# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- GCP_C_terminal PF04130.13 KEY63800.1 - 1.1e-98 330.5 1.4 1.1e-98 330.5 1.4 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEY63800.1 - 3.9e-84 282.9 0.0 6.6e-84 282.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal SAGA-Tad1 PF12767.7 KEY63801.1 - 3.6e-62 210.2 0.0 4.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ClpS PF02617.17 KEY63801.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS cNMP_binding PF00027.29 KEY63803.1 - 1.3e-39 134.1 0.0 8.3e-22 77.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 KEY63804.1 - 4.4e-57 193.1 0.7 5.1e-57 192.9 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF484 PF04340.12 KEY63804.1 - 0.031 14.0 0.3 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 HABP4_PAI-RBP1 PF04774.15 KEY63805.1 - 0.0016 19.3 0.0 0.0021 18.9 0.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family SH2_2 PF14633.6 KEY63806.1 - 2.4e-83 278.8 0.0 6.7e-83 277.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KEY63806.1 - 9.8e-37 125.9 2.8 3.5e-36 124.1 2.8 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KEY63806.1 - 8e-31 106.5 0.0 1.9e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KEY63806.1 - 6.7e-30 103.9 0.0 3.7e-29 101.5 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KEY63806.1 - 6.9e-22 77.8 29.2 6.9e-22 77.8 29.2 6.8 4 1 3 7 7 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KEY63806.1 - 1.9e-07 31.9 0.8 6.4e-06 27.0 0.8 3.4 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KEY63806.1 - 1.9e-05 24.6 0.0 5.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 KEY63806.1 - 0.0001 22.5 0.1 0.00025 21.3 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 KEY63806.1 - 0.0031 17.7 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.19 KEY63806.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain PSD4 PF07631.11 KEY63806.1 - 1 9.9 4.5 6.4 7.3 0.0 3.9 3 1 0 4 4 3 0 Protein of unknown function (DUF1592) Tex_N PF09371.10 KEY63806.1 - 1.7 8.3 6.6 1.7 8.3 0.6 3.3 3 1 0 3 3 3 0 Tex-like protein N-terminal domain Pkinase PF00069.25 KEY63807.1 - 7.9e-65 218.8 0.0 1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY63807.1 - 8.3e-39 133.4 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY63807.1 - 0.00031 19.6 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEY63807.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY63807.1 - 0.039 12.9 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KEY63807.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HAD_2 PF13419.6 KEY63808.1 - 1.8e-13 51.0 0.0 4.4e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY63808.1 - 1.6e-12 48.2 0.0 1.7e-08 35.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY63808.1 - 2.8e-07 30.5 0.4 5.4e-07 29.6 0.4 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KEY63808.1 - 5.9e-05 23.6 0.1 0.0014 19.0 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KEY63808.1 - 0.058 13.0 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.6 KEY63809.1 - 9.8e-26 90.4 7.8 9.8e-26 90.4 7.8 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KEY63809.1 - 0.0005 18.7 4.1 0.0005 18.7 4.1 2.8 3 1 0 3 3 3 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 KEY63809.1 - 0.036 13.9 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Phage_TAC_8 PF10666.9 KEY63809.1 - 0.059 13.7 0.2 0.18 12.1 0.2 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 ALMT PF11744.8 KEY63809.1 - 0.094 11.5 14.4 0.36 9.6 10.1 3.4 3 1 0 3 3 3 0 Aluminium activated malate transporter FUSC-like PF12805.7 KEY63809.1 - 0.16 11.0 3.7 4.4 6.3 0.3 2.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DNA_pol_E_B PF04042.16 KEY63810.1 - 2.2e-63 213.4 0.0 3.2e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HET PF06985.11 KEY63813.1 - 2.1e-26 93.0 0.2 3.7e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.20 KEY63814.1 - 8.9e-37 127.1 0.0 1.1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Na_H_Exchanger PF00999.21 KEY63815.1 - 1e-39 136.5 20.1 1.6e-39 135.8 20.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KEY63815.1 - 0.00084 19.4 0.1 0.00084 19.4 0.1 3.5 5 0 0 5 5 5 1 YrhC-like protein Sugar_tr PF00083.24 KEY63816.1 - 5.1e-78 263.0 24.7 5.8e-78 262.8 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY63816.1 - 2.9e-22 79.1 35.4 1.5e-20 73.5 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY63816.1 - 4.3e-08 32.1 15.3 3.1e-07 29.3 1.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Gate PF07670.14 KEY63816.1 - 0.0033 17.7 0.0 5.1 7.4 0.3 3.7 2 2 1 3 3 3 2 Nucleoside recognition DUF2645 PF10840.8 KEY63816.1 - 0.03 15.0 1.0 0.2 12.3 1.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) MBOAT PF03062.19 KEY63817.1 - 1.2e-39 136.7 10.2 3.4e-38 131.9 5.6 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family HSP90 PF00183.18 KEY63818.1 - 1.5e-223 743.4 27.7 1.9e-223 743.1 27.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KEY63818.1 - 5.9e-16 59.0 0.1 1.1e-15 58.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEY63818.1 - 8.8e-10 38.5 0.1 2.7e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KEY63818.1 - 0.012 15.6 2.1 0.23 11.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.9 KEY63818.1 - 0.39 10.7 3.9 0.18 11.8 0.4 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Cofac_haem_bdg PF04187.13 KEY63818.1 - 0.64 10.0 2.2 1.2 9.1 0.1 2.4 2 1 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN Glyco_hydro_26 PF02156.15 KEY63819.1 - 4.2e-85 285.9 5.8 5.3e-85 285.6 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KEY63819.1 - 1.1e-21 77.3 0.6 3.9e-21 75.6 0.6 1.9 1 1 0 1 1 1 1 Carbohydrate binding module (family 35) Vps5 PF09325.10 KEY63821.1 - 2.2e-85 286.0 7.1 2.2e-85 286.0 7.1 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KEY63821.1 - 1.5e-22 79.7 1.2 2.5e-22 79.0 0.1 2.0 2 1 0 2 2 2 1 PX domain BAR_3 PF16746.5 KEY63821.1 - 0.0012 18.6 8.5 0.11 12.2 3.5 2.7 1 1 1 2 2 2 2 BAR domain of APPL family DUF713 PF05218.14 KEY63821.1 - 0.092 12.5 4.4 0.083 12.6 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF713) BAR_2 PF10455.9 KEY63821.1 - 0.27 10.3 7.1 0.64 9.1 6.6 1.9 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KEY63821.1 - 0.41 10.3 10.6 1 9.0 10.6 1.7 1 1 0 1 1 1 0 BAR domain TFIID_NTD2 PF04494.15 KEY63822.1 - 8.1e-41 139.3 0.1 1.1e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KEY63822.1 - 9.1e-38 127.6 15.5 8.4e-08 32.8 0.2 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY63822.1 - 8.4e-14 51.6 0.1 0.058 13.7 0.0 5.3 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY63822.1 - 6.7e-05 22.9 0.0 0.0021 18.0 0.0 3.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEY63822.1 - 0.00022 20.0 0.5 2.2 6.8 0.1 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEY63822.1 - 0.00045 19.1 0.0 0.22 10.2 0.0 3.3 3 1 1 4 4 4 1 Nup133 N terminal like LisH PF08513.11 KEY63822.1 - 0.003 17.4 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KEY63822.1 - 0.0057 15.6 0.5 0.79 8.6 0.0 3.6 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KEY63822.1 - 0.049 12.9 0.0 3.7 6.7 0.0 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 KEY63822.1 - 0.097 12.0 0.3 8.3 5.6 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Med11 PF10280.9 KEY63823.1 - 3.2e-46 157.2 0.0 3.7e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Ytp1 PF10355.9 KEY63826.1 - 7.8e-68 228.7 18.4 7.8e-68 228.7 18.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KEY63826.1 - 7.1e-31 106.1 2.1 7.1e-31 106.1 2.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) zf-IS66 PF13005.7 KEY63828.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 CpXC PF14353.6 KEY63828.1 - 0.15 12.1 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 CpXC protein MPC PF03650.13 KEY63833.1 - 1.8e-34 118.2 0.0 2.2e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers OGG_N PF07934.12 KEY63834.1 - 1e-35 122.4 0.0 1.8e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KEY63834.1 - 8.6e-18 64.8 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEY63834.1 - 5.5e-05 22.8 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 KEY63835.1 - 1.6e-28 98.3 1.0 1.8e-10 40.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY63835.1 - 0.0015 18.4 0.3 2.6 7.9 0.0 3.6 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEY63835.1 - 0.079 13.0 0.0 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S13_N PF08069.12 KEY63836.1 - 1.4e-28 98.7 0.1 3.1e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KEY63836.1 - 2e-11 43.9 0.4 4.8e-11 42.7 0.5 1.6 1 1 1 2 2 2 1 Ribosomal protein S15 PAX PF00292.18 KEY63836.1 - 0.061 13.2 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain DUF3860 PF12976.7 KEY63836.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Dpy-30 PF05186.13 KEY63837.1 - 6e-13 48.3 0.0 8e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 KEY63838.1 - 5.3e-22 77.9 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain p450 PF00067.22 KEY63839.1 - 1.8e-67 228.1 0.0 2.2e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KEY63840.1 - 5.3e-27 94.5 0.0 8.5e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KEY63840.1 - 0.00016 22.3 0.0 0.0016 19.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY63840.1 - 0.0009 19.9 0.0 0.0022 18.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF4423 PF14394.6 KEY63840.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Methyltransf_4 PF02390.17 KEY63840.1 - 0.041 13.3 0.1 0.097 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 KEY63840.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_47 PF16221.5 KEY63840.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix FAD_binding_3 PF01494.19 KEY63841.1 - 1.2e-17 64.3 0.1 3.1e-08 33.2 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY63841.1 - 1.7e-05 25.0 0.3 4.4e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY63841.1 - 3.4e-05 23.6 1.1 8e-05 22.4 0.2 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY63841.1 - 0.018 14.3 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KEY63841.1 - 0.032 13.3 0.2 0.054 12.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEY63841.1 - 0.05 14.2 0.0 0.55 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY63841.1 - 0.094 11.9 0.0 2.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.6 KEY63842.1 - 8.7e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY63842.1 - 1.9e-10 40.9 0.0 8.2e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY63842.1 - 3.6e-10 40.0 0.0 6.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY63842.1 - 1.8e-08 34.4 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY63842.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY63842.1 - 7.3e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY63842.1 - 0.063 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Phage_DNA_bind PF02303.17 KEY63842.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-destabilising protein Tri3 PF07428.11 KEY63843.1 - 9.9e-07 28.0 0.0 0.0039 16.2 0.0 2.1 1 1 1 2 2 2 2 15-O-acetyltransferase Tri3 SnoaL_2 PF12680.7 KEY63844.1 - 0.022 15.4 0.4 0.034 14.8 0.4 1.3 1 0 0 1 1 1 0 SnoaL-like domain Zn_clus PF00172.18 KEY63845.1 - 2.9e-10 40.1 6.8 2.9e-10 40.1 6.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 KEY63845.1 - 6.7e-05 22.5 0.5 0.00012 21.6 0.5 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Epimerase PF01370.21 KEY63846.1 - 1.9e-06 27.5 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY63846.1 - 0.00092 18.7 0.0 0.002 17.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEY63846.1 - 0.0053 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEY63847.1 - 4.6e-13 49.1 0.5 6.3e-13 48.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY63847.1 - 5.7e-13 49.0 0.6 6.9e-13 48.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KEY63847.1 - 1.7e-06 28.1 0.8 3.2e-06 27.1 0.8 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY63847.1 - 4e-06 26.9 0.4 5.9e-06 26.3 0.4 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KEY63847.1 - 2e-05 24.2 1.8 5.3e-05 22.9 1.8 1.8 1 1 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KEY63847.1 - 0.00016 22.2 0.7 0.0046 17.5 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KEY63847.1 - 0.0014 18.2 0.3 0.0021 17.5 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY63847.1 - 0.0032 16.9 0.2 0.0042 16.5 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase SnoaL_2 PF12680.7 KEY63847.1 - 0.013 16.2 0.1 0.033 14.8 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain ADH_zinc_N PF00107.26 KEY63847.1 - 0.032 14.2 0.2 0.067 13.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KEY63847.1 - 0.091 13.2 0.3 0.22 12.0 0.3 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KEY63847.1 - 0.1 12.7 1.3 0.22 11.7 1.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MOSC PF03473.17 KEY63848.1 - 2.1e-25 89.3 0.0 5.2e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 KEY63848.1 - 8.2e-10 38.5 1.3 1.8e-09 37.4 1.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 KEY63848.1 - 5.1e-09 35.8 0.1 1.1e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 KEY63848.1 - 4.2e-05 24.1 0.0 0.00045 20.8 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEY63848.1 - 0.0023 18.0 0.5 0.28 11.3 0.1 2.5 1 1 0 2 2 2 2 Ferric reductase NAD binding domain RRP7 PF12923.7 KEY63849.1 - 4.9e-30 104.1 16.4 8.6e-30 103.3 16.4 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KEY63849.1 - 1.4e-13 51.0 0.0 3.9e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF92 PF01940.16 KEY63850.1 - 3e-74 249.4 0.9 2.8e-73 246.2 0.9 2.1 1 1 0 1 1 1 1 Integral membrane protein DUF92 ADIP PF11559.8 KEY63850.1 - 1.8e-33 115.8 4.1 1.8e-33 115.8 4.1 3.3 4 0 0 4 4 3 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KEY63850.1 - 0.006 16.5 8.7 0.15 12.1 3.5 3.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 KEY63850.1 - 0.24 9.3 1.0 0.39 8.6 1.0 1.3 1 0 0 1 1 1 0 Prominin DUF641 PF04859.12 KEY63850.1 - 0.28 11.5 7.0 2.6 8.4 3.2 3.0 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) DUF5094 PF17015.5 KEY63850.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5094) ENOD93 PF03386.14 KEY63850.1 - 0.92 9.4 3.2 3 7.8 3.2 1.8 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein BRE1 PF08647.11 KEY63850.1 - 1 9.5 8.3 4.4 7.4 8.3 2.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Golgin_A5 PF09787.9 KEY63850.1 - 1.7 8.0 14.5 0.016 14.7 4.7 2.5 3 0 0 3 3 3 0 Golgin subfamily A member 5 ZapB PF06005.12 KEY63850.1 - 2.3 8.7 6.2 46 4.5 2.0 3.5 2 1 0 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KEY63850.1 - 8.2 5.2 16.6 0.022 13.7 6.0 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein EHN PF06441.12 KEY63851.1 - 9.1e-23 80.7 0.6 3.6e-22 78.8 0.2 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus WSC PF01822.19 KEY63851.1 - 9.7e-14 51.3 7.0 2.1e-13 50.3 7.0 1.6 1 0 0 1 1 1 1 WSC domain Abhydrolase_1 PF00561.20 KEY63851.1 - 1.7e-07 31.2 0.3 1.4e-06 28.2 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY63851.1 - 0.0011 19.7 6.8 0.0017 19.0 4.9 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DDE_Tnp_1_7 PF13843.6 KEY63853.1 - 0.027 13.8 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 CHAT PF12770.7 KEY63854.1 - 1.6e-28 99.9 0.0 1.2e-27 97.1 0.0 2.1 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KEY63854.1 - 0.53 10.2 4.1 1.5 8.8 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 KEY63855.1 - 3e-17 63.4 0.0 3.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KEY63855.1 - 0.1 12.6 0.0 6 6.8 0.0 2.2 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain p450 PF00067.22 KEY63856.1 - 5.1e-38 131.0 0.0 1.2e-30 106.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 BDV_M PF16520.5 KEY63856.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 ssRNA-binding matrix protein of Bornaviridae Zn_clus PF00172.18 KEY63857.1 - 0.06 13.5 7.6 0.11 12.6 7.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY63857.1 - 0.089 11.8 1.4 0.17 10.9 1.4 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SnoaL_4 PF13577.6 KEY63858.1 - 2.1e-15 57.0 0.0 2.4e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Pectate_lyase_3 PF12708.7 KEY63859.1 - 9.6e-76 254.4 4.5 1.5e-68 230.8 2.0 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein Aspzincin_M35 PF14521.6 KEY63861.1 - 0.0011 19.5 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KEY63861.1 - 0.061 12.9 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Acetyltransf_17 PF17668.1 KEY63862.1 - 0.016 16.0 0.8 0.038 14.8 0.8 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.19 KEY63863.1 - 1.2e-22 80.7 1.6 4.7e-17 62.3 0.6 3.0 1 1 1 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KEY63863.1 - 4.7e-06 26.1 4.6 0.0074 15.6 0.1 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KEY63863.1 - 1.7e-05 24.2 0.0 4.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY63863.1 - 6.4e-05 22.2 1.0 0.00091 18.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY63863.1 - 0.021 15.1 0.0 0.087 13.1 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N_2 PF16884.5 KEY63865.1 - 1.9e-22 79.2 0.0 3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY63865.1 - 1.8e-18 66.8 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY63865.1 - 3.8e-08 34.5 0.0 6.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KEY63866.1 - 7.2e-60 202.4 0.1 8.1e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY63866.1 - 5e-45 153.4 0.0 6.6e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY63866.1 - 9e-10 38.8 0.2 1.3e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY63866.1 - 3.5e-05 23.4 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NosL PF05573.12 KEY63866.1 - 0.054 13.8 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 NosL HHH_5 PF14520.6 KEY63866.1 - 0.092 13.4 0.3 0.23 12.1 0.3 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain ABC_membrane PF00664.23 KEY63867.1 - 2.5e-76 256.9 36.2 2.7e-44 151.9 16.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY63867.1 - 4.6e-60 202.1 0.1 5.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY63867.1 - 8.5e-13 48.2 0.0 1.3e-06 28.0 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KEY63867.1 - 6.6e-07 28.5 0.0 0.0085 14.9 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KEY63867.1 - 1e-05 26.0 2.4 0.0018 18.7 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEY63867.1 - 1.9e-05 24.3 1.4 0.08 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEY63867.1 - 4.7e-05 22.8 0.8 1.2 8.3 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 KEY63867.1 - 7.1e-05 22.8 0.1 0.06 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEY63867.1 - 8.3e-05 22.9 0.1 0.77 10.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KEY63867.1 - 0.0015 18.3 0.8 0.45 10.2 0.1 3.4 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KEY63867.1 - 0.0047 17.1 1.7 9.8 6.5 0.1 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEY63867.1 - 0.02 15.3 2.1 8.6 6.8 0.0 4.2 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KEY63867.1 - 0.021 14.5 0.5 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KEY63867.1 - 0.062 13.1 3.6 16 5.2 0.0 3.7 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KEY63867.1 - 0.064 13.4 0.1 2 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KEY63867.1 - 0.079 12.1 0.0 7.9 5.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 KEY63867.1 - 0.084 12.9 0.8 15 5.5 0.0 3.6 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KEY63867.1 - 0.11 12.7 0.4 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEY63867.1 - 0.13 11.9 0.1 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEY63867.1 - 0.14 12.3 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KEY63867.1 - 0.15 12.6 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KEY63868.1 - 1.1e-11 44.3 0.3 2.6e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S8_N PF16361.5 KEY63869.1 - 0.06 13.8 0.0 0.076 13.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal of Subtilase family Gti1_Pac2 PF09729.9 KEY63871.1 - 4.7e-36 124.6 0.1 9.8e-30 104.0 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Pkinase PF00069.25 KEY63873.1 - 3.2e-08 33.3 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEY63873.1 - 3.6e-05 23.8 0.1 6.9e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY63873.1 - 0.0031 16.4 0.1 0.0067 15.3 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEY63873.1 - 0.0036 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KEY63873.1 - 0.0049 16.2 0.1 0.023 14.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KEY63873.1 - 0.095 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase KR PF08659.10 KEY63875.1 - 1.5e-39 135.8 4.0 1.7e-37 129.0 4.0 2.7 1 1 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KEY63875.1 - 1.3e-19 70.9 0.0 3.7e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 Acyl transferase domain ADH_zinc_N PF00107.26 KEY63875.1 - 1.3e-13 51.0 1.4 4.7e-13 49.3 0.0 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY63875.1 - 1.4e-12 48.8 0.0 8.6e-12 46.3 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEY63875.1 - 1.5e-08 34.9 0.0 3.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KEY63875.1 - 1.7e-07 30.9 3.4 4.7e-06 26.2 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 KEY63875.1 - 0.00037 20.3 0.1 0.00079 19.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain baeRF_family2 PF18844.1 KEY63875.1 - 0.18 11.9 0.5 0.54 10.3 0.5 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 IU_nuc_hydro PF01156.19 KEY63876.1 - 2.2e-08 34.0 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transferase PF02458.15 KEY63877.1 - 2.9e-11 42.7 0.1 4e-09 35.6 0.0 2.6 2 1 0 2 2 2 2 Transferase family SGL PF08450.12 KEY63878.1 - 5e-66 222.8 0.0 7.1e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KEY63878.1 - 2.1e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Arylesterase PD40 PF07676.12 KEY63878.1 - 0.11 12.4 0.2 0.78 9.8 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Phytase-like PF13449.6 KEY63878.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 Esterase-like activity of phytase NAD_binding_10 PF13460.6 KEY63880.1 - 7.7e-08 32.4 0.2 1.6e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY63880.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEY63880.1 - 6.2e-06 25.9 0.0 5.1e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KEY63880.1 - 0.00029 20.1 0.0 0.067 12.3 0.0 2.6 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KEY63880.1 - 0.0004 19.5 0.0 0.00074 18.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.8 KEY63880.1 - 0.007 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GDP_Man_Dehyd PF16363.5 KEY63880.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEY63880.1 - 0.041 13.0 0.0 0.094 11.8 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KEY63880.1 - 0.073 13.0 0.1 41 4.0 0.1 3.3 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.15 KEY63880.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Lactamase_B PF00753.27 KEY63882.1 - 1.7e-17 64.1 4.0 1.4e-15 57.8 4.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY63882.1 - 2.6e-06 27.1 2.9 1.7e-05 24.4 2.7 2.3 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEY63882.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KEY63882.1 - 0.026 14.5 0.0 0.063 13.3 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase associated winged helix domain Lactamase_B_6 PF16661.5 KEY63882.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain ketoacyl-synt PF00109.26 KEY63883.1 - 2.7e-72 243.4 0.0 6.4e-72 242.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY63883.1 - 5.6e-46 157.5 0.0 1.7e-45 156.0 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KEY63883.1 - 8.3e-46 156.7 0.0 2.5e-44 151.8 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 KEY63883.1 - 5.1e-34 116.8 0.2 1.6e-33 115.2 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY63883.1 - 8.5e-09 35.9 0.0 1.6e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY63883.1 - 6.8e-08 32.8 0.4 2.2e-07 31.1 0.4 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEY63883.1 - 0.00044 19.7 0.1 0.00091 18.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Myb_DNA-binding PF00249.31 KEY63884.1 - 0.0026 17.9 0.1 0.0058 16.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY63884.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.24 KEY63885.1 - 0.00013 21.8 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Imm31 PF15591.6 KEY63885.1 - 0.03 14.2 0.2 0.058 13.2 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 31 DUF2841 PF11001.8 KEY63886.1 - 5e-36 123.5 3.7 1e-35 122.5 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Tyrosinase PF00264.20 KEY63887.1 - 1.3e-50 172.8 0.1 1.7e-50 172.3 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_2 PF13347.6 KEY63888.1 - 1.1e-09 37.3 12.1 1.3e-09 37.1 8.4 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 KEY63888.1 - 3.1e-05 23.2 3.4 8e-05 21.8 3.4 1.7 1 0 0 1 1 1 1 PUCC protein SR-25 PF10500.9 KEY63889.1 - 0.13 11.9 10.2 0.22 11.1 10.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MAP70 PF07058.11 KEY63889.1 - 0.13 11.0 4.1 0.15 10.8 4.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 TAF1D PF15333.6 KEY63889.1 - 0.19 11.5 2.7 0.26 11.0 2.7 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D CCDC106 PF15794.5 KEY63889.1 - 4.9 6.8 7.1 6.5 6.4 7.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM199X PF15814.5 KEY63889.1 - 7.3 5.5 11.3 1.3 8.0 8.1 1.4 2 0 0 2 2 2 0 Protein family FAM199X Myb_DNA-bind_6 PF13921.6 KEY63890.1 - 5.6e-09 36.1 0.0 0.0017 18.5 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEY63890.1 - 2.6e-08 33.9 0.2 0.0038 17.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HET PF06985.11 KEY63891.1 - 7.9e-25 87.9 0.0 2.1e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_2c PF01411.19 KEY63891.1 - 0.1 11.1 0.0 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class II (A) Pkinase_fungal PF17667.1 KEY63893.1 - 4.7e-05 22.3 0.0 6.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase HSDR_N_2 PF13588.6 KEY63893.1 - 0.055 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Las1 PF04031.13 KEY63895.1 - 2.2e-62 209.7 4.6 3.8e-62 208.9 4.6 1.4 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KEY63896.1 - 5.6e-23 81.3 0.8 1.1e-22 80.4 0.8 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KEY63896.1 - 4.9e-06 26.7 0.1 9.7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_7 PF13499.6 KEY63896.1 - 0.0015 18.9 0.0 0.047 14.1 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KEY63896.1 - 0.042 13.8 0.0 77 3.6 0.0 4.6 5 1 0 5 5 5 0 EF-hand domain BcrAD_BadFG PF01869.20 KEY63896.1 - 0.047 13.2 0.1 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family EF-hand_1 PF00036.32 KEY63896.1 - 0.15 11.7 1.1 2.5 7.8 0.0 3.4 4 0 0 4 4 4 0 EF hand bZIP_1 PF00170.21 KEY63899.1 - 0.0046 17.0 13.3 0.0093 16.0 13.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor EF-G-binding_N PF07299.11 KEY63899.1 - 0.055 14.0 1.2 0.092 13.3 1.2 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Golgin_A5 PF09787.9 KEY63899.1 - 0.19 11.2 7.1 0.26 10.7 7.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1053 PF06327.14 KEY63899.1 - 0.19 12.3 2.1 0.35 11.5 2.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DivIC PF04977.15 KEY63899.1 - 0.55 10.0 8.1 1.2 9.0 3.7 2.3 1 1 1 2 2 2 0 Septum formation initiator TrbI_Ftype PF09677.10 KEY63899.1 - 0.89 9.9 2.6 0.52 10.6 0.5 1.6 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) bZIP_2 PF07716.15 KEY63899.1 - 1.1 9.4 16.0 2.2 8.4 7.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper WD40_alt PF14077.6 KEY63899.1 - 1.8 8.5 6.1 0.37 10.7 0.8 2.1 1 1 1 2 2 2 0 Alternative WD40 repeat motif LCD1 PF09798.9 KEY63899.1 - 7.3 5.0 6.1 9.3 4.6 6.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FAD_binding_4 PF01565.23 KEY63900.1 - 7.5e-18 64.6 0.9 1.7e-17 63.4 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY63900.1 - 9.6e-10 38.4 0.1 2.5e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like RT_RNaseH PF17917.1 KEY63902.1 - 4.6e-12 46.1 0.0 8.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KEY63902.1 - 9.6e-11 41.6 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 KEY63902.1 - 3e-08 33.4 0.0 6.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_61 PF03443.14 KEY63903.1 - 0.0035 17.3 0.0 0.0072 16.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Mo-co_dimer PF03404.16 KEY63903.1 - 0.0082 16.2 0.2 0.013 15.5 0.2 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Phage_holin_3_6 PF07332.11 KEY63904.1 - 1.7 8.7 8.6 0.091 12.8 0.5 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Metallophos PF00149.28 KEY63905.1 - 2.3e-11 44.6 0.0 4e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY63905.1 - 7.5e-07 29.5 0.1 6.2e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 KEY63905.1 - 0.088 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 MutL protein Fungal_trans PF04082.18 KEY63907.1 - 2.1e-14 53.2 0.2 4e-14 52.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY63907.1 - 2.9e-05 24.1 16.9 5.2e-05 23.3 16.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KEY63907.1 - 0.32 10.9 15.5 0.47 10.4 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gastrin PF00918.17 KEY63907.1 - 9.9 7.2 7.1 14 6.7 4.8 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family NAD_binding_10 PF13460.6 KEY63908.1 - 2.9e-25 89.2 0.0 3.3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY63908.1 - 0.00055 19.6 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEY63908.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MIP PF00230.20 KEY63909.1 - 4.3e-40 137.8 12.6 5e-40 137.6 12.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADH_N PF08240.12 KEY63910.1 - 4.1e-29 100.7 0.6 7.9e-29 99.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY63910.1 - 3.1e-10 40.1 0.2 3.1e-08 33.7 0.2 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEY63910.1 - 2e-06 27.6 1.7 2e-06 27.6 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated NADH_4Fe-4S PF10589.9 KEY63910.1 - 0.01 15.9 1.3 0.042 13.9 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Aminotran_3 PF00202.21 KEY63910.1 - 0.013 14.2 0.6 0.18 10.4 0.3 2.0 2 0 0 2 2 2 0 Aminotransferase class-III Met_10 PF02475.16 KEY63910.1 - 0.042 13.6 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein 2-Hacid_dh_C PF02826.19 KEY63910.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEY63910.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KEY63910.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FANCL_C PF11793.8 KEY63910.1 - 0.064 13.4 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain CTP_transf_like PF01467.26 KEY63911.1 - 8.5e-24 84.4 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2461 PF09365.10 KEY63913.1 - 2e-63 214.2 0.1 2.5e-63 213.8 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) HMG14_17 PF01101.18 KEY63913.1 - 0.09 13.7 8.3 0.18 12.8 6.5 2.4 2 0 0 2 2 2 0 HMG14 and HMG17 Cwf_Cwc_15 PF04889.12 KEY63913.1 - 0.36 10.5 7.9 0.56 9.9 7.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KEY63913.1 - 0.89 7.6 4.8 1.1 7.2 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 KEY63913.1 - 0.97 9.2 5.6 1.6 8.5 5.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KEY63913.1 - 8.6 5.6 7.4 12 5.1 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Fungal_trans PF04082.18 KEY63914.1 - 1.6e-13 50.3 4.5 2e-13 50.0 1.5 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 KEY63915.1 - 4.8e-39 134.4 0.0 6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KEY63916.1 - 2.9e-43 147.6 0.0 4.4e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY63916.1 - 5.3e-28 97.6 0.6 3e-27 95.2 0.5 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY63916.1 - 0.00051 20.1 0.0 0.00085 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KEY63916.1 - 0.04 13.2 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit adh_short_C2 PF13561.6 KEY63917.1 - 8e-60 202.3 0.0 1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY63917.1 - 4.1e-47 160.2 0.1 5.3e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY63917.1 - 1.7e-09 37.8 0.0 2.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY63917.1 - 0.007 15.8 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KEY63917.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IL2RB_N1 PF18707.1 KEY63918.1 - 0.12 12.9 0.5 0.27 11.8 0.5 1.5 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 Aldo_ket_red PF00248.21 KEY63919.1 - 0.0044 16.3 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.8 KEY63920.1 - 5.7e-20 71.5 0.1 1.1e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3435 PF11917.8 KEY63921.1 - 5.4e-49 167.2 1.0 8.2e-44 150.2 1.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3435) Ada3 PF10198.9 KEY63921.1 - 0.053 13.7 1.4 0.14 12.3 1.4 1.7 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Phage_integrase PF00589.22 KEY63921.1 - 0.089 12.6 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Phage integrase family DUF3073 PF11273.8 KEY63921.1 - 2.4 8.9 12.7 12 6.8 6.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3073) Abhydrolase_6 PF12697.7 KEY63922.1 - 1.6e-13 51.7 8.2 2.2e-13 51.3 8.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY63922.1 - 5.8e-13 49.1 0.6 1.1e-12 48.1 0.6 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 KEY63922.1 - 3.5e-07 29.2 0.0 4.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KEY63922.1 - 2.7e-05 23.5 0.3 7.1e-05 22.2 0.2 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KEY63922.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 KEY63923.1 - 3.2e-13 49.8 0.0 4.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY63923.1 - 1.7e-11 44.6 0.0 3.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY63923.1 - 3e-10 40.7 0.0 6.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY63923.1 - 6.5e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY63923.1 - 2.1e-07 30.9 0.0 8.4e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEY63923.1 - 0.00054 19.5 0.0 0.0012 18.4 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEY63923.1 - 0.0038 16.8 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEY63923.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KEY63923.1 - 0.017 14.5 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KEY63923.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Gln-synt_C PF00120.24 KEY63924.1 - 1.6e-83 280.6 0.0 2.1e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KEY63924.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain GST_N PF02798.20 KEY63924.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraI_2B PF18340.1 KEY63925.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain adh_short PF00106.25 KEY63926.1 - 5.2e-19 68.5 0.0 1.6e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY63926.1 - 2.2e-12 47.1 0.1 2.9e-11 43.4 0.0 2.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY63926.1 - 7.6e-07 29.2 0.2 1.3e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY63926.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEY63926.1 - 0.058 13.6 0.7 1 9.6 0.2 2.4 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KEY63926.1 - 0.076 12.4 1.4 0.69 9.2 0.1 2.1 1 1 1 2 2 2 0 ThiF family GXWXG PF14231.6 KEY63927.1 - 0.083 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein Ecl1 PF12855.7 KEY63928.1 - 3.9e-36 125.8 18.6 3.9e-36 125.8 18.6 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KEY63928.1 - 0.14 12.2 2.0 0.3 11.2 2.0 1.5 1 0 0 1 1 1 0 MYND finger Pec_lyase_C PF00544.19 KEY63929.1 - 9.7e-20 71.1 0.8 1.4e-19 70.5 0.8 1.2 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 KEY63929.1 - 2.6e-10 40.1 12.7 2.6e-10 40.1 12.7 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.6 KEY63929.1 - 4.4e-06 26.6 9.6 1.3e-05 25.1 9.6 1.7 1 1 0 1 1 1 1 Right handed beta helix region Toxin_7 PF05980.12 KEY63929.1 - 0.15 12.3 2.7 0.32 11.3 2.7 1.6 1 0 0 1 1 1 0 Toxin 7 4HBT_3 PF13622.6 KEY63931.1 - 3.5e-35 122.4 0.0 4.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KEY63931.1 - 0.11 12.8 0.1 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Thioesterase superfamily Dimer_Tnp_hAT PF05699.14 KEY63934.1 - 3.2e-07 30.0 0.4 9.8e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region BLF1 PF17752.1 KEY63934.1 - 0.035 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Burkholderia lethal factor 1 HET PF06985.11 KEY63935.1 - 8.4e-26 91.1 0.0 1.9e-25 90.0 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Allene_ox_cyc PF06351.11 KEY63935.1 - 0.23 11.2 0.0 0.47 10.2 0.0 1.5 1 0 0 1 1 1 0 Allene oxide cyclase FAD_binding_4 PF01565.23 KEY63936.1 - 4.8e-18 65.2 5.6 1.6e-17 63.6 5.6 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY63936.1 - 2.6e-07 30.6 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PAP2 PF01569.21 KEY63937.1 - 7.8e-22 77.5 2.9 7.8e-22 77.5 2.9 2.5 2 1 0 2 2 2 1 PAP2 superfamily PalH PF08733.10 KEY63937.1 - 0.083 11.9 2.2 0.13 11.2 2.2 1.2 1 0 0 1 1 1 0 PalH/RIM21 APH PF01636.23 KEY63939.1 - 4.4e-15 56.3 0.0 1.5e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY63939.1 - 1.7e-05 24.5 0.0 5.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KEY63939.1 - 0.066 12.6 0.0 9.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Peptidase_M28 PF04389.17 KEY63941.1 - 6.5e-39 133.7 0.0 1.2e-38 132.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY63941.1 - 4.3e-07 29.8 0.2 1.2e-06 28.4 0.2 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 LCM PF04072.14 KEY63942.1 - 3e-13 50.1 0.0 3.2e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Tymo_coat PF00983.18 KEY63943.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Tymovirus coat protein KR PF08659.10 KEY63945.1 - 2.6e-24 86.1 0.0 4.9e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KEY63945.1 - 3.9e-08 33.5 0.0 9.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pkinase PF00069.25 KEY63949.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEY63949.1 - 0.00069 19.6 0.1 0.0024 17.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY63949.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KEY63949.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DDE_Tnp_1_7 PF13843.6 KEY63951.1 - 0.00024 20.6 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Suf PF05843.14 KEY63951.1 - 0.025 14.6 0.3 0.029 14.4 0.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MitoNEET_N PF10660.9 KEY63952.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus NmrA PF05368.13 KEY63954.1 - 1.1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY63954.1 - 1.4e-12 47.9 0.0 3.3e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEY63954.1 - 5.6e-06 26.0 0.1 0.0019 17.7 0.0 3.1 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY63954.1 - 0.038 13.4 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEY63954.1 - 0.08 12.0 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain PAF-AH_p_II PF03403.13 KEY63956.1 - 9.7e-44 149.4 0.0 2.5e-42 144.7 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KEY63956.1 - 0.00022 20.2 0.0 0.0011 18.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KEY63956.1 - 0.018 14.0 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 KEY63956.1 - 0.057 12.7 0.0 8.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 KEY63957.1 - 3.2e-08 33.3 0.2 5e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY63957.1 - 4e-08 33.9 0.0 6.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase zf-RING_UBOX PF13445.6 KEY63958.1 - 0.0015 18.5 4.6 0.0015 18.5 4.6 3.3 2 2 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEY63958.1 - 0.0094 15.8 6.9 0.0094 15.8 6.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY63958.1 - 0.015 15.6 5.2 0.015 15.6 5.2 2.8 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KEY63958.1 - 0.055 13.3 4.0 0.055 13.3 4.0 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY63958.1 - 4.9 7.1 16.1 0.51 10.2 6.8 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 SDA1 PF05285.12 KEY63959.1 - 0.0013 18.2 0.9 0.0017 17.8 0.9 1.2 1 0 0 1 1 1 1 SDA1 CD99L2 PF12301.8 KEY63959.1 - 0.004 17.5 3.0 0.008 16.5 3.0 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 CDC45 PF02724.14 KEY63959.1 - 0.02 13.2 1.7 0.024 12.9 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KEY63959.1 - 0.028 13.8 1.8 0.026 13.9 1.8 1.2 1 0 0 1 1 1 0 BUD22 DUF4690 PF15756.5 KEY63959.1 - 0.05 14.2 0.0 0.25 12.0 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Amnionless PF14828.6 KEY63959.1 - 0.056 12.3 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless eIF-3c_N PF05470.12 KEY63959.1 - 0.063 11.6 0.9 0.075 11.3 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Podoplanin PF05808.11 KEY63959.1 - 0.073 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin NOA36 PF06524.12 KEY63959.1 - 0.18 11.1 11.2 0.31 10.3 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KEY63959.1 - 0.52 10.2 7.1 0.82 9.5 7.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PMP1_2 PF08114.11 KEY63959.1 - 0.78 9.5 2.4 1.8 8.4 2.4 1.6 1 0 0 1 1 1 0 ATPase proteolipid family DNA_pol_phi PF04931.13 KEY63959.1 - 0.92 7.5 16.2 1.6 6.7 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KEY63959.1 - 0.97 9.1 6.2 3.5 7.3 5.9 1.9 2 0 0 2 2 2 0 FAM176 family VSP PF03302.13 KEY63959.1 - 1.3 7.8 3.5 2.2 7.0 3.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein RXT2_N PF08595.11 KEY63959.1 - 2.3 8.2 6.8 4.2 7.4 6.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 KEY63959.1 - 4.9 6.2 8.8 6.7 5.8 8.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 KEY63959.1 - 7.1 5.6 8.4 10 5.1 8.4 1.1 1 0 0 1 1 1 0 Pes-10 Voldacs PF03517.13 KEY63962.1 - 6.4e-22 78.2 0.1 1.9e-21 76.6 0.1 1.8 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Myc_N PF01056.18 KEY63963.1 - 0.3 10.9 17.3 0.13 12.1 14.0 2.0 2 0 0 2 2 2 0 Myc amino-terminal region CAF1A PF12253.8 KEY63963.1 - 0.37 11.0 7.7 3.1 8.0 7.1 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF4611 PF15387.6 KEY63963.1 - 0.39 10.9 7.1 1.5 9.1 7.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2052 PF09747.9 KEY63963.1 - 0.63 10.1 14.3 2.3 8.3 14.3 1.9 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1996 PF09362.10 KEY63964.1 - 5.2e-80 268.8 0.2 6.7e-80 268.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Rib_recp_KP_reg PF05104.12 KEY63964.1 - 4.7 8.2 10.7 9.2 7.3 10.7 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region UBA PF00627.31 KEY63965.1 - 1.5e-07 31.1 0.1 3.3e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 KEY63965.1 - 0.0012 18.8 0.0 19 5.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY63965.1 - 0.0017 18.1 0.0 2.5 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY63965.1 - 0.0023 18.2 0.1 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 KEY63965.1 - 0.047 13.8 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 DnaJ domain DUF630 PF04783.12 KEY63965.1 - 0.13 12.4 0.2 0.45 10.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF630) UQ_con PF00179.26 KEY63966.1 - 6.5e-44 149.0 0.0 1.2e-23 83.3 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Formyl_trans_N PF00551.19 KEY63967.1 - 2.8e-33 115.2 0.0 3.3e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase tRNA-synt_1e PF01406.19 KEY63968.1 - 9.1e-113 376.6 0.0 1.6e-112 375.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KEY63968.1 - 1.1e-05 24.4 0.1 0.11 11.2 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KEY63968.1 - 0.22 10.4 2.0 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain GCD14 PF08704.10 KEY63969.1 - 8.5e-65 218.9 1.9 5.8e-63 212.8 0.1 3.3 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit LSM PF01423.22 KEY63970.1 - 1.9e-16 59.5 0.2 2.8e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF1993 PF09351.10 KEY63972.1 - 0.35 11.0 7.8 2.3 8.3 0.7 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF1993) EMP24_GP25L PF01105.24 KEY63972.1 - 0.75 9.7 4.5 1.9 8.4 0.6 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD p450 PF00067.22 KEY63973.1 - 2.6e-75 253.9 0.0 3.3e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.28 KEY63974.1 - 1.5e-17 64.3 0.0 4.1e-17 62.9 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 HET PF06985.11 KEY63975.1 - 4.4e-05 23.9 0.0 7.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2706 PF10913.8 KEY63976.1 - 0.19 11.6 0.3 0.85 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) FLILHELTA PF10306.9 KEY63977.1 - 4.9e-33 113.4 0.0 8.9e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KEY63977.1 - 0.002 18.6 0.5 0.0026 18.2 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.19 KEY63978.1 - 1.2e-53 180.8 0.0 1.4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 KEY63979.1 - 1.3e-136 456.3 2.9 2e-136 455.7 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KEY63979.1 - 9.7e-26 89.9 0.3 3.3e-25 88.2 0.3 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KEY63979.1 - 3.6e-06 27.2 0.0 1.4e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MS_channel PF00924.18 KEY63980.1 - 1.8e-20 73.3 1.2 3.1e-20 72.6 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KEY63980.1 - 0.00039 19.8 0.3 0.00097 18.5 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEY63980.1 - 0.0094 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KEY63980.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KEY63980.1 - 0.039 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KEY63980.1 - 0.04 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.8 KEY63980.1 - 0.16 12.1 0.7 0.44 10.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function BRCT PF00533.26 KEY63981.1 - 1.8e-06 28.2 0.0 5.7e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEY63981.1 - 2.4e-06 27.9 0.0 5.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KEY63981.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KEY63981.1 - 0.12 12.5 0.0 18 5.4 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ETF_QO PF05187.13 KEY63982.1 - 7.5e-25 87.1 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KEY63982.1 - 2.8e-08 33.8 1.4 0.00015 21.5 0.7 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY63982.1 - 1.3e-07 31.7 0.0 3.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY63982.1 - 8.2e-05 22.0 0.0 0.00025 20.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY63982.1 - 0.00012 21.3 2.7 0.0058 15.8 1.4 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEY63982.1 - 0.00068 20.2 0.0 1.3 9.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY63982.1 - 0.00076 18.8 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEY63982.1 - 0.00089 18.6 0.1 0.0027 17.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEY63982.1 - 0.00091 18.0 0.4 0.0013 17.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KEY63982.1 - 0.0011 19.0 0.1 0.0058 16.6 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEY63982.1 - 0.0047 16.2 0.2 0.0068 15.7 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEY63982.1 - 0.0084 15.0 0.1 0.21 10.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KEY63982.1 - 0.011 15.1 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEY63982.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KEY63982.1 - 0.079 12.0 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KEY63982.1 - 0.16 11.0 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.21 KEY63983.1 - 1.4e-67 223.6 0.1 6.9e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KEY63983.1 - 0.0001 22.4 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KEY63983.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 KEY63984.1 - 2.3e-37 129.4 1.1 2.7e-37 129.2 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEY63984.1 - 5.5e-05 22.4 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEY63984.1 - 0.0006 19.8 0.7 0.47 10.4 0.0 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY63984.1 - 0.00087 19.5 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Surp PF01805.20 KEY63985.1 - 5.1e-09 36.0 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Surp module Copper-fist PF00649.18 KEY63986.1 - 3.2e-18 64.9 0.4 7.1e-18 63.8 0.4 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Bactofilin PF04519.13 KEY63986.1 - 2.5 8.5 6.8 1.1 9.6 1.2 3.0 3 1 1 4 4 4 0 Polymer-forming cytoskeletal Methyltransf_16 PF10294.9 KEY63987.1 - 1.6e-12 47.5 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PhyH PF05721.13 KEY63988.1 - 3.9e-12 46.9 0.0 6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 KEY63989.1 - 4.2e-13 48.9 0.3 1.6e-12 47.0 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY63989.1 - 6.6e-08 32.6 10.9 0.0017 18.7 0.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY63989.1 - 5.1e-05 23.8 10.5 0.011 16.5 2.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY63989.1 - 9e-05 22.7 16.0 0.00015 22.1 3.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KEY63989.1 - 0.027 14.8 1.0 0.74 10.2 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KEY63989.1 - 0.98 9.4 5.9 4.6 7.2 2.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Nop14 PF04147.12 KEY63990.1 - 1.9 6.6 15.0 2.3 6.3 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pol_alpha_B_N PF08418.10 KEY63991.1 - 1.2e-77 261.3 0.0 1.5e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KEY63991.1 - 2.4e-41 141.4 0.1 3.3e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFAP1 PF06991.11 KEY63992.1 - 1.4e-63 214.6 27.6 1.4e-63 214.6 27.6 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing GP67 PF17634.2 KEY63992.1 - 0.00029 21.2 12.5 0.00029 21.2 12.5 4.7 5 0 0 5 5 5 1 Gene product 67 DNA_pol_phi PF04931.13 KEY63992.1 - 0.11 10.5 32.1 0.24 9.5 32.1 1.5 1 0 0 1 1 1 0 DNA polymerase phi RmlD_sub_bind PF04321.17 KEY63993.1 - 6.4e-51 173.1 0.0 7.9e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KEY63993.1 - 3.7e-19 69.1 0.0 4.9e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY63993.1 - 2e-08 33.7 0.2 7.2e-07 28.6 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEY63993.1 - 4.5e-08 32.9 0.0 8.7e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY63993.1 - 1.7e-07 30.7 0.0 0.00094 18.4 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEY63993.1 - 1.5e-06 27.4 0.0 5.3e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PH PF00169.29 KEY63994.1 - 0.00033 21.1 0.0 0.00079 19.9 0.0 1.6 1 0 0 1 1 1 1 PH domain polyprenyl_synt PF00348.17 KEY63995.1 - 1.4e-90 302.9 0.0 2.1e-90 302.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase YkyB PF14177.6 KEY63995.1 - 0.054 13.8 0.1 0.37 11.1 0.1 2.2 1 1 1 2 2 2 0 YkyB-like protein ANAPC8 PF04049.13 KEY63996.1 - 1e-55 187.6 0.7 2.9e-55 186.2 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KEY63996.1 - 2.4e-22 77.2 12.8 6.8e-05 22.8 0.0 7.7 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KEY63996.1 - 1.9e-21 74.9 6.6 8.6e-05 22.2 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY63996.1 - 9.1e-15 53.5 15.9 0.029 14.5 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY63996.1 - 5.3e-11 42.4 12.1 0.0056 17.4 0.1 8.4 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEY63996.1 - 2e-08 33.8 0.2 1.1e-06 28.2 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 KEY63996.1 - 1.6e-07 31.8 4.9 6 7.5 0.0 7.1 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY63996.1 - 4.8e-07 30.3 7.5 1.4e-05 25.7 0.4 5.6 6 1 2 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY63996.1 - 5.7e-07 29.7 8.6 0.045 14.0 0.3 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEY63996.1 - 2.7e-06 27.0 9.4 0.044 13.8 0.0 5.8 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY63996.1 - 0.00011 22.4 25.0 0.25 11.6 0.1 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY63996.1 - 0.00028 21.1 0.2 6 7.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KEY63996.1 - 0.00042 20.4 2.7 0.014 15.5 0.2 3.1 2 1 1 3 3 2 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 KEY63996.1 - 0.00044 20.3 9.2 2.2 8.5 0.3 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY63996.1 - 0.0013 18.1 0.6 0.0092 15.4 0.1 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 KEY63996.1 - 0.0085 15.9 5.9 2.2 8.3 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY63996.1 - 0.05 14.3 22.6 0.72 10.6 0.2 8.7 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 KEY63996.1 - 0.067 12.4 3.9 0.18 11.0 1.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KEY63996.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Far-17a_AIG1 PF04750.14 KEY63997.1 - 0.047 13.0 0.8 0.047 13.0 0.0 1.4 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Vps54 PF07928.12 KEY63998.1 - 6e-52 175.6 3.7 6.1e-51 172.4 0.1 3.3 3 0 0 3 3 3 1 Vps54-like protein DUF2451 PF10474.9 KEY63998.1 - 7.1e-06 26.0 0.0 0.00013 21.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KEY63998.1 - 1.6e-05 24.3 1.2 1.6e-05 24.3 1.2 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex OmpH PF03938.14 KEY63998.1 - 0.17 12.3 5.8 2.5 8.4 0.3 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Kre28 PF17097.5 KEY63998.1 - 1.9 7.3 6.6 0.97 8.3 0.0 2.7 2 1 1 3 3 3 0 Spindle pole body component Cytochrom_B562 PF07361.11 KEY63998.1 - 3.4 8.4 7.0 8.8 7.1 0.4 4.0 4 0 0 4 4 4 0 Cytochrome b562 ZapB PF06005.12 KEY63998.1 - 4.1 7.9 13.4 2.1 8.8 2.6 3.1 2 0 0 2 2 2 0 Cell division protein ZapB COG2 PF06148.11 KEY63998.1 - 5.7 7.0 8.2 2.7 8.1 1.8 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.23 KEY63999.1 - 5.5e-106 352.7 0.2 4.7e-105 349.6 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEY63999.1 - 1.8e-36 124.8 0.6 3.4e-36 123.9 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEY63999.1 - 4.3e-28 97.6 1.3 1.1e-27 96.3 1.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY63999.1 - 1.1e-15 58.1 0.5 3.2e-15 56.6 0.5 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEY63999.1 - 7.5e-07 28.7 0.0 0.0002 20.8 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEY63999.1 - 2.5e-05 24.3 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEY63999.1 - 0.00017 21.4 0.0 0.00074 19.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEY63999.1 - 0.059 13.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KEY63999.1 - 0.072 13.5 0.2 0.32 11.4 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PAS_9 PF13426.7 KEY64000.1 - 5.4e-16 58.7 0.0 8.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KEY64000.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KEY64000.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KEY64000.1 - 0.0099 16.2 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KEY64000.1 - 0.095 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold Fapy_DNA_glyco PF01149.24 KEY64001.1 - 1.3e-36 125.7 0.1 3.1e-36 124.5 0.1 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KEY64001.1 - 4.3e-22 77.9 0.0 8e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KEY64001.1 - 0.00091 18.1 0.0 0.0027 16.6 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NUC153 PF08159.12 KEY64002.1 - 9.7e-12 44.5 0.5 1.7e-11 43.7 0.5 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KEY64002.1 - 4.6e-06 27.3 0.0 0.07 14.0 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64002.1 - 0.092 13.1 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3568 PF12092.8 KEY64002.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Hist_rich_Ca-bd PF10529.9 KEY64002.1 - 1.7 9.0 8.6 6.9 7.0 8.6 2.1 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region CD99L2 PF12301.8 KEY64003.1 - 0.0034 17.7 0.9 0.0047 17.2 0.6 1.4 1 1 0 1 1 1 1 CD99 antigen like protein 2 SNN_transmemb PF09049.10 KEY64003.1 - 0.36 10.8 8.8 0.65 10.0 8.8 1.3 1 0 0 1 1 1 0 Stannin transmembrane HALZ PF02183.18 KEY64004.1 - 0.0013 18.9 0.8 0.0078 16.4 0.0 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Ribosomal_L33 PF00471.20 KEY64005.1 - 8.4e-05 22.9 0.0 9.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.21 KEY64006.1 - 1.1e-37 130.1 0.0 1.7e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4350 PF14258.6 KEY64006.1 - 0.0021 18.5 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) Cys_Met_Meta_PP PF01053.20 KEY64006.1 - 0.032 12.8 0.0 0.054 12.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SpoVAE PF14097.6 KEY64006.1 - 0.14 11.8 0.1 0.4 10.3 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AE1 RPN7 PF10602.9 KEY64007.1 - 4.7e-57 192.5 1.8 5.9e-57 192.2 0.4 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KEY64007.1 - 8.8e-15 55.1 0.0 2.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF5423 PF17461.2 KEY64008.1 - 0.066 12.1 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Pox_MCEL PF03291.16 KEY64009.1 - 7.2e-70 235.7 0.0 1.1e-48 166.1 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KEY64009.1 - 2.2e-10 41.1 0.0 5.1e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KEY64009.1 - 1.8e-09 38.3 0.0 0.0018 19.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEY64009.1 - 1.3e-07 31.5 0.0 4.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64009.1 - 1.8e-06 28.5 0.0 0.056 14.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KEY64009.1 - 4.3e-06 26.7 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KEY64009.1 - 0.00044 19.5 0.0 0.0007 18.9 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family FAM92 PF06730.11 KEY64009.1 - 0.34 10.3 1.7 0.54 9.6 1.7 1.2 1 0 0 1 1 1 0 FAM92 protein EF_assoc_2 PF08356.12 KEY64010.1 - 3.8e-35 119.8 0.0 8.3e-35 118.7 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KEY64010.1 - 7.9e-30 102.3 0.1 1.8e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KEY64010.1 - 1.1e-22 80.4 0.0 3.3e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEY64010.1 - 3.3e-14 53.1 0.0 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEY64010.1 - 4.2e-08 33.3 0.0 0.0018 18.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KEY64010.1 - 3.6e-07 29.3 6.1 0.0048 16.3 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KEY64010.1 - 1.5e-06 28.5 0.8 0.0015 18.9 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEY64010.1 - 2.1e-06 27.2 5.0 0.018 14.9 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.6 KEY64010.1 - 3e-06 27.5 0.0 0.075 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY64010.1 - 1.8e-05 25.2 0.1 0.033 14.6 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.23 KEY64010.1 - 2.8e-05 24.2 0.0 0.044 13.8 0.1 2.8 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KEY64010.1 - 8.1e-05 22.6 0.2 1.4 8.8 0.1 3.4 2 1 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KEY64010.1 - 0.00039 20.1 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KEY64010.1 - 0.00051 19.6 0.0 4.3 6.8 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KEY64010.1 - 0.0012 18.6 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEY64010.1 - 0.0015 19.1 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 KEY64010.1 - 0.0026 18.0 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Ploopntkinase3 PF18751.1 KEY64010.1 - 0.0033 17.4 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KEY64010.1 - 0.0037 17.6 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 KEY64010.1 - 0.0042 16.9 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KEY64010.1 - 0.0074 16.8 0.1 1.2 9.7 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KEY64010.1 - 0.0099 16.0 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KEY64010.1 - 0.013 14.8 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Septin NACHT PF05729.12 KEY64010.1 - 0.014 15.3 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain EF-hand_5 PF13202.6 KEY64010.1 - 0.02 14.4 9.6 0.13 11.8 2.3 2.7 2 0 0 2 2 2 0 EF hand AAA_7 PF12775.7 KEY64010.1 - 0.027 14.0 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KEY64010.1 - 0.034 13.3 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 KEY64010.1 - 0.049 13.5 1.8 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 EF hand AIG1 PF04548.16 KEY64010.1 - 0.054 12.8 0.0 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 KEY64010.1 - 0.069 12.7 0.1 16 5.1 0.0 3.8 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KEY64010.1 - 0.1 11.7 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain AAA PF00004.29 KEY64010.1 - 0.1 13.0 0.1 9.6 6.6 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KEY64010.1 - 0.16 11.2 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IIGP PF05049.13 KEY64010.1 - 0.18 10.8 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.32 KEY64011.1 - 4.6e-11 43.1 15.4 0.0025 18.6 0.3 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64011.1 - 1.7e-07 31.4 0.0 0.017 15.4 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY64011.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KEY64011.1 - 0.079 11.5 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain MFS_1 PF07690.16 KEY64013.1 - 7.6e-37 127.1 63.4 4.4e-32 111.4 52.2 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KEY64013.1 - 1.7e-05 23.8 4.1 0.0055 15.5 0.0 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter DUF1129 PF06570.11 KEY64013.1 - 0.19 11.2 1.1 0.56 9.7 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TIL PF01826.17 KEY64014.1 - 6.6e-14 51.9 17.5 8.3e-14 51.6 17.5 1.1 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 KEY64014.1 - 0.062 13.3 0.5 0.062 13.3 0.5 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like RGS PF00615.19 KEY64015.1 - 5.5e-08 33.1 0.0 1.9e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DJ-1_PfpI PF01965.24 KEY64016.1 - 4.4e-18 65.6 0.0 5.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Ank_2 PF12796.7 KEY64017.1 - 1.7e-15 57.4 0.0 7.3e-08 32.9 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEY64017.1 - 3.2e-14 52.6 0.9 0.3 11.6 0.0 8.2 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 KEY64017.1 - 5.6e-11 42.8 1.7 1.3 9.7 0.0 6.9 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY64017.1 - 4.5e-10 38.9 0.0 6.1 7.8 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KEY64017.1 - 0.00054 20.2 1.3 0.68 10.3 0.0 5.2 4 2 1 5 5 5 1 Ankyrin repeats (many copies) NACHT PF05729.12 KEY64017.1 - 0.0011 18.9 0.1 0.0025 17.7 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.6 KEY64017.1 - 0.37 11.2 1.6 0.53 10.7 0.5 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hyd_65N_2 PF14498.6 KEY64018.1 - 2.4e-51 174.9 0.0 3.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 KEY64018.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Acetyltransf_10 PF13673.7 KEY64019.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY64019.1 - 1e-08 35.5 0.0 2.1e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY64019.1 - 2.9e-08 33.9 0.0 3.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KEY64019.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ThrE PF06738.12 KEY64020.1 - 2.6e-66 223.5 22.7 8.5e-64 215.2 3.2 2.8 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KEY64020.1 - 1.1e-13 51.4 11.8 1.1e-13 51.4 11.8 2.7 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DLH PF01738.18 KEY64021.1 - 9.8e-28 97.2 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family SnoaL PF07366.12 KEY64022.1 - 8.5e-06 25.6 0.1 1.4e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY64022.1 - 3.7e-05 24.3 0.4 7.9e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 SnoaL-like domain Aldo_ket_red PF00248.21 KEY64023.1 - 5.3e-35 121.0 0.0 1.5e-33 116.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_3 PF13738.6 KEY64024.1 - 1.1e-19 70.9 0.0 1.8e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY64024.1 - 3e-17 62.8 0.0 2.3e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY64024.1 - 5.7e-13 48.7 0.1 2.9e-10 39.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KEY64024.1 - 3.4e-12 45.6 0.2 3.6e-11 42.2 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 KEY64024.1 - 8.3e-09 35.9 0.1 0.0018 18.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY64024.1 - 2.4e-07 30.9 0.0 2.2e-06 27.8 0.0 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEY64024.1 - 1e-06 28.2 0.2 4.5e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KEY64024.1 - 7.8e-06 25.2 0.4 0.0021 17.2 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEY64024.1 - 1.1e-05 24.4 0.3 0.00049 18.9 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 KEY64024.1 - 1.6e-05 24.3 0.0 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEY64024.1 - 4e-05 23.7 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KEY64024.1 - 0.0001 21.6 1.1 0.00036 19.7 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KEY64024.1 - 0.00014 22.2 0.0 0.049 14.1 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 KEY64024.1 - 0.00078 19.1 0.2 0.23 11.0 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEY64024.1 - 0.0011 18.9 0.1 0.093 12.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY64024.1 - 0.0021 17.4 0.2 0.0044 16.4 0.0 1.5 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KEY64024.1 - 0.0057 15.9 0.2 0.042 13.1 0.0 2.3 2 1 1 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 KEY64024.1 - 0.0077 15.6 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KEY64024.1 - 0.013 15.8 0.1 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 KEY64024.1 - 0.016 14.2 0.1 0.054 12.5 0.0 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein IlvN PF07991.12 KEY64024.1 - 0.045 13.3 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 KEY64024.1 - 0.082 12.9 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding XdhC_C PF13478.6 KEY64024.1 - 0.094 13.2 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DEAD PF00270.29 KEY64024.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ELFV_dehydrog PF00208.21 KEY64024.1 - 0.19 11.4 0.3 0.41 10.3 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 KEY64025.1 - 1.8e-26 92.1 4.6 3.3e-26 91.3 3.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY64025.1 - 3.8e-18 65.7 0.0 6.6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY64025.1 - 1.8e-06 27.6 0.0 0.0078 15.7 0.0 3.0 3 1 0 3 3 3 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY64025.1 - 0.0011 20.0 0.0 0.0026 18.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PIN PF01850.21 KEY64025.1 - 0.035 14.6 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 PIN domain 2-Hacid_dh_C PF02826.19 KEY64025.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KEY64026.1 - 9.5e-36 123.4 27.2 1.3e-35 123.0 27.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sensor PF13796.6 KEY64026.1 - 0.0044 17.1 14.0 0.0044 17.1 14.0 2.9 1 1 1 2 2 2 1 Putative sensor HpcH_HpaI PF03328.14 KEY64027.1 - 1.2e-40 139.0 0.0 1.6e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 KEY64027.1 - 0.027 13.9 0.9 0.27 10.6 0.1 2.6 3 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Zn_clus PF00172.18 KEY64028.1 - 2.4e-09 37.2 10.0 2.4e-09 37.2 10.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY64028.1 - 0.025 13.6 0.5 0.25 10.4 0.1 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain CREPT PF16566.5 KEY64028.1 - 0.057 13.6 0.7 6.8 6.9 0.2 2.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 KEY64028.1 - 0.098 13.0 0.2 1 9.7 0.1 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Clr5 PF14420.6 KEY64029.1 - 0.00018 21.6 0.1 0.00057 20.1 0.1 1.9 1 0 0 1 1 1 1 Clr5 domain Dynamin_N PF00350.23 KEY64030.1 - 1.3e-22 80.6 0.0 3e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEY64030.1 - 5.7e-14 52.0 0.6 6.1e-11 42.1 0.1 3.1 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 KEY64030.1 - 1.2e-07 31.8 0.0 4.6e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KEY64030.1 - 0.0019 18.0 0.0 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEY64030.1 - 0.0078 16.0 0.2 0.039 13.6 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEY64030.1 - 0.083 12.2 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family TniB PF05621.11 KEY64030.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KEY64030.1 - 0.13 12.7 0.1 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF883 PF05957.13 KEY64030.1 - 4.6 7.9 9.5 5.3 7.7 0.2 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FAD_binding_3 PF01494.19 KEY64031.1 - 3.2e-17 62.8 0.1 7.5e-17 61.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY64031.1 - 2.1e-08 34.2 0.6 4.9e-08 33.1 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY64031.1 - 1.8e-06 27.8 1.3 2.8e-06 27.2 1.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY64031.1 - 3.8e-05 24.2 0.7 0.00013 22.4 0.7 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY64031.1 - 4.3e-05 22.9 1.7 7.4e-05 22.1 1.7 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY64031.1 - 0.00029 20.3 0.1 0.012 14.9 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KEY64031.1 - 0.0013 17.9 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KEY64031.1 - 0.0016 17.9 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY64031.1 - 0.0016 17.6 3.6 0.0045 16.1 2.7 1.9 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 KEY64031.1 - 0.018 14.2 1.9 0.031 13.4 1.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KEY64031.1 - 0.036 13.9 0.8 0.076 12.9 0.8 1.5 1 0 0 1 1 1 0 Rossmann-like domain Trp_halogenase PF04820.14 KEY64031.1 - 0.042 12.7 1.5 0.73 8.6 0.9 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KEY64031.1 - 0.045 13.6 1.7 0.086 12.7 1.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KEY64031.1 - 0.11 12.6 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEY64031.1 - 0.18 11.8 0.5 0.32 11.0 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KEY64031.1 - 0.19 11.0 1.1 0.46 9.7 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY64031.1 - 0.61 8.7 4.1 0.25 10.0 1.7 1.5 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KEY64032.1 - 9.2e-25 87.3 28.1 4.7e-24 85.0 29.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.12 KEY64032.1 - 6.2 6.8 7.5 1.1 9.2 0.1 3.2 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC GST_N_2 PF13409.6 KEY64033.1 - 2.6e-19 69.3 0.0 7.8e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY64033.1 - 2.3e-10 40.3 0.0 2.5e-09 37.0 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY64033.1 - 0.0087 16.5 0.0 8.1 6.9 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY64033.1 - 0.022 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY64033.1 - 0.053 13.7 0.0 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain CBM_5_12_2 PF14600.6 KEY64033.1 - 0.095 12.6 0.8 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Cellulose-binding domain Aldo_ket_red PF00248.21 KEY64034.1 - 1.6e-41 142.5 0.0 2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Alliinase_C PF04864.13 KEY64034.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Allinase adh_short PF00106.25 KEY64035.1 - 9.3e-16 57.9 0.3 3.2e-15 56.1 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64035.1 - 1.4e-13 50.9 1.4 1.2e-12 47.9 1.4 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KEY64036.1 - 1.3e-53 182.4 0.0 1.7e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tri3 PF07428.11 KEY64037.1 - 4.5e-143 477.0 0.0 5.4e-143 476.8 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 KEY64037.1 - 0.00021 20.0 0.0 0.00084 18.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Fungal_trans_2 PF11951.8 KEY64038.1 - 2.3e-56 191.3 2.5 3e-56 190.9 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY64039.1 - 0.012 16.0 0.5 0.012 16.0 0.5 4.4 4 1 0 4 4 4 0 Zinc finger, C2H2 type Defensin_beta PF00711.19 KEY64039.1 - 0.46 10.5 5.6 1.1 9.3 0.4 2.7 3 0 0 3 3 3 0 Beta defensin zf-C2H2_4 PF13894.6 KEY64039.1 - 0.86 10.6 0.2 0.86 10.6 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger ketoacyl-synt PF00109.26 KEY64040.1 - 1.4e-56 191.9 0.3 3.7e-56 190.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY64040.1 - 2.9e-49 168.3 0.1 5.9e-49 167.3 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY64040.1 - 2.7e-44 151.6 0.0 4.8e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KEY64040.1 - 9.4e-36 123.4 0.4 2.2e-35 122.2 0.4 1.7 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KEY64040.1 - 7.8e-09 36.0 0.1 3.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY64040.1 - 1.5e-06 28.4 0.0 4.5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEY64040.1 - 2.3e-05 25.1 0.0 6.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.22 KEY64040.1 - 0.00015 21.8 0.0 0.0006 19.8 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.6 KEY64040.1 - 0.00046 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64040.1 - 0.0033 18.0 0.0 0.013 16.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEY64040.1 - 0.0066 16.4 0.8 0.035 14.1 0.1 2.6 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KEY64040.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEY64040.1 - 0.092 13.5 0.0 0.55 11.0 0.0 2.5 1 0 0 1 1 1 0 Methyltransferase domain Tri3 PF07428.11 KEY64041.1 - 7.1e-96 321.6 0.0 8.4e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 KEY64041.1 - 0.23 10.0 0.0 0.42 9.1 0.0 1.3 2 0 0 2 2 2 0 Alcohol acetyltransferase p450 PF00067.22 KEY64042.1 - 6.1e-74 249.4 0.0 7e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KEY64043.1 - 4.5e-183 608.1 3.3 5.3e-183 607.9 3.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1816 PF08846.10 KEY64043.1 - 0.0027 17.7 0.1 0.018 15.0 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1816) DUF2935 PF11155.8 KEY64043.1 - 0.0073 16.6 0.2 0.0073 16.6 0.2 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2935) TauD PF02668.16 KEY64045.1 - 6.9e-30 104.7 0.0 9e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEY64045.1 - 0.043 12.9 0.2 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 CsiD Recep_L_domain PF01030.24 KEY64045.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Receptor L domain Methyltransf_2 PF00891.18 KEY64046.1 - 3.2e-17 62.6 0.0 5.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KEY64046.1 - 0.0023 17.7 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEY64046.1 - 0.081 12.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Acetyltransf_7 PF13508.7 KEY64047.1 - 1.9e-06 28.2 0.0 4.3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY64047.1 - 1.2e-05 25.3 0.0 2.9e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY64047.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KEY64047.1 - 0.11 12.6 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KEY64048.1 - 0.014 15.6 4.6 0.03 14.4 4.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEY64049.1 - 5.1e-17 61.8 36.0 6.2e-15 55.0 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ODV-E18 PF10717.9 KEY64049.1 - 3.2 7.7 7.4 0.15 11.9 0.4 2.4 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Q_salvage PF10343.9 KEY64050.1 - 9.7e-101 337.0 0.0 1.2e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DNA_pol_delta_4 PF04081.13 KEY64051.1 - 2.3e-42 144.4 2.0 2.3e-42 144.4 2.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Trypan_PARP PF05887.11 KEY64051.1 - 0.078 13.0 2.5 0.11 12.5 2.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.32 KEY64052.1 - 2.9e-22 78.5 14.2 4.9e-09 36.7 1.6 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64052.1 - 1.7e-11 44.3 0.4 0.017 15.4 0.4 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L32p PF01783.23 KEY64052.1 - 1.4e-10 41.3 7.0 1.4e-10 41.3 7.0 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family Cytochrom_D1 PF02239.16 KEY64052.1 - 0.0039 15.8 0.0 0.012 14.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 KEY64052.1 - 0.0062 16.4 0.0 0.033 14.1 0.0 2.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEY64052.1 - 0.025 13.2 0.1 0.57 8.8 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KEY64052.1 - 0.037 13.3 0.0 0.35 10.1 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KEY64052.1 - 0.11 11.5 0.0 39 3.1 0.0 3.1 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KEY64052.1 - 0.17 10.7 0.6 0.33 9.8 0.2 1.7 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Septin PF00735.18 KEY64053.1 - 8.6e-110 366.4 0.2 1e-109 366.2 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KEY64053.1 - 4.8e-06 26.6 0.0 9.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY64053.1 - 2.7e-05 24.1 0.1 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEY64053.1 - 0.00046 19.8 0.3 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KEY64053.1 - 0.00052 19.4 0.0 0.00096 18.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KEY64053.1 - 0.017 15.1 0.2 3.6 7.6 0.0 2.4 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 KEY64053.1 - 0.044 14.3 0.1 0.08 13.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KEY64053.1 - 0.15 12.3 0.1 0.43 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain Glyco_hydro_72 PF03198.14 KEY64054.1 - 1.6e-108 362.7 0.5 2e-108 362.4 0.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KEY64054.1 - 1.5e-05 24.3 0.2 2.8e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4073 PF13285.6 KEY64054.1 - 0.014 15.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) Citrate_bind PF16114.5 KEY64055.1 - 9.4e-87 289.1 0.0 1.3e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KEY64055.1 - 3.1e-07 30.2 0.0 5.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KEY64055.1 - 0.00096 17.4 0.0 0.0014 16.8 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 KEY64056.1 - 1e-20 74.2 0.0 1.5e-17 63.8 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KEY64056.1 - 1.7e-19 70.3 0.0 5.2e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KEY64056.1 - 1.6e-14 54.0 0.4 3.2e-14 53.0 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 KEY64056.1 - 1.6e-05 24.7 0.0 0.00043 20.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DapB_N PF01113.20 KEY64056.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_L30 PF00327.20 KEY64057.1 - 7e-16 57.8 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 KEY64058.1 - 3.2e-60 202.8 0.2 5.2e-60 202.2 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KEY64058.1 - 1.4e-06 28.1 0.2 2.6e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.10 KEY64059.1 - 2.9e-25 88.2 0.5 5.3e-25 87.4 0.1 1.6 2 0 0 2 2 2 1 Cnl2/NKP2 family protein CENP-F_leu_zip PF10473.9 KEY64059.1 - 0.02 14.9 1.9 0.13 12.3 1.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KEY64059.1 - 0.067 12.1 1.7 0.1 11.5 0.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 KEY64059.1 - 0.077 13.3 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 KEY64059.1 - 0.091 12.9 0.7 0.39 10.8 0.7 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 KEY64059.1 - 0.097 12.5 2.8 0.12 12.2 0.2 2.2 2 1 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KEY64059.1 - 0.15 12.6 3.6 0.24 11.9 3.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KEY64059.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.4 2 1 0 2 2 2 0 Cell division protein ZapB ET PF01684.16 KEY64060.1 - 0.046 14.1 0.1 0.09 13.1 0.1 1.5 1 0 0 1 1 1 0 ET module COP23 PF14218.6 KEY64060.1 - 0.053 13.3 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 Circadian oscillating protein COP23 CENP-Q PF13094.6 KEY64061.1 - 5.1e-46 156.9 3.7 5.1e-46 156.9 3.7 2.5 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit NOA36 PF06524.12 KEY64062.1 - 1.7 7.9 3.8 2.5 7.3 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KEY64062.1 - 1.8 9.0 7.2 3.2 8.2 7.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KEY64062.1 - 2.9 8.3 4.9 4.5 7.7 4.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTP1_C1 PF10363.9 KEY64063.1 - 4e-23 81.7 0.2 1.2e-21 77.0 0.0 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KEY64063.1 - 1.1e-13 50.5 0.3 2.6e-13 49.4 0.3 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 PHAT PF09246.10 KEY64063.1 - 0.16 11.8 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 PHAT MOR2-PAG1_C PF14225.6 KEY64063.1 - 0.32 10.8 2.4 0.69 9.7 1.4 2.0 1 1 0 1 1 1 0 Cell morphogenesis C-terminal RIX1 PF08167.12 KEY64063.1 - 0.57 9.9 3.0 0.73 9.6 1.2 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis IBB PF01749.20 KEY64063.1 - 2.3 8.7 5.8 0.46 10.9 1.4 2.0 2 0 0 2 2 2 0 Importin beta binding domain OB_NTP_bind PF07717.16 KEY64065.1 - 3.3e-23 81.8 0.0 1.5e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEY64065.1 - 5.4e-18 65.2 0.4 1.4e-17 63.9 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEY64065.1 - 4.9e-11 42.9 0.0 3e-10 40.4 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY64065.1 - 1e-07 31.9 0.1 2.3e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY64065.1 - 2.4e-05 24.6 0.0 6.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEY64065.1 - 0.00091 18.9 0.2 0.0029 17.2 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KEY64065.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY64065.1 - 0.0084 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEY64065.1 - 0.0091 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KEY64065.1 - 0.066 13.2 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 KEY64065.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Spore_IV_A PF09547.10 KEY64065.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) PRMT5_TIM PF17285.2 KEY64066.1 - 2.3e-70 236.7 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KEY64066.1 - 5.9e-67 224.8 0.0 1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KEY64066.1 - 5.1e-58 195.9 0.0 7.5e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KEY64066.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Hydrolase_4 PF12146.8 KEY64067.1 - 2e-17 63.3 0.0 2.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY64067.1 - 2.8e-17 64.1 7.5 4.1e-17 63.5 7.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY64067.1 - 3.2e-14 53.2 0.2 1.1e-12 48.2 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY64067.1 - 7.5e-06 25.6 0.2 0.00038 20.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KEY64067.1 - 0.0033 17.6 0.2 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain DUF1749 PF08538.10 KEY64067.1 - 0.0038 16.4 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 KEY64067.1 - 0.029 14.2 1.7 0.31 10.8 1.7 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KEY64067.1 - 0.084 12.6 0.3 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein AXE1 PF05448.12 KEY64067.1 - 0.31 9.7 0.8 1.3 7.7 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Aminotran_5 PF00266.19 KEY64068.1 - 1.1e-27 97.0 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.11 KEY64069.1 - 5.2e-130 433.3 0.3 5.2e-130 433.3 0.3 3.3 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 KEY64069.1 - 3.9e-40 137.3 12.9 7.8e-40 136.4 9.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KEY64069.1 - 2.3e-33 113.7 4.1 6.6e-33 112.2 4.1 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KEY64069.1 - 2.1e-27 95.0 0.8 2.1e-27 95.0 0.8 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KEY64069.1 - 9.6e-20 69.8 2.8 2.7e-19 68.4 2.8 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KEY64069.1 - 4e-10 39.5 0.3 2e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Hemocyanin_M PF00372.19 KEY64069.1 - 0.043 13.0 0.1 0.14 11.3 0.1 1.8 1 1 0 1 1 1 0 Hemocyanin, copper containing domain DUF3385 PF11865.8 KEY64069.1 - 0.073 13.0 10.0 0.34 10.8 0.0 4.7 6 1 0 7 7 7 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KEY64069.1 - 0.26 11.9 2.5 3.7 8.2 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Zn_clus PF00172.18 KEY64070.1 - 5.2e-07 29.7 8.0 8.7e-07 29.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KEY64071.1 - 1.7e-35 122.4 0.0 3.7e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY64071.1 - 2.1e-21 76.4 0.0 4.8e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEY64071.1 - 3.8e-19 68.7 0.0 7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEY64071.1 - 0.014 15.4 0.0 0.065 13.2 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEY64071.1 - 0.04 14.2 0.1 0.4 11.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF3984 PF13136.6 KEY64072.1 - 2.4 7.5 10.4 6 6.2 10.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) KxDL PF10241.9 KEY64073.1 - 3.7e-33 113.7 1.8 5.1e-33 113.2 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 KEY64073.1 - 0.075 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism UPF0242 PF06785.11 KEY64073.1 - 0.19 11.8 3.5 0.26 11.3 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KEY64073.1 - 1.4 9.3 10.2 2.1 8.7 10.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SNRNP27 PF08648.12 KEY64074.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Cir_N PF10197.9 KEY64076.1 - 5.7e-08 32.8 2.0 5.7e-08 32.8 2.0 4.8 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2599 PF10783.9 KEY64076.1 - 0.08 13.6 0.2 0.08 13.6 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2599) AAA PF00004.29 KEY64077.1 - 2.3e-50 170.4 0.0 9.2e-39 132.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY64077.1 - 2.4e-09 37.6 0.0 0.00035 20.8 0.0 3.7 2 2 2 4 4 4 1 AAA domain AAA_16 PF13191.6 KEY64077.1 - 1.3e-08 35.4 0.0 0.0044 17.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KEY64077.1 - 2.4e-08 33.6 0.1 6.5e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain ATPase_2 PF01637.18 KEY64077.1 - 1.2e-07 31.9 0.1 0.062 13.2 0.0 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 KEY64077.1 - 2.5e-07 30.2 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KEY64077.1 - 1.6e-06 28.2 0.0 0.0016 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEY64077.1 - 6.2e-06 26.4 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KEY64077.1 - 9e-06 25.7 0.0 0.086 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KEY64077.1 - 9.1e-06 25.9 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KEY64077.1 - 1.4e-05 24.8 0.1 0.0004 20.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KEY64077.1 - 2.6e-05 24.8 0.0 0.089 13.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KEY64077.1 - 3.3e-05 23.7 0.7 0.12 12.2 0.1 3.5 3 1 1 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEY64077.1 - 6.4e-05 23.3 0.0 0.09 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KEY64077.1 - 0.00037 20.0 1.0 0.0054 16.1 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEY64077.1 - 0.001 18.6 0.6 0.12 11.9 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEY64077.1 - 0.0013 18.5 0.0 0.59 9.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 KEY64077.1 - 0.0019 18.2 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KEY64077.1 - 0.0022 17.9 0.5 11 5.9 0.0 3.8 5 0 0 5 5 3 0 NACHT domain AAA_24 PF13479.6 KEY64077.1 - 0.0023 17.7 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KEY64077.1 - 0.0078 15.6 0.6 0.017 14.5 0.2 1.7 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 KEY64077.1 - 0.0097 16.2 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KEY64077.1 - 0.014 15.1 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KEY64077.1 - 0.016 14.3 0.0 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KEY64077.1 - 0.03 14.8 0.3 0.45 11.0 0.1 2.6 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 KEY64077.1 - 0.033 13.8 0.4 3.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEY64077.1 - 0.036 13.8 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEY64077.1 - 0.042 13.0 0.8 1.9 7.6 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_11 PF13086.6 KEY64077.1 - 0.055 13.2 0.1 0.7 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF759 PF05537.11 KEY64077.1 - 0.076 11.9 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) PhoH PF02562.16 KEY64077.1 - 0.1 12.0 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 KEY64077.1 - 0.16 12.4 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KEY64077.1 - 0.17 11.3 0.1 7.9 5.8 0.1 2.8 2 1 0 2 2 2 0 Bacterial TniB protein RasGEF PF00617.19 KEY64078.1 - 2.4e-46 158.1 0.2 3.8e-46 157.5 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEY64078.1 - 1.6e-12 47.6 0.1 3.6e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S2 PF00318.20 KEY64079.1 - 2.4e-25 89.1 0.1 4.7e-14 52.2 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KEY64079.1 - 1.4e-05 26.3 9.9 2.5e-05 25.5 9.9 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 KEY64080.1 - 4.2e-22 78.2 0.3 4.2e-22 78.2 0.3 2.2 2 1 1 3 3 3 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 KEY64081.1 - 2.4e-107 359.4 0.0 2.6e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 KEY64082.1 - 2.2e-75 253.1 0.4 2.2e-75 253.1 0.4 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEY64082.1 - 2.2e-20 72.8 2.0 2.2e-20 72.8 2.0 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HHH_5 PF14520.6 KEY64082.1 - 0.029 15.0 0.1 0.88 10.2 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Band_7 PF01145.25 KEY64083.1 - 6.9e-28 97.8 3.3 1.1e-27 97.2 3.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KEY64083.1 - 0.0084 15.8 0.5 0.014 15.1 0.5 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family ANAPC10 PF03256.16 KEY64084.1 - 2e-50 171.0 0.0 3.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) GCIP PF13324.6 KEY64084.1 - 0.0014 18.3 0.2 0.0021 17.7 0.2 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting NAT PF04768.13 KEY64084.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Dioxygenase_C PF00775.21 KEY64086.1 - 2.4e-09 36.9 0.1 4.1e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Glyco_hydro_61 PF03443.14 KEY64087.1 - 6.1e-49 166.7 0.0 7.1e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 KEY64088.1 - 7.5e-21 74.8 0.0 1.8e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KEY64088.1 - 0.00011 21.7 0.0 0.0061 15.9 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KEY64088.1 - 0.00076 18.8 0.4 0.32 10.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY64088.1 - 0.00077 18.8 1.1 0.17 11.1 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY64088.1 - 0.0049 17.4 1.0 0.02 15.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY64088.1 - 0.006 15.7 0.3 1.3 8.0 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KEY64088.1 - 0.034 12.9 0.9 1.3 7.6 0.2 2.4 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KEY64088.1 - 0.13 11.6 0.1 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KEY64088.1 - 0.15 11.1 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KEY64088.1 - 0.19 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase bZIP_1 PF00170.21 KEY64089.1 - 3.3e-06 27.1 2.7 1e-05 25.5 2.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY64089.1 - 7.5e-05 22.7 2.8 7.5e-05 22.7 2.8 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY64089.1 - 0.01 16.3 0.7 0.01 16.3 0.7 3.0 4 0 0 4 4 4 0 bZIP Maf transcription factor DUF908 PF06012.12 KEY64089.1 - 1.7 8.0 4.7 2.4 7.5 4.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Goodbye PF17109.5 KEY64090.1 - 5.9e-29 101.0 0.0 1.9e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KEY64090.1 - 1e-09 39.0 0.3 1.5e-08 35.2 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KEY64090.1 - 9.5e-08 31.6 5.4 0.01 15.9 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY64090.1 - 1.7e-07 31.4 11.0 0.011 16.1 0.2 5.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY64090.1 - 1.4e-06 27.8 2.3 0.0035 17.1 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 KEY64090.1 - 0.0012 19.1 0.0 0.0058 16.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEY64090.1 - 0.0021 18.0 0.8 0.023 14.6 0.0 3.1 4 0 0 4 4 4 1 NACHT domain TPR_8 PF13181.6 KEY64090.1 - 0.0025 17.9 9.5 0.18 12.1 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY64090.1 - 0.0059 17.1 8.9 0.021 15.4 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY64090.1 - 0.011 16.4 3.4 0.096 13.4 0.0 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY64090.1 - 0.053 13.6 4.0 1.6 8.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatamer_beta_C PF07718.12 KEY64090.1 - 0.13 12.2 0.5 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Coatomer beta C-terminal region TPR_14 PF13428.6 KEY64090.1 - 0.34 11.8 12.7 2.2 9.3 0.0 6.2 6 1 0 6 6 5 0 Tetratricopeptide repeat FYVE PF01363.21 KEY64090.1 - 0.4 10.9 5.2 0.87 9.8 5.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger Gamma-thionin PF00304.20 KEY64091.1 - 0.013 15.8 14.6 0.05 13.9 3.0 2.3 2 0 0 2 2 2 0 Gamma-thionin family Colipase-like PF15083.6 KEY64091.1 - 0.086 13.0 3.8 0.68 10.1 0.5 2.1 2 0 0 2 2 2 0 Colipase-like Colipase PF01114.18 KEY64091.1 - 0.31 10.8 17.0 0.2 11.4 6.1 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain Nodulin_late PF07127.11 KEY64091.1 - 0.66 10.4 3.7 7 7.1 0.4 2.3 2 0 0 2 2 2 0 Late nodulin protein Prokineticin PF06607.11 KEY64091.1 - 2.2 8.7 11.1 2.2 8.7 2.0 2.5 2 0 0 2 2 2 0 Prokineticin Abhydrolase_6 PF12697.7 KEY64092.1 - 4.9e-22 79.6 0.8 6.4e-22 79.3 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY64092.1 - 1.1e-16 61.3 0.1 1.9e-14 54.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY64092.1 - 1.1e-08 34.7 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KEY64092.1 - 0.032 14.1 0.2 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase SGL PF08450.12 KEY64093.1 - 0.0017 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF1921 PF09081.10 KEY64093.1 - 0.24 11.7 2.3 17 5.7 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) HET PF06985.11 KEY64096.1 - 1.5e-34 119.4 0.1 2.7e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KEY64096.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MAGE_N PF12440.8 KEY64097.1 - 0.18 12.5 5.6 0.21 12.3 5.6 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal HECT PF00632.25 KEY64098.1 - 3.2e-73 246.9 0.0 5.4e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KEY64098.1 - 0.00042 20.3 1.4 1.5 9.3 0.1 4.6 3 0 0 3 3 3 1 HEAT repeat SDA1 PF05285.12 KEY64098.1 - 0.0041 16.6 20.0 0.0041 16.6 20.0 2.6 2 0 0 2 2 2 1 SDA1 DUF4684 PF15736.5 KEY64098.1 - 0.009 14.7 12.1 0.022 13.5 12.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4684) DUF2013 PF09431.10 KEY64098.1 - 0.055 13.6 0.1 0.2 11.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) CLASP_N PF12348.8 KEY64098.1 - 0.15 11.6 0.7 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.23 KEY64098.1 - 0.2 11.8 15.5 0.49 10.5 0.1 6.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Zip PF02535.22 KEY64098.1 - 0.8 8.9 7.9 2.4 7.3 7.9 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter HEAT_EZ PF13513.6 KEY64098.1 - 1.2 9.7 6.2 8.4 7.0 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF913 PF06025.12 KEY64098.1 - 6.4 5.7 11.5 0.35 9.8 4.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) E1_dh PF00676.20 KEY64099.1 - 1.5e-87 293.3 0.0 1.8e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KEY64099.1 - 0.00011 22.0 0.1 0.0019 18.0 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KEY64099.1 - 0.046 12.9 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.18 KEY64100.1 - 1.5e-74 250.2 0.0 3.9e-62 209.6 0.0 2.0 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KEY64100.1 - 7.9e-16 58.5 0.0 2.7e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY64100.1 - 3.8e-14 52.8 0.0 5.6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64100.1 - 4.8e-13 49.6 0.0 1.4e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY64100.1 - 9.9e-11 42.3 0.0 1.8e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY64100.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEY64100.1 - 0.022 14.6 0.0 0.087 12.7 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 KEY64100.1 - 0.051 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MTS PF05175.14 KEY64100.1 - 0.088 12.4 0.0 0.35 10.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF2433 PF10360.9 KEY64101.1 - 1.2e-49 167.5 0.0 1.8e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KEY64101.1 - 0.00011 22.8 0.0 0.00041 20.9 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY64101.1 - 0.0031 17.7 0.0 0.01 16.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zds_C PF08632.10 KEY64102.1 - 4.2e-30 103.3 0.7 7.6e-30 102.4 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Complex1_30kDa PF00329.19 KEY64103.1 - 9.9e-45 152.1 0.0 1.4e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 KEY64104.1 - 6.2e-20 70.7 12.2 1.3e-19 69.7 12.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KEY64104.1 - 8.9e-08 31.9 0.0 4.5e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KEY64104.1 - 4.2e-07 29.7 7.6 4.2e-07 29.7 7.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KEY64104.1 - 4.4e-05 23.0 3.3 4.4e-05 23.0 3.3 3.6 2 1 1 3 3 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KEY64104.1 - 0.00037 20.8 9.8 0.00094 19.5 9.8 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KEY64104.1 - 0.0072 16.2 8.8 0.15 11.9 9.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SET_assoc PF11767.8 KEY64104.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.25 KEY64104.1 - 0.11 12.4 10.3 0.25 11.3 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KEY64104.1 - 0.11 12.6 4.8 0.24 11.5 4.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 KEY64104.1 - 0.12 12.3 4.9 0.21 11.5 4.9 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KEY64104.1 - 0.18 12.0 5.0 0.47 10.6 5.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Ion_trans_2 PF07885.16 KEY64105.1 - 7.7e-32 109.1 28.6 1.8e-17 63.1 4.4 3.3 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KEY64105.1 - 0.0086 15.3 2.3 0.0086 15.3 2.3 3.4 2 1 0 2 2 2 1 Ion transport protein Filament PF00038.21 KEY64107.1 - 1.4e-07 31.4 138.6 5.9e-06 26.1 39.2 7.8 1 1 5 6 6 6 2 Intermediate filament protein ATG16 PF08614.11 KEY64107.1 - 0.00028 21.2 27.7 0.00028 21.2 27.7 10.2 2 2 5 8 8 4 2 Autophagy protein 16 (ATG16) FAM184 PF15665.5 KEY64107.1 - 0.0014 18.4 13.1 0.0014 18.4 13.1 8.8 1 1 5 8 8 8 5 Family with sequence similarity 184, A and B Sec2p PF06428.11 KEY64107.1 - 0.0016 18.4 13.3 0.0016 18.4 13.3 12.1 5 4 7 15 15 14 3 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 KEY64107.1 - 0.0028 16.6 23.5 0.0028 16.6 23.5 8.5 1 1 7 9 9 7 6 Spc7 kinetochore protein AAA_13 PF13166.6 KEY64107.1 - 0.0034 16.1 24.9 0.0034 16.1 24.9 5.6 1 1 6 7 7 6 3 AAA domain DUF4201 PF13870.6 KEY64107.1 - 0.0058 16.4 15.5 0.0058 16.4 15.5 9.5 2 1 6 9 9 8 2 Domain of unknown function (DUF4201) DUF724 PF05266.14 KEY64107.1 - 0.011 15.6 3.0 0.011 15.6 3.0 10.0 2 2 10 12 12 10 0 Protein of unknown function (DUF724) Rsa3 PF14615.6 KEY64107.1 - 0.14 11.7 2.2 13 5.5 0.3 3.5 2 0 0 2 2 2 0 Ribosome-assembly protein 3 Baculo_PEP_C PF04513.12 KEY64107.1 - 4.6 7.3 76.8 0.16 12.0 0.7 10.0 3 2 8 11 11 11 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KEY64107.1 - 7.3 6.8 77.5 0.52 10.5 7.0 9.2 4 2 2 8 8 8 0 Fibrinogen alpha/beta chain family PTPA PF03095.15 KEY64109.1 - 2.3e-116 388.5 0.0 2.7e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1180 PF06679.12 KEY64113.1 - 0.3 11.5 2.3 0.46 10.9 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) adh_short PF00106.25 KEY64114.1 - 7.7e-27 94.0 0.0 3.1e-25 88.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64114.1 - 1e-18 67.7 0.1 2.3e-17 63.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY64114.1 - 0.0017 17.9 0.1 0.0044 16.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY64114.1 - 0.0028 17.6 0.1 0.0059 16.5 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF3425 PF11905.8 KEY64115.1 - 5e-18 65.3 0.0 9.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) COX14 PF14880.6 KEY64116.1 - 0.3 11.0 3.8 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Velvet PF11754.8 KEY64118.1 - 3.1e-42 145.3 2.2 5.5e-32 111.7 0.8 2.2 1 1 1 2 2 2 2 Velvet factor Acetyltransf_1 PF00583.25 KEY64119.1 - 2e-09 37.7 0.0 2.7e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY64119.1 - 3e-08 33.6 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY64119.1 - 6.1e-07 29.8 0.0 9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY64119.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Tim17 PF02466.19 KEY64120.1 - 3e-31 108.1 9.2 4.4e-31 107.5 9.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.18 KEY64121.1 - 6.4e-51 173.2 0.1 4.6e-26 91.6 0.0 4.3 4 1 0 4 4 4 3 Asparaginase bZIP_1 PF00170.21 KEY64121.1 - 6.5e-07 29.4 0.8 6.5e-07 29.4 0.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor CENP-F_leu_zip PF10473.9 KEY64121.1 - 0.089 12.8 0.4 0.15 12.1 0.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KEY64121.1 - 0.24 11.5 2.3 0.74 9.9 2.3 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Pkinase PF00069.25 KEY64122.1 - 1e-31 110.3 0.0 9.5e-26 90.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64122.1 - 8.2e-19 67.9 0.0 2.4e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF641 PF04859.12 KEY64122.1 - 0.011 16.1 0.7 0.018 15.3 0.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 KEY64122.1 - 0.031 14.5 6.9 0.078 13.2 6.9 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MLTR_LBD PF17765.1 KEY64122.1 - 0.054 13.6 1.9 0.14 12.3 1.9 1.7 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain GAS PF13851.6 KEY64122.1 - 0.17 11.2 4.3 0.29 10.4 4.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 KEY64122.1 - 0.18 12.0 6.8 0.44 10.8 6.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain TSC22 PF01166.18 KEY64122.1 - 0.25 11.7 2.9 4.2 7.7 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.11 KEY64122.1 - 0.26 10.1 3.5 0.46 9.3 3.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KEY64122.1 - 1.7 9.0 8.7 2 8.8 2.3 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4140 PF13600.6 KEY64122.1 - 2 8.9 8.2 3.1 8.3 6.6 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GBP_C PF02841.14 KEY64122.1 - 2 7.7 6.4 3 7.2 6.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Complex1_LYR PF05347.15 KEY64123.1 - 0.00025 21.1 0.1 0.00099 19.1 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF982 PF06169.12 KEY64124.1 - 0.035 14.1 0.2 0.073 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF982) BLM10_mid PF16507.5 KEY64125.1 - 2.2e-197 656.9 0.0 3.1e-197 656.