9e-31 109.8 9.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EIM91205.1 - 0.0094 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.6 EIM91205.1 - 0.038 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.9 EIM91206.1 - 2.4e-28 99.6 19.4 3.1e-28 99.2 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 OpcA_G6PD_assem PF10128.4 EIM91206.1 - 0.22 10.3 0.9 0.69 8.7 0.1 1.9 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase subunit LRR_4 PF12799.2 EIM91207.1 - 2.2e-05 23.9 0.1 0.29 10.7 0.0 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM91207.1 - 0.0033 17.3 0.1 9.8 6.6 0.0 4.1 3 1 1 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 EIM91207.1 - 0.0052 16.5 0.5 0.042 13.6 0.1 2.4 1 1 1 2 2 2 1 Leucine rich repeat DDE_Tnp_4 PF13359.1 EIM91208.1 - 3.4e-22 78.7 0.0 4.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.1 EIM91209.1 - 0.2 11.8 1.4 0.28 11.3 0.2 1.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF544 PF04424.8 EIM91211.1 - 9.3e-14 51.2 0.0 4.4e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF544) F-box-like PF12937.2 EIM91212.1 - 1.1e-10 41.0 0.4 3e-10 39.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like DMA PF03474.9 EIM91212.1 - 0.035 13.9 0.1 6.2 6.7 0.0 2.7 3 0 0 3 3 3 0 DMRTA motif FMN_dh PF01070.13 EIM91213.1 - 5.6e-105 351.0 0.3 1.1e-104 350.0 0.2 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIM91213.1 - 5.7e-14 51.6 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EIM91213.1 - 4e-06 25.9 1.1 1.9e-05 23.7 0.8 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EIM91213.1 - 6.6e-06 25.2 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EIM91213.1 - 0.00033 19.9 0.9 0.0024 17.0 0.2 2.1 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EIM91213.1 - 0.0033 16.5 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EIM91213.1 - 0.055 12.4 0.1 0.11 11.3 0.1 1.5 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Peptidase_C32 PF05411.7 EIM91213.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Equine arteritis virus putative proteinase Abhydrolase_3 PF07859.8 EIM91214.1 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM91214.1 - 1.1e-11 44.2 4.8 2.1e-11 43.2 3.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM91214.1 - 1.2e-08 34.7 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM91214.1 - 5.9e-05 23.0 0.1 8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EIM91214.1 - 0.01 14.4 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 EIM91214.1 - 0.016 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EIM91214.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PH_6 PF15406.1 EIM91214.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DIOX_N PF14226.1 EIM91215.1 - 3.6e-18 66.1 0.0 5.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM91215.1 - 9.5e-15 54.7 0.0 2.2e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EIM91216.1 - 8.7e-29 100.3 35.2 8.7e-29 100.3 24.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MRP-L46 PF11788.3 EIM91216.1 - 0.023 15.3 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 PspA_IM30 PF04012.7 EIM91216.1 - 0.08 12.2 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF1049 PF06305.6 EIM91216.1 - 0.95 8.9 7.1 5.9 6.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Peptidase_C2 PF00648.16 EIM91217.1 - 1.8e-55 188.0 4.2 7.1e-38 130.2 0.4 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease CFC PF09443.5 EIM91219.1 - 1.3 8.7 5.2 0.32 10.6 1.2 1.8 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Nucleoplasmin PF03066.10 EIM91221.1 - 0.083 12.4 3.2 0.62 9.5 0.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EIM91221.1 - 3.3 8.0 8.7 5.8 7.3 0.1 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EIM91221.1 - 5.3 6.1 12.1 0.76 8.8 0.6 2.5 2 1 0 2 2 2 0 Myc amino-terminal region COX6B PF02297.12 EIM91222.1 - 3.9e-20 71.6 0.2 4.8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EIM91222.1 - 0.031 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Peptidase_C14 PF00656.17 EIM91224.1 - 3.6e-49 167.7 0.1 4.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIM91225.1 - 1.4e-70 237.8 0.1 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain RNase_P_Rpp14 PF01900.14 EIM91227.1 - 1.3e-26 92.5 0.0 1.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Glyco_hydro_43 PF04616.9 EIM91228.1 - 5.8e-27 94.5 0.3 7e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ECR1_N PF14382.1 EIM91228.1 - 0.1 11.8 1.2 1.5 8.1 0.1 3.0 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Aminotran_1_2 PF00155.16 EIM91229.1 - 1.7e-27 96.3 0.0 2.5e-10 39.8 0.0 4.0 3 1 0 3 3 3 3 Aminotransferase class I and II CoA_transf_3 PF02515.12 EIM91230.1 - 4.1e-46 156.6 0.0 5.6e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III TOM13 PF08219.6 EIM91231.1 - 7.1e-15 54.5 1.0 1.3e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Outer membrane protein TOM13 CAF-1_p150 PF11600.3 EIM91231.1 - 0.0015 17.9 11.0 0.0015 17.9 7.6 3.5 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zip PF02535.17 EIM91231.1 - 0.66 8.9 10.8 0.023 13.6 2.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter OmpH PF03938.9 EIM91231.1 - 0.99 9.3 5.1 1.8 8.4 3.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 EIM91231.1 - 2.7 7.8 12.7 6 6.6 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) PAT1 PF09770.4 EIM91231.1 - 2.7 6.1 16.4 0.5 8.5 3.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Aminotran_5 PF00266.14 EIM91233.1 - 2.7e-16 59.3 0.0 2.7e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 EIM91233.1 - 7.4e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EIM91233.1 - 0.02 13.3 0.0 0.056 11.8 0.0 1.6 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EIM91233.1 - 0.026 13.5 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cytochrom_C_2 PF01322.15 EIM91233.1 - 0.099 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C' AIG2 PF06094.7 EIM91234.1 - 1.5e-11 44.7 0.0 1.8e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 AIG2-like family zf-C2H2 PF00096.21 EIM91235.1 - 0.03 14.6 16.1 0.99 9.8 2.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM91235.1 - 0.033 14.5 13.3 2 8.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Terpene_synth_C PF03936.11 EIM91236.1 - 6.3e-14 51.8 0.0 1.1e-13 51.0 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Aldo_ket_red PF00248.16 EIM91237.1 - 1.8e-73 246.8 0.0 2e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 EIM91238.1 - 8.3e-51 172.8 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM91238.1 - 9.9e-29 100.4 0.1 1.6e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIM91238.1 - 2.7e-05 23.2 0.5 5.1e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EIM91238.1 - 0.00027 19.9 0.1 0.00056 18.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM91238.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM91238.1 - 0.0026 16.6 0.3 0.005 15.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIM91238.1 - 0.0041 15.6 0.1 0.0066 14.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIM91238.1 - 0.007 15.4 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EIM91238.1 - 0.0089 15.1 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM91238.1 - 0.0091 16.0 0.4 0.0091 16.0 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EIM91239.1 - 5.7e-32 110.8 34.8 5.7e-32 110.8 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EIM91240.1 - 3e-44 151.3 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM91241.1 - 0.0021 16.6 0.0 0.0022 16.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EIM91242.1 - 1.8e-19 69.9 0.1 4.5e-14 52.2 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EIM91242.1 - 2.5e-06 27.6 0.3 2.5e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EIM91242.1 - 2.9e-05 24.0 0.3 4.7e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EIM91242.1 - 0.00012 21.2 0.3 0.00016 20.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ELFV_dehydrog PF00208.16 EIM91242.1 - 0.00069 19.2 0.1 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 EIM91242.1 - 0.0018 18.3 0.3 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EIM91242.1 - 0.002 18.5 0.3 0.0043 17.4 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EIM91242.1 - 0.0036 16.0 0.1 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EIM91242.1 - 0.0041 16.7 0.1 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIM91242.1 - 0.022 14.2 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 EIM91242.1 - 0.13 12.6 0.7 0.62 10.4 0.5 2.0 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain p450 PF00067.17 EIM91243.1 - 4.3e-64 216.7 0.0 5.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2976 PF11190.3 EIM91243.1 - 0.059 12.8 0.1 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) GMC_oxred_N PF00732.14 EIM91244.1 - 1.2e-67 228.1 0.0 1.5e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM91244.1 - 2e-34 118.9 0.0 3.4e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lipase_GDSL_2 PF13472.1 EIM91244.1 - 0.029 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.14 EIM91245.1 - 8.7e-21 74.3 0.0 2.8e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM91245.1 - 7.2e-12 44.8 0.0 5.9e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIM91245.1 - 2.7e-08 33.0 0.1 4.8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM91245.1 - 3.3e-06 27.0 0.1 9.3e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIM91245.1 - 5.3e-06 25.7 0.7 8.8e-06 25.0 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIM91245.1 - 0.00011 22.1 0.1 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM91245.1 - 0.00016 22.0 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM91245.1 - 0.00026 20.0 0.0 0.2 10.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 EIM91245.1 - 0.0004 19.5 0.0 0.00066 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIM91245.1 - 0.00075 18.0 0.3 0.0014 17.1 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIM91245.1 - 0.0022 16.9 0.6 0.0029 16.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIM91245.1 - 0.07 11.7 0.0 0.21 10.1 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIM91245.1 - 0.077 13.0 0.1 0.21 11.5 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIM91245.1 - 0.1 12.2 0.7 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 EIM91246.1 - 1.7e-23 82.6 1.0 3e-23 81.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EIM91247.1 - 4.5e-75 252.0 0.0 5.1e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EIM91248.1 - 6.9e-68 229.2 0.0 8.7e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 EIM91250.1 - 0.081 13.3 15.5 0.4 11.1 1.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM91250.1 - 0.29 11.5 14.7 8 7.0 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM91250.1 - 0.52 10.6 6.2 0.48 10.8 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EIM91250.1 - 5.9 7.2 5.9 2.7 8.3 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Oest_recep PF02159.10 EIM91252.1 - 0.092 12.8 0.5 0.09 12.9 0.3 1.0 1 0 0 1 1 1 0 Oestrogen receptor DUF2945 PF11160.3 EIM91254.1 - 1.3e-08 34.4 7.4 0.057 13.2 0.2 4.7 3 2 0 3 3 3 2 Protein of unknown function (DUF2945) DUF1918 PF08940.6 EIM91254.1 - 1.6e-06 27.3 0.7 0.0086 15.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1918) DUF3446 PF11928.3 EIM91254.1 - 0.014 15.5 0.9 0.023 14.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) CAML PF14963.1 EIM91254.1 - 0.12 11.7 1.2 0.17 11.1 0.8 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Peptidase_M15 PF01427.12 EIM91254.1 - 0.22 11.1 2.7 10 5.6 0.1 2.9 1 1 2 3 3 3 0 D-ala-D-ala dipeptidase Tetradecapep PF08187.6 EIM91254.1 - 0.26 11.1 3.9 11 6.1 0.2 2.5 2 0 0 2 2 2 0 Myoactive tetradecapeptides family Biotin_lipoyl PF00364.17 EIM91254.1 - 0.43 10.2 2.0 55 3.4 0.0 3.3 4 0 0 4 4 4 0 Biotin-requiring enzyme CsgF PF10614.4 EIM91254.1 - 2.5 8.0 9.2 1.6 8.6 0.4 2.5 3 0 0 3 3 3 0 Type VIII secretion system (T8SS), CsgF protein DUF155 PF02582.9 EIM91256.1 - 1.2e-41 142.5 0.0 1.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LRR_4 PF12799.2 EIM91257.1 - 0.00046 19.7 0.0 0.25 11.0 0.0 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM91257.1 - 0.0046 16.6 2.7 19 5.0 0.0 4.2 3 1 1 4 4 4 3 Leucine rich repeat PRK PF00485.13 EIM91258.1 - 7.3e-50 169.2 0.0 1.1e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EIM91258.1 - 4.8e-44 150.0 0.0 7.7e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EIM91258.1 - 7.4e-06 26.7 0.0 1.7e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM91258.1 - 0.00042 20.6 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIM91258.1 - 0.001 18.9 0.0 0.0037 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM91258.1 - 0.034 13.2 0.0 0.083 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 EIM91258.1 - 0.33 10.3 4.7 0.22 10.9 0.8 2.4 2 1 0 2 2 2 0 Dephospho-CoA kinase APG17 PF04108.7 EIM91259.1 - 2.1e-26 92.6 19.5 2.3e-21 76.1 8.9 3.0 2 1 0 2 2 2 2 Autophagy protein Apg17 DUF3447 PF11929.3 EIM91259.1 - 0.013 15.2 0.3 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Arch_fla_DE PF04659.8 EIM91259.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.7 3 0 0 3 3 3 0 Archaeal flagella protein Syntaxin-6_N PF09177.6 EIM91259.1 - 0.27 11.6 6.4 6.1 7.3 0.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal AAA_35 PF14516.1 EIM91259.1 - 1.3 7.5 6.0 0.34 9.4 0.8 2.1 2 0 0 2 2 2 0 AAA-like domain FTO_CTD PF12934.2 EIM91259.1 - 1.6 8.2 6.3 0.9 9.0 0.2 2.7 2 1 1 3 3 3 0 FTO C-terminal domain UPF0184 PF03670.8 EIM91259.1 - 2 8.6 10.2 3.3 7.9 0.0 4.2 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0184) ADH_zinc_N PF00107.21 EIM91260.1 - 1.9e-13 50.0 0.0 3.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91260.1 - 3e-12 46.2 0.2 9.2e-12 44.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91260.1 - 0.0012 19.7 0.0 0.0056 17.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM91261.1 - 8.8e-13 47.9 0.0 1.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91261.1 - 1.8e-12 46.9 0.8 3e-12 46.2 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91261.1 - 0.0018 19.1 0.3 0.016 16.1 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase GPI-anchored PF10342.4 EIM91262.1 - 3.9e-09 36.8 0.9 3.9e-09 36.8 0.6 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GTPase_binding PF09027.5 EIM91262.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 GTPase binding PsbN PF02468.10 EIM91263.1 - 0.15 11.6 1.1 0.52 9.9 0.8 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF1600 PF07667.6 EIM91263.1 - 0.65 10.1 6.1 0.61 10.1 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Ceramidase PF05875.7 EIM91264.1 - 6.7e-76 254.8 12.0 7.8e-76 254.6 8.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF3421 PF11901.3 EIM91265.1 - 8.9e-13 48.0 0.1 3.2e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) Rot1 PF10681.4 EIM91266.1 - 2.5e-55 187.1 0.3 3e-55 186.8 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EIM91266.1 - 0.0082 16.7 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain WLM PF08325.5 EIM91267.1 - 2.6e-50 170.8 1.3 1.6e-49 168.3 0.0 2.5 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EIM91267.1 - 8.9e-06 25.6 0.1 1.5e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EIM91267.1 - 0.00074 18.5 0.4 0.0013 17.7 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.4 EIM91267.1 - 0.0019 17.8 0.3 0.0087 15.7 0.0 2.1 1 1 1 2 2 2 1 SprT-like family FdhE PF04216.7 EIM91267.1 - 0.53 9.9 1.9 5.4 6.6 0.6 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation PFK PF00365.15 EIM91268.1 - 1e-161 536.5 1.4 3.7e-95 318.1 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 EIM91268.1 - 0.2 11.5 0.0 0.6 10.0 0.0 1.7 1 0 0 1 1 1 0 FAM216B protein family Arylesterase PF01731.15 EIM91269.1 - 2.1e-06 27.6 0.1 0.047 13.6 0.0 2.6 2 0 0 2 2 2 2 Arylesterase Str_synth PF03088.11 EIM91269.1 - 0.0074 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.7 EIM91269.1 - 0.12 11.7 0.0 0.95 8.7 0.0 2.4 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region MFS_1 PF07690.11 EIM91270.1 - 1.9e-27 95.9 50.8 9.1e-25 87.1 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIM91270.1 - 0.08 12.9 8.0 0.3 11.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) PEN-2 PF10251.4 EIM91270.1 - 0.54 10.5 9.7 0.63 10.3 0.2 3.6 4 0 0 4 4 4 0 Presenilin enhancer-2 subunit of gamma secretase CaM_bdg_C0 PF10562.4 EIM91271.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Cep57_CLD_2 PF14197.1 EIM91273.1 - 0.014 15.3 9.4 0.014 15.3 6.5 5.7 5 2 2 7 7 7 0 Centrosome localisation domain of PPC89 Myosin_tail_1 PF01576.14 EIM91273.1 - 0.24 9.1 88.0 0.29 8.8 8.0 2.9 1 1 0 2 2 2 0 Myosin tail IncA PF04156.9 EIM91273.1 - 0.42 10.1 73.2 7.4 6.1 11.7 4.5 1 1 3 4 4 4 0 IncA protein Filament PF00038.16 EIM91273.1 - 4.6 6.6 71.6 25 4.1 23.9 3.5 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.7 EIM91273.1 - 5 7.4 12.7 4 7.7 0.5 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Alpha-amylase PF00128.19 EIM91274.1 - 5.1e-32 111.5 2.0 1.3e-31 110.2 1.4 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EIM91274.1 - 2.7e-05 22.2 0.1 0.037 11.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 F-box-like PF12937.2 EIM91275.1 - 3.5e-07 29.8 1.2 9e-07 28.5 0.8 1.7 1 0 0 1 1 1 1 F-box-like Formyl_trans_N PF00551.14 EIM91276.1 - 3.5e-27 95.1 0.0 5.9e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EIM91276.1 - 3.8e-09 36.5 0.0 5.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Thioredoxin PF00085.15 EIM91277.1 - 2.7e-59 197.3 0.0 1.6e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EIM91277.1 - 1.1e-20 74.0 0.7 3e-20 72.6 0.5 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EIM91277.1 - 3.4e-20 72.3 0.5 8e-09 35.6 0.0 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EIM91277.1 - 3.4e-13 49.4 0.0 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EIM91277.1 - 2.1e-12 46.9 0.1 0.00024 21.1 0.0 4.4 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EIM91277.1 - 2.3e-09 37.3 0.0 0.032 14.0 0.0 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 EIM91277.1 - 7.6e-07 28.8 0.1 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EIM91277.1 - 1e-05 25.1 0.3 0.056 12.9 0.0 2.4 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.19 EIM91277.1 - 0.0002 21.2 0.5 0.018 15.0 0.1 3.2 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.1 EIM91277.1 - 0.0005 19.6 0.9 1 8.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 EIM91277.1 - 0.00074 19.5 2.4 0.9 9.5 0.0 3.2 2 1 0 3 3 3 2 Thioredoxin TraF PF13728.1 EIM91277.1 - 0.0088 15.5 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein DSBA PF01323.15 EIM91277.1 - 0.014 14.9 4.2 23 4.4 0.1 4.7 3 2 2 5 5 5 0 DSBA-like thioredoxin domain GTSE1_N PF15259.1 EIM91277.1 - 0.051 13.5 0.5 0.11 12.4 0.2 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 DUF4141 PF13605.1 EIM91278.1 - 0.036 13.2 0.4 0.036 13.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) DDHD PF02862.12 EIM91279.1 - 6.8 6.4 9.4 9.2 5.9 6.5 1.2 1 0 0 1 1 1 0 DDHD domain MFS_1 PF07690.11 EIM91280.1 - 7.8e-34 116.9 36.3 7.8e-34 116.9 25.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 EIM91281.1 - 5.4e-130 433.6 13.5 6.4e-130 433.3 9.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Mad3_BUB1_I PF08311.7 EIM91282.1 - 2e-26 92.2 0.0 3.6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EIM91282.1 - 1.8e-16 60.0 0.0 2.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91282.1 - 1.8e-06 27.2 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EIM91282.1 - 5.1e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Sigma70_ner PF04546.8 EIM91282.1 - 0.007 16.0 0.3 0.007 16.0 0.2 2.5 2 0 0 2 2 2 1 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EIM91282.1 - 0.012 15.8 1.0 0.012 15.8 0.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Kinase-like PF14531.1 EIM91282.1 - 0.27 10.1 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TLP-20 PF06088.6 EIM91282.1 - 2.4 7.8 4.8 22 4.6 0.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.7 EIM91282.1 - 3.1 5.5 8.4 1.8 6.3 0.4 2.1 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 EIM91282.1 - 3.8 7.0 18.1 0.02 14.4 1.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4246 PF14033.1 EIM91283.1 - 1.5e-128 429.5 0.8 4.1e-128 428.1 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) MIP PF00230.15 EIM91284.1 - 2.4e-28 99.1 10.3 3.9e-28 98.4 7.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein LsmAD PF06741.8 EIM91286.1 - 1.1e-23 83.1 2.2 2.2e-23 82.0 1.6 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EIM91286.1 - 1.2e-05 25.1 0.1 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EIM91286.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Scd6-like Sm domain Epimerase PF01370.16 EIM91287.1 - 1.4e-21 77.0 0.2 3e-21 75.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIM91287.1 - 4.3e-10 38.9 0.4 2.1e-08 33.3 0.7 2.6 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EIM91287.1 - 2.4e-09 36.3 0.1 5e-09 35.2 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM91287.1 - 9.6e-09 35.4 1.3 3.1e-08 33.8 0.9 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIM91287.1 - 1.3e-05 24.5 0.2 2.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EIM91287.1 - 0.00023 20.1 0.0 0.004 16.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIM91287.1 - 0.0017 18.2 0.6 0.0017 18.2 0.4 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Arylesterase PF01731.15 EIM91288.1 - 3.8e-05 23.5 0.6 0.002 18.0 0.4 2.7 1 1 0 1 1 1 1 Arylesterase SGL PF08450.7 EIM91288.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region BRO1 PF03097.13 EIM91289.1 - 8.2e-85 284.8 0.1 1.7e-84 283.7 0.1 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIM91289.1 - 4.9e-67 225.9 5.8 4.9e-67 225.9 4.0 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cluap1 PF10234.4 EIM91289.1 - 4.3 6.4 8.8 9.1 5.3 1.9 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 RasGAP PF00616.14 EIM91291.1 - 3.5e-54 183.4 0.0 3.5e-54 183.4 0.0 2.5 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIM91291.1 - 3e-36 124.2 0.5 3e-36 124.2 0.4 2.3 2 0 0 2 2 2 1 RasGAP C-terminus KxDL PF10241.4 EIM91291.1 - 0.033 14.0 2.9 0.43 10.5 0.2 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF972 PF06156.8 EIM91291.1 - 0.15 12.4 3.6 16 5.9 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Glyco_transf_20 PF00982.16 EIM91292.1 - 2.5e-180 600.0 0.0 6e-140 466.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EIM91292.1 - 0.0035 16.7 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 MIF4G PF02854.14 EIM91293.1 - 2.3e-56 190.5 0.4 3.2e-56 190.0 0.3 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EIM91293.1 - 9.4e-17 60.6 0.0 2.2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EIM91293.1 - 0.0057 16.3 0.0 0.039 13.6 0.0 2.2 2 0 0 2 2 2 1 MA3 domain DUF445 PF04286.7 EIM91293.1 - 0.056 12.9 5.5 0.39 10.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) HD PF01966.17 EIM91295.1 - 0.00016 21.6 1.6 0.001 19.0 0.1 2.6 2 1 0 2 2 2 1 HD domain Zip PF02535.17 EIM91296.1 - 8.5e-53 179.3 18.6 9.8e-47 159.4 7.5 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter NUDIX PF00293.23 EIM91297.1 - 8.8e-13 48.0 0.3 1.2e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Rep_fac_C PF08542.6 EIM91298.1 - 8.3e-21 73.7 0.1 4.2e-20 71.5 0.0 2.2 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIM91298.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIM91298.1 - 7.9e-06 26.1 0.2 2.3e-05 24.6 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIM91298.1 - 0.0017 17.4 0.6 1.2 8.1 0.2 2.7 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIM91298.1 - 0.0024 18.0 1.6 0.035 14.2 0.7 2.9 1 1 2 3 3 3 1 AAA domain AAA_10 PF12846.2 EIM91298.1 - 0.0025 17.2 0.6 0.044 13.2 0.0 2.4 2 1 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EIM91298.1 - 0.0032 17.4 0.7 0.21 11.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain SNF2_N PF00176.18 EIM91298.1 - 0.0073 15.1 0.2 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_33 PF13671.1 EIM91298.1 - 0.0096 15.8 0.3 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EIM91298.1 - 0.012 15.6 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_pol3_delta PF06144.8 EIM91298.1 - 0.012 15.1 0.1 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TSC21 PF15217.1 EIM91298.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 TSC21 family Mg_chelatase PF01078.16 EIM91298.1 - 0.071 12.2 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Lipoprotein_18 PF06804.6 EIM91298.1 - 0.11 11.2 0.5 0.16 10.6 0.4 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein AAA_5 PF07728.9 EIM91298.1 - 0.12 12.0 0.4 0.29 10.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2795 PF11387.3 EIM91300.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) DUF2370 PF10176.4 EIM91301.1 - 2e-48 164.8 0.0 4e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM51 PF15345.1 EIM91301.1 - 9.4e-05 22.2 0.1 0.00021 21.0 0.1 1.6 1 1 0 1 1 1 1 Transmembrane protein 51 Methyltransf_23 PF13489.1 EIM91302.1 - 0.00014 21.5 0.0 0.00043 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FAM101 PF15068.1 EIM91302.1 - 0.83 9.0 6.8 0.23 10.8 1.2 2.2 2 0 0 2 2 2 0 FAM101 family ATP_synt_H PF05493.8 EIM91303.1 - 2.9e-20 72.0 7.0 3.4e-20 71.8 4.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EIM91303.1 - 0.031 13.6 3.8 0.032 13.6 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_M50B PF13398.1 EIM91303.1 - 0.069 12.5 1.7 0.072 12.4 1.2 1.1 1 0 0 1 1 1 0 Peptidase M50B-like ARL6IP6 PF15062.1 EIM91303.1 - 0.071 13.0 0.2 0.097 12.5 0.1 1.4 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix DUF3353 PF11833.3 EIM91303.1 - 0.15 11.4 0.8 0.16 11.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Exosortase_EpsH PF09721.5 EIM91303.1 - 0.22 10.7 5.6 0.22 10.7 3.9 1.0 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) Claudin_2 PF13903.1 EIM91303.1 - 0.34 10.5 2.7 0.36 10.5 1.8 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MgtE PF01769.11 EIM91303.1 - 0.43 10.8 2.5 0.48 10.7 1.8 1.0 1 0 0 1 1 1 0 Divalent cation transporter UPF0197 PF05251.7 EIM91303.1 - 0.86 9.9 6.0 2.8 8.2 4.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Fig1 PF12351.3 EIM91303.1 - 3 7.7 5.6 3.1 7.6 3.9 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4234 PF14018.1 EIM91303.1 - 5.6 6.7 5.5 1e+02 2.7 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) MIF4G PF02854.14 EIM91304.1 - 1.9e-30 105.8 0.0 2.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain zf-C3HC PF07967.8 EIM91305.1 - 7e-22 77.6 0.0 2e-20 72.9 0.0 2.9 4 0 0 4 4 4 1 C3HC zinc finger-like Rsm1 PF08600.5 EIM91305.1 - 6.8e-14 51.4 0.6 0.0007 19.4 0.0 4.2 4 0 0 4 4 4 3 Rsm1-like DM PF00751.13 EIM91305.1 - 0.13 11.7 0.3 7 6.2 0.0 2.4 2 0 0 2 2 2 0 DM DNA binding domain MIF4G PF02854.14 EIM91308.1 - 4.6e-28 98.0 0.0 6e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain YniB PF14002.1 EIM91308.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 YniB-like protein Glyco_hydro_1 PF00232.13 EIM91310.1 - 2.6e-107 358.8 0.9 3.4e-107 358.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Casein_kappa PF00997.13 EIM91310.1 - 0.16 11.6 6.8 0.35 10.5 4.7 1.6 1 0 0 1 1 1 0 Kappa casein p450 PF00067.17 EIM91312.1 - 6.6e-71 239.2 0.0 8.7e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.14 EIM91313.1 - 6.8e-47 160.3 0.0 1.4e-46 159.3 0.0 1.5 1 0 0 1 1 1 1 RNB domain zf-C2H2_2 PF12756.2 EIM91314.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Aldo_ket_red PF00248.16 EIM91315.1 - 4.1e-51 173.4 0.0 4.7e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 EIM91316.1 - 1.8e-43 148.5 0.0 6.3e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91316.1 - 1.5e-19 70.1 0.0 5.4e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM91316.1 - 1.9e-06 27.0 0.0 0.0078 15.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIM91316.1 - 0.0024 17.6 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 EIM91317.1 - 1e-10 40.9 0.0 1.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91317.1 - 1.6e-07 31.0 11.2 2.8e-07 30.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps51 PF08700.6 EIM91319.1 - 1.8e-23 82.2 2.1 2.4e-23 81.7 1.4 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EIM91319.1 - 0.0007 19.5 4.4 0.0011 18.9 3.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EIM91319.1 - 0.001 17.6 2.4 0.0013 17.2 1.7 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.7 EIM91319.1 - 0.026 14.7 2.5 0.038 14.2 1.8 1.2 1 0 0 1 1 1 0 FlgN protein Metallophos PF00149.23 EIM91323.1 - 3.7e-08 32.9 1.3 9e-08 31.7 0.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM91323.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EIM91323.1 - 0.0084 14.2 0.0 0.013 13.5 0.0 1.2 1 0 0 1 1 1 1 Firmicute fructose-1,6-bisphosphatase PRMT5 PF05185.11 EIM91324.1 - 3.5e-157 523.9 0.0 4.4e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase ABM PF03992.11 EIM91324.1 - 0.013 15.4 0.5 0.037 14.0 0.4 1.7 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Met_10 PF02475.11 EIM91324.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PAT1 PF09770.4 EIM91324.1 - 4.4 5.4 11.4 6.9 4.7 7.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank_4 PF13637.1 EIM91325.1 - 0.0021 18.5 0.0 0.31 11.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FlxA PF14282.1 EIM91325.1 - 0.029 14.2 15.3 0.86 9.5 0.3 3.7 2 1 1 3 3 3 0 FlxA-like protein Laminin_II PF06009.7 EIM91325.1 - 0.11 12.2 8.2 2.6 7.8 1.2 3.1 2 1 0 2 2 2 0 Laminin Domain II DUF1795 PF08786.6 EIM91325.1 - 0.25 11.1 4.2 0.26 11.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) MMPL PF03176.10 EIM91325.1 - 0.28 9.8 1.3 0.54 8.9 0.9 1.4 1 0 0 1 1 1 0 MMPL family DUF4391 PF14335.1 EIM91325.1 - 2.3 7.5 10.2 0.11 11.8 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4391) FlaC_arch PF05377.6 EIM91325.1 - 2.5 8.0 7.4 8.5 6.3 0.2 4.0 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Viral_P18 PF04521.8 EIM91325.1 - 4.6 6.7 7.3 1 8.8 0.5 2.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_MLP1_2 PF07926.7 EIM91325.1 - 4.8 6.9 28.2 0.51 10.0 5.4 3.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CorA PF01544.13 EIM91325.1 - 6.5 5.6 8.8 4.3 6.2 2.5 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GATA PF00320.22 EIM91326.1 - 5.1e-14 51.3 3.5 1.1e-13 50.2 2.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EIM91326.1 - 6.5e-05 22.8 0.0 0.0002 21.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EIM91326.1 - 0.00026 20.9 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIM91326.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold LRR_4 PF12799.2 EIM91327.1 - 2.9e-48 160.7 60.7 5.5e-10 38.6 1.7 7.6 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM91327.1 - 2.6e-30 103.9 57.5 1.1e-09 37.8 0.8 6.3 3 2 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 EIM91327.1 - 4.8e-18 65.3 12.7 3.4e-08 33.2 0.9 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EIM91327.1 - 2.5e-17 60.2 32.9 0.7 10.1 0.2 12.1 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 EIM91327.1 - 8.3e-14 50.0 27.8 0.42 10.8 0.0 11.0 7 3 4 11 11 11 5 Leucine Rich repeat LRR_7 PF13504.1 EIM91327.1 - 2.6e-09 35.7 29.3 3.1 8.3 0.1 11.3 11 2 1 12 12 12 3 Leucine rich repeat LRR_3 PF07725.7 EIM91327.1 - 8.9 6.2 11.4 1.1e+02 2.8 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4078 PF13300.1 EIM91328.1 - 1.9e-18 66.3 4.2 1.9e-18 66.3 2.9 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4078) RNase_H2-Ydr279 PF09468.5 EIM91328.1 - 0.22 10.6 5.0 1.3 8.1 3.3 2.1 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) MFS_1 PF07690.11 EIM91329.1 - 1.8e-24 86.1 27.2 1.8e-24 86.1 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EIM91330.1 - 1.1e-14 54.9 0.0 4e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM91330.1 - 6e-12 45.7 0.1 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.16 EIM91332.1 - 6.5e-21 74.8 1.4 4.8e-20 72.0 1.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM91332.1 - 3.6e-18 65.2 0.0 5.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM91332.1 - 8.2e-15 55.2 0.8 2.9e-14 53.4 0.6 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIM91332.1 - 2.1e-13 49.7 0.5 1.1e-12 47.4 0.3 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIM91332.1 - 6.9e-06 25.4 1.4 8.5e-06 25.1 0.2 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EIM91332.1 - 2.9e-05 23.1 0.2 0.19 10.5 0.1 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 EIM91332.1 - 0.0002 21.3 0.5 0.00077 19.4 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIM91332.1 - 0.0012 17.7 0.1 0.0038 16.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EIM91332.1 - 0.016 14.1 0.1 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Med26 PF08711.6 EIM91333.1 - 2e-09 36.8 0.0 5.3e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Imm2 PF14426.1 EIM91333.1 - 0.14 12.1 2.2 1 9.3 0.1 2.5 2 0 0 2 2 2 0 Immunity protein Imm2 HATPase_c PF02518.21 EIM91334.1 - 3.5e-41 139.3 0.0 1e-20 73.4 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIM91334.1 - 1.7e-35 121.4 0.4 9.8e-18 64.2 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIM91334.1 - 7.3e-20 70.7 3.0 8e-11 41.7 0.0 3.1 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EIM91334.1 - 9.7e-07 28.5 0.0 0.0021 17.7 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 EIM91334.1 - 7.9e-05 22.2 0.0 0.03 14.0 0.0 2.7 2 0 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.1 EIM91334.1 - 0.00059 19.6 0.0 0.069 12.9 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_8 PF13188.1 EIM91334.1 - 0.001 18.8 0.0 0.0041 16.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.1 EIM91334.1 - 0.0084 16.4 0.1 0.82 10.0 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EIM91334.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold GAF_3 PF13492.1 EIM91334.1 - 0.022 14.8 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 GAF domain PAS_4 PF08448.5 EIM91334.1 - 0.052 13.5 0.1 0.48 10.4 0.0 2.8 4 0 0 4 4 4 0 PAS fold IucA_IucC PF04183.7 EIM91335.1 - 2.8e-21 75.9 0.2 2.6e-20 72.7 0.2 2.1 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 EIM91335.1 - 1.5e-13 51.0 0.1 3.1e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.7 EIM91336.1 - 7.6e-20 71.2 0.0 2.5e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 EIM91336.1 - 9.8e-11 41.8 0.1 5.1e-10 39.5 0.1 2.0 1 1 0 1 1 1 1 Ferric iron reductase FhuF-like transporter DUF4646 PF15496.1 EIM91337.1 - 4.2e-07 30.0 0.7 8.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) CS PF04969.11 EIM91338.1 - 1.1e-08 35.4 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 CS domain Sel1 PF08238.7 EIM91338.1 - 0.092 13.4 0.1 5 7.8 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_2 PF07719.12 EIM91338.1 - 0.17 11.8 0.4 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cu-oxidase_3 PF07732.10 EIM91340.1 - 4.4e-46 155.4 2.8 4.7e-44 148.8 0.6 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM91340.1 - 1.8e-34 118.1 4.6 3.8e-30 104.1 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EIM91340.1 - 2.1e-28 99.2 1.7 1.6e-25 89.8 0.2 3.2 3 0 0 3 3 3 2 Multicopper oxidase C2 PF00168.25 EIM91341.1 - 2.3e-11 43.3 0.0 3.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Abhydrolase_5 PF12695.2 EIM91342.1 - 3.5e-10 39.7 0.0 4.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM91342.1 - 1.4e-09 38.2 0.1 2.3e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM91342.1 - 0.0009 18.8 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EIM91342.1 - 0.02 13.8 0.0 1.2 8.0 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1749) VirJ PF06057.6 EIM91342.1 - 0.036 13.8 0.0 0.071 12.8 0.0 1.4 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.3 EIM91342.1 - 0.082 12.7 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EIM91342.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) E1-E2_ATPase PF00122.15 EIM91343.1 - 3.1e-56 189.9 0.6 3.1e-56 189.9 0.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIM91343.1 - 2.8e-45 154.0 4.9 2.8e-45 154.0 3.4 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIM91343.1 - 1e-26 94.7 0.0 5.9e-26 92.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIM91343.1 - 4.9e-16 58.4 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIM91343.1 - 4.4e-14 53.0 0.0 1.3e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIM91343.1 - 3.7e-10 39.1 0.1 1.2e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIM91343.1 - 1.7e-05 24.5 0.4 0.0031 17.1 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EIM91345.1 - 4.3e-38 130.9 18.5 4.3e-38 130.9 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91345.1 - 4.9e-14 51.7 5.8 4.9e-14 51.7 4.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIM91345.1 - 0.0023 16.2 3.3 0.0023 16.2 2.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Myosin_tail_1 PF01576.14 EIM91349.1 - 0.0013 16.5 5.1 0.0019 16.0 3.5 1.1 1 0 0 1 1 1 1 Myosin tail UPF0242 PF06785.6 EIM91349.1 - 0.0041 15.8 3.7 0.0066 15.1 2.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 EIM91349.1 - 0.013 15.3 7.7 0.032 14.0 5.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EIM91349.1 - 0.021 14.4 11.8 0.04 13.5 8.2 1.5 1 0 0 1 1 1 0 IncA protein Herpes_U30 PF04523.8 EIM91349.1 - 0.027 11.9 3.0 0.046 11.1 2.1 1.3 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Flagellin_N PF00669.15 EIM91349.1 - 0.054 13.2 7.5 0.2 11.4 5.1 2.0 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Seryl_tRNA_N PF02403.17 EIM91349.1 - 0.06 13.3 3.9 0.86 9.6 0.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cob_adeno_trans PF01923.13 EIM91349.1 - 0.069 12.9 3.1 0.13 12.0 2.0 1.6 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Mnd1 PF03962.10 EIM91349.1 - 0.082 12.5 3.8 0.15 11.7 2.6 1.4 1 0 0 1 1 1 0 Mnd1 family CDC37_N PF03234.9 EIM91349.1 - 0.096 13.0 2.8 0.18 12.1 2.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding FlxA PF14282.1 EIM91349.1 - 0.11 12.4 12.0 0.11 12.4 7.2 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 EIM91349.1 - 0.14 12.4 1.9 0.42 10.9 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EIM91349.1 - 0.21 11.8 4.5 0.61 10.3 0.3 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EIM91349.1 - 1.4 8.0 8.7 3 6.9 6.0 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CorA PF01544.13 EIM91349.1 - 1.5 7.7 4.8 2.8 6.9 3.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TBPIP PF07106.8 EIM91349.1 - 2.5 7.6 8.3 10 5.6 3.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EIM91349.1 - 3.2 5.4 3.9 4.4 5.0 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EIM91349.1 - 4.3 7.1 8.6 52 3.6 6.0 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Oxidored_molyb PF00174.14 EIM91350.1 - 1.3e-49 167.8 0.0 2e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIM91350.1 - 5.4e-11 42.2 0.0 7.1e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain CBM_5_12 PF02839.9 EIM91351.1 - 3.6e-10 39.2 10.9 3.6e-10 39.2 7.6 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain F-box-like PF12937.2 EIM91352.1 - 0.0038 16.9 0.0 0.014 15.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like Maf1 PF09174.5 EIM91353.1 - 1.8e-36 125.6 0.1 1e-29 103.6 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator DAO PF01266.19 EIM91354.1 - 4.3e-48 164.0 0.0 5.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM91354.1 - 3.2e-07 30.6 0.0 0.00084 19.4 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM91354.1 - 5.1e-05 23.5 0.4 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM91354.1 - 5.2e-05 23.1 0.0 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM91354.1 - 0.0056 16.4 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIM91354.1 - 0.0057 15.5 0.3 0.025 13.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EIM91354.1 - 0.024 13.7 0.3 0.42 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 EIM91354.1 - 0.076 11.9 0.0 0.2 10.5 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EIM91354.1 - 0.11 10.9 0.0 0.69 8.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.16 EIM91355.1 - 2e-120 402.3 39.6 2.5e-120 402.0 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIM91355.1 - 7.7e-34 116.9 42.8 1e-33 116.5 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EIM91356.1 - 1.2e-31 109.7 17.6 1.2e-31 109.7 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91356.1 - 1.7e-12 46.6 5.6 1.7e-12 46.6 3.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIM91356.1 - 0.00025 19.3 3.5 0.00025 19.3 2.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EIM91357.1 - 2.9e-25 88.7 41.8 1.5e-21 76.5 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM91357.1 - 0.0021 16.3 3.6 0.029 12.5 1.7 2.4 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EIM91358.1 - 1.1e-07 30.8 13.0 0.00016 20.5 2.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_4 PF13613.1 EIM91358.1 - 0.027 14.0 0.1 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Serglycin PF04360.7 EIM91359.1 - 0.074 12.7 3.9 0.15 11.7 2.7 1.5 1 0 0 1 1 1 0 Serglycin Ctf8 PF09696.5 EIM91360.1 - 9.5e-21 73.8 0.2 4.6e-20 71.6 0.2 1.8 1 1 0 1 1 1 1 Ctf8 YTH PF04146.10 EIM91361.1 - 2.9e-44 150.0 0.0 4.7e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EIM91361.1 - 9.2e-06 25.2 0.0 0.014 15.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM91361.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM91361.1 - 0.012 15.5 0.0 0.053 13.5 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.20 EIM91362.1 - 6.6e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIM91362.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIM91362.1 - 0.081 12.4 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Mito_carr PF00153.22 EIM91363.1 - 3.3e-55 183.7 0.1 9.1e-21 73.3 0.1 4.3 4 1 0 4 4 4 4 Mitochondrial carrier protein YtxH PF12732.2 EIM91363.1 - 0.04 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 YtxH-like protein ATG22 PF11700.3 EIM91364.1 - 7.6e-119 397.3 30.1 8.6e-119 397.1 20.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF962 PF06127.6 EIM91364.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF962) Phytoreo_Pns PF05451.6 EIM91365.1 - 0.012 14.3 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Mitofilin PF09731.4 EIM91366.1 - 2.4e-109 366.6 18.2 2.9e-109 366.3 12.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein PspA_IM30 PF04012.7 EIM91367.1 - 0.027 13.8 5.5 0.049 12.9 3.8 1.4 1 0 0 1 1 1 0 PspA/IM30 family DivIC PF04977.10 EIM91367.1 - 0.078 12.4 3.5 0.17 11.3 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 EIM91367.1 - 0.14 12.2 2.2 0.29 11.2 1.6 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Viral_P18 PF04521.8 EIM91367.1 - 0.16 11.4 1.1 0.27 10.6 0.7 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein ABC_tran_2 PF12848.2 EIM91367.1 - 1.3 8.9 6.8 2.4 8.0 4.7 1.4 1 0 0 1 1 1 0 ABC transporter DOR PF14839.1 EIM91367.1 - 2.4 7.8 6.8 9 5.9 0.0 2.2 2 0 0 2 2 2 0 DOR family Nucleoporin_FG PF13634.1 EIM91368.1 - 1.1e-33 115.7 182.4 1.6e-15 57.2 42.5 4.9 1 1 3 4 4 4 4 Nucleoporin FG repeat region Coagulase PF08764.5 EIM91368.1 - 0.12 12.3 1.6 0.21 11.5 1.0 1.4 1 1 0 1 1 1 0 Staphylococcus aureus coagulase Trehalase PF01204.13 EIM91370.1 - 1.3e-163 545.3 0.0 1.6e-163 545.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EIM91370.1 - 9.2e-14 50.4 0.3 1.7e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cation_efflux PF01545.16 EIM91371.1 - 6.6e-31 107.4 4.0 7.9e-31 107.1 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family Claudin_2 PF13903.1 EIM91371.1 - 0.014 15.0 0.7 0.69 9.5 0.1 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Lipase_3 PF01764.20 EIM91372.1 - 3.4e-06 26.7 0.0 7.6e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIM91372.1 - 0.0091 15.7 0.0 0.038 13.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EIM91372.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EIM91372.1 - 0.13 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein MFS_1 PF07690.11 EIM91373.1 - 4.8e-32 111.0 38.5 8.3e-25 87.2 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91373.1 - 2.9e-22 78.8 9.7 6.6e-22 77.7 6.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_4 PF01565.18 EIM91376.1 - 4.1e-15 55.4 0.1 8.4e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM91376.1 - 5.3e-05 23.0 1.0 0.00011 21.9 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like GST_N_3 PF13417.1 EIM91378.1 - 2.5e-18 66.0 0.0 3.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM91378.1 - 8.1e-14 51.3 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIM91378.1 - 9.5e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM91378.1 - 3e-12 46.3 0.0 4.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM91378.1 - 2.2e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIM91378.1 - 0.00026 21.4 0.0 0.00033 21.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 EIM91380.1 - 3.1e-09 37.0 0.0 1.3e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIM91380.1 - 1.5e-05 24.5 0.0 0.052 13.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIM91380.1 - 2.1e-05 24.6 0.0 0.16 12.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM91380.1 - 0.00037 20.4 0.0 2.6 8.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EIM91380.1 - 0.0011 19.4 0.0 0.19 12.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PPR_2 PF13041.1 EIM91380.1 - 0.036 14.0 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 PPR repeat family ABC_membrane PF00664.18 EIM91382.1 - 4.1e-59 200.2 23.1 2.4e-32 112.4 6.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM91382.1 - 8.9e-49 165.3 0.0 6.9e-27 94.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM91382.1 - 8.7e-10 39.0 1.1 0.15 11.9 0.0 4.3 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 EIM91382.1 - 2.7e-08 33.3 4.0 0.021 14.0 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIM91382.1 - 7.5e-06 26.0 0.5 0.022 14.7 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain Miro PF08477.8 EIM91382.1 - 3.2e-05 24.4 0.3 0.17 12.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIM91382.1 - 3.5e-05 23.7 0.7 0.06 13.2 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EIM91382.1 - 4.7e-05 22.8 0.1 0.039 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM91382.1 - 0.0002 20.8 1.4 0.64 9.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIM91382.1 - 0.00076 19.0 0.2 0.059 12.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EIM91382.1 - 0.00096 19.5 0.7 0.33 11.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIM91382.1 - 0.0011 18.7 0.3 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM91382.1 - 0.0014 19.4 0.5 1.8 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM91382.1 - 0.0014 18.7 1.3 0.47 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EIM91382.1 - 0.0028 17.3 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EIM91382.1 - 0.0069 16.2 0.1 0.98 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EIM91382.1 - 0.007 15.9 0.4 0.033 13.8 0.0 2.3 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EIM91382.1 - 0.0078 15.8 0.2 2.9 7.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain ATP_bind_1 PF03029.12 EIM91382.1 - 0.008 15.7 0.5 5.9 6.3 0.0 3.5 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EIM91382.1 - 0.0081 15.6 0.5 2.4 7.4 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EIM91382.1 - 0.011 15.4 1.0 0.14 11.9 0.0 3.2 3 0 0 3 3 2 0 Part of AAA domain cobW PF02492.14 EIM91382.1 - 0.021 14.2 0.6 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EIM91382.1 - 0.022 15.0 0.3 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EIM91382.1 - 0.022 13.6 0.0 5 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EIM91382.1 - 0.024 14.4 1.7 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 EIM91382.1 - 0.027 13.0 0.6 3.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_13 PF13166.1 EIM91382.1 - 0.03 12.8 0.0 0.048 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIM91382.1 - 0.032 13.9 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 1 0 Archaeal ATPase DUF258 PF03193.11 EIM91382.1 - 0.036 13.2 1.4 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EIM91382.1 - 0.037 13.5 0.6 5 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EIM91382.1 - 0.039 13.0 0.4 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 EIM91382.1 - 0.16 11.4 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4349 PF14257.1 EIM91382.1 - 0.23 10.6 1.8 0.46 9.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF87 PF01935.12 EIM91382.1 - 3.5 7.3 6.0 1 9.1 0.4 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 MULE PF10551.4 EIM91383.1 - 1.5e-06 28.2 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EIM91383.1 - 0.00013 21.3 0.6 0.00032 20.1 0.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-H2C2_5 PF13909.1 EIM91384.1 - 7.9 6.9 8.2 2.4 8.5 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain UPF0061 PF02696.9 EIM91385.1 - 1.7e-89 300.3 0.0 2.4e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Voldacs PF03517.8 EIM91386.1 - 1.3e-26 93.0 0.0 2.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Glyco_trans_1_3 PF13528.1 EIM91391.1 - 1.5e-08 34.1 0.0 5.1e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 1 PTPlike_phytase PF14566.1 EIM91392.1 - 2.9e-117 387.6 0.0 2.9e-39 134.5 0.0 3.7 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIM91392.1 - 3.3e-05 23.3 0.0 0.032 13.5 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 EIM91392.1 - 0.00043 20.1 0.0 6.9 6.6 0.0 3.8 3 0 0 3 3 3 2 C-terminal general transcription factor TFIIE alpha DSPc PF00782.15 EIM91392.1 - 0.002 17.6 0.0 0.22 11.1 0.0 3.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIM91392.1 - 0.0046 17.2 0.0 3 8.0 0.0 3.7 4 0 0 4 4 4 1 Tyrosine phosphatase family GMP_synt_C PF00958.17 EIM91393.1 - 2.7e-41 139.1 0.1 5.6e-41 138.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EIM91393.1 - 1.4e-35 122.4 0.0 2.5e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EIM91393.1 - 2.1e-10 39.9 0.1 2.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EIM91393.1 - 2.2e-08 33.8 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EIM91393.1 - 0.00076 18.8 0.0 0.0024 17.1 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EIM91393.1 - 0.0026 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EIM91393.1 - 0.0033 16.0 0.1 0.006 15.1 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EIM91393.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 EIM91393.1 - 0.054 12.9 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.14 EIM91393.1 - 0.095 11.7 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase DUF2392 PF10288.4 EIM91393.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Lon_C PF05362.8 EIM91394.1 - 6e-70 234.7 0.1 9.6e-70 234.0 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIM91394.1 - 1.2e-35 123.1 1.2 1.7e-35 122.6 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIM91394.1 - 2.2e-21 76.4 0.0 8.1e-21 74.6 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIM91394.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EIM91394.1 - 4.7e-07 29.3 0.0 1.1e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EIM91394.1 - 4.7e-06 26.6 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIM91394.1 - 6.6e-05 22.9 0.1 0.00055 19.9 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EIM91394.1 - 6.9e-05 23.6 0.0 0.0003 21.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EIM91394.1 - 0.00017 20.4 0.0 0.00031 19.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 EIM91394.1 - 0.00069 19.7 0.0 0.0091 16.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIM91394.1 - 0.00071 18.6 1.2 0.0017 17.4 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EIM91394.1 - 0.0013 19.0 2.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIM91394.1 - 0.0015 18.4 0.0 0.0054 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIM91394.1 - 0.006 15.3 0.2 0.078 11.6 0.1 2.5 3 0 0 3 3 3 1 TIP49 C-terminus RNA_helicase PF00910.17 EIM91394.1 - 0.011 15.9 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase SKI PF01202.17 EIM91394.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_25 PF13481.1 EIM91394.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIM91394.1 - 0.029 14.0 0.1 0.15 11.7 0.0 2.2 2 1 1 3 3 2 0 NTPase UPF0079 PF02367.12 EIM91394.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EIM91394.1 - 0.06 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EIM91394.1 - 0.069 12.8 1.5 3.1 7.4 0.0 3.1 2 2 1 3 3 3 0 Archaeal ATPase DUF258 PF03193.11 EIM91394.1 - 0.087 12.0 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_3 PF07726.6 EIM91394.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EIM91394.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 EIM91396.1 - 1.6e-26 92.6 0.0 8.8e-26 90.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EIM91396.1 - 0.0043 15.6 0.0 0.007 14.9 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter MFS_1 PF07690.11 EIM91397.1 - 5.1e-35 120.8 51.8 1.8e-33 115.7 35.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91397.1 - 3.5e-16 58.8 12.2 3.5e-16 58.8 8.5 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EIM91397.1 - 2.8e-14 52.2 25.7 4.4e-14 51.6 17.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_halogenase PF04820.9 EIM91398.1 - 2e-33 115.7 0.0 1.5e-19 69.9 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EIM91398.1 - 1.9e-12 46.8 0.3 4.3e-11 42.4 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM91398.1 - 3.9e-09 35.8 0.0 0.00021 20.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIM91398.1 - 2.4e-06 26.9 0.0 1e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91398.1 - 5.5e-06 26.3 0.0 2.3e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIM91398.1 - 1.1e-05 25.6 0.1 0.019 15.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM91398.1 - 1.6e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM91398.1 - 0.00013 20.5 0.0 0.0039 15.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EIM91398.1 - 0.0021 17.2 0.0 0.0069 15.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EIM91398.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM91398.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIM91398.1 - 0.024 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EIM91398.1 - 0.036 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIM91398.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EIM91398.1 - 0.092 12.7 0.1 3.3 7.6 0.0 2.5 3 0 0 3 3 3 0 NADH(P)-binding ApbA PF02558.11 EIM91398.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EIM91398.1 - 0.11 12.4 0.2 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain MFS_1 PF07690.11 EIM91399.1 - 1.9e-33 115.6 25.5 5.5e-33 114.1 18.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily EutH PF04346.7 EIM91399.1 - 0.00098 18.1 0.1 0.0021 17.0 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH DUF3169 PF11368.3 EIM91399.1 - 0.033 13.3 0.0 0.094 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Flu_M1 PF00598.14 EIM91399.1 - 0.097 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) MFS_1_like PF12832.2 EIM91399.1 - 0.17 11.6 2.8 0.2 11.4 0.1 2.7 3 0 0 3 3 3 0 MFS_1 like family DUF1049 PF06305.6 EIM91399.1 - 3.5 7.1 6.9 0.64 9.5 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1049) Methyltransf_11 PF08241.7 EIM91400.1 - 5e-10 39.7 0.0 1.2e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91400.1 - 7.7e-08 32.0 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM91400.1 - 1.9e-07 30.4 0.0 5.8e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIM91400.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91400.1 - 2.9e-06 27.0 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91400.1 - 2.7e-05 24.5 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIM91400.1 - 0.046 13.3 0.0 0.11 12.0 0.0 1.7 1 1 0 2 2 2 0 Hypothetical methyltransferase TPMT PF05724.6 EIM91400.1 - 0.052 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MFS_1 PF07690.11 EIM91401.1 - 1.6e-33 115.9 26.1 3.1e-33 114.9 17.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 EIM91401.1 - 0.0024 17.1 0.6 0.0098 15.1 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3169) CBM_5_12 PF02839.9 EIM91403.1 - 5.4e-12 45.1 12.3 5.4e-12 45.1 8.5 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EIM91403.1 - 0.013 15.0 3.0 0.013 15.0 2.1 2.4 3 0 0 3 3 3 0 Cellulose-binding domain DUF4157 PF13699.1 EIM91403.1 - 0.043 13.9 0.5 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Terpene_synth_C PF03936.11 EIM91403.1 - 0.088 12.0 0.1 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Fork_head PF00250.13 EIM91404.1 - 1.2e-07 31.6 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Fork head domain TauD PF02668.11 EIM91406.1 - 6.5e-56 189.8 0.2 8e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.22 EIM91407.1 - 8.3e-15 53.8 3.6 1.7e-14 52.8 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Erg28 PF03694.8 EIM91409.1 - 6.1e-36 122.8 3.1 7.9e-36 122.4 2.2 1.1 1 0 0 1 1 1 1 Erg28 like protein NACHT PF05729.7 EIM91411.1 - 3.1e-10 39.9 0.0 8.7e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain XendoU PF09412.5 EIM91411.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU APS_kinase PF01583.15 EIM91411.1 - 0.13 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.27 EIM91412.1 - 1.3e-56 186.5 32.3 1.7e-12 46.6 0.4 9.9 10 0 0 10 10 10 6 WD domain, G-beta repeat PD40 PF07676.7 EIM91412.1 - 1.5e-09 37.2 6.5 0.048 13.3 0.2 7.6 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIM91412.1 - 4.8e-09 36.1 0.0 0.15 11.7 0.0 4.6 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIM91412.1 - 9.2e-06 24.0 2.9 0.5 8.4 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 EIM91412.1 - 1.7e-05 23.6 0.1 1.2 7.6 0.0 4.3 3 2 1 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 EIM91412.1 - 0.00014 21.1 1.7 0.25 10.4 0.0 4.3 4 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIM91412.1 - 0.00015 20.6 9.3 0.14 10.9 0.3 4.8 2 2 0 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 EIM91412.1 - 0.00083 18.8 0.0 0.64 9.4 0.0 2.9 2 1 0 2 2 2 2 PQQ-like domain Hira PF07569.6 EIM91412.1 - 0.047 12.8 0.0 11 5.1 0.0 4.0 4 1 1 5 5 5 0 TUP1-like enhancer of split Na_Ca_ex PF01699.19 EIM91413.1 - 7.2e-37 126.1 31.3 2.4e-20 72.5 8.0 2.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein ADH_zinc_N PF00107.21 EIM91414.1 - 2.8e-19 68.9 0.0 4.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM91414.1 - 4.1e-19 69.7 0.0 9.4e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91414.1 - 2.3e-13 49.8 0.1 7.8e-13 48.1 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EIM91415.1 - 1.9e-64 216.6 16.6 2.3e-33 115.4 2.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EIM91415.1 - 8.8e-30 102.6 0.0 1.8e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EIM91415.1 - 1.3e-28 99.8 10.7 1.8e-15 57.0 1.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 EIM91415.1 - 3.6e-11 42.9 0.0 3.9e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 EIM91415.1 - 0.0097 15.5 11.3 0.089 12.4 1.3 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIM91415.1 - 0.022 13.8 0.3 2.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 EIM91415.1 - 0.024 14.9 5.7 0.8 10.0 0.0 2.8 3 0 0 3 3 3 0 C-terminal domain on CstA (DUF4161) Phage_portal_2 PF05136.8 EIM91415.1 - 0.026 13.0 0.0 2.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage portal protein, lambda family DUF543 PF04418.7 EIM91415.1 - 5.3 7.0 9.5 5.4 7.0 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) PAS_3 PF08447.6 EIM91416.1 - 6.8e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIM91416.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIM91416.1 - 0.00017 21.9 0.0 0.00044 20.5 0.0 1.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 EIM91416.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 PAS domain Ank_2 PF12796.2 EIM91417.1 - 1.5e-48 163.0 7.4 1.1e-19 70.4 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIM91417.1 - 1.1e-28 97.5 19.3 7.7e-05 22.3 0.1 8.7 8 2 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 EIM91417.1 - 1.9e-25 86.3 5.0 0.0011 19.0 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EIM91417.1 - 3.3e-23 81.6 6.9 3.4e-07 30.6 0.1 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM91417.1 - 6.9e-15 54.7 10.9 4e-06 26.8 0.2 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) NIL PF09383.5 EIM91417.1 - 0.036 13.6 0.3 0.13 11.8 0.2 2.0 1 0 0 1 1 1 0 NIL domain KRTAP7 PF15034.1 EIM91417.1 - 1.9 9.1 4.2 4.2 8.0 0.4 2.5 2 1 1 3 3 3 0 KRTAP type 7 family DUF1748 PF08520.5 EIM91418.1 - 5.1e-27 93.3 0.0 5.6e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Rad51 PF08423.6 EIM91419.1 - 6.3e-14 51.4 0.0 1.7e-12 46.8 0.0 2.3 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIM91419.1 - 3.6e-08 33.0 0.2 1.2e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EIM91419.1 - 2.9e-05 23.2 0.2 4.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EIM91419.1 - 0.00094 18.3 0.3 0.0035 16.5 0.2 2.0 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EIM91419.1 - 0.0015 18.7 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIM91419.1 - 0.0049 16.8 0.2 0.0097 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 EIM91419.1 - 0.012 14.9 0.5 0.035 13.5 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PAXNEB PF05625.6 EIM91419.1 - 0.016 14.1 0.8 0.81 8.4 0.0 2.6 3 0 0 3 3 3 0 PAXNEB protein DUF2075 PF09848.4 EIM91419.1 - 0.016 14.1 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EIM91419.1 - 0.02 14.6 0.3 0.055 13.2 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EIM91419.1 - 0.039 13.5 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EIM91419.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM91419.1 - 0.085 12.5 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EIM91419.