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KEY64125.1 - 2.7e-28 97.7 0.0 1e-27 95.8 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KEY64125.1 - 2.2e-21 75.9 0.1 6.6e-21 74.4 0.1 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal AP_endonuc_2_N PF07582.12 KEY64125.1 - 0.005 16.5 0.0 0.02 14.6 0.0 2.0 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus HEAT_EZ PF13513.6 KEY64125.1 - 0.074 13.6 2.4 2.2 8.9 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 KEY64125.1 - 0.18 12.1 0.6 28 5.3 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat A_deaminase PF00962.22 KEY64126.1 - 3.5e-22 79.2 0.0 1.8e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KEY64126.1 - 0.18 12.1 0.0 0.59 10.5 0.0 1.8 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SRP40_C PF05022.12 KEY64128.1 - 3.2e-19 69.6 0.6 1.2e-18 67.8 0.6 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain Rsm1 PF08600.10 KEY64129.1 - 2.5e-27 94.9 0.2 2.5e-27 94.9 0.2 2.4 2 1 1 3 3 3 1 Rsm1-like zf-C3HC PF07967.13 KEY64129.1 - 8.2e-26 90.6 2.2 7.8e-20 71.3 1.0 3.2 2 1 0 2 2 2 2 C3HC zinc finger-like BIR PF00653.21 KEY64129.1 - 9e-05 23.1 0.1 0.0048 17.5 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain FAD-oxidase_C PF02913.19 KEY64129.1 - 0.08 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain MMR_HSR1 PF01926.23 KEY64130.1 - 3.3e-16 59.4 0.0 5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEY64130.1 - 1.8e-07 31.4 0.2 0.00096 19.2 0.3 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KEY64130.1 - 0.00017 21.6 0.0 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEY64130.1 - 0.00018 21.1 0.0 0.00054 19.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KEY64130.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 KEY64130.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KEY64130.1 - 0.019 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 KEY64130.1 - 0.044 14.0 0.2 0.41 10.9 0.1 2.5 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KEY64130.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 AIG1 family AAA_29 PF13555.6 KEY64130.1 - 0.085 12.6 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain PPV_E1_C PF00519.17 KEY64130.1 - 0.21 10.4 0.0 0.8 8.5 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase IIGP PF05049.13 KEY64130.1 - 0.25 10.4 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) 2OG-FeII_Oxy_2 PF13532.6 KEY64131.1 - 2e-31 109.7 0.0 3.1e-31 109.1 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.25 KEY64132.1 - 5.3e-64 216.6 0.0 6.4e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.7 KEY64134.1 - 5.9e-28 97.2 4.9 1.9e-26 92.3 1.2 3.9 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEY64134.1 - 4.8e-08 33.1 22.3 2.5e-06 27.6 3.0 4.4 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY64134.1 - 1.3e-05 25.4 10.1 3.2e-05 24.2 4.3 3.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KEY64134.1 - 0.0026 18.4 21.1 0.67 10.9 0.6 5.8 6 0 0 6 6 6 3 C2H2-type zinc finger SnoaL_2 PF12680.7 KEY64134.1 - 0.069 13.8 0.2 0.24 12.0 0.1 1.9 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.12 KEY64134.1 - 0.19 10.2 1.8 6.3 5.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KEY64134.1 - 6.2 7.5 23.9 5.5 7.7 0.3 5.3 4 1 1 5 5 5 0 Zinc finger, C2H2 type EPSP_synthase PF00275.20 KEY64135.1 - 3e-128 428.1 0.0 1.7e-127 425.6 0.0 2.0 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KEY64135.1 - 2.1e-101 338.5 0.0 3.3e-101 337.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KEY64135.1 - 3.7e-58 197.5 0.0 6.5e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KEY64135.1 - 2.6e-37 128.4 0.0 6.3e-36 123.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KEY64135.1 - 6.6e-23 80.8 0.0 3.3e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KEY64135.1 - 3.9e-07 30.0 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KEY64135.1 - 3.2e-06 26.8 0.9 8.6e-06 25.4 0.2 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KEY64135.1 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KEY64135.1 - 0.11 12.9 0.0 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KEY64135.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KEY64136.1 - 2.6e-10 40.2 13.0 0.0075 16.7 1.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY64136.1 - 6.1e-05 23.5 9.2 0.92 10.5 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger TRAPPC-Trs85 PF12739.7 KEY64136.1 - 0.029 13.4 3.3 0.056 12.4 3.3 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SGIII PF15467.6 KEY64136.1 - 0.76 9.0 2.7 1.2 8.3 2.7 1.2 1 0 0 1 1 1 0 Secretogranin-3 zf-Di19 PF05605.12 KEY64136.1 - 1.6 9.1 5.3 3.5 8.0 1.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-T_C PF15511.6 KEY64137.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KEY64137.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KEY64137.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KEY64137.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KEY64137.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KEY64137.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEY64137.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KEY64137.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KEY64137.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 KEY64138.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KEY64138.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KEY64138.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KEY64138.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KEY64138.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KEY64138.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEY64138.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.17 KEY64139.1 - 4e-87 292.0 0.0 6.6e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEY64139.1 - 7e-68 228.1 0.7 1.4e-67 227.1 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KEY64139.1 - 8.4e-37 127.2 1.9 3.2e-35 122.0 0.5 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KEY64139.1 - 4.8e-31 107.8 0.0 2e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEY64139.1 - 2.9e-18 65.8 0.0 1.7e-17 63.3 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.10 KEY64140.1 - 5.6e-73 245.4 5.9 8.3e-73 244.8 5.9 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KEY64140.1 - 1.7e-47 161.2 0.5 1.7e-47 161.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) GET2 PF08690.10 KEY64140.1 - 0.021 14.5 1.8 0.046 13.4 1.8 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Ank_2 PF12796.7 KEY64141.1 - 8.3e-43 144.9 0.6 1.4e-15 57.6 0.1 7.5 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY64141.1 - 4.1e-30 103.7 1.6 1.4e-06 28.7 0.1 9.7 9 1 1 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY64141.1 - 1e-28 96.1 5.4 9.8e-05 22.5 0.0 11.7 13 0 0 13 13 13 5 Ankyrin repeat Ank_5 PF13857.6 KEY64141.1 - 6e-19 67.9 8.8 8.1e-06 26.0 0.0 8.6 6 2 5 11 11 11 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY64141.1 - 3.4e-18 65.2 16.5 6.8e-06 26.3 0.2 9.6 10 1 0 10 10 10 3 Ankyrin repeat Clr5 PF14420.6 KEY64141.1 - 0.0002 21.5 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain ILVD_EDD PF00920.21 KEY64142.1 - 3.2e-155 517.7 0.7 3.7e-155 517.5 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family ADH_zinc_N PF00107.26 KEY64143.1 - 2e-26 92.5 0.1 3.4e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY64143.1 - 1.3e-16 60.5 0.1 1.7e-13 50.4 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KEY64143.1 - 0.0001 21.9 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY64143.1 - 0.005 17.9 0.1 0.008 17.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEY64143.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Pyr_redox PF00070.27 KEY64143.1 - 0.056 14.0 0.1 0.53 10.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY64143.1 - 0.066 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_43 PF04616.14 KEY64146.1 - 5.1e-40 137.6 5.5 5.8e-40 137.4 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 KEY64147.1 - 9.4e-69 232.3 0.0 1.1e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fez1 PF06818.15 KEY64148.1 - 0.00022 21.8 14.9 0.00022 21.8 14.9 4.7 1 1 3 4 4 4 2 Fez1 FPP PF05911.11 KEY64148.1 - 0.00053 18.3 33.5 0.00053 18.3 33.5 3.4 2 1 1 3 3 3 2 Filament-like plant protein, long coiled-coil GIT_CC PF16559.5 KEY64148.1 - 0.035 14.0 0.9 0.035 14.0 0.9 6.2 6 3 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor HOOK PF05622.12 KEY64148.1 - 0.11 10.6 100.7 0.019 13.1 8.0 3.1 2 1 1 3 3 3 0 HOOK protein DUF1664 PF07889.12 KEY64148.1 - 8.1 6.5 59.9 0.065 13.3 7.0 5.8 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) Trp_DMAT PF11991.8 KEY64150.1 - 6.5e-87 292.3 0.0 8e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Amidohydro_2 PF04909.14 KEY64152.1 - 3.3e-35 122.3 3.2 4.9e-35 121.7 1.5 1.7 1 1 1 2 2 2 1 Amidohydrolase SnoaL_4 PF13577.6 KEY64153.1 - 0.066 13.3 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.7 KEY64154.1 - 5.7e-21 76.1 0.0 7.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY64154.1 - 6.7e-20 71.4 0.0 1.5e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY64154.1 - 3.1e-18 66.4 0.0 7.2e-15 55.3 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KEY64154.1 - 8.4e-07 29.0 0.0 0.0037 17.2 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.16 KEY64154.1 - 9.3e-05 22.3 0.1 0.29 10.9 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KEY64154.1 - 9.6e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 KEY64154.1 - 0.00016 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 KEY64154.1 - 0.002 17.7 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEY64154.1 - 0.018 14.5 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KEY64154.1 - 0.028 14.1 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_3 PF07859.13 KEY64154.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Humanin PF15040.6 KEY64154.1 - 0.066 12.7 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Humanin family LIDHydrolase PF10230.9 KEY64154.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CoA_transf_3 PF02515.17 KEY64155.1 - 4.5e-40 137.9 0.0 2e-37 129.2 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Spidroin_N PF16763.5 KEY64155.1 - 0.0069 16.4 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term Dioxygenase_C PF00775.21 KEY64156.1 - 1e-47 161.9 0.0 1.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEY64156.1 - 1.4e-26 92.2 0.1 2.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEY64156.1 - 1.6e-05 25.0 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KEY64156.1 - 0.039 13.9 0.0 3.2 7.8 0.0 2.7 3 0 0 3 3 3 0 CarboxypepD_reg-like domain RHH_8 PF17723.1 KEY64156.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Aldo_ket_red PF00248.21 KEY64158.1 - 2.8e-33 115.4 0.0 3.4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNR_N PF08343.10 KEY64158.1 - 0.073 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Dec-1 PF04624.14 KEY64158.1 - 0.28 11.1 0.5 30 4.6 0.1 2.3 2 0 0 2 2 2 0 Dec-1 repeat Fungal_trans PF04082.18 KEY64159.1 - 7.5e-12 44.8 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64159.1 - 0.0031 17.6 7.6 0.0063 16.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_10 PF00331.20 KEY64160.1 - 9.5e-100 333.8 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Beta-prism_lec PF16458.5 KEY64160.1 - 0.19 11.7 1.7 6.9 6.7 0.2 2.3 2 0 0 2 2 2 0 Beta-prism lectin COesterase PF00135.28 KEY64161.1 - 3.2e-96 323.3 0.0 3.7e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY64161.1 - 8.2e-06 25.8 0.2 0.00013 21.9 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY64161.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DCAF15_WD40 PF14939.6 KEY64161.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF3147 PF11345.8 KEY64162.1 - 0.0096 16.3 0.7 0.0096 16.3 0.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3147) p450 PF00067.22 KEY64163.1 - 1.7e-77 261.1 0.0 2.4e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.6 KEY64164.1 - 9.9e-47 159.4 1.8 3.3e-46 157.7 0.7 2.2 2 0 0 2 2 2 1 Prion-inhibition and propagation FA_desaturase PF00487.24 KEY64164.1 - 1.6e-08 34.7 27.0 3.1e-08 33.8 27.0 1.5 1 0 0 1 1 1 1 Fatty acid desaturase NACHT PF05729.12 KEY64164.1 - 1.8e-05 24.8 0.1 8.3e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 KEY64164.1 - 0.0045 17.5 0.1 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KEY64164.1 - 0.0068 16.8 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEY64164.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY64164.1 - 0.041 13.6 0.9 0.11 12.2 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEY64164.1 - 0.19 12.1 0.1 0.43 11.0 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 KEY64164.1 - 0.3 9.7 1.9 0.18 10.4 0.1 1.4 2 0 0 2 2 2 0 AAA domain NmrA PF05368.13 KEY64165.1 - 1.5e-13 50.9 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY64165.1 - 0.0003 20.7 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEY64165.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY64165.1 - 0.022 14.2 0.1 0.062 12.8 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY64165.1 - 0.13 12.2 0.1 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 KR domain Abhydrolase_1 PF00561.20 KEY64167.1 - 2.3e-13 50.4 1.1 4.8e-12 46.1 0.7 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY64167.1 - 3.5e-13 50.7 9.3 5.4e-13 50.1 9.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY64167.1 - 5.8e-08 32.3 1.1 1.2e-07 31.3 0.9 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY64167.1 - 4e-06 25.7 0.0 6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Lactamase_B PF00753.27 KEY64168.1 - 1.4e-14 54.6 0.6 3.3e-14 53.4 0.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY64168.1 - 0.00035 20.1 0.1 0.00062 19.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sulfotransfer_4 PF17784.1 KEY64168.1 - 0.05 13.4 0.3 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Sulfotransferase domain Pyr_redox_2 PF07992.14 KEY64169.1 - 4e-14 52.6 0.0 4.2e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY64169.1 - 0.0002 21.4 0.0 0.0067 16.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEY64169.1 - 0.0014 18.3 0.3 0.003 17.2 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEY64169.1 - 0.035 13.4 0.2 0.072 12.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KEY64169.1 - 0.036 13.1 0.5 0.061 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEY64169.1 - 0.075 12.3 0.1 8 5.6 0.3 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY64169.1 - 0.087 11.9 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KEY64169.1 - 0.11 11.2 0.0 0.32 9.6 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Aminotran_1_2 PF00155.21 KEY64169.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II Sacchrp_dh_NADP PF03435.18 KEY64169.1 - 0.17 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 KEY64169.1 - 0.21 10.6 0.1 1.2 8.1 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ABC_tran PF00005.27 KEY64170.1 - 9.8e-28 97.4 0.1 1.5e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KEY64170.1 - 3.8e-25 88.5 28.8 3.8e-25 88.5 28.8 1.4 2 0 0 2 2 1 1 ABC-2 type transporter SMC_N PF02463.19 KEY64170.1 - 9.4e-06 25.2 0.0 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY64170.1 - 1.9e-05 25.1 0.1 4.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KEY64170.1 - 3.2e-05 23.9 0.0 0.036 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KEY64170.1 - 0.00024 20.7 0.2 0.00044 19.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEY64170.1 - 0.00053 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KEY64170.1 - 0.00057 19.6 0.2 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY64170.1 - 0.00084 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEY64170.1 - 0.0055 15.8 0.1 0.0097 15.0 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 KEY64170.1 - 0.0065 17.0 0.4 0.012 16.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KEY64170.1 - 0.0065 16.2 0.3 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEY64170.1 - 0.0074 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEY64170.1 - 0.0085 16.3 0.3 0.015 15.6 0.3 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEY64170.1 - 0.012 15.7 0.2 0.023 14.8 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KEY64170.1 - 0.012 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KEY64170.1 - 0.025 15.0 0.0 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KEY64170.1 - 0.029 14.0 0.2 0.057 13.0 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KEY64170.1 - 0.035 14.6 0.1 0.081 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY64170.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 KEY64170.1 - 0.053 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KEY64170.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEY64170.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KEY64170.1 - 0.11 11.1 0.1 1 7.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEY64170.1 - 0.12 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEY64170.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 KEY64170.1 - 0.15 11.7 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 Cytidylate kinase NTPase_1 PF03266.15 KEY64170.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 KEY64170.1 - 0.22 11.3 0.2 0.49 10.1 0.2 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein p450 PF00067.22 KEY64172.1 - 2.6e-63 214.4 0.0 3.3e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 KEY64173.1 - 8.2e-13 48.4 0.3 1.4e-12 47.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Med11 PF10280.9 KEY64173.1 - 0.028 14.9 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Mediator complex protein DivIC PF04977.15 KEY64173.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KEY64173.1 - 0.82 9.8 6.1 2 8.5 3.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KEY64173.1 - 7.4 6.7 9.6 22 5.2 3.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Zn_clus PF00172.18 KEY64174.1 - 7.5e-05 22.8 8.5 7.5e-05 22.8 8.5 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBC PF03792.13 KEY64174.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 PBC domain Abhydrolase_4 PF08386.10 KEY64175.1 - 7.3e-20 71.0 0.0 1.6e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY64175.1 - 2.3e-16 60.2 0.0 2.9e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_34 PF11312.8 KEY64176.1 - 3.3e-81 272.9 0.0 3.9e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF4865 PF16157.5 KEY64176.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) DIOX_N PF14226.6 KEY64177.1 - 4.9e-18 66.0 0.1 1.1e-17 64.9 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY64177.1 - 3.3e-15 56.4 0.0 1.1e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KEY64178.1 - 3.1e-06 27.2 10.3 5.8e-06 26.3 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KEY64178.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Amidohydro_1 PF01979.20 KEY64179.1 - 2.7e-62 211.1 1.2 3.4e-62 210.7 1.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY64179.1 - 2.8e-20 73.2 2.2 1.4e-15 57.7 0.9 2.8 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KEY64179.1 - 0.00016 21.2 0.4 0.0035 16.7 0.3 2.5 1 1 1 2 2 2 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 KEY64180.1 - 6.2e-48 163.4 28.9 2.2e-47 161.6 28.9 1.7 1 1 0 1 1 1 1 Permease family 4HB_MCP_1 PF12729.7 KEY64180.1 - 0.29 10.7 0.1 0.52 9.8 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Sugar_tr PF00083.24 KEY64181.1 - 1.3e-117 393.4 16.2 1.5e-117 393.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64181.1 - 1.1e-22 80.5 33.9 1.7e-12 47.0 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF711 PF05167.12 KEY64183.1 - 0.0051 15.8 0.0 0.0058 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) LIF_OSM PF01291.17 KEY64183.1 - 0.054 13.6 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 LIF / OSM family PEP-utilisers_N PF05524.13 KEY64185.1 - 0.017 15.3 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-CCHC_4 PF14392.6 KEY64185.1 - 0.093 12.5 5.7 1.3 8.8 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 KEY64185.1 - 0.098 12.4 1.8 0.17 11.6 1.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3716 PF12511.8 KEY64185.1 - 0.26 11.4 2.1 0.45 10.6 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) AATase PF07247.12 KEY64186.1 - 2.1e-15 56.3 0.0 1.3e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Alcohol acetyltransferase Zn_clus PF00172.18 KEY64187.1 - 1.3e-05 25.2 8.3 2.7e-05 24.2 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4449 PF14613.6 KEY64187.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) PSI PF01437.25 KEY64187.1 - 0.31 11.6 3.7 0.66 10.6 3.7 1.5 1 0 0 1 1 1 0 Plexin repeat Mito_carr PF00153.27 KEY64188.1 - 9.1e-43 144.1 2.8 8.2e-14 51.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_trans PF01144.23 KEY64190.1 - 4e-99 330.4 1.6 7e-59 198.8 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KEY64190.1 - 0.00043 18.8 0.0 0.00071 18.0 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 KEY64190.1 - 0.0065 16.4 1.8 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Sulfotransfer_4 PF17784.1 KEY64191.1 - 1.1e-47 162.6 0.0 1.3e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY64191.1 - 0.012 16.0 0.1 0.74 10.2 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family Methyltransf_16 PF10294.9 KEY64192.1 - 5.6e-18 65.3 0.1 1.8e-17 63.6 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase DUF604 PF04646.12 KEY64193.1 - 1.8e-09 37.4 0.2 1.7e-08 34.2 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KEY64193.1 - 5.4e-08 32.6 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Quaking_NLS PF16551.5 KEY64193.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking Glyco_hydro_61 PF03443.14 KEY64195.1 - 6.1e-53 179.8 0.0 7.3e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S10 PF00450.22 KEY64196.1 - 3.2e-78 264.0 0.6 1.2e-77 262.2 0.6 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase MDH PF02315.16 KEY64197.1 - 0.075 13.1 0.1 0.092 12.8 0.1 1.2 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit XhlA PF10779.9 KEY64197.1 - 0.15 12.3 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Ribonuclease_3 PF00636.26 KEY64198.1 - 1.2e-41 141.5 0.1 1.5e-19 70.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEY64198.1 - 2e-26 92.6 0.0 2.9e-11 43.6 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KEY64198.1 - 5.1e-20 71.4 0.1 1.3e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KEY64198.1 - 2.2e-16 60.2 0.0 6.2e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY64198.1 - 3.7e-14 52.9 0.0 7.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEY64198.1 - 2.3e-11 44.0 0.0 5.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEY64198.1 - 0.1 11.8 0.2 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DSPc PF00782.20 KEY64199.1 - 5.8e-10 39.1 0.3 4.4e-09 36.2 0.1 2.3 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KEY64199.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 1 1 2 2 2 0 Rit1 DUSP-like domain SUV3_C PF12513.8 KEY64200.1 - 1.6e-16 60.0 0.6 3.5e-16 58.9 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KEY64200.1 - 2.8e-08 34.1 0.0 7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KEY64200.1 - 3.2e-08 33.3 0.1 6.5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Synaptobrevin PF00957.21 KEY64201.1 - 2.4e-32 110.6 0.2 3.2e-32 110.2 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEY64201.1 - 1e-28 99.2 0.0 1.8e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.25 KEY64202.1 - 2.9e-14 53.0 0.0 1.3e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64202.1 - 2.1e-06 27.5 0.0 4.6e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64202.1 - 2.6e-05 24.2 0.0 8.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY64202.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY64202.1 - 0.005 16.3 1.0 0.012 15.0 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase CP12 PF02672.15 KEY64202.1 - 1.1 10.1 8.5 2.4 9.0 8.5 1.6 1 0 0 1 1 1 0 CP12 domain DUF2235 PF09994.9 KEY64203.1 - 2.4e-101 338.9 1.6 3.4e-101 338.4 1.6 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Velvet PF11754.8 KEY64203.1 - 0.079 12.9 2.3 0.15 12.0 2.3 1.4 1 0 0 1 1 1 0 Velvet factor ECH_1 PF00378.20 KEY64204.1 - 7.2e-49 166.3 0.0 9.6e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY64204.1 - 3.1e-22 79.5 0.0 4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PWI PF01480.17 KEY64206.1 - 1.6e-13 50.7 0.2 3.3e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 PWI domain GerPC PF10737.9 KEY64206.1 - 0.36 10.9 4.2 8.5 6.4 0.2 2.8 3 0 0 3 3 3 0 Spore germination protein GerPC Ribosomal_S21 PF01165.20 KEY64207.1 - 2.8e-09 36.5 3.2 4.5e-09 35.9 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 HAUS6_N PF14661.6 KEY64208.1 - 2.2e-56 191.0 0.3 2.2e-56 191.0 0.3 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HET PF06985.11 KEY64209.1 - 1.2e-27 97.1 0.7 1.9e-27 96.4 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Coatomer_WDAD PF04053.14 KEY64210.1 - 4.3e-174 579.7 0.0 9.6e-174 578.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region Sulfatase PF00884.23 KEY64210.1 - 3.4e-62 210.6 0.2 6.7e-62 209.6 0.2 1.5 1 0 0 1 1 1 1 Sulfatase WD40 PF00400.32 KEY64210.1 - 2.7e-36 123.0 9.2 6e-06 26.9 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64210.1 - 3e-05 24.2 0.1 5.2 7.4 0.0 5.5 4 1 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY64210.1 - 0.0013 17.4 1.8 0.096 11.3 0.0 3.4 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Phosphoesterase PF04185.14 KEY64210.1 - 0.0045 16.2 0.1 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoesterase family C2 PF00168.30 KEY64211.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain PGI PF00342.19 KEY64212.1 - 1e-226 753.3 0.2 1.1e-226 753.1 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mannitol_dh_C PF08125.13 KEY64213.1 - 4.4e-40 137.7 0.1 6.9e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KEY64213.1 - 4.6e-21 75.6 0.2 7.1e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KEY64213.1 - 0.0025 17.4 0.1 0.0054 16.3 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3842 PF12953.7 KEY64213.1 - 0.043 14.2 0.3 0.082 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) F420_oxidored PF03807.17 KEY64213.1 - 0.044 14.3 0.3 0.65 10.6 0.3 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEY64213.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4440 PF14534.6 KEY64214.1 - 4.2e-11 43.2 0.0 5.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4419 PF14388.6 KEY64215.1 - 1e-95 320.6 0.0 1.3e-95 320.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RACo_linker PF17650.1 KEY64215.1 - 0.21 11.5 0.1 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 RACo linker region Polysacc_deac_1 PF01522.21 KEY64217.1 - 4.2e-30 104.2 0.1 7.5e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KEY64217.1 - 1.7e-12 47.6 42.8 6.1e-07 29.8 19.5 2.7 2 1 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 KEY64217.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) MFS_1 PF07690.16 KEY64219.1 - 1.4e-16 60.4 51.7 1.3e-15 57.2 49.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Ank_3 PF13606.6 KEY64220.1 - 0.002 18.5 0.1 13 6.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KEY64220.1 - 0.0021 18.6 0.2 0.71 10.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) SHOCT PF09851.9 KEY64220.1 - 0.19 11.5 0.7 0.4 10.5 0.3 1.8 2 0 0 2 2 2 0 Short C-terminal domain Epimerase PF01370.21 KEY64222.1 - 1.7e-15 57.1 0.0 5.9e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY64222.1 - 4.2e-12 45.7 0.0 6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY64222.1 - 1.7e-07 30.7 0.0 0.00029 20.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEY64222.1 - 4e-07 30.1 0.0 6.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY64222.1 - 6.9e-06 25.8 1.3 1.3e-05 24.8 1.3 1.6 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY64222.1 - 2.4e-05 23.9 0.1 7.4e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KEY64222.1 - 2.8e-05 23.6 0.1 0.0021 17.5 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY64222.1 - 0.0018 18.2 0.5 0.006 16.5 0.5 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY64222.1 - 0.0034 16.6 0.1 0.0054 15.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ImcF-related_N PF14331.6 KEY64223.1 - 0.0056 16.1 0.1 0.0065 15.9 0.1 1.1 1 0 0 1 1 1 1 ImcF-related N-terminal domain PRKG1_interact PF15898.5 KEY64223.1 - 0.0071 17.2 0.5 0.011 16.6 0.5 1.3 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain G_glu_transpept PF01019.21 KEY64224.1 - 1.4e-163 545.4 0.1 1.6e-163 545.2 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF4942 PF13708.6 KEY64225.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) Pectate_lyase PF03211.13 KEY64226.1 - 9.7e-62 208.1 1.1 1.3e-61 207.7 1.1 1.1 1 0 0 1 1 1 1 Pectate lyase DMAP1_like PF17024.5 KEY64226.1 - 0.018 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative DMAP1-like Zn_clus PF00172.18 KEY64227.1 - 5.3e-07 29.6 11.0 9.5e-07 28.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KEY64228.1 - 1.7e-29 103.0 0.0 3e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64228.1 - 3.4e-20 72.4 0.0 5.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 KEY64228.1 - 2.1e-16 60.6 0.0 6.1e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KEY64229.1 - 2.9e-15 56.4 0.0 2.8e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Acyl_transf_3 PF01757.22 KEY64230.1 - 1.8e-34 119.3 17.0 3.1e-34 118.6 17.0 1.4 1 0 0 1 1 1 1 Acyltransferase family CReP_N PF10472.9 KEY64230.1 - 0.0018 17.2 0.5 0.0027 16.7 0.5 1.1 1 0 0 1 1 1 1 eIF2-alpha phosphatase phosphorylation constitutive repressor DUF1768 PF08719.11 KEY64231.1 - 2.2e-53 180.8 0.1 2.7e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Methyltr_RsmB-F PF01189.17 KEY64232.1 - 3.9e-18 65.8 0.0 2.3e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1996 PF09362.10 KEY64233.1 - 1.5e-66 224.8 0.2 2e-66 224.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sigma70_ner PF04546.13 KEY64233.1 - 0.15 11.9 1.9 0.3 11.0 1.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Metallophos PF00149.28 KEY64234.1 - 5.9e-17 62.9 0.2 7.9e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY64234.1 - 0.022 15.0 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Velvet PF11754.8 KEY64235.1 - 7.5e-49 166.9 9.5 1.6e-29 103.6 0.1 3.3 2 2 1 3 3 3 3 Velvet factor Cellulase PF00150.18 KEY64236.1 - 8.4e-21 74.6 0.2 1.2e-20 74.2 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KEY64236.1 - 6.7e-12 45.2 8.0 1.6e-11 44.0 8.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KEY64236.1 - 0.0021 17.2 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KEY64236.1 - 0.024 14.0 0.0 0.062 12.6 0.1 1.6 2 0 0 2 2 2 0 Beta-galactosidase Transp_inhibit PF18791.1 KEY64236.1 - 0.34 10.4 1.2 0.6 9.6 0.4 1.8 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain MCRS_N PF13325.6 KEY64237.1 - 0.022 14.8 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein CbbQ_C PF08406.10 KEY64237.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal NGP1NT PF08153.12 KEY64238.1 - 2.1e-50 170.2 0.7 3.3e-50 169.6 0.7 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KEY64238.1 - 4.9e-17 62.0 0.0 9.5e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEY64238.1 - 7.8e-06 26.0 0.5 0.031 14.3 0.2 3.5 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KEY64238.1 - 9.4e-06 25.2 0.1 6.3e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEY64238.1 - 0.00018 21.4 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KEY64238.1 - 0.00084 18.8 0.0 0.79 9.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY64238.1 - 0.0033 17.0 0.1 0.39 10.2 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KEY64238.1 - 0.018 15.3 0.1 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KEY64238.1 - 0.022 14.1 0.1 0.086 12.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family ABC2_membrane PF01061.24 KEY64240.1 - 7.5e-38 130.1 18.7 7.5e-38 130.1 18.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KEY64240.1 - 8.3e-25 87.9 0.1 2.2e-24 86.5 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KEY64240.1 - 2.8e-05 24.1 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KEY64240.1 - 0.00016 20.9 11.6 0.00016 20.9 11.6 2.4 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KEY64240.1 - 0.0054 16.4 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY64240.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KEY64240.1 - 0.029 13.9 0.1 0.072 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEY64240.1 - 0.035 14.6 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEY64240.1 - 0.043 13.3 0.0 0.3 10.5 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEY64240.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KEY64240.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF5325 PF17259.2 KEY64240.1 - 0.1 12.5 3.7 0.54 10.2 3.7 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) AAA_22 PF13401.6 KEY64240.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ctr PF04145.15 KEY64240.1 - 0.17 12.5 0.7 0.46 11.1 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Glyco_transf_90 PF05686.12 KEY64242.1 - 4.4e-06 25.9 0.2 0.008 15.1 0.1 3.2 3 1 0 3 3 3 2 Glycosyl transferase family 90 DHHC PF01529.20 KEY64243.1 - 3.2e-30 105.0 5.5 6.2e-30 104.0 5.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Myosin_head PF00063.21 KEY64244.1 - 1.7e-238 793.3 3.9 2e-238 793.0 3.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KEY64244.1 - 4.2e-50 170.0 0.0 8.5e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KEY64244.1 - 6.7e-12 44.8 0.1 1.3e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY64244.1 - 8.7e-09 35.1 0.1 2.8e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KEY64244.1 - 1.4e-05 24.7 0.0 4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.27 KEY64244.1 - 0.0049 16.6 10.0 0.17 11.7 2.4 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KEY64244.1 - 0.031 13.8 0.7 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KEY64244.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain SH3_3 PF08239.11 KEY64244.1 - 0.083 13.2 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_16 PF13191.6 KEY64244.1 - 0.1 13.0 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEY64244.1 - 0.11 12.4 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SepF PF04472.12 KEY64244.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 Cell division protein SepF DUF4913 PF16259.5 KEY64244.1 - 0.18 11.9 1.5 0.53 10.4 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) RPEL PF02755.15 KEY64245.1 - 1.5e-20 72.2 6.0 3.4e-10 39.3 0.4 2.5 2 0 0 2 2 2 2 RPEL repeat FKBP_C PF00254.28 KEY64247.1 - 1.8e-35 121.1 0.0 2.8e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MT0933_antitox PF14013.6 KEY64247.1 - 0.0014 18.9 2.6 0.0032 17.7 2.6 1.6 1 0 0 1 1 1 1 MT0933-like antitoxin protein DUF745 PF05335.13 KEY64247.1 - 0.055 13.2 9.8 0.084 12.6 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) YtxH PF12732.7 KEY64247.1 - 0.23 12.0 4.2 0.49 11.0 4.2 1.5 1 0 0 1 1 1 0 YtxH-like protein TrkH PF02386.16 KEY64248.1 - 1.3e-98 330.7 10.2 6.7e-97 325.0 2.9 2.1 2 0 0 2 2 2 2 Cation transport protein IMS PF00817.20 KEY64249.1 - 3.1e-43 147.3 0.3 8.4e-43 145.9 0.3 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEY64249.1 - 3.6e-15 56.7 0.0 9.8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KEY64249.1 - 0.0035 17.6 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Arg_repressor PF01316.21 KEY64249.1 - 0.33 10.7 1.9 1.4 8.7 0.7 2.5 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain zf-RanBP PF00641.18 KEY64249.1 - 2.1 7.7 4.5 1.5 8.2 0.7 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others EphA2_TM PF14575.6 KEY64251.1 - 0.0063 17.4 0.9 0.017 16.0 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KEY64251.1 - 0.014 15.4 0.1 0.014 15.4 0.1 2.1 1 1 2 3 3 3 0 Protocadherin Insulin_TMD PF17870.1 KEY64251.1 - 0.039 14.0 0.5 0.066 13.3 0.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4834 PF16118.5 KEY64251.1 - 0.041 14.8 0.1 0.041 14.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5082 PF16888.5 KEY64251.1 - 0.066 13.5 0.4 0.066 13.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Zip PF02535.22 KEY64251.1 - 0.082 12.1 0.1 0.15 11.2 0.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KEY64251.1 - 0.39 8.9 7.6 0.52 8.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein UL42 PF17638.2 KEY64251.1 - 0.66 10.0 2.4 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 HCMV UL42 DUF2561 PF10812.8 KEY64251.1 - 1 9.3 0.0 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) Kei1 PF08552.11 KEY64251.1 - 1.2 9.0 3.5 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1690 PF07956.11 KEY64251.1 - 2.5 8.5 7.2 4.3 7.8 7.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) CcmD PF04995.14 KEY64251.1 - 6.7 6.9 11.3 0.1 12.7 3.3 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) FUSC PF04632.12 KEY64251.1 - 6.8 5.1 11.4 19 3.6 7.5 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family FMN_red PF03358.15 KEY64252.1 - 1.8e-07 31.0 0.0 2.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEY64252.1 - 2.9e-05 23.9 0.0 3.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KEY64252.1 - 0.00076 19.7 0.0 0.016 15.4 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KEY64252.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain F-box PF00646.33 KEY64254.1 - 0.0034 17.2 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KEY64254.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KEY64254.1 - 0.049 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 F-box Raf1_N PF18578.1 KEY64254.1 - 0.14 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain PRANC PF09372.10 KEY64254.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain DUF3486 PF11985.8 KEY64254.1 - 0.16 12.4 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) SET PF00856.28 KEY64255.1 - 2.9e-07 31.0 0.1 8.2e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 SET domain WD40 PF00400.32 KEY64256.1 - 1.2e-33 114.5 10.0 1.3e-06 29.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64256.1 - 1.4e-13 50.9 0.0 4.5e-06 26.9 0.0 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cornichon PF03311.14 KEY64257.1 - 3.2e-49 166.3 12.3 3.6e-49 166.1 12.3 1.0 1 0 0 1 1 1 1 Cornichon protein Cytochrom_B562 PF07361.11 KEY64258.1 - 0.04 14.6 0.1 0.62 10.8 0.0 2.7 2 0 0 2 2 2 0 Cytochrome b562 Prenyltransf PF01255.19 KEY64258.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RRM_1 PF00076.22 KEY64259.1 - 1.5e-83 274.6 7.7 3.8e-22 77.9 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KEY64259.1 - 6.3e-29 100.0 1.0 3e-28 97.8 1.0 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KEY64259.1 - 1.6e-08 34.2 0.0 0.047 13.3 0.0 4.9 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY64259.1 - 5.1e-07 29.5 0.0 0.00056 19.7 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KEY64259.1 - 4.3e-06 26.8 1.4 0.4 10.8 0.0 5.2 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KEY64259.1 - 7.4e-05 22.7 0.8 8.8 6.4 0.1 4.5 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KEY64259.1 - 0.00062 20.2 8.9 0.058 13.9 0.6 3.5 3 1 0 3 3 3 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KEY64259.1 - 0.038 14.1 0.0 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.11 KEY64259.1 - 0.18 11.5 3.2 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain DHHA1 PF02272.19 KEY64259.1 - 0.37 11.2 7.6 0.86 10.0 0.1 3.5 4 0 0 4 4 4 0 DHHA1 domain DUF3408 PF11888.8 KEY64259.1 - 0.93 9.6 7.4 0.12 12.5 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) HECT PF00632.25 KEY64260.1 - 4.9e-78 262.7 0.0 7.6e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KEY64260.1 - 0.00021 20.8 2.7 0.00058 19.4 2.7 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cwf_Cwc_15 PF04889.12 KEY64260.1 - 2.9 7.5 9.2 0.072 12.8 2.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_92 PF07971.12 KEY64261.1 - 3.5e-146 487.8 0.0 4.3e-146 487.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KEY64261.1 - 3.5e-61 207.1 0.6 6.5e-61 206.3 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GDI PF00996.18 KEY64261.1 - 0.24 9.9 0.0 0.37 9.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Mpp10 PF04006.12 KEY64262.1 - 4.5e-107 359.0 41.6 1.4e-106 357.4 41.6 1.7 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 KEY64262.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KEY64262.1 - 8.2e-06 26.5 0.0 4.9e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY64262.1 - 0.00012 22.8 0.0 0.00043 21.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KEY64262.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KEY64262.1 - 0.0038 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY64262.1 - 0.0053 16.3 0.0 0.079 12.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 KEY64262.1 - 0.054 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PHC2_SAM_assoc PF16616.5 KEY64262.1 - 8.7 7.2 7.9 2.1 9.2 0.3 3.1 3 0 0 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 SHNi-TPR PF10516.9 KEY64263.1 - 3e-09 36.2 0.1 1e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 SHNi-TPR TPR_16 PF13432.6 KEY64263.1 - 0.0033 18.0 0.3 0.05 14.2 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY64263.1 - 0.015 15.4 4.5 1.1 9.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEY64263.1 - 0.055 13.8 1.2 1.7 9.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEY64263.1 - 0.097 12.7 1.9 0.15 12.1 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro-NT_NN PF07421.11 KEY64263.1 - 4.9 7.4 6.9 0.85 9.9 2.5 1.9 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor Glyoxalase PF00903.25 KEY64264.1 - 0.0043 17.2 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEY64264.1 - 0.012 16.4 0.0 0.025 15.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain DHquinase_I PF01487.15 KEY64265.1 - 6e-46 157.5 0.0 9.1e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase CBM46 PF18448.1 KEY64265.1 - 0.13 12.6 0.1 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Carbohydrate binding domain Cyclin PF08613.11 KEY64266.1 - 1.2e-10 41.9 0.0 1.9e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEY64266.1 - 0.00033 20.4 0.1 0.00055 19.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.7 KEY64267.1 - 1.4e-74 246.7 18.7 2.6e-14 53.6 0.1 15.8 9 4 6 16 16 16 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY64267.1 - 1.1e-63 210.8 36.7 5.2e-07 30.1 0.0 20.3 18 2 2 20 20 20 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY64267.1 - 2.5e-58 193.4 39.6 3.9e-05 23.9 0.0 21.3 19 2 2 21 21 21 11 Ankyrin repeats (many copies) Ank PF00023.30 KEY64267.1 - 1.9e-44 148.2 41.5 0.00017 21.9 0.0 25.2 26 2 0 26 26 26 9 Ankyrin repeat Ank_3 PF13606.6 KEY64267.1 - 2.1e-44 144.4 29.1 0.00059 20.1 0.0 24.9 30 0 0 30 30 28 9 Ankyrin repeat NACHT PF05729.12 KEY64267.1 - 1.5e-08 34.8 0.1 5.8e-08 32.8 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY64267.1 - 2.3e-06 28.1 1.1 1.1e-05 25.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY64267.1 - 0.018 15.3 0.3 0.25 11.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain ERAP1_C PF11838.8 KEY64267.1 - 0.021 14.4 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain DUF2075 PF09848.9 KEY64267.1 - 0.085 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KEY64267.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2461 PF09365.10 KEY64269.1 - 0.02 14.8 5.8 0.039 13.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) TFIIA PF03153.13 KEY64269.1 - 0.55 10.2 18.0 1.1 9.2 4.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 KEY64269.1 - 2.3 6.4 4.9 3.3 5.9 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein phiKZ_IP PF12699.7 KEY64269.1 - 5.7 6.0 6.6 8.7 5.4 6.6 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Bac_export_1 PF01311.20 KEY64270.1 - 0.02 14.4 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial export proteins, family 1 MNHE PF01899.16 KEY64270.1 - 0.054 13.2 0.2 0.071 12.9 0.2 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF2939 PF11159.8 KEY64270.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PsbX PF06596.11 KEY64270.1 - 0.32 11.0 6.8 28 4.8 6.8 2.3 1 1 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) LapA_dom PF06305.11 KEY64270.1 - 0.6 10.0 2.8 1.1 9.2 2.8 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SAM_2 PF07647.17 KEY64271.1 - 1.7e-16 60.1 0.0 3.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEY64271.1 - 1.2e-14 54.4 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KEY64271.1 - 1.4e-11 44.8 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KEY64271.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.21 KEY64272.1 - 2.6e-58 198.0 0.0 3.4e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEY64272.1 - 0.022 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEY64272.1 - 0.13 11.5 0.0 0.28 10.5 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 KEY64273.1 - 5.9e-47 160.2 0.0 8.5e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY64273.1 - 1.4e-05 26.0 0.1 7.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEY64273.1 - 0.00034 20.5 1.8 0.00078 19.3 0.2 2.4 2 1 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 KEY64274.1 - 1.5e-37 126.9 19.1 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64274.1 - 3.7e-14 52.8 0.0 0.00035 20.8 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY64274.1 - 0.00013 21.0 0.0 0.8 8.6 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEY64274.1 - 0.00016 21.7 0.0 0.12 12.3 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEY64274.1 - 0.00086 18.7 0.0 0.039 13.3 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Phosducin PF02114.16 KEY64275.1 - 4.5e-11 42.2 0.1 3.7e-10 39.2 0.1 2.1 1 1 0 1 1 1 1 Phosducin GATA PF00320.27 KEY64276.1 - 2.8e-15 55.6 3.5 4.7e-15 54.9 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger MIF4G PF02854.19 KEY64277.1 - 3.1e-52 177.3 0.0 6.4e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KEY64277.1 - 4e-22 78.2 3.5 5.6e-22 77.7 0.8 2.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF4148 PF13663.6 KEY64277.1 - 0.015 15.4 1.5 0.26 11.5 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DNA_pol_B PF00136.21 KEY64278.1 - 1.3e-116 390.1 0.2 5.4e-116 388.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KEY64278.1 - 5.3e-68 228.4 0.1 9.7e-68 227.6 0.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KEY64278.1 - 2.5e-41 141.9 0.0 4.8e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KEY64278.1 - 3.1e-24 84.8 8.4 3.1e-24 84.8 8.4 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KEY64278.1 - 0.007 15.3 0.1 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral TF_Zn_Ribbon PF08271.12 KEY64278.1 - 0.051 13.1 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding PPR_2 PF13041.6 KEY64279.1 - 5.9e-23 80.8 4.5 1.2e-16 60.6 0.3 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KEY64279.1 - 1.8e-10 40.8 0.5 8.4e-05 22.6 0.1 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KEY64279.1 - 9.2e-09 35.0 2.3 3.7e-08 33.0 0.2 2.6 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEY64279.1 - 4.6e-07 29.7 1.0 0.017 15.4 0.2 4.2 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 KEY64279.1 - 1.4e-06 27.9 0.6 2.9 7.7 0.2 4.9 5 0 0 5 5 5 2 PPR repeat ATP13 PF12921.7 KEY64279.1 - 0.0014 18.4 0.8 0.077 12.9 0.0 3.5 3 1 1 4 4 4 1 Mitochondrial ATPase expression SRP_TPR_like PF17004.5 KEY64279.1 - 0.0039 17.2 0.8 0.0081 16.2 0.8 1.5 1 0 0 1 1 1 1 Putative TPR-like repeat Drf_FH3 PF06367.16 KEY64279.1 - 0.099 12.2 1.8 5.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Diaphanous FH3 Domain TAP_C PF03943.13 KEY64279.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Btz PF09405.10 KEY64280.1 - 0.0028 17.9 0.1 0.0049 17.1 0.1 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 KEY64281.1 - 1.5e-50 172.1 0.1 6e-50 170.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64281.1 - 2.2e-23 82.9 0.3 6.1e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEY64281.1 - 0.00016 21.7 1.1 0.00031 20.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEY64281.1 - 0.0028 17.3 0.2 0.008 15.8 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KEY64281.1 - 0.36 10.4 1.7 0.38 10.3 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 KEY64282.1 - 9.4e-60 198.4 0.0 3.2e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY64282.1 - 2.1e-09 37.1 0.0 0.02 14.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KEY64282.1 - 9.3e-09 34.9 0.0 1.8e-05 24.3 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY64282.1 - 4.8e-06 26.5 0.1 0.18 11.8 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KEY64282.1 - 0.00011 22.1 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 KEY64282.1 - 0.00053 20.1 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 KEY64282.1 - 0.0012 18.9 0.2 0.57 10.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KEY64282.1 - 0.19 11.8 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Med2 PF11214.8 KEY64283.1 - 0.0036 17.4 0.1 0.0081 16.3 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 2 Cellulase PF00150.18 KEY64284.1 - 1.7e-18 67.1 0.1 3.3e-18 66.1 0.1 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) B12-binding PF02310.19 KEY64284.1 - 0.0036 17.3 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain PH PF00169.29 KEY64285.1 - 2.9e-25 88.8 0.9 4.5e-14 52.8 0.2 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KEY64285.1 - 6.4e-10 39.4 5.2 0.00018 21.9 0.6 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KEY64285.1 - 4.1e-08 33.6 1.6 0.00041 20.7 0.9 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KEY64285.1 - 0.00016 21.8 0.2 0.00031 21.0 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KEY64285.1 - 0.0028 17.7 0.3 0.016 15.3 0.2 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KEY64285.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 KEY64286.1 - 5.3e-12 46.2 0.1 7.4e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY64286.1 - 0.00032 20.4 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEY64286.1 - 0.0062 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KEY64286.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CTU2 PF10288.9 KEY64287.1 - 1e-10 41.8 0.1 6.2e-09 36.1 0.0 2.5 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF4166 PF13761.6 KEY64287.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) Mito_carr PF00153.27 KEY64288.1 - 9.5e-56 185.7 3.4 6.6e-18 64.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Adeno_E3A PF05248.12 KEY64288.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3A WD40 PF00400.32 KEY64289.1 - 2.2e-19 69.4 1.5 2.5e-08 34.4 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64289.1 - 6.5e-08 32.8 0.0 0.098 13.0 0.0 4.7 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KEY64289.1 - 0.016 13.9 0.1 1.1 8.0 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like SRP9-21 PF05486.12 KEY64290.1 - 1.8e-34 118.0 0.0 2.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) LCE6A PF15858.5 KEY64290.1 - 0.76 10.6 3.5 0.22 12.3 0.5 1.7 2 0 0 2 2 2 0 Late cornified envelope protein 6A family Ribonuc_red_sm PF00268.21 KEY64291.1 - 3.1e-122 407.4 1.6 4e-122 407.0 1.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.6 KEY64292.1 - 1.5e-34 118.4 0.7 2e-34 118.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 KEY64292.1 - 0.057 13.5 0.2 0.095 12.7 0.2 1.3 1 0 0 1 1 1 0 Staphylococcal AgrD protein Stm1_N PF09598.10 KEY64292.1 - 3.7 8.5 8.4 1.1 10.2 2.3 2.2 2 0 0 2 2 2 0 Stm1 DCP2 PF05026.13 KEY64293.1 - 3.2e-31 107.5 0.9 7.1e-31 106.4 0.9 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KEY64293.1 - 4.3e-16 59.2 0.0 8.2e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain BC10 PF06726.12 KEY64295.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Pkinase PF00069.25 KEY64296.1 - 4.4e-59 200.0 0.0 5.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64296.1 - 4.1e-27 95.1 0.0 5.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY64296.1 - 0.0049 16.8 0.0 0.0049 16.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY64296.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KEY64296.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEY64296.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_28 PF02636.17 KEY64297.1 - 3.6e-84 282.5 0.0 4.4e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.13 KEY64298.1 - 1.3e-69 234.7 15.3 1.6e-69 234.4 15.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1980 PF09323.10 KEY64298.1 - 0.18 11.7 0.5 0.67 9.8 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SurA_N_3 PF13624.6 KEY64298.1 - 0.51 10.1 1.9 6.3 6.6 0.1 2.7 2 1 1 3 3 3 0 SurA N-terminal domain Tmemb_55A PF09788.9 KEY64298.1 - 4.3 6.3 4.2 1.2 8.2 1.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 55A Pro_isomerase PF00160.21 KEY64299.1 - 3.1e-49 167.3 0.0 6.8e-49 166.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KEY64299.1 - 2.1e-05 24.6 0.1 0.00022 21.3 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KEY64299.1 - 0.00053 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Zn_clus PF00172.18 KEY64300.1 - 9.2e-08 32.1 11.4 2.2e-07 30.9 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3142 PF11340.8 KEY64300.1 - 0.098 12.5 0.2 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) Glyco_hydro_64 PF16483.5 KEY64301.1 - 2e-130 435.4 0.0 2.6e-130 435.0 0.0 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Glyco_hydro_16 PF00722.21 KEY64301.1 - 2.7e-10 40.0 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KEY64302.1 - 2.8e-15 56.1 2.6 4.4e-15 55.4 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KEY64302.1 - 4.8e-08 33.1 12.2 1.1e-05 25.6 5.8 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KEY64302.1 - 0.00073 19.9 14.6 0.04 14.4 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KEY64302.1 - 0.051 14.3 1.0 1.8 9.3 0.5 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KEY64302.1 - 0.26 12.2 19.5 0.27 12.2 4.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY64302.1 - 0.55 10.6 3.7 1.4 9.3 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KEY64302.1 - 1.5 9.0 4.1 4.1 7.6 4.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain RasGEF PF00617.19 KEY64303.1 - 3.4e-60 203.3 0.2 6.3e-60 202.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEY64303.1 - 3.2e-30 104.5 0.8 8.8e-30 103.0 0.8 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KEY64303.1 - 1.5e-15 56.5 0.1 3.3e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY64303.1 - 5.5e-14 51.8 0.1 1.5e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY64303.1 - 1.7e-13 50.0 0.1 1e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KEY64303.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF1944 PF09175.10 KEY64303.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) AflR PF08493.10 KEY64304.1 - 0.28 10.6 4.5 0.4 10.1 4.5 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Lipase_GDSL_2 PF13472.6 KEY64305.1 - 2e-09 38.1 0.1 5.8e-08 33.3 0.0 2.3 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY64305.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase EMC3_TMCO1 PF01956.16 KEY64306.1 - 0.12 12.1 1.7 0.13 12.0 1.7 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fungal_trans_2 PF11951.8 KEY64308.1 - 7.3e-08 31.6 0.0 2.6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tospo_nucleocap PF01533.16 KEY64308.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein SCA7 PF08313.12 KEY64309.1 - 1.1e-31 108.5 0.1 3.9e-31 106.8 0.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 KEY64309.1 - 0.36 9.1 13.8 0.48 8.7 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 KEY64310.1 - 2e-47 159.1 0.7 5.6e-16 58.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-NOSIP PF15906.5 KEY64311.1 - 2.3e-08 34.0 0.0 9.4e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KEY64311.1 - 3.1e-07 30.3 9.2 1.4e-05 25.1 3.0 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KEY64311.1 - 3e-05 23.9 4.7 3e-05 23.9 4.7 3.2 2 2 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEY64311.1 - 3.6e-05 24.0 16.5 0.00061 20.1 5.8 3.0 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KEY64311.1 - 6.3e-05 22.7 2.3 6.3e-05 22.7 2.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY64311.1 - 0.00012 21.8 1.2 0.00012 21.8 1.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KEY64311.1 - 0.00035 20.0 1.5 0.00035 20.0 1.5 2.6 2 1 1 3 3 3 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 KEY64311.1 - 0.0014 18.4 22.7 0.15 11.9 10.9 3.7 2 1 1 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY64311.1 - 0.0059 16.7 13.1 0.11 12.6 6.1 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.21 KEY64311.1 - 0.0073 16.4 7.3 0.014 15.5 1.6 2.7 2 0 0 2 2 2 1 FYVE zinc finger YwqJ-deaminase PF14431.6 KEY64311.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 YwqJ-like deaminase Acyltransferase PF01553.21 KEY64312.1 - 1.9e-11 43.7 0.0 2.2e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KEY64313.1 - 2.3e-77 259.9 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64313.1 - 1.9e-38 132.2 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY64313.1 - 0.0016 17.5 0.0 0.014 14.4 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY64313.1 - 0.072 12.4 1.1 0.081 12.3 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY64313.1 - 0.078 12.9 1.7 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Septin PF00735.18 KEY64314.1 - 3.3e-08 33.2 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Septin AhpC-TSA_2 PF13911.6 KEY64315.1 - 3.7e-09 36.7 0.0 5.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KEY64315.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Tubulin_3 PF14881.6 KEY64316.1 - 5.3e-76 254.3 0.0 2.9e-75 251.9 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 KEY64316.1 - 3.8e-39 133.6 0.2 1.1e-38 132.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KEY64316.1 - 1.8e-06 28.3 0.0 0.0048 17.1 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Aida_C2 PF14186.6 KEY64316.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal adhesion PAP_central PF04928.17 KEY64317.1 - 6.8e-111 369.2 0.0 8.7e-111 368.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KEY64317.1 - 2.2e-63 212.9 0.2 4.2e-63 212.0 0.2 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KEY64317.1 - 8.7e-10 38.8 0.0 2.6e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KEY64317.1 - 0.024 14.4 0.1 0.073 12.8 0.1 1.8 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Ribosomal_S21 PF01165.20 KEY64317.1 - 0.068 12.9 0.2 0.23 11.2 0.2 1.9 1 0 0 1 1 1 0 Ribosomal protein S21 Peptidase_S49 PF01343.18 KEY64317.1 - 0.078 12.9 0.4 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 DUF2423 PF10338.9 KEY64318.1 - 5e-19 68.3 6.2 5e-19 68.3 6.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Forkhead PF00250.18 KEY64319.1 - 3.4e-35 120.2 0.4 7.5e-35 119.1 0.4 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KEY64319.1 - 2e-11 44.1 0.1 9.9e-11 41.8 0.0 2.1 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KEY64319.1 - 7.3e-05 23.0 0.0 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KEY64319.1 - 0.05 13.8 0.0 0.87 9.9 0.0 2.3 1 1 0 1 1 1 0 FHA domain Linker_histone PF00538.19 KEY64319.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CLU PF13236.6 KEY64320.1 - 8e-77 258.0 0.0 1.3e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KEY64320.1 - 6.7e-55 185.8 0.0 1.6e-54 184.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KEY64320.1 - 9.4e-24 83.5 12.5 2.8e-12 46.7 0.2 4.3 3 1 3 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 KEY64320.1 - 1.6e-22 79.6 0.0 3.8e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KEY64320.1 - 8.1e-20 70.0 0.5 1.6e-05 24.6 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY64320.1 - 2.6e-07 30.3 3.2 0.012 15.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AF-4 PF05110.13 KEY64320.1 - 0.00069 17.9 12.2 0.0014 16.9 12.2 1.4 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TPR_2 PF07719.17 KEY64320.1 - 0.0029 17.6 2.5 4.9 7.5 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF727 PF05303.12 KEY64320.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.6 KEY64320.1 - 0.056 13.9 1.2 31 5.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY64320.1 - 0.17 12.0 0.9 1.6e+02 2.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1754 PF08555.10 KEY64320.1 - 0.56 11.0 12.9 0.55 11.1 7.4 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RP-C_C PF11800.8 KEY64320.1 - 1 9.4 5.3 9.6 6.2 3.0 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region SpoIIIAH PF12685.7 KEY64320.1 - 1.6 8.5 11.8 1.1 9.1 4.8 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein Hep_59 PF07052.11 KEY64320.1 - 1.7 9.5 10.6 0.14 12.9 4.7 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 SEEEED PF14797.6 KEY64320.1 - 2.2 8.5 25.9 0.12 12.6 17.4 2.5 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex RNA_pol_Rpc4 PF05132.14 KEY64320.1 - 4.3 7.8 7.0 15 6.0 3.4 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ferric_reduct PF01794.19 KEY64322.1 - 1.6e-21 76.7 10.0 3.5e-21 75.6 10.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY64322.1 - 7.9e-18 65.1 0.0 4.1e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY64322.1 - 1.6e-15 57.2 0.0 2e-13 50.4 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF4153 PF13687.6 KEY64322.1 - 0.2 11.2 6.0 0.46 10.1 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) DUF4405 PF14358.6 KEY64322.1 - 0.44 11.1 13.8 0.17 12.4 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF5337 PF17272.2 KEY64322.1 - 6.3 6.7 7.4 22 4.9 0.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5337) EamA PF00892.20 KEY64323.1 - 1.4e-08 35.0 26.0 4.3e-05 23.7 2.9 2.9 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KEY64323.1 - 6.2e-08 32.2 0.7 1e-07 31.4 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KEY64323.1 - 0.00084 18.8 0.1 0.00084 18.8 0.1 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 KEY64323.1 - 0.015 14.5 7.0 0.025 13.8 6.2 1.7 2 1 0 2 2 2 0 UAA transporter family DUF423 PF04241.15 KEY64323.1 - 0.037 14.2 0.4 3.9 7.7 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) CRT-like PF08627.10 KEY64323.1 - 0.046 12.7 10.2 0.03 13.3 4.7 2.7 2 1 1 3 3 3 0 CRT-like, chloroquine-resistance transporter-like Yippee-Mis18 PF03226.14 KEY64324.1 - 3.4e-16 59.3 0.3 3.9e-16 59.2 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 KEY64324.1 - 0.0028 17.5 0.8 2.4 8.1 0.1 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain RIG-I_C-RD PF11648.8 KEY64324.1 - 0.0098 16.1 0.9 0.013 15.7 0.9 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2985 PF11204.8 KEY64325.1 - 2.2e-39 133.5 1.5 4.2e-39 132.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SurA_N_3 PF13624.6 KEY64325.1 - 0.026 14.3 0.2 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain Sen15 PF09631.10 KEY64326.1 - 5.7e-28 97.2 0.0 7.7e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein ADH_N PF08240.12 KEY64327.1 - 2.2e-30 104.7 1.5 4e-30 103.9 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY64327.1 - 1.5e-15 57.3 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY64327.1 - 5.8e-06 25.9 0.0 9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEY64327.1 - 0.00084 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KEY64327.1 - 0.00095 20.2 0.0 0.0029 18.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEY64327.1 - 0.0097 15.8 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated PIEZO PF15917.5 KEY64328.1 - 0.1 12.1 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Piezo LysM PF01476.20 KEY64329.1 - 5.3e-15 55.2 0.0 4.2e-05 23.5 0.0 4.3 5 0 0 5 5 5 3 LysM domain CxC6 PF18721.1 KEY64329.1 - 0.016 15.4 0.4 0.064 13.5 0.1 2.2 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Glyco_hydro_18 PF00704.28 KEY64330.1 - 3.5e-73 247.1 0.7 5.1e-73 246.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY64330.1 - 2.8e-13 50.1 12.4 2.8e-13 50.1 12.4 5.2 5 1 0 5 5 5 1 Chitin recognition protein 2OG-FeII_Oxy_3 PF13640.6 KEY64332.1 - 3e-08 34.4 0.0 8.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_membrane PF00664.23 KEY64333.1 - 4.9e-90 301.9 24.9 7.7e-49 166.8 8.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY64333.1 - 3.9e-51 173.2 0.0 1.2e-30 106.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY64333.1 - 7.5e-10 38.6 3.2 0.011 15.2 0.1 4.3 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEY64333.1 - 7.6e-06 26.0 0.1 0.22 11.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY64333.1 - 0.00011 22.1 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KEY64333.1 - 0.0018 18.0 0.4 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY64333.1 - 0.0019 18.6 0.9 0.048 14.1 0.5 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KEY64333.1 - 0.0048 16.7 0.2 1.8 8.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY64333.1 - 0.0065 17.0 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KEY64333.1 - 0.015 15.4 1.4 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KEY64333.1 - 0.026 14.3 0.1 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KEY64333.1 - 0.032 14.0 1.1 0.59 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEY64333.1 - 0.043 13.9 1.9 0.95 9.5 0.2 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KEY64333.1 - 0.08 13.3 0.0 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KEY64333.1 - 0.11 11.9 0.5 11 5.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KEY64333.1 - 0.13 12.5 1.9 23 5.3 0.2 3.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KEY64333.1 - 0.49 10.3 1.9 1.2 9.0 0.1 2.4 3 0 0 3 3 3 0 NACHT domain ABC_membrane_2 PF06472.15 KEY64333.1 - 3.6 6.9 10.7 0.034 13.5 0.4 2.8 3 0 0 3 3 3 0 ABC transporter transmembrane region 2 DUF1749 PF08538.10 KEY64334.1 - 5.7e-83 278.4 0.0 2e-82 276.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KEY64334.1 - 6.1e-08 33.5 0.0 8.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY64334.1 - 3.3e-05 23.6 0.1 0.035 13.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY64334.1 - 0.00037 19.9 0.1 0.3 10.3 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY64334.1 - 0.004 16.7 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEY64334.1 - 0.013 15.3 0.0 1.5 8.6 0.1 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KEY64334.1 - 0.16 11.5 0.1 5.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase HEAT_2 PF13646.6 KEY64335.1 - 0.00079 19.8 6.5 1.8 9.0 0.0 6.8 7 1 0 7 7 7 1 HEAT repeats UME PF08064.13 KEY64335.1 - 0.0071 16.2 0.0 6.1 6.8 0.0 4.4 3 0 0 3 3 3 1 UME (NUC010) domain DUF3631 PF12307.8 KEY64335.1 - 0.0098 16.1 1.8 0.02 15.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3631) UTP15_C PF09384.10 KEY64335.1 - 0.085 12.5 4.7 0.75 9.5 0.0 4.1 5 0 0 5 5 5 0 UTP15 C terminal Xpo1 PF08389.12 KEY64335.1 - 1.9 8.6 7.6 10 6.2 0.1 4.8 5 2 0 5 5 5 0 Exportin 1-like protein NUDIX PF00293.28 KEY64336.1 - 1.3e-14 54.3 0.0 2.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KEY64336.1 - 1.4e-09 38.5 0.0 1.1e-08 35.7 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KEY64336.1 - 1.4e-06 27.9 0.6 2.6e-06 27.0 0.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.14 KEY64337.1 - 2.7e-37 126.4 15.9 4.8e-19 67.9 0.6 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KEY64337.1 - 0.019 15.8 0.4 3.3 8.5 0.1 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor HTH_Bact PF18768.1 KEY64337.1 - 1.4 8.5 3.6 0.77 9.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain CoaE PF01121.20 KEY64338.1 - 3.7e-44 150.5 0.0 1.4e-43 148.6 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KEY64338.1 - 0.00063 19.9 0.0 0.01 16.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY64338.1 - 0.0014 19.2 1.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Tim17 PF02466.19 KEY64339.1 - 4.9e-24 84.8 4.3 1.2e-23 83.6 4.6 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.12 KEY64339.1 - 0.26 10.8 5.8 4 6.9 5.5 2.1 1 1 1 2 2 2 0 5TMR of 5TMR-LYT LON_substr_bdg PF02190.16 KEY64342.1 - 2.7e-24 86.2 0.0 4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KEY64342.1 - 1.7e-13 50.1 22.6 3.4e-12 46.0 9.8 2.7 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY64342.1 - 9.7e-13 48.1 18.4 1.1e-06 28.6 7.5 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KEY64342.1 - 7.4e-11 41.9 22.1 7.1e-09 35.5 4.7 3.4 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY64342.1 - 1.2e-10 41.1 17.3 1.1e-08 34.8 7.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY64342.1 - 5.6e-10 38.9 20.0 1.6e-07 31.1 9.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY64342.1 - 6.3e-09 35.7 22.4 1.2e-06 28.4 9.4 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KEY64342.1 - 1e-08 35.3 24.9 5.2e-08 33.1 10.2 2.7 2 1 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 KEY64342.1 - 3.3e-06 26.8 18.3 2.3e-05 24.2 7.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 U-box PF04564.15 KEY64342.1 - 0.00011 22.3 0.0 0.0099 16.0 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-RING_4 PF14570.6 KEY64342.1 - 0.0011 18.7 9.8 0.0017 18.1 6.7 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KEY64342.1 - 0.0021 18.3 5.2 0.0021 18.3 5.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KEY64342.1 - 0.0047 17.0 15.5 0.0063 16.6 3.9 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KEY64342.1 - 0.011 15.5 3.6 0.011 15.5 3.6 2.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 KEY64342.1 - 0.012 15.3 6.7 0.012 15.3 6.7 2.3 3 0 0 3 3 3 0 P-11 zinc finger zinc_ribbon_2 PF13240.6 KEY64342.1 - 0.013 15.2 1.1 0.15 11.8 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KEY64342.1 - 0.065 13.3 0.3 0.065 13.3 0.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon HK97-gp10_like PF04883.12 KEY64342.1 - 0.14 13.2 0.0 0.28 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component zf-RING_6 PF14835.6 KEY64342.1 - 0.2 11.5 13.8 0.76 9.7 2.3 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KEY64342.1 - 2.1 8.3 5.6 2.5 8.1 1.4 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) tRNA-synt_1b PF00579.25 KEY64343.1 - 2.2e-58 197.9 0.0 2.9e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RTC4 PF14474.6 KEY64343.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 RTC4-like domain Complex1_LYR PF05347.15 KEY64344.1 - 3.5e-11 43.0 1.1 4.7e-11 42.6 1.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 KEY64345.1 - 2.8e-21 74.9 2.7 5.1e-21 74.1 2.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KEY64345.1 - 7e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEY64345.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY64346.1 - 1.7e-22 80.2 2.0 2.1e-22 79.9 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEY64346.1 - 1.9e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KEY64346.1 - 0.00032 21.1 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KEY64346.1 - 0.048 13.3 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 KEY64347.1 - 3.2e-14 52.6 0.0 7.9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KEY64347.1 - 2.5e-09 36.9 0.8 5.5e-09 35.8 0.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEY64347.1 - 0.00016 21.7 0.5 0.00068 19.7 0.5 2.1 1 0 0 1 1 1 1 G-patch domain CBM60 PF16841.5 KEY64347.1 - 0.095 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Peptidase_C54 PF03416.19 KEY64348.1 - 2.8e-91 305.8 0.0 3.6e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.31 KEY64349.1 - 2.1e-24 85.4 1.4 2.1e-24 85.4 1.4 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KEY64349.1 - 1.3e-11 44.5 8.8 2.7e-10 40.2 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY64349.1 - 5.7e-11 42.4 8.0 1.2e-08 35.0 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KEY64349.1 - 6.9e-09 36.0 7.2 0.0003 21.1 0.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEY64349.1 - 3.3e-07 30.6 3.8 0.013 16.3 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY64349.1 - 1.8e-06 28.0 7.4 0.017 15.6 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KEY64349.1 - 1.1e-05 25.3 5.9 0.02 14.9 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KEY64349.1 - 0.0077 16.9 0.9 7 7.4 0.1 2.8 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 KEY64349.1 - 0.04 14.0 0.3 3.9 7.5 0.1 2.6 2 0 0 2 2 2 0 CpXC protein RPT PF13446.6 KEY64349.1 - 0.048 13.6 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.6 KEY64349.1 - 0.05 14.1 0.4 4.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain SPX PF03105.19 KEY64350.1 - 6.5e-54 184.3 0.1 1.6e-53 183.0 0.1 1.6 1 1 0 1 1 1 1 SPX domain zf-C3HC4_2 PF13923.6 KEY64350.1 - 2e-07 30.7 9.6 4.6e-07 29.6 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY64350.1 - 6.1e-07 29.2 10.2 1.4e-06 28.0 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY64350.1 - 1.2e-06 28.3 9.8 2.5e-06 27.3 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY64350.1 - 4.1e-06 26.8 9.6 4.1e-06 26.8 9.6 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KEY64350.1 - 1.2e-05 25.5 11.7 8.2e-05 22.9 11.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KEY64350.1 - 0.00011 22.1 7.9 0.00028 20.8 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEY64350.1 - 0.00014 21.7 10.5 0.00064 19.6 10.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain HTH_Tnp_1 PF01527.20 KEY64350.1 - 0.024 14.9 0.3 0.094 13.0 0.2 2.1 2 0 0 2 2 2 0 Transposase Prok-RING_4 PF14447.6 KEY64350.1 - 0.051 13.5 11.2 0.49 10.3 10.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 KEY64350.1 - 0.055 13.6 1.1 0.13 12.4 1.1 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 KEY64350.1 - 0.37 10.6 10.3 0.11 12.4 5.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KEY64350.1 - 0.64 10.4 10.7 2.7 8.3 10.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEY64350.1 - 1.7 8.8 5.4 5.1 7.2 5.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cys_Met_Meta_PP PF01053.20 KEY64351.1 - 7.1e-29 100.5 0.0 9.5e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEY64351.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II EMG1 PF03587.14 KEY64353.1 - 2.3e-78 262.3 0.0 2.7e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase 2-oxoacid_dh PF00198.23 KEY64354.1 - 4.5e-80 268.5 0.6 7.1e-80 267.8 0.1 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEY64354.1 - 1.3e-17 63.4 2.3 2.7e-17 62.4 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEY64354.1 - 0.00082 19.1 1.0 0.024 14.4 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like Trypan_PARP PF05887.11 KEY64354.1 - 0.49 10.4 17.2 0.87 9.6 17.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3614 PF12267.8 KEY64354.1 - 0.58 10.6 6.9 1.3 9.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Presenilin PF01080.17 KEY64354.1 - 1.3 7.7 10.3 1.9 7.1 10.3 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KEY64354.1 - 1.4 7.5 8.9 2 7.0 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KEY64354.1 - 2.8 6.7 12.1 3.9 6.2 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 KEY64354.1 - 3.5 7.4 11.6 4.9 6.9 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 KEY64354.1 - 6.7 4.7 8.8 8.3 4.4 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM76 PF16046.5 KEY64354.1 - 8.6 5.6 12.0 29 3.9 9.7 2.0 2 0 0 2 2 2 0 FAM76 protein Ribosomal_S17 PF00366.20 KEY64355.1 - 3.3e-21 75.1 1.7 3.3e-21 75.1 1.7 2.2 2 1 0 2 2 2 1 Ribosomal protein S17 PDCD7 PF16021.5 KEY64355.1 - 0.00026 20.2 4.4 0.00037 19.7 4.4 1.2 1 0 0 1 1 1 1 Programmed cell death protein 7 AAA PF00004.29 KEY64356.1 - 1.9e-38 131.9 0.0 4e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KEY64356.1 - 2.6e-09 37.0 0.0 2.8e-08 33.6 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KEY64356.1 - 1.2e-05 25.0 0.0 0.00037 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KEY64356.1 - 1.4e-05 25.4 0.5 0.00085 19.6 0.2 3.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KEY64356.1 - 8.6e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY64356.1 - 0.00041 20.8 0.3 0.0025 18.2 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KEY64356.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KEY64356.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KEY64356.1 - 0.0029 17.6 0.2 0.0097 15.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEY64356.1 - 0.0037 16.7 0.1 0.0098 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEY64356.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KEY64356.1 - 0.0088 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KEY64356.1 - 0.0091 16.2 0.0 0.038 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY64356.1 - 0.038 14.3 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY64356.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY64356.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEY64356.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEY64356.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEY64356.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KEY64356.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KEY64356.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KEY64356.1 - 0.14 11.6 0.1 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 KEY64356.1 - 0.16 12.4 0.1 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase COG6 PF06419.11 KEY64357.1 - 1.8e-203 677.2 2.6 2.1e-203 677.0 2.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.16 KEY64357.1 - 0.1 11.7 4.0 0.07 12.3 0.2 2.5 2 1 0 2 2 2 0 RmuC family COG2 PF06148.11 KEY64357.1 - 0.77 9.8 7.3 0.29 11.2 0.5 3.5 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 APG9 PF04109.16 KEY64358.1 - 1.7e-194 647.3 16.0 2.1e-194 647.0 16.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.27 KEY64358.1 - 4.3e-66 218.9 6.3 4.9e-22 77.7 0.3 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein IBV_3B PF03622.13 KEY64358.1 - 0.34 11.1 1.0 8.2 6.7 0.4 3.1 3 0 0 3 3 3 0 IBV 3B protein DnaJ PF00226.31 KEY64359.1 - 4.7e-21 74.7 1.2 4.7e-21 74.7 1.2 3.0 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 KEY64359.1 - 1.7e-16 59.2 0.1 0.0012 18.6 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEY64359.1 - 2.5e-15 56.4 0.1 0.00034 20.7 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY64359.1 - 2.4e-13 49.1 12.7 0.015 15.4 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY64359.1 - 3.6e-10 39.8 11.4 0.044 14.6 0.0 7.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY64359.1 - 5.9e-10 39.5 11.6 0.0043 17.5 0.0 5.9 3 1 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEY64359.1 - 1.3e-09 37.8 10.4 9.8e-05 22.5 0.1 6.4 8 0 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY64359.1 - 2.8e-09 37.1 10.4 0.079 13.2 0.4 5.5 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KEY64359.1 - 1.2e-08 34.5 10.0 0.026 14.7 0.0 6.6 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY64359.1 - 1.5e-07 31.9 18.8 0.32 11.7 0.0 5.9 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY64359.1 - 9.5e-05 22.0 12.1 0.037 13.7 0.0 5.7 4 2 2 6 6 6 2 TPR repeat TPR_6 PF13174.6 KEY64359.1 - 0.00028 21.3 18.8 0.61 10.8 0.0 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY64359.1 - 0.0003 20.6 4.4 0.32 11.1 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KEY64359.1 - 0.00038 19.3 1.4 0.021 13.6 2.0 2.6 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 KEY64359.1 - 0.0015 18.8 12.1 0.23 11.8 0.3 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KEY64359.1 - 0.63 10.5 3.9 26 5.3 0.0 3.3 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation GAS PF13851.6 KEY64360.1 - 0.03 13.7 4.8 0.36 10.2 0.4 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TEX12 PF15219.6 KEY64360.1 - 0.035 14.4 0.1 0.16 12.3 0.1 2.1 1 1 0 1 1 1 0 Testis-expressed 12 Dor1 PF04124.12 KEY64360.1 - 0.035 12.8 1.5 0.057 12.1 1.5 1.2 1 0 0 1 1 1 0 Dor1-like family Phlebovirus_NSM PF07246.11 KEY64360.1 - 0.044 13.1 0.3 0.064 12.6 0.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.9 KEY64360.1 - 0.051 13.6 6.3 0.79 9.7 5.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Takusan PF04822.13 KEY64360.1 - 0.086 12.7 4.8 4.8 7.1 0.2 3.1 2 1 1 3 3 3 0 Takusan TPR_MLP1_2 PF07926.12 KEY64360.1 - 0.16 12.1 5.4 7 6.7 0.1 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.13 KEY64360.1 - 0.19 11.6 2.6 5 7.0 0.6 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region BLOC1_2 PF10046.9 KEY64360.1 - 0.2 12.0 3.0 4.3 7.7 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 KEY64360.1 - 0.28 10.8 5.0 1.3 8.5 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Vac14_Fig4_bd PF11916.8 KEY64361.1 - 6.3e-80 267.0 5.6 6.3e-80 267.0 5.6 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KEY64361.1 - 2.4e-44 149.9 0.0 8.4e-41 138.5 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KEY64361.1 - 2e-09 36.9 0.3 0.00063 19.8 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KEY64361.1 - 3.3e-08 33.9 3.8 0.001 19.5 0.2 5.2 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 KEY64361.1 - 4.8e-07 30.0 0.3 0.019 15.0 0.3 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY64361.1 - 0.00055 20.3 0.7 0.73 10.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 KEY64361.1 - 0.0049 16.9 0.0 0.49 10.5 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.24 KEY64362.1 - 2.6e-29 102.8 21.8 3.9e-29 102.3 21.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEY64362.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KEY64363.1 - 3.9e-66 223.3 5.7 5.6e-66 222.8 5.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEY64363.1 - 1.9e-38 131.1 0.2 8.8e-38 129.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEY64363.1 - 1.4e-24 86.5 10.2 2.3e-21 76.2 1.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY64363.1 - 5.5e-11 42.5 3.2 1.4e-06 28.4 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY64363.1 - 1.2e-09 38.0 10.4 3e-09 36.8 0.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KEY64363.1 - 1.6e-09 37.4 8.0 1.1e-07 31.3 3.5 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEY64363.1 - 1.8e-08 33.9 8.9 6.5e-07 28.8 2.5 3.2 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 KEY64363.1 - 1.1e-07 31.4 2.2 0.0094 15.3 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEY64363.1 - 2.9e-07 30.1 4.5 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY64363.1 - 4.1e-06 25.8 12.7 8.8e-05 21.4 1.7 4.0 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 KEY64363.1 - 1.2e-05 25.1 14.1 0.0019 17.9 0.4 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY64363.1 - 2.8e-05 23.4 2.1 0.0014 17.7 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEY64363.1 - 3.4e-05 23.2 4.9 0.00017 20.9 0.1 2.6 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.6 KEY64363.1 - 0.00014 21.2 0.3 0.47 9.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KEY64363.1 - 0.0002 20.8 8.0 0.044 13.0 0.8 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 KEY64363.1 - 0.0064 16.9 3.2 0.85 10.1 0.1 3.1 2 1 0 2 2 2 1 Putative NAD(P)-binding FMO-like PF00743.19 KEY64363.1 - 0.076 11.4 0.1 0.13 10.6 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KEY64363.1 - 0.48 9.2 6.9 0.063 12.1 0.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KEY64363.1 - 0.95 9.3 7.3 0.37 10.7 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIF4G PF02854.19 KEY64364.1 - 3.3e-20 72.6 0.1 1.1e-19 71.0 0.1 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KEY64364.1 - 2.2e-12 46.9 0.2 9.6e-10 38.4 0.0 2.8 2 1 0 2 2 2 2 MA3 domain Spem1 PF15670.5 KEY64364.1 - 8.8 5.8 7.4 0.37 10.3 0.6 2.1 3 0 0 3 3 3 0 Spermatid maturation protein 1 SRP14 PF02290.15 KEY64365.1 - 5.7e-23 81.1 0.2 8.7e-23 80.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein RRM_1 PF00076.22 KEY64366.1 - 9.1e-53 176.0 0.0 3.1e-17 62.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KEY64366.1 - 1.3e-06 28.4 0.1 1.1 9.3 0.0 4.3 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.11 KEY64366.1 - 3.4e-05 23.8 0.0 1.5 8.9 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 KEY64366.1 - 5.2e-05 23.0 0.0 3.2 7.7 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif ATP-grasp_2 PF08442.10 KEY64366.1 - 0.00074 19.1 0.0 0.087 12.4 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain RRM_5 PF13893.6 KEY64366.1 - 0.0079 15.8 0.0 4.3 7.0 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KEY64366.1 - 0.021 14.6 0.0 22 4.8 0.0 3.1 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain SPOR PF05036.13 KEY64366.1 - 0.085 13.2 0.1 5.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Sporulation related domain PknH_C PF14032.6 KEY64366.1 - 0.1 12.4 0.0 56 3.5 0.0 3.0 3 0 0 3 3 3 0 PknH-like extracellular domain DbpA PF03880.15 KEY64366.1 - 0.19 11.7 0.0 1.4e+02 2.5 0.0 3.4 4 0 0 4 4 4 0 DbpA RNA binding domain COQ9 PF08511.11 KEY64367.1 - 4.9e-32 109.5 0.0 7.6e-32 108.9 0.0 1.3 1 0 0 1 1 1 1 COQ9 AAA_23 PF13476.6 KEY64368.1 - 1.3e-18 68.3 2.1 1.3e-18 68.3 2.1 5.6 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.19 KEY64368.1 - 2.5e-18 66.3 11.4 1.4e-17 63.9 11.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KEY64368.1 - 1.8e-08 34.5 12.8 1.8e-08 34.5 12.8 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KEY64368.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 KEY64368.1 - 0.0015 18.8 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 KEY64368.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KEY64368.1 - 0.032 14.5 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 KEY64368.1 - 0.37 10.8 40.0 0.026 14.5 4.2 6.3 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) SGT1 PF07093.11 KEY64369.1 - 1.5e-94 317.5 22.5 1.2e-86 291.4 0.0 2.0 2 0 0 2 2 2 2 SGT1 protein Lsr2 PF11774.8 KEY64369.1 - 0.091 12.9 0.8 0.22 11.7 0.8 1.7 1 0 0 1 1 1 0 Lsr2 THUMP PF02926.17 KEY64370.1 - 3.8e-09 36.8 0.9 1.9e-06 28.0 0.1 2.5 2 1 0 2 2 2 2 THUMP domain TPP_enzyme_N PF02776.18 KEY64371.1 - 3.6e-33 114.6 0.0 5.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY64371.1 - 7.9e-16 58.0 0.0 1.8e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEY64371.1 - 2.3e-15 56.7 0.7 7.3e-15 55.1 0.1 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF956 PF06115.11 KEY64371.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Evr1_Alr PF04777.13 KEY64372.1 - 8.2e-31 106.4 0.1 2.2e-30 105.1 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.15 KEY64373.1 - 3.4e-37 128.0 0.0 4.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.16 KEY64374.1 - 3e-27 95.6 0.0 3.9e-14 53.1 0.1 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 KEY64375.1 - 6.9e-68 228.9 0.0 9.1e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64375.1 - 5.2e-32 111.1 0.0 6.8e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEY64375.1 - 0.00046 19.6 0.2 0.00078 18.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEY64375.1 - 0.0018 17.3 0.3 0.0033 16.4 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KEY64375.1 - 0.0098 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEY64375.1 - 0.024 14.5 0.2 0.056 13.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEY64375.1 - 0.086 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 KEY64375.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 KEY64375.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.15 KEY64376.1 - 4.9e-69 232.6 0.0 7.7e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEY64376.1 - 5.2e-24 84.0 0.1 1.7e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KEY64376.1 - 5.8e-17 61.5 4.7 9.9e-17 60.7 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KEY64376.1 - 2e-16 60.5 0.0 3.8e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KEY64376.1 - 8.1e-10 38.5 0.1 3.6e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KEY64376.1 - 0.018 14.5 0.1 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF1035 PF06281.12 KEY64377.1 - 0.0081 16.1 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1035) PsbY PF06298.11 KEY64377.1 - 0.0098 15.8 0.3 0.0098 15.8 0.3 1.7 2 0 0 2 2 2 1 Photosystem II protein Y (PsbY) Xpo1 PF08389.12 KEY64379.1 - 4.1e-06 26.9 4.2 2.9e-05 24.2 0.0 4.1 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 KEY64379.1 - 3e-05 23.8 1.9 0.00015 21.6 0.1 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain IFRD PF05004.13 KEY64379.1 - 0.0047 16.1 0.2 0.022 13.9 0.1 2.1 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF1917 PF08939.10 KEY64381.1 - 4.9e-79 265.9 0.1 7.7e-79 265.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Mhr1 PF12829.7 KEY64381.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Acetyltransf_1 PF00583.25 KEY64382.1 - 9.1e-18 64.6 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY64382.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY64382.1 - 4.7e-09 36.1 0.0 7.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KEY64382.1 - 1.3e-08 35.1 0.0 2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEY64382.1 - 1.5e-06 28.9 0.0 1.9e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY64382.1 - 5.8e-06 26.4 0.0 9.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEY64382.1 - 5.9e-06 26.0 0.0 7.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY64382.1 - 0.045 13.9 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KEY64382.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.15 KEY64383.1 - 4.5e-104 348.7 0.0 5.4e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1778 PF08681.11 KEY64383.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2013 PF09431.10 KEY64384.1 - 7e-50 168.8 2.4 7e-50 168.8 2.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF4503 PF14951.6 KEY64384.1 - 0.062 11.7 0.1 0.094 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) PH PF00169.29 KEY64385.1 - 3.4e-05 24.3 0.1 8.5e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 PH domain MCPVI PF02993.14 KEY64385.1 - 0.0044 16.9 0.3 0.013 15.3 0.3 1.8 1 0 0 1 1 1 1 Minor capsid protein VI Prominin PF05478.11 KEY64385.1 - 0.23 9.4 0.1 0.34 8.8 0.1 1.1 1 0 0 1 1 1 0 Prominin Gar1 PF04410.14 KEY64386.1 - 3.1e-37 127.7 0.0 4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 KEY64387.1 - 6.7e-15 55.6 0.3 1.8e-14 54.2 0.3 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 KEY64388.1 - 5.2e-158 526.1 0.0 6.9e-158 525.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KEY64388.1 - 0.0033 17.4 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KEY64388.1 - 0.97 9.5 7.3 0.082 13.0 1.7 1.9 2 1 0 2 2 2 0 Metallo-peptidase family M12 Whi5 PF08528.11 KEY64389.1 - 7.6e-07 28.6 0.9 1.1e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Whi5 like Syndecan PF01034.20 KEY64390.1 - 0.13 12.2 0.9 0.24 11.4 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain PNP_UDP_1 PF01048.20 KEY64393.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily SurE PF01975.17 KEY64394.1 - 1e-19 71.1 0.0 1.3e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE H_lectin PF09458.10 KEY64395.1 - 4.3e-18 65.3 1.6 1.1e-17 64.0 0.1 2.2 2 0 0 2 2 2 1 H-type lectin domain Matrilin_ccoil PF10393.9 KEY64395.1 - 0.053 13.4 0.4 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FAD_binding_4 PF01565.23 KEY64400.1 - 4.1e-19 68.7 0.2 7.2e-19 67.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY64400.1 - 9.8e-08 32.0 0.2 2.1e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.18 KEY64401.1 - 3.5e-20 72.2 0.1 5.1e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KEY64401.1 - 0.025 14.7 0.3 0.061 13.5 0.3 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Zn_clus PF00172.18 KEY64401.1 - 0.067 13.3 5.6 0.12 12.6 5.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 KEY64401.1 - 0.11 12.4 1.4 0.16 11.8 1.4 1.2 1 0 0 1 1 1 0 SPX domain Sugar_tr PF00083.24 KEY64402.1 - 1.4e-92 310.9 20.4 1.8e-92 310.6 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64402.1 - 8.8e-30 103.8 33.5 1.4e-27 96.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2063 PF09836.9 KEY64402.1 - 0.014 15.6 0.0 0.11 12.7 0.0 2.3 3 0 0 3 3 3 0 Putative DNA-binding domain DUF2754 PF10953.8 KEY64402.1 - 7.4 6.9 8.4 0.6 10.4 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) adh_short_C2 PF13561.6 KEY64403.1 - 5.1e-56 189.8 0.0 6.3e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY64403.1 - 8.2e-40 136.3 0.1 1e-39 136.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY64403.1 - 2.6e-12 47.0 0.1 3.7e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KEY64403.1 - 0.0095 15.3 0.1 0.026 13.9 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY64403.1 - 0.014 14.8 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY64403.1 - 0.02 14.3 0.1 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KEY64403.1 - 0.034 14.4 0.0 0.081 13.2 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KEY64403.1 - 0.046 12.9 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cas_APE2256 PF09651.10 KEY64403.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Zeta_toxin PF06414.12 KEY64404.1 - 7.2e-05 22.2 0.2 0.00024 20.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KEY64404.1 - 0.00016 22.2 0.0 0.0005 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY64404.1 - 0.00022 21.7 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KEY64404.1 - 0.00038 20.7 1.1 0.00079 19.6 0.0 2.1 3 1 0 3 3 2 1 AAA domain AAA PF00004.29 KEY64404.1 - 0.00047 20.6 0.0 0.0008 19.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KEY64404.1 - 0.00059 19.8 0.2 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KEY64404.1 - 0.00071 19.9 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEY64404.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 KEY64404.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.6 KEY64404.1 - 0.002 18.6 0.1 0.019 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY64404.1 - 0.0045 16.7 0.1 0.0067 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KEY64404.1 - 0.0064 16.3 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 KEY64404.1 - 0.0066 16.8 0.1 0.01 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY64404.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KTI12 PF08433.10 KEY64404.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NACHT PF05729.12 KEY64404.1 - 0.008 16.1 0.1 0.059 13.3 0.0 2.1 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KEY64404.1 - 0.0092 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KEY64404.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEY64404.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY64404.1 - 0.02 15.1 1.0 0.057 13.7 0.0 2.2 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KEY64404.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 KEY64404.1 - 0.037 13.3 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TsaE PF02367.17 KEY64404.1 - 0.043 13.8 0.0 0.091 12.8 0.0 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KEY64404.1 - 0.058 13.0 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEY64404.1 - 0.059 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY64404.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KEY64404.1 - 0.076 12.9 1.2 0.45 10.3 1.2 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KEY64404.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit 6PF2K PF01591.18 KEY64404.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_11 PF13086.6 KEY64404.1 - 0.17 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEY64404.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KEY64404.1 - 0.21 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_PrkA PF08298.11 KEY64404.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain ADH_N PF08240.12 KEY64405.1 - 1.8e-31 108.2 0.4 1.8e-31 108.2 0.4 2.5 2 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY64405.1 - 2e-23 82.8 1.1 3.2e-23 82.1 1.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY64405.1 - 2.4e-08 33.8 0.3 3.2e-07 30.1 0.3 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY64405.1 - 1.2e-05 26.4 0.0 4.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KEY64405.1 - 0.00077 20.1 0.1 0.0019 18.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KEY64405.1 - 0.0055 16.1 0.1 0.0094 15.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.20 KEY64405.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UDPG_MGDP_dh_N PF03721.14 KEY64405.1 - 0.023 14.3 0.2 0.047 13.3 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TmoB PF06234.12 KEY64405.1 - 0.035 14.2 0.1 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Methyltransf_31 PF13847.6 KEY64405.1 - 0.037 13.8 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 KEY64405.1 - 0.038 13.9 0.1 0.08 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_11 PF08241.12 KEY64405.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEY64405.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KEY64405.1 - 0.31 11.1 3.3 16 5.5 1.4 2.3 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short_C2 PF13561.6 KEY64406.1 - 3e-60 203.7 2.1 3.7e-60 203.4 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY64406.1 - 1.7e-48 164.6 1.5 2.3e-48 164.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY64406.1 - 3.1e-16 59.8 1.9 4.3e-16 59.4 1.9 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KEY64406.1 - 0.00085 18.7 0.5 0.091 12.1 0.0 2.3 1 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KEY64406.1 - 0.0013 18.2 1.0 0.0042 16.6 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY64406.1 - 0.0066 15.9 0.6 0.0086 15.5 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Tom22 PF04281.13 KEY64406.1 - 0.089 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 adh_short PF00106.25 KEY64407.1 - 6.3e-23 81.2 0.0 3.7e-22 78.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64407.1 - 1.5e-16 60.7 0.0 3.3e-16 59.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64407.1 - 4.8e-08 33.1 0.1 8.8e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY64407.1 - 0.12 11.8 0.0 0.49 9.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KEY64408.1 - 2.2e-43 148.9 0.0 3.2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.7 KEY64410.1 - 3.3e-06 27.9 0.1 4.9e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KEY64410.1 - 2e-05 24.3 0.3 0.00024 20.7 0.2 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.11 KEY64410.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 KEY64410.1 - 0.027 14.1 0.1 0.2 11.3 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KEY64410.1 - 0.042 12.5 0.3 0.27 9.8 0.3 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KEY64410.1 - 0.076 12.9 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.25 KEY64411.1 - 3.1e-29 101.8 0.0 4.2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64411.1 - 3.5e-19 69.3 0.0 5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64411.1 - 5e-06 26.5 0.0 4.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY64411.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Big_3 PF07523.12 KEY64413.1 - 6.3e-08 32.8 2.0 1.1e-07 32.0 0.9 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Glyco_hydro_43 PF04616.14 KEY64413.1 - 1.4e-06 27.9 3.3 2.5e-06 27.0 3.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amidase PF01425.21 KEY64414.1 - 5.1e-56 190.5 0.2 3e-53 181.4 0.2 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_43 PF04616.14 KEY64414.1 - 6.7e-40 137.2 5.5 1.2e-39 136.4 5.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY64414.1 - 1.1e-25 90.6 0.2 2.1e-25 89.6 0.1 1.6 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain CBM_1 PF00734.18 KEY64414.1 - 1.5e-10 40.9 15.0 1.5e-10 40.9 15.0 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain YtxH PF12732.7 KEY64415.1 - 0.13 12.8 13.1 77 3.9 9.1 4.4 3 1 0 3 3 3 0 YtxH-like protein Tape_meas_lam_C PF09718.10 KEY64415.1 - 0.16 12.1 3.3 12 6.1 0.9 2.9 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_r1t_holin PF16945.5 KEY64415.1 - 0.83 9.9 11.3 1.6 9.0 9.0 2.6 2 1 0 2 2 2 0 Putative lactococcus lactis phage r1t holin ISG65-75 PF11727.8 KEY64415.1 - 1.2 8.3 5.5 0.46 9.7 2.8 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Ribosomal_S20p PF01649.18 KEY64415.1 - 1.2 9.8 5.9 4.5 8.0 5.9 2.0 1 1 0 1 1 1 0 Ribosomal protein S20 EspB PF05802.11 KEY64415.1 - 2.8 7.9 16.7 0.34 10.9 7.4 3.2 2 1 1 3 3 3 0 Enterobacterial EspB protein HSP9_HSP12 PF04119.12 KEY64415.1 - 7.2 7.1 11.9 61 4.1 0.4 4.6 4 1 1 5 5 5 0 Heat shock protein 9/12 PP_M1 PF03012.14 KEY64416.1 - 0.049 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoprotein Roughex PF06020.11 KEY64416.1 - 8.3 5.4 5.6 26 3.8 3.8 2.0 2 0 0 2 2 2 0 Drosophila roughex protein Amidase PF01425.21 KEY64417.1 - 3e-17 62.7 2.4 4.1e-15 55.7 2.3 2.1 2 0 0 2 2 2 2 Amidase Sugar_tr PF00083.24 KEY64419.1 - 2e-85 287.4 18.9 2.5e-85 287.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64419.1 - 1.3e-22 80.2 33.7 6.3e-20 71.4 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY64419.1 - 0.0026 16.3 1.3 0.0044 15.5 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2368 PF10166.9 KEY64419.1 - 0.15 11.7 0.4 0.31 10.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) zf-C2H2 PF00096.26 KEY64420.1 - 2.6e-13 49.6 31.0 1.9e-05 24.9 1.7 4.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY64420.1 - 1.1e-08 35.2 25.2 0.00042 20.9 1.0 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY64420.1 - 0.00027 21.2 26.1 0.0077 16.6 4.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KEY64420.1 - 0.019 15.6 2.7 1.5 9.5 1.5 2.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KEY64420.1 - 0.037 13.8 0.3 0.037 13.8 0.3 3.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KEY64420.1 - 0.039 13.8 1.7 0.039 13.8 1.7 2.4 1 1 1 2 2 2 0 zinc-finger of a C2HC-type Ustilago_mating PF05722.12 KEY64420.1 - 0.23 11.0 3.4 6.9 6.1 1.3 2.3 2 0 0 2 2 2 0 Ustilago B locus mating-type protein zf-BED PF02892.15 KEY64420.1 - 0.25 11.4 12.3 0.31 11.1 7.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_aberr PF17017.5 KEY64420.1 - 0.32 11.1 6.8 0.8 9.8 6.5 1.8 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KEY64420.1 - 6.8 7.1 10.7 2 8.7 6.7 2.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon DDHD PF02862.17 KEY64421.1 - 1.4e-22 80.9 0.1 4.4e-18 66.3 0.0 3.1 2 1 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 KEY64421.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KEY64421.1 - 0.12 12.1 0.0 0.34 10.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DEAD_2 PF06733.15 KEY64422.1 - 4.4e-55 186.0 0.6 4.4e-55 186.0 0.6 1.9 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KEY64422.1 - 1.9e-48 164.7 2.3 3.3e-45 154.1 0.6 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KEY64422.1 - 5.3e-43 147.1 0.0 1.9e-42 145.3 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KEY64422.1 - 3.8e-05 23.8 0.1 0.0013 18.8 0.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KEY64422.1 - 0.00064 18.5 0.0 0.0044 15.8 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KEY64422.1 - 0.00092 19.0 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY64422.1 - 0.023 14.9 0.2 3.6 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KEY64422.1 - 0.047 13.1 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD_C PF13361.6 KEY64422.1 - 0.1 12.0 0.2 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DSPc PF00782.20 KEY64423.1 - 7.1e-21 74.4 0.0 2.4e-13 50.0 0.1 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEY64423.1 - 0.004 16.7 0.0 0.017 14.7 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase ANAPC4_WD40 PF12894.7 KEY64424.1 - 0.00092 19.5 0.0 0.44 10.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY64424.1 - 0.017 16.0 0.3 9.4 7.3 0.0 3.9 4 1 0 4 4 4 0 WD domain, G-beta repeat Cupin_8 PF13621.6 KEY64425.1 - 2.1e-33 116.1 0.0 3.1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KEY64425.1 - 5.5e-21 75.4 0.0 8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KEY64425.1 - 2.6e-06 27.3 0.2 4.3e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Cupin_4 PF08007.12 KEY64425.1 - 0.0031 17.0 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.6 KEY64425.1 - 0.0088 16.0 0.1 4.4 7.4 0.0 3.2 3 0 0 3 3 3 2 Kelch motif MHYT PF03707.16 KEY64426.1 - 3.4e-23 81.6 25.5 6.5e-10 39.0 4.0 5.3 5 0 0 5 5 5 4 Bacterial signalling protein N terminal repeat Saf_2TM PF18303.1 KEY64426.1 - 0.091 12.3 0.1 0.091 12.3 0.1 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DAO PF01266.24 KEY64427.1 - 3e-52 178.4 0.0 4.1e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEY64427.1 - 4.9e-43 146.0 0.0 9.7e-43 145.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KEY64427.1 - 2.2e-06 27.0 1.1 1.3e-05 24.5 1.1 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEY64427.1 - 9.2e-06 25.2 0.1 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY64427.1 - 0.00038 19.8 0.1 0.00088 18.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY64427.1 - 0.0061 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEY64427.1 - 0.0074 15.6 0.6 0.059 12.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KEY64427.1 - 0.036 13.2 0.1 0.16 11.0 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KEY64427.1 - 0.048 12.9 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY64427.1 - 0.059 13.9 0.2 0.15 12.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEY64427.1 - 0.076 12.9 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KEY64427.1 - 0.082 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEY64427.1 - 0.11 11.2 0.4 0.17 10.6 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein RGS PF00615.19 KEY64428.1 - 1.6e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.19 KEY64429.1 - 1.9e-20 73.7 0.0 5.1e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_3 PF01494.19 KEY64430.1 - 4e-71 240.1 0.0 5.2e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEY64430.1 - 2.9e-39 134.7 0.1 7.2e-39 133.5 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KEY64430.1 - 0.0019 17.5 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY64430.1 - 0.012 14.7 0.0 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY64430.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KEY64430.1 - 0.02 14.5 0.2 0.073 12.6 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KEY64430.1 - 0.023 15.2 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KEY64430.1 - 0.078 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.17 KEY64430.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KEY64430.1 - 0.1 12.1 0.0 0.46 10.0 0.0 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEY64430.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KEY64430.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Rick_17kDa_Anti PF05433.15 KEY64432.1 - 0.9 9.5 15.7 6.5 6.7 14.3 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain WD40 PF00400.32 KEY64433.1 - 1.1e-23 83.0 17.3 6.9e-08 33.0 0.1 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat MFS_1 PF07690.16 KEY64433.1 - 1.2e-21 77.0 58.1 5e-11 42.1 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 KEY64433.1 - 5.5e-05 23.4 0.1 0.7 10.2 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY64433.1 - 0.095 11.6 1.0 0.44 9.5 0.2 2.5 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Transket_pyr PF02779.24 KEY64434.1 - 9.9e-62 207.8 0.0 1.7e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KEY64434.1 - 2.9e-57 193.9 0.0 4.1e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KEY64434.1 - 1.2e-54 184.2 0.0 2e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KEY64434.1 - 1.4e-19 69.3 1.3 2.9e-19 68.4 1.3 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 KEY64434.1 - 0.065 13.8 0.8 0.19 12.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 BSD PF03909.17 KEY64435.1 - 2.3e-29 101.2 0.3 1.9e-13 50.2 0.1 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KEY64435.1 - 3e-26 91.5 0.2 9.9e-26 89.9 0.0 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain AAA PF00004.29 KEY64436.1 - 7.2e-38 130.0 0.0 1.4e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY64436.1 - 1.4e-09 37.6 0.3 3.8e-09 36.2 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEY64436.1 - 1.3e-05 25.0 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY64436.1 - 7.6e-05 23.2 0.0 0.00076 19.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY64436.1 - 0.0003 21.1 0.2 0.045 14.0 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KEY64436.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY64436.1 - 0.0032 17.5 0.1 0.0099 15.9 0.1 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KEY64436.1 - 0.0049 16.3 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein TsaE PF02367.17 KEY64436.1 - 0.0053 16.7 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEY64436.1 - 0.0055 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY64436.1 - 0.0089 16.6 0.0 0.046 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEY64436.1 - 0.0092 15.4 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEY64436.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEY64436.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KEY64436.1 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KEY64436.1 - 0.05 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEY64436.1 - 0.15 12.0 0.1 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KEY64436.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KEY64436.1 - 0.18 11.4 0.1 0.71 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KEY64437.1 - 4.5e-07 29.9 12.3 7.5e-07 29.2 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY64437.1 - 0.00045 19.1 0.8 0.00058 18.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain CLZ PF16526.5 KEY64438.1 - 0.00082 19.7 2.8 4 7.9 0.0 3.8 4 0 0 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KEY64438.1 - 0.0056 17.0 4.3 0.31 11.4 1.3 3.1 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nmad5 PF18757.1 KEY64438.1 - 0.0099 16.1 0.4 0.017 15.3 0.4 1.4 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 DUF4140 PF13600.6 KEY64438.1 - 0.028 14.8 4.0 0.11 13.0 2.1 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 KEY64438.1 - 0.11 11.1 1.7 0.34 9.5 1.7 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Med9 PF07544.13 KEY64438.1 - 0.18 11.9 2.6 6.6 6.9 0.9 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 KEY64438.1 - 0.22 11.9 1.3 65 4.0 0.1 4.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Nup54_C PF18437.1 KEY64438.1 - 0.23 11.4 1.2 51 3.9 0.0 3.2 3 0 0 3 3 3 0 Nup54 C-terminal interacting domain Nsp1_C PF05064.13 KEY64438.1 - 0.46 10.3 5.2 4.8 7.0 1.0 2.7 3 0 0 3 3 3 0 Nsp1-like C-terminal region FTA4 PF13093.6 KEY64438.1 - 1.4 8.7 6.7 2.1 8.2 6.7 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4407 PF14362.6 KEY64438.1 - 2.6 7.3 7.7 6.6 6.0 5.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HalX PF08663.10 KEY64438.1 - 3.6 8.0 10.0 23 5.4 5.1 3.5 2 1 0 2 2 2 0 HalX domain ATP-synt_ab PF00006.25 KEY64439.1 - 2e-61 207.3 0.0 2.9e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEY64439.1 - 8.9e-23 80.6 0.9 2.8e-22 79.0 0.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KEY64439.1 - 0.014 15.4 0.5 0.032 14.1 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 KEY64439.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEY64439.1 - 0.021 14.0 0.4 0.08 12.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KEY64439.1 - 0.034 14.1 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KEY64439.1 - 0.038 13.3 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KEY64439.1 - 0.071 13.5 0.1 0.26 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KEY64439.1 - 0.091 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 KEY64439.1 - 0.093 12.6 0.6 0.52 10.2 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 KEY64439.1 - 0.093 13.1 0.8 0.48 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain Alpha-amylase_C PF02806.18 KEY64440.1 - 2.5e-27 95.2 0.0 6.5e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KEY64440.1 - 4.1e-17 62.3 0.7 1.2e-16 60.8 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KEY64440.1 - 4.3e-15 56.1 0.3 9.2e-12 45.2 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Cellulase PF00150.18 KEY64440.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 KEY64440.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 KEY64441.1 - 2e-32 112.6 0.0 1e-31 110.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEY64441.1 - 4.3e-12 46.6 0.0 8.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KEY64441.1 - 7.4e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KEY64441.1 - 2.2e-07 30.9 0.1 9.4e-07 28.9 0.0 2.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KEY64441.1 - 3.7e-05 22.9 0.0 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 KEY64441.1 - 0.00043 20.6 1.2 0.0028 17.9 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY64441.1 - 0.0017 18.8 0.1 0.015 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KEY64441.1 - 0.0078 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEY64441.1 - 0.0085 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEY64441.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 KEY64441.1 - 0.051 13.9 0.0 0.19 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEY64441.1 - 0.067 12.6 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KEY64441.1 - 0.077 12.4 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 KEY64441.1 - 0.1 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KEY64441.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KEY64441.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 KEY64441.1 - 0.31 11.6 0.1 0.31 11.6 0.1 2.0 2 1 0 2 2 1 0 AAA domain COX4 PF02936.14 KEY64442.1 - 3.6e-46 156.6 0.0 4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Fungal_trans PF04082.18 KEY64443.1 - 2.7e-07 29.9 0.1 4.3e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mus7 PF09462.10 KEY64444.1 - 2.9e-132 442.6 0.7 4.4e-132 442.0 0.7 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family ORC5_C PF14630.6 KEY64445.1 - 4.7e-86 288.8 0.0 5.9e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KEY64445.1 - 6.3e-16 59.2 0.1 1.8e-15 57.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KEY64445.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEY64445.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY64445.1 - 0.068 13.4 0.2 2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPT PF03151.16 KEY64446.1 - 9.1e-59 199.2 9.4 1.1e-58 198.9 9.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEY64446.1 - 1.8e-09 37.9 28.3 1.2e-05 25.5 9.9 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KEY64446.1 - 3.9e-06 26.3 9.9 7.3e-06 25.4 9.9 1.4 1 1 0 1 1 1 1 UAA transporter family DUF2070 PF09843.9 KEY64446.1 - 8.1 4.6 16.0 1.1 7.4 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF382 PF04037.13 KEY64447.1 - 5.8e-59 197.8 0.6 5.8e-59 197.8 0.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KEY64447.1 - 3.1e-19 68.6 4.4 6.7e-19 67.5 4.4 1.6 1 0 0 1 1 1 1 PSP VEFS-Box PF09733.9 KEY64448.1 - 6.7e-10 38.9 1.2 1.7e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 VEFS-Box of polycomb protein PHD PF00628.29 KEY64448.1 - 0.00045 20.1 4.6 0.0012 18.7 4.6 1.8 1 0 0 1 1 1 1 PHD-finger zf_C2H2_ZHX PF18387.1 KEY64448.1 - 0.0093 15.6 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KEY64448.1 - 0.047 14.4 0.1 0.13 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats MTHFR_C PF12225.8 KEY64448.1 - 0.085 12.5 0.8 0.2 11.3 0.8 1.6 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal LRR_4 PF12799.7 KEY64449.1 - 0.79 10.2 11.6 16 6.1 3.1 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Suf PF05843.14 KEY64449.1 - 2.7 7.9 5.0 0.92 9.4 0.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Arb2 PF09757.9 KEY64450.1 - 6.9e-100 333.4 0.1 9.4e-100 333.0 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KEY64450.1 - 6.2e-80 268.9 0.0 1e-79 268.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain F-box PF00646.33 KEY64451.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY64451.1 - 0.0047 16.8 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KEY64451.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box Brix PF04427.18 KEY64452.1 - 2.2e-36 125.8 0.1 2.9e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Ras PF00071.22 KEY64453.1 - 2.7e-63 212.4 0.2 3.2e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY64453.1 - 2.8e-35 121.1 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY64453.1 - 4.7e-13 49.0 0.1 6e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEY64453.1 - 7.9e-08 32.4 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY64453.1 - 0.00034 20.2 0.1 0.0019 17.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEY64453.1 - 0.00043 19.7 0.1 0.00069 19.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KEY64453.1 - 0.00051 20.0 0.9 0.017 15.0 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KEY64453.1 - 0.0028 17.9 0.0 0.019 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KEY64453.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KEY64453.1 - 0.018 15.1 0.1 0.047 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEY64453.1 - 0.018 15.4 0.1 0.031 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KEY64453.1 - 0.021 15.3 0.1 0.032 14.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KEY64453.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KEY64453.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KEY64453.1 - 0.095 12.5 0.6 0.15 11.9 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 KEY64453.1 - 0.1 12.7 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 KEY64453.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 KEY64453.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pex14_N PF04695.13 KEY64455.1 - 3.7e-30 105.6 0.5 3.7e-30 105.6 0.5 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.16 KEY64455.1 - 0.039 14.4 0.3 0.078 13.4 0.3 1.4 1 0 0 1 1 1 0 RecX family ATG16 PF08614.11 KEY64455.1 - 0.047 13.9 1.0 0.047 13.9 1.0 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PAPA-1 PF04795.12 KEY64456.1 - 1.3e-28 99.6 4.9 1.3e-28 99.6 4.9 3.5 4 1 0 4 4 4 1 PAPA-1-like conserved region DUF4106 PF13388.6 KEY64458.1 - 0.12 11.6 6.6 0.18 11.0 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Cloacin_immun PF03513.14 KEY64458.1 - 0.18 12.2 0.8 2.7 8.4 0.3 2.1 2 0 0 2 2 2 0 Cloacin immunity protein CCDC53 PF10152.9 KEY64458.1 - 0.91 9.9 10.4 0.26 11.7 7.3 1.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 KEY64458.1 - 1.1 7.8 3.6 1.1 7.8 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KEY64458.1 - 2.1 7.9 13.4 3.1 7.3 13.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PARM PF17061.5 KEY64458.1 - 6.7 6.8 16.3 9.6 6.2 16.3 1.1 1 0 0 1 1 1 0 PARM DUF4050 PF13259.6 KEY64459.1 - 1.8e-59 201.1 0.1 1.8e-59 201.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) AMP-binding PF00501.28 KEY64460.1 - 4.4e-75 252.9 0.1 9e-73 245.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KEY64460.1 - 3.2e-62 210.7 0.0 2.6e-35 122.0 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KEY64460.1 - 1.2e-22 80.0 0.1 2.2e-10 40.7 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.28 KEY64461.1 - 9.3e-97 324.3 0.0 1.1e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY64461.1 - 2.8e-12 47.5 0.0 5.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 KEY64462.1 - 7e-23 81.3 0.0 8.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY64462.1 - 8.7e-14 51.8 0.8 8.7e-14 51.8 0.8 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEY64462.1 - 0.00014 20.9 1.3 0.066 12.0 0.7 2.8 3 0 0 3 3 3 2 Tryptophan halogenase K_oxygenase PF13434.6 KEY64462.1 - 0.00028 20.1 0.4 0.00063 19.0 0.4 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KEY64462.1 - 0.0022 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEY64462.1 - 0.0049 16.2 3.4 0.12 11.5 0.7 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEY64462.1 - 0.012 15.0 0.3 1.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KEY64462.1 - 0.03 13.9 3.4 0.32 10.5 0.4 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY64462.1 - 0.031 13.5 3.0 0.053 12.8 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 KEY64462.1 - 0.042 12.9 2.1 1.6 7.7 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEY64462.1 - 0.058 13.4 1.4 39 4.2 0.1 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Acetyltransf_8 PF13523.6 KEY64463.1 - 4.7e-45 152.8 1.7 8.6e-45 152.0 1.7 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SPX PF03105.19 KEY64463.1 - 3.2e-41 142.5 8.6 1.4e-30 107.5 0.1 2.7 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 KEY64463.1 - 2e-35 122.8 34.4 2.9e-35 122.2 34.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KEY64463.1 - 8.2e-27 94.2 32.9 8.2e-27 94.2 32.9 2.0 2 1 0 2 2 2 1 Citrate transporter Rcd1 PF04078.13 KEY64463.1 - 0.04 13.2 1.2 0.85 8.9 0.1 2.2 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like Vps39_1 PF10366.9 KEY64464.1 - 7e-35 119.6 0.2 1.2e-33 115.7 0.0 2.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KEY64464.1 - 1.1e-26 93.4 0.0 4.5e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KEY64464.1 - 3.1e-16 59.8 0.0 1e-15 58.1 0.0 1.8 1 1 0 1 1 1 1 CNH domain HPIP PF15226.6 KEY64464.1 - 0.072 13.5 0.1 3.1 8.2 0.0 3.0 3 0 0 3 3 3 0 HCF-1 beta-propeller-interacting protein family DUF424 PF04242.13 KEY64464.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF424) TPR_1 PF00515.28 KEY64464.1 - 0.14 12.0 8.7 3.8 7.5 0.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KEY64464.1 - 0.84 9.5 10.3 0.99 9.3 0.7 3.9 3 1 1 4 4 4 0 Region in Clathrin and VPS ANAPC3 PF12895.7 KEY64464.1 - 2.4 8.4 6.6 11 6.3 0.5 3.7 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Gon7 PF08738.10 KEY64465.1 - 1.6e-09 37.8 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Gon7 family HbrB PF08539.11 KEY64466.1 - 3.3e-52 176.9 0.0 6.2e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 HbrB-like LIM_bind PF01803.16 KEY64467.1 - 1.4e-73 247.4 0.5 1.4e-73 247.4 0.5 4.9 2 1 2 4 4 4 1 LIM-domain binding protein Sulfotransfer_4 PF17784.1 KEY64468.1 - 5.1e-65 219.3 0.0 6.1e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY64468.1 - 1.6e-05 25.4 0.1 0.0054 17.1 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family ThrE PF06738.12 KEY64469.1 - 2e-72 243.4 7.3 9.9e-69 231.4 2.6 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KEY64469.1 - 6.5e-07 29.5 0.7 6.5e-07 29.5 0.7 3.4 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DUF2722 PF10846.8 KEY64470.1 - 4e-06 26.0 8.5 4.2e-06 26.0 0.3 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) DUF3292 PF11696.8 KEY64470.1 - 1.2 7.4 3.7 2 6.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RbpA PF13397.6 KEY64470.1 - 8 7.1 7.8 38 5.0 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase-binding protein HATPase_c PF02518.26 KEY64471.1 - 1.7e-30 105.8 0.0 3.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY64471.1 - 3.6e-20 72.2 0.1 1e-19 70.8 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY64471.1 - 1e-17 63.9 0.5 3.9e-17 62.0 0.5 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KEY64471.1 - 5.5e-12 46.4 3.2 7.2e-12 46.0 0.0 2.9 4 0 0 4 4 4 1 AAA ATPase domain GAF_2 PF13185.6 KEY64471.1 - 1.2e-11 45.1 0.0 5.2e-11 43.0 0.0 2.2 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KEY64471.1 - 3.7e-07 29.8 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KEY64471.1 - 3.3e-06 27.8 0.0 1.5e-05 25.6 0.0 2.3 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 KEY64471.1 - 9.9e-05 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 KEY64471.1 - 0.00043 20.1 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.6 KEY64471.1 - 0.00078 19.7 1.7 0.81 10.0 0.0 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat GAF_3 PF13492.6 KEY64471.1 - 0.0035 17.7 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 KEY64471.1 - 0.095 12.6 0.3 0.69 9.8 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KEY64471.1 - 0.19 12.0 0.3 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Amino_oxidase PF01593.24 KEY64472.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY64472.1 - 1.7e-06 28.1 0.1 3.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY64472.1 - 0.0073 15.6 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KEY64472.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEY64472.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KEY64472.1 - 0.082 12.1 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY64472.1 - 0.16 11.2 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEY64472.1 - 0.22 10.7 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPT PF03151.16 KEY64473.1 - 1.8e-25 89.9 24.7 2.3e-25 89.5 24.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KEY64473.1 - 4.8e-06 26.0 25.4 1.4e-05 24.5 25.4 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEY64473.1 - 8.2e-05 22.8 39.0 0.0015 18.7 12.5 2.5 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_L27e PF01777.18 KEY64474.1 - 2.6e-36 123.8 1.9 4.1e-36 123.2 1.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KEY64474.1 - 0.0071 16.3 0.9 0.02 14.9 0.9 1.8 1 0 0 1 1 1 1 KOW motif DUF3666 PF12408.8 KEY64474.1 - 0.1 11.8 0.4 0.18 11.0 0.1 1.6 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase TPR_17 PF13431.6 KEY64475.1 - 0.012 16.0 0.3 0.096 13.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat KH_1 PF00013.29 KEY64475.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 KH domain Glyoxalase PF00903.25 KEY64476.1 - 3.5e-22 79.0 0.0 2.1e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEY64476.1 - 1.5e-09 38.1 0.0 0.0006 20.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KEY64476.1 - 0.0032 17.6 0.0 0.49 10.5 0.0 3.1 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KEY64476.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.14 KEY64477.1 - 1.4e-75 253.3 0.0 1.9e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KEY64477.1 - 4.8e-18 65.1 8.5 4.8e-18 65.1 8.5 2.7 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KEY64477.1 - 1e-16 61.5 0.0 2.8e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KEY64477.1 - 0.00038 20.8 0.0 0.00052 20.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Chs7 PF12271.8 KEY64478.1 - 4.6e-112 374.1 3.6 5.2e-112 373.9 3.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Sugar_tr PF00083.24 KEY64479.1 - 5.4e-107 358.5 12.8 6.6e-107 358.2 12.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64479.1 - 4.9e-29 101.4 43.9 2.1e-27 96.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY64479.1 - 1.9e-06 26.7 17.8 0.00013 20.7 3.1 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KEY64479.1 - 0.002 17.1 5.2 0.34 9.7 1.1 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KEY64479.1 - 0.19 10.1 4.2 0.18 10.2 0.4 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector TB2_DP1_HVA22 PF03134.19 KEY64479.1 - 0.51 10.3 5.3 0.16 11.9 1.7 2.0 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Complex1_LYR PF05347.15 KEY64480.1 - 0.0094 16.0 0.2 0.0094 16.0 0.2 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY64480.1 - 0.028 15.2 0.5 0.041 14.6 0.5 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Tho1_MOS11_C PF18592.1 KEY64480.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Frataxin_Cyay PF01491.16 KEY64481.1 - 1.3e-36 125.0 0.0 1.6e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro38C2 PF17677.1 KEY64481.1 - 0.081 13.0 0.1 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MetallophosN PF16371.5 KEY64481.1 - 0.14 12.5 0.2 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Clat_adaptor_s PF01217.20 KEY64482.1 - 1.7e-43 148.0 0.0 3.3e-43 147.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1 PF00133.22 KEY64484.1 - 1.3e-38 132.7 0.0 3e-28 98.5 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEY64484.1 - 4.2e-14 52.1 0.1 2.9e-09 36.2 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEY64484.1 - 4e-11 43.1 4.0 4e-11 43.1 2.1 2.0 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEY64484.1 - 2.8e-07 30.2 0.0 5.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CSL PF05207.13 KEY64486.1 - 1.9e-23 81.9 0.7 2.6e-23 81.5 0.7 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KEY64486.1 - 0.0013 18.8 0.4 0.002 18.2 0.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 KEY64486.1 - 0.37 10.8 3.3 0.77 9.7 3.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.15 KEY64487.1 - 2.4e-101 338.7 1.8 3.6e-101 338.1 1.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEY64487.1 - 1.1e-17 64.8 0.0 2.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEY64487.1 - 0.00028 20.8 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY64487.1 - 0.024 15.1 0.2 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KEY64487.1 - 0.083 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY64487.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KEY64487.1 - 0.13 11.6 0.1 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KEY64487.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KEY64487.1 - 0.24 11.7 3.3 0.33 11.3 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain IBR PF01485.21 KEY64488.1 - 1.8e-10 40.8 1.7 1.8e-10 40.8 1.7 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KEY64488.1 - 0.042 13.7 16.2 0.082 12.8 3.0 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 KEY64488.1 - 0.42 10.7 6.7 12 6.1 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Cytochrom_C_2 PF01322.20 KEY64488.1 - 0.57 11.1 8.1 0.98 10.3 7.0 1.9 2 0 0 2 2 2 0 Cytochrome C' DNA_RNApol_7kD PF03604.13 KEY64488.1 - 0.95 9.2 3.5 4.5 7.0 0.7 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 KEY64488.1 - 1.6 8.3 5.7 5.1 6.6 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain rRNA_processing PF08524.11 KEY64488.1 - 2.6 8.1 14.2 5.3 7.0 14.2 1.4 1 0 0 1 1 1 0 rRNA processing CDC45 PF02724.14 KEY64488.1 - 9.5 4.4 9.3 63 1.6 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein Jnk-SapK_ap_N PF09744.9 KEY64489.1 - 0.0004 20.7 2.6 0.00074 19.8 2.6 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 SIKE PF05769.11 KEY64489.1 - 0.0013 18.7 2.9 0.0023 17.9 2.9 1.3 1 0 0 1 1 1 1 SIKE family SHE3 PF17078.5 KEY64489.1 - 0.021 14.6 0.8 0.076 12.7 0.8 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 KEY64489.1 - 0.052 13.6 4.1 0.1 12.7 4.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 KEY64489.1 - 0.68 10.4 2.6 3.8 8.0 0.3 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF2968 PF11180.8 KEY64489.1 - 0.9 9.1 5.3 1.5 8.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ZapB PF06005.12 KEY64489.1 - 3.3 8.2 7.7 22 5.6 7.7 2.2 1 1 0 1 1 1 0 Cell division protein ZapB HSP70 PF00012.20 KEY64490.1 - 6.6e-13 47.7 0.0 1.1e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FGGY_C PF02782.16 KEY64490.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KEY64490.1 - 0.17 11.3 0.9 0.35 10.3 0.0 1.9 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family NTP_transf_7 PF07984.12 KEY64490.1 - 0.21 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase DOCK_N PF16172.5 KEY64491.1 - 3.1e-119 398.3 0.0 4.6e-119 397.7 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KEY64491.1 - 1.4e-33 116.4 0.0 3.2e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KEY64491.1 - 1.6e-33 116.2 0.3 6.3e-33 114.2 0.3 1.9 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 KEY64491.1 - 8.5e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY64491.1 - 0.00032 20.5 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KEY64491.1 - 0.18 11.5 0.0 0.55 9.9 0.0 1.9 1 1 0 1 1 1 0 Variant SH3 domain Acetyltransf_1 PF00583.25 KEY64492.1 - 0.0003 21.0 0.0 0.00069 19.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KEY64492.1 - 0.0019 18.8 0.1 0.15 12.8 0.1 2.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY64492.1 - 0.0096 15.9 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY64492.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S7 PF00177.21 KEY64493.1 - 2.7e-37 127.7 2.1 3.5e-37 127.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.15 KEY64494.1 - 1.1e-38 131.5 4.5 1.2e-38 131.4 4.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KEY64494.1 - 0.003 17.1 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KEY64494.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF1744 PF08490.12 KEY64494.1 - 0.036 12.6 0.0 0.038 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) HTH_11 PF08279.12 KEY64494.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 HTH domain Mito_carr PF00153.27 KEY64495.1 - 5.4e-66 218.6 4.6 6.6e-24 83.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KEY64495.1 - 0.043 13.6 1.3 0.18 11.6 1.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) CENP-X PF09415.10 KEY64496.1 - 3.6e-24 84.9 0.1 7.1e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X AT_hook PF02178.19 KEY64496.1 - 0.022 14.6 2.6 0.043 13.7 2.6 1.5 1 0 0 1 1 1 0 AT hook motif IATP PF04568.12 KEY64498.1 - 0.42 11.1 1.9 0.64 10.5 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Cyt-b5 PF00173.28 KEY64499.1 - 9.5e-11 41.7 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RAMP4 PF06624.12 KEY64499.1 - 0.073 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 BTB_2 PF02214.22 KEY64501.1 - 1.8e-06 28.2 0.0 0.0013 19.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Rep_fac_C PF08542.11 KEY64502.1 - 7.7e-16 58.3 0.3 2.3e-15 56.8 0.1 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KEY64502.1 - 2.6e-15 57.0 0.0 5.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KEY64502.1 - 6.2e-12 45.6 0.2 4e-11 43.0 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KEY64502.1 - 5e-08 33.1 0.0 8.7e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KEY64502.1 - 2.1e-06 28.0 0.0 6.6e-06 26.4 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KEY64502.1 - 7e-06 26.0 0.1 0.00019 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY64502.1 - 1.9e-05 24.5 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY64502.1 - 3.7e-05 24.2 0.1 0.0018 18.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.13 KEY64502.1 - 4.9e-05 23.2 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KEY64502.1 - 9.6e-05 22.7 0.0 0.00085 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEY64502.1 - 0.00011 22.0 0.0 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEY64502.1 - 0.00046 20.2 0.1 0.0017 18.4 0.1 2.0 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEY64502.1 - 0.00077 19.3 0.3 0.0047 16.8 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KEY64502.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEY64502.1 - 0.0049 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY64502.1 - 0.006 16.9 0.8 0.013 15.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEY64502.1 - 0.008 15.6 0.1 0.052 12.9 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KEY64502.1 - 0.011 15.8 0.0 0.09 12.8 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KEY64502.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY64502.1 - 0.014 15.9 0.0 0.043 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KEY64502.1 - 0.017 14.6 0.5 3.4 7.1 0.0 2.4 1 1 1 2 2 2 0 PhoH-like protein TniB PF05621.11 KEY64502.1 - 0.029 13.8 0.0 0.26 10.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 KEY64502.1 - 0.041 13.4 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 KEY64502.1 - 0.056 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DEAD PF00270.29 KEY64502.1 - 0.12 12.1 0.4 0.86 9.3 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KEY64502.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase PAP2 PF01569.21 KEY64503.1 - 2e-17 63.2 3.8 6.5e-17 61.6 3.8 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KEY64503.1 - 0.0066 16.2 5.4 0.016 14.9 5.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily adh_short_C2 PF13561.6 KEY64504.1 - 9.3e-44 149.7 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY64504.1 - 6.1e-39 133.5 0.0 8.1e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY64504.1 - 7.9e-11 42.2 0.4 1.2e-10 41.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY64504.1 - 6.2e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY64504.1 - 0.0019 17.4 0.1 0.0023 17.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KEY64504.1 - 0.022 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KEY64504.1 - 0.042 13.7 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 KEY64504.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ThiF PF00899.21 KEY64505.1 - 3.9e-74 249.1 0.0 5.2e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KEY64505.1 - 7.3e-20 71.4 2.2 1.7e-19 70.2 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KEY64505.1 - 9.1e-07 29.0 1.1 0.0013 18.8 0.0 2.9 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KEY64505.1 - 0.00097 19.5 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KEY64505.1 - 0.0038 17.7 0.1 1.7 9.2 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEY64505.1 - 0.0046 17.0 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEY64505.1 - 0.12 12.6 0.3 0.48 10.7 0.3 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_34 PF05637.12 KEY64506.1 - 2e-63 214.3 0.2 2.7e-63 213.9 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MAPEG PF01124.18 KEY64506.1 - 1.9e-12 47.2 0.5 1.9e-12 47.2 0.5 2.1 2 0 0 2 2 2 1 MAPEG family Peptidase_M22 PF00814.25 KEY64507.1 - 4.9e-47 160.9 0.4 2.1e-26 93.2 1.3 2.7 1 1 1 2 2 2 2 Glycoprotease family MutL_C PF08676.11 KEY64508.1 - 1.3e-22 80.2 0.0 2.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KEY64508.1 - 5.8e-18 64.7 0.0 2.1e-17 62.9 0.0 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEY64508.1 - 2.9e-12 46.6 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEY64508.1 - 3.9e-06 27.3 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4703 PF15775.5 KEY64508.1 - 5.3 6.8 6.7 4.3 7.1 3.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4703) Pyr_redox_2 PF07992.14 KEY64510.1 - 4.1e-10 39.4 0.0 7.3e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY64510.1 - 0.008 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Asp_Glu_race PF01177.22 KEY64510.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase TetR_C_5 PF08360.11 KEY64510.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region ETF PF01012.21 KEY64511.1 - 1.7e-45 155.1 2.2 2.7e-45 154.5 2.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KEY64511.1 - 1.8e-33 114.4 0.3 3.7e-33 113.4 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 KEY64512.1 - 4.8e-32 110.2 0.1 1e-31 109.1 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KEY64512.1 - 4.1e-31 106.8 3.1 8.8e-31 105.7 3.1 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KEY64512.1 - 1e-08 35.2 0.0 2.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY64512.1 - 3.9e-05 23.8 0.1 8.7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KEY64512.1 - 0.00015 21.5 5.1 0.00031 20.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SANT_DAMP1_like PF16282.5 KEY64512.1 - 0.046 13.9 0.1 0.09 13.0 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Carn_acyltransf PF00755.20 KEY64513.1 - 6.9e-212 705.2 0.0 7.8e-212 705.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.19 KEY64514.1 - 1.1e-121 406.2 0.1 1.6e-121 405.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KEY64514.1 - 2.4e-54 183.2 1.3 3.2e-54 182.8 1.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.19 KEY64514.1 - 0.031 14.9 3.8 8.9 7.0 0.7 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein TBCC PF07986.12 KEY64514.1 - 0.11 12.2 0.7 0.41 10.4 0.5 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.24 KEY64515.1 - 9.5e-15 54.7 0.0 9.4e-09 35.0 0.5 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 KEY64516.1 - 2.6e-97 324.3 0.1 4.4e-97 323.6 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEY64516.1 - 5.2e-32 110.3 0.1 9.8e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEY64516.1 - 3.2e-24 85.2 0.6 6.8e-24 84.1 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY64516.1 - 8.9e-12 45.5 0.0 2.8e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEY64516.1 - 4.8e-07 29.4 0.0 5.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEY64516.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEY64516.1 - 0.017 14.9 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Apt1 PF10351.9 KEY64516.1 - 9.8 4.9 11.9 16 4.2 11.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 KEY64516.1 - 9.9 5.7 12.5 18 4.8 12.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exo70 PF03081.15 KEY64517.1 - 1.1e-87 294.6 0.0 2.2e-87 293.6 0.0 1.5 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 KEY64517.1 - 0.011 15.8 9.9 1.5 8.8 0.9 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipo_F PF15148.6 KEY64517.1 - 0.09 12.3 0.4 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein F Apolipoprotein PF01442.18 KEY64517.1 - 1.2 8.9 13.0 0.15 11.9 0.6 3.6 3 2 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF2203 PF09969.9 KEY64517.1 - 4 8.2 8.0 3.2 8.5 0.1 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Nnf1 PF03980.14 KEY64517.1 - 4.4 7.7 9.6 0.33 11.4 1.4 3.1 3 1 0 3 3 3 0 Nnf1 ADH_N PF08240.12 KEY64518.1 - 1.7e-23 82.6 4.8 2.7e-23 81.9 4.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY64518.1 - 2.9e-18 66.1 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY64518.1 - 2.5e-05 25.3 0.0 3.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEY64518.1 - 0.0055 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEY64518.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3744 PF12558.8 KEY64518.1 - 0.18 12.6 0.0 0.31 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter EHN PF06441.12 KEY64519.1 - 7.4e-35 119.6 2.6 6.7e-34 116.5 0.2 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEY64519.1 - 3.4e-12 46.6 0.0 2.8e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY64519.1 - 0.33 11.5 2.7 1 9.9 2.7 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 KEY64520.1 - 5.5e-05 22.2 0.4 6.3e-05 22.0 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64520.1 - 0.00069 19.7 4.0 0.0011 19.0 4.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KEY64521.1 - 5.1e-06 26.5 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KEY64521.1 - 0.034 14.3 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KEY64521.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY64521.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Torus PF16131.5 KEY64522.1 - 0.00032 21.4 0.7 0.069 13.9 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KEY64522.1 - 0.0013 18.6 16.5 0.0075 16.2 1.1 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEY64522.1 - 0.0042 16.9 2.0 0.0042 16.9 2.0 3.4 5 0 0 5 5 5 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEY64522.1 - 0.026 14.6 5.3 0.026 14.6 5.3 3.6 3 0 0 3 3 3 0 Zinc finger domain EthD PF07110.11 KEY64523.1 - 0.068 14.3 0.1 0.28 12.4 0.1 1.8 1 1 0 1 1 1 0 EthD domain Ring_hydroxyl_A PF00848.19 KEY64524.1 - 2.4e-23 83.2 6.1 6.2e-11 42.7 4.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KEY64524.1 - 5.5e-16 58.3 0.0 1.2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CorC_HlyC PF03471.17 KEY64524.1 - 0.014 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain DAO PF01266.24 KEY64525.1 - 4.4e-30 105.5 0.1 6.8e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 KEY64525.1 - 3.4e-08 32.8 0.7 5.3e-08 32.2 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_9 PF13454.6 KEY64525.1 - 1.6e-07 31.4 0.1 0.0085 16.1 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KEY64525.1 - 5.7e-05 22.1 0.0 0.00084 18.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 KEY64525.1 - 0.0012 18.0 0.1 0.0036 16.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KEY64525.1 - 0.0013 18.0 0.1 0.73 9.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY64525.1 - 0.0057 16.9 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY64525.1 - 0.17 11.1 0.0 18 4.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GCV_T PF01571.21 KEY64526.1 - 2.7e-59 200.6 0.0 3.8e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KEY64526.1 - 2.6e-42 145.7 0.3 4.1e-42 145.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KEY64526.1 - 2.2e-16 59.9 0.0 4.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KEY64526.1 - 6.1e-16 58.1 0.0 1.7e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.27 KEY64526.1 - 4.3e-05 24.0 1.0 0.01 16.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY64526.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY64526.1 - 0.00016 21.0 0.1 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KEY64526.1 - 0.0044 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KEY64526.1 - 0.0069 16.6 0.6 0.034 14.4 0.3 2.2 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 KEY64526.1 - 0.023 13.4 0.4 0.37 9.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KEY64526.1 - 0.025 14.6 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KEY64526.1 - 0.027 14.7 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEY64526.1 - 0.027 14.4 0.5 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEY64526.1 - 0.052 12.8 0.2 0.21 10.8 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KEY64526.1 - 0.065 13.4 0.0 1 9.5 0.0 2.5 1 1 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Trp_halogenase PF04820.14 KEY64526.1 - 0.08 11.8 1.2 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M20 PF01546.28 KEY64527.1 - 7.4e-08 32.3 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY64527.1 - 1.1e-05 25.3 0.2 2.4e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain FCD PF07729.12 KEY64527.1 - 0.0087 16.5 0.0 0.36 11.3 0.1 2.4 1 1 1 2 2 2 1 FCD domain YbfN PF13982.6 KEY64528.1 - 0.0085 16.4 0.4 0.015 15.5 0.4 1.4 1 0 0 1 1 1 1 YbfN-like lipoprotein 2OG-FeII_Oxy PF03171.20 KEY64529.1 - 1.2e-13 51.4 0.0 2.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KEY64529.1 - 2.6e-10 41.1 0.0 4.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_1 PF00561.20 KEY64530.1 - 8.2e-18 65.0 0.2 1.1e-16 61.3 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KEY64530.1 - 5.1e-06 26.5 0.0 3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KEY64530.1 - 0.0017 17.6 0.0 0.0058 15.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY64530.1 - 0.0041 15.9 0.0 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 Ndr family Fungal_trans_2 PF11951.8 KEY64531.1 - 4.6e-05 22.4 0.4 0.00033 19.6 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64531.1 - 0.0022 18.1 2.9 0.0022 18.1 2.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1c PF00749.21 KEY64532.1 - 1.3e-96 323.3 0.0 2.9e-96 322.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEY64532.1 - 9.9e-34 116.7 0.0 1.1e-32 113.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fungal_trans PF04082.18 KEY64533.1 - 0.00049 19.2 0.1 0.0031 16.6 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 KEY64534.1 - 1.6e-34 119.5 43.7 2.1e-34 119.1 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY64534.1 - 7e-13 48.0 32.8 9.6e-13 47.5 32.8 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.13 KEY64534.1 - 0.0015 16.8 0.4 0.0024 16.1 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) Ndc1_Nup PF09531.10 KEY64534.1 - 7.8 5.1 12.9 13 4.3 12.9 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 KEY64535.1 - 1.7e-23 83.2 34.9 4.7e-23 81.7 34.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.16 KEY64536.1 - 8.4e-05 22.6 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MatE PF01554.18 KEY64537.1 - 6e-50 169.0 31.3 9.4e-31 106.6 10.1 2.4 2 0 0 2 2 2 2 MatE Arginase PF00491.21 KEY64538.1 - 1.9e-81 273.6 0.1 2.4e-81 273.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family Ribonuc_L-PSP PF01042.21 KEY64539.1 - 3.5e-17 62.5 0.0 3e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.22 KEY64540.1 - 9.2e-54 182.9 0.0 1.3e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEY64541.1 - 1.2e-34 119.9 25.8 1.2e-34 119.9 25.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily RhodobacterPufX PF11511.8 KEY64541.1 - 0.048 13.3 2.0 7.5 6.2 0.1 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Fungal_trans PF04082.18 KEY64542.1 - 1.1e-21 77.0 0.0 2.2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64542.1 - 0.00061 19.9 7.0 0.0013 18.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.17 KEY64543.1 - 1.6e-35 122.6 0.2 2.5e-35 122.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY64543.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Oxidored_FMN PF00724.20 KEY64544.1 - 2.9e-89 299.7 0.0 3.4e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 KEY64545.1 - 2.1e-44 151.9 51.5 3.6e-43 147.9 51.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY64545.1 - 7.9e-18 64.2 16.0 8.6e-18 64.1 15.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEY64545.1 - 6.6e-14 51.6 10.0 6.6e-14 51.6 10.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KEY64545.1 - 0.4 8.9 14.4 0.1 10.9 4.1 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Polysacc_deac_1 PF01522.21 KEY64546.1 - 1.9e-13 50.4 0.0 3.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 KEY64547.1 - 8.5e-27 93.8 0.1 2e-26 92.6 0.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Sugarporin_N PF11471.8 KEY64547.1 - 0.016 15.1 0.4 0.039 13.9 0.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Transp_cyt_pur PF02133.15 KEY64548.1 - 1e-82 278.3 37.7 1.4e-82 277.9 37.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 KEY64548.1 - 1.9e-66 224.9 0.3 3.9e-66 223.9 0.3 1.5 1 1 0 1 1 1 1 Amidase Sugar_tr PF00083.24 KEY64549.1 - 9.6e-70 235.7 23.0 1.1e-69 235.5 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64549.1 - 4.1e-07 29.3 17.0 4.1e-07 29.3 17.0 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily Raffinose_syn PF05691.12 KEY64550.1 - 6.4e-53 179.7 0.0 1.2e-39 135.8 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 adh_short PF00106.25 KEY64551.1 - 6.2e-11 42.1 0.0 1.1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64551.1 - 6.8e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64551.1 - 0.0019 18.1 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KEY64552.1 - 2.5e-11 43.1 0.0 4.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY64553.1 - 1.1e-20 73.9 0.3 4e-20 72.1 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 KEY64553.1 - 2.8e-09 37.1 0.0 4.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY64553.1 - 7e-09 35.6 0.1 1e-07 31.8 0.0 2.4 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY64553.1 - 0.00011 21.8 0.0 0.00031 20.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY64553.1 - 0.0053 16.0 0.1 0.0079 15.4 0.1 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KEY64553.1 - 0.0071 15.5 0.1 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KEY64553.1 - 0.037 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEY64553.1 - 0.077 12.9 0.2 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEY64553.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEY64553.1 - 0.17 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Turandot PF07240.11 KEY64553.1 - 0.18 11.8 0.2 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot NAD_binding_10 PF13460.6 KEY64554.1 - 2.1e-14 53.8 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding LpxI_N PF17930.1 KEY64554.1 - 0.19 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 LpxI N-terminal domain Gin PF10764.9 KEY64555.1 - 0.035 14.1 0.4 0.057 13.4 0.4 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin HET PF06985.11 KEY64556.1 - 4.9e-28 98.3 0.0 8.1e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KEY64557.1 - 5.5e-12 45.3 1.7 5.7e-12 45.2 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AnmK PF03702.14 KEY64558.1 - 3.3e-76 256.8 0.1 1.2e-58 199.0 0.6 2.0 1 1 1 2 2 2 2 Anhydro-N-acetylmuramic acid kinase Sugar_tr PF00083.24 KEY64560.1 - 4.8e-79 266.3 25.8 5.4e-79 266.1 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64560.1 - 7.3e-18 64.6 24.0 7.3e-18 64.6 24.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ComP_DUS PF16732.5 KEY64560.1 - 0.15 12.9 0.3 0.28 12.1 0.3 1.4 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor RBP_receptor PF14752.6 KEY64560.1 - 0.2 10.2 10.3 0.024 13.2 2.0 2.1 2 0 0 2 2 2 0 Retinol binding protein receptor DUF1304 PF06993.12 KEY64560.1 - 1.5 8.9 9.4 0.12 12.4 0.8 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1304) TAL_FSA PF00923.19 KEY64561.1 - 1.1e-73 248.2 1.2 1.2e-73 247.9 1.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GAF_3 PF13492.6 KEY64561.1 - 0.036 14.4 0.7 0.56 10.6 0.1 2.7 2 1 1 3 3 3 0 GAF domain Ebola_NP PF05505.12 KEY64561.1 - 0.14 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2694 PF10904.8 KEY64561.1 - 0.45 10.6 2.2 3 8.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2694) DAO PF01266.24 KEY64563.1 - 5.9e-40 137.9 3.7 6.7e-40 137.7 3.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY64563.1 - 2e-05 24.7 1.8 0.048 13.7 0.6 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEY64563.1 - 2.3e-05 23.8 1.4 0.0003 20.1 1.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY64563.1 - 0.00021 20.5 2.8 0.13 11.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEY64563.1 - 0.00021 20.5 0.9 0.023 13.8 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KEY64563.1 - 0.0003 20.1 1.8 0.0066 15.7 0.3 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KEY64563.1 - 0.00056 19.1 1.4 0.031 13.3 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY64563.1 - 0.00067 19.8 1.4 0.00077 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KEY64563.1 - 0.039 13.6 1.0 0.087 12.5 1.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEY64563.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEY64563.1 - 0.092 13.0 0.5 0.21 11.8 0.5 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GARS_N PF02844.15 KEY64563.1 - 0.13 13.1 0.0 0.5 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain FAD_binding_3 PF01494.19 KEY64563.1 - 0.26 10.5 3.0 2.6 7.2 0.4 2.3 2 1 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KEY64563.1 - 0.33 9.8 7.1 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DinB_2 PF12867.7 KEY64563.1 - 0.84 10.1 5.0 1 9.9 3.1 2.1 2 1 0 2 2 2 0 DinB superfamily Glyco_hydro_18 PF00704.28 KEY64565.1 - 2.5e-68 231.1 0.0 5.6e-68 230.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY64565.1 - 1.7e-13 50.8 16.1 1.7e-13 50.8 16.1 4.6 4 1 0 4 4 4 2 Chitin recognition protein PRMT5_TIM PF17285.2 KEY64565.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 TIM barrel domain LysM PF01476.20 KEY64566.1 - 2.7e-21 75.3 0.1 1.2e-05 25.2 0.1 5.0 5 0 0 5 5 5 4 LysM domain DUF202 PF02656.15 KEY64567.1 - 7.5e-20 71.2 0.1 2.7e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glyco_transf_54 PF04666.13 KEY64568.1 - 1.3e-14 53.7 0.0 4.7e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CBM_1 PF00734.18 KEY64569.1 - 5.6e-11 42.2 15.5 5.6e-11 42.2 15.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KEY64569.1 - 0.00046 19.7 0.5 0.00095 18.7 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEY64569.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KEY64569.1 - 0.1 12.2 1.4 0.36 10.4 1.4 2.0 1 1 0 1 1 1 0 Putative esterase Toxin_7 PF05980.12 KEY64569.1 - 1.1 9.6 12.8 0.33 11.2 8.6 2.2 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_18 PF00704.28 KEY64570.1 - 9.3e-83 278.5 1.2 1.1e-82 278.3 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MANEC PF07502.14 KEY64571.1 - 8.6e-06 25.9 2.1 0.098 12.9 0.0 2.6 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 KEY64571.1 - 0.0079 16.1 13.7 0.082 12.8 0.4 3.1 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.12 KEY64571.1 - 6.5 6.7 15.5 2.9 7.8 0.1 3.8 3 1 0 3 3 3 0 PAN-like domain p450 PF00067.22 KEY64572.1 - 3.8e-52 177.6 0.0 5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.9 KEY64573.1 - 1.1e-23 83.9 0.2 1.7e-23 83.3 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEY64573.1 - 5.3e-12 45.7 0.1 8.7e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KEY64573.1 - 3.9e-11 42.7 12.1 3.9e-11 42.7 12.1 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_2 PF02230.16 KEY64573.1 - 0.0017 18.2 0.4 0.0095 15.8 0.4 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KEY64573.1 - 0.003 17.2 0.8 0.023 14.4 0.8 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KEY64573.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Toxin_7 PF05980.12 KEY64573.1 - 0.023 14.9 8.3 0.023 14.9 8.3 2.1 2 0 0 2 2 2 0 Toxin 7 Hydrolase_4 PF12146.8 KEY64573.1 - 0.042 13.1 0.1 0.14 11.4 0.2 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KEY64573.1 - 0.11 12.0 1.3 0.21 11.1 1.2 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Alpha-amylase PF00128.24 KEY64575.1 - 4.8e-108 361.7 0.3 8.9e-108 360.8 0.3 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KEY64575.1 - 0.0051 16.0 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KEY64575.1 - 0.034 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Glyco_hydro_32N PF00251.20 KEY64576.1 - 7.5e-45 153.8 0.0 1.1e-44 153.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY64576.1 - 9.9e-07 28.9 0.2 1.9e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 KEY64576.1 - 0.0054 16.1 0.2 2.1 7.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 BNR PF02012.20 KEY64576.1 - 0.015 15.2 0.9 0.3 11.2 0.1 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF4185 PF13810.6 KEY64576.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) BNR_6 PF15899.5 KEY64576.1 - 0.19 11.9 6.4 18 5.8 0.2 3.9 3 0 0 3 3 3 0 BNR-Asp box repeat Sugar_tr PF00083.24 KEY64577.1 - 1.5e-72 244.9 20.6 1.8e-72 244.6 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64577.1 - 2.1e-19 69.7 37.3 4e-18 65.5 30.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Zn_clus PF00172.18 KEY64578.1 - 9.8e-08 32.0 7.2 1.7e-07 31.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY64578.1 - 8e-06 25.1 0.3 1.6e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3810 PF12725.7 KEY64579.1 - 0.0042 16.5 0.3 0.015 14.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) PHBC_N PF12551.8 KEY64579.1 - 0.95 9.3 9.6 8.4 6.3 0.8 3.3 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal FAD_binding_4 PF01565.23 KEY64581.1 - 3.2e-06 26.9 0.0 6.4e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KEY64584.1 - 1.4e-42 146.0 36.3 1.4e-42 146.0 36.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY64584.1 - 1.4e-13 50.6 4.8 1.4e-13 50.6 4.8 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KEY64584.1 - 0.71 8.1 16.5 0.021 13.2 1.3 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KEY64584.1 - 5.5 5.3 11.4 0.24 9.7 3.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Fungal_trans_2 PF11951.8 KEY64585.1 - 0.0044 15.9 0.0 0.0097 14.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY64586.1 - 2.5e-23 82.6 0.0 3.4e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY64586.1 - 3.8e-08 33.4 0.1 6.1e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY64586.1 - 7.4e-07 29.0 0.0 1.9e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Myb_DNA-binding PF00249.31 KEY64587.1 - 1.2e-24 86.2 1.0 2.6e-13 49.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY64587.1 - 4.3e-19 68.5 1.8 3.6e-09 36.7 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KEY64587.1 - 0.00048 20.0 0.5 0.048 13.5 0.0 2.5 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KEY64587.1 - 0.018 15.2 0.0 5.5 7.3 0.0 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 CDK5_activator PF03261.15 KEY64587.1 - 0.036 13.6 1.3 0.042 13.4 1.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SLIDE PF09111.10 KEY64587.1 - 0.076 13.0 0.0 9.3 6.3 0.0 2.4 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 KEY64587.1 - 0.27 11.6 2.4 7.1 7.1 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.12 KEY64587.1 - 0.68 9.2 4.9 0.99 8.7 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 KEY64588.1 - 6.5e-54 183.4 0.0 9.9e-52 176.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KEY64589.1 - 1.3e-77 260.8 0.2 6.9e-77 258.4 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY64589.1 - 2.5e-29 101.7 2.0 2.1e-19 69.7 0.0 3.0 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KEY64589.1 - 5.7e-27 93.4 0.0 2e-26 91.7 0.0 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KEY64589.1 - 1.9e-21 76.9 0.0 9e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KEY64589.1 - 3.1e-20 72.6 0.0 5.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KEY64589.1 - 3e-17 63.2 0.0 1e-16 61.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KEY64589.1 - 1.3e-15 57.8 2.7 1.7e-11 44.4 0.1 3.9 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 KEY64589.1 - 4.8e-14 52.5 0.0 2.2e-12 47.1 0.0 3.5 5 0 0 5 5 4 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KEY64589.1 - 6.5e-13 49.0 0.0 3.2e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KEY64589.1 - 3.4e-11 43.7 0.0 2.6e-10 40.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KEY64589.1 - 1.1e-09 38.5 0.8 2.3e-09 37.5 0.8 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KEY64589.1 - 7.5e-09 36.1 0.0 4.5e-08 33.6 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY64589.1 - 1e-07 31.9 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY64589.1 - 1.1e-07 32.3 0.0 3.8e-07 30.6 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY64589.1 - 1.2e-06 28.1 0.2 4.1e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Peptidase_S9 PF00326.21 KEY64589.1 - 0.00016 21.3 0.0 0.029 13.8 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY64589.1 - 0.0011 19.6 3.2 0.012 16.2 0.9 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 KEY64589.1 - 0.0045 16.4 0.0 0.04 13.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEY64589.1 - 0.0064 16.2 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 KEY64589.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 KEY64589.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Lactamase_B PF00753.27 KEY64590.1 - 1.3e-11 44.9 0.4 2.8e-11 43.8 0.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY64590.1 - 2e-05 24.2 0.1 4.3e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Trp_DMAT PF11991.8 KEY64591.1 - 5.6e-79 266.2 0.0 7e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase RNA_POL_M_15KD PF02150.16 KEY64591.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Methyltransf_2 PF00891.18 KEY64592.1 - 3.3e-21 75.6 0.0 4.6e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KEY64592.1 - 0.0021 18.0 0.2 0.0072 16.3 0.1 2.0 2 0 0 2 2 2 1 Dimerisation domain p450 PF00067.22 KEY64593.1 - 1.8e-43 149.0 0.0 2.4e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KEY64593.1 - 0.09 12.5 0.7 0.23 11.2 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) GMC_oxred_N PF00732.19 KEY64594.1 - 3.3e-53 181.0 0.0 4.3e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY64594.1 - 5.4e-26 91.8 0.0 1.4e-25 90.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase p450 PF00067.22 KEY64594.1 - 2.6e-09 36.4 0.0 3.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_2 PF00890.24 KEY64594.1 - 3.2e-07 29.8 1.9 6.9e-06 25.4 1.9 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY64594.1 - 8.7e-06 25.2 0.0 0.005 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY64594.1 - 4.5e-05 23.2 2.0 0.00025 20.8 1.5 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY64594.1 - 0.00016 21.9 0.1 0.00047 20.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY64594.1 - 0.00023 20.4 0.1 0.00048 19.3 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY64594.1 - 0.0011 18.2 0.1 0.0029 16.9 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY64594.1 - 0.0012 18.2 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 KEY64594.1 - 0.061 12.2 0.2 0.089 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KEY64594.1 - 0.075 13.0 0.6 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY64594.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KEY64594.1 - 0.17 12.2 0.3 0.4 11.0 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KEY64594.1 - 0.25 11.9 0.5 1.1 9.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Condensation PF00668.20 KEY64595.1 - 0 1333.4 18.7 6.5e-94 315.2 2.7 5.5 5 0 0 5 5 5 5 Condensation domain AMP-binding PF00501.28 KEY64595.1 - 0 1208.9 0.0 7.2e-78 262.1 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 KEY64595.1 - 2e-65 217.1 6.9 1.6e-12 47.6 0.0 6.6 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEY64595.1 - 6e-41 139.3 4.5 8.3e-05 23.5 0.0 9.9 9 0 0 9 9 9 8 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.12 KEY64595.1 - 3.8e-29 101.3 0.4 8.1e-07 29.7 0.0 5.8 5 0 0 5 5 5 4 Methyltransferase domain Methyltransf_23 PF13489.6 KEY64595.1 - 3.8e-29 101.6 0.4 3.2e-06 27.1 0.0 5.8 7 0 0 7 7 7 4 Methyltransferase domain Methyltransf_25 PF13649.6 KEY64595.1 - 2.8e-28 98.4 0.0 7.4e-06 26.6 0.0 5.1 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64595.1 - 2.8e-25 88.8 0.0 1.2e-06 29.0 0.0 5.0 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_31 PF13847.6 KEY64595.1 - 6.1e-20 71.6 0.0 9.4e-05 22.3 0.0 4.8 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_16 PF10294.9 KEY64595.1 - 1.6e-08 34.5 0.4 0.34 10.6 0.0 4.5 4 0 0 4 4 4 3 Lysine methyltransferase Methyltransf_9 PF08003.11 KEY64595.1 - 6.5e-07 28.6 0.1 0.0033 16.4 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1698) Abhydrolase_6 PF12697.7 KEY64595.1 - 1.1e-06 29.4 2.6 6e-06 27.0 0.4 3.3 3 0 0 3 3 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KEY64595.1 - 2.7e-06 27.7 1.2 2e-05 24.8 0.0 3.2 3 0 0 3 3 3 1 Thioesterase domain Methyltransf_24 PF13578.6 KEY64595.1 - 4.1e-06 27.8 0.0 0.25 12.4 0.0 4.7 4 0 0 4 4 4 2 Methyltransferase domain PAC4 PF16093.5 KEY64595.1 - 0.0035 17.5 3.1 42 4.4 0.0 6.3 6 0 0 6 6 6 0 Proteasome assembly chaperone 4 MetW PF07021.12 KEY64595.1 - 0.0056 16.3 0.2 0.5 9.9 0.0 3.6 4 0 0 4 4 4 1 Methionine biosynthesis protein MetW Abhydrolase_1 PF00561.20 KEY64595.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Spore_YtrH PF14034.6 KEY64595.1 - 0.81 9.9 3.2 13 6.1 0.0 4.1 5 0 0 5 5 5 0 Sporulation protein YtrH Rad51 PF08423.11 KEY64596.1 - 5.9e-45 153.5 0.0 1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KEY64596.1 - 9e-10 38.4 0.2 2e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KEY64596.1 - 0.00016 21.2 0.1 0.0025 17.3 0.1 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KEY64596.1 - 0.0029 17.0 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KEY64596.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEY64596.1 - 0.068 13.1 0.1 0.3 11.0 0.1 1.9 1 1 0 1 1 1 0 NACHT domain RNA_pol_Rpb2_6 PF00562.28 KEY64597.1 - 1.4e-121 406.3 0.2 5.3e-121 404.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEY64597.1 - 1.6e-44 151.9 0.1 2.7e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KEY64597.1 - 1.6e-33 114.9 0.4 3.9e-33 113.7 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KEY64597.1 - 3.3e-28 98.6 0.1 7.4e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KEY64597.1 - 8.9e-22 77.2 0.1 2e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KEY64597.1 - 2.2e-20 72.6 0.0 4.7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEY64597.1 - 3.4e-10 40.3 1.4 1.1e-09 38.7 1.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Carn_acyltransf PF00755.20 KEY64598.1 - 5.6e-211 702.2 0.0 2.1e-210 700.3 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KEY64600.1 - 2.3e-19 69.5 57.8 7.8e-18 64.5 49.5 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP70 PF00012.20 KEY64602.1 - 3.2e-252 838.0 4.4 3.7e-252 837.9 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY64602.1 - 7.1e-17 61.2 0.0 1.2e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KEY64602.1 - 0.0086 15.8 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KEY64602.1 - 0.03 14.7 1.0 21 5.6 0.0 3.2 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 KEY64602.1 - 0.031 13.5 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 KEY64602.1 - 0.032 13.5 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Actin PF00022.19 KEY64602.1 - 0.12 11.0 2.3 0.46 9.0 0.0 2.3 2 1 1 3 3 3 0 Actin PMBR PF09373.10 KEY64602.1 - 1.2 9.4 3.9 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Pseudomurein-binding repeat GMC_oxred_N PF00732.19 KEY64603.1 - 0.00013 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase EVE PF01878.18 KEY64605.1 - 1.7e-47 161.0 0.1 2.9e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 EVE domain Trypan_PARP PF05887.11 KEY64605.1 - 0.046 13.7 6.9 0.086 12.8 6.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IDO PF01231.18 KEY64607.1 - 8e-149 496.1 0.0 9.1e-149 495.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KEY64607.1 - 0.042 12.6 0.0 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 KEY64608.1 - 1.3e-06 27.6 0.0 2.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEY64608.1 - 0.047 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEY64608.1 - 0.21 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Kinesin PF00225.23 KEY64610.1 - 7.8e-116 386.6 0.3 1.8e-115 385.5 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEY64610.1 - 6.9e-27 94.2 0.0 1.5e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Fungal_trans PF04082.18 KEY64610.1 - 1.5e-10 40.6 0.0 1.3e-09 37.5 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64610.1 - 1.2e-06 28.5 14.0 2.4e-06 27.5 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3584 PF12128.8 KEY64610.1 - 0.0018 15.9 3.5 0.0028 15.3 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Serglycin PF04360.12 KEY64610.1 - 0.0093 15.9 1.8 0.026 14.5 1.8 1.7 1 0 0 1 1 1 1 Serglycin MgrB PF13998.6 KEY64610.1 - 0.23 11.4 0.1 0.55 10.2 0.1 1.6 1 0 0 1 1 1 0 MgrB protein DUF2142 PF09913.9 KEY64610.1 - 0.47 9.3 2.0 0.86 8.4 2.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Herpes_UL14 PF03580.14 KEY64610.1 - 0.76 10.0 6.6 2.8 8.2 6.6 1.9 1 1 0 1 1 1 0 Herpesvirus UL14-like protein AAA_23 PF13476.6 KEY64610.1 - 2.7 8.4 4.4 0.88 10.0 0.8 1.9 2 0 0 2 2 2 0 AAA domain Glyco_hydro_115 PF15979.5 KEY64611.1 - 1.2e-135 452.3 0.1 1.7e-135 451.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEY64611.1 - 1e-43 149.2 0.0 1.6e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain zf-C2H2_4 PF13894.6 KEY64612.1 - 5.6e-08 33.0 2.1 0.0036 18.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY64612.1 - 1.1e-06 28.7 3.1 0.0063 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KEY64612.1 - 0.08 13.0 1.2 1.3 9.1 0.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger FTA2 PF13095.6 KEY64613.1 - 3.1e-54 183.9 0.0 5.6e-54 183.0 0.0 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 KEY64615.1 - 1.2e-42 145.6 0.3 1.7e-42 145.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64615.1 - 2.9e-40 138.3 0.1 4.3e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64615.1 - 5.1e-10 39.5 0.1 8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain PAF-AH_p_II PF03403.13 KEY64616.1 - 1.9e-07 30.0 0.1 0.0011 17.6 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KEY64616.1 - 1.1e-05 26.2 3.9 4.4e-05 24.2 2.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KEY64616.1 - 0.0004 19.4 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KEY64616.1 - 0.042 13.3 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KEY64616.1 - 0.058 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Vta1 PF04652.16 KEY64617.1 - 6.1e-49 165.7 2.4 3e-48 163.5 1.1 2.0 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KEY64617.1 - 3.1e-18 65.2 0.0 6.4e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain DUF2654 PF10849.8 KEY64617.1 - 0.038 14.2 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) F-box-like_2 PF13013.6 KEY64618.1 - 0.0092 15.9 0.3 0.068 13.2 0.2 2.1 2 0 0 2 2 2 1 F-box-like domain NIF PF03031.18 KEY64619.1 - 1.6e-37 128.7 0.0 2.2e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Tim17 PF02466.19 KEY64623.1 - 0.0026 18.1 5.6 0.0041 17.5 4.6 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Alk_phosphatase PF00245.20 KEY64624.1 - 2.2e-70 237.7 0.0 2.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Pro_dh PF01619.18 KEY64625.1 - 8.5e-69 232.3 0.0 1.1e-68 232.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase CGI-121 PF08617.10 KEY64626.1 - 1.8e-52 177.7 0.2 2.1e-52 177.5 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Zn_clus PF00172.18 KEY64627.1 - 1.8e-05 24.7 17.5 1.8e-05 24.7 17.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carb_anhydrase PF00194.21 KEY64628.1 - 2.9e-31 108.9 0.0 5.6e-31 108.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Big_9 PF17963.1 KEY64628.1 - 0.0069 17.1 0.9 0.0069 17.1 0.9 2.3 1 1 0 2 2 2 1 Bacterial Ig domain CA_like PF10563.9 KEY64628.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 Putative carbonic anhydrase Adenylsucc_synt PF00709.21 KEY64629.1 - 6.3e-06 25.4 0.0 6.3e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase HATPase_c PF02518.26 KEY64631.1 - 3.1e-20 72.7 0.0 7.7e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY64631.1 - 1.6e-16 60.5 0.0 7.8e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KEY64631.1 - 4.5e-12 45.8 1.3 1e-11 44.7 0.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KEY64631.1 - 0.0017 19.0 0.0 0.0093 16.6 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KEY64631.1 - 0.017 15.4 0.0 0.062 13.6 0.0 2.1 1 1 0 1 1 1 0 GAF domain HATPase_c_2 PF13581.6 KEY64631.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Methyltransf_PK PF05891.12 KEY64632.1 - 1e-75 254.0 0.0 1.2e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KEY64632.1 - 1e-06 29.4 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64632.1 - 1.2e-05 25.9 0.0 1.8e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY64632.1 - 0.0013 18.6 0.0 0.0045 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY64632.1 - 0.026 15.3 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KEY64632.1 - 0.19 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SET PF00856.28 KEY64633.1 - 9.1e-11 42.4 0.0 1.4e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Fibrinogen_C PF00147.18 KEY64633.1 - 0.14 12.0 0.1 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain Thioredoxin PF00085.20 KEY64636.1 - 7.2e-32 109.4 0.1 8.3e-25 86.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KEY64636.1 - 3.2e-08 33.7 0.0 8.1e-07 29.1 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KEY64636.1 - 4.7e-07 30.2 0.1 0.052 14.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEY64636.1 - 1.1e-05 24.9 0.0 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KEY64636.1 - 0.00027 21.2 0.0 3.8 7.9 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like HyaE PF07449.11 KEY64636.1 - 0.0016 18.4 0.0 0.95 9.4 0.1 3.4 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KEY64636.1 - 0.0022 18.1 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KEY64636.1 - 0.013 15.6 1.4 2.2 8.4 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin domain QSOX_Trx1 PF18108.1 KEY64636.1 - 0.016 15.4 0.0 0.058 13.6 0.0 1.9 2 0 0 2 2 2 0 QSOX Trx-like domain AhpC-TSA PF00578.21 KEY64636.1 - 0.032 14.2 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 KEY64636.1 - 0.15 11.9 0.0 0.15 11.9 0.0 4.0 3 1 1 4 4 3 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 KEY64636.1 - 0.22 11.8 0.3 42 4.5 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin CCDC53 PF10152.9 KEY64636.1 - 0.25 11.8 8.0 1 9.8 1.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RNase_PH PF01138.21 KEY64637.1 - 1.1e-34 119.8 0.4 1.7e-34 119.2 0.4 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_N PF08240.12 KEY64638.1 - 1.5e-27 95.6 0.8 4.1e-27 94.2 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY64638.1 - 1.1e-17 64.2 0.6 1.8e-17 63.5 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY64638.1 - 6.4e-07 30.5 0.0 1.3e-06 29.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 KEY64639.1 - 2e-22 79.4 0.2 3.5e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Peptidase_M3 PF01432.20 KEY64640.1 - 4.1e-100 336.2 0.0 5.1e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 BAG6 PF12057.8 KEY64640.1 - 0.58 9.8 3.7 19 5.0 0.0 3.3 2 1 1 3 3 3 0 BCL2-associated athanogene 6 RSN1_7TM PF02714.15 KEY64641.1 - 6.9e-77 258.4 14.2 1.4e-76 257.4 14.2 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY64641.1 - 3e-43 147.3 0.3 8.5e-43 145.8 0.3 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEY64641.1 - 1.4e-24 87.3 0.1 2.3e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEY64641.1 - 2.1e-22 79.1 0.1 1.1e-21 76.8 0.0 2.3 3 0 0 3 3 3 1 Extracellular tail, of 10TM putative phosphate transporter CCSMST1 PF15013.6 KEY64641.1 - 0.17 12.0 2.1 14 6.0 0.0 2.8 2 0 0 2 2 2 0 CCSMST1 family APH PF01636.23 KEY64642.1 - 3.7e-30 105.6 0.3 6.8e-30 104.7 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KEY64642.1 - 0.0031 16.8 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.11 KEY64642.1 - 0.0034 16.3 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 KEY64642.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase adh_short PF00106.25 KEY64643.1 - 1.3e-24 86.7 0.0 7.7e-24 84.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64643.1 - 1.1e-16 61.1 0.1 2.7e-16 59.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY64643.1 - 4.4e-05 23.1 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY64643.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Stig1 PF04885.13 KEY64644.1 - 7.1e-40 136.7 176.2 7.8e-08 32.9 21.8 7.2 1 1 6 7 7 7 7 Stigma-specific protein, Stig1 HET PF06985.11 KEY64645.1 - 7.6e-13 49.0 8.6 1.3e-10 41.8 2.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PAS_11 PF14598.6 KEY64645.1 - 0.087 13.0 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 PAS domain Cu_amine_oxid PF01179.20 KEY64646.1 - 2.3e-119 399.0 5.7 2.9e-119 398.6 5.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KEY64646.1 - 2.4e-23 81.7 1.3 6.3e-23 80.3 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KEY64646.1 - 0.00039 20.6 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SNF2_N PF00176.23 KEY64647.1 - 2.1e-10 39.9 0.1 1.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY64647.1 - 0.011 16.1 0.1 0.047 14.0 0.0 2.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain OPT PF03169.15 KEY64648.1 - 2e-89 300.9 43.2 2.6e-89 300.6 43.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KEY64648.1 - 0.032 14.5 0.5 0.032 14.5 0.5 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3093) DUF4191 PF13829.6 KEY64648.1 - 0.31 10.4 1.5 1.3 8.3 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF1929 PF09118.11 KEY64649.1 - 1.2e-23 83.3 0.1 2.6e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KEY64649.1 - 3.3e-13 49.4 1.3 0.0031 17.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KEY64649.1 - 6.1e-12 44.9 0.0 0.00022 20.7 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KEY64649.1 - 3.6e-08 33.3 8.2 0.00074 19.5 0.2 5.2 3 2 1 4 4 4 2 Galactose oxidase, central domain PAN_1 PF00024.26 KEY64649.1 - 2.8e-07 30.4 0.2 5.6e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 PAN domain Glyoxal_oxid_N PF07250.11 KEY64649.1 - 3.6e-06 26.4 0.0 0.039 13.1 0.0 3.0 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KEY64649.1 - 1.5e-05 24.7 0.0 1.2 9.2 0.0 5.0 4 2 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KEY64649.1 - 0.015 15.6 0.4 0.18 12.1 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain PAN_4 PF14295.6 KEY64649.1 - 0.062 13.2 1.4 0.22 11.5 1.4 1.9 1 0 0 1 1 1 0 PAN domain TP_methylase PF00590.20 KEY64649.1 - 0.064 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases adh_short PF00106.25 KEY64650.1 - 1.3e-23 83.5 0.0 1.7e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64650.1 - 2.6e-14 53.3 0.0 4.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY64650.1 - 4.5e-07 29.6 0.0 7.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY64650.1 - 6.7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEY64650.1 - 0.0035 16.8 0.1 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase MHYT PF03707.16 KEY64651.1 - 0.016 15.4 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat MFS_1 PF07690.16 KEY64652.1 - 8.3e-15 54.6 13.7 8.3e-15 54.6 13.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY64652.1 - 4.5e-09 35.7 0.4 4.5e-09 35.7 0.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Cu-oxidase_3 PF07732.15 KEY64653.1 - 2e-42 143.9 1.8 1.5e-40 137.9 0.7 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEY64653.1 - 1.3e-40 138.3 0.9 1.3e-40 138.3 0.9 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY64653.1 - 2.7e-37 128.3 0.1 1e-34 119.9 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase SNF2_N PF00176.23 KEY64654.1 - 9.8e-16 57.4 0.0 1.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 KEY64654.1 - 0.0032 17.5 0.0 0.92 9.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY64654.1 - 0.011 16.1 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DEAD PF00270.29 KEY64654.1 - 0.069 12.9 0.0 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase Arginase PF00491.21 KEY64655.1 - 3.9e-93 312.0 0.0 5.2e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KEY64655.1 - 0.00062 20.0 0.1 0.0013 19.0 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Fungal_trans PF04082.18 KEY64656.1 - 3.5e-20 72.2 0.1 5.8e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64656.1 - 1.6e-05 25.0 9.3 2.6e-05 24.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 KEY64657.1 - 3.7e-104 349.0 40.2 4.3e-104 348.8 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY64657.1 - 6.4e-36 124.1 43.9 8.7e-36 123.7 43.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5133 PF17196.4 KEY64658.1 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF5133) AAA PF00004.29 KEY64659.1 - 2.9e-16 60.1 0.0 7.8e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEY64659.1 - 0.0042 16.4 0.4 0.011 15.1 0.4 1.7 1 0 0 1 1 1 1 KaiC AAA_5 PF07728.14 KEY64659.1 - 0.0049 16.9 0.0 0.19 11.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY64659.1 - 0.0052 17.1 1.2 0.06 13.6 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY64659.1 - 0.0053 16.9 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY64659.1 - 0.0083 16.5 0.9 0.11 12.9 0.2 2.5 2 1 1 3 3 3 1 AAA ATPase domain Torsin PF06309.11 KEY64659.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.6 KEY64659.1 - 0.035 14.4 0.6 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KEY64659.1 - 0.038 14.3 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 KEY64659.1 - 0.06 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AalphaY_MDB PF04611.12 KEY64659.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region AAA_30 PF13604.6 KEY64659.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEY64659.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Clr5 PF14420.6 KEY64660.1 - 1.9e-17 63.2 0.5 4.5e-17 62.0 0.5 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KEY64660.1 - 0.028 14.7 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M28 PF04389.17 KEY64661.1 - 3.9e-36 124.6 0.0 6.9e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY64661.1 - 1.3e-06 28.2 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ADH_zinc_N_2 PF13602.6 KEY64662.1 - 2.9e-25 89.9 0.0 1.5e-24 87.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY64662.1 - 2.5e-18 66.3 0.4 2.5e-17 63.1 0.1 2.7 2 1 1 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY64662.1 - 6.2e-18 65.0 1.4 2.5e-16 59.7 0.0 3.2 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64662.1 - 1.6e-11 44.2 0.0 1.9e-10 40.7 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KEY64662.1 - 1.1e-07 31.7 0.1 6.2e-07 29.3 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 KEY64662.1 - 0.00018 20.8 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KEY64662.1 - 0.00058 19.8 0.2 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 KR domain GLTT PF01744.20 KEY64662.1 - 0.37 10.6 3.1 6.2 6.7 0.2 2.7 2 0 0 2 2 2 0 GLTT repeat (6 copies) Abhydrolase_1 PF00561.20 KEY64663.1 - 1.7e-17 64.0 0.2 8.2e-17 61.7 0.1 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY64663.1 - 1.3e-12 47.5 0.0 2.5e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY64663.1 - 4.5e-11 43.8 0.0 5.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KEY64663.1 - 1.7e-08 33.5 0.0 2.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KEY64663.1 - 0.012 15.6 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KEY64664.1 - 0.0012 19.5 0.1 0.0022 18.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEY64664.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KEY64664.1 - 0.093 12.0 0.0 0.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short PF00106.25 KEY64665.1 - 7.8e-39 133.1 1.7 1.1e-38 132.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64665.1 - 3.2e-29 102.2 0.6 4e-29 101.8 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 KEY64665.1 - 4e-06 27.1 0.1 7.6e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KEY64665.1 - 4.1e-06 26.8 0.2 6e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY64665.1 - 1.8e-05 24.2 0.0 5.7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KEY64665.1 - 2.5e-05 24.0 0.3 4.9e-05 23.0 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KEY64665.1 - 3.6e-05 23.7 0.1 5.6e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Rossmann-like PF10727.9 KEY64665.1 - 0.00055 19.8 1.6 0.0014 18.5 1.5 1.8 1 1 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.17 KEY64665.1 - 0.0025 18.3 0.1 0.0055 17.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 KEY64665.1 - 0.0037 17.1 0.3 0.0073 16.2 0.3 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 KEY64665.1 - 0.0045 16.6 0.1 0.0073 16.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KEY64665.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KEY64665.1 - 0.053 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KEY64665.1 - 0.085 11.9 0.1 0.65 9.0 0.1 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain PAE PF03283.13 KEY64665.1 - 0.13 11.4 0.3 0.17 11.0 0.3 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_M14 PF00246.24 KEY64666.1 - 6.6e-47 160.7 0.0 9e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KEY64666.1 - 0.14 12.5 0.0 0.89 10.0 0.0 2.4 3 0 0 3 3 3 0 Carboxypeptidase activation peptide ketoacyl-synt PF00109.26 KEY64667.1 - 1.2e-68 231.5 0.1 2.5e-68 230.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEY64667.1 - 5.3e-58 196.6 0.2 3.6e-57 193.9 0.1 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 KEY64667.1 - 5.2e-51 173.1 0.3 1.5e-50 171.6 0.1 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEY64667.1 - 2e-48 165.5 0.2 4e-48 164.6 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY64667.1 - 4.7e-37 126.6 0.0 3.9e-36 123.7 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY64667.1 - 2.2e-14 53.8 0.0 2.2e-14 53.8 0.0 2.3 3 0 0 3 3 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KEY64667.1 - 5.5e-13 50.1 0.0 5.6e-12 46.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY64667.1 - 3.1e-12 46.6 0.1 1.8e-11 44.1 0.1 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY64667.1 - 6.7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 KEY64667.1 - 6.1e-06 26.1 0.2 1.4e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY64667.1 - 1.5e-05 25.3 0.0 3.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEY64667.1 - 0.00054 19.4 0.1 0.002 17.5 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KEY64667.1 - 0.0077 16.1 0.2 0.028 14.3 0.2 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 KEY64668.1 - 6.9e-58 196.0 3.7 1.5e-57 194.9 3.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY64668.1 - 2.8e-38 131.3 2.0 5.4e-38 130.4 2.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY64668.1 - 5.4e-08 33.0 1.5 6.7e-08 32.6 0.3 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY64668.1 - 0.0079 15.7 0.1 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.11 KEY64669.1 - 2.8e-07 30.1 0.3 2.7e-06 27.0 0.0 2.4 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KEY64669.1 - 0.023 14.4 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) adh_short PF00106.25 KEY64670.1 - 1.1e-36 126.1 0.1 1.5e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64670.1 - 2e-27 96.3 0.0 2.6e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY64670.1 - 0.005 16.3 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY64670.1 - 0.028 14.7 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KEY64670.1 - 0.032 14.2 0.2 0.091 12.7 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase KR PF08659.10 KEY64670.1 - 0.071 13.0 0.3 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 KR domain DUF1382 PF07131.11 KEY64670.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) p450 PF00067.22 KEY64672.1 - 5.4e-50 170.5 0.0 3.5e-45 154.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KEY64673.1 - 1.6e-70 238.1 0.0 1.9e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IQ_SEC7_PH PF16453.5 KEY64673.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PH domain adh_short PF00106.25 KEY64674.1 - 4e-28 98.2 0.0 1.9e-22 79.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64674.1 - 1.3e-16 60.9 0.0 1.8e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64674.1 - 2.6e-08 34.0 0.2 4.7e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY64674.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Trp_DMAT PF11991.8 KEY64675.1 - 9e-92 308.3 0.5 1.1e-91 308.1 0.5 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.23 KEY64676.1 - 7e-22 77.7 0.6 1.1e-21 77.0 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY64676.1 - 0.002 18.2 0.6 0.0057 16.7 0.6 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KEY64677.1 - 1.1e-18 67.4 0.1 1.7e-16 60.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64677.1 - 3.3e-11 43.2 0.1 1.2e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64677.1 - 1.9e-09 37.7 0.4 2.7e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 KR domain KORA PF16509.5 KEY64677.1 - 0.03 14.6 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Fungal_trans_2 PF11951.8 KEY64678.1 - 9e-06 24.7 1.6 1.4e-05 24.1 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY64679.1 - 2.6e-25 89.0 0.0 5.2e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64679.1 - 2.8e-11 43.4 0.0 1.1e-10 41.4 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64679.1 - 6.1e-06 26.3 0.2 1.6e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY64679.1 - 4.7e-05 23.0 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KEY64679.1 - 0.021 14.7 0.1 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus FAD_binding_3 PF01494.19 KEY64680.1 - 9.2e-21 74.5 1.9 8.8e-20 71.2 1.9 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY64680.1 - 2e-06 27.7 2.7 0.0014 18.3 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY64680.1 - 7.6e-06 25.2 5.7 0.014 14.4 0.2 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KEY64680.1 - 2.8e-05 23.6 0.8 0.095 12.0 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KEY64680.1 - 6.1e-05 22.1 0.7 0.00046 19.2 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KEY64680.1 - 0.00015 21.9 0.2 0.00015 21.9 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY64680.1 - 0.00018 22.0 1.0 0.12 12.9 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY64680.1 - 0.0034 16.7 7.3 0.015 14.5 0.3 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY64680.1 - 0.023 14.0 0.2 0.18 11.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Chromate_transp PF02417.15 KEY64680.1 - 0.03 14.5 1.0 0.091 12.9 1.0 1.9 1 0 0 1 1 1 0 Chromate transporter Thi4 PF01946.17 KEY64680.1 - 0.046 13.0 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KEY64680.1 - 0.59 9.2 4.6 0.091 11.8 0.7 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KEY64680.1 - 0.94 9.5 2.9 15 5.6 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 KEY64681.1 - 1.1e-11 44.2 2.6 2e-11 43.4 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY64681.1 - 8.1e-08 32.3 15.1 1.5e-07 31.4 15.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY64682.1 - 1.6e-25 89.8 0.1 2.1e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64682.1 - 2.2e-16 60.1 0.0 2.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF637 PF04830.13 KEY64682.1 - 0.0088 15.9 0.2 2 8.2 0.0 2.2 2 0 0 2 2 2 2 Possible hemagglutinin (DUF637) Epimerase PF01370.21 KEY64682.1 - 0.03 13.8 0.2 0.42 10.0 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY64682.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 KEY64682.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding FAD_binding_4 PF01565.23 KEY64683.1 - 4.2e-26 91.3 2.7 4.7e-26 91.2 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY64683.1 - 8.2e-05 22.6 0.2 0.00021 21.3 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KEY64684.1 - 9.3e-34 116.6 0.0 1.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY64684.1 - 3e-28 99.0 0.0 4.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY64684.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY64684.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KEY64684.1 - 7e-06 26.0 0.1 1.3e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY64684.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_2 PF13477.6 KEY64684.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF1611_N PF17396.2 KEY64684.1 - 0.073 13.3 0.0 5.5 7.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DSBA PF01323.20 KEY64686.1 - 8.4e-32 110.5 0.0 1e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Sugar_tr PF00083.24 KEY64688.1 - 2.6e-80 270.5 20.5 3e-80 270.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY64688.1 - 1.9e-13 50.1 45.7 3e-08 33.0 16.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KEY64689.1 - 9.8e-21 74.0 3.7 1.8e-20 73.1 3.7 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KEY64690.1 - 4.1e-45 154.2 57.2 3.2e-42 144.7 42.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY64690.1 - 4.6e-07 29.0 11.6 4.6e-07 29.0 11.6 2.3 2 0 0 2 2 2 2 MFS_1 like family DEFB136 PF17333.2 KEY64690.1 - 1 9.4 2.7 20 5.2 0.2 2.6 2 0 0 2 2 2 0 Beta defensin 136 Abhydrolase_1 PF00561.20 KEY64691.1 - 6.6e-13 48.9 0.5 2.2e-11 43.9 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY64691.1 - 8.5e-08 33.1 1.7 1.8e-07 32.0 1.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY64691.1 - 0.0012 18.2 0.2 0.0049 16.2 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KEY64691.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 KEY64691.1 - 0.059 13.2 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.22 KEY64692.1 - 5.8e-26 91.2 0.0 1.6e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SGL PF08450.12 KEY64693.1 - 5.9e-13 49.0 0.1 2.1e-10 40.6 0.1 2.5 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF1929 PF09118.11 KEY64694.1 - 1.7e-24 85.9 0.2 5.1e-24 84.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KEY64694.1 - 2e-19 70.0 3.5 2e-19 69.9 0.8 2.4 2 0 0 2 2 2 1 F5/8 type C domain Kelch_6 PF13964.6 KEY64694.1 - 1.9e-13 50.1 9.8 6.2e-07 29.5 0.0 5.0 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KEY64694.1 - 1.9e-09 36.9 9.3 0.0031 17.1 0.6 5.0 3 2 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KEY64694.1 - 5e-09 36.0 11.5 1.1e-05 25.3 0.0 5.3 4 1 0 4 4 4 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KEY64694.1 - 1.7e-08 34.0 0.3 0.00012 21.3 0.4 2.8 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KEY64694.1 - 1.5e-07 31.1 0.2 0.021 14.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DUF5000 PF16391.5 KEY64694.1 - 0.0036 17.4 0.3 0.4 10.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function Kelch_3 PF13415.6 KEY64694.1 - 0.054 13.8 15.4 0.07 13.5 0.1 5.6 6 1 0 6 6 6 0 Galactose oxidase, central domain Amino_oxidase PF01593.24 KEY64695.1 - 6.6e-46 157.5 0.0 8.6e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY64695.1 - 1.2e-12 47.8 0.0 2.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY64695.1 - 1.3e-05 24.6 0.1 0.00012 21.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY64695.1 - 0.00011 21.9 4.0 0.00038 20.2 2.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY64695.1 - 0.00013 22.5 0.7 0.00052 20.5 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY64695.1 - 0.00037 20.5 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY64695.1 - 0.00065 18.5 0.3 0.0024 16.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KEY64695.1 - 0.00072 18.9 0.2 0.0027 17.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KEY64695.1 - 0.0065 15.8 0.9 0.013 14.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEY64695.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KEY64695.1 - 0.012 14.7 0.5 0.019 14.1 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KEY64695.1 - 0.019 14.9 0.4 0.089 12.7 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KEY64695.1 - 0.051 12.0 0.3 0.072 11.5 0.3 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Ank_4 PF13637.6 KEY64696.1 - 8.9e-12 45.3 0.3 2.6e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY64696.1 - 7.1e-10 39.3 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY64696.1 - 1.4e-09 38.0 3.0 8.5e-07 29.1 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY64696.1 - 9.8e-07 29.0 0.4 0.0013 19.1 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KEY64696.1 - 2.9e-06 27.2 0.2 0.15 12.7 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat SesA PF17107.5 KEY64696.1 - 5.4e-05 23.4 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KEY64696.1 - 0.00056 19.3 0.4 0.001 18.5 0.4 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins APH PF01636.23 KEY64697.1 - 1.5e-12 48.0 0.1 5.7e-12 46.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY64697.1 - 6.7e-05 22.6 0.1 0.00014 21.5 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KEY64697.1 - 0.3 9.9 0.0 0.47 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Amidase PF01425.21 KEY64699.1 - 2.4e-34 119.1 2.7 5.2e-34 118.0 2.6 1.5 2 0 0 2 2 2 1 Amidase PHO4 PF01384.20 KEY64700.1 - 5.9e-99 331.3 19.6 6.9e-99 331.1 19.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Pro-NT_NN PF07421.11 KEY64700.1 - 0.022 15.0 0.3 9.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Neurotensin/neuromedin N precursor UPF0444 PF15475.6 KEY64700.1 - 1.8 8.9 9.2 12 6.2 0.3 2.6 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DUF1524 PF07510.11 KEY64701.1 - 0.00042 20.2 0.0 0.00052 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Glyco_transf_34 PF05637.12 KEY64702.1 - 4.5e-16 59.3 0.2 1.1e-15 58.1 0.2 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family BUD22 PF09073.10 KEY64702.1 - 0.11 11.8 37.4 0.18 11.1 37.4 1.5 1 0 0 1 1 1 0 BUD22 Lipase_GDSL_2 PF13472.6 KEY64703.1 - 2.6e-07 31.2 0.3 3.2e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY64703.1 - 2.8e-05 24.2 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.21 KEY64704.1 - 3.2e-70 237.3 0.0 2.8e-69 234.2 0.0 1.9 1 1 1 2 2 2 2 Amidase zf-C2H2 PF00096.26 KEY64705.1 - 0.00058 20.2 0.1 0.00058 20.2 0.1 4.3 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-TRAF PF02176.18 KEY64705.1 - 0.029 15.1 1.5 0.029 15.1 1.5 3.0 2 1 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 KEY64705.1 - 0.043 14.2 0.3 0.043 14.2 0.3 4.1 3 1 1 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY64705.1 - 0.49 11.4 0.0 0.49 11.4 0.0 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger DUF2310 PF10071.9 KEY64705.1 - 0.69 9.1 4.4 0.2 10.9 0.9 1.8 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DZR PF12773.7 KEY64705.1 - 1.4 9.0 5.2 0.51 10.4 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon SlyX PF04102.12 KEY64708.1 - 0.0035 17.9 0.3 0.01 16.4 0.3 1.7 1 0 0 1 1 1 1 SlyX TolA_bind_tri PF16331.5 KEY64708.1 - 0.029 14.5 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3138 PF11336.8 KEY64708.1 - 2.3 6.7 4.5 3.2 6.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) WSC PF01822.19 KEY64710.1 - 9.1e-26 89.9 12.3 8.9e-16 57.9 12.1 3.0 2 1 0 2 2 2 2 WSC domain Glyco_hydro_11 PF00457.17 KEY64712.1 - 2.1e-42 144.7 7.9 3.3e-42 144.1 7.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_tranf_2_3 PF13641.6 KEY64714.1 - 1.4e-24 87.3 0.0 1.9e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEY64714.1 - 2.5e-06 27.1 0.0 6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEY64714.1 - 4.4e-06 26.6 0.0 1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Med19 PF10278.9 KEY64715.1 - 0.014 15.3 0.9 0.027 14.4 0.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Clr5 PF14420.6 KEY64716.1 - 4.1e-19 68.6 8.1 2.3e-18 66.2 2.2 3.0 3 0 0 3 3 3 2 Clr5 domain FAD-oxidase_C PF02913.19 KEY64717.1 - 2.6e-62 210.7 0.1 4.3e-62 210.0 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEY64717.1 - 7e-36 123.0 0.0 1.3e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0183 PF03676.14 KEY64718.1 - 2.5e-57 195.0 0.0 4.9e-33 115.0 0.0 3.5 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 KEY64719.1 - 1.1e-110 369.7 2.8 1.1e-110 369.7 2.8 1.8 2 0 0 2 2 2 1 Kinesin motor domain MFS_1 PF07690.16 KEY64719.1 - 1e-44 153.0 57.0 1e-44 153.0 57.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY64719.1 - 1.3e-26 93.2 11.9 2.2e-26 92.5 11.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Microtub_bd PF16796.5 KEY64719.1 - 8.6e-26 90.7 1.6 2.6e-25 89.1 0.1 2.6 2 0 0 2 2 2 1 Microtubule binding Sugar_tr PF00083.24 KEY64719.1 - 3.3e-13 49.3 12.3 3.3e-13 49.3 12.3 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Microtub_bind PF13931.6 KEY64719.1 - 7.8e-07 29.5 0.1 7.8e-07 29.5 0.1 5.2 5 1 1 6 6 6 1 Kinesin-associated microtubule-binding ACP_PD PF04336.12 KEY64719.1 - 5.4 7.5 6.8 8.2 6.9 0.2 4.0 3 2 1 4 4 4 0 Acyl carrier protein phosphodiesterase SseC PF04888.12 KEY64719.1 - 5.6 6.5 26.7 1.1e+02 2.3 17.3 3.8 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family RRN9 PF10680.9 KEY64720.1 - 4.3e-15 55.7 2.8 2.4e-14 53.4 2.8 2.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 KEY64720.1 - 0.22 12.0 0.0 0.51 10.9 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pescadillo_N PF06732.11 KEY64721.1 - 3.1e-123 410.7 0.1 3.1e-123 410.7 0.1 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KEY64721.1 - 0.007 16.8 0.0 0.033 14.6 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain EBV-NA3 PF05009.12 KEY64721.1 - 2.3 7.7 5.3 5.5 6.4 5.3 1.7 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PIG-U PF06728.13 KEY64722.1 - 1.2e-123 413.0 22.4 1.4e-123 412.8 22.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Tom37 PF10568.9 KEY64723.1 - 2.7e-33 114.9 0.1 4.7e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KEY64723.1 - 1.4e-07 32.2 0.0 7.4e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEY64723.1 - 4.6e-06 26.3 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY64723.1 - 0.018 15.1 0.0 0.058 13.4 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hep_59 PF07052.11 KEY64724.1 - 0.0049 17.6 4.5 0.0059 17.3 4.5 1.2 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Ntox15 PF15604.6 KEY64724.1 - 0.0071 16.5 2.1 0.0079 16.3 1.0 1.5 1 1 1 2 2 2 2 Novel toxin 15 Metal_resist PF13801.6 KEY64724.1 - 0.1 12.8 6.0 0.15 12.2 6.0 1.5 1 1 0 1 1 1 0 Heavy-metal resistance Jnk-SapK_ap_N PF09744.9 KEY64724.1 - 0.33 11.2 14.1 0.38 11.0 14.1 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KEY64724.1 - 0.47 8.9 3.3 0.48 8.9 3.