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EIM91419.1 - 0.16 11.4 0.3 5.8 6.3 0.1 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Med22 PF06179.7 EIM91420.1 - 2.1e-15 56.6 3.1 3.3e-15 56.0 2.2 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3006 PF11213.3 EIM91420.1 - 0.089 12.5 1.5 0.33 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) SCP2 PF02036.12 EIM91421.1 - 2.5e-24 85.4 1.2 3.1e-24 85.1 0.9 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIM91421.1 - 1.2e-05 25.3 0.9 1.5e-05 24.9 0.6 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal CelD_N PF02927.9 EIM91421.1 - 0.18 12.1 0.9 0.52 10.6 0.6 2.0 1 1 0 1 1 1 0 N-terminal ig-like domain of cellulase Dynamin_N PF00350.18 EIM91422.1 - 3.3e-41 140.9 0.0 7.3e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIM91422.1 - 6.4e-09 35.0 0.0 1.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EIM91422.1 - 0.0016 18.4 0.0 0.0053 16.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIM91422.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EIM91422.1 - 0.063 13.2 0.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIM91422.1 - 0.27 11.5 2.6 20 5.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain DAO PF01266.19 EIM91423.1 - 5.6e-20 71.5 2.6 3.3e-19 69.0 1.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91423.1 - 2.5e-05 24.2 0.1 6.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIM91423.1 - 0.00012 22.2 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EIM91423.1 - 0.0002 20.5 0.1 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIM91423.1 - 0.00021 21.5 0.1 0.00053 20.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM91423.1 - 0.0073 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM91423.1 - 0.014 14.2 0.2 0.02 13.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EIM91423.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIM91423.1 - 0.048 12.5 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EIM91423.1 - 0.073 11.5 0.2 0.18 10.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EIM91423.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIM91423.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHDPS PF00701.17 EIM91424.1 - 1e-30 106.3 0.0 6.6e-30 103.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Serinc PF03348.10 EIM91425.1 - 1.1e-154 515.2 12.3 1.3e-154 515.0 8.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 EIM91425.1 - 0.4 10.7 6.8 0.23 11.5 1.2 2.5 2 0 0 2 2 2 0 Vaculolar membrane protein Glyco_hydro_81 PF03639.8 EIM91426.1 - 1.4e-90 304.3 15.4 1.9e-90 303.8 10.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Fascin PF06268.8 EIM91426.1 - 4e-05 23.6 0.0 0.04 14.0 0.0 2.5 1 1 1 2 2 2 2 Fascin domain Vps39_1 PF10366.4 EIM91427.1 - 1.6e-29 102.0 0.2 7.9e-29 99.8 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EIM91427.1 - 1.2e-23 83.3 0.1 3.2e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EIM91427.1 - 5.6e-21 75.1 0.0 1.4e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EIM91427.1 - 9.8e-12 44.6 2.6 1e-06 28.3 0.3 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS Ank_2 PF12796.2 EIM91428.1 - 5.6e-25 87.5 4.8 1.5e-11 44.4 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM91428.1 - 8.6e-24 83.0 8.2 1e-07 31.9 0.1 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EIM91428.1 - 2.1e-22 77.7 2.9 5.4e-07 29.1 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EIM91428.1 - 1.7e-19 69.7 5.2 7e-07 29.5 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM91428.1 - 6.1e-19 66.2 0.2 0.001 19.0 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat AAA_27 PF13514.1 EIM91428.1 - 0.62 7.6 7.9 1.1 6.8 0.9 2.1 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 EIM91429.1 - 8.3e-68 228.7 28.0 2.2e-34 119.1 4.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM91429.1 - 1.8e-50 170.8 0.0 7.1e-29 100.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM91429.1 - 1.6e-08 34.8 0.6 0.00026 21.0 0.3 4.0 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.14 EIM91429.1 - 2.1e-07 30.4 2.7 0.0055 15.9 0.0 3.5 3 1 1 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIM91429.1 - 2.4e-05 23.8 0.1 0.04 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM91429.1 - 0.00012 21.5 1.8 0.081 12.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIM91429.1 - 0.00021 21.7 0.4 0.35 11.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 EIM91429.1 - 0.00025 20.6 0.5 0.32 10.4 0.1 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 EIM91429.1 - 0.0003 21.2 3.6 0.2 12.1 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EIM91429.1 - 0.0003 20.8 0.2 0.22 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIM91429.1 - 0.00037 21.3 2.3 0.8 10.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EIM91429.1 - 0.00051 19.9 3.2 0.087 12.7 0.2 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM91429.1 - 0.0028 16.8 0.8 1.3 8.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIM91429.1 - 0.0078 15.6 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EIM91429.1 - 0.0079 15.8 2.6 0.12 12.0 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIM91429.1 - 0.0088 15.1 0.4 1.8 7.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EIM91429.1 - 0.01 15.9 4.0 6.4 6.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EIM91429.1 - 0.012 14.2 2.6 0.23 10.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EIM91429.1 - 0.017 14.6 0.5 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EIM91429.1 - 0.018 14.8 3.2 0.47 10.2 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EIM91429.1 - 0.019 15.2 1.5 5.8 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EIM91429.1 - 0.033 13.8 0.3 0.033 13.8 0.2 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EIM91429.1 - 0.04 13.5 2.0 0.09 12.4 0.2 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EIM91429.1 - 0.058 12.9 4.8 6.5 6.2 0.3 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EIM91429.1 - 0.069 12.0 1.2 6.6 5.5 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.1 EIM91429.1 - 0.092 11.1 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIM91429.1 - 0.095 12.2 3.8 6.2 6.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 EIM91429.1 - 0.12 11.2 1.5 3.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.12 EIM91429.1 - 0.2 11.4 6.1 0.33 10.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EIM91429.1 - 0.31 10.4 3.6 0.35 10.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIM91429.1 - 0.33 10.8 4.3 8.2 6.2 0.2 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EIM91429.1 - 0.41 10.1 1.8 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.24 EIM91430.1 - 4.5e-38 130.4 0.0 1.9e-36 125.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM91430.1 - 6.9e-18 64.2 0.1 2.1e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM91430.1 - 4.1e-11 43.0 0.4 3.6e-10 39.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIM91430.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EIM91430.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 EIM91430.1 - 0.56 10.3 5.8 3.6 7.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain DUF605 PF04652.11 EIM91430.1 - 1.7 7.9 16.0 3.1 7.0 11.1 1.3 1 0 0 1 1 1 0 Vta1 like Piwi PF02171.12 EIM91431.1 - 8.3e-84 281.1 0.0 1.1e-83 280.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIM91431.1 - 1.8e-17 62.4 0.1 4.4e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIM91431.1 - 1.1e-07 31.2 0.0 2.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain THF_DHG_CYH PF00763.18 EIM91431.1 - 0.18 11.8 0.1 9.7 6.2 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Asp PF00026.18 EIM91432.1 - 1.9e-22 79.9 0.8 8.7e-21 74.4 0.6 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIM91432.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIM91432.1 - 0.011 16.2 0.1 0.15 12.5 0.1 2.8 3 0 0 3 3 3 0 Aspartyl protease IncA PF04156.9 EIM91432.1 - 0.098 12.2 0.7 0.26 10.8 0.5 1.6 1 0 0 1 1 1 0 IncA protein p450 PF00067.17 EIM91435.1 - 5.6e-64 216.3 0.0 4.8e-63 213.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM91436.1 - 7.3e-58 196.2 0.0 1.1e-56 192.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.15 EIM91437.1 - 1.8e-18 67.1 0.0 3.3e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.27 EIM91438.1 - 2.7e-26 90.4 6.0 3.4e-07 29.8 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIM91438.1 - 0.0028 15.8 0.2 0.073 11.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF3_subunit PF08597.5 EIM91439.1 - 5.7e-50 170.1 11.9 6.4e-50 169.9 8.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Asp PF00026.18 EIM91440.1 - 6.4e-24 84.7 1.7 9.5e-23 80.9 1.2 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIM91440.1 - 6e-05 23.4 0.2 0.0048 17.3 0.1 2.6 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EIM91440.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RVP PF00077.15 EIM91440.1 - 0.13 12.1 0.1 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Glyco_hydro_11 PF00457.12 EIM91441.1 - 1.3e-76 256.0 19.7 1.6e-76 255.7 13.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EIM91441.1 - 1.7e-10 40.3 10.8 6e-10 38.6 7.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EIM91441.1 - 0.74 9.9 8.9 1.8 8.6 6.2 1.7 1 1 0 1 1 1 0 Toxin 7 STAT_alpha PF01017.15 EIM91442.1 - 0.0037 16.9 0.8 0.0066 16.1 0.5 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain FliJ PF02050.11 EIM91442.1 - 0.012 15.6 3.3 0.76 9.8 0.0 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein IncA PF04156.9 EIM91442.1 - 1.5 8.3 6.7 0.57 9.7 0.5 2.3 1 1 0 2 2 2 0 IncA protein Spc7 PF08317.6 EIM91442.1 - 6.6 5.2 6.5 4.5 5.8 2.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3340 PF11818.3 EIM91444.1 - 4.1 7.3 11.9 0.28 11.1 4.4 1.9 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) F-box-like PF12937.2 EIM91445.1 - 1.5e-05 24.6 0.4 4.2e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91445.1 - 0.73 9.5 5.3 8.8 6.1 1.0 2.9 2 0 0 2 2 2 0 F-box domain BRICHOS PF04089.9 EIM91446.1 - 0.045 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain TAP_C PF03943.8 EIM91448.1 - 1.1e-06 27.9 0.0 3.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EIM91448.1 - 0.001 18.6 2.5 0.0018 17.8 1.0 1.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EIM91448.1 - 0.007 15.9 0.2 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat UBA_4 PF14555.1 EIM91448.1 - 0.036 13.5 0.1 0.092 12.2 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain NTF2 PF02136.15 EIM91448.1 - 0.13 12.6 0.1 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DUF4231 PF14015.1 EIM91449.1 - 0.66 9.9 4.2 1.3 9.0 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Prenyltrans_1 PF13243.1 EIM91450.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_2 PF13249.1 EIM91450.1 - 0.012 15.9 0.0 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase-like COesterase PF00135.23 EIM91451.1 - 6.1e-90 302.4 0.0 1.6e-88 297.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM91451.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EIM91452.1 - 1.1e-97 327.9 0.0 1.4e-97 327.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM91452.1 - 0.00035 20.1 0.0 0.00077 19.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIM91452.1 - 0.19 10.9 0.3 0.29 10.3 0.2 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.17 EIM91454.1 - 2.5e-45 155.3 0.0 5e-45 154.3 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.23 EIM91455.1 - 9.7e-94 314.9 0.0 1.2e-93 314.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIM91455.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DIOX_N PF14226.1 EIM91456.1 - 5.1e-10 39.9 0.0 1.7e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM91456.1 - 0.002 18.3 0.0 0.01 16.1 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM91457.1 - 4.7e-15 56.1 0.1 2.3e-14 53.9 0.0 2.2 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIM91457.1 - 1.8e-14 53.8 0.0 8.6e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SPA PF08616.5 EIM91458.1 - 4.4e-05 23.1 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 EIM91458.1 - 0.00024 20.8 3.6 0.0037 16.9 0.4 3.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Frag1 PF10277.4 EIM91459.1 - 3.3e-40 137.8 8.5 4e-40 137.6 5.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family ETRAMP PF09716.5 EIM91459.1 - 0.093 12.6 0.3 0.26 11.2 0.2 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF998 PF06197.8 EIM91459.1 - 0.1 11.9 14.2 0.11 11.7 8.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) PEN-2 PF10251.4 EIM91459.1 - 0.95 9.7 7.6 0.64 10.2 0.2 2.5 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2157 PF09925.4 EIM91459.1 - 1.5 8.4 6.9 0.2 11.2 1.5 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Bax1-I PF01027.15 EIM91459.1 - 1.7 8.2 19.3 1.2e+02 2.1 13.3 3.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4064 PF13273.1 EIM91459.1 - 3.3 7.8 13.4 2.7 8.1 5.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 EIM91459.1 - 7.7 5.8 7.1 18 4.7 3.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_hydro_43 PF04616.9 EIM91460.1 - 5.7e-17 61.7 4.7 9.2e-17 61.0 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 dCMP_cyt_deam_1 PF00383.17 EIM91461.1 - 7e-13 48.1 0.2 1.5e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_10 PF00331.15 EIM91462.1 - 2.1e-89 299.7 0.0 2.5e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EIM91462.1 - 2.7e-13 49.3 14.5 8.7e-13 47.6 10.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase PF00150.13 EIM91462.1 - 0.038 13.1 0.1 0.095 11.8 0.0 1.6 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.22 EIM91464.1 - 1.7e-36 125.1 0.0 2.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EIM91464.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Phe_ZIP PF08916.6 EIM91464.1 - 0.14 12.4 0.0 17 5.7 0.0 2.8 3 0 0 3 3 3 0 Phenylalanine zipper Glyco_hydro_17 PF00332.13 EIM91465.1 - 2e-11 43.5 3.2 2.1e-09 36.8 0.7 2.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3446 PF11928.3 EIM91465.1 - 0.0034 17.5 1.7 0.012 15.8 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) RhoGAP PF00620.22 EIM91466.1 - 3.4e-09 36.4 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DEAD PF00270.24 EIM91469.1 - 3.1e-34 117.8 0.7 3.4e-33 114.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM91469.1 - 1.5e-25 88.8 0.1 3.4e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIM91469.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_22 PF13401.1 EIM91469.1 - 0.033 14.3 0.4 0.3 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF1811 PF08838.5 EIM91469.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) AAA_30 PF13604.1 EIM91469.1 - 0.072 12.6 0.1 0.24 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain ketoacyl-synt PF00109.21 EIM91472.1 - 3.9e-74 249.3 0.2 3.7e-59 200.2 0.0 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIM91472.1 - 9.3e-47 159.8 0.0 2.2e-42 145.5 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EIM91472.1 - 7.8e-35 119.2 0.1 1.9e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EIM91472.1 - 9.2e-17 61.1 0.0 1.9e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EIM91472.1 - 5.6e-16 58.5 2.9 5.5e-08 32.9 0.3 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 EIM91472.1 - 5.7e-10 39.8 0.0 2.8e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EIM91472.1 - 3.7e-09 36.8 0.1 8.6e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM91472.1 - 2e-08 34.0 0.0 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EIM91472.1 - 0.0039 16.2 0.5 0.009 15.0 0.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PGAP1 PF07819.8 EIM91472.1 - 0.03 13.9 0.2 0.61 9.6 0.0 2.4 2 0 0 2 2 2 0 PGAP1-like protein Glyco_hydro_10 PF00331.15 EIM91473.1 - 9.7e-92 307.3 0.0 1.1e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EIM91473.1 - 6.8e-12 44.8 12.1 2e-11 43.3 8.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase PF00150.13 EIM91473.1 - 0.057 12.6 0.1 0.17 11.0 0.0 1.8 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) COQ9 PF08511.6 EIM91476.1 - 2.2e-09 36.7 0.0 3.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 COQ9 PRP4 PF08799.6 EIM91476.1 - 0.14 11.4 0.2 0.35 10.1 0.1 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GFA PF04828.9 EIM91477.1 - 3.7e-20 71.6 0.3 4.7e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EIM91477.1 - 0.073 12.7 0.0 0.073 12.7 0.0 2.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.7 EIM91477.1 - 0.077 12.7 0.0 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 EIM91477.1 - 0.17 11.4 3.1 0.48 9.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIM91477.1 - 0.19 11.0 3.6 0.22 10.8 0.0 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EIM91477.1 - 2 7.9 8.0 0.24 10.9 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EIM91477.1 - 6.6 6.5 8.8 0.56 9.9 0.2 2.8 3 0 0 3 3 3 0 Nudix N-terminal Peptidase_M20 PF01546.23 EIM91478.1 - 3e-21 75.7 0.0 4.2e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIM91478.1 - 5.2e-15 55.1 0.0 9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain LRR_8 PF13855.1 EIM91479.1 - 0.014 15.1 0.3 0.79 9.5 0.0 2.8 1 1 1 2 2 2 0 Leucine rich repeat Kelch_4 PF13418.1 EIM91481.1 - 1.4e-26 91.9 14.6 4.3e-08 32.7 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EIM91481.1 - 1.6e-20 72.6 26.2 2.1e-06 27.7 0.0 7.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EIM91481.1 - 3.7e-16 58.6 15.3 0.00028 20.7 0.0 6.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EIM91481.1 - 9.9e-16 56.8 6.4 4.4e-05 23.0 0.0 6.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EIM91481.1 - 6.5e-15 54.5 11.6 6e-05 23.0 0.0 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EIM91481.1 - 3e-11 42.6 0.7 0.049 13.1 0.0 5.9 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.5 EIM91481.1 - 0.031 13.5 0.4 0.079 12.2 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyoxal_oxid_N PF07250.6 EIM91481.1 - 0.043 12.8 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Tannase PF07519.6 EIM91482.1 - 2.3e-91 306.8 1.2 3.2e-91 306.4 0.8 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase APH PF01636.18 EIM91484.1 - 1.1e-11 44.9 0.1 1.4e-11 44.6 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIM91484.1 - 0.053 12.6 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 EIM91485.1 - 9.5e-14 51.6 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIM91485.1 - 0.069 12.2 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 EIM91485.1 - 0.088 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Fungal_trans_2 PF11951.3 EIM91489.1 - 7.3e-35 120.2 0.0 4e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91489.1 - 0.00065 19.5 9.3 0.0011 18.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.24 EIM91490.1 - 1.2e-33 115.4 1.8 1.9e-19 69.7 0.1 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EIM91490.1 - 8.4e-16 58.2 12.3 6.4e-09 36.0 2.4 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EIM91490.1 - 2.3e-08 33.9 1.9 5.7e-06 26.3 0.2 2.7 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 EIM91490.1 - 0.014 15.5 0.6 2.4 8.3 0.3 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EIM91490.1 - 0.02 14.8 5.8 0.078 12.8 0.0 2.7 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 EIM91490.1 - 0.07 12.6 0.3 1.3 8.5 0.0 2.8 2 1 1 3 3 3 0 Pleckstrin homology domain ACBP PF00887.14 EIM91491.1 - 5.1e-33 112.6 0.5 6.2e-33 112.3 0.4 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein DUF202 PF02656.10 EIM91492.1 - 1.9e-09 37.5 1.1 1.5e-08 34.7 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bac_rhodopsin PF01036.13 EIM91492.1 - 0.00048 19.5 1.1 0.0006 19.1 0.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PEX11 PF05648.9 EIM91493.1 - 4.4e-10 39.2 0.3 6.2e-07 28.9 0.0 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) LEAP-2 PF07359.6 EIM91494.1 - 1 9.0 8.2 1.6 8.4 0.3 3.3 3 1 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Colipase-like PF15083.1 EIM91494.1 - 1.2 9.1 16.4 2.6 8.0 3.2 3.8 1 1 1 2 2 2 0 Colipase-like Toxin_2 PF00451.14 EIM91494.1 - 2.4 8.3 27.8 0.62 10.2 2.1 5.5 3 2 1 4 4 4 0 Scorpion short toxin, BmKK2 DEAD PF00270.24 EIM91495.1 - 1.2e-11 44.4 0.1 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM91495.1 - 2.1e-07 30.9 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIM91495.1 - 0.071 12.3 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Mannitol_dh_C PF08125.8 EIM91496.1 - 1.6e-19 70.0 0.0 1.9e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Helicase_C PF00271.26 EIM91497.1 - 1.9e-10 40.4 0.1 3.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.3 EIM91499.1 - 1.4e-36 125.9 0.4 2.1e-36 125.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91499.1 - 1.4e-05 24.8 8.6 2.3e-05 24.2 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.8 EIM91500.1 - 3.4e-13 49.3 0.2 3.2e-09 36.4 0.0 2.5 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain zf-C2H2 PF00096.21 EIM91502.1 - 1.6e-12 46.9 15.1 0.00052 20.2 0.1 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM91502.1 - 9e-10 38.3 18.9 4.8e-05 23.4 0.2 3.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIM91502.1 - 3.2e-09 36.4 13.1 0.016 15.4 0.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIM91502.1 - 0.0036 17.1 6.8 0.063 13.2 0.2 3.2 3 1 1 4 4 4 2 C2H2-type zinc finger IBR PF01485.16 EIM91502.1 - 0.21 11.5 7.2 0.15 11.9 2.7 2.0 1 1 1 2 2 2 0 IBR domain Ogr_Delta PF04606.7 EIM91502.1 - 0.22 11.2 4.6 0.3 10.7 0.0 2.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 EIM91502.1 - 0.37 10.7 9.1 5.5 7.0 1.1 3.2 1 1 3 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EIM91502.1 - 0.75 9.6 10.6 0.34 10.7 1.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-met PF12874.2 EIM91502.1 - 1.5 9.1 10.4 4.1 7.7 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DnaJ PF00226.26 EIM91504.1 - 1.8e-27 94.8 1.9 2.5e-27 94.3 1.3 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIM91504.1 - 2e-20 72.4 1.4 3.2e-18 65.3 0.3 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DUF802 PF05650.6 EIM91505.1 - 0.051 13.6 0.2 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Acyl_transf_1 PF00698.16 EIM91508.1 - 4.8e-62 210.1 0.0 9.2e-61 205.9 0.0 2.6 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EIM91508.1 - 2.5e-30 104.3 0.0 8.7e-30 102.6 0.0 2.0 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EIM91508.1 - 2.6e-28 97.5 0.7 2.6e-28 97.5 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 EIM91508.1 - 3.6e-25 88.8 0.1 7.7e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EIM91508.1 - 1.1e-20 74.5 0.0 2.3e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EIM91508.1 - 1.2e-15 57.3 0.1 3.2e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 EIM91508.1 - 5.4e-14 51.9 0.0 1.5e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.1 EIM91508.1 - 1.9e-12 47.1 0.2 1.9e-10 40.6 0.1 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.20 EIM91508.1 - 8.4e-07 29.0 0.1 0.0019 18.1 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase DUF3597 PF12200.3 EIM91508.1 - 3.5 8.0 6.3 0.94 9.8 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) CTP_transf_2 PF01467.21 EIM91509.1 - 0.052 13.5 0.0 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 Cytidylyltransferase Sugar_tr PF00083.19 EIM91510.1 - 1.2e-108 363.6 26.4 1.3e-108 363.4 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM91510.1 - 1.8e-28 99.2 67.8 2.2e-26 92.4 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIM91510.1 - 0.017 13.3 5.5 0.0077 14.4 1.3 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Patatin PF01734.17 EIM91511.1 - 7e-26 91.4 0.1 1.1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase VSP PF03302.8 EIM91512.1 - 0.00039 19.1 20.1 0.00056 18.6 13.9 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4117 PF13491.1 EIM91512.1 - 0.04 13.3 0.8 0.13 11.7 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) Tim54 PF11711.3 EIM91512.1 - 1.7 7.1 10.1 2.6 6.5 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDK5_activator PF03261.10 EIM91512.1 - 2.1 7.5 13.3 3.4 6.8 9.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 EIM91512.1 - 5.2 6.8 30.8 7.9 6.2 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VTC PF09359.5 EIM91513.1 - 5.8e-98 327.3 0.5 1.6e-97 325.9 0.0 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EIM91513.1 - 4.5e-26 92.2 10.7 4.5e-26 92.2 7.4 3.6 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 EIM91513.1 - 3.9e-09 36.5 1.4 9.2e-09 35.3 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Gtr1_RagA PF04670.7 EIM91514.1 - 8.9e-48 162.4 0.0 1.3e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIM91514.1 - 0.0003 21.2 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM91514.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIM91514.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 EIM91514.1 - 0.047 13.0 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_14 PF13173.1 EIM91514.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIM91514.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EIM91514.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 EIM91514.1 - 0.16 10.5 0.0 0.32 9.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 EIM91514.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LRR_6 PF13516.1 EIM91515.1 - 5.7e-13 47.4 7.8 0.54 10.4 0.0 8.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 EIM91515.1 - 8.5e-12 44.4 8.9 0.036 13.7 0.0 5.9 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIM91515.1 - 1.4e-06 27.5 6.1 1.1 9.7 0.0 6.9 7 0 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.28 EIM91515.1 - 0.00069 19.3 17.3 7.3 7.0 0.0 7.5 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.1 EIM91515.1 - 0.032 13.9 14.7 1.5 8.6 0.1 5.8 4 3 0 4 4 4 0 Leucine rich repeat PrpF PF04303.8 EIM91516.1 - 1.3e-65 221.5 7.6 1.1e-28 100.0 1.1 4.5 3 1 0 3 3 3 3 PrpF protein CDC27 PF09507.5 EIM91518.1 - 5.3e-41 141.2 90.2 3.3e-29 102.3 23.4 3.2 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 XhlA PF10779.4 EIM91521.1 - 0.056 13.3 4.5 0.083 12.8 0.0 2.9 3 0 0 3 3 3 0 Haemolysin XhlA Transposase_21 PF02992.9 EIM91522.1 - 2.6e-06 26.6 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIM91522.1 - 1.8e-05 24.1 0.2 4.1e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ECH PF00378.15 EIM91526.1 - 3.4e-36 124.5 0.0 4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Cytochrom_B561 PF03188.11 EIM91527.1 - 6e-06 26.1 7.4 1.9e-05 24.4 5.2 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EIM91527.1 - 0.011 15.2 3.1 0.011 15.2 2.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) Ferric_reduct PF01794.14 EIM91527.1 - 0.58 10.2 14.8 1.6 8.8 4.7 2.8 1 1 2 3 3 3 0 Ferric reductase like transmembrane component FtsX PF02687.16 EIM91527.1 - 2.9 7.6 7.5 27 4.5 5.2 2.4 1 1 0 1 1 1 0 FtsX-like permease family Cyt-b5 PF00173.23 EIM91528.1 - 5.4e-19 67.7 0.0 7.3e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RAI1 PF08652.6 EIM91529.1 - 1.6e-19 69.4 0.1 4.3e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease DNA_pol_phi PF04931.8 EIM91531.1 - 3.7 5.1 8.0 5.4 4.6 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Plasmodium_Vir PF05795.6 EIM91532.1 - 0.12 11.5 2.4 0.18 10.9 1.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Whi5 PF08528.6 EIM91533.1 - 6.2e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Whi5 like TMEM171 PF15471.1 EIM91533.1 - 0.24 10.1 4.5 0.64 8.7 3.1 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Apt1 PF10351.4 EIM91533.1 - 5.6 5.7 10.0 13 4.5 7.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lysine_decarbox PF03641.9 EIM91535.1 - 1.8e-34 118.4 0.7 2.6e-34 117.9 0.5 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF1491 PF07372.7 EIM91535.1 - 0.14 12.1 0.6 2.4 8.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1491) Abhydrolase_3 PF07859.8 EIM91536.1 - 6.3e-17 61.8 0.0 8.7e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM91536.1 - 1.6e-11 43.5 0.0 1.6e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIM91536.1 - 7.9e-06 25.6 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIM91536.1 - 0.0074 15.7 0.1 0.25 10.7 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase p450 PF00067.17 EIM91537.1 - 4.1e-38 131.0 0.0 5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3025 PF11227.3 EIM91537.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Acyl-CoA_dh_M PF02770.14 EIM91538.1 - 0.0011 18.4 0.0 0.003 17.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain XPG_I PF00867.13 EIM91541.1 - 1e-17 63.9 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIM91541.1 - 5.1e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain Phage_integrase PF00589.17 EIM91542.1 - 1.3e-05 24.9 0.0 6.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Phage integrase family SAP PF02037.22 EIM91543.1 - 0.039 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 SAP domain MliC PF09864.4 EIM91545.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.5 1 1 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme adh_short PF00106.20 EIM91546.1 - 9.2e-22 77.7 0.3 1.3e-21 77.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM91546.1 - 7e-14 52.1 0.0 8.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EIM91546.1 - 1.4e-05 24.3 0.0 0.00016 20.8 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIM91546.1 - 0.00028 20.9 0.1 0.00052 20.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM91546.1 - 0.0091 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAE PF03283.8 EIM91546.1 - 0.12 10.9 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Meth_synt_2 PF01717.13 EIM91548.1 - 3.5e-21 75.5 0.0 2.1e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIM91548.1 - 1.6e-10 40.7 0.0 0.00048 19.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Oxidored_q2 PF00420.19 EIM91549.1 - 0.031 13.8 10.0 1 9.0 0.8 2.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cytomega_UL20A PF05984.7 EIM91549.1 - 0.19 11.9 0.2 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DUF2415 PF10313.4 EIM91550.1 - 8.2e-07 28.6 0.0 6.6e-06 25.6 0.0 2.5 4 0 0 4 4 4 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EIM91550.1 - 0.03 14.2 2.3 83 3.3 0.0 5.2 5 1 1 6 6 6 0 WD domain, G-beta repeat zf-CCCH PF00642.19 EIM91552.1 - 7.9e-06 25.4 11.3 5e-05 22.8 2.0 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIM91552.1 - 0.029 14.3 0.4 0.029 14.3 0.3 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Coq4 PF05019.8 EIM91553.1 - 6.4e-92 306.4 0.0 7.4e-92 306.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF3638 PF12340.3 EIM91555.1 - 1.6e-78 262.8 0.8 2.6e-78 262.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIM91555.1 - 3.4e-17 61.2 0.1 1.1e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) RRM_5 PF13893.1 EIM91556.1 - 8.6e-08 31.9 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM91556.1 - 2.3e-06 27.1 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM91556.1 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM91556.1 - 0.00086 19.0 0.1 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ADH_zinc_N PF00107.21 EIM91557.1 - 2.4e-11 43.3 0.0 3.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91557.1 - 1.4e-09 37.6 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91557.1 - 0.013 16.4 0.0 0.025 15.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIM91558.1 - 2e-12 46.7 0.0 3.6e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91558.1 - 7.7e-05 22.4 0.0 0.00023 20.8 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91558.1 - 0.0043 17.9 0.0 0.0086 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cpn10 PF00166.16 EIM91558.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit ADH_zinc_N PF00107.21 EIM91559.1 - 3.3e-13 49.3 0.0 5.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91559.1 - 3.3e-11 42.8 0.1 1e-10 41.3 0.1 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91559.1 - 0.015 16.2 0.0 0.036 14.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aminotran_1_2 PF00155.16 EIM91560.1 - 5.9e-26 91.2 0.0 7.3e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIM91560.1 - 7.7e-12 44.4 0.0 1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Ribosomal_L4 PF00573.17 EIM91561.1 - 6.1e-45 152.9 2.3 6.1e-45 152.9 1.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIM91561.1 - 8.2e-29 99.3 2.0 8.2e-29 99.3 1.4 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain ADH_zinc_N PF00107.21 EIM91562.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91562.1 - 2.9e-10 39.8 0.1 9.9e-10 38.1 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIM91562.1 - 0.0024 18.7 0.0 0.0058 17.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CbiG_N PF11760.3 EIM91562.1 - 0.031 13.9 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal DUF4066 PF13278.1 EIM91564.1 - 5.9e-15 54.9 0.3 2.8e-14 52.7 0.2 2.1 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EIM91564.1 - 3.9e-07 29.6 0.0 9.9e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family OPT PF03169.10 EIM91566.1 - 3.1e-153 511.5 45.5 3.5e-153 511.3 31.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ala_racemase_N PF01168.15 EIM91567.1 - 7.8e-41 140.0 0.0 9.4e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Hydrolase_like PF13242.1 EIM91567.1 - 0.1 12.3 0.1 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like SSF PF00474.12 EIM91568.1 - 6.8e-19 67.7 28.4 6.8e-19 67.7 19.7 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family CcmD PF04995.9 EIM91568.1 - 6.4 6.6 8.4 0.48 10.1 0.3 3.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Tmemb_14 PF03647.8 EIM91569.1 - 2.6e-24 85.4 6.7 2.9e-24 85.2 4.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EIM91569.1 - 0.0074 16.5 0.9 0.011 15.9 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DSPc PF00782.15 EIM91570.1 - 4.9e-27 94.1 0.0 3.6e-22 78.3 0.0 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIM91570.1 - 0.0059 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIM91570.1 - 0.18 11.8 0.4 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF4066 PF13278.1 EIM91571.1 - 3.9e-14 52.2 0.2 1.5e-12 47.1 0.2 2.6 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EIM91571.1 - 0.00034 20.0 0.0 0.00076 18.9 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_transf_22 PF03901.12 EIM91573.1 - 7.8e-14 51.4 8.3 1.1e-13 51.0 5.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3317 PF11779.3 EIM91573.1 - 4.1 6.9 7.9 1.9 7.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) ABC2_membrane PF01061.19 EIM91574.1 - 2.7e-35 121.4 18.2 2.7e-35 121.4 12.6 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EIM91574.1 - 1.1e-27 97.0 0.1 2.1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM91574.1 - 2.1e-09 37.7 0.1 6.7e-08 32.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EIM91574.1 - 6.7e-06 25.3 22.3 1.8e-05 23.9 15.5 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EIM91574.1 - 0.00067 19.1 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIM91574.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIM91574.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIM91574.1 - 0.0032 16.5 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EIM91574.1 - 0.0033 16.6 0.4 0.024 13.8 0.0 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.20 EIM91574.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 EIM91574.1 - 0.03 14.4 0.1 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM91574.1 - 0.058 13.3 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EIM91574.1 - 0.081 13.7 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIM91574.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIM91574.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EIM91574.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM91574.1 - 0.15 11.7 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EIM91574.1 - 0.2 11.9 0.1 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.8 EIM91574.1 - 1.1 9.4 30.9 0.023 14.8 6.6 3.9 3 0 0 3 3 2 0 EGF-like domain Glyco_transf_22 PF03901.12 EIM91575.1 - 3.3e-37 128.4 20.5 4.2e-37 128.1 14.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aldose_epim PF01263.15 EIM91577.1 - 8.5e-12 44.7 0.0 2.1e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Aldose 1-epimerase RNase_H PF00075.19 EIM91578.1 - 7.5e-22 78.0 0.0 2.9e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EIM91578.1 - 8.8e-17 60.8 0.9 1.9e-16 59.7 0.6 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-MYND PF01753.13 EIM91579.1 - 3.3e-11 42.8 8.1 7.6e-11 41.6 5.6 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIM91579.1 - 0.0082 15.9 4.4 0.029 14.2 3.1 2.0 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EIM91580.1 - 7.7e-12 44.8 4.6 1.9e-11 43.6 3.2 1.6 1 0 0 1 1 1 1 MYND finger DHquinase_I PF01487.10 EIM91580.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase Pkinase PF00069.20 EIM91581.1 - 8.4e-44 149.6 0.0 1.2e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91581.1 - 2e-23 82.8 0.0 1.3e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM91581.1 - 5e-05 22.4 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIM91581.1 - 0.00017 21.4 0.2 0.00086 19.0 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM91581.1 - 0.12 11.4 0.2 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn-ribbon_8 PF09723.5 EIM91582.1 - 9.5 6.2 8.3 14 5.7 0.5 2.2 1 1 1 2 2 2 0 Zinc ribbon domain UPF0014 PF03649.8 EIM91583.1 - 6.9e-43 146.6 14.3 8.6e-43 146.2 9.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Reticulon PF02453.12 EIM91583.1 - 1.4 8.4 6.6 1.7 8.1 1.1 2.8 2 1 1 3 3 3 0 Reticulon MIS13 PF08202.6 EIM91584.1 - 9.9e-21 74.0 4.4 2.4e-20 72.7 2.9 1.7 1 1 0 1 1 1 1 Mis12-Mtw1 protein family vMSA PF00695.14 EIM91584.1 - 0.021 14.0 0.5 0.036 13.2 0.3 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Cas_Cas1 PF01867.11 EIM91584.1 - 0.048 12.7 0.1 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Reo_sigmaC PF04582.7 EIM91585.1 - 0.068 12.3 9.0 0.0096 15.1 3.4 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EIM91585.1 - 1.7 8.4 38.8 0.41 10.4 3.6 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C2H2 PF00096.21 EIM91586.1 - 1.1e-12 47.5 14.6 0.00037 20.6 0.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM91586.1 - 6.4e-09 35.5 15.2 0.016 15.5 2.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM91586.1 - 5.9e-05 23.1 8.2 0.053 13.8 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM91586.1 - 0.003 17.4 4.3 2.8 7.9 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIM91586.1 - 0.021 14.9 3.3 24 5.2 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM91586.1 - 0.98 9.7 5.1 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2457 PF10446.4 EIM91586.1 - 3.2 6.3 23.2 4.2 6.0 5.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EIM91586.1 - 3.9 7.0 22.6 2.3 7.7 5.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region BTV_NS2 PF04514.7 EIM91586.1 - 9.5 4.9 8.1 2.2 7.0 0.4 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Gln-synt_C PF00120.19 EIM91587.1 - 1.5e-54 184.8 0.0 2.1e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Noggin PF05806.7 EIM91587.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Noggin Gln-synt_C PF00120.19 EIM91588.1 - 3.3e-52 177.2 0.0 4.3e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain 60KD_IMP PF02096.15 EIM91589.1 - 0.033 13.8 1.5 0.078 12.6 1.0 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein HMG_box PF00505.14 EIM91590.1 - 1.7e-06 28.1 5.0 3.9e-06 27.0 3.4 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.8 EIM91590.1 - 0.0044 17.2 1.5 0.0058 16.8 0.1 1.7 1 1 1 2 2 2 1 YABBY protein HMG_box_2 PF09011.5 EIM91590.1 - 0.0051 17.1 4.7 0.0084 16.4 3.2 1.5 1 1 0 1 1 1 1 HMG-box domain DUF1448 PF07289.6 EIM91590.1 - 0.11 11.4 0.3 0.13 11.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) EBV-NA3 PF05009.7 EIM91590.1 - 0.3 10.3 2.9 0.35 10.0 2.0 1.0 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_60s PF00428.14 EIM91590.1 - 2.7 8.4 15.8 2.5 8.5 10.2 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein PS_Dcarbxylase PF02666.10 EIM91592.1 - 1.2e-54 184.6 0.0 1.8e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EIM91592.1 - 1.3e-34 117.8 0.2 4.8e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EIM91592.1 - 0.001 19.1 0.1 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair CEP76-C2 PF15627.1 EIM91592.1 - 0.031 13.7 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 CEP76 C2 domain EF-hand_6 PF13405.1 EIM91592.1 - 0.042 13.7 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Shisa PF13908.1 EIM91593.1 - 0.52 10.4 2.4 0.75 9.9 0.0 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PRRSV_2b PF07069.6 EIM91593.1 - 0.99 9.7 6.8 0.21 11.8 0.2 2.7 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b DUF1183 PF06682.7 EIM91594.1 - 0.14 11.7 1.4 0.16 11.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_LMP2 PF07415.6 EIM91594.1 - 0.15 10.6 3.7 0.17 10.4 2.5 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein HpaP PF09483.5 EIM91594.1 - 0.16 11.9 1.7 0.17 11.7 1.2 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) CAF-1_p150 PF11600.3 EIM91594.1 - 0.22 10.8 4.1 0.25 10.7 2.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM101 PF15068.1 EIM91594.1 - 2.1 7.7 5.8 2.4 7.5 4.0 1.1 1 0 0 1 1 1 0 FAM101 family UPF0220 PF05255.6 EIM91597.1 - 0.13 11.5 6.4 0.18 11.0 0.6 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0220) zf-DHHC PF01529.15 EIM91600.1 - 0.083 12.2 1.3 0.1 11.9 0.3 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase FA_desaturase PF00487.19 EIM91600.1 - 0.13 11.6 2.7 5.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase TBPIP PF07106.8 EIM91602.1 - 8.5e-35 119.7 0.1 1e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EIM91602.1 - 0.0026 17.6 1.0 0.0026 17.6 0.7 2.4 2 0 0 2 2 2 1 bZIP transcription factor TrmB PF01978.14 EIM91602.1 - 0.011 15.4 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF972 PF06156.8 EIM91602.1 - 0.025 14.9 0.8 0.055 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EIM91602.1 - 0.11 12.8 6.4 0.067 13.4 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TMCO5 PF14992.1 EIM91602.1 - 0.14 11.2 1.5 0.22 10.6 1.1 1.2 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.9 EIM91602.1 - 0.25 10.9 2.7 0.4 10.2 1.9 1.4 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 EIM91603.1 - 2e-54 181.2 0.0 1.7e-20 72.5 0.0 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein GalKase_gal_bdg PF10509.4 EIM91604.1 - 3.1e-20 71.1 0.1 6e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EIM91604.1 - 1.2e-13 50.9 1.1 1.1e-12 47.8 0.8 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIM91604.1 - 6.6e-08 32.6 0.2 1.6e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Fungal_trans PF04082.13 EIM91605.1 - 1.2e-28 99.6 0.0 1.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91605.1 - 9.8e-11 41.3 9.6 1.9e-10 40.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIM91605.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Metallophos PF00149.23 EIM91606.1 - 5e-09 35.8 0.5 8.9e-09 35.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Beta_helix PF13229.1 EIM91607.1 - 3.2e-05 23.7 10.4 9.5e-05 22.1 7.0 1.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EIM91607.1 - 0.012 14.7 1.4 0.02 14.0 0.9 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Zn_clus PF00172.13 EIM91608.1 - 4.6e-06 26.4 11.0 9.1e-06 25.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YbgS PF13985.1 EIM91609.1 - 0.41 10.5 2.6 0.77 9.6 0.2 2.0 2 0 0 2 2 2 0 YbgS-like protein Metallophos PF00149.23 EIM91610.1 - 1.3e-10 41.0 0.7 5.7e-10 38.9 0.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPI_Ypi1 PF07491.6 EIM91611.1 - 2.8e-25 87.7 1.1 2.8e-25 87.7 0.7 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 EIM91611.1 - 0.083 11.2 5.9 0.1 10.9 4.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EIM91611.1 - 0.14 10.2 2.2 0.15 10.0 1.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Dehydrin PF00257.14 EIM91611.1 - 8.1 6.7 19.6 64 3.8 13.6 2.1 1 1 0 1 1 1 0 Dehydrin Glyco_hydro_18 PF00704.23 EIM91612.1 - 6.3e-14 52.1 7.8 6.8e-13 48.7 5.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.13 EIM91613.1 - 2.5e-11 43.2 9.4 6.3e-11 41.9 6.5 1.7 1 0 0 1 1 1 1 MYND finger IDO PF01231.13 EIM91614.1 - 1.4e-115 386.1 0.0 1.7e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Methyltransf_11 PF08241.7 EIM91615.1 - 8.2e-12 45.4 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91615.1 - 3.4e-09 36.6 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91615.1 - 4.2e-07 30.5 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91615.1 - 1.5e-06 28.2 0.0 3.9e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91615.1 - 4.7e-06 26.9 0.0 9.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91615.1 - 3e-05 24.2 0.0 6.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91615.1 - 0.0015 18.1 0.0 0.0057 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIM91615.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EIM91615.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EIM91615.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EIM91615.1 - 0.045 13.1 0.0 0.062 12.6 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EIM91615.1 - 0.097 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EIM91616.1 - 1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91616.1 - 4.9e-08 32.8 0.0 6.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91616.1 - 3e-06 27.7 0.0 5.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91616.1 - 5.4e-06 26.8 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91616.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91616.1 - 0.0023 18.2 0.0 0.0056 17.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91616.1 - 0.0074 15.8 0.0 0.039 13.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIM91616.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EIM91616.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EIM91616.1 - 0.11 11.8 0.0 0.29 10.4 0.0 1.6 1 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 EIM91617.1 - 1.9e-11 44.3 0.0 3.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91617.1 - 1.4e-07 32.0 0.0 2.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM91617.1 - 2.4e-07 30.6 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91617.1 - 3.9e-05 23.6 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91617.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91617.1 - 7.7e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91617.1 - 0.00012 22.3 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EIM91617.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FAD_binding_3 PF01494.14 EIM91618.1 - 2.1e-11 43.4 0.0 4.3e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM91618.1 - 0.05 13.6 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DDE_1 PF03184.14 EIM91619.1 - 5.4e-44 149.9 0.0 6.3e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF869 PF05911.6 EIM91620.1 - 0.001 17.4 8.2 0.0016 16.8 5.7 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EIM91620.1 - 0.0016 18.1 11.9 0.023 14.4 2.8 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIM91620.1 - 0.0028 16.7 13.8 0.0053 15.8 9.6 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 EIM91620.1 - 0.011 15.3 15.9 0.019 14.5 11.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF812 PF05667.6 EIM91620.1 - 0.024 13.1 10.0 0.053 12.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EIM91620.1 - 0.03 14.6 9.0 1.2 9.4 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EzrA PF06160.7 EIM91620.1 - 0.055 11.6 8.4 0.082 11.0 5.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EIM91620.1 - 0.1 11.7 3.7 0.16 11.0 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Peptidase_S46 PF10459.4 EIM91620.1 - 0.91 7.8 10.2 1.4 7.2 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 EIM91620.1 - 1.4 8.4 25.7 78 2.7 17.8 2.4 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 EIM91620.1 - 2 8.4 9.2 12 5.9 0.1 2.8 1 1 1 2 2 2 0 DivIVA protein TBPIP PF07106.8 EIM91620.1 - 2.1 7.8 10.1 4.4 6.8 1.0 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EIM91620.1 - 2.7 8.1 7.2 5.9 7.0 5.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PspB PF06667.7 EIM91620.1 - 6.1 6.8 5.7 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Mnd1 PF03962.10 EIM91620.1 - 6.7 6.3 15.2 1.5 8.4 6.9 2.1 1 1 1 2 2 2 0 Mnd1 family RVT_1 PF00078.22 EIM91622.1 - 8.4e-08 31.8 0.3 1.4e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIM91623.1 - 2.3e-07 30.3 3.8 4.6e-07 29.4 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIM91623.1 - 0.00044 20.2 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIM91623.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.1 EIM91623.1 - 0.05 13.3 0.3 0.19 11.4 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIM91623.1 - 0.058 13.0 0.3 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIM91623.1 - 0.059 12.8 2.7 0.13 11.7 1.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peptidase_A2B PF12384.3 EIM91623.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase ADH_N_assoc PF13823.1 EIM91623.1 - 0.17 11.5 0.8 0.5 10.0 0.5 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Cytochrom_C PF00034.16 EIM91626.1 - 2.2e-07 31.6 0.3 3.7e-07 30.8 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EIM91626.1 - 1e-06 28.7 3.6 1.4e-05 25.1 2.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EIM91626.1 - 0.0011 18.4 0.1 0.015 14.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain FAD_binding_3 PF01494.14 EIM91628.1 - 8.9e-15 54.5 0.0 5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EIM91628.1 - 0.00043 19.0 0.0 0.0012 17.5 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EIM91628.1 - 0.0088 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIM91628.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIM91628.1 - 0.14 10.9 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EIM91629.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIM91629.1 - 0.0051 15.4 0.1 0.0098 14.5 0.0 1.4 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 EIM91629.1 - 0.0068 15.5 1.0 0.046 12.7 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM91629.1 - 0.014 15.3 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIM91630.1 - 1.3e-13 50.7 3.4 1.7e-08 33.9 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EIM91630.1 - 2.4e-05 23.1 0.0 4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EIM91630.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIM91630.1 - 0.03 14.3 0.0 0.097 12.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIM91630.1 - 0.044 12.6 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.14 EIM91632.1 - 1.5e-10 40.6 1.5 7.4e-09 35.1 1.1 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIM91632.1 - 0.083 12.9 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EIM91633.1 - 1.6e-19 70.4 0.1 2.9e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM91633.1 - 2.7e-07 30.4 0.1 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EIM91633.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EIM91633.1 - 0.0024 17.8 0.1 0.0075 16.2 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM91633.1 - 0.0047 16.3 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EIM91633.1 - 0.016 14.8 0.1 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EIM91633.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 EIM91633.1 - 0.03 13.9 0.1 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.18 EIM91633.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_zinc_N PF00107.21 EIM91633.1 - 0.046 13.2 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Helicase_RecD PF05127.9 EIM91633.1 - 0.046 13.3 0.1 0.098 12.2 0.1 1.5 1 0 0 1 1 1 0 Helicase ApbA PF02558.11 EIM91633.1 - 0.073 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CcmD PF04995.9 EIM91633.1 - 0.67 9.7 2.7 6.2 6.6 0.3 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) FA_desaturase PF00487.19 EIM91634.1 - 1.4e-13 50.8 20.0 1.4e-13 50.8 13.8 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIM91634.1 - 5.7e-11 42.0 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aminotran_1_2 PF00155.16 EIM91635.1 - 1.2e-29 103.3 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIM91635.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Acetyltransf_7 PF13508.1 EIM91636.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM91636.1 - 0.00026 20.9 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EIM91636.1 - 0.015 15.1 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM91636.1 - 0.076 13.1 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EIM91637.1 - 9.4e-69 232.1 0.4 2e-68 231.0 0.3 1.4 1 1 0 1 1 1 1 Cytochrome P450 Defensin_big PF14862.1 EIM91638.1 - 0.1 12.6 0.6 0.36 10.9 0.4 2.0 1 1 0 1 1 1 0 Big defensin TFIIF_beta PF02270.10 EIM91639.1 - 3.3e-51 174.7 0.0 5.7e-51 173.9 0.0 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF3591 PF12157.3 EIM91639.1 - 0.0039 15.6 0.6 0.0056 15.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) BTB PF00651.26 EIM91640.1 - 4e-05 23.5 0.0 9.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SnoaL_2 PF12680.2 EIM91641.1 - 4.3e-07 30.2 0.4 8.6e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EIM91641.1 - 3.1e-06 26.7 0.1 6.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Glyco_hydro_61 PF03443.9 EIM91642.1 - 5.2e-78 261.8 0.0 5.2e-78 261.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 ABC_membrane PF00664.18 EIM91643.1 - 1.3e-37 129.7 8.9 1.6e-37 129.3 6.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIM91643.1 - 2e-34 118.8 0.0 5.2e-34 117.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EIM91643.1 - 4.3e-07 29.3 0.0 2.2e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM91643.1 - 7.3e-07 29.4 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM91643.1 - 0.0031 17.0 0.0 0.0075 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM91643.1 - 0.0037 17.4 0.1 0.059 13.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EIM91643.1 - 0.0054 16.6 0.7 0.057 13.3 0.5 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EIM91643.1 - 0.007 16.5 0.0 0.12 12.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIM91643.1 - 0.0089 16.0 0.1 0.034 14.1 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.1 EIM91643.1 - 0.039 13.8 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIM91643.1 - 0.046 14.5 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIM91643.1 - 0.054 12.8 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM91643.1 - 0.077 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 EIM91643.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EIM91643.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIM91643.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phosphoprotein PF00922.12 EIM91643.1 - 0.5 9.5 2.8 0.96 8.6 1.9 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein adh_short PF00106.20 EIM91644.1 - 4.2e-17 62.5 0.5 6.5e-17 61.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM91644.1 - 1.3e-06 28.4 0.0 2.2e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM91644.1 - 8.4e-06 25.3 0.2 3.9e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIM91644.1 - 0.00021 20.9 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Defensin_big PF14862.1 EIM91645.1 - 0.19 11.7 2.0 0.24 11.4 0.2 2.0 3 0 0 3 3 3 0 Big defensin ADH_zinc_N PF00107.21 EIM91646.1 - 3.8e-13 49.1 0.0 6.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM91646.1 - 2.5e-08 33.6 0.0 7.8e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIM91646.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EIM91646.1 - 0.078 13.8 0.0 0.31 11.9 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 EIM91646.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EIM91646.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Patatin PF01734.17 EIM91647.1 - 2.7e-27 96.0 0.0 4.2e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 EIM91648.1 - 6.4e-85 276.9 0.1 2.6e-11 43.0 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIM91648.1 - 9.1e-78 256.2 0.2 8.6e-15 54.4 0.0 6.6 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91648.1 - 3.6e-24 82.5 2.1 0.0092 15.7 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91648.1 - 4.3e-19 67.0 0.8 0.19 11.9 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91648.1 - 5.2e-13 48.0 4.6 2.6 7.7 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91648.1 - 9.4e-13 47.0 0.5 2 8.5 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91648.1 - 4.5e-09 36.7 0.0 0.065 13.9 0.0 4.6 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91648.1 - 8.5e-09 35.2 0.6 11 6.9 0.0 6.9 7 1 0 7 7 7 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EIM91648.1 - 3.2e-07 30.4 0.0 7.9 6.3 0.0 6.1 1 1 6 7 7 7 0 Rabaptin-like protein TPR_19 PF14559.1 EIM91648.1 - 6e-06 26.5 0.0 3.3 8.1 0.0 5.6 2 1 4 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM91648.1 - 0.00026 20.5 7.8 38 4.4 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIM91648.1 - 0.00026 21.1 0.0 22 5.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3268 PF11672.3 EIM91648.1 - 0.00066 19.7 0.1 1.1e+02 2.9 0.0 5.6 3 1 2 6 6 6 0 Protein of unknown function (DUF3268) DUF1697 PF08002.6 EIM91648.1 - 0.0027 17.7 0.4 6.4 6.8 0.0 4.3 1 1 4 5 5 5 1 Protein of unknown function (DUF1697) Spectrin PF00435.16 EIM91648.1 - 0.0085 16.3 0.5 1.9 8.8 0.0 3.1 3 0 0 3 3 3 1 Spectrin repeat DNA_gyraseB_C PF00986.16 EIM91648.1 - 0.014 15.0 0.1 39 4.0 0.0 5.2 6 0 0 6 6 6 0 DNA gyrase B subunit, carboxyl terminus TPR_5 PF12688.2 EIM91648.1 - 0.026 14.5 0.4 70 3.4 0.0 4.2 3 1 1 5 5 5 0 Tetratrico peptide repeat Peptidase_S28 PF05577.7 EIM91648.1 - 0.044 12.3 0.0 3.6 6.0 0.0 3.2 1 1 2 3 3 3 0 Serine carboxypeptidase S28 Vel1p PF10339.4 EIM91648.1 - 0.16 11.0 0.1 9.9 5.2 0.0 3.1 2 1 2 4 4 4 0 Yeast-specific zinc responsive Hemolysin_N PF12563.3 EIM91648.1 - 0.31 10.4 2.8 49 3.2 0.0 4.5 1 1 5 6 6 6 0 Hemolytic toxin N terminal Osmo_CC PF08946.5 EIM91648.1 - 0.41 10.6 2.6 41 4.3 0.0 4.4 6 0 0 6 6 5 0 Osmosensory transporter coiled coil LolA PF03548.10 EIM91650.1 - 0.08 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Pkinase PF00069.20 EIM91651.1 - 1.7e-14 53.5 0.0 1.8e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91651.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIM91652.1 - 0.07 12.2 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain ESX-1_EspG PF14011.1 EIM91652.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 1 1 2 2 2 0 EspG family TPR_10 PF13374.1 EIM91653.1 - 2.2e-140 453.2 12.3 8.9e-14 50.8 0.0 12.0 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 EIM91653.1 - 1e-136 445.1 26.7 1.3e-15 57.1 0.1 9.6 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91653.1 - 9.3e-35 115.6 15.9 0.031 14.0 0.0 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91653.1 - 4.3e-29 98.2 5.9 0.18 12.1 0.0 11.1 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91653.1 - 1.4e-23 80.8 12.2 0.41 10.6 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91653.1 - 3.2e-23 80.3 15.7 0.43 10.2 0.0 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91653.1 - 1.2e-22 80.0 5.4 0.0029 18.2 0.0 7.9 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_4 PF07721.9 EIM91653.1 - 4.7e-22 76.0 1.1 0.56 10.7 0.1 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91653.1 - 4.4e-17 62.1 0.3 0.3 11.4 0.0 9.4 1 1 10 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91653.1 - 2.4e-13 49.4 15.5 9.1 7.2 0.0 10.4 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91653.1 - 9.1e-11 41.2 8.6 0.19 11.4 0.0 7.7 4 3 1 7 7 7 3 TPR repeat Rab5-bind PF09311.6 EIM91653.1 - 7.4e-09 35.7 6.6 11 5.8 0.0 8.5 1 1 8 10 10 10 0 Rabaptin-like protein TPR_3 PF07720.7 EIM91653.1 - 6.8e-07 28.9 0.9 4.9 7.0 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM91653.1 - 3.7e-06 26.3 17.5 42 4.2 0.0 10.4 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF59 PF01883.14 EIM91653.1 - 4.7e-05 23.3 0.0 51 3.9 0.0 7.3 9 0 0 9 9 9 0 Domain of unknown function DUF59 ChlamPMP_M PF07548.6 EIM91653.1 - 0.011 15.5 2.6 2.8 7.6 0.1 3.9 2 1 1 4 4 4 0 Chlamydia polymorphic membrane protein middle domain COPR5 PF15340.1 EIM91653.1 - 0.06 13.7 0.5 51 4.2 0.0 4.1 2 2 3 5 5 5 0 Cooperator of PRMT5 family Peptidase_S28 PF05577.7 EIM91653.1 - 0.077 11.5 0.1 16 3.9 0.0 3.8 2 1 3 5 5 5 0 Serine carboxypeptidase S28 PPR PF01535.15 EIM91653.1 - 0.096 12.7 4.5 92 3.3 0.0 6.4 11 0 0 11 11 6 0 PPR repeat Patatin PF01734.17 EIM91654.1 - 1.7e-22 80.3 0.0 2.3e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase LolA PF03548.10 EIM91655.1 - 0.055 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Pkinase PF00069.20 EIM91658.1 - 4.4e-16 58.8 0.0 2.8e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91658.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_10 PF13374.1 EIM91659.1 - 1.2e-80 263.4 0.0 3.5e-10 39.4 0.0 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIM91659.1 - 7.7e-68 224.4 0.8 1e-13 50.9 0.0 5.2 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91659.1 - 1.3e-22 77.7 3.8 0.026 14.2 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91659.1 - 3.8e-15 54.7 0.7 0.57 10.5 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91659.1 - 2.4e-13 49.0 0.2 0.92 9.2 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91659.1 - 3e-12 45.4 0.2 2.1 8.4 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91659.1 - 7.8e-11 42.3 0.0 0.25 12.0 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91659.1 - 6.2e-08 32.6 0.2 12 6.8 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91659.1 - 1.3e-07 31.8 0.0 9.1 6.7 0.0 6.0 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIM91659.1 - 4e-07 29.8 0.0 12 6.