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sugarporin_N PF11471.8 KEY64725.1 - 0.11 12.4 1.9 0.2 11.6 1.9 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-C2H2 PF00096.26 KEY64726.1 - 6.9e-06 26.2 11.9 0.0029 18.0 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY64726.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY64726.1 - 0.00038 21.1 11.3 0.072 14.0 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KEY64726.1 - 1.3 8.8 5.6 2.4 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2434 PF10361.9 KEY64728.1 - 1.2e-120 401.9 11.1 1.5e-120 401.6 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 KEY64729.1 - 2.2e-37 128.1 0.8 1.2e-36 125.8 0.3 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 ACC_central PF08326.12 KEY64729.1 - 0.039 12.2 0.1 2.4 6.3 0.1 2.1 2 0 0 2 2 2 0 Acetyl-CoA carboxylase, central region SRX PF09201.10 KEY64729.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit DHFR_2 PF06442.11 KEY64729.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase Gelsolin PF00626.22 KEY64730.1 - 2e-35 120.5 0.0 1.6e-13 50.3 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Exo_endo_phos PF03372.23 KEY64731.1 - 0.00016 21.3 3.2 0.00048 19.7 3.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KEY64731.1 - 0.085 12.7 0.0 0.59 10.0 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase GFA PF04828.14 KEY64732.1 - 7.3e-15 55.1 0.1 2.2e-14 53.6 0.1 1.8 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme EI24 PF07264.11 KEY64733.1 - 7.8e-09 36.0 20.9 1.4e-08 35.2 20.9 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DDE_Tnp_1_7 PF13843.6 KEY64734.1 - 5.3e-37 127.9 0.0 6.3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 SAP PF02037.27 KEY64734.1 - 0.2 11.4 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 SAP domain Abhydrolase_4 PF08386.10 KEY64736.1 - 1.4e-20 73.3 0.0 2.8e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY64736.1 - 3.1e-14 53.2 0.0 3.5e-06 26.8 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF3638 PF12340.8 KEY64737.1 - 1.6e-92 309.0 0.5 2.7e-92 308.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEY64737.1 - 2.3e-15 55.7 0.1 2.3e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Sel1 PF08238.12 KEY64738.1 - 8e-16 58.1 22.4 7.5e-06 26.5 0.1 7.5 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KEY64738.1 - 0.0075 16.0 0.2 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TraI_2B PF18340.1 KEY64738.1 - 0.063 13.4 3.5 0.11 12.6 1.0 2.3 2 1 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain TPR_8 PF13181.6 KEY64738.1 - 1.4 9.3 5.7 2.2 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KEY64739.1 - 2.7e-19 69.6 0.0 4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KEY64739.1 - 0.0036 16.7 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Coatomer_WDAD PF04053.14 KEY64740.1 - 2.2e-147 491.7 0.0 4e-147 490.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KEY64740.1 - 1.2e-99 333.9 0.0 1.6e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KEY64740.1 - 3.9e-37 125.6 16.8 2.7e-07 31.1 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64740.1 - 4.1e-09 36.6 0.9 0.00014 22.1 0.0 5.5 3 2 5 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain IPPT PF01715.17 KEY64740.1 - 0.032 14.0 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 IPP transferase Nup160 PF11715.8 KEY64740.1 - 0.083 11.5 6.7 5.9 5.4 0.0 3.8 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Glyco_transf_24 PF18404.1 KEY64741.1 - 1.8e-148 493.1 0.9 2.7e-148 492.6 0.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KEY64741.1 - 1.5e-64 218.4 0.0 3.3e-64 217.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KEY64741.1 - 5.4e-59 199.7 0.1 1.3e-56 191.9 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KEY64741.1 - 1.3e-45 155.7 0.0 3.6e-45 154.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KEY64741.1 - 3.9e-41 140.1 0.0 4.4e-40 136.7 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KEY64741.1 - 4.3e-41 139.4 0.0 7.9e-41 138.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KEY64741.1 - 6.3e-05 22.7 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PAS_9 PF13426.7 KEY64742.1 - 4.1e-27 94.5 5.2 3.4e-18 65.8 0.1 4.4 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 KEY64742.1 - 9.1e-23 80.4 0.0 1.7e-12 47.4 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KEY64742.1 - 1.1e-18 67.3 14.0 1.6e-07 31.3 0.0 5.9 6 1 0 6 6 6 3 PAS fold GATA PF00320.27 KEY64742.1 - 7.1e-15 54.3 8.1 1.5e-14 53.3 8.1 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KEY64742.1 - 1.4e-11 44.6 0.0 2.8e-05 24.3 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 KEY64742.1 - 9.4e-06 26.3 2.7 0.14 12.8 0.0 4.6 4 0 0 4 4 4 1 PAS fold Herpes_UL6 PF01763.16 KEY64742.1 - 0.31 9.5 18.4 0.55 8.7 18.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like LMBR1 PF04791.16 KEY64742.1 - 3.1 6.6 9.1 6.1 5.6 9.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF445 PF04286.12 KEY64742.1 - 3.9 7.2 15.1 7.8 6.2 14.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) GerPC PF10737.9 KEY64742.1 - 8.5 6.4 27.2 0.31 11.1 20.3 2.0 2 0 0 2 2 2 0 Spore germination protein GerPC Importin_rep_4 PF18808.1 KEY64744.1 - 6.5e-31 106.5 13.8 7.4e-31 106.3 1.8 5.0 5 1 1 6 6 5 1 Importin repeat HEAT_EZ PF13513.6 KEY64744.1 - 2.5e-24 85.3 12.1 6.7e-11 42.5 0.3 9.6 8 1 2 10 10 10 4 HEAT-like repeat Importin_rep_5 PF18816.1 KEY64744.1 - 7e-21 74.3 3.6 1.3e-20 73.5 0.6 3.0 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 KEY64744.1 - 5.8e-19 66.6 20.3 0.0016 18.5 0.0 12.1 13 0 0 13 13 10 3 HEAT repeat HEAT_2 PF13646.6 KEY64744.1 - 1.2e-18 67.3 13.1 1.8e-06 28.3 0.0 8.1 3 2 3 6 6 6 4 HEAT repeats Importin_rep_6 PF18829.1 KEY64744.1 - 3.2e-13 49.8 4.2 8.3e-13 48.4 0.2 3.2 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KEY64744.1 - 9.2e-12 45.4 2.7 0.021 15.4 0.0 8.0 6 1 3 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEY64744.1 - 5e-09 36.4 0.6 1.4 8.9 0.0 5.7 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KEY64744.1 - 1.5e-08 34.2 4.1 4.4e-07 29.4 0.1 4.1 4 1 0 5 5 5 1 RNAPII transcription regulator C-terminal RIX1 PF08167.12 KEY64744.1 - 2.1e-08 34.2 0.1 0.00021 21.1 0.0 4.8 4 1 1 5 5 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KEY64744.1 - 1.9e-07 30.9 0.8 0.0055 16.3 0.2 5.3 5 1 1 6 6 6 1 CLASP N terminal DRIM PF07539.12 KEY64744.1 - 1e-06 27.4 3.0 0.00059 18.3 0.3 4.3 3 3 1 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 KEY64744.1 - 9.2e-05 22.4 0.4 2.7 7.9 0.0 5.7 4 1 0 6 6 6 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KEY64744.1 - 0.00017 20.3 2.2 0.015 13.9 0.5 3.7 3 1 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.19 KEY64744.1 - 0.00038 20.3 1.6 0.0039 17.1 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KEY64744.1 - 0.00094 19.1 4.1 1.7 8.8 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3535 PF12054.8 KEY64744.1 - 0.0017 17.7 1.6 0.0079 15.5 0.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) Telomere_reg-2 PF10193.9 KEY64744.1 - 0.0024 18.3 5.7 0.075 13.5 1.8 3.9 4 1 0 4 4 3 1 Telomere length regulation protein V-ATPase_H_N PF03224.14 KEY64744.1 - 0.0058 16.0 5.7 0.088 12.1 0.3 3.2 2 1 1 3 3 3 1 V-ATPase subunit H DUF4042 PF13251.6 KEY64744.1 - 0.0069 16.1 0.7 19 4.9 0.0 5.4 5 1 2 7 7 7 0 Domain of unknown function (DUF4042) CAS_CSE1 PF03378.15 KEY64744.1 - 0.01 14.3 0.4 1.9 6.9 0.1 3.5 2 1 2 4 4 4 0 CAS/CSE protein, C-terminus MIF4G_like_2 PF09090.11 KEY64744.1 - 0.017 14.6 0.2 0.076 12.5 0.0 2.1 2 0 0 2 2 2 0 MIF4G like Cohesin_HEAT PF12765.7 KEY64744.1 - 0.04 14.2 0.4 12 6.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 KEY64744.1 - 0.067 12.4 0.1 5.4 6.1 0.0 3.4 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 KEY64744.1 - 0.23 11.4 1.7 12 5.9 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 KEY64744.1 - 0.38 11.0 5.3 1.6 9.0 0.5 4.2 5 1 1 6 6 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Apolipoprotein PF01442.18 KEY64744.1 - 1.6 8.5 10.6 1.4 8.7 0.1 3.6 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain CBS PF00571.28 KEY64746.1 - 7.8e-18 64.7 4.5 5e-07 30.1 0.1 5.5 5 1 0 5 5 5 4 CBS domain Y_phosphatase PF00102.27 KEY64747.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Mem_trans PF03547.18 KEY64747.1 - 0.24 9.7 0.3 0.28 9.5 0.3 1.0 1 0 0 1 1 1 0 Membrane transport protein Glyco_hydro_17 PF00332.18 KEY64750.1 - 1.4e-05 24.9 0.1 6.4e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 KEY64751.1 - 3.6e-38 131.7 0.0 4.7e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY64751.1 - 0.0022 16.6 0.0 0.0037 15.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Mog1 PF04603.12 KEY64752.1 - 8.9e-41 139.5 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 KEY64753.1 - 1.4e-37 128.0 3.3 3e-37 126.9 3.3 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KEY64753.1 - 2.4e-09 37.0 7.0 4.6e-09 36.0 7.0 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KEY64753.1 - 0.0047 17.0 1.2 0.011 15.9 1.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain HMG_box PF00505.19 KEY64753.1 - 0.0059 17.0 0.4 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Peptidase_M90 PF06167.12 KEY64753.1 - 0.017 14.7 0.5 0.03 13.9 0.5 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 HMG_box_2 PF09011.10 KEY64753.1 - 0.038 14.6 0.2 0.092 13.3 0.2 1.7 1 0 0 1 1 1 0 HMG-box domain YABBY PF04690.13 KEY64753.1 - 0.06 13.9 0.3 0.06 13.9 0.3 2.1 2 1 0 2 2 2 0 YABBY protein zinc_ribbon_5 PF13719.6 KEY64753.1 - 0.2 11.4 3.4 0.59 9.9 3.4 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF4379 PF14311.6 KEY64753.1 - 1.1 9.7 5.5 5.3 7.5 5.5 2.2 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Glucan_synthase PF02364.15 KEY64754.1 - 0 1376.7 0.0 0 1376.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KEY64754.1 - 6.4e-44 149.4 0.9 2.7e-43 147.4 0.9 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Gaa1 PF04114.14 KEY64755.1 - 5.9e-171 569.9 1.7 7.1e-171 569.6 1.7 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF334 PF03904.13 KEY64755.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Aconitase PF00330.20 KEY64756.1 - 1.3e-143 479.4 0.0 1.6e-143 479.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEY64756.1 - 2.4e-43 147.6 0.0 4.1e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sdh5 PF03937.16 KEY64756.1 - 0.2 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase zf-C2H2_jaz PF12171.8 KEY64757.1 - 1.1e-08 35.1 0.2 3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 KEY64757.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 DASH_Dam1 PF08653.10 KEY64758.1 - 4.3e-27 93.7 2.2 6e-27 93.2 2.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 KEY64759.1 - 4.7e-45 153.2 0.0 8.4e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY64759.1 - 6.5e-13 48.7 0.1 1.4e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KEY64759.1 - 3e-07 30.7 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4805 PF16063.5 KEY64759.1 - 0.081 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Metal_resist PF13801.6 KEY64759.1 - 0.088 13.0 0.0 0.088 13.0 0.0 2.8 3 0 0 3 3 3 0 Heavy-metal resistance HIT PF01230.23 KEY64760.1 - 3.1e-21 75.9 0.1 3.8e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEY64760.1 - 1.2e-13 51.5 0.0 1.6e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KEY64760.1 - 1.9e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ICAT PF06384.11 KEY64760.1 - 0.0052 17.0 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT CSTF2_hinge PF14327.6 KEY64760.1 - 0.038 14.4 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Rhomboid PF01694.22 KEY64761.1 - 7.9e-14 51.9 8.4 7.9e-14 51.9 8.4 1.6 2 0 0 2 2 2 1 Rhomboid family DUF3487 PF11990.8 KEY64761.1 - 0.092 12.6 0.1 0.092 12.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) DUF2070 PF09843.9 KEY64761.1 - 3.9 5.7 13.1 5 5.3 13.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PCI PF01399.27 KEY64762.1 - 2.4e-10 40.8 0.0 5.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KEY64762.1 - 3.8e-07 29.6 1.2 7.8e-07 28.6 1.2 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KEY64762.1 - 0.041 13.4 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) NmrA PF05368.13 KEY64763.1 - 6e-16 58.7 0.0 1.1e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEY64763.1 - 2.3e-13 50.2 0.1 4.1e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY64763.1 - 4.1e-13 49.6 0.0 7.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY64763.1 - 2.6e-10 39.8 0.1 1.5e-09 37.3 0.1 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY64763.1 - 2e-06 27.5 0.1 3.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEY64763.1 - 0.00016 20.9 0.0 0.0098 15.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KEY64763.1 - 0.00019 21.0 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KEY64763.1 - 0.0026 17.0 0.2 0.48 9.5 0.0 2.5 1 1 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 KEY64763.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_synthase PF02540.17 KEY64763.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD synthase ApbA PF02558.16 KEY64763.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA N6-adenineMlase PF10237.9 KEY64764.1 - 1.6e-53 180.8 0.0 2e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.29 KEY64765.1 - 8.4e-49 166.4 2.5 1.1e-48 165.9 2.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY64765.1 - 2.5e-30 106.2 7.2 3.9e-30 105.6 7.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KEY64765.1 - 0.00031 21.0 0.2 0.00031 21.0 0.2 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.12 KEY64765.1 - 0.006 16.1 3.2 0.79 9.3 0.0 4.1 3 1 1 4 4 4 1 TFIIB zinc-binding zf-CCHC PF00098.23 KEY64765.1 - 2.8 8.2 10.5 12 6.2 0.1 4.2 4 0 0 4 4 4 0 Zinc knuckle OrfB_Zn_ribbon PF07282.11 KEY64765.1 - 5.3 7.1 9.9 2.6 8.0 1.2 3.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Lactamase_B PF00753.27 KEY64766.1 - 1e-18 68.0 9.3 2.8e-17 63.4 8.0 2.5 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KEY64766.1 - 2e-18 66.1 0.0 4.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KEY64766.1 - 3.4e-08 33.3 0.3 5.7e-08 32.5 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEY64766.1 - 9.4e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KEY64766.1 - 0.0025 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain EthD PF07110.11 KEY64766.1 - 0.2 12.8 0.7 9.8 7.4 0.0 2.4 2 1 0 2 2 2 0 EthD domain Ytp1 PF10355.9 KEY64767.1 - 2e-116 388.1 7.4 2.9e-116 387.6 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KEY64767.1 - 4.7e-32 109.9 18.3 2.4e-29 101.2 6.9 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF2427) DUF5504 PF17608.2 KEY64767.1 - 0.58 10.3 4.5 3.5 7.8 3.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5504) PAP2_C PF14360.6 KEY64767.1 - 4 8.0 7.9 1.4 9.5 1.5 3.2 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Rsa3 PF14615.6 KEY64768.1 - 1.9e-18 65.7 0.1 2.4e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UAF_Rrn10 PF05234.11 KEY64768.1 - 0.029 14.6 0.0 0.032 14.5 0.0 1.0 1 0 0 1 1 1 0 UAF complex subunit Rrn10 SNF2_N PF00176.23 KEY64769.1 - 1.6e-58 198.1 0.0 2.7e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KEY64769.1 - 4.9e-58 196.3 2.0 1.9e-57 194.3 1.9 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KEY64769.1 - 7.8e-16 58.4 0.0 3.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY64769.1 - 8.3e-10 38.9 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEY64769.1 - 8.2e-05 22.4 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KEY64769.1 - 0.0007 18.8 0.0 0.0045 16.2 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KEY64769.1 - 0.0034 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Mito_carr PF00153.27 KEY64770.1 - 6.1e-48 160.7 2.4 1.4e-20 73.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Wzy_C PF04932.15 KEY64770.1 - 0.028 14.1 0.3 0.094 12.3 0.2 1.8 1 1 1 2 2 2 0 O-Antigen ligase Glyco_transf_25 PF01755.17 KEY64771.1 - 0.02 14.7 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Bromodomain PF00439.25 KEY64772.1 - 3.2e-42 142.5 0.1 7.3e-21 74.0 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KEY64772.1 - 1.7e-18 66.6 0.4 3.6e-18 65.6 0.4 1.6 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KEY64772.1 - 0.00018 20.0 6.3 0.00018 20.0 6.3 1.7 2 0 0 2 2 2 1 CDC45-like protein YL1 PF05764.13 KEY64772.1 - 0.0038 17.4 10.5 0.0038 17.4 10.5 2.5 3 0 0 3 3 3 1 YL1 nuclear protein OTU PF02338.19 KEY64773.1 - 1.7e-08 35.0 0.0 3.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FmdA_AmdA PF03069.15 KEY64774.1 - 2.1e-177 589.6 0.0 2.4e-177 589.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF2161 PF09929.9 KEY64774.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) EI24 PF07264.11 KEY64775.1 - 1e-15 58.4 4.4 3.6e-13 50.1 4.4 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ni_hydr_CYTB PF01292.20 KEY64775.1 - 0.48 10.0 4.1 0.13 11.9 1.1 1.6 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Inp1 PF12634.7 KEY64776.1 - 3e-43 147.1 0.0 6.7e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 RTA1 PF04479.13 KEY64777.1 - 2.1e-42 145.1 2.2 2.9e-42 144.6 2.2 1.2 1 0 0 1 1 1 1 RTA1 like protein MtN3_slv PF03083.16 KEY64777.1 - 0.0057 16.7 1.7 0.016 15.2 1.7 1.7 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange IF2_N PF04760.15 KEY64777.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Cytochrom_B_C PF00032.17 KEY64777.1 - 4.1 7.8 7.3 4.6 7.6 0.3 3.0 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD CPSase_L_D2 PF02786.17 KEY64781.1 - 2.7e-112 373.4 0.0 3.2e-84 281.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KEY64781.1 - 9.4e-41 139.0 0.5 2.6e-40 137.5 0.5 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KEY64781.1 - 3.7e-22 78.7 0.1 1.3e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEY64781.1 - 1.5e-19 70.4 2.4 1.6e-09 37.6 0.1 2.9 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KEY64781.1 - 2.3e-11 43.5 0.0 0.00021 21.0 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KEY64781.1 - 1.1e-06 28.3 0.5 0.011 15.2 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 KEY64781.1 - 9.4e-06 25.5 0.3 0.04 13.7 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KEY64781.1 - 4.1e-05 23.7 0.2 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KEY64781.1 - 0.00033 20.3 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KEY64781.1 - 0.0034 17.0 0.1 0.039 13.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 KEY64781.1 - 0.019 15.1 0.0 0.066 13.4 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain Pkinase PF00069.25 KEY64783.1 - 5.5e-46 157.1 0.0 8.1e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64783.1 - 2.3e-20 73.0 0.0 3.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY64783.1 - 7.9e-05 22.7 0.0 0.48 10.3 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KEY64783.1 - 0.083 12.5 0.2 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Per1 PF04080.13 KEY64784.1 - 1.5e-106 355.8 12.4 1.9e-106 355.5 12.4 1.1 1 0 0 1 1 1 1 Per1-like family HLH PF00010.26 KEY64785.1 - 1.5e-12 47.2 0.2 2.8e-12 46.4 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.9 KEY64785.1 - 0.23 10.2 9.0 0.29 9.9 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Aldedh PF00171.22 KEY64786.1 - 1.6e-108 363.2 0.1 2e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.10 KEY64787.1 - 0.0015 17.6 0.4 0.044 12.8 0.1 2.8 3 0 0 3 3 3 2 PhoD-like phosphatase DUF1765 PF08578.10 KEY64788.1 - 6.4e-43 146.2 7.9 1.3e-42 145.2 7.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Zn_clus PF00172.18 KEY64789.1 - 9e-05 22.5 5.9 0.00041 20.4 5.9 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 KEY64790.1 - 9.7e-48 162.5 0.2 1.1e-47 162.2 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEY64790.1 - 0.0017 17.9 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KEY64790.1 - 0.0082 16.0 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KEY64790.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KEY64790.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Kelch_5 PF13854.6 KEY64791.1 - 3.6e-17 61.9 6.4 4.1e-06 26.6 0.1 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KEY64791.1 - 2.2e-11 43.6 5.9 0.051 13.6 0.2 6.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY64791.1 - 3.2e-11 43.1 5.7 0.066 13.5 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KEY64791.1 - 1.7e-09 37.1 3.9 0.0016 17.9 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KEY64791.1 - 9.8e-08 31.7 2.6 0.0043 17.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KEY64791.1 - 1.7e-05 25.0 18.8 1.1 9.6 0.0 6.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Transformer PF06495.11 KEY64791.1 - 0.0048 17.0 1.3 0.0095 16.0 1.3 1.5 1 0 0 1 1 1 1 Fruit fly transformer protein Nop53 PF07767.11 KEY64792.1 - 0.14 11.5 21.3 0.1 12.0 16.9 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pes-10 PF07149.11 KEY64792.1 - 1.4 7.9 4.6 2.3 7.2 4.6 1.3 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 KEY64792.1 - 1.8 6.8 11.6 3.4 5.8 11.6 1.4 1 0 0 1 1 1 0 CDC45-like protein LYRIC PF15686.5 KEY64792.1 - 3.5 7.1 15.2 7.1 6.1 8.9 2.2 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family GCV_T PF01571.21 KEY64794.1 - 2.9e-74 249.7 0.0 3.6e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KEY64794.1 - 2.3e-19 69.1 0.5 5.2e-19 67.9 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain V-ATPase_H_N PF03224.14 KEY64795.1 - 1.5e-75 254.4 0.0 1.1e-74 251.5 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KEY64795.1 - 3.2e-36 124.0 0.0 1.3e-35 122.0 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 KEY64795.1 - 0.028 14.8 0.4 0.24 11.8 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 KEY64795.1 - 0.036 14.6 1.9 8.7 7.0 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 KEY64795.1 - 0.051 13.8 0.1 3.9 8.0 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 KEY64795.1 - 0.083 13.0 0.1 27 5.0 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Trp_oprn_chp PF09534.10 KEY64796.1 - 0.0043 16.9 2.2 0.79 9.5 0.0 3.1 2 1 0 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4690 PF15756.5 KEY64796.1 - 0.0045 17.6 0.4 0.015 15.9 0.4 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Transposase_20 PF02371.16 KEY64796.1 - 0.006 16.9 4.0 0.017 15.4 4.0 1.8 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family SARAF PF06682.12 KEY64796.1 - 0.0095 15.6 3.0 0.0095 15.6 3.0 2.1 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Ribosomal_L6 PF00347.23 KEY64797.1 - 1.7e-24 86.3 7.5 7.5e-12 45.8 2.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.15 KEY64798.1 - 2.3e-129 430.3 0.5 2.6e-129 430.1 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KEY64798.1 - 0.00044 20.3 0.7 0.3 11.1 0.7 3.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KEY64798.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Nup160 PF11715.8 KEY64799.1 - 7e-133 444.1 0.0 9e-133 443.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 KEY64800.1 - 2.5e-127 423.4 0.0 3e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KEY64800.1 - 5e-09 36.0 0.0 7.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KEY64800.1 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KEY64800.1 - 6.7e-06 25.6 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KEY64800.1 - 2.1e-05 25.1 1.9 4.1e-05 24.1 0.5 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KEY64800.1 - 0.012 15.0 0.1 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KEY64800.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KEY64800.1 - 0.11 12.6 0.1 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KEY64800.1 - 0.21 10.7 0.4 0.95 8.5 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein HSP20 PF00011.21 KEY64801.1 - 5.6e-18 65.0 0.6 3.7e-12 46.3 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEY64801.1 - 6.6e-05 22.4 0.0 0.04 13.5 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA SOG2 PF10428.9 KEY64801.1 - 0.018 14.2 0.3 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein YTH PF04146.15 KEY64802.1 - 8.3e-63 211.3 0.0 1.5e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain Proteasome PF00227.26 KEY64803.1 - 8.9e-29 100.3 0.4 3.4e-28 98.4 0.2 1.9 2 1 0 2 2 2 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KEY64804.1 - 1.6e-36 126.4 0.1 3e-34 119.0 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KEY64804.1 - 3.6e-23 81.9 0.0 1.1e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 KEY64805.1 - 3.9e-23 82.2 11.0 5.2e-23 81.8 11.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEY64805.1 - 1.6e-07 31.4 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 KEY64805.1 - 0.18 11.7 2.1 0.31 10.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) HET PF06985.11 KEY64806.1 - 4.1e-22 79.1 0.2 3.7e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY64807.1 - 0.021 15.2 1.1 0.051 13.9 1.1 1.7 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DnaJ PF00226.31 KEY64808.1 - 3.3e-17 62.4 0.0 8e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CENP-F_leu_zip PF10473.9 KEY64809.1 - 0.011 15.8 7.9 0.011 15.8 4.7 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RmuC PF02646.16 KEY64809.1 - 0.038 13.1 0.1 0.063 12.4 0.1 1.3 1 0 0 1 1 1 0 RmuC family Nup54 PF13874.6 KEY64809.1 - 0.039 14.1 1.0 0.039 14.1 1.0 1.6 2 0 0 2 2 1 0 Nucleoporin complex subunit 54 Laminin_I PF06008.14 KEY64809.1 - 0.06 13.0 2.5 0.095 12.4 2.5 1.3 1 0 0 1 1 1 0 Laminin Domain I Gp-FAR-1 PF05823.12 KEY64809.1 - 0.084 13.2 0.3 0.15 12.4 0.0 1.5 2 0 0 2 2 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) IFT57 PF10498.9 KEY64809.1 - 0.095 11.6 0.6 0.14 11.1 0.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 KEY64809.1 - 0.22 11.5 4.2 13 5.8 0.1 3.0 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 KEY64809.1 - 0.26 10.1 8.4 2.8 6.8 0.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KEY64809.1 - 0.56 9.5 4.2 0.22 10.8 1.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 KEY64809.1 - 0.6 8.4 5.4 1 7.7 5.4 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein YscO PF07321.12 KEY64809.1 - 0.94 9.4 6.6 0.61 10.0 0.6 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO BLOC1_2 PF10046.9 KEY64809.1 - 1.2 9.4 3.2 10 6.5 0.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 KEY64809.1 - 1.3 9.5 9.3 1.4 9.4 1.6 2.4 2 0 0 2 2 2 0 Cell division protein ZapB OEP PF02321.18 KEY64809.1 - 1.5 8.6 7.6 0.075 12.8 2.2 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein SlyX PF04102.12 KEY64809.1 - 1.5 9.5 5.3 29 5.4 2.3 2.8 2 1 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.7 KEY64809.1 - 2.1 8.5 11.5 54 3.9 2.5 2.6 1 1 2 3 3 3 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 KEY64809.1 - 2.5 8.3 6.4 6 7.1 6.4 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 KEY64809.1 - 3.2 8.1 9.5 14 6.0 0.2 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain NCBP3 PF10309.9 KEY64810.1 - 8.7e-24 83.2 0.2 1.6e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KEY64810.1 - 0.21 11.7 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain NAD_binding_1 PF00175.21 KEY64811.1 - 8.4e-07 29.6 0.0 4.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEY64811.1 - 0.00039 20.6 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain SopE_GEF PF07487.13 KEY64811.1 - 0.27 11.3 0.0 0.46 10.6 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain Adaptin_N PF01602.20 KEY64812.1 - 4.7e-142 474.2 0.8 5.6e-142 474.0 0.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KEY64812.1 - 4.5e-22 78.5 1.0 1.2e-21 77.1 0.0 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 KEY64812.1 - 6.8e-08 32.7 4.5 0.00034 20.7 0.0 4.0 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY64812.1 - 2.1e-06 28.0 0.8 0.11 12.9 0.0 4.1 3 2 0 4 4 4 2 HEAT repeats DUF3730 PF12530.8 KEY64812.1 - 7.4e-05 22.4 0.0 0.00031 20.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KEY64812.1 - 0.00021 21.2 1.8 6.7 7.3 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat RICTOR_M PF14666.6 KEY64812.1 - 0.042 13.6 0.4 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain HEAT_EZ PF13513.6 KEY64812.1 - 0.25 11.9 2.3 82 3.9 0.1 4.7 4 2 1 5 5 5 0 HEAT-like repeat EF-hand_1 PF00036.32 KEY64813.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEY64813.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEY64813.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KEY64813.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEY64813.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KEY64813.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KEY64813.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KEY64813.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KEY64813.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KEY64813.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KEY64813.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KEY64813.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KEY64813.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KEY64813.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 KEY64813.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 KEY64813.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KEY64813.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KEY64813.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KEY64813.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KEY64813.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KEY64813.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 KEY64813.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KEY64813.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KEY64813.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 KEY64813.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 KEY64813.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 KEY64814.1 - 1.1e-15 57.4 0.1 3e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KEY64814.1 - 7.6e-05 22.5 11.6 0.00083 19.1 11.6 2.1 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KEY64814.1 - 0.023 15.1 11.5 0.046 14.1 3.2 2.5 3 0 0 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.21 KEY64814.1 - 0.026 14.3 8.5 0.22 11.3 0.5 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dad4 PF08650.10 KEY64814.1 - 0.049 13.6 0.4 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 DNA_repr_REX1B PF14966.6 KEY64814.1 - 0.2 12.4 2.7 0.21 12.3 0.3 2.3 2 1 0 2 2 2 0 DNA repair REX1-B GCP_C_terminal PF04130.13 KEY64814.1 - 0.37 10.2 3.2 0.29 10.6 0.8 1.8 1 1 0 2 2 2 0 Gamma tubulin complex component C-terminal MutS_III PF05192.18 KEY64814.1 - 0.55 10.4 3.2 0.93 9.7 3.1 1.4 1 1 0 1 1 1 0 MutS domain III DUF4477 PF14780.6 KEY64815.1 - 0.16 11.6 0.2 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) DDE_Tnp_IS66 PF03050.14 KEY64815.1 - 0.27 10.6 2.0 23 4.3 0.0 3.6 4 0 0 4 4 4 0 Transposase IS66 family COX7a PF02238.15 KEY64816.1 - 4.6e-21 75.0 1.6 5.3e-21 74.8 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII LPG_synthase_TM PF03706.13 KEY64816.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Clathrin_lg_ch PF01086.17 KEY64817.1 - 9.9e-74 248.3 4.2 1.1e-73 248.1 4.2 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF5630 PF18632.1 KEY64817.1 - 0.27 10.5 3.6 0.38 10.0 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5630) CTD_bind PF04818.13 KEY64818.1 - 1.9e-17 63.8 0.3 7.2e-17 62.0 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Antimicrobial10 PF08105.11 KEY64818.1 - 0.013 15.6 0.2 0.048 13.7 0.2 2.0 1 0 0 1 1 1 0 Metchnikowin family DHR10 PF18595.1 KEY64818.1 - 0.028 14.5 1.5 0.028 14.5 1.5 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Transcrip_act PF04949.13 KEY64818.1 - 0.041 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator ABC_membrane PF00664.23 KEY64819.1 - 7e-50 170.2 9.9 9.4e-50 169.8 9.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEY64819.1 - 9.5e-34 116.8 0.2 3.7e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KEY64819.1 - 0.00042 19.8 0.0 0.013 14.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEY64819.1 - 0.0018 18.6 0.1 0.012 15.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY64819.1 - 0.008 16.6 0.1 0.025 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEY64819.1 - 0.011 16.1 0.3 0.12 12.8 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY64819.1 - 0.022 14.8 0.1 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEY64819.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEY64819.1 - 0.045 14.0 1.3 1 9.6 1.3 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEY64819.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KEY64819.1 - 0.15 11.7 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein CcdA PF07362.12 KEY64819.1 - 0.75 10.3 2.8 9.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Hydrolase_4 PF12146.8 KEY64820.1 - 3.1e-48 164.1 0.1 3.6e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY64820.1 - 5.3e-14 53.4 2.7 6.7e-14 53.0 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY64820.1 - 2.6e-11 43.7 0.3 1.2e-10 41.4 0.1 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KEY64820.1 - 0.0058 15.7 0.0 0.0082 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KEY64820.1 - 0.0072 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 KEY64820.1 - 0.041 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Cation_efflux PF01545.21 KEY64821.1 - 1.9e-15 57.1 8.9 2.5e-15 56.8 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEY64821.1 - 3.5e-10 39.9 0.1 7.3e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Glyco_transf_8 PF01501.20 KEY64822.1 - 4.9e-22 78.7 0.4 1e-20 74.4 0.4 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KEY64822.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative zf-rbx1 PF12678.7 KEY64823.1 - 2e-09 37.6 5.6 2e-09 37.6 5.6 1.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEY64823.1 - 3.6e-08 33.6 6.2 8.3e-08 32.5 6.2 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEY64823.1 - 1.7e-05 24.8 2.8 3.3e-05 23.8 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEY64823.1 - 2.1e-05 24.4 1.7 5.1e-05 23.1 1.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KEY64823.1 - 2.6e-05 24.0 3.9 4.6e-05 23.2 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY64823.1 - 3.2e-05 23.7 5.5 0.00025 20.8 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEY64823.1 - 0.00017 21.6 0.7 0.00053 20.0 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KEY64823.1 - 0.00063 19.3 0.2 0.0014 18.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KEY64823.1 - 0.0015 18.3 2.4 0.0015 18.3 2.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY64823.1 - 0.0042 16.9 5.6 0.022 14.6 5.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEY64823.1 - 0.13 12.5 1.0 0.27 11.4 1.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KEY64823.1 - 0.52 10.1 3.1 0.4 10.5 0.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KEY64823.1 - 0.91 9.3 2.3 8 6.3 2.3 2.2 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KEY64823.1 - 1.3 9.3 3.6 3.1 8.1 2.4 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C2H2 PF00096.26 KEY64826.1 - 3.8e-05 23.9 17.4 0.32 11.5 0.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2HE PF16278.5 KEY64826.1 - 0.016 15.7 1.0 0.71 10.4 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Pox_G9-A16 PF03003.16 KEY64826.1 - 0.063 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 zf-C2H2_4 PF13894.6 KEY64826.1 - 0.075 13.9 19.3 1 10.4 0.4 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger SAT PF16073.5 KEY64826.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis zf-TAZ PF02135.16 KEY64826.1 - 0.092 13.2 4.4 0.22 12.0 2.6 2.2 2 0 0 2 2 2 0 TAZ zinc finger FOXP-CC PF16159.5 KEY64826.1 - 0.17 12.5 3.9 3.2 8.5 0.7 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain RPN2_C PF18004.1 KEY64827.1 - 0.28 11.1 4.9 0.63 9.9 4.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FixS PF03597.15 KEY64827.1 - 9.8 6.0 6.0 22 4.9 6.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type YdfA_immunity PF12127.8 KEY64828.1 - 0.042 12.9 4.8 0.061 12.4 4.8 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Exo_endo_phos PF03372.23 KEY64829.1 - 8.4e-08 32.0 0.3 1.5e-07 31.2 0.3 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family V-SNARE_C PF12352.8 KEY64830.1 - 0.033 14.5 2.5 0.046 14.0 0.5 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus bZIP_1 PF00170.21 KEY64831.1 - 3.3e-06 27.1 6.1 3.3e-06 27.1 6.1 1.9 2 0 0 2 2 2 1 bZIP transcription factor Nop53 PF07767.11 KEY64831.1 - 0.0038 16.7 10.3 0.57 9.5 6.1 2.1 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 KEY64831.1 - 0.047 13.0 1.6 0.83 9.0 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5595 PF18077.1 KEY64831.1 - 0.12 12.5 3.5 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Vir_act_alpha_C PF10400.9 KEY64831.1 - 0.18 12.5 3.0 6.3 7.6 2.9 2.7 3 0 0 3 3 3 0 Virulence activator alpha C-term bZIP_2 PF07716.15 KEY64831.1 - 0.78 9.9 10.5 0.18 11.9 6.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_16 PF00722.21 KEY64832.1 - 1.4e-11 44.2 1.0 1.9e-11 43.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.26 KEY64833.1 - 3.5e-09 36.6 2.5 8.5e-09 35.4 2.5 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KEY64833.1 - 0.044 14.1 0.4 0.12 12.7 0.4 1.7 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f RIX1 PF08167.12 KEY64834.1 - 1.5e-57 194.4 1.6 3.1e-57 193.4 1.6 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.17 KEY64835.1 - 2.1e-08 33.7 11.3 0.39 11.0 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY64835.1 - 4.2e-08 33.3 23.1 0.12 13.2 0.7 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEY64835.1 - 9.5e-05 22.1 9.7 2 8.4 0.4 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY64835.1 - 0.0052 17.1 6.0 0.75 10.3 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY64835.1 - 0.015 15.4 12.9 0.7 10.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY64835.1 - 0.025 15.2 23.5 7.1 7.4 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 KEY64835.1 - 0.044 13.5 1.1 21 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KEY64835.1 - 0.87 10.4 7.5 12 6.8 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF737 PF05300.11 KEY64836.1 - 0.0092 16.4 3.0 0.0092 16.4 3.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF737) CdiI_2 PF18593.1 KEY64836.1 - 0.069 13.8 0.1 0.32 11.7 0.0 2.2 2 0 0 2 2 2 0 CdiI immunity protein Miga PF10265.9 KEY64836.1 - 1.1 8.2 3.5 1.6 7.6 3.5 1.3 1 1 0 1 1 1 0 Mitoguardin Xpo1 PF08389.12 KEY64837.1 - 2.3e-34 118.6 0.1 1.7e-33 115.8 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 KEY64837.1 - 0.0009 19.3 0.1 7 7.2 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat CHAD PF05235.14 KEY64837.1 - 0.11 12.4 0.0 0.48 10.4 0.0 2.1 1 1 0 1 1 1 0 CHAD domain Iso_dh PF00180.20 KEY64839.1 - 5.1e-128 427.1 0.0 6e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RTA1 PF04479.13 KEY64840.1 - 5.8e-69 231.8 12.9 8.3e-69 231.3 12.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Cytochrom_B558a PF05038.13 KEY64840.1 - 0.13 11.8 5.8 0.064 12.8 2.5 2.0 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Peptidase_M18 PF02127.15 KEY64841.1 - 2.1e-173 577.1 0.0 5.2e-173 575.8 0.0 1.5 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KEY64841.1 - 3e-05 23.2 0.0 0.00048 19.2 0.0 2.5 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Whi5 PF08528.11 KEY64842.1 - 2.1e-09 36.8 0.1 3.4e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Whi5 like KIX_2 PF16987.5 KEY64843.1 - 0.0058 16.6 0.2 0.0058 16.6 0.2 4.2 4 1 1 5 5 5 1 KIX domain Aldedh PF00171.22 KEY64846.1 - 3.3e-164 546.8 0.0 4e-164 546.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family bZIP_2 PF07716.15 KEY64847.1 - 0.023 14.8 12.9 0.035 14.2 12.9 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KEY64847.1 - 0.025 14.7 10.9 0.038 14.1 10.9 1.2 1 0 0 1 1 1 0 bZIP transcription factor EURL PF06937.11 KEY64847.1 - 0.35 10.3 2.7 0.53 9.7 2.7 1.1 1 0 0 1 1 1 0 EURL protein Phlebovirus_NSM PF07246.11 KEY64847.1 - 0.65 9.3 3.3 1 8.7 3.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PNP_UDP_1 PF01048.20 KEY64848.1 - 1e-12 47.8 0.0 2.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.6 KEY64848.1 - 1.1e-12 48.0 0.2 5.4e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY64848.1 - 2.5e-09 36.7 0.2 9.4e-05 22.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEY64848.1 - 6.4e-06 25.5 0.0 0.015 14.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 KEY64848.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.6 KEY64848.1 - 0.0041 17.1 0.3 0.049 13.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY64848.1 - 0.011 16.2 0.1 0.7 10.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1541 PF07563.11 KEY64848.1 - 0.019 14.8 0.2 0.045 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) TPR_2 PF07719.17 KEY64848.1 - 0.048 13.8 0.9 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.11 KEY64849.1 - 8.7e-14 52.1 1.2 2.3e-13 50.7 1.2 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CPL PF08144.11 KEY64849.1 - 0.00016 22.0 4.5 15 5.9 0.0 5.8 1 1 4 6 6 6 2 CPL (NUC119) domain TPR_12 PF13424.6 KEY64849.1 - 0.002 18.4 0.1 0.0074 16.6 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF1241 PF06840.11 KEY64849.1 - 0.03 14.0 2.5 20 4.8 0.1 4.6 1 1 4 6 6 6 0 Protein of unknown function (DUF1241) KOW PF00467.29 KEY64849.1 - 3.2 7.8 6.9 2.5e+02 1.8 0.0 5.7 7 0 0 7 7 7 0 KOW motif F-box-like PF12937.7 KEY64850.1 - 0.038 13.9 1.9 0.088 12.7 1.9 1.7 1 0 0 1 1 1 0 F-box-like DUF1635 PF07795.11 KEY64851.1 - 0.048 13.5 0.3 0.053 13.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-C2H2 PF00096.26 KEY64852.1 - 1.9e-05 24.9 7.4 0.059 13.8 0.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY64852.1 - 0.094 13.2 4.9 0.62 10.6 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_L35p PF01632.19 KEY64852.1 - 0.18 12.4 0.1 0.36 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L35 Zn_ribbon_SprT PF17283.2 KEY64852.1 - 0.75 9.7 3.1 0.85 9.6 0.1 2.7 4 0 0 4 4 4 0 SprT-like zinc ribbon domain Pkinase PF00069.25 KEY64854.1 - 3.4e-21 75.8 0.0 4.7e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY64854.1 - 3.4e-09 36.4 0.0 6.5e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY64854.1 - 2.3e-08 33.3 0.0 3.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEY64854.1 - 0.0011 19.0 0.0 0.026 14.5 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY64854.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_Tnp_1_7 PF13843.6 KEY64856.1 - 1.7e-37 129.6 0.0 2.5e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KEY64856.1 - 0.0011 19.7 5.1 0.0011 19.7 5.1 2.4 3 0 0 3 3 3 1 DDE_Tnp_1-like zinc-ribbon zf-C4pol PF14260.6 KEY64856.1 - 0.76 10.3 5.2 1 9.9 2.3 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta APH PF01636.23 KEY64858.1 - 0.0003 20.8 0.0 0.00042 20.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY64859.1 - 1.8e-51 175.2 0.0 9.6e-40 136.6 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase AAA PF00004.29 KEY64860.1 - 2.7e-18 66.6 0.0 6.4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY64860.1 - 0.00024 21.1 0.2 0.00088 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEY64860.1 - 0.0012 19.3 3.9 0.016 15.6 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KEY64860.1 - 0.0012 19.1 0.2 0.02 15.2 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KEY64860.1 - 0.0091 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEY64860.1 - 0.035 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEY64860.1 - 0.048 14.0 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KEY64860.1 - 0.054 12.9 0.1 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KEY64860.1 - 0.13 12.7 0.1 0.55 10.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KEY64860.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KEY64860.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_39 PF14090.6 KEY64861.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 KEY64863.1 - 1.2e-09 38.0 0.1 1.8e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEY64863.1 - 1.6e-05 25.0 0.0 0.00035 20.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KEY64863.1 - 2.7e-05 23.6 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KEY64863.1 - 2.8e-05 23.8 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEY64863.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEY64863.1 - 0.006 16.2 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase ZirS_C PF16583.5 KEY64863.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Pkinase_fungal PF17667.1 KEY64863.1 - 0.039 12.7 0.1 0.054 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEY64863.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pectate_lyase PF03211.13 KEY64865.1 - 5.8e-84 280.7 7.9 6.7e-84 280.5 7.9 1.0 1 0 0 1 1 1 1 Pectate lyase DUF3682 PF12446.8 KEY64865.1 - 0.12 12.9 0.7 0.25 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) OST3_OST6 PF04756.13 KEY64866.1 - 0.0055 16.1 0.4 0.0083 15.5 0.4 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4233 PF14017.6 KEY64866.1 - 4.8 7.6 12.5 0.26 11.6 2.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) RAI16-like PF10257.9 KEY64867.1 - 2e-71 240.8 2.3 3.1e-71 240.1 2.3 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Proteasom_PSMB PF10508.9 KEY64867.1 - 0.088 11.3 0.5 0.16 10.5 0.5 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Dynamin_N PF00350.23 KEY64868.1 - 4.2e-13 49.7 0.1 2e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEY64868.1 - 2.7e-06 27.4 0.0 0.0011 19.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEY64868.1 - 0.00015 22.3 0.1 0.00075 20.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KEY64868.1 - 0.00088 19.2 0.0 0.0032 17.4 0.0 2.0 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KEY64868.1 - 0.026 14.7 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KEY64868.1 - 0.028 14.7 0.0 0.98 9.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEY64868.1 - 0.05 14.0 0.0 0.47 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KEY64868.1 - 0.06 13.4 0.1 0.06 13.4 0.1 3.8 3 1 0 4 4 4 0 Helicase HerA, central domain KinB_sensor PF16767.5 KEY64868.1 - 0.41 11.1 4.8 0.62 10.5 0.1 3.4 3 1 0 4 4 4 0 Sensor domain of alginate biosynthesis sensor protein KinB Thioesterase PF00975.20 KEY64869.1 - 2.5e-11 44.1 0.0 2e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEY64869.1 - 7.4e-06 26.7 0.2 1e-05 26.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KEY64869.1 - 0.014 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEY64869.1 - 0.055 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold CLP_protease PF00574.23 KEY64870.1 - 8.8e-69 231.0 0.4 1.2e-68 230.6 0.4 1.1 1 0 0 1 1 1 1 Clp protease GTP_cyclohydro2 PF00925.20 KEY64870.1 - 0.0027 17.3 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II ILVD_EDD PF00920.21 KEY64872.1 - 4.4e-215 715.2 0.6 5.1e-215 715.0 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family Acyltransferase PF01553.21 KEY64873.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase DUF413 PF04219.12 KEY64873.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Kinesin PF00225.23 KEY64874.1 - 1.2e-104 349.9 1.3 2.6e-104 348.7 1.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEY64874.1 - 9.8e-56 187.8 0.0 2.3e-55 186.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KEY64874.1 - 2.4e-05 23.3 18.7 2.4e-05 23.3 18.7 2.6 2 1 1 3 3 3 1 Weak chloroplast movement under blue light AAA_16 PF13191.6 KEY64874.1 - 0.086 13.2 0.0 0.086 13.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain KASH_CCD PF14662.6 KEY64874.1 - 2.6 7.8 42.2 0.11 12.3 5.4 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KEY64874.1 - 2.8 8.1 26.3 0.28 11.3 0.4 4.7 2 1 2 4 4 4 0 bZIP transcription factor Baculo_PEP_C PF04513.12 KEY64874.1 - 3.7 7.6 7.2 11 6.0 1.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KEY64874.1 - 4.9 7.5 33.2 7.7 6.9 13.4 3.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KEY64874.1 - 6.9 6.7 16.9 3.1 7.8 3.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 KEY64874.1 - 8.1 6.7 6.7 1.2 9.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain HhH-GPD PF00730.25 KEY64876.1 - 7.2e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEY64876.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ndc1_Nup PF09531.10 KEY64876.1 - 5.3 5.6 5.4 7.2 5.2 5.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 5_nucleotid_C PF02872.18 KEY64878.1 - 1.2e-33 116.6 0.0 2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KEY64878.1 - 3.2e-15 57.2 0.2 4.8e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KEY64878.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein DUF5026 PF16429.5 KEY64878.1 - 0.095 12.8 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) MFS_1 PF07690.16 KEY64879.1 - 3e-43 148.1 54.7 3.6e-36 124.8 33.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.21 KEY64880.1 - 4.3e-25 87.9 0.0 6.2e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KEY64880.1 - 7.2e-12 45.2 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus 7TM_GPCR_Srt PF10321.9 KEY64880.1 - 0.015 14.3 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt NAD_kinase PF01513.21 KEY64881.1 - 8e-43 146.7 0.0 1.8e-42 145.5 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KEY64881.1 - 0.057 13.0 0.2 1.7 8.3 0.3 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PLA2_B PF01735.18 KEY64883.1 - 1.5e-175 584.3 0.0 1.8e-175 584.1 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain GFO_IDH_MocA PF01408.22 KEY64884.1 - 7.9e-20 71.9 0.0 1.5e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEY64884.1 - 4.7e-12 45.9 0.0 9.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KEY64884.1 - 0.0021 18.7 0.0 0.0045 17.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peptidase_M28 PF04389.17 KEY64885.1 - 1.9e-34 119.1 0.0 3.5e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY64885.1 - 0.00052 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KEY64885.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase SF1-HH PF16275.5 KEY64886.1 - 2.9e-43 146.8 1.4 2.9e-43 146.8 1.4 1.7 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain MFS_1 PF07690.16 KEY64886.1 - 6.6e-32 110.8 26.0 8.8e-32 110.4 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCHC PF00098.23 KEY64886.1 - 7.4e-11 41.6 11.3 2.8e-05 24.0 0.8 2.5 2 0 0 2 2 2 2 Zinc knuckle MFS_4 PF06779.14 KEY64886.1 - 5.9e-09 35.7 14.0 5.9e-07 29.1 2.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB KH_1 PF00013.29 KEY64886.1 - 6.7e-08 32.3 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KEY64886.1 - 4.2e-06 26.6 6.4 0.0011 18.9 3.0 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KEY64886.1 - 0.0048 16.7 7.9 0.33 10.8 0.5 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KEY64886.1 - 0.0063 16.2 5.0 1.2 8.9 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KEY64886.1 - 0.03 14.2 0.5 0.03 14.2 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle TssN PF17555.2 KEY64886.1 - 1.6 8.0 3.7 3.9 6.8 3.7 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN Lipase_3 PF01764.25 KEY64887.1 - 1.1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF515 PF04415.12 KEY64887.1 - 4.3 5.6 17.7 7.1 4.9 17.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.9 KEY64887.1 - 6.6 5.1 10.5 13 4.2 10.5 1.4 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 KEY64889.1 - 0.82 9.8 10.3 1.7 8.8 10.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KEY64890.1 - 2e-23 83.5 0.0 3e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEY64890.1 - 0.0009 18.4 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.18 KEY64891.1 - 3.2e-10 39.9 10.6 5e-10 39.3 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY64891.1 - 4e-08 32.6 2.3 9.4e-08 31.4 2.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 KEY64892.1 - 9.8e-07 28.5 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 KEY64893.1 - 4.3e-33 113.7 0.0 5.7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family BAR PF03114.18 KEY64894.1 - 3.3e-65 220.1 2.9 4.1e-65 219.8 2.9 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KEY64894.1 - 0.0051 17.5 0.0 0.021 15.5 0.0 2.1 2 1 1 3 3 3 1 CP12 domain Pept_tRNA_hydro PF01195.19 KEY64895.1 - 1.3e-30 106.6 0.0 1.7e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF4726 PF15855.5 KEY64895.1 - 0.12 12.6 0.1 9.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Ammonium_transp PF00909.21 KEY64896.1 - 9.6e-117 390.0 24.5 1.1e-116 389.8 24.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family F-box-like PF12937.7 KEY64898.1 - 8.6e-13 48.0 4.7 1.3e-12 47.4 1.3 2.9 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.6 KEY64898.1 - 3.5e-12 45.3 24.5 0.7 10.1 0.0 11.4 13 0 0 13 13 13 5 Leucine Rich repeat LRR_4 PF12799.7 KEY64898.1 - 3.3e-09 36.9 15.2 1.6 9.2 0.0 7.4 5 3 4 9 9 9 6 Leucine Rich repeats (2 copies) F-box PF00646.33 KEY64898.1 - 8.9e-07 28.6 1.8 3.5e-06 26.7 1.8 2.1 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 KEY64898.1 - 0.0036 17.0 0.4 8 6.2 0.0 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF1699) Chalcone_2 PF16035.5 KEY64899.1 - 1.3e-75 253.7 0.0 2.2e-75 253.0 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KEY64899.1 - 1.9e-05 24.8 0.1 0.0065 16.6 0.1 2.5 1 1 1 2 2 2 2 Chalcone isomerase-like Glutaredoxin PF00462.24 KEY64900.1 - 3.6e-20 71.9 0.0 6.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KEY64900.1 - 0.0037 17.7 0.0 0.0064 16.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 KEY64900.1 - 0.0039 17.6 0.0 0.0047 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY64900.1 - 0.005 17.1 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 KEY64900.1 - 0.0057 17.0 0.0 0.0086 16.5 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) THF_DHG_CYH PF00763.23 KEY64900.1 - 0.039 14.2 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DSBA PF01323.20 KEY64900.1 - 0.21 11.3 0.6 2.3 8.0 0.4 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KEY64900.1 - 0.21 11.7 0.5 2.9 8.0 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin BAG PF02179.16 KEY64901.1 - 1e-19 70.7 0.4 2.2e-19 69.7 0.4 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KEY64901.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KEY64901.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KEY64901.1 - 0.038 14.3 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KEY64901.1 - 0.11 13.0 0.2 0.24 12.0 0.2 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L13 PF00572.18 KEY64902.1 - 4e-12 46.5 0.0 4.2e-10 39.9 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 TPR_2 PF07719.17 KEY64903.1 - 9.6e-10 37.8 5.1 2.3e-05 24.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY64903.1 - 2.9e-08 33.2 1.8 0.0018 18.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY64903.1 - 6.2e-06 26.6 1.7 0.00027 21.4 1.7 2.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY64903.1 - 2.2e-05 24.6 3.3 0.032 14.5 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY64903.1 - 5.5e-05 23.1 1.2 0.00088 19.3 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY64903.1 - 0.00019 22.0 5.1 0.092 13.4 2.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEY64903.1 - 0.00027 20.6 0.1 0.015 15.0 0.1 2.8 2 1 1 3 3 3 1 TPR repeat SPO22 PF08631.10 KEY64903.1 - 0.061 12.8 0.0 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 KEY64903.1 - 0.063 14.1 5.7 0.11 13.3 0.6 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY64903.1 - 0.074 13.7 2.5 1.2 9.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY64903.1 - 0.087 12.9 1.1 4.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY64903.1 - 0.32 10.9 5.0 13 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Lyase_1 PF00206.20 KEY64905.1 - 2.5e-19 69.8 0.2 3.8e-19 69.2 0.2 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KEY64905.1 - 3.9e-14 52.9 0.0 1.5e-13 51.1 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Skp1 PF01466.19 KEY64905.1 - 0.5 10.5 5.3 13 6.0 0.1 3.2 4 0 0 4 4 4 0 Skp1 family, dimerisation domain Cupin_2 PF07883.11 KEY64906.1 - 0.00017 21.2 0.2 0.00033 20.3 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.21 KEY64907.1 - 2.4e-10 40.3 0.3 0.00039 20.0 0.2 2.6 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY64907.1 - 2.3e-09 37.4 0.4 3.5e-09 36.8 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY64907.1 - 4.8e-07 29.6 0.2 9e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KEY64907.1 - 0.00073 20.0 0.1 0.0016 18.9 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KEY64907.1 - 0.00083 18.6 0.0 0.0033 16.7 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KEY64907.1 - 0.00093 19.5 0.1 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KEY64907.1 - 0.0038 16.3 0.1 0.056 12.4 0.1 2.4 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family CNTF PF01110.17 KEY64907.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor Polysacc_synt_2 PF02719.15 KEY64907.1 - 0.19 10.8 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldedh PF00171.22 KEY64908.1 - 7.5e-181 601.7 0.5 8.5e-181 601.5 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AraC_binding PF02311.19 KEY64909.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Adap_comp_sub PF00928.21 KEY64910.1 - 2.6e-83 279.4 0.0 3.3e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEY64910.1 - 5e-05 23.3 0.2 8.8e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KEY64910.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Glyco_hydro_6 PF01341.17 KEY64911.1 - 2.3e-104 349.4 0.1 3e-104 349.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KEY64911.1 - 2e-11 43.6 13.2 7.6e-11 41.8 13.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain PLDc_2 PF13091.6 KEY64913.1 - 2.9e-20 72.5 0.0 6.3e-13 48.8 0.0 3.4 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KEY64913.1 - 0.012 15.7 0.2 0.73 10.1 0.1 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KEY64913.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DSBA PF01323.20 KEY64914.1 - 1.4e-25 90.2 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KEY64914.1 - 0.053 13.7 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Fungal_trans_2 PF11951.8 KEY64915.1 - 1.6e-24 86.4 1.3 1.7e-12 46.8 1.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF1996 PF09362.10 KEY64916.1 - 0.0012 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NepR PF18557.1 KEY64916.1 - 0.023 14.3 1.0 0.023 14.3 1.0 2.6 3 0 0 3 3 3 0 Anti-sigma factor NepR DP PF08781.10 KEY64916.1 - 0.17 11.8 2.4 0.41 10.5 2.4 1.6 1 0 0 1 1 1 0 Transcription factor DP DUF948 PF06103.11 KEY64916.1 - 3.5 8.0 7.0 14 6.0 2.5 3.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 KEY64916.1 - 9.6 6.8 10.1 1.3 9.6 0.9 2.7 2 2 1 3 3 3 0 Protein of unknown function DUF16 Glyco_hydro_43 PF04616.14 KEY64917.1 - 8.9e-39 133.5 2.2 1e-38 133.3 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 KEY64918.1 - 1.2e-40 139.7 0.5 1.5e-40 139.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 KEY64918.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat Jnk-SapK_ap_N PF09744.9 KEY64919.1 - 0.17 12.1 9.4 0.3 11.3 9.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HSP70 PF00012.20 KEY64920.1 - 2.1e-08 32.9 0.0 4e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY64920.1 - 0.00036 19.5 0.1 0.0017 17.2 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Dynamin_N PF00350.23 KEY64921.1 - 1.7e-65 220.2 0.1 6.6e-33 114.1 0.1 2.6 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.20 KEY64921.1 - 3.2e-50 171.0 0.0 1.2e-25 90.4 0.0 4.3 3 1 0 3 3 3 3 Dynamin central region MMR_HSR1 PF01926.23 KEY64921.1 - 2.6e-08 33.9 1.0 0.0051 16.9 0.1 4.2 2 2 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.18 KEY64921.1 - 3.8e-07 30.1 1.9 0.0021 18.1 0.1 3.6 3 1 0 3 3 3 2 Dynamin GTPase effector domain Roc PF08477.13 KEY64921.1 - 0.00062 20.0 0.0 0.79 10.0 0.0 3.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEY64921.1 - 0.0011 18.5 0.1 25 4.4 0.0 4.2 4 0 0 4 4 4 0 Ferrous iron transport protein B AAA_29 PF13555.6 KEY64921.1 - 0.0084 15.8 0.0 13 5.7 0.0 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEY64921.1 - 0.011 16.2 0.0 3.1 8.3 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_15 PF13175.6 KEY64921.1 - 0.035 13.8 0.0 9.1 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KEY64921.1 - 0.06 12.9 0.0 9.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Ras family AAA_21 PF13304.6 KEY64921.1 - 0.11 12.3 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEY64921.1 - 0.11 12.9 6.0 0.63 10.4 0.0 3.8 3 1 1 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 KEY64921.1 - 0.61 10.5 4.2 97 3.4 0.0 3.8 2 1 0 2 2 2 0 AAA domain OTT_1508_deam PF14441.6 KEY64922.1 - 1.1e-15 57.4 0.1 2.1e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 KEY64922.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Dynamin_N PF00350.23 KEY64923.1 - 3.8e-30 105.2 0.0 9.7e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEY64923.1 - 3.7e-23 82.2 0.6 9.1e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KEY64923.1 - 1.2e-05 25.4 0.1 0.00023 21.2 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KEY64923.1 - 0.00018 21.6 0.1 0.0018 18.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KEY64923.1 - 0.021 15.4 0.0 0.11 13.0 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_15 PF13175.6 KEY64923.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KEY64923.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ADH_zinc_N PF00107.26 KEY64924.1 - 1.5e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY64924.1 - 2.4e-05 24.2 0.0 0.00013 21.8 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 KEY64925.1 - 0.00018 21.5 10.1 0.00029 20.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_4 PF13418.6 KEY64926.1 - 1.4e-25 89.0 5.7 1.3e-10 41.1 0.0 5.7 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY64926.1 - 2.8e-19 68.9 4.0 0.00012 22.3 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KEY64926.1 - 1.7e-17 62.8 9.7 0.00013 21.5 0.2 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KEY64926.1 - 1.2e-11 44.4 7.1 0.0061 16.8 0.1 5.4 3 1 2 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KEY64926.1 - 5.8e-11 42.1 1.6 0.0042 17.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KEY64926.1 - 2.4e-10 40.0 12.8 0.002 18.1 0.2 4.8 3 1 1 4 4 4 4 Kelch motif Aldedh PF00171.22 KEY64927.1 - 8.2e-135 449.9 0.2 1e-134 449.5 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEY64927.1 - 0.054 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.18 KEY64928.1 - 3.4e-167 555.9 17.2 4.3e-167 555.6 17.2 1.1 1 0 0 1 1 1 1 Calreticulin family SseC PF04888.12 KEY64928.1 - 0.0033 17.1 1.8 0.0055 16.3 1.8 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family OAD_gamma PF04277.13 KEY64928.1 - 0.74 10.5 3.8 1.8 9.2 0.6 3.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain OATP PF03137.20 KEY64929.1 - 1.1 7.4 3.5 1.5 7.0 3.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2613 PF11021.8 KEY64929.1 - 1.6 8.9 7.1 0.2 11.8 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Aldolase_II PF00596.21 KEY64930.1 - 3.5e-40 137.9 0.0 4.3e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sec20 PF03908.13 KEY64931.1 - 1.4e-12 47.4 0.2 4e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Sec20 MRP_L53 PF10780.9 KEY64932.1 - 1.9e-20 72.7 0.4 2.7e-20 72.3 0.4 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.13 KEY64932.1 - 0.024 14.6 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Ecotin KorB_C PF06613.11 KEY64932.1 - 0.031 14.2 0.0 2 8.4 0.0 2.1 1 1 1 2 2 2 0 KorB C-terminal beta-barrel domain DUF971 PF06155.12 KEY64932.1 - 0.17 12.5 0.0 0.31 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pyrophosphatase PF00719.19 KEY64933.1 - 3.3e-58 196.0 0.1 4.8e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MAP65_ASE1 PF03999.12 KEY64933.1 - 1.6 7.3 7.9 2.1 7.0 7.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pil1 PF13805.6 KEY64934.1 - 9.8e-106 353.1 4.7 1.3e-105 352.7 4.7 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Ribophorin_I PF04597.14 KEY64935.1 - 3e-147 491.4 0.3 3.4e-147 491.2 0.3 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 KEY64936.1 - 2.6e-82 275.9 0.0 3.4e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEY64936.1 - 2.2e-70 236.6 0.0 4e-70 235.8 0.0 1.4 2 0 0 2 2 2 1 Hexokinase VTC PF09359.10 KEY64938.1 - 5.7e-95 317.8 0.0 8.4e-95 317.3 0.0 1.3 1 0 0 1 1 1 1 VTC domain Cys_Met_Meta_PP PF01053.20 KEY64938.1 - 1e-22 80.2 0.0 1.5e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF202 PF02656.15 KEY64938.1 - 1.3e-11 44.7 1.7 3.2e-11 43.5 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KEY64938.1 - 5.3e-09 36.5 7.5 0.0022 18.0 0.0 3.5 3 1 1 4 4 4 3 SPX domain Aminotran_1_2 PF00155.21 KEY64938.1 - 0.00019 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II MCM PF00493.23 KEY64939.1 - 5.3e-101 336.4 0.0 8.7e-101 335.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEY64939.1 - 4.3e-39 133.2 0.6 7.5e-39 132.4 0.6 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEY64939.1 - 1.3e-28 99.3 4.2 2.8e-28 98.2 4.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY64939.1 - 6.8e-15 55.5 0.1 3.4e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KEY64939.1 - 2e-05 24.6 0.1 0.00025 21.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEY64939.1 - 8.6e-05 22.0 0.0 0.00069 19.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEY64939.1 - 0.0027 17.5 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 KEY64939.1 - 0.038 13.6 0.1 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 GGA N-GAT domain Clat_adaptor_s PF01217.20 KEY64940.1 - 5.3e-15 55.6 0.8 3e-14 53.1 0.8 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_129 PF11308.8 KEY64940.1 - 0.092 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Sua5_yciO_yrdC PF01300.18 KEY64941.1 - 8e-54 181.8 0.0 1.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KEY64941.1 - 3.2e-30 105.4 0.0 4.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.12 KEY64942.1 - 1.3e-123 412.4 0.0 1.7e-123 412.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.20 KEY64942.1 - 1.4e-45 155.1 0.8 4e-45 153.6 0.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY64942.1 - 1.5e-39 135.6 0.5 3.3e-39 134.5 0.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY64942.1 - 1.9e-19 70.8 4.2 6.8e-19 69.0 2.4 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY64942.1 - 6.8e-19 67.3 0.0 1.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEY64942.1 - 1.4e-14 53.9 0.0 3.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY64942.1 - 0.00021 21.1 0.5 0.00091 19.0 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY64942.1 - 0.067 13.6 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 KEY64943.1 - 4.3e-31 107.3 0.1 9.9e-31 106.2 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KEY64943.1 - 1.7e-08 33.6 0.0 4.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TBCA PF02970.16 KEY64944.1 - 2.7e-21 75.7 10.2 5.8e-21 74.6 9.3 1.8 1 1 1 2 2 2 1 Tubulin binding cofactor A APC_N_CC PF16689.5 KEY64944.1 - 0.043 13.9 0.2 0.043 13.9 0.2 2.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Phage_GP20 PF06810.11 KEY64944.1 - 0.047 13.5 10.4 0.9 9.3 3.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 eIF3_N PF09440.10 KEY64944.1 - 1.4 9.3 6.2 2.5 8.6 1.3 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain SlyX PF04102.12 KEY64944.1 - 2.5 8.8 7.6 1.5 9.5 2.6 2.4 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 KEY64944.1 - 3.7 7.9 14.3 0.61 10.4 10.2 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 KEY64945.1 - 5.2e-44 149.7 5.9 5.2e-44 149.7 5.9 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 KEY64945.1 - 0.021 13.4 4.2 0.027 13.0 4.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 KEY64945.1 - 2.9 8.2 9.7 2.8 8.3 8.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-CCCH PF00642.24 KEY64946.1 - 9.3e-05 22.2 0.1 9.3e-05 22.2 0.1 4.5 3 1 1 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEY64946.1 - 0.00096 18.9 0.2 0.00096 18.9 0.2 4.1 4 0 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEY64946.1 - 0.001 19.0 1.7 0.001 19.0 1.7 4.6 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 KEY64946.1 - 0.33 11.7 18.0 1 10.1 2.8 3.7 1 1 2 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 KEY64946.1 - 0.46 10.7 14.0 0.23 11.7 1.5 3.1 2 1 0 2 2 2 0 Zinc-finger containing family SDA1 PF05285.12 KEY64946.1 - 3.6 6.9 9.3 0.37 10.2 2.2 2.0 2 0 0 2 2 2 0 SDA1 Sel1 PF08238.12 KEY64947.1 - 0.021 15.5 0.0 3.7 8.4 0.1 3.1 3 0 0 3 3 3 0 Sel1 repeat bZIP_1 PF00170.21 KEY64948.1 - 2.8e-11 43.3 8.2 2.8e-11 43.3 8.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KEY64948.1 - 6.8e-08 32.9 7.7 2e-07 31.4 7.7 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KEY64948.1 - 3.2e-05 23.9 6.3 3.2e-05 23.9 6.3 2.3 2 0 0 2 2 2 1 Basic region leucine zipper TMF_DNA_bd PF12329.8 KEY64948.1 - 7 6.7 12.7 0.93 9.5 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SUN PF03856.13 KEY64949.1 - 1.3e-92 309.7 9.8 1.6e-92 309.4 9.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MFS_1 PF07690.16 KEY64950.1 - 1.5e-15 57.0 17.9 3.1e-15 56.0 17.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF349 PF03993.12 KEY64950.1 - 0.01 16.1 0.3 0.023 15.0 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Hist_deacetyl PF00850.19 KEY64951.1 - 2.9e-80 270.0 0.0 4.1e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF1464 PF07318.12 KEY64951.1 - 0.22 10.6 0.0 0.46 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) ING PF12998.7 KEY64952.1 - 7.9e-22 77.8 4.5 1.3e-21 77.1 4.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KEY64952.1 - 7.2e-05 22.6 9.1 0.00014 21.7 9.1 1.5 1 0 0 1 1 1 1 PHD-finger DUF2552 PF10827.8 KEY64952.1 - 0.049 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) zf-HC5HC2H PF13771.6 KEY64952.1 - 0.08 13.2 0.8 0.16 12.2 0.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1704 PF08014.11 KEY64952.1 - 0.095 11.7 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) zf-RING_2 PF13639.6 KEY64952.1 - 0.22 11.9 6.8 0.43 11.0 6.8 1.5 1 0 0 1 1 1 0 Ring finger domain Methyltransf_16 PF10294.9 KEY64953.1 - 0.18 11.5 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Complex1_LYR_2 PF13233.6 KEY64954.1 - 1.5e-18 67.3 0.1 2e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KEY64954.1 - 4.4e-08 33.1 0.1 7.6e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HA2 PF04408.23 KEY64955.1 - 9.5e-18 64.5 0.0 9.5e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEY64955.1 - 6e-12 45.9 0.0 1.8e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KEY64955.1 - 2.4e-10 40.6 0.0 6.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KEY64955.1 - 2.6e-06 27.3 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY64955.1 - 0.00011 22.5 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEY64955.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY64955.1 - 0.036 14.4 0.2 0.19 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KEY64955.1 - 0.086 13.4 0.1 0.41 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KEY64957.1 - 7.7e-09 35.4 0.0 2e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RasGAP PF00616.19 KEY64957.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Rab5ip PF07019.12 KEY64958.1 - 1.9e-26 92.4 11.5 2.3e-26 92.2 11.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Transport_MerF PF11431.8 KEY64958.1 - 0.27 11.1 3.3 0.52 10.2 3.3 1.4 1 0 0 1 1 1 0 Membrane transport protein MerF URO-D PF01208.17 KEY64959.1 - 2.8e-128 427.9 0.0 3.2e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 KEY64960.1 - 1.3e-14 54.5 9.9 1.2e-11 45.0 3.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Velvet PF11754.8 KEY64961.1 - 5.8e-90 301.6 9.6 2.1e-89 299.8 0.0 2.4 2 0 0 2 2 2 1 Velvet factor TFIIA PF03153.13 KEY64961.1 - 1 9.3 11.4 2 8.3 11.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HisG PF01634.18 KEY64962.1 - 1.2e-50 171.7 0.0 1.6e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KEY64962.1 - 2.7e-28 97.9 0.1 5e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KEY64962.1 - 0.091 12.7 0.0 0.4 10.6 0.0 2.0 1 1 0 1 1 1 0 NMT1/THI5 like TraL PF07178.11 KEY64963.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 TraL protein IMUP PF15761.5 KEY64964.1 - 0.22 12.2 3.3 0.25 12.0 3.3 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KEY64964.1 - 1.1 8.8 8.6 1.3 8.6 8.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KEY64964.1 - 6.9 5.0 8.8 7.4 4.9 8.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ion_trans PF00520.31 KEY64965.1 - 4.8e-118 392.8 79.9 8.8e-43 146.3 2.2 4.7 4 1 0 4 4 4 4 Ion transport protein EF-hand_7 PF13499.6 KEY64965.1 - 0.081 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair PHD PF00628.29 KEY64966.1 - 2.2e-08 33.9 8.0 4.4e-08 32.9 8.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEY64966.1 - 0.018 14.6 4.6 0.033 13.7 4.6 1.4 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.19 KEY64967.1 - 8.2e-16 58.2 0.1 1.4e-14 54.2 0.1 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEY64967.1 - 1.5e-05 25.5 0.1 3.8e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KEY64967.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box MMgT PF10270.9 KEY64968.1 - 2.4e-35 120.9 0.0 2.8e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 KEY64969.1 - 1.1e-49 169.0 0.1 2.3e-49 168.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEY64969.1 - 4.2e-16 59.7 0.1 5.5e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain III AAA_30 PF13604.6 KEY64969.1 - 0.0054 16.5 0.1 0.75 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain CRAL_TRIO_N PF03765.15 KEY64969.1 - 0.13 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain MutS_IV PF05190.18 KEY64969.1 - 0.15 12.4 0.0 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 MutS family domain IV ABC_tran PF00005.27 KEY64969.1 - 0.16 12.5 0.1 32 5.0 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Adenylsucc_synt PF00709.21 KEY64972.1 - 1.1e-166 555.0 0.0 1.2e-166 554.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KRAB PF01352.27 KEY64973.1 - 0.04 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 KRAB box WD40 PF00400.32 KEY64974.1 - 6.6e-13 48.9 3.1 0.21 12.5 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY64974.1 - 0.026 14.8 0.1 4.8 7.5 0.0 3.4 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain UAA PF08449.11 KEY64975.1 - 2.3e-99 332.4 5.8 2.7e-99 332.2 5.8 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KEY64975.1 - 0.0022 17.2 5.1 0.0058 15.8 5.1 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KEY64975.1 - 0.0029 17.8 30.7 0.013 15.7 9.5 3.7 2 2 1 3 3 3 2 EamA-like transporter family DUF2613 PF11021.8 KEY64975.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) TMEM234 PF10639.9 KEY64975.1 - 0.14 12.2 4.9 0.4 10.7 1.0 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 A_deaminase PF00962.22 KEY64976.1 - 4.4e-123 410.8 0.1 6.3e-123 410.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_1 PF00018.28 KEY64977.1 - 7.4e-35 118.3 6.7 2.5e-13 49.4 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KEY64977.1 - 3e-34 116.6 0.0 5.2e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KEY64977.1 - 9.6e-34 115.0 9.3 2.9e-12 46.2 0.4 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KEY64977.1 - 1.3e-26 92.0 0.1 1.5e-07 31.0 0.0 5.2 5 0 0 5 5 5 4 Variant SH3 domain SAM_4 PF18017.1 KEY64977.1 - 0.00014 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 KEY64977.1 - 0.00024 21.3 6.2 0.0053 17.0 1.0 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_10 PF17902.1 KEY64977.1 - 0.00028 20.9 0.1 0.04 14.0 0.0 3.3 4 0 0 4 4 4 1 SH3 domain DUF1720 PF08226.11 KEY64977.1 - 0.00045 20.6 19.2 0.00045 20.6 19.2 6.9 2 1 4 6 6 6 2 Domain of unknown function (DUF1720) TRAM_LAG1_CLN8 PF03798.16 KEY64978.1 - 4e-50 170.3 14.6 5.7e-50 169.8 14.6 1.2 1 0 0 1 1 1 1 TLC domain Dor1 PF04124.12 KEY64979.1 - 1.4e-48 165.4 0.3 2.1e-41 141.7 0.2 2.7 1 1 1 2 2 2 2 Dor1-like family Prefoldin_2 PF01920.20 KEY64981.1 - 2.1e-15 56.5 4.6 2.8e-15 56.1 4.6 1.3 1 0 0 1 1 1 1 Prefoldin subunit Rab_bind PF16704.5 KEY64981.1 - 0.031 14.3 2.5 0.18 11.8 0.2 2.4 2 1 1 3 3 3 0 Rab binding domain DUF16 PF01519.16 KEY64981.1 - 1.3 9.6 6.1 1 9.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Thiolase_N PF00108.23 KEY64982.1 - 2.9e-16 59.6 0.0 8.5e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY64982.1 - 1.7e-12 47.1 0.3 5.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KEY64982.1 - 1.5e-06 27.9 0.1 6.1e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KEY64982.1 - 0.00097 19.1 0.1 0.038 14.0 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KEY64982.1 - 0.002 17.8 0.2 0.01 15.5 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KEY64982.1 - 0.0041 15.9 0.1 0.047 12.4 0.1 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) HMA PF00403.26 KEY64983.1 - 1.2e-14 54.5 0.4 1.6e-14 54.0 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Actin PF00022.19 KEY64984.1 - 8.9e-86 288.0 0.0 3.1e-52 177.6 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KEY64984.1 - 0.047 12.5 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KEY64985.1 - 1.2e-42 146.0 5.3 5.8e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 KEY64986.1 - 2.9e-95 318.9 0.0 3.3e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 CYYR1 PF10873.8 KEY64986.1 - 0.0078 16.7 0.3 0.94 9.9 0.0 2.3 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Rogdi_lz PF10259.9 KEY64986.1 - 0.028 13.9 0.6 0.028 13.9 0.6 1.7 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Sec39 PF08314.11 KEY64986.1 - 0.15 10.5 0.0 0.3 9.5 0.0 1.4 1 0 0 1 1 1 0 Secretory pathway protein Sec39 zf-C2HC5 PF06221.13 KEY64986.1 - 1.4 9.0 5.9 3.1 7.9 5.9 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type UNC45-central PF11701.8 KEY64987.1 - 1.3e-51 174.6 0.0 1.5e-50 171.2 0.0 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KEY64987.1 - 7.4 7.2 9.5 24 5.6 0.2 4.7 4 0 0 4 4 4 0 HEAT-like repeat tRNA_U5-meth_tr PF05958.11 KEY64988.1 - 4.3e-14 52.3 0.0 6.1e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KEY64988.1 - 6.7e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KEY64988.1 - 5.3e-06 26.3 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY64988.1 - 1.1e-05 26.0 0.0 4.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY64988.1 - 0.0059 17.2 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KEY64988.1 - 0.0078 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KEY64988.1 - 0.035 13.7 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY64988.1 - 0.15 12.8 0.0 0.36 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KEY64988.1 - 0.23 10.8 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) G_glu_transpept PF01019.21 KEY64989.1 - 2.5e-15 56.3 0.0 2.3e-13 49.8 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase ALG11_N PF15924.5 KEY64990.1 - 4.8e-83 278.3 0.0 8.6e-83 277.5 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KEY64990.1 - 2.9e-21 75.7 0.0 4.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY64990.1 - 2.5e-12 47.4 0.0 5.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 60KD_IMP PF02096.20 KEY64991.1 - 6e-07 29.5 0.0 8.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3325 PF11804.8 KEY64991.1 - 0.18 12.0 5.4 0.23 11.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Syntaxin_2 PF14523.6 KEY64992.1 - 1.1e-23 83.5 3.2 1.1e-23 83.5 3.2 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KEY64992.1 - 4.4e-12 45.8 1.3 1.3e-11 44.3 1.3 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KEY64992.1 - 0.00024 20.8 9.1 0.00024 20.8 9.1 1.8 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 KEY64992.1 - 0.0074 16.1 0.7 0.022 14.5 0.7 1.8 1 0 0 1 1 1 1 Synaptobrevin T2SSF PF00482.23 KEY64992.1 - 0.037 14.0 0.4 0.12 12.3 0.4 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Nre_C PF04895.12 KEY64992.1 - 0.24 11.3 1.7 0.37 10.7 0.2 2.0 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF1664 PF07889.12 KEY64992.1 - 0.43 10.6 8.1 4.3 7.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2650 PF10853.8 KEY64992.1 - 0.52 10.1 1.9 1 9.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) UPF0184 PF03670.13 KEY64992.1 - 0.52 10.7 0.1 0.52 10.7 0.1 2.8 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) DUF883 PF05957.13 KEY64992.1 - 0.62 10.7 9.6 0.93 10.1 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T3SSipB PF16535.5 KEY64992.1 - 0.82 10.1 16.2 0.052 14.0 9.8 2.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB UPF0242 PF06785.11 KEY64992.1 - 2.5 8.2 19.8 20 5.2 13.3 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KEY64992.1 - 3.7 8.2 7.0 16 6.2 1.2 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Ndc1_Nup PF09531.10 KEY64993.1 - 1.7e-188 628.2 0.9 2.4e-188 627.7 0.9 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup UPF0122 PF04297.14 KEY64993.1 - 0.015 15.5 0.2 0.46 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like NICE-3 PF07406.11 KEY64994.1 - 1.1e-05 25.6 0.9 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 2 NICE-3 protein DUF3810 PF12725.7 KEY64994.1 - 0.11 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Podoplanin PF05808.11 KEY64995.1 - 7.8 6.6 6.8 8.3 6.5 5.9 1.5 1 1 0 1 1 1 0 Podoplanin HSF_DNA-bind PF00447.17 KEY64996.1 - 2e-28 98.8 0.8 3.3e-28 98.1 0.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding GAT PF03127.14 KEY64996.1 - 0.076 13.3 0.1 4.9 7.5 0.2 2.3 2 0 0 2 2 2 0 GAT domain PGA_cap PF09587.10 KEY64996.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Hexapep PF00132.24 KEY64997.1 - 1.2e-12 47.0 19.5 2e-06 27.3 2.9 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEY64997.1 - 8.6e-12 44.6 18.6 5.5e-06 26.0 2.1 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KEY64997.1 - 7.4e-11 42.1 0.1 2e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KEY64997.1 - 0.0024 17.9 6.1 0.0052 16.9 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.6 KEY64997.1 - 0.087 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PPR_2 PF13041.6 KEY64998.1 - 3.6e-11 43.1 0.0 0.00019 21.6 0.0 5.6 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KEY64998.1 - 1.4e-07 31.4 0.0 0.00026 21.0 0.0 3.9 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Ribosomal_S7 PF00177.21 KEY64998.1 - 0.025 14.2 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e PPR_1 PF12854.7 KEY64998.1 - 0.069 12.9 0.0 15 5.3 0.0 4.0 4 0 0 4 4 4 0 PPR repeat cwf18 PF08315.12 KEY64999.1 - 3.6e-47 160.4 6.9 3.6e-47 160.4 6.9 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 KEY65000.1 - 7.5e-10 38.6 0.7 2e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle ANAPC15 PF15243.6 KEY65000.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 15 SUZ PF12752.7 KEY65001.1 - 2.1e-14 54.0 1.2 2.1e-14 54.0 1.2 2.8 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 KEY65001.1 - 1.8e-07 31.0 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain MitMem_reg PF13012.6 KEY65002.1 - 2e-18 66.9 0.4 4.5e-18 65.7 0.2 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KEY65002.1 - 2e-17 63.2 0.0 3.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rubella_Capsid PF05750.11 KEY65002.1 - 0.12 11.9 2.8 0.18 11.4 2.8 1.2 1 0 0 1 1 1 0 Rubella capsid protein UTP25 PF06862.12 KEY65003.1 - 1.1e-196 654.2 0.0 1.3e-196 654.0 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KEY65003.1 - 0.0043 16.8 0.0 0.1 12.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L17 PF01196.19 KEY65004.1 - 6e-30 104.0 2.4 8.6e-30 103.5 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 KEY65004.1 - 0.027 14.7 0.5 0.076 13.3 0.0 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 KEY65005.1 - 1e-18 67.9 4.9 1e-18 67.9 4.9 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF883 PF05957.13 KEY65005.1 - 0.04 14.5 14.4 2.2 8.9 2.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4131 PF13567.6 KEY65005.1 - 0.048 13.3 0.5 0.67 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Apolipoprotein PF01442.18 KEY65005.1 - 0.086 12.7 13.5 0.22 11.4 13.3 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ALAD PF00490.21 KEY65007.1 - 2.9e-121 404.5 0.0 3.4e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.22 KEY65008.1 - 7.4e-44 150.2 30.5 1.1e-43 149.7 30.5 1.2 1 0 0 1 1 1 1 Acyltransferase family CitMHS PF03600.16 KEY65008.1 - 0.071 12.3 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Citrate transporter Amidohydro_3 PF07969.11 KEY65009.1 - 1.2e-67 229.4 1.5 1.5e-67 229.1 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KEY65009.1 - 2.4e-08 33.7 0.0 7.5e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family DUF3040 PF11239.8 KEY65012.1 - 0.083 13.2 0.8 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AP3D1 PF06375.11 KEY65013.1 - 0.048 13.9 13.6 0.042 14.1 13.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SR-25 PF10500.9 KEY65013.1 - 0.068 12.8 18.2 0.059 13.0 18.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.13 KEY65013.1 - 0.17 12.5 2.7 0.18 12.4 2.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 KEY65013.1 - 0.57 10.2 11.1 0.5 10.4 11.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1279 PF06916.13 KEY65014.1 - 1e-23 83.7 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PNGaseA PF12222.8 KEY65016.1 - 3.4e-116 388.7 0.0 4.5e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Inhibitor_I53 PF11714.8 KEY65017.1 - 0.15 12.3 0.5 0.22 11.8 0.5 1.2 1 0 0 1 1 1 0 Thrombin inhibitor Madanin MARVEL PF01284.23 KEY65018.1 - 1.3e-24 86.8 14.1 1.6e-24 86.6 14.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3974 PF13120.6 KEY65019.1 - 0.13 12.4 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) eIF-5_eIF-2B PF01873.17 KEY65020.1 - 9.2e-42 141.6 0.7 1.6e-41 140.9 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 T6SS_VasJ PF16989.5 KEY65020.1 - 0.098 12.1 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TF_Zn_Ribbon PF08271.12 KEY65020.1 - 0.13 11.8 0.7 0.27 10.8 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.12 KEY65020.1 - 0.72 9.7 3.8 5.1 7.0 4.1 2.3 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KEY65020.1 - 1.2 9.5 8.0 1.4 9.3 0.4 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Nucleoporin_C PF03177.14 KEY65021.1 - 1.1e-154 516.5 17.6 1.3e-154 516.2 17.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KEY65021.1 - 5e-75 252.9 0.0 7.2e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like AFG1_ATPase PF03969.16 KEY65022.1 - 1.7e-51 175.2 0.0 6e-26 91.2 0.0 5.0 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 KEY65022.1 - 4.2e-05 24.0 0.5 0.011 16.1 0.0 3.4 3 1 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 KEY65022.1 - 8.4e-05 22.6 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY65022.1 - 0.0033 17.7 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KEY65022.1 - 0.013 15.3 0.0 4.8 7.0 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA PF00004.29 KEY65022.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEY65022.1 - 0.038 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KEY65022.1 - 0.08 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Acyl_transf_1 PF00698.21 KEY65023.1 - 4.2e-19 69.2 0.0 5.6e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.13 KEY65023.1 - 2.7e-06 27.6 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Adap_comp_sub PF00928.21 KEY65024.1 - 6.9e-70 235.4 0.0 8.5e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEY65024.1 - 4.4e-05 23.4 0.0 7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.6 KEY65025.1 - 0.0031 17.7 4.9 0.0089 16.2 4.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) ECR1_N PF14382.6 KEY65026.1 - 9.4e-12 44.5 0.8 1.7e-11 43.7 0.2 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KEY65026.1 - 2.6e-05 24.5 0.1 6e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KEY65026.1 - 0.018 15.7 0.4 0.44 11.2 0.1 2.5 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 Aldedh PF00171.22 KEY65027.1 - 4.2e-75 253.0 0.0 5.1e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3197 PF11432.8 KEY65027.1 - 0.035 14.0 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) DUF5495 PF17599.2 KEY65027.1 - 0.16 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5495) MRP-S28 PF10213.9 KEY65028.1 - 1.6e-46 157.8 0.1 4.3e-45 153.2 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 KEY65029.1 - 4.3e-20 72.3 0.0 2.1e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KEY65029.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase WD40 PF00400.32 KEY65030.1 - 9.3e-34 114.9 23.1 5.9e-05 23.8 0.0 11.1 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65030.1 - 4.5e-16 58.9 6.0 9.7e-05 22.6 0.2 6.0 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KEY65030.1 - 0.00028 20.7 4.2 0.81 9.7 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEY65030.1 - 0.00099 18.2 2.6 1.7 7.6 0.1 4.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEY65030.1 - 0.075 12.9 0.3 2.4 8.0 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEY65030.1 - 0.19 11.0 0.0 2.7 7.3 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 KEY65030.1 - 1.7 9.2 13.4 0.94 10.1 0.1 5.9 5 1 0 5 5 5 0 PQQ-like domain CFEM PF05730.11 KEY65031.1 - 1.3 9.2 12.4 3.3 7.9 12.2 1.9 1 1 0 1 1 1 0 CFEM domain MGC-24 PF05283.11 KEY65031.1 - 5.7 7.4 16.8 12 6.4 16.8 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1206 PF06724.11 KEY65031.1 - 8.2 6.6 9.3 1.8 8.7 5.5 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) p450 PF00067.22 KEY65034.1 - 3.7e-68 230.3 0.0 4.5e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alba PF01918.21 KEY65035.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Alba BNIP2 PF12496.8 KEY65035.1 - 0.032 14.7 0.2 0.039 14.4 0.2 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF202 PF02656.15 KEY65036.1 - 5.1e-15 55.7 5.0 5.1e-15 55.7 5.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.13 KEY65037.1 - 9.6e-24 83.6 0.0 1.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Pex14_N PF04695.13 KEY65038.1 - 0.063 13.9 5.5 0.099 13.3 5.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fringe PF02434.16 KEY65039.1 - 0.026 14.0 0.8 0.35 10.3 0.8 2.1 1 1 0 1 1 1 0 Fringe-like DUF604 PF04646.12 KEY65039.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Ceramidase_alk PF04734.13 KEY65040.1 - 5.9e-219 727.9 0.0 6.9e-219 727.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KEY65040.1 - 3.4e-58 196.2 0.1 5.6e-58 195.5 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal bZIP_1 PF00170.21 KEY65041.1 - 6.1 7.0 13.1 2.1 8.5 9.0 2.0 1 1 1 2 2 2 0 bZIP transcription factor Metallophos PF00149.28 KEY65043.1 - 2.2e-31 110.0 0.3 3.3e-22 80.0 0.1 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEY65043.1 - 0.035 14.5 0.1 0.089 13.2 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KEY65044.1 - 0.00025 21.0 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 GRP PF07172.11 KEY65045.1 - 0.4 11.4 14.3 1.1 10.0 14.3 1.7 1 0 0 1 1 1 0 Glycine rich protein family DUF1179 PF06678.11 KEY65045.1 - 4.5 7.3 6.2 0.32 11.0 0.9 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1179) DUF5610 PF18433.1 KEY65046.1 - 0.068 13.7 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) Cyclin_N PF00134.23 KEY65047.1 - 1.9e-06 27.6 0.0 1.6e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain CPSase_L_D2 PF02786.17 KEY65048.1 - 4.1e-113 376.1 0.2 4.9e-84 281.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KEY65048.1 - 4.4e-48 163.6 0.0 1.1e-47 162.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KEY65048.1 - 7.3e-47 158.4 0.0 1.6e-46 157.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KEY65048.1 - 6.9e-46 155.9 0.0 1.5e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KEY65048.1 - 9.5e-40 135.7 0.0 2.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KEY65048.1 - 1.1e-29 103.5 0.0 2.9e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KEY65048.1 - 2.9e-23 81.9 0.0 1.4e-22 79.7 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KEY65048.1 - 2.3e-17 63.2 0.6 9e-08 31.9 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEY65048.1 - 5.4e-15 55.4 0.1 8.9e-07 28.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KEY65048.1 - 4e-11 42.8 0.0 5.1e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KEY65048.1 - 4e-06 26.7 0.1 0.00041 20.2 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KEY65048.1 - 8e-06 26.0 0.4 0.036 14.1 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KEY65048.1 - 2.8e-05 24.0 0.1 0.013 15.3 0.0 3.8 3 0 0 3 3 3 1 DJ-1/PfpI family RimK PF08443.11 KEY65048.1 - 0.0015 18.2 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 KEY65048.1 - 0.002 17.9 0.2 4.4 7.0 0.0 3.3 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PC-Esterase PF13839.6 KEY65048.1 - 0.096 12.4 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PNP_phzG_C PF10590.9 KEY65049.1 - 3.8e-19 68.5 2.8 8.4e-19 67.4 2.8 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KEY65049.1 - 3.6e-16 59.1 0.0 6.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.21 KEY65050.1 - 3.4e-62 210.7 0.0 4.1e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY65050.1 - 0.18 10.3 0.0 0.5 8.8 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 KEY65050.1 - 0.21 10.4 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Allinase Glyco_hydro_76 PF03663.14 KEY65051.1 - 2.1e-133 445.4 2.9 2.4e-133 445.2 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY65051.1 - 0.0045 16.1 3.9 2.4 7.2 0.3 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KEY65051.1 - 0.13 10.7 0.5 0.69 8.3 0.0 2.1 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Ald_Xan_dh_C PF01315.22 KEY65053.1 - 0.039 14.3 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MGC-24 PF05283.11 KEY65053.1 - 6.6 7.2 11.5 7.5 7.0 10.1 1.7 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MscL PF01741.18 KEY65054.1 - 1.4e-18 67.3 0.1 1.7e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 KEY65054.1 - 0.022 14.6 1.0 0.036 14.0 1.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KEY65054.1 - 0.034 14.2 0.8 0.053 13.5 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon Cullin PF00888.22 KEY65056.1 - 4.7e-196 653.1 1.8 5.9e-196 652.8 1.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEY65056.1 - 4.4e-26 90.7 3.8 1.8e-25 88.7 3.8 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KEY65056.1 - 0.0021 18.5 0.6 0.013 16.0 0.6 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal TrmE_N PF10396.9 KEY65056.1 - 0.13 12.6 0.1 2.1 8.7 0.0 3.0 4 0 0 4 4 4 0 GTP-binding protein TrmE N-terminus DUF1803 PF08820.10 KEY65056.1 - 0.26 11.3 4.8 12 6.0 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1803) DUF1706 PF08020.11 KEY65056.1 - 0.36 10.7 4.1 21 5.0 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1706) PRD PF00874.20 KEY65056.1 - 2.5 8.4 8.7 11 6.4 0.6 3.7 3 0 0 3 3 3 0 PRD domain Avl9 PF09794.9 KEY65057.1 - 4.6e-142 473.2 0.0 6e-142 472.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KEY65057.1 - 3.9e-06 26.8 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.9 KEY65057.1 - 8.3e-06 25.6 0.8 0.00069 19.3 0.1 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) MCLC PF05934.11 KEY65057.1 - 2.8 6.6 4.4 1.9 7.1 1.6 1.9 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) G-alpha PF00503.20 KEY65058.1 - 1.8e-115 385.9 0.5 2e-115 385.7 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEY65058.1 - 1.3e-15 57.3 0.6 5e-10 39.1 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEY65058.1 - 0.0008 18.8 2.9 0.097 12.0 0.2 2.4 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KEY65058.1 - 0.0035 17.6 0.4 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KEY65058.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KEY65059.1 - 0 1057.8 0.1 0 1057.6 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 KEY65060.1 - 1.1e-68 231.5 0.0 1.4e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65060.1 - 2.8e-32 112.0 0.0 3.9e-32 111.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY65060.1 - 7.2e-06 25.2 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY65060.1 - 5.7e-05 22.6 0.1 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY65060.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY65060.1 - 0.0008 18.8 0.0 0.067 12.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KEY65060.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KEY65060.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ABC_tran PF00005.27 KEY65061.1 - 2.3e-52 177.1 0.0 3.1e-29 102.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY65061.1 - 3.5e-33 115.4 27.2 1e-18 68.0 11.4 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY65061.1 - 4.6e-10 39.3 1.3 0.009 15.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEY65061.1 - 3.2e-07 31.0 0.5 0.00015 22.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEY65061.1 - 3.4e-07 30.0 0.1 0.006 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEY65061.1 - 7.5e-07 28.8 1.7 0.041 13.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY65061.1 - 3.4e-05 23.8 0.2 0.13 12.0 0.1 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KEY65061.1 - 3.7e-05 23.1 0.2 0.8 8.8 0.0 3.8 2 2 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 KEY65061.1 - 5.5e-05 23.1 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEY65061.1 - 6e-05 23.5 0.1 0.73 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY65061.1 - 9.1e-05 22.8 0.5 0.62 10.3 0.1 3.2 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 KEY65061.1 - 0.00045 19.4 0.1 0.15 11.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KEY65061.1 - 0.00063 19.8 0.1 0.13 12.3 0.1 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KEY65061.1 - 0.00083 19.5 4.4 0.0044 17.2 0.4 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KEY65061.1 - 0.0027 17.9 0.1 1.2 9.5 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KEY65061.1 - 0.0029 17.2 1.2 0.65 9.6 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KEY65061.1 - 0.0058 16.7 0.1 1.3 9.0 0.2 2.7 3 0 0 3 3 2 1 Dynamin family AAA_33 PF13671.6 KEY65061.1 - 0.0065 16.6 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KEY65061.1 - 0.0069 15.9 2.6 0.86 9.0 0.2 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_10 PF12846.7 KEY65061.1 - 0.013 14.4 0.0 0.032 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.12 KEY65061.1 - 0.018 14.9 3.7 2.4 8.0 0.1 2.9 3 0 0 3 3 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KEY65061.1 - 0.019 14.3 0.4 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KEY65061.1 - 0.022 14.5 0.5 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KEY65061.1 - 0.024 14.4 0.0 6.8 6.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KEY65061.1 - 0.03 14.9 0.1 9.5 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 KEY65061.1 - 0.039 13.2 0.0 7.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 KEY65061.1 - 0.041 13.7 1.3 4.1 7.1 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KEY65061.1 - 0.043 13.7 0.7 12 5.8 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KEY65061.1 - 0.044 13.8 0.0 4.5 7.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KEY65061.1 - 0.08 13.2 0.1 25 5.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 KEY65061.1 - 0.1 12.3 0.0 14 5.4 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KEY65061.1 - 0.11 12.0 0.2 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KEY65061.1 - 0.17 11.8 0.8 7.9 6.4 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KEY65061.1 - 0.32 11.0 1.2 16 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEY65061.1 - 0.34 11.3 1.1 47 4.4 0.1 3.3 3 1 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 KEY65061.1 - 0.55 9.1 2.4 29 3.4 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KEY65061.1 - 5.6 6.6 8.9 3.9 7.1 0.0 3.6 5 0 0 5 5 3 0 AAA domain DUF1774 PF08611.10 KEY65062.1 - 2.2e-39 133.7 4.8 2.2e-39 133.7 4.8 2.9 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Ank_5 PF13857.6 KEY65063.1 - 1.2e-32 111.5 6.3 2.8e-07 30.7 0.0 9.1 6 2 4 10 10 10 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY65063.1 - 1.8e-32 111.7 4.1 2.1e-08 34.6 0.1 7.7 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY65063.1 - 4e-31 107.0 1.1 3.1e-09 37.2 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY65063.1 - 1.3e-22 77.4 5.6 0.00069 19.9 0.0 11.4 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 KEY65063.1 - 4.5e-22 77.4 9.1 0.019 15.4 0.0 10.0 10 1 1 11 11 11 5 Ankyrin repeat LysM PF01476.20 KEY65064.1 - 1.6e-15 56.8 0.0 0.00024 21.1 0.0 4.4 4 0 0 4 4 4 4 LysM domain LysM PF01476.20 KEY65065.1 - 7.8e-13 48.3 0.0 4.1e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 LysM domain Phage_tail_X PF05489.12 KEY65065.1 - 0.033 13.8 0.2 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Phage Tail Protein X Glyco_hydro_18 PF00704.28 KEY65066.1 - 3.4e-58 197.8 0.0 4.7e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY65066.1 - 1.4e-10 41.5 38.3 8e-09 35.8 7.5 3.8 4 0 0 4 4 4 2 Chitin recognition protein Ank_4 PF13637.6 KEY65067.1 - 7.7e-36 122.0 9.3 6.4e-09 36.2 0.0 9.5 8 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY65067.1 - 3e-31 107.8 2.1 2.2e-05 24.9 0.0 6.7 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY65067.1 - 1.3e-26 92.3 8.7 7.5e-06 26.1 0.1 8.2 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KEY65067.1 - 3.4e-20 71.5 15.3 0.015 15.7 0.2 11.2 12 0 0 12 12 12 4 Ankyrin repeat Ank_3 PF13606.6 KEY65067.1 - 7.1e-20 69.0 3.1 0.00074 19.8 0.0 11.5 11 2 0 11 11 11 4 Ankyrin repeat zinc_ribbon_15 PF17032.5 KEY65069.1 - 3.7e-05 24.4 0.9 5.4e-05 23.9 0.9 1.2 1 0 0 1 1 1 1 zinc-ribbon family Glyco_transf_28 PF03033.20 KEY65070.1 - 3.7e-18 65.9 0.5 9.3e-10 38.7 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KEY65070.1 - 2.3e-05 24.7 0.0 7.