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EIM91659.1 - 6.1e-06 26.2 0.7 0.32 10.8 0.1 5.0 1 1 4 5 5 5 1 Rabaptin-like protein Pyr_redox PF00070.22 EIM91659.1 - 5.1e-05 23.6 4.7 45 4.5 0.0 5.9 4 2 2 6 6 6 0 Pyridine nucleotide-disulphide oxidoreductase DUF3268 PF11672.3 EIM91659.1 - 0.00024 21.1 0.1 26 4.9 0.0 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3268) DUF2664 PF10867.3 EIM91659.1 - 0.00054 20.5 4.0 19 5.9 0.0 5.7 3 2 3 6 6 6 0 Protein of unknown function (DUF2664) DUF1924 PF09086.6 EIM91659.1 - 0.0019 18.2 1.0 18 5.4 0.0 5.0 1 1 5 6 6 6 0 Domain of unknown function (DUF1924) TPR_3 PF07720.7 EIM91659.1 - 0.0074 16.0 0.0 2.6 7.9 0.0 4.2 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF3400 PF11880.3 EIM91659.1 - 0.0078 15.4 6.0 11 5.3 0.0 5.1 6 0 0 6 6 5 0 Domain of unknown function (DUF3400) TPR_8 PF13181.1 EIM91659.1 - 0.0095 15.6 2.6 41 4.2 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF59 PF01883.14 EIM91659.1 - 0.016 15.1 0.0 6.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF59 Vel1p PF10339.4 EIM91659.1 - 0.055 12.6 0.1 8.4 5.4 0.0 3.0 1 1 1 3 3 3 0 Yeast-specific zinc responsive Phage_Gp19 PF09355.5 EIM91659.1 - 0.066 13.0 2.1 18 5.2 0.0 3.6 1 1 3 4 4 4 0 Phage protein Gp19/Gp15/Gp42 TPR_6 PF13174.1 EIM91659.1 - 0.14 12.6 8.2 46 4.7 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3157 PF11355.3 EIM91659.1 - 0.15 11.3 3.1 14 4.9 0.1 3.1 1 1 0 3 3 3 0 Protein of unknown function (DUF3157) Pkinase PF00069.20 EIM91661.1 - 9.8e-23 80.6 0.0 2.8e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIM91661.1 - 0.00039 19.5 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIM91661.1 - 0.001 18.2 0.0 0.23 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_10 PF13374.1 EIM91662.1 - 5.5e-123 397.9 0.1 1.8e-11 43.5 0.0 11.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 EIM91662.1 - 9.4e-98 320.2 7.7 3.4e-14 52.5 0.0 9.0 2 2 7 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91662.1 - 1.4e-31 105.7 13.4 0.0062 16.2 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 EIM91662.1 - 4.8e-25 85.6 2.1 0.41 10.9 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91662.1 - 4.4e-18 64.0 4.6 2.3 7.9 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91662.1 - 1.1e-17 62.3 4.9 2.2 8.3 0.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91662.1 - 2.8e-15 56.5 0.0 0.89 10.3 0.0 8.3 2 2 7 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIM91662.1 - 3.9e-14 51.8 6.2 9.1 7.2 0.0 9.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIM91662.1 - 4e-12 45.3 0.0 8.5 7.1 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91662.1 - 4.5e-12 46.1 0.0 6.3 7.2 0.0 8.6 6 2 3 10 10 9 1 Tetratricopeptide repeat DUF59 PF01883.14 EIM91662.1 - 3.6e-07 30.0 0.2 7.5 6.6 0.0 6.9 9 0 0 9 9 8 2 Domain of unknown function DUF59 DUF2664 PF10867.3 EIM91662.1 - 6.7e-05 23.4 10.2 11 6.6 0.0 8.1 5 4 5 10 10 10 0 Protein of unknown function (DUF2664) DUF3268 PF11672.3 EIM91662.1 - 0.00036 20.5 0.3 43 4.2 0.0 6.8 4 4 3 9 9 9 0 Protein of unknown function (DUF3268) TPR_8 PF13181.1 EIM91662.1 - 0.00046 19.7 10.8 36 4.4 0.0 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM91662.1 - 0.00053 20.2 12.8 29 5.3 0.0 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF1924 PF09086.6 EIM91662.1 - 0.00082 19.3 1.0 37 4.4 0.0 5.6 2 2 4 7 7 7 0 Domain of unknown function (DUF1924) DNA_pol_E_B PF04042.11 EIM91662.1 - 0.0073 15.5 0.0 24 4.0 0.0 5.0 1 1 4 6 6 6 0 DNA polymerase alpha/epsilon subunit B zf-Mss51 PF13824.1 EIM91662.1 - 0.018 14.8 1.9 73 3.3 0.0 6.2 9 0 0 9 9 9 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_5 PF12688.2 EIM91662.1 - 0.036 14.0 0.1 51 3.9 0.0 4.7 2 1 4 7 7 7 0 Tetratrico peptide repeat Patatin PF01734.17 EIM91663.1 - 1.2e-13 51.4 0.0 1.2e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.13 EIM91664.1 - 6.9e-24 84.1 0.1 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3995 PF13160.1 EIM91664.1 - 0.048 13.7 0.0 1.6 8.7 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3995) S10_plectin PF03501.10 EIM91665.1 - 3.3e-43 145.4 0.3 4e-43 145.2 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EIM91665.1 - 0.0052 16.4 0.0 0.009 15.7 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Glyco_hydro_61 PF03443.9 EIM91666.1 - 2.3e-76 256.4 5.4 3.1e-76 256.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 HNH_2 PF13391.1 EIM91667.1 - 5.4e-09 35.6 0.0 1.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EIM91669.1 - 3.4e-18 65.7 0.0 4.4e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIM91669.1 - 3.9e-05 23.4 0.1 0.0013 18.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIM91669.1 - 0.00064 18.7 0.0 0.00088 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIM91669.1 - 0.0032 16.8 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EIM91669.1 - 0.0071 15.5 0.0 0.0093 15.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EIM91669.1 - 0.041 12.9 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EIM91669.1 - 0.043 12.8 0.1 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Melibiase PF02065.13 EIM91672.1 - 1e-14 54.0 0.0 1.8e-08 33.5 0.0 2.7 2 1 0 2 2 2 2 Melibiase Fungal_trans PF04082.13 EIM91674.1 - 2.7e-34 118.2 0.0 4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91674.1 - 3.5e-09 36.4 9.7 6.9e-09 35.4 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.2 EIM91676.1 - 6.6e-10 38.3 0.7 0.013 15.0 0.2 5.0 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIM91676.1 - 1e-07 31.2 1.5 0.01 15.8 0.3 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 EIM91676.1 - 8.9e-07 28.1 5.8 0.041 13.9 0.3 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EIM91676.1 - 5.8e-06 25.6 10.5 0.042 14.0 0.3 5.9 7 0 0 7 7 7 2 Leucine rich repeat LRR_8 PF13855.1 EIM91676.1 - 0.00026 20.6 0.6 0.38 10.5 0.1 4.2 4 0 0 4 4 4 1 Leucine rich repeat Melibiase PF02065.13 EIM91677.1 - 7.4e-15 54.5 0.0 1.4e-08 33.8 0.0 2.8 2 1 0 2 2 2 2 Melibiase Methyltrans_Mon PF14314.1 EIM91679.1 - 0.023 12.5 0.0 0.024 12.5 0.0 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase Topo-VIb_trans PF09239.6 EIM91679.1 - 0.12 11.8 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer TPR_12 PF13424.1 EIM91680.1 - 6.7e-08 32.3 8.8 0.0021 17.9 0.1 5.1 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91680.1 - 4.3e-07 29.4 7.8 0.002 17.7 0.1 4.2 3 1 3 6 6 5 2 TPR repeat TPR_14 PF13428.1 EIM91680.1 - 1.7e-06 28.0 6.0 0.0031 18.0 0.0 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91680.1 - 3.4e-06 26.5 3.0 0.0062 16.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM91680.1 - 0.00017 21.0 6.9 0.0051 16.3 0.2 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIM91680.1 - 0.00023 21.7 2.8 1.4 9.6 0.2 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM91680.1 - 0.0072 16.6 1.5 3 8.2 0.6 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIM91680.1 - 0.033 14.6 0.7 14 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIM91680.1 - 0.082 13.0 1.7 4.6 7.4 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIM91680.1 - 0.15 11.9 6.2 0.47 10.3 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIM91680.1 - 0.2 11.6 3.2 23 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 EIM91681.1 - 0.0075 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Ifi-6-16 PF06140.8 EIM91683.1 - 6.1e-05 22.7 31.8 6.1e-05 22.7 22.0 1.8 2 1 0 2 2 2 1 Interferon-induced 6-16 family DUF3481 PF11980.3 EIM91683.1 - 0.088 12.6 0.6 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) NTP_transf_2 PF01909.18 EIM91684.1 - 1.7e-06 28.2 0.1 3.1e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain Arm PF00514.18 EIM91684.1 - 0.14 12.0 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Sec34 PF04136.10 EIM91685.1 - 2e-30 105.5 0.0 4.3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family DUF87 PF01935.12 EIM91687.1 - 0.074 12.8 0.1 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1752 PF08550.5 EIM91688.1 - 3.5e-13 48.8 1.2 4.2e-13 48.6 0.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cellulase PF00150.13 EIM91689.1 - 1.4e-47 162.2 0.1 1.9e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EIM91689.1 - 3.5e-12 45.7 5.5 3.5e-12 45.7 3.8 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 EIM91689.1 - 0.091 11.2 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_10 PF00331.15 EIM91690.1 - 3.8e-55 187.1 0.0 4.4e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase PF00150.13 EIM91690.1 - 0.0054 15.9 0.0 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIM91690.1 - 0.095 13.1 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-binding cellulase-like Cu-oxidase PF00394.17 EIM91692.1 - 1e-38 132.7 0.0 7e-36 123.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM91692.1 - 2e-30 105.0 1.0 1.6e-28 98.9 0.0 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM91692.1 - 9.9e-28 96.2 0.0 2.3e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Ras PF00071.17 EIM91692.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ras family Cu-oxidase_3 PF07732.10 EIM91693.1 - 5.8e-19 67.9 0.0 8.7e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cupin_2 PF07883.6 EIM91694.1 - 5.5e-25 86.6 0.0 1.9e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EIM91694.1 - 1e-21 76.8 0.0 8.6e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EIM91694.1 - 6.9e-09 34.9 0.0 0.0028 16.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EIM91694.1 - 1.4e-05 24.7 0.1 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EIM91694.1 - 0.00037 20.1 0.0 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.7 EIM91694.1 - 0.0032 16.7 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein ARD PF03079.9 EIM91694.1 - 0.014 15.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 EIM91694.1 - 0.092 12.1 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase SSP160 PF06933.6 EIM91694.1 - 2.6 5.9 10.1 3.7 5.4 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dyp_perox PF04261.7 EIM91696.1 - 1.8e-06 26.9 0.0 6.5e-06 25.0 0.0 2.1 2 1 0 2 2 2 1 Dyp-type peroxidase family Exo_endo_phos PF03372.18 EIM91698.1 - 8.3e-14 52.1 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIM91698.1 - 0.0085 15.6 0.0 0.034 13.7 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2201_N PF13203.1 EIM91699.1 - 0.69 9.0 4.0 1.1 8.3 2.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain LRR_8 PF13855.1 EIM91701.1 - 2.3e-17 62.4 9.8 6.7e-10 38.5 0.8 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIM91701.1 - 9.3e-17 60.2 14.3 2e-08 33.6 2.1 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIM91701.1 - 7e-06 25.3 2.6 1 9.6 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EIM91701.1 - 0.00017 21.2 2.0 2 8.9 0.0 4.3 4 0 0 4 4 4 2 Leucine rich repeat BRICHOS PF04089.9 EIM91701.1 - 0.084 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 BRICHOS domain LRR_6 PF13516.1 EIM91701.1 - 0.57 10.4 3.1 32 5.0 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Fungal_trans PF04082.13 EIM91702.1 - 6.5e-25 87.4 0.0 1.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM91702.1 - 1.2e-08 34.7 10.2 2.3e-08 33.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA PF00512.20 EIM91702.1 - 0.14 12.1 0.4 14 5.7 0.0 2.7 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain DivIC PF04977.10 EIM91703.1 - 0.013 14.9 15.6 0.034 13.6 3.2 2.9 3 0 0 3 3 3 0 Septum formation initiator DUF1635 PF07795.6 EIM91703.1 - 0.025 13.9 5.9 0.044 13.1 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CENP-F_leu_zip PF10473.4 EIM91703.1 - 2.7 7.8 18.8 0.14 12.0 8.1 2.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyr_redox_3 PF13738.1 EIM91705.1 - 3.8e-10 40.1 0.0 6.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM91705.1 - 0.00026 20.9 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.1 EIM91705.1 - 0.00056 20.0 0.1 0.0041 17.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Pyr_redox PF00070.22 EIM91705.1 - 0.0048 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM91705.1 - 0.037 12.9 0.0 0.19 10.6 0.0 2.2 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIM91706.1 - 4.8e-18 65.9 0.0 9.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM91706.1 - 3.7e-09 36.4 0.1 1.1e-07 31.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIM91706.1 - 7.5e-08 32.3 0.0 2.9e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM91706.1 - 2.5e-07 30.7 0.2 0.0023 17.8 0.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM91706.1 - 4.2e-05 22.6 0.1 0.00061 18.7 0.3 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIM91706.1 - 0.00018 20.7 0.1 0.013 14.6 0.0 2.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIM91706.1 - 0.0014 18.9 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM91706.1 - 0.0063 15.4 0.1 1.1 8.1 0.0 3.4 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIM91706.1 - 0.07 11.3 0.0 8.7 4.4 0.0 2.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Strep_67kDa_ant PF06100.6 EIM91706.1 - 0.086 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_oxidored PF12831.2 EIM91706.1 - 0.088 11.8 0.4 0.12 11.3 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIM91707.1 - 9.9e-21 74.7 0.0 1.6e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM91707.1 - 5.6e-15 54.5 0.2 1.3e-14 53.3 0.0 1.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIM91707.1 - 7.7e-10 38.6 0.0 9e-09 35.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIM91707.1 - 8.2e-07 28.2 0.5 9.2e-05 21.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM91707.1 - 3.6e-05 23.7 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIM91707.1 - 0.00043 19.3 0.0 0.00089 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIM91707.1 - 0.0015 18.3 0.2 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIM91707.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIM91707.1 - 0.1 11.4 0.0 0.21 10.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DUF936 PF06075.7 EIM91708.1 - 4.2e-05 22.6 19.7 4.6e-05 22.5 13.6 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) Borrelia_P83 PF05262.6 EIM91708.1 - 0.18 10.0 27.4 0.22 9.7 19.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DNA_pol_viral_N PF00242.12 EIM91708.1 - 0.46 9.4 21.0 0.62 9.0 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PLRV_ORF5 PF01690.12 EIM91708.1 - 1.3 8.0 21.4 1.7 7.6 14.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Parvo_coat PF00740.13 EIM91708.1 - 1.9 7.3 13.9 2.4 7.0 9.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 APG6 PF04111.7 EIM91708.1 - 2.2 7.2 17.6 3.3 6.6 12.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp-B-Hydro_N PF05279.6 EIM91708.1 - 2.2 8.0 23.1 3.5 7.4 16.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.4 EIM91708.1 - 2.5 6.6 32.6 3.6 6.1 22.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribonuclease_3 PF00636.21 EIM91708.1 - 6.9 7.1 17.9 2.7e+02 2.0 12.4 2.7 1 1 0 1 1 1 0 Ribonuclease III domain RVT_3 PF13456.1 EIM91711.1 - 0.013 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.17 EIM91712.1 - 0.052 13.2 0.0 0.21 11.2 0.0 2.0 1 1 1 2 2 2 0 Phage integrase family MFS_1 PF07690.11 EIM91713.1 - 1e-29 103.3 31.9 1.2e-29 103.1 22.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_C_2 PF13410.1 EIM91714.1 - 9.9e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM91714.1 - 4.9e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM91714.1 - 1.3e-05 25.5 0.0 3.5e-05 24.2 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM91714.1 - 0.00058 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIM91714.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rotamase PF00639.16 EIM91715.1 - 2.9e-23 82.4 0.0 3.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIM91715.1 - 8.5e-22 77.6 0.0 1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EIM91715.1 - 2.2e-07 30.5 0.9 3.2e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EIM91715.1 - 2.3e-06 28.2 0.0 2.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Adenyl_cycl_N PF12633.2 EIM91716.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase NT domain Aldedh PF00171.17 EIM91718.1 - 3.5e-181 602.5 0.0 4e-181 602.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM91718.1 - 3.9e-06 25.8 0.0 6.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1411 PF07199.6 EIM91718.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) zf-MYND PF01753.13 EIM91719.1 - 2.6e-05 23.9 11.7 2.6e-05 23.9 8.1 1.9 2 0 0 2 2 2 1 MYND finger Transp_Tc5_C PF04236.10 EIM91719.1 - 0.075 13.2 2.0 0.16 12.2 1.4 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-HIT PF04438.11 EIM91719.1 - 0.078 12.6 9.4 0.15 11.7 6.5 1.5 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.11 EIM91720.1 - 1.5e-28 99.5 51.6 7.4e-23 80.8 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91720.1 - 5.4e-07 28.5 35.2 0.00031 19.4 7.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Aldedh PF00171.17 EIM91722.1 - 1.3e-182 607.2 0.0 1.5e-182 607.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM91722.1 - 0.00089 18.0 0.0 0.002 16.9 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 EIM91723.1 - 1e-183 610.9 0.0 1.2e-183 610.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM91723.1 - 0.0019 16.9 0.0 0.005 15.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) FtsA PF14450.1 EIM91723.1 - 0.11 12.3 0.1 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsA AAA_10 PF12846.2 EIM91724.1 - 8.4e-10 38.5 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EIM91724.1 - 1e-05 25.0 0.1 2.8e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EIM91724.1 - 0.015 15.5 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM91724.1 - 0.021 14.9 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EIM91724.1 - 0.095 12.1 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase zf-MYND PF01753.13 EIM91725.1 - 1.6e-06 27.8 9.9 3.5e-06 26.7 6.9 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EIM91725.1 - 0.1 12.2 7.9 0.22 11.2 5.5 1.5 1 0 0 1 1 1 0 HIT zinc finger Aldedh PF00171.17 EIM91726.1 - 2.4e-180 599.8 0.3 2.7e-180 599.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM91726.1 - 0.00016 20.5 0.0 0.00075 18.3 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) AAA_10 PF12846.2 EIM91727.1 - 4.3e-10 39.5 0.1 4e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EIM91727.1 - 8.6e-06 25.3 0.2 3.5e-05 23.3 0.0 2.0 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA PF00004.24 EIM91727.1 - 0.0062 16.7 0.1 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM91727.1 - 0.021 14.9 0.1 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EIM91728.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein F-box-like PF12937.2 EIM91730.1 - 0.02 14.5 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Kdo PF06293.9 EIM91731.1 - 0.0067 15.5 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EIM91733.1 - 2.6e-37 127.7 0.0 3.2e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM91733.1 - 7.4e-17 61.9 0.0 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM91733.1 - 3.3e-07 29.7 0.0 4.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM91733.1 - 4.1e-05 22.8 0.0 6.7e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM91733.1 - 0.00013 21.4 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIM91733.1 - 0.00077 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIM91733.1 - 0.0028 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EIM91733.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM91733.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 F-box-like PF12937.2 EIM91734.1 - 0.0052 16.4 0.9 0.013 15.2 0.2 2.1 2 1 0 2 2 2 1 F-box-like HNH_2 PF13391.1 EIM91736.1 - 0.022 14.5 0.1 0.086 12.6 0.1 2.0 1 1 0 1 1 1 0 HNH endonuclease DEAD PF00270.24 EIM91737.1 - 8e-20 71.0 0.0 6.5e-11 42.0 0.0 3.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM91737.1 - 6.1e-12 45.2 0.0 2.9e-11 43.0 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM91737.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IncA PF04156.9 EIM91738.1 - 0.084 12.4 0.2 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 IncA protein DUF2040 PF09745.4 EIM91738.1 - 3.7 7.3 13.2 7.1 6.4 9.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) BTB PF00651.26 EIM91739.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.13 EIM91741.1 - 1e-09 38.0 14.2 1.8e-09 37.3 9.8 1.4 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 EIM91741.1 - 0.0076 16.5 0.0 0.049 13.9 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM91741.1 - 0.016 15.7 0.0 21 5.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 EIM91741.1 - 0.027 14.2 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 EIM91741.1 - 0.064 13.5 0.1 12 6.3 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) LRR_8 PF13855.1 EIM91742.1 - 0.038 13.7 3.6 0.14 11.9 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat Pyr_redox_3 PF13738.1 EIM91743.1 - 1e-20 74.6 0.0 1.4e-19 71.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM91743.1 - 1.2e-18 66.5 0.2 5.2e-13 48.0 0.1 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM91743.1 - 9.1e-16 57.6 0.0 1.2e-09 37.5 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM91743.1 - 5.4e-11 42.7 0.0 8.2e-09 35.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIM91743.1 - 8.5e-07 29.2 0.0 0.013 15.8 0.0 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIM91743.1 - 0.00032 20.3 0.0 0.037 13.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIM91743.1 - 0.001 18.2 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EIM91743.1 - 0.0043 15.9 0.1 0.14 11.0 0.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIM91743.1 - 0.0084 16.1 0.0 0.058 13.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIM91743.1 - 0.011 14.8 0.1 0.38 9.8 0.0 2.5 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.14 EIM91743.1 - 0.013 14.5 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EIM91743.1 - 0.026 12.9 0.0 0.16 10.3 0.0 2.3 4 0 0 4 4 4 0 HI0933-like protein Lycopene_cycl PF05834.7 EIM91743.1 - 0.15 10.9 0.0 2 7.2 0.0 2.6 4 0 0 4 4 4 0 Lycopene cyclase protein Cep57_MT_bd PF06657.8 EIM91744.1 - 0.004 17.0 2.9 0.33 10.9 0.2 2.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Tropomyosin_1 PF12718.2 EIM91744.1 - 0.0044 16.8 3.8 0.031 14.1 0.7 2.3 2 0 0 2 2 2 1 Tropomyosin like DUF904 PF06005.7 EIM91744.1 - 0.0081 16.4 5.7 0.98 9.7 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF904) PspA_IM30 PF04012.7 EIM91744.1 - 0.018 14.4 10.2 0.052 12.8 7.1 1.7 1 1 0 1 1 1 0 PspA/IM30 family IL2 PF00715.12 EIM91744.1 - 0.031 13.9 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 DP PF08781.5 EIM91744.1 - 0.034 13.8 0.1 0.092 12.4 0.1 1.7 1 0 0 1 1 1 0 Transcription factor DP DUF4407 PF14362.1 EIM91744.1 - 0.056 12.3 0.5 0.078 11.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.7 EIM91744.1 - 0.12 10.8 0.6 0.16 10.4 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc24 PF08286.6 EIM91744.1 - 0.16 11.6 1.5 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 EIM91744.1 - 0.21 10.4 3.8 0.58 9.0 2.7 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EIM91744.1 - 0.35 10.8 9.4 4.7 7.2 0.2 3.0 3 0 0 3 3 3 0 bZIP transcription factor DUF4140 PF13600.1 EIM91744.1 - 0.52 10.7 7.4 37 4.8 5.1 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 EIM91744.1 - 0.71 9.7 10.6 1.6 8.6 1.5 3.2 3 0 0 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 EIM91744.1 - 1 9.2 8.2 1.5 8.6 1.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EIM91744.1 - 1.2 8.9 9.1 3.6 7.3 0.5 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EIM91744.1 - 1.6 8.6 7.2 4.1 7.2 1.5 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 EIM91744.1 - 1.6 8.3 5.6 0.3 10.7 1.4 1.5 2 0 0 2 2 2 0 Mnd1 family DUF4200 PF13863.1 EIM91744.1 - 2.3 8.1 10.2 2.6 7.9 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.7 EIM91744.1 - 2.9 7.6 6.3 2.7 7.7 1.0 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) KfrA_N PF11740.3 EIM91744.1 - 4.2 7.8 8.1 0.64 10.4 0.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.1 EIM91745.1 - 0.00046 19.2 2.8 0.00072 18.5 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 EIM91745.1 - 0.029 14.1 1.2 0.029 14.1 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 EIM91745.1 - 0.03 13.6 4.0 0.049 12.9 2.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EIM91745.1 - 0.062 11.7 1.2 0.078 11.4 0.9 1.2 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 EIM91745.1 - 0.067 13.5 0.7 0.067 13.5 0.5 2.2 2 0 0 2 2 2 0 SlyX Osmo_CC PF08946.5 EIM91745.1 - 0.09 12.8 1.0 0.23 11.5 0.7 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Fib_alpha PF08702.5 EIM91745.1 - 0.29 11.2 2.5 0.62 10.1 1.4 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EIM91745.1 - 0.39 11.0 6.2 0.29 11.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIM91745.1 - 0.51 9.8 6.6 0.059 12.8 1.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 EIM91745.1 - 1.4 7.7 12.0 2.1 7.2 5.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EIM91745.1 - 3.6 6.7 9.8 2.4 7.3 0.2 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EIM91745.1 - 4.6 7.2 11.9 2.1 8.3 3.6 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.6 EIM91745.1 - 5.2 7.0 7.7 2.2 8.2 0.3 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 EIM91746.1 - 0.00015 21.5 0.2 0.52 10.2 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat p450 PF00067.17 EIM91747.1 - 6.4e-64 216.1 0.0 7.3e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAF1_ABF1 PF04684.8 EIM91747.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_C14 PF00656.17 EIM91748.1 - 1.9e-14 53.9 0.0 3.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Herpes_UL37_2 PF07413.6 EIM91748.1 - 0.039 12.7 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 IU_nuc_hydro PF01156.14 EIM91749.1 - 8.2e-53 179.6 0.0 1.1e-52 179.2 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GMC_oxred_N PF00732.14 EIM91750.1 - 8.9e-45 153.0 1.2 1.3e-25 90.1 0.1 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM91750.1 - 5.8e-12 46.1 0.0 1.3e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM91750.1 - 9.6e-06 24.6 0.1 0.0011 17.8 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EIM91750.1 - 1.6e-05 24.0 0.2 0.00018 20.5 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91750.1 - 4.1e-05 23.5 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM91750.1 - 0.00026 20.9 0.1 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIM91750.1 - 0.00031 19.7 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIM91750.1 - 0.0049 16.9 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIM91750.1 - 0.055 12.5 0.1 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIM91750.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding F-box-like PF12937.2 EIM91751.1 - 0.00045 19.8 0.6 0.00082 19.0 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91751.1 - 0.058 13.0 0.6 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 F-box domain Peptidase_C14 PF00656.17 EIM91753.1 - 6.2e-14 52.2 0.0 1.7e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Peptidase_C54 PF03416.14 EIM91754.1 - 2.5e-84 282.7 0.0 1e-71 241.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C54 F-box-like PF12937.2 EIM91755.1 - 5.1e-05 22.9 0.5 0.00013 21.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91755.1 - 0.0091 15.6 0.6 0.45 10.2 0.1 2.6 2 0 0 2 2 2 1 F-box domain GMC_oxred_C PF05199.8 EIM91756.1 - 2e-12 47.5 0.1 2.4e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM91757.1 - 0.0041 17.4 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIM91759.1 - 9.9e-40 136.5 3.7 1.3e-25 90.2 0.1 3.1 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM91759.1 - 3.9e-26 92.0 0.0 8.5e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM91759.1 - 1.5e-05 24.0 0.6 0.00014 20.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIM91759.1 - 3.8e-05 22.7 0.5 0.00015 20.7 0.0 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91759.1 - 0.00013 21.9 0.0 0.0007 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM91759.1 - 0.00079 18.4 0.1 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIM91759.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Grp1_Fun34_YaaH PF01184.14 EIM91761.1 - 5.6e-60 202.2 16.8 6.7e-60 201.9 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3796 PF12676.2 EIM91761.1 - 1.9 8.7 7.1 1.3 9.3 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3796) DUF3040 PF11239.3 EIM91761.1 - 4.3 7.4 8.5 13 5.8 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Grp1_Fun34_YaaH PF01184.14 EIM91762.1 - 1.5e-63 213.9 15.7 1.8e-63 213.6 10.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Peptidase_S64 PF08192.6 EIM91763.1 - 0.0013 17.1 0.0 0.0017 16.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Acetyltransf_3 PF13302.1 EIM91764.1 - 1.8e-19 70.2 0.0 3.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM91764.1 - 3.8e-07 30.1 0.3 0.036 13.9 0.0 3.1 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM91764.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 EIM91764.1 - 0.01 15.8 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF3535 PF12054.3 EIM91764.1 - 0.023 13.3 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Acetyltransf_4 PF13420.1 EIM91764.1 - 0.16 11.9 1.2 0.27 11.1 0.0 1.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Alpha-L-AF_C PF06964.7 EIM91767.1 - 9.2e-44 149.3 0.1 1.6e-43 148.5 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Pyr_redox_3 PF13738.1 EIM91768.1 - 1.1e-23 84.3 0.0 7.8e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIM91768.1 - 2.1e-16 59.2 0.0 9.4e-16 57.0 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIM91768.1 - 1e-12 47.6 0.0 9.2e-06 24.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIM91768.1 - 6.2e-10 39.3 0.0 3.3e-05 24.2 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM91768.1 - 2.8e-09 37.1 0.0 2.6e-08 34.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIM91768.1 - 2.8e-05 24.0 0.0 0.00087 19.2 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIM91768.1 - 6.7e-05 22.1 0.3 0.001 18.2 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EIM91768.1 - 0.00015 20.8 0.6 0.0003 19.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIM91768.1 - 0.00019 20.4 0.1 0.0017 17.3 0.0 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 EIM91768.1 - 0.0005 19.0 0.2 0.01 14.7 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIM91768.1 - 0.00061 18.9 0.0 0.0061 15.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EIM91768.1 - 0.0015 17.6 0.0 0.16 11.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.7 EIM91768.1 - 0.0021 17.0 0.0 0.0058 15.5 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EIM91768.1 - 0.0028 17.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIM91768.1 - 0.003 16.1 0.0 0.0082 14.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EIM91768.1 - 0.0035 17.1 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EIM91768.1 - 0.015 15.3 0.0 0.78 9.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIM91768.1 - 0.052 13.5 0.1 0.22 11.5 0.0 2.1 3 0 0 3 3 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EIM91768.1 - 0.066 13.4 0.0 2.1 8.6 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIM91768.1 - 0.087 11.8 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase IlvN PF07991.7 EIM91768.1 - 0.11 11.9 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF1378 PF07125.6 EIM91768.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) HNH_2 PF13391.1 EIM91769.1 - 0.00043 20.0 0.0 0.0009 18.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease But2 PF09792.4 EIM91770.1 - 0.0046 16.7 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EIM91771.1 - 4.4e-18 65.7 4.1 7e-18 65.1 2.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EIM91775.1 - 1.5e-19 70.5 0.0 1.8e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HNH_2 PF13391.1 EIM91777.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Mem_trans PF03547.13 EIM91778.1 - 1.1e-33 116.0 0.0 1.9e-33 115.3 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein UCH PF00443.24 EIM91779.1 - 9.2e-46 156.1 0.0 2.2e-45 154.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EIM91779.1 - 1.3e-26 91.6 0.2 6.9e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EIM91779.1 - 2e-26 91.8 11.8 2.7e-20 72.2 0.4 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EIM91779.1 - 1e-12 48.1 0.0 8.7e-11 41.7 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HSP70 PF00012.15 EIM91780.1 - 9.8e-54 182.2 0.4 2.9e-36 124.5 0.0 2.6 3 0 0 3 3 3 2 Hsp70 protein F-box-like PF12937.2 EIM91781.1 - 4.8e-05 23.0 0.2 4.8e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM91782.1 - 2.3e-05 23.9 0.1 0.00012 21.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like Kri1_C PF12936.2 EIM91782.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 KRI1-like family C-terminal REJ PF02010.10 EIM91782.1 - 0.18 10.0 0.0 0.27 9.5 0.0 1.2 1 0 0 1 1 1 0 REJ domain RapA_C PF12137.3 EIM91786.1 - 0.083 11.7 0.0 10 4.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal MDFI PF15316.1 EIM91786.1 - 0.2 11.6 0.0 27 4.6 0.0 2.3 2 0 0 2 2 2 0 MyoD family inhibitor Med12-LCEWAV PF12145.3 EIM91786.1 - 2 6.7 10.6 3.7 5.9 1.3 2.1 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain zf-4CXXC_R1 PF10497.4 EIM91787.1 - 1.6e-06 28.2 17.1 3.2e-06 27.2 11.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Tannase PF07519.6 EIM91790.1 - 1.3e-90 304.4 0.0 6.2e-90 302.1 0.0 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EIM91790.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold RPN7 PF10602.4 EIM91791.1 - 0.038 13.3 0.1 0.081 12.2 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 NAP PF00956.13 EIM91794.1 - 1.1e-79 266.9 5.8 1.1e-79 266.9 4.0 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Snapin_Pallidin PF14712.1 EIM91794.1 - 0.028 14.7 0.4 0.028 14.7 0.3 1.9 2 0 0 2 2 2 0 Snapin/Pallidin F-box-like PF12937.2 EIM91795.1 - 3e-15 55.6 14.1 0.00012 21.7 0.9 4.9 4 0 0 4 4 4 4 F-box-like SAE2 PF08573.5 EIM91797.1 - 1.5e-15 57.6 1.2 1.5e-15 57.6 0.9 2.1 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4637 PF15470.1 EIM91797.1 - 0.16 11.5 0.2 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) SOG2 PF10428.4 EIM91797.1 - 1.2 7.6 16.0 1.6 7.2 11.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Luteo_Vpg PF01659.11 EIM91798.1 - 0.31 10.7 2.9 0.49 10.0 2.0 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein F-box-like PF12937.2 EIM91801.1 - 5.9e-09 35.5 0.8 1.5e-08 34.2 0.6 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 EIM91802.1 - 2.2e-24 86.6 0.1 2.9e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM91802.1 - 8.5e-17 61.4 0.2 3.8e-16 59.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIM91802.1 - 1.6e-08 34.4 0.0 3.1e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIM91802.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EIM91802.1 - 0.012 15.3 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase LSM PF01423.17 EIM91803.1 - 2.3e-16 59.1 0.1 2.6e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIM91803.1 - 6.3e-06 26.0 0.2 8.2e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box-like PF12937.2 EIM91804.1 - 1.1e-09 37.8 0.8 2.8e-09 36.5 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EIM91804.1 - 0.037 14.1 0.9 1.1e+02 3.7 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat DUF2834 PF11196.3 EIM91805.1 - 3.4e-05 23.8 18.4 0.05 13.7 5.8 3.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) DUF4181 PF13789.1 EIM91805.1 - 1.3 8.9 6.7 0.72 9.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Zn_clus PF00172.13 EIM91806.1 - 1.1e-08 34.8 10.4 1.7e-08 34.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 EIM91807.1 - 5.2e-166 552.8 0.7 6.5e-166 552.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIM91807.1 - 3.6e-06 26.7 0.0 1.8e-05 24.5 0.0 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.21 EIM91808.1 - 1.4e-165 551.4 2.0 1.8e-165 551.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 EIM91809.1 - 4.7e-165 549.6 1.9 5.9e-165 549.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Aldolase_II PF00596.16 EIM91810.1 - 1.2e-40 139.0 0.0 1.5e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short_C2 PF13561.1 EIM91811.1 - 7.6e-35 120.8 0.0 9e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM91811.1 - 4.9e-18 65.6 1.9 7.1e-18 65.0 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM91811.1 - 2.6e-09 36.9 0.5 3.7e-09 36.5 0.3 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 EIM91811.1 - 0.057 12.6 0.1 0.094 11.9 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein HMG_box PF00505.14 EIM91814.1 - 2.5e-16 59.6 2.4 4.5e-16 58.8 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM91814.1 - 3.4e-14 52.9 1.2 6.4e-14 52.0 0.9 1.4 1 0 0 1 1 1 1 HMG-box domain Cu-oxidase PF00394.17 EIM91817.1 - 6.3e-43 146.4 0.9 1.2e-41 142.2 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM91817.1 - 7.7e-35 119.4 2.3 1.6e-33 115.1 0.6 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM91817.1 - 3.6e-32 110.5 3.1 4e-28 97.5 0.0 3.4 3 0 0 3 3 3 3 Multicopper oxidase Lactamase_B_2 PF12706.2 EIM91818.1 - 3.7e-10 39.6 0.0 0.00041 19.9 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DDE_Tnp_4 PF13359.1 EIM91819.1 - 9.4e-21 74.0 0.0 2.8e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease PAS_3 PF08447.6 EIM91819.1 - 0.034 14.2 0.1 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold O-antigen_lig PF13425.1 EIM91819.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RAP1 PF07218.6 EIM91819.1 - 0.25 9.3 8.6 0.33 9.0 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.4 EIM91819.1 - 0.27 10.0 4.3 0.33 9.7 3.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 EIM91819.1 - 0.77 7.9 4.9 1 7.5 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 EIM91819.1 - 0.83 7.4 20.5 1 7.1 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Med3 PF11593.3 EIM91820.1 - 0.00051 19.3 17.4 0.00051 19.3 12.1 1.5 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DUF493 PF04359.9 EIM91820.1 - 0.024 15.0 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF493) PEMT PF04191.8 EIM91821.1 - 2.8e-30 104.5 2.6 2.8e-30 104.5 1.8 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF95 PF01944.12 EIM91821.1 - 0.12 11.9 1.4 0.29 10.7 0.9 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF95 DUF2422 PF10337.4 EIM91822.1 - 1.4e-68 231.7 9.8 1.7e-66 224.9 6.8 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIM91822.1 - 5.1e-57 193.1 0.1 1e-56 192.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIM91822.1 - 2.2e-08 34.0 17.7 2.2e-08 34.0 12.2 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like GST_N PF02798.15 EIM91823.1 - 8.7e-12 45.0 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM91823.1 - 7.3e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM91823.1 - 4.2e-07 29.8 0.0 6.2e-06 26.1 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM91823.1 - 3.1e-06 27.3 0.0 7.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM91823.1 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIM91823.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIM91825.1 - 6.7e-11 42.2 0.0 9.3e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIM91825.1 - 5.3e-06 26.5 0.0 8.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIM91825.1 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTCB-BRCT PF12738.2 EIM91827.1 - 7.8e-26 89.7 2.9 4e-15 55.4 0.1 5.1 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.21 EIM91827.1 - 1.1e-23 83.1 0.0 2.6e-06 27.4 0.0 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain Mpv17_PMP22 PF04117.7 EIM91828.1 - 5.9e-23 80.2 1.4 9.4e-23 79.6 1.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family V-SNARE PF05008.10 EIM91829.1 - 3.2e-21 75.2 6.8 3.4e-21 75.1 2.7 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EIM91829.1 - 2.7e-16 59.3 7.2 3.5e-16 59.0 3.3 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 EIM91829.1 - 0.0022 15.6 0.8 0.0089 13.6 0.1 1.8 2 0 0 2 2 2 1 Prominin Sec20 PF03908.8 EIM91829.1 - 0.023 14.4 0.8 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 Sec20 DUF1366 PF07104.6 EIM91829.1 - 0.05 13.2 0.9 0.1 12.1 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1366) OppC_N PF12911.2 EIM91829.1 - 0.1 11.9 0.8 0.19 11.1 0.6 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF3225 PF11533.3 EIM91829.1 - 0.11 12.1 1.0 0.17 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) Laminin_I PF06008.9 EIM91829.1 - 0.64 9.2 7.0 0.55 9.5 0.7 2.2 2 0 0 2 2 2 0 Laminin Domain I Prefoldin_2 PF01920.15 EIM91830.1 - 4.1e-22 77.9 12.8 7.5e-22 77.1 8.9 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIM91830.1 - 0.01 15.5 2.7 0.015 15.0 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.4 EIM91830.1 - 0.021 13.7 6.1 0.025 13.5 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EIM91830.1 - 0.049 13.8 6.8 0.054 13.7 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 EIM91830.1 - 0.14 12.5 11.2 0.16 12.3 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIM91830.1 - 0.2 11.2 14.8 0.96 9.0 10.3 1.8 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 EIM91830.1 - 0.32 10.5 12.9 0.25 10.8 0.7 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ada3 PF10198.4 EIM91830.1 - 0.36 10.5 5.2 1.7 8.4 3.1 2.0 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 End3 PF12761.2 EIM91830.1 - 0.84 9.2 7.6 1.7 8.2 5.2 1.6 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Rab5-bind PF09311.6 EIM91830.1 - 0.97 9.2 13.7 0.39 10.5 4.4 2.2 2 0 0 2 2 2 0 Rabaptin-like protein ADIP PF11559.3 EIM91830.1 - 1.4 8.7 13.0 0.19 11.6 4.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FadA PF09403.5 EIM91830.1 - 2.4 8.1 11.5 2.8 7.9 1.7 2.2 1 1 0 2 2 2 0 Adhesion protein FadA Mod_r PF07200.8 EIM91830.1 - 3 7.7 11.9 1 9.2 3.6 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.9 EIM91830.1 - 3.4 7.5 17.6 1.5 8.7 6.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.4 EIM91830.1 - 3.5 7.4 12.8 4.6 7.0 3.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EIM91830.1 - 5.1 6.0 12.5 7.8 5.4 8.1 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 EIM91830.1 - 5.5 6.6 11.7 2.4 7.8 3.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit Macoilin PF09726.4 EIM91830.1 - 8 4.6 9.4 14 3.8 6.5 1.4 1 1 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 EIM91830.1 - 10 5.0 11.3 0.84 8.5 3.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.2 EIM91831.1 - 1.2e-09 37.7 0.5 5.6e-09 35.5 0.3 2.3 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIM91832.1 - 3.6e-08 33.0 7.1 1.8e-07 30.7 4.9 2.3 1 1 0 1 1 1 1 F-box-like BTB PF00651.26 EIM91833.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 EIM91834.1 - 1.5e-08 34.2 0.0 3.8e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM91834.1 - 0.13 11.9 2.2 1.5 8.5 0.1 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIM91835.1 - 2.8e-17 62.1 10.8 1.7e-08 34.0 1.3 2.7 2 0 0 2 2 2 2 F-box-like Oxidored_FMN PF00724.15 EIM91836.1 - 2.4e-42 145.1 0.0 3.1e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fasciclin PF02469.17 EIM91840.1 - 7.1e-32 110.0 1.2 8.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain FKBP_C PF00254.23 EIM91841.1 - 7.9e-18 64.2 0.0 3.1e-16 59.1 0.0 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dabb PF07876.7 EIM91842.1 - 0.0035 17.7 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RabGAP-TBC PF00566.13 EIM91844.1 - 8.1e-31 107.1 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 EIM91844.1 - 0.00084 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BTB PF00651.26 EIM91845.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fer4_21 PF14697.1 EIM91845.1 - 0.016 15.0 2.7 0.3 10.9 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-MYND PF01753.13 EIM91847.1 - 5.7e-09 35.6 14.2 5.7e-09 35.6 9.8 1.6 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.2 EIM91848.1 - 4.8e-07 29.3 2.4 1.6e-06 27.7 1.7 2.0 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EIM91849.1 - 7.3e-74 248.1 0.0 6.9e-71 238.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91849.1 - 7.8e-38 130.0 0.0 1.3e-33 116.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM91849.1 - 8.4e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIM91849.1 - 0.0004 19.7 0.0 0.00097 18.5 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIM91849.1 - 0.0042 16.1 0.1 0.017 14.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2621 PF11084.3 EIM91849.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) F-box-like PF12937.2 EIM91850.1 - 1.9e-07 30.7 2.0 4.8e-07 29.3 1.4 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EIM91851.1 - 6.2e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIM91851.1 - 0.00024 20.4 0.4 0.00052 19.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EIM91851.1 - 0.00033 20.4 0.2 0.00063 19.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EIM91851.1 - 0.0018 17.5 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EIM91851.1 - 0.0051 15.9 0.1 0.014 14.4 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase 2-oxoacid_dh PF00198.18 EIM91852.1 - 1.3e-49 168.5 0.0 4.2e-49 166.9 0.0 1.7 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIM91852.1 - 1.2e-18 66.5 0.7 2.8e-18 65.3 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EIM91852.1 - 8.1e-11 41.3 0.2 3.1e-10 39.4 0.2 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EIM91852.1 - 0.00051 19.6 1.8 0.0011 18.5 0.4 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EIM91852.1 - 0.044 14.1 0.1 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 HlyD family secretion protein Abhydrolase_1 PF00561.15 EIM91853.1 - 3.1e-31 108.6 0.0 6.9e-31 107.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM91853.1 - 1.1e-10 41.7 2.5 2.2e-09 37.5 1.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Terpene_synth_C PF03936.11 EIM91854.1 - 2.5e-10 40.0 0.3 5.3e-10 38.9 0.2 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DHC_N1 PF08385.7 EIM91855.1 - 3.8e-193 643.0 9.1 3.4e-192 639.9 3.4 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 Lipoprotein_6 PF01441.14 EIM91855.1 - 0.087 12.6 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein Cullin PF00888.17 EIM91856.1 - 8.9e-104 348.1 0.0 1.2e-103 347.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIM91856.1 - 1.4e-24 85.6 0.6 4.7e-24 83.9 0.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain adh_short PF00106.20 EIM91857.1 - 1.1e-15 57.9 5.6 1.2e-13 51.3 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIM91857.1 - 2.1e-09 37.3 0.4 2.1e-09 37.3 0.3 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EIM91857.1 - 0.00023 20.8 0.1 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EIM91857.1 - 0.00043 20.1 0.1 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM91857.1 - 0.0082 16.1 0.3 0.015 15.3 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIM91857.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EIM91857.1 - 0.098 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribonucleas_3_3 PF14622.1 EIM91859.1 - 1.5e-15 57.3 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM91859.1 - 0.0038 17.6 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain DUF3328 PF11807.3 EIM91860.1 - 9.6e-19 67.9 0.9 1.1e-18 67.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 EIM91861.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EIM91862.1 - 0.037 13.7 0.3 0.12 11.9 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EIM91863.1 - 2.7e-42 144.7 59.5 9.7e-42 142.9 40.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM91863.1 - 2.9e-11 42.6 13.2 2.9e-11 42.6 9.1 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.14 EIM91866.1 - 2.1e-21 76.3 0.0 3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIM91866.1 - 0.0035 16.3 0.1 0.0073 15.2 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91866.1 - 0.02 14.9 1.6 0.056 13.4 1.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIM91866.1 - 0.036 12.7 0.7 1.9 6.9 0.4 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EIM91866.1 - 0.049 12.7 0.4 0.09 11.8 0.3 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EIM91866.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase MIase PF02426.11 EIM91866.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Muconolactone delta-isomerase DUF3328 PF11807.3 EIM91867.1 - 3.5e-17 62.8 0.9 4.2e-17 62.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EMI PF07546.8 EIM91867.1 - 0.085 13.3 0.3 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 EMI domain Pyr_redox_3 PF13738.1 EIM91868.1 - 3.5e-20 72.9 0.0 6.7e-17 62.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIM91868.1 - 8.8e-16 57.7 0.0 3.9e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIM91868.1 - 2.8e-13 50.2 0.0 1.4e-06 28.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM91868.1 - 2.3e-10 40.4 0.4 0.0051 16.5 0.1 4.0 3 1 0 3 3 3 3 FAD-NAD(P)-binding DAO PF01266.19 EIM91868.1 - 6.8e-10 38.3 1.4 0.054 12.4 0.4 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM91868.1 - 4.8e-09 36.1 0.2 7.6e-06 25.8 0.0 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EIM91868.1 - 1.5e-08 33.3 0.0 1.3e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 EIM91868.1 - 3.2e-08 32.9 0.2 0.00015 20.9 0.0 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EIM91868.1 - 2.8e-06 26.0 0.2 0.69 8.3 0.0 3.9 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox PF00070.22 EIM91868.1 - 2.5e-05 24.6 3.0 0.0013 19.1 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIM91868.1 - 0.00011 21.1 1.4 0.28 9.9 0.0 3.7 4 0 0 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.14 EIM91868.1 - 0.0012 17.9 0.9 0.083 11.9 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EIM91868.1 - 0.0015 17.4 2.3 2 7.1 0.0 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EIM91868.1 - 0.0029 16.7 0.0 1.7 7.6 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIM91868.1 - 0.0038 16.2 0.1 9.8 4.9 0.0 3.5 4 0 0 4 4 4 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EIM91868.1 - 0.008 16.2 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIM91868.1 - 0.015 15.5 0.0 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EIM91868.1 - 0.039 13.6 0.5 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIM91868.1 - 0.08 12.6 0.4 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EIM91868.1 - 0.083 11.9 0.0 6 5.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EIM91868.1 - 0.089 13.2 0.4 10 6.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Mqo PF06039.10 EIM91868.1 - 0.13 10.3 0.0 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.11 EIM91868.1 - 0.19 11.1 0.7 2.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_hydr_30_2 PF14587.1 EIM91869.1 - 1.4e-24 86.7 0.0 6.7e-20 71.3 0.0 2.4 2 1 1 3 3 3 2 O-Glycosyl hydrolase family 30 Thaumatin PF00314.12 EIM91870.1 - 9.6e-25 87.3 1.2 9.6e-25 87.3 0.8 2.0 1 1 1 2 2 2 2 Thaumatin family LRRNT PF01462.13 EIM91870.1 - 0.17 11.3 0.3 0.17 11.3 0.2 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Sulfatase PF00884.18 EIM91872.1 - 1.3e-49 169.0 0.1 1.6e-49 168.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EIM91872.1 - 0.00037 19.9 0.3 0.0074 15.6 0.0 2.3 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF21 PF01595.15 EIM91873.1 - 3.4e-27 94.9 0.2 5e-27 94.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIM91873.1 - 4.3e-08 32.8 0.1 0.00068 19.3 0.0 2.8 3 0 0 3 3 3 2 CBS domain tRNA_U5-meth_tr PF05958.6 EIM91874.1 - 3.8e-15 55.4 0.0 1.5e-14 53.5 0.0 2.1 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EIM91874.1 - 8.3e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EIM91874.1 - 9.8e-06 25.5 0.1 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91874.1 - 2.7e-05 23.8 0.0 4.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91874.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIM91874.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EIM91874.1 - 0.0061 16.1 0.1 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.13 EIM91874.1 - 0.064 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EIM91874.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EIM91874.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S10 PF00450.17 EIM91875.1 - 4.7e-110 368.6 0.0 5.8e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIM91875.1 - 2.3e-06 27.6 0.0 5.9e-05 23.0 0.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 EIM91876.1 - 5.8e-05 23.3 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM91876.1 - 0.0012 19.3 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIM91876.1 - 0.0059 16.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EIM91876.1 - 0.032 14.4 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 EIM91876.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sulfatase PF00884.18 EIM91878.1 - 1.4e-51 175.5 0.2 1.9e-51 175.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EIM91878.1 - 0.0029 16.9 0.1 0.0061 15.9 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Cu-oxidase PF00394.17 EIM91879.1 - 6.5e-40 136.6 0.6 2.8e-35 121.5 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM91879.1 - 4.9e-34 116.8 0.7 4.9e-34 116.8 0.5 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM91879.1 - 6.5e-33 112.9 5.2 2.2e-31 108.0 0.1 4.4 5 0 0 5 5 5 1 Multicopper oxidase ATP11 PF06644.6 EIM91880.1 - 2.1e-61 207.7 0.0 2.3e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Rtf2 PF04641.7 EIM91881.1 - 1.7e-70 237.1 4.0 2.3e-70 236.7 2.8 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EIM91881.1 - 0.00028 20.3 0.0 0.093 12.2 0.0 2.5 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EIM91881.1 - 0.017 14.8 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Med19 PF10278.4 EIM91881.1 - 0.14 11.7 6.2 0.37 10.4 3.3 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF2058 PF09831.4 EIM91881.1 - 4.9 7.0 9.1 5.8 6.7 5.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Med21 PF11221.3 EIM91882.1 - 3e-25 88.8 6.7 3.5e-25 88.6 4.6 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex ENT PF03735.9 EIM91882.1 - 0.1 12.3 0.4 0.36 10.5 0.1 2.2 2 1 0 2 2 2 0 ENT domain HalX PF08663.5 EIM91882.1 - 0.22 11.5 4.9 4.8 7.2 0.1 2.5 2 0 0 2 2 2 0 HalX domain DUF1192 PF06698.6 EIM91882.1 - 0.22 11.3 2.3 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2229 PF09989.4 EIM91882.1 - 0.24 10.8 2.2 0.32 10.4 1.5 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Enkurin PF13864.1 EIM91882.1 - 0.64 10.2 4.8 0.55 10.4 2.3 1.7 1 1 1 2 2 2 0 Calmodulin-binding PocR PF10114.4 EIM91882.1 - 0.66 9.1 4.1 4 6.5 0.2 2.2 2 1 0 2 2 2 0 Sensory domain found in PocR DUF4140 PF13600.1 EIM91882.1 - 0.96 9.9 4.7 0.92 9.9 1.2 2.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PP2C_C PF07830.8 EIM91882.1 - 8.6 6.5 7.0 1.4 9.1 1.1 2.3 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain PS_Dcarbxylase PF02666.10 EIM91883.1 - 3.2e-74 248.6 0.0 2.7e-56 190.0 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NAD_binding_10 PF13460.1 EIM91884.1 - 1.3e-15 57.9 0.1 9.2e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EIM91884.1 - 0.00065 19.0 0.0 0.0024 17.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family IPK PF03770.11 EIM91885.1 - 4.5e-42 143.9 0.0 4.3e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase CENP-B_dimeris PF09026.5 EIM91885.1 - 0.0081 16.3 6.3 0.02 15.1 4.3 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EIM91885.1 - 0.068 12.6 8.9 0.16 11.4 6.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EIM91885.1 - 0.42 8.5 2.8 0.64 7.9 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EIM91885.1 - 1 9.1 4.4 2.2 8.0 3.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 EIM91885.1 - 1.2 8.7 7.3 0.15 11.6 2.2 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EIM91885.1 - 2.5 5.8 6.7 1.4 6.6 1.4 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Aminotran_4 PF01063.14 EIM91886.1 - 2.6e-21 76.1 0.0 7.5e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV Glyco_trans_1_4 PF13692.1 EIM91886.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 YukC PF10140.4 EIM91888.1 - 0.031 12.8 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF3328 PF11807.3 EIM91889.1 - 1.1e-24 87.3 0.1 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4051 PF13260.1 EIM91890.1 - 0.19 11.1 1.3 0.55 9.6 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Methyltransf_23 PF13489.1 EIM91891.1 - 8.4e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM91891.1 - 3.3e-05 24.2 0.0 7.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM91891.1 - 5.3e-05 23.7 0.0 0.001 19.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM91891.1 - 6.7e-05 23.2 0.0 0.00059 20.2 0.0 2.5 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIM91891.1 - 0.0023 18.2 0.0 0.0061 16.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91891.1 - 0.003 17.1 0.0 0.11 12.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIM91891.1 - 0.057 12.3 0.0 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EIM91891.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAM2 PF07145.10 EIM91892.1 - 0.14 11.6 12.9 0.031 13.7 0.7 3.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DEAD PF00270.24 EIM91893.1 - 2.6e-45 153.9 0.0 6.5e-45 152.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM91893.1 - 3e-25 87.8 0.0 6.2e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM91893.1 - 4.1e-06 26.7 0.0 1.9e-05 24.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIM91893.1 - 0.00023 20.3 0.0 0.00054 19.1 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EIM91893.1 - 0.00048 18.6 0.0 0.013 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) DDHD PF02862.12 EIM91894.1 - 0.29 10.9 5.3 0.31 10.7 3.7 1.0 1 0 0 1 1 1 0 DDHD domain Cytochrom_C552 PF02335.10 EIM91894.1 - 1.1 7.9 6.4 1.2 7.7 4.4 1.0 1 0 0 1 1 1 0 Cytochrome c552 LEA_4 PF02987.11 EIM91894.1 - 2.5 8.0 21.7 0.074 12.9 9.7 2.4 2 1 0 2 2 2 0 Late embryogenesis abundant protein DUF1863 PF08937.6 EIM91895.1 - 0.058 13.4 0.0 0.079 13.0 0.0 1.3 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) IBR PF01485.16 EIM91898.1 - 1.3e-16 60.2 33.7 1.5e-10 40.8 2.5 3.9 4 0 0 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EIM91898.1 - 0.008 15.9 1.6 0.008 15.9 1.1 5.0 3 3 1 4 4 4 1 Ring finger domain Oxysterol_BP PF01237.13 EIM91899.1 - 8.9e-86 287.5 0.0 1.1e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein UPF0052 PF01933.13 EIM91900.1 - 4.4e-45 154.3 0.0 6.8e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Ras PF00071.17 EIM91902.1 - 2.2e-64 215.7 0.0 2.6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM91902.1 - 8.7e-20 71.3 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM91902.1 - 1.2e-14 53.8 0.1 1.6e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIM91902.1 - 7.5e-06 25.2 0.0 9.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIM91902.1 - 8.7e-06 25.2 0.1 2.2e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM91902.1 - 0.00029 20.7 0.0 0.00058 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM91902.1 - 0.0077 15.5 0.0 0.39 9.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 EIM91902.1 - 0.03 14.2 0.1 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EIM91902.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EIM91902.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EIM91902.1 - 0.058 12.6 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EIM91902.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EIM91902.1 - 0.079 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EIM91902.1 - 0.08 13.1 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EIM91902.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin UvrD_C PF13361.1 EIM91903.1 - 1.5e-08 34.5 0.0 3.9e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 EIM91903.1 - 5.3e-05 23.3 0.2 0.0038 17.3 0.1 2.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain TPR_1 PF00515.23 EIM91903.1 - 0.0089 15.5 6.6 0.44 10.2 0.2 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 EIM91903.1 - 0.016 15.3 1.6 2.2 8.4 0.0 3.9 3 1 0 3 3 3 0 AAA domain UvrD-helicase PF00580.16 EIM91903.1 - 0.022 14.0 0.1 1.3 8.2 0.1 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TPR_2 PF07719.12 EIM91903.1 - 0.025 14.4 10.4 0.23 11.4 0.5 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91903.1 - 0.047 13.3 6.1 0.71 9.5 0.2 3.2 3 0 0 3 3 3 0 TPR repeat HBS1_N PF08938.5 EIM91903.1 - 0.056 13.5 0.2 0.6 10.2 0.1 2.6 2 0 0 2 2 2 0 HBS1 N-terminus TPR_8 PF13181.1 EIM91903.1 - 0.086 12.6 1.3 2 8.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF87 PF01935.12 EIM91903.1 - 0.28 10.9 0.8 45 3.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 TPR_12 PF13424.1 EIM91903.1 - 2 8.3 10.1 0.41 10.6 0.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1547 PF07577.6 EIM91904.1 - 0.012 15.2 0.1 0.082 12.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Actin PF00022.14 EIM91906.1 - 1.8e-44 151.7 0.0 2.2e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Actin UvrD_C PF13361.1 EIM91907.1 - 1.1e-12 48.1 0.0 3.1e-10 40.0 0.0 3.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EIM91907.1 - 7.2e-06 25.5 5.1 1.5e-05 24.5 0.0 2.9 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EIM91907.1 - 3.9e-05 23.7 0.1 0.0023 18.0 0.0 2.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EIM91907.1 - 0.0013 18.8 0.5 0.095 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EIM91907.1 - 0.0015 17.9 0.1 0.0066 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 EIM91907.1 - 0.0021 17.8 5.2 1.1 9.3 0.0 4.6 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIM91907.1 - 0.078 12.8 2.9 17 5.5 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_19 PF13245.1 EIM91907.1 - 0.18 11.5 0.0 0.84 9.4 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain TPR_1 PF00515.23 EIM91907.1 - 0.33 10.6 2.7 28 4.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91907.1 - 0.58 9.8 9.0 1.4 8.6 0.5 4.1 5 0 0 5 5 5 0 TPR repeat ABC_tran PF00005.22 EIM91908.1 - 5.9e-27 94.6 0.0 2.3e-26 92.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIM91908.1 - 5.2e-13 49.6 0.1 4.9e-11 43.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIM91908.1 - 3.9e-10 39.3 0.0 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EIM91908.1 - 2.1e-07 30.4 0.0 3.1e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIM91908.1 - 0.00024 21.4 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIM91908.1 - 0.00059 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EIM91908.1 - 0.00068 20.4 0.0 0.0017 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM91908.1 - 0.0089 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EIM91908.1 - 0.0098 15.3 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 EIM91908.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIM91908.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIM91908.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EIM91908.1 - 0.023 14.7 0.1 0.059 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EIM91908.1 - 0.045 12.4 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.1 EIM91908.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EIM91908.1 - 0.063 11.7 0.0 0.12 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIM91908.1 - 0.088 12.9 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM91908.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 EIM91908.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EIM91908.1 - 0.16 11.4 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Nic96 PF04097.9 EIM91909.1 - 6.1e-123 411.0 0.0 8.1e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF4047 PF13256.1 EIM91909.1 - 1.6 8.6 3.6 22 5.0 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4047) Filament PF00038.16 EIM91910.1 - 0.0046 16.4 2.1 0.0069 15.8 1.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein MAD PF05557.8 EIM91910.1 - 0.012 13.6 3.5 0.016 13.2 2.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4159 PF13709.1 EIM91910.1 - 0.022 13.9 0.1 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) FH2 PF02181.18 EIM91910.1 - 0.03 13.1 0.9 0.049 12.5 0.6 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF3080 PF11279.3 EIM91910.1 - 0.037 13.1 1.6 0.056 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) APH PF01636.18 EIM91911.1 - 6.6e-18 65.3 0.0 4.9e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIM91911.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIM91911.1 - 0.069 12.4 0.1 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EIM91911.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UbiA PF01040.13 EIM91912.1 - 0.0062 15.7 2.6 0.016 14.4 1.8 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family DNA_topoisoIV PF00521.15 EIM91914.1 - 6.5e-128 427.2 0.3 1.1e-127 426.4 0.2 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EIM91914.1 - 2.1e-34 118.2 1.9 4.8e-34 117.0 1.3 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EIM91914.1 - 1.6e-15 56.9 0.0 9.1e-15 54.4 0.0 2.4 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EIM91914.1 - 8.5e-08 31.8 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HNH_2 PF13391.1 EIM91915.1 - 2.5e-09 36.7 0.0 4.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Glypican PF01153.14 EIM91916.1 - 0.85 8.1 4.8 0.83 8.1 3.3 1.1 1 0 0 1 1 1 0 Glypican HNH_2 PF13391.1 EIM91917.1 - 8.6e-11 41.4 0.6 2.5e-10 39.9 0.4 1.8 1 1 0 1 1 1 1 HNH endonuclease Rubella_Capsid PF05750.6 EIM91917.1 - 0.14 11.5 1.6 0.22 10.8 1.1 1.2 1 0 0 1 1 1 0 Rubella capsid protein ABC_tran PF00005.22 EIM91918.1 - 4.1e-45 153.4 0.6 9.4e-22 77.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EIM91918.1 - 2.8e-22 78.3 5.5 2.8e-22 78.3 3.8 2.9 2 1 1 3 3 1 1 ABC transporter AAA_21 PF13304.1 EIM91918.1 - 5.8e-17 62.5 7.2 0.0013 18.7 0.1 4.8 3 2 0 4 4 3 3 AAA domain SMC_N PF02463.14 EIM91918.1 - 2.1e-08 33.7 1.7 0.022 14.0 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIM91918.1 - 1.1e-07 32.6 1.7 0.017 15.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EIM91918.1 - 1.4e-07 30.8 0.1 0.0089 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIM91918.1 - 2.3e-07 30.7 0.0 0.0078 16.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIM91918.1 - 5.7e-07 30.0 0.0 0.069 13.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 EIM91918.1 - 7.8e-07 28.1 0.1 0.00055 18.7 0.0 2.5 2 0 0 2 2 2 2 ArgK protein DUF258 PF03193.11 EIM91918.1 - 2.2e-06 26.9 0.1 0.038 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EIM91918.1 - 2.5e-06 27.5 0.0 0.066 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIM91918.1 - 1.5e-05 25.1 1.1 0.086 12.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 EIM91918.1 - 2.3e-05 24.1 0.1 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EIM91918.1 - 6.1e-05 22.7 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIM91918.1 - 0.00012 21.6 0.0 0.23 10.8 0.1 2.7 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EIM91918.1 - 0.00028 21.1 7.1 0.42 10.9 0.0 4.8 5 1 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EIM91918.1 - 0.00056 19.3 0.0 0.24 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIM91918.1 - 0.0018 18.6 18.7 0.015 15.5 0.0 4.7 5 0 0 5 5 5 1 AAA domain AAA_14 PF13173.1 EIM91918.1 - 0.0021 17.9 0.1 3.9 7.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIM91918.1 - 0.0026 17.7 8.2 0.51 10.2 0.1 3.4 3 2 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.18 EIM91918.1 - 0.0028 17.5 5.2 0.28 10.9 0.1 3.4 4 1 0 4 4 3 2 Dynamin family RNA_helicase PF00910.17 EIM91918.1 - 0.003 17.7 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EIM91918.1 - 0.0034 17.2 0.3 1.3 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EIM91918.1 - 0.009 15.9 0.8 0.76 9.7 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 EIM91918.1 - 0.01 14.8 0.1 0.44 9.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA PF00004.24 EIM91918.1 - 0.015 15.5 0.0 7.7 6.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EIM91918.1 - 0.016 14.9 0.1 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 EIM91918.1 - 0.032 14.0 0.0 0.032 14.0 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function DUF87 cobW PF02492.14 EIM91918.1 - 0.032 13.6 0.1 9.3 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GBP_repeat PF02526.9 EIM91918.1 - 0.036 13.4 0.2 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycophorin-binding protein ATP-synt_ab PF00006.20 EIM91918.1 - 0.042 13.3 0.3 5.1 6.5 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EIM91918.1 - 0.046 13.2 0.0 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FlxA PF14282.1 EIM91918.1 - 0.056 13.3 5.2 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 FlxA-like protein AAA_5 PF07728.9 EIM91918.1 - 0.057 13.1 0.5 5 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EIM91918.1 - 0.061 12.3 14.2 0.26 10.2 0.1 4.6 4 2 1 5 5 5 0 AAA ATPase domain MutS_V PF00488.16 EIM91918.1 - 0.069 12.5 0.0 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 MutS domain V Arch_ATPase PF01637.13 EIM91918.1 - 0.12 12.0 2.5 3.3 7.3 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EIM91918.1 - 5.3 6.4 7.8 1.7 8.1 0.0 3.1 4 0 0 4 4 3 0 FtsK/SpoIIIE family DOT1 PF08123.8 EIM91919.1 - 1.6e-60 203.9 0.0 1.9e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EIM91919.1 - 4e-05 24.1 0.0 7.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM91919.1 - 8.9e-05 22.4 0.0 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM91919.1 - 0.026 14.0 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EIM91919.1 - 0.046 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 2OG-FeII_Oxy PF03171.15 EIM91920.1 - 2e-06 28.0 0.0 6.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EIM91920.1 - 5.4e-05 23.6 0.1 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrolase_like PF13242.1 EIM91921.1 - 0.099 12.3 0.9 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Cytochrom_B_N PF00033.14 EIM91922.1 - 0.074 12.4 4.4 0.11 11.8 3.0 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB UPF0114 PF03350.11 EIM91922.1 - 0.9 9.4 10.0 0.12 12.2 2.6 2.3 1 1 1 2 2 2 0 Uncharacterized protein family, UPF0114 F-box-like PF12937.2 EIM91923.1 - 3.4e-06 26.6 0.1 8.4e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91923.1 - 4.3e-05 23.0 0.2 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 1 F-box domain Malate_DH PF12434.3 EIM91924.1 - 0.3 10.8 0.1 0.3 10.8 0.0 2.3 3 0 0 3 3 3 0 Malate dehydrogenase enzyme DNA_methylase PF00145.12 EIM91925.1 - 8.7e-29 100.6 0.0 3.3e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase eIF-5_eIF-2B PF01873.12 EIM91926.1 - 2.4e-42 143.5 0.0 3.7e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EIM91926.1 - 3.3e-27 94.2 1.6 5.9e-27 93.4 0.3 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Thiolase_N PF00108.18 EIM91927.1 - 2.9e-09 36.2 0.0 2.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIM91927.1 - 1.8e-06 27.3 0.0 1.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIM91927.1 - 0.00011 21.7 2.1 0.14 11.6 0.1 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIM91927.1 - 0.00022 20.7 0.2 0.035 13.7 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4238 PF14022.1 EIM91928.1 - 2.3e-09 36.9 0.0 7.5e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) DUF1120 PF06551.7 EIM91928.1 - 0.2 11.9 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Pox_G5 PF04599.7 EIM91928.1 - 0.24 10.0 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF4238 PF14022.1 EIM91929.1 - 7.5e-08 31.9 0.0 2.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.18 EIM91931.1 - 0.0004 20.2 0.1 0.0017 18.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM91931.1 - 0.06 12.3 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EIM91932.1 - 1.9e-06 27.5 0.0 7.8e-06 25.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91932.1 - 0.0001 21.8 2.8 0.00012 21.6 0.0 2.7 3 0 0 3 3 3 1 F-box domain Zn_Tnp_IS91 PF14319.1 EIM91932.1 - 0.027 13.9 0.2 0.027 13.9 0.1 2.4 3 0 0 3 3 3 0 Transposase zinc-binding domain PHD PF00628.24 EIM91933.1 - 4.1e-11 42.3 8.2 6.7e-11 41.7 5.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIM91933.1 - 3.3e-06 26.3 5.8 5.7e-06 25.5 4.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EIM91933.1 - 0.047 13.4 4.4 0.11 12.2 3.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EIM91933.1 - 0.049 12.9 1.3 0.11 11.8 0.9 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-CW PF07496.10 EIM91933.1 - 0.26 10.9 3.5 0.51 10.0 2.4 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.17 EIM91933.1 - 3.8 7.3 6.5 0.65 9.7 1.8 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HATPase_c_3 PF13589.1 EIM91935.1 - 6.2e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 EIM91935.1 - 0.004 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) F-box PF00646.28 EIM91936.1 - 5.8e-05 22.6 2.9 5.8e-05 22.6 2.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EIM91936.1 - 0.0022 17.6 0.3 0.0072 16.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Alpha_L_fucos PF01120.12 EIM91936.1 - 0.089 11.6 0.4 0.13 11.1 0.3 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase DUF3883 PF13020.1 EIM91937.1 - 0.00016 21.3 0.0 0.00081 19.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) FYVE PF01363.16 EIM91939.1 - 8.4e-19 67.2 3.9 1.5e-18 66.4 2.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EIM91939.1 - 0.039 13.8 2.7 0.087 12.7 1.9 1.6 1 0 0 1 1 1 0 IBR domain Transposase_21 PF02992.9 EIM91940.1 - 3.6e-12 45.8 0.0 1.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIM91940.1 - 0.0057 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2365 PF10157.4 EIM91940.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF3947 PF13135.1 EIM91940.1 - 0.28 11.4 4.5 2.6 8.3 3.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3947) Imm44 PF15584.1 EIM91941.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 44 F-box PF00646.28 EIM91944.1 - 7.6e-05 22.2 5.7 7.8e-05 22.2 1.5 3.0 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM91944.1 - 0.00081 19.0 0.3 0.0027 17.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like Bestrophin PF01062.16 EIM91945.1 - 1.3e-43 149.0 0.1 2.7e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DAP PF15228.1 EIM91946.1 - 4.9 7.9 7.7 0.25 12.1 0.8 2.2 3 0 0 3 3 3 0 Death-associated protein CHAT PF12770.2 EIM91947.1 - 5.3e-22 78.2 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EIM91947.1 - 1.2e-08 34.7 1.4 0.00088 19.1 0.1 4.7 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIM91947.1 - 0.00026 20.5 0.1 2.2 7.9 0.0 4.2 3 2 2 5 5 5 3 TPR repeat TPR_10 PF13374.1 EIM91947.1 - 0.00049 19.9 5.0 0.65 10.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIM91947.1 - 0.033 14.0 0.6 54 4.0 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Bestrophin PF01062.16 EIM91948.1 - 5.3e-16 58.4 0.7 7.7e-16 57.8 0.1 1.4 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel Macoilin PF09726.4 EIM91948.1 - 5.5 5.1 6.3 8 4.6 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SET PF00856.23 EIM91949.1 - 5.3e-14 52.8 0.0 4.9e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 EIM91949.1 - 3.5e-10 39.3 0.0 4.2e-09 35.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat adh_short_C2 PF13561.1 EIM91950.1 - 1e-26 94.2 0.0 1.3e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM91950.1 - 1.2e-26 93.5 1.2 1.2e-26 93.5 0.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIM91950.1 - 8.4e-15 54.8 0.4 1.4e-14 54.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIM91950.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIM91950.1 - 0.13 11.6 0.1 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HA2 PF04408.18 EIM91951.1 - 4.3e-28 97.3 0.0 1.8e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM91951.1 - 1e-23 83.3 0.0 2.8e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM91951.1 - 7.7e-11 41.7 0.5 2.4e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain F-box PF00646.28 EIM91953.1 - 1.1e-06 28.0 4.0 5.1e-06 25.9 1.5 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIM91953.1 - 1e-05 25.1 0.2 3.2e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Flavodoxin_5 PF12724.2 EIM91953.1 - 0.21 11.6 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain LSM PF01423.17 EIM91954.1 - 6.6e-06 25.5 0.0 7.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol3_beta_2 PF02767.11 EIM91954.1 - 0.0096 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III beta subunit, central domain DUF4444 PF14563.1 EIM91954.1 - 0.022 14.1 1.6 0.039 13.3 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4444) NADH_4Fe-4S PF10589.4 EIM91955.1 - 0.059 12.5 0.1 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Glycos_transf_2 PF00535.21 EIM91956.1 - 2.9e-31 108.4 0.0 3.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIM91956.1 - 9e-15 55.0 0.0 1.3e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EIM91956.1 - 8.8e-08 31.5 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 F-box-like PF12937.2 EIM91957.1 - 3.9e-07 29.6 0.0 6.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM91957.1 - 5.9e-05 22.6 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EIM91957.1 - 0.2 12.0 1.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sel1 PF08238.7 EIM91958.1 - 4.8e-20 71.5 10.8 5.3e-07 30.0 0.0 3.3 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.1 EIM91958.1 - 0.0085 16.7 1.5 0.093 13.4 0.3 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat PBP PF01161.15 EIM91959.1 - 5.5e-18 65.2 0.8 1e-17 64.3 0.6 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein AAA_10 PF12846.2 EIM91961.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain BTB PF00651.26 EIM91962.1 - 4.3e-07 29.8 0.1 8.9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BUD22 PF09073.5 EIM91963.1 - 0.0059 15.7 10.8 0.0059 15.7 7.5 1.6 2 0 0 2 2 2 1 BUD22 MerR PF00376.18 EIM91965.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 MerR family regulatory protein DUF3783 PF12646.2 EIM91965.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) FTHFS PF01268.14 EIM91967.1 - 1.8e-34 118.6 1.4 2.4e-34 118.2 1.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase DnaI_N PF07319.6 EIM91968.1 - 0.003 17.7 0.3 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 Primosomal protein DnaI N-terminus BUD22 PF09073.5 EIM91969.1 - 2.4 7.1 17.7 3.7 6.5 12.3 1.2 1 0 0 1 1 1 0 BUD22 Taeniidae_ag PF05596.6 EIM91972.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Taeniidae antigen DUF4413 PF14372.1 EIM91973.1 - 0.06 13.3 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 EIM91974.1 - 1.4e-13 50.2 0.1 1.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0147 PF03685.8 EIM91975.1 - 0.062 13.1 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) zf-BED PF02892.10 EIM91976.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger Asp_protease_2 PF13650.1 EIM91979.1 - 3e-05 24.4 0.0 3.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.3 EIM91979.1 - 0.00015 21.5 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase RVP_2 PF08284.6 EIM91979.1 - 0.00022 21.1 0.0 0.00024 21.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIM91979.1 - 0.0028 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIM91980.1 - 0.2 11.7 2.1 0.69 10.0 1.4 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein Spindle_Spc25 PF08234.7 EIM91982.1 - 4.5e-06 26.5 0.0 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4200 PF13863.1 EIM91982.1 - 0.00046 20.1 7.0 0.00077 19.4 4.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Cast PF10174.4 EIM91982.1 - 0.00078 17.6 2.9 0.00092 17.3 2.0 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 EIM91982.1 - 0.0015 18.1 2.8 0.0016 17.9 1.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 EIM91982.1 - 0.0016 16.9 5.1 0.0021 16.6 3.5 1.0 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 EIM91982.1 - 0.0029 16.8 1.4 0.0038 16.4 1.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 EIM91982.1 - 0.011 14.3 4.4 0.015 14.0 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein THOC7 PF05615.8 EIM91982.1 - 0.023 14.9 5.9 0.041 14.1 4.1 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 IFT57 PF10498.4 EIM91982.1 - 0.029 13.1 3.7 0.039 12.6 2.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 EIM91982.1 - 0.031 14.1 8.5 0.053 13.3 5.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Paramyx_P_V_C PF03210.8 EIM91982.1 - 0.032 14.1 1.6 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal AAA_27 PF13514.1 EIM91982.1 - 0.035 11.7 6.9 0.045 11.4 4.8 1.0 1 0 0 1 1 1 0 AAA domain DUF2353 PF09789.4 EIM91982.1 - 0.036 13.3 6.6 0.017 14.3 3.1 1.5 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Mnd1 PF03962.10 EIM91982.1 - 0.046 13.3 4.8 0.058 13.0 3.3 1.3 1 0 0 1 1 1 0 Mnd1 family Rootletin PF15035.1 EIM91982.1 - 0.051 13.5 7.6 0.068 13.1 5.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RE_Alw26IDE PF09665.5 EIM91982.1 - 0.073 11.7 2.7 0.093 11.4 1.9 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF972 PF06156.8 EIM91982.1 - 0.076 13.3 5.9 0.45 10.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIM91982.1 - 0.12 12.0 6.6 0.24 10.9 4.5 1.4 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 EIM91982.1 - 0.12 10.7 4.0 0.15 10.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 EIM91982.1 - 0.16 11.8 2.4 4.7 7.1 1.7 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EIM91982.1 - 0.17 11.6 3.1 0.69 9.7 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EIM91982.1 - 0.17 10.7 5.9 0.25 10.2 4.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EIM91982.1 - 0.27 10.7 6.0 0.45 10.0 3.6 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EIM91982.1 - 0.32 11.4 6.9 0.15 12.5 1.4 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EIM91982.1 - 0.38 9.7 7.8 0.58 9.1 5.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Bcr-Abl_Oligo PF09036.5 EIM91982.1 - 0.48 10.4 3.2 0.94 9.4 0.5 2.5 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DivIC PF04977.10 EIM91982.1 - 0.86 9.1 4.8 0.4 10.1 0.3 2.3 2 1 0 2 2 2 0 Septum formation initiator Nup54 PF13874.1 EIM91982.1 - 0.88 9.2 6.7 1.3 8.6 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YgaB PF14182.1 EIM91982.1 - 1.1 9.5 5.2 6.6 7.0 1.9 2.3 1 1 1 2 2 2 0 YgaB-like protein TMF_TATA_bd PF12325.3 EIM91982.1 - 1.3 8.7 8.0 2.1 8.0 3.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HAUS6_N PF14661.1 EIM91982.1 - 8.3 5.6 8.2 21 4.3 5.7 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase PF00069.20 EIM91983.1 - 1.8e-57 194.4 0.0 4.7e-57 193.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM91983.1 - 4.6e-29 101.2 0.1 1.7e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM91983.1 - 5.4e-05 22.2 0.4 0.0025 16.8 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EIM91983.1 - 0.0069 16.1 0.2 0.078 12.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIM91983.1 - 0.0082 15.2 0.2 0.068 12.2 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIM91983.1 - 0.075 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MFS_1 PF07690.11 EIM91984.1 - 7.4e-14 51.2 32.6 7.4e-14 51.2 22.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIM91984.1 - 7.1e-11 41.8 6.0 7.1e-11 41.8 4.2 2.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 TB2_DP1_HVA22 PF03134.14 EIM91985.1 - 9.4e-28 95.8 5.4 1.5e-27 95.1 3.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TFIIS_C PF01096.13 EIM91986.1 - 1.7e-16 59.5 0.9 1.7e-16 59.5 0.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIM91986.1 - 2e-08 33.7 5.8 6.9e-08 32.0 0.2 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF2387 PF09526.5 EIM91986.1 - 6.7e-05 22.7 6.0 0.027 14.3 0.4 2.4 2 1 0 2 2 2 2 Probable metal-binding protein (DUF2387) DZR PF12773.2 EIM91986.1 - 0.00011 21.9 7.7 0.0013 18.4 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon Baculo_LEF5_C PF11792.3 EIM91986.1 - 0.00016 21.0 0.9 0.00016 21.0 0.6 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain DUF2082 PF09855.4 EIM91986.1 - 0.019 14.8 4.5 1.8 8.4 1.1 2.9 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EIM91986.1 - 0.019 14.6 6.9 0.19 11.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 EIM91986.1 - 0.02 14.6 10.2 0.028 14.2 0.7 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIM91986.1 - 0.022 14.6 8.8 3.1 7.8 0.1 3.5 3 1 1 4 4 4 0 Zinc ribbon domain Mu-like_Com PF10122.4 EIM91986.1 - 0.023 13.7 0.4 1.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Elf1 PF05129.8 EIM91986.1 - 0.03 14.0 7.8 0.087 12.5 0.7 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DNA_RNApol_7kD PF03604.8 EIM91986.1 - 0.035 13.5 11.3 0.06 12.8 1.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit IBR PF01485.16 EIM91986.1 - 0.063 13.1 8.7 0.3 10.9 0.2 2.5 2 1 0 2 2 2 0 IBR domain Terminase_GpA PF05876.7 EIM91986.1 - 0.081 11.2 4.5 0.26 9.5 0.8 2.0 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_2 PF13240.1 EIM91986.1 - 0.095 12.2 12.6 4.1 7.0 0.6 3.3 2 1 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EIM91986.1 - 0.1 12.9 6.9 2.5 8.4 0.1 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar CpXC PF14353.1 EIM91986.1 - 0.13 12.1 6.4 5.6 6.9 0.1 3.0 1 1 1 3 3 2 0 CpXC protein PHD PF00628.24 EIM91986.1 - 0.14 11.8 9.7 0.44 10.2 0.4 2.9 2 1 1 3 3 3 0 PHD-finger TF_Zn_Ribbon PF08271.7 EIM91986.1 - 0.18 11.1 13.1 1 8.7 0.3 3.8 3 1 0 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EIM91986.1 - 0.21 10.8 16.4 1.2 8.4 0.1 3.7 3 1 2 5 5 5 0 zinc-ribbon domain zf-CHY PF05495.7 EIM91986.1 - 0.24 11.6 6.8 0.89 9.7 0.1 2.8 2 1 0 2 2 2 0 CHY zinc finger HypA PF01155.14 EIM91986.1 - 0.29 10.8 7.4 0.4 10.3 0.2 2.5 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EIM91986.1 - 0.36 10.5 8.2 0.74 9.5 0.3 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.1 EIM91986.1 - 0.57 9.8 11.2 12 5.5 1.0 3.8 3 1 1 4 4 4 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 EIM91986.1 - 0.68 9.2 4.9 0.59 9.4 0.8 2.1 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Cytochrome_C554 PF13435.1 EIM91986.1 - 0.9 9.6 6.8 2.3 8.2 4.8 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Zn_ribbon_recom PF13408.1 EIM91986.1 - 0.95 9.7 8.7 21 5.4 0.1 3.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Stc1 PF12898.2 EIM91986.1 - 1.1 9.3 6.8 1.1 9.3 3.7 1.8 1 1 0 1 1 1 0 Stc1 domain zf-NADH-PPase PF09297.6 EIM91986.1 - 1.4 8.4 12.5 15 5.1 4.4 3.2 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cytochrom_CIII PF02085.11 EIM91986.1 - 2.2 8.4 8.8 4.5 7.4 5.4 2.0 1 1 1 2 2 2 0 Class III cytochrome C family A2L_zn_ribbon PF08792.5 EIM91986.1 - 3 7.3 12.6 5.5 6.5 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF164 PF02591.10 EIM91986.1 - 3.4 7.5 6.4 22 4.9 0.5 3.3 3 1 1 4 4 3 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 EIM91986.1 - 4.5 7.0 11.9 26 4.6 0.2 3.8 3 1 1 4 4 4 0 zinc-ribbon domain DUF4379 PF14311.1 EIM91986.1 - 4.7 7.1 10.4 12 5.7 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4379) DUF1451 PF07295.6 EIM91986.1 - 4.9 6.9 9.4 1.4 8.6 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) DUF983 PF06170.7 EIM91986.1 - 6.2 7.0 8.8 0.4 10.8 0.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF983) Rpr2 PF04032.11 EIM91986.1 - 9.3 6.2 9.6 8 6.4 0.7 3.2 2 2 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MutS_V PF00488.16 EIM91989.1 - 1.1e-70 237.7 0.0 2e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIM91989.1 - 4.2e-28 98.5 0.6 4.2e-28 98.5 0.4 1.6 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EIM91989.1 - 1.1e-06 28.6 0.0 5.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EIM91989.1 - 2.2e-06 27.7 0.0 5.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Candida_ALS PF05792.8 EIM91989.1 - 0.21 11.7 1.4 0.44 10.7 1.0 1.4 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) ArfGap PF01412.13 EIM91990.1 - 1.6e-42 143.9 0.3 2.6e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GET2 PF08690.5 EIM91991.1 - 1.7 7.8 9.5 0.21 10.7 0.6 2.9 2 1 0 2 2 2 0 GET complex subunit GET2 DUF1517 PF07466.6 EIM91991.1 - 5.1 6.0 5.8 9.4 5.1 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) L51_S25_CI-B8 PF05047.11 EIM91992.1 - 4.4e-09 35.9 0.2 7.2e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain YL1 PF05764.8 EIM91993.1 - 3.7e-30 105.2 20.2 4.5e-30 105.0 14.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SRP-alpha_N PF04086.8 EIM91993.1 - 0.03 13.7 16.1 0.049 13.0 11.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_M1 PF01433.15 EIM91994.1 - 7.2e-59 199.8 0.0 9.8e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIM91994.1 - 3.2e-28 98.1 0.2 3.5e-27 94.7 0.1 2.4 1 1 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIM91994.1 - 3.3e-15 56.2 0.5 7.8e-15 55.0 0.1 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EIM91994.1 - 0.54 10.2 3.3 8.1 6.4 2.3 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Nup160 PF11715.3 EIM91995.1 - 7.5e-37 126.6 0.0 1.1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_S15 PF00312.17 EIM91995.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S15 SET PF00856.23 EIM91996.1 - 1.8e-11 44.6 0.0 5.8e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 SET domain adh_short PF00106.20 EIM91997.1 - 5.9e-14 52.3 0.0 9.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM91997.1 - 2.2e-08 34.0 0.1 3.8e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIM91997.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EIM91997.1 - 0.075 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EIM91997.1 - 0.14 11.5 0.3 0.74 9.2 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HEAT_2 PF13646.1 EIM91998.1 - 2.8e-09 37.1 13.6 0.0094 16.2 0.1 7.3 5 1 1 6 6 6 4 HEAT repeats Adaptin_N PF01602.15 EIM91998.1 - 4.9e-07 28.4 1.1 7.6e-06 24.5 0.0 2.9 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.17 EIM91998.1 - 1.2e-05 24.9 7.3 4.8 7.5 0.0 9.1 10 0 0 10 10 10 1 HEAT repeat DUF2435 PF10363.4 EIM91998.1 - 0.043 13.7 0.5 4.6 7.2 0.0 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) DUF3619 PF12279.3 EIM91998.1 - 0.17 11.9 7.1 0.45 10.6 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) HEAT_EZ PF13513.1 EIM91998.1 - 0.29 11.6 18.5 8.6 7.0 0.1 8.6 8 3 2 10 10 10 0 HEAT-like repeat Syja_N PF02383.13 EIM91999.1 - 2.5e-88 295.9 0.0 3.8e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain APH PF01636.18 EIM92000.1 - 5.3e-08 32.8 0.1 6.2e-05 22.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIM92000.1 - 4e-07 29.4 0.0 6.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EIM92000.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Oxidored-like PF09791.4 EIM92001.1 - 3.2e-16 58.4 0.3 6e-16 57.6 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DAO PF01266.19 EIM92002.1 - 2.3e-28 99.1 0.0 7.8e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM92002.1 - 0.026 14.5 0.0 0.083 12.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIM92002.1 - 0.083 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM92002.1 - 0.13 12.3 0.0 4.3 7.3 0.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EIM92002.1 - 0.16 11.6 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 EIM92004.1 - 3.9e-63 213.5 0.0 6.9e-63 212.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM92005.1 - 3e-39 134.8 0.0 5.2e-39 134.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EIM92006.1 - 5.6e-15 55.4 0.4 7.5e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM92006.1 - 1.9e-10 40.0 0.2 4.7e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIM92006.1 - 1.5e-07 31.2 0.4 2.1e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EIM92006.1 - 2.2e-06 26.5 0.0 2.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EIM92006.1 - 4.3e-06 26.7 2.5 5.8e-06 26.3 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIM92006.1 - 0.0042 16.3 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EIM92006.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein p450 PF00067.17 EIM92007.1 - 2.6e-38 131.7 0.0 2.1e-37 128.7 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 zf-C2H2_4 PF13894.1 EIM92008.1 - 0.01 16.1 4.1 1.4 9.4 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Vps35 PF03635.12 EIM92009.1 - 0 1042.6 0.1 0 1042.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.16 EIM92009.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease L-PSP VHS PF00790.14 EIM92010.1 - 6.7e-43 145.7 0.1 2.9e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EIM92010.1 - 2.7e-16 59.2 6.3 4.5e-16 58.5 4.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EIM92010.1 - 0.00087 18.6 13.4 0.05 13.1 2.0 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EIM92010.1 - 0.0015 18.4 3.4 0.003 17.4 2.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.2 EIM92010.1 - 0.43 10.4 6.7 18 5.2 4.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF1924 PF09086.6 EIM92010.1 - 0.68 10.0 3.8 0.81 9.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) RNA_pol_Rpb1_1 PF04997.7 EIM92011.1 - 1.5e-115 386.0 0.0 2.3e-115 385.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EIM92011.1 - 3.2e-107 357.9 0.0 5.2e-107 357.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 EIM92011.1 - 7.7e-69 231.1 0.0 1.7e-68 230.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 EIM92011.1 - 8.2e-69 230.7 0.1 1.9e-68 229.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIM92011.1 - 3.9e-51 172.9 0.1 2.1e-50 170.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EIM92011.1 - 4.3e-46 155.9 1.3 1.1e-45 154.6 0.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EIM92011.1 - 1.6e-36 124.2 0.0 3.5e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ABC_sub_bind PF04392.7 EIM92011.1 - 0.14 11.0 0.2 0.55 9.1 0.1 1.8 2 0 0 2 2 2 0 ABC transporter substrate binding protein RNA_pol_Rpb1_R PF05001.8 EIM92011.1 - 0.32 11.2 120.5 0.077 13.1 7.2 9.9 2 2 9 11 11 11 0 RNA polymerase Rpb1 C-terminal repeat TIP120 PF08623.5 EIM92013.1 - 4.6e-50 169.4 0.2 3.1e-49 166.8 0.1 2.6 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EIM92013.1 - 1.8e-21 76.2 13.9 0.0022 18.2 0.1 8.9 9 1 1 10 10 8 5 HEAT repeats HEAT PF02985.17 EIM92013.1 - 3.1e-15 54.8 18.1 0.014 15.4 0.0 13.6 15 0 0 15 15 13 2 HEAT repeat HEAT_EZ PF13513.1 EIM92013.1 - 6.1e-15 55.2 19.7 0.0017 18.8 0.2 12.4 13 1 1 14 14 13 3 HEAT-like repeat CLASP_N PF12348.3 EIM92013.1 - 2.3e-12 46.7 0.9 2.6e-05 23.6 0.0 4.8 5 0 0 5 5 5 3 CLASP N terminal Adaptin_N PF01602.15 EIM92013.1 - 1.3e-09 37.0 0.1 0.065 11.5 0.0 6.0 4 2 1 5 5 5 3 Adaptin N terminal region Cnd1 PF12717.2 EIM92013.1 - 7.8e-09 35.6 0.3 2.2 8.0 0.0 6.6 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIM92013.1 - 1.4e-06 28.6 0.1 29 5.1 0.0 7.3 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EIM92013.1 - 4.8e-05 23.3 0.8 0.25 11.2 0.0 4.9 5 0 0 5 5 5 1 Parkin co-regulated protein MMS19_C PF12460.3 EIM92013.1 - 8.3e-05 21.4 13.8 0.17 10.6 0.1 5.4 5 2 0 5 5 5 2 RNAPII transcription regulator C-terminal UME PF08064.8 EIM92013.1 - 0.00011 22.1 1.1 7.6 6.5 0.0 5.4 6 2 1 7 7 5 0 UME (NUC010) domain Ipi1_N PF12333.3 EIM92013.1 - 0.00036 20.4 4.8 4.4 7.3 0.0 6.6 7 1 0 8 8 7 1 Rix1 complex component involved in 60S ribosome maturation DUF3385 PF11865.3 EIM92013.1 - 0.00058 19.8 1.4 0.017 15.0 0.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) DUF2454 PF10521.4 EIM92013.1 - 0.0015 17.6 4.1 0.89 8.5 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) V-ATPase_H_C PF11698.3 EIM92013.1 - 0.029 14.3 0.8 1.4 8.8 0.1 3.8 4 0 0 4 4 4 0 V-ATPase subunit H DUF1546 PF07571.8 EIM92013.1 - 0.05 13.7 0.6 5.1 7.2 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) Nop14 PF04147.7 EIM92013.1 - 0.27 9.0 1.5 0.53 8.1 1.0 1.5 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EIM92013.1 - 0.29 10.6 6.1 0.66 9.4 4.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Arm PF00514.18 EIM92013.1 - 0.86 9.5 7.1 22 5.0 0.0 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF2457 PF10446.4 EIM92013.1 - 8.7 4.9 12.3 16 4.0 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pro_dh PF01619.13 EIM92014.1 - 5.4e-33 114.2 0.0 1.7e-16 60.0 0.0 3.4 2 2 0 2 2 2 2 Proline dehydrogenase BCIP PF13862.1 EIM92015.1 - 2.8e-61 206.4 0.0 3.7e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Myb_Cef PF11831.3 EIM92017.1 - 2.3e-65 220.0 1.1 2.3e-65 220.0 0.8 4.4 5 1 1 6 6 6 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EIM92017.1 - 2.3e-22 78.7 6.6 8.3e-11 41.7 0.4 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM92017.1 - 3.9e-19 68.5 8.5 9e-13 48.1 2.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Trypan_PARP PF05887.6 EIM92018.1 - 1.7 8.4 5.9 2.3 8.0 4.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SET PF00856.23 EIM92019.1 - 7.4e-12 45.8 0.0 8.4e-11 42.4 0.0 2.6 1 1 0 1 1 1 1 SET domain Med9 PF07544.8 EIM92020.1 - 0.00016 21.3 0.7 0.00023 20.8 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 PilJ PF13675.1 EIM92020.1 - 0.068 13.4 0.8 0.08 13.2 0.6 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ECM11 PF15463.1 EIM92020.1 - 0.16 12.2 1.5 0.33 11.2 1.1 1.7 1 1 0 1 1 1 0 Extracellular mutant protein 11 DUF2564 PF10819.3 EIM92020.1 - 0.2 11.7 2.9 3.9 7.6 2.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) GPI-anchored PF10342.4 EIM92021.1 - 5.6e-07 29.9 0.9 1.7e-06 28.4 0.6 1.9 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.24 EIM92022.1 - 3.4e-42 143.7 0.0 5.7e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EIM92022.1 - 6.4e-27 93.2 0.2 2.4e-26 91.3 0.2 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EIM92022.1 - 4.6e-22 77.6 7.6 4.6e-22 77.6 5.3 2.2 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EIM92022.1 - 1.6e-06 28.3 1.2 0.00023 21.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIM92022.1 - 2.8e-06 26.5 0.0 3.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIM92022.1 - 5.1e-06 26.2 0.0 2.5e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIM92022.1 - 1.1e-05 24.8 0.0 3.2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EIM92022.1 - 1.9e-05 24.5 0.1 6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIM92022.1 - 3e-05 24.8 0.4 0.00012 22.8 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 EIM92022.1 - 3.7e-05 23.8 0.1 0.00027 21.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EIM92022.1 - 0.00019 21.3 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIM92022.1 - 0.00027 20.8 0.2 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EIM92022.1 - 0.00053 19.0 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EIM92022.1 - 0.00067 19.9 0.3 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIM92022.1 - 0.00094 18.6 0.3 0.2 11.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EIM92022.1 - 0.00097 17.9 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EIM92022.1 - 0.0027 17.3 0.2 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIM92022.1 - 0.0031 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ResIII PF04851.10 EIM92022.1 - 0.0063 16.3 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EIM92022.1 - 0.0087 15.1 0.1 2.6 7.0 0.0 2.4 1 1 1 2 2 2 1 KaiC Zeta_toxin PF06414.7 EIM92022.1 - 0.017 14.2 0.1 0.24 10.4 0.1 2.3 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIM92022.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EIM92022.1 - 0.029 14.0 2.3 0.26 10.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 EIM92022.1 - 0.032 13.8 0.0 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EIM92022.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EIM92022.1 - 0.034 13.3 0.0 0.076 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EIM92022.1 - 0.05 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TPR_1 PF00515.23 EIM92022.1 - 0.053 13.1 2.4 7.5 6.3 1.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma54_activ_2 PF14532.1 EIM92022.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF4407 PF14362.1 EIM92022.1 - 0.071 12.0 2.1 0.11 11.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Guanylate_kin PF00625.16 EIM92022.1 - 0.088 12.2 0.3 0.35 10.2 0.0 2.0 2 1 0 2 2 2 0 Guanylate kinase TPR_11 PF13414.1 EIM92022.1 - 0.21 11.2 4.6 2.4 7.8 3.0 2.3 1 1 0 1 1 1 0 TPR repeat TPR_8 PF13181.1 EIM92022.1 - 5.8 6.9 7.8 3.3 7.6 1.5 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIM92022.1 - 5.9 7.0 9.5 9.3 6.4 0.8 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat GPI-anchored PF10342.4 EIM92023.1 - 0.0022 18.4 0.0 0.0033 17.8 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 EIM92024.1 - 0.00012 20.5 4.7 0.00015 20.2 3.3 1.2 1 0 0 1 1 1 1 Transmembrane protein CCDC144C PF14915.1 EIM92024.1 - 0.97 8.2 19.9 0.036 12.9 8.6 1.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region FUSC PF04632.7 EIM92024.1 - 2.8 6.2 8.9 3.9 5.7 6.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 EIM92024.1 - 7 3.8 21.4 9.5 3.3 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pkinase PF00069.20 EIM92025.1 - 6.5e-65 218.8 0.0 8.6e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92025.1 - 1.6e-24 86.3 0.0 2.2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92025.1 - 5e-06 25.6 0.0 1.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YTV PF07639.6 EIM92025.1 - 0.054 13.2 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 YTV His_Phos_2 PF00328.17 EIM92025.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ribosomal_L19e PF01280.15 EIM92027.1 - 7.1e-60 201.0 12.3 7.1e-60 201.0 8.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e DUF349 PF03993.7 EIM92027.1 - 1.1 9.4 9.6 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MOZ_SAS PF01853.13 EIM92029.1 - 1.6e-63 213.3 1.6 1.7e-63 213.3 0.5 1.4 2 0 0 2 2 2 1 MOZ/SAS family Pkinase PF00069.20 EIM92030.1 - 9.5e-25 87.2 0.0 1.7e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92030.1 - 8.3e-12 44.7 0.0 4.5e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92030.1 - 0.0024 16.8 0.0 0.0076 15.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM92030.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPT PF03169.10 EIM92032.1 - 6.9e-184 612.7 47.6 8.2e-184 612.5 33.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aldo_ket_red PF00248.16 EIM92034.1 - 4.5e-46 156.9 0.0 5.1e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pectinesterase PF01095.14 EIM92036.1 - 5.3e-36 123.7 0.1 6.9e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Pectinesterase AAA_17 PF13207.1 EIM92037.1 - 0.002 18.9 0.1 0.011 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIM92037.1 - 0.0089 16.3 0.1 0.054 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIM92037.1 - 0.051 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 EIM92037.1 - 0.1 12.4 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Bromodomain PF00439.20 EIM92039.1 - 8.4e-27 92.9 0.3 8.6e-17 60.8 0.2 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EIM92039.1 - 1.2e-06 28.2 0.0 3.2e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 BAH domain DUF1426 PF07234.6 EIM92039.1 - 2.4 7.8 5.1 16 5.2 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1426) zf-H2C2_2 PF13465.1 EIM92040.1 - 1.7e-05 24.8 1.0 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIM92040.1 - 5e-05 23.4 1.2 9e-05 22.5 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM92040.1 - 0.0026 17.9 0.8 0.0057 16.9 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIM92040.1 - 0.011 15.3 2.2 0.021 14.4 1.5 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FYVE PF01363.16 EIM92040.1 - 0.034 14.0 0.1 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger adh_short PF00106.20 EIM92041.1 - 8.3e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92041.1 - 1e-09 38.3 0.0 2.3e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIM92041.1 - 3.9e-05 23.5 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIM92041.1 - 0.0029 17.0 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EIM92041.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EIM92041.1 - 0.022 14.7 0.2 0.078 12.9 0.1 2.0 2 1 0 2 2 2 0 NADH(P)-binding ADH_zinc_N PF00107.21 EIM92041.1 - 0.065 12.7 0.4 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EIM92041.1 - 0.091 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF328 PF03883.9 EIM92042.1 - 0.058 12.6 0.5 0.11 11.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF328) OmpH PF03938.9 EIM92042.1 - 6.3 6.7 10.7 13 5.7 7.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) OPT PF03169.10 EIM92043.1 - 4.2e-168 560.6 56.5 4.8e-168 560.4 39.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_transf_25 PF01755.12 EIM92044.1 - 7.2e-08 32.3 0.0 4.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-Apc11 PF12861.2 EIM92045.1 - 1e-40 137.4 10.8 1.2e-40 137.2 7.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIM92045.1 - 3.9e-32 110.1 10.7 4.5e-32 109.9 7.4 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIM92045.1 - 1.5e-05 24.7 17.7 5.4e-05 22.9 12.1 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIM92045.1 - 0.0041 16.8 11.5 0.083 12.6 8.5 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIM92045.1 - 0.0058 16.6 6.5 0.0058 16.6 4.5 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIM92045.1 - 0.038 13.5 4.0 0.07 12.6 2.8 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EIM92045.1 - 0.14 11.8 15.6 0.85 9.3 10.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EIM92045.1 - 0.56 10.2 6.0 0.91 9.5 4.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIM92045.1 - 5.5 7.2 8.9 23 5.2 6.1 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain TPR_11 PF13414.1 EIM92046.1 - 4.1e-18 64.8 5.0 6.4e-15 54.5 0.5 2.5 1 1 1 2 2 2 2 TPR repeat SET PF00856.23 EIM92046.1 - 1.2e-09 38.6 0.0 4.2e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.12 EIM92046.1 - 2.9e-09 36.1 5.6 0.00038 20.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIM92046.1 - 4.5e-09 35.5 1.6 0.00034 20.0 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIM92046.1 - 7.8e-06 25.6 1.4 0.0021 17.8 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM92046.1 - 4.3e-05 24.0 8.8 0.007 17.0 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM92046.1 - 0.0003 21.0 0.3 0.0029 17.9 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIM92046.1 - 0.0082 15.9 0.1 0.025 14.4 0.1 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EIM92046.1 - 0.022 14.6 1.3 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIM92047.1 - 2.8e-12 46.0 0.1 5.3e-07 29.2 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIM92047.1 - 5.5e-08 32.1 0.7 5.9e-05 22.6 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM92047.1 - 5.2e-06 26.9 0.1 0.00093 19.8 0.1 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIM92047.1 - 1.2e-05 24.6 0.4 0.00022 20.7 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM92047.1 - 0.0047 16.7 0.4 1.2 8.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIM92047.1 - 0.013 15.4 0.5 0.7 9.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIM92047.1 - 0.058 14.0 1.4 2 9.2 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat SET PF00856.23 EIM92048.1 - 6.4e-06 26.5 0.0 0.00034 20.9 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EIM92048.1 - 5.2e-05 22.8 0.2 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIM92048.1 - 0.0003 20.4 1.0 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIM92048.1 - 0.0017 18.1 0.3 0.0097 15.7 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM92048.1 - 0.033 14.8 1.1 0.08 13.6 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIM92048.1 - 0.058 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI PF01399.22 EIM92049.1 - 1.5e-08 34.8 0.9 3.4e-08 33.7 0.6 1.6 1 0 0 1 1 1 1 PCI domain Rgp1 PF08737.5 EIM92050.1 - 1.4e-43 149.5 0.0 4.5e-43 147.8 0.0 1.8 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 EIM92050.1 - 0.036 14.1 0.1 26 4.9 0.0 3.5 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain DUF1266 PF06889.6 EIM92051.1 - 0.14 11.9 0.2 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) PSP1 PF04468.7 EIM92052.1 - 1.3e-32 111.6 1.6 1.3e-32 111.6 1.1 1.6 2 0 0 2 2 2 1 PSP1 C-terminal conserved region tRNA-synt_1c PF00749.16 EIM92053.1 - 4.8e-82 275.1 0.0 1e-81 274.0 0.0 1.5 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Phosphoprotein PF00922.12 EIM92053.1 - 0.0062 15.7 3.5 0.0097 15.1 2.4 1.2 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein tRNA-synt_1d PF00750.14 EIM92053.1 - 0.047 12.5 0.0 1.7 7.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) SSP160 PF06933.6 EIM92053.1 - 2.6 5.9 5.1 3.6 5.4 3.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-UBR PF02207.15 EIM92055.1 - 1.5e-13 50.2 19.8 1.5e-13 50.2 13.7 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EIM92055.1 - 4e-09 36.0 0.1 9.8e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 EIM92055.1 - 0.027 13.7 0.1 0.07 12.3 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL TRAPP PF04051.11 EIM92056.1 - 7.3e-29 100.2 0.0 8.8e-29 99.9 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_fiss_reg PF05308.6 EIM92056.1 - 0.01 15.2 0.5 0.015 14.6 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator NeA_P2 PF12312.3 EIM92056.1 - 0.081 12.1 0.4 0.25 10.5 0.2 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein adh_short PF00106.20 EIM92058.1 - 6.7e-30 104.1 0.3 9.9e-30 103.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM92058.1 - 7.1e-26 91.4 1.3 4.4e-25 88.8 0.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM92058.1 - 3.9e-15 55.9 0.3 6.2e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIM92058.1 - 0.1 12.2 0.5 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain A_deaminase PF00962.17 EIM92059.1 - 6.9e-24 84.3 0.0 9.3e-23 80.6 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF3752 PF12572.3 EIM92060.1 - 3.5e-35 121.3 11.7 3.5e-35 121.3 8.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) EURL PF06937.6 EIM92060.1 - 0.55 9.6 3.3 0.74 9.1 2.3 1.2 1 0 0 1 1 1 0 EURL protein NmrA PF05368.8 EIM92062.1 - 1.9e-21 76.4 0.0 2.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIM92062.1 - 3.6e-12 46.6 0.0 5.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIM92062.1 - 2.8e-06 26.9 0.0 1.4e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM92062.1 - 5.1e-06 25.4 0.0 7.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIM92062.1 - 0.00016 21.6 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92062.1 - 0.0015 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EIM92062.1 - 0.036 12.9 0.2 0.091 11.6 0.1 1.7 1 1 1 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EIM92062.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein BcsB PF03170.8 EIM92062.1 - 0.067 11.1 0.0 0.091 10.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit G-alpha PF00503.15 EIM92063.1 - 1.1e-105 353.5 0.1 1.4e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIM92063.1 - 2.2e-11 43.3 2.9 1.1e-07 31.2 0.4 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EIM92063.1 - 0.0013 19.2 0.1 0.78 10.2 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EIM92063.1 - 0.02 14.3 0.2 3.2 7.1 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIM92063.1 - 0.021 14.7 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.5 EIM92063.1 - 0.11 11.7 0.3 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EIM92063.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIM92063.1 - 0.13 11.6 0.0 6.4 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 EIM92063.1 - 0.28 10.2 5.8 3.8 6.5 0.4 2.8 2 2 0 2 2 2 0 Gtr1/RagA G protein conserved region Alpha_kinase PF02816.13 EIM92067.1 - 5.7e-12 45.6 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family RNHCP PF12647.2 EIM92067.1 - 0.082 12.7 2.2 0.19 11.6 1.5 1.6 1 0 0 1 1 1 0 RNHCP domain EutB PF06751.6 EIM92069.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) HTH_21 PF13276.1 EIM92073.1 - 0.19 11.7 1.7 2.8 8.0 0.0 3.1 4 0 0 4 4 4 0 HTH-like domain WD40 PF00400.27 EIM92075.1 - 2.8e-14 52.3 0.2 0.0044 16.8 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Luteo_Vpg PF01659.11 EIM92075.1 - 0.052 13.2 1.0 6 6.6 0.2 2.5 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein DUF2415 PF10313.4 EIM92075.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.5 EIM92076.1 - 4.8e-17 61.9 0.3 1.5e-15 57.0 0.0 3.1 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like SNAP PF14938.1 EIM92076.1 - 0.0074 15.4 0.8 0.016 14.3 0.1 1.9 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 EIM92076.1 - 0.013 15.0 0.6 1.7 8.3 0.3 3.3 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.1 EIM92076.1 - 0.075 13.3 0.1 0.075 13.3 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.15 EIM92077.1 - 0.035 13.4 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 Cyclin PF08613.6 EIM92078.1 - 2.6e-19 70.0 0.1 4.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIM92078.1 - 5.3e-08 32.4 0.0 8.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs3p PF12271.3 EIM92080.1 - 2.4e-117 391.1 22.0 2.7e-117 390.9 15.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit WD40 PF00400.27 EIM92081.1 - 1.7e-40 135.4 7.2 1.9e-08 33.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIM92081.1 - 1e-09 37.1 0.3 0.00018 19.8 0.0 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 EIM92081.1 - 0.057 13.2 12.0 0.091 12.6 8.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1024 PF06260.7 EIM92081.1 - 0.06 13.4 1.6 0.13 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) IncA PF04156.9 EIM92081.1 - 0.24 10.9 6.5 0.43 10.1 4.5 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIM92081.1 - 4.2 5.1 6.1 5.8 4.6 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIM92081.1 - 4.8 6.1 7.9 7.6 5.4 5.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BC10 PF06726.7 EIM92082.1 - 4.4e-10 39.4 12.5 9.1e-10 38.4 8.7 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF3678 PF12435.3 EIM92082.1 - 0.15 11.6 3.2 0.46 10.0 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) CS PF04969.11 EIM92083.1 - 0.0021 18.5 0.1 0.004 17.6 0.0 1.6 2 0 0 2 2 2 1 CS domain HAD_2 PF13419.1 EIM92084.1 - 3.7e-20 72.8 0.0 4.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIM92084.1 - 3.6e-12 45.8 0.1 1.6e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EIM92084.1 - 4.8e-11 43.4 0.0 2.6e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIM92084.1 - 0.0017 18.5 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.21 EIM92086.1 - 2.1e-10 40.4 0.3 4.2e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIM92086.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal Dynein_heavy PF03028.10 EIM92087.1 - 6.7e-181 602.9 0.4 1.3e-180 601.9 0.0 1.6 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EIM92087.1 - 6.4e-131 436.6 7.1 6.4e-131 436.6 4.9 3.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EIM92087.1 - 3.4e-79 265.6 0.0 1.5e-78 263.4 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EIM92087.1 - 1.7e-45 154.6 0.1 4.4e-45 153.2 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 EIM92087.1 - 2.3e-45 154.8 5.0 4.3e-45 153.9 3.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 EIM92087.1 - 2.5e-44 151.2 0.2 3.4e-43 147.5 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 EIM92087.1 - 1.5e-27 96.0 0.1 3.6e-11 42.9 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EIM92087.1 - 4.5e-20 71.8 0.0 1.6e-19 70.0 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 EIM92087.1 - 2.4e-13 50.4 0.1 0.00027 21.1 0.0 4.9 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM92087.1 - 1.7e-12 47.6 0.0 0.023 14.8 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EIM92087.1 - 5.8e-11 42.4 1.8 0.2 11.4 0.0 5.6 5 1 0 5 5 5 3 AAA domain AAA_16 PF13191.1 EIM92087.1 - 1.1e-09 38.4 3.8 0.11 12.4 0.0 6.8 7 0 0 7 7 5 2 AAA ATPase domain AAA_17 PF13207.1 EIM92087.1 - 1.7e-08 35.3 0.0 0.11 13.2 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EIM92087.1 - 1.4e-07 31.8 3.4 0.018 15.3 0.0 6.0 6 0 0 6 6 6 1 AAA domain AAA_14 PF13173.1 EIM92087.1 - 1.6e-07 31.2 0.0 0.56 10.1 0.0 6.0 7 0 0 7 7 5 2 AAA domain T2SE PF00437.15 EIM92087.1 - 2.1e-06 26.8 0.0 0.043 12.7 0.0 3.7 4 0 0 4 4 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EIM92087.1 - 7.1e-06 25.6 0.0 0.48 9.8 0.0 4.1 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EIM92087.1 - 8.9e-06 25.3 0.0 0.87 9.3 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EIM92087.1 - 1.3e-05 24.5 0.8 0.5 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EIM92087.1 - 0.00024 20.5 0.1 0.72 9.4 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIM92087.1 - 0.00086 18.4 0.0 2.3 7.2 0.0 4.4 4 0 0 4 4 4 1 Zeta toxin IstB_IS21 PF01695.12 EIM92087.1 - 0.0016 17.9 1.0 0.36 10.2 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIM92087.1 - 0.014 14.7 0.9 1.4 8.2 0.0 4.3 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.22 EIM92087.1 - 0.016 15.4 3.7 12 6.2 0.0 4.5 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.17 EIM92087.1 - 0.017 15.3 0.1 39 4.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase PduV-EutP PF10662.4 EIM92087.1 - 0.021 14.3 0.7 7.5 6.0 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EIM92087.1 - 0.029 14.1 1.3 3 7.6 0.0 4.2 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit MobB PF03205.9 EIM92087.1 - 0.037 13.7 0.8 24 4.5 0.0 4.0 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B IFT46_B_C PF12317.3 EIM92087.1 - 0.1 11.9 10.8 0.18 11.1 0.1 3.5 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal PLRV_ORF5 PF01690.12 EIM92087.1 - 6.4 5.8 2.7 12 4.9 1.9 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LSM PF01423.17 EIM92088.1 - 2.3e-14 52.6 0.5 3.3e-14 52.1 0.4 1.2 1 0 0 1 1 1 1 LSM domain Pex2_Pex12 PF04757.9 EIM92089.1 - 6.1e-22 78.1 4.3 1.1e-21 77.3 3.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 EIM92089.1 - 1.5e-09 37.3 2.9 2.2e-09 36.8 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM92089.1 - 6.3e-09 35.7 6.5 9.7e-09 35.1 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIM92089.1 - 8.1e-09 35.1 7.4 1.4e-08 34.4 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM92089.1 - 8.2e-08 31.7 5.0 1.3e-07 31.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM92089.1 - 3.5e-07 29.8 5.8 5.4e-07 29.2 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIM92089.1 - 0.00012 22.1 2.3 0.00022 21.2 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIM92089.1 - 0.0021 17.8 6.7 0.0042 16.9 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TerY-C PF15616.1 EIM92089.1 - 0.0049 16.8 1.2 0.0081 16.0 0.9 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain zf-Apc11 PF12861.2 EIM92089.1 - 0.0052 16.5 0.6 0.0093 15.7 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIM92089.1 - 0.0081 15.8 0.9 0.015 15.0 0.2 1.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EIM92089.1 - 0.015 14.8 2.8 0.028 13.9 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EIM92089.1 - 0.24 10.9 6.0 0.39 10.3 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EIM92089.1 - 6.3 6.7 8.0 11 5.9 5.3 1.6 1 1 0 1 1 1 0 IBR domain 2-Hacid_dh_C PF02826.14 EIM92090.1 - 4.2e-52 175.8 0.0 8.5e-52 174.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIM92090.1 - 2e-32 111.4 0.0 2.6e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIM92090.1 - 0.00034 20.4 0.1 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EIM92090.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EIM92090.1 - 0.084 12.3 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 ACT domain His_biosynth PF00977.16 EIM92091.1 - 2.6e-40 138.1 0.1 3.8e-39 134.2 0.1 2.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EIM92091.1 - 2e-28 99.1 0.0 3.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EIM92091.1 - 4.7e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EIM92091.1 - 5.5e-07 29.3 0.0 0.00022 20.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EIM92091.1 - 0.022 14.1 0.1 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 EphA2_TM PF14575.1 EIM92091.1 - 0.039 14.3 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pal1 PF08316.6 EIM92092.1 - 8.4e-15 55.4 0.3 8.4e-15 55.4 0.2 2.3 3 0 0 3 3 3 1 Pal1 cell morphology protein FA_desaturase PF00487.19 EIM92093.1 - 1.4e-33 116.4 28.1 2.3e-33 115.7 19.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIM92093.1 - 8.8e-08 31.8 0.3 2.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13e PF01294.13 EIM92094.1 - 1.1e-65 220.4 5.4 1.6e-65 219.9 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e SprB PF13573.1 EIM92096.1 - 0.00041 19.8 1.2 0.048 13.2 0.1 3.4 2 0 0 2 2 2 1 SprB repeat SKG6 PF08693.5 EIM92096.1 - 0.0048 16.1 2.4 0.012 14.9 0.2 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EIM92096.1 - 0.074 11.3 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CBM_4_9 PF02018.12 EIM92096.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Romo1 PF10247.4 EIM92097.1 - 3.2e-24 84.9 6.8 4.2e-24 84.5 4.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 UPF0014 PF03649.8 EIM92098.1 - 1.1e-41 142.6 11.0 1.5e-41 142.2 7.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.17 EIM92098.1 - 6.2 6.2 15.6 0.27 10.7 5.6 2.3 1 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component Lipase_GDSL PF00657.17 EIM92099.1 - 3.1e-06 27.2 0.0 5.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.16 EIM92100.1 - 5.2e-91 305.2 0.0 5.9e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF269 PF03270.8 EIM92103.1 - 0.035 14.1 0.4 0.46 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF269 Elong_Iki1 PF10483.4 EIM92104.1 - 7.8e-08 32.0 0.0 7.8e-08 32.0 0.0 3.0 3 1 0 3 3 3 1 Elongator subunit Iki1 DLH PF01738.13 EIM92106.1 - 1.1e-26 93.5 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM92106.1 - 0.00024 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EIM92106.1 - 0.0045 16.4 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) GTP_EFTU PF00009.22 EIM92107.1 - 1.6e-55 187.4 0.0 2.6e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIM92107.1 - 3e-37 126.7 0.0 7.5e-37 125.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIM92107.1 - 1.3e-16 60.4 0.7 1.3e-16 60.4 0.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIM92107.1 - 8.5e-05 22.1 0.3 0.00029 20.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIM92107.1 - 0.0048 16.8 0.3 0.014 15.3 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 EIM92107.1 - 0.052 13.3 0.2 0.22 11.3 0.0 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Pkinase PF00069.20 EIM92108.1 - 1e-43 149.3 0.0 1.7e-40 138.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92108.1 - 1e-16 60.8 0.0 1.3e-14 53.9 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92108.1 - 1.9e-06 27.0 0.0 3.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIM92108.1 - 0.0005 19.1 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIM92108.1 - 0.0035 17.0 0.1 0.0078 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L32e PF01655.13 EIM92109.1 - 2.8e-48 162.5 0.8 3.3e-48 162.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Copper-fist PF00649.13 EIM92111.1 - 2.8e-21 74.4 0.5 2.8e-21 74.4 0.3 2.5 2 0 0 2 2 2 1 Copper fist DNA binding domain F-box PF00646.28 EIM92112.1 - 3.4e-09 36.1 0.5 1.4e-08 34.1 0.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIM92112.1 - 4.3e-08 32.7 0.4 4.3e-08 32.7 0.3 3.1 3 0 0 3 3 3 1 F-box-like UQ_con PF00179.21 EIM92113.1 - 3.1e-25 88.2 0.0 3.8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM92113.1 - 0.00015 21.5 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIM92113.1 - 0.00031 20.6 0.0 0.00074 19.3 0.0 1.5 1 1 1 2 2 2 1 RWD domain UEV PF05743.8 EIM92113.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain Porphobil_deam PF01379.15 EIM92114.1 - 4.2e-74 248.0 0.0 7.1e-74 247.3 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EIM92114.1 - 1.7e-17 63.2 0.4 3.6e-17 62.2 0.3 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PASTA PF03793.14 EIM92114.1 - 0.087 12.4 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 PASTA domain Nfu_N PF08712.6 EIM92115.1 - 2.2e-30 104.1 0.0 4.8e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EIM92115.1 - 4.3e-23 80.8 0.1 7e-23 80.