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KEY65070.1 - 0.0001 21.3 0.1 0.00016 20.6 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEY65070.1 - 0.0029 17.6 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Sec61_beta PF03911.16 KEY65071.1 - 3.8e-19 68.4 1.9 5.1e-19 68.0 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family Aconitase PF00330.20 KEY65072.1 - 3.4e-89 300.0 0.8 2.1e-81 274.2 0.3 3.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEY65072.1 - 7.5e-21 74.8 0.0 1.5e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NIF PF03031.18 KEY65073.1 - 1.5e-54 184.0 0.4 2.1e-54 183.5 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4604 PF15377.6 KEY65073.1 - 2.6 8.4 17.3 0.027 14.9 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) ABC_membrane_2 PF06472.15 KEY65074.1 - 1.5e-91 306.5 2.5 2.3e-91 305.9 0.3 2.2 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEY65074.1 - 1.8e-16 60.9 0.1 4.4e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KEY65074.1 - 0.007 16.9 1.5 0.95 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEY65074.1 - 0.0077 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEY65074.1 - 0.017 15.5 1.1 0.032 14.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KEY65074.1 - 0.041 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KEY65074.1 - 0.14 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KEY65074.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KEY65074.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEY65074.1 - 0.21 11.1 0.0 0.51 9.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HC2 PF07382.11 KEY65076.1 - 3.4 7.7 26.0 12 5.9 26.0 1.9 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Aldo_ket_red PF00248.21 KEY65077.1 - 2.1e-43 148.6 0.0 2.7e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KEY65078.1 - 4.2e-34 116.0 27.4 6.1e-08 32.8 1.4 6.8 1 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY65078.1 - 1.9e-23 82.0 24.6 1.7e-05 24.4 0.4 6.7 4 2 3 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 KEY65078.1 - 2.8e-15 56.3 10.2 4.1e-07 29.7 1.7 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KEY65078.1 - 9.4e-06 25.3 23.8 0.11 12.6 1.0 8.1 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 KEY65078.1 - 0.0012 19.1 27.3 7.5 7.5 0.1 8.5 8 1 0 8 8 8 2 Leucine Rich Repeat Abhydrolase_1 PF00561.20 KEY65079.1 - 3.6e-06 26.8 0.0 9.3e-05 22.2 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY65079.1 - 6e-05 23.8 2.7 6e-05 23.8 2.7 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY65079.1 - 0.0001 21.6 0.0 0.022 14.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEY65079.1 - 0.00047 20.1 0.1 0.00096 19.1 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY65079.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family BTB PF00651.31 KEY65080.1 - 9.4e-08 32.3 0.1 4.1e-07 30.2 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.27 KEY65081.1 - 5.6e-12 46.1 0.0 1.3e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.28 KEY65081.1 - 0.029 14.2 0.4 0.085 12.7 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 KEY65082.1 - 1.2e-53 180.3 0.1 1.7e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans PF04082.18 KEY65083.1 - 4.7e-15 55.3 0.0 8.2e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65083.1 - 2.4e-08 34.0 12.1 4.5e-08 33.1 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.7 KEY65084.1 - 9.3e-37 126.8 0.0 1.3e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3018 PF11455.8 KEY65084.1 - 0.037 13.9 0.1 0.081 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) AstA PF04958.12 KEY65084.1 - 0.23 10.0 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF1772 PF08592.11 KEY65085.1 - 9.3e-27 94.0 9.3 1.2e-26 93.7 9.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) 3-PAP PF12578.8 KEY65085.1 - 0.16 11.7 0.0 4.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Myotubularin-associated protein AT_hook PF02178.19 KEY65086.1 - 0.068 13.1 6.4 0.18 11.8 6.4 1.8 1 0 0 1 1 1 0 AT hook motif Ric8 PF10165.9 KEY65087.1 - 1.2e-132 443.3 0.1 1.3e-132 443.1 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KEY65088.1 - 4.1e-139 463.7 0.2 6e-139 463.2 0.2 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal AIF_C PF14721.6 KEY65088.1 - 6.6 7.1 6.7 11 6.4 4.9 2.3 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sugar_tr PF00083.24 KEY65089.1 - 7.1e-111 371.3 19.3 8.9e-111 370.9 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY65089.1 - 1.1e-22 80.4 33.0 1.2e-14 54.0 7.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEY65089.1 - 0.18 10.1 6.2 0.044 12.1 2.8 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aldose_epim PF01263.20 KEY65090.1 - 2.3e-40 138.8 0.0 2.8e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 KEY65091.1 - 2.2e-201 669.1 0.0 2.5e-201 668.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Secretin_N PF03958.17 KEY65092.1 - 0.14 12.6 3.9 0.23 11.9 3.9 1.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain SWIRM-assoc_2 PF16496.5 KEY65093.1 - 4e-06 26.0 0.3 4e-06 26.0 0.3 4.0 3 2 0 3 3 3 1 SWIRM-associated domain at the N-terminal Asp PF00026.23 KEY65094.1 - 3.2e-59 200.9 0.0 4.5e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY65094.1 - 4.4e-11 43.3 0.3 8e-09 36.0 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY65094.1 - 0.00074 20.1 0.0 11 6.8 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KEY65094.1 - 0.075 13.6 0.0 13 6.4 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease GTP_EFTU PF00009.27 KEY65095.1 - 1.2e-59 201.1 0.2 2.1e-59 200.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KEY65095.1 - 3.3e-31 107.2 0.0 7.3e-31 106.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KEY65095.1 - 9.4e-30 102.9 0.0 2.3e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KEY65095.1 - 8.2e-23 80.3 0.0 1.9e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY65095.1 - 2.1e-13 50.5 0.0 5.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KEY65095.1 - 1.3e-06 28.3 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 KEY65095.1 - 0.047 13.8 0.3 0.89 9.7 0.0 3.0 3 0 0 3 3 3 0 Putative phosphatase (DUF442) FAD_binding_3 PF01494.19 KEY65097.1 - 7.7e-18 64.8 0.0 1.5e-17 63.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY65097.1 - 1.7e-05 24.9 0.0 5.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY65097.1 - 6.2e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY65097.1 - 0.0023 17.6 0.0 0.0059 16.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY65097.1 - 0.0053 17.3 0.0 0.015 15.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY65097.1 - 0.0058 15.4 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KEY65097.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 KEY65097.1 - 0.032 13.3 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase XdhC_C PF13478.6 KEY65097.1 - 0.04 14.4 0.0 0.084 13.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.22 KEY65097.1 - 0.045 12.8 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M24 PF00557.24 KEY65098.1 - 8.9e-43 146.4 0.1 1.2e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KEY65098.1 - 2.8e-21 75.6 7.1 5.2e-21 74.7 7.1 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KEY65098.1 - 0.00043 20.3 4.3 0.00043 20.3 4.3 2.2 2 0 0 2 2 2 1 MYND finger Dynein_light PF01221.18 KEY65099.1 - 1.2e-39 134.5 1.5 1.4e-39 134.3 1.5 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 KEY65100.1 - 3e-72 238.4 0.1 2e-18 66.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY65100.1 - 1.5e-08 34.3 0.0 0.0076 16.1 0.0 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KEY65100.1 - 3.8e-05 23.7 0.0 2.9 8.0 0.0 5.6 5 0 0 5 5 5 1 Limkain b1 RRM_7 PF16367.5 KEY65100.1 - 7.8e-05 22.7 0.0 1.2 9.3 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KEY65100.1 - 0.00015 21.8 0.0 2.2 8.4 0.0 4.4 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 KEY65100.1 - 0.00026 20.9 0.0 0.79 9.8 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.15 KEY65100.1 - 0.00089 19.3 1.6 0.28 11.2 0.8 3.8 3 2 0 3 3 3 1 Smg-4/UPF3 family TEA PF01285.18 KEY65101.1 - 1.4e-26 92.3 0.0 2.8e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain DUF3504 PF12012.8 KEY65101.1 - 0.44 10.4 2.4 1.1 9.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) AHSA1 PF08327.11 KEY65103.1 - 0.11 12.7 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Pro_isomerase PF00160.21 KEY65104.1 - 1.1e-48 165.5 0.1 1.3e-48 165.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KEY65104.1 - 0.048 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain zf-RING_2 PF13639.6 KEY65105.1 - 6.2e-12 45.7 6.0 9.5e-12 45.1 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEY65105.1 - 3.8e-08 32.9 0.6 6.3e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY65105.1 - 3.9e-08 33.0 5.7 6e-08 32.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY65105.1 - 5.8e-08 32.5 3.2 9.3e-08 31.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEY65105.1 - 5e-06 26.7 9.4 2.4e-05 24.5 9.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEY65105.1 - 5.7e-06 26.2 3.4 9e-06 25.6 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY65105.1 - 0.00097 19.1 0.8 0.00097 19.1 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY65105.1 - 0.0016 18.3 2.2 0.0026 17.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEY65105.1 - 0.0025 17.8 3.2 0.0061 16.6 3.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KEY65105.1 - 0.053 13.3 6.3 0.091 12.6 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KEY65105.1 - 0.15 11.9 4.5 0.29 11.0 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KEY65105.1 - 0.18 11.7 5.6 0.31 11.0 5.6 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KEY65105.1 - 0.24 11.0 4.1 0.41 10.3 4.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KEY65105.1 - 0.33 11.2 4.0 0.7 10.1 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KEY65105.1 - 0.5 10.6 2.5 1.4 9.2 2.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain OAD_gamma PF04277.13 KEY65105.1 - 1 10.0 0.0 1 10.0 0.0 3.5 3 2 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zf-C3H2C3 PF17122.5 KEY65105.1 - 3.2 7.8 5.3 6.3 6.9 5.3 1.5 1 0 0 1 1 1 0 Zinc-finger DUF3752 PF12572.8 KEY65106.1 - 4.5e-52 176.6 12.5 4.5e-52 176.6 12.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Vps8 PF12816.7 KEY65107.1 - 1.1e-73 246.9 0.1 3.7e-73 245.3 0.0 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.12 KEY65107.1 - 1.6e-50 170.0 0.6 3.9e-50 168.8 0.6 1.7 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.20 KEY65107.1 - 6.6e-08 32.5 0.0 6.1e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF4160 PF13711.6 KEY65107.1 - 0.0019 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) DPM2 PF07297.12 KEY65107.1 - 0.081 13.2 7.8 0.19 12.0 7.8 1.5 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Helicase_C PF00271.31 KEY65108.1 - 5e-24 84.8 0.0 1.8e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY65108.1 - 1.4e-22 80.3 0.0 5e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEY65108.1 - 0.00068 19.7 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA_synt_1c_R2 PF04557.15 KEY65108.1 - 0.002 19.0 1.5 0.002 19.0 1.5 2.3 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA-synt_2 PF00152.20 KEY65109.1 - 1.6e-61 208.1 0.0 1.8e-49 168.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEY65109.1 - 9.9e-12 44.7 0.0 5e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEY65109.1 - 1.9e-05 24.3 0.0 0.0083 15.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_OB PF17207.3 KEY65109.1 - 0.77 9.6 2.4 18 5.2 0.4 2.6 3 0 0 3 3 3 0 MCM OB domain Actin PF00022.19 KEY65110.1 - 3.2e-148 493.7 0.0 3.7e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEY65110.1 - 9.5e-07 27.9 0.2 0.0042 15.9 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein MutL PF13941.6 KEY65110.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 MutL protein UDG PF03167.19 KEY65111.1 - 1.9e-20 73.4 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 KEY65112.1 - 1.5e-55 188.5 0.0 2e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KEY65112.1 - 0.036 14.4 0.1 0.099 13.0 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pyr_redox_2 PF07992.14 KEY65113.1 - 1.8e-47 162.0 0.5 2.2e-47 161.7 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY65113.1 - 9.4e-18 64.6 0.1 5.8e-16 58.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY65113.1 - 4.9e-17 62.1 0.3 9.4e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY65113.1 - 0.0004 20.6 0.2 0.062 13.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KEY65113.1 - 0.0018 18.7 0.1 0.037 14.4 0.1 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KEY65113.1 - 0.0028 16.8 0.1 0.18 10.9 0.0 2.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KEY65113.1 - 0.0039 16.8 1.2 0.69 9.4 0.0 3.2 2 2 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEY65113.1 - 0.004 16.5 0.3 0.45 9.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEY65113.1 - 0.0042 16.2 2.1 2.8 6.9 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.17 KEY65113.1 - 0.0091 15.3 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KEY65113.1 - 0.04 13.0 4.3 1 8.3 1.8 2.9 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KEY65113.1 - 0.099 12.6 0.5 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding HMW1C_N PF18071.1 KEY65113.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 HMW1C N-terminal Vps53_N PF04100.12 KEY65114.1 - 1.5e-104 350.0 0.4 2.5e-104 349.3 0.4 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KEY65114.1 - 4e-10 39.5 3.5 7.1e-10 38.6 3.5 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 KEY65114.1 - 3.3e-05 23.0 0.7 0.14 11.0 0.0 3.0 3 0 0 3 3 3 2 RINT-1 / TIP-1 family DUF2451 PF10474.9 KEY65114.1 - 0.00016 21.5 0.0 0.00065 19.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 KEY65114.1 - 0.0017 17.3 2.9 0.0029 16.5 2.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein XhlA PF10779.9 KEY65114.1 - 0.0065 16.7 1.4 0.062 13.5 0.5 2.8 2 0 0 2 2 2 1 Haemolysin XhlA Zw10 PF06248.13 KEY65114.1 - 0.0081 14.8 3.4 0.016 13.8 3.4 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF892 PF05974.12 KEY65114.1 - 0.012 15.6 3.7 0.012 15.6 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Baculo_PEP_C PF04513.12 KEY65114.1 - 0.021 14.8 3.5 0.053 13.6 3.0 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 KEY65114.1 - 0.022 14.1 2.2 0.048 13.0 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KEY65114.1 - 0.028 14.5 1.4 0.07 13.2 0.6 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) VPS53_C PF16854.5 KEY65114.1 - 0.028 14.3 0.0 0.19 11.6 0.0 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus HTH_30 PF13556.6 KEY65114.1 - 0.062 13.1 0.2 0.22 11.3 0.2 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF3919 PF13057.6 KEY65114.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) COG2 PF06148.11 KEY65114.1 - 0.48 10.5 5.3 1.7 8.7 2.8 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 KEY65114.1 - 2.1 7.8 5.9 4.7 6.7 5.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit MitMem_reg PF13012.6 KEY65114.1 - 4 7.9 6.0 16 6.0 2.6 3.3 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function fn3 PF00041.21 KEY65115.1 - 1.5e-05 25.2 0.1 6.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain IF-2B PF01008.17 KEY65115.1 - 0.33 10.1 3.2 0.61 9.3 3.2 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family Spc7 PF08317.11 KEY65115.1 - 0.57 9.0 42.4 0.014 14.3 27.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KEY65115.1 - 9.1 6.7 17.2 0.45 10.8 8.4 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LNS2 PF08235.13 KEY65116.1 - 2.2e-94 315.2 0.0 2.9e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KEY65116.1 - 4.1e-42 142.3 0.0 1.7e-41 140.3 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KEY65116.1 - 2.8e-05 23.8 0.0 0.02 14.5 0.0 2.8 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) Histidinol_dh PF00815.20 KEY65117.1 - 5.7e-161 536.1 5.1 8.5e-161 535.5 5.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KEY65117.1 - 4.1e-22 77.8 0.0 8e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KEY65117.1 - 2.4e-14 53.5 0.6 1.4e-13 51.1 0.3 2.5 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.15 KEY65118.1 - 7.2e-42 142.3 0.0 9.6e-42 141.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_M16 PF00675.20 KEY65119.1 - 9.9e-58 194.3 0.4 2.1e-57 193.3 0.4 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEY65119.1 - 5.8e-40 137.3 0.0 3.8e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.13 KEY65119.1 - 0.082 13.3 0.2 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 RbsD / FucU transport protein family Raffinose_syn PF05691.12 KEY65120.1 - 7.5e-57 192.7 0.8 1e-43 149.2 0.2 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KEY65120.1 - 0.021 13.8 0.6 0.033 13.2 0.6 1.2 1 0 0 1 1 1 0 Melibiase ocr PF08684.10 KEY65120.1 - 0.021 15.2 0.1 0.057 13.9 0.1 1.7 1 0 0 1 1 1 0 DNA mimic ocr IMPDH PF00478.25 KEY65121.1 - 4.2e-127 423.9 2.4 5e-127 423.7 2.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KEY65121.1 - 1.1e-13 51.4 0.1 1.4e-06 28.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KEY65121.1 - 6.1e-08 32.1 1.8 1.6e-06 27.4 0.5 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KEY65121.1 - 1.2e-07 31.5 2.9 0.0094 15.4 2.9 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KEY65121.1 - 0.00052 19.5 2.2 0.012 15.1 0.2 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KEY65121.1 - 0.024 13.9 0.8 0.1 11.9 0.4 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PK PF00224.21 KEY65121.1 - 0.064 12.1 0.0 0.15 10.9 0.0 1.5 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Acetyltransf_1 PF00583.25 KEY65122.1 - 6.4e-10 39.3 0.0 9.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY65122.1 - 1.4e-05 25.1 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY65122.1 - 0.00051 20.4 0.0 0.00081 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY65122.1 - 0.048 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Complex1_LYR PF05347.15 KEY65123.1 - 1.2e-16 60.4 0.2 2.1e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY65123.1 - 7.3e-08 33.1 0.0 1.1e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L36 PF00444.18 KEY65124.1 - 3.6e-20 71.9 10.7 4.6e-20 71.5 10.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 KEY65124.1 - 0.42 11.2 5.1 0.88 10.1 5.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L35 PH_6 PF15406.6 KEY65126.1 - 1.8e-40 137.7 1.5 8.2e-40 135.6 1.5 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KEY65126.1 - 0.0066 16.9 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 PH domain HATPase_c PF02518.26 KEY65127.1 - 4.3e-23 82.0 0.1 1e-22 80.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY65127.1 - 7.4e-21 74.4 0.1 1.7e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 KEY65127.1 - 1.3e-10 41.5 0.0 0.00013 22.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KEY65127.1 - 6.6e-08 32.8 0.0 6.6e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 PAS domain HisKA PF00512.25 KEY65127.1 - 4.1e-07 29.9 0.1 4.1e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KEY65127.1 - 2.3e-06 27.6 0.1 0.00045 20.2 0.0 2.8 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 KEY65127.1 - 2.9e-05 24.4 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 2 GAF domain PAS_3 PF08447.12 KEY65127.1 - 0.02 15.2 0.0 0.07 13.4 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KEY65127.1 - 0.038 14.0 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 PAS domain DUF809 PF05663.11 KEY65129.1 - 3.7 7.7 5.5 7.5 6.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Aldedh PF00171.22 KEY65130.1 - 6.6e-161 535.9 0.0 6.6e-161 535.9 0.0 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family RRF PF01765.19 KEY65130.1 - 2.5e-33 115.3 1.8 3.6e-33 114.8 1.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF1487 PF07368.11 KEY65130.1 - 0.0022 17.5 0.0 0.0059 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) SWI-SNF_Ssr4 PF08549.10 KEY65130.1 - 0.14 10.7 7.7 0.23 10.0 7.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Metallophos PF00149.28 KEY65132.1 - 5.4e-34 118.5 0.1 8.1e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEY65132.1 - 4.9e-17 62.1 0.0 9.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUR7 PF06687.12 KEY65133.1 - 9.8e-32 110.3 5.4 1.3e-31 109.9 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.13 KEY65133.1 - 0.0021 16.8 5.7 0.22 10.2 3.5 2.2 2 0 0 2 2 2 2 Tweety Comm PF15957.5 KEY65133.1 - 0.13 12.7 0.2 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Commissureless WD40 PF00400.32 KEY65134.1 - 1.3e-15 57.5 15.3 0.00021 22.0 0.0 9.8 12 0 0 12 12 12 5 WD domain, G-beta repeat WD40_like PF17005.5 KEY65134.1 - 0.002 17.5 0.0 0.0081 15.5 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KEY65134.1 - 0.095 11.3 0.4 29 3.1 0.0 3.7 4 1 0 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEY65134.1 - 0.22 10.2 0.0 8.9 4.9 0.0 3.2 3 0 0 3 3 3 0 Nup133 N terminal like ADH_N PF08240.12 KEY65137.1 - 5e-27 93.9 1.3 8.7e-27 93.2 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY65137.1 - 2.2e-17 63.3 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY65137.1 - 2.1e-05 24.1 0.2 0.0025 17.3 0.2 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KEY65137.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_G PF04718.15 KEY65138.1 - 3.7e-32 111.1 0.8 8e-32 110.1 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Bacteriocin_IIc PF10439.9 KEY65138.1 - 1.8 8.7 9.0 0.88 9.7 4.7 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Methyltransf_23 PF13489.6 KEY65139.1 - 1.3e-14 54.4 0.0 2.7e-14 53.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65139.1 - 2.9e-08 34.3 0.0 5.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KEY65139.1 - 4.5e-06 26.9 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEY65139.1 - 0.00077 19.0 0.0 0.0035 16.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY65139.1 - 0.0011 19.6 0.0 0.0031 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEY65139.1 - 0.0013 18.2 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KEY65139.1 - 0.0013 19.4 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY65139.1 - 0.0045 16.8 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEY65139.1 - 0.0064 16.3 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase GCD14 PF08704.10 KEY65139.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TFIIA PF03153.13 KEY65140.1 - 9.9e-94 315.7 14.4 1.3e-93 315.3 14.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 KEY65140.1 - 0.078 11.6 4.4 0.081 11.6 4.4 1.1 1 0 0 1 1 1 0 Hamartin protein ELM2 PF01448.24 KEY65140.1 - 0.089 13.6 0.1 0.089 13.6 0.1 2.1 2 0 0 2 2 2 0 ELM2 domain FixO PF02433.15 KEY65140.1 - 1.8 8.0 4.9 2.7 7.4 4.9 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO eIF-3_zeta PF05091.12 KEY65140.1 - 3.1 6.7 8.8 4.3 6.2 8.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ANAPC4_WD40 PF12894.7 KEY65141.1 - 6.7e-17 61.6 4.3 3.2e-05 24.1 0.1 4.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY65141.1 - 8e-17 61.3 19.5 0.00032 21.4 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 KEY65141.1 - 3.4e-07 30.3 0.3 0.00021 21.3 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEY65141.1 - 1.4e-06 27.5 0.1 0.00039 19.5 0.0 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_4 PF13418.6 KEY65142.1 - 7e-30 102.8 5.2 2.9e-08 33.6 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEY65142.1 - 4.3e-25 87.2 1.6 3.8e-07 29.9 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KEY65142.1 - 7.8e-24 83.1 2.3 8.5e-05 22.7 0.0 4.7 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KEY65142.1 - 1.7e-21 75.5 0.2 1.4e-05 24.5 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KEY65142.1 - 1.8e-19 68.9 2.2 0.00038 20.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KEY65142.1 - 3.8e-19 68.5 1.0 3.2e-07 30.5 0.1 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain BTB PF00651.31 KEY65142.1 - 3.3e-09 37.0 0.1 5.6e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_aberr PF17017.5 KEY65143.1 - 8.8e-05 22.7 2.0 0.033 14.3 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KEY65143.1 - 0.0011 19.3 15.1 0.096 13.2 0.5 5.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY65143.1 - 0.0059 17.4 12.2 0.29 12.1 0.5 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY65143.1 - 0.22 11.9 5.8 0.8 10.1 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KEY65143.1 - 1.2 9.7 17.7 0.084 13.3 1.0 3.7 4 0 0 4 4 4 0 Zinc-finger double domain HIG_1_N PF04588.13 KEY65144.1 - 8.6e-06 25.9 1.9 2.9e-05 24.2 1.9 1.9 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Romo1 PF10247.9 KEY65144.1 - 0.0087 16.4 2.8 0.016 15.5 2.8 1.4 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 LMWPc PF01451.21 KEY65144.1 - 0.035 14.5 0.2 0.11 12.8 0.2 1.8 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF3861 PF12977.7 KEY65144.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Clc-like PF07062.12 KEY65144.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Clc-like Kelch_1 PF01344.25 KEY65145.1 - 5.1e-41 138.0 18.8 6.6e-09 35.2 0.7 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KEY65145.1 - 1.3e-39 133.5 14.5 3e-07 30.3 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KEY65145.1 - 9.4e-35 118.4 17.2 1.7e-07 31.1 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY65145.1 - 2.1e-34 117.2 11.1 1.7e-07 31.3 0.0 6.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY65145.1 - 7.3e-33 111.8 16.6 2.4e-06 27.6 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KEY65145.1 - 1.1e-32 110.7 16.2 3.1e-08 33.3 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Dus PF01207.17 KEY65146.1 - 3.2e-39 134.9 0.0 2.8e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KEY65146.1 - 0.53 10.4 8.7 2.2 8.4 1.0 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 KEY65146.1 - 1.7 8.7 7.3 9.7 6.2 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEY65146.1 - 8.2 6.3 13.3 1.1 9.1 3.4 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger Peroxin-13_N PF04088.13 KEY65147.1 - 1.2e-50 171.5 0.1 2.5e-50 170.5 0.1 1.6 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KEY65147.1 - 1.5e-09 37.4 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY65147.1 - 6.6e-08 32.0 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY65147.1 - 1.5e-07 31.2 0.1 2.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KEY65147.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain LigD_N PF13298.6 KEY65148.1 - 1.1e-22 80.3 0.1 1.4e-17 63.8 0.0 2.6 1 1 1 2 2 2 2 DNA polymerase Ligase (LigD) Macoilin PF09726.9 KEY65148.1 - 6.5 5.2 5.2 10 4.6 5.2 1.2 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 KEY65149.1 - 2e-16 60.0 15.1 0.0026 18.6 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65149.1 - 8.2e-16 58.1 0.1 0.0025 18.1 0.0 5.6 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY65149.1 - 3.2e-05 23.9 0.2 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEY65149.1 - 0.02 13.8 0.2 13 4.6 0.0 3.3 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEY65149.1 - 0.26 11.3 4.0 2.7 8.0 0.3 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.27 KEY65150.1 - 1.7e-52 177.6 0.0 1.2e-29 103.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY65150.1 - 7.7e-43 147.1 18.7 1.6e-31 110.0 5.1 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY65150.1 - 8.3e-11 41.7 0.0 3.9e-05 23.2 0.0 4.2 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY65150.1 - 3.6e-05 24.2 0.4 0.032 14.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY65150.1 - 0.00043 20.2 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KEY65150.1 - 0.00062 20.0 0.1 3 8.1 0.0 3.6 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KEY65150.1 - 0.00071 19.6 0.7 0.16 12.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KEY65150.1 - 0.0016 17.6 0.1 0.16 11.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KEY65150.1 - 0.0035 16.9 0.0 0.29 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY65150.1 - 0.0043 16.8 2.0 1.2 9.0 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY65150.1 - 0.024 14.5 4.7 11 5.8 0.6 3.5 2 2 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 KEY65150.1 - 0.025 13.8 0.2 0.38 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KEY65150.1 - 0.036 14.6 3.4 0.46 11.0 0.4 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEY65150.1 - 0.044 13.9 2.7 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KEY65150.1 - 0.05 13.3 0.1 2.8 7.6 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein MeaB PF03308.16 KEY65150.1 - 0.086 11.8 0.1 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KEY65150.1 - 0.096 13.1 0.1 78 3.7 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.6 KEY65150.1 - 0.11 12.2 0.8 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KEY65150.1 - 0.16 12.2 0.1 23 5.3 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEY65151.1 - 0.00021 21.7 0.0 0.00039 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEY65151.1 - 0.00037 20.9 0.0 0.00078 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KEY65151.1 - 0.052 12.7 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPK2 PF03976.14 KEY65151.1 - 0.12 11.9 0.0 0.72 9.3 0.0 2.0 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) APG6 PF04111.12 KEY65152.1 - 1.2e-72 243.6 0.0 1.9e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KEY65152.1 - 2.3e-38 131.7 11.5 3.4e-38 131.2 11.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C4H2 PF10146.9 KEY65152.1 - 4.9e-05 23.8 0.2 4.9e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 Zinc finger-containing protein FapA PF03961.13 KEY65152.1 - 0.064 11.8 1.8 0.092 11.3 1.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 KEY65152.1 - 0.12 12.2 7.9 0.19 11.5 7.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lipoprotein_6 PF01441.19 KEY65152.1 - 0.16 11.9 1.6 0.27 11.2 1.6 1.3 1 0 0 1 1 1 0 Lipoprotein PHM7_cyt PF14703.6 KEY65152.1 - 0.17 12.1 1.8 0.32 11.2 1.8 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Seryl_tRNA_N PF02403.22 KEY65152.1 - 0.23 11.7 11.1 0.12 12.6 1.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.6 KEY65152.1 - 0.31 10.6 8.1 0.54 9.8 8.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 KEY65152.1 - 0.41 10.7 9.3 0.85 9.7 9.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KEY65152.1 - 1.9 7.7 9.3 1.2 8.4 6.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.19 KEY65152.1 - 2.6 7.8 16.2 0.92 9.3 12.6 1.7 1 1 0 2 2 2 0 Ezrin/radixin/moesin family KELK PF15796.5 KEY65152.1 - 4.2 7.9 14.3 2.3 8.8 12.0 1.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Scm3 PF10384.9 KEY65153.1 - 3.5e-21 74.7 0.6 1.7e-20 72.5 0.1 2.5 2 0 0 2 2 2 1 Centromere protein Scm3 Pkinase PF00069.25 KEY65154.1 - 5.2e-65 219.4 0.1 6.1e-65 219.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65154.1 - 6.8e-19 68.2 0.0 9.4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY65154.1 - 9.2e-10 38.8 0.0 2.3e-06 27.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY65154.1 - 0.0067 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEY65154.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEY65154.1 - 0.018 14.6 1.2 0.029 13.9 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KEY65154.1 - 0.026 13.8 0.1 0.047 13.0 0.0 1.4 2 0 0 2 2 2 0 Kinase-like DUF3807 PF12720.7 KEY65155.1 - 1.5e-36 126.4 0.6 1.8e-36 126.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HEPN_Toprim_N PF18871.1 KEY65156.1 - 0.019 14.9 1.3 0.023 14.6 1.3 1.1 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 TPR_7 PF13176.6 KEY65156.1 - 1.2 9.4 5.2 0.96 9.6 0.3 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Atg14 PF10186.9 KEY65157.1 - 3.7e-77 259.5 0.0 4.7e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEY65157.1 - 1.5 7.6 6.8 2.2 7.1 6.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KEY65157.1 - 1.8 7.1 3.6 2.5 6.6 3.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 KEY65157.1 - 6.3 7.2 7.9 0.65 10.4 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KEY65157.1 - 8 6.5 10.7 0.24 11.5 2.7 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7_N PF15402.6 KEY65159.1 - 2.5e-199 664.8 100.1 5e-181 604.2 79.4 2.8 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KEY65159.1 - 1.2e-122 408.7 9.2 1.2e-122 408.7 9.2 2.6 2 1 1 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KEY65159.1 - 6.5e-20 71.0 0.3 1.5e-19 69.8 0.3 1.7 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17_N PF16205.5 KEY65160.1 - 4.8e-33 113.4 0.2 7.9e-33 112.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KEY65160.1 - 2.8e-27 94.6 0.6 5.5e-27 93.7 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1719 PF08224.11 KEY65161.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Prefoldin_3 PF13758.6 KEY65163.1 - 2e-29 101.5 0.6 2e-29 101.5 0.6 1.9 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KEY65163.1 - 1.5e-23 83.4 0.1 1.5e-23 83.4 0.1 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.20 KEY65163.1 - 0.00071 19.5 0.5 0.033 14.2 0.1 3.0 2 0 0 2 2 2 1 Prefoldin subunit ABC_tran_CTD PF16326.5 KEY65163.1 - 0.012 15.9 3.7 0.022 15.0 0.2 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4094 PF13334.6 KEY65163.1 - 0.046 14.2 0.0 0.17 12.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TMF_DNA_bd PF12329.8 KEY65163.1 - 0.07 13.1 1.6 7.5 6.6 0.1 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 KEY65163.1 - 0.08 12.9 1.7 0.33 10.9 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit FAA_hydro_N_2 PF18288.1 KEY65163.1 - 0.19 12.2 0.8 0.51 10.8 0.2 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF2057 PF09829.9 KEY65163.1 - 0.43 10.7 4.0 0.63 10.2 2.7 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Fib_alpha PF08702.10 KEY65163.1 - 1.9 8.6 5.9 0.75 10.0 1.0 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KEY65163.1 - 2.3 8.9 6.6 0.82 10.3 0.2 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GFA PF04828.14 KEY65164.1 - 1.1e-13 51.3 1.4 1.3e-06 28.7 1.0 2.8 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Mur_ligase_M PF08245.12 KEY65164.1 - 3.9e-05 23.7 0.0 0.00018 21.5 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEY65164.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain zf-CSL PF05207.13 KEY65164.1 - 0.36 10.6 2.6 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 CSL zinc finger Methyltransf_13 PF08421.11 KEY65164.1 - 0.63 10.3 0.0 0.63 10.3 0.0 2.8 3 0 0 3 3 3 0 Putative zinc binding domain Mitofilin PF09731.9 KEY65165.1 - 5.7e-142 474.7 27.5 4.8e-122 408.9 22.9 2.2 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Mur_ligase_M PF08245.12 KEY65165.1 - 0.039 13.9 1.6 0.27 11.2 0.2 2.9 2 1 0 2 2 2 0 Mur ligase middle domain Ras PF00071.22 KEY65166.1 - 5.6e-58 195.1 0.1 6.4e-58 194.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY65166.1 - 6.9e-36 123.1 0.2 1.2e-35 122.4 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY65166.1 - 7.7e-15 54.8 0.0 9.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEY65166.1 - 1.1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEY65166.1 - 2.1e-06 27.4 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEY65166.1 - 2.7e-06 27.4 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY65166.1 - 5e-05 23.3 1.1 0.14 12.0 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KEY65166.1 - 0.026 14.9 0.3 0.053 13.9 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KEY65166.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KEY65166.1 - 0.15 11.2 0.2 1.8 7.6 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit GbpA_2 PF18416.1 KEY65166.1 - 0.24 11.7 1.2 6.1 7.2 1.2 2.3 1 1 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 Syja_N PF02383.18 KEY65167.1 - 4.4e-88 295.7 0.0 5.6e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PP2C PF00481.21 KEY65168.1 - 1.8e-56 191.7 0.0 2.9e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KEY65168.1 - 8.1e-41 137.6 65.8 3e-12 46.1 0.5 10.3 4 3 7 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KEY65168.1 - 1.2e-37 127.3 73.0 7.8e-05 23.0 0.6 13.1 10 2 3 14 14 14 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KEY65168.1 - 2.6e-27 95.6 0.1 6.7e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KEY65168.1 - 8.5e-21 73.4 3.2 3.1e-20 71.6 3.2 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KEY65168.1 - 0.00033 20.8 54.1 4.5 8.2 1.3 16.6 17 2 0 17 17 17 1 Leucine Rich Repeat LRR_9 PF14580.6 KEY65168.1 - 0.0016 18.0 19.1 0.5 9.9 0.1 4.4 2 1 1 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KEY65168.1 - 0.0076 16.2 0.6 4.3 7.3 0.2 3.8 3 1 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) Glyco_transf_22 PF03901.17 KEY65169.1 - 1.9e-39 136.1 16.3 2.5e-39 135.7 16.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family O_anti_polymase PF01901.16 KEY65169.1 - 0.00081 18.7 0.8 0.0018 17.6 0.8 1.5 1 0 0 1 1 1 1 Putative O-antigen polymerase Yos1 PF08571.10 KEY65170.1 - 1.1e-30 105.7 1.4 1.2e-30 105.6 1.4 1.0 1 0 0 1 1 1 1 Yos1-like BTRD1 PF17660.1 KEY65170.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 UCH PF00443.29 KEY65171.1 - 1.8e-53 181.7 0.1 2.8e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY65171.1 - 1.5e-24 87.2 1.5 1.4e-19 70.9 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KEY65171.1 - 0.0045 16.5 2.5 0.24 10.8 0.5 2.6 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CBS PF00571.28 KEY65173.1 - 5.1e-08 33.2 0.0 0.0058 17.1 0.0 3.2 1 1 2 3 3 3 3 CBS domain Epimerase PF01370.21 KEY65175.1 - 6.1e-19 68.4 0.0 7.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY65175.1 - 2.4e-07 30.2 0.0 3.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEY65175.1 - 2.9e-05 23.6 0.0 6.4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KEY65175.1 - 0.0034 17.5 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEY65175.1 - 0.0059 15.6 0.0 0.021 13.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEY65175.1 - 0.0066 15.9 0.0 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KEY65175.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KEY65175.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KEY65175.1 - 0.096 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F_actin_cap_B PF01115.17 KEY65176.1 - 9.7e-105 349.5 0.0 1.1e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit APH PF01636.23 KEY65177.1 - 2.5e-13 50.5 0.0 1.1e-12 48.4 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family FANCL_C PF11793.8 KEY65178.1 - 0.0039 17.3 0.9 0.0099 16.0 0.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 KEY65178.1 - 0.011 15.6 0.9 0.011 15.6 0.9 1.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 KEY65178.1 - 0.023 14.9 1.0 0.077 13.3 0.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Pribosyl_synth PF14572.6 KEY65179.1 - 5.1e-43 147.2 0.6 1.1e-35 123.3 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KEY65179.1 - 2.1e-39 134.1 0.1 4.9e-39 132.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KEY65179.1 - 7.7e-15 54.8 0.3 1.9e-14 53.5 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEY65179.1 - 0.003 17.1 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4392 PF14336.6 KEY65179.1 - 0.069 12.6 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) ATG22 PF11700.8 KEY65180.1 - 2.6e-191 636.4 10.7 3e-191 636.2 10.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TRAP-gamma PF07074.12 KEY65180.1 - 0.0032 17.0 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3602 PF12223.8 KEY65181.1 - 5.4e-23 81.4 17.7 2.1e-22 79.5 10.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CHORD PF04968.12 KEY65182.1 - 1.8e-48 163.1 21.4 5.2e-25 87.9 6.8 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KEY65182.1 - 4e-13 50.2 0.1 6.6e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 CS domain CAP_N PF01213.19 KEY65182.1 - 1.7 8.1 5.4 2.5 7.5 5.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF836 PF05768.14 KEY65183.1 - 7e-13 48.8 0.0 8.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KEY65183.1 - 0.00013 22.1 0.0 0.00033 20.8 0.0 1.8 1 1 1 2 2 2 1 Glutaredoxin TraF PF13728.6 KEY65183.1 - 0.081 12.7 0.1 0.24 11.2 0.0 1.7 1 1 0 2 2 2 0 F plasmid transfer operon protein HpcH_HpaI PF03328.14 KEY65184.1 - 6.7e-35 120.2 0.0 8e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SHS2_Rpb7-N PF03876.17 KEY65185.1 - 3.3e-15 56.2 0.0 5.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KEY65185.1 - 2.5e-13 50.1 0.0 3.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KEY65186.1 - 1.8e-27 95.3 0.0 3.1e-27 94.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) NPL4 PF05021.15 KEY65188.1 - 2e-141 470.8 0.0 2.5e-141 470.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KEY65188.1 - 3.5e-67 225.1 0.0 6.3e-67 224.2 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KEY65188.1 - 0.0019 18.6 0.0 0.0076 16.7 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KEY65189.1 - 4.1e-80 267.6 0.3 4.8e-80 267.4 0.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KEY65189.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Mst1_SARAH PF11629.8 KEY65189.1 - 0.25 11.4 1.8 0.98 9.6 0.1 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DMPK_coil PF08826.10 KEY65189.1 - 0.32 11.1 4.9 0.57 10.3 0.4 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like SF-assemblin PF06705.11 KEY65189.1 - 0.67 9.2 5.9 2.5 7.4 4.3 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin ORC3_N PF07034.11 KEY65191.1 - 4.8e-38 131.1 5.3 9.3e-36 123.6 5.3 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KEY65191.1 - 5.4e-25 88.1 0.1 2.6e-14 53.5 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal AP4E_app_platf PF14807.6 KEY65191.1 - 0.15 12.4 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Ribosomal_L21p PF00829.21 KEY65192.1 - 4.1e-13 49.5 0.0 5.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.22 KEY65193.1 - 1.7e-45 154.6 2.0 3.1e-45 153.7 2.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 KEY65193.1 - 0.22 9.8 6.9 0.27 9.5 6.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 DUF4718 PF15842.5 KEY65193.1 - 0.53 10.1 3.2 0.77 9.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) SRP-alpha_N PF04086.13 KEY65193.1 - 5.3 6.9 11.9 6.7 6.5 11.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal UQ_con PF00179.26 KEY65194.1 - 1e-26 93.2 0.2 1.7e-12 47.2 0.1 2.9 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY65194.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Rep_fac_C PF08542.11 KEY65195.1 - 7.9e-20 71.1 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KEY65195.1 - 3.8e-17 62.9 0.0 2.3e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KEY65195.1 - 7.1e-13 48.7 0.0 6.5e-12 45.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KEY65195.1 - 3e-09 37.1 0.0 8.6e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KEY65195.1 - 3.2e-06 27.0 0.1 1.3e-05 25.0 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KEY65195.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KEY65195.1 - 1.2e-05 25.8 0.0 0.0006 20.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY65195.1 - 1.6e-05 25.2 0.0 0.0003 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KEY65195.1 - 1.8e-05 25.0 0.0 6.8e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KEY65195.1 - 4.4e-05 23.4 0.1 0.00011 22.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEY65195.1 - 0.00014 21.4 0.0 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KEY65195.1 - 0.00031 20.8 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEY65195.1 - 0.002 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KEY65195.1 - 0.0027 18.0 0.0 0.019 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEY65195.1 - 0.0046 16.2 0.0 0.0099 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KEY65195.1 - 0.0047 16.5 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KEY65195.1 - 0.0048 16.9 0.1 0.035 14.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEY65195.1 - 0.0055 16.5 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY65195.1 - 0.0078 15.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KEY65195.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KEY65195.1 - 0.034 14.0 0.0 0.16 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KEY65195.1 - 0.035 14.1 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KEY65195.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KEY65195.1 - 0.049 14.2 0.0 0.16 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KEY65195.1 - 0.078 12.7 0.3 0.78 9.5 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KEY65195.1 - 0.089 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_C47 PF05543.13 KEY65195.1 - 0.12 11.9 0.0 0.75 9.3 0.0 2.2 3 1 0 3 3 3 0 Staphopain peptidase C47 DUF4407 PF14362.6 KEY65196.1 - 0.23 10.8 7.9 0.044 13.1 3.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Troponin PF00992.20 KEY65196.1 - 0.38 11.0 6.3 0.71 10.2 4.8 2.2 1 1 1 2 2 2 0 Troponin Mod_r PF07200.13 KEY65196.1 - 2.8 8.0 21.2 2.7 8.1 0.7 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 KEY65196.1 - 4.1 7.9 4.8 11 6.4 0.5 3.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Sec63 PF02889.16 KEY65197.1 - 1.2e-164 545.6 0.1 2e-92 309.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KEY65197.1 - 2.2e-52 177.4 0.1 2.1e-29 102.6 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KEY65197.1 - 1.7e-34 118.3 1.3 1.7e-34 118.3 1.3 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 KEY65197.1 - 4.5e-24 85.4 0.0 9.4e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY65197.1 - 2.3e-11 44.0 0.0 8.2e-08 32.6 0.0 3.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEY65197.1 - 9.2e-07 29.2 0.1 0.017 15.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KEY65197.1 - 0.0005 19.2 0.0 0.39 9.7 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KEY65197.1 - 0.0027 17.2 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein TFIIE_alpha PF02002.17 KEY65197.1 - 0.029 14.2 0.2 1.3 8.9 0.0 3.3 2 0 0 2 2 2 0 TFIIE alpha subunit UvrD-helicase PF00580.21 KEY65197.1 - 0.28 10.6 3.5 2 7.9 0.0 2.9 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PWWP PF00855.17 KEY65198.1 - 3.1e-15 56.4 0.7 1.1e-14 54.5 0.0 2.4 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 KEY65198.1 - 0.0052 16.8 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Peptidase_M1 PF01433.20 KEY65199.1 - 1.5e-44 152.2 1.5 2.1e-44 151.7 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KEY65199.1 - 4e-38 130.0 0.0 8e-38 129.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KEY65199.1 - 3.4e-30 105.6 0.0 6.6e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KEY65199.1 - 0.00043 20.0 0.3 0.044 13.5 0.0 2.8 3 0 0 3 3 3 1 Peptidase MA superfamily TbpB_B_D PF01298.18 KEY65199.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Peptidase_M61 PF05299.12 KEY65199.1 - 0.43 11.0 2.2 9.1 6.7 2.2 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Kinesin PF00225.23 KEY65200.1 - 3.9e-111 371.2 0.0 7.4e-111 370.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KEY65200.1 - 1.1e-49 169.1 0.2 2.8e-49 167.7 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KEY65200.1 - 3.5e-35 121.8 15.5 4e-31 108.5 0.2 3.9 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KEY65200.1 - 4.4e-25 88.4 0.3 1.3e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 KEY65200.1 - 9.2e-07 29.1 0.1 8.2e-06 26.1 0.2 2.7 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KEY65200.1 - 1e-06 29.1 0.1 4.9e-06 26.9 0.1 2.3 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KEY65200.1 - 0.041 14.4 0.0 1.2 9.6 0.0 2.7 1 1 0 1 1 1 0 PH domain AAA_22 PF13401.6 KEY65200.1 - 0.13 12.6 0.0 0.56 10.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain Erp_C PF06780.11 KEY65200.1 - 0.13 12.2 8.7 0.48 10.4 8.7 1.9 1 0 0 1 1 1 0 Erp protein C-terminus Exonuc_VII_L PF02601.15 KEY65200.1 - 1.4 8.4 10.9 3.7 7.0 8.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KEY65200.1 - 2.5 8.1 19.1 6 6.9 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PEP-utilisers_N PF05524.13 KEY65200.1 - 8 6.7 9.1 8.3 6.6 3.2 2.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal HEAT PF02985.22 KEY65202.1 - 5.5e-10 38.6 0.4 0.11 12.8 0.0 5.0 4 1 0 4 4 4 3 HEAT repeat Pkinase PF00069.25 KEY65202.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF2462 PF09495.10 KEY65202.1 - 2.1e-08 34.8 15.3 8.5e-08 32.8 15.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) HEAT_EZ PF13513.6 KEY65202.1 - 1e-07 32.3 0.1 0.00025 21.5 0.1 3.1 2 0 0 2 2 2 2 HEAT-like repeat Pkinase_Tyr PF07714.17 KEY65202.1 - 3e-07 30.0 0.0 4.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KEY65202.1 - 1.6e-05 25.0 0.0 6.8e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY65202.1 - 3.5e-05 24.1 0.4 0.00029 21.1 0.1 2.7 2 1 1 3 3 3 2 HEAT repeats DUF3439 PF11921.8 KEY65202.1 - 0.49 10.4 6.4 1 9.3 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pyridoxal_deC PF00282.19 KEY65203.1 - 1.5e-23 83.2 0.0 2.3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KEY65203.1 - 0.00016 21.0 0.0 0.00032 20.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEY65203.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cyt-b5 PF00173.28 KEY65204.1 - 3.6e-23 81.5 0.6 4e-23 81.4 0.6 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nuclease_act PF08133.11 KEY65204.1 - 0.0031 17.6 0.0 0.0097 16.0 0.0 1.7 2 0 0 2 2 2 1 Anticodon nuclease activator family RE_LlaJI PF09563.10 KEY65204.1 - 0.051 12.8 0.1 0.057 12.6 0.1 1.0 1 0 0 1 1 1 0 LlaJI restriction endonuclease Peptidase_M48 PF01435.18 KEY65205.1 - 7.2e-36 123.8 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 UPF0126 PF03458.13 KEY65205.1 - 0.086 12.7 7.2 0.71 9.8 4.6 3.2 2 1 0 2 2 2 0 UPF0126 domain Methyltransf_23 PF13489.6 KEY65206.1 - 1.4e-14 54.3 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65206.1 - 5.6e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY65206.1 - 0.01 16.6 0.0 0.12 13.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEY65206.1 - 0.029 13.7 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aconitase PF00330.20 KEY65207.1 - 3.2e-143 478.1 0.0 3.9e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEY65207.1 - 1.5e-37 128.8 0.0 2.4e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KEY65207.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Nucleopor_Nup85 PF07575.13 KEY65208.1 - 2.4e-16 59.5 0.0 3.9e-15 55.4 0.0 2.2 1 1 0 1 1 1 1 Nup85 Nucleoporin TERB2 PF15101.6 KEY65208.1 - 0.22 11.5 0.6 0.41 10.7 0.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIIAH PF12685.7 KEY65208.1 - 0.65 9.8 8.8 1.7 8.4 8.8 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 KEY65208.1 - 0.68 9.3 30.0 1.4 8.3 30.0 1.4 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KEY65208.1 - 4.9 5.8 11.7 8.3 5.1 11.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ADH_N PF08240.12 KEY65209.1 - 5e-26 90.7 2.0 1.2e-25 89.5 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY65209.1 - 4.4e-20 72.0 0.5 8.5e-20 71.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEY65209.1 - 0.00078 18.8 0.5 0.0014 18.0 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KEY65209.1 - 0.0024 17.4 0.2 0.0064 16.0 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY65209.1 - 0.036 15.1 0.0 0.061 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KEY65209.1 - 0.044 13.3 0.1 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HhH-GPD PF00730.25 KEY65210.1 - 2.1e-13 50.7 0.0 2.2e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEY65210.1 - 3.9e-08 32.8 0.0 9.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Med3 PF11593.8 KEY65210.1 - 1.4 8.1 3.4 2 7.5 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Gln-synt_C PF00120.24 KEY65211.1 - 4.2e-15 55.6 0.0 9.9e-11 41.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEY65211.1 - 1.1e-13 50.8 0.0 1.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PgaD PF13994.6 KEY65212.1 - 0.0016 18.5 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 PgaD-like protein CorA PF01544.18 KEY65212.1 - 0.0019 17.6 0.2 0.0049 16.2 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein 7tm_3 PF00003.22 KEY65212.1 - 0.068 12.9 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR LMBR1 PF04791.16 KEY65213.1 - 7.5e-112 374.8 11.1 8.7e-112 374.6 11.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein SAS4 PF15460.6 KEY65213.1 - 0.048 13.7 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Hat1_N PF10394.9 KEY65214.1 - 8.6e-46 156.1 0.0 1.5e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KEY65214.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MukF_M PF17192.4 KEY65214.1 - 0.12 12.1 0.6 0.23 11.2 0.6 1.4 1 0 0 1 1 1 0 MukF middle domain GAS PF13851.6 KEY65214.1 - 0.78 9.1 5.8 1.1 8.5 5.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CTK3 PF12243.8 KEY65215.1 - 1.2e-47 160.9 0.0 1.8e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KEY65215.1 - 1.6e-15 57.0 11.0 1.6e-15 57.0 11.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus KMP11 PF03037.16 KEY65215.1 - 1.7 9.5 5.1 1.8 9.4 1.4 2.3 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Ribosomal_L12 PF00542.19 KEY65216.1 - 1.2e-19 70.4 3.8 1.2e-19 70.4 3.8 2.5 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KEY65216.1 - 3.6e-14 52.2 6.5 6.1e-14 51.5 4.1 2.7 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KEY65216.1 - 0.084 12.7 1.6 0.11 12.2 0.6 1.8 2 0 0 2 2 2 0 Stage VI sporulation protein F HMGL-like PF00682.19 KEY65216.1 - 0.15 11.6 1.3 0.75 9.3 0.0 2.0 1 1 1 2 2 2 0 HMGL-like AAA_5 PF07728.14 KEY65217.1 - 7.6e-123 405.0 0.0 1.6e-21 76.8 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KEY65217.1 - 1.2e-55 186.2 5.6 3.5e-24 85.1 0.0 6.1 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KEY65217.1 - 1.6e-30 105.3 0.1 1.3e-29 102.4 0.0 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KEY65217.1 - 6.2e-28 97.3 0.0 6.3e-10 39.0 0.0 7.1 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KEY65217.1 - 1.3e-26 93.6 0.1 0.00011 22.6 0.0 6.9 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KEY65217.1 - 4.6e-26 91.2 0.0 0.0015 18.7 0.0 8.6 8 1 0 8 8 8 4 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KEY65217.1 - 5.1e-26 91.3 2.8 6.1e-05 22.6 0.0 6.9 6 1 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 KEY65217.1 - 4.4e-25 89.0 18.6 0.00034 21.0 0.3 9.9 8 2 1 9 9 7 6 AAA ATPase domain AAA_6 PF12774.7 KEY65217.1 - 7.8e-22 77.7 0.0 0.0099 14.9 0.0 8.2 8 0 0 8 8 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KEY65217.1 - 2.7e-20 73.0 1.4 0.004 17.4 0.0 8.8 8 0 0 8 8 7 5 AAA domain Sigma54_activat PF00158.26 KEY65217.1 - 1.5e-17 63.8 0.0 0.045 13.4 0.0 5.6 5 0 0 5 5 5 5 Sigma-54 interaction domain AAA_18 PF13238.6 KEY65217.1 - 6.6e-16 59.0 0.2 0.017 15.7 0.0 6.8 6 0 0 6 6 5 2 AAA domain TsaE PF02367.17 KEY65217.1 - 1.4e-15 57.4 1.7 0.018 15.1 0.0 5.8 6 0 0 6 6 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEY65217.1 - 3.1e-15 56.6 0.1 0.063 13.4 0.0 6.4 6 0 0 6 6 5 4 AAA domain AAA_14 PF13173.6 KEY65217.1 - 1.3e-13 51.1 0.0 0.005 16.9 0.0 6.1 6 0 0 6 6 5 2 AAA domain T2SSE PF00437.20 KEY65217.1 - 3.3e-13 49.3 0.6 0.038 13.0 0.0 5.6 5 0 0 5 5 5 3 Type II/IV secretion system protein RuvB_N PF05496.12 KEY65217.1 - 1.8e-11 44.0 3.2 0.02 14.6 0.0 6.5 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEY65217.1 - 3.6e-11 43.4 2.9 0.21 12.0 0.0 6.6 6 0 0 6 6 5 2 RNA helicase RsgA_GTPase PF03193.16 KEY65217.1 - 8e-11 42.1 1.5 0.28 11.1 0.2 5.9 6 0 0 6 6 5 2 RsgA GTPase Zeta_toxin PF06414.12 KEY65217.1 - 1.4e-10 40.8 6.9 0.0066 15.8 0.0 6.5 7 0 0 7 7 6 2 Zeta toxin Sigma54_activ_2 PF14532.6 KEY65217.1 - 1.9e-10 41.0 0.1 0.0019 18.3 0.0 5.6 5 0 0 5 5 5 2 Sigma-54 interaction domain NACHT PF05729.12 KEY65217.1 - 8.2e-10 38.8 7.4 0.11 12.4 0.1 5.5 5 0 0 5 5 4 3 NACHT domain Rad17 PF03215.15 KEY65217.1 - 3.4e-09 36.9 0.3 0.37 10.7 0.0 5.7 5 0 0 5 5 5 2 Rad17 P-loop domain IstB_IS21 PF01695.17 KEY65217.1 - 4.9e-09 36.2 0.2 0.19 11.4 0.0 5.7 6 0 0 6 6 5 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEY65217.1 - 6.3e-08 32.3 0.7 5.7 6.3 0.0 6.8 7 0 0 7 7 7 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KEY65217.1 - 1e-07 31.7 2.4 0.35 10.4 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.6 KEY65217.1 - 3.5e-07 30.7 3.0 6.3 7.1 0.1 6.4 6 0 0 6 6 5 0 AAA domain AAA_29 PF13555.6 KEY65217.1 - 3.7e-07 29.8 0.1 3.1 7.6 0.0 5.9 5 0 0 5 5 5 1 P-loop containing region of AAA domain TniB PF05621.11 KEY65217.1 - 7.7e-07 28.7 0.2 5.1 6.5 0.0 5.6 5 0 0 5 5 5 0 Bacterial TniB protein ATPase_2 PF01637.18 KEY65217.1 - 1.2e-06 28.6 0.0 1.5 8.7 0.0 5.6 6 0 0 6 6 5 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KEY65217.1 - 3.9e-06 26.2 1.3 3.1 6.9 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) SRP54 PF00448.22 KEY65217.1 - 4.8e-06 26.3 5.0 0.64 9.6 0.1 5.2 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KEY65217.1 - 8e-06 25.9 7.2 0.92 9.4 0.1 5.6 6 0 0 6 6 5 1 NTPase ABC_tran PF00005.27 KEY65217.1 - 8.1e-06 26.4 13.9 0.065 13.7 0.0 6.6 6 1 0 6 6 5 2 ABC transporter PduV-EutP PF10662.9 KEY65217.1 - 8.4e-06 25.6 3.2 0.12 12.2 0.0 4.6 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 KEY65217.1 - 3.1e-05 24.0 7.5 3.6 7.5 0.0 6.6 7 0 0 7 7 5 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KEY65217.1 - 6.1e-05 22.8 2.8 7.4 6.2 0.2 6.1 6 1 0 6 6 5 0 AAA domain dNK PF01712.19 KEY65217.1 - 0.00011 22.2 5.1 15 5.4 0.0 5.4 5 0 0 5 5 5 0 Deoxynucleoside kinase AAA_28 PF13521.6 KEY65217.1 - 0.00011 22.5 17.0 0.74 10.0 0.1 6.6 7 0 0 7 7 6 1 AAA domain Bac_DnaA PF00308.18 KEY65217.1 - 0.00014 21.8 0.6 8.3 6.2 0.0 5.6 6 0 0 6 6 5 0 Bacterial dnaA protein VWA PF00092.28 KEY65217.1 - 0.00028 21.2 0.1 0.00096 19.4 0.1 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain MMR_HSR1 PF01926.23 KEY65217.1 - 0.00032 20.7 0.9 47 4.1 0.0 4.8 4 0 0 4 4 4 0 50S ribosome-binding GTPase GAF_2 PF13185.6 KEY65217.1 - 0.00036 20.9 0.0 0.15 12.4 0.0 3.6 3 0 0 3 3 2 1 GAF domain CbiA PF01656.23 KEY65217.1 - 0.00054 20.0 3.7 2.1 8.4 0.0 5.7 6 0 0 6 6 5 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KEY65217.1 - 0.0009 18.7 0.2 13 5.0 0.0 4.8 5 0 0 5 5 5 0 KaiC Viral_helicase1 PF01443.18 KEY65217.1 - 0.0018 18.1 0.2 26 4.5 0.0 4.7 5 0 0 5 5 3 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KEY65217.1 - 0.0019 18.4 3.3 3.8 7.7 0.1 5.0 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 KEY65217.1 - 0.0025 17.6 0.7 14 5.3 0.0 4.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family VWA_2 PF13519.6 KEY65217.1 - 0.0064 17.1 0.0 0.038 14.6 0.0 2.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DEAD PF00270.29 KEY65217.1 - 0.013 15.3 2.1 20 4.9 0.0 5.0 6 0 0 6 6 5 0 DEAD/DEAH box helicase PhoH PF02562.16 KEY65217.1 - 0.013 14.9 1.3 17 4.8 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 KEY65217.1 - 0.014 14.8 1.1 11 5.2 0.0 4.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family Y_phosphatase PF00102.27 KEY65217.1 - 0.051 13.1 0.1 37 3.8 0.0 4.0 4 0 0 4 4 4 0 Protein-tyrosine phosphatase MeaB PF03308.16 KEY65217.1 - 0.097 11.6 0.3 11 4.9 0.1 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KEY65217.1 - 0.14 11.7 7.6 26 4.3 0.1 5.5 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KEY65217.1 - 0.36 10.6 9.4 25 4.6 0.1 4.7 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KEY65217.1 - 0.58 10.0 4.1 58 3.6 0.2 4.6 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B Isochorismatase PF00857.20 KEY65218.1 - 2.3e-20 73.5 0.1 3.4e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Isochorismatase family RETICULATA-like PF11891.8 KEY65218.1 - 0.072 12.9 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein RETICULATA-related DUF919 PF06034.11 KEY65219.1 - 0.22 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Lipase_GDSL_2 PF13472.6 KEY65220.1 - 4e-18 66.4 0.0 6.8e-18 65.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY65220.1 - 4.3e-16 59.5 0.0 5.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BP28CT PF08146.12 KEY65221.1 - 4.7e-42 143.5 0.2 3.2e-41 140.8 0.0 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KEY65221.1 - 4.8e-25 88.2 0.2 4.8e-25 88.2 0.2 5.3 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KEY65221.1 - 1.4e-05 24.9 13.5 0.0087 16.2 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KEY65221.1 - 0.0012 19.2 14.0 0.31 11.5 0.0 6.0 5 1 1 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 KEY65221.1 - 0.068 13.4 1.6 2.5 8.3 0.1 3.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KEY65221.1 - 0.2 12.2 14.4 0.8 10.3 0.1 6.4 5 1 1 6 6 6 0 HEAT-like repeat HK PF02110.15 KEY65222.1 - 1.5e-71 240.7 4.1 4.4e-71 239.2 4.1 1.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Pyr_redox_2 PF07992.14 KEY65222.1 - 1.5e-44 152.5 1.5 8.5e-44 149.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TMP-TENI PF02581.17 KEY65222.1 - 2.2e-40 137.9 1.0 4e-40 137.1 1.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Pyr_redox PF00070.27 KEY65222.1 - 6.2e-12 45.9 0.1 1.4e-09 38.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY65222.1 - 0.00037 19.8 0.6 0.23 10.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Carb_kinase PF01256.17 KEY65222.1 - 0.012 15.2 0.1 0.035 13.6 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate kinase NAD_binding_8 PF13450.6 KEY65222.1 - 0.026 14.7 0.0 17 5.7 0.0 3.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N PF00107.26 KEY65222.1 - 0.055 13.5 1.4 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Aminotran_1_2 PF00155.21 KEY65223.1 - 3.2e-83 279.9 0.0 4e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY65223.1 - 4.1e-05 22.3 0.0 6.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEY65223.1 - 0.00032 19.7 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEY65223.1 - 0.003 16.9 0.2 0.0049 16.2 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 KEY65223.1 - 0.0038 15.9 0.8 0.0058 15.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) RVT_1 PF00078.27 KEY65224.1 - 3.2e-38 131.5 0.0 5.4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KEY65224.1 - 0.00084 19.2 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like APG6_N PF17675.1 KEY65225.1 - 0.0034 17.9 13.7 0.0061 17.1 13.7 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 KEY65225.1 - 0.0048 17.0 12.1 0.0052 16.9 12.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus SIL1 PF16782.5 KEY65225.1 - 0.0052 16.0 3.3 0.0053 16.0 3.3 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 OmpH PF03938.14 KEY65225.1 - 0.015 15.7 18.4 0.015 15.7 18.4 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FapA PF03961.13 KEY65225.1 - 0.13 10.8 7.7 0.14 10.7 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PEP-utilisers_N PF05524.13 KEY65225.1 - 0.23 11.6 5.4 0.15 12.3 3.4 1.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PV-1 PF06637.11 KEY65225.1 - 0.32 9.8 9.1 0.42 9.4 9.1 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Ly49 PF08391.10 KEY65225.1 - 0.74 10.2 8.7 1.1 9.6 8.7 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF948 PF06103.11 KEY65225.1 - 0.74 10.1 3.6 2.6 8.3 3.1 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-PARP PF00645.18 KEY65229.1 - 3.3e-21 75.9 0.7 3.3e-21 75.9 0.7 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PC4 PF02229.16 KEY65229.1 - 0.05 13.3 0.3 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.11 KEY65229.1 - 9.4 7.0 56.3 4.7 8.0 25.7 3.5 1 1 2 3 3 3 0 DTHCT (NUC029) region PI3_PI4_kinase PF00454.27 KEY65230.1 - 5.8e-49 167.2 0.0 1.1e-48 166.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEY65230.1 - 7.5e-33 114.2 2.0 1.7e-32 113.0 2.0 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KEY65230.1 - 4.1e-30 103.7 0.2 5.5e-29 100.1 0.0 3.2 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KEY65230.1 - 2.7e-15 55.9 0.0 5.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 FATC domain HSP70 PF00012.20 KEY65230.1 - 2.5e-07 29.3 0.0 1.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 KEY65230.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family IFRD PF05004.13 KEY65230.1 - 0.53 9.3 2.9 17 4.4 0.0 3.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) TetR_C_6 PF13977.6 KEY65230.1 - 2.1 8.6 8.3 25 5.1 0.1 4.8 5 0 0 5 5 5 0 BetI-type transcriptional repressor, C-terminal KLRAQ PF10205.9 KEY65231.1 - 0.0069 16.6 9.5 0.012 15.9 9.5 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DHR10 PF18595.1 KEY65231.1 - 0.021 14.9 14.7 0.043 13.9 14.7 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 KEY65231.1 - 0.027 13.4 12.8 0.042 12.7 12.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KEY65231.1 - 0.034 13.7 1.2 0.054 13.1 1.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit KELK PF15796.5 KEY65231.1 - 0.044 14.2 8.5 0.1 13.1 8.5 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fmp27_WPPW PF10359.9 KEY65231.1 - 0.068 12.0 2.3 0.089 11.6 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 KEY65231.1 - 0.069 13.3 10.1 0.11 12.6 10.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HhH-GPD PF00730.25 KEY65231.1 - 0.07 13.6 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein GLE1 PF07817.13 KEY65231.1 - 0.09 12.0 3.2 0.14 11.3 3.2 1.2 1 0 0 1 1 1 0 GLE1-like protein CALCOCO1 PF07888.11 KEY65231.1 - 0.094 11.6 13.2 0.14 11.0 13.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FemAB PF02388.16 KEY65231.1 - 0.11 11.3 6.1 0.17 10.8 6.1 1.1 1 0 0 1 1 1 0 FemAB family APG6_N PF17675.1 KEY65231.1 - 0.12 12.9 11.1 0.21 12.1 11.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 KEY65231.1 - 0.2 12.0 11.0 0.35 11.2 11.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 KEY65231.1 - 0.23 11.5 13.0 0.35 10.9 13.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3037 PF11236.8 KEY65231.1 - 0.28 11.6 1.5 0.8 10.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Golgin_A5 PF09787.9 KEY65231.1 - 0.34 10.3 10.0 0.53 9.7 10.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF724 PF05266.14 KEY65231.1 - 0.52 10.1 8.6 0.82 9.5 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mod_r PF07200.13 KEY65231.1 - 0.73 9.9 13.6 1.3 9.1 13.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NUDE_C PF04880.13 KEY65231.1 - 0.76 10.2 11.9 1.4 9.4 11.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Filament PF00038.21 KEY65231.1 - 0.9 9.1 14.6 3 7.3 12.1 2.0 1 1 1 2 2 2 0 Intermediate filament protein GrpE PF01025.19 KEY65231.1 - 1 9.0 9.1 1.6 8.3 9.1 1.3 1 0 0 1 1 1 0 GrpE Atg14 PF10186.9 KEY65231.1 - 1.4 8.0 9.2 2.3 7.2 9.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KEY65231.1 - 1.4 8.2 7.0 2.1 7.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 KEY65231.1 - 1.7 9.1 10.0 2.8 8.4 10.0 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 KEY65231.1 - 3.4 6.8 5.5 5.6 6.1 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 KEY65231.1 - 3.6 8.3 11.2 12 6.6 11.2 1.9 1 0 0 1 1 1 0 SlyX GGACT PF06094.12 KEY65232.1 - 4.7e-10 40.1 0.0 7.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KEY65232.1 - 0.0002 21.7 0.0 0.0079 16.6 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family FAM75 PF14650.6 KEY65232.1 - 0.021 14.4 14.6 0.037 13.6 14.6 1.3 1 0 0 1 1 1 0 FAM75 family CCDC53 PF10152.9 KEY65232.1 - 0.31 11.4 1.2 1.5 9.3 0.3 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 KEY65232.1 - 7.2 7.3 18.0 1.7 9.3 7.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidoligase_2 PF12224.8 KEY65233.1 - 3.6e-16 59.6 0.0 7e-16 58.7 0.0 1.5 2 0 0 2 2 2 1 Putative amidoligase enzyme CPSase_L_D2 PF02786.17 KEY65234.1 - 1.1e-73 247.2 0.0 2.5e-73 246.1 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEY65234.1 - 3.9e-36 124.0 0.0 1e-35 122.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEY65234.1 - 2.2e-35 121.0 0.0 4.4e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEY65234.1 - 1.1e-15 57.2 1.4 3.6e-15 55.6 1.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEY65234.1 - 1.1e-08 34.7 0.2 0.0018 18.0 0.0 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KEY65234.1 - 3.1e-08 33.4 0.1 7.6e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEY65234.1 - 1.7e-07 31.0 0.0 4.6e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KEY65234.1 - 9.3e-05 23.1 0.0 0.52 11.0 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KEY65234.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KEY65234.1 - 0.022 14.0 0.2 2.9 7.1 0.0 3.0 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KEY65234.1 - 0.083 12.8 0.4 0.74 9.7 0.2 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein LAL_C2 PF18603.1 KEY65234.1 - 0.11 12.7 0.1 0.58 10.4 0.0 2.3 3 0 0 3 3 1 0 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 KEY65234.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Putative_PNPOx PF01243.20 KEY65235.1 - 1.4e-10 41.3 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KEY65235.1 - 0.084 12.9 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.18 KEY65236.1 - 1.3e-51 175.2 4.9 1e-50 172.3 4.9 1.9 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 KEY65237.1 - 2.1e-54 184.6 0.0 7.6e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65237.1 - 8.1e-31 107.2 0.0 7.9e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KEY65237.1 - 0.00027 20.1 0.1 0.00043 19.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KEY65237.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY65237.1 - 0.0066 15.4 0.0 0.0094 14.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEY65237.1 - 0.02 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SUR7 PF06687.12 KEY65238.1 - 1.5e-31 109.7 7.4 1.9e-31 109.4 7.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 KEY65238.1 - 1.1 8.9 16.9 0.19 11.4 12.2 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PGG PF13962.6 KEY65238.1 - 3.9 7.3 12.2 14 5.5 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function BPL_LplA_LipB PF03099.19 KEY65239.1 - 5e-07 29.7 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ALO PF04030.14 KEY65240.1 - 6.2e-88 295.0 0.1 7.8e-88 294.6 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KEY65240.1 - 3.9e-30 104.4 0.0 6e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ABC_tran PF00005.27 KEY65241.1 - 3.8e-43 147.3 0.0 8.9e-23 81.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY65241.1 - 4.1e-27 95.5 28.1 1.2e-22 80.8 16.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY65241.1 - 4.6e-11 42.6 1.4 0.0041 16.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY65241.1 - 6e-07 29.1 0.4 0.034 13.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY65241.1 - 7.4e-07 29.3 6.4 0.16 11.8 0.2 4.4 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEY65241.1 - 1.9e-05 25.1 0.7 0.028 14.8 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEY65241.1 - 3.5e-05 23.8 1.0 0.16 11.9 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEY65241.1 - 0.0007 19.7 2.5 0.46 10.6 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 KEY65241.1 - 0.0013 18.9 0.2 0.52 10.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KEY65241.1 - 0.0016 18.5 4.1 0.031 14.3 0.2 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KEY65241.1 - 0.0018 18.5 0.4 2.7 8.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KEY65241.1 - 0.0045 17.5 0.0 0.32 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KEY65241.1 - 0.0054 16.9 1.1 2.8 8.0 0.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA PF00004.29 KEY65241.1 - 0.0092 16.4 0.0 1.1 9.7 0.0 3.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KEY65241.1 - 0.01 15.0 0.1 0.78 8.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KEY65241.1 - 0.011 15.4 0.0 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEY65241.1 - 0.015 15.3 0.2 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KEY65241.1 - 0.017 14.6 0.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KEY65241.1 - 0.023 13.9 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KEY65241.1 - 0.035 13.8 0.4 0.47 10.1 0.1 2.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KEY65241.1 - 0.049 12.9 0.2 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KEY65241.1 - 0.05 12.9 0.4 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 KEY65241.1 - 0.087 12.5 0.2 8 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KEY65241.1 - 0.09 12.7 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KEY65241.1 - 0.17 12.1 0.3 24 5.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KEY65241.1 - 0.21 11.1 0.9 7.4 6.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3433 PF11915.8 KEY65245.1 - 2.6e-35 120.7 22.7 1.8e-29 102.0 3.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) BppU_IgG PF18667.1 KEY65245.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain WD40 PF00400.32 KEY65246.1 - 1.9e-23 82.3 2.0 3.9e-09 37.0 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEY65246.1 - 0.00013 21.1 0.0 0.034 13.1 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KEY65246.1 - 0.00014 22.1 0.0 0.11 12.8 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PUL PF08324.11 KEY65247.1 - 1.2e-65 221.5 0.2 2e-65 220.8 0.2 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KEY65247.1 - 9e-44 148.4 0.9 1.5e-43 147.6 0.9 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KEY65247.1 - 6.7e-29 99.5 8.7 4.8e-06 27.2 0.4 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65247.1 - 0.0042 17.3 0.6 20 5.6 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SRR1 PF07985.12 KEY65249.1 - 8.5e-13 48.1 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 SRR1 Glyco_hydro_17 PF00332.18 KEY65250.1 - 4.5e-10 39.6 2.5 6.9e-08 32.4 0.6 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Gly-zipper_YMGG PF13441.6 KEY65250.1 - 0.0057 16.4 7.7 0.0057 16.4 7.7 2.7 3 0 0 3 3 3 1 YMGG-like Gly-zipper Na_H_antiport_2 PF13726.6 KEY65250.1 - 0.05 13.7 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Na+-H+ antiporter family Fungal_trans_2 PF11951.8 KEY65252.1 - 2.1e-08 33.4 0.7 0.00013 21.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA_12 PF13087.6 KEY65253.1 - 2.1e-32 112.3 0.0 6.1e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEY65253.1 - 8.7e-23 81.4 2.5 1.3e-12 48.1 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEY65253.1 - 8.2e-09 35.5 0.0 8.2e-06 25.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KEY65253.1 - 3.1e-08 34.1 0.1 6.1e-07 29.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KEY65253.1 - 0.0015 18.1 0.1 0.0027 17.2 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KEY65253.1 - 0.0021 17.4 0.1 0.18 11.0 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KEY65253.1 - 0.0032 17.2 0.0 0.5 10.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KEY65253.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEY65253.1 - 0.012 15.9 0.1 0.24 11.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KEY65253.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KEY65253.1 - 0.06 13.7 0.0 0.25 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 KEY65254.1 - 3.9e-10 40.2 0.8 0.2 12.6 0.0 5.6 4 1 1 5 5 5 4 WD domain, G-beta repeat Methyltransf_PK PF05891.12 KEY65257.1 - 4.3e-73 245.4 0.0 4.9e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 KEY65257.1 - 0.00029 21.4 0.0 0.00046 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65257.1 - 0.00044 20.9 0.0 0.001 19.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEY65257.1 - 0.066 12.5 0.1 0.15 11.3 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase domain Snf7 PF03357.21 KEY65258.1 - 9.1e-06 25.4 27.0 9.2e-06 25.4 26.2 1.4 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 KEY65258.1 - 0.00012 22.0 6.0 0.00019 21.4 6.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UPF0262 PF06793.12 KEY65258.1 - 0.025 14.7 1.1 0.04 14.0 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) CEL_III_C PF18054.1 KEY65258.1 - 0.52 10.4 7.1 0.85 9.7 7.1 1.4 1 0 0 1 1 1 0 CEL-III C-terminal ASL_C PF08328.11 KEY65258.1 - 1.3 9.1 8.9 0.62 10.2 3.6 2.5 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal DSHCT PF08148.12 KEY65259.1 - 3.4e-51 173.2 0.4 7.5e-51 172.0 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KEY65259.1 - 2.4e-40 137.5 0.1 1.8e-39 134.6 0.2 2.2 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KEY65259.1 - 6.7e-29 101.7 0.0 1.2e-28 100.8 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KEY65259.1 - 7.5e-18 64.9 0.0 2.1e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY65259.1 - 1.7e-06 28.3 0.0 6.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY65259.1 - 7.2e-05 22.9 0.1 0.0003 20.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KEY65259.1 - 0.041 13.5 0.2 0.097 12.3 0.2 1.6 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Transket_pyr PF02779.24 KEY65260.1 - 4.2e-46 156.9 0.0 5.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEY65260.1 - 1.2e-36 125.4 0.0 3.3e-36 123.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Aminotran_5 PF00266.19 KEY65260.1 - 0.073 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Sterol_MT_C PF08498.10 KEY65261.1 - 5.2e-29 100.4 0.3 9.6e-29 99.5 0.3 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KEY65261.1 - 1.6e-21 76.7 0.0 3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65261.1 - 9.3e-20 71.1 0.0 2.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY65261.1 - 4.1e-18 65.6 0.0 6.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEY65261.1 - 2e-11 43.7 0.1 2.8e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KEY65261.1 - 8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY65261.1 - 1.4e-10 40.9 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEY65261.1 - 2.9e-10 40.8 0.0 7.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KEY65261.1 - 0.0005 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KEY65261.1 - 0.00059 19.6 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KEY65261.1 - 0.0013 18.2 0.0 0.0032 16.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KEY65261.1 - 0.0014 17.3 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KEY65261.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KEY65261.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 KEY65261.1 - 0.0035 17.0 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KEY65261.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 KEY65261.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KEY65261.1 - 0.042 13.8 0.1 0.097 12.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Sfi1 PF08457.10 KEY65261.1 - 0.13 10.8 0.2 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein RRM_1 PF00076.22 KEY65262.1 - 3.8e-09 36.2 0.0 6.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY65262.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEY65262.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KEY65262.1 - 0.027 14.5 0.0 0.075 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif Herpes_U5 PF05999.11 KEY65263.1 - 0.0044 15.8 0.0 0.0052 15.6 0.0 1.0 1 0 0 1 1 1 1 Herpesvirus U5-like family Complex1_LYR PF05347.15 KEY65263.1 - 0.076 13.1 0.3 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Complex 1 protein (LYR family) RAC_head PF16717.5 KEY65264.1 - 1.7e-32 112.3 4.6 1.7e-32 112.3 4.6 3.6 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 KEY65264.1 - 8.9e-20 70.6 3.2 8.9e-20 70.6 3.2 2.4 2 0 0 2 2 2 1 DnaJ domain CemA PF03040.14 KEY65264.1 - 7.5 6.4 5.2 14 5.5 5.2 1.5 1 0 0 1 1 1 0 CemA family ABC_membrane PF00664.23 KEY65265.1 - 3.4e-85 286.0 35.4 7.8e-45 153.6 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY65265.1 - 2.1e-64 216.1 0.0 8.9e-32 110.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY65265.1 - 3.4e-12 46.3 4.8 6.7e-05 22.4 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY65265.1 - 7.8e-08 32.9 0.9 0.00039 20.8 0.3 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY65265.1 - 9.5e-08 31.7 0.8 0.0041 16.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY65265.1 - 1.8e-07 31.5 0.6 0.047 14.0 0.1 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY65265.1 - 1e-06 28.7 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEY65265.1 - 1.4e-05 25.0 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KEY65265.1 - 1.6e-05 23.9 0.2 0.16 10.7 0.0 2.7 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KEY65265.1 - 0.00012 21.8 0.5 1.3 8.7 0.1 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KEY65265.1 - 0.00016 21.8 1.6 1.2 9.5 0.1 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KEY65265.1 - 0.00017 22.2 0.0 0.82 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KEY65265.1 - 0.00018 20.8 0.2 0.1 11.9 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin AAA_21 PF13304.6 KEY65265.1 - 0.00033 20.6 0.1 0.89 9.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KEY65265.1 - 0.00042 19.6 0.0 0.34 10.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KEY65265.1 - 0.00081 19.5 0.0 0.34 11.0 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KEY65265.1 - 0.0023 17.6 0.6 1.1 8.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KEY65265.1 - 0.0036 17.5 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEY65265.1 - 0.004 17.4 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEY65265.1 - 0.0042 16.6 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region APS_kinase PF01583.20 KEY65265.1 - 0.0082 16.1 0.0 0.83 9.5 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 KEY65265.1 - 0.019 15.5 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEY65265.1 - 0.02 14.9 0.1 15 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KEY65265.1 - 0.027 14.4 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KEY65265.1 - 0.036 14.1 0.0 17 5.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain Pam17 PF08566.10 KEY65265.1 - 0.039 13.8 0.1 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF87 PF01935.17 KEY65265.1 - 0.047 13.8 0.0 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 KEY65265.1 - 0.063 12.9 0.1 15 5.2 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 KEY65265.1 - 0.12 11.5 0.0 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEY65265.1 - 0.12 12.0 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEY65265.1 - 0.17 12.3 0.0 6 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Fungal_trans PF04082.18 KEY65266.1 - 5.4e-11 42.0 0.1 7.6e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 KEY65267.1 - 9.4e-06 25.8 3.0 1.5e-05 25.1 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY65267.1 - 0.00066 20.0 1.0 0.0011 19.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KEY65267.1 - 0.031 14.7 0.9 0.054 14.0 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KEY65267.1 - 0.075 13.4 0.7 0.11 12.8 0.7 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEY65267.1 - 0.084 13.8 0.3 0.16 12.9 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 KEY65267.1 - 0.19 11.8 2.9 0.34 11.1 2.9 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF1691 PF07950.11 KEY65268.1 - 1e-40 138.7 6.2 7e-34 116.8 2.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) F-box-like PF12937.7 KEY65269.1 - 7.4e-09 35.4 0.1 1.6e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY65269.1 - 1.5e-08 34.3 0.3 3e-08 33.3 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KEY65269.1 - 0.038 12.6 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 KEY65269.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box SWIRM PF04433.17 KEY65270.1 - 9.9e-14 51.4 0.2 1.8e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain adh_short_C2 PF13561.6 KEY65271.1 - 6.8e-39 133.8 0.4 4.4e-38 131.2 0.4 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY65271.1 - 8.1e-39 133.1 0.2 8.1e-39 133.1 0.2 3.1 2 0 0 2 2 2 1 short chain dehydrogenase GRIP PF01465.20 KEY65271.1 - 5.3e-13 48.6 0.3 1.4e-12 47.3 0.3 1.7 1 0 0 1 1 1 1 GRIP domain KR PF08659.10 KEY65271.1 - 5.6e-06 26.4 0.2 5.6e-06 26.4 0.2 4.7 4 1 0 4 4 4 1 KR domain Pox_A_type_inc PF04508.12 KEY65271.1 - 0.0017 18.1 0.6 0.0017 18.1 0.6 7.0 7 0 0 7 7 7 2 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KEY65271.1 - 0.0023 17.9 156.4 0.008 16.2 19.6 8.8 3 2 3 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KEY65271.1 - 0.0034 17.4 12.4 0.0034 17.4 12.4 11.9 5 3 5 11 11 11 1 Designed helical repeat protein 10 domain DivIC PF04977.15 KEY65271.1 - 0.0037 17.0 0.6 0.0037 17.0 0.6 13.4 11 3 3 15 15 15 3 Septum formation initiator HAP1_N PF04849.13 KEY65271.1 - 0.0061 15.8 2.1 0.0061 15.8 2.1 7.6 3 2 3 7 7 6 1 HAP1 N-terminal conserved region ADH_zinc_N PF00107.26 KEY65271.1 - 0.0087 16.0 0.1 0.027 14.5 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KEY65271.1 - 0.0092 16.1 0.0 0.081 13.0 0.0 2.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KEY65271.1 - 0.12 12.9 1.2 0.57 10.8 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zinc_ribbon_10 PF10058.9 KEY65272.1 - 2.6e-17 62.3 0.0 4.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 KEY65272.1 - 0.045 14.1 0.5 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkr1 PF08636.10 KEY65272.1 - 0.19 11.9 0.2 0.34 11.1 0.2 1.3 1 0 0 1 1 1 0 ER protein Pkr1 zf-RanBP PF00641.18 KEY65272.1 - 0.57 9.5 2.2 1.2 8.5 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pkinase PF00069.25 KEY65273.1 - 1.8e-40 139.0 0.1 1.7e-22 80.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65273.1 - 2.7e-14 53.1 0.1 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.11 KEY65275.1 - 2.2e-10 40.4 0.0 4.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.9 KEY65276.1 - 7.4e-35 119.6 1.3 1.1e-34 119.1 1.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF550 PF04447.12 KEY65276.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Pericardin_rpt PF07054.11 KEY65276.1 - 0.24 11.6 1.8 0.44 10.7 1.8 1.4 1 0 0 1 1 1 0 Pericardin like repeat Fungal_trans PF04082.18 KEY65277.1 - 8.4e-22 77.5 2.8 2.5e-21 75.9 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65277.1 - 1.5e-07 31.4 12.1 2.7e-07 30.6 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1744 PF08490.12 KEY65277.1 - 0.12 10.9 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) SCAI PF12070.8 KEY65278.1 - 0.0096 14.8 2.7 0.013 14.4 2.7 1.1 1 0 0 1 1 1 1 Protein SCAI EIF4E-T PF10477.9 KEY65278.1 - 1.3 7.8 12.3 1.9 7.2 12.3 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4298 PF14131.6 KEY65278.1 - 1.3 9.0 7.0 2.5 8.1 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Aa_trans PF01490.18 KEY65279.1 - 6.4e-45 153.6 32.4 8.4e-45 153.2 32.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NTP_transf_9 PF04248.12 KEY65280.1 - 1.5e-33 114.5 0.4 2e-33 114.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) bZIP_2 PF07716.15 KEY65281.1 - 2.2e-06 27.6 19.2 3.9e-06 26.9 19.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KEY65281.1 - 0.00019 21.5 15.6 0.00033 20.7 15.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KEY65281.1 - 0.026 15.0 11.3 0.048 14.2 11.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.11 KEY65281.1 - 0.78 9.8 5.4 1.1 9.4 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Swi3 PF07962.12 KEY65282.1 - 9.7e-31 105.6 0.2 1.3e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Cwf_Cwc_15 PF04889.12 KEY65282.1 - 7.5 6.2 11.7 42 3.8 11.7 2.0 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NADH-u_ox-rdase PF10785.9 KEY65283.1 - 8.7e-29 100.0 0.1 1.4e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KEY65283.1 - 1.3e-24 86.0 0.0 1.8e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Response_reg PF00072.24 KEY65284.1 - 2.4e-18 66.3 0.0 6.2e-18 65.0 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KEY65284.1 - 1.3e-13 51.4 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEY65284.1 - 5.3e-10 39.2 0.0 1.5e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KEY65284.1 - 8e-05 22.5 0.0 0.00023 21.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.18 KEY65285.1 - 8.4e-06 25.3 6.6 3.1e-05 23.5 6.3 1.8 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein HIM1 PF08732.10 KEY65285.1 - 0.0039 16.7 0.1 2.7 7.5 0.1 2.3 2 0 0 2 2 2 2 HIM1 Golgin_A5 PF09787.9 KEY65285.1 - 0.042 13.3 1.1 0.061 12.8 1.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DNA_repr_REX1B PF14966.6 KEY65285.1 - 0.051 14.3 0.2 0.28 11.9 0.0 2.2 1 1 1 2 2 2 0 DNA repair REX1-B TRPM_tetra PF16519.5 KEY65285.1 - 0.51 10.5 2.2 16 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetramerisation domain of TRPM Ribonuc_L-PSP PF01042.21 KEY65286.1 - 8.1e-29 100.1 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Hydrophobin_2 PF06766.11 KEY65287.1 - 1e-24 86.2 8.7 1.6e-24 85.6 8.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Xan_ur_permease PF00860.20 KEY65289.1 - 4.9e-25 88.1 28.8 2.8e-23 82.3 25.4 2.8 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.20 KEY65289.1 - 5.9e-05 22.0 2.6 5.9e-05 22.0 2.6 3.1 2 1 1 3 3 3 2 Sulfate permease family DUF3328 PF11807.8 KEY65290.1 - 1.2e-45 156.0 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DIOX_N PF14226.6 KEY65291.1 - 0.00013 22.7 0.0 0.00039 21.2 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY65291.1 - 0.00089 19.7 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_5 PF13854.6 KEY65293.1 - 7.8e-08 32.1 0.3 7.8e-08 32.1 0.3 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 KEY65293.1 - 4.4e-07 29.8 17.7 0.0014 18.6 0.4 6.1 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY65293.1 - 1.7e-06 28.1 10.1 0.011 16.1 0.0 4.7 6 1 1 7 7 7 2 Kelch motif Kelch_1 PF01344.25 KEY65293.1 - 0.00011 21.7 9.3 0.088 12.4 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KEY65293.1 - 0.00043 20.5 7.3 0.13 12.6 0.1 5.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KEY65293.1 - 0.0013 18.7 9.7 3.5 7.8 0.1 6.3 6 1 0 6 6 6 1 Kelch motif Adeno_E3_CR2 PF02439.15 KEY65293.1 - 0.098 12.4 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FMN_dh PF01070.18 KEY65294.1 - 7.3e-79 265.3 0.0 6.3e-48 163.6 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KEY65294.1 - 0.0064 15.5 0.0 0.013 14.5 0.0 1.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEY65294.1 - 0.072 12.4 0.1 6.2 6.1 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KEY65294.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Peptidase_M28 PF04389.17 KEY65294.1 - 0.11 12.2 0.1 0.41 10.3 0.2 1.8 1 1 1 2 2 2 0 Peptidase family M28 ADH_zinc_N_2 PF13602.6 KEY65295.1 - 3.1e-15 57.4 0.0 5.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY65295.1 - 1.1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY65295.1 - 5e-06 26.5 0.1 8.9e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KEY65295.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 KEY65295.1 - 0.049 13.1 0.1 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Peptidase_M49 PF03571.15 KEY65295.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M49 TPR_10 PF13374.6 KEY65296.1 - 6.5e-32 108.5 1.0 5.6e-10 38.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65296.1 - 1.1e-26 92.9 0.6 7.2e-13 48.6 0.1 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 KEY65296.1 - 2.9e-05 24.2 0.3 0.17 12.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KEY65296.1 - 0.00023 21.4 0.2 0.16 12.3 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65296.1 - 0.00037 20.3 0.4 2.4 8.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Pterin_4a PF01329.19 KEY65296.1 - 0.031 14.4 0.4 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase LRR_8 PF13855.6 KEY65296.1 - 0.19 11.6 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat Acyl-CoA_dh_M PF02770.19 KEY65298.1 - 3.3e-05 24.0 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain FtsJ PF01728.19 KEY65299.1 - 1.5e-15 57.8 0.0 2.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase EcKinase PF02958.20 KEY65300.1 - 5.8e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KEY65300.1 - 1.3e-10 41.6 0.1 1.3e-10 41.6 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY65300.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.33 KEY65301.1 - 9.2e-08 31.8 0.4 2.4e-07 30.5 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY65301.1 - 0.00022 21.1 0.2 0.00054 19.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like Thymidylat_synt PF00303.19 KEY65302.1 - 4.8e-109 363.6 0.0 5.5e-109 363.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase UPF0113_N PF17833.1 KEY65303.1 - 6.8e-24 84.2 0.0 9.2e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KEY65303.1 - 1.8e-22 79.4 0.0 2.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KEY65303.1 - 0.0029 17.5 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain Ctr PF04145.15 KEY65304.1 - 2.8e-39 135.1 0.8 3.4e-39 134.8 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 KEY65304.1 - 0.65 8.2 5.5 1 7.5 5.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pkinase PF00069.25 KEY65305.1 - 5.9e-35 120.9 0.0 8.1e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65305.1 - 1.6e-19 70.2 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEY65305.1 - 0.0027 17.1 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PD40 PF07676.12 KEY65305.1 - 0.0029 17.5 0.1 2.4 8.2 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat RIO1 PF01163.22 KEY65305.1 - 0.029 13.9 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family AA_permease_2 PF13520.6 KEY65306.1 - 1.7e-59 201.8 38.4 2e-59 201.5 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY65306.1 - 3.4e-23 82.0 39.2 5.4e-22 78.0 39.2 2.2 1 1 0 1 1 1 1 Amino acid permease SNF PF00209.18 KEY65307.1 - 7.3e-95 318.6 39.8 2.2e-59 201.6 17.7 2.6 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family Glyco_hydro_47 PF01532.20 KEY65311.1 - 1.3e-177 591.3 0.0 1.5e-177 591.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KEY65311.1 - 0.052 12.0 0.1 8 4.8 0.1 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 SGT1 PF07093.11 KEY65311.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein Alpha-amylase PF00128.24 KEY65312.1 - 4.3e-57 194.2 0.1 2.7e-55 188.3 0.1 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KEY65312.1 - 0.0054 15.0 0.3 0.045 11.9 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolase family 70 GHL6 PF14871.6 KEY65312.1 - 0.042 14.0 0.2 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF1966 PF09260.11 KEY65312.1 - 0.058 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) p450 PF00067.22 KEY65315.1 - 4.4e-48 164.2 0.0 5.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 N2227 PF07942.12 KEY65316.1 - 1.6e-61 207.9 0.0 2.5e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Transferase PF02458.15 KEY65316.1 - 6e-05 21.9 0.0 0.00018 20.3 0.0 1.9 1 1 0 1 1 1 1 Transferase family Methyltransf_23 PF13489.6 KEY65316.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY65316.1 - 0.0065 17.2 0.0 0.032 15.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65316.1 - 0.058 14.0 0.0 0.34 11.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KEY65316.1 - 0.18 11.6 0.0 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase Sugar_tr PF00083.24 KEY65317.1 - 1.6e-115 386.6 24.9 1.8e-115 386.4 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY65317.1 - 4.4e-26 91.6 41.1 2.6e-23 82.6 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_9 PF13371.6 KEY65317.1 - 0.0088 16.2 0.3 0.019 15.1 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat MFS_1 PF07690.16 KEY65319.1 - 2.2e-21 76.2 45.0 2.3e-21 76.1 42.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEY65320.1 - 1.6e-25 89.8 53.0 4e-17 62.2 13.2 3.6 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY65320.1 - 3.1e-10 39.5 12.4 2.4e-09 36.6 2.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter C5HCH PF17982.1 KEY65321.1 - 2.1 8.6 7.6 5.8 7.2 7.6 1.8 1 0 0 1 1 1 0 NSD Cys-His rich domain Glyco_hydro_61 PF03443.14 KEY65322.1 - 1.6e-24 87.0 0.0 2.2e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_MOT1 PF16983.5 KEY65323.1 - 0.38 11.2 6.3 4.2 7.8 0.0 3.2 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily F-box-like PF12937.7 KEY65324.1 - 0.00014 21.7 0.0 0.003 17.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY65324.1 - 0.014 15.3 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 F-box domain GMC_oxred_N PF00732.19 KEY65326.1 - 3.1e-37 128.6 0.1 6.7e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY65326.1 - 7.3e-26 91.4 0.0 1.1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FrhB_FdhB_N PF04422.13 KEY65326.1 - 0.12 12.6 0.1 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term p450 PF00067.22 KEY65327.1 - 5.3e-54 183.7 0.0 7e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEY65328.1 - 0.012 15.7 9.3 0.013 15.6 8.0 1.7 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KEY65329.1 - 1.3e-08 34.7 0.0 6e-08 32.5 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY65329.1 - 1.8e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 KEY65330.1 - 1.7e-72 244.0 0.4 3.5e-72 243.0 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY65330.1 - 6.5e-33 114.6 0.3 5.9e-31 108.2 0.2 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY65330.1 - 2.2e-31 108.3 0.0 5.1e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KEY65330.1 - 1.7e-27 95.1 0.0 4.8e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 KEY65330.1 - 9.1e-25 87.3 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KEY65330.1 - 4.3e-15 56.3 0.0 1.1e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEY65330.1 - 2e-14 53.7 0.4 4.9e-14 52.4 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KEY65330.1 - 7.7e-11 42.6 0.0 4.6e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY65330.1 - 1e-10 41.7 0.0 3.6e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain SAT PF16073.5 KEY65330.1 - 1.1e-09 38.4 4.7 3e-06 27.2 0.4 3.1 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_11 PF08241.12 KEY65330.1 - 2.5e-08 34.4 0.0 1.4e-07 32.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY65330.1 - 3.3e-08 33.5 0.0 2.5e-07 30.6 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY65330.1 - 4e-07 30.5 0.1 3.4e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY65330.1 - 6.6e-06 25.7 0.7 7.6e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.21 KEY65330.1 - 3.7e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 KEY65330.1 - 0.00025 20.4 0.0 0.00055 19.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KEY65330.1 - 0.002 17.8 0.1 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KEY65330.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 KEY65330.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DXP_reductoisom PF02670.16 KEY65330.1 - 0.057 14.1 0.0 0.24 12.1 0.0 2.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 KEY65330.1 - 0.093 11.8 0.0 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.26 KEY65331.1 - 1.6e-75 254.0 0.0 1.3e-74 251.0 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KEY65331.1 - 4.3e-75 252.9 0.0 8.2e-75 252.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KEY65331.1 - 3.7e-52 177.5 0.0 5.8e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KEY65331.1 - 2.1e-49 167.9 0.1 2e-47 161.4 0.0 3.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KEY65331.1 - 4.8e-47 161.0 0.1 9e-47 160.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY65331.1 - 4.7e-42 144.2 0.0 9.1e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 KEY65331.1 - 1.9e-32 112.4 0.0 5.1e-32 111.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KEY65331.1 - 1.1e-28 99.6 0.0 2.9e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEY65331.1 - 2.5e-19 69.4 0.7 1.7e-08 34.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEY65331.1 - 6.6e-19 68.5 0.0 3.1e-18 66.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 KEY65331.1 - 7.4e-18 64.9 0.0 3.4e-14 52.9 0.0 3.2 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KEY65331.1 - 7.2e-14 52.2 0.0 8.7e-13 48.7 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KEY65331.1 - 6.1e-13 49.3 0.0 4.1e-12 46.7 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65331.1 - 8.9e-12 45.5 0.0 7.9e-11 42.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY65331.1 - 1.3e-10 41.3 0.0 5.6e-10 39.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY65331.1 - 1.8e-09 37.7 0.0 5.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEY65331.1 - 2.9e-09 36.7 0.0 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KEY65331.1 - 5.5e-08 32.1 0.0 1.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY65331.1 - 0.00012 21.6 0.0 0.17 11.2 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 KEY65331.1 - 0.00027 20.4 0.2 0.00066 19.1 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KEY65331.1 - 0.0023 17.3 0.0 0.0058 16.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEY65331.1 - 0.0025 17.6 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase adh_short_C2 PF13561.6 KEY65331.1 - 0.011 15.4 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_24 PF13578.6 KEY65331.1 - 0.027 15.5 0.0 0.16 13.0 0.0 2.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding_C PF13193.6 KEY65331.1 - 0.042 14.8 0.0 0.15 13.0 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 KEY65331.1 - 0.17 11.8 0.4 0.59 10.0 0.4 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.11 KEY65332.1 - 8.2e-14 52.5 0.2 1.1e-13 52.2 0.2 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.16 KEY65333.1 - 7.1e-40 137.0 55.0 1.5e-39 135.9 52.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY65333.1 - 3.7e-18 65.3 20.4 4.5e-18 65.0 20.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEY65333.1 - 4.8e-10 38.9 15.0 4.8e-10 38.9 15.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_holin_2_1 PF04971.12 KEY65333.1 - 0.015 15.3 0.3 0.068 13.2 0.3 2.2 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF3522 PF12036.8 KEY65333.1 - 0.028 14.7 0.8 0.64 10.3 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) ABM PF03992.16 KEY65335.1 - 0.12 12.5 0.0 0.45 10.7 0.0 2.0 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Glyco_hydro_16 PF00722.21 KEY65336.1 - 1.5e-20 73.4 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEY65336.1 - 2.3e-08 32.9 1.7 0.0025 16.3 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_61 PF03443.14 KEY65337.1 - 4.7e-63 212.8 0.2 7e-63 212.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2052 PF09747.9 KEY65337.1 - 6.5e-19 68.8 9.0 1.4e-12 48.2 8.7 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Glyco_hydro_43 PF04616.14 KEY65339.1 - 4.6e-30 104.9 0.6 1.2e-28 100.3 0.6 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 KEY65339.1 - 0.46 9.3 2.7 31 3.2 0.0 3.4 3 1 1 4 4 4 0 Levansucrase/Invertase Tom6 PF17112.5 KEY65340.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Response_reg PF00072.24 KEY65342.1 - 3.9e-23 81.7 0.0 1.5e-16 60.6 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain DUF2000 PF09391.10 KEY65342.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Bot1p PF12298.8 KEY65343.1 - 4.5e-49 166.9 0.5 8e-49 166.1 0.4 1.5 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.6 KEY65344.1 - 3e-57 194.2 0.0 3.4e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEY65344.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MARVEL PF01284.23 KEY65345.1 - 0.0063 16.5 5.7 0.16 12.0 3.0 2.1 2 0 0 2 2 2 2 Membrane-associating domain Stathmin PF00836.19 KEY65346.1 - 0.05 13.6 2.3 0.087 12.8 2.3 1.3 1 0 0 1 1 1 0 Stathmin family DUF2439 PF10382.9 KEY65347.1 - 6.7e-24 84.0 0.0 1.2e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.18 KEY65348.1 - 0.29 11.3 7.8 0.51 10.5 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 KEY65350.1 - 2.6e-20 72.2 0.0 1.2e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY65350.1 - 1e-16 61.0 0.0 5.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KEY65350.1 - 0.0034 17.5 3.2 0.23 11.5 3.2 3.0 1 1 0 1 1 1 1 Bd3614-like deaminase Lipase_3 PF01764.25 KEY65351.1 - 4.1e-17 62.4 0.0 9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY65351.1 - 0.032 14.8 0.1 0.079 13.5 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY65351.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TauD PF02668.16 KEY65352.1 - 7.1e-33 114.5 0.1 9.5e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family tRNA-synt_1c PF00749.21 KEY65353.1 - 4.3e-97 324.8 0.0 6.8e-97 324.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEY65353.1 - 2.5e-28 99.1 0.0 5.7e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Abhydrolase_6 PF12697.7 KEY65354.1 - 3.4e-09 37.6 0.1 4.1e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 KEY65355.1 - 5.7e-37 127.5 0.0 1.9e-36 125.8 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Citrate_synt PF00285.21 KEY65356.1 - 9.9e-122 406.5 0.0 1.2e-121 406.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain NmrA PF05368.13 KEY65357.1 - 0.0047 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family p450 PF00067.22 KEY65358.1 - 3.2e-44 151.4 0.1 2.5e-29 102.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 GST_N_3 PF13417.6 KEY65359.1 - 5.7e-11 42.7 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY65359.1 - 6.7e-09 35.9 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY65359.1 - 2.3e-06 27.5 0.5 6e-06 26.2 0.5 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEY65359.1 - 4.5e-05 23.7 0.0 0.00011 22.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY65359.1 - 0.00027 21.1 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY65359.1 - 0.018 15.2 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KEY65361.1 - 2.7e-42 144.5 0.5 3.9e-42 144.0 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEY65361.1 - 5.6e-21 74.5 0.1 1.1e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEY65361.1 - 7.7e-21 74.9 0.0 1.6e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KEY65361.1 - 3.3e-19 68.8 0.3 6.9e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KEY65361.1 - 5.9e-08 33.1 0.0 9.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_N PF00752.17 KEY65362.1 - 2.9e-31 107.9 1.6 3e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KEY65362.1 - 7.7e-31 106.3 1.2 1.3e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KEY65362.1 - 1.8e-06 28.4 0.3 1.4e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KEY65362.1 - 0.088 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain WSC PF01822.19 KEY65364.1 - 4.1e-10 39.7 6.0 1e-09 38.5 6.0 1.6 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KEY65364.1 - 0.0002 20.7 0.6 0.00041 19.7 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KEY65364.1 - 0.014 15.5 0.1 0.087 12.9 0.0 2.0 2 0 0 2 2 2 0 Podoplanin Gram_pos_anchor PF00746.21 KEY65364.1 - 0.068 13.1 0.6 0.14 12.1 0.6 1.6 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Nitrate_red_gam PF02665.14 KEY65364.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Asp PF00026.23 KEY65365.1 - 8.9e-109 363.7 0.0 1.1e-108 363.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY65365.1 - 2.3e-15 57.3 5.9 7.6e-14 52.3 2.7 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY65365.1 - 3.6e-05 24.3 0.0 0.5 11.0 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KEY65365.1 - 0.00018 21.3 0.0 0.0036 17.1 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KEY65365.1 - 0.0019 18.7 0.0 2.2 8.9 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease BDHCT_assoc PF16204.5 KEY65365.1 - 0.019 14.7 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein ThylakoidFormat PF11264.8 KEY65366.1 - 0.076 12.7 0.6 0.17 11.5 0.6 1.5 1 0 0 1 1 1 0 Thylakoid formation protein DUF155 PF02582.14 KEY65367.1 - 4.2e-48 163.7 0.0 5.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 KEY65367.1 - 0.049 13.2 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin CRAL_TRIO PF00650.20 KEY65368.1 - 1.7e-34 118.9 0.0 2.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY65368.1 - 3e-08 33.7 0.1 7.5e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KEY65368.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Mis14 PF08641.12 KEY65369.1 - 2.8e-19 69.8 5.2 3.3e-19 69.5 0.9 2.3 2 0 0 2 2 2 1 Kinetochore protein Mis14 like LON_substr_bdg PF02190.16 KEY65369.1 - 0.0038 17.1 0.1 0.0062 16.4 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Rab5-bind PF09311.11 KEY65369.1 - 0.017 14.6 0.8 0.03 13.7 0.8 1.4 1 0 0 1 1 1 0 Rabaptin-like protein MAP65_ASE1 PF03999.12 KEY65370.1 - 4.1 6.0 5.3 4.4 5.9 5.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) AAA PF00004.29 KEY65371.1 - 2.9e-45 153.9 0.5 8.1e-45 152.5 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEY65371.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KEY65371.1 - 6.8e-09 35.8 0.3 2.2e-08 34.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEY65371.1 - 4.9e-08 33.3 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEY65371.1 - 1.6e-07 31.8 0.3 3.7e-05 24.2 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KEY65371.1 - 3.4e-06 26.4 0.0 6.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEY65371.1 - 4.4e-05 23.8 1.2 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KEY65371.1 - 0.00024 20.9 0.0 0.00069 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KEY65371.1 - 0.00037 20.2 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 KEY65371.1 - 0.00055 20.5 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEY65371.1 - 0.00072 19.1 0.1 0.0026 17.3 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KEY65371.1 - 0.00079 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEY65371.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KEY65371.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KEY65371.1 - 0.0019 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KEY65371.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KEY65371.1 - 0.0032 17.4 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KEY65371.1 - 0.005 16.8 0.3 0.11 12.4 0.0 2.9 4 0 0 4 4 3 1 NACHT domain AAA_30 PF13604.6 KEY65371.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KEY65371.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEY65371.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEY65371.1 - 0.0095 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KEY65371.1 - 0.01 15.3 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KEY65371.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEY65371.1 - 0.018 14.8 0.3 0.055 13.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KEY65371.1 - 0.026 13.9 0.1 0.56 9.5 0.0 2.4 2 0 0 2 2 2 0 KaiC Viral_Hsp90 PF03225.14 KEY65371.1 - 0.029 12.9 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AFG1_ATPase PF03969.16 KEY65371.1 - 0.039 12.8 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 KEY65371.1 - 0.043 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KEY65371.1 - 0.044 13.7 1.0 0.33 10.8 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KEY65371.1 - 0.056 13.2 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KEY65371.1 - 0.078 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KEY65371.1 - 0.084 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KEY65371.1 - 0.088 12.4 1.2 0.27 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KEY65371.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEY65371.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KEY65371.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KEY65371.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.8 KEY65372.1 - 4.9e-59 199.3 0.0 1.1e-58 198.2 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 KEY65374.1 - 1.8e-28 99.6 0.0 5.2e-14 52.8 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY65374.1 - 2.9e-12 47.0 7.0 0.046 14.0 0.1 6.4 4 2 0 4 4 4 3 AAA domain AAA_5 PF07728.14 KEY65374.1 - 8.8e-11 42.0 0.2 0.025 14.6 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_6 PF17866.1 KEY65374.1 - 4.3e-10 39.6 0.1 1.6e-08 34.6 0.0 3.3 3 0 0 3 3 3 1 AAA lid domain AAA_30 PF13604.6 KEY65374.1 - 6.5e-08 32.5 0.5 0.036 13.8 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEY65374.1 - 2.5e-07 31.3 5.4 1.2 9.4 0.1 5.7 4 2 0 6 6 6 2 AAA ATPase domain RNA_helicase PF00910.22 KEY65374.1 - 1.3e-06 28.7 0.0 1.9 8.9 0.0 3.7 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 KEY65374.1 - 1.9e-06 27.4 0.1 0.4 10.0 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEY65374.1 - 2.3e-06 27.8 0.8 0.5 10.5 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KEY65374.1 - 4.3e-06 27.3 1.3 1.1 9.8 0.1 4.2 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 KEY65374.1 - 5.2e-06 26.8 2.2 0.64 10.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KEY65374.1 - 1.2e-05 25.1 0.1 0.15 11.8 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEY65374.1 - 1.4e-05 24.9 0.4 0.69 9.6 0.1 4.1 3 2 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEY65374.1 - 1.4e-05 24.9 3.9 1.8 8.3 0.1 4.2 4 0 0 4 4 4 3 AAA domain AAA_19 PF13245.6 KEY65374.1 - 4.9e-05 23.7 0.3 2.6 8.4 0.1 4.3 3 1 1 4 4 4 1 AAA domain Sigma54_activat PF00158.26 KEY65374.1 - 0.0002 21.1 1.0 0.36 10.5 0.0 4.2 4 1 0 4 4 4 1 Sigma-54 interaction domain AAA_11 PF13086.6 KEY65374.1 - 0.00043 20.2 0.1 0.97 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KEY65374.1 - 0.00082 18.9 0.3 5.4 6.5 0.0 3.6 3 0 0 3 3 3 0 P-loop containing dynein motor region Torsin PF06309.11 KEY65374.1 - 0.0012 19.0 0.0 11 6.1 0.0 3.8 4 0 0 4 4 3 0 Torsin Viral_helicase1 PF01443.18 KEY65374.1 - 0.0013 18.5 0.1 7.4 6.2 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KEY65374.1 - 0.0021 18.6 0.6 2.5 8.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Sigma54_activ_2 PF14532.6 KEY65374.1 - 0.0023 18.1 0.0 3.1 7.9 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.6 KEY65374.1 - 0.0026 18.2 0.6 3.9 7.9 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KEY65374.1 - 0.0076 16.0 0.0 2.8 7.8 0.0 3.5 4 0 0 4 4 3 1 P-loop containing region of AAA domain GTP_EFTU_D4 PF14578.6 KEY65374.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 VirE PF05272.11 KEY65374.1 - 0.027 14.2 2.5 0.12 12.1 0.0 2.9 4 0 0 4 4 3 0 Virulence-associated protein E Cytidylate_kin PF02224.18 KEY65374.1 - 0.038 13.7 0.4 36 4.0 0.0 3.6 3 0 0 3 3 3 0 Cytidylate kinase ResIII PF04851.15 KEY65374.1 - 0.062 13.3 0.3 44 4.0 0.0 4.3 4 1 0 5 5 5 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KEY65374.1 - 0.071 12.7 0.2 3 7.4 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEY65374.1 - 0.076 12.6 0.9 11 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KEY65374.1 - 0.095 12.4 0.4 32 4.2 0.1 3.2 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 KEY65374.1 - 0.14 11.6 2.7 21 4.5 0.0 3.5 4 0 0 4 4 3 0 PhoH-like protein AAA_32 PF13654.6 KEY65374.1 - 0.16 10.7 0.4 0.76 8.5 0.0 2.3 4 0 0 4 4 4 0 AAA domain DUF1510 PF07423.11 KEY65374.1 - 0.17 12.0 0.0 0.64 10.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) NTPase_1 PF03266.15 KEY65374.1 - 1.3 9.0 3.5 21 5.0 0.1 3.2 3 0 0 3 3 3 0 NTPase DNA_methylase PF00145.17 KEY65375.1 - 9.2e-29 100.8 0.0 1.7e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KEY65375.1 - 0.0016 18.3 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 BAH domain Drc1-Sld2 PF11719.8 KEY65376.1 - 6.1e-96 322.7 15.0 6.9e-96 322.5 15.0 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DUF3235 PF11574.8 KEY65376.1 - 2.9 8.8 4.8 26 5.8 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) zf-RING_2 PF13639.6 KEY65377.1 - 2.9e-08 33.9 11.3 5.4e-08 33.0 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEY65377.1 - 1.5e-05 24.8 7.7 2.3e-05 24.2 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY65377.1 - 1.8e-05 24.5 6.7 3.5e-05 23.6 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY65377.1 - 0.0001 22.1 9.8 0.0001 22.1 9.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEY65377.1 - 0.00015 22.0 8.3 0.00044 20.5 8.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain DUF2863 PF11062.8 KEY65377.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) zf-RING_11 PF17123.5 KEY65377.1 - 0.29 10.9 4.4 0.63 9.8 4.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger DASH_Spc34 PF08657.10 KEY65378.1 - 7.7e-54 183.2 2.1 1.3e-28 100.5 0.8 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 OmpH PF03938.14 KEY65378.1 - 0.62 10.4 6.5 0.93 9.8 6.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2407_C PF13373.6 KEY65378.1 - 3.8 7.7 6.4 7.1 6.8 6.4 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rpn3_C PF08375.11 KEY65380.1 - 1.6e-25 89.3 1.7 5.1e-25 87.7 1.7 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KEY65380.1 - 1.7e-19 70.3 0.0 4.7e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain TFIID_20kDa PF03847.13 KEY65380.1 - 5.5e-17 62.0 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TPR_2 PF07719.17 KEY65380.1 - 0.016 15.3 0.8 0.063 13.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 KEY65381.1 - 4.2e-12 45.1 0.4 0.37 11.0 0.0 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KEY65381.1 - 0.036 14.6 0.1 3.8e+02 2.3 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 KEY65381.1 - 0.046 14.2 0.0 10 6.7 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) MOZ_SAS PF01853.18 KEY65382.1 - 1.3e-55 187.9 0.0 2e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEY65382.1 - 1.1e-07 31.4 0.6 0.00099 18.7 0.0 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain ATP-synt_C PF00137.21 KEY65383.1 - 7e-11 42.3 12.2 1.8e-10 41.0 12.2 1.7 1 0 0 1 1 1 1 ATP synthase subunit C DNA_pol_A_exo1 PF01612.20 KEY65384.1 - 2.5e-38 131.5 0.1 5e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KEY65384.1 - 1.7e-26 92.7 0.5 1.7e-26 92.7 0.5 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KEY65384.1 - 6.3e-10 38.9 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain NAM-associated PF14303.6 KEY65384.1 - 5.4 7.7 20.4 13 6.5 20.4 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Glyco_transf_20 PF00982.21 KEY65385.1 - 1.2e-196 654.1 0.0 1.4e-196 653.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KEY65385.1 - 0.033 13.9 0.1 0.086 12.5 0.1 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KEY65385.1 - 0.42 10.1 1.3 7.9 6.0 0.0 2.9 3 1 0 3 3 3 0 Glycosyl transferases group 1 VID27 PF08553.10 KEY65386.1 - 2.8e-191 635.2 0.2 3.7e-191 634.8 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KEY65386.1 - 1e-74 250.1 0.3 1e-74 250.1 0.3 3.3 2 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KEY65386.1 - 1.7e-41 140.9 1.1 4.1e-41 139.7 0.6 1.9 2 0 0 2 2 2 1 VID27 PH-like domain Peptidase_S10 PF00450.22 KEY65386.1 - 0.0034 16.8 0.2 0.0053 16.2 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DNA_pol_phi PF04931.13 KEY65386.1 - 1 7.4 6.2 1.6 6.8 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Prenylcys_lyase PF07156.14 KEY65387.1 - 1.9e-88 297.0 0.0 2.6e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KEY65387.1 - 5.3e-13 49.0 0.1 1.2e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEY65387.1 - 3.3e-10 39.8 0.0 5.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEY65387.1 - 1.3e-07 31.5 0.2 2.9e-06 27.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY65387.1 - 0.00021 20.6 0.2 0.0034 16.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY65387.1 - 0.00026 21.0 0.0 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEY65387.1 - 0.0068 15.5 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEY65387.1 - 0.03 13.6 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KEY65387.1 - 0.1 11.7 0.3 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KEY65387.1 - 0.12 13.0 0.1 2.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEY65387.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FRQ PF09421.10 KEY65388.1 - 0 1386.5 53.7 0 1385.3 53.7 1.5 1 1 0 1 1 1 1 Frequency clock protein FlxA PF14282.6 KEY65388.1 - 1.6 8.7 6.3 0.16 12.0 0.4 2.4 2 0 0 2 2 2 0 FlxA-like protein iPGM_N PF06415.13 KEY65389.1 - 8.6e-76 254.2 0.0 1.2e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KEY65389.1 - 3.8e-68 229.5 0.0 4.4e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KEY65389.1 - 6.7e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEY65389.1 - 0.00014 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1877 PF08974.10 KEY65389.1 - 0.019 15.1 0.0 0.049 13.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) Med9 PF07544.13 KEY65390.1 - 2.1e-18 66.2 0.1 4.8e-18 65.0 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Spc29 PF17082.5 KEY65390.1 - 0.0029 17.5 0.1 0.0037 17.1 0.1 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 Phage_GP20 PF06810.11 KEY65390.1 - 0.024 14.5 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Med21 PF11221.8 KEY65390.1 - 0.029 14.6 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF4349 PF14257.6 KEY65390.1 - 0.037 13.5 0.1 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TBCC PF07986.12 KEY65391.1 - 6.3e-30 103.4 0.0 1e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KEY65391.1 - 2e-09 37.9 0.1 3.7e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Gpi1 PF05024.15 KEY65393.1 - 3.2e-78 262.1 7.0 3.2e-78 262.1 7.0 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 KEY65393.1 - 1.2e-25 89.6 3.5 2.3e-25 88.6 3.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 KEY65393.1 - 0.00038 19.9 1.1 0.0084 15.5 0.6 2.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) UCR_hinge PF02320.16 KEY65393.1 - 0.029 14.6 0.3 0.075 13.2 0.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 KEY65393.1 - 0.031 14.6 2.4 0.035 14.5 0.5 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Aldose_epim PF01263.20 KEY65395.1 - 2.2e-60 204.5 0.1 2.7e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.8 KEY65397.1 - 9.4e-32 108.8 0.0 1.5e-31 108.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) THB PF18362.1 KEY65397.1 - 0.0076 15.8 0.5 2.7 7.7 0.2 2.6 3 0 0 3 3 3 2 Tri-helix bundle domain SARAF PF06682.12 KEY65397.1 - 0.0083 15.8 0.2 0.013 15.1 0.2 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis U79_P34 PF03064.16 KEY65397.1 - 0.27 10.5 1.9 0.38 10.1 1.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1744 PF08490.12 KEY65398.1 - 1.2e-150 501.6 0.0 1.7e-150 501.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KEY65398.1 - 2e-78 263.9 0.5 1.7e-77 260.8 0.2 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KEY65398.1 - 1.8e-16 59.9 0.3 7.3e-14 51.3 0.2 3.0 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KEY65398.1 - 1.2e-09 38.2 0.1 3.1e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KEY65398.1 - 9.7e-07 28.9 0.0 4e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily HET PF06985.11 KEY65399.1 - 1.6e-26 93.4 0.2 3.3e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clathrin PF00637.20 KEY65401.1 - 2e-20 73.1 5.6 3.3e-20 72.4 0.7 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 KEY65401.1 - 0.00021 21.2 0.5 0.00053 19.9 0.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.9 KEY65401.1 - 0.0017 18.6 0.3 0.0088 16.3 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 KEY65401.1 - 0.11 13.4 1.1 55 4.9 0.0 4.4 5 0 0 5 5 4 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 KEY65401.1 - 0.22 11.9 2.9 0.25 11.7 0.4 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KEY65401.1 - 0.45 10.3 3.7 0.95 9.3 3.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger SDA1 PF05285.12 KEY65401.1 - 0.82 9.0 14.7 0.014 14.9 7.4 1.7 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.13 KEY65401.1 - 0.9 7.6 21.8 1.6 6.8 21.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPL5 PF18168.1 KEY65401.1 - 1.2 8.3 3.9 2.5 7.3 3.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 zf-rbx1 PF12678.7 KEY65401.1 - 1.6 9.0 4.1 0.68 10.3 0.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain BUD22 PF09073.10 KEY65401.1 - 1.7 7.9 17.9 0.084 12.2 11.3 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KEY65401.1 - 5 5.2 19.1 8.9 4.4 19.1 1.3 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.11 KEY65401.1 - 6.9 5.4 6.5 12 4.6 6.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 KEY65401.1 - 7.4 6.1 18.7 23 4.4 18.7 1.8 1 0 0 1 1 1 0 PPP4R2 ANAPC1 PF12859.7 KEY65402.1 - 1.2e-37 129.3 0.1 1.2e-37 129.3 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KEY65402.1 - 0.0082 16.5 0.2 3.8 8.1 0.0 3.9 3 0 0 3 3 3 1 Proteasome/cyclosome repeat eIF3_N PF09440.10 KEY65403.1 - 1.9e-46 157.8 0.1 1.1e-45 155.4 0.8 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KEY65403.1 - 7.1e-14 52.2 0.0 1.8e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 KEY65403.1 - 0.045 14.6 0.3 14 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 KEY65403.1 - 1.7 8.8 4.0 39 4.5 0.1 3.2 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal Img2 PF05046.14 KEY65404.1 - 6e-21 74.5 0.1 1e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 KEY65405.1 - 5.5e-18 65.4 0.0 5.5e-18 65.4 0.0 2.6 2 1 0 2 2 2 1 ARID/BRIGHT DNA binding domain DDHD PF02862.17 KEY65405.1 - 4.7 7.3 18.3 0.8 9.8 13.8 1.9 2 0 0 2 2 2 0 DDHD domain U3_assoc_6 PF08640.11 KEY65406.1 - 2.3e-27 94.9 1.8 5.9e-26 90.4 0.6 2.9 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KEY65406.1 - 0.0013 17.9 3.2 0.0013 17.9 3.2 1.5 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Frag1 PF10277.9 KEY65407.1 - 1.4e-35 122.9 6.8 1.4e-35 122.9 6.8 2.8 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KEY65407.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 KEY65408.1 - 1.1e-59 202.5 0.0 1.7e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nucleoporin_FG PF13634.6 KEY65408.1 - 0.0016 19.2 27.8 0.0016 19.2 27.8 6.1 2 1 5 7 7 7 3 Nucleoporin FG repeat region Ribosomal_S10 PF00338.22 KEY65409.1 - 1e-26 93.0 0.2 1.2e-26 92.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 KEY65409.1 - 0.0015 17.2 0.1 0.0016 17.1 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein CUE PF02845.16 KEY65410.1 - 5.4e-10 38.8 0.1 1.1e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 KEY65410.1 - 0.23 10.8 1.7 0.39 10.0 1.7 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2 PF00096.26 KEY65411.1 - 2.5e-05 24.5 3.1 1.4 9.5 0.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 KEY65411.1 - 0.047 14.3 5.0 4.2 8.1 0.3 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KEY65411.1 - 0.18 12.7 0.0 0.18 12.7 0.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger GatB_N PF02934.15 KEY65412.1 - 3.9e-97 324.9 0.0 4.9e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KEY65412.1 - 5.5e-12 45.8 0.0 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 GatB domain Apolipoprotein PF01442.18 KEY65414.1 - 0.0029 17.5 6.4 0.0046 16.9 6.4 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 KEY65414.1 - 0.0038 17.3 4.1 0.0038 17.3 4.1 3.2 3 1 1 4 4 4 2 Late embryogenesis abundant protein CsbD PF05532.12 KEY65414.1 - 0.2 11.6 20.4 2.5e+02 1.7 19.0 4.2 1 1 0 1 1 1 0 CsbD-like DUF883 PF05957.13 KEY65414.1 - 0.31 11.7 8.0 0.6 10.7 5.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KEY65414.1 - 1.2 9.8 12.6 1 9.9 3.1 2.6 1 1 1 2 2 2 0 YtxH-like protein ATP-synt_B PF00430.18 KEY65414.1 - 2.3 8.3 11.6 4.6 7.3 11.6 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Gpr1_Fun34_YaaH PF01184.19 KEY65415.1 - 1.3e-57 194.7 15.6 1.8e-57 194.3 15.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF5134 PF17197.4 KEY65415.1 - 6.5 6.7 12.6 5.7 6.8 1.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5134) DUF3959 PF13105.6 KEY65415.1 - 9.8 5.6 7.3 15 5.0 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DnaJ PF00226.31 KEY65416.1 - 9.1e-09 35.3 1.1 1.7e-08 34.4 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain HCMV_UL124 PF17609.2 KEY65416.1 - 0.35 11.1 7.1 0.74 10.0 7.1 1.5 1 0 0 1 1 1 0 Family of unknown function SR-25 PF10500.9 KEY65416.1 - 7.4 6.1 8.1 12 5.4 8.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ECH_1 PF00378.20 KEY65417.1 - 1.3e-40 139.3 0.1 3.8e-38 131.2 0.0 2.8 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY65417.1 - 2.4e-24 86.4 0.1 2.5e-21 76.5 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase UCH PF00443.29 KEY65418.1 - 2.9e-40 138.4 0.0 5.2e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KEY65418.1 - 9.4e-08 31.9 2.8 0.017 15.0 0.1 3.9 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KEY65418.1 - 6.8e-05 22.6 8.4 0.001 18.7 8.4 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 KEY65420.1 - 1.7e-09 38.1 0.4 0.00088 19.8 0.1 4.5 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY65420.1 - 4.6e-08 32.7 1.5 0.08 13.5 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEY65420.1 - 5.9e-07 29.6 0.2 0.62 10.5 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY65420.1 - 1.4e-06 28.5 3.6 0.21 12.1 0.1 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KEY65420.1 - 2.3e-05 24.9 0.2 2.5 8.8 0.0 5.2 5 1 1 6 6 6 1 Ankyrin repeats (many copies) SDA1 PF05285.12 KEY65420.1 - 0.16 11.3 18.6 0.95 8.8 5.2 2.1 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.13 KEY65420.1 - 0.74 9.7 11.6 1.7 8.6 2.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KEY65420.1 - 1 8.6 16.2 1.4 8.2 2.2 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 KEY65420.1 - 2.4 6.4 15.8 0.99 7.6 3.8 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF1524 PF07510.11 KEY65421.1 - 1.3e-08 34.8 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KEY65421.1 - 0.18 11.8 0.0 9.7 6.2 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Glyco_hydro_16 PF00722.21 KEY65423.1 - 2.6e-06 27.0 0.1 0.025 14.1 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Sec7 PF01369.20 KEY65424.1 - 5.7e-29 101.1 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KEY65424.1 - 3.2e-21 75.9 0.0 1.1e-20 74.2 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KEY65424.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 PH domain FMO-like PF00743.19 KEY65425.1 - 2.8e-32 111.9 0.0 2.4e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY65425.1 - 9e-13 48.1 0.0 6.6e-12 45.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY65425.1 - 1.4e-11 44.2 0.0 3.2e-10 39.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY65425.1 - 1.3e-07 31.2 0.0 3.3e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY65425.1 - 7.9e-06 25.9 0.0 0.00033 20.7 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY65425.1 - 9.8e-05 22.5 0.1 0.00099 19.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEY65425.1 - 0.033 13.5 0.4 1.1 8.4 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 KEY65425.1 - 0.19 11.3 2.2 6.4 6.2 0.0 3.0 1 1 1 3 3 3 0 FAD dependent oxidoreductase Amidohydro_2 PF04909.14 KEY65427.1 - 6.2e-10 39.3 0.0 2.4e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KEY65427.1 - 0.0011 18.3 0.1 0.15 11.4 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family CoA_binding_2 PF13380.6 KEY65427.1 - 0.047 14.2 0.0 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain Glycos_transf_N PF04413.16 KEY65427.1 - 0.1 12.3 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) FTR_C PF02741.15 KEY65427.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FTR, proximal lobe Agouti PF05039.12 KEY65427.1 - 0.3 11.8 1.3 0.65 10.8 1.3 1.6 1 0 0 1 1 1 0 Agouti protein DUF676 PF05057.14 KEY65428.1 - 9.5e-05 22.0 0.1 0.00022 20.8 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY65428.1 - 0.0071 17.0 8.9 0.035 14.7 8.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.26 KEY65429.1 - 1.1e-14 54.5 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEY65429.1 - 0.0048 17.2 0.0 0.16 12.3 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5427 PF10310.9 KEY65429.1 - 3.6 6.5 11.8 5.9 5.7 11.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Di19_C PF14571.6 KEY65430.1 - 0.14 12.7 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal HAD_2 PF13419.6 KEY65431.1 - 8e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY65431.1 - 6.4e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY65431.1 - 0.00037 20.5 0.1 0.00071 19.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KEY65431.1 - 0.014 15.8 0.0 0.088 13.2 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HNH PF01844.23 KEY65432.1 - 0.0022 18.2 0.4 0.0046 17.1 0.4 1.6 1 1 0 1 1 1 1 HNH endonuclease DUF5418 PF17439.2 KEY65433.1 - 0.03 14.4 1.6 0.03 14.4 1.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Vma12 PF11712.8 KEY65433.1 - 0.042 13.9 1.0 0.096 12.8 1.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2070 PF09843.9 KEY65433.1 - 0.21 9.8 3.9 0.27 9.5 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF202 PF02656.15 KEY65433.1 - 1.5 9.3 4.8 2.7 8.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Polysacc_synt_C PF14667.6 KEY65433.1 - 4.4 7.4 9.5 4.3 7.4 8.1 1.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain FA_desaturase PF00487.24 KEY65435.1 - 3.1e-24 86.2 22.9 5.9e-24 85.3 22.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KEY65435.1 - 0.00017 21.8 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) OB_NTP_bind PF07717.16 KEY65436.1 - 1.5e-11 44.4 0.0 5.8e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEY65436.1 - 4.4e-07 30.1 0.0 8.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEY65436.1 - 1.5e-05 25.3 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KEY65436.1 - 0.00027 20.1 0.0 0.00068 18.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KEY65436.1 - 0.00062 20.1 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEY65436.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KEY65436.1 - 0.072 13.5 0.0 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Myosin_head PF00063.21 KEY65436.1 - 0.099 10.8 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) ABC_tran PF00005.27 KEY65436.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KEY65436.1 - 0.13 12.5 0.1 0.35 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY65436.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.18 KEY65437.1 - 1.4e-14 53.8 0.1 2.6e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65437.1 - 2.4e-06 27.5 11.7 2.4e-06 27.5 11.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KEY65438.1 - 7.4e-09 35.7 0.1 1.6e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 KEY65438.1 - 0.0098 15.5 0.7 0.014 15.0 0.7 1.2 1 0 0 1 1 1 1 NmrA-like family ADH_N PF08240.12 KEY65438.1 - 0.045 13.6 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KEY65441.1 - 3.7e-17 62.4 0.0 7.2e-15 55.0 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY65441.1 - 3.7e-07 29.9 0.2 6.3e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY65441.1 - 0.00013 22.0 1.7 0.00014 21.8 0.5 1.6 2 0 0 2 2 2 1 KR domain CorA PF01544.18 KEY65442.1 - 2.3e-07 30.4 2.5 2.3e-07 30.4 2.5 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ion_trans_N PF08412.10 KEY65442.1 - 0.15 11.7 0.2 0.6 9.8 0.1 2.1 2 0 0 2 2 2 0 Ion transport protein N-terminal DUF2614 PF11023.8 KEY65442.1 - 0.16 12.0 2.0 0.35 11.0 0.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain CBP4 PF07960.11 KEY65442.1 - 0.39 10.6 2.4 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 CBP4 Nop25 PF09805.9 KEY65442.1 - 0.82 10.1 7.5 1.9 9.0 4.0 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SDF PF00375.18 KEY65443.1 - 3.5e-88 296.3 30.2 4.3e-88 296.0 30.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Nuc_deoxyri_tr2 PF15891.5 KEY65444.1 - 1.6e-32 112.1 0.0 1.9e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like p450 PF00067.22 KEY65445.1 - 1.3e-73 248.4 0.0 1.7e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1206 PF06724.11 KEY65445.1 - 1.2 9.3 4.0 2.2 8.4 4.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Acetyltransf_1 PF00583.25 KEY65446.1 - 3.3e-09 37.0 0.1 4.2e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY65446.1 - 2.4e-07 31.1 0.2 3.4e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY65446.1 - 2.3e-06 27.6 0.2 3.3e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1100 PF06500.11 KEY65447.1 - 1.8e-14 53.4 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 KEY65447.1 - 3.4e-05 23.2 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY65447.1 - 0.00089 18.8 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family TPR_12 PF13424.6 KEY65447.1 - 0.0029 17.9 0.2 0.0076 16.5 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KEY65447.1 - 0.0084 16.7 2.6 0.0084 16.7 2.6 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family TPR_2 PF07719.17 KEY65447.1 - 0.012 15.6 1.3 0.028 14.5 1.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY65447.1 - 0.041 13.8 0.4 0.041 13.8 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BAAT_C PF08840.11 KEY65447.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KEY65447.1 - 0.062 13.1 0.0 2.2 8.1 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold TPR_MalT PF17874.1 KEY65447.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_8 PF13181.6 KEY65447.1 - 0.094 13.0 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY65447.1 - 0.1 13.3 0.5 0.1 13.3 0.5 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY65447.1 - 0.11 12.3 0.9 0.22 11.4 0.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KEY65448.1 - 5.1e-56 189.9 0.3 6e-56 189.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY65448.1 - 3.3e-50 170.3 0.0 4.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY65448.1 - 4.3e-12 46.3 0.4 8.8e-12 45.3 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY65448.1 - 3.1e-06 26.8 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY65448.1 - 0.0035 16.5 0.1 0.0072 15.5 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KEY65448.1 - 0.025 13.9 0.0 0.095 12.1 0.0 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LDcluster4 PF18306.1 KEY65448.1 - 0.14 11.7 0.9 0.28 10.7 0.1 1.8 2 0 0 2 2 2 0 SLOG cluster4 family Aldo_ket_red PF00248.21 KEY65449.1 - 9e-46 156.4 0.0 1e-43 149.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SNARE PF05739.19 KEY65450.1 - 4.7e-12 45.7 0.1 4.7e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KEY65450.1 - 5.3e-07 28.7 0.1 1.6e-06 27.2 0.1 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KEY65450.1 - 9.2e-05 22.7 7.0 0.023 15.0 0.3 3.7 4 0 0 4 4 4 2 Uncharacterized conserved protein Syntaxin PF00804.25 KEY65450.1 - 0.00026 20.7 8.3 0.00065 19.4 0.1 3.1 2 1 1 3 3 3 1 Syntaxin TRPM_tetra PF16519.5 KEY65450.1 - 0.0051 16.9 1.4 0.019 15.0 0.1 2.7 3 0 0 3 3 3 1 Tetramerisation domain of TRPM Prominin PF05478.11 KEY65450.1 - 0.01 13.8 1.8 1.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 KEY65450.1 - 0.064 13.5 0.6 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4988 PF16378.5 KEY65450.1 - 0.079 12.6 5.0 3 7.5 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KEY65450.1 - 0.087 13.3 5.1 29 5.2 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 KEY65450.1 - 0.088 12.6 7.4 0.075 12.8 1.3 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 KEY65450.1 - 0.19 12.0 1.4 5.1 7.4 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 KEY65450.1 - 0.31 11.5 3.8 9.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin DUF2408 PF10303.9 KEY65450.1 - 2.3 8.8 7.7 1.6 9.3 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) O_Spanin_T7 PF17531.2 KEY65451.1 - 5.2 7.2 7.5 2.3 8.4 3.5 2.7 2 0 0 2 2 2 0 outer-membrane spanin sub-unit DUF720 PF05302.11 KEY65452.1 - 0.56 10.1 8.8 1.1 9.1 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF4638 PF15472.6 KEY65452.1 - 9.6 5.8 6.1 1.3 8.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4638) BTB PF00651.31 KEY65453.1 - 0.00014 22.1 0.0 0.00075 19.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Nrap_D5 PF17406.2 KEY65456.1 - 0.035 13.8 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Sec2p PF06428.11 KEY65457.1 - 1.4e-26 92.3 25.5 2.6e-26 91.4 20.0 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Med9 PF07544.13 KEY65457.1 - 0.057 13.5 9.7 1.5 9.0 0.2 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-Mss51 PF13824.6 KEY65457.1 - 0.44 10.7 1.5 4.3 7.5 1.5 2.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.6 KEY65457.1 - 0.54 11.2 1.6 3.2 8.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger CENP-Q PF13094.6 KEY65457.1 - 0.64 10.2 25.2 1.8 8.7 4.7 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3584 PF12128.8 KEY65457.1 - 1.4 6.4 24.0 1.9 5.9 24.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C2H2 PF00096.26 KEY65457.1 - 1.4 9.5 3.2 0.47 11.0 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4407 PF14362.6 KEY65457.1 - 4.4 6.6 16.6 8.1 5.7 16.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 KEY65457.1 - 8.8 5.5 10.0 14 4.9 10.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PMT PF02366.18 KEY65458.1 - 6e-80 268.4 15.5 6e-80 268.4 15.5 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEY65458.1 - 7.7e-67 224.7 12.8 7.7e-67 224.7 12.8 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEY65458.1 - 3.3e-47 160.7 0.0 5.9e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.8 KEY65459.1 - 3.6e-52 177.4 15.2 8.2e-51 172.9 15.2 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KEY65459.1 - 2.5e-37 126.7 1.4 6.3e-18 64.5 0.0 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KEY65459.1 - 0.021 14.4 0.3 0.037 13.6 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Hus1 PF04005.12 KEY65459.1 - 0.14 11.3 0.1 0.26 10.4 0.1 1.4 1 0 0 1 1 1 0 Hus1-like protein PX PF00787.24 KEY65460.1 - 1.7e-23 82.8 0.0 2.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 KEY65461.1 - 3.4e-73 241.7 1.7 8e-26 89.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY65461.1 - 0.00033 19.9 0.4 0.025 13.7 0.0 2.6 2 1 0 2 2 2 2 Gammaproteobacterial serine protease HMD PF03201.16 KEY65461.1 - 0.078 13.2 0.0 46 4.3 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Zn_clus PF00172.18 KEY65462.1 - 0.027 14.6 12.6 0.048 13.8 12.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3660 PF12398.8 KEY65464.1 - 0.14 12.2 0.1 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 Receptor serine/threonine kinase PQ-loop PF04193.14 KEY65466.1 - 5.1e-18 64.6 0.8 9.8e-13 47.7 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat CLLAC PF15675.5 KEY65466.1 - 0.55 9.8 3.6 2.6 7.6 2.0 2.6 2 0 0 2 2 2 0 CLLAC-motif containing domain eIF3_subunit PF08597.10 KEY65467.1 - 5.2e-05 23.3 1.7 8.2e-05 22.6 1.7 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 KEY65467.1 - 0.26 11.7 4.9 0.57 10.6 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MTHFR PF02219.17 KEY65468.1 - 1.4e-101 339.7 0.0 1.9e-101 339.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase tRNA-synt_1 PF00133.22 KEY65469.1 - 1.1e-47 162.7 0.0 1.5e-15 56.5 0.1 6.1 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KEY65469.1 - 1.2e-37 129.2 0.0 2.7e-37 128.1 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KEY65469.1 - 1.1e-29 103.4 0.2 1.1e-21 77.0 0.0 4.9 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEY65469.1 - 7.8e-12 45.4 0.0 1.9e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEY65469.1 - 0.0032 16.9 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 KEY65469.1 - 0.34 10.4 3.2 2 7.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PQ-loop PF04193.14 KEY65470.1 - 2.6e-25 87.9 10.4 7.5e-15 54.5 0.4 3.2 3 0 0 3 3 3 2 PQ loop repeat Mito_carr PF00153.27 KEY65471.1 - 2.4e-71 235.7 1.0 1.4e-25 89.0 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KEY65471.1 - 2e-17 61.4 6.7 9.8e-06 24.8 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KEY65471.1 - 3.7e-16 57.6 1.1 3.9e-05 23.3 0.1 5.8 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.6 KEY65471.1 - 9e-15 54.9 5.5 2.8e-06 27.7 0.4 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KEY65471.1 - 3.5e-13 48.4 2.5 0.0036 16.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KEY65471.1 - 3e-09 36.6 3.9 0.062 13.2 0.0 5.4 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_9 PF14658.6 KEY65471.1 - 0.015 15.6 0.1 21 5.5 0.0 3.9 4 1 1 5 5 5 0 EF-hand domain Cyclin_N PF00134.23 KEY65472.1 - 7.4e-44 148.6 0.1 4.8e-43 145.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEY65472.1 - 6e-36 123.1 0.1 1.5e-35 121.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pyr_redox PF00070.27 KEY65472.1 - 0.14 12.7 0.1 0.74 10.4 0.1 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KEY65474.1 - 0.00073 19.6 12.2 0.0013 18.8 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KEY65474.1 - 0.041 13.4 0.1 0.041 13.4 0.1 3.4 4 0 0 4 4 4 0 Histone chaperone domain CHZ MFS_1 PF07690.16 KEY65475.1 - 9.9e-27 93.8 46.7 9.9e-27 93.8 46.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY65475.1 - 0.001 18.0 13.5 0.001 18.0 13.5 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2752 PF10825.8 KEY65475.1 - 0.33 11.0 3.2 0.34 11.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Abhydrolase_3 PF07859.13 KEY65476.1 - 1.7e-05 24.8 1.1 0.074 12.9 0.1 3.2 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY65476.1 - 9.3e-05 23.1 0.3 0.00013 22.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KEY65476.1 - 0.039 14.1 0.0 0.09 12.9 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Hydrolase_4 PF12146.8 KEY65476.1 - 0.048 12.9 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PAE PF03283.13 KEY65476.1 - 0.1 11.7 0.0 0.81 8.7 0.0 1.9 2 0 0 2 2 2 0 Pectinacetylesterase DUF3089 PF11288.8 KEY65476.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RTA1 PF04479.13 KEY65478.1 - 9.9e-67 224.5 11.8 1.4e-66 224.1 11.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.9 KEY65478.1 - 0.066 13.3 4.0 0.066 13.2 2.2 2.1 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2165) Amastin PF07344.11 KEY65478.1 - 6.3 6.6 11.6 13 5.6 1.0 2.9 1 1 1 2 2 2 0 Amastin surface glycoprotein RNA_pol_Rpc4 PF05132.14 KEY65479.1 - 1.8e-32 112.8 2.5 7.5e-31 107.6 0.1 3.2 3 0 0 3 3 3 2 RNA polymerase III RPC4 UreD PF01774.17 KEY65480.1 - 9.1e-73 244.7 0.0 1.1e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 KEY65481.1 - 3.1e-35 120.5 0.9 1.3e-34 118.5 0.9 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KEY65481.1 - 0.00019 21.8 1.8 0.0036 17.7 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KEY65481.1 - 0.0052 16.9 0.0 13 6.3 0.0 4.9 4 1 1 5 5 5 1 HEAT repeat POT1PC PF16686.5 KEY65482.1 - 4.4e-40 137.1 0.0 1.5e-39 135.3 0.0 1.9 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KEY65482.1 - 1.3e-15 57.5 0.0 2.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 KEY65482.1 - 0.00095 19.0 0.0 0.042 13.8 0.0 2.7 2 0 0 2 2 2 1 Replication protein A OB domain YkyA PF10368.9 KEY65482.1 - 1.2 8.8 5.2 2.2 7.9 5.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein RcpC PF16976.5 KEY65482.1 - 1.2 9.2 6.3 4 7.5 4.1 2.5 1 1 1 2 2 2 0 Flp pilus assembly protein RcpC/CpaB DUF1682 PF07946.14 KEY65482.1 - 5.7 6.0 8.9 10 5.2 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Arm PF00514.23 KEY65483.1 - 7.7e-98 317.9 15.8 9.6e-14 50.9 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KEY65483.1 - 3.3e-28 98.0 3.0 1.1e-27 96.3 1.6 2.3 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KEY65483.1 - 2.8e-23 81.2 4.3 6.6e-23 80.0 3.8 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KEY65483.1 - 7e-21 74.3 8.0 2.2e-07 31.2 0.1 6.3 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KEY65483.1 - 2.9e-19 69.2 0.1 4e-08 33.6 0.1 5.2 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KEY65483.1 - 1.7e-18 65.1 2.2 6.4e-05 22.9 0.0 7.0 8 0 0 8 8 7 4 HEAT repeat Arm_2 PF04826.13 KEY65483.1 - 4.4e-07 29.6 0.0 0.036 13.5 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KEY65483.1 - 8e-06 24.7 0.0 0.00083 18.0 0.0 2.2 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KEY65483.1 - 0.00017 21.7 0.0 3.6 7.7 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 KEY65483.1 - 0.00041 20.7 0.2 1.7 9.6 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KEY65483.1 - 0.0022 18.1 0.0 4.2 7.4 0.0 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 KEY65483.1 - 0.004 16.8 0.0 4.3 6.9 0.0 4.0 2 2 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KEY65483.1 - 0.005 17.0 5.0 3.1 8.1 0.0 5.1 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 KEY65483.1 - 0.035 13.9 0.0 6.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NUSAP PF16006.5 KEY65483.1 - 6.8 6.3 6.4 9.6 5.9 6.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein zf-C2HE PF16278.5 KEY65484.1 - 5.9e-17 61.9 0.1 1.6e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Helicase_C PF00271.31 KEY65484.1 - 1.2e-16 61.0 0.0 3.9e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KEY65484.1 - 1.9e-16 60.3 0.8 1.1e-15 57.9 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY65484.1 - 1e-14 54.6 0.0 3.1e-14 53.1 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HIT PF01230.23 KEY65484.1 - 2.7e-14 53.7 0.0 7.8e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEY65484.1 - 1e-12 48.6 5.9 2.3e-11 44.2 5.9 2.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.29 KEY65484.1 - 1.2e-10 41.4 0.1 3.1e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY65484.1 - 0.00034 20.9 1.1 0.002 18.4 1.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KEY65484.1 - 0.00046 20.2 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DND1_DSRM PF14709.7 KEY65484.1 - 0.0034 17.6 0.3 0.012 15.9 0.3 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RWD PF05773.22 KEY65484.1 - 0.0039 17.5 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain ATPase PF06745.13 KEY65484.1 - 0.0044 16.4 0.2 0.012 15.0 0.2 1.7 1 1 0 1 1 1 1 KaiC UBA PF00627.31 KEY65484.1 - 0.007 16.2 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain AAA_29 PF13555.6 KEY65484.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEY65484.1 - 0.015 15.8 0.7 0.091 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain dsRBD2 PF17842.1 KEY65484.1 - 0.027 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 AT_hook PF02178.19 KEY65485.1 - 0.065 13.1 4.5 0.065 13.1 4.5 5.0 4 0 0 4 4 4 0 AT hook motif Cwf_Cwc_15 PF04889.12 KEY65485.1 - 0.68 9.6 11.1 0.87 9.3 11.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Kinesin PF00225.23 KEY65486.1 - 2.1e-115 385.2 0.0 3.6e-115 384.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEY65486.1 - 1.4e-24 86.7 0.0 1.4e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 KEY65486.1 - 0.0034 16.3 7.7 0.0059 15.5 7.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein PriC PF07445.12 KEY65486.1 - 0.0078 16.2 7.6 0.02 14.9 7.6 1.6 1 0 0 1 1 1 1 Primosomal replication protein priC YabA PF06156.13 KEY65486.1 - 0.041 14.5 8.0 4.4 8.0 2.4 3.8 3 1 1 4 4 4 0 Initiation control protein YabA Noggin PF05806.12 KEY65486.1 - 0.19 11.6 1.0 8 6.3 0.3 2.7 2 0 0 2 2 2 0 Noggin Tau95 PF09734.9 KEY65486.1 - 0.19 12.5 1.9 0.55 11.0 1.9 1.7 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF2018 PF09442.10 KEY65486.1 - 0.37 11.8 7.1 0.48 11.4 3.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) HAUS6_N PF14661.6 KEY65486.1 - 0.37 10.3 5.4 0.96 9.0 5.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF87 PF01935.17 KEY65486.1 - 0.72 9.9 0.0 0.72 9.9 0.0 3.2 3 1 0 3 3 3 0 Helicase HerA, central domain MFS_1 PF07690.16 KEY65489.1 - 1.3e-20 73.6 44.7 1.2e-19 70.5 43.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1484 PF07363.11 KEY65491.1 - 0.0043 18.0 0.6 0.02 15.9 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1484) Borrelia_REV PF03978.13 KEY65491.1 - 0.0082 16.1 0.7 1.1 9.2 0.8 2.4 2 0 0 2 2 2 1 Borrelia burgdorferi REV protein Fib_alpha PF08702.10 KEY65491.1 - 0.031 14.5 4.1 0.059 13.6 0.2 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SesA PF17107.5 KEY65491.1 - 0.13 12.5 1.4 0.36 11.0 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Prefoldin_3 PF13758.6 KEY65491.1 - 0.78 9.8 5.1 1.8 8.7 0.3 2.9 3 1 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 KEY65491.1 - 3.6 7.6 6.0 11 6.0 4.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMRT-like PF15791.5 KEY65492.1 - 0.27 11.7 0.0 0.27 11.7 0.0 3.1 3 0 0 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 DUF2235 PF09994.9 KEY65493.1 - 3.3e-44 151.4 0.0 4.5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4483 PF14825.6 KEY65493.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) TPR_10 PF13374.6 KEY65494.1 - 1.8e-88 288.3 1.3 2.3e-11 43.2 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65494.1 - 5.2e-66 218.9 9.6 8.7e-13 48.4 0.0 8.0 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65494.1 - 7.8e-22 75.7 5.0 0.039 14.0 0.0 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_4 PF07721.14 KEY65494.1 - 6.3e-12 44.9 1.3 0.085 13.5 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY65494.1 - 8.5e-11 41.8 8.9 8.9e-07 28.6 2.1 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KEY65494.1 - 2.1e-10 40.0 0.0 0.3 11.0 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65494.1 - 4.3e-10 38.9 6.1 0.041 14.0 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEY65494.1 - 1.6e-09 37.5 0.0 2.8 8.5 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY65494.1 - 9.6e-08 32.6 0.0 20 5.9 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY65494.1 - 1.9e-06 28.3 0.5 8.6 6.9 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 KEY65494.1 - 0.00017 21.5 0.0 0.19 11.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Trans_reg_C PF00486.28 KEY65494.1 - 0.00019 21.5 0.1 1.8 8.7 0.0 3.9 3 1 1 4 4 4 1 Transcriptional regulatory protein, C terminal TPR_8 PF13181.6 KEY65494.1 - 0.0011 19.0 0.7 25 5.4 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65494.1 - 0.004 17.9 3.5 1.8e+02 3.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4119 PF13494.6 KEY65494.1 - 0.0098 16.0 0.0 1.1e+02 3.1 0.0 4.8 4 1 0 4 4 4 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF1897 PF09005.10 KEY65494.1 - 0.016 14.6 1.7 18 4.9 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) DUF3660 PF12398.8 KEY65494.1 - 0.064 13.3 0.0 23 5.1 0.0 4.1 5 0 0 5 5 5 0 Receptor serine/threonine kinase NdhL PF10716.9 KEY65494.1 - 0.56 10.2 2.9 15 5.6 0.1 3.1 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Tyrosinase PF00264.20 KEY65496.1 - 3.9e-32 112.4 11.9 5e-32 112.0 10.5 1.9 2 1 0 2 2 2 1 Common central domain of tyrosinase DUF3357 PF11837.8 KEY65496.1 - 0.035 14.6 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Gly-zipper_Omp PF13488.6 KEY65496.1 - 0.1 12.6 0.7 0.17 11.9 0.7 1.3 1 0 0 1 1 1 0 Glycine zipper DUF2613 PF11021.8 KEY65496.1 - 0.16 12.1 0.6 0.28 11.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Glyco_hydro_61 PF03443.14 KEY65497.1 - 1.3e-43 149.3 0.0 1.8e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY65497.1 - 3.8e-11 42.7 13.1 1.1e-10 41.3 13.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEY65497.1 - 0.13 12.5 7.8 0.39 11.0 7.8 1.9 1 1 0 1 1 1 0 Toxin 7 WSC PF01822.19 KEY65498.1 - 0.0096 16.1 4.3 0.015 15.5 4.3 1.3 1 0 0 1 1 1 1 WSC domain PCMT PF01135.19 KEY65499.1 - 7.2e-44 150.1 0.0 9.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEY65499.1 - 6.1e-06 26.1 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEY65499.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65499.1 - 0.0059 17.3 0.0 0.016 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEY65499.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.6 KEY65499.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65499.1 - 0.064 13.9 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEY65499.1 - 0.19 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2370 PF10176.9 KEY65500.1 - 7.3e-89 297.3 0.0 1.3e-88 296.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 KEY65502.1 - 1.5e-51 172.3 3.3 8.2e-22 76.9 0.4 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Ank_2 PF12796.7 KEY65504.1 - 8.4e-25 87.2 0.0 8.4e-09 35.9 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY65504.1 - 4.3e-17 62.3 1.7 6.8e-06 26.5 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY65504.1 - 1.2e-13 49.9 1.6 0.002 18.5 0.3 5.8 5 2 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KEY65504.1 - 1.1e-12 48.0 0.5 2.4e-07 30.9 0.5 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY65504.1 - 1.1e-09 38.2 1.5 0.043 14.3 1.2 5.7 6 1 0 6 6 6 2 Ankyrin repeat DUF3263 PF11662.8 KEY65504.1 - 0.066 13.1 0.1 0.4 10.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3263) adh_short PF00106.25 KEY65505.1 - 1.2e-42 145.6 0.3 1.4e-42 145.4 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY65505.1 - 3.9e-36 124.8 1.8 4.6e-36 124.5 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY65505.1 - 5.2e-15 55.8 0.6 6.8e-15 55.4 0.6 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KEY65505.1 - 0.0076 16.8 0.5 0.016 15.8 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2 PF00096.26 KEY65507.1 - 8.6e-06 25.9 26.6 0.0064 16.9 2.7 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY65507.1 - 7.5e-05 23.2 26.9 0.17 12.8 0.2 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KEY65507.1 - 0.037 13.8 0.3 0.037 13.8 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KEY65507.1 - 0.31 11.4 3.1 9.4 6.7 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding UBZ_FAAP20 PF15750.5 KEY65507.1 - 2.2 8.3 4.1 0.61 10.1 0.1 2.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Sina PF03145.16 KEY65507.1 - 5.5 6.9 10.5 11 5.8 10.5 1.5 1 0 0 1 1 1 0 Seven in absentia protein family zf-Di19 PF05605.12 KEY65507.1 - 8.4 6.8 15.3 1.3 9.3 0.2 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KEY65507.1 - 8.7 6.7 11.7 6.1 7.2 0.2 3.3 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4238 PF14022.6 KEY65508.1 - 5.1e-24 85.2 0.7 1.1e-23 84.2 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) HSBP1 PF06825.12 KEY65508.1 - 0.0082 16.0 2.2 2.7 7.9 0.1 2.5 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Pkinase PF00069.25 KEY65509.1 - 7e-08 32.1 0.0 8.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KEY65509.1 - 0.00068 19.0 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY65509.1 - 0.00085 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEY65509.1 - 0.0058 16.3 0.1 0.0089 15.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KEY65509.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KEY65509.1 - 0.037 13.9 0.9 0.073 13.0 0.9 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KEY65509.1 - 0.071 12.4 0.1 0.091 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KEY65509.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Coq4 PF05019.13 KEY65511.1 - 4.8e-95 317.1 0.0 5.8e-95 316.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 KEY65512.1 - 1.7e-42 144.2 10.8 2e-42 144.0 10.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA_C PF08546.11 KEY65513.1 - 2.5e-16 60.0 0.0 5.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KEY65513.1 - 8.7e-13 48.2 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 KEY65514.1 - 3.4e-14 53.2 0.6 5.6e-14 52.5 0.1 1.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2076 PF09849.9 KEY65515.1 - 9.3e-08 32.4 11.5 1.3e-07 31.9 11.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KEY65515.1 - 0.00017 21.7 3.4 0.00025 21.1 3.4 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KEY65515.1 - 0.064 13.7 1.1 0.12 12.8 1.1 1.5 1 1 0 1 1 1 0 GCK domain COX6B PF02297.17 KEY65515.1 - 0.099 12.9 2.3 0.14 12.4 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UBX PF00789.20 KEY65516.1 - 1.5e-15 57.2 0.0 3.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.12 KEY65516.1 - 0.06 12.0 9.9 0.0029 16.4 4.6 1.4 2 0 0 2 2 2 0 Hamartin protein DUF1654 PF07867.11 KEY65516.1 - 1.9 8.3 5.2 1.7 8.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) Asp-B-Hydro_N PF05279.11 KEY65516.1 - 7.4 6.6 13.8 13 5.7 13.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Aldo_ket_red PF00248.21 KEY65517.1 - 1.8e-50 171.8 0.0 3e-50 171.1 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Homeobox_KN PF05920.11 KEY65517.1 - 0.005 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF676 PF05057.14 KEY65518.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KEY65518.1 - 8.3e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEY65518.1 - 2.6e-05 24.9 0.4 0.00012 22.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 KEY65518.1 - 0.0003 21.0 0.0 0.21 11.9 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain 6PF2K PF01591.18 KEY65518.1 - 0.0025 17.2 0.0 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Abhydrolase_1 PF00561.20 KEY65518.1 - 0.0048 16.6 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Frtz PF11768.8 KEY65518.1 - 0.011 14.2 0.0 0.018 13.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Hydrolase_4 PF12146.8 KEY65518.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_2 PF01674.18 KEY65518.1 - 0.065 12.7 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 2) APS_kinase PF01583.20 KEY65518.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF900 PF05990.12 KEY65518.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 KEY65518.1 - 0.19 11.3 0.1 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Alanine_zipper PF11839.8 KEY65519.1 - 3.9 7.9 10.3 15 6.0 10.3 2.0 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein RasGAP_C PF03836.15 KEY65520.1 - 0.00079 19.6 1.3 0.0012 19.0 1.3 1.2 1 0 0 1 1 1 1 RasGAP C-terminus DUF2203 PF09969.9 KEY65520.1 - 0.05 14.3 0.8 0.099 13.4 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LPP20 PF02169.16 KEY65520.1 - 0.074 13.4 1.7 0.15 12.4 1.7 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein DivIC PF04977.15 KEY65520.1 - 0.095 12.5 3.1 0.2 11.5 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Lectin_N PF03954.14 KEY65520.1 - 0.76 9.5 3.7 7.5 6.3 1.7 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain YabA PF06156.13 KEY65520.1 - 1.2 9.8 4.5 0.69 10.6 2.5 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Nuf2 PF03800.14 KEY65521.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Nuf2 family SURF1 PF02104.15 KEY65522.1 - 4e-47 160.7 0.0 5.1e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KEY65523.1 - 1.8e-40 137.4 0.1 1.6e-39 134.3 0.0 2.5 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KEY65523.1 - 8e-08 32.7 0.1 4e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KEY65523.1 - 2.3e-07 31.1 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KEY65523.1 - 0.026 14.8 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cu-oxidase_2 PF07731.14 KEY65525.1 - 2.4e-26 92.1 3.1 8.8e-23 80.6 1.4 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY65525.1 - 3.6e-21 75.4 0.1 1.3e-20 73.6 0.1 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY65525.1 - 0.00075 19.7 0.0 0.12 12.5 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Amidase PF01425.21 KEY65526.1 - 1.8e-97 327.2 0.0 1.3e-96 324.3 0.0 2.2 2 1 0 2 2 2 1 Amidase RNase_H PF00075.24 KEY65527.1 - 2.6e-18 66.6 0.0 4.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNase H F-box-like PF12937.7 KEY65527.1 - 1.7e-06 27.8 0.4 4e-06 26.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY65527.1 - 0.0076 16.1 1.7 0.0091 15.9 0.2 2.1 2 0 0 2 2 2 1 F-box domain RVT_3 PF13456.6 KEY65527.1 - 0.069 13.0 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Fungal_trans_2 PF11951.8 KEY65528.1 - 2.4e-07 29.9 1.4 3.7e-07 29.3 1.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KEY65529.1 - 1.6e-13 50.3 0.0 3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65529.1 - 4.2e-07 30.0 9.6 6.5e-07 29.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.6 KEY65529.1 - 0.0048 16.9 1.0 0.0091 16.0 1.0 1.4 1 0 0 1 1 1 1 FlxA-like protein MFS_1 PF07690.16 KEY65530.1 - 1.2e-32 113.2 77.3 3e-25 88.9 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY65530.1 - 2.8e-05 23.2 39.4 0.03 13.2 6.1 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 KEY65530.1 - 0.023 13.6 20.1 0.26 10.1 8.7 3.5 2 2 1 3 3 3 0 MFS_1 like family TraT PF05818.12 KEY65530.1 - 9.5 5.8 6.3 9.7 5.8 2.1 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein HET PF06985.11 KEY65531.1 - 3.1e-22 79.5 2.3 3.7e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Coilin_N PF15862.5 KEY65531.1 - 0.15 11.9 6.9 0.69 9.7 6.2 2.1 2 0 0 2 2 2 0 Coilin N-terminus DUF913 PF06025.12 KEY65531.1 - 0.26 10.2 2.5 0.34 9.8 2.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 KEY65531.1 - 1.4 8.4 22.9 2 7.9 22.9 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 KEY65531.1 - 2 7.7 26.1 2.6 7.4 26.1 1.1 1 0 0 1 1 1 0 SDA1 EzrA PF06160.12 KEY65532.1 - 0.18 10.0 4.2 0.58 8.3 1.9 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KEY65532.1 - 0.49 10.5 6.7 0.51 10.4 2.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Latarcin PF10279.9 KEY65532.1 - 1.9 8.9 6.2 0.84 10.1 2.3 2.4 2 0 0 2 2 2 0 Latarcin precursor HIP1_clath_bdg PF16515.5 KEY65532.1 - 2.1 9.0 6.6 0.6 10.8 3.2 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA PF00004.29 KEY65533.1 - 1.7e-16 60.8 0.0 7.7e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY65533.1 - 0.00013 22.2 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY65533.1 - 0.0013 19.3 0.0 0.0073 16.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY65533.1 - 0.0014 18.7 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEY65533.1 - 0.0022 18.4 0.0 0.0083 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KEY65533.1 - 0.035 14.2 0.0 0.19 11.8 0.0 2.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.12 KEY65533.1 - 0.041 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KEY65533.1 - 0.064 13.4 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEY65533.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KEY65533.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KEY65533.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Torsin SLC12 PF03522.15 KEY65533.1 - 2.9 6.8 7.9 5.9 5.8 7.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 KEY65533.1 - 6.3 6.3 9.2 23 4.5 9.3 1.9 1 1 0 1 1 1 0 Spt20 family PAN_4 PF14295.6 KEY65535.1 - 0.018 15.0 0.3 0.042 13.8 0.3 1.7 1 0 0 1 1 1 0 PAN domain Pkinase PF00069.25 KEY65536.1 - 8.2e-19 68.0 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65536.1 - 5.1e-12 45.6 0.0 1e-11 44.6 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KEY65536.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY65536.1 - 0.0023 17.9 0.0 0.0062 16.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY65536.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KEY65536.1 - 0.058 12.9 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 KEY65536.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 KEY65537.1 - 2.1e-19 69.8 0.0 3.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY65537.1 - 2.4e-19 69.8 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KEY65537.1 - 0.0046 16.6 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KEY65537.1 - 0.041 13.8 0.3 0.084 12.8 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_5 PF13857.6 KEY65538.1 - 4e-08 33.4 0.0 0.00021 21.5 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KEY65538.1 - 5.2e-08 32.4 0.2 3.8e-07 29.6 0.2 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 KEY65538.1 - 3.3e-07 30.8 0.2 2.2e-06 28.2 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KEY65538.1 - 4.1e-07 30.6 0.9 5.2e-06 26.9 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain Ank_4 PF13637.6 KEY65538.1 - 2.4e-05 24.8 0.0 5.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY65538.1 - 7e-05 22.9 0.0 1.1 10.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 KEY65538.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KEY65538.1 - 0.0019 18.6 0.0 0.48 11.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 KEY65538.1 - 0.002 18.4 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY65538.1 - 0.012 16.0 0.0 0.049 14.1 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEY65538.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 KEY65539.1 - 0.0019 18.1 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Thiolase_N PF00108.23 KEY65541.1 - 1e-86 290.5 0.8 1e-86 290.5 0.8 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY65541.1 - 8.7e-39 132.0 1.2 3e-38 130.2 1.2 2.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEY65541.1 - 0.00032 20.4 0.7 0.003 17.2 0.4 2.3 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEY65541.1 - 3.1 7.7 5.8 8.3 6.3 0.2 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 KEY65542.1 - 1.7e-52 176.8 0.1 1.9e-52 176.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY65542.1 - 0.00096 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEY65542.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 KEY65543.1 - 8.2e-114 380.0 0.3 8.2e-114 380.0 0.3 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEY65543.1 - 5.3e-26 91.3 0.0 1.9e-25 89.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding ERG2_Sigma1R PF04622.12 KEY65543.1 - 0.099 12.0 0.9 0.54 9.6 0.0 2.6 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein DUF3349 PF11829.8 KEY65543.1 - 6.8 7.5 7.6 3.6 8.4 0.8 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) LCM PF04072.14 KEY65545.1 - 5.3e-22 78.7 0.0 1e-21 77.8 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 KEY65546.1 - 6.4e-30 103.0 2.6 1.4e-29 101.9 0.2 2.4 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Clat_adaptor_s PF01217.20 KEY65547.1 - 1.1e-55 187.5 1.8 1.2e-55 187.3 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.6 KEY65548.1 - 0.0024 17.6 2.2 0.0049 16.7 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Ist1 PF03398.14 KEY65549.1 - 1.1e-60 204.4 0.6 1.4e-60 203.9 0.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PDZ_1 PF12812.7 KEY65550.1 - 6.4e-56 186.3 0.1 1e-34 118.4 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KEY65550.1 - 1e-21 78.4 0.9 4.5e-19 69.8 0.2 2.8 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KEY65550.1 - 1.9e-14 53.7 1.4 3.2e-06 27.4 0.1 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KEY65550.1 - 9.4e-13 47.8 0.3 0.0022 17.8 0.1 4.7 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KEY65550.1 - 1.8e-07 31.4 0.0 0.00085 19.6 0.0 3.7 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KEY65550.1 - 0.0015 18.5 0.9 0.78 9.7 0.1 4.0 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KEY65550.1 - 0.084 12.6 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KEY65550.1 - 0.1 11.2 0.1 0.2 10.2 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 Myb_DNA-binding PF00249.31 KEY65551.1 - 0.00036 20.7 0.1 0.0007 19.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DnaJ PF00226.31 KEY65552.1 - 6.3e-22 77.5 1.9 1.3e-21 76.5 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain Nop10p PF04135.12 KEY65552.1 - 0.72 9.9 2.8 1.1 9.4 0.9 2.3 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family RIBIOP_C PF04950.12 KEY65553.1 - 2e-93 313.0 3.4 6.4e-93 311.4 0.0 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KEY65553.1 - 5.1e-28 97.0 0.0 1.6e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KEY65553.1 - 7.2e-06 26.3 0.2 4.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY65553.1 - 2.6e-05 24.7 0.1 0.00011 22.6 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 KEY65553.1 - 0.00018 22.0 5.2 0.011 16.3 0.0 4.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KEY65553.1 - 0.00021 21.3 0.0 0.00079 19.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KEY65553.1 - 0.00023 21.1 0.1 0.00093 19.1 0.0 2.1 2 1 0 2 2 2 1 NACHT domain GTP_EFTU PF00009.27 KEY65553.1 - 0.00033 20.2 0.0 0.13 11.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KEY65553.1 - 0.00035 21.1 0.3 0.0014 19.2 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_33 PF13671.6 KEY65553.1 - 0.00053 20.2 0.6 0.0013 18.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KEY65553.1 - 0.00061 20.2 0.0 0.0018 18.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEY65553.1 - 0.003 17.9 0.0 0.0098 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY65553.1 - 0.0045 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KEY65553.1 - 0.0068 16.2 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KEY65553.1 - 0.0077 16.5 0.8 0.018 15.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KEY65553.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.14 KEY65553.1 - 0.017 15.0 0.2 0.93 9.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 KEY65553.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KEY65553.1 - 0.021 15.2 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KEY65553.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 KEY65553.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KEY65553.1 - 0.029 14.4 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 KEY65553.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KEY65553.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEY65553.1 - 0.043 13.7 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 KEY65553.1 - 0.043 13.7 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KEY65553.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEY65553.1 - 0.083 13.3 0.0 0.083 13.3 0.0 2.9 3 0 0 3 3 1 0 AAA domain AAA_5 PF07728.14 KEY65553.1 - 0.095 12.7 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEY65553.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KEY65553.1 - 0.15 12.1 0.0 1.2 9.1 0.0 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KEY65553.1 - 1.9 9.0 0.0 1.9 9.0 0.0 4.3 3 1 0 3 3 2 0 AAA domain DASH_Ask1 PF08655.10 KEY65555.1 - 5.7e-22 77.4 0.1 9.7e-22 76.6 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 GCP_C_terminal PF04130.13 KEY65556.1 - 3.8e-72 243.4 3.3 3.8e-72 243.4 3.3 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEY65556.1 - 2.8e-29 102.7 0.0 6.1e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Eaf7 PF07904.13 KEY65557.1 - 1.1e-26 93.3 0.2 1.1e-26 93.3 0.2 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Sporozoite_P67 PF05642.11 KEY65557.1 - 0.041 12.0 4.0 0.065 11.3 4.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pex2_Pex12 PF04757.14 KEY65557.1 - 0.2 11.2 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region PPP4R2 PF09184.11 KEY65557.1 - 0.53 9.8 7.7 0.84 9.2 7.7 1.3 1 0 0 1 1 1 0 PPP4R2 API5 PF05918.11 KEY65557.1 - 1.2 7.8 9.3 1.5 7.5 9.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NOA36 PF06524.12 KEY65557.1 - 1.5 8.0 6.6 2.7 7.2 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein RskA PF10099.9 KEY65557.1 - 1.6 9.0 21.6 0.033 14.5 13.8 2.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA FAM176 PF14851.6 KEY65557.1 - 3 7.5 5.6 7.4 6.2 5.6 1.6 1 0 0 1 1 1 0 FAM176 family ResIII PF04851.15 KEY65559.1 - 3.6e-23 82.4 0.0 9.8e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY65559.1 - 9e-14 51.8 0.0 2.8e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY65559.1 - 4.3e-10 39.6 0.0 1e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KEY65559.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T2SSE PF00437.20 KEY65559.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KEY65559.1 - 0.09 13.0 0.1 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.29 KEY65560.1 - 2.8e-31 107.2 1.5 2.6e-06 27.1 0.0 7.4 7 0 0 7 7 7 6 KH domain FAD_binding_4 PF01565.23 KEY65561.1 - 6.6e-25 87.5 1.7 1.4e-24 86.4 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY65561.1 - 7.1e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Pribosyltran PF00156.27 KEY65562.1 - 1.3e-14 54.1 0.9 1.8e-14 53.5 0.9 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Hydrolase PF00702.26 KEY65564.1 - 1.3e-12 48.5 0.0 1e-11 45.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEY65564.1 - 3.7e-12 46.7 0.0 5.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY65564.1 - 0.0025 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KEY65564.1 - 0.0069 16.8 0.0 0.0088 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Med21 PF11221.8 KEY65565.1 - 1.1e-42 145.6 7.2 1.3e-42 145.5 7.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 KEY65565.1 - 0.0014 18.0 8.5 0.041 13.2 0.1 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KEY65565.1 - 0.0031 17.6 0.2 0.0031 17.6 0.2 2.8 2 1 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 DUF4455 PF14643.6 KEY65565.1 - 0.0038 15.9 3.7 0.0038 15.9 3.7 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4455) Spore_III_AB PF09548.10 KEY65565.1 - 0.0099 16.0 1.9 0.013 15.7 1.9 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DUF4407 PF14362.6 KEY65565.1 - 0.038 13.4 1.2 0.044 13.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phi-29_GP16_7 PF06720.11 KEY65565.1 - 0.078 12.8 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 APG6_N PF17675.1 KEY65565.1 - 0.61 10.6 11.6 1.7 9.1 11.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Sec62 PF03839.16 KEY65566.1 - 1.6e-70 237.0 2.3 2.8e-70 236.2 2.3 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 PrgI PF12666.7 KEY65566.1 - 2.4 8.9 5.4 0.79 10.5 2.1 1.9 1 1 1 2 2 2 0 PrgI family protein FAM222A PF15258.6 KEY65566.1 - 5.3 6.0 16.5 9.3 5.2 16.5 1.3 1 0 0 1 1 1 0 Protein family of FAM222A IER PF05760.12 KEY65566.1 - 8.7 6.5 8.6 9.4 6.4 1.5 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) Ribonuclease_T2 PF00445.18 KEY65567.1 - 7.2e-36 124.1 0.1 1e-35 123.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Acetyltransf_10 PF13673.7 KEY65568.1 - 3.8e-09 36.5 0.3 6.4e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY65568.1 - 1e-07 32.2 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY65568.1 - 1.1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY65568.1 - 1.3e-06 28.3 0.1 2.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEY65568.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KEY65568.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RC-P840_PscD PF10657.9 KEY65568.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD PLDc PF00614.22 KEY65569.1 - 1.1e-15 57.0 2.9 3.2e-08 33.4 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KEY65569.1 - 1.7e-15 57.1 0.0 7.4e-06 25.9 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain Regulator_TrmB PF11495.8 KEY65569.1 - 0.096 11.8 0.4 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Thioredoxin PF00085.20 KEY65570.1 - 1.3e-39 134.3 0.0 3.7e-24 84.7 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KEY65570.1 - 2.1e-10 40.8 0.0 1.3e-05 25.2 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEY65570.1 - 2.5e-07 30.9 0.1 0.021 15.1 0.0 4.4 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KEY65570.1 - 4.3e-05 23.9 2.2 0.12 12.8 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KEY65570.1 - 0.00074 19.3 0.3 0.59 9.9 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_7 PF13899.6 KEY65570.1 - 0.0011 19.2 0.5 0.095 12.9 0.0 2.8 3 0 0 3 3 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KEY65570.1 - 0.0054 16.6 2.2 0.045 13.7 0.0 3.3 4 0 0 4 4 4 1 AhpC/TSA family OST3_OST6 PF04756.13 KEY65570.1 - 0.014 14.7 0.0 2.2 7.5 0.0 2.6 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family HyaE PF07449.11 KEY65570.1 - 0.046 13.7 0.0 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KEY65570.1 - 0.072 12.9 2.9 0.59 9.9 0.0 3.0 2 1 0 3 3 3 0 F plasmid transfer operon protein zf-FPG_IleRS PF06827.14 KEY65570.1 - 1.2 9.1 5.8 6.9 6.6 0.5 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UBN_AB PF14075.6 KEY65570.1 - 8.8 6.0 9.0 0.22 11.2 1.3 1.9 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Tyr-DNA_phospho PF06087.12 KEY65571.1 - 2.8e-157 524.0 0.0 3.2e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KEY65571.1 - 0.014 15.3 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain MatE PF01554.18 KEY65572.1 - 2.3e-53 180.1 29.5 8.8e-32 110.0 10.3 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KEY65572.1 - 0.00063 19.8 10.9 0.00063 19.8 10.9 3.6 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Zn_clus PF00172.18 KEY65574.1 - 5.9e-08 32.7 8.2 1.1e-07 31.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDH-cyt PF16010.5 KEY65576.1 - 6.7e-17 61.8 0.1 1.2e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KEY65576.1 - 2.9e-06 27.5 2.9 8.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.9 KEY65576.1 - 0.00011 21.9 0.2 0.00011 21.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF3784 PF12650.7 KEY65576.1 - 0.96 9.7 7.6 1.7 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) ATP_sub_h PF10775.9 KEY65577.1 - 5e-25 87.3 0.2 7.2e-25 86.8 0.2 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 KEY65578.1 - 1.2e-69 234.7 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65578.1 - 8.8e-32 110.4 0.0 1.1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KEY65578.1 - 2.8e-13 50.3 0.2 2.8e-13 50.3 0.2 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 KEY65578.1 - 1.6e-10 41.2 0.0 3.9e-08 33.5 0.0 2.6 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KEY65578.1 - 2.5e-09 36.9 0.1 6.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEY65578.1 - 0.0015 17.5 0.1 0.0032 16.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY65578.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KEY65578.1 - 0.025 14.2 0.4 2.1 7.9 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KEY65578.1 - 0.071 12.7 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KEY65578.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUZ PF12752.7 KEY65579.1 - 4.8e-06 27.2 4.0 4.8e-06 27.2 4.0 3.5 2 1 1 3 3 3 1 SUZ domain Lipase_chap PF03280.14 KEY65579.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.6 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein Fe_hyd_lg_C PF02906.14 KEY65580.1 - 9.9e-50 169.5 0.0 2.7e-49 168.1 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain AreA_N PF07573.11 KEY65580.1 - 0.024 15.3 0.1 0.061 14.0 0.1 1.6 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus DAHP_synth_1 PF00793.20 KEY65583.1 - 3e-98 328.1 0.0 4.2e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-H2C2_2 PF13465.6 KEY65583.1 - 1.3e-05 25.4 1.3 1.3e-05 25.4 1.3 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KEY65583.1 - 2.4e-05 24.5 0.5 2.4e-05 24.5 0.5 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KEY65583.1 - 2.8e-05 24.0 0.7 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KEY65583.1 - 0.00025 21.6 3.5 0.61 10.7 0.0 3.0 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KEY65583.1 - 0.0013 19.4 4.7 0.0099 16.6 0.4 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger Sina PF03145.16 KEY65583.1 - 8.3 6.3 6.8 11 5.9 1.7 2.4 1 1 1 2 2 2 0 Seven in absentia protein family Fungal_trans_2 PF11951.8 KEY65584.1 - 8e-39 133.5 0.3 4.8e-38 131.0 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4632 PF15451.6 KEY65584.1 - 0.071 13.2 1.3 2.6 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Pro_isomerase PF00160.21 KEY65585.1 - 7.9e-50 169.2 0.1 2.1e-49 167.8 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KEY65585.1 - 3.7e-12 46.5 0.0 7.8e-05 23.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65585.1 - 2.5e-07 30.9 0.0 0.00025 21.3 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY65585.1 - 0.0046 16.0 0.3 0.22 10.5 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Far-17a_AIG1 PF04750.14 KEY65586.1 - 5.1e-49 166.3 13.8 5.8e-49 166.2 13.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DHHC PF01529.20 KEY65586.1 - 9.2 6.4 8.1 9.7 6.3 0.6 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase SLD5_C PF16922.5 KEY65587.1 - 7.3e-12 45.3 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KEY65587.1 - 1.9e-07 31.5 0.3 5.5e-07 30.0 0.2 1.8 2 0 0 2 2 2 1 GINS complex protein DUF896 PF05979.12 KEY65587.1 - 0.018 14.9 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Apolipoprotein PF01442.18 KEY65588.1 - 0.089 12.7 0.4 0.21 11.4 0.4 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ANAPC4_WD40 PF12894.7 KEY65589.1 - 5.8e-08 32.9 0.0 0.055 13.8 0.0 5.0 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY65589.1 - 5.3e-07 30.2 0.3 0.17 12.8 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Indigoidine_A PF04227.12 KEY65590.1 - 6.3e-110 367.1 1.5 9.7e-110 366.5 1.5 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KEY65590.1 - 3.4e-23 82.4 0.0 2.4e-14 53.3 0.0 3.1 3 1 0 3 3 3 2 pfkB family carbohydrate kinase HTH_DeoR PF08220.12 KEY65590.1 - 0.068 12.9 1.0 1.1 9.1 0.4 2.9 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain adh_short PF00106.25 KEY65592.1 - 4.5e-37 127.4 0.1 6.3e-37 126.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY65592.1 - 9.1e-28 97.4 0.0 1.3e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY65592.1 - 3.1e-08 33.7 1.2 8e-07 29.1 1.2 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY65592.1 - 1.3e-05 24.8 0.1 2.7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY65592.1 - 0.037 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEY65592.1 - 0.042 12.8 0.0 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.19 KEY65593.1 - 1e-73 248.6 0.0 1.3e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEY65593.1 - 1.6e-29 103.0 0.0 2.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KEY65593.1 - 6.2e-05 22.4 0.0 0.00029 20.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY65593.1 - 0.00021 20.1 0.1 0.00033 19.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KEY65593.1 - 0.00041 20.9 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY65593.1 - 0.00047 20.3 0.1 0.0013 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY65593.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KEY65593.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KEY65593.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEY65593.1 - 0.019 14.2 0.0 0.078 12.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY65593.1 - 0.029 13.4 0.0 0.066 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KEY65593.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KEY65593.1 - 0.045 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.6 KEY65593.1 - 0.084 13.4 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.17 KEY65593.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KEY65593.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KEY65593.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box PF00646.33 KEY65594.1 - 0.00013 21.8 1.1 0.00025 20.8 1.1 1.5 1 0 0 1 1 1 1 F-box domain IMUP PF15761.5 KEY65594.1 - 0.35 11.6 8.6 1.4 9.6 7.5 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 KEY65594.1 - 2.5 7.6 8.0 5.4 6.6 8.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KEY65594.1 - 7 4.6 4.5 9.5 4.2 4.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FOXP-CC PF16159.5 KEY65595.1 - 0.18 12.4 1.7 0.33 11.6 0.8 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KEY65595.1 - 0.19 12.3 0.2 0.41 11.2 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1682 PF07946.14 KEY65595.1 - 2.1 7.5 4.8 2.8 7.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAR2 PF05282.11 KEY65596.1 - 5.7e-43 147.7 0.0 1.2e-42 146.6 0.0 1.5 1 1 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.19 KEY65597.1 - 2e-33 115.5 0.1 2.2e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L32e PF01655.18 KEY65598.1 - 1.1e-49 167.3 0.2 1.1e-49 167.3 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L32 SH3_1 PF00018.28 KEY65599.1 - 0.0001 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY65599.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ELFV_dehydrog PF00208.21 KEY65600.1 - 5e-64 216.3 0.0 8.3e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KEY65600.1 - 1.2e-17 62.9 0.0 6.2e-13 47.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KEY65600.1 - 0.0034 17.3 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain OSTMP1 PF09777.9 KEY65601.1 - 0.19 11.1 0.1 0.26 10.7 0.1 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor CLLAC PF15675.5 KEY65601.1 - 0.69 9.5 4.8 0.42 10.2 1.9 1.9 2 0 0 2 2 2 0 CLLAC-motif containing domain Tom22 PF04281.13 KEY65602.1 - 1.4e-47 161.0 0.0 1.7e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4581 PF15167.6 KEY65602.1 - 0.24 11.5 1.9 0.36 11.0 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4581) Dynamin_N PF00350.23 KEY65603.1 - 2.3e-19 70.1 1.5 2.9e-19 69.8 0.1 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEY65603.1 - 4.8e-11 42.7 0.1 1.1e-09 38.4 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY65603.1 - 3e-06 26.9 1.3 5.9e-05 22.7 1.3 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY65603.1 - 0.0089 15.9 0.2 2.3 8.1 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 KEY65603.1 - 0.021 15.0 0.1 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KEY65603.1 - 0.026 14.1 0.5 0.24 11.0 0.5 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KEY65603.1 - 0.031 14.8 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEY65603.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TK PF00265.18 KEY65603.1 - 0.086 12.7 1.3 0.56 10.1 0.1 2.3 1 1 1 2 2 2 0 Thymidine kinase Prominin PF05478.11 KEY65603.1 - 0.11 10.5 1.6 0.2 9.6 1.6 1.4 1 0 0 1 1 1 0 Prominin Sigma54_activat PF00158.26 KEY65603.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PRKG1_interact PF15898.5 KEY65603.1 - 1.3 10.0 4.8 16 6.5 2.2 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Snf7 PF03357.21 KEY65604.1 - 2.2e-34 118.6 20.1 2.2e-34 118.6 20.1 1.4 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 KEY65604.1 - 0.25 11.3 7.5 0.38 10.7 7.5 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DDE_Tnp_1 PF01609.21 KEY65604.1 - 0.55 9.8 2.7 0.8 9.3 2.7 1.2 1 0 0 1 1 1 0 Transposase DDE domain PspA_IM30 PF04012.12 KEY65604.1 - 1.2 8.6 16.0 2.4 7.7 5.7 2.2 1 1 1 2 2 2 0 PspA/IM30 family PP2C PF00481.21 KEY65605.1 - 1.1e-59 202.2 0.2 7.9e-49 166.6 0.4 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C Cofilin_ADF PF00241.20 KEY65606.1 - 0.0014 18.4 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Zn_clus PF00172.18 KEY65607.1 - 3.5e-07 30.2 11.9 5.5e-07 29.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.16 KEY65608.1 - 1.6e-17 63.2 0.0 3.3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KEY65608.1 - 0.00021 21.4 2.3 0.004 17.3 2.3 2.4 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 KEY65609.1 - 2.4e-45 153.7 0.2 2.4e-45 153.7 0.2 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KEY65609.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 WH1 domain PS-DH PF14765.6 KEY65609.1 - 0.058 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase zf-TFIIIC PF12660.7 KEY65611.1 - 0.038 13.9 1.2 0.065 13.2 1.2 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex FolB PF02152.18 KEY65612.1 - 3.2e-19 69.5 0.0 3.4e-16 59.8 0.0 2.6 2 1 0 2 2 2 2 Dihydroneopterin aldolase DUF3605 PF12239.8 KEY65613.1 - 3.8e-56 189.7 0.1 4.6e-56 189.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 KEY65614.1 - 2e-191 636.1 0.0 2.3e-191 635.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 KEY65614.1 - 0.24 10.2 2.7 1.5 7.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) NUDE_C PF04880.13 KEY65616.1 - 9.7 6.6 12.6 17 5.8 12.6 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3336 PF11815.8 KEY65618.1 - 1.5e-36 125.1 0.1 1.3e-35 122.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEY65618.1 - 1.7e-12 47.9 0.2 4e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Leo1 PF04004.13 KEY65619.1 - 3.9e-32 111.4 2.2 4.2e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein RNA_polI_A34 PF08208.11 KEY65619.1 - 6.9 6.7 13.0 2.5 8.2 7.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Mob1_phocein PF03637.17 KEY65620.1 - 7e-42 143.3 0.1 2e-41 141.8 0.1 1.7 1 1 0 1 1 1 1 Mob1/phocein family Fungal_trans PF04082.18 KEY65621.1 - 6.8e-09 35.1 0.0 1.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65621.1 - 1.2e-06 28.5 9.3 2.4e-06 27.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin_4 PF13462.6 KEY65623.1 - 3.3e-09 37.1 0.0 6.8e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KEY65623.1 - 0.0073 16.1 2.2 0.4 10.4 0.1 2.8 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Phage_TAC_6 PF09550.10 KEY65623.1 - 0.034 14.6 0.1 0.074 13.5 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC p450 PF00067.22 KEY65624.1 - 5.9e-13 48.4 0.0 8.3e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 PRTase_3 PF15610.6 KEY65624.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like YwcE PF17368.2 KEY65624.1 - 0.1 13.2 0.2 2.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE Zip PF02535.22 KEY65625.1 - 1.8e-51 175.4 2.4 2.7e-51 174.8 2.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter 2OG-FeII_Oxy PF03171.20 KEY65626.1 - 0.0035 17.8 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 KEY65627.1 - 7.7e-45 153.0 0.2 7.7e-45 153.0 0.2 1.8 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KEY65627.1 - 0.017 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Frataxin_Cyay PF01491.16 KEY65627.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Frataxin-like domain WD40 PF00400.32 KEY65628.1 - 2.6e-09 37.5 6.1 0.028 15.3 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65628.1 - 0.051 13.9 0.0 28 5.1 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KEY65628.1 - 0.09 11.5 0.0 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Mito_carr PF00153.27 KEY65629.1 - 1.4e-65 217.2 1.9 1.2e-21 76.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY65629.1 - 0.1 11.7 0.5 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease F-box-like PF12937.7 KEY65630.1 - 3e-10 39.8 0.0 6.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY65630.1 - 0.0035 17.2 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KEY65630.1 - 0.035 14.2 0.3 0.073 13.1 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain PRiA4_ORF3 PF07929.11 KEY65630.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein DdrB PF12747.7 KEY65630.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 DdrB-like protein TPR_2 PF07719.17 KEY65630.1 - 0.23 11.7 0.8 1.5 9.1 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1056 PF06341.11 KEY65632.1 - 0.014 15.7 2.4 0.014 15.7 2.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) HemY_N PF07219.13 KEY65632.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.9 3 1 1 4 4 4 0 HemY protein N-terminus MBOAT PF03062.19 KEY65633.1 - 6.3e-46 157.3 13.8 6.3e-46 157.3 13.8 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Glyco_transf_4 PF13439.6 KEY65634.1 - 0.00026 21.0 0.1 0.00049 20.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEY65634.1 - 0.0012 19.3 0.8 0.0031 18.0 0.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Epimerase PF01370.21 KEY65635.1 - 6.9e-12 45.3 0.0 1.5e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY65635.1 - 6.3e-07 29.1 0.0 9.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 KEY65635.1 - 4.2e-06 26.8 11.6 9.8e-06 25.6 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KEY65635.1 - 0.00094 19.1 0.1 0.0025 17.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY65635.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Vps5 PF09325.10 KEY65636.1 - 0.00086 18.9 1.7 0.0012 18.4 1.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF4201 PF13870.6 KEY65636.1 - 0.0074 16.0 3.6 0.015 15.0 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HSP70 PF00012.20 KEY65636.1 - 0.38 8.9 1.6 0.46 8.6 1.6 1.1 1 0 0 1 1 1 0 Hsp70 protein GrpE PF01025.19 KEY65636.1 - 0.51 10.0 5.6 0.88 9.2 5.6 1.3 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.6 KEY65636.1 - 3 7.1 12.5 1.3 8.3 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KEY65638.1 - 0.068 13.1 0.5 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 F-box-like Glycophorin_A PF01102.18 KEY65640.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A 5_nucleotid_C PF02872.18 KEY65641.1 - 6.8e-38 130.4 0.0 1.2e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KEY65641.1 - 7.4e-07 29.9 0.1 1.2e-06 29.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KEY65642.1 - 3.1e-23 82.3 47.9 7e-19 68.0 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY65642.1 - 1.6e-13 50.3 15.7 5.7e-13 48.5 15.3 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Glycos_transf_1 PF00534.20 KEY65644.1 - 3.1e-36 124.5 0.0 4.7e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY65644.1 - 1.4e-26 93.5 0.0 2.4e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEY65644.1 - 2e-16 60.8 0.1 3.8e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEY65644.1 - 1.5e-14 54.4 0.0 6.4e-14 52.3 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEY65644.1 - 1e-09 38.6 0.0 2.7e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF485 PF04341.12 KEY65644.1 - 0.045 13.7 0.7 0.094 12.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UDPG_MGDP_dh_N PF03721.14 KEY65645.1 - 3.1e-48 163.8 0.0 1e-30 106.7 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KEY65645.1 - 5.9e-32 109.7 0.0 1.3e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KEY65645.1 - 3e-23 82.2 0.0 3.2e-17 62.9 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KEY65645.1 - 0.031 14.4 0.0 0.57 10.3 0.0 2.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KEY65645.1 - 0.036 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KEY65645.1 - 0.046 13.7 0.1 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GLEYA PF10528.9 KEY65647.1 - 5.6e-16 58.7 0.0 1.2e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 GLEYA domain FG-GAP PF01839.23 KEY65647.1 - 0.00036 20.6 15.6 0.00037 20.6 1.4 3.8 1 1 2 3 3 3 2 FG-GAP repeat VanY PF02557.17 KEY65648.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF3636 PF12331.8 KEY65649.1 - 2.6e-35 121.4 0.8 6.3e-35 120.2 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KEY65649.1 - 0.013 14.0 0.0 0.61 8.5 0.0 2.4 2 1 0 2 2 2 0 DNA damage checkpoint protein DUF4094 PF13334.6 KEY65649.1 - 0.27 11.7 0.1 0.27 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TMF_TATA_bd PF12325.8 KEY65649.1 - 0.73 10.1 9.7 0.1 12.8 5.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Striatin PF08232.12 KEY65649.1 - 0.81 10.3 5.9 1.8 9.1 5.9 1.5 1 0 0 1 1 1 0 Striatin family DUF3128 PF11326.8 KEY65650.1 - 3.2e-27 94.7 3.5 3.2e-27 94.7 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 KEY65650.1 - 1.3 7.7 5.2 1.3 7.7 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA12 PF10443.9 KEY65651.1 - 6.7e-158 526.1 1.0 8.1e-158 525.8 0.1 1.6 2 0 0 2 2 2 1 RNA12 protein ATPase_2 PF01637.18 KEY65651.1 - 1.5e-05 25.0 0.0 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KEY65651.1 - 4.9e-05 23.1 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KEY65651.1 - 0.011 16.1 0.5 0.11 12.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF2487 PF10673.9 KEY65651.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) CENP-C_C PF11699.8 KEY65652.1 - 6.6e-34 116.0 0.1 1.1e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KEY65652.1 - 5.7e-07 29.1 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEY65652.1 - 0.076 12.7 0.4 0.33 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KEY65652.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Rrn6 PF10214.9 KEY65652.1 - 0.48 8.8 1.7 0.77 8.2 1.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DMRL_synthase PF00885.19 KEY65654.1 - 2.3e-57 192.8 0.1 2.8e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.6 KEY65655.1 - 4.3e-12 46.0 0.0 8.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KEY65655.1 - 2.1e-09 37.1 0.0 6.7e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KEY65655.1 - 1.3e-07 32.1 0.0 2.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRP PF06011.12 KEY65656.1 - 3.6e-40 138.0 24.4 1.3e-38 132.9 24.4 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEY65656.1 - 1.6e-25 90.1 0.0 2.4e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 ML-like domain RNase_T PF00929.24 KEY65657.1 - 1.9e-07 31.8 0.0 9.8e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Exonuclease SHE3 PF17078.5 KEY65658.1 - 5e-05 23.1 0.5 6.1e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 KEY65658.1 - 0.00059 20.4 6.0 0.00094 19.7 6.0 1.3 1 0 0 1 1 1 1 Fez1 ERM PF00769.19 KEY65658.1 - 0.0006 19.7 8.0 0.0008 19.3 8.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SlyX PF04102.12 KEY65658.1 - 0.001 19.6 1.5 2.8 8.6 0.6 3.4 3 0 0 3 3 3 1 SlyX GIT_CC PF16559.5 KEY65658.1 - 0.0021 17.9 2.9 0.0094 15.8 3.1 2.0 2 0 0 2 2 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF812 PF05667.11 KEY65658.1 - 0.0024 16.9 2.4 0.0037 16.2 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Leu_zip PF15294.6 KEY65658.1 - 0.0056 16.2 2.6 0.007 15.9 2.6 1.2 1 0 0 1 1 1 1 Leucine zipper DUF4407 PF14362.6 KEY65658.1 - 0.012 15.0 1.3 0.014 14.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KEY65658.1 - 0.013 14.1 1.1 0.017 13.8 1.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KEY65658.1 - 0.014 15.1 5.6 0.11 12.3 2.9 2.8 1 1 2 3 3 3 0 Septum formation initiator I_LWEQ PF01608.17 KEY65658.1 - 0.014 15.6 4.0 0.025 14.8 4.0 1.3 1 0 0 1 1 1 0 I/LWEQ domain ZapB PF06005.12 KEY65658.1 - 0.023 15.1 4.3 0.023 15.1 4.3 3.2 2 1 1 3 3 3 0 Cell division protein ZapB DUF3450 PF11932.8 KEY65658.1 - 0.027 13.8 1.6 0.04 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.13 KEY65658.1 - 0.03 14.7 10.2 0.63 10.4 6.4 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 KEY65658.1 - 0.034 14.8 3.2 0.16 12.6 3.2 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KEY65658.1 - 0.035 13.0 4.4 0.058 12.3 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KEY65658.1 - 0.037 13.8 1.8 0.077 12.8 1.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 bZIP_2 PF07716.15 KEY65658.1 - 0.038 14.1 4.4 0.048 13.7 1.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Golgin_A5 PF09787.9 KEY65658.1 - 0.058 12.8 8.5 0.11 11.9 8.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 ADIP PF11559.8 KEY65658.1 - 0.072 13.2 6.4 0.2 11.8 6.0 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KEY65658.1 - 0.087 12.9 8.2 1 9.4 5.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG5 PF10392.9 KEY65658.1 - 0.095 12.9 1.2 0.25 11.5 1.2 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Sec34 PF04136.15 KEY65658.1 - 0.096 12.6 3.1 0.18 11.7 3.1 1.4 1 0 0 1 1 1 0 Sec34-like family DUF4200 PF13863.6 KEY65658.1 - 0.12 12.8 4.6 0.18 12.2 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KEY65658.1 - 0.13 12.8 12.2 0.62 10.6 12.2 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 KEY65658.1 - 0.14 12.3 9.3 0.24 11.6 9.3 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Prp19 PF08606.11 KEY65658.1 - 0.16 12.0 2.5 7.5 6.6 0.0 2.8 2 1 0 2 2 2 0 Prp19/Pso4-like Snapin_Pallidin PF14712.6 KEY65658.1 - 0.18 12.3 2.8 0.88 10.0 2.8 2.2 1 1 0 1 1 1 0 Snapin/Pallidin Jnk-SapK_ap_N PF09744.9 KEY65658.1 - 0.18 12.0 11.9 0.84 9.8 11.9 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 KEY65658.1 - 0.22 12.1 8.1 3.2 8.4 6.4 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Swi5 PF07061.11 KEY65658.1 - 0.25 11.4 4.9 1 9.5 1.7 2.9 1 1 1 2 2 2 0 Swi5 Nnf1 PF03980.14 KEY65658.1 - 0.26 11.7 7.1 0.34 11.3 5.4 2.1 2 1 0 2 2 2 0 Nnf1 TSC22 PF01166.18 KEY65658.1 - 0.42 11.0 3.1 0.56 10.5 0.5 2.5 3 0 0 3 3 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 KEY65658.1 - 0.54 10.3 7.3 0.77 9.8 7.