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Glyco_trans_1_4 PF13692.1 EIM92116.1 - 1.4e-21 77.0 0.0 2.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIM92116.1 - 4.7e-07 30.0 0.6 1.2e-06 28.7 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EIM92116.1 - 3.6e-06 26.5 0.0 7.8e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIM92116.1 - 5.8e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_18 PF00704.23 EIM92118.1 - 1e-64 219.2 1.4 1.4e-64 218.6 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.1 EIM92118.1 - 0.005 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 Glyco_hydro_85 PF03644.8 EIM92118.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Peptidase_M24 PF00557.19 EIM92119.1 - 7.7e-46 156.2 0.1 9.3e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 GTP_EFTU PF00009.22 EIM92120.1 - 3.5e-64 215.7 0.1 5e-64 215.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIM92120.1 - 1.5e-37 127.8 0.0 3.2e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIM92120.1 - 3.3e-21 74.9 0.0 6.8e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIM92120.1 - 1.7e-13 50.1 0.0 4.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIM92120.1 - 1.4e-12 47.5 0.1 5.5e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM92120.1 - 5.5e-07 29.5 0.2 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIM92120.1 - 0.017 14.6 0.5 0.072 12.5 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_membrane PF00664.18 EIM92121.1 - 2.3e-44 151.8 25.6 2.7e-22 79.4 4.1 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 EIM92121.1 - 2.5e-40 137.9 0.0 5.7e-22 78.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIM92121.1 - 1.9e-12 46.9 0.0 0.00015 21.1 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM92121.1 - 1.5e-08 34.9 3.3 0.032 14.2 0.1 3.9 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 EIM92121.1 - 1.1e-07 31.4 0.0 0.0059 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIM92121.1 - 1.3e-06 28.9 0.1 0.00016 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIM92121.1 - 5.8e-06 25.7 0.1 0.05 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM92121.1 - 1.2e-05 25.3 0.2 0.1 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EIM92121.1 - 8e-05 21.6 0.0 0.025 13.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EIM92121.1 - 0.0001 22.0 1.2 0.54 9.9 0.0 3.1 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EIM92121.1 - 0.00011 21.6 0.2 0.55 9.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EIM92121.1 - 0.00015 21.6 1.1 0.035 13.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EIM92121.1 - 0.00022 22.0 0.4 0.95 10.2 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIM92121.1 - 0.00023 21.3 0.2 0.24 11.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EIM92121.1 - 0.00094 19.6 0.0 2.7 8.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein Adeno_IVa2 PF02456.10 EIM92121.1 - 0.0012 17.6 0.0 0.006 15.2 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 EIM92121.1 - 0.0016 18.3 0.1 0.98 9.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM92121.1 - 0.0035 16.5 0.1 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DEAD PF00270.24 EIM92121.1 - 0.0056 16.1 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EIM92121.1 - 0.0069 15.8 0.7 2 7.7 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EIM92121.1 - 0.008 16.4 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIM92121.1 - 0.0088 15.1 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 EIM92121.1 - 0.0096 15.6 0.1 0.18 11.4 0.0 2.5 3 0 0 3 3 2 1 Archaeal ATPase AAA_5 PF07728.9 EIM92121.1 - 0.014 15.0 0.0 4.4 7.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIM92121.1 - 0.015 15.1 0.1 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIM92121.1 - 0.024 14.4 0.1 1.9 8.3 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain ATP-synt_ab PF00006.20 EIM92121.1 - 0.025 14.0 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EIM92121.1 - 0.027 14.1 0.1 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 EIM92121.1 - 0.029 13.6 0.9 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.4 EIM92121.1 - 0.029 12.9 0.6 1.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.12 EIM92121.1 - 0.06 12.7 0.1 6.1 6.2 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein cobW PF02492.14 EIM92121.1 - 0.069 12.5 0.9 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 EIM92121.1 - 0.071 12.9 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Tubulin PF00091.20 EIM92121.1 - 0.084 12.6 0.4 5.3 6.7 0.1 2.6 3 0 0 3 3 2 0 Tubulin/FtsZ family, GTPase domain AAA PF00004.24 EIM92121.1 - 0.19 11.9 2.0 1.2 9.3 0.0 3.2 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EIM92122.1 - 1.3e-71 240.8 0.0 4.9e-49 166.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM92122.1 - 1.6e-11 43.8 0.0 3.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EIM92122.1 - 0.00029 20.5 3.2 0.00029 20.5 2.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain HIRAN PF08797.6 EIM92122.1 - 0.0064 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.10 EIM92122.1 - 0.074 12.8 0.0 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EIM92122.1 - 0.36 10.5 10.5 0.014 15.0 2.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.7 EIM92123.1 - 1.1e-22 79.8 0.8 1.9e-22 79.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM92123.1 - 2.1e-14 53.1 0.0 3.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM92123.1 - 0.00036 19.7 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIM92123.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EIM92123.1 - 0.0075 17.1 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIM92123.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EIM92123.1 - 0.1 13.0 0.2 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UNC-93 PF05978.11 EIM92124.1 - 1e-11 44.5 4.1 1e-11 44.5 2.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EIM92124.1 - 9.8e-10 37.6 30.8 2e-09 36.6 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM92124.1 - 3.1e-06 26.0 19.4 0.0025 16.4 0.4 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter CUE PF02845.11 EIM92125.1 - 0.00014 21.2 0.0 0.00042 19.7 0.0 1.8 1 0 0 1 1 1 1 CUE domain SKN1 PF03935.10 EIM92126.1 - 3.6e-190 632.3 4.3 4.6e-190 632.0 3.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EIM92126.1 - 0.00034 19.9 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EIM92127.1 - 4.7e-194 645.2 2.5 5.7e-194 644.9 1.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EIM92127.1 - 4.3e-05 22.8 0.2 0.00048 19.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 BTB PF00651.26 EIM92128.1 - 3.9e-08 33.2 0.0 5.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain UQ_con PF00179.21 EIM92129.1 - 5.8e-21 74.3 0.0 9.3e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aldose_epim PF01263.15 EIM92130.1 - 5e-60 203.1 0.9 5.6e-60 202.9 0.6 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ribonuc_P_40 PF08584.6 EIM92130.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.11 EIM92131.1 - 5.8e-34 117.3 49.9 8.4e-33 113.5 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM92131.1 - 4e-15 55.3 27.2 4.9e-14 51.7 18.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter F-box PF00646.28 EIM92132.1 - 8.7e-08 31.6 1.1 2.7e-07 30.0 0.2 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EIM92132.1 - 2.5e-07 30.3 0.2 7e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF619 PF04768.8 EIM92133.1 - 3.8e-35 120.8 0.1 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) AA_kinase PF00696.23 EIM92133.1 - 0.035 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family Mito_carr PF00153.22 EIM92135.1 - 3.7e-69 228.5 6.5 2e-23 81.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rav1p_C PF12234.3 EIM92137.1 - 2.7e-177 590.7 0.0 6.6e-177 589.4 0.0 1.6 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EIM92137.1 - 0.12 12.3 6.3 1.8 8.5 0.2 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Fasciclin PF02469.17 EIM92138.1 - 1.9e-69 231.5 0.0 7.2e-17 61.5 0.0 5.7 5 1 0 5 5 5 5 Fasciclin domain F-box-like PF12937.2 EIM92140.1 - 5.2e-07 29.2 4.6 5.2e-07 29.2 3.2 2.4 2 2 0 2 2 2 1 F-box-like GDI PF00996.13 EIM92141.1 - 3.9e-208 691.1 0.0 4.5e-208 690.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rap1-DNA-bind PF09197.5 EIM92142.1 - 0.00033 21.1 1.0 1.2 9.6 0.0 3.1 3 0 0 3 3 3 2 Rap1, DNA-binding Aldedh PF00171.17 EIM92143.1 - 7e-127 423.5 0.2 8.2e-127 423.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM92143.1 - 0.0024 16.6 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LMWPc PF01451.16 EIM92144.1 - 1.3e-35 122.7 0.0 1.5e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.10 EIM92145.1 - 1.5e-14 53.7 0.0 1.5e-14 53.7 0.0 2.7 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein adh_short PF00106.20 EIM92146.1 - 7.9e-28 97.4 0.1 1.2e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM92146.1 - 2.7e-21 76.4 0.0 4.9e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM92146.1 - 1.5e-08 34.5 0.2 3.5e-08 33.3 0.1 1.7 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EIM92146.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Seipin PF06775.9 EIM92147.1 - 5.5e-17 61.9 0.0 1.3e-15 57.4 0.0 2.2 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PD-C2-AF1 PF09310.5 EIM92148.1 - 0.015 14.4 0.4 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 Fungal_trans PF04082.13 EIM92150.1 - 1.6e-10 40.2 0.1 3.2e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM92150.1 - 2e-06 27.5 13.9 3.7e-06 26.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIM92151.1 - 2.7e-06 26.4 0.1 3.4e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain P12 PF12669.2 EIM92152.1 - 0.16 12.1 3.8 0.29 11.3 2.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Ras PF00071.17 EIM92153.1 - 4.9e-54 182.0 0.0 5.6e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM92153.1 - 1.5e-17 64.2 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM92153.1 - 1.8e-07 30.5 0.0 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family His_Phos_1 PF00300.17 EIM92154.1 - 3.6e-29 101.9 0.1 4.3e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Filament PF00038.16 EIM92155.1 - 0.0001 21.8 121.4 0.00011 21.7 21.2 4.9 1 1 4 5 5 5 4 Intermediate filament protein TMF_TATA_bd PF12325.3 EIM92155.1 - 0.0019 17.9 7.3 0.0019 17.9 5.1 10.0 1 1 7 10 10 10 2 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIM92155.1 - 0.0086 15.6 8.9 0.0086 15.6 6.2 7.6 1 1 4 5 5 5 1 IncA protein Reo_sigmaC PF04582.7 EIM92155.1 - 1.3 8.1 56.3 0.24 10.5 6.2 5.9 1 1 3 5 5 5 0 Reovirus sigma C capsid protein Mito_carr PF00153.22 EIM92156.1 - 5.1e-30 103.0 8.9 2.3e-14 52.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein XRCC1_N PF01834.11 EIM92156.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain ketoacyl-synt PF00109.21 EIM92157.1 - 9.9e-53 179.2 0.0 1.6e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIM92157.1 - 4.1e-35 121.6 0.0 7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EIM92157.1 - 4.8e-31 108.0 0.0 1.5e-30 106.3 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EIM92157.1 - 5.6e-31 107.6 0.0 1.2e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIM92157.1 - 4.6e-25 88.4 0.0 9.2e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EIM92157.1 - 5.5e-17 61.7 0.0 3.4e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EIM92157.1 - 5.9e-13 49.5 0.1 1.7e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EIM92157.1 - 8.3e-06 25.9 0.1 3.4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 EIM92157.1 - 7.4e-05 22.3 0.6 0.00027 20.5 0.4 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EIM92157.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Peptidase_M9_N PF08453.5 EIM92157.1 - 0.93 8.8 0.0 1.6 7.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal MFS_1 PF07690.11 EIM92159.1 - 5.2e-19 68.1 48.8 6.1e-19 67.9 27.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_4 PF07993.7 EIM92160.1 - 2.1e-32 112.0 0.0 3.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIM92160.1 - 6.1e-30 103.9 0.1 1.6e-28 99.2 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIM92160.1 - 5.8e-12 45.5 0.0 4.5e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIM92160.1 - 0.00011 22.3 0.1 0.00069 19.8 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EIM92160.1 - 0.0068 16.3 0.5 0.016 15.0 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92160.1 - 0.029 14.0 0.3 0.063 12.9 0.2 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EIM92160.1 - 0.18 10.4 0.0 0.58 8.8 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PPR_1 PF12854.2 EIM92160.1 - 1.7 8.1 3.2 3.4 7.2 0.2 2.5 2 0 0 2 2 2 0 PPR repeat Mpv17_PMP22 PF04117.7 EIM92161.1 - 9e-07 28.4 1.5 1.4e-06 27.8 0.6 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MOSC_N PF03476.11 EIM92162.1 - 8e-17 61.0 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EIM92162.1 - 1.3e-06 27.9 0.0 2.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 MOSC domain FTR_C PF02741.10 EIM92162.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 FTR, proximal lobe LCCL PF03815.14 EIM92163.1 - 1.3e-12 47.5 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF3094 PF11293.3 EIM92163.1 - 0.013 14.9 0.2 0.033 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Hex_IIIa PF02455.11 EIM92165.1 - 0.0003 19.6 3.2 0.00035 19.3 2.2 1.0 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) DUF3435 PF11917.3 EIM92165.1 - 0.042 12.5 4.6 0.049 12.3 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) OmpH PF03938.9 EIM92165.1 - 0.57 10.1 14.8 0.91 9.4 10.3 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) WW PF00397.21 EIM92165.1 - 0.61 10.0 5.0 0.29 11.0 0.4 2.4 2 0 0 2 2 2 0 WW domain Dehydrin PF00257.14 EIM92165.1 - 1 9.6 17.4 2.6 8.3 12.0 1.8 1 1 0 1 1 1 0 Dehydrin TRAPPC-Trs85 PF12739.2 EIM92166.1 - 1e-27 96.8 0.0 8e-24 84.0 0.0 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 EIM92166.1 - 0.0013 16.2 0.1 0.7 7.1 0.0 2.0 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Cbl_N3 PF02762.9 EIM92166.1 - 0.098 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain TPR_16 PF13432.1 EIM92166.1 - 1 10.1 4.2 1.4 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PALP PF00291.20 EIM92167.1 - 1.8e-56 191.6 0.0 2.2e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_3 PF07859.8 EIM92168.1 - 6.6e-46 156.5 0.0 8.5e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIM92168.1 - 0.00093 18.0 0.1 0.0017 17.1 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIM92168.1 - 0.012 14.8 0.0 0.55 9.4 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Exo_endo_phos PF03372.18 EIM92169.1 - 5.1e-20 72.4 0.0 7.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyridox_ox_2 PF12900.2 EIM92170.1 - 8.3e-31 106.7 0.0 1.2e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4139 PF13598.1 EIM92171.1 - 1.9e-64 218.0 0.5 3.2e-64 217.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EIM92171.1 - 6.1e-11 42.7 6.6 7e-09 36.0 0.0 3.7 3 0 0 3 3 3 2 N-terminal domain of unknown function (DUF4140) HPPK PF01288.15 EIM92171.1 - 0.032 13.9 0.3 0.063 13.0 0.2 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Kinetocho_Slk19 PF12709.2 EIM92171.1 - 1.1 9.3 6.3 1.3 9.1 1.4 2.5 2 0 0 2 2 2 0 Central kinetochore-associated APG12 PF04110.8 EIM92172.1 - 2.9e-28 97.8 0.1 3.3e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF605 PF04652.11 EIM92174.1 - 3.1e-54 184.8 0.0 3.5e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Vta1 like PhzC-PhzF PF02567.11 EIM92174.1 - 0.08 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein adh_short_C2 PF13561.1 EIM92175.1 - 1.3e-31 110.2 0.0 1.5e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM92175.1 - 1.6e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92175.1 - 3.6e-05 23.4 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Arrestin_N PF00339.24 EIM92177.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FR47 PF08445.5 EIM92178.1 - 4.3e-10 39.2 0.0 8.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EIM92178.1 - 1.8e-08 34.2 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM92178.1 - 5.2e-07 29.7 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIM92178.1 - 1.9e-06 27.9 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM92178.1 - 4e-05 23.5 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM92178.1 - 0.00058 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EIM92178.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.1 EIM92178.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_P_pop3 PF08228.6 EIM92180.1 - 1.8e-14 53.8 0.0 2.9e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 dCMP_cyt_deam_1 PF00383.17 EIM92181.1 - 1.3e-25 88.9 0.9 1.9e-25 88.4 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MBD PF01429.14 EIM92181.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain AAA_17 PF13207.1 EIM92181.1 - 0.0076 17.0 0.0 0.017 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain HEAT PF02985.17 EIM92182.1 - 0.0036 17.2 3.8 1.3 9.3 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EIM92182.1 - 0.44 11.0 5.3 50 4.5 0.1 4.5 3 0 0 3 3 3 0 HEAT-like repeat Chorismate_bind PF00425.13 EIM92183.1 - 2.3e-61 207.3 0.0 1.1e-60 205.1 0.0 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EIM92183.1 - 6.3e-31 107.3 0.0 9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EIM92183.1 - 8.7e-20 71.1 0.0 3e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EIM92183.1 - 7.1e-06 25.6 0.9 4.1e-05 23.1 0.6 2.0 1 1 0 1 1 1 1 Peptidase C26 2OG-FeII_Oxy PF03171.15 EIM92184.1 - 0.0019 18.4 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIM92184.1 - 0.0049 17.4 0.0 0.0078 16.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pro_isomerase PF00160.16 EIM92185.1 - 4.2e-45 153.7 0.9 4.6e-45 153.5 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UQ_con PF00179.21 EIM92186.1 - 2.2e-38 130.8 0.1 2.8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIM92186.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 EIM92186.1 - 0.03 14.0 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EIM92186.1 - 0.09 12.6 0.2 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain Nop52 PF05997.7 EIM92188.1 - 9.1e-66 221.3 0.0 1.5e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 EIM92188.1 - 8.1e-05 22.0 0.0 0.00016 21.0 0.0 1.5 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II RabGAP-TBC PF00566.13 EIM92189.1 - 1.3e-26 93.4 0.0 1.8e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spc97_Spc98 PF04130.8 EIM92190.1 - 5.3e-63 213.1 0.0 8.6e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family I-set PF07679.11 EIM92191.1 - 0.0017 18.1 0.0 1.3 8.9 0.0 4.2 5 0 0 5 5 5 1 Immunoglobulin I-set domain Serglycin PF04360.7 EIM92191.1 - 0.052 13.2 0.5 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Serglycin PBP1_TM PF14812.1 EIM92191.1 - 0.26 11.6 2.8 0.57 10.5 2.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin PF00085.15 EIM92192.1 - 1.3e-27 95.4 0.0 1.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIM92192.1 - 5.8e-07 29.5 0.0 7.3e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIM92192.1 - 6.3e-06 26.3 0.1 3.6e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EIM92192.1 - 0.00037 20.1 0.1 0.00075 19.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family DUF2847 PF11009.3 EIM92192.1 - 0.0012 18.4 0.1 0.0035 16.9 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2847) Thioredoxin_7 PF13899.1 EIM92192.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIM92192.1 - 0.0031 17.0 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EIM92192.1 - 0.013 15.0 0.2 0.036 13.6 0.1 1.6 1 1 1 2 2 2 0 Redoxin HHV6-IE PF03753.8 EIM92192.1 - 0.07 10.6 0.0 0.096 10.1 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Histone PF00125.19 EIM92193.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM92193.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIM92193.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIM92193.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIM92193.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIM92193.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.2 EIM92194.1 - 3.8e-06 26.5 1.0 1e-05 25.1 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIM92194.1 - 0.00012 21.6 2.2 0.00022 20.7 0.5 2.3 3 0 0 3 3 3 1 F-box domain NUFIP1 PF10453.4 EIM92196.1 - 4.7e-17 61.2 1.3 1.4e-16 59.7 0.9 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) KH_1 PF00013.24 EIM92197.1 - 3.7e-40 135.3 9.0 7.7e-16 57.4 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIM92197.1 - 1.1e-26 91.9 10.7 8.3e-10 38.0 1.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIM92197.1 - 3.7e-11 42.5 0.7 0.00097 18.7 0.0 3.5 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EIM92197.1 - 2.5e-09 36.5 5.2 0.025 14.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EIM92197.1 - 0.00015 21.4 3.4 0.25 11.1 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EIM92197.1 - 0.073 12.5 0.8 7.1 6.0 0.0 2.9 2 1 0 3 3 3 0 dUTPase Fungal_trans PF04082.13 EIM92198.1 - 1.8e-35 122.0 0.0 3.5e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM92198.1 - 4.3e-07 29.7 9.9 8.1e-07 28.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_C PF05193.16 EIM92199.1 - 1.3e-17 64.0 0.0 3e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIM92199.1 - 7.9e-10 38.6 0.0 6.7e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-CCCH PF00642.19 EIM92200.1 - 6.4e-18 63.9 24.4 4.7e-05 22.9 0.4 4.6 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 EIM92200.1 - 0.00014 21.6 4.2 0.00067 19.4 2.9 2.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIM92200.1 - 0.0032 17.1 0.1 0.0088 15.7 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 EIM92200.1 - 0.023 14.6 30.5 0.072 13.1 0.2 5.4 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type DUF1115 PF06544.7 EIM92200.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) UPF0047 PF01894.12 EIM92201.1 - 1.8e-42 143.8 0.1 2e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 EIM92202.1 - 1.5e-08 33.8 0.2 2.8e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM92202.1 - 9.9e-07 28.5 9.2 2.3e-06 27.4 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.7 EIM92202.1 - 9.3 6.7 6.6 0.54 10.6 0.7 1.8 2 0 0 2 2 2 0 SlyX TFIIA PF03153.8 EIM92203.1 - 0.73 9.6 21.6 0.97 9.2 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 EIM92203.1 - 1.3 8.2 21.4 1.6 7.8 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.12 EIM92203.1 - 2.7 7.7 16.2 1.3 8.8 8.2 2.2 1 1 2 3 3 3 0 DDHD domain RhoGEF PF00621.15 EIM92204.1 - 2.3e-14 53.6 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain MMR_HSR1 PF01926.18 EIM92205.1 - 1.2e-12 47.8 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM92205.1 - 3.7e-05 23.0 0.0 7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIM92205.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIM92205.1 - 0.01 15.6 1.4 0.38 10.5 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 EIM92205.1 - 0.086 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Pyr_redox PF00070.22 EIM92206.1 - 3e-13 49.9 0.1 1.7e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIM92206.1 - 9.7e-13 48.4 0.3 1.3e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIM92206.1 - 2.7e-06 27.5 0.4 0.0041 17.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM92206.1 - 1.8e-05 24.5 0.2 0.95 9.2 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EIM92206.1 - 0.0043 16.0 2.0 0.45 9.3 0.1 3.1 2 2 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIM92206.1 - 0.011 14.7 0.2 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EIM92206.1 - 0.019 14.0 0.2 1.8 7.5 0.0 2.3 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Methyltransf_11 PF08241.7 EIM92207.1 - 8.9e-14 51.7 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM92207.1 - 1.9e-12 47.2 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM92207.1 - 2e-10 41.2 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIM92207.1 - 3.6e-09 36.0 0.0 5.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIM92207.1 - 1.7e-08 34.7 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIM92207.1 - 2.1e-06 27.3 0.0 5.4e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIM92207.1 - 2.3e-06 27.9 0.0 3.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM92207.1 - 3.3e-05 23.9 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIM92207.1 - 0.00022 20.3 0.0 0.0048 15.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EIM92207.1 - 0.00081 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EIM92207.1 - 0.0015 16.9 0.0 0.0025 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EIM92207.1 - 0.0042 16.1 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EIM92207.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EIM92207.1 - 0.1 12.2 0.0 0.45 10.1 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase WD40 PF00400.27 EIM92208.1 - 1e-22 79.0 5.5 0.00017 21.3 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Homeobox PF00046.24 EIM92209.1 - 2.9e-10 39.6 0.1 6e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM92209.1 - 0.026 14.2 0.1 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 EIM92210.1 - 1.3e-15 56.7 0.1 3.1e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM92210.1 - 7.4e-05 22.3 0.3 0.00021 20.8 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF601 PF04642.7 EIM92210.1 - 1.9 7.7 11.3 0.4 10.0 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF601 F-box-like PF12937.2 EIM92211.1 - 9.5e-08 31.6 0.1 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM92211.1 - 0.011 15.3 0.3 0.27 10.8 0.1 2.8 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIM92211.1 - 0.052 13.3 0.4 0.56 9.9 0.1 2.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 EIM92211.1 - 0.067 13.2 0.3 11 6.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 EIM92211.1 - 0.15 12.2 0.8 4.3 7.7 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PB1 PF00564.19 EIM92212.1 - 1e-07 31.5 1.9 1.9e-07 30.6 0.0 2.5 3 0 0 3 3 3 1 PB1 domain KOG2701 PF09762.4 EIM92212.1 - 4.9 7.1 4.4 8 6.4 3.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Aldo_ket_red PF00248.16 EIM92213.1 - 2.6e-48 164.3 0.0 3e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AATase PF07247.7 EIM92215.1 - 0.014 13.9 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase TPT PF03151.11 EIM92216.1 - 1.7e-07 30.9 14.0 1.7e-07 30.9 9.7 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIM92216.1 - 7.3e-05 22.8 33.9 0.0016 18.4 7.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family COPI_assoc PF08507.5 EIM92216.1 - 0.00093 18.8 0.2 0.00093 18.8 0.2 3.3 2 1 1 3 3 3 1 COPI associated protein DUF2788 PF10981.3 EIM92216.1 - 6.1 6.7 10.2 0.44 10.3 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) O-FucT PF10250.4 EIM92217.1 - 7.3e-08 31.8 0.0 1.9e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase ApbA_C PF08546.6 EIM92218.1 - 9e-34 116.1 0.2 1.7e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIM92218.1 - 5.3e-22 77.8 0.6 2.1e-20 72.7 0.4 2.5 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF1741 PF08427.5 EIM92219.1 - 7.3e-40 136.9 3.3 4e-39 134.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1741) F-box-like PF12937.2 EIM92220.1 - 3.9e-08 32.8 1.1 1.1e-07 31.4 0.8 1.9 1 0 0 1 1 1 1 F-box-like GDC-P PF02347.11 EIM92221.1 - 8.6e-179 594.6 0.0 5.6e-167 555.7 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EIM92221.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIM92221.1 - 0.019 13.3 0.1 0.032 12.5 0.1 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SecE PF00584.15 EIM92222.1 - 9.2e-15 53.9 0.0 1e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.5 EIM92222.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) PPR_2 PF13041.1 EIM92223.1 - 6.7e-09 35.5 0.5 0.22 11.4 0.0 7.0 6 2 1 8 8 8 2 PPR repeat family PPR_3 PF13812.1 EIM92223.1 - 4.1e-07 29.7 1.2 6.1 7.3 0.0 7.7 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EIM92223.1 - 0.00048 19.9 1.6 14 5.9 0.1 5.4 6 0 0 6 6 6 2 PPR repeat Vps51 PF08700.6 EIM92224.1 - 1.9e-12 46.8 0.0 7.5e-12 44.9 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 EIM92224.1 - 0.03 14.0 1.7 0.098 12.3 0.0 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF1751 PF08551.5 EIM92225.1 - 1.2e-26 92.9 3.4 1.2e-26 92.9 2.4 1.9 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EIM92225.1 - 0.25 11.3 8.6 0.62 10.0 5.9 1.7 1 1 0 1 1 1 0 Rhomboid family Ribosomal_60s PF00428.14 EIM92225.1 - 4.9 7.6 8.1 13 6.2 5.6 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF1754 PF08555.5 EIM92226.1 - 1e-12 48.4 1.1 1e-12 48.4 0.8 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.1 EIM92226.1 - 0.0061 15.7 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) HTH_Tnp_IS630 PF01710.11 EIM92226.1 - 0.072 12.7 0.5 0.072 12.7 0.3 1.7 2 0 0 2 2 2 0 Transposase Peptidase_M3 PF01432.15 EIM92228.1 - 1.4e-129 433.1 0.0 1.8e-129 432.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EIM92228.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Effector protein Mating_C PF12737.2 EIM92229.1 - 2.4e-08 33.3 32.0 2.4e-08 33.3 22.2 1.8 1 1 0 1 1 1 1 C-terminal domain of homeodomain 1 Mating_N PF12731.2 EIM92229.1 - 1.2e-07 31.4 0.4 2.3e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 ORC6 PF05460.8 EIM92229.1 - 1.8 7.5 8.3 3.4 6.6 5.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Homeobox_KN PF05920.6 EIM92231.1 - 1.4e-05 24.6 0.0 4.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.2 EIM92231.1 - 2.5e-05 24.0 3.3 0.00012 21.8 0.5 2.4 1 1 1 2 2 2 2 Mating-type protein beta 1 Aldo_ket_red PF00248.16 EIM92234.1 - 0.0062 15.3 0.0 0.0063 15.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ParA PF10609.4 EIM92235.1 - 1.8e-32 111.0 0.1 3e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIM92235.1 - 1.4e-15 57.2 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIM92235.1 - 6.9e-07 29.3 0.0 2.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EIM92235.1 - 2.8e-06 26.6 0.0 1.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EIM92235.1 - 8.8e-06 24.9 0.4 0.00065 18.8 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_22 PF13401.1 EIM92235.1 - 0.061 13.4 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIM92235.1 - 0.081 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 EIM92235.1 - 0.09 12.3 0.2 8.3 5.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 EIM92235.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein Abhydrolase_6 PF12697.2 EIM92237.1 - 0.0037 17.1 0.1 0.0063 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.17 EIM92238.1 - 6.7e-12 44.8 0.0 3.9e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM92238.1 - 7.5e-09 35.4 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM92238.1 - 8.6e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIM92238.1 - 4e-05 23.3 0.0 8.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb6 PF01192.17 EIM92239.1 - 4.5e-22 77.5 0.3 5.3e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.12 EIM92240.1 - 1.5e-33 115.9 0.0 1.9e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.13 EIM92241.1 - 1.4e-36 125.8 0.1 2.2e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family EthD PF07110.6 EIM92242.1 - 1.3e-07 32.4 0.1 0.0021 18.9 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 EIM92242.1 - 0.001 19.3 0.0 0.56 10.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) ABM PF03992.11 EIM92242.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF2914 PF11141.3 EIM92242.1 - 0.12 11.9 1.5 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Myb_DNA-binding PF00249.26 EIM92243.1 - 3.1e-07 30.3 0.0 6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIM92243.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rep_fac_C PF08542.6 EIM92244.1 - 6.6e-22 77.2 0.0 1.4e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EIM92244.1 - 3e-12 46.8 0.0 5.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIM92244.1 - 4.8e-12 45.8 0.0 2.7e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EIM92244.1 - 3.4e-07 30.2 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EIM92244.1 - 4.5e-06 25.6 0.0 0.0034 16.1 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIM92244.1 - 6.8e-06 26.2 0.1 0.0055 16.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EIM92244.1 - 9.9e-06 25.6 0.0 0.00014 21.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIM92244.1 - 1.1e-05 24.5 0.0 3.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EIM92244.1 - 4.9e-05 22.9 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EIM92244.1 - 0.00012 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EIM92244.1 - 0.0011 18.4 0.1 0.24 10.8 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 EIM92244.1 - 0.0012 18.0 0.0 0.013 14.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EIM92244.1 - 0.002 17.8 0.1 0.016 14.8 0.0 2.1 1 1 1 2 2 2 1 NTPase DNA_pol3_delta PF06144.8 EIM92244.1 - 0.0021 17.6 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EIM92244.1 - 0.0021 17.7 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EIM92244.1 - 0.0059 15.4 0.1 0.024 13.4 0.0 1.9 2 1 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EIM92244.1 - 0.0067 16.5 0.2 0.18 12.0 0.1 2.8 2 1 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 EIM92244.1 - 0.028 13.8 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.1 EIM92244.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EIM92244.1 - 0.034 13.6 0.1 0.55 9.7 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 EIM92244.1 - 0.073 13.3 0.1 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIM92244.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.20 EIM92245.1 - 1.2e-27 96.6 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIM92245.1 - 4.9e-08 32.9 0.9 4.9e-08 32.9 0.6 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EIM92245.1 - 0.04 13.5 0.5 0.074 12.7 0.4 1.3 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 EIM92245.1 - 0.097 11.5 0.9 0.17 10.8 0.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 EIM92245.1 - 0.22 11.7 2.3 2.6 8.3 0.4 2.2 1 1 1 2 2 2 0 Spectrin repeat VHS PF00790.14 EIM92246.1 - 1.5e-26 92.7 0.0 3.3e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIM92246.1 - 3.5e-08 33.3 0.6 1.5e-07 31.3 0.4 2.1 1 0 0 1 1 1 1 GAT domain NARP1 PF12569.3 EIM92246.1 - 0.18 10.5 20.8 1.5 7.5 0.4 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MIF4G_like_2 PF09090.6 EIM92246.1 - 0.22 10.7 14.2 0.011 14.9 3.7 2.6 2 1 1 3 3 3 0 MIF4G like Pectate_lyase_3 PF12708.2 EIM92247.1 - 5.4e-83 278.5 26.5 2.3e-66 224.1 6.0 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIM92247.1 - 5.9e-07 28.8 1.2 0.016 14.6 0.3 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Utp11 PF03998.8 EIM92248.1 - 1.3e-62 211.8 16.8 1.6e-62 211.5 11.6 1.1 1 0 0 1 1 1 1 Utp11 protein PI-PLC-X PF00388.14 EIM92250.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF512 PF04459.7 EIM92250.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Sigma54_AID PF00309.15 EIM92250.1 - 0.12 11.8 0.2 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) EF-hand_6 PF13405.1 EIM92251.1 - 9.2e-10 37.5 3.6 1.7e-05 24.2 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EIM92251.1 - 2.4e-09 37.2 4.1 5e-06 26.5 2.9 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIM92251.1 - 2.1e-08 32.8 5.6 1.3e-05 24.1 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 EIM92251.1 - 0.0013 17.9 0.6 0.0013 17.9 0.5 2.5 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 EIM92251.1 - 0.096 12.7 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 EIM92251.1 - 0.13 11.8 5.6 0.24 11.0 0.0 3.4 2 1 2 4 4 4 0 EF-hand domain pair Amidohydro_4 PF13147.1 EIM92253.1 - 2.4e-25 90.1 0.1 4.5e-24 85.9 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIM92253.1 - 8.3e-25 88.1 0.0 4.4e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM92253.1 - 3.9e-12 45.7 1.1 8.7e-12 44.6 0.0 2.1 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM92253.1 - 3.1e-06 26.6 0.2 0.015 14.5 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.9 EIM92253.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Methyltransf_25 PF13649.1 EIM92254.1 - 0.00023 21.4 0.0 0.00051 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM92254.1 - 0.0077 15.9 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2 PF00096.21 EIM92255.1 - 1.8e-09 37.3 17.0 4.8e-05 23.4 1.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIM92255.1 - 0.00034 20.7 3.7 0.00034 20.7 2.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EIM92255.1 - 0.0018 18.4 0.6 0.0018 18.4 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIM92255.1 - 0.0027 17.8 0.4 0.0027 17.8 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIM92255.1 - 0.01 16.1 1.2 0.01 16.1 0.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3591 PF12157.3 EIM92256.1 - 2.2e-181 603.2 1.1 3.6e-181 602.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EIM92256.1 - 3.3e-05 23.4 2.7 6.5e-05 22.5 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle BCA_ABC_TP_C PF12399.3 EIM92256.1 - 0.05 13.2 0.4 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-CCHC PF00098.18 EIM92256.1 - 0.25 11.3 1.5 0.51 10.3 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PA28_beta PF02252.13 EIM92257.1 - 1.9e-46 157.2 0.5 4.4e-46 156.0 0.1 1.6 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EIM92257.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit WD40 PF00400.27 EIM92258.1 - 1.5e-24 84.8 14.0 1.5e-09 37.4 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIM92258.1 - 1.9e-17 62.9 0.0 4.3e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EIM92258.1 - 3e-05 23.8 0.2 0.0017 18.0 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A MAPEG PF01124.13 EIM92259.1 - 5.2e-17 61.6 0.0 6e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 MAPEG family Ion_trans PF00520.26 EIM92261.1 - 0.03 13.5 6.7 0.037 13.2 3.3 2.0 1 1 1 2 2 2 0 Ion transport protein CWC25 PF12542.3 EIM92262.1 - 5.1e-24 84.5 0.2 5.1e-24 84.5 0.1 4.2 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EIM92262.1 - 1.7e-12 47.1 13.1 1.7e-12 47.1 9.1 4.6 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR 3Beta_HSD PF01073.14 EIM92264.1 - 6.4e-12 44.7 0.0 2.8e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM92264.1 - 2.2e-10 40.8 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIM92264.1 - 3.3e-08 32.7 0.0 0.003 16.4 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 EIM92264.1 - 4.1e-07 29.6 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIM92264.1 - 0.015 14.6 0.0 0.026 13.7 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 EIM92264.1 - 0.056 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EIM92264.1 - 0.099 11.5 0.0 0.31 9.9 0.0 1.6 1 1 1 2 2 2 0 Male sterility protein TrkA_N PF02254.13 EIM92264.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 EIM92265.1 - 6.8e-50 169.7 27.8 6.8e-50 169.7 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM92265.1 - 2.1e-13 49.6 8.5 2.1e-13 49.6 5.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EIM92265.1 - 4.5e-10 38.5 23.1 8.7e-10 37.5 4.0 3.6 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EIM92265.1 - 4.4e-09 35.0 2.9 8.1e-09 34.2 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EIM92265.1 - 2.7e-07 29.4 17.7 0.00018 20.1 1.4 3.2 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EIM92265.1 - 3.1e-05 22.2 7.9 6.1e-05 21.3 5.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 EIM92265.1 - 0.011 15.5 0.1 0.011 15.5 0.1 3.2 3 1 1 4 4 4 0 MFS_1 like family HORMA PF02301.13 EIM92268.1 - 1.4e-23 83.5 0.1 1.9e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EIM92268.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 PX PF00787.19 EIM92269.1 - 2.8e-19 68.9 0.6 8.9e-19 67.3 0.4 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EIM92269.1 - 6.2e-09 35.4 8.8 0.00089 18.5 2.9 2.8 1 1 2 3 3 3 2 Vps5 C terminal like Lung_7-TM_R PF06814.8 EIM92270.1 - 2.4e-61 207.3 14.7 3e-61 206.9 10.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor RNA_pol_Rpb2_6 PF00562.23 EIM92272.1 - 3.3e-128 427.7 0.1 5.7e-128 426.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIM92272.1 - 8.9e-67 223.9 0.0 1.4e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIM92272.1 - 1.8e-48 164.4 0.1 4.3e-48 163.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIM92272.1 - 2.3e-29 101.4 0.0 5.2e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EIM92272.1 - 1.6e-26 91.8 0.6 4.4e-26 90.4 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIM92272.1 - 4.4e-24 84.0 0.1 1.1e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIM92272.1 - 8.7e-24 83.2 0.1 1.8e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Git3 PF11710.3 EIM92273.1 - 3e-09 36.7 4.7 6.5e-09 35.6 3.3 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EIM92273.1 - 4.1e-07 29.3 3.7 6.1e-07 28.8 2.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EIM92273.1 - 0.00064 19.4 0.1 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Fungal_trans PF04082.13 EIM92274.1 - 5.2e-20 71.4 0.7 9.3e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM92274.1 - 0.00017 21.3 9.0 0.00017 21.3 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fructosamin_kin PF03881.9 EIM92275.1 - 7.6e-65 218.7 0.0 9.3e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EIM92275.1 - 3.2e-09 36.8 0.0 7.7e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 EIM92276.1 - 1.9e-22 79.4 0.0 9.2e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EIM92276.1 - 0.044 13.5 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family MAPEG PF01124.13 EIM92277.1 - 4.7e-20 71.5 1.1 5.5e-20 71.2 0.7 1.0 1 0 0 1 1 1 1 MAPEG family DUF3667 PF12412.3 EIM92277.1 - 0.1 11.9 0.1 9.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) DUF2427 PF10348.4 EIM92278.1 - 0.04 13.4 0.2 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Glyco_transf_8 PF01501.15 EIM92279.1 - 7.7e-29 100.7 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIM92279.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative FAM178 PF14816.1 EIM92279.1 - 0.86 8.2 1.8 1.4 7.5 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Nop14 PF04147.7 EIM92280.1 - 0.066 11.1 3.4 0.077 10.9 2.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIM92280.1 - 6.6 4.6 8.2 10 4.0 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ANTH PF07651.11 EIM92282.1 - 2.8e-72 242.7 0.0 2.8e-72 242.7 0.0 3.1 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EIM92282.1 - 7.8e-62 207.7 7.5 7.8e-62 207.7 5.2 4.8 5 0 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 EIM92282.1 - 3.2e-06 26.9 1.5 2.5e-05 24.1 0.0 3.4 4 0 0 4 4 4 1 ENTH domain TcdB_N PF12918.2 EIM92282.1 - 0.0021 18.0 0.2 0.025 14.6 0.0 2.9 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain SURF1 PF02104.10 EIM92283.1 - 1.3e-56 191.7 0.0 1.6e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family DUF3508 PF12018.3 EIM92284.1 - 0.26 10.2 1.2 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) ATP-synt_B PF00430.13 EIM92286.1 - 0.014 15.2 1.3 0.014 15.2 0.9 3.5 2 1 0 3 3 3 0 ATP synthase B/B' CF(0) MFS_1 PF07690.11 EIM92287.1 - 3.8e-37 127.8 28.6 3.8e-37 127.8 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM92287.1 - 2.1e-09 36.4 26.5 2.3e-08 33.0 18.5 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF4179 PF13786.1 EIM92287.1 - 6 7.1 5.4 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Med19 PF10278.4 EIM92288.1 - 0.57 9.8 16.0 0.093 12.3 3.4 2.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF908 PF06012.7 EIM92288.1 - 5.7 6.1 11.1 0.029 13.6 1.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Med7 PF05983.6 EIM92289.1 - 7.3e-29 100.6 0.3 8.8e-29 100.3 0.2 1.1 1 0 0 1 1 1 1 MED7 protein U3_assoc_6 PF08640.6 EIM92289.1 - 0.0056 16.4 0.6 2.1 8.1 0.0 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 AphA_like PF14557.1 EIM92289.1 - 0.024 14.2 0.7 0.041 13.4 0.5 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator FerA PF08165.6 EIM92289.1 - 0.064 12.9 0.6 0.12 12.0 0.4 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain Pal1 PF08316.6 EIM92293.1 - 0.013 15.8 0.0 0.013 15.8 0.0 4.9 3 2 0 3 3 3 0 Pal1 cell morphology protein GARS_A PF01071.14 EIM92294.1 - 4.8e-80 267.6 0.0 7.5e-80 267.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EIM92294.1 - 1.2e-33 115.5 0.0 3.3e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EIM92294.1 - 1.8e-33 115.6 0.0 5.6e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EIM92294.1 - 3.8e-28 97.4 0.4 8.9e-28 96.3 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EIM92294.1 - 2.4e-18 66.1 1.9 1.2e-16 60.6 0.5 3.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EIM92294.1 - 9.5e-08 31.9 0.0 3.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIM92294.1 - 2.7e-07 29.6 0.0 5.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EIM92294.1 - 5.2e-05 22.6 0.1 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EIM92294.1 - 0.0027 17.5 0.2 0.0065 16.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Shisa PF13908.1 EIM92295.1 - 5.6 7.0 5.8 6 7.0 4.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NAD_Gly3P_dh_C PF07479.9 EIM92296.1 - 4.9e-46 156.1 0.1 6.8e-46 155.6 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIM92296.1 - 1.4e-33 115.8 0.0 2.2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EIM92296.1 - 3.3e-10 39.6 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIM92296.1 - 1.8e-06 28.2 0.0 5.2e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIM92296.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 EIM92296.1 - 0.012 15.9 0.0 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PDH PF02153.12 EIM92296.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase SNARE PF05739.14 EIM92297.1 - 6.2e-14 51.4 0.5 6.2e-14 51.4 0.3 2.9 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIM92297.1 - 1.7e-12 47.4 4.8 1.7e-12 47.4 3.3 2.9 3 1 0 3 3 2 1 Syntaxin HrpB7 PF09486.5 EIM92297.1 - 0.0031 17.4 3.9 0.0038 17.1 0.4 2.4 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.4 EIM92297.1 - 0.0061 15.5 5.7 0.59 9.0 2.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EIM92297.1 - 0.021 14.7 1.9 0.64 9.9 0.0 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 EIM92297.1 - 0.041 13.1 8.4 0.81 8.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Osmo_CC PF08946.5 EIM92297.1 - 0.047 13.7 4.3 0.35 10.9 0.2 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil zf-C4H2 PF10146.4 EIM92297.1 - 0.054 13.5 2.7 0.9 9.5 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF3818 PF12825.2 EIM92297.1 - 0.45 9.1 6.5 5.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) NPV_P10 PF05531.7 EIM92297.1 - 0.56 10.4 11.9 0.19 11.9 2.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 EIM92297.1 - 0.71 10.2 7.1 1.3 9.4 0.1 3.1 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.7 EIM92297.1 - 0.98 9.2 8.8 1.9 8.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 EIM92297.1 - 1.1 9.5 5.8 1.5 9.1 0.2 2.7 3 1 0 3 3 2 0 Spectrin repeat FliD_N PF02465.13 EIM92297.1 - 2.2 8.7 10.6 1.2 9.5 0.1 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF948 PF06103.6 EIM92297.1 - 3.2 7.6 8.7 5.8 6.8 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 EIM92297.1 - 3.5 7.1 10.7 0.059 12.9 0.5 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 EIM92297.1 - 6.7 6.2 10.0 4.1 6.9 0.4 2.3 2 0 0 2 2 2 0 IncA protein RRM_1 PF00076.17 EIM92298.1 - 7.3e-10 38.3 0.0 2.1e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM92298.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_polI_A34 PF08208.6 EIM92299.1 - 0.069 12.8 1.2 0.13 11.9 0.7 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AMP-binding PF00501.23 EIM92300.1 - 3.9e-85 285.7 0.0 4.9e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIM92300.1 - 6.8e-17 62.1 0.3 6.8e-17 62.1 0.2 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain MRP-S25 PF13741.1 EIM92301.1 - 3.5e-46 157.5 1.4 1.6e-44 152.1 0.9 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 YlbE PF14003.1 EIM92301.1 - 0.062 13.3 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 YlbE-like protein PCI PF01399.22 EIM92302.1 - 1.8e-17 63.5 0.0 1.1e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_20 PF14561.1 EIM92302.1 - 0.044 13.8 1.9 3.8 7.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_27 PF13463.1 EIM92302.1 - 0.07 13.4 0.4 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain F-box-like PF12937.2 EIM92303.1 - 0.0014 18.3 0.0 0.027 14.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like Drc1-Sld2 PF11719.3 EIM92305.1 - 5.4e-10 38.9 5.8 5.4e-10 38.9 4.0 2.9 2 2 0 2 2 2 1 DNA replication and checkpoint protein Abhydrolase_6 PF12697.2 EIM92308.1 - 3.7e-25 89.1 0.1 4.5e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM92308.1 - 2.2e-11 43.6 0.0 2e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM92308.1 - 6.2e-10 39.0 0.0 1.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EIM92308.1 - 0.00088 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EIM92308.1 - 0.0012 18.1 0.0 0.0038 16.5 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EIM92308.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EIM92308.1 - 0.079 12.8 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein Abhydrolase_2 PF02230.11 EIM92308.1 - 0.14 11.5 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase zf-met PF12874.2 EIM92309.1 - 1.5e-06 28.1 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EIM92309.1 - 0.035 13.3 0.6 0.062 12.5 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like ProQ PF04352.8 EIM92309.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 ProQ/FINO family S1 PF00575.18 EIM92310.1 - 3.9e-58 193.4 20.9 5.8e-13 48.7 0.1 10.5 10 0 0 10 10 10 8 S1 RNA binding domain TPR_12 PF13424.1 EIM92310.1 - 3.4e-06 26.9 2.1 0.2 11.6 0.0 4.6 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIM92310.1 - 6.8e-05 23.1 0.0 1.5 9.1 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM92310.1 - 9.7e-05 22.6 0.0 9.4 7.1 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat EXOSC1 PF10447.4 EIM92310.1 - 0.013 15.4 1.3 0.78 9.7 0.0 4.1 4 0 0 4 4 4 0 Exosome component EXOSC1/CSL4 Suf PF05843.9 EIM92310.1 - 0.017 14.8 10.2 0.1 12.3 0.1 3.6 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EIM92310.1 - 0.023 15.3 0.0 2.2 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 EIM92310.1 - 0.34 11.6 0.0 0.78 10.4 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat Kelch_3 PF13415.1 EIM92311.1 - 3.5e-30 103.4 16.1 4.8e-08 32.9 0.0 6.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EIM92311.1 - 6.1e-25 86.7 8.8 0.00016 21.5 0.0 6.4 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 EIM92311.1 - 1.3e-23 82.4 19.2 0.00015 21.4 0.0 6.8 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EIM92311.1 - 7.6e-21 73.4 1.6 5.2e-05 22.7 0.0 6.4 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EIM92311.1 - 4.7e-20 70.8 5.8 0.00067 19.7 1.3 6.3 3 2 2 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EIM92311.1 - 4.5e-16 57.8 3.6 0.001 18.7 0.9 6.1 5 1 0 5 5 5 5 Kelch motif RAG2 PF03089.9 EIM92311.1 - 0.11 11.2 2.0 8.9 4.9 0.0 3.8 4 1 1 5 5 5 0 Recombination activating protein 2 zf-C2H2_4 PF13894.1 EIM92312.1 - 0.005 17.0 0.5 0.0074 16.5 0.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIM92312.1 - 0.017 15.3 1.2 0.023 15.0 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIM92312.1 - 0.027 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Lgl_C PF08596.5 EIM92314.1 - 9e-35 119.8 0.0 3.8e-34 117.8 0.0 2.0 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EIM92314.1 - 3.6e-06 26.6 2.2 0.042 13.7 0.3 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2358 PF10184.4 EIM92315.1 - 9.6e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 EIM92315.1 - 0.014 15.7 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF4092 PF13322.1 EIM92315.1 - 0.039 13.6 0.0 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4092) V-SNARE_C PF12352.3 EIM92316.1 - 5.6e-17 61.5 8.1 7e-17 61.2 0.6 3.4 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus TPR_MLP1_2 PF07926.7 EIM92316.1 - 0.00064 19.4 2.3 0.0011 18.7 1.6 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF148 PF02520.12 EIM92316.1 - 0.0034 17.1 1.6 0.022 14.5 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF148 AAA_13 PF13166.1 EIM92316.1 - 0.008 14.7 0.5 0.019 13.4 0.2 1.5 1 1 0 1 1 1 1 AAA domain Filament PF00038.16 EIM92316.1 - 0.011 15.2 4.4 0.032 13.7 2.6 1.9 1 1 1 2 2 2 0 Intermediate filament protein Sec20 PF03908.8 EIM92316.1 - 0.011 15.3 0.6 0.047 13.3 0.0 2.2 2 1 0 2 2 2 0 Sec20 Tropomyosin_1 PF12718.2 EIM92316.1 - 0.022 14.6 1.8 0.029 14.2 0.4 1.8 1 1 1 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.17 EIM92316.1 - 0.031 14.2 0.6 0.83 9.7 0.0 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EIM92316.1 - 0.036 13.6 1.6 0.1 12.1 1.3 1.6 1 1 0 1 1 1 0 GrpE Laminin_I PF06008.9 EIM92316.1 - 0.041 13.2 2.5 0.096 11.9 0.9 1.9 1 1 2 3 3 3 0 Laminin Domain I GAS PF13851.1 EIM92316.1 - 0.054 12.6 1.3 0.095 11.8 0.8 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.3 EIM92316.1 - 0.056 13.1 0.9 7.3 6.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.14 EIM92316.1 - 0.059 11.2 0.5 0.074 10.8 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EIM92316.1 - 0.061 13.1 2.2 4.3 7.1 0.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EIM92316.1 - 0.077 12.5 1.1 0.16 11.4 0.6 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EIM92316.1 - 0.14 12.4 5.5 0.53 10.5 0.9 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EIM92316.1 - 0.16 11.5 1.4 0.39 10.3 0.4 1.9 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1110 PF06533.7 EIM92316.1 - 0.17 11.6 1.5 1.4 8.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) IncA PF04156.9 EIM92316.1 - 0.42 10.1 4.1 1.5 8.3 2.7 2.1 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EIM92316.1 - 0.42 10.3 5.0 0.46 10.2 1.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 EIM92316.1 - 0.52 10.1 5.6 2.2 8.1 0.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEP-utilisers_N PF05524.8 EIM92316.1 - 1.4 8.7 6.1 8.6 6.1 2.0 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal FUSC PF04632.7 EIM92316.1 - 3.9 5.7 7.3 24 3.1 4.6 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family TatD_DNase PF01026.16 EIM92317.1 - 3.2e-17 62.5 0.0 1.1e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Met_10 PF02475.11 EIM92318.1 - 2.2e-69 233.1 0.0 2.5e-68 229.6 0.0 2.0 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EIM92318.1 - 1.3e-05 25.2 0.0 0.00076 19.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM92318.1 - 0.001 19.6 0.0 0.024 15.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 EIM92318.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 EIM92318.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Mito_carr PF00153.22 EIM92319.1 - 7.1e-71 234.0 1.1 4.7e-25 87.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EIM92319.1 - 2.4e-14 51.4 4.8 6.5e-06 25.0 0.1 6.3 7 0 0 7 7 7 2 EF hand EF-hand_6 PF13405.1 EIM92319.1 - 9.5e-14 49.9 3.8 0.00019 21.0 0.1 6.1 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EIM92319.1 - 4e-13 49.3 5.6 0.00062 19.8 0.1 4.9 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.1 EIM92319.1 - 5.1e-11 42.0 0.9 0.0019 17.7 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EIM92319.1 - 1.2e-07 30.7 3.6 0.00016 20.8 0.1 4.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EIM92319.1 - 0.00064 19.5 0.2 0.43 10.5 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain MoaC PF01967.16 EIM92320.1 - 3.4e-42 143.3 0.1 4.7e-37 126.7 0.1 2.4 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 EIM92320.1 - 7e-34 116.2 0.4 2.1e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EIM92320.1 - 8.3e-23 81.3 0.0 1.9e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EIM92320.1 - 3.6e-07 30.3 0.0 7.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EIM92320.1 - 6e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Acetyltransf_7 PF13508.1 EIM92321.1 - 2e-07 31.0 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIM92321.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIM92321.1 - 6.5e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIM92321.1 - 4.3e-06 26.8 0.0 7.9e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIM92321.1 - 0.0032 17.3 0.1 0.0085 15.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIM92321.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF953 PF06110.6 EIM92322.1 - 3.7e-19 68.3 0.0 4.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EIM92322.1 - 0.01 15.4 0.0 0.025 14.2 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin NIPSNAP PF07978.8 EIM92323.1 - 1.9e-29 101.6 3.5 7.6e-24 83.6 0.2 2.1 2 0 0 2 2 2 2 NIPSNAP DUF718 PF05336.8 EIM92323.1 - 0.042 13.6 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF718) O-FucT PF10250.4 EIM92324.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase APG6 PF04111.7 EIM92325.1 - 0.0014 17.7 12.5 0.0014 17.7 8.7 11.2 5 4 6 12 12 12 7 Autophagy protein Apg6 MFS_1 PF07690.11 EIM92326.1 - 1.7e-44 151.9 36.2 1.6e-30 106.0 5.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM92326.1 - 0.064 13.0 11.3 0.57 10.0 0.0 4.3 2 1 2 4 4 4 0 MFS_1 like family Fapy_DNA_glyco PF01149.19 EIM92327.1 - 1.4e-25 89.8 0.1 2.3e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EIM92327.1 - 2e-19 69.1 0.0 6.5e-19 67.4 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EIM92327.1 - 0.0021 16.7 0.0 0.006 15.1 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 EIM92327.1 - 0.0067 16.8 0.0 0.041 14.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S13/S18 Utp12 PF04003.7 EIM92328.1 - 4.3e-11 42.7 0.3 2.1e-10 40.4 0.2 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EIM92328.1 - 2.1e-06 27.3 6.3 0.041 13.7 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.20 EIM92329.1 - 4.3e-75 252.2 0.0 6.1e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92329.1 - 8.3e-36 123.3 0.3 1.7e-35 122.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92329.1 - 0.001 18.1 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92329.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.5 EIM92329.1 - 1.1 7.4 27.0 1.5 6.9 18.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DARPP-32 PF05395.7 EIM92331.1 - 9.3 6.3 12.8 0.74 9.9 2.2 2.5 2 1 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 WD40 PF00400.27 EIM92332.1 - 1.8e-60 198.7 10.5 4.3e-11 42.2 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EIM92332.1 - 2e-33 115.4 0.0 5.6e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EIM92332.1 - 0.00011 20.5 1.3 0.62 8.1 0.1 3.7 1 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EIM92332.1 - 0.00051 19.8 0.0 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIM92332.1 - 0.0019 16.5 0.0 0.0033 15.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain LisH PF08513.6 EIM92332.1 - 0.0037 16.9 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 LisH ADH_N PF08240.7 EIM92333.1 - 3.5e-29 100.7 0.7 6.8e-29 99.8 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM92333.1 - 8.9e-14 51.1 0.0 1.3e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EIM92333.1 - 9.5e-05 22.9 0.0 0.00029 21.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EIM92333.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EIM92333.1 - 0.043 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIM92333.1 - 0.077 13.4 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF221 PF02714.10 EIM92334.1 - 3.8e-12 45.7 11.5 6.1e-12 45.0 7.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EIM92334.1 - 1.7e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein RSN1_TM PF13967.1 EIM92334.1 - 0.0004 19.9 3.9 0.00042 19.9 0.3 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIM92334.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Metallophos PF00149.23 EIM92336.1 - 7.4e-12 45.0 3.3 2.2e-11 43.5 2.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM92336.1 - 0.00064 19.5 0.3 0.0036 17.1 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.2 EIM92337.1 - 4.3e-05 23.1 2.6 0.00031 20.4 1.8 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM92337.1 - 0.037 13.6 1.4 0.3 10.7 1.0 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF4061 PF13270.1 EIM92338.1 - 0.15 12.1 0.1 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) NUDE_C PF04880.8 EIM92341.1 - 3.8e-09 37.1 11.3 3.8e-09 37.1 7.8 5.9 3 2 3 6 6 3 1 NUDE protein, C-terminal conserved region Rab5-bind PF09311.6 EIM92341.1 - 0.00055 19.8 13.2 0.00055 19.8 9.1 2.4 2 0 0 2 2 2 1 Rabaptin-like protein GAS PF13851.1 EIM92341.1 - 0.45 9.6 27.6 12 5.0 19.0 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3287 PF11690.3 EIM92341.1 - 0.65 10.0 12.9 2.4 8.2 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) TPR_MLP1_2 PF07926.7 EIM92341.1 - 1 9.1 27.7 1.2 8.8 5.1 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EIM92341.1 - 1.3 8.8 28.9 0.044 13.6 4.3 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EIM92341.1 - 1.6 8.6 35.4 0.13 12.1 16.9 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 EIM92341.1 - 1.9 7.9 32.0 0.046 13.2 10.2 2.7 2 1 1 3 3 3 0 Ezrin/radixin/moesin family IncA PF04156.9 EIM92341.1 - 1.9 8.0 33.4 0.28 10.7 11.2 2.5 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 EIM92341.1 - 2.5 8.0 8.3 0.96 9.3 0.6 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 EIM92341.1 - 4 7.1 29.5 7.5 6.3 3.7 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EIM92341.1 - 4.2 6.3 29.5 0.21 10.5 12.