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KEY65658.1 - 0.66 10.5 5.1 12 6.4 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 KEY65658.1 - 0.8 9.8 12.5 4.8 7.3 10.6 3.0 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 KEY65658.1 - 1.1 9.7 7.7 3.9 7.9 7.4 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 KEY65658.1 - 1.1 9.5 9.3 27 5.1 9.2 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.6 KEY65658.1 - 1.2 9.3 9.6 2.9 8.0 6.4 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 KEY65658.1 - 1.2 9.3 7.3 0.32 11.1 2.2 2.5 3 1 0 3 3 2 0 bZIP transcription factor PRKG1_interact PF15898.5 KEY65658.1 - 1.2 10.0 8.9 3.8 8.5 5.3 2.4 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KEY65658.1 - 1.7 9.1 8.9 1.6 9.1 1.7 3.7 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 KEY65658.1 - 1.8 8.9 6.2 2.3 8.6 3.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KfrA_N PF11740.8 KEY65658.1 - 4.3 8.0 11.6 2.2 9.0 2.2 3.3 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term SET PF00856.28 KEY65659.1 - 5.6e-09 36.6 0.0 3.3e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KEY65659.1 - 2.4e-08 33.9 11.4 4.4e-08 33.1 11.4 1.5 1 0 0 1 1 1 1 MYND finger SIL1 PF16782.5 KEY65660.1 - 2.5e-12 46.6 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Glutaredoxin PF00462.24 KEY65661.1 - 1.7e-13 50.5 0.3 5.3e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 KEY65661.1 - 0.0073 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.18 KEY65662.1 - 1.2e-07 31.8 12.0 1.9e-07 31.1 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pheromone PF08015.11 KEY65662.1 - 0.038 15.0 0.1 0.038 15.0 0.1 3.3 3 1 0 3 3 3 0 Fungal mating-type pheromone SR-25 PF10500.9 KEY65662.1 - 2.5 7.7 15.8 3.8 7.1 15.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_A12 PF04651.13 KEY65662.1 - 5.1 7.1 5.7 7.8 6.5 5.7 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein PAP1 PF08601.10 KEY65662.1 - 9.2 5.9 11.7 13 5.3 11.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 HLH PF00010.26 KEY65663.1 - 2e-12 46.9 1.4 5.5e-12 45.5 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 KEY65663.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 KEY65663.1 - 0.031 14.5 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4776 PF16003.5 KEY65663.1 - 0.079 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DivIC PF04977.15 KEY65663.1 - 0.083 12.7 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KEY65663.1 - 0.1 13.3 0.3 0.25 12.0 0.2 1.7 1 1 0 1 1 1 0 Initiation control protein YabA KinB_sensor PF16767.5 KEY65663.1 - 0.47 10.9 2.5 0.96 9.9 2.5 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB SlyX PF04102.12 KEY65663.1 - 8.9 7.0 8.4 25 5.6 0.2 3.6 2 1 1 3 3 3 0 SlyX TPR_1 PF00515.28 KEY65666.1 - 1.3e-26 91.2 2.0 2e-07 30.5 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65666.1 - 9.2e-25 84.7 4.1 6.1e-07 29.1 0.1 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KEY65666.1 - 6.7e-21 73.7 4.8 3.8e-08 32.9 0.1 5.4 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KEY65666.1 - 7.1e-19 68.2 6.3 5.8e-07 30.1 1.9 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65666.1 - 9.7e-18 63.4 4.8 1.1e-05 25.8 0.1 6.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY65666.1 - 9.4e-16 56.6 2.7 2.9e-06 27.0 0.0 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY65666.1 - 2.6e-14 52.5 4.8 0.0057 16.9 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65666.1 - 3.7e-14 51.6 2.6 0.0053 16.7 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY65666.1 - 1.8e-11 44.3 15.9 0.0025 18.3 0.9 5.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KEY65666.1 - 2e-09 37.6 3.3 0.0082 16.5 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEY65666.1 - 3.6e-09 36.7 1.8 0.77 10.5 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65666.1 - 6.5e-09 36.0 10.0 0.0077 16.5 2.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEY65666.1 - 3.3e-08 33.6 4.0 0.0036 17.4 0.5 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY65666.1 - 7.5e-05 22.9 4.3 0.11 12.7 0.5 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KEY65666.1 - 8e-05 22.0 5.8 0.085 12.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 KEY65666.1 - 0.0032 17.4 1.2 9.1 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KEY65666.1 - 0.041 14.0 2.6 16 5.6 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.9 KEY65666.1 - 0.066 12.2 0.1 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.6 KEY65666.1 - 0.077 12.9 0.4 0.077 12.9 0.4 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1641 PF07849.11 KEY65666.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Brix PF04427.18 KEY65667.1 - 3.9e-42 144.6 0.2 5e-42 144.2 0.2 1.1 1 0 0 1 1 1 1 Brix domain Zn_clus PF00172.18 KEY65668.1 - 6.5e-08 32.6 10.4 1e-07 31.9 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY65668.1 - 0.00034 19.6 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3040 PF11239.8 KEY65668.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Cys_Met_Meta_PP PF01053.20 KEY65669.1 - 6.6e-137 456.1 0.0 7.4e-137 455.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEY65669.1 - 2.1e-06 27.0 0.1 4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEY65669.1 - 1.5e-05 24.4 0.1 2.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEY65669.1 - 0.00036 20.0 0.4 0.00054 19.4 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family 2-Hacid_dh PF00389.30 KEY65669.1 - 0.0099 15.5 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GDC-P PF02347.16 KEY65669.1 - 0.031 13.1 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein F-box-like PF12937.7 KEY65670.1 - 0.085 12.8 0.3 0.56 10.1 0.1 2.4 2 0 0 2 2 2 0 F-box-like Amidoligase_2 PF12224.8 KEY65672.1 - 9.4e-17 61.5 0.0 9e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Putative amidoligase enzyme RNA_pol_Rpb1_5 PF04998.17 KEY65673.1 - 1.4e-78 264.0 0.3 2.2e-78 263.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KEY65673.1 - 6e-77 259.0 0.0 1.1e-76 258.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KEY65673.1 - 1.3e-69 233.7 0.0 3.2e-69 232.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KEY65673.1 - 9.6e-39 132.8 0.0 1.9e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEY65673.1 - 6.9e-30 103.2 0.1 1.9e-29 101.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 zf-ribbon_3 PF13248.6 KEY65673.1 - 0.14 11.6 1.5 4.8 6.7 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RPN2_C PF18004.1 KEY65674.1 - 2.3e-60 203.1 2.3 2.3e-60 203.1 2.3 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KEY65674.1 - 7.6e-42 139.7 18.3 1.1e-08 35.0 0.0 8.0 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KEY65674.1 - 2.2e-22 79.2 0.2 3.8e-14 52.8 0.0 5.5 4 1 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KEY65674.1 - 1.3e-05 25.1 0.0 3.3 8.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KEY65674.1 - 4.6e-05 23.8 2.0 0.02 15.4 0.0 5.1 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 KEY65674.1 - 0.006 16.6 0.1 3.2 7.8 0.0 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Oxidored_molyb PF00174.19 KEY65675.1 - 1.8e-54 184.0 0.0 2.6e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KEY65675.1 - 7e-31 107.1 0.2 1.2e-30 106.3 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KEY65675.1 - 2.2e-11 43.7 0.1 4e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM100 PF16311.5 KEY65677.1 - 0.095 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 DUF943 PF06092.12 KEY65677.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) CTP_transf_like PF01467.26 KEY65678.1 - 9.3e-07 29.1 0.1 2.4e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF3506 PF12014.8 KEY65679.1 - 6.3e-58 194.7 0.0 2.3e-57 192.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KEY65679.1 - 2.5e-05 24.1 0.2 4.8e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY65679.1 - 0.0042 16.9 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain Cupin_2 PF07883.11 KEY65680.1 - 3.4e-10 39.5 0.1 5.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEY65680.1 - 0.00077 19.1 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 KEY65680.1 - 0.0013 18.9 0.0 0.0018 18.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_1 PF00190.22 KEY65680.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 KEY65680.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KEY65680.1 - 0.046 13.6 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Abhydrolase_1 PF00561.20 KEY65681.1 - 0.00089 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-RING_2 PF13639.6 KEY65682.1 - 0.00035 20.8 0.8 0.00035 20.8 0.8 2.7 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 KEY65682.1 - 0.0071 16.2 7.2 0.0096 15.8 6.0 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEY65682.1 - 0.051 13.4 1.0 0.051 13.4 1.0 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY65682.1 - 0.37 10.8 10.2 0.046 13.7 4.8 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY65682.1 - 5 7.2 9.7 2.1 8.4 4.5 2.8 2 1 1 3 3 3 0 RING-type zinc-finger DUF1769 PF08588.10 KEY65683.1 - 3e-27 94.6 0.7 5.4e-27 93.8 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Adeno_E3_CR2 PF02439.15 KEY65684.1 - 0.0012 18.5 0.8 0.002 17.9 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KEY65684.1 - 0.0013 19.0 0.0 0.0038 17.4 0.0 1.7 2 0 0 2 2 2 1 Glycophorin A Syndecan PF01034.20 KEY65684.1 - 0.0022 17.9 1.3 0.0037 17.1 1.3 1.3 1 0 0 1 1 1 1 Syndecan domain TMEM51 PF15345.6 KEY65684.1 - 0.009 15.9 0.8 0.11 12.3 0.2 2.1 1 1 1 2 2 2 1 Transmembrane protein 51 RCR PF12273.8 KEY65684.1 - 0.021 15.5 0.0 0.041 14.5 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.12 KEY65684.1 - 0.022 15.2 0.5 0.044 14.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.16 KEY65684.1 - 0.045 12.5 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 KEY65684.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 KEY65684.1 - 0.15 11.9 0.1 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.12 KEY65684.1 - 0.2 11.5 0.3 0.33 10.8 0.3 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4690 PF15756.5 KEY65684.1 - 0.39 11.3 3.6 0.25 11.9 0.8 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage SKG6 PF08693.10 KEY65684.1 - 2 7.9 7.7 3.2 7.2 7.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 KEY65685.1 - 6.5e-28 97.7 29.2 6.5e-28 97.7 29.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Polysacc_synt_4 PF04669.13 KEY65686.1 - 1.3e-22 80.3 0.9 4.5e-21 75.3 0.9 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 KEY65686.1 - 0.0093 15.6 1.5 0.019 14.7 1.5 1.5 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain DUF2491 PF10679.9 KEY65686.1 - 0.055 12.7 0.8 0.075 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Peroxin-22 PF12827.7 KEY65686.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family ABC_membrane PF00664.23 KEY65687.1 - 3.8e-77 259.6 14.9 4.1e-40 138.2 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY65687.1 - 4e-61 205.5 0.0 3.1e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY65687.1 - 1.8e-14 53.7 0.1 1.3e-05 24.8 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEY65687.1 - 6.4e-14 52.5 0.0 0.015 15.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY65687.1 - 1.1e-08 34.7 0.9 0.0043 16.8 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY65687.1 - 6.8e-08 32.9 0.0 0.009 16.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY65687.1 - 1.4e-07 32.1 0.8 0.00068 20.1 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEY65687.1 - 2.6e-07 30.7 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KEY65687.1 - 4.2e-06 25.8 1.2 0.0002 20.3 0.1 3.5 4 1 0 4 4 4 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KEY65687.1 - 0.00018 22.1 0.2 1.1 9.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KEY65687.1 - 0.00034 20.3 2.2 0.92 9.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KEY65687.1 - 0.00035 20.3 0.1 0.79 9.4 0.0 3.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 KEY65687.1 - 0.0016 18.7 0.2 0.77 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY65687.1 - 0.0016 18.4 0.1 2.4 8.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 KEY65687.1 - 0.0042 17.6 1.5 5.5 7.5 0.0 3.4 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 KEY65687.1 - 0.0057 16.6 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 KEY65687.1 - 0.0058 16.4 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEY65687.1 - 0.0072 16.3 0.0 5.5 7.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KEY65687.1 - 0.0074 16.4 0.2 1.6 8.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KEY65687.1 - 0.0086 15.8 0.2 3.1 7.5 0.0 3.0 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KEY65687.1 - 0.011 16.1 0.0 4.5 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KEY65687.1 - 0.026 14.3 0.1 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KEY65687.1 - 0.042 13.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 KEY65687.1 - 0.045 12.8 0.0 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KEY65687.1 - 0.067 12.7 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KEY65687.1 - 0.074 13.1 0.7 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 KEY65687.1 - 0.35 10.2 2.8 3.3 7.0 0.2 2.7 3 0 0 3 3 3 0 KaiC NUP PF06516.11 KEY65689.1 - 9.5e-126 419.2 0.0 1.1e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.25 KEY65690.1 - 1.3e-42 146.1 0.0 6e-42 143.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65690.1 - 1.8e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEY65690.1 - 0.0003 20.2 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEY65690.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 KEY65690.1 - 0.28 10.1 0.3 2.7 6.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Zn_clus PF00172.18 KEY65693.1 - 6e-07 29.5 7.5 1.2e-06 28.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 KEY65695.1 - 1.9e-55 188.0 0.0 2.2e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KEY65695.1 - 0.066 13.5 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PK PF00224.21 KEY65696.1 - 5e-172 571.5 5.1 7.6e-172 571.0 5.1 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KEY65696.1 - 1.6e-37 128.3 0.0 6.4e-37 126.4 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KEY65696.1 - 0.00024 20.3 1.1 0.00082 18.6 0.9 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KEY65696.1 - 0.02 13.9 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Importin_rep_3 PF18806.1 KEY65696.1 - 0.094 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF1748 PF08520.10 KEY65698.1 - 3.3e-33 113.4 0.1 4e-33 113.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) ZapB PF06005.12 KEY65699.1 - 0.34 11.4 0.0 0.34 11.4 0.0 2.7 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 KEY65699.1 - 0.77 9.6 3.3 0.5 10.2 0.4 2.1 2 0 0 2 2 2 0 Septum formation initiator Cep57_CLD PF14073.6 KEY65699.1 - 1.3 9.0 6.6 0.55 10.2 1.0 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 APG6_N PF17675.1 KEY65699.1 - 1.4 9.4 8.2 0.17 12.4 2.0 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KEY65699.1 - 1.6 8.9 7.9 0.11 12.7 1.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 KEY65699.1 - 1.9 9.1 6.6 4.5 7.9 0.2 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 KEY65699.1 - 2.3 7.0 5.7 0.29 10.0 1.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Tektin PF03148.14 KEY65699.1 - 5.1 5.7 10.0 0.26 10.0 3.4 2.1 3 0 0 3 3 3 0 Tektin family WD40 PF00400.32 KEY65700.1 - 1.9e-12 47.4 9.9 1.6e-05 25.6 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Spt5_N PF11942.8 KEY65701.1 - 4e-19 69.4 7.5 4e-19 69.4 7.5 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KEY65701.1 - 2e-18 66.0 0.0 3.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 KEY65701.1 - 2.2e-16 60.2 26.4 5.2e-16 59.0 15.6 4.8 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KEY65701.1 - 0.00039 20.3 25.6 0.0066 16.4 2.8 5.4 7 0 0 7 7 7 3 KOW motif DUF3912 PF13051.6 KEY65701.1 - 0.051 13.8 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) Peptidase_M56 PF05569.11 KEY65702.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 TFIIA PF03153.13 KEY65702.1 - 3.1 7.7 12.6 3.6 7.5 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KEY65704.1 - 3.8e-14 52.4 0.0 6.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65704.1 - 3e-08 33.6 10.2 6.4e-08 32.6 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 KEY65705.1 - 2.1e-71 239.8 0.8 4e-71 238.8 0.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEY65705.1 - 7.5e-69 232.0 0.0 9.7e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 KEY65706.1 - 5.1e-51 173.6 11.2 6e-51 173.3 11.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.24 KEY65707.1 - 1.5e-51 176.1 0.1 2.4e-51 175.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEY65707.1 - 1.2e-38 131.8 0.0 1.2e-37 128.5 0.0 2.2 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KEY65707.1 - 2.1e-07 30.4 2.1 0.0028 16.8 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KEY65707.1 - 0.00037 20.0 1.9 0.00099 18.6 0.9 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY65707.1 - 0.0013 18.0 0.3 0.0028 16.9 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY65707.1 - 0.013 14.7 0.0 0.055 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEY65707.1 - 0.059 13.3 0.6 0.12 12.3 0.6 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KEY65707.1 - 0.095 11.8 0.1 0.41 9.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEY65707.1 - 0.11 12.8 0.5 0.66 10.2 0.6 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEY65707.1 - 0.12 11.1 0.3 0.19 10.4 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KEY65707.1 - 0.15 11.2 0.6 0.32 10.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Hydrophobin_2 PF06766.11 KEY65708.1 - 2.2e-23 82.0 11.7 2.8e-23 81.6 11.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Aa_trans PF01490.18 KEY65709.1 - 1.8e-74 250.9 24.1 2.2e-74 250.6 24.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Iso_dh PF00180.20 KEY65711.1 - 1.2e-97 327.2 0.0 1.7e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA-synt_His PF13393.6 KEY65712.1 - 1.8e-43 149.0 0.0 2.4e-41 142.0 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KEY65712.1 - 5.2e-10 39.4 0.1 1.6e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Dynactin_p22 PF07426.11 KEY65712.1 - 3.7e-06 26.9 0.0 7.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Dynactin subunit p22 HGTP_anticodon2 PF12745.7 KEY65712.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KEY65712.1 - 0.11 11.5 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) HBD PF18534.1 KEY65712.1 - 0.2 11.8 1.3 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Helical bundle domain Aa_trans PF01490.18 KEY65713.1 - 3.1e-82 276.5 12.5 3.1e-82 276.5 12.5 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 KEY65713.1 - 0.0012 17.8 3.1 0.0012 17.8 3.1 2.5 3 0 0 3 3 3 2 Spore germination protein Abhydrolase_9_N PF15420.6 KEY65713.1 - 0.019 15.0 0.1 0.019 15.0 0.1 3.2 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus DNA_pol_B_exo1 PF03104.19 KEY65713.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Ribosomal_S16 PF00886.19 KEY65714.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KEY65715.1 - 1.5e-15 57.5 0.0 7.2e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 YjeF-related protein N-terminus AA_permease PF00324.21 KEY65716.1 - 1.3e-121 406.5 49.4 1.6e-121 406.3 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY65716.1 - 3.2e-30 105.3 53.9 4.3e-30 104.9 53.9 1.0 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KEY65717.1 - 1e-86 291.6 25.5 1.3e-86 291.3 25.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY65717.1 - 3e-09 36.3 49.1 7.9e-06 25.0 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pirin PF02678.16 KEY65718.1 - 4.3e-25 87.8 1.3 1.9e-24 85.7 1.3 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KEY65718.1 - 5.2e-05 22.9 3.7 0.0073 16.0 0.9 3.3 2 1 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KEY65718.1 - 0.017 15.3 0.0 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 KEY65718.1 - 0.082 12.6 0.3 9 6.1 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF861) AraC_binding_2 PF14525.6 KEY65718.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AraC-binding-like domain Oxysterol_BP PF01237.18 KEY65720.1 - 7.9e-132 439.6 0.1 2.8e-131 437.8 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Glyco_hydro_18 PF00704.28 KEY65720.1 - 1.8e-17 64.0 0.7 3.9e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Ank_5 PF13857.6 KEY65720.1 - 1.6e-14 53.8 0.0 2e-09 37.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY65720.1 - 1.9e-12 47.6 0.0 3.8e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KEY65720.1 - 3.1e-12 46.9 0.9 7.3e-12 45.7 0.9 1.7 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KEY65720.1 - 3.1e-11 42.5 0.0 0.00099 19.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KEY65720.1 - 8.2e-11 41.8 0.1 6.2e-05 23.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KEY65720.1 - 4.3e-09 36.7 0.0 1.7e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KEY65720.1 - 1.1e-07 32.1 1.0 2.4e-07 30.9 1.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KEY65720.1 - 0.00014 22.2 2.0 0.00014 22.2 2.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain 4HBT_3 PF13622.6 KEY65721.1 - 3e-81 273.3 4.1 3.6e-81 273.1 4.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KEY65721.1 - 3e-24 85.3 0.0 4.4e-12 46.0 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Asp PF00026.23 KEY65722.1 - 2.9e-59 201.0 0.1 9.3e-50 169.8 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY65722.1 - 2e-12 47.7 0.2 2.5e-11 44.2 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY65722.1 - 7.3e-06 26.5 1.1 0.65 10.7 0.0 3.6 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KEY65722.1 - 0.00038 21.0 0.2 3.8 8.2 0.0 3.7 3 1 1 4 4 4 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KEY65722.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal RRM_1 PF00076.22 KEY65723.1 - 1.1e-09 38.0 0.0 2.9e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 KEY65723.1 - 2e-09 37.2 0.4 4.2e-09 36.1 0.4 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KEY65723.1 - 3.5e-05 23.0 4.7 7.6e-05 21.9 4.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KEY65723.1 - 5.6e-05 23.2 0.7 0.00019 21.5 0.7 2.0 1 0 0 1 1 1 1 G-patch domain zf-C2H2_2 PF12756.7 KEY65723.1 - 0.15 12.4 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KEY65723.1 - 0.61 10.2 5.1 0.34 11.0 2.8 1.7 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 KEY65723.1 - 5.3 7.0 8.6 1.3 9.0 4.5 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MoaE PF02391.17 KEY65724.1 - 2e-39 134.4 0.0 2.5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Lipase_GDSL_lke PF16255.5 KEY65724.1 - 0.0058 16.0 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ferric_reduct PF01794.19 KEY65726.1 - 2.8e-20 72.7 4.7 2.8e-20 72.7 4.7 3.2 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY65726.1 - 8.5e-13 48.7 0.0 2.1e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY65726.1 - 1.2e-12 47.8 0.0 2.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KEY65726.1 - 0.0046 17.6 0.0 0.6 10.8 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 KEY65726.1 - 0.31 11.6 5.6 0.26 11.9 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RNase_PH PF01138.21 KEY65727.1 - 1.7e-18 67.4 0.0 3.3e-18 66.4 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEY65727.1 - 0.012 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 GDI PF00996.18 KEY65728.1 - 1.6e-27 96.2 0.0 2.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 KEY65729.1 - 1.5e-30 105.6 0.0 2.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KEY65729.1 - 5.8e-06 25.5 0.0 1.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Aminotran_1_2 PF00155.21 KEY65730.1 - 2.1e-28 99.6 0.0 2.6e-22 79.5 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Fungal_trans PF04082.18 KEY65731.1 - 2.8e-08 33.1 0.0 6.7e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY65731.1 - 0.0026 17.8 7.1 0.0058 16.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.22 KEY65732.1 - 4.5e-12 45.1 11.7 0.003 17.7 0.0 9.2 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.6 KEY65732.1 - 6.8e-12 45.6 7.7 1.8e-08 34.7 0.0 7.8 8 2 1 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 KEY65732.1 - 1.5e-08 34.4 6.3 1.4e-07 31.3 1.8 4.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KEY65732.1 - 2.7e-08 34.1 12.7 0.009 16.4 0.0 6.8 4 2 1 6 6 6 2 HEAT repeats MMS19_C PF12460.8 KEY65732.1 - 8.6e-07 28.4 0.1 0.0028 16.8 0.1 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KEY65732.1 - 0.00016 21.3 4.4 3.7 7.0 0.2 5.0 2 1 4 6 6 6 2 CLASP N terminal DUF3385 PF11865.8 KEY65732.1 - 0.0018 18.2 0.3 1.3 8.9 0.0 4.4 2 2 1 3 3 3 1 Domain of unknown function (DUF3385) Arm PF00514.23 KEY65732.1 - 0.018 15.1 4.3 4.7 7.4 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KEY65732.1 - 0.076 13.7 2.9 1.1e+02 3.9 0.0 5.6 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Cse1 PF08506.10 KEY65732.1 - 0.1 11.4 0.0 0.72 8.6 0.0 2.4 3 0 0 3 3 3 0 Cse1 NUC173 PF08161.12 KEY65732.1 - 0.25 11.0 4.0 7.6 6.1 0.0 4.4 4 2 1 5 5 5 0 NUC173 domain Abhydrolase_1 PF00561.20 KEY65734.1 - 1.4e-21 77.3 0.4 8.2e-21 74.8 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY65734.1 - 2.1e-19 71.0 1.2 2.7e-19 70.7 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY65734.1 - 2.3e-09 36.9 0.1 8.5e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEY65734.1 - 0.029 14.5 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Lipase_2 PF01674.18 KEY65734.1 - 0.04 13.4 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 2) Ndr PF03096.14 KEY65734.1 - 0.042 12.5 0.0 0.15 10.7 0.0 1.8 1 1 0 1 1 1 0 Ndr family PFK PF00365.20 KEY65735.1 - 5.3e-188 623.2 0.9 1.7e-105 352.4 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KEY65735.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif DAGK_cat PF00781.24 KEY65735.1 - 0.14 11.8 0.1 0.8 9.3 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Med17 PF10156.9 KEY65736.1 - 1.2e-89 301.1 0.0 1.6e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex SNF2_N PF00176.23 KEY65737.1 - 8.4e-60 202.3 0.7 8.4e-60 202.3 0.7 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY65737.1 - 2.2e-14 53.8 0.0 5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KEY65737.1 - 3.7e-07 29.9 8.5 7.8e-07 28.9 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY65737.1 - 3.7e-07 29.9 5.9 7.8e-07 28.9 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY65737.1 - 1.1e-06 28.4 4.8 1.1e-06 28.4 4.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY65737.1 - 2.8e-06 27.3 2.9 2.8e-06 27.3 2.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger ResIII PF04851.15 KEY65737.1 - 6.7e-06 26.2 0.2 1.6e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KEY65737.1 - 0.00013 22.2 8.1 0.00013 22.2 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain SPT6_acidic PF14632.6 KEY65737.1 - 0.0014 19.2 5.8 0.0054 17.3 5.8 2.0 1 0 0 1 1 1 1 Acidic N-terminal SPT6 zf-C3HC4_4 PF15227.6 KEY65737.1 - 0.0019 18.3 7.9 0.0055 16.8 7.9 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KEY65737.1 - 0.012 15.6 7.7 0.041 13.9 7.7 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Tmpp129 PF10272.9 KEY65737.1 - 0.037 13.3 3.2 0.14 11.4 1.2 2.3 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-RING_4 PF14570.6 KEY65737.1 - 0.043 13.6 5.9 0.97 9.3 6.8 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF86 PF01934.17 KEY65737.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF86 Baculo_IE-1 PF05290.11 KEY65737.1 - 0.24 11.3 3.6 0.11 12.4 1.2 1.7 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KEY65737.1 - 0.43 10.9 5.0 1 9.7 5.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain CBP4 PF07960.11 KEY65737.1 - 1.2 9.0 5.2 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 CBP4 Prok-RING_4 PF14447.6 KEY65737.1 - 5.3 7.0 14.5 92 3.0 0.8 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Phosphodiest PF01663.22 KEY65738.1 - 5.8e-94 315.6 0.7 7.6e-94 315.2 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEY65738.1 - 0.0044 16.4 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 KEY65738.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Zn_clus PF00172.18 KEY65739.1 - 3.3e-07 30.3 9.0 3.3e-07 30.3 9.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KEY65740.1 - 2.4e-32 112.3 0.0 2.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY65740.1 - 1.5e-23 83.6 0.0 2.1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY65740.1 - 4.3e-06 26.4 0.0 1.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HAD PF12710.7 KEY65740.1 - 0.0049 17.3 0.0 0.0098 16.3 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AP_endonuc_2 PF01261.24 KEY65740.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_76 PF03663.14 KEY65741.1 - 1.5e-156 521.5 11.5 1.8e-156 521.3 11.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY65741.1 - 0.13 11.3 6.3 0.091 11.8 1.9 2.4 1 1 2 3 3 3 0 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.21 KEY65742.1 - 1.2e-33 114.8 0.6 1.3e-33 114.6 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KEY65742.1 - 0.043 14.5 0.0 0.11 13.1 0.0 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 KEY65742.1 - 0.073 13.2 0.0 0.083 13.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EMP24_GP25L PF01105.24 KEY65742.1 - 0.084 12.8 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NAT PF04768.13 KEY65743.1 - 2.1e-46 157.7 0.0 3.8e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KEY65743.1 - 1.6e-31 109.7 0.0 2.5e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family p450 PF00067.22 KEY65744.1 - 8.3e-59 199.5 0.0 1.1e-58 199.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 KEY65745.1 - 1.2e-15 57.1 0.0 1.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY65745.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CoxIIa PF08113.11 KEY65745.1 - 0.39 10.6 3.1 0.79 9.6 3.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Fasciclin PF02469.22 KEY65746.1 - 2.4e-37 128.0 0.0 2.1e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.21 KEY65748.1 - 3.8e-16 59.0 1.0 5.9e-16 58.4 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KEY65749.1 - 1.2e-50 172.2 5.1 1.2e-50 172.2 5.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEY65749.1 - 1.1e-05 25.4 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEY65749.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEY65749.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 ABC_tran PF00005.27 KEY65750.1 - 5.6e-48 162.9 0.0 1.2e-25 90.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEY65750.1 - 3.4e-14 53.4 6.2 0.0003 20.7 1.8 5.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY65750.1 - 3.2e-13 49.6 0.0 7.2e-05 22.3 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KEY65750.1 - 3.8e-09 36.3 0.0 7.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KEY65750.1 - 7.4e-09 36.4 0.6 0.0004 20.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KEY65750.1 - 2.1e-07 31.0 0.0 0.0039 17.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KEY65750.1 - 5.2e-07 29.3 0.5 0.007 16.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY65750.1 - 5.6e-07 29.6 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KEY65750.1 - 4.8e-05 23.9 0.0 0.022 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEY65750.1 - 5.7e-05 23.4 0.0 0.0049 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY65750.1 - 5.9e-05 23.4 0.1 0.79 10.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEY65750.1 - 0.00023 21.0 0.1 0.24 11.1 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KEY65750.1 - 0.00079 19.6 0.6 0.35 10.9 0.0 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 KEY65750.1 - 0.001 19.4 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KEY65750.1 - 0.0019 18.1 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KEY65750.1 - 0.0019 18.3 0.0 3.1 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY65750.1 - 0.0028 17.4 0.1 2.5 7.8 0.0 3.4 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KEY65750.1 - 0.0058 16.8 0.0 4 7.8 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KEY65750.1 - 0.0075 16.0 0.3 0.6 9.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY65750.1 - 0.0076 16.6 0.1 1.3 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 KEY65750.1 - 0.0077 15.2 0.3 1.9 7.4 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KEY65750.1 - 0.0098 16.3 0.0 6.2 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KEY65750.1 - 0.011 14.4 0.0 1.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 KEY65750.1 - 0.015 14.9 4.0 0.025 14.2 4.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PduV-EutP PF10662.9 KEY65750.1 - 0.018 14.8 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 KEY65750.1 - 0.03 11.8 1.3 2.1 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NB-ARC PF00931.22 KEY65750.1 - 0.043 13.0 0.1 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MukB PF04310.12 KEY65750.1 - 0.047 13.5 0.2 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF815 PF05673.13 KEY65750.1 - 0.055 12.6 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KEY65750.1 - 0.064 12.8 1.8 9.1 5.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain CLASP_N PF12348.8 KEY65750.1 - 0.064 12.8 0.0 9.4 5.7 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal AAA_14 PF13173.6 KEY65750.1 - 0.072 13.1 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KEY65750.1 - 0.082 13.1 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KEY65750.1 - 0.085 12.9 0.2 19 5.3 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KEY65750.1 - 0.092 12.8 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KEY65750.1 - 0.11 12.4 0.1 14 5.5 0.1 2.7 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KEY65750.1 - 0.14 11.9 0.4 52 3.6 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 KEY65750.1 - 0.57 9.7 2.1 20 4.6 0.1 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region DHHC PF01529.20 KEY65751.1 - 5.1e-39 133.4 5.0 1.1e-38 132.3 5.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase HAD PF12710.7 KEY65753.1 - 2.3e-21 77.1 0.1 3.1e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY65753.1 - 6.7e-14 52.7 0.5 1.3e-13 51.7 0.5 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEY65753.1 - 1.2e-07 31.8 2.3 3.8e-07 30.1 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEY65753.1 - 0.00034 20.7 0.0 0.0022 18.1 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KEY65753.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PAPS_reduct PF01507.19 KEY65754.1 - 1.9e-42 145.2 0.0 3e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TYW3 PF02676.14 KEY65755.1 - 1.8e-76 256.2 0.0 2.3e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 KEY65756.1 - 6.5e-34 117.3 7.1 7.7e-34 117.1 7.1 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Spc7 PF08317.11 KEY65756.1 - 0.03 13.2 5.4 0.035 13.0 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 KEY65756.1 - 0.07 13.4 5.2 0.13 12.6 0.9 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Retrotrans_gag PF03732.17 KEY65756.1 - 0.11 12.8 1.3 0.22 11.8 1.3 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Rootletin PF15035.6 KEY65756.1 - 0.3 11.1 8.5 0.56 10.2 8.5 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Ferric_reduct PF01794.19 KEY65757.1 - 8.2e-24 84.1 7.7 8.2e-24 84.1 7.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY65757.1 - 1.8e-18 67.2 0.0 1.1e-15 58.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY65757.1 - 3e-08 33.7 0.1 2.6e-06 27.5 0.1 2.6 1 1 0 1 1 1 1 FAD-binding domain TP_methylase PF00590.20 KEY65758.1 - 1.8e-46 158.8 2.3 2.3e-46 158.4 0.8 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KEY65758.1 - 3.7e-14 53.0 0.0 6.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KEY65758.1 - 1.7e-10 40.2 0.0 3.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KEY65758.1 - 2.4e-10 39.9 0.1 2e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 Sirohaem biosynthesis protein C-terminal Rsm22 PF09243.10 KEY65759.1 - 8.7e-32 110.5 0.0 6.7e-31 107.6 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_12 PF08242.12 KEY65759.1 - 0.035 14.9 0.0 0.091 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEY65759.1 - 0.061 14.0 0.0 0.19 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.20 KEY65760.1 - 4.8e-26 90.7 0.0 6.6e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY65760.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEY65760.1 - 0.0013 19.1 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KEY65760.1 - 0.0018 17.7 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KEY65760.1 - 0.002 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KEY65760.1 - 0.016 14.9 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 KEY65760.1 - 0.17 11.6 0.0 0.58 9.9 0.0 1.7 1 1 1 2 2 2 0 Redoxin Methyltrn_RNA_3 PF02598.17 KEY65761.1 - 1.2e-103 346.5 0.0 1.4e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Pectate_lyase_3 PF12708.7 KEY65762.1 - 5.1e-80 268.3 4.1 2.6e-71 239.9 0.1 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEY65762.1 - 9.7e-07 28.4 1.3 0.036 13.8 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 KEY65762.1 - 0.0059 16.5 1.4 0.013 15.4 0.6 2.0 2 0 0 2 2 2 1 Right handed beta helix region LIAS_N PF16881.5 KEY65763.1 - 1.3e-17 64.2 0.0 2.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KEY65763.1 - 4.5e-14 53.2 0.0 7.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Methyltransf_25 PF13649.6 KEY65764.1 - 1.7e-18 67.1 0.1 2e-17 63.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65764.1 - 1.4e-15 57.7 0.0 4.2e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY65764.1 - 2.8e-09 36.9 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY65764.1 - 1.4e-08 34.7 0.0 2.1e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY65764.1 - 1.5e-08 35.3 0.0 3.7e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY65764.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEY65764.1 - 8.1e-05 22.1 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KEY65764.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEY65764.1 - 0.0057 16.1 0.0 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEY65764.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KEY65764.1 - 0.025 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_24 PF13578.6 KEY65764.1 - 0.029 15.4 0.0 0.31 12.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Endonuc-dimeris PF09124.10 KEY65764.1 - 0.044 13.9 0.0 0.5 10.6 0.0 2.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation PrpF PF04303.13 KEY65766.1 - 5.5e-108 361.2 0.4 6.4e-108 361.0 0.4 1.0 1 0 0 1 1 1 1 PrpF protein Uroplakin_II PF07353.12 KEY65766.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Uroplakin II FANCI_S4 PF14678.6 KEY65768.1 - 0.078 12.1 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 FANCI solenoid 4 YqzE PF14038.6 KEY65768.1 - 2.8 8.0 6.2 0.22 11.5 1.2 1.7 2 0 0 2 2 2 0 YqzE-like protein SRP_TPR_like PF17004.5 KEY65769.1 - 1.5e-24 86.3 3.1 3e-22 78.8 1.4 2.5 2 0 0 2 2 2 2 Putative TPR-like repeat SRP72 PF08492.12 KEY65769.1 - 4.3e-16 59.1 7.0 4.3e-16 59.1 7.0 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KEY65769.1 - 5.5e-05 23.6 37.4 0.089 13.3 1.3 7.3 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65769.1 - 0.00012 21.9 22.9 0.89 9.8 0.2 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY65769.1 - 0.0011 19.1 11.4 0.024 14.9 3.1 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEY65769.1 - 0.0026 18.4 33.3 0.83 10.6 1.4 8.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65769.1 - 0.011 16.0 24.4 0.09 13.1 1.8 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY65769.1 - 0.025 15.2 1.9 0.025 15.2 1.9 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat FANCI_S2 PF14676.6 KEY65769.1 - 0.032 14.5 0.1 0.091 13.1 0.0 1.8 2 0 0 2 2 2 0 FANCI solenoid 2 SPO22 PF08631.10 KEY65769.1 - 0.038 13.5 3.2 0.068 12.6 0.1 2.8 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF4810 PF16068.5 KEY65769.1 - 0.078 13.5 0.7 21 5.7 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4810) PPR PF01535.20 KEY65769.1 - 0.12 12.7 0.6 51 4.4 0.0 3.9 4 0 0 4 4 3 0 PPR repeat TPR_11 PF13414.6 KEY65769.1 - 0.22 11.2 5.8 2.4 7.9 0.0 3.5 4 0 0 4 4 4 0 TPR repeat ELYS PF13934.6 KEY65769.1 - 0.34 10.9 3.4 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Nuclear pore complex assembly GGA_N-GAT PF18308.1 KEY65769.1 - 0.42 10.3 3.3 11 5.7 0.3 2.9 2 0 0 2 2 2 0 GGA N-GAT domain TPR_10 PF13374.6 KEY65769.1 - 2.3 8.2 16.8 10 6.1 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Sec7 PF01369.20 KEY65770.1 - 5.4e-31 107.7 0.1 9.6e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KEY65770.1 - 0.00032 21.2 0.0 0.00086 19.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KEY65770.1 - 0.002 18.5 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain YfdX PF10938.8 KEY65770.1 - 0.034 14.1 1.1 0.073 13.0 1.1 1.5 1 0 0 1 1 1 0 YfdX protein Peptidase_M14 PF00246.24 KEY65771.1 - 1e-73 248.7 0.0 1.3e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MAPEG PF01124.18 KEY65772.1 - 3.2e-20 72.3 1.1 4e-20 72.1 1.1 1.1 1 0 0 1 1 1 1 MAPEG family DNA_pol_B_palm PF14792.6 KEY65773.1 - 6.2e-22 78.0 0.0 1.2e-21 77.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KEY65773.1 - 1.6e-20 73.0 0.1 3.1e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KEY65773.1 - 7.1e-11 41.8 0.2 1.8e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KEY65773.1 - 9.9e-05 22.6 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KEY65773.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain MBD PF01429.19 KEY65773.1 - 0.035 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain SMC_N PF02463.19 KEY65774.1 - 1.3e-48 165.4 35.9 4.1e-48 163.7 35.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEY65774.1 - 5e-26 91.3 0.0 2.2e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KEY65774.1 - 3.2e-10 40.3 3.2 3.2e-10 40.3 3.2 4.4 2 2 2 4 4 4 1 AAA ATPase domain TFIIE_alpha PF02002.17 KEY65774.1 - 2.7e-08 33.6 0.3 2.3e-07 30.6 0.3 2.7 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_21 PF13304.6 KEY65774.1 - 4.5e-08 33.3 14.9 4.2e-05 23.5 0.8 3.6 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY65774.1 - 6.9e-08 32.1 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.12 KEY65774.1 - 0.0016 18.5 17.1 0.0016 18.5 17.1 9.0 5 2 4 9 9 9 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KEY65774.1 - 0.0017 17.3 124.3 0.043 12.7 14.9 7.5 3 2 4 7 7 7 5 Spc7 kinetochore protein SbcCD_C PF13558.6 KEY65774.1 - 0.013 15.7 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2838 PF10998.8 KEY65775.1 - 4.1e-45 152.6 9.7 4.1e-45 152.6 9.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 KEY65775.1 - 0.24 11.2 5.0 0.43 10.4 5.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 KEY65776.1 - 1.9e-18 66.5 17.6 0.00016 22.4 0.3 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65776.1 - 6.2e-14 52.1 5.7 6.9e-05 23.1 0.5 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY65776.1 - 5.3e-07 29.7 0.1 0.0024 17.8 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A STAG PF08514.11 KEY65777.1 - 0.028 14.3 1.7 0.097 12.6 1.4 1.8 1 1 1 2 2 2 0 STAG domain Acetyltransf_1 PF00583.25 KEY65778.1 - 2.2e-12 47.2 0.0 3.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY65778.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY65778.1 - 3.6e-08 33.7 0.0 5.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY65778.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KEY65778.1 - 0.12 12.5 0.2 0.34 11.0 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1793 PF08760.11 KEY65779.1 - 7.9e-70 234.6 0.3 1.5e-69 233.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KEY65779.1 - 1.6e-68 229.7 0.3 6.7e-54 182.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KEY65779.1 - 1.9e-39 135.8 0.3 3.5e-39 134.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KEY65779.1 - 0.00088 18.8 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KEY65779.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RRM_1 PF00076.22 KEY65780.1 - 2.7e-20 72.0 0.0 3.9e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY65780.1 - 8.2e-05 22.2 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.11 KEY65781.1 - 1.4e-260 866.9 0.0 1.7e-260 866.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KEY65782.1 - 0.00015 21.9 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KEY65782.1 - 0.059 13.7 1.7 0.15 12.5 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KEY65782.1 - 0.14 12.4 1.7 0.16 12.2 1.0 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb ABC_tran_Xtn PF12848.7 KEY65783.1 - 0.0062 16.5 3.0 0.011 15.7 3.0 1.3 1 0 0 1 1 1 1 ABC transporter TPR_MLP1_2 PF07926.12 KEY65783.1 - 0.0093 16.0 6.0 0.015 15.4 6.0 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 KEY65783.1 - 0.015 15.1 0.3 0.034 14.0 0.1 1.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myb_DNA-binding PF00249.31 KEY65785.1 - 5.2e-21 74.6 1.6 1.4e-11 44.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY65785.1 - 3.3e-13 49.7 0.3 4.8e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KEY65785.1 - 0.015 15.6 1.9 0.13 12.6 0.4 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2774 PF11242.8 KEY65785.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Peptidase_M13_N PF05649.13 KEY65785.1 - 0.066 12.9 0.1 0.087 12.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M13 DUF722 PF05263.11 KEY65785.1 - 0.15 12.2 0.4 10 6.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF722) Glyco_transf_41 PF13844.6 KEY65786.1 - 3.2e-100 335.8 0.0 1.2e-50 172.3 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KEY65786.1 - 2e-22 78.0 5.9 2.1e-05 24.1 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65786.1 - 5.7e-19 66.6 5.5 0.004 17.2 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KEY65786.1 - 1.1e-14 53.8 2.1 0.0024 17.5 0.1 5.5 2 2 3 5 5 5 4 TPR repeat TPR_8 PF13181.6 KEY65786.1 - 2.7e-14 52.1 1.1 0.00073 19.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65786.1 - 8.2e-10 38.8 8.7 0.11 12.8 0.0 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEY65786.1 - 1.2e-09 37.9 0.4 0.0028 17.9 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY65786.1 - 1.3e-09 37.6 8.8 0.013 15.3 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY65786.1 - 5.4e-09 36.6 2.5 0.22 12.2 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65786.1 - 8e-09 35.6 6.2 0.25 12.2 0.1 5.4 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY65786.1 - 3.1e-06 27.6 3.2 0.68 10.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65786.1 - 0.00024 20.9 2.7 1.4 9.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEY65786.1 - 0.00072 18.9 0.1 0.34 10.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY65786.1 - 0.022 15.0 0.4 0.53 10.6 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEY65786.1 - 0.49 10.6 4.2 1.8 8.7 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KEY65786.1 - 0.56 10.6 2.6 1.9 8.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Statherin PF03875.13 KEY65786.1 - 6.3 7.0 7.8 0.88 9.7 1.3 2.8 2 0 0 2 2 2 0 Statherin Ribosomal_L11_N PF03946.14 KEY65787.1 - 8.2e-25 86.4 0.1 1.3e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KEY65787.1 - 3.5e-17 62.7 0.2 6.1e-17 61.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 KEY65788.1 - 1.9e-79 266.7 0.0 2.7e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KEY65788.1 - 1.7e-30 105.6 0.1 3.6e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KEY65788.1 - 1.6e-25 88.9 0.3 4.8e-25 87.4 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KEY65788.1 - 1.4e-15 57.1 6.7 2.5e-15 56.2 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KEY65788.1 - 5e-13 48.8 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KEY65788.1 - 0.078 12.4 1.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain tRNA-synt_1 PF00133.22 KEY65790.1 - 3.1e-149 498.0 0.0 4.9e-149 497.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEY65790.1 - 7.3e-21 74.4 0.0 1.7e-12 46.8 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEY65790.1 - 6.9e-18 65.1 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA ADK_lid PF05191.14 KEY65790.1 - 0.021 14.8 1.2 0.044 13.8 1.2 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid tRNA-synt_1e PF01406.19 KEY65790.1 - 0.022 14.1 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KEY65790.1 - 0.97 9.4 4.3 2.4 8.1 4.3 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SET PF00856.28 KEY65792.1 - 1.8e-07 31.7 0.0 5.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KEY65792.1 - 6 7.1 15.1 0.062 13.4 6.5 2.3 2 0 0 2 2 2 0 MYND finger CH PF00307.31 KEY65793.1 - 9.5e-15 54.7 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 KEY65793.1 - 0.064 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 KEY65793.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 KEY65794.1 - 4.6e-12 46.6 1.0 4.6e-12 46.6 1.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Gag_p12 PF01141.18 KEY65794.1 - 0.0068 16.7 2.7 0.012 16.0 2.7 1.4 1 0 0 1 1 1 1 Gag polyprotein, inner coat protein p12 SOCS_box PF07525.16 KEY65795.1 - 0.096 13.1 0.4 0.18 12.2 0.4 1.5 1 0 0 1 1 1 0 SOCS box HABP4_PAI-RBP1 PF04774.15 KEY65797.1 - 0.00011 23.1 6.8 0.00011 23.1 6.8 2.6 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KEY65797.1 - 0.00035 21.4 5.6 0.00035 21.4 5.6 4.4 4 1 0 4 4 4 1 Stm1 Nefa_Nip30_N PF10187.9 KEY65797.1 - 1.6 9.1 11.3 31 5.0 11.3 2.2 1 1 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF1010 PF06231.11 KEY65798.1 - 0.0079 16.7 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1010) PHD PF00628.29 KEY65799.1 - 3.5e-10 39.6 5.7 5.6e-10 39.0 5.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEY65799.1 - 0.016 14.8 1.6 0.027 14.0 1.6 1.3 1 0 0 1 1 1 0 PHD-finger DUF4451 PF14616.6 KEY65800.1 - 2.3e-24 85.9 0.1 4.3e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Actin PF00022.19 KEY65803.1 - 1.8e-28 99.3 0.0 3.8e-19 68.6 0.0 3.0 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KEY65803.1 - 7.1e-05 22.1 0.9 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KEY65803.1 - 0.0054 17.1 0.0 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 Cell division protein FtsA preATP-grasp_3 PF18301.1 KEY65803.1 - 0.099 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 pre ATP-grasp 3 domain MreB_Mbl PF06723.13 KEY65803.1 - 0.24 10.1 0.0 0.85 8.4 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.16 KEY65804.1 - 1.5e-24 86.6 27.3 7e-13 48.2 6.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY65804.1 - 1.4e-06 27.5 0.0 0.034 13.0 0.0 3.1 3 1 0 3 3 3 2 MFS_1 like family ATG22 PF11700.8 KEY65804.1 - 5.6e-06 25.3 4.4 6.4e-06 25.1 0.0 2.8 2 2 2 4 4 4 2 Vacuole effluxer Atg22 like LacY_symp PF01306.19 KEY65804.1 - 0.65 8.7 12.9 0.078 11.7 3.6 2.8 3 0 0 3 3 3 0 LacY proton/sugar symporter CbtA PF09490.10 KEY65804.1 - 1.8 8.3 13.8 1 9.0 6.2 3.4 3 1 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) Med10 PF09748.9 KEY65806.1 - 5.5e-50 168.4 0.1 6.4e-50 168.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KEY65806.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) TPR_2 PF07719.17 KEY65807.1 - 1.2e-36 121.8 7.1 1.7e-05 24.6 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEY65807.1 - 3.6e-34 115.2 7.1 1.5e-07 30.9 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEY65807.1 - 1.1e-29 101.8 8.0 2.4e-09 36.7 0.0 6.9 5 1 1 6 6 6 5 TPR repeat TPR_19 PF14559.6 KEY65807.1 - 4.2e-27 94.4 11.9 1.8e-09 38.0 0.0 6.1 4 3 2 6 6 5 5 Tetratricopeptide repeat DnaJ PF00226.31 KEY65807.1 - 2.8e-26 91.4 2.1 8.5e-26 89.9 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 KEY65807.1 - 2.7e-20 72.7 3.3 3.7e-08 33.9 0.2 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65807.1 - 4.1e-20 70.7 6.6 0.00042 20.9 0.5 8.3 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEY65807.1 - 1.1e-19 68.9 5.9 0.00074 19.5 0.3 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEY65807.1 - 4.8e-17 61.9 0.8 1.9e-06 27.9 0.0 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY65807.1 - 1.9e-16 60.1 6.4 0.00025 21.3 0.1 5.7 4 2 1 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY65807.1 - 7e-15 55.0 1.2 2.8e-07 30.7 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEY65807.1 - 5e-14 51.6 10.3 0.0065 16.8 0.0 6.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEY65807.1 - 8.9e-12 44.8 12.1 0.17 12.6 0.0 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65807.1 - 1.6e-10 40.2 0.2 0.13 12.3 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEY65807.1 - 1e-09 38.0 5.7 0.0044 16.3 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KEY65807.1 - 5.2e-06 26.6 0.2 0.54 11.0 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 KEY65807.1 - 1.8e-05 25.2 8.4 0.28 11.6 0.1 5.0 3 2 3 6 6 5 2 Bacterial transcriptional activator domain Coatomer_E PF04733.14 KEY65807.1 - 2.7e-05 23.7 0.3 0.028 13.9 0.0 3.1 3 1 1 4 4 4 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 KEY65807.1 - 0.0003 21.3 2.1 0.68 10.4 0.0 3.5 2 1 0 2 2 2 1 Alkyl sulfatase dimerisation SNAP PF14938.6 KEY65807.1 - 0.0011 18.5 2.0 0.19 11.1 0.1 2.5 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 KEY65807.1 - 0.0012 19.1 5.5 9.6 6.6 0.0 5.0 3 2 2 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY65807.1 - 0.0015 18.3 8.7 3.8 7.5 0.4 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat YfiO PF13525.6 KEY65807.1 - 0.0024 17.6 2.5 0.04 13.6 0.4 2.6 2 0 0 2 2 2 1 Outer membrane lipoprotein MIT PF04212.18 KEY65807.1 - 0.0026 17.8 6.7 0.33 11.0 0.0 4.0 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 KEY65807.1 - 0.0059 15.6 2.4 1.5 7.7 0.1 3.3 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 KEY65807.1 - 0.016 15.2 5.6 75 3.5 0.0 5.1 5 1 1 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 KEY65807.1 - 0.1 12.6 0.7 2.2 8.3 0.1 3.1 4 0 0 4 4 3 0 Putative TPR-like repeat ChAPs PF09295.10 KEY65807.1 - 0.13 11.2 0.3 1.1 8.2 0.0 2.3 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPM_phosphatase PF04536.14 KEY65807.1 - 0.13 12.4 1.5 11 6.2 0.0 3.1 2 1 1 3 3 3 0 TPM domain DUF3856 PF12968.7 KEY65807.1 - 0.38 10.8 4.6 58 3.7 0.0 5.4 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) Wzy_C_2 PF11846.8 KEY65807.1 - 0.48 10.3 4.7 1.7 8.5 0.1 2.8 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Metal_resist PF13801.6 KEY65807.1 - 2.9 8.1 5.7 3.2 7.9 0.4 3.5 3 0 0 3 3 2 0 Heavy-metal resistance EF-hand_6 PF13405.6 KEY65808.1 - 3.8e-11 42.0 1.2 5.6e-05 22.8 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KEY65808.1 - 1.2e-08 33.8 1.5 0.0045 16.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KEY65808.1 - 2e-05 25.0 0.5 0.00043 20.7 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEY65808.1 - 2e-05 24.4 0.0 0.055 13.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KEY65808.1 - 0.00037 20.8 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KEY65808.1 - 0.0036 16.7 4.0 0.7 9.5 0.4 2.4 2 0 0 2 2 2 2 EF hand Afi1 PF07792.12 KEY65809.1 - 1.6e-45 154.9 1.4 3e-45 154.0 1.4 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KEY65809.1 - 1.2e-35 121.9 0.0 2.2e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KEY65809.1 - 1.9e-06 26.9 0.1 0.068 11.8 0.0 3.5 3 1 1 4 4 4 2 Transport protein Avl9 Cwf_Cwc_15 PF04889.12 KEY65809.1 - 0.0038 17.0 13.5 0.0083 15.9 13.5 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KEY65809.1 - 0.0077 16.6 4.6 0.0077 16.6 4.6 2.1 2 0 0 2 2 2 1 Centromere protein B dimerisation domain DUF1168 PF06658.12 KEY65809.1 - 0.058 13.2 12.2 0.14 12.0 12.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2347 PF09804.9 KEY65809.1 - 0.074 12.6 0.0 0.39 10.3 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF4746 PF15928.5 KEY65809.1 - 0.73 9.2 4.3 1.4 8.3 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 KEY65809.1 - 1.2 8.2 8.0 2.7 7.1 7.8 1.7 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Esterase PF00756.20 KEY65810.1 - 1.6e-51 175.4 0.0 1.9e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KEY65810.1 - 0.00021 20.8 0.0 0.002 17.7 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEY65810.1 - 0.0042 16.4 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY65810.1 - 0.0058 16.1 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KEY65810.1 - 0.0094 15.5 0.0 0.018 14.6 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KEY65810.1 - 0.034 13.1 0.0 0.07 12.0 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KEY65810.1 - 0.055 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KEY65810.1 - 0.08 11.6 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 KEY65810.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KEY65810.1 - 0.25 11.0 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpb6 PF01192.22 KEY65812.1 - 3.6e-17 62.0 0.2 6.5e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 KEY65812.1 - 0.022 14.7 1.0 0.036 14.0 1.0 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C2H2 PF00096.26 KEY65813.1 - 4.1e-29 99.4 58.3 1.8e-05 24.9 1.7 10.7 10 1 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY65813.1 - 1.8e-22 78.0 60.3 0.0017 19.0 1.2 10.8 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY65813.1 - 2.2e-12 46.8 53.7 0.00075 19.8 0.2 10.8 11 1 0 11 11 11 5 Zinc-finger double domain FOXP-CC PF16159.5 KEY65813.1 - 1.1e-05 26.0 33.0 0.0073 16.9 0.2 7.0 4 1 3 7 7 7 4 FOXP coiled-coil domain zf-met PF12874.7 KEY65813.1 - 0.00019 21.7 12.8 0.96 9.9 0.0 6.7 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KEY65813.1 - 0.00023 21.4 19.9 0.12 12.7 5.9 5.0 3 1 1 5 5 5 2 C2H2-type zinc ribbon zf_Hakai PF18408.1 KEY65813.1 - 0.0044 16.7 15.1 0.78 9.5 0.1 5.8 5 0 0 5 5 5 1 C2H2 Hakai zinc finger domain zf-C2H2_3rep PF18868.1 KEY65813.1 - 0.0057 17.3 27.5 0.25 12.0 2.6 5.5 3 2 2 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KEY65813.1 - 0.0072 16.1 1.8 0.0072 16.1 1.8 9.2 10 0 0 10 10 10 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KEY65813.1 - 0.022 15.1 2.8 0.022 15.1 2.8 7.1 6 1 2 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KEY65813.1 - 0.03 14.6 31.2 1.6 9.1 0.0 8.4 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KEY65813.1 - 0.22 11.6 8.1 0.55 10.3 0.2 3.5 3 0 0 3 3 3 0 CpXC protein zf-C2H2_aberr PF17017.5 KEY65813.1 - 0.31 11.2 20.4 8.5 6.5 2.9 4.7 2 1 3 5 5 5 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KEY65813.1 - 2 8.5 34.4 0.52 10.4 1.5 6.8 7 0 0 7 7 7 0 C2H2-type zinc finger Zip PF02535.22 KEY65814.1 - 6.3e-31 107.8 8.8 4e-28 98.6 8.8 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter OATP PF03137.20 KEY65814.1 - 0.0096 14.2 0.0 0.16 10.2 0.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Endonuclease_NS PF01223.23 KEY65815.1 - 2.8e-64 217.0 0.0 3.5e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 KEY65816.1 - 5e-31 106.3 25.7 7.7e-06 26.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65816.1 - 1.4e-13 51.0 0.1 0.028 14.7 0.0 5.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY65816.1 - 0.0049 16.8 0.0 0.54 10.1 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEY65816.1 - 0.084 11.8 0.1 16 4.3 0.0 3.1 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KEY65816.1 - 0.1 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz MBOAT PF03062.19 KEY65817.1 - 1e-19 71.1 10.5 1e-19 71.1 10.5 1.8 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KEY65817.1 - 0.00024 21.3 2.0 0.00077 19.7 2.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.14 KEY65818.1 - 2.9e-27 94.9 1.0 4.3e-27 94.4 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KEY65818.1 - 1e-10 42.0 1.4 1e-10 42.0 1.4 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KEY65818.1 - 0.0051 16.4 3.4 0.0069 15.9 2.6 1.7 1 1 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 KEY65818.1 - 0.008 15.7 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3188 PF11384.8 KEY65818.1 - 0.024 14.4 0.9 0.2 11.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Tmemb_170 PF10190.9 KEY65819.1 - 8.5e-27 93.6 12.2 9.7e-27 93.4 12.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 EB PF01683.18 KEY65821.1 - 0.00078 19.7 32.6 0.1 12.9 7.7 4.3 1 1 3 4 4 4 3 EB module PI-PLC-X PF00388.19 KEY65823.1 - 2.9e-62 208.6 0.0 4.3e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEY65823.1 - 9.4e-43 145.2 0.0 1.7e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KEY65823.1 - 1.5e-05 25.2 0.0 6.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain QWRF PF04484.12 KEY65823.1 - 3.3 7.4 6.5 5.7 6.6 6.5 1.3 1 0 0 1 1 1 0 QWRF family NRDE-2 PF08424.10 KEY65824.1 - 1.5e-100 336.5 5.6 1.3e-99 333.4 1.5 2.9 3 1 0 3 3 3 2 NRDE-2, necessary for RNA interference adh_short PF00106.25 KEY65825.1 - 3.9e-31 108.0 0.0 4.9e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY65825.1 - 1.9e-25 89.8 0.0 2.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY65825.1 - 1e-11 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KEY65825.1 - 0.0005 20.1 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEY65825.1 - 0.028 14.3 0.1 0.096 12.6 0.1 1.8 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KEY65825.1 - 0.098 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KEY65825.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KEY65825.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Urb2 PF10441.9 KEY65826.1 - 6.2e-63 212.4 0.2 6.2e-63 212.4 0.2 2.8 3 0 0 3 3 3 1 Urb2/Npa2 family Telomere_reg-2 PF10193.9 KEY65826.1 - 0.042 14.3 0.4 0.27 11.7 0.0 2.7 2 1 1 3 3 3 0 Telomere length regulation protein DUF1870 PF08965.10 KEY65826.1 - 0.12 12.4 0.0 4.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) F_actin_bind PF08919.10 KEY65826.1 - 0.29 11.3 1.6 2.1 8.5 0.5 3.0 2 0 0 2 2 2 0 F-actin binding DUF543 PF04418.12 KEY65827.1 - 5.7e-30 103.1 0.1 6.6e-30 102.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Zn_clus PF00172.18 KEY65828.1 - 0.00038 20.5 13.6 0.00067 19.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KEY65831.1 - 0.0086 16.5 3.7 1 10.0 0.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY65831.1 - 0.022 15.6 3.6 11 7.1 0.0 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger TIM PF00121.18 KEY65832.1 - 1.8e-89 299.3 0.1 2e-89 299.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.16 KEY65833.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GHL10 PF02638.15 KEY65833.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase-like 10 U1snRNP70_N PF12220.8 KEY65834.1 - 7.6e-24 84.2 6.4 1e-23 83.8 4.9 1.9 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KEY65834.1 - 5.1e-17 61.5 0.0 2.5e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY65834.1 - 4e-06 26.8 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RL10P_insert PF17777.1 KEY65835.1 - 2.8e-21 75.3 0.0 4.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KEY65835.1 - 2.5e-20 72.5 0.0 3.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 NTF2 PF02136.20 KEY65836.1 - 1.7e-21 77.0 0.1 2.8e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KEY65836.1 - 1.5e-10 40.8 0.1 2.8e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEY65836.1 - 0.00016 21.7 0.0 0.0006 19.8 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif TPR_MLP1_2 PF07926.12 KEY65840.1 - 0.02 15.0 6.5 0.038 14.1 6.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 KEY65840.1 - 0.023 15.0 1.3 0.044 14.1 0.1 2.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Amidase PF01425.21 KEY65841.1 - 1.9e-30 106.2 0.5 2.9e-30 105.6 0.5 1.1 1 0 0 1 1 1 1 Amidase Autophagy_N PF03986.13 KEY65842.1 - 7.2e-47 158.8 0.7 1.6e-46 157.7 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KEY65842.1 - 4.7e-16 58.0 0.6 9.9e-16 57.0 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KEY65842.1 - 2.4e-15 56.8 0.2 4.6e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain PBP1_TM PF14812.6 KEY65842.1 - 1.3 9.4 8.7 0.24 11.8 1.4 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCCH PF00642.24 KEY65843.1 - 5.2e-08 32.6 2.5 1e-07 31.6 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KEY65843.1 - 6.7e-08 32.3 5.3 1.2e-07 31.5 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY65843.1 - 2.8e-07 30.3 8.3 4.9e-07 29.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY65843.1 - 3.6e-07 30.1 6.8 7.4e-07 29.1 6.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY65843.1 - 6.2e-07 29.1 8.4 1.2e-06 28.3 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY65843.1 - 1.2e-06 28.4 7.6 2e-06 27.6 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KEY65843.1 - 2.9e-05 24.0 6.4 5.3e-05 23.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KEY65843.1 - 5.8e-05 23.1 3.6 5.8e-05 23.1 3.6 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KEY65843.1 - 9.9e-05 22.6 7.2 0.00018 21.8 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KEY65843.1 - 0.0002 21.1 2.6 0.00037 20.2 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KEY65843.1 - 0.01 16.0 8.1 0.025 14.7 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEY65843.1 - 0.027 14.3 5.4 0.051 13.4 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Phage_TTP_13 PF16463.5 KEY65843.1 - 0.063 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein family Harakiri PF15196.6 KEY65843.1 - 0.11 13.0 0.9 0.31 11.5 0.9 1.8 1 0 0 1 1 1 0 Activator of apoptosis harakiri zf-CCCH_2 PF14608.6 KEY65843.1 - 0.18 12.3 2.9 0.37 11.3 2.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KEY65843.1 - 0.37 11.1 3.2 0.73 10.2 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain tRNA-synt_1d PF00750.19 KEY65844.1 - 2.9e-90 302.7 0.1 6.1e-90 301.7 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEY65844.1 - 1.1e-21 77.2 0.0 2.5e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KEY65844.1 - 0.011 16.3 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Mago_nashi PF02792.14 KEY65844.1 - 0.18 11.9 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Mago nashi protein DUF3638 PF12340.8 KEY65845.1 - 7e-90 300.3 0.1 1.4e-89 299.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEY65845.1 - 3.3e-14 51.9 0.4 9.5e-14 50.5 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Mcp5_PH PF12814.7 KEY65846.1 - 5.6e-44 149.2 0.0 1.2e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KEY65846.1 - 5.5e-06 26.8 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Prophage_tail PF06605.11 KEY65846.1 - 0.091 12.0 0.5 0.17 11.1 0.5 1.4 1 0 0 1 1 1 0 Prophage endopeptidase tail DUF4559 PF15112.6 KEY65846.1 - 0.68 9.6 10.6 5 6.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) MMM1 PF10296.9 KEY65847.1 - 5.1e-07 29.1 0.5 3.1e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 DNA_pol_B PF00136.21 KEY65848.1 - 3e-101 339.4 0.0 4.8e-101 338.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEY65848.1 - 1.5e-21 76.9 0.1 1.1e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEY65848.1 - 2.1e-17 63.3 6.5 2.1e-17 63.3 6.5 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slx4 PF09494.10 KEY65848.1 - 0.16 12.0 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 Slx4 endonuclease Slu7 PF11708.8 KEY65849.1 - 2.9e-77 260.1 22.7 2.9e-77 260.1 22.7 3.2 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KEY65849.1 - 0.022 14.5 0.6 0.042 13.6 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 KEY65850.1 - 1.2e-11 44.1 0.7 1.2e-11 44.1 0.7 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KEY65850.1 - 3.2e-05 24.7 0.1 5.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4194 PF13835.6 KEY65850.1 - 0.021 14.6 1.7 0.076 12.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4194) Ribosomal_L21e PF01157.18 KEY65851.1 - 3e-46 155.4 5.7 3e-46 155.4 5.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 KEY65851.1 - 0.0034 17.2 1.5 0.045 13.6 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5486) NaeI PF09126.10 KEY65851.1 - 0.032 13.4 0.9 0.084 12.1 0.4 1.8 2 0 0 2 2 2 0 Restriction endonuclease NaeI ANTH PF07651.16 KEY65852.1 - 4.6e-78 262.0 0.0 4.6e-78 262.0 0.0 2.6 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 KEY65852.1 - 6.6e-55 185.6 8.9 6.6e-55 185.6 8.9 6.1 4 1 1 5 5 5 2 I/LWEQ domain FAM184 PF15665.5 KEY65852.1 - 0.0095 15.7 16.8 0.0095 15.7 16.8 4.6 2 2 2 4 4 4 2 Family with sequence similarity 184, A and B T2SSF PF00482.23 KEY65852.1 - 0.74 9.8 6.0 1.3 9.0 1.5 3.6 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F Surfac_D-trimer PF09006.11 KEY65852.1 - 1.5 8.7 6.3 0.19 11.7 0.3 2.8 3 1 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation MATalpha_HMGbox PF04769.12 KEY65853.1 - 5e-58 195.7 0.0 7.9e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box MAT1-1-2 PF17043.5 KEY65854.1 - 1.5e-22 80.1 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function HMG_box PF00505.19 KEY65855.1 - 1.9e-19 69.8 2.7 1.9e-19 69.8 2.7 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEY65855.1 - 4.1e-09 36.9 1.6 6.2e-09 36.3 1.6 1.2 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos PF03372.23 KEY65856.1 - 5.3e-15 55.6 0.2 8.5e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KEY65856.1 - 3.4e-07 30.3 1.6 8.6e-07 28.9 1.6 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.15 KEY65857.1 - 2.6e-49 166.4 3.7 3.1e-49 166.1 3.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 KEY65857.1 - 0.023 14.7 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) ANAPC5 PF12862.7 KEY65858.1 - 7.7e-32 109.2 2.4 7.7e-32 109.2 2.4 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_1 PF00515.28 KEY65858.1 - 0.0055 16.5 0.9 4.6 7.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat COG7 PF10191.9 KEY65858.1 - 0.018 13.3 0.2 0.24 9.6 0.0 2.1 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) TPR_10 PF13374.6 KEY65858.1 - 0.018 14.9 7.6 8.5 6.4 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65858.1 - 0.05 13.7 3.9 1.8 8.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KEY65858.1 - 0.062 13.4 0.1 0.57 10.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.14 KEY65858.1 - 0.063 13.9 9.7 6.5 7.7 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEY65858.1 - 0.064 13.6 6.0 25 5.3 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat MbeD_MobD PF04899.12 KEY65858.1 - 0.074 13.2 1.5 0.41 10.8 0.1 3.0 3 0 0 3 3 3 0 MbeD/MobD like TPR_12 PF13424.6 KEY65858.1 - 0.29 11.5 14.9 2.8 8.3 0.1 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY65858.1 - 0.54 10.8 13.6 6.5 7.3 1.9 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65858.1 - 1.2 10.1 19.4 26 6.0 0.4 7.3 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65858.1 - 3.5 8.0 12.7 1.8 8.9 0.2 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat CIA30 PF08547.12 KEY65859.1 - 1.1e-42 145.7 0.0 1.5e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Mac_assoc PF16628.5 KEY65859.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Unstructured region on maltose acetyltransferase Tim44 PF04280.15 KEY65860.1 - 1.6e-08 34.8 0.1 3.4e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Tim44-like domain Rft-1 PF04506.13 KEY65860.1 - 0.051 12.3 0.0 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Rft protein SSF PF00474.17 KEY65861.1 - 1.1e-08 34.4 31.5 9.6e-08 31.3 31.5 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.22 KEY65862.1 - 2.3e-22 78.6 0.0 9.5e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 KEY65863.1 - 2.5e-26 92.0 2.0 5.6e-11 42.9 0.4 4.0 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEY65863.1 - 1.6e-19 69.4 17.7 3.1e-05 24.2 0.1 6.1 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KEY65863.1 - 1.9e-19 67.7 6.8 0.0012 19.1 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KEY65863.1 - 2.7e-19 69.2 8.0 0.00025 21.5 0.2 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY65863.1 - 2.1e-14 53.4 6.8 1.4e-06 28.5 0.3 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KEY65863.1 - 5.7e-05 22.9 0.6 0.0002 21.1 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY65863.1 - 0.0076 16.1 1.1 0.021 14.7 1.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KEY65863.1 - 0.02 14.8 0.2 0.092 12.6 0.3 1.9 2 0 0 2 2 2 0 F-box DUF1857 PF08982.11 KEY65864.1 - 7.3e-56 188.1 0.0 8.2e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF3875 PF12991.7 KEY65864.1 - 0.083 12.9 0.0 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) Dioxygenase_C PF00775.21 KEY65865.1 - 4.2e-44 150.1 0.0 5.7e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEY65865.1 - 3e-26 91.1 0.1 4.3e-16 58.5 0.1 2.4 2 0 0 2 2 2 2 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEY65865.1 - 0.00064 19.9 0.0 0.0034 17.6 0.0 2.2 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KEY65865.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) TTR-52 PF01060.23 KEY65865.1 - 0.12 13.0 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family DUF824 PF05688.11 KEY65865.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) AdoMet_MTase PF07757.13 KEY65866.1 - 3.2e-39 133.7 0.0 7.5e-39 132.5 0.0 1.5 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KEY65866.1 - 0.012 15.6 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SUI1 PF01253.22 KEY65867.1 - 1.4e-27 96.0 4.3 1.7e-27 95.7 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Prim_Zn_Ribbon PF08273.12 KEY65868.1 - 4.4 7.7 7.0 4.2 7.7 0.5 2.7 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase SKG6 PF08693.10 KEY65871.1 - 0.0015 17.9 0.4 0.0027 17.1 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4118 PF13493.6 KEY65871.1 - 0.037 13.8 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF4448 PF14610.6 KEY65871.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Alpha_GJ PF03229.13 KEY65871.1 - 0.45 11.1 6.5 10 6.7 3.2 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Gram_pos_anchor PF00746.21 KEY65871.1 - 1 9.4 2.6 2.6 8.1 2.6 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ATP-sulfurylase PF01747.17 KEY65873.1 - 1e-87 293.0 0.0 1.8e-87 292.3 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KEY65873.1 - 5e-53 179.2 0.0 7.4e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KEY65873.1 - 6e-53 178.8 0.0 9.3e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.10 KEY65873.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KEY65873.1 - 0.14 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TRP PF06011.12 KEY65875.1 - 7.9e-106 354.3 20.0 1.1e-105 353.9 20.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEY65875.1 - 8e-36 123.5 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 ML-like domain zf-ACC PF17848.1 KEY65876.1 - 0.14 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain UPF0016 PF01169.19 KEY65877.1 - 8.9e-41 138.1 23.1 3.1e-20 72.3 8.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4131 PF13567.6 KEY65877.1 - 1.3 8.6 5.2 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.32 KEY65878.1 - 1.5e-18 66.8 21.5 3.1e-05 24.6 0.6 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65878.1 - 1.6e-05 25.1 0.0 0.038 14.3 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KEY65878.1 - 0.0016 17.1 1.4 0.037 12.6 0.1 3.2 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 KEY65878.1 - 0.044 14.3 0.0 2.1 9.0 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KEY65878.1 - 0.11 11.9 0.2 5.3 6.3 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 KEY65878.1 - 0.23 11.4 0.2 0.23 11.4 0.2 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BUD22 PF09073.10 KEY65878.1 - 4.2 6.6 10.2 6.3 6.0 10.2 1.3 1 0 0 1 1 1 0 BUD22 IBR PF01485.21 KEY65879.1 - 2.2e-10 40.6 28.5 6.6e-08 32.7 4.9 4.6 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KEY65879.1 - 0.00024 20.9 1.7 0.00024 20.9 1.7 5.1 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY65879.1 - 0.0021 18.4 4.7 0.0021 18.4 4.7 5.2 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEY65879.1 - 0.003 17.3 1.4 0.003 17.3 1.4 5.4 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KEY65880.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABATE PF07336.11 KEY65880.1 - 0.04 14.6 0.0 0.073 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative stress-induced transcription regulator CDC45 PF02724.14 KEY65880.1 - 1.5 7.0 6.6 1.7 6.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.14 KEY65880.1 - 5.8 7.4 11.7 11 6.5 11.7 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family APH PF01636.23 KEY65881.1 - 2.8e-12 47.1 0.3 6.9e-12 45.8 0.3 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY65881.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SET PF00856.28 KEY65882.1 - 5.9e-12 46.3 0.0 1.3e-11 45.2 0.0 1.6 1 1 0 1 1 1 1 SET domain CPV_Polyhedrin PF17515.2 KEY65882.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cypovirus polyhedrin CDC45 PF02724.14 KEY65883.1 - 0.64 8.2 9.2 1.5 7.0 9.2 1.6 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KEY65883.1 - 5.1 5.1 7.7 34 2.3 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi Sec3_C PF09763.9 KEY65884.1 - 8.3e-233 774.8 0.0 1.1e-232 774.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KEY65884.1 - 3.7e-28 97.5 0.0 7.3e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KEY65884.1 - 0.013 14.3 0.7 0.036 12.8 0.1 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family Sec3_C_2 PF15278.6 KEY65884.1 - 0.031 14.6 3.0 0.07 13.5 0.0 2.9 3 0 0 3 3 3 0 Sec3 exocyst complex subunit DUF2018 PF09442.10 KEY65884.1 - 0.14 13.1 0.1 0.58 11.2 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) Peptidase_S58 PF03576.14 KEY65885.1 - 3.5e-111 371.5 0.6 4e-111 371.3 0.6 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.19 KEY65886.1 - 2.9e-102 342.2 0.0 3.7e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KEY65886.1 - 9e-17 61.6 0.0 2e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KEY65886.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Catalase_C PF18011.1 KEY65886.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases Complex1_51K PF01512.17 KEY65887.1 - 3.1e-47 160.3 0.0 5e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KEY65887.1 - 2.3e-29 101.3 1.6 2.9e-29 101.0 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KEY65887.1 - 9.2e-09 35.0 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.14 KEY65888.1 - 2.6e-17 63.1 0.3 4.3e-16 59.1 0.3 2.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CUE PF02845.16 KEY65889.1 - 0.00033 20.3 0.0 0.00078 19.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.10 KEY65889.1 - 0.0015 18.9 7.9 0.0047 17.3 7.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KEY65889.1 - 0.0047 17.3 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 Smr domain UBA PF00627.31 KEY65889.1 - 0.02 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain NPC1_N PF16414.5 KEY65890.1 - 1.3e-83 280.3 5.5 2.4e-83 279.4 5.5 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KEY65890.1 - 2.6e-75 254.1 2.7 6.7e-44 150.2 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KEY65890.1 - 8.3e-50 168.6 3.7 8.3e-50 168.6 3.7 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SLATT_fungal PF18142.1 KEY65890.1 - 6.4e-32 110.1 0.0 6.4e-32 110.1 0.0 2.1 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain MMPL PF03176.15 KEY65890.1 - 3.1e-09 36.2 30.1 2.9e-05 23.2 9.8 2.4 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 KEY65890.1 - 0.0093 15.9 0.8 0.02 14.8 0.8 1.4 1 0 0 1 1 1 1 Folate receptor family YTH PF04146.15 KEY65891.1 - 6.3e-36 123.8 0.6 2.9e-35 121.7 0.2 2.3 2 1 0 2 2 2 1 YT521-B-like domain Mannosyl_trans2 PF04188.13 KEY65892.1 - 5.9e-53 180.8 5.3 9.7e-53 180.0 5.3 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) APH PF01636.23 KEY65893.1 - 2e-16 60.6 0.0 2.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.16 KEY65894.1 - 6.1e-16 58.9 0.0 2.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KEY65894.1 - 0.00061 20.5 0.1 0.0007 20.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEY65894.1 - 0.0073 16.2 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KEY65894.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEY65894.1 - 0.068 12.6 0.1 1.9 7.9 0.0 2.5 1 1 2 3 3 3 0 Prolyl oligopeptidase family MR_MLE_C PF13378.6 KEY65895.1 - 4e-58 196.6 0.0 7.1e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEY65895.1 - 0.0018 18.5 0.1 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KEY65895.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Skp1 PF01466.19 KEY65895.1 - 0.28 11.3 0.7 18 5.6 0.0 2.9 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Glyco_tranf_2_3 PF13641.6 KEY65897.1 - 4.2e-10 39.9 1.3 3e-05 24.0 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEY65897.1 - 0.00026 20.5 0.3 0.58 9.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEY65897.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 ADH_N PF08240.12 KEY65899.1 - 4.8e-25 87.6 3.0 7.7e-25 86.9 3.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY65899.1 - 1.8e-16 60.3 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY65899.1 - 2.9e-05 23.5 0.3 5.3e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY65899.1 - 0.015 14.6 0.0 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KEY65899.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.32 KEY65900.1 - 9.4e-07 29.4 6.4 2.5 9.1 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65900.1 - 3.7e-05 23.9 0.2 0.36 11.1 0.0 4.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY65900.1 - 0.0034 17.3 0.1 0.32 10.9 0.0 2.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KEY65900.1 - 0.0035 17.2 0.2 1.4e+02 2.6 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEY65900.1 - 0.0077 15.2 0.0 0.81 8.6 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CHASE5 PF17149.4 KEY65900.1 - 0.15 12.0 0.0 1.8 8.6 0.0 2.6 3 0 0 3 3 3 0 Periplasmic sensor domain found in signal transduction proteins PP2C_2 PF13672.6 KEY65900.1 - 0.25 11.0 2.6 0.59 9.7 0.0 2.5 3 1 0 3 3 3 0 Protein phosphatase 2C DUF572 PF04502.13 KEY65901.1 - 0.19 11.3 25.5 0.28 10.8 25.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PX PF00787.24 KEY65902.1 - 6.7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 PX domain EB1 PF03271.17 KEY65903.1 - 8.8e-17 61.1 1.9 1.9e-16 60.0 1.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KEY65903.1 - 2.6e-07 30.8 0.5 5e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KEY65903.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein Suppressor_APC PF11414.8 KEY65903.1 - 0.065 13.3 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Syja_N PF02383.18 KEY65903.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain DEAD PF00270.29 KEY65904.1 - 1.2e-45 155.4 0.1 2.2e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.9 KEY65904.1 - 1.6e-31 108.6 0.0 3.9e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.31 KEY65904.1 - 1.4e-29 102.7 0.2 4.5e-29 101.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KEY65904.1 - 0.008 15.0 1.8 0.014 14.2 0.2 2.1 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MlrC_C PF07171.12 KEY65904.1 - 0.11 12.7 1.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 MlrC C-terminus AMP-binding PF00501.28 KEY65905.1 - 4.5e-66 223.2 0.1 1.4e-25 89.8 0.0 4.3 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 KEY65905.1 - 0.0026 18.6 0.1 0.0055 17.5 0.1 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain PDEase_II PF02112.15 KEY65908.1 - 1.7e-53 181.9 0.0 5.6e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KEY65908.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4949 PF16307.5 KEY65908.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) Lactamase_B_2 PF12706.7 KEY65909.1 - 1.3e-18 67.2 0.2 3.3e-18 65.9 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KEY65909.1 - 4.9e-18 64.6 0.0 2.3e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KEY65909.1 - 1.2e-06 28.7 0.1 3.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily YCII PF03795.14 KEY65909.1 - 0.064 13.7 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 YCII-related domain Pkinase PF00069.25 KEY65911.1 - 5.8e-52 176.7 0.0 1.4e-51 175.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65911.1 - 3.4e-19 69.2 0.0 9.7e-19 67.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY65911.1 - 0.0034 16.7 0.3 1.4 8.2 0.1 2.4 2 0 0 2 2 2 2 Kinase-like Mtc PF03820.17 KEY65913.1 - 5e-112 374.0 0.2 5.8e-112 373.8 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PNPase_C PF12111.8 KEY65913.1 - 6.2 6.3 5.7 20 4.7 5.7 1.8 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Acetyltransf_7 PF13508.7 KEY65914.1 - 0.0056 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY65914.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Arf PF00025.21 KEY65915.1 - 2.8e-67 225.5 0.4 3.1e-67 225.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEY65915.1 - 4e-12 46.0 0.6 7.9e-07 28.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEY65915.1 - 4.6e-12 46.2 0.0 6.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEY65915.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEY65915.1 - 5.2e-09 35.8 0.0 6.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEY65915.1 - 3.1e-08 33.2 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEY65915.1 - 5.5e-08 32.9 0.0 8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY65915.1 - 0.0089 15.6 0.0 0.21 11.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KEY65915.1 - 0.05 13.1 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 KEY65915.1 - 0.074 13.0 0.2 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 KEY65915.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 KEY65916.1 - 2.4e-92 310.8 42.8 1.4e-51 176.5 29.6 6.4 4 2 3 7 7 7 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KEY65916.1 - 2.6e-11 43.3 0.0 0.0047 16.8 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat Acyltransferase PF01553.21 KEY65917.1 - 1.7e-33 115.1 0.0 2.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.9 KEY65918.1 - 5.5e-103 344.4 0.0 7.6e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KEY65918.1 - 9.3e-66 221.9 0.1 9.3e-66 221.9 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4484) SPA PF08616.10 KEY65918.1 - 2.9e-06 27.2 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KEY65918.1 - 0.00032 19.5 0.0 0.0011 17.7 0.0 1.9 2 0 0 2 2 2 1 Transport protein Avl9 DUF2001 PF09393.10 KEY65918.1 - 0.042 13.8 0.0 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube protein Importin_rep_4 PF18808.1 KEY65918.1 - 0.11 12.8 2.3 0.13 12.6 0.3 2.1 3 0 0 3 3 3 0 Importin repeat DnaJ PF00226.31 KEY65919.1 - 4.6e-16 58.7 0.6 1.1e-15 57.5 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KEY65919.1 - 1.5e-12 47.3 0.0 1.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain RRN3 PF05327.11 KEY65919.1 - 0.94 7.9 2.9 1.4 7.3 2.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3336 PF11815.8 KEY65920.1 - 1.1e-49 167.6 8.3 1.7e-49 167.1 8.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEY65920.1 - 4.8e-18 66.1 0.3 1.3e-17 64.6 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase CHAD PF05235.14 KEY65920.1 - 0.0097 15.9 0.5 0.018 15.1 0.5 1.4 1 0 0 1 1 1 1 CHAD domain Arf PF00025.21 KEY65921.1 - 8.6e-66 220.7 0.0 9.6e-66 220.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEY65921.1 - 4.7e-10 39.2 0.1 1.6e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEY65921.1 - 2.1e-07 31.2 0.0 7.1e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEY65921.1 - 2.3e-07 30.6 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KEY65921.1 - 4.3e-07 29.5 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEY65921.1 - 1.2e-06 28.6 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEY65921.1 - 3.4e-05 23.3 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEY65921.1 - 0.033 13.7 0.1 1.2 8.6 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 KEY65922.1 - 3.2e-167 557.4 23.2 3.2e-167 557.4 23.2 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 KEY65922.1 - 1.4 8.9 20.9 0.23 11.4 16.8 1.8 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KEY65922.1 - 7 4.7 15.6 14 3.7 15.6 1.4 1 0 0 1 1 1 0 Nop14-like family ATP-synt_DE_N PF02823.16 KEY65923.1 - 6.6e-16 58.0 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Vps39_2 PF10367.9 KEY65926.1 - 6.5e-06 26.6 0.0 2.1e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KEY65926.1 - 0.0049 17.1 0.2 0.019 15.3 0.0 2.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KEY65926.1 - 0.052 13.4 0.0 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS CASP_C PF08172.12 KEY65927.1 - 2.7e-94 315.2 19.3 3.7e-94 314.8 0.0 3.3 4 0 0 4 4 4 1 CASP C terminal bZIP_2 PF07716.15 KEY65927.1 - 0.016 15.3 2.4 0.016 15.3 2.4 8.1 9 1 0 9 9 8 0 Basic region leucine zipper LMBR1 PF04791.16 KEY65927.1 - 0.034 13.1 0.0 0.034 13.1 0.0 3.1 2 1 0 2 2 1 0 LMBR1-like membrane protein Filament PF00038.21 KEY65927.1 - 0.085 12.4 49.9 0.052 13.1 2.8 4.5 2 1 2 5 5 5 0 Intermediate filament protein SKA1 PF07160.12 KEY65927.1 - 0.1 12.4 24.7 0.85 9.4 10.7 4.6 3 1 0 4 4 4 0 Spindle and kinetochore-associated protein 1 TolA_bind_tri PF16331.5 KEY65927.1 - 0.26 11.4 33.9 1.4 9.0 0.7 6.1 6 0 0 6 6 6 0 TolA binding protein trimerisation NAD_binding_1 PF00175.21 KEY65927.1 - 0.27 11.9 2.0 4.8 7.9 0.0 3.5 3 1 0 3 3 3 0 Oxidoreductase NAD-binding domain SlyX PF04102.12 KEY65927.1 - 0.38 11.4 33.7 0.47 11.1 0.0 6.5 6 1 1 7 7 7 0 SlyX TPR_MLP1_2 PF07926.12 KEY65927.1 - 0.73 9.9 63.9 0.37 10.9 2.9 7.0 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KEY65927.1 - 2.1 8.8 49.6 0.73 10.2 19.1 4.4 2 2 2 4 4 4 0 Fez1 DUF4618 PF15397.6 KEY65927.1 - 5.5 6.3 35.3 6.2 6.2 0.9 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 KEY65927.1 - 8.7 6.9 64.1 0.53 10.8 13.0 6.0 2 1 4 6 6 6 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KEY65927.1 - 8.9 7.3 49.8 0.17 12.8 1.9 5.7 5 1 0 6 6 6 0 cGMP-dependent protein kinase interacting domain DUF3455 PF11937.8 KEY65928.1 - 7.9e-42 143.3 0.1 1.1e-41 142.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KEY65928.1 - 0.00037 20.6 2.7 0.0078 16.4 1.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) F-box PF00646.33 KEY65929.1 - 0.002 17.9 0.0 0.0076 16.1 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY65929.1 - 0.096 12.6 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like Ribosomal_L22 PF00237.19 KEY65930.1 - 3.7e-40 136.3 0.1 5.5e-40 135.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KEY65930.1 - 0.084 13.2 0.0 0.097 13.0 0.0 1.4 1 1 0 1 1 1 0 Lamin Tail Domain Fibrillarin PF01269.17 KEY65931.1 - 2.3e-98 327.8 0.0 2.8e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KEY65931.1 - 0.00012 21.9 0.0 0.00025 20.8 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KEY65931.1 - 0.045 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KEY65932.1 - 1.1e-38 133.2 0.0 1.4e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KEY65933.1 - 3.3e-43 147.8 0.0 4.6e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KEY65933.1 - 8e-10 39.3 0.0 2.1e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 KEY65934.1 - 3.1e-11 43.6 0.0 3.9e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.15 KEY65935.1 - 1.2e-78 263.3 0.0 1.6e-76 256.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.23 KEY65936.1 - 5e-06 26.2 0.1 1.4e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KEY65936.1 - 0.00036 21.1 0.0 0.00036 21.1 0.0 2.5 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Pex14_N PF04695.13 KEY65936.1 - 0.0039 17.8 1.4 0.0039 17.8 1.4 5.3 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rad60-SLD_2 PF13881.6 KEY65936.1 - 0.0083 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C12 PF01088.21 KEY65937.1 - 1.1e-67 227.9 0.0 1.4e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KEY65937.1 - 4.4e-10 39.3 1.6 4.4e-10 39.3 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Xan_ur_permease PF00860.20 KEY65938.1 - 5.3e-26 91.2 29.8 2.6e-25 89.0 29.1 2.4 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 KEY65938.1 - 0.25 11.7 15.2 0.032 14.6 3.9 3.0 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Methyltransf_25 PF13649.6 KEY65939.1 - 0.002 18.8 0.0 0.0059 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY65939.1 - 0.0034 18.1 0.0 0.34 11.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65939.1 - 0.0081 16.8 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY65939.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Dicty_CAR PF05462.11 KEY65940.1 - 9.7e-09 34.8 6.9 9.7e-09 34.8 6.9 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KEY65940.1 - 7.9e-08 31.9 1.9 1.2e-07 31.4 1.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KEY65940.1 - 1.8e-07 31.1 8.7 3.8e-07 30.1 8.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KEY65940.1 - 0.0078 15.6 3.3 0.012 15.0 3.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GAS PF13851.6 KEY65942.1 - 0.73 9.1 4.3 2.1 7.6 0.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding adh_short_C2 PF13561.6 KEY65944.1 - 2.7e-48 164.6 0.2 3.3e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY65944.1 - 1.6e-42 145.2 0.3 2.3e-42 144.7 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY65944.1 - 2.8e-10 40.4 0.1 4.6e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 KR domain N2227 PF07942.12 KEY65945.1 - 2.6e-99 331.8 0.0 3.2e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KEY65945.1 - 0.0015 18.3 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY65945.1 - 0.0033 18.2 0.1 0.021 15.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY65945.1 - 0.0056 17.3 0.0 0.061 14.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PAC4 PF16093.5 KEY65946.1 - 1.1e-21 76.8 0.5 1.5e-21 76.4 0.5 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_EZ PF13513.6 KEY65947.1 - 3.7e-34 116.7 12.0 5.6e-15 55.5 0.0 10.3 10 0 0 10 10 9 6 HEAT-like repeat HEAT PF02985.22 KEY65947.1 - 1.6e-24 83.9 7.9 0.0001 22.2 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 KEY65947.1 - 1.7e-17 63.6 1.3 0.0037 17.6 0.0 7.3 5 2 1 6 6 6 3 HEAT repeats IBN_N PF03810.19 KEY65947.1 - 1.2e-09 37.9 2.7 2.2e-06 27.5 0.2 4.5 3 1 1 4 4 4 2 Importin-beta N-terminal domain Cnd1 PF12717.7 KEY65947.1 - 1.7e-08 34.7 0.0 0.034 14.2 0.0 5.0 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KEY65947.1 - 2.1e-08 33.7 4.4 0.11 11.6 0.0 5.5 5 1 1 6 6 6 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KEY65947.1 - 6.7e-08 33.0 0.0 0.046 14.3 0.0 6.1 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KEY65947.1 - 2.1e-05 24.2 0.1 12 5.4 0.0 6.6 6 2 0 7 7 7 1 CLASP N terminal Arm PF00514.23 KEY65947.1 - 0.00083 19.3 4.3 2.6 8.2 0.0 6.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KEY65947.1 - 0.014 15.6 0.0 0.33 11.1 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KEY65947.1 - 0.037 13.3 0.1 5.2 6.3 0.1 3.5 2 2 0 2 2 2 0 V-ATPase subunit H HEAT_PBS PF03130.16 KEY65947.1 - 0.15 12.8 10.5 1.2 10.0 0.0 6.1 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat DUF3437 PF11919.8 KEY65947.1 - 0.15 11.9 0.0 8.9 6.3 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) TnpV PF14198.6 KEY65947.1 - 0.27 11.3 1.0 74 3.4 0.0 3.3 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Zn_clus PF00172.18 KEY65949.1 - 2.3e-07 30.8 12.1 3.5e-07 30.3 12.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY65949.1 - 1.3e-06 27.5 0.3 1.3e-06 27.5 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain FliG_M PF14841.6 KEY65949.1 - 0.014 15.6 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain SPRY PF00622.28 KEY65950.1 - 4.8e-18 65.4 0.0 8.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain CBFB_NFYA PF02045.15 KEY65952.1 - 3.6e-28 98.0 5.3 6.8e-28 97.1 5.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B UBA2_C PF16195.5 KEY65952.1 - 0.019 15.6 5.1 0.019 15.6 5.1 2.0 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Hus1 PF04005.12 KEY65952.1 - 0.07 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 KEY65952.1 - 4.2 7.2 16.2 5.5 6.9 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_12 PF13424.6 KEY65953.1 - 2.1e-113 370.8 1.3 4.1e-19 68.6 0.0 8.0 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 KEY65953.1 - 5.9e-102 331.2 0.1 9.5e-13 47.6 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KEY65953.1 - 3.5e-29 98.7 6.0 0.0023 17.8 0.0 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KEY65953.1 - 7.3e-25 87.3 0.0 0.029 15.0 0.0 8.8 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_4 PF07721.14 KEY65953.1 - 1.1e-22 78.2 0.4 0.84 10.4 0.0 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEY65953.1 - 2.2e-20 71.5 0.7 0.17 11.8 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEY65953.1 - 1.4e-19 68.5 8.0 0.4 10.9 0.0 8.9 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KEY65953.1 - 9.7e-17 60.1 0.9 0.28 11.6 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEY65953.1 - 1.2e-16 59.4 3.4 0.84 10.0 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY65953.1 - 4.4e-16 59.2 6.3 5.1e-09 36.0 0.4 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 KEY65953.1 - 1e-12 48.4 0.0 0.33 11.5 0.0 7.8 5 1 2 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY65953.1 - 6.5e-11 42.1 4.7 16 6.7 0.0 9.1 8 1 1 9 9 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 KEY65953.1 - 2.9e-10 39.7 0.0 5.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.20 KEY65953.1 - 1.1e-07 31.7 2.9 3.1 8.3 0.0 7.2 8 0 0 8 8 8 1 PPR repeat Rbsn PF11464.8 KEY65953.1 - 7.8e-06 25.5 0.6 76 3.2 0.0 6.9 8 0 0 8 8 7 0 Rabenosyn Rab binding domain NACHT PF05729.12 KEY65953.1 - 2.6e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.6 KEY65953.1 - 8e-05 23.0 6.4 4.4 8.2 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KEY65953.1 - 0.00039 20.4 0.0 0.85 9.7 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEY65953.1 - 0.00079 19.9 0.0 0.0038 17.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain ANAPC3 PF12895.7 KEY65953.1 - 0.0053 16.9 0.0 6.8 7.0 0.0 4.9 1 1 4 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 KEY65953.1 - 0.026 14.0 0.1 0.31 10.5 0.0 2.5 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like PPR_2 PF13041.6 KEY65953.1 - 0.056 13.6 1.3 13 6.0 0.1 4.4 4 0 0 4 4 4 0 PPR repeat family DUF1897 PF09005.10 KEY65953.1 - 0.24 10.9 10.5 5.9 6.5 0.1 5.9 7 0 0 7 7 7 0 Domain of unknown function (DUF1897) PNP_UDP_1 PF01048.20 KEY65955.1 - 1.6e-16 60.3 2.5 1.3e-15 57.3 2.5 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ses_B PF17046.5 KEY65955.1 - 0.017 15.1 3.0 0.036 14.0 3.0 1.5 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein APH PF01636.23 KEY65957.1 - 1.5e-44 152.8 0.0 2e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEY65957.1 - 8.6e-06 25.3 0.1 3.8e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 KEY65957.1 - 0.00017 20.9 0.0 0.00041 19.6 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.25 KEY65957.1 - 0.0011 18.4 0.0 0.049 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KEY65957.1 - 0.011 15.4 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KEY65957.1 - 0.023 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KEY65957.1 - 0.055 12.8 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KEY65957.1 - 0.061 12.2 0.0 0.21 10.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) PspC PF04024.12 KEY65957.1 - 0.11 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 PspC domain MTS PF05175.14 KEY65958.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PKD_channel PF08016.12 KEY65958.1 - 0.097 11.3 3.6 3.8 6.1 0.6 2.2 2 0 0 2 2 2 0 Polycystin cation channel LSM PF01423.22 KEY65959.1 - 9.8e-18 63.6 0.2 1.3e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEY65959.1 - 0.00031 20.8 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 KEY65959.1 - 0.022 15.3 2.4 0.032 14.8 2.4 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Cullin PF00888.22 KEY65960.1 - 1.7e-193 644.7 1.9 2.5e-193 644.1 1.9 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEY65960.1 - 3.6e-28 97.4 0.9 1.1e-27 95.8 0.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain CYTL1 PF15153.6 KEY65960.1 - 0.086 12.8 0.0 12 5.8 0.0 3.0 2 1 0 2 2 2 0 Cytokine-like protein 1 FAA_hydrolase PF01557.18 KEY65961.1 - 4.8e-52 176.8 0.0 5.5e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KEY65962.1 - 4.8e-63 211.3 0.0 5.9e-63 211.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KEY65962.1 - 2.8e-06 27.0 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KEY65962.1 - 0.00068 19.3 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KEY65962.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.7 KEY65962.1 - 0.0073 16.3 2.6 0.014 15.4 2.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-HC5HC2H_2 PF13832.6 KEY65962.1 - 0.0095 16.1 0.5 0.016 15.3 0.5 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Cupin_4 PF08007.12 KEY65962.1 - 0.054 13.0 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Nudix_N_2 PF14803.6 KEY65962.1 - 0.073 13.0 1.4 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal ARD PF03079.14 KEY65962.1 - 0.14 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family C1_1 PF00130.22 KEY65962.1 - 0.14 12.1 1.9 3.6 7.5 0.3 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KEY65962.1 - 0.34 11.1 2.1 0.34 11.1 0.4 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Ctr PF04145.15 KEY65963.1 - 1.2e-29 103.9 15.5 6.1e-28 98.3 15.5 2.0 1 1 0 1 1 1 1 Ctr copper transporter family LPG_synthase_TM PF03706.13 KEY65963.1 - 0.002 17.7 3.3 0.0027 17.3 3.3 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region NUDIX PF00293.28 KEY65964.