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 EXOSC1 PF10447.4 EIM92342.1 - 1.1e-20 73.3 0.0 2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Malic_M PF03949.10 EIM92343.1 - 2e-81 273.3 0.0 2.5e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIM92343.1 - 5.7e-65 218.2 0.0 9.1e-65 217.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GST_N_2 PF13409.1 EIM92344.1 - 7e-24 83.6 0.0 1.4e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIM92344.1 - 4.2e-14 52.1 0.0 1.3e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIM92344.1 - 5.5e-09 35.8 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIM92344.1 - 7.5e-06 26.0 0.0 8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIM92344.1 - 4.5e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M22 PF00814.20 EIM92345.1 - 3.6e-82 275.8 0.0 4.2e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Glyco_transf_8 PF01501.15 EIM92346.1 - 1.1e-32 113.4 0.0 2.6e-32 112.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIM92346.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DAO PF01266.19 EIM92347.1 - 1.7e-48 165.3 0.3 2.1e-48 165.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM92347.1 - 3.5e-06 26.9 0.9 9.9e-06 25.4 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIM92347.1 - 0.0058 16.7 0.1 2.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM92347.1 - 0.017 14.9 0.6 0.65 9.7 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIM92347.1 - 0.026 13.3 0.2 0.031 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EIM92347.1 - 0.038 12.8 0.2 0.076 11.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EIM92347.1 - 0.047 12.7 0.2 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EIM92347.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S28e PF01200.13 EIM92348.1 - 7.2e-34 115.3 2.2 7.7e-34 115.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PIP5K PF01504.13 EIM92349.1 - 2.5e-65 220.0 0.0 4.5e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EIM92349.1 - 8.9e-26 90.5 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EIM92349.1 - 1.5e-16 60.0 12.0 1.5e-16 60.0 8.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 EIM92349.1 - 3.4 7.6 11.5 0.53 10.1 4.8 1.9 2 0 0 2 2 2 0 IBR domain PCI PF01399.22 EIM92350.1 - 2.1e-20 72.9 1.1 7.2e-20 71.2 0.6 2.1 1 1 1 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EIM92350.1 - 3e-10 40.0 0.2 7.3e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 EIM92350.1 - 0.0095 15.6 0.1 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 FeoC like transcriptional regulator MRP-L28 PF09812.4 EIM92351.1 - 7.9e-11 42.0 10.6 3.4e-10 39.9 3.0 2.4 2 1 1 3 3 3 2 Mitochondrial ribosomal protein L28 DUF72 PF01904.13 EIM92351.1 - 0.019 14.7 0.4 0.024 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 Sec2p PF06428.6 EIM92351.1 - 0.093 12.5 1.6 0.15 11.9 1.1 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Nop25 PF09805.4 EIM92351.1 - 0.33 11.0 6.5 0.48 10.4 4.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PVL_ORF50 PF07768.6 EIM92351.1 - 0.36 10.8 6.5 0.42 10.6 3.8 1.6 1 1 0 1 1 1 0 PVL ORF-50-like family BEX PF04538.7 EIM92351.1 - 0.61 10.3 5.1 1.8 8.8 3.5 1.8 1 1 0 1 1 1 0 Brain expressed X-linked like family Rsm22 PF09243.5 EIM92352.1 - 8.7e-45 152.8 0.0 2.1e-24 86.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.24 EIM92353.1 - 5.1e-27 94.6 0.0 7.5e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIM92353.1 - 6.8e-13 48.5 0.4 1.2e-12 47.7 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein dsrm PF00035.20 EIM92354.1 - 9.9e-07 29.2 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 EIM92355.1 - 7.9e-11 42.3 0.0 9.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif WD40 PF00400.27 EIM92356.1 - 5.7e-55 181.3 21.3 3.8e-09 36.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIM92356.1 - 0.00015 21.5 0.0 0.099 12.3 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Tropomyosin PF00261.15 EIM92357.1 - 8.3e-05 21.7 41.3 8.3e-05 21.7 28.6 4.9 1 1 3 4 4 4 2 Tropomyosin Myosin_tail_1 PF01576.14 EIM92357.1 - 0.0011 16.7 23.8 0.0011 16.7 16.5 4.3 1 1 3 4 4 4 1 Myosin tail IncA PF04156.9 EIM92357.1 - 0.0014 18.2 113.7 1.7 8.2 19.1 6.1 1 1 5 6 6 6 3 IncA protein Reo_sigmaC PF04582.7 EIM92357.1 - 0.0046 16.1 56.7 0.053 12.6 1.2 5.4 2 1 4 6 6 6 5 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIM92357.1 - 0.0096 14.4 64.4 0.094 11.1 11.3 3.2 1 1 3 4 4 4 4 AAA domain STAT_alpha PF01017.15 EIM92357.1 - 0.011 15.4 10.4 0.011 15.4 7.2 5.7 1 1 3 5 5 5 0 STAT protein, all-alpha domain ATG16 PF08614.6 EIM92357.1 - 0.029 14.2 94.7 0.03 14.1 5.1 6.5 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EIM92357.1 - 0.056 13.2 92.6 0.027 14.3 21.6 6.4 1 1 5 6 6 6 0 Tropomyosin like bZIP_1 PF00170.16 EIM92357.1 - 0.1 12.5 0.0 0.1 12.5 0.0 9.1 6 2 6 12 12 12 0 bZIP transcription factor DUF869 PF05911.6 EIM92357.1 - 0.11 10.7 76.8 2.1 6.4 4.4 4.4 1 1 0 3 3 3 0 Plant protein of unknown function (DUF869) DUF812 PF05667.6 EIM92357.1 - 0.94 7.9 79.7 0.016 13.7 24.8 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Filament PF00038.16 EIM92357.1 - 1.1 8.6 87.8 1.4 8.3 4.0 6.5 1 1 3 5 5 5 0 Intermediate filament protein Spc7 PF08317.6 EIM92357.1 - 1.2 7.6 82.0 0.8 8.2 11.1 5.5 1 1 4 5 5 5 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EIM92357.1 - 1.7 8.5 101.3 1.2 9.0 13.1 8.3 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EIM92357.1 - 2.2 8.1 91.6 0.025 14.4 12.7 7.3 1 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EIM92357.1 - 5.9 6.6 50.4 0.038 13.7 1.2 6.9 1 1 7 9 9 9 0 Protein of unknown function (DUF1664) DUF690 PF05108.8 EIM92359.1 - 0.027 12.8 0.1 0.038 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Hexapep PF00132.19 EIM92360.1 - 5.3e-10 38.3 18.8 0.0025 17.2 0.5 4.5 3 2 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIM92360.1 - 0.062 12.8 13.9 0.049 13.2 3.7 3.0 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF2404 PF10296.4 EIM92361.1 - 9.4e-29 99.3 0.1 1.7e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EIM92361.1 - 0.0017 18.5 0.0 0.007 16.5 0.0 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 EIM92361.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Phage_GPL PF05926.6 EIM92363.1 - 0.15 11.9 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) DUF2414 PF10309.4 EIM92364.1 - 4.1e-09 35.9 0.0 6.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EIM92364.1 - 4.1e-06 26.6 0.0 6.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain DUF837 PF05769.6 EIM92365.1 - 4.4e-06 26.3 6.3 4.4e-06 26.3 4.3 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF837) NYD-SP28_assoc PF14775.1 EIM92365.1 - 0.031 13.9 6.2 0.51 10.0 1.8 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain DALR_1 PF05746.10 EIM92365.1 - 0.054 13.4 0.3 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 DALR anticodon binding domain Clathrin_lg_ch PF01086.12 EIM92365.1 - 0.29 11.0 6.1 0.37 10.6 0.1 2.5 2 0 0 2 2 2 0 Clathrin light chain PaaX_C PF08223.6 EIM92365.1 - 0.47 10.1 4.1 0.29 10.8 0.2 2.4 2 1 0 2 2 2 0 PaaX-like protein C-terminal domain bZIP_1 PF00170.16 EIM92365.1 - 3.2 7.7 7.1 17 5.4 1.9 2.4 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EIM92365.1 - 8.6 6.2 9.4 4.7 7.1 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.2 EIM92366.1 - 5.7e-08 32.3 2.1 1.6e-07 30.8 0.6 2.5 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIM92367.1 - 5.4e-06 26.0 1.0 2.5e-05 23.9 0.7 2.2 1 0 0 1 1 1 1 F-box-like Sporozoite_P67 PF05642.6 EIM92369.1 - 3.5 5.3 8.1 5.9 4.6 5.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DSHCT PF08148.7 EIM92370.1 - 3.4e-61 205.6 0.3 6e-61 204.8 0.2 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIM92370.1 - 9.3e-22 77.3 0.3 2.4e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EIM92370.1 - 5.8e-11 42.0 0.1 8.7e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EIM92370.1 - 5.7e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM92370.1 - 0.026 14.3 0.1 0.2 11.4 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ferritin_2 PF13668.1 EIM92371.1 - 1.5e-14 54.1 0.1 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ist1 PF03398.9 EIM92372.1 - 1e-57 194.1 0.9 1.4e-57 193.7 0.6 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ADK_lid PF05191.9 EIM92372.1 - 0.11 12.1 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid RasGEF PF00617.14 EIM92373.1 - 1.3e-35 122.8 0.0 2e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain SH3_1 PF00018.23 EIM92373.1 - 3.2e-16 58.4 0.2 8.5e-16 57.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.15 EIM92373.1 - 1.1e-15 57.6 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EIM92373.1 - 1.8e-11 43.4 0.2 5.9e-11 41.7 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIM92373.1 - 4.8e-11 41.9 0.0 1.1e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ras PF00071.17 EIM92374.1 - 9.5e-60 200.6 0.1 1.1e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM92374.1 - 2.6e-19 69.8 0.0 3.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIM92374.1 - 1.3e-13 50.5 0.1 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIM92374.1 - 3.1e-06 26.7 0.0 6.1e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIM92374.1 - 7.4e-06 25.2 0.0 8.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIM92374.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIM92374.1 - 0.038 13.9 0.2 0.13 12.2 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EIM92374.1 - 0.039 13.1 0.1 0.14 11.3 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF258 DUF385 PF04075.9 EIM92374.1 - 0.047 13.6 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF385) AAA_22 PF13401.1 EIM92374.1 - 0.048 13.8 0.0 0.38 10.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain TCP PF03634.8 EIM92374.1 - 0.12 12.7 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor Response_reg PF00072.19 EIM92374.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain G-alpha PF00503.15 EIM92374.1 - 0.16 10.6 0.4 7.1 5.1 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit PP2C PF00481.16 EIM92375.1 - 2.5e-16 59.8 0.0 7.2e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIM92375.1 - 3.3e-10 39.7 0.0 7.3e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C HTH_Tnp_Mu_1 PF02316.11 EIM92375.1 - 0.083 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain TipAS PF07739.8 EIM92375.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain MbeB_N PF04837.7 EIM92375.1 - 0.2 11.7 0.1 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region polyprenyl_synt PF00348.12 EIM92377.1 - 5.4e-48 163.1 0.0 2.6e-44 151.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Calreticulin PF00262.13 EIM92379.1 - 1.5e-148 494.3 7.4 2e-148 493.9 5.2 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.22 EIM92380.1 - 1.1e-42 145.6 0.0 1.7e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIM92380.1 - 2.2e-26 91.7 0.0 4.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIM92380.1 - 7.6e-21 73.7 0.0 1.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIM92380.1 - 3.7e-11 42.9 0.0 8.5e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM92380.1 - 1.6e-07 31.2 0.1 3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIM92380.1 - 4.6e-07 30.3 0.1 9.8e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 EIM92380.1 - 7e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.18 EIM92380.1 - 0.00019 21.2 0.3 0.12 12.2 0.2 2.5 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 EIM92380.1 - 0.0015 17.7 0.1 0.0042 16.3 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIM92380.1 - 0.0055 16.1 0.1 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 Ras family Prefoldin_2 PF01920.15 EIM92381.1 - 3.2e-15 55.7 6.5 4e-15 55.4 4.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 EIM92381.1 - 0.00086 19.1 1.2 0.00086 19.1 0.9 2.1 2 0 0 2 2 2 1 Tropomyosin like DUF3391 PF11871.3 EIM92381.1 - 0.058 13.5 0.5 0.094 12.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Lge1 PF11488.3 EIM92381.1 - 0.087 13.0 4.9 4.5 7.5 0.9 2.4 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 FliD_C PF07195.7 EIM92381.1 - 0.18 11.0 5.4 3.7 6.7 3.7 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF948 PF06103.6 EIM92381.1 - 2.7 7.9 5.0 2 8.3 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 EIM92381.1 - 2.7 7.6 8.9 0.9 9.1 0.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit TPR_11 PF13414.1 EIM92382.1 - 3.9e-20 71.2 9.1 5e-16 58.1 4.6 4.2 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EIM92382.1 - 9.9e-12 43.9 15.5 0.00048 19.6 0.5 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIM92382.1 - 9e-09 34.5 13.7 0.00016 21.3 0.6 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIM92382.1 - 1.9e-07 30.7 2.2 0.0034 17.4 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIM92382.1 - 4.8e-06 27.0 5.6 0.02 15.5 0.8 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIM92382.1 - 1.5e-05 24.4 6.6 0.52 10.2 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIM92382.1 - 0.0031 17.3 7.6 0.079 12.8 1.7 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIM92382.1 - 0.017 15.6 3.6 0.2 12.4 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIM92382.1 - 0.27 11.7 3.4 10 6.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EIM92382.1 - 0.41 10.5 6.6 37 4.3 0.0 4.3 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 EIM92382.1 - 1.9 8.9 7.6 2.3 8.6 0.8 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Chitin_bind_3 PF03067.10 EIM92384.1 - 0.001 19.3 0.1 0.0019 18.4 0.1 1.6 1 1 0 1 1 1 1 Chitin binding domain ADH_zinc_N PF00107.21 EIM92386.1 - 2.1e-31 108.1 0.1 3.7e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM92386.1 - 7.5e-13 49.4 0.4 3.6e-12 47.2 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIM92386.1 - 6.4e-06 25.8 0.0 0.00019 21.1 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 EIM92386.1 - 0.00028 20.6 0.0 0.0049 16.5 0.0 2.3 2 0 0 2 2 2 1 SIS domain TrkA_N PF02254.13 EIM92386.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RabGAP-TBC PF00566.13 EIM92387.1 - 1.5e-46 158.5 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ING PF12998.2 EIM92389.1 - 1.8e-13 50.6 0.6 2.9e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIM92389.1 - 4.2e-06 26.3 8.9 6.4e-06 25.7 6.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIM92389.1 - 0.029 14.5 1.6 0.057 13.5 1.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fip1 PF05182.8 EIM92390.1 - 4.8e-18 64.1 1.0 7.5e-18 63.5 0.7 1.3 1 0 0 1 1 1 1 Fip1 motif DUF2431 PF10354.4 EIM92391.1 - 2.1e-39 135.1 0.0 5.6e-37 127.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) DUF3126 PF11324.3 EIM92391.1 - 0.069 12.8 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) WD40 PF00400.27 EIM92392.1 - 9.8e-40 133.0 9.4 1.7e-10 40.3 0.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIM92392.1 - 3.3e-25 87.7 0.1 7.8e-25 86.5 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 EIM92392.1 - 0.072 11.8 0.0 1.1 7.9 0.0 2.2 1 1 0 1 1 1 0 Nup133 N terminal like ATP-synt_E PF05680.7 EIM92393.1 - 7.4e-19 67.4 0.1 7.7e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain Caudo_TAP PF02413.12 EIM92393.1 - 0.024 14.7 0.1 0.025 14.7 0.1 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein GFA PF04828.9 EIM92394.1 - 1.9e-10 40.5 4.3 3.9e-10 39.5 3.0 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-BED PF02892.10 EIM92394.1 - 0.0088 15.7 0.8 0.0088 15.7 0.6 1.9 2 0 0 2 2 2 1 BED zinc finger DUF1573 PF07610.6 EIM92394.1 - 0.45 10.1 0.1 0.45 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1573) Zn_ribbon_recom PF13408.1 EIM92394.1 - 1.5 9.1 9.1 2.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Dopey_N PF04118.9 EIM92396.1 - 1.3e-111 372.3 0.4 3.4e-111 370.9 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal EF-hand_7 PF13499.1 EIM92397.1 - 1.7e-08 34.4 1.7 1.8e-08 34.3 0.3 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EIM92397.1 - 1.2e-07 30.9 0.1 0.00061 19.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EIM92397.1 - 0.0006 18.9 0.8 0.044 13.0 0.1 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 EIM92397.1 - 0.0081 16.1 2.3 1.8 8.6 1.6 2.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 EIM92397.1 - 0.0098 15.2 0.1 5.8 6.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EIM92397.1 - 0.03 13.9 1.1 0.45 10.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair Y_phosphatase PF00102.22 EIM92398.1 - 4.6e-38 130.8 0.0 8e-37 126.8 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIM92398.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EIM92398.1 - 0.072 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain FhuF PF06276.7 EIM92398.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Pkinase PF00069.20 EIM92399.1 - 1.4e-39 135.8 0.0 1.7e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92399.1 - 1.3e-19 70.2 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92399.1 - 3.9e-05 22.7 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92399.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIM92399.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EIM92399.1 - 0.095 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HNH_2 PF13391.1 EIM92400.1 - 0.00028 20.5 0.0 0.0084 15.8 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease Pkinase PF00069.20 EIM92401.1 - 2.5e-40 138.2 0.0 3.2e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92401.1 - 1.4e-23 83.2 0.0 1.9e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92401.1 - 8.5e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92401.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CSTF2_hinge PF14327.1 EIM92403.1 - 2e-09 37.3 1.7 6.4e-09 35.7 1.2 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EIM92403.1 - 4.4e-09 35.4 3.3 1.3e-08 34.0 2.3 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF605 PF04652.11 EIM92403.1 - 0.75 9.1 10.6 0.76 9.1 7.3 1.1 1 0 0 1 1 1 0 Vta1 like Adaptin_N PF01602.15 EIM92404.1 - 1.8e-89 300.4 4.5 2.6e-89 299.9 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EIM92404.1 - 3.5e-65 217.6 0.3 1.3e-64 215.7 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EIM92404.1 - 2e-58 196.0 0.1 5.8e-58 194.5 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EIM92404.1 - 3.1e-14 53.0 0.3 0.00041 20.5 0.0 4.6 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 EIM92404.1 - 5.1e-07 29.2 0.0 0.02 14.9 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EIM92404.1 - 2.5e-05 24.1 3.7 0.087 12.6 0.9 3.6 2 2 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Gemini_V1 PF01524.12 EIM92404.1 - 0.0013 18.6 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Geminivirus V1 protein HEAT_EZ PF13513.1 EIM92404.1 - 0.0023 18.3 0.2 2.2 8.8 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 EIM92404.1 - 0.003 17.4 3.6 0.33 10.8 0.0 3.8 4 1 0 4 4 4 1 Protein of unknown function (DUF2435) ParcG PF10274.4 EIM92404.1 - 0.025 14.5 1.3 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 Parkin co-regulated protein ABC2_membrane PF01061.19 EIM92405.1 - 1.2e-74 250.0 45.4 2.9e-39 134.4 11.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIM92405.1 - 2.4e-33 115.3 0.0 5.8e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIM92405.1 - 3.3e-19 68.4 6.8 2.7e-16 59.1 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter cobW PF02492.14 EIM92405.1 - 9.3e-08 31.7 0.0 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 EIM92405.1 - 5e-06 26.5 0.2 1.4e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 EIM92405.1 - 5.6e-06 26.5 0.1 0.14 12.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIM92405.1 - 3.1e-05 23.8 0.0 0.082 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIM92405.1 - 4.5e-05 22.9 0.1 0.04 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 EIM92405.1 - 0.00015 20.9 37.3 0.0034 16.4 10.8 3.5 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 EIM92405.1 - 0.00029 21.6 0.0 0.31 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIM92405.1 - 0.00071 19.0 0.5 0.046 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EIM92405.1 - 0.0011 18.9 0.1 0.3 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIM92405.1 - 0.0069 15.5 0.0 0.04 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIM92405.1 - 0.008 15.6 0.1 4.1 6.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EIM92405.1 - 0.0085 16.3 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIM92405.1 - 0.0086 16.0 2.5 0.38 10.6 0.2 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EIM92405.1 - 0.014 14.8 0.1 0.27 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 EIM92405.1 - 0.041 13.1 0.0 0.55 9.4 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIM92405.1 - 0.091 12.7 0.0 20 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EIM92405.1 - 0.1 12.1 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIM92405.1 - 0.21 11.3 0.9 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 EIM92405.1 - 0.22 11.1 0.5 3 7.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Adaptin_N PF01602.15 EIM92407.1 - 4.1e-106 355.3 4.5 5.2e-106 355.0 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIM92407.1 - 2e-10 40.7 5.2 0.043 14.0 0.0 5.5 3 3 3 6 6 6 4 HEAT repeats Cnd1 PF12717.2 EIM92407.1 - 3.6e-08 33.4 2.4 0.00033 20.5 0.0 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EIM92407.1 - 2.7e-07 30.8 3.0 0.64 10.5 0.0 7.2 7 0 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 EIM92407.1 - 4.6e-06 26.2 2.9 30 5.0 0.0 6.4 6 0 0 6 6 6 0 HEAT repeat DUF2435 PF10363.4 EIM92407.1 - 0.0011 18.8 6.2 0.19 11.6 0.6 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) Arm PF00514.18 EIM92407.1 - 0.0069 16.1 1.3 0.88 9.4 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 EIM92407.1 - 0.29 11.0 12.2 8.7 6.3 0.0 5.4 6 1 1 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pkinase PF00069.20 EIM92408.1 - 3.8e-70 236.0 0.0 6.1e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92408.1 - 1.6e-51 174.8 0.0 2.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92408.1 - 8.2e-05 21.6 0.0 0.00067 18.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 EIM92408.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Involucrin_N PF10583.4 EIM92408.1 - 0.067 13.4 1.2 0.18 12.1 0.9 1.7 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus UQ_con PF00179.21 EIM92409.1 - 2.1e-22 79.0 0.0 4.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EIM92409.1 - 1.5e-05 24.6 0.1 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 UEV domain Cation_efflux PF01545.16 EIM92410.1 - 3.1e-31 108.5 3.9 3.7e-31 108.2 2.7 1.1 1 0 0 1 1 1 1 Cation efflux family ORC3_N PF07034.6 EIM92412.1 - 0.12 11.3 1.8 0.19 10.6 1.3 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus ABC_membrane PF00664.18 EIM92413.1 - 2e-69 234.0 27.0 1.5e-37 129.5 8.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM92413.1 - 1.1e-52 177.9 0.0 8.6e-30 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM92413.1 - 1.2e-07 31.9 0.4 0.013 15.4 0.1 4.5 4 1 0 4 4 3 1 AAA domain SMC_N PF02463.14 EIM92413.1 - 1.5e-06 27.6 5.1 0.0018 17.5 0.5 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EIM92413.1 - 2.2e-05 24.9 1.2 0.17 12.3 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIM92413.1 - 3.1e-05 23.9 1.4 0.042 13.8 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EIM92413.1 - 3.1e-05 24.7 0.3 0.1 13.4 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.1 EIM92413.1 - 7e-05 23.2 4.8 0.11 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EIM92413.1 - 0.00011 21.6 1.2 0.11 11.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EIM92413.1 - 0.00016 20.8 1.2 0.098 11.7 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 EIM92413.1 - 0.00054 19.4 4.1 0.085 12.4 0.2 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIM92413.1 - 0.0012 18.8 2.2 0.3 11.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain UPF0079 PF02367.12 EIM92413.1 - 0.0085 15.7 2.4 0.019 14.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EIM92413.1 - 0.009 14.6 2.9 0.51 8.9 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF258 PF03193.11 EIM92413.1 - 0.011 14.9 4.6 0.6 9.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIM92413.1 - 0.016 15.3 2.6 7 6.8 0.0 3.4 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EIM92413.1 - 0.033 13.6 1.9 0.15 11.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIM92413.1 - 0.036 13.9 1.2 9.8 6.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EIM92413.1 - 0.044 12.6 1.5 3.1 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 EIM92413.1 - 0.045 13.2 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EIM92413.1 - 0.062 13.1 4.0 0.98 9.2 0.2 2.6 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EIM92413.1 - 0.069 12.8 0.9 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIM92413.1 - 0.099 12.2 0.7 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 EIM92413.1 - 0.11 12.0 2.1 6.2 6.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 EIM92413.1 - 0.12 12.1 5.3 0.14 11.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EIM92413.1 - 0.14 11.1 0.2 22 3.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 EIM92413.1 - 0.19 12.0 2.9 11 6.3 0.2 3.4 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EIM92413.1 - 1.4 8.3 3.7 60 3.0 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Glutaredoxin PF00462.19 EIM92414.1 - 9.1e-18 64.0 0.0 1.2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EIM92414.1 - 2.3e-05 24.1 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EIM92414.1 - 0.00046 20.3 0.4 0.0014 18.8 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DUF3179 PF11376.3 EIM92414.1 - 0.0046 16.1 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3179) DUF836 PF05768.9 EIM92414.1 - 0.012 15.9 0.1 0.016 15.4 0.1 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 EIM92414.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.1 EIM92414.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 EIM92414.1 - 0.087 12.3 0.2 0.57 9.7 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Ub-RnfH PF03658.9 EIM92414.1 - 0.11 12.3 0.1 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 RnfH family Ubiquitin CBP PF12192.3 EIM92414.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Fungal calcium binding protein Complex1_49kDa PF00346.14 EIM92415.1 - 1.7e-127 424.1 0.0 2.1e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EIM92415.1 - 0.049 12.3 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase CIMR PF00878.13 EIM92416.1 - 2.9e-14 53.0 0.0 9.8e-06 25.3 0.0 2.5 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EIM92416.1 - 8.8e-05 21.8 0.2 0.00075 18.8 0.0 2.3 1 1 1 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EIM92416.1 - 0.00017 20.7 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor GPI-anchored PF10342.4 EIM92417.1 - 3.2e-10 40.3 0.5 3.2e-10 40.3 0.3 2.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2702 PF10863.3 EIM92417.1 - 0.04 13.6 0.5 0.089 12.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2702) PAP1 PF08601.5 EIM92417.1 - 2 8.0 12.2 2.3 7.8 8.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF566 PF04484.7 EIM92417.1 - 6.2 6.2 14.9 8.2 5.8 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Peptidase_M76 PF09768.4 EIM92418.1 - 4.2e-65 218.4 1.7 4.9e-65 218.2 1.2 1.0 1 0 0 1 1 1 1 Peptidase M76 family WLM PF08325.5 EIM92418.1 - 0.1 12.4 0.4 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 WLM domain ECH PF00378.15 EIM92419.1 - 3.3e-53 180.3 0.1 4.1e-53 180.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TPX2 PF06886.6 EIM92421.1 - 4.5e-06 26.6 20.1 4.5e-06 26.6 13.9 2.6 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) Fasciclin PF02469.17 EIM92422.1 - 8.1e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Aldo_ket_red PF00248.16 EIM92423.1 - 9.8e-63 211.6 0.0 1.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIM92424.1 - 9.3e-61 205.1 0.0 2.6e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family UDG PF03167.14 EIM92424.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.6 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily LEP503 PF15221.1 EIM92424.1 - 0.15 11.8 0.1 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Utp14 PF04615.8 EIM92426.1 - 1.8e-155 519.0 54.6 1.8e-155 519.0 37.9 2.7 1 1 1 2 2 2 1 Utp14 protein Oest_recep PF02159.10 EIM92426.1 - 0.03 14.4 2.1 0.079 13.0 1.5 1.7 1 0 0 1 1 1 0 Oestrogen receptor SNF2_N PF00176.18 EIM92427.1 - 6.9e-63 212.2 0.0 9.6e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIM92427.1 - 5.7e-13 48.5 0.0 1.5e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EIM92427.1 - 3.2e-12 46.2 0.0 4.3e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 HIRAN domain DEAD PF00270.24 EIM92427.1 - 2.4e-07 30.3 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIM92427.1 - 1e-06 28.7 0.0 3.3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EIM92427.1 - 5.4e-05 22.7 14.2 0.00011 21.7 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM92427.1 - 0.00022 21.1 14.6 0.0006 19.7 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIM92427.1 - 0.034 14.0 15.7 0.067 13.0 10.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIM92427.1 - 0.072 12.8 13.3 0.14 11.8 9.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 EIM92427.1 - 0.091 12.2 9.1 0.16 11.4 6.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Tim10_DDP PF02953.10 EIM92427.1 - 0.28 10.4 6.1 0.57 9.5 4.2 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Cpn60_TCP1 PF00118.19 EIM92428.1 - 2.2e-137 458.5 0.2 2.6e-137 458.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 EIM92429.1 - 8.7e-22 77.3 22.9 8.7e-22 77.3 15.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily BSP PF04450.7 EIM92430.1 - 3.5e-63 212.7 0.0 4e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EIM92430.1 - 2.9e-08 33.7 0.3 4.7e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EIM92430.1 - 0.018 14.7 0.3 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 SprT-like family Peptidase_M76 PF09768.4 EIM92430.1 - 0.1 12.0 0.2 0.25 10.7 0.1 1.7 2 0 0 2 2 2 0 Peptidase M76 family LSM PF01423.17 EIM92431.1 - 3.8e-17 61.5 0.2 4.9e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain zf-CpG_bind_C PF12269.3 EIM92432.1 - 0.0017 17.8 1.7 0.0037 16.7 1.2 1.5 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain HABP4_PAI-RBP1 PF04774.10 EIM92433.1 - 0.0048 17.3 12.4 0.0048 17.3 8.6 4.3 3 1 2 5 5 5 2 Hyaluronan / mRNA binding family DUF1180 PF06679.7 EIM92433.1 - 7.5 6.4 7.9 15 5.4 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Memo PF01875.12 EIM92434.1 - 1.6e-69 233.8 0.0 1.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PAP2 PF01569.16 EIM92435.1 - 9.4e-13 47.9 8.8 9.4e-13 47.9 6.1 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EIM92435.1 - 6.7e-05 22.6 1.7 0.0032 17.2 0.1 2.8 2 1 1 3 3 3 2 Divergent PAP2 family Rhabdo_matrix PF03397.9 EIM92435.1 - 0.13 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein Y_phosphatase PF00102.22 EIM92437.1 - 1.1e-50 172.1 0.0 1e-34 119.8 0.0 4.3 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIM92437.1 - 0.00032 21.0 0.0 0.00081 19.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EIM92437.1 - 0.088 13.0 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIM92437.1 - 0.27 11.2 1.4 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate NIF PF03031.13 EIM92439.1 - 1.5e-24 86.4 0.0 1.4e-21 76.8 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EIM92439.1 - 1.2e-10 41.0 0.4 2.1e-09 37.1 0.1 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EIM92439.1 - 3e-06 27.2 0.0 7.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SET PF00856.23 EIM92439.1 - 0.8 9.9 5.4 3.1 8.0 1.8 2.8 2 0 0 2 2 2 0 SET domain ETC_C1_NDUFA5 PF04716.9 EIM92440.1 - 2.6e-17 62.0 0.5 4.1e-17 61.4 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_L32p PF01783.18 EIM92441.1 - 3.2e-17 62.4 3.3 3.9e-17 62.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 EIM92441.1 - 0.0056 16.4 0.4 0.007 16.1 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.7 EIM92441.1 - 0.012 15.4 0.2 0.015 15.0 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EIM92441.1 - 0.016 15.1 1.6 0.13 12.2 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Stc1 PF12898.2 EIM92441.1 - 0.02 14.9 0.7 0.025 14.6 0.5 1.1 1 0 0 1 1 1 0 Stc1 domain GFA PF04828.9 EIM92441.1 - 0.031 14.2 0.8 0.69 9.8 0.5 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Prok-RING_1 PF14446.1 EIM92441.1 - 0.05 13.3 1.9 0.13 12.0 1.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-UBR PF02207.15 EIM92441.1 - 0.072 12.8 0.2 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Auto_anti-p27 PF06677.7 EIM92441.1 - 0.077 12.7 2.5 0.83 9.4 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1272 PF06906.6 EIM92441.1 - 0.1 12.4 1.5 0.17 11.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_Tnp_IS1595 PF12760.2 EIM92441.1 - 0.17 11.7 3.1 1.9 8.3 2.2 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF35_N PF12172.3 EIM92441.1 - 0.27 11.1 3.0 1.6 8.6 2.1 2.0 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.1 EIM92441.1 - 0.55 9.5 8.2 7.1 5.9 5.9 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DUF2752 PF10825.3 EIM92441.1 - 0.56 10.2 2.8 0.61 10.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2752) DNA_ligase_ZBD PF03119.11 EIM92441.1 - 1 9.1 5.2 1.1 9.0 0.9 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1936 PF09151.5 EIM92441.1 - 1.2 8.7 4.0 2.7 7.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zinc_ribbon_2 PF13240.1 EIM92441.1 - 1.3 8.5 4.2 6.3 6.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 EIM92441.1 - 1.5 9.0 6.8 2.1 8.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C4_Topoisom PF01396.14 EIM92441.1 - 1.6 8.3 4.5 2.6 7.6 0.2 2.2 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-LITAF-like PF10601.4 EIM92441.1 - 1.6 8.6 4.9 22 5.0 0.1 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain UPF0547 PF10571.4 EIM92441.1 - 2.9 7.6 5.4 19 5.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 EIM92441.1 - 7 6.7 6.0 18 5.4 0.2 2.2 1 1 1 2 2 2 0 zinc-finger Thiolase_N PF00108.18 EIM92442.1 - 5.2e-68 228.8 0.0 8.6e-68 228.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIM92442.1 - 7.4e-38 128.7 0.3 2.4e-37 127.0 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EIM92442.1 - 0.0021 17.6 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EIM92442.1 - 0.01 15.3 0.8 0.019 14.4 0.0 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Amidase PF01425.16 EIM92443.1 - 1e-101 341.0 0.0 1.2e-101 340.7 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF896 PF05979.7 EIM92443.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF3999 PF13163.1 EIM92444.1 - 0.057 12.3 0.2 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Ribosomal_S3_C PF00189.15 EIM92445.1 - 1.6e-16 60.2 0.0 3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EIM92445.1 - 2.4e-12 46.2 0.0 4.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIM92445.1 - 0.035 14.3 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Lyase_8 PF02278.13 EIM92446.1 - 1.3e-35 123.1 0.7 2e-35 122.4 0.5 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EIM92446.1 - 1.9e-23 82.8 0.1 3e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EIM92446.1 - 0.0028 17.6 0.1 0.0072 16.3 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain YqfD PF06898.6 EIM92446.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Claudin_2 PF13903.1 EIM92447.1 - 0.1 12.2 3.2 0.045 13.4 0.2 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CbtB PF09489.5 EIM92447.1 - 0.19 11.6 0.9 4.4 7.2 0.1 2.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Mpp10 PF04006.7 EIM92448.1 - 1.2e-98 331.0 76.7 9.9e-97 324.7 53.2 2.6 1 1 0 1 1 1 1 Mpp10 protein Daxx PF03344.10 EIM92448.1 - 0.0013 17.3 20.3 0.0013 17.3 14.0 3.5 3 1 0 4 4 4 1 Daxx Family SNARE PF05739.14 EIM92449.1 - 4.1e-06 26.3 2.3 4.1e-06 26.3 1.6 3.0 4 1 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 EIM92449.1 - 0.00047 20.1 4.6 0.25 11.4 0.1 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus PBP1_TM PF14812.1 EIM92449.1 - 3.7 7.9 11.5 0.65 10.3 1.5 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-F_leu_zip PF10473.4 EIM92450.1 - 0.0026 17.6 2.9 0.0047 16.7 2.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EIM92450.1 - 0.0038 16.9 3.8 0.0086 15.8 2.6 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EIM92450.1 - 0.0049 16.7 4.3 0.0074 16.1 3.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EIM92450.1 - 0.0061 16.1 1.6 0.0093 15.5 1.1 1.3 1 0 0 1 1 1 1 IncA protein MbeD_MobD PF04899.7 EIM92450.1 - 0.008 16.0 1.2 0.8 9.6 0.1 2.5 1 1 1 2 2 2 1 MbeD/MobD like MAD PF05557.8 EIM92450.1 - 0.011 13.9 2.0 0.015 13.4 1.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Tropomyosin_1 PF12718.2 EIM92450.1 - 0.013 15.3 6.5 0.021 14.6 4.5 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4047 PF13256.1 EIM92450.1 - 0.014 15.3 0.6 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) TMF_TATA_bd PF12325.3 EIM92450.1 - 0.051 13.3 1.4 0.088 12.5 0.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ebp2 PF05890.7 EIM92450.1 - 0.074 12.3 0.9 0.1 11.8 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 GAS PF13851.1 EIM92450.1 - 0.079 12.1 3.5 0.13 11.4 2.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 EIM92450.1 - 0.13 11.7 2.8 0.18 11.2 2.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 EIM92450.1 - 0.14 11.9 2.9 0.21 11.3 2.0 1.2 1 0 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.6 EIM92450.1 - 0.17 11.7 1.2 0.34 10.8 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SAD_SRA PF02182.12 EIM92451.1 - 5.8e-42 142.6 0.0 8.5e-42 142.0 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain DUF1180 PF06679.7 EIM92453.1 - 0.011 15.6 8.5 0.014 15.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF566 PF04484.7 EIM92453.1 - 1.3 8.4 9.0 1.6 8.2 6.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) CytochromB561_N PF09786.4 EIM92453.1 - 3.3 6.0 9.0 3.7 5.8 6.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Period_C PF12114.3 EIM92453.1 - 5.8 6.4 14.1 7.1 6.1 9.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pex14_N PF04695.8 EIM92453.1 - 7.7 6.5 10.7 8.7 6.3 7.4 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 EIM92453.1 - 9.1 4.0 16.7 11 3.6 11.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UPF0160 PF03690.8 EIM92455.1 - 3.4e-131 437.3 0.0 3.9e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Zn_clus PF00172.13 EIM92456.1 - 6.1e-07 29.2 7.7 8.6e-07 28.7 5.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.12 EIM92457.1 - 1.7e-42 144.9 0.0 2.2e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.16 EIM92458.1 - 1.1e-08 34.5 0.1 2.7e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L15e PF00827.12 EIM92459.1 - 1.5e-90 301.8 10.9 1.7e-90 301.6 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 RasGEF PF00617.14 EIM92460.1 - 9e-31 107.0 0.1 1.7e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIM92460.1 - 1.9e-10 40.7 0.1 6.5e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 EIM92460.1 - 6.6e-07 29.8 0.0 3.3e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIM92460.1 - 2.6e-06 26.8 0.0 5.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ras family MARVEL PF01284.18 EIM92461.1 - 0.00049 19.9 13.4 0.00064 19.5 9.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain CcmD PF04995.9 EIM92461.1 - 0.0072 16.0 0.4 0.0072 16.0 0.3 2.9 3 1 0 3 3 3 1 Heme exporter protein D (CcmD) DUF4418 PF14387.1 EIM92461.1 - 1.4 8.6 6.3 0.3 10.8 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Yip1 PF04893.12 EIM92461.1 - 2.4 7.6 15.7 22 4.5 11.1 2.0 1 1 0 1 1 1 0 Yip1 domain Methyltransf_23 PF13489.1 EIM92462.1 - 7.1e-09 35.5 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIM92462.1 - 0.0098 16.3 0.0 0.03 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIM92462.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIM92462.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIM92462.1 - 0.14 11.7 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Peroxidase_2 PF01328.12 EIM92463.1 - 2.5e-12 46.1 1.4 8.6e-12 44.3 0.9 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 Hexapep PF00132.19 EIM92464.1 - 7.2e-13 47.4 17.2 1e-07 31.1 1.4 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIM92464.1 - 7.5e-08 31.8 11.6 9e-07 28.3 1.6 3.8 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EIM92464.1 - 0.015 13.8 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase DEAD PF00270.24 EIM92465.1 - 4.7e-47 159.6 0.0 2.7e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM92465.1 - 9.1e-24 83.1 0.0 2.1e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM92465.1 - 0.0011 18.7 0.5 0.042 13.6 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIM92465.1 - 0.11 12.5 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Lipase_3 PF01764.20 EIM92466.1 - 1e-23 83.5 0.0 1.6e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIM92466.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIM92466.1 - 0.005 16.7 0.2 0.0096 15.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EIM92467.1 - 1.5e-24 86.4 36.2 5.7e-18 64.7 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_71 PF03659.9 EIM92468.1 - 4.4e-91 305.2 5.0 5.3e-91 304.9 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Apc4 PF12896.2 EIM92469.1 - 3.4e-37 127.7 0.0 6.8e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 bZIP_1 PF00170.16 EIM92470.1 - 0.00013 21.8 4.7 0.00013 21.8 3.3 2.2 2 1 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 EIM92470.1 - 0.2 11.9 0.5 0.36 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 EIM92470.1 - 0.55 9.7 2.1 0.82 9.2 1.5 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EIM92470.1 - 0.9 9.4 9.5 0.9 9.4 3.1 2.8 2 1 1 3 3 3 0 Basic region leucine zipper GPI2 PF06432.6 EIM92471.1 - 5.1e-86 288.5 14.3 5.7e-86 288.3 9.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Polysacc_synt_C PF14667.1 EIM92471.1 - 1.8 8.3 16.7 0.24 11.2 1.6 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Actin PF00022.14 EIM92474.1 - 1.2e-134 448.7 0.0 1.3e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_S24e PF01282.14 EIM92475.1 - 1.9e-33 114.1 0.0 2.8e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Tic20 PF09685.5 EIM92476.1 - 2.5e-06 27.4 1.8 3.6e-06 26.9 1.3 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF2207 PF09972.4 EIM92476.1 - 0.062 11.8 0.2 0.083 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) cEGF PF12662.2 EIM92477.1 - 0.0039 16.8 2.2 0.025 14.2 0.2 3.5 2 0 0 2 2 2 1 Complement Clr-like EGF-like HEAT PF02985.17 EIM92478.1 - 2.6e-48 157.7 18.4 0.0011 18.8 0.0 13.3 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 EIM92478.1 - 1.4e-38 131.0 8.0 9.8e-09 35.3 0.0 6.9 2 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EIM92478.1 - 4.6e-12 46.1 1.0 0.0085 16.4 0.0 6.8 3 1 5 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIM92478.1 - 3.7e-11 43.1 16.9 0.072 13.6 0.0 9.6 7 3 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EIM92478.1 - 3.8e-07 28.8 4.2 5.7e-05 21.6 0.4 3.7 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 EIM92478.1 - 1.2e-06 28.5 0.4 3.9e-05 23.5 0.0 3.6 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIM92478.1 - 7.2e-05 22.4 4.9 2.2 8.2 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EIM92478.1 - 0.021 13.1 3.4 0.56 8.4 0.1 3.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EIM92478.1 - 0.046 14.1 4.2 1.3 9.6 0.3 5.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Ecm29 PF13001.2 EIM92478.1 - 0.064 11.7 0.8 8.5 4.7 0.1 3.5 3 1 1 4 4 4 0 Proteasome stabiliser CIA30 PF08547.7 EIM92479.1 - 6.4e-36 123.5 0.0 8.3e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) HMG_box PF00505.14 EIM92480.1 - 8.7e-14 51.5 1.8 1.1e-13 51.1 0.4 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIM92480.1 - 0.00014 22.1 0.1 0.00033 20.9 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.15 EIM92481.1 - 4.4e-22 78.6 0.1 8.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain Abhydrolase_2 PF02230.11 EIM92482.1 - 6.1e-29 101.0 0.0 7.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIM92482.1 - 3.3e-05 23.6 0.0 5.8e-05 22.8 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIM92482.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIM92482.1 - 0.00076 19.4 1.0 0.0037 17.1 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIM92482.1 - 0.0034 16.6 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EIM92482.1 - 0.0058 16.2 0.0 0.0073 15.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EIM92482.1 - 0.071 12.5 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Arm PF00514.18 EIM92483.1 - 5.9e-67 219.4 30.4 3.6e-13 48.7 0.1 11.4 10 2 2 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIM92483.1 - 5.6e-25 87.4 9.1 1.1e-06 28.8 0.1 7.3 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 EIM92483.1 - 9e-19 65.8 16.7 0.013 15.4 0.0 10.3 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EIM92483.1 - 4.3e-17 62.0 9.4 0.011 16.1 0.2 8.4 5 2 4 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 EIM92483.1 - 2e-12 46.7 10.9 7.8e-08 31.7 2.0 3.3 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 EIM92483.1 - 9.9e-12 43.9 10.7 1.6e-09 36.6 0.4 3.0 2 1 0 3 3 3 2 Adaptin N terminal region KAP PF05804.7 EIM92483.1 - 3.9e-09 35.0 2.5 5.2e-09 34.5 1.7 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EIM92483.1 - 1.6e-06 27.5 9.9 0.0042 16.2 0.3 4.2 1 1 3 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.2 EIM92483.1 - 0.0017 18.2 3.6 1 9.1 0.1 4.4 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EIM92483.1 - 0.003 17.8 10.5 5.3 7.7 0.3 7.1 7 0 0 7 7 7 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIM92483.1 - 0.011 16.0 0.3 6.1 7.2 0.0 3.5 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EIM92483.1 - 0.04 13.8 4.5 9.7 6.1 0.0 4.5 2 1 3 5 5 5 0 V-ATPase subunit H DUF2454 PF10521.4 EIM92483.1 - 0.042 12.8 1.0 0.89 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Ribosomal_L33 PF00471.15 EIM92484.1 - 3.1e-09 36.9 0.0 4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 EIM92484.1 - 0.035 13.5 0.1 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Amidohydro_3 PF07969.6 EIM92485.1 - 9.3e-60 202.9 0.0 1.1e-59 202.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EIM92485.1 - 5.2e-10 39.5 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIM92485.1 - 3.4e-05 24.0 0.0 0.11 12.4 0.1 2.9 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EIM92485.1 - 0.00021 21.0 0.3 0.0007 19.3 0.2 2.0 1 0 0 1 1 1 1 Amidohydrolase GYF PF02213.11 EIM92486.1 - 3.7e-16 58.4 0.5 8.9e-16 57.2 0.3 1.7 1 0 0 1 1 1 1 GYF domain Acatn PF13000.2 EIM92487.1 - 6.8e-139 463.8 24.0 3.3e-64 217.3 9.3 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF1680 PF07944.7 EIM92488.1 - 9.1e-25 86.9 0.1 1.6e-23 82.7 0.0 2.0 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Pkinase PF00069.20 EIM92489.1 - 5.1e-31 107.7 0.0 6.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92489.1 - 9.2e-29 100.2 0.0 1.2e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIM92489.1 - 0.035 13.8 0.1 0.086 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIM92489.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EIM92489.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_72 PF03198.9 EIM92490.1 - 1.3e-92 310.1 0.4 1.8e-92 309.7 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EIM92490.1 - 2.2e-20 72.9 2.1 5.4e-20 71.6 1.4 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EIM92490.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 EIM92491.1 - 1e-14 53.9 0.1 1.4e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM92491.1 - 1.2e-10 41.1 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIM92491.1 - 2.1e-08 33.6 4.2 3.4e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.1 EIM92491.1 - 2.9e-08 33.4 0.1 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIM92491.1 - 0.00026 20.6 0.1 0.00047 19.8 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIM92491.1 - 0.0028 17.2 0.3 0.0046 16.5 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EIM92491.1 - 0.011 15.2 1.9 0.011 15.2 1.3 2.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger RRM_3 PF08777.6 EIM92491.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif RNA_bind PF08675.6 EIM92491.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain ABC_membrane PF00664.18 EIM92492.1 - 2.5e-43 148.5 31.0 1.2e-25 90.4 1.9 3.5 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIM92492.1 - 2.2e-41 141.3 0.1 7.1e-24 84.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIM92492.1 - 2.8e-09 37.3 5.4 0.021 14.8 0.0 4.3 2 2 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EIM92492.1 - 3.4e-08 33.1 0.0 0.0017 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIM92492.1 - 6.3e-07 28.8 2.1 0.15 11.2 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIM92492.1 - 3.6e-06 26.4 0.4 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIM92492.1 - 3.8e-06 27.3 0.1 0.00027 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIM92492.1 - 0.00012 21.1 0.0 0.029 13.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 EIM92492.1 - 0.00013 22.0 1.0 0.61 10.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EIM92492.1 - 0.00022 21.6 0.1 0.76 10.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EIM92492.1 - 0.00027 20.4 0.1 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EIM92492.1 - 0.00029 20.5 0.5 0.5 10.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIM92492.1 - 0.00032 21.4 0.0 2.5 8.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain Adeno_IVa2 PF02456.10 EIM92492.1 - 0.0019 16.9 0.1 0.0095 14.6 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 EIM92492.1 - 0.0024 17.8 0.4 1.5 8.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM92492.1 - 0.0026 16.9 0.1 0.71 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIM92492.1 - 0.0029 17.1 0.9 1.8 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 EIM92492.1 - 0.0067 16.2 3.7 0.11 12.2 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EIM92492.1 - 0.0091 15.8 1.4 0.79 9.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 EIM92492.1 - 0.01 15.9 0.2 1.2 9.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EIM92492.1 - 0.013 15.8 1.9 4.6 7.5 0.0 3.6 5 0 0 5 5 3 0 AAA domain AAA_5 PF07728.9 EIM92492.1 - 0.017 14.8 0.7 8.5 6.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 EIM92492.1 - 0.036 13.3 1.0 4.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein Arch_ATPase PF01637.13 EIM92492.1 - 0.037 13.7 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EIM92492.1 - 0.041 12.9 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EIM92492.1 - 0.049 13.0 0.0 4.7 6.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 EIM92492.1 - 0.13 12.0 0.0 6.1 6.6 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 EIM92492.1 - 0.21 11.0 0.9 4.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EIM92492.1 - 0.23 11.3 0.3 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIM92492.1 - 0.33 10.5 1.5 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EIM92492.1 - 1.9 7.9 3.8 2 7.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RhoGAP PF00620.22 EIM92493.1 - 2.1e-37 128.0 0.0 4.3e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIM92493.1 - 6.3e-08 32.6 1.6 5e-07 29.8 0.3 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4244 PF14029.1 EIM92494.1 - 0.029 13.4 0.6 0.067 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DNA_pol_A_exo1 PF01612.15 EIM92495.1 - 2.9e-12 46.3 0.0 3.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease SprB PF13573.1 EIM92496.1 - 0.022 14.3 0.1 0.022 14.3 0.1 3.4 4 0 0 4 4 4 0 SprB repeat DUF605 PF04652.11 EIM92496.1 - 0.19 11.0 4.8 0.23 10.8 3.3 1.2 1 0 0 1 1 1 0 Vta1 like Las1 PF04031.8 EIM92497.1 - 1e-42 145.3 0.0 1e-42 145.3 0.0 1.5 2 0 0 2 2 2 1 Las1-like DLH PF01738.13 EIM92498.1 - 7.1e-11 41.8 0.0 8.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIM92498.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FR47 PF08445.5 EIM92499.1 - 3.1e-05 23.6 0.0 0.00015 21.4 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 EIM92499.1 - 0.00046 20.1 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIM92499.1 - 0.0044 17.1 0.0 0.0091 16.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIM92499.1 - 0.0075 16.4 0.0 0.018 15.2 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Fe-S_biosyn PF01521.15 EIM92500.1 - 1.9e-20 72.8 0.0 2.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis F-box-like PF12937.2 EIM92501.1 - 4.2e-05 23.1 2.0 6.6e-05 22.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM92501.1 - 0.0012 18.3 0.0 0.0036 16.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Prenylcys_lyase PF07156.9 EIM92502.1 - 2.2e-41 141.9 0.0 3.1e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EIM92502.1 - 9.1e-11 41.6 0.0 2.5e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM92502.1 - 1.1e-08 34.3 0.0 0.0032 16.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIM92502.1 - 2.5e-07 30.1 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIM92502.1 - 4.2e-05 23.6 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIM92502.1 - 0.00024 20.8 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIM92502.1 - 0.0018 18.1 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIM92502.1 - 0.011 14.1 0.5 1.1 7.6 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EIM92502.1 - 0.065 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EIM92502.1 - 0.2 10.4 0.8 0.42 9.4 0.6 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Ammonium_transp PF00909.16 EIM92503.1 - 2e-113 378.8 22.1 2.5e-113 378.5 15.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family adh_short PF00106.20 EIM92504.1 - 5.7e-15 55.6 0.4 4.2e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM92504.1 - 4.2e-07 29.9 0.1 2.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM92504.1 - 0.00027 20.6 0.4 0.014 15.1 0.0 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EIM92504.1 - 0.0006 19.3 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIM92504.1 - 0.098 11.7 0.2 0.4 9.7 0.2 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) UMP1 PF05348.6 EIM92505.1 - 9.5e-22 77.3 0.6 1.1e-21 77.1 0.4 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.23 EIM92506.1 - 1.1e-20 73.9 0.3 1.6e-20 73.4 0.2 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EIM92506.1 - 1.2e-18 67.2 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIM92506.1 - 0.002 17.8 1.2 0.0031 17.2 0.1 1.9 2 0 0 2 2 2 1 LisH NAD_binding_6 PF08030.7 EIM92507.1 - 1.2e-23 83.7 0.0 2.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM92507.1 - 9e-22 76.9 0.0 2.2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIM92507.1 - 4.3e-15 55.9 11.7 4.3e-15 55.9 8.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIM92507.1 - 0.00021 21.3 0.0 0.00083 19.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIM92507.1 - 0.0028 18.1 0.0 0.14 12.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain HORMA PF02301.13 EIM92508.1 - 3.1e-35 121.5 0.0 3.6e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EIM92508.1 - 0.066 12.6 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 13 Ribonuclease_3 PF00636.21 EIM92509.1 - 2.9e-09 37.3 0.0 1.9e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIM92509.1 - 3.4e-07 30.2 0.0 3.9e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease-III-like IlvN PF07991.7 EIM92510.1 - 1.2e-48 164.6 0.1 1.8e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIM92510.1 - 5.5e-11 42.7 0.2 2.1e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIM92510.1 - 1.2e-06 28.5 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvC PF01450.14 EIM92510.1 - 6.2e-05 22.9 0.1 8.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EIM92510.1 - 9.9e-05 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIM92510.1 - 0.00011 21.9 0.2 0.001 18.8 0.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EIM92510.1 - 0.012 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIM92510.1 - 0.021 15.0 0.1 0.12 12.6 0.1 2.0 1 1 1 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EIM92510.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.20 EIM92511.1 - 9.2e-27 93.9 0.1 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM92511.1 - 4.2e-26 92.2 0.0 4.9e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIM92511.1 - 6.2e-14 52.0 0.0 8.9e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Dak1_2 PF13684.1 EIM92511.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Cupin_2 PF07883.6 EIM92512.1 - 6.4e-07 28.7 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EIM92512.1 - 0.099 12.2 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Auxin_BP PF02041.11 EIM92512.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Pex16 PF08610.5 EIM92513.1 - 1.8e-79 267.1 0.6 2.2e-79 266.9 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF904 PF06005.7 EIM92514.1 - 2.1 8.6 8.6 0.98 9.7 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) BTB PF00651.26 EIM92515.1 - 0.00012 22.0 0.2 0.0084 16.0 0.0 3.0 3 0 0 3 3 3 1 BTB/POZ domain FAD_binding_7 PF03441.9 EIM92518.1 - 1.3e-89 300.1 1.3 1.3e-89 300.1 0.9 1.9 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIM92518.1 - 3e-34 118.1 0.1 5.4e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EIM92518.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.8 1 1 0 1 1 1 0 Universal stress protein family CorA PF01544.13 EIM92519.1 - 4.1e-29 101.5 0.2 1.1e-13 50.8 0.0 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF947 PF06102.7 EIM92520.1 - 1.9e-37 128.6 16.9 3.4e-37 127.8 11.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF947) APG6 PF04111.7 EIM92520.1 - 1.2 8.1 8.5 2.6 7.0 5.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 TRP PF06011.7 EIM92521.1 - 1.8e-05 23.4 5.5 1.8e-05 23.4 3.8 2.3 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF4083 PF13314.1 EIM92521.1 - 8.9 6.2 9.0 20 5.0 0.9 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF2235 PF09994.4 EIM92522.1 - 1e-60 205.4 0.0 1.9e-60 204.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3850 PF12961.2 EIM92522.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3850) Abhydrolase_5 PF12695.2 EIM92522.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3923 PF13061.1 EIM92523.1 - 0.16 11.8 1.0 0.25 11.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) SNAP PF14938.1 EIM92524.1 - 1e-106 356.2 14.5 1.2e-106 356.0 10.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EIM92524.1 - 0.00033 20.2 7.6 0.25 11.2 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 EIM92524.1 - 0.0013 17.7 2.4 0.0068 15.3 1.6 1.9 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_6 PF13174.1 EIM92524.1 - 0.0049 17.2 3.9 2.7 8.6 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIM92524.1 - 0.005 16.7 10.5 0.02 14.7 3.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIM92524.1 - 0.57 10.0 4.1 24 4.9 0.0 4.0 5 1 0 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 EIM92524.1 - 1.4 9.7 9.4 7 7.7 0.0 5.7 5 1 1 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat PGM_PMM_I PF02878.11 EIM92525.1 - 2e-17 62.9 0.1 5.8e-08 32.3 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EIM92525.1 - 3.5e-11 42.9 0.2 1.4e-09 37.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EIM92525.1 - 1e-10 41.8 0.0 4.6e-10 39.7 0.0 2.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EIM92525.1 - 0.0033 17.4 0.3 0.016 15.2 0.2 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GATase_4 PF13230.1 EIM92528.1 - 3.5e-22 78.4 0.0 6.1e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIM92528.1 - 3.5e-10 39.9 0.0 7.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EIM92528.1 - 3e-08 32.7 0.0 1.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II ICE2 PF08426.5 EIM92529.1 - 2.8e-26 92.0 28.8 3.2e-15 55.6 10.5 3.1 1 1 1 2 2 2 2 ICE2 BRCT PF00533.21 EIM92530.1 - 7.2e-05 22.8 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain SDA1 PF05285.7 EIM92530.1 - 1.3 8.2 18.4 2.2 7.5 12.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIM92530.1 - 1.7 6.4 22.0 3.1 5.5 15.2 1.3 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EIM92530.1 - 8 5.3 11.4 16 4.3 7.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim17 PF02466.14 EIM92531.1 - 6.8e-13 48.7 11.6 9.7e-13 48.2 8.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family IstB_IS21_ATP PF08483.6 EIM92531.1 - 0.12 12.0 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal 5TM-5TMR_LYT PF07694.7 EIM92531.1 - 2.2 7.5 6.7 1.8 7.8 3.8 1.5 1 1 0 1 1 1 0 5TMR of 5TMR-LYT Nucleoporin_FG PF13634.1 EIM92532.1 - 0.00082 19.5 2.3 0.037 14.2 1.6 2.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region Cornifin PF02389.10 EIM92532.1 - 0.64 9.7 13.8 35 4.0 9.0 2.7 1 1 0 1 1 1 0 Cornifin (SPRR) family Fork_head_N PF08430.7 EIM92532.1 - 5.8 7.3 6.0 38 4.6 1.5 2.6 2 1 1 3 3 3 0 Forkhead N-terminal region NUC153 PF08159.7 EIM92533.1 - 8.7e-16 57.2 18.0 8.5e-14 50.8 0.8 3.8 3 0 0 3 3 3 3 NUC153 domain CS PF04969.11 EIM92534.1 - 9.1e-19 67.7 0.2 1.7e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 CS domain Ribosomal_L3 PF00297.17 EIM92534.1 - 0.063 12.6 0.2 0.08 12.3 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L3 PhosphMutase PF10143.4 EIM92534.1 - 0.1 12.2 0.1 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase PINIT PF14324.1 EIM92535.1 - 3.1e-40 137.5 2.0 5e-40 136.9 1.4 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EIM92535.1 - 2e-18 65.6 8.5 4.1e-18 64.6 5.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EIM92535.1 - 0.0022 17.4 1.8 0.0061 16.0 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EIM92535.1 - 0.0045 16.4 0.2 0.014 14.8 0.1 1.9 1 0 0 1 1 1 1 SAP domain LptE PF04390.7 EIM92535.1 - 0.16 11.6 0.7 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide-assembly Mito_carr PF00153.22 EIM92536.1 - 1.9e-65 216.6 6.1 1.4e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ResIII PF04851.10 EIM92537.1 - 6.4e-18 65.2 0.0 1.5e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIM92537.1 - 2.8e-15 56.1 0.0 8.5e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM92537.1 - 5.5e-14 51.7 0.0 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIM92537.1 - 7.2e-07 28.2 0.0 2e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EIM92537.1 - 0.0032 16.5 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.10 EIM92537.1 - 0.031 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Parvo_coat PF00740.13 EIM92537.1 - 0.22 10.4 0.3 0.36 9.7 0.2 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Indigoidine_A PF04227.7 EIM92538.1 - 2.8e-104 348.4 0.0 3.4e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein Asp23 PF03780.8 EIM92538.1 - 0.082 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Asp23 family MoaE PF02391.12 EIM92539.1 - 2.7e-30 104.5 0.0 3.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Baculo_E25 PF05274.6 EIM92539.1 - 0.063 12.8 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 Ribosomal_L4 PF00573.17 EIM92540.1 - 4.2e-63 212.2 0.2 4.7e-63 212.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 EIM92541.1 - 5.1e-38 130.0 1.0 5.8e-38 129.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.10 EIM92541.1 - 0.13 11.0 0.9 0.18 10.5 0.6 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Esterase PF00756.15 EIM92542.1 - 2e-36 125.7 0.0 5.1e-25 88.3 0.0 2.0 1 1 1 2 2 2 2 Putative esterase Abhydrolase_5 PF12695.2 EIM92542.1 - 5.4e-05 22.9 0.2 8.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIM92542.1 - 0.028 13.2 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 EIM92542.1 - 0.059 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Con-6 PF10346.4 EIM92543.1 - 3.3e-36 122.4 7.0 5.3e-18 64.1 1.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 EIM92543.1 - 0.059 13.2 0.3 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 52 YhzD PF14120.1 EIM92543.1 - 0.22 11.4 1.9 2.2 8.2 0.1 2.4 2 1 1 3 3 3 0 YhzD-like protein Serglycin PF04360.7 EIM92545.1 - 0.038 13.7 0.6 0.038 13.7 0.4 2.2 2 0 0 2 2 2 0 Serglycin Pkinase PF00069.20 EIM92546.1 - 0.098 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EIM92547.1 - 9.8e-42 142.8 0.0 1.5e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92547.1 - 4.4e-23 81.6 0.0 6.4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIM92547.1 - 0.005 16.9 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 FHA domain MMR_HSR1 PF01926.18 EIM92548.1 - 5.8e-16 58.4 0.0 4.7e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM92548.1 - 2.1e-05 23.8 0.1 0.00011 21.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIM92548.1 - 3.5e-05 23.0 0.0 7.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIM92548.1 - 0.00033 19.8 0.0 0.00065 18.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIM92548.1 - 0.027 14.9 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EIM92548.1 - 0.043 13.6 0.5 0.043 13.6 0.3 2.2 2 1 1 3 3 3 0 Dynamin family Alginate_lyase PF05426.7 EIM92549.1 - 5.2e-54 183.4 2.7 1.2e-51 175.6 0.2 2.2 2 0 0 2 2 2 2 Alginate lyase Arrestin_C PF02752.17 EIM92550.1 - 0.033 14.3 0.5 0.067 13.3 0.4 1.5 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain PdxJ PF03740.8 EIM92550.1 - 0.064 12.3 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ ARID PF01388.16 EIM92551.1 - 5.7e-09 35.7 0.0 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 EIM92551.1 - 0.014 14.2 0.3 0.12 11.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3518) TFIIA PF03153.8 EIM92551.1 - 3.4 7.4 10.8 6 6.6 7.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1764 PF08576.5 EIM92552.1 - 2.4e-08 34.6 6.8 7.7e-07 29.8 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ribosomal_60s PF00428.14 EIM92552.1 - 1.1 9.7 12.5 4.2 7.8 0.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD-oxidase_C PF02913.14 EIM92553.1 - 4.8e-55 186.5 0.0 6.1e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIM92553.1 - 4.1e-33 113.8 2.4 7.2e-33 112.9 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain Methyltransf_14 PF08484.6 EIM92553.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Myb_DNA-bind_2 PF08914.6 EIM92554.1 - 2.1e-09 37.0 1.3 5.5e-09 35.6 0.9 1.7 1 0 0 1 1 1 1 Rap1 Myb domain 2OG-FeII_Oxy_2 PF13532.1 EIM92554.1 - 0.16 11.7 1.3 0.42 10.3 0.9 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Rap1-DNA-bind PF09197.5 EIM92554.1 - 0.37 11.3 5.4 0.48 10.9 1.6 2.6 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.20 EIM92555.1 - 8.4e-69 231.5 0.0 1e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92555.1 - 4.9e-26 91.3 0.0 6.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92555.1 - 7.5e-06 25.1 0.0 0.00028 19.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIM92555.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.5 2 0 0 2 2 2 1 RIO1 family DUF2404 PF10296.4 EIM92556.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DDE_Tnp_4 PF13359.1 EIM92557.1 - 2.7e-17 62.8 0.0 4.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EIM92557.1 - 5.3e-06 25.9 0.1 0.00034 20.0 0.1 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EIM92557.1 - 0.00059 19.4 0.0 0.021 14.3 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain Trypsin_2 PF13365.1 EIM92559.1 - 0.00055 19.9 0.6 0.0081 16.1 0.4 2.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EIM92559.1 - 0.018 14.6 0.3 0.2 11.2 0.0 2.5 3 0 0 3 3 3 0 Trypsin Peptidase_S3 PF00944.14 EIM92559.1 - 0.027 13.9 0.1 0.088 12.2 0.0 1.9 2 0 0 2 2 2 0 Alphavirus core protein Peptidase_S32 PF05579.8 EIM92559.1 - 0.034 13.1 0.1 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EIM92559.1 - 0.095 11.1 3.4 0.81 8.0 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 EIM92559.1 - 0.099 12.0 1.9 0.17 11.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease L_biotic_typeA PF04604.8 EIM92560.1 - 0.039 13.5 0.1 0.59 9.8 0.0 2.5 2 0 0 2 2 2 0 Type-A lantibiotic RNA_pol_Rpb8 PF03870.10 EIM92561.1 - 6.2e-40 136.5 0.1 1.8e-39 135.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb8 Porin_OmpG PF09381.5 EIM92561.1 - 0.031 13.3 0.3 0.053 12.6 0.0 1.5 2 0 0 2 2 2 0 Outer membrane protein G (OmpG) Pkinase PF00069.20 EIM92562.1 - 3.7e-05 23.0 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92562.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIM92562.1 - 0.0038 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIM92562.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIM92562.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIM92562.1 - 0.28 10.0 0.0 0.44 9.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like GYF PF02213.11 EIM92564.1 - 1.9e-12 46.5 0.0 4.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain AMP-binding PF00501.23 EIM92565.1 - 5e-68 229.3 1.3 1.5e-67 227.8 0.9 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Cellulase PF00150.13 EIM92565.1 - 8.3e-50 169.5 0.0 1.7e-49 168.5 0.0 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AMP-binding_C PF13193.1 EIM92565.1 - 7.3e-20 71.7 0.1 2.4e-19 70.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBM_1 PF00734.13 EIM92565.1 - 6.6e-11 41.6 13.4 1.4e-10 40.6 9.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Complex1_LYR PF05347.10 EIM92566.1 - 0.00034 20.3 2.0 0.00089 19.0 1.4 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIM92566.1 - 0.019 15.1 1.9 0.019 15.1 1.3 1.7 2 0 0 2 2 2 0 Complex1_LYR-like Sec8_exocyst PF04048.9 EIM92567.1 - 3.6e-35 120.6 0.7 7.1e-35 119.7 0.5 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EIM92567.1 - 5.6e-09 35.3 0.3 1.1e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2305 PF10230.4 EIM92568.1 - 9.7e-49 166.1 0.0 1.2e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EIM92568.1 - 2.7e-10 40.5 0.9 2.7e-10 40.5 0.7 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM92568.1 - 0.00032 20.4 0.0 0.00084 19.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EIM92568.1 - 0.021 14.1 0.0 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_25 PF13649.1 EIM92569.1 - 1.3e-08 35.0 0.0 3.9e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIM92569.1 - 0.0051 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIM92569.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.18 EIM92570.1 - 9.3e-64 215.0 0.0 1.4e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EIM92570.1 - 4.3e-20 71.7 0.1 9.3e-20 70.6 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EIM92570.1 - 2.4e-14 52.9 0.0 5.7e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 EIM92570.1 - 1.4e-07 31.0 11.6 5.5e-07 29.0 0.3 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 EIM92570.1 - 1.1e-06 28.2 0.9 0.02 14.5 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Pox_F11 PF04943.7 EIM92570.1 - 0.45 9.3 0.4 2.3 6.9 0.2 2.0 1 1 1 2 2 2 0 Poxvirus F11 protein Ribonucleas_3_3 PF14622.1 EIM92571.1 - 2.2e-08 34.1 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIM92571.1 - 0.03 14.7 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain Glyco_hydro_20 PF00728.17 EIM92572.1 - 1.5e-38 132.8 1.1 8.1e-38 130.4 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EIM92572.1 - 8.7e-14 52.1 0.1 6.2e-13 49.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Laminin_G_3 PF13385.1 EIM92572.1 - 0.014 15.6 2.9 0.014 15.6 2.0 2.1 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Ima1_N PF09779.4 EIM92573.1 - 1.4e-25 90.2 3.7 2.1e-25 89.7 2.5 1.2 1 0 0 1 1 1 1 Ima1 N-terminal domain Hepar_II_III PF07940.8 EIM92575.1 - 1.5e-09 37.8 0.7 1.5e-09 37.8 0.5 1.9 2 0 0 2 2 2 1 Heparinase II/III-like protein Thiolase_N PF00108.18 EIM92576.1 - 6.9e-74 248.1 0.7 1.1e-73 247.4 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIM92576.1 - 1.4e-45 153.6 1.2 1.4e-45 153.6 0.8 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EIM92576.1 - 3.7e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EIM92576.1 - 3.9e-05 23.2 0.3 0.0058 16.2 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EIM92576.1 - 0.0019 17.7 1.0 0.0074 15.7 0.3 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Cpn60_TCP1 PF00118.19 EIM92577.1 - 2.6e-154 514.4 2.7 3e-154 514.2 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TatD_DNase PF01026.16 EIM92578.1 - 9e-49 165.9 0.0 1.1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase MR_MLE_C PF13378.1 EIM92578.1 - 0.026 14.5 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like Amidohydro_2 PF04909.9 EIM92578.1 - 0.035 13.6 0.0 0.33 10.4 0.0 2.4 3 0 0 3 3 3 0 Amidohydrolase Metallophos_2 PF12850.2 EIM92578.1 - 0.038 13.8 0.0 0.098 12.4 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_43 PF04616.9 EIM92579.1 - 1.2e-62 211.6 5.9 1.5e-62 211.2 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_transf_21 PF13506.1 EIM92580.1 - 1e-22 80.2 0.5 9.3e-19 67.3 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EIM92580.1 - 1.3e-17 64.4 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIM92580.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sec3_C PF09763.4 EIM92581.1 - 9.4e-168 559.5 5.8 1.3e-167 559.0 4.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EIM92581.1 - 1.1e-17 63.6 0.0 2.9e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EIM92581.1 - 4.7e-06 25.4 8.6 0.00061 18.4 1.5 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family DUF972 PF06156.8 EIM92581.1 - 7.7 6.9 7.9 5.4 7.4 2.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TB2_DP1_HVA22 PF03134.14 EIM92582.1 - 1.9e-25 88.4 10.4 2.6e-25 87.9 7.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 EIM92582.1 - 0.014 15.3 2.6 0.018 14.9 1.7 1.4 1 1 0 1 1 1 0 GtrA-like protein YwiC PF14256.1 EIM92582.1 - 0.089 12.8 5.5 0.14 12.2 3.8 1.3 1 0 0 1 1 1 0 YwiC-like protein Zn_clus PF00172.13 EIM92583.1 - 1.8e-07 30.9 10.6 3.2e-07 30.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIM92583.1 - 8.9e-06 24.7 0.0 2.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S16 PF00886.14 EIM92584.1 - 4.7e-14 51.8 0.1 6.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.14 EIM92585.1 - 1.2e-15 56.9 0.0 1.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.2 EIM92585.1 - 5.4e-12 45.8 0.2 8.7e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIM92585.1 - 2.2e-10 39.7 1.6 1.3e-09 37.3 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EIM92585.1 - 1.5e-09 38.1 0.2 3e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIM92585.1 - 1.7e-09 37.6 0.1 2.8e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM92585.1 - 3.8e-09 35.8 1.2 5.6e-07 29.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat CoA_binding PF02629.14 EIM92586.1 - 2.7e-29 101.5 1.8 5.4e-29 100.5 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EIM92586.1 - 1.9e-22 79.5 0.3 2.8e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EIM92586.1 - 4.7e-08 32.7 0.2 1.1e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EIM92586.1 - 4.3e-07 30.0 0.1 8.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EIM92586.1 - 0.0014 19.0 0.0 0.0042 17.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Xpo1 PF08389.7 EIM92587.1 - 3.7e-21 75.5 0.1 1.2e-19 70.6 0.0 3.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIM92587.1 - 5e-06 26.3 0.0 0.00019 21.2 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 EIM92587.1 - 0.01 16.3 0.3 12 6.5 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.17 EIM92587.1 - 0.057 13.5 0.1 14 6.0 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Septin PF00735.13 EIM92588.1 - 5.4e-122 406.2 0.0 5.4e-122 406.2 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIM92588.1 - 1.7e-06 27.9 0.0 4.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIM92588.1 - 3.5e-05 23.0 0.2 0.00036 19.7 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIM92588.1 - 0.00027 21.2 1.6 0.049 13.9 0.0 2.7 3 0 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 EIM92588.1 - 0.0013 18.1 2.0 0.051 12.9 0.0 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIM92588.1 - 0.0016 18.3 3.9 0.87 9.3 0.0 3.2 2 1 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 EIM92588.1 - 0.0037 17.3 0.0 0.054 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 EIM92588.1 - 0.0042 16.2 0.2 0.016 14.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EIM92588.1 - 0.0085 16.0 0.2 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 EIM92588.1 - 0.0092 15.3 0.0 0.055 12.8 0.0 2.3 2 1 0 2 2 2 1 Ras family AAA_10 PF12846.2 EIM92588.1 - 0.012 15.0 0.0 0.053 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EIM92588.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EIM92588.1 - 0.07 13.6 0.0 0.45 11.0 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EIM92588.1 - 0.098 12.1 0.2 9.9 5.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EIM92588.1 - 0.11 12.1 2.3 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 EIM92588.1 - 0.16 11.7 5.6 0.072 12.8 0.9 2.4 1 1 1 2 2 2 0 Streptococcal surface antigen repeat rRNA_processing PF08524.6 EIM92588.1 - 0.21 11.3 14.6 0.44 10.3 10.1 1.4 1 0 0 1 1 1 0 rRNA processing Phage_GPO PF05929.6 EIM92588.1 - 0.59 9.3 6.3 0.95 8.6 4.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 EIM92588.1 - 0.91 8.6 7.4 0.56 9.3 3.9 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit CN_hydrolase PF00795.17 EIM92590.1 - 1.2e-32 112.7 0.0 1.5e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.4 EIM92591.1 - 3.4e-33 114.4 0.0 4.8e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.8 EIM92592.1 - 4.7e-47 159.4 0.0 5.2e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_Tnp_IS1 PF03811.8 EIM92592.1 - 0.12 11.8 1.3 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 InsA N-terminal domain Terminase_GpA PF05876.7 EIM92592.1 - 0.17 10.2 1.0 0.73 8.1 0.7 2.0 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 EIM92592.1 - 2 8.2 5.0 20 5.0 2.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Pkinase PF00069.20 EIM92594.1 - 2.6e-69 233.2 0.0 5.2e-69 232.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92594.1 - 2.7e-45 154.4 0.0 4.2e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92594.1 - 1.5e-09 37.2 0.0 2.3e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EIM92594.1 - 8.2e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIM92594.1 - 0.00085 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EIM92594.1 - 0.021 14.5 0.0 0.13 11.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIM92594.1 - 0.15 11.4 0.0 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family CLTH PF10607.4 EIM92595.1 - 2.3e-36 124.6 0.4 2.6e-36 124.4 0.3 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIM92595.1 - 0.00015 21.3 0.1 0.00035 20.2 0.1 1.6 1 0 0 1 1 1 1 LisH Rrp15p PF07890.7 EIM92596.1 - 8.1e-22 77.6 8.4 8.1e-22 77.6 5.8 2.3 1 1 1 2 2 2 1 Rrp15p DIL PF01843.14 EIM92597.1 - 1.5e-22 79.4 1.8 2.8e-22 78.5 1.3 1.5 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.1 EIM92597.1 - 1.8e-08 34.6 0.1 5.2e-06 26.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIM92597.1 - 2.3e-08 33.4 1.7 0.0011 18.6 0.1 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.2 EIM92597.1 - 5.8e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIM92597.1 - 6.6e-06 26.2 0.1 8.9e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIM92597.1 - 1.2e-05 25.0 2.0 0.0013 18.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat FAST_1 PF06743.10 EIM92597.1 - 0.16 11.7 0.6 0.89 9.3 0.2 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF2451 PF10474.4 EIM92597.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) zf-RAG1 PF10426.4 EIM92598.1 - 0.069 13.1 0.2 0.23 11.4 0.1 1.9 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Rhomboid PF01694.17 EIM92599.1 - 2.5e-26 92.4 16.6 4.7e-26 91.5 11.5 1.4 1 0 0 1 1 1 1 Rhomboid family Epimerase PF01370.16 EIM92600.1 - 8.9e-09 35.1 0.2 4.1e-07 29.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIM92600.1 - 5.1e-08 31.9 0.1 1.5e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIM92600.1 - 4.1e-07 30.1 0.1 8.2e-07 29.1 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIM92600.1 - 7.9e-05 22.9 0.1 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EIM92600.1 - 8.4e-05 22.5 0.4 0.0003 20.7 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EIM92600.1 - 9.9e-05 21.4 0.1 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EIM92600.1 - 0.0001 22.0 0.1 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EIM92600.1 - 0.0043 16.3 1.1 0.0051 16.0 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EIM92600.1 - 0.016 14.1 0.3 0.034 13.0 0.1 1.7 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EIM92600.1 - 0.061 12.2 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIM92601.1 - 8.8e-10 37.7 0.0 2.2e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIM92601.1 - 3.2e-09 36.5 0.1 2.9e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIM92601.1 - 2.8e-07 30.7 0.1 5.2e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIM92601.1 - 5.4e-05 23.4 0.1 0.00016 21.9 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIM92601.1 - 8e-05 21.7 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EIM92601.1 - 0.0001 22.2 0.3 0.00045 20.1 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIM92601.1 - 0.00017 20.9 0.7 0.00026 20.3 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EIM92601.1 - 0.0005 19.7 0.1 0.0008 19.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EIM92601.1 - 0.01 14.7 0.1 0.038 12.9 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EIM92601.1 - 0.021 13.7 0.0 0.09 11.6 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cas1_AcylT PF07779.7 EIM92602.1 - 1.3e-157 525.1 28.7 1.5e-156 521.6 19.9 1.9 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EIM92602.1 - 7.4e-29 101.3 0.0 1.3e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cut8_C PF08559.5 EIM92603.1 - 0.14 11.9 0.3 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Cut8 six-helix bundle PPR_3 PF13812.1 EIM92604.1 - 0.0021 18.1 1.2 1.6 9.1 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain RNase_T PF00929.19 EIM92605.1 - 8.3e-08 32.6 0.0 4.7e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Mito_carr PF00153.22 EIM92606.1 - 4e-51 170.7 0.4 1.3e-16 60.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MHC2-interact PF09307.5 EIM92607.1 - 0.0092 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 CLIP, MHC2 interacting LSM PF01423.17 EIM92608.1 - 1.2e-19 69.5 0.1 1.4e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Arm PF00514.18 EIM92609.1 - 2.6e-89 290.3 12.2 2.5e-12 46.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIM92609.1 - 1.1e-24 86.5 0.4 8.9e-07 29.1 0.0 5.7 1 1 6 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 EIM92609.1 - 1.9e-23 82.2 1.9 7e-09 35.9 0.0 5.5 4 1 1 5 5 5 3 HEAT-like repeat IBB PF01749.15 EIM92609.1 - 7e-21 74.2 8.1 1.1e-20 73.5 5.6 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EIM92609.1 - 3.5e-15 54.6 2.3 9.3e-05 22.2 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 EIM92609.1 - 1.2e-06 27.8 0.1 0.03 13.4 0.0 4.1 2 1 1 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EIM92609.1 - 1.4e-06 26.9 0.0 0.00051 18.4 0.0 3.0 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 EIM92609.1 - 5.2e-06 26.3 1.6 0.032 14.1 0.0 4.4 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 EIM92609.1 - 0.00026 20.8 0.0 0.44 10.4 0.0 4.5 3 2 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 EIM92609.1 - 0.00093 19.4 0.5 0.59 10.7 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RNF111_N PF15303.1 EIM92609.1 - 0.022 14.2 1.6 0.031 13.8 1.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Glycos_trans_3N PF02885.12 EIM92609.1 - 0.03 13.9 0.0 4.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain V-ATPase_H_N PF03224.9 EIM92609.1 - 0.063 12.3 0.0 8.3 5.4 0.0 2.8 1 1 1 2 2 2 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 EIM92609.1 - 0.093 10.9 0.0 0.53 8.4 0.0 2.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit SURF6 PF04935.7 EIM92609.1 - 4.5 6.5 14.2 6.8 5.9 9.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 PC_rep PF01851.17 EIM92610.1 - 4.2e-32 108.5 22.2 1.1e-08 34.8 0.0 10.2 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIM92610.1 - 9.9e-24 83.4 0.2 4.2e-11 42.9 0.0 4.3 2 1 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EIM92610.1 - 1.8e-07 31.4 0.5 0.0066 16.9 0.0 4.4 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EIM92610.1 - 2.6e-07 30.1 0.2 1.6 8.9 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat Adaptin_N PF01602.15 EIM92610.1 - 0.17 10.1 0.1 0.78 7.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Med24_N PF11277.3 EIM92610.1 - 0.32 8.4 0.8 0.48 7.8 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal COX6A PF02046.10 EIM92611.1 - 3.3e-30 104.3 0.3 3.7e-30 104.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Helicase_C PF00271.26 EIM92613.1 - 5.9e-17 61.3 0.0 1.4e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIM92613.1 - 2.3e-16 59.7 0.0 4.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EIM92613.1 - 0.021 13.6 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EIM92613.1 - 0.062 13.1 0.0 0.23 11.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NADH_4Fe-4S PF10589.4 EIM92613.1 - 0.38 9.9 3.0 0.99 8.6 2.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region API5 PF05918.6 EIM92613.1 - 2.5 6.4 5.5 4 5.8 3.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Nucleoporin_C PF03177.9 EIM92614.1 - 7.4e-77 259.2 2.6 6.9e-43 147.0 1.2 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIM92614.1 - 3.4e-56 190.8 0.0 5.3e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DUF4598 PF15370.1 EIM92615.1 - 2.6e-15 56.6 0.3 4.1e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Helicase_Sgs1 PF11408.3 EIM92615.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Sgs1 RecQ helicase zf-CSL PF05207.8 EIM92616.1 - 8e-13 47.6 0.3 1.2e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EIM92616.1 - 1e-10 41.1 0.5 1.6e-10 40.5 0.1 1.5 2 0 0 2 2 2 1 DnaJ domain Exo5 PF09810.4 EIM92617.1 - 3.6e-63 213.7 0.0 2.7e-54 184.5 0.0 2.6 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease Ctr PF04145.10 EIM92618.1 - 1.5e-06 28.3 8.7 0.00038 20.5 3.0 2.4 1 1 1 2 2 2 2 Ctr copper transporter family MFS_1 PF07690.11 EIM92619.1 - 1.6e-12 46.7 51.8 2.8e-07 29.5 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily S1FA PF04689.8 EIM92619.1 - 0.33 10.8 1.6 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA Pkinase PF00069.20 EIM92620.1 - 2.4e-38 131.7 0.0 4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92620.1 - 2.2e-27 95.7 0.0 3.1e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92620.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIM92620.1 - 0.055 13.1 0.0 1.6 8.4 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family NAD_binding_2 PF03446.10 EIM92621.1 - 9.5e-23 80.8 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIM92621.1 - 5.6e-08 32.8 0.1 1.2e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EIM92621.1 - 2.6e-06 27.5 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EIM92621.1 - 2.9e-05 24.4 0.0 7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3343 PF11823.3 EIM92621.1 - 0.039 13.2 0.0 0.084 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Exo_endo_phos PF03372.18 EIM92622.1 - 2.7e-24 86.4 0.1 4.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.15 EIM92623.1 - 1.9e-110 369.6 0.0 2.9e-110 369.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIM92623.1 - 9.8e-59 197.5 0.5 1.9e-58 196.5 0.4 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIM92623.1 - 2.6e-13 50.0 2.7 0.00043 20.4 0.1 5.9 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.17 EIM92623.1 - 0.0016 18.3 7.8 5.6 7.3 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.11 EIM92623.1 - 0.064 13.7 2.2 8.9 7.1 0.1 4.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 EIM92623.1 - 0.074 12.8 3.3 0.61 9.9 0.0 3.4 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIM92623.1 - 0.14 12.0 0.6 40 4.2 0.1 4.2 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Fumble PF03630.9 EIM92624.1 - 4.7e-117 390.6 0.0 7.2e-90 301.2 0.0 2.8 2 1 0 2 2 2 2 Fumble Homeobox PF00046.24 EIM92625.1 - 5.9e-46 153.9 14.9 1.6e-16 59.6 0.3 3.5 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 EIM92625.1 - 6.3e-16 57.8 2.2 3.7e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 Homeobox KN domain HTH_3 PF01381.17 EIM92625.1 - 0.0022 17.7 0.5 1.3 8.8 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.3 EIM92625.1 - 0.038 13.0 0.8 11 5.1 0.0 3.1 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Aldo_ket_red PF00248.16 EIM92627.1 - 6.3e-47 159.7 0.0 7.2e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YCII PF03795.9 EIM92627.1 - 0.028 14.6 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 YCII-related domain Glyco_hydro_2 PF00703.16 EIM92628.1 - 1.1e-08 35.5 0.0 4.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EIM92628.1 - 0.00052 19.5 0.6 0.0015 18.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EIM92628.1 - 0.023 13.5 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3678 PF12435.3 EIM92629.1 - 0.0082 15.6 2.6 0.0082 15.6 1.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3678) DUF1858 PF08984.6 EIM92630.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) HA2 PF04408.18 EIM92632.1 - 5.5e-25 87.3 0.0 1.8e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM92632.1 - 1.4e-12 47.4 0.0 5.3e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EIM92632.1 - 2.8e-10 39.9 2.1 5.2e-10 39.0 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM92632.1 - 4.2e-09 36.1 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EIM92632.1 - 0.0011 17.9 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EIM92632.1 - 0.0029 17.7 0.1 0.0089 16.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIM92632.1 - 0.0052 16.5 0.1 0.02 14.6 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EIM92632.1 - 0.083 12.5 0.2 0.24 11.0 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EIM92632.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain HA2 PF04408.18 EIM92633.1 - 8.2e-30 102.8 0.1 2.5e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM92633.1 - 2.7e-29 101.3 0.0 5.5e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM92633.1 - 2.6e-12 46.4 0.0 6.9e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EIM92633.1 - 1.8e-07 31.1 0.1 4.1e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EIM92633.1 - 2.6e-06 27.0 0.0 4.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIM92633.1 - 9.9e-05 21.3 0.0 0.00023 20.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EIM92633.1 - 0.00036 20.6 0.1 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIM92633.1 - 0.00068 19.3 0.2 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIM92633.1 - 0.0016 18.0 0.0 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIM92633.1 - 0.042 14.1 0.4 2.8 8.2 0.1 3.0 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.10 EIM92633.1 - 0.048 13.4 0.1 4.3 7.1 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Syntaxin-6_N PF09177.6 EIM92634.1 - 0.03 14.7 5.8 0.24 11.8 0.0 3.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Sas10_Utp3 PF04000.10 EIM92634.1 - 0.04 14.1 0.8 0.04 14.1 0.6 3.7 2 2 1 3 3 3 0 Sas10/Utp3/C1D family Ipi1_N PF12333.3 EIM92634.1 - 0.1 12.5 1.0 0.39 10.7 0.7 2.0 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Sec1 PF00995.18 EIM92635.1 - 7.1e-144 480.5 0.0 8.2e-144 480.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Phage_Mu_Gam PF07352.7 EIM92635.1 - 0.008 15.7 0.1 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF2115 PF09888.4 EIM92635.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DnaJ PF00226.26 EIM92637.1 - 4.1e-20 71.2 4.1 7e-20 70.5 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 EIM92637.1 - 0.026 14.1 1.0 0.026 14.1 0.7 2.6 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain nlz1 PF12402.3 EIM92637.1 - 0.029 14.7 0.2 0.029 14.7 0.1 2.3 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 Gly-zipper_YMGG PF13441.1 EIM92637.1 - 0.22 11.0 15.8 0.19 11.2 4.8 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper DUF456 PF04306.8 EIM92637.1 - 0.25 11.3 3.9 0.19 11.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EIM92637.1 - 0.31 10.7 14.9 1.4 8.6 5.9 2.6 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.4 EIM92637.1 - 7.5 6.7 12.6 5.8 7.1 4.8 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide LIM PF00412.17 EIM92639.1 - 6.8e-15 54.8 21.6 5.5e-07 29.5 1.1 5.6 4 3 1 5 5 5 3 LIM domain DUF3268 PF11672.3 EIM92639.1 - 0.091 12.8 6.5 3 7.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3268) Dicty_REP PF05086.7 EIM92639.1 - 7.2 4.2 4.6 14 3.3 3.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HypA PF01155.14 EIM92639.1 - 8.3 6.1 9.3 4.5 7.0 0.0 3.6 4 0 0 4 4 4 0 Hydrogenase expression/synthesis hypA family FMN_dh PF01070.13 EIM92640.1 - 7.6e-112 373.6 0.0 1.1e-111 373.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIM92640.1 - 3.5e-20 71.5 0.0 6.5e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIM92640.1 - 0.00013 21.0 0.1 0.00035 19.6 0.0 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIM92640.1 - 0.00016 20.6 0.5 0.0027 16.6 0.1 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIM92640.1 - 0.0018 17.4 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Peptidase_M19 PF01244.16 EIM92640.1 - 0.049 12.5 0.0 0.12 11.2 0.0 1.8 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ThiG PF05690.9 EIM92640.1 - 0.073 12.1 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LNS2 PF08235.8 EIM92640.1 - 0.12 11.9 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SAP PF02037.22 EIM92641.1 - 0.015 14.7 1.0 0.03 13.8 0.7 1.5 1 0 0 1 1 1 0 SAP domain RmuC PF02646.11 EIM92641.1 - 0.2 10.4 1.6 0.31 9.8 1.1 1.2 1 0 0 1 1 1 0 RmuC family Pkinase PF00069.20 EIM92642.1 - 2e-63 213.9 0.0 2.4e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92642.1 - 1.4e-23 83.2 0.0 2.6e-23 82.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92642.1 - 0.0044 16.0 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92642.1 - 0.015 15.0 0.4 0.038 13.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIM92642.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ribosomal_L22e PF01776.12 EIM92643.1 - 5.9e-45 151.8 1.6 7.1e-45 151.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DKCLD PF08068.7 EIM92644.1 - 1.6e-29 101.6 0.1 6e-29 99.7 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EIM92644.1 - 1.2e-22 80.7 4.3 2.7e-20 73.0 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EIM92644.1 - 4.9e-21 74.2 1.7 9.9e-21 73.2 1.2 1.6 1 0 0 1 1 1 1 PUA domain Cyclin_N PF00134.18 EIM92646.1 - 5.7e-12 45.2 0.1 3.6e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIM92646.1 - 0.0018 18.0 0.0 0.006 16.3 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EIM92646.1 - 0.012 15.5 1.1 0.42 10.5 0.1 2.8 3 0 0 3 3 3 0 Cyclin, C-terminal domain Ribosomal_L13 PF00572.13 EIM92647.1 - 1.4e-26 93.0 0.0 2.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 PP-binding PF00550.20 EIM92648.1 - 2e-14 53.5 0.5 2.7e-14 53.1 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIM92648.1 - 1.4e-06 28.1 0.2 1.9e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier SGL PF08450.7 EIM92649.1 - 4.3e-64 216.2 0.0 6.1e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EIM92649.1 - 0.0043 16.9 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 Arylesterase PD40 PF07676.7 EIM92649.1 - 0.029 14.0 0.1 0.073 12.7 0.1 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Ribosomal_L17 PF01196.14 EIM92650.1 - 3.2e-35 120.5 0.1 4.4e-34 116.9 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L17 Sin_N PF04801.8 EIM92653.1 - 3.6e-23 82.1 0.0 5.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region HA2 PF04408.18 EIM92654.1 - 9.6e-19 67.2 0.0 2.6e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIM92654.1 - 4.1e-13 49.1 0.0 9.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIM92654.1 - 1.5e-12 47.1 0.1 3.7e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIM92654.1 - 2.8e-07 30.7 0.1 9.7e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EIM92654.1 - 1e-05 25.1 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIM92654.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 EIM92654.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EIM92654.1 - 0.056 13.7 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 EIM92654.1 - 0.092 11.8 0.5 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 KaiC SNF2_N PF00176.18 EIM92655.1 - 2.7e-71 239.8 5.6 4.8e-71 239.0 3.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EIM92655.1 - 7.3e-45 152.4 19.0 7.3e-45 152.4 13.2 2.6 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EIM92655.1 - 6.2e-13 48.4 0.0 1.6e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIM92655.1 - 4.3e-06 25.7 3.2 0.00015 20.6 0.0 2.6 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.15 EIM92656.1 - 4.9e-118 393.8 0.0 6.3e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EIM92656.1 - 1.1e-19 70.1 0.0 2.8e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EIM92656.1 - 0.031 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PEX11 PF05648.9 EIM92657.1 - 2.7e-49 167.4 1.3 3.1e-49 167.2 0.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Anth_synt_I_N PF04715.8 EIM92657.1 - 0.039 13.9 0.0 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Anthranilate synthase component I, N terminal region Cmc1 PF08583.5 EIM92658.1 - 9.6e-12 44.5 1.6 1.2e-11 44.1 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 EIM92658.1 - 0.13 12.3 0.4 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 EIM92658.1 - 1.2 9.1 4.0 11 6.0 2.7 2.1 1 1 1 2 2 2 0 CHCH domain Radical_SAM PF04055.16 EIM92659.1 - 6.7e-14 52.3 0.0 1.3e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily SET PF00856.23 EIM92660.1 - 3.3e-12 46.9 0.1 1.9e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 SET domain FliJ PF02050.11 EIM92660.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein CHAT PF12770.2 EIM92661.1 - 6.8e-30 104.1 0.0 9.8e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Trypsin_2 PF13365.1 EIM92663.1 - 6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Glucosamine_iso PF01182.15 EIM92665.1 - 1.4e-65 220.8 0.0 1.6e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GFO_IDH_MocA PF01408.17 EIM92666.1 - 1.4e-11 44.9 0.5 6.1e-11 42.8 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EIM92666.1 - 5.5e-05 22.3 0.0 8.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 EIM92666.1 - 0.0016 18.1 1.2 0.013 15.3 0.1 2.6 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.1 EIM92666.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Cyclin_N PF00134.18 EIM92668.1 - 1.2e-36 125.0 1.6 1.7e-36 124.6 0.3 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIM92668.1 - 8.8e-09 35.3 0.4 4.1e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF1602 PF07673.9 EIM92669.1 - 0.083 12.3 0.4 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) CLPTM1 PF05602.7 EIM92670.1 - 0.085 11.5 1.0 0.14 10.8 0.7 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF3533 PF12051.3 EIM92670.1 - 2 7.1 2.4 3.5 6.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Complex1_LYR PF05347.10 EIM92671.1 - 3.5e-13 49.1 1.0 4.7e-13 48.7 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIM92671.1 - 6.4e-10 39.1 0.9 7.6e-10 38.8 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Acyl-CoA_dh_1 PF00441.19 EIM92671.1 - 0.05 13.7 0.2 0.056 13.5 0.1 1.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RdRP PF05183.7 EIM92672.1 - 2.2e-144 482.3 0.0 2.8e-144 482.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sec7 PF01369.15 EIM92673.1 - 3.1e-37 128.1 0.0 5.1e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EIM92673.1 - 2.1e-11 44.0 0.0 4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIM92673.1 - 2e-08 34.3 0.1 4.2e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Hist_deacetyl PF00850.14 EIM92675.1 - 1.7e-82 277.2 0.0 2.5e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.5 EIM92675.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NIL domain 2OG-FeII_Oxy_3 PF13640.1 EIM92677.1 - 4.9e-11 43.0 0.3 8.8e-11 42.2 0.1 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIM92677.1 - 2.1e-05 24.0 0.2 4.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XPA_C PF05181.7 EIM92678.1 - 8e-27 92.5 0.8 1.5e-26 91.7 0.5 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EIM92678.1 - 0.00043 19.8 3.5 0.00043 19.8 2.4 2.5 3 0 0 3 3 3 1 XPA protein N-terminal PVL_ORF50 PF07768.6 EIM92678.1 - 2.5 8.1 13.6 0.44 10.5 1.6 3.3 4 0 0 4 4 4 0 PVL ORF-50-like family OrfB_Zn_ribbon PF07282.6 EIM92678.1 - 3.2 7.4 8.2 23 4.7 2.6 2.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain 4HBT_3 PF13622.1 EIM92679.1 - 3.5e-40 138.3 0.1 4.4e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EIM92679.1 - 1e-24 86.6 0.0 2e-20 72.7 0.0 3.1 2 2 1 3 3 3 2 Acyl-CoA thioesterase DUF1977 PF09320.6 EIM92679.1 - 0.059 13.6 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) DUF3964 PF13107.1 EIM92679.1 - 0.086 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Ribosomal_S27e PF01667.12 EIM92680.1 - 9.5e-29 98.7 1.5 1.2e-28 98.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EIM92680.1 - 0.0074 16.1 0.4 0.0097 15.7 0.3 1.1 1 0 0 1 1 1 1 IBR domain BTG PF07742.7 EIM92681.1 - 6.4e-11 41.8 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 BTG family Tmemb_cc2 PF10267.4 EIM92681.1 - 0.27 9.7 4.2 0.33 9.4 2.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RAP1 PF07218.6 EIM92681.1 - 0.34 8.9 5.6 0.42 8.6 3.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.6 EIM92681.1 - 1.4 6.6 11.7 1.9 6.2 8.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 EIM92681.1 - 3.6 5.7 9.1 5 5.2 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein CUT PF02376.10 EIM92683.1 - 0.14 11.9 0.4 0.32 10.8 0.3 1.7 1 1 0 1 1 1 0 CUT domain NicO PF03824.11 EIM92684.1 - 1.1e-62 211.9 18.0 1.1e-62 211.9 12.5 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EIM92684.1 - 0.17 10.6 8.8 0.03 13.1 3.2 1.9 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion BATS PF06968.8 EIM92685.1 - 3.4e-28 97.3 0.0 1.4e-27 95.3 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EIM92685.1 - 6.7e-16 58.9 0.0 1.2e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily RNase_T PF00929.19 EIM92686.1 - 5.8e-08 33.1 0.0 8.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease MinE PF03776.9 EIM92687.1 - 0.0085 15.5 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE BAF1_ABF1 PF04684.8 EIM92687.1 - 0.011 14.6 7.9 0.016 14.0 5.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3437 PF11919.3 EIM92688.1 - 1e-31 108.4 0.1 6.2e-31 105.9 0.1 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 EIM92688.1 - 5.9e-07 29.6 3.5 0.00034 20.8 0.1 6.0 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.17 EIM92688.1 - 1.6e-05 24.5 9.7 0.00074 19.3 0.0 6.4 8 0 0 8 8 8 1 HEAT repeat DUF1546 PF07571.8 EIM92688.1 - 0.00079 19.4 0.1 0.21 11.7 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EIM92688.1 - 0.0066 16.9 3.1 0.19 12.2 0.0 4.6 5 0 0 5 5 5 1 HEAT-like repeat Arm PF00514.18 EIM92688.1 - 0.014 15.2 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EIM92688.1 - 0.076 12.3 0.4 0.66 9.2 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal DcpS_C PF11969.3 EIM92689.1 - 4e-05 23.8 0.2 0.0001 22.4 0.1 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Translin PF01997.11 EIM92690.1 - 2.8e-29 102.1 0.0 3.5e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemopexin PF00045.14 EIM92690.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Hemopexin Pkinase PF00069.20 EIM92691.1 - 4.5e-64 216.1 0.0 7.3e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92691.1 - 8e-36 123.4 0.0 3.5e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM92691.1 - 5.1e-06 25.6 0.0 1.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92691.1 - 0.009 15.7 0.1 0.042 13.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIM92691.1 - 0.031 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TGS PF02824.16 EIM92692.1 - 4.7e-21 74.3 0.0 8.2e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIM92692.1 - 8.2e-18 64.4 0.1 1.6e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIM92692.1 - 1.4e-10 40.6 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIM92692.1 - 0.0011 18.8 0.2 0.069 12.9 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EIM92692.1 - 0.0029 18.0 0.0 0.0098 16.3 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein MCM PF00493.18 EIM92692.1 - 0.026 13.3 0.1 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family Chromo PF00385.19 EIM92693.1 - 0.00034 20.2 1.6 0.00079 19.0 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Med11 PF10280.4 EIM92694.1 - 1.2e-07 31.8 0.2 1.6e-07 31.3 0.2 1.5 1 1 0 1 1 1 1 Mediator complex protein TBCA PF02970.11 EIM92695.1 - 6e-20 71.1 5.4 7.3e-20 70.8 3.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A CRAL_TRIO_N PF03765.10 EIM92695.1 - 0.1 12.7 0.2 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain HLH PF00010.21 EIM92696.1 - 2.7e-08 33.3 8.2 2.7e-08 33.3 3.2 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Orbi_VP5 PF00901.12 EIM92696.1 - 0.097 10.8 4.2 0.13 10.4 2.9 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF3169 PF11368.3 EIM92697.1 - 0.67 9.1 4.1 0.092 11.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HLH PF00010.21 EIM92698.1 - 4.7e-11 42.1 1.3 2.7e-10 39.7 0.8 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FAD_binding_4 PF01565.18 EIM92699.1 - 2.7e-16 59.2 0.1 6.1e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIM92699.1 - 1.6e-06 27.8 0.5 4.2e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4231 PF14015.1 EIM92700.1 - 0.0058 16.6 1.7 0.0058 16.6 1.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4231) Het-C PF07217.6 EIM92702.1 - 4.2e-209 695.7 0.0 1.9e-207 690.2 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pox_A32 PF04665.7 EIM92703.1 - 0.025 13.9 0.1 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_19 PF13245.1 EIM92703.1 - 0.029 14.1 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EIM92703.1 - 0.034 14.3 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIM92703.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EIM92703.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EIM92703.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.4 EIM92703.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Bromodomain PF00439.20 EIM92704.1 - 7.1e-56 186.0 0.1 6.6e-18 64.4 0.0 3.8 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 EIM92704.1 - 1.4e-13 50.7 0.0 5.6e-07 28.9 0.0 3.2 2 1 1 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 EIM92704.1 - 0.0052 17.0 7.3 1.2 9.4 0.1 4.9 4 1 1 5 5 5 2 HEAT repeats Peptidase_MA_2 PF13485.1 EIM92704.1 - 0.0085 16.1 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 Peptidase MA superfamily LTV PF04180.9 EIM92705.1 - 1.9e-72 245.0 26.3 5.4e-70 237.0 10.5 2.4 2 0 0 2 2 2 2 Low temperature viability protein RabGGT_insert PF07711.6 EIM92705.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain PARP PF00644.15 EIM92706.1 - 4e-56 189.7 0.0 6.7e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EIM92706.1 - 9.6e-36 122.3 0.0 1.5e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EIM92706.1 - 1.2e-20 73.2 0.0 2.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 WGR domain DHO_dh PF01180.16 EIM92707.1 - 2.8e-18 65.9 0.0 3.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TRAPP PF04051.11 EIM92709.1 - 3.3e-39 133.8 0.0 4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cullin PF00888.17 EIM92710.1 - 5.7e-06 25.1 0.0 6.2e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family CDI PF02234.14 EIM92710.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor DNA_pol_B PF00136.16 EIM92712.1 - 2.5e-91 306.7 0.0 3.7e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIM92712.1 - 3.1e-19 69.0 0.0 8.6e-10 37.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIM92712.1 - 8.5e-14 51.3 4.9 1.5e-13 50.5 3.4 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EIM92712.1 - 0.35 9.4 0.1 0.57 8.7 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Aldose_epim PF01263.15 EIM92713.1 - 1e-33 116.7 0.0 1.1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pep3_Vps18 PF05131.9 EIM92714.1 - 2.1e-41 140.7 0.0 4.5e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EIM92714.1 - 3.8e-10 39.5 3.1 0.00044 19.8 0.3 3.1 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EIM92714.1 - 3.9e-05 23.3 4.1 7e-05 22.5 1.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIM92714.1 - 0.00011 21.8 2.9 0.00014 21.5 0.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.4 EIM92714.1 - 0.00029 20.9 0.0 0.00074 19.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.1 EIM92714.1 - 0.043 13.5 1.4 0.68 9.6 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM92714.1 - 0.12 12.1 1.2 0.77 9.5 0.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EIM92714.1 - 0.13 12.2 4.0 0.13 12.3 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIM92714.1 - 1.2 8.8 4.6 0.51 10.0 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cgr1 PF03879.9 EIM92715.1 - 3.4e-19 69.0 15.5 3.8e-19 68.8 10.8 1.0 1 0 0 1 1 1 1 Cgr1 family SPATIAL PF15256.1 EIM92715.1 - 0.076 13.0 4.5 0.078 13.0 3.1 1.1 1 0 0 1 1 1 0 SPATIAL GP41 PF00517.12 EIM92716.1 - 0.2 11.1 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Sec39 PF08314.6 EIM92717.1 - 5.3e-60 203.1 0.0 8.2e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 UPF0113 PF03657.8 EIM92718.1 - 3e-09 36.7 0.0 3.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) AMNp_N PF10423.4 EIM92718.1 - 0.14 11.7 0.0 1.3 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus p450 PF00067.17 EIM92719.1 - 7.9e-69 232.3 0.0 1.1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIM92720.1 - 3.8e-66 223.5 0.0 5.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NRDE-2 PF08424.5 EIM92721.1 - 1.9e-52 178.1 0.1 1e-51 175.7 0.3 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EIM92721.1 - 0.00018 21.8 16.2 0.1 13.2 0.1 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIM92721.1 - 0.00027 20.0 0.6 0.12 11.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIM92721.1 - 0.077 13.3 2.4 12 6.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIM92721.1 - 0.77 10.5 0.0 0.77 10.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UreD PF01774.12 EIM92723.1 - 5.2e-54 182.8 0.0 6.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Aldedh PF00171.17 EIM92724.1 - 4.3e-127 424.2 0.0 5.2e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIM92724.1 - 5.3e-08 31.9 0.0 8.1e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) CD4-extracel PF09191.5 EIM92724.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 CD4, extracellular MFS_1 PF07690.11 EIM92725.1 - 3.3e-25 88.5 35.7 2.4e-24 85.7 25.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M41 PF01434.13 EIM92726.1 - 2.3e-70 236.3 0.0 3.3e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIM92726.1 - 1.3e-42 145.1 0.0 2.4e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EIM92726.1 - 3.8e-13 49.5 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EIM92726.1 - 0.001 19.8 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIM92726.1 - 0.0019 18.3 0.1 0.059 13.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIM92726.1 - 0.0022 17.9 0.0 0.0095 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EIM92726.1 - 0.0028 16.4 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EIM92726.1 - 0.0029 17.3 0.0 0.0096 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIM92726.1 - 0.0044 16.7 0.7 0.014 15.0 0.5 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIM92726.1 - 0.0046 16.0 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIM92726.1 - 0.016 15.2 0.3 0.12 12.3 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EIM92726.1 - 0.021 13.9 0.0 0.046 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EIM92726.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EIM92726.1 - 0.063 12.6 1.1 0.24 10.7 0.4 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EIM92726.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EIM92727.1 - 1.4e-12 46.9 4.8 0.00016 21.4 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EIM92727.1 - 1.3e-05 25.0 0.0 0.42 10.2 0.1 4.7 6 1 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EIM92727.1 - 0.00015 19.7 0.0 0.0023 15.8 0.0 2.0 2 0 0 2 2 2 2 IKI3 family MFS_1 PF07690.11 EIM92728.1 - 9.2e-38 129.8 42.4 1.2e-37 129.4 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIM92728.1 - 1.6e-08 33.5 30.6 2e-07 29.9 21.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter G_glu_transpept PF01019.16 EIM92729.1 - 9.9e-147 489.4 0.0 1.1e-146 489.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Snf7 PF03357.16 EIM92730.1 - 3.8e-35 120.7 16.2 4.4e-35 120.5 11.2 1.0 1 0 0 1 1 1 1 Snf7 HAUS2 PF15003.1 EIM92730.1 - 0.012 14.6 5.3 0.015 14.3 3.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF458 PF04308.7 EIM92730.1 - 0.066 12.9 0.3 0.16 11.6 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF458) DUF2481 PF10654.4 EIM92730.1 - 0.42 10.3 7.0 0.27 10.9 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2481) Acyl-CoA_dh_C PF12806.2 EIM92730.1 - 0.68 9.7 7.0 2.9 7.7 0.5 2.4 1 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like RbsD_FucU PF05025.8 EIM92730.1 - 1.1 9.6 4.7 0.31 11.3 1.0 1.7 2 0 0 2 2 2 0 RbsD / FucU transport protein family NifW PF03206.9 EIM92730.1 - 2.8 8.0 6.0 2.3 8.3 0.1 2.8 1 1 2 3 3 3 0 Nitrogen fixation protein NifW DUF4559 PF15112.1 EIM92730.1 - 4.4 6.3 14.8 7.9 5.5 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Pro_isomerase PF00160.16 EIM92731.1 - 1.5e-42 145.4 0.0 2.6e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EIM92731.1 - 1.2e-05 24.7 0.1 7.3e-05 22.0 0.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EIM92731.1 - 0.019 14.8 0.1 0.053 13.4 0.0 1.7 1 1 0 1 1 1 0 U-box domain DUF4366 PF14283.1 EIM92731.1 - 0.055 12.8 0.6 0.081 12.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-Nse PF11789.3 EIM92731.1 - 0.11 12.0 0.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Toprim_3 PF13362.1 EIM92731.1 - 0.15 12.3 0.3 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Toprim domain PPR_2 PF13041.1 EIM92732.1 - 7.2e-39 131.5 0.1 1.6e-09 37.5 0.1 7.4 4 2 3 7 7 7 6 PPR repeat family PPR PF01535.15 EIM92732.1 - 3.6e-19 67.3 11.3 1e-05 25.1 0.0 10.0 9 2 0 9 9 9 4 PPR repeat PPR_3 PF13812.1 EIM92732.1 - 6.6e-18 63.4 9.9 0.028 14.6 0.0 9.6 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIM92732.1 - 2.2e-11 43.0 8.2 0.15 11.5 0.0 9.1 11 0 0 11 11 11 5 PPR repeat Sugar_tr PF00083.19 EIM92733.1 - 2.6e-102 342.7 13.7 3e-102 342.5 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM92733.1 - 6.1e-30 104.1 47.0 9.7e-25 87.0 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIM92733.1 - 1.1e-06 27.3 14.0 9.9e-05 20.9 3.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 EIM92733.1 - 0.091 12.7 0.4 0.091 12.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DEAD PF00270.24 EIM92734.1 - 5.5e-17 61.7 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM92734.1 - 7e-07 29.0 0.0 2.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIM92734.1 - 0.0061 16.4 0.1 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EIM92734.1 - 0.014 14.3 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4248 PF14053.1 EIM92734.1 - 0.048 13.2 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF4203 PF13886.1 EIM92735.1 - 2.1e-38 131.9 25.3 3.3e-38 131.2 17.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Prenyltransf PF01255.14 EIM92736.1 - 1.2e-78 263.2 0.0 1.5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ras PF00071.17 EIM92737.1 - 7.3e-29 100.2 0.0 8.6e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM92737.1 - 6.5e-11 42.7 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIM92737.1 - 1.4e-05 24.6 0.0 0.081 12.3 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EIM92737.1 - 0.019 13.6 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit FeoB_N PF02421.13 EIM92737.1 - 0.079 12.2 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-RING_2 PF13639.1 EIM92738.1 - 4.3e-06 26.4 5.8 1.1e-05 25.1 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.12 EIM92738.1 - 1.5e-05 24.3 0.3 2.8e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4_3 PF13920.1 EIM92738.1 - 0.00077 19.0 3.7 0.002 17.7 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 EIM92738.1 - 0.004 16.4 2.2 0.0069 15.6 1.5 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD PF00628.24 EIM92738.1 - 0.0059 16.2 6.9 0.011 15.3 4.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EIM92738.1 - 0.011 15.7 6.4 0.027 14.4 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIM92738.1 - 0.012 15.6 4.5 0.035 14.2 3.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger PHD_2 PF13831.1 EIM92738.1 - 0.055 12.7 1.1 0.11 11.8 0.8 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EIM92738.1 - 0.091 12.7 6.6 0.095 12.6 3.1 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.2 EIM92738.1 - 0.12 12.2 3.4 0.45 10.3 2.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon RINGv PF12906.2 EIM92738.1 - 0.13 12.3 7.3 0.26 11.3 5.1 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EIM92738.1 - 0.35 10.6 4.0 0.83 9.4 2.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EIM92738.1 - 0.56 9.8 5.4 1.2 8.7 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EIM92738.1 - 6.5 6.6 9.6 1.8 8.4 3.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger BTD PF09270.5 EIM92740.1 - 7.8e-27 93.9 0.0 2.3e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EIM92740.1 - 1.3e-26 93.7 0.1 5.9e-25 88.3 0.1 2.3 1 1 0 1 1 1 1 LAG1, DNA binding PK PF00224.16 EIM92741.1 - 6e-163 541.4 0.7 7.7e-163 541.0 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIM92741.1 - 1.2e-32 111.8 0.1 4.9e-32 109.9 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIM92741.1 - 0.0001 21.2 0.8 0.00032 19.6 0.3 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIM92741.1 - 0.0014 17.5 0.1 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 EIM92741.1 - 0.048 12.5 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 Gly_transf_sug PF04488.10 EIM92742.1 - 1.9e-05 25.0 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIM92742.1 - 0.035 13.2 0.2 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.14 EIM92743.1 - 3.8e-61 205.7 0.0 4.5e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 EIM92743.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain RINT1_TIP1 PF04437.8 EIM92745.1 - 1.5e-84 284.3 0.0 2.3e-84 283.7 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Prp19_bind PF06991.6 EIM92746.1 - 6.8e-65 219.0 21.8 1.4e-64 218.0 15.1 1.5 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain NAD_binding_8 PF13450.1 EIM92746.1 - 1.1e-12 47.8 0.0 3.8e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Strep_67kDa_ant PF06100.6 EIM92746.1 - 0.21 9.9 0.0 0.35 9.1 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family CHAT PF12770.2 EIM92747.1 - 0.00022 20.4 0.0 0.0005 19.2 0.0 1.6 1 1 0 1 1 1 1 CHAT domain CHAT PF12770.2 EIM92748.1 - 1.2e-15 57.4 0.0 2.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Rhodanese PF00581.15 EIM92749.1 - 1.4e-17 64.0 0.0 2.4e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Ctr PF04145.10 EIM92750.1 - 4.6e-24 85.1 0.0 5.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2107 PF09880.4 EIM92750.1 - 0.037 13.9 0.5 0.077 12.8 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) ATP_synt_I PF03899.10 EIM92750.1 - 1.6 8.9 8.5 4.9 7.3 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain Cohesin PF00963.13 EIM92751.1 - 0.02 14.7 4.8 0.079 12.8 0.3 2.7 2 1 0 2 2 2 0 Cohesin domain RAP1 PF07218.6 EIM92751.1 - 6.6 4.7 5.8 6.9 4.6 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UBACT PF02134.16 EIM92752.1 - 0.038 13.5 0.2 0.057 13.0 0.2 1.3 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein DUF782 PF05614.6 EIM92752.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) OrfB_Zn_ribbon PF07282.6 EIM92753.1 - 0.028 14.0 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rhodanese PF00581.15 EIM92754.1 - 6.5e-21 74.8 0.0 7.8e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.10 EIM92755.1 - 3.9e-119 397.8 2.3 4.3e-119 397.7 1.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Gti1_Pac2 PF09729.4 EIM92756.1 - 1.3e-38 132.5 0.1 5.4e-32 110.9 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family KH_1 PF00013.24 EIM92757.1 - 5.4e-32 109.2 0.7 5.3e-09 35.5 0.0 6.2 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 EIM92757.1 - 1.9e-20 72.0 4.6 7.2e-06 25.5 0.1 6.2 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 EIM92757.1 - 0.034 13.8 0.1 0.085 12.5 0.1 1.7 1 0 0 1 1 1 0 GHKL domain zf-RING_2 PF13639.1 EIM92758.1 - 5e-06 26.2 10.9 9.3e-06 25.3 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIM92758.1 - 0.00021 20.8 10.9 0.00041 19.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIM92758.1 - 0.00053 19.6 5.8 0.0011 18.6 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EIM92758.1 - 0.00071 19.5 12.0 0.0013 18.6 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM92758.1 - 0.0038 16.9 10.7 0.0084 15.8 7.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain RWD PF05773.17 EIM92758.1 - 0.023 14.5 0.4 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 RWD domain Baculo_IE-1 PF05290.6 EIM92758.1 - 0.055 13.1 2.4 0.092 12.4 1.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EIM92758.1 - 0.41 10.5 10.4 3.4 7.6 7.3 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EIM92758.1 - 4.8 7.0 9.0 94 2.9 5.7 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein RWD PF05773.17 EIM92759.1 - 1.7e-18 66.5 0.2 3.2e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EIM92759.1 - 7.5e-18 64.1 38.3 3.3e-10 39.6 2.4 4.3 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EIM92759.1 - 1.7e-06 27.7 9.8 1.7e-06 27.7 6.8 4.8 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 EIM92759.1 - 0.00027 20.5 5.4 0.00027 20.5 3.8 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM92759.1 - 0.0013 18.7 10.6 0.0013 18.7 7.4 5.3 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIM92759.1 - 0.0028 17.3 7.4 0.0028 17.3 5.1 4.5 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIM92759.1 - 0.003 17.3 5.5 0.003 17.3 3.8 5.1 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIM92759.1 - 0.0071 16.0 4.8 0.0071 16.0 3.3 3.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-piccolo PF05715.8 EIM92759.1 - 0.57 10.2 15.8 0.27 11.2 5.2 3.1 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE PF01363.16 EIM92759.1 - 8.3 6.3 32.1 0.41 10.5 0.7 3.7 3 1 0 3 3 3 0 FYVE zinc finger Urb2 PF10441.4 EIM92760.1 - 3.1e-32 111.9 0.0 3.1e-32 111.9 0.0 4.2 4 0 0 4 4 4 1 Urb2/Npa2 family DUF2766 PF10964.3 EIM92760.1 - 0.11 12.4 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) Beta_elim_lyase PF01212.16 EIM92761.1 - 5.1e-71 239.1 0.0 1.2e-70 238.0 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIM92761.1 - 0.0027 16.0 0.0 0.011 14.0 0.0 1.7 1 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme zf-met2 PF12907.2 EIM92762.1 - 5.8e-17 61.3 1.0 7.7e-17 60.9 0.7 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EIM92762.1 - 4.2e-06 27.3 14.1 4.2e-06 27.3 9.8 1.7 2 0 0 2 2 2 1 4F5 protein family zf-Tim10_DDP PF02953.10 EIM92763.1 - 1e-22 79.1 0.6 1.2e-22 78.9 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.27 EIM92764.1 - 2.3e-07 30.4 29.2 0.22 11.4 0.2 8.8 11 0 0 11 11 11 5 WD domain, G-beta repeat C2 PF00168.25 EIM92766.1 - 1.6e-69 229.7 11.3 1.2e-15 57.1 0.0 6.5 6 0 0 6 6 6 5 C2 domain NAD_binding_6 PF08030.7 EIM92768.1 - 7.7e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIM92768.1 - 3.9e-16 59.2 21.9 5.8e-16 58.7 8.4 2.7 2 1 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIM92768.1 - 5.5e-15 55.1 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 EIM92768.1 - 2 8.6 15.7 0.74 9.9 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) NAD_binding_6 PF08030.7 EIM92769.1 - 6.9e-18 65.0 0.0 1.6e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIM92769.1 - 1.7e-17 63.1 0.0 3.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIM92769.1 - 1.2e-16 60.8 11.3 1.2e-16 60.8 7.8 2.6 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIM92769.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain PTH2 PF01981.11 EIM92770.1 - 1.3e-36 124.7 0.1 1.5e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3377 PF11857.3 EIM92771.1 - 4.4 7.0 7.2 2.6 7.7 2.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) BNR PF02012.15 EIM92772.1 - 0.068 13.0 3.7 0.59 10.1 0.1 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat Peptidase_C48 PF02902.14 EIM92773.1 - 1.1e-38 133.0 1.6 3.7e-38 131.3 1.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arc_PepC PF06819.6 EIM92773.1 - 0.14 12.1 0.5 0.97 9.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain SNARE PF05739.14 EIM92774.1 - 1.7e-08 34.0 0.4 2.1e-08 33.7 0.3 1.1 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 EIM92774.1 - 0.014 15.0 1.4 0.021 14.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sec20 PF03908.8 EIM92774.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.5 1 1 0 2 2 2 0 Sec20 p450 PF00067.17 EIM92775.1 - 3e-51 174.3 0.0 3.5e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yippee-Mis18 PF03226.9 EIM92776.1 - 2.8e-24 84.9 0.5 3.1e-24 84.8 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EIM92776.1 - 0.0085 16.0 2.2 0.22 11.4 1.6 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Evr1_Alr PF04777.8 EIM92776.1 - 0.26 11.2 1.5 0.66 9.9 0.1 1.9 1 1 1 2 2 2 0 Erv1 / Alr family adh_short_C2 PF13561.1 EIM92778.1 - 9.2e-35 120.5 0.0 1e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM92778.1 - 1.5e-28 99.8 0.5 1.8e-28 99.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92778.1 - 7.4e-11 42.0 0.1 1e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIM92778.1 - 0.00017 20.8 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EIM92778.1 - 0.00026 20.5 0.1 0.0016 17.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIM92778.1 - 0.059 12.4 0.2 0.087 11.9 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EIM92778.1 - 0.12 12.1 0.6 0.3 10.9 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAN_4 PF14295.1 EIM92780.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 PAN domain Ras PF00071.17 EIM92782.1 - 1.7e-47 160.8 0.0 2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIM92782.1 - 2.4e-14 53.8 0.0 5.1e-14 52.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EIM92782.1 - 8.5e-05 22.0 0.0 0.00033 20.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EIM92782.1 - 0.00025 20.3 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EIM92782.1 - 0.015 14.6 0.2 0.6 9.3 0.0 2.9 1 1 2 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIM92782.1 - 0.045 13.7 0.0 0.086 12.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EIM92782.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Tim17 PF02466.14 EIM92783.1 - 8.5e-24 84.0 0.1 1.3e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Chromo PF00385.19 EIM92784.1 - 2.8e-13 49.2 0.5 5.8e-13 48.2 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 EIM92785.1 - 3.8e-56 188.9 0.0 6.8e-38 129.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIM92785.1 - 1.3e-10 41.4 0.1 0.0015 18.6 0.1 4.1 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EIM92785.1 - 1.8e-09 37.0 0.2 2.6e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.9 EIM92785.1 - 8.5e-09 35.2 0.0 0.002 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIM92785.1 - 9.4e-09 35.4 0.8 6.6e-05 22.8 0.2 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIM92785.1 - 1.9e-08 34.5 0.2 0.011 15.7 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 EIM92785.1 - 3.1e-08 32.9 0.1 0.0031 16.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIM92785.1 - 4e-08 32.8 2.8 0.0037 16.9 0.0 3.1 4 0 0 4 4 2 2 Part of AAA domain AAA_17 PF13207.1 EIM92785.1 - 6.8e-08 33.3 0.0 0.0048 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIM92785.1 - 1.1e-07 31.7 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EIM92785.1 - 2.7e-07 29.6 0.1 0.0058 15.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EIM92785.1 - 3.6e-07 30.5 0.0 0.013 15.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIM92785.1 - 5.2e-07 29.0 0.5 0.0096 15.1 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIM92785.1 - 5.2e-07 29.6 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EIM92785.1 - 8.8e-07 28.7 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.12 EIM92785.1 - 1.3e-06 27.9 0.1 0.064 12.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.6 EIM92785.1 - 3.3e-06 26.7 0.0 0.085 12.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIM92785.1 - 5e-06 25.7 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EIM92785.1 - 5.9e-06 26.4 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.21 EIM92785.1 - 7.3e-06 25.5 0.0 0.049 13.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 EIM92785.1 - 1.3e-05 24.9 0.0 0.069 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIM92785.1 - 1.5e-05 24.5 0.5 0.62 9.4 0.0 3.6 2 2 1 4 4 4 2 AAA domain AAA_30 PF13604.1 EIM92785.1 - 2.2e-05 24.1 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EIM92785.1 - 2.2e-05 23.6 0.5 0.012 14.7 0.1 2.6 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 EIM92785.1 - 0.00014 20.8 0.0 0.065 12.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 EIM92785.1 - 0.00016 21.4 0.9 0.43 10.2 0.0 3.0 4 0 0 4 4 2 2 NACHT domain AAA_24 PF13479.1 EIM92785.1 - 0.00024 20.7 1.3 0.31 10.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 EIM92785.1 - 0.00042 19.6 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 EIM92785.1 - 0.00073 19.4 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EIM92785.1 - 0.0012 18.8 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EIM92785.1 - 0.0017 18.6 0.1 0.34 11.2 0.1 2.5 2 0 0 2 2 2 1 ABC transporter Torsin PF06309.6 EIM92785.1 - 0.0025 17.6 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 Torsin DUF2075 PF09848.4 EIM92785.1 - 0.0026 16.7 0.8 0.8 8.6 0.0 2.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EIM92785.1 - 0.0034 16.9 0.1 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EIM92785.1 - 0.0046 15.8 0.2 1.8 7.3 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain KTI12 PF08433.5 EIM92785.1 - 0.0054 15.9 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.7 EIM92785.1 - 0.011 15.4 0.1 0.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EIM92785.1 - 0.012 14.4 0.3 1.6 7.5 0.0 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 EIM92785.1 - 0.02 13.5 0.1 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IPT PF01745.11 EIM92785.1 - 0.044 12.9 0.1 0.3 10.2 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.1 EIM92785.1 - 0.05 13.6 0.0 15 5.6 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain Zot PF05707.7 EIM92785.1 - 0.12 11.8 0.1 8.5 5.7 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.13 EIM92785.1 - 0.12 11.8 0.0 14 5.0 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EIM92785.1 - 0.13 12.0 0.6 21 4.7 0.0 3.0 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 EIM92785.1 - 0.17 10.8 0.1 20 4.0 0.0 2.9 2 1 0 3 3 3 0 KAP family P-loop domain DAP3 PF10236.4 EIM92785.1 - 0.23 10.3 0.0 16 4.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0121 PF03661.8 EIM92786.1 - 1.7e-20 73.3 0.1 2.1e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HAP PF03866.8 EIM92787.1 - 0.0058 16.4 4.5 0.0073 16.1 3.1 1.0 1 0 0 1 1 1 1 Hydrophobic abundant protein (HAP) DUF1700 PF08006.6 EIM92787.1 - 0.047 12.9 2.0 0.053 12.8 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CBS PF00571.23 EIM92788.1 - 3.1e-35 119.6 7.9 2.9e-09 36.5 0.1 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EIM92788.1 - 3.2e-05 23.5 0.0 9e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Frataxin_Cyay PF01491.11 EIM92790.1 - 7.6e-36 122.2 0.0 1.1e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain WD40 PF00400.27 EIM92792.1 - 4e-24 83.5 12.0 3.4e-07 29.8 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EIM92792.1 - 2.7e-05 23.9 0.0 0.14 11.8 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIM92792.1 - 0.11 10.7 0.0 0.3 9.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.3 EIM92792.1 - 0.14 10.2 0.0 0.36 8.8 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Bromodomain PF00439.20 EIM92793.1 - 2.5e-37 126.6 0.0 4.6e-20 71.3 0.0 2.7 2 1 0 2 2 2 2 Bromodomain Macoilin PF09726.4 EIM92793.1 - 2 6.5 7.6 3.2 5.9 5.3 1.4 1 0 0 1 1 1 0 Transmembrane protein Lin-8 PF03353.10 EIM92793.1 - 4 6.6 14.8 5.8 6.0 3.9 2.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist G-patch PF01585.18 EIM92794.1 - 7e-10 38.5 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 EIM92794.1 - 9e-06 25.6 5.2 1.5e-05 24.9 3.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM92794.1 - 3.7e-05 23.7 1.7 6.2e-05 23.0 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 EIM92794.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 EIM92794.1 - 0.0046 17.0 0.6 0.0076 16.3 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Thioredoxin_2 PF13098.1 EIM92794.1 - 0.58 10.3 2.9 1.3 9.2 2.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain RRM_6 PF14259.1 EIM92795.1 - 3.6e-10 39.6 0.0 8.1e-08 32.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIM92795.1 - 1.3e-07 31.5 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EIM92795.1 - 3.6e-06 26.5 4.9 6.7e-06 25.6 3.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIM92795.1 - 1.5e-05 24.7 0.0 3.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIM92795.1 - 0.002 17.7 0.1 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIM92795.1 - 0.0082 15.9 0.1 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif Abhydrolase_4 PF08386.5 EIM92796.1 - 3.8e-19 68.4 0.0 6.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EIM92796.1 - 3.1e-14 53.0 0.0 3e-13 49.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM92796.1 - 6.6e-10 39.2 0.0 4.5e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM92796.1 - 0.00055 19.6 0.0 0.029 14.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EIM92796.1 - 0.21 10.7 0.5 0.43 9.7 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Laminin_I PF06008.9 EIM92797.1 - 0.0063 15.8 4.0 0.0076 15.5 2.7 1.1 1 0 0 1 1 1 1 Laminin Domain I Phage_GPO PF05929.6 EIM92797.1 - 0.043 13.0 0.3 0.05 12.8 0.2 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_DNA_bd PF12329.3 EIM92797.1 - 0.26 11.1 2.5 5.1 6.9 2.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SEEK1 PF15357.1 EIM92797.1 - 0.57 10.0 5.9 0.82 9.5 4.1 1.2 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 DUF2762 PF10960.3 EIM92797.1 - 1.9 8.2 4.7 9.4 6.0 3.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) Abhydrolase_1 PF00561.15 EIM92798.1 - 5.7e-12 45.6 0.1 9.1e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EIM92798.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EIM92798.1 - 4.6e-06 26.6 0.3 1.8e-05 24.7 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 EIM92799.1 - 1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF897 PF05982.7 EIM92800.1 - 0.017 13.9 0.1 0.035 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF897) DUF1705 PF08019.7 EIM92800.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1705) UPF0233 PF06781.7 EIM92800.1 - 1.9 8.1 0.0 1.9 8.1 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) NPL4 PF05021.10 EIM92801.1 - 1.6e-94 316.4 0.0 2.1e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EIM92801.1 - 5.2e-61 204.6 0.0 8e-61 204.0 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EIM92801.1 - 3.5e-05 23.9 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.10 EIM92802.1 - 2.3e-11 43.3 9.5 4.2e-11 42.4 6.5 1.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIM92802.1 - 3.3e-08 33.3 8.9 1.7e-07 31.0 6.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EIM92802.1 - 5.9e-05 23.2 3.5 6.1e-05 23.2 2.4 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2205 PF10224.4 EIM92802.1 - 0.0023 17.4 0.9 0.0024 17.4 0.6 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 EIM92802.1 - 0.0051 16.7 0.2 0.0068 16.3 0.1 1.3 1 1 0 1 1 1 1 TSC-22/dip/bun family DivIC PF04977.10 EIM92802.1 - 0.02 14.3 0.8 0.02 14.3 0.5 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 EIM92802.1 - 0.032 14.0 1.6 0.037 13.8 1.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3734 PF12536.3 EIM92802.1 - 0.041 14.0 0.2 0.05 13.7 0.2 1.1 1 0 0 1 1 1 0 Patatin phospholipase Shugoshin_N PF07558.6 EIM92802.1 - 0.05 13.3 0.3 0.085 12.5 0.2 1.6 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HSBP1 PF06825.7 EIM92802.1 - 0.065 12.8 0.3 0.38 10.3 0.1 1.9 1 1 1 2 2 2 0 Heat shock factor binding protein 1 OmpH PF03938.9 EIM92802.1 - 0.093 12.6 0.3 0.1 12.5 0.2 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EIM92802.1 - 0.093 12.3 0.7 0.087 12.4 0.5 1.1 1 0 0 1 1 1 0 IncA protein ApoLp-III PF07464.6 EIM92802.1 - 0.11 12.4 0.5 0.13 12.2 0.4 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1151 PF06625.6 EIM92802.1 - 0.12 12.1 2.6 0.12 12.1 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF972 PF06156.8 EIM92802.1 - 0.13 12.5 0.2 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CASP_C PF08172.7 EIM92802.1 - 0.14 11.1 1.1 0.16 11.0 0.7 1.1 1 0 0 1 1 1 0 CASP C terminal DUF2216 PF10226.4 EIM92802.1 - 0.16 11.4 1.6 0.16 11.4 1.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Seryl_tRNA_N PF02403.17 EIM92802.1 - 0.17 11.9 1.3 0.18 11.8 0.9 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phlebovirus_NSM PF07246.6 EIM92802.1 - 0.24 10.5 1.5 0.24 10.5 1.1 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CHCH PF06747.8 EIM92803.1 - 1.5e-07 31.0 11.3 4.9e-05 23.1 2.5 2.2 1 1 1 2 2 2 2 CHCH domain Pet191_N PF10203.4 EIM92803.1 - 0.0029 17.6 3.1 0.008 16.2 2.3 1.6 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 EIM92803.1 - 0.049 13.0 0.9 0.064 12.6 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DinB_2 PF12867.2 EIM92808.1 - 1.9e-09 37.9 0.1 2.4e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.7 EIM92808.1 - 0.00047 19.9 0.1 0.00059 19.5 0.1 1.1 1 0 0 1 1 1 1 DinB family ATP-grasp_2 PF08442.5 EIM92809.1 - 1.7e-68 229.9 0.8 2.8e-68 229.2 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EIM92809.1 - 1.6e-26 92.7 0.1 3.2e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EIM92809.1 - 4e-09 36.0 1.3 8.5e-08 31.6 0.3 2.6 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EIM92809.1 - 0.00069 19.2 0.4 0.0021 17.6 0.3 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EIM92809.1 - 0.0089 15.7 0.1 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Spt20 PF12090.3 EIM92810.1 - 0.42 9.9 8.9 1 8.6 2.4 2.2 2 0 0 2 2 2 0 Spt20 family BCAS2 PF05700.6 EIM92812.1 - 4.4e-50 170.2 5.7 5.1e-50 169.9 3.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.4 EIM92812.1 - 0.00031 20.4 0.3 0.00054 19.6 0.2 1.5 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Baculo_PEP_C PF04513.7 EIM92812.1 - 0.014 15.2 0.8 0.023 14.5 0.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Complex1_30kDa PF00329.14 EIM92813.1 - 1.3e-34 118.4 0.0 2.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2413 PF10310.4 EIM92814.1 - 4.6e-74 249.8 2.5 4.1e-73 246.7 1.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) DUF1726 PF08351.6 EIM92814.1 - 0.0091 15.6 0.0 0.031 13.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Carbpep_Y_N PF05388.6 EIM92814.1 - 0.08 13.1 0.3 0.37 10.9 0.1 2.0 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Abhydrolase_1 PF00561.15 EIM92815.1 - 3.5e-09 36.5 0.6 5.8e-09 35.8 0.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EIM92815.1 - 2.6e-06 27.2 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EIM92815.1 - 7.6e-05 22.6 0.0 0.00026 20.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family MR_MLE_C PF13378.1 EIM92815.1 - 0.035 14.0 0.0 0.42 10.5 0.0 2.7 2 1 0 2 2 2 0 Enolase C-terminal domain-like Mito_carr PF00153.22 EIM92816.1 - 9.6e-23 79.7 0.0 1.2e-08 34.5 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein Aminotran_1_2 PF00155.16 EIM92817.1 - 3.4e-14 52.5 0.0 7e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Endotoxin_M PF00555.14 EIM92817.1 - 0.039 13.7 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 delta endotoxin Metallophos PF00149.23 EIM92818.1 - 1.6e-06 27.6 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIM92818.1 - 0.00049 19.9 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.2 EIM92819.1 - 2.3e-07 30.4 0.0 9.1e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIM92819.1 - 0.0069 16.0 3.3 1.1 9.0 0.0 3.1 3 0 0 3 3 3 2 F-box domain His_Phos_1 PF00300.17 EIM92820.1 - 1.1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.7 EIM92821.1 - 3.1e-31 107.3 3.5 3.5e-31 107.1 1.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIM92821.1 - 5.1e-17 61.6 0.2 1.3e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIM92821.1 - 1.3e-05 26.1 0.0 2.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIM92821.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PIN PF01850.16 EIM92821.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 PIN domain RNase_T PF00929.19 EIM92822.1 - 3.8e-12 46.7 0.0 1.2e-11 45.1 0.0 1.8 1 1 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.1 EIM92822.1 - 0.046 13.5 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily MFS_1 PF07690.11 EIM92823.1 - 8.9e-23 80.5 72.5 5.7e-22 77.8 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIM92823.1 - 5.6e-05 22.8 1.5 0.00024 20.8 1.0 2.1 1 0 0 1 1 1 1 MFS_1 like family PTH2 PF01981.11 EIM92824.1 - 1.5e-33 114.8 0.0 1.7e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RNase_T PF00929.19 EIM92825.1 - 3.7e-11 43.5 0.0 9.9e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 Exonuclease RNase_T PF00929.19 EIM92826.1 - 0.00011 22.4 0.0 0.00084 19.6 0.0 1.9 2 0 0 2 2 2 1 Exonuclease GMC_oxred_C PF05199.8 EIM92826.1 - 0.11 12.7 0.1 1 9.6 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase RNase_H_2 PF13482.1 EIM92826.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily Pkinase PF00069.20 EIM92827.1 - 4.4e-50 170.2 0.0 2.9e-49 167.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92827.1 - 3e-33 114.9 0.0 7.1e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIM92827.1 - 0.012 14.5 0.0 0.075 11.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Nop14 PF04147.7 EIM92827.1 - 0.048 11.5 0.5 0.067 11.1 0.4 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.4 EIM92827.1 - 1.6 7.4 4.3 2.5 6.8 3.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.20 EIM92828.1 - 3.2e-45 154.3 0.0 4.1e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92828.1 - 1.5e-11 43.8 0.0 1.6e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sgf11 PF08209.6 EIM92829.1 - 3.8e-11 42.0 0.7 7.5e-11 41.1 0.5 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Prok-RING_2 PF14445.1 EIM92829.1 - 0.22 11.4 1.5 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 EF-hand_1 PF00036.27 EIM92830.1 - 1.2e-37 124.2 5.5 3.1e-09 35.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIM92830.1 - 1.2e-32 111.8 2.0 2.3e-15 56.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIM92830.1 - 1.5e-28 98.1 8.2 4.2e-11 42.2 0.2 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIM92830.1 - 2.8e-28 95.2 2.5 6.4e-09 34.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIM92830.1 - 1.5e-27 93.6 4.4 5.7e-08 31.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIM92830.1 - 2.4e-13 49.7 0.1 2.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EIM92830.1 - 2.3e-05 24.4 0.0 0.15 12.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EIM92830.1 - 3.8e-05 23.2 0.0 0.19 11.3 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EIM92830.1 - 0.00019 21.0 0.8 0.55 9.9 0.0 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 EIM92830.1 - 0.00033 20.4 0.1 0.53 10.0 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EIM92830.1 - 0.00059 19.4 0.0 0.41 10.1 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein LNS2 PF08235.8 EIM92830.1 - 0.033 13.7 0.0 5.1 6.6 0.0 2.1 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1103 PF06513.6 EIM92830.1 - 0.053 12.9 0.6 0.067 12.5 0.4 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Peptidase_M24 PF00557.19 EIM92830.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 2 1 0 2 2 2 0 Metallopeptidase family M24 RNA_pol_Rpb4 PF03874.11 EIM92830.1 - 0.13 12.2 0.2 1.8 8.5 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EIM92830.1 - 0.14 11.6 0.0 0.89 9.0 0.0 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF2884 PF11101.3 EIM92830.1 - 0.15 11.4 0.8 0.2 10.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF533 PF04391.7 EIM92830.1 - 0.18 11.1 1.2 16 4.8 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF533) DEAD PF00270.24 EIM92831.1 - 4.6e-43 146.6 0.0 8.8e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIM92831.1 - 2e-21 75.6 0.0 3.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIM92831.1 - 3.9e-20 71.1 0.3 8.6e-20 70.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 EIM92831.1 - 0.12 12.5 0.3 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EIM92832.1 - 4.2e-09 35.9 19.1 9.4e-08 31.6 1.3 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat RRM_1 PF00076.17 EIM92837.1 - 8.8e-17 60.5 0.0 1.1e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM92837.1 - 1e-15 57.4 0.0 1.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM92837.1 - 4.3e-10 39.2 0.0 6.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIM92837.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain SMC_N PF02463.14 EIM92838.1 - 2.7e-62 209.8 45.8 1.3e-61 207.6 31.7 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIM92838.1 - 3.5e-26 91.5 0.9 3.8e-25 88.1 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIM92838.1 - 1.7e-13 51.1 8.8 3.3e-06 27.2 0.4 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIM92838.1 - 7.8e-06 25.3 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EIM92838.1 - 0.00089 18.5 21.7 0.00095 18.4 0.6 4.0 2 2 1 3 3 3 2 Reovirus sigma C capsid protein ABC_tran PF00005.22 EIM92838.1 - 0.25 11.6 0.0 0.25 11.6 0.0 6.1 4 2 0 4 4 4 0 ABC transporter DUF1212 PF06738.7 EIM92838.1 - 0.41 10.0 0.3 1.2 8.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Pkinase PF00069.20 EIM92839.1 - 8.1e-37 126.7 0.0 1.8e-36 125.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92839.1 - 1.3e-20 73.5 0.0 1.9e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92839.1 - 0.0031 16.5 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIM92839.1 - 0.016 14.9 0.0 0.064 12.9 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIM92839.1 - 0.029 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EIM92839.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EIM92839.1 - 0.18 10.8 0.0 0.4 9.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.1 EIM92840.1 - 9.4e-16 57.4 0.3 1.5e-06 28.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIM92840.1 - 4.7e-15 55.6 1.1 4e-07 30.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIM92840.1 - 3e-14 53.0 0.1 3.4e-08 33.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIM92840.1 - 3.6e-13 48.5 0.1 5.4e-05 22.7 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EIM92840.1 - 2.1e-10 39.7 0.2 2.8e-05 23.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Trehalase_Ca-bi PF07492.6 EIM92840.1 - 0.12 11.6 0.7 5.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain Aldo_ket_red PF00248.16 EIM92841.1 - 1.2e-45 155.5 0.0 1.4e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 EIM92842.1 - 4.4e-69 233.2 32.6 5e-69 233.0 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIM92842.1 - 2.2e-17 62.8 24.3 2.2e-17 62.8 16.8 2.7 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 EIM92842.1 - 4.5e-06 25.1 3.1 4.5e-06 25.1 2.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BatA PF07584.6 EIM92842.1 - 0.22 11.7 2.2 2.3 8.4 0.0 3.4 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal NfeD PF01957.13 EIM92842.1 - 0.22 11.6 0.0 0.22 11.6 0.0 4.0 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding NADH-u_ox-rdase PF10785.4 EIM92843.1 - 4.2 7.6 6.9 3.6 7.8 0.5 2.8 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF1115 PF06544.7 EIM92845.1 - 6.8e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Tannase PF07519.6 EIM92845.1 - 0.14 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase DUF726 PF05277.7 EIM92847.1 - 4.8e-120 400.5 0.4 6.9e-120 400.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EIM92847.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM92847.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIM92847.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HTH_23 PF13384.1 EIM92850.1 - 0.00012 21.6 1.9 0.00039 19.9 0.6 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIM92850.1 - 0.012 15.5 1.4 0.044 13.8 0.5 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HHH_5 PF14520.1 EIM92850.1 - 0.054 13.6 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain CENP-B_N PF04218.8 EIM92850.1 - 0.066 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SAM_2 PF07647.12 EIM92850.1 - 0.09 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mor PF08765.6 EIM92850.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Mor transcription activator family RNA_pol_A_CTD PF03118.10 EIM92851.1 - 0.012 14.9 1.1 0.12 11.8 0.8 2.4 1 1 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF2129 PF09902.4 EIM92851.1 - 0.047 13.4 0.1 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Abhydrolase_3 PF07859.8 EIM92853.1 - 5.8e-48 163.2 0.1 9.6e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIM92853.1 - 1.6e-12 46.7 0.0 6.1e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIM92853.1 - 4.8e-08 32.8 0.0 7.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M24 PF00557.19 EIM92854.1 - 3.7e-45 154.0 0.1 4.7e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.8 EIM92854.1 - 0.013 15.1 6.9 0.019 14.5 4.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NUP50 PF08911.6 EIM92854.1 - 0.022 15.1 0.8 0.046 14.0 0.5 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) TFIIF_alpha PF05793.7 EIM92854.1 - 0.36 9.1 11.5 0.54 8.5 8.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HSP90 PF00183.13 EIM92854.1 - 1.5 7.1 6.0 2.7 6.2 4.1 1.3 1 0 0 1 1 1 0 Hsp90 protein CAP PF00188.21 EIM92855.1 - 2.7e-21 76.3 2.5 3.4e-21 76.0 1.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EIM92857.1 - 7.7e-20 71.6 0.3 1.5e-19 70.7 0.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mito_fiss_reg PF05308.6 EIM92857.1 - 0.15 11.4 10.8 0.22 10.8 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EIM92857.1 - 1.2 8.3 16.4 0.86 8.8 10.1 1.5 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF659 PF04937.10 EIM92858.1 - 3e-07 30.0 0.0 6.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Fumerase PF05681.9 EIM92858.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) DUF1215 PF06744.7 EIM92858.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) Glyco_hydro_28 PF00295.12 EIM92860.1 - 5.3e-36 124.2 3.9 7.6e-36 123.6 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIM92860.1 - 0.019 14.7 16.7 0.018 14.7 5.6 3.1 1 1 2 3 3 3 0 Right handed beta helix region Patatin PF01734.17 EIM92861.1 - 5.4e-06 26.4 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase HisKA_3 PF07730.8 EIM92863.1 - 0.67 10.3 7.4 13 6.2 0.0 4.8 4 1 1 5 5 5 0 Histidine kinase NifQ PF04891.7 EIM92863.1 - 1.4 9.0 4.1 4.2 7.4 0.1 2.9 3 0 0 3 3 3 0 NifQ Flavin_Reduct PF01613.13 EIM92864.1 - 8.2e-14 51.7 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EIM92864.1 - 0.00012 21.7 0.1 0.0002 20.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 EIM92864.1 - 0.025 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ada_Zn_binding PF02805.11 EIM92865.1 - 1.5e-25 88.5 1.5 2.3e-25 87.9 1.0 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EIM92865.1 - 0.00049 19.8 0.0 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EIM92865.1 - 0.00097 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Glyco_transf_22 PF03901.12 EIM92867.1 - 6.9e-90 302.0 16.0 1e-89 301.4 11.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EIM92867.1 - 1.8e-05 24.6 9.0 1.8e-05 24.6 6.2 2.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1345 PF07077.6 EIM92867.1 - 2.3 7.7 12.9 0.23 10.9 0.5 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF1345) Fork_head PF00250.13 EIM92868.1 - 2.4e-20 72.3 0.0 4.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fork head domain MRP-L28 PF09812.4 EIM92868.1 - 0.16 11.8 4.1 0.086 12.6 1.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF4200 PF13863.1 EIM92868.1 - 0.25 11.3 9.2 0.73 9.7 6.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) WD40 PF00400.27 EIM92869.1 - 1.6e-81 265.4 26.5 2.3e-09 36.7 0.0 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 EIM92869.1 - 4.8e-41 139.6 0.0 7.6e-41 139.0 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain BBS2_Mid PF14783.1 EIM92869.1 - 0.02 14.6 0.1 11 5.8 0.0 5.2 8 0 0 8 8 8 0 Ciliary BBSome complex subunit 2, middle region zf-C2H2 PF00096.21 EIM92870.1 - 8.7e-13 47.8 9.9 3e-06 27.2 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM92870.1 - 2.5e-10 39.9 7.2 9.4e-05 22.4 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIM92870.1 - 3.9e-09 36.3 2.9 3.9e-09 36.3 2.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIM92870.1 - 0.0004 20.1 0.8 0.0004 20.1 0.5 2.9 3 1 0 3 3 3 1 C2H2-type zinc finger CHORD PF04968.7 EIM92870.1 - 0.047 13.9 4.7 2.3 8.5 1.1 2.1 1 1 1 2 2 2 0 CHORD IBR PF01485.16 EIM92870.1 - 0.06 13.2 0.1 0.06 13.2 0.1 1.9 1 1 1 2 2 2 0 IBR domain zf-C2H2_jaz PF12171.3 EIM92870.1 - 0.14 12.3 6.1 0.82 9.8 0.2 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIM92870.1 - 0.26 11.5 1.8 8.2 6.7 0.0 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC PF01530.13 EIM92870.1 - 6.2 6.6 11.0 0.2 11.3 1.3 2.6 2 1 0 2 2 2 0 Zinc finger, C2HC type zf-BED PF02892.10 EIM92870.1 - 7.2 6.4 9.3 20 5.0 3.3 2.3 2 0 0 2 2 2 0 BED zinc finger ZZ PF00569.12 EIM92871.1 - 1.7e-26 91.5 34.0 1.5e-09 37.2 3.6 3.3 3 0 0 3 3 3 3 Zinc finger, ZZ type Aminotran_4 PF01063.14 EIM92872.1 - 4.8e-16 58.9 0.0 7.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV S4_2 PF13275.1 EIM92872.1 - 0.0067 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 S4 domain ABM PF03992.11 EIM92873.1 - 4.3e-06 26.6 0.1 6.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3733 PF12534.3 EIM92873.1 - 0.13 11.5 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 SRP14 PF02290.10 EIM92874.1 - 1.6e-21 75.9 1.1 4.2e-21 74.6 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle 14kD protein gag_pre-integrs PF13976.1 EIM92874.1 - 0.044 13.4 0.5 0.078 12.6 0.2 1.6 1 1 0 1 1 1 0 GAG-pre-integrase domain DUF1682 PF07946.9 EIM92874.1 - 0.66 8.7 9.3 0.7 8.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TP_methylase PF00590.15 EIM92875.1 - 4.3e-40 137.6 0.5 7.7e-40 136.8 0.2 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EIM92875.1 - 3.4e-09 36.8 0.2 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIM92875.1 - 1.7e-07 30.4 2.6 9.7e-06 24.8 0.7 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIM92875.1 - 4.6e-05 22.3 0.0 9.1e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central zf-C4H2 PF10146.4 EIM92875.1 - 0.11 12.5 0.8 1 9.3 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein COX5A PF02284.11 EIM92876.1 - 2.9e-43 146.2 0.3 3.9e-43 145.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va CK2S PF15011.1 EIM92876.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate Homeobox PF00046.24 EIM92877.1 - 3.7e-16 58.4 7.3 8.5e-16 57.3 5.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIM92877.1 - 0.0026 17.4 0.1 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain NESP55 PF06390.7 EIM92878.1 - 0.0078 15.6 2.2 0.0084 15.5 1.5 1.1 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Bromodomain PF00439.20 EIM92881.1 - 5e-35 119.2 1.7 1.7e-16 59.9 0.2 2.5 2 0 0 2 2 2 2 Bromodomain TEX19 PF15553.1 EIM92881.1 - 0.84 9.4 4.6 0.21 11.4 0.5 2.0 2 0 0 2 2 2 0 Testis-expressed protein 19 PAT1 PF09770.4 EIM92881.1 - 2.2 6.3 14.1 3.2 5.8 9.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoplasmin PF03066.10 EIM92881.1 - 4.2 6.8 11.9 0.06 12.8 2.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin F-box-like PF12937.2 EIM92882.1 - 1.9e-09 37.0 0.0 5.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIM92882.1 - 1.5 8.5 3.6 18 5.1 0.5 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) FA_desaturase PF00487.19 EIM92883.1 - 1.9e-18 66.8 18.9 1.9e-18 66.8 13.1 2.1 3 0 0 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIM92883.1 - 1.9e-06 27.5 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CutC PF03932.9 EIM92884.1 - 3.7e-35 121.0 0.0 5.2e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 CutC family Nramp PF01566.13 EIM92885.1 - 6.6e-90 301.4 15.2 1.4e-89 300.4 10.6 1.5 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein TMEM154 PF15102.1 EIM92885.1 - 1.2 8.7 3.4 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family RNase_H2_suC PF08615.6 EIM92886.1 - 0.024 14.4 0.1 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop25 PF09805.4 EIM92886.1 - 0.027 14.5 5.8 0.073 13.1 4.0 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF815 PF05673.8 EIM92886.1 - 0.13 11.1 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_Ca_trans_C PF12424.3 EIM92886.1 - 0.22 11.8 2.8 0.5 10.7 0.1 3.0 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal Striatin PF08232.7 EIM92886.1 - 7.6 6.8 8.3 4 7.7 3.8 2.0 1 1 1 2 2 2 0 Striatin family Nucleoplasmin PF03066.10 EIM92886.1 - 8.6 5.8 9.9 0.28 10.6 2.1 1.9 2 0 0 2 2 2 0 Nucleoplasmin Myosin_head PF00063.16 EIM92887.1 - 4.8e-229 761.9 0.2 7.7e-229 761.2 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EIM92887.1 - 2.8e-45 154.0 0.0 4.8e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 EIM92887.1 - 3.7e-10 39.2 0.2 9.8e-10 37.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIM92887.1 - 3.1e-09 36.1 0.0 8.5e-09 34.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIM92887.1 - 8.2e-09 34.7 1.0 1.7e-08 33.7 0.7 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 EIM92887.1 - 2.3e-05 24.4 0.8 7.7e-05 22.8 0.6 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EIM92887.1 - 0.007 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SH3_4 PF06347.8 EIM92887.1 - 0.017 14.6 0.1 0.048 13.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Zeta_toxin PF06414.7 EIM92887.1 - 0.026 13.6 0.0 0.076 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIM92887.1 - 0.046 13.4 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 EIM92887.1 - 0.079 12.2 0.4 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EIM92887.1 - 0.11 13.3 0.0 0.32 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIM92887.1 - 0.19 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UNC45-central PF11701.3 EIM92888.1 - 2.4e-18 66.2 0.0 7.7e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EIM92888.1 - 0.0022 18.2 17.3 0.11 12.7 0.6 5.7 4 2 3 7 7 7 2 HEAT repeats Gcd10p PF04189.8 EIM92889.1 - 3.3e-73 246.4 0.0 8.5e-72 241.8 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family Co_AT_N PF12557.3 EIM92889.1 - 0.0055 16.5 0.5 0.0055 16.5 0.4 1.7 2 0 0 2 2 2 1 Cob(I)alamin adenosyltransferase N terminal PXA PF02194.10 EIM92890.1 - 3.3e-43 147.3 1.8 9.9e-43 145.8 0.0 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EIM92890.1 - 7.9e-29 100.0 0.2 7.9e-29 100.0 0.1 2.7 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EIM92890.1 - 9e-17 60.8 0.4 7.2e-16 57.9 0.0 2.7 4 0 0 4 4 4 1 PX domain RGS PF00615.14 EIM92890.1 - 1.3e-10 41.3 0.1 4.9e-10 39.5 0.1 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mito_carr PF00153.22 EIM92891.1 - 4.5e-54 180.1 0.6 1.3e-18 66.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.17 EIM92892.1 - 1.7e-126 422.2 0.0 2e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuclease_T2 PF00445.13 EIM92893.1 - 3.3e-41 141.0 0.2 5.3e-41 140.3 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.1 EIM92894.1 - 2.6e-19 68.4 0.0 3.8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 ACT domain zf-RING_2 PF13639.1 EIM92895.1 - 5.4e-13 48.5 6.5 5.4e-13 48.5 4.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIM92895.1 - 2.3e-11 43.6 1.1 2.3e-11 43.6 0.8 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIM92895.1 - 7.4e-07 28.7 5.0 7.4e-07 28.7 3.4 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIM92895.1 - 1.3e-06 27.9 3.6 1.3e-06 27.9 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIM92895.1 - 3.1e-06 27.1 2.4 3.1e-06 27.1 1.7 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EIM92895.1 - 3.2e-06 27.0 2.3 3.2e-06 27.0 1.6 2.9 3 0 0 3 3 3 1 zinc-finger zf-C3HC4 PF00097.20 EIM92895.1 - 4.1e-06 26.3 5.5 4.1e-06 26.3 3.8 2.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIM92895.1 - 1.1e-05 25.1 0.7 2.2e-05 24.2 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EIM92895.1 - 0.02 14.8 3.5 0.08 12.9 2.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-CSL PF05207.8 EIM92895.1 - 0.088 12.3 0.8 0.21 11.1 0.6 1.6 1 0 0 1 1 1 0 CSL zinc finger zf-RING_UBOX PF13445.1 EIM92895.1 - 0.1 12.3 5.5 0.36 10.5 0.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger HypA PF01155.14 EIM92895.1 - 0.13 11.9 4.4 3.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EIM92895.1 - 0.54 10.1 1.8 2.1 8.2 0.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger DNA_ligase_ZBD PF03119.11 EIM92895.1 - 0.68 9.6 6.4 1.1 9.0 1.3 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain OrfB_Zn_ribbon PF07282.6 EIM92895.1 - 2 8.1 4.1 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_1 PF00130.17 EIM92895.1 - 2.1 8.1 8.7 4.3 7.1 0.3 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EIM92895.1 - 3.7 6.8 11.4 21 4.4 0.2 3.8 3 1 1 4 4 4 0 Transcription factor zinc-finger PHD PF00628.24 EIM92895.1 - 6.6 6.5 17.4 0.59 9.8 3.8 2.7 3 0 0 3 3 3 0 PHD-finger DZR PF12773.2 EIM92895.1 - 7.5 6.4 9.3 4.6 7.1 0.3 2.8 2 1 1 3 3 3 0 Double zinc ribbon Asp PF00026.18 EIM92896.1 - 3.9e-46 157.7 11.3 1e-45 156.3 7.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM92896.1 - 4.6e-05 23.4 7.3 0.00067 19.6 3.8 3.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIM92896.1 - 0.00091 19.6 8.4 0.17 12.4 1.8 3.0 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.18 EIM92897.1 - 2.4e-44 151.8 25.0 5.2e-43 147.4 17.3 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIM92897.1 - 6.3e-07 29.4 7.5 3.7e-06 26.9 2.7 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DAO PF01266.19 EIM92898.1 - 1.6e-26 93.0 0.0 2.4e-26 92.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIM92898.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIM92898.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIM92898.1 - 0.007 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EIM92898.1 - 0.052 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 EIM92898.1 - 0.055 13.3 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.1 EIM92899.1 - 3.3e-39 135.0 0.0 3.8e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIM92899.1 - 2.5e-25 89.3 2.7 3e-25 89.0 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92899.1 - 2.4e-08 33.8 0.8 3.4e-08 33.3 0.6 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIM92899.1 - 0.00028 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EIM92899.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HAD PF12710.2 EIM92899.1 - 0.021 14.9 0.1 0.035 14.2 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DFP PF04127.10 EIM92899.1 - 0.083 12.5 1.3 0.4 10.2 1.5 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein p450 PF00067.17 EIM92900.1 - 1.5e-51 175.4 0.0 1.8e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF89 PF01937.14 EIM92901.1 - 4.6e-105 351.3 0.1 5.3e-105 351.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 L51_S25_CI-B8 PF05047.11 EIM92903.1 - 2.8e-12 46.1 0.1 4.3e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.15 EIM92903.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 LysR substrate binding domain RhoGAP PF00620.22 EIM92905.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.21 EIM92905.1 - 0.01 15.4 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 MSP (Major sperm protein) domain PapD-like PF14874.1 EIM92905.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like tRNA-synt_2 PF00152.15 EIM92906.1 - 3.2e-80 269.4 0.3 5.1e-80 268.7 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIM92906.1 - 3.1e-07 30.1 0.6 5.6e-07 29.3 0.4 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIM92906.1 - 0.0025 17.0 1.5 0.74 8.9 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) HTH_39 PF14090.1 EIM92906.1 - 0.12 11.8 0.5 2.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HemY_N PF07219.8 EIM92907.1 - 0.085 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF3328 PF11807.3 EIM92908.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) GRA6 PF05084.8 EIM92908.1 - 0.064 12.7 0.2 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Peptidase_M56 PF05569.6 EIM92908.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Amidohydro_1 PF01979.15 EIM92912.1 - 9.7e-18 64.9 0.5 4.1e-17 62.8 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIM92912.1 - 3.3e-09 36.4 0.0 1.2e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIM92912.1 - 2.5e-05 24.4 4.8 2.5e-05 24.4 3.3 2.8 2 1 1 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EIM92912.1 - 0.00047 19.5 0.3 0.092 11.9 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family MR_MLE_C PF13378.1 EIM92912.1 - 0.39 10.7 2.6 5.1 7.1 0.0 3.4 3 1 0 4 4 4 0 Enolase C-terminal domain-like Histone PF00125.19 EIM92913.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIM92913.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIM92913.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIM92913.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIM92913.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIM92913.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.12 EIM92914.1 - 9.1e-33 113.5 0.0 3e-32 111.8 0.0 1.8 1 1 0 1 1 1 1 RibD C-terminal domain YTH PF04146.10 EIM92915.1 - 9.6e-44 148.3 0.0 2.1e-41 140.8 0.0 3.0 3 0 0 3 3 3 1 YT521-B-like domain RRM_1 PF00076.17 EIM92915.1 - 7.9e-06 25.4 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIM92915.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIM92915.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 EIM92916.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like Glyco_hydro_28 PF00295.12 EIM92917.1 - 8.5e-43 146.5 11.2 8.5e-43 146.5 5.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 NTF2 PF02136.15 EIM92918.1 - 3.8e-13 49.8 0.0 4.6e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EIM92918.1 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF1658 PF07871.6 EIM92918.1 - 0.25 11.0 1.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Pkinase PF00069.20 EIM92919.1 - 7.3e-77 258.0 0.0 9.9e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIM92919.1 - 6.5e-43 146.6 0.0 9.5e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIM92919.1 - 1.7e-06 27.1 0.0 3.9e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIM92919.1 - 0.0001 21.7 0.1 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 EIM92919.1 - 0.00037 20.6 1.1 0.00059 19.9 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) APH PF01636.18 EIM92919.1 - 0.0021 17.8 1.4 0.23 11.1 0.3 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family YukC PF10140.4 EIM92919.1 - 0.078 11.5 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CBM_21 PF03370.8 EIM92921.1 - 3.2e-22 78.6 0.0 1.1e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit F-box-like PF12937.2 EIM92922.1 - 4.3e-10 39.1 1.7 4.3e-10 39.1 1.2 2.5 3 0 0 3 3 3 1 F-box-like Heme_oxygenase PF01126.15 EIM92923.1 - 0.057 12.9 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase Nnf1 PF03980.9 EIM92923.1 - 0.067 13.1 5.2 0.32 11.0 0.2 2.6 2 1 0 2 2 2 0 Nnf1 SLX9 PF15341.1 EIM92923.1 - 0.77 10.2 4.4 1.7 9.1 3.0 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 APG6 PF04111.7 EIM92923.1 - 1.2 8.1 10.0 2.9 6.8 6.9 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Mto2_bdg PF12808.2 EIM92923.1 - 1.6 8.8 9.3 0.16 12.0 1.4 2.7 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region UPF0242 PF06785.6 EIM92923.1 - 4.6 5.8 7.5 7.3 5.1 5.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) FlxA PF14282.1 EIM92923.1 - 5.7 6.9 9.0 12 5.9 5.6 2.0 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.13 EIM92924.1 - 2.2e-23 82.4 0.3 4.8e-23 81.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIM92924.1 - 0.00045 20.0 13.2 0.00085 19.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 EIM92925.1 - 7.2e-81 271.4 0.0 2e-80 270.0 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Spc7 PF08317.6 EIM92926.1 - 1.8e-44 151.7 9.1 1.8e-44 151.7 6.3 1.9 3 0 0 3 3 3 1 Spc7 kinetochore protein DUF1664 PF07889.7 EIM92926.1 - 0.028 14.2 0.9 6.7 6.5 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7_C2 PF15577.1 EIM92926.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 APG6 PF04111.7 EIM92926.1 - 0.22 10.5 14.1 0.47 9.4 9.7 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EIM92926.1 - 1.3 8.9 12.2 0.32 10.8 0.9 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 EIM92926.1 - 2.5 7.8 7.2 0.53 10.0 0.4 2.8 2 1 1 3 3 3 0 Laminin Domain II Fib_alpha PF08702.5 EIM92926.1 - 4.4 7.4 7.3 1.9 8.6 1.7 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 EIM92926.1 - 4.5 5.5 14.0 0.35 9.2 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Methyltrans_Mon PF14314.1 EIM92927.1 - 0.35 8.6 2.3 0.51 8.1 1.6 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase DIE2_ALG10 PF04922.7 EIM92928.1 - 3e-94 316.1 12.4 4.3e-94 315.6 8.6 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family RhodobacterPufX PF11511.3 EIM92928.1 - 0.049 13.0 1.8 0.14 11.6 1.2 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX OPT PF03169.10 EIM92929.1 - 3.3e-180 600.5 54.5 4e-180 600.3 37.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.14 EIM92930.1 - 9.8e-44 149.6 0.0 1.3e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIM92930.1 - 1e-28 100.4 0.0 1.9e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIM92930.1 - 8.2e-05 21.6 0.2 0.0082 15.0 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIM92930.1 - 0.0027 17.6 0.1 0.0084 16.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIM92930.1 - 0.0073 15.2 0.8 0.081 11.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EIM92930.1 - 0.0076 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF4401 PF14351.1 EIM92931.1 - 0.0088 15.0 9.9 0.014 14.4 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF2231 PF09990.4 EIM92931.1 - 0.028 14.7 8.7 0.21 11.9 1.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Esterase_phd PF10503.4 EIM92932.1 - 1.4e-23 83.3 0.9 2e-23 82.8 0.6 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EIM92932.1 - 1.9e-11 43.4 8.6 9.1e-11 41.2 6.0 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EIM92932.1 - 5.3e-09 35.6 1.8 7.6e-09 35.1 1.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIM92932.1 - 0.0009 19.0 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM92932.1 - 0.012 15.1 0.4 0.022 14.3 0.2 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIM92932.1 - 0.021 14.7 0.1 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EIM92932.1 - 0.041 13.2 0.3 0.059 12.7 0.2 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 EIM92932.1 - 0.054 13.0 0.1 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EIM92932.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIM92932.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TauD PF02668.11 EIM92933.1 - 2.3e-52 178.2 0.5 2.8e-52 177.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_3 PF07732.10 EIM92933.1 - 0.1 12.3 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Multicopper oxidase OPT PF03169.10 EIM92934.1 - 2e-171 571.6 56.6 2.2e-171 571.4 39.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Prp19 PF08606.6 EIM92935.1 - 4.5e-29 99.9 1.7 7.6e-29 99.2 1.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EIM92935.1 - 1.1e-15 56.7 5.7 0.0003 20.5 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat U-box PF04564.10 EIM92935.1 - 1.7e-06 27.9 0.0 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 EIM92935.1 - 9.6e-06 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 EIM92935.1 - 0.0022 16.3 0.0 0.014 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) zf-C2H2 PF00096.21 EIM92936.1 - 1.4e-07 31.3 4.1 0.0098 16.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIM92936.1 - 4.9e-07 29.6 3.5 0.0066 16.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIM92936.1 - 0.0001 22.3 0.5 0.11 12.5 0.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EIM92936.1 - 0.001 19.2 0.9 0.0052 17.0 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 EIM92936.1 - 0.07 12.8 0.2 0.19 11.4 0.2 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Abhydrolase_6 PF12697.2 EIM92937.1 - 1.2e-12 48.1 1.0 4.1e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIM92937.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIM92937.1 - 0.003 17.1 0.0 0.057 12.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIM92937.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 EIM92937.1 - 0.03 13.9 0.5 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.13 EIM92937.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF900 PF05990.7 EIM92937.1 - 0.16 11.2 0.0 0.45 9.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 EIM92937.1 - 0.21 11.0 0.1 0.48 9.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase Myb_DNA-bind_6 PF13921.1 EIM92938.1 - 5e-41 138.6 11.4 4e-17 62.0 0.2 4.3 2 2 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIM92938.1 - 1.5e-38 130.5 11.5 2.6e-12 46.5 0.8 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain zf-C2H2 PF00096.21 EIM92938.1 - 0.0035 17.5 6.8 0.0091 16.2 1.5 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 EIM92938.1 - 0.0074 16.3 5.1 0.11 12.5 0.4 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EIM92938.1 - 0.016 15.4 0.4 0.016 15.4 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIM92938.1 - 0.019 14.8 0.9 8.2 6.4 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Rap1_C PF11626.3 EIM92938.1 - 0.071 13.0 5.4 4.9 7.1 0.2 3.3 1 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-H2C2_2 PF13465.1 EIM92938.1 - 0.69 10.3 15.2 0.22 11.9 2.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain WD40 PF00400.27 EIM92939.1 - 6e-42 140.0 9.5 4.3e-09 35.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIM92939.1 - 0.00048 19.6 0.0 0.012 15.0 0.0 2.5 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 EIM92939.1 - 0.012 13.9 0.0 3 6.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.3 EIM92939.1 - 0.049 11.7 0.3 0.73 7.8 0.2 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 MCM PF00493.18 EIM92942.1 - 9.8e-128 425.6 0.1 1.5e-127 424.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIM92942.1 - 1.6e-22 80.2 0.0 4.2e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIM92942.1 - 1.7e-08 33.8 0.5 1.1e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIM92942.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIM92942.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Nucleoplasmin PF03066.10 EIM92942.1 - 0.034 13.6 2.9 0.071 12.6 2.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 EIM92942.1 - 0.055 13.5 6.0 0.11 12.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) AAA_5 PF07728.9 EIM92942.1 - 0.082 12.6 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3500 PF12006.3 EIM92943.1 - 8.7e-83 277.8 0.0 1e-82 277.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) TTL PF03133.10 EIM92945.1 - 1.1e-43 149.2 0.0 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EIM92945.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Thioredoxin PF00085.15 EIM92946.1 - 5.7e-27 93.4 0.0 6.4e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EIM92946.1 - 1.4e-08 34.3 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIM92946.1 - 1.6e-06 28.2 0.1 2e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIM92946.1 - 3e-06 27.2 0.0 5.5e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EIM92946.1 - 0.00015 21.3 0.1 0.0091 15.5 0.1 1.9 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.19 EIM92946.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF2847 PF11009.3 EIM92946.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AhpC-TSA PF00578.16 EIM92946.1 - 0.036 13.7 0.2 0.16 11.6 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family KaiB PF07689.7 EIM92946.1 - 0.051 13.0 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiB domain Thioredoxin_7 PF13899.1 EIM92946.1 - 0.056 13.4 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like BLVR PF06375.6 EIM92947.1 - 0.0001 22.1 2.3 0.11 12.3 1.1 2.3 2 0 0 2 2 2 2 Bovine leukaemia virus receptor (BLVR) TPR_11 PF13414.1 EIM92947.1 - 0.041 13.5 0.0 0.71 9.5 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.1 EIM92947.1 - 0.064 13.1 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EIM92948.1 - 1.4e-11 44.6 0.5 2.4e-11 43.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIM92948.1 - 0.00044 20.1 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIM92948.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIM92948.1 - 0.021 14.4 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 KR domain CDC50 PF03381.10 EIM92949.1 - 4.3e-83 278.6 0.0 5.3e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Baculo_E56 PF04639.7 EIM92951.1 - 0.016 13.8 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope LRR_7 PF13504.1 EIM92951.1 - 0.032 14.3 3.5 12 6.6 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 EIM92951.1 - 1.1 9.0 3.9 6.9 6.5 0.0 3.2 3 1 0 3 3 3 0 Leucine rich repeat Zip PF02535.17 EIM92952.1 - 0.033 13.2 0.5 0.16 10.9 0.0 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter PEMT PF04191.8 EIM92952.1 - 1.3 9.1 6.7 0.25 11.4 0.7 2.8 3 1 0 3 3 3 0 Phospholipid methyltransferase E1_DerP2_DerF2 PF02221.10 EIM92953.1 - 1.8e-23 83.2 0.1 2.3e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIM92953.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.4 1 1 0 1 1 1 1 ML-like domain RNase_T PF00929.19 EIM92954.1 - 7.9e-22 78.2 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Ipi1_N PF12333.3 EIM92956.1 - 4.9e-13 48.9 0.1 1.5e-10 40.9 0.0 4.2 2 1 2 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 EIM92956.1 - 0.002 18.3 0.0 0.0077 16.4 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats Cnd1 PF12717.2 EIM92956.1 - 0.034 13.9 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Tuberin PF03542.11 EIM92956.1 - 0.041 12.9 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Tuberin HEAT_EZ PF13513.1 EIM92956.1 - 0.19 12.2 1.0 1.1 9.8 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat DNA_pol_A_exo1 PF01612.15 EIM92958.1 - 5e-11 42.4 0.0 5.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DPBB_1 PF03330.13 EIM92959.1 - 2.8e-08 33.6 0.2 9e-08 32.0 0.1 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Hamartin PF04388.7 EIM92959.1 - 0.23 10.1 12.6 0.22 10.1 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein JAB PF01398.16 EIM92960.1 - 2.5e-14 52.9 0.0 5.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_efflux PF01545.16 EIM92961.1 - 1.5e-75 253.9 6.0 4.9e-75 252.2 4.2 1.7 1 1 0 1 1 1 1 Cation efflux family MerC PF03203.9 EIM92961.1 - 3.1 8.1 11.3 4.1 7.7 0.4 3.0 2 1 0 3 3 3 0 MerC mercury resistance protein Med5 PF08689.5 EIM92962.1 - 1e-21 76.4 0.3 1e-21 76.4 0.2 2.0 3 0 0 3 3 3 1 Mediator complex subunit Med5 Cys_Met_Meta_PP PF01053.15 EIM92963.1 - 1.5e-26 92.5 0.0 2.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIM92963.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II F-box-like PF12937.2 EIM92964.1 - 3e-08 33.2 4.4 9.2e-08 31.6 0.7 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIM92964.1 - 5.4e-08 32.2 2.0 5.4e-08 32.2 1.4 2.3 2 0 0 2 2 2 1 F-box domain Pex14_N PF04695.8 EIM92965.1 - 2.2e-25 89.2 0.1 2.2e-25 89.2 0.0 6.6 6 1 0 6 6 6 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.15 EIM92965.1 - 3.2e-17 61.7 0.7 7.7e-17 60.5 0.5 1.7 1 0 0 1 1 1 1 GRIP domain Viral_protease PF08715.5 EIM92965.1 - 0.22 10.5 0.2 12 4.8 0.1 2.2 2 0 0 2 2 2 0 Papain like viral protease NPV_P10 PF05531.7 EIM92965.1 - 0.28 11.4 36.6 0.57 10.4 0.9 8.5 5 3 2 7 7 7 0 Nucleopolyhedrovirus P10 protein GTP_EFTU PF00009.22 EIM92966.1 - 9.4e-59 198.0 0.1 1.4e-58 197.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIM92966.1 - 2.9e-28 97.9 0.1 1.7e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIM92966.1 - 5.6e-15 55.2 3.9 6.4e-15 55.0 1.9 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIM92966.1 - 2.2e-05 24.3 0.1 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIM92966.1 - 0.0056 17.1 0.0 0.0097 16.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EIM92966.1 - 0.031 13.9 0.5 0.074 12.6 0.4 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 cobW PF02492.14 EIM92966.1 - 0.04 13.3 0.3 0.073 12.5 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIM92966.1 - 0.059 12.8 0.5 9.7 5.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 EIM92966.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding SPRY PF00622.23 EIM92967.1 - 3e-19 69.3 0.1 4.6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Mito_carr PF00153.22 EIM92968.1 - 1.2e-58 194.8 0.5 1.9e-18 65.9 0.0 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EIM92969.1 - 2.7e-15 56.1 0.0 4.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EIM92969.1 - 1.5e-10 40.5 6.9 1.5e-10 40.5 4.8 1.8 2 0 0 2 2 2 1 SNARE domain SlyX PF04102.7 EIM92969.1 - 9.4 6.6 10.7 3.1 8.2 0.1 3.2 2 1 1 3 3 3 0 SlyX CBS PF00571.23 EIM92970.1 - 4.2e-32 109.6 2.4 4.2e-13 48.8 0.1 4.4 4 1 0 4 4 4 4 CBS domain Pil1 PF13805.1 EIM92971.1 - 2e-19 69.8 0.0 5.1e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Eisosome component PIL1 IF4E PF01652.13 EIM92972.1 - 1.3e-47 161.3 0.0 1.7e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3251 PF11622.3 EIM92973.1 - 0.0039 16.6 0.2 0.009 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) ABC1 PF03109.11 EIM92973.1 - 0.0057 16.6 0.2 0.0085 16.0 0.1 1.3 1 0 0 1 1 1 1 ABC1 family SMN PF06003.7 EIM92975.1 - 0.00018 20.7 3.8 0.00057 19.0 2.4 1.8 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 EIM92975.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain PWWP PF00855.12 EIM92975.1 - 0.016 15.4 1.1 0.072 13.3 0.7 2.1 1 1 0 1 1 1 0 PWWP domain Relaxase PF03432.9 EIM92975.1 - 0.041 13.2 3.3 0.059 12.7 2.3 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain RIO1 PF01163.17 EIM92976.1 - 9.2e-48 162.0 0.1 1.3e-47 161.6 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EIM92976.1 - 3.6e-34 116.6 0.1 8.8e-34 115.4 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EIM92976.1 - 3.4e-11 43.3 0.3 0.00012 21.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIM92976.1 - 2.5e-07 29.9 0.0 3.4e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.19 EIM92977.1 - 9.9e-15 54.3 0.1 1.5e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIM92977.1 - 6.1e-05 23.1 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIM92977.1 - 0.00023 20.8 0.0 0.00048 19.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIM92977.1 - 0.00032 20.7 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIM92977.1 - 0.00047 20.1 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short PF00106.20 EIM92978.1 - 4.9e-19 68.8 0.1 7.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIM92978.1 - 6.7e-12 45.4 0.1 1.1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 KR domain ESSS PF10183.4 EIM92979.1 - 7.5e-26 90.5 0.0 9.7e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.14 EIM92980.1 - 1.3e-40 137.8 0.1 1.6e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EIM92980.1 - 8e-05 22.1 0.1 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EIM92980.1 - 0.0004 20.0 0.2 0.00066 19.3 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MFS_1 PF07690.11 EIM92981.1 - 2.4e-21 75.8 51.4 2.6e-11 42.8 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 EIM92982.1 - 1.2e-09 38.1 0.0 6.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain HATPase_c_3 PF13589.1 EIM92982.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_61 PF03443.9 EIM92983.1 - 6.8e-56 189.5 0.1 1.1e-55 188.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cu-oxidase PF00394.17 EIM92984.1 - 1.1e-41 142.3 0.5 8e-40 136.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIM92984.1 - 4.3e-35 120.2 1.3 8.3e-33 112.8 0.3 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIM92984.1 - 3.5e-32 110.5 2.4 1.1e-28 99.2 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Ribosomal_L10 PF00466.15 EIM92985.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L10