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain SF3b1 PF08920.10 KEY65965.1 - 1.9e-25 89.6 9.2 1.9e-25 89.6 9.2 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KEY65965.1 - 3.5e-14 52.9 1.6 0.016 15.7 0.0 8.1 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KEY65965.1 - 2.9e-11 43.6 7.6 0.1 13.0 0.1 7.8 5 3 2 9 9 9 4 HEAT repeats HEAT PF02985.22 KEY65965.1 - 5.2e-09 35.6 9.5 1.8 9.0 0.0 9.2 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 KEY65965.1 - 4.2e-06 26.9 1.8 5.8 6.9 0.0 6.3 6 2 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEY65965.1 - 2e-05 25.1 0.3 1.1 9.9 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KEY65965.1 - 4e-05 22.4 0.5 0.019 13.5 0.1 3.3 3 1 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 KEY65965.1 - 8.5e-05 22.5 0.7 0.017 15.0 0.0 4.5 4 1 0 5 5 5 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KEY65965.1 - 0.00014 21.6 0.3 0.95 9.1 0.0 4.3 4 1 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 KEY65965.1 - 0.0046 16.9 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KEY65965.1 - 0.0092 15.6 0.2 1.8 8.0 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal DRIM PF07539.12 KEY65965.1 - 0.035 12.4 0.2 8.3 4.6 0.0 3.9 2 1 0 2 2 2 0 Down-regulated in metastasis MMS19_C PF12460.8 KEY65965.1 - 0.062 12.4 0.0 4.9 6.2 0.0 3.4 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal zf-H2C2_2 PF13465.6 KEY65966.1 - 5e-09 36.2 14.2 4.8e-05 23.6 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KEY65966.1 - 4.6e-08 33.1 18.6 2.2e-05 24.6 4.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KEY65966.1 - 7.2e-06 26.2 1.3 1.8e-05 25.0 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KEY65966.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KEY65966.1 - 0.00039 21.0 10.8 0.0013 19.4 3.2 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY65966.1 - 0.00057 20.1 4.2 0.00074 19.7 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KEY65966.1 - 0.046 14.0 2.4 0.059 13.7 1.4 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KEY65966.1 - 0.093 12.5 7.4 2.1 8.2 0.6 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KEY65966.1 - 0.6 10.1 4.8 12 5.9 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Lactococcin_972 PF09683.10 KEY65966.1 - 1.5 9.4 7.0 5.8 7.6 1.0 2.9 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) Rax2 PF12768.7 KEY65969.1 - 4.1e-72 242.1 0.0 1.2e-70 237.3 0.0 3.0 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DUF1668 PF07893.13 KEY65969.1 - 0.0036 16.7 0.0 0.77 9.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) YAF2_RYBP PF17219.3 KEY65969.1 - 0.12 12.0 0.1 0.47 10.1 0.1 2.0 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif SNase PF00565.17 KEY65970.1 - 2.2e-25 89.2 0.0 3.3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.14 KEY65971.1 - 1.8e-104 348.7 0.4 2.2e-104 348.4 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 KEY65972.1 - 3.4e-46 154.3 26.6 2.1e-05 25.2 0.1 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY65972.1 - 2.5e-20 72.5 7.4 0.0028 17.9 0.0 9.7 6 2 3 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KEY65972.1 - 4e-19 68.9 0.3 7.8e-19 68.0 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KEY65972.1 - 4.3e-07 29.2 0.1 0.021 13.8 0.0 4.3 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEY65972.1 - 6.8e-05 21.7 0.2 0.98 8.0 0.0 4.5 6 0 0 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KEY65972.1 - 0.00018 20.9 0.0 4.4 6.5 0.0 3.7 3 0 0 3 3 3 3 WD40-like domain eIF2A PF08662.11 KEY65972.1 - 0.0014 18.6 0.2 1.5 8.7 0.1 4.2 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KEY65972.1 - 0.0033 16.2 0.9 3.4 6.3 0.0 3.4 2 1 0 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.6 KEY65972.1 - 0.07 12.4 0.1 0.78 9.0 0.0 2.4 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 KEY65972.1 - 0.16 11.7 2.1 3.3 7.4 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split LSM PF01423.22 KEY65973.1 - 2.8e-18 65.3 0.4 3.7e-18 65.0 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KEY65973.1 - 0.0031 17.1 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Hfq protein AEP1 PF17049.5 KEY65973.1 - 0.021 13.9 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 SM-ATX PF14438.6 KEY65973.1 - 0.034 14.3 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DRMBL PF07522.14 KEY65974.1 - 4.4e-34 117.0 0.0 7.9e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KEY65974.1 - 2.4e-08 33.7 0.0 5.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNF220 PF15926.5 KEY65974.1 - 0.04 13.5 0.7 0.08 12.6 0.1 1.9 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Pkinase PF00069.25 KEY65976.1 - 2e-55 188.0 0.0 2.6e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65976.1 - 2.1e-43 148.5 0.0 2.9e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY65976.1 - 3.4e-05 23.0 0.1 0.0056 15.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KEY65976.1 - 0.0045 16.9 0.0 0.025 14.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY65976.1 - 0.012 14.9 0.0 0.089 12.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KEY65976.1 - 0.21 10.3 0.1 0.5 9.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Telomere_reg-2 PF10193.9 KEY65977.1 - 1.5e-34 118.7 0.0 3.3e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.21 KEY65978.1 - 2.3e-63 213.8 0.1 3.5e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KEY65978.1 - 5.6e-31 106.5 0.1 9.1e-31 105.9 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KEY65978.1 - 5.8e-05 23.6 0.3 0.00053 20.5 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain E1_UFD PF09358.10 KEY65978.1 - 0.032 14.9 0.1 0.1 13.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin fold domain NAD_binding_9 PF13454.6 KEY65978.1 - 0.075 13.0 1.0 0.21 11.6 0.1 2.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KEY65978.1 - 0.19 11.8 1.0 0.94 9.5 0.0 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase RNA_pol_A_bac PF01000.26 KEY65979.1 - 1.1e-26 93.4 0.0 2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEY65979.1 - 1e-19 69.7 0.0 1.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUP214 PF16755.5 KEY65980.1 - 0.00044 19.6 0.0 0.0034 16.7 0.0 2.2 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KEY65980.1 - 0.0069 16.7 0.0 0.059 13.7 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY65980.1 - 0.11 13.4 0.2 0.43 11.5 0.2 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF501 PF04417.12 KEY65980.1 - 8.5 6.2 5.3 1.2 8.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Proteasome PF00227.26 KEY65981.1 - 2e-46 157.9 0.0 2.5e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KEY65981.1 - 1.2e-12 47.0 0.2 1.2e-12 47.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sel1 PF08238.12 KEY65982.1 - 1.1e-10 41.8 9.5 0.011 16.4 0.4 3.9 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KEY65983.1 - 9.8e-87 290.4 0.0 2.8e-86 288.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEY65983.1 - 1.2e-29 102.4 0.0 2.3e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5105 PF17118.5 KEY65984.1 - 0.13 12.1 0.4 0.16 11.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) CSTF2_hinge PF14327.6 KEY65985.1 - 2.3e-32 111.3 0.6 2.3e-32 111.3 0.6 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KEY65985.1 - 3.1e-20 71.8 0.0 4.9e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KEY65985.1 - 2.6e-11 42.9 8.2 2.6e-11 42.9 8.2 3.6 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KEY65985.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 KEY65985.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 CorA PF01544.18 KEY65986.1 - 2.5e-38 132.1 0.4 1.1e-37 129.9 0.4 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Guanylate_kin PF00625.21 KEY65986.1 - 0.15 11.8 0.3 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 Guanylate kinase CBF PF03914.17 KEY65987.1 - 4.8e-34 117.9 0.6 1.2e-33 116.5 0.1 2.0 2 0 0 2 2 2 1 CBF/Mak21 family GvpL_GvpF PF06386.11 KEY65987.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Mt_ATP-synt_B PF05405.14 KEY65988.1 - 1.4e-54 184.1 6.8 1.7e-54 183.8 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virul_Fac PF10139.9 KEY65988.1 - 0.009 14.3 3.4 0.011 14.0 3.4 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor Taxilin PF09728.9 KEY65988.1 - 0.13 11.4 10.4 0.16 11.1 10.4 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein MSC PF09402.10 KEY65989.1 - 1.8e-117 392.6 0.0 2.3e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KEY65989.1 - 1.2e-13 50.5 0.0 2.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KEY65989.1 - 0.042 13.4 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein CysG_dimeriser PF10414.9 KEY65989.1 - 1.4 8.7 4.4 0.66 9.7 0.1 2.7 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region FAD_binding_3 PF01494.19 KEY65990.1 - 1.8e-24 86.7 0.1 5.8e-23 81.7 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KEY65990.1 - 1.3e-05 24.5 0.7 0.011 14.8 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KEY65990.1 - 4.9e-05 23.1 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KEY65990.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KEY65990.1 - 0.007 15.6 0.0 0.035 13.3 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEY65990.1 - 0.0072 15.2 0.0 2.6 6.8 0.0 3.1 2 1 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 KEY65990.1 - 0.017 14.3 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KEY65990.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY65990.1 - 0.032 14.5 0.1 0.09 13.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEY65990.1 - 0.037 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Complex1_49kDa PF00346.19 KEY65991.1 - 5.2e-124 412.7 0.0 7.1e-124 412.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KEY65991.1 - 0.0084 15.1 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Zn_clus PF00172.18 KEY65992.1 - 0.031 14.4 2.9 0.05 13.7 2.9 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KEY65993.1 - 9e-29 100.6 0.0 2.3e-13 50.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY65993.1 - 7.5e-09 35.2 0.0 0.00074 18.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEY65993.1 - 0.094 12.6 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEY65993.1 - 0.18 11.1 0.0 0.44 9.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallopep PF12044.8 KEY65994.1 - 1.4e-127 425.9 0.0 1.7e-127 425.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KEY65994.1 - 0.0046 17.5 0.2 0.022 15.3 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KEY65994.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 OTT_1508_deam PF14441.6 KEY65996.1 - 2.5e-17 62.6 0.8 4.8e-17 61.7 0.8 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3638 PF12340.8 KEY65997.1 - 1.1e-94 316.0 0.8 2.3e-94 314.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEY65997.1 - 5.2e-17 60.9 0.4 5.2e-17 60.9 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) ABC2_membrane PF01061.24 KEY65998.1 - 4.7e-79 264.7 54.0 2e-42 145.0 18.9 3.6 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KEY65998.1 - 8.8e-37 124.9 5.9 3.4e-30 103.8 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KEY65998.1 - 1.3e-31 109.9 0.2 3.1e-15 56.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.6 KEY65998.1 - 3.3e-14 53.2 0.3 3.3e-14 53.2 0.3 2.6 3 0 0 3 3 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEY65998.1 - 3.2e-12 46.2 37.9 5.2e-09 35.7 12.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KEY65998.1 - 1.9e-06 28.3 0.1 0.0002 21.8 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY65998.1 - 6e-06 26.3 0.0 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_25 PF13481.6 KEY65998.1 - 2.5e-05 23.9 0.1 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEY65998.1 - 3.4e-05 23.8 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEY65998.1 - 0.00022 21.8 0.0 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY65998.1 - 0.00032 21.0 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEY65998.1 - 0.00036 20.2 0.1 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KEY65998.1 - 0.0006 20.3 0.0 0.034 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY65998.1 - 0.0009 18.9 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KEY65998.1 - 0.0017 18.5 4.6 0.02 15.0 0.0 3.0 4 0 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.23 KEY65998.1 - 0.0019 18.3 0.2 0.24 11.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KEY65998.1 - 0.0024 18.1 2.8 0.0046 17.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KEY65998.1 - 0.004 17.1 0.2 0.24 11.3 0.1 2.9 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 KEY65998.1 - 0.0047 16.9 0.2 0.23 11.5 0.2 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KEY65998.1 - 0.0047 17.3 0.2 1.2 9.5 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KEY65998.1 - 0.0075 15.4 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 KEY65998.1 - 0.0082 16.7 2.8 0.016 15.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KEY65998.1 - 0.0086 15.8 0.1 0.59 9.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KEY65998.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_19 PF13245.6 KEY65998.1 - 0.19 12.0 0.2 27 5.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain GET2 PF08690.10 KEY65998.1 - 0.31 10.7 4.0 2.1 7.9 2.3 2.5 2 0 0 2 2 2 0 GET complex subunit GET2 Vpu PF00558.19 KEY65998.1 - 0.54 10.1 2.8 0.57 10.0 0.2 2.4 2 0 0 2 2 2 0 Vpu protein E1-E2_ATPase PF00122.20 KEY65999.1 - 5.3e-42 143.4 2.2 3.7e-41 140.6 0.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY65999.1 - 3e-35 121.6 5.6 3e-35 121.6 5.6 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY65999.1 - 2.2e-24 86.9 0.0 4.8e-13 49.9 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY65999.1 - 1.4e-14 53.9 0.0 3.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEY65999.1 - 4.5e-13 48.7 0.0 1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY65999.1 - 0.01 15.6 0.4 0.035 13.9 0.2 2.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY65999.1 - 0.069 13.5 0.0 1.1 9.7 0.0 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_S17 PF00366.20 KEY65999.1 - 0.14 12.3 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S17 DUF2157 PF09925.9 KEY65999.1 - 0.18 11.6 10.9 0.12 12.1 0.5 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Spherulin4 PF12138.8 KEY66001.1 - 8.5e-47 159.8 2.1 1e-46 159.6 2.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 CDH-cyt PF16010.5 KEY66002.1 - 7e-51 172.5 0.0 1.3e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KEY66002.1 - 2.5e-28 99.3 0.0 5.2e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY66002.1 - 2.9e-21 76.5 0.1 5.8e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY66002.1 - 6.9e-11 41.9 0.3 5.1e-06 25.8 0.4 2.6 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 KEY66002.1 - 1.1e-05 25.0 3.7 2.6e-05 23.8 1.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEY66002.1 - 8.9e-05 21.7 1.1 0.0001 21.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEY66002.1 - 0.00014 20.7 0.6 0.00014 20.7 0.6 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 KEY66002.1 - 0.00057 19.2 0.6 0.0017 17.6 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY66002.1 - 0.001 18.2 0.3 0.0019 17.3 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEY66002.1 - 0.0024 17.1 0.3 0.0049 16.1 0.3 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KEY66002.1 - 0.006 16.2 8.1 0.059 12.9 8.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY66002.1 - 0.0076 15.5 0.9 0.013 14.7 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY66002.1 - 0.008 16.4 1.5 0.019 15.2 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEY66002.1 - 0.017 14.0 0.7 0.026 13.4 0.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KEY66002.1 - 0.022 15.3 0.4 0.63 10.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY66002.1 - 0.36 10.1 1.8 0.89 8.7 1.8 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_16 PF13191.6 KEY66003.1 - 6.7e-07 29.9 0.1 4.4e-06 27.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY66003.1 - 0.00019 21.7 0.1 0.00064 20.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEY66003.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KEY66003.1 - 0.016 15.1 0.1 0.058 13.3 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KEY66003.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KEY66003.1 - 0.034 13.7 0.0 0.093 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KEY66003.1 - 0.039 13.3 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KEY66003.1 - 0.062 13.0 0.2 0.85 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KEY66003.1 - 0.08 12.9 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 KEY66003.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 KEY66003.1 - 0.15 12.5 0.7 1.1 9.7 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEY66003.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FTA2 PF13095.6 KEY66004.1 - 0.08 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BTB PF00651.31 KEY66005.1 - 0.0087 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PTPS PF01242.19 KEY66005.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Lipase_GDSL_2 PF13472.6 KEY66006.1 - 1.3e-13 51.7 0.1 2e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 KEY66006.1 - 1.8e-06 27.8 6.3 5e-06 26.4 6.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KEY66006.1 - 2.6e-05 24.3 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase EHN PF06441.12 KEY66007.1 - 6.1e-36 123.1 0.1 6.1e-36 123.1 0.1 1.9 2 1 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEY66007.1 - 0.00085 19.0 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Mrr_cat PF04471.12 KEY66007.1 - 0.19 11.8 0.0 0.5 10.4 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease AAA PF00004.29 KEY66008.1 - 3.3e-19 69.6 0.0 8.2e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY66008.1 - 3.5e-05 24.3 0.0 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEY66008.1 - 0.004 17.2 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY66008.1 - 0.0053 17.0 0.1 0.036 14.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY66008.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEY66008.1 - 0.052 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Clr5 PF14420.6 KEY66009.1 - 2.8e-13 49.9 3.1 8.7e-13 48.3 3.1 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KEY66009.1 - 5.5e-08 33.0 14.2 1.9e-06 28.1 1.7 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY66009.1 - 9.2e-05 22.2 4.1 0.22 11.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY66009.1 - 0.00028 20.8 1.8 0.11 12.7 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY66009.1 - 0.0032 17.4 1.6 0.39 10.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY66009.1 - 0.039 14.5 0.1 0.039 14.5 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY66009.1 - 0.27 11.2 3.6 0.45 10.4 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY66009.1 - 0.41 11.6 19.4 5.4 8.1 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Zn_clus PF00172.18 KEY66010.1 - 8.9e-08 32.1 6.7 2e-07 31.0 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHO4 PF01384.20 KEY66011.1 - 1.5e-112 376.0 17.6 1.7e-112 375.8 17.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family AA_permease PF00324.21 KEY66012.1 - 3.4e-120 401.9 32.2 3.8e-120 401.7 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY66012.1 - 5.8e-32 111.1 36.9 7e-32 110.8 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.24 KEY66013.1 - 1.8e-39 135.6 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Cutinase PF01083.22 KEY66014.1 - 1.6e-28 99.8 0.1 1.6e-28 99.8 0.1 1.9 2 0 0 2 2 2 1 Cutinase PAP1 PF08601.10 KEY66014.1 - 0.026 14.2 7.8 0.034 13.9 7.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PE-PPE PF08237.11 KEY66014.1 - 0.065 12.8 2.4 0.074 12.6 0.0 2.1 2 1 0 2 2 2 0 PE-PPE domain SOG2 PF10428.9 KEY66014.1 - 0.099 11.8 10.4 0.12 11.6 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KEY66014.1 - 0.77 8.5 6.1 1.1 8.0 6.1 1.1 1 0 0 1 1 1 0 Presenilin PARM PF17061.5 KEY66014.1 - 2.2 8.4 28.3 3.2 7.8 28.3 1.2 1 0 0 1 1 1 0 PARM DUF936 PF06075.12 KEY66014.1 - 5.9 5.7 12.7 8 5.2 12.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) His_Phos_1 PF00300.22 KEY66015.1 - 5.5e-26 91.5 0.8 6.1e-25 88.1 0.8 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3659 PF12396.8 KEY66016.1 - 3.9e-112 366.2 61.4 1.4e-23 82.5 2.2 7.0 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) Clavanin PF05452.11 KEY66016.1 - 0.083 13.1 1.6 1.8 8.8 0.2 3.6 3 0 0 3 3 3 0 Clavanin Cor1 PF04803.12 KEY66016.1 - 0.14 12.3 1.2 0.42 10.8 1.2 1.8 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Syntaxin_2 PF14523.6 KEY66016.1 - 5.2 7.5 7.6 5 7.6 0.1 4.0 4 1 1 5 5 5 0 Syntaxin-like protein DUF3659 PF12396.8 KEY66017.1 - 2.2e-25 88.3 14.0 6.5e-15 54.8 1.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3659) Pex14_N PF04695.13 KEY66017.1 - 0.39 11.4 10.6 0.11 13.1 7.7 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KEY66017.1 - 0.99 9.0 9.7 1.4 8.5 9.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.9 KEY66018.1 - 0.16 12.0 9.7 0.2 11.7 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pec_lyase_C PF00544.19 KEY66021.1 - 1.7e-29 102.9 14.3 2.9e-18 66.2 4.8 2.3 1 1 1 2 2 2 2 Pectate lyase Phage_attach PF05354.11 KEY66021.1 - 0.031 14.2 0.3 0.67 9.9 0.0 2.4 2 1 0 2 2 2 0 Phage Head-Tail Attachment FAD_binding_4 PF01565.23 KEY66022.1 - 4.3e-13 49.2 0.0 6.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain adh_short_C2 PF13561.6 KEY66023.1 - 3.5e-56 190.4 0.1 4.3e-56 190.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66023.1 - 2.1e-45 154.6 0.0 2.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66023.1 - 2.4e-15 56.9 0.2 3.3e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66023.1 - 4.3e-05 23.1 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY66023.1 - 0.03 13.4 0.3 0.043 12.9 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain HATPase_c PF02518.26 KEY66023.1 - 0.052 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAGA-Tad1 PF12767.7 KEY66023.1 - 0.063 13.0 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GDP_Man_Dehyd PF16363.5 KEY66023.1 - 0.066 12.6 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY66023.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lactamase_B_2 PF12706.7 KEY66024.1 - 8.1e-13 48.3 0.0 2.1e-12 47.0 0.0 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEY66024.1 - 5.2e-12 46.0 0.4 2.6e-11 43.7 0.4 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEY66024.1 - 0.25 11.3 8.6 0.62 10.0 5.1 2.8 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily DAO PF01266.24 KEY66025.1 - 3.8e-41 141.9 0.4 4.9e-41 141.5 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KEY66025.1 - 1.2e-11 44.4 0.1 3.2e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_oxidored PF12831.7 KEY66025.1 - 2.8e-08 33.5 1.0 0.0015 18.0 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY66025.1 - 1.5e-06 28.4 0.3 3.6e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY66025.1 - 2.2e-06 27.0 0.8 3.7e-06 26.3 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY66025.1 - 8.3e-06 25.2 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY66025.1 - 2.5e-05 23.7 0.3 5.6e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY66025.1 - 0.00042 19.7 0.1 0.002 17.4 0.1 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY66025.1 - 0.00048 19.3 1.2 0.0078 15.3 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KEY66025.1 - 0.00049 20.6 0.2 0.018 15.6 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY66025.1 - 0.0033 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KEY66025.1 - 0.005 16.7 0.2 0.0083 16.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KEY66025.1 - 0.0052 15.5 0.2 0.041 12.6 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KEY66025.1 - 0.0053 15.9 0.3 0.017 14.2 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEY66025.1 - 0.017 14.4 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEY66025.1 - 0.12 11.9 1.0 0.23 11.0 1.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KEY66025.1 - 0.16 11.2 0.5 0.27 10.5 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KEY66026.1 - 2.2e-15 56.8 0.4 3.4e-14 52.9 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY66026.1 - 0.072 13.3 0.0 0.8 10.0 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain An_peroxidase PF03098.15 KEY66027.1 - 2.3e-122 409.3 0.0 2.9e-122 409.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Acyl_transf_3 PF01757.22 KEY66028.1 - 4.7e-31 108.1 31.7 3.2e-30 105.4 31.7 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 KEY66028.1 - 0.0055 16.7 5.5 0.0055 16.7 5.5 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF418) COesterase PF00135.28 KEY66031.1 - 9.9e-06 24.7 0.1 1.2e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KEY66032.1 - 9.8e-08 32.0 0.9 1.6e-07 31.3 0.9 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY66032.1 - 1.3e-07 32.5 4.3 1.7e-07 32.1 4.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY66032.1 - 2.7e-06 26.8 0.1 4.2e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY66033.1 - 1.1e-06 28.3 0.6 0.0051 16.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEY66033.1 - 1.9e-06 27.4 0.1 0.00094 18.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 KEY66033.1 - 1.7e-05 24.3 1.1 0.013 14.8 0.4 2.2 2 0 0 2 2 2 2 Secretory lipase DLH PF01738.18 KEY66033.1 - 0.038 13.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3528 PF12045.8 KEY66033.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) Abhydrolase_2 PF02230.16 KEY66034.1 - 3.7e-53 180.5 0.0 4.1e-31 108.5 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KEY66034.1 - 1.2e-08 34.5 0.8 0.0021 17.4 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEY66034.1 - 1.2e-05 25.2 0.0 0.035 14.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KEY66034.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KEY66034.1 - 0.0006 20.5 8.0 0.006 17.2 8.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KEY66034.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY66034.1 - 0.0014 18.3 2.3 3 7.4 0.1 3.3 2 2 1 3 3 3 2 alpha/beta hydrolase fold FSH1 PF03959.13 KEY66034.1 - 0.0015 18.2 0.0 0.0079 15.9 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KEY66034.1 - 0.019 14.4 0.4 0.21 11.0 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KEY66034.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2920 PF11144.8 KEY66034.1 - 0.12 11.5 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Cutinase PF01083.22 KEY66034.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase FAD_binding_4 PF01565.23 KEY66035.1 - 3.1e-25 88.5 2.1 5.2e-25 87.8 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66035.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.6 KEY66036.1 - 1.4e-11 44.5 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66036.1 - 2.8e-09 37.5 0.0 7.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66036.1 - 4.5e-09 36.9 0.0 1.3e-06 29.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66036.1 - 6.7e-07 29.2 0.0 4.9e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66036.1 - 1.1e-06 29.3 0.0 0.0037 18.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEY66036.1 - 3.9e-06 26.4 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KEY66036.1 - 0.033 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) His_Phos_1 PF00300.22 KEY66037.1 - 3.8e-36 124.6 1.0 6.1e-34 117.4 1.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_13 PF13166.6 KEY66038.1 - 0.066 11.8 3.9 0.077 11.6 3.9 1.0 1 0 0 1 1 1 0 AAA domain RskA PF10099.9 KEY66038.1 - 0.083 13.2 5.4 0.092 13.0 5.4 1.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LppA PF16708.5 KEY66038.1 - 1.6 8.7 5.2 0.66 9.9 1.8 1.9 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DUF5320 PF17253.2 KEY66038.1 - 1.7 9.8 4.1 0.49 11.5 1.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Osmo_CC PF08946.10 KEY66038.1 - 9.8 6.5 16.7 6.6 7.1 0.3 3.8 3 1 1 4 4 4 0 Osmosensory transporter coiled coil UCH PF00443.29 KEY66039.1 - 1.1e-48 166.0 0.0 1.4e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY66039.1 - 1.3e-13 51.3 1.0 4.1e-13 49.6 1.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KEY66039.1 - 2.3e-12 46.5 0.2 5e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KEY66039.1 - 0.1 12.5 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KEY66039.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain ARPC4 PF05856.12 KEY66040.1 - 4e-78 260.8 3.8 4.9e-78 260.5 3.8 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Methyltransf_23 PF13489.6 KEY66042.1 - 1.1e-18 67.6 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66042.1 - 9.5e-11 42.3 0.0 6.6e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66042.1 - 1.1e-08 35.6 0.0 8.8e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66042.1 - 9.7e-07 29.5 0.0 4.9e-05 24.0 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66042.1 - 0.0001 22.1 0.0 0.0017 18.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEY66042.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KEY66042.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KEY66042.1 - 0.02 14.3 0.0 0.47 9.7 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEY66042.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KEY66042.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CRAL_TRIO PF00650.20 KEY66043.1 - 1.9e-13 50.5 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY66043.1 - 3.7e-06 27.0 0.0 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain SET PF00856.28 KEY66044.1 - 7.1e-15 55.8 0.3 8.8e-14 52.2 0.3 2.5 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KEY66044.1 - 7.8e-08 32.2 7.8 2.3e-07 30.7 7.8 1.8 1 0 0 1 1 1 1 AWS domain DHHC PF01529.20 KEY66045.1 - 6.4e-26 91.0 0.3 6.4e-26 91.0 0.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase ISK_Channel PF02060.15 KEY66045.1 - 0.011 15.5 0.4 0.011 15.5 0.4 1.8 2 0 0 2 2 2 0 Slow voltage-gated potassium channel IMS PF00817.20 KEY66046.1 - 4.5e-40 137.1 0.0 7e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEY66046.1 - 1.8e-15 57.7 0.0 3.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KEY66046.1 - 8.4e-11 41.3 4.1 1.7e-10 40.3 4.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KEY66046.1 - 0.013 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif zf-C2H2 PF00096.26 KEY66046.1 - 0.026 15.0 0.1 0.061 13.8 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY66046.1 - 0.055 14.3 0.1 0.16 12.9 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger IBN_N PF03810.19 KEY66048.1 - 2e-13 50.1 5.6 2.1e-12 46.8 0.1 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KEY66048.1 - 1.3e-08 34.1 0.1 4.6e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 KEY66048.1 - 3.5e-05 23.9 0.5 0.00037 20.6 0.1 2.9 2 0 0 2 2 2 1 Exportin 1-like protein GRIP PF01465.20 KEY66048.1 - 0.0093 15.9 0.1 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 GRIP domain Cnd1 PF12717.7 KEY66048.1 - 0.14 12.2 2.2 0.55 10.2 0.2 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CPL PF08144.11 KEY66048.1 - 0.22 11.9 1.0 12 6.2 0.0 3.7 3 1 0 3 3 3 0 CPL (NUC119) domain Vac14_Fab1_bd PF12755.7 KEY66048.1 - 2.6 8.7 5.7 5.3 7.7 0.1 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ISN1 PF06437.11 KEY66049.1 - 1.1e-175 584.5 0.0 1.3e-175 584.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pkinase PF00069.25 KEY66050.1 - 3e-51 174.3 0.0 4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66050.1 - 5.5e-26 91.4 0.7 3.3e-24 85.6 0.1 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY66050.1 - 0.0037 16.6 0.4 0.019 14.3 0.1 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KEY66050.1 - 0.057 13.0 0.2 12 5.4 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KEY66050.1 - 0.059 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEY66050.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 KEY66051.1 - 2.6e-10 39.6 0.0 3.5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sigma_reg_N PF13800.6 KEY66052.1 - 0.09 13.1 2.6 2.5 8.4 0.8 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal GIDE PF12483.8 KEY66052.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase adh_short PF00106.25 KEY66053.1 - 5.4e-12 45.6 0.0 2.1e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY66053.1 - 0.0039 17.1 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KEY66054.1 - 2.9e-31 108.8 0.0 5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY66055.1 - 1.2e-19 70.4 2.4 2.1e-19 69.6 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KEY66056.1 - 1.9e-80 270.4 0.4 2.4e-80 270.1 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KEY66056.1 - 1.2e-26 93.1 0.1 3.3e-26 91.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Aldo_ket_red PF00248.21 KEY66057.1 - 1.2e-53 182.2 0.0 1.5e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SIS PF01380.22 KEY66058.1 - 1.7e-12 47.3 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 SIS domain PK_C PF02887.16 KEY66058.1 - 0.097 12.9 0.1 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain MFS_1 PF07690.16 KEY66059.1 - 1.5e-32 112.9 36.5 1.5e-32 112.9 36.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66059.1 - 2.1e-10 40.1 7.2 2.1e-10 40.1 7.2 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEY66059.1 - 3.8e-09 35.5 3.0 6.1e-09 34.9 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 KEY66059.1 - 0.003 17.0 2.6 0.017 14.6 2.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_1 PF07690.16 KEY66060.1 - 1.1e-22 80.4 23.0 1.1e-22 80.4 23.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66060.1 - 0.00049 19.1 31.1 0.013 14.4 10.5 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KEY66060.1 - 0.28 9.4 11.4 0.21 9.8 1.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5336 PF17270.2 KEY66060.1 - 0.63 9.6 0.0 0.63 9.6 0.0 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5336) FAD_binding_4 PF01565.23 KEY66061.1 - 3.1e-22 78.8 2.1 7.2e-22 77.6 2.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66061.1 - 7.9e-11 41.9 0.0 1.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 KEY66061.1 - 0.0025 17.6 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase PEP_mutase PF13714.6 KEY66062.1 - 1.7e-71 240.5 3.2 3.5e-71 239.4 3.2 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HpcH_HpaI PF03328.14 KEY66062.1 - 5.9e-26 91.0 0.0 1.2e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Bac_luciferase PF00296.20 KEY66062.1 - 0.0048 16.4 1.2 1.2 8.4 0.4 2.3 2 0 0 2 2 2 2 Luciferase-like monooxygenase Fungal_trans PF04082.18 KEY66062.1 - 0.0085 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ICL PF00463.21 KEY66062.1 - 0.014 13.9 0.3 0.026 13.0 0.3 1.4 1 0 0 1 1 1 0 Isocitrate lyase family Aminotran_1_2 PF00155.21 KEY66063.1 - 2.1e-69 234.5 0.0 2.3e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_3 PF01494.19 KEY66064.1 - 4.5e-42 144.5 0.0 6.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY66064.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2502 PF10697.9 KEY66065.1 - 0.00033 21.0 1.0 0.00045 20.5 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2502) Amidohydro_1 PF01979.20 KEY66066.1 - 2.1e-13 50.3 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY66066.1 - 0.00032 20.3 0.0 0.00066 19.3 0.1 1.5 2 0 0 2 2 2 1 Amidohydrolase family TPP_enzyme_M PF00205.22 KEY66066.1 - 0.08 12.7 0.0 2.3 7.9 0.0 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HTH_19 PF12844.7 KEY66067.1 - 0.18 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3425 PF11905.8 KEY66068.1 - 3.1e-14 53.0 0.1 7.7e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KEY66069.1 - 2.9e-24 85.6 0.0 7e-23 81.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66069.1 - 2.5e-19 69.8 0.0 6.2e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66069.1 - 3.6e-05 23.8 0.4 6.3e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66069.1 - 0.0012 18.3 0.3 0.0074 15.8 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KEY66071.1 - 1.3e-22 80.1 1.2 2.7e-22 79.0 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66071.1 - 1.8e-07 31.1 0.0 4.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short_C2 PF13561.6 KEY66072.1 - 1.1e-59 201.9 4.6 1.3e-59 201.6 4.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66072.1 - 1.2e-44 152.1 2.9 1.6e-44 151.7 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66072.1 - 1.1e-15 58.0 0.8 1.5e-15 57.5 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66072.1 - 0.03 13.8 0.4 0.25 10.8 0.2 1.9 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family PALP PF00291.25 KEY66072.1 - 0.047 13.1 1.4 0.089 12.2 1.0 1.7 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme tRNA-synt_1d PF00750.19 KEY66072.1 - 0.048 12.6 0.1 0.1 11.5 0.1 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (R) S4 PF01479.25 KEY66072.1 - 0.051 13.3 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 S4 domain Ribosomal_S6e PF01092.19 KEY66072.1 - 0.14 12.1 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S6e CBM_1 PF00734.18 KEY66073.1 - 7.2e-12 45.1 5.0 7.2e-12 45.1 5.0 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain MGC-24 PF05283.11 KEY66073.1 - 0.4 11.1 4.3 0.91 10.0 4.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AA_permease_2 PF13520.6 KEY66074.1 - 1.2e-64 218.7 52.8 1.5e-64 218.4 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY66074.1 - 4.3e-29 101.4 48.1 6e-29 101.0 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease NMT1 PF09084.11 KEY66075.1 - 1.6e-78 263.6 0.0 2e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KEY66075.1 - 8.9e-06 25.6 0.1 0.3 10.7 0.0 3.2 3 0 0 3 3 3 3 NMT1-like family Umbravirus_LDM PF04817.12 KEY66076.1 - 0.048 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Glyco_hydro_61 PF03443.14 KEY66077.1 - 1.6e-63 214.4 0.0 1.9e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SurE PF01975.17 KEY66078.1 - 2.6e-13 50.2 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Sugar_tr PF00083.24 KEY66079.1 - 1.3e-120 403.3 17.8 1.6e-120 403.0 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66079.1 - 2.7e-20 72.6 31.9 2.9e-20 72.5 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KEY66080.1 - 5.4e-21 74.8 1.2 9.1e-21 74.0 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66080.1 - 7.4e-08 32.4 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PHO4 PF01384.20 KEY66081.1 - 1.2e-109 366.4 12.4 1.4e-109 366.2 12.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 KEY66081.1 - 0.031 14.6 0.2 0.031 14.6 0.2 3.3 4 2 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family adh_short_C2 PF13561.6 KEY66082.1 - 2.4e-44 151.7 1.7 4.3e-44 150.8 1.7 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66082.1 - 2.2e-43 148.0 2.8 3.4e-43 147.4 2.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 KEY66082.1 - 4.4e-14 52.1 0.0 1.1e-13 50.8 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain KR PF08659.10 KEY66082.1 - 2.3e-07 30.9 1.0 6.7e-07 29.4 1.0 1.8 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KEY66082.1 - 0.00095 19.1 0.2 0.0027 17.6 0.2 1.7 1 0 0 1 1 1 1 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 KEY66082.1 - 0.033 13.5 1.6 0.13 11.6 0.2 2.7 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 KEY66082.1 - 0.15 12.7 1.2 0.47 11.1 1.2 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MbeB_N PF04837.12 KEY66082.1 - 0.25 11.7 1.9 0.29 11.5 0.4 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Cyclase PF04199.13 KEY66083.1 - 2e-15 57.2 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_3 PF00933.21 KEY66084.1 - 3.3e-40 138.4 0.0 4.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY66084.1 - 3.2e-39 135.0 0.0 7.2e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KEY66084.1 - 1.5e-19 69.8 0.1 3.5e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain G-alpha PF00503.20 KEY66085.1 - 1.4e-110 369.8 0.6 1.6e-110 369.6 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEY66085.1 - 2.3e-13 50.0 0.2 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEY66085.1 - 0.0001 21.7 0.9 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KEY66085.1 - 0.0081 16.4 0.1 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KEY66085.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KEY66085.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spermine_synth PF01564.17 KEY66087.1 - 1.2e-67 226.9 0.0 9.8e-67 224.0 0.0 2.3 2 1 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KEY66087.1 - 3.8e-26 90.7 0.2 6.6e-26 90.0 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KEY66087.1 - 0.014 16.1 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 KEY66088.1 - 2.8e-57 194.0 0.0 3.2e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PhyH PF05721.13 KEY66090.1 - 2.4e-60 204.4 0.0 2.9e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KEY66090.1 - 0.082 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2373 PF10180.9 KEY66091.1 - 8.9e-25 86.3 0.6 1.6e-24 85.5 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) SPX PF03105.19 KEY66091.1 - 1.7 8.5 28.7 2.3 8.0 14.3 2.2 2 0 0 2 2 2 0 SPX domain Proteasome PF00227.26 KEY66092.1 - 1.8e-48 164.5 0.0 2.5e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEY66092.1 - 6e-11 41.8 0.2 6e-11 41.8 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TMEM234 PF10639.9 KEY66094.1 - 1.1e-27 96.4 0.0 1.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF1211 PF06736.11 KEY66094.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Con-6 PF10346.9 KEY66095.1 - 2.3e-32 110.7 7.2 1.9e-17 62.9 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 ATP-synt_DE PF00401.20 KEY66095.1 - 0.016 15.5 0.5 0.5 10.7 0.5 2.2 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Glyco_transf_8C PF08437.10 KEY66095.1 - 0.055 13.6 0.9 4.6 7.4 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal SpoIIIAH PF12685.7 KEY66095.1 - 0.068 13.0 5.5 0.38 10.5 5.5 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein WD40 PF00400.32 KEY66096.1 - 5.5e-39 131.5 15.4 5.5e-10 39.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY66096.1 - 5.3e-14 52.3 0.8 0.022 15.0 0.0 4.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY66096.1 - 1.3e-10 40.8 0.4 0.22 10.5 0.0 4.6 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEY66096.1 - 2.9e-06 26.2 3.6 0.092 11.4 0.1 4.8 4 1 1 5 5 5 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEY66096.1 - 3.5e-05 22.9 3.9 5.2e-05 22.3 0.1 2.9 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KEY66096.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region HPS3_N PF14761.6 KEY66096.1 - 0.0015 18.1 0.0 0.024 14.2 0.0 2.4 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 Yeast-kill-tox PF09207.11 KEY66096.1 - 0.0026 18.4 0.7 0.096 13.3 0.4 2.7 2 0 0 2 2 2 1 Yeast killer toxin Frtz PF11768.8 KEY66096.1 - 0.0079 14.6 0.0 0.065 11.5 0.0 2.2 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KEY66096.1 - 0.043 13.5 1.5 16 5.1 0.1 3.2 1 1 1 2 2 2 0 TUP1-like enhancer of split FHA PF00498.26 KEY66097.1 - 3.5e-11 43.3 0.0 8.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain DNA_pol_phi PF04931.13 KEY66097.1 - 0.053 11.6 20.4 0.096 10.8 20.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KEY66097.1 - 0.08 13.0 13.2 0.28 11.2 13.2 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KEY66097.1 - 0.38 10.0 16.7 0.8 9.0 16.7 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KEY66097.1 - 1.7 6.7 18.0 2.5 6.2 18.0 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 KEY66097.1 - 2.7 8.1 7.6 6.2 6.9 7.6 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IFRD PF05004.13 KEY66098.1 - 1.4e-51 175.4 1.2 1.9e-51 175.0 1.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_N PF03224.14 KEY66098.1 - 0.13 11.6 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Abhydrolase_2 PF02230.16 KEY66099.1 - 0.19 11.5 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aminotran_5 PF00266.19 KEY66100.1 - 9.7e-93 311.1 0.0 1.2e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEY66100.1 - 2.3e-08 33.7 0.0 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEY66100.1 - 8.1e-07 28.7 0.7 3.8e-06 26.5 0.3 2.1 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEY66100.1 - 0.0006 18.4 0.0 0.00098 17.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KEY66100.1 - 0.0012 17.7 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 KEY66101.1 - 1.9e-67 227.4 6.4 2.3e-67 227.1 6.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KEY66101.1 - 1.8e-15 56.2 0.1 3.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY66101.1 - 3e-12 46.2 0.1 5.5e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY66101.1 - 5.3e-10 38.8 0.2 4e-09 36.0 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain BAR_3 PF16746.5 KEY66101.1 - 0.02 14.6 3.0 0.034 13.8 3.0 1.4 1 0 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 KEY66101.1 - 0.069 12.4 3.8 0.47 9.6 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Arfaptin PF06456.13 KEY66101.1 - 0.75 9.3 8.7 5.6 6.5 8.7 2.0 1 1 0 1 1 1 0 Arfaptin-like domain F-box PF00646.33 KEY66102.1 - 0.0067 16.3 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KEY66102.1 - 0.02 14.8 0.0 0.31 11.0 0.0 2.7 2 0 0 2 2 2 0 F-box-like SPX PF03105.19 KEY66103.1 - 0.48 10.3 2.2 0.57 10.0 2.2 1.1 1 0 0 1 1 1 0 SPX domain YdaS_antitoxin PF15943.5 KEY66105.1 - 0.018 14.9 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_8 PF02954.19 KEY66105.1 - 0.02 14.7 1.3 0.21 11.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 KEY66105.1 - 0.13 12.6 1.1 0.35 11.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KEY66105.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.13 KEY66105.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3716 PF12511.8 KEY66110.1 - 0.0032 17.5 3.5 0.008 16.2 3.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) 7tm_2 PF00002.24 KEY66111.1 - 1.1e-05 24.9 13.8 2.4e-05 23.7 13.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Htr2 PF17909.1 KEY66111.1 - 2.5 8.4 5.5 0.98 9.7 0.2 2.9 3 0 0 3 3 3 0 Htr2 transmembrane domain Cellulase PF00150.18 KEY66112.1 - 4e-35 121.6 0.1 4.7e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Med3 PF11593.8 KEY66112.1 - 1.9 7.6 4.6 2.7 7.1 4.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CRT10 PF08728.10 KEY66113.1 - 6.3e-15 54.4 0.0 8.3e-11 40.8 0.0 2.2 2 0 0 2 2 2 2 CRT10 Miff PF05644.11 KEY66113.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Nuclease_act PF08133.11 KEY66113.1 - 0.1 12.8 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Anticodon nuclease activator family Ammonium_transp PF00909.21 KEY66114.1 - 8e-113 377.1 31.7 9.2e-113 376.9 31.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Epiglycanin_C PF14654.6 KEY66114.1 - 0.46 10.6 4.1 3.7 7.6 0.0 3.2 3 1 1 4 4 4 0 Mucin, catalytic, TM and cytoplasmic tail region His_Phos_2 PF00328.22 KEY66115.1 - 3.4e-48 164.9 0.0 4e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TauD PF02668.16 KEY66117.1 - 4.1e-24 85.8 0.0 7.7e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEY66117.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.18 KEY66118.1 - 0.0044 17.1 3.8 0.0085 16.2 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 KEY66119.1 - 5 7.1 22.5 0.19 11.7 16.0 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein B277 PF17623.2 KEY66119.1 - 7.8 5.5 4.7 10 5.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function SSP160 PF06933.11 KEY66119.1 - 8.2 4.5 14.1 13 3.8 14.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 KEY66120.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KEY66120.1 - 0.024 14.5 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KEY66120.1 - 0.036 13.4 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase RRM_1 PF00076.22 KEY66122.1 - 1.4e-14 53.7 0.1 2.4e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY66122.1 - 2.8e-05 23.7 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY66122.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Gemin6 PF06372.12 KEY66122.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein HhH-GPD PF00730.25 KEY66123.1 - 0.00054 20.4 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SURF4 PF02077.15 KEY66124.1 - 1.2e-91 307.0 7.2 1.4e-91 306.8 7.2 1.1 1 0 0 1 1 1 1 SURF4 family HeLo PF14479.6 KEY66125.1 - 1.1e-38 133.1 0.0 7.1e-29 101.1 0.0 3.2 3 0 0 3 3 3 3 Prion-inhibition and propagation DSPn PF14671.6 KEY66126.1 - 2.4e-41 141.5 0.0 5.3e-39 133.9 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KEY66126.1 - 4.1e-17 62.2 0.0 8.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEY66126.1 - 2.8e-06 27.1 0.2 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEY66126.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Pcc1 PF09341.10 KEY66127.1 - 8.2e-31 106.0 0.9 1e-30 105.7 0.9 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HLH PF00010.26 KEY66128.1 - 9.4e-11 41.5 0.3 9.4e-11 41.5 0.3 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KEY66128.1 - 0.063 13.4 1.2 0.24 11.5 1.2 2.0 1 0 0 1 1 1 0 bZIP transcription factor DUF4358 PF14270.6 KEY66128.1 - 0.38 11.1 1.5 1.7 9.0 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) Cnn_1N PF07989.11 KEY66128.1 - 0.4 10.9 5.6 0.088 13.0 0.9 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KEY66128.1 - 4.1 7.3 9.3 0.63 9.8 1.1 2.7 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KEY66128.1 - 9.3 6.6 7.0 1.5 9.1 2.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Kelch_3 PF13415.6 KEY66129.1 - 8.2e-06 26.0 9.0 0.00022 21.4 0.2 5.7 7 0 0 7 7 7 1 Galactose oxidase, central domain Rax2 PF12768.7 KEY66129.1 - 0.00043 19.8 0.1 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 KEY66129.1 - 0.012 15.5 0.4 0.031 14.2 0.4 1.7 1 0 0 1 1 1 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 KEY66129.1 - 0.024 14.9 3.5 0.055 13.7 3.5 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 KEY66129.1 - 0.054 13.9 2.0 0.19 12.2 2.0 2.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gram_pos_anchor PF00746.21 KEY66129.1 - 0.48 10.4 3.8 1.2 9.1 3.8 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TAP_C PF03943.13 KEY66130.1 - 1.1e-18 66.6 1.1 2.2e-18 65.6 0.6 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 KEY66130.1 - 3e-06 27.5 0.6 0.00068 20.0 0.1 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KEY66130.1 - 1.2e-05 25.8 0.0 5.8e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 KEY66130.1 - 0.00079 19.2 0.0 0.0053 16.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KEY66130.1 - 0.025 14.3 0.1 0.088 12.6 0.1 1.9 1 1 1 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 KEY66130.1 - 0.29 11.3 2.2 2.7 8.3 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Helicase_C PF00271.31 KEY66131.1 - 8.1e-22 77.7 0.1 2.1e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY66131.1 - 5.6e-21 75.3 0.0 1.1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEY66131.1 - 2.1e-16 60.2 0.0 4.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KEY66131.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KEY66131.1 - 0.003 17.8 0.0 0.016 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Carbpep_Y_N PF05388.11 KEY66131.1 - 0.12 13.0 0.0 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide ATP-grasp_2 PF08442.10 KEY66131.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF1772 PF08592.11 KEY66132.1 - 2.1e-06 28.1 1.9 3e-06 27.6 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ABC2_membrane_2 PF12679.7 KEY66132.1 - 0.0031 16.8 0.1 0.0042 16.4 0.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein Ank_2 PF12796.7 KEY66133.1 - 9.8e-45 151.1 6.0 4.1e-14 52.9 0.0 10.0 7 2 3 10 10 10 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY66133.1 - 1.6e-34 117.8 1.7 6e-05 23.5 0.0 11.6 9 3 3 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66133.1 - 1.1e-33 111.4 8.7 0.0018 18.6 0.0 14.0 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.6 KEY66133.1 - 2.1e-30 104.4 0.8 0.00068 19.9 0.0 10.3 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KEY66133.1 - 1e-26 92.2 13.8 0.0013 19.0 0.0 12.3 13 0 0 13 13 13 5 Ankyrin repeat LPD22 PF18834.1 KEY66133.1 - 0.1 12.8 0.4 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 ABC_tran_Xtn PF12848.7 KEY66133.1 - 4.9 7.2 9.5 0.55 10.3 1.3 3.0 2 0 0 2 2 2 0 ABC transporter DEAD PF00270.29 KEY66134.1 - 2.4e-22 79.5 0.0 5.3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY66134.1 - 2.1e-17 63.5 0.0 1.4e-13 51.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KEY66134.1 - 3.4e-16 59.7 4.1 1.1e-15 58.1 4.1 2.0 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KEY66134.1 - 2.2e-14 53.2 0.0 4.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KEY66134.1 - 3e-09 37.1 0.0 8.1e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KEY66134.1 - 0.0004 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain SecA_DEAD PF07517.14 KEY66134.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Syntaxin-18_N PF10496.9 KEY66134.1 - 1.1 9.6 3.5 14 6.0 0.8 3.8 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DEADboxA PF12343.8 KEY66134.1 - 2.9 8.5 20.6 19 5.9 15.7 2.8 2 0 0 2 2 2 0 Cold shock protein DEAD box A KAR9 PF08580.10 KEY66135.1 - 2.5e-178 594.8 8.8 2.5e-178 594.8 8.8 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DUF4795 PF16043.5 KEY66135.1 - 5.9 6.4 7.1 15 5.1 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) CH PF00307.31 KEY66136.1 - 0.032 14.4 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain HSP20 PF00011.21 KEY66137.1 - 8e-11 42.0 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEY66137.1 - 0.0067 16.0 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Abhydrolase_3 PF07859.13 KEY66138.1 - 2.6e-41 141.8 0.0 5.9e-41 140.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY66138.1 - 0.048 12.5 0.1 0.097 11.5 0.1 1.5 1 1 0 1 1 1 0 Carboxylesterase family COX17 PF05051.13 KEY66139.1 - 1.7e-20 73.1 6.6 2e-20 72.8 6.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) MnmE_helical PF12631.7 KEY66140.1 - 0.0023 18.1 1.0 0.0026 18.0 1.0 1.1 1 0 0 1 1 1 1 MnmE helical domain SOAR PF16533.5 KEY66140.1 - 0.057 13.4 7.4 0.18 11.8 3.2 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region Imm51 PF15595.6 KEY66140.1 - 0.058 13.3 1.0 1.7 8.6 0.1 2.1 1 1 1 2 2 2 0 Immunity protein 51 Lyase_catalyt PF09093.11 KEY66140.1 - 0.18 10.9 1.1 0.2 10.8 1.1 1.0 1 0 0 1 1 1 0 Lyase, catalytic DUF737 PF05300.11 KEY66140.1 - 0.77 10.1 9.0 0.97 9.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Cpn60_TCP1 PF00118.24 KEY66141.1 - 2e-147 491.8 15.5 2.3e-147 491.6 15.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KEY66142.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY66142.1 - 2.3e-07 30.5 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEY66142.1 - 8.2e-05 22.6 0.1 0.00062 19.8 0.0 2.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY66142.1 - 0.00015 22.1 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KEY66142.1 - 0.00044 20.4 0.0 0.0016 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEY66142.1 - 0.00073 20.0 0.1 0.014 15.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KEY66142.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KEY66142.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KEY66142.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEY66142.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEY66142.1 - 0.04 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KEY66142.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KEY66142.1 - 0.059 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEY66142.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY66142.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEY66142.1 - 0.13 11.9 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEY66142.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytochrom_C1 PF02167.15 KEY66145.1 - 8.2e-92 306.9 0.0 1e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KEY66145.1 - 0.0063 16.8 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KEY66145.1 - 0.087 14.0 0.0 0.33 12.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c LRR_4 PF12799.7 KEY66146.1 - 1.1e-09 38.4 6.3 0.057 13.9 0.0 5.1 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEY66146.1 - 2.6e-08 33.3 12.6 0.0053 16.7 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 KEY66146.1 - 2.8e-05 23.8 13.5 0.25 11.1 0.1 4.7 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KEY66146.1 - 2.8e-05 24.0 0.2 10 7.1 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat Sigma70_ner PF04546.13 KEY66146.1 - 5.7 6.8 17.1 9.9 6.0 17.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Radial_spoke PF04712.12 KEY66146.1 - 6.3 5.6 14.9 9.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein Proteasome PF00227.26 KEY66148.1 - 1.9e-45 154.7 0.2 4.3e-32 111.1 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KEY66148.1 - 6.7e-11 41.7 0.7 9.2e-11 41.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_pol_phi PF04931.13 KEY66149.1 - 5.6e-186 620.0 39.0 3e-185 617.6 39.0 1.9 1 1 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KEY66149.1 - 0.00068 19.2 30.9 0.002 17.7 30.9 1.7 1 0 0 1 1 1 1 SDA1 DUF1676 PF07898.13 KEY66149.1 - 0.28 11.2 4.3 0.7 9.9 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Rhodanese PF00581.20 KEY66150.1 - 2.8e-12 47.1 0.0 5.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Nup_retrotrp_bd PF10599.9 KEY66150.1 - 1.2 9.8 9.2 1.3 9.7 0.0 2.9 3 0 0 3 3 3 0 Retro-transposon transporting motif CwfJ_C_1 PF04677.15 KEY66151.1 - 1.7e-22 79.5 0.0 5e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KEY66151.1 - 4.4e-15 56.4 0.1 8.1e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF3313 PF11769.8 KEY66151.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DRIM PF07539.12 KEY66152.1 - 2.7e-190 633.8 3.2 1.1e-189 631.8 0.0 3.2 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 KEY66152.1 - 1e-05 25.4 1.9 0.74 10.2 0.0 6.8 6 1 1 7 7 7 1 HEAT repeat DUF3385 PF11865.8 KEY66152.1 - 0.027 14.4 0.1 9 6.2 0.0 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) DUF2828 PF11443.8 KEY66152.1 - 0.038 12.1 2.3 0.072 11.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Arm PF00514.23 KEY66152.1 - 0.86 9.7 5.0 13 6.0 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FliS PF02561.14 KEY66152.1 - 0.86 9.9 3.5 1.1 9.6 0.2 3.0 3 0 0 3 3 3 0 Flagellar protein FliS Ribosomal_60s PF00428.19 KEY66152.1 - 1.3 9.7 11.0 0.026 15.1 3.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-DNL PF05180.12 KEY66153.1 - 4.6e-28 97.0 0.5 6.2e-28 96.5 0.5 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KEY66153.1 - 0.14 11.9 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger Zn_Tnp_IS1595 PF12760.7 KEY66153.1 - 8.7 6.4 6.2 8.9 6.4 1.1 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain CAP PF00188.26 KEY66154.1 - 3.3e-08 34.4 0.1 3.4e-08 34.4 0.1 1.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF5 PF04855.12 KEY66155.1 - 2.3e-93 312.4 0.0 2.9e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KEY66155.1 - 5.8e-05 22.6 0.6 5.8e-05 22.6 0.6 2.1 2 0 0 2 2 2 1 GATA zinc finger Glyco_hydro_7 PF00840.20 KEY66156.1 - 4.5e-192 638.6 9.3 5.1e-192 638.4 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ACC_epsilon PF13822.6 KEY66156.1 - 0.33 11.7 1.0 0.69 10.6 1.0 1.5 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit CVNH PF08881.10 KEY66157.1 - 0.034 14.8 0.0 0.052 14.2 0.0 1.2 1 0 0 1 1 1 0 CVNH domain Fungal_trans PF04082.18 KEY66158.1 - 1.8e-15 56.7 1.0 1.8e-15 56.7 1.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66158.1 - 4.5e-07 29.9 9.2 4.5e-07 29.9 9.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.9 KEY66158.1 - 7.9 4.6 50.3 12 4.0 50.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.18 KEY66159.1 - 1.5e-14 53.7 0.0 2.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66159.1 - 0.0078 16.3 5.7 0.0078 16.3 5.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_9 PF13371.6 KEY66160.1 - 0.0008 19.5 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Sod_Cu PF00080.20 KEY66161.1 - 1.7e-13 50.9 0.0 2.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) A_amylase_inhib PF01356.19 KEY66161.1 - 1.2 9.2 3.5 0.67 10.0 0.2 2.2 3 0 0 3 3 3 0 Alpha amylase inhibitor Alpha_GJ PF03229.13 KEY66161.1 - 2.6 8.6 15.9 0.22 12.1 10.3 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J AA_permease_2 PF13520.6 KEY66162.1 - 0.0037 16.2 0.2 0.0042 16.0 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease MHYT PF03707.16 KEY66162.1 - 0.041 14.0 2.1 0.16 12.2 0.4 2.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF4044 PF13253.6 KEY66162.1 - 0.2 11.2 3.3 0.35 10.4 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) TMEMspv1-c74-12 PF11044.8 KEY66162.1 - 4.6 7.3 5.2 1 9.4 0.1 2.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein adh_short_C2 PF13561.6 KEY66163.1 - 9.9e-59 198.7 0.0 1.2e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66163.1 - 9e-46 155.8 0.0 1.2e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66163.1 - 3.3e-12 46.7 0.0 4.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY66163.1 - 0.0025 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KEY66163.1 - 0.057 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF4291 PF14124.6 KEY66164.1 - 2e-65 220.1 0.0 2.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) VPS9 PF02204.18 KEY66165.1 - 2.5e-30 104.8 0.1 4.7e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KEY66165.1 - 3.6e-16 59.2 0.1 7.6e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KEY66165.1 - 0.00055 19.6 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 CUE domain TRP PF06011.12 KEY66166.1 - 3.8e-144 480.6 19.4 4.6e-144 480.3 19.4 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEY66166.1 - 4.2e-40 137.3 0.3 7e-40 136.6 0.3 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 KEY66166.1 - 0.78 10.0 2.5 11 6.2 0.3 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Fungal_trans PF04082.18 KEY66167.1 - 3.9e-07 29.4 0.5 6.9e-07 28.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66167.1 - 4.1e-07 30.0 8.6 8.4e-07 29.0 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KEY66168.1 - 3e-20 72.2 7.5 6.4e-05 23.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY66168.1 - 1.4e-07 31.7 0.2 0.018 15.3 0.0 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KEY66168.1 - 0.075 13.0 0.2 66 3.7 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Glyco_transf_15 PF01793.16 KEY66169.1 - 2.1e-113 378.9 8.6 2.5e-113 378.6 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 KEY66170.1 - 7.7e-42 144.0 0.2 1.5e-41 143.0 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KEY66170.1 - 7.4e-25 88.1 0.0 1.6e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KEY66170.1 - 2.1e-12 46.2 0.4 3.2e-12 45.6 0.4 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Abhydrolase_2 PF02230.16 KEY66171.1 - 1.4e-10 41.4 0.0 2.7e-10 40.4 0.0 1.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KEY66171.1 - 2.2e-05 25.2 2.0 2.7e-05 24.9 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family YjeF_N PF03853.15 KEY66171.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus LCCL PF03815.19 KEY66172.1 - 1.7e-20 72.9 0.2 3.1e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 LCCL domain Peptidase_U4 PF03419.13 KEY66172.1 - 3.4 6.9 6.9 6 6.1 6.9 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TGT PF01702.18 KEY66173.1 - 1.7e-62 211.6 0.0 2.2e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.20 KEY66174.1 - 3.7e-64 217.2 0.2 7.4e-60 203.0 0.0 2.8 2 1 0 2 2 2 2 Alkaline phosphatase Sulfatase PF00884.23 KEY66174.1 - 1.8e-05 24.3 0.1 4.3e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEY66174.1 - 2.7e-05 23.9 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KEY66174.1 - 0.0081 14.8 0.1 0.034 12.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KEY66174.1 - 0.028 13.5 0.2 0.043 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CutC PF03932.14 KEY66175.1 - 5.5e-31 107.6 0.0 1.2e-30 106.5 0.0 1.5 1 1 0 1 1 1 1 CutC family NAP PF00956.18 KEY66176.1 - 1.4e-26 93.3 13.0 7.2e-26 90.9 5.2 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 KEY66176.1 - 2.2 8.0 18.3 5.1 6.8 18.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tub_N PF16322.5 KEY66176.1 - 6 7.2 9.6 0.15 12.5 1.9 1.9 2 0 0 2 2 2 0 Tubby N-terminal PSII_BNR PF14870.6 KEY66177.1 - 6.3e-10 38.8 3.6 1.7e-06 27.5 0.1 3.7 2 2 1 3 3 3 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 KEY66177.1 - 2.2e-07 30.0 0.1 0.00028 19.8 0.0 2.5 2 2 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 KEY66177.1 - 2.9e-07 29.5 26.5 0.12 12.5 0.5 6.4 6 0 0 6 6 6 5 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KEY66177.1 - 0.00015 21.6 0.1 7.9 6.5 0.0 5.2 6 0 0 6 6 6 1 Chitobiase/beta-hexosaminidase C-terminal domain BNR_2 PF13088.6 KEY66177.1 - 0.0018 17.6 1.5 6.1 6.1 0.0 4.0 3 1 1 4 4 4 2 BNR repeat-like domain Questin_oxidase PF14027.6 KEY66179.1 - 4.8e-92 309.1 0.6 5.7e-92 308.9 0.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like WD40 PF00400.32 KEY66180.1 - 4.5e-39 131.7 29.5 5.6e-08 33.3 0.0 14.0 15 0 0 15 15 15 7 WD domain, G-beta repeat Utp12 PF04003.12 KEY66180.1 - 4.1e-24 84.9 0.0 7.6e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KEY66180.1 - 6.2e-21 74.5 0.0 0.0028 17.9 0.0 9.9 4 2 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY66180.1 - 1.1e-07 31.1 0.7 2.3 7.1 0.0 6.4 5 2 2 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEY66180.1 - 2.6e-07 30.7 2.4 0.046 13.6 0.1 5.6 6 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEY66180.1 - 0.00059 19.3 0.0 0.93 8.8 0.0 4.2 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 KEY66180.1 - 0.00082 18.1 5.6 0.91 8.1 0.0 4.2 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KEY66180.1 - 0.022 14.1 0.1 7.1 5.9 0.0 3.2 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KEY66180.1 - 0.13 12.8 2.6 59 4.3 0.0 5.3 5 0 0 5 5 5 0 PQQ-like domain Septin PF00735.18 KEY66181.1 - 8.6e-109 363.2 0.2 1.4e-108 362.5 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KEY66181.1 - 1.9e-07 31.1 0.0 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY66181.1 - 3.8e-06 26.9 1.7 2e-05 24.6 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KEY66181.1 - 7.7e-06 25.6 4.3 9.2e-05 22.1 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KEY66181.1 - 0.0012 19.1 0.1 0.0044 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 KEY66181.1 - 0.0035 17.6 0.1 0.0076 16.5 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KEY66181.1 - 0.0039 16.7 0.1 0.0076 15.7 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 KEY66181.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KEY66181.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) KAP_NTPase PF07693.14 KEY66181.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KEY66181.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEY66181.1 - 0.018 14.6 0.2 0.064 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KEY66181.1 - 0.019 14.6 0.5 0.06 12.9 0.5 1.9 2 1 0 2 2 1 0 Ras family ABC_tran PF00005.27 KEY66181.1 - 0.02 15.4 0.3 0.086 13.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Casc1_N PF15927.5 KEY66181.1 - 0.023 14.4 10.5 0.062 13.0 10.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_16 PF13191.6 KEY66181.1 - 0.033 14.6 0.9 0.064 13.6 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEY66181.1 - 0.043 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KEY66181.1 - 0.052 12.6 0.3 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 KEY66181.1 - 0.055 14.1 0.8 0.055 14.1 0.8 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain Dynamin_N PF00350.23 KEY66181.1 - 0.056 13.5 6.9 2.9 7.9 0.1 3.3 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KEY66181.1 - 0.09 12.5 1.4 13 5.5 0.1 3.0 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4808 PF16066.5 KEY66181.1 - 0.13 12.8 0.1 0.51 10.9 0.1 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4808) RNA_helicase PF00910.22 KEY66181.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 KEY66181.1 - 0.13 12.0 0.4 5 6.9 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Val_tRNA-synt_C PF10458.9 KEY66181.1 - 0.19 12.0 4.2 0.14 12.5 0.8 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PRK PF00485.18 KEY66181.1 - 0.3 10.8 2.1 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cep57_CLD_2 PF14197.6 KEY66181.1 - 0.76 9.9 5.6 13 6.0 3.6 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Ribosomal_L6e PF01159.19 KEY66181.1 - 1.3 9.6 6.2 7.6 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e APG6_N PF17675.1 KEY66181.1 - 4 8.0 12.8 0.77 10.3 8.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region BCDHK_Adom3 PF10436.9 KEY66182.1 - 1.1e-43 148.9 0.2 3e-43 147.5 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEY66182.1 - 8.1e-08 32.8 0.0 2.8e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEY66182.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 KEY66183.1 - 1.6e-83 279.7 0.0 5.7e-82 274.6 0.0 2.6 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KEY66183.1 - 1.1e-77 260.4 0.6 8.8e-74 247.7 1.3 3.9 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KEY66183.1 - 4.2e-47 160.8 0.8 8.7e-47 159.8 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY66183.1 - 1.7e-20 73.9 0.1 2.1e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KEY66183.1 - 4e-10 39.8 0.0 1.3e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 MATH domain YukD PF08817.10 KEY66183.1 - 3.8e-06 27.5 0.2 0.5 11.1 0.0 3.6 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD SLBB PF10531.9 KEY66183.1 - 0.014 15.3 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 SLBB domain Rad60-SLD PF11976.8 KEY66183.1 - 0.019 14.8 0.2 16 5.4 0.0 3.8 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like Malt_amylase_C PF16657.5 KEY66183.1 - 0.13 12.4 0.1 31 4.8 0.0 2.7 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Asparaginase PF00710.20 KEY66184.1 - 2.3e-59 200.1 0.0 3.6e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEY66184.1 - 1.6e-26 92.7 0.0 3.3e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KEY66184.1 - 1.8e-12 47.7 0.0 1e-08 35.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY66184.1 - 2.7e-10 40.6 0.1 2.9e-07 30.9 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66184.1 - 1e-09 37.8 0.0 0.0013 19.0 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KEY66184.1 - 1.8e-07 31.3 0.0 0.0048 17.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KEY66184.1 - 1.6e-05 25.1 0.1 0.034 14.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KEY66185.1 - 1.2e-65 221.5 0.0 1.4e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66185.1 - 6.5e-30 104.3 0.0 8.7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY66185.1 - 0.0004 19.8 0.0 0.00097 18.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY66185.1 - 0.00064 18.8 0.0 0.00098 18.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEY66185.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Fibrillin_U_N PF18193.1 KEY66185.1 - 0.032 14.3 0.5 0.068 13.3 0.5 1.4 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain AMPKBI PF04739.15 KEY66187.1 - 6.6e-26 90.4 2.6 6.6e-26 90.4 2.6 2.7 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KEY66187.1 - 1.4e-25 89.3 0.0 2.5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Peptidase_M22 PF00814.25 KEY66188.1 - 5.8e-86 288.6 0.1 7.1e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KEY66188.1 - 0.031 13.9 0.0 0.82 9.3 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus EPL1 PF10513.9 KEY66189.1 - 4.4e-17 62.9 0.4 4.4e-17 62.9 0.4 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 KEY66190.1 - 1.4e-26 90.0 13.2 2.8e-07 29.6 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEY66190.1 - 9.6e-23 80.4 13.3 3.8e-14 52.9 1.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KEY66190.1 - 3.3e-20 70.2 6.6 5.4e-05 22.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEY66190.1 - 4.4e-18 63.9 10.9 2e-06 27.0 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KEY66190.1 - 1.7e-12 47.0 12.9 0.00016 21.5 0.5 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KEY66190.1 - 1.6e-06 28.4 0.1 0.0018 18.6 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KEY66190.1 - 8.3e-06 25.7 8.1 0.0028 17.6 0.5 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KEY66190.1 - 0.036 14.3 0.8 0.14 12.4 0.7 2.1 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 KEY66190.1 - 0.094 13.1 0.2 5.4 7.4 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain DUF2199 PF09965.9 KEY66191.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Ribosomal_S9 PF00380.19 KEY66192.1 - 3.8e-39 133.9 0.6 5.9e-39 133.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 KEY66193.1 - 4e-43 145.8 0.0 7.8e-43 144.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KEY66193.1 - 3e-15 56.2 0.0 8.7e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEY66193.1 - 2e-10 40.9 0.1 1.3e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY66193.1 - 1.2e-09 38.1 0.6 4.3e-09 36.3 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY66193.1 - 2.7e-05 24.3 0.0 8.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY66193.1 - 0.006 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 KEY66194.1 - 1.9e-22 79.7 0.0 3.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 KEY66195.1 - 7.4e-55 185.4 25.1 1.4e-54 184.5 25.1 1.5 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 ABC1 PF03109.16 KEY66196.1 - 1.2e-31 109.4 0.0 2.4e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KEY66196.1 - 0.051 12.9 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Es2 PF09751.9 KEY66197.1 - 2.9e-119 399.6 7.7 3.7e-119 399.3 7.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PPP5 PF08321.12 KEY66198.1 - 2.7e-33 114.1 0.9 5.5e-33 113.1 0.3 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KEY66198.1 - 1.9e-32 113.5 0.3 3.6e-32 112.5 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KEY66198.1 - 4.3e-18 64.3 0.2 0.00012 21.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY66198.1 - 4.2e-13 48.3 0.1 0.0091 16.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY66198.1 - 8.1e-12 44.6 1.1 9.2e-05 22.1 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KEY66198.1 - 1.5e-06 28.0 1.1 0.033 14.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY66198.1 - 1.2e-05 25.3 1.0 0.16 12.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEY66198.1 - 0.00024 21.2 0.0 0.011 15.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY66198.1 - 0.0052 17.5 0.0 4.5 8.4 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY66198.1 - 0.0089 16.3 0.0 1.6 9.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY66198.1 - 0.0098 16.5 0.2 0.29 11.8 0.2 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY66198.1 - 0.042 14.4 0.0 4.1 8.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Flu_M1 PF00598.19 KEY66198.1 - 0.047 13.2 0.0 5.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Influenza Matrix protein (M1) SbsC_C PF18058.1 KEY66198.1 - 0.067 13.4 1.0 19 5.5 0.0 2.5 1 1 0 2 2 2 0 SbsC C-terminal domain Spt4 PF06093.13 KEY66200.1 - 1e-31 108.8 0.2 1.2e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger BH3 PF15285.6 KEY66200.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Kin17_mid PF10357.9 KEY66201.1 - 1.5e-51 173.5 1.3 1.5e-51 173.5 1.3 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KEY66201.1 - 6.2e-05 23.2 2.6 0.00013 22.2 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY66201.1 - 8.4e-05 22.8 4.0 0.00017 21.8 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KEY66201.1 - 0.0021 18.3 0.4 0.0021 18.3 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Ndc1_Nup PF09531.10 KEY66201.1 - 1.5 7.4 9.1 1.8 7.1 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 KEY66202.1 - 3.9e-68 230.5 10.8 4.7e-68 230.3 10.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 KEY66202.1 - 0.24 11.5 2.2 1.8 8.7 0.4 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain HTH_psq PF05225.16 KEY66205.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Arrestin_C PF02752.22 KEY66206.1 - 8.8e-12 45.6 0.0 2.2e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KEY66206.1 - 4.4e-09 36.6 0.0 8.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KEY66206.1 - 0.0018 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Auts2 PF15336.6 KEY66206.1 - 0.059 13.5 1.8 0.15 12.2 1.8 1.6 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein CTD PF12815.7 KEY66206.1 - 0.77 10.4 4.6 12 6.5 1.3 2.8 2 1 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 PH PF00169.29 KEY66207.1 - 0.0025 18.3 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 KEY66207.1 - 0.0081 16.1 0.3 0.0081 16.1 0.3 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain eRF1_3 PF03465.15 KEY66207.1 - 0.14 12.6 0.2 0.5 10.9 0.0 2.0 3 0 0 3 3 3 0 eRF1 domain 3 MFS_1 PF07690.16 KEY66208.1 - 1.7e-37 129.2 28.3 1.1e-27 96.9 7.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66208.1 - 1.2e-13 50.8 1.0 1.2e-13 50.8 1.0 3.3 3 1 0 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KEY66208.1 - 0.00012 20.6 2.5 0.00021 19.9 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFO_IDH_MocA PF01408.22 KEY66209.1 - 1.4e-21 77.5 0.1 2.2e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEY66209.1 - 0.0085 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KEY66209.1 - 0.13 12.9 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HET PF06985.11 KEY66210.1 - 1.5e-28 100.0 0.8 2.5e-23 83.1 0.4 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 KEY66210.1 - 5.3e-12 46.0 0.2 5.1e-10 39.7 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY66210.1 - 1e-10 42.0 0.0 2.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY66210.1 - 3.6e-10 39.9 0.8 1.5e-09 37.9 0.5 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66210.1 - 2.1e-05 24.5 0.0 0.061 13.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KEY66210.1 - 7.6e-05 23.0 0.5 0.037 14.5 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeat GST_N_4 PF17172.4 KEY66212.1 - 2e-17 63.8 0.0 3.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEY66212.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KEY66212.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KEY66212.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 KEY66213.1 - 9.7e-21 74.7 0.0 3.8e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NPP1 PF05630.11 KEY66215.1 - 9.6e-57 192.3 0.0 1.1e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) COesterase PF00135.28 KEY66216.1 - 3.4e-73 247.3 0.0 2e-66 224.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY66216.1 - 6.7e-06 26.1 0.1 2.1e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold He_PIG PF05345.12 KEY66216.1 - 0.013 15.6 0.4 0.059 13.6 0.4 2.1 1 0 0 1 1 1 0 Putative Ig domain ADH_zinc_N PF00107.26 KEY66217.1 - 1e-06 28.8 0.2 2.1e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY66217.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DJ-1_PfpI PF01965.24 KEY66218.1 - 2.3e-10 40.5 0.0 2.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2_4 PF13894.6 KEY66219.1 - 0.00036 21.1 8.4 0.027 15.3 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEY66219.1 - 0.0007 19.9 4.5 0.0011 19.3 4.5 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KEY66219.1 - 0.023 15.0 0.1 0.023 15.0 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KEY66219.1 - 0.024 14.9 0.0 0.024 14.9 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY66219.1 - 0.31 11.5 4.4 1.5 9.4 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PT PF04886.12 KEY66220.1 - 0.041 13.4 0.0 0.041 13.4 0.0 3.9 4 0 0 4 4 4 0 PT repeat ECM11 PF15463.6 KEY66222.1 - 0.51 10.9 2.9 0.89 10.1 0.2 2.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 UPF0261 PF06792.11 KEY66223.1 - 1.8e-164 547.5 0.2 2e-164 547.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PrpR_N PF06506.11 KEY66223.1 - 0.027 14.0 0.0 2.4 7.7 0.0 2.5 2 1 0 2 2 2 0 Propionate catabolism activator PEP_hydrolase PF09370.10 KEY66224.1 - 2.6e-135 449.8 0.3 2.9e-135 449.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KEY66224.1 - 6.7e-05 22.4 0.2 9.4e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase GFO_IDH_MocA PF01408.22 KEY66225.1 - 5.3e-18 66.0 0.1 1.2e-17 64.9 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KEY66225.1 - 4.7e-05 23.5 0.1 0.002 18.3 0.1 2.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KEY66225.1 - 0.0031 18.2 0.1 0.0059 17.3 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KEY66225.1 - 0.039 14.4 0.1 0.19 12.2 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 KEY66226.1 - 1e-05 25.5 6.1 2.1e-05 24.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HB_MCP_1 PF12729.7 KEY66227.1 - 0.22 11.0 9.4 0.13 11.8 1.3 3.3 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction Imm30 PF15565.6 KEY66227.1 - 2.9 8.0 6.7 4.1 7.5 0.2 3.0 2 1 1 3 3 3 0 Immunity protein 30 BTB PF00651.31 KEY66228.1 - 1.3e-15 57.5 0.0 6.1e-14 52.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Sif PF06767.11 KEY66228.1 - 0.014 14.4 0.2 0.033 13.2 0.1 1.4 1 1 0 1 1 1 0 Sif protein BACK PF07707.15 KEY66228.1 - 0.019 15.1 1.3 1.8 8.7 0.1 2.6 1 1 1 2 2 2 0 BTB And C-terminal Kelch Sec8_exocyst PF04048.14 KEY66228.1 - 0.11 12.4 3.7 0.076 12.9 1.1 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TGF_beta_GS PF08515.12 KEY66228.1 - 0.55 9.8 2.1 1.2 8.7 2.1 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif P-mevalo_kinase PF04275.14 KEY66229.1 - 5.1e-23 81.2 0.0 1.1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 KEY66229.1 - 2.7e-21 75.7 0.0 4.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 KEY66229.1 - 4.6e-13 49.1 4.3 8.9e-13 48.2 3.6 1.9 2 0 0 2 2 2 1 FAD binding domain UPRTase PF14681.6 KEY66229.1 - 0.0019 17.7 0.1 0.0038 16.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 KEY66229.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PRTase_2 PF15609.6 KEY66229.1 - 0.017 14.6 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase Methyltransf_23 PF13489.6 KEY66229.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GTP_cyclohydroI PF01227.22 KEY66230.1 - 4e-50 169.7 0.0 5.3e-38 130.2 0.1 2.2 1 1 1 2 2 2 2 GTP cyclohydrolase I DUF2075 PF09848.9 KEY66231.1 - 1.9e-56 191.9 0.0 2.7e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Hydrolase_6 PF13344.6 KEY66231.1 - 3.7e-25 88.0 0.0 1.4e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MazG-like PF12643.7 KEY66231.1 - 5.9e-16 58.5 0.0 1.3e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 MazG-like family Hydrolase_like PF13242.6 KEY66231.1 - 1.6e-15 56.9 0.0 5.4e-15 55.2 0.0 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY66231.1 - 0.0015 18.8 0.0 6.7 6.9 0.0 3.7 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase MazG PF03819.17 KEY66231.1 - 0.002 18.3 0.1 0.004 17.3 0.1 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain AAA_22 PF13401.6 KEY66231.1 - 0.0035 17.6 0.1 0.027 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 KEY66231.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 KEY66231.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain ResIII PF04851.15 KEY66231.1 - 0.017 15.2 0.0 0.9 9.5 0.0 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KEY66231.1 - 0.023 15.1 0.1 0.085 13.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 KEY66231.1 - 0.025 14.3 0.1 0.11 12.2 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KEY66231.1 - 0.11 12.8 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pectate_lyase PF03211.13 KEY66232.1 - 6.8e-80 267.4 8.3 9.4e-80 266.9 8.3 1.1 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_28 PF00295.17 KEY66233.1 - 6.5e-35 120.7 2.5 9.6e-35 120.2 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KEY66233.1 - 0.75 9.6 17.5 0.11 12.3 10.5 2.4 1 1 1 2 2 2 0 Right handed beta helix region Glyco_hydro_12 PF01670.16 KEY66234.1 - 5.1e-67 226.0 13.3 5.9e-67 225.8 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Fungal_trans PF04082.18 KEY66236.1 - 3.7e-16 58.9 2.6 5.8e-16 58.3 1.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66236.1 - 9.3e-08 32.1 11.8 1.6e-07 31.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HyaE PF07449.11 KEY66236.1 - 0.11 12.5 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE HET PF06985.11 KEY66237.1 - 6.3e-18 65.5 0.1 1.1e-17 64.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY66238.1 - 7.4e-36 123.7 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KEY66239.1 - 5.4e-77 259.5 0.0 6.9e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.6 KEY66239.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF2931 PF11153.8 KEY66240.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) MFS_2 PF13347.6 KEY66241.1 - 0.0088 14.6 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein OSCP PF00213.18 KEY66241.1 - 0.085 13.0 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF4381 PF14316.6 KEY66241.1 - 0.11 12.8 4.2 0.15 12.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Rep_fac-A_3 PF08661.11 KEY66243.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 RhoGAP PF00620.27 KEY66244.1 - 1.3e-08 34.8 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PKcGMP_CC PF16808.5 KEY66244.1 - 0.061 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase T2SSF PF00482.23 KEY66244.1 - 0.19 11.7 0.5 0.46 10.5 0.5 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Efg1 PF10153.9 KEY66244.1 - 4.1 7.8 4.9 12 6.3 4.9 1.8 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DHR10 PF18595.1 KEY66244.1 - 6.3 6.9 15.3 2.3 8.3 0.4 2.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FUSC PF04632.12 KEY66244.1 - 8.1 4.8 16.0 0.099 11.2 8.1 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4072 PF13284.6 KEY66244.1 - 8.5 6.9 7.7 0.85 10.1 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) CBS PF00571.28 KEY66245.1 - 9.4e-29 99.6 6.8 7.2e-11 42.4 0.4 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.23 KEY66246.1 - 3.7e-77 252.3 33.9 1.5e-13 50.3 0.1 11.1 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEY66246.1 - 4.2e-20 71.8 9.5 0.00015 22.2 0.3 8.1 6 2 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KEY66246.1 - 6.4e-18 64.9 8.0 3.9e-05 23.9 0.1 6.7 3 3 3 7 7 7 5 HEAT repeats HEAT PF02985.22 KEY66246.1 - 3.4e-15 54.8 16.8 0.068 13.5 0.3 8.9 10 0 0 10 10 9 5 HEAT repeat Adaptin_N PF01602.20 KEY66246.1 - 2e-12 46.5 7.9 3.1e-07 29.4 0.3 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KEY66246.1 - 4.8e-11 42.6 5.5 1.4e-07 31.3 1.3 2.7 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 KEY66246.1 - 2.3e-09 36.0 0.6 4.6e-09 35.0 0.6 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KEY66246.1 - 2.5e-09 36.9 1.4 1.6e-05 24.4 0.8 3.0 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KEY66246.1 - 5.7e-05 23.2 8.0 0.058 13.4 0.3 4.8 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KEY66246.1 - 7.5e-05 22.7 6.6 1.5 8.7 0.1 4.2 1 1 2 4 4 4 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KEY66246.1 - 0.00011 22.2 0.6 24 5.1 0.0 4.9 2 1 5 7 7 7 0 V-ATPase subunit H DUF5578 PF17741.1 KEY66246.1 - 0.00021 20.8 5.3 1.4 8.3 0.0 4.8 2 2 3 5 5 5 2 Family of unknown function (DUF5578) IFRD PF05004.13 KEY66246.1 - 0.00061 19.0 2.8 1.3 8.0 0.1 3.9 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KEY66246.1 - 0.0025 18.3 4.8 38 5.3 0.1 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KEY66246.1 - 0.0064 16.5 0.4 1.4 8.9 0.1 3.4 2 1 1 3 3 3 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KEY66246.1 - 0.051 14.2 0.1 5.7 7.6 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KEY66246.1 - 0.06 13.4 6.1 5.1 7.2 0.1 4.1 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Peptidase_S24 PF00717.23 KEY66247.1 - 9.4e-05 22.3 0.1 0.00018 21.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KEY66247.1 - 0.044 13.6 0.0 1.6 8.6 0.0 2.4 2 1 0 2 2 2 0 Signal peptidase, peptidase S26 IF3_C PF00707.22 KEY66248.1 - 1.3e-07 31.4 0.4 2.2e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KEY66248.1 - 9.3e-06 25.4 2.0 1.2e-05 25.1 1.5 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor ODR4-like PF14778.6 KEY66248.1 - 0.021 13.8 0.2 0.028 13.4 0.2 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like Alb1 PF09135.11 KEY66249.1 - 1.2e-27 96.8 13.5 1.7e-27 96.3 13.5 1.2 1 0 0 1 1 1 1 Alb1 MRP-S26 PF14943.6 KEY66249.1 - 0.018 15.0 1.2 0.027 14.4 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Amidase PF01425.21 KEY66250.1 - 2.3e-11 43.4 0.0 4.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Amidase 2-Hacid_dh_C PF02826.19 KEY66251.1 - 1.4e-32 112.5 0.0 2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY66251.1 - 2.6e-11 43.3 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEY66251.1 - 0.037 14.2 0.0 0.072 13.3 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HAT_KAT11 PF08214.11 KEY66252.1 - 3.2e-91 306.2 0.0 4.7e-91 305.7 0.0 1.3 1 1 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.6 KEY66253.1 - 1.7e-22 79.9 0.0 3.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like DUF373 PF04123.13 KEY66254.1 - 2.3 7.5 6.1 1.8 7.9 4.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) CorA PF01544.18 KEY66257.1 - 4.4e-12 45.9 1.4 7.5e-12 45.2 0.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KEY66257.1 - 0.00035 20.1 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY66257.1 - 0.0006 20.5 5.0 0.0006 20.5 5.0 3.6 1 1 3 4 4 4 1 Alpha/beta hydrolase family Ribosomal_L27 PF01016.19 KEY66259.1 - 9.5e-26 89.6 0.0 9.5e-26 89.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein DUF2076 PF09849.9 KEY66260.1 - 0.0082 16.2 0.2 0.0082 16.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) IPP-2 PF04979.14 KEY66261.1 - 6.3e-24 85.2 6.1 6.3e-24 85.2 6.1 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) TFIIA PF03153.13 KEY66261.1 - 0.44 10.5 6.9 0.61 10.0 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 KEY66262.1 - 8.5e-16 57.8 25.1 5e-08 32.9 9.7 2.9 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY66262.1 - 1.4e-10 40.7 1.5 2.3e-10 40.0 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.20 KEY66263.1 - 2.8e-35 121.5 16.4 5.8e-30 104.2 0.0 3.4 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY66263.1 - 2.8e-27 95.6 6.9 2.8e-27 95.6 6.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY66263.1 - 9.2e-19 68.6 0.0 2.2e-17 64.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY66263.1 - 1.9e-16 59.9 0.0 4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEY66263.1 - 6.2e-16 57.9 0.6 1.4e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY66263.1 - 0.0006 19.6 0.3 0.002 18.0 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KEY66265.1 - 4.4e-15 55.6 0.0 5.2e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66265.1 - 1.1e-10 41.5 0.1 1.3e-10 41.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66265.1 - 5.6e-05 23.1 0.1 7.3e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY66265.1 - 0.00027 20.9 0.9 0.00031 20.7 0.9 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY66265.1 - 0.01 15.3 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KEY66265.1 - 0.035 14.1 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 KEY66265.1 - 0.055 13.2 1.2 2.2 8.1 0.3 2.4 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.13 KEY66266.1 - 3.2e-40 138.1 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY66266.1 - 3.4e-12 46.6 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY66266.1 - 1.3e-05 24.4 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY66266.1 - 6.9e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acid_PPase PF12689.7 KEY66267.1 - 3.9e-62 209.0 0.0 4.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase UPF0121 PF03661.13 KEY66268.1 - 3.4e-29 101.9 4.0 4.6e-29 101.5 4.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.20 KEY66269.1 - 2.3e-10 40.4 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEY66269.1 - 0.0054 16.3 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KEY66269.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.9 KEY66269.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Zn_clus PF00172.18 KEY66270.1 - 9.6e-05 22.4 15.5 0.00016 21.8 15.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY66270.1 - 0.059 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain HA2 PF04408.23 KEY66271.1 - 3.1e-23 82.1 0.1 3.1e-23 82.1 0.1 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY66271.1 - 2.5e-22 79.0 0.0 4.8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEY66271.1 - 2.2e-13 50.5 0.0 5.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KEY66271.1 - 2.8e-09 37.2 0.3 6.1e-09 36.1 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KEY66271.1 - 7.6e-06 26.2 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KEY66271.1 - 8.4e-06 25.7 0.5 2.4e-05 24.2 0.5 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KEY66271.1 - 1.5e-05 24.8 0.1 5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEY66271.1 - 5.7e-05 22.3 0.1 0.00016 20.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KEY66271.1 - 0.0035 17.7 0.1 0.008 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEY66271.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KEY66271.1 - 0.04 13.9 0.3 0.39 10.7 0.1 2.5 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 KEY66271.1 - 0.049 13.1 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KEY66271.1 - 0.065 13.7 0.2 0.37 11.3 0.2 2.3 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KEY66271.1 - 0.093 12.3 0.1 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KEY66271.1 - 0.15 10.9 0.1 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KEY66271.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 KEY66271.1 - 0.17 11.1 0.1 0.41 9.8 0.1 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Myosin_head PF00063.21 KEY66271.1 - 0.19 9.9 0.1 0.33 9.1 0.1 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Ank_2 PF12796.7 KEY66272.1 - 1.7e-34 118.2 4.4 6.2e-10 39.5 0.1 7.4 4 2 6 10 10 10 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY66272.1 - 4.7e-25 87.3 3.5 2.4e-06 27.7 0.1 7.4 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY66272.1 - 5e-25 87.5 6.2 2.3e-07 31.2 0.0 9.2 7 1 2 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66272.1 - 5.7e-19 66.2 2.9 0.1 13.2 0.0 10.5 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 KEY66272.1 - 5e-12 45.7 11.8 0.79 10.3 0.1 10.4 11 1 0 11 11 11 4 Ankyrin repeat Cellulase PF00150.18 KEY66273.1 - 6.1e-40 137.4 0.2 1e-39 136.7 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KEY66273.1 - 2.4e-15 56.4 0.0 3.1e-11 43.2 0.0 2.9 2 1 0 2 2 2 2 Carbohydrate binding domain X2 zf_CCCH_4 PF18345.1 KEY66274.1 - 9.2e-12 44.6 15.9 1.1e-06 28.5 4.3 3.2 3 0 0 3 3 3 2 Zinc finger domain IBR PF01485.21 KEY66274.1 - 1.1e-11 44.8 33.3 1.1e-07 31.9 0.5 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 KEY66274.1 - 9.2e-10 38.2 10.0 7.8e-05 22.5 4.0 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEY66274.1 - 3.5e-09 37.3 2.8 0.00032 21.4 0.0 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KEY66274.1 - 2.9e-08 33.3 19.3 1.4e-05 24.7 2.6 3.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf-C3HC4_3 PF13920.6 KEY66274.1 - 5.8e-05 22.9 8.0 5.8e-05 22.9 8.0 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_3 PF15663.5 KEY66274.1 - 0.01 16.0 8.6 0.76 10.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger containing family zf-C3HC4 PF00097.25 KEY66274.1 - 0.013 15.4 12.2 0.013 15.4 12.2 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KEY66274.1 - 0.19 12.3 24.1 0.093 13.2 1.1 4.1 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger YhfH PF14149.6 KEY66274.1 - 0.2 11.7 7.8 0.3 11.1 4.9 2.7 2 0 0 2 2 2 0 YhfH-like protein MFS_1 PF07690.16 KEY66275.1 - 1.3e-35 123.0 52.4 2.1e-25 89.4 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 KEY66275.1 - 0.004 17.2 1.0 0.44 10.6 0.1 2.4 2 0 0 2 2 2 2 PgaD-like protein ANAPC4_WD40 PF12894.7 KEY66276.1 - 4.6e-09 36.4 0.0 0.021 15.1 0.0 3.9 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY66276.1 - 6.7e-05 22.9 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PQQ_3 PF13570.6 KEY66276.1 - 0.011 16.2 0.4 7.7 7.1 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 KEY66276.1 - 0.025 13.9 0.0 5.8 6.1 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KEY66276.1 - 0.087 13.7 3.3 0.76 10.8 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Fructosamin_kin PF03881.14 KEY66277.1 - 2.4e-30 105.8 0.0 2.9e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEY66277.1 - 4.3e-06 26.8 0.3 7.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KEY66279.1 - 4.8e-08 32.9 0.0 7.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66279.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66279.1 - 0.00011 22.1 0.1 0.00051 20.0 0.0 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY66279.1 - 0.012 15.1 0.0 0.042 13.3 0.0 1.9 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Helo_like_N PF17111.5 KEY66279.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins MFS_1 PF07690.16 KEY66280.1 - 2.5e-43 148.4 40.7 1.1e-39 136.3 22.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KEY66281.1 - 6.4e-07 29.6 0.0 9.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY66281.1 - 4.6e-05 23.8 0.0 8.1e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY66281.1 - 0.0033 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY66281.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KEY66281.1 - 0.068 13.2 0.0 0.28 11.3 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Amdase PF17645.1 KEY66281.1 - 0.085 12.5 0.0 9.7 5.7 0.0 2.1 1 1 1 2 2 2 0 Arylmalonate decarboxylase Peptidase_M14 PF00246.24 KEY66282.1 - 9.6e-13 48.6 0.0 2.7e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KEY66282.1 - 0.0025 16.9 0.3 0.012 14.8 0.0 2.2 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 KEY66282.1 - 0.025 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) SMODS PF18144.1 KEY66282.1 - 0.072 13.3 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Anoctamin PF04547.12 KEY66283.1 - 4.3e-99 332.4 4.9 5.3e-99 332.1 4.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel YitT_membrane PF02588.15 KEY66283.1 - 4 6.7 7.7 0.29 10.4 0.6 2.6 3 0 0 3 3 3 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Glyco_hydro_10 PF00331.20 KEY66284.1 - 2.3e-84 283.2 0.0 2.6e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ribonuclease PF00545.20 KEY66284.1 - 0.04 14.7 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 ribonuclease SNF2_N PF00176.23 KEY66286.1 - 1.2e-44 152.4 0.0 5e-44 150.5 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEY66286.1 - 1.8e-09 37.9 0.0 5.2e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY66286.1 - 1.8e-09 37.9 0.0 4.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KEY66286.1 - 6.1e-05 22.8 4.5 0.00014 21.6 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY66286.1 - 6.3e-05 22.7 1.6 0.00015 21.6 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY66286.1 - 0.0018 18.3 4.7 0.0046 16.9 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KEY66286.1 - 0.022 14.6 2.8 0.058 13.2 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KEY66286.1 - 0.023 14.7 5.9 0.052 13.5 5.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KEY66286.1 - 0.087 13.2 6.2 0.2 12.0 6.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KEY66286.1 - 0.22 11.7 3.3 0.59 10.3 3.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KEY66286.1 - 0.27 11.3 6.3 0.36 10.9 1.9 2.6 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_3 PF13920.6 KEY66286.1 - 0.75 9.7 5.4 2 8.4 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Gal4_dimer PF03902.13 KEY66286.1 - 1.3 9.2 4.4 0.92 9.7 0.3 2.7 3 1 0 3 3 3 0 Gal4-like dimerisation domain Git3 PF11710.8 KEY66288.1 - 2.6e-50 171.0 12.9 4.2e-50 170.3 12.9 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KEY66288.1 - 6e-12 45.5 0.0 2.1e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KEY66288.1 - 6.6e-05 22.4 0.1 0.00016 21.1 0.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serglycin PF04360.12 KEY66288.1 - 0.03 14.3 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 Serglycin Fungus-induced PF10917.8 KEY66288.1 - 0.29 11.5 1.0 2.3 8.6 0.2 2.9 3 0 0 3 3 3 0 Fungus-induced protein GATase PF00117.28 KEY66289.1 - 2.7e-08 33.8 0.0 3.5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KEY66289.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Beta-lactamase PF00144.24 KEY66290.1 - 1.8e-36 126.1 0.1 2.4e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.15 KEY66290.1 - 0.043 12.5 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 KEY66290.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DHHA2 PF02833.14 KEY66291.1 - 1.2e-38 132.5 0.2 1.8e-38 131.9 0.2 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KEY66291.1 - 1.3e-08 35.0 0.0 2.4e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 DHH family RsfS PF02410.15 KEY66292.1 - 1.4e-11 44.7 0.0 5.2e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Moulting_cycle PF04870.16 KEY66292.1 - 1.6 8.0 4.3 1.3 8.2 1.3 2.0 2 0 0 2 2 2 0 Moulting cycle RNA_pol PF00940.19 KEY66293.1 - 1.2e-183 610.7 0.0 1.7e-183 610.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KEY66293.1 - 1.4e-95 320.5 3.8 2.2e-95 319.9 3.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Exonuc_X-T_C PF08411.10 KEY66293.1 - 0.11 11.7 0.0 0.31 10.1 0.0 1.8 1 0 0 1 1 1 0 Exonuclease C-terminal tRNA_bind PF01588.20 KEY66294.1 - 1.5e-21 76.3 0.1 3.7e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KEY66294.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY66294.1 - 0.00058 20.0 1.6 0.011 15.9 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pol_alpha_B_N PF08418.10 KEY66294.1 - 0.00099 19.1 0.8 0.095 12.7 0.2 2.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal DUF2486 PF10667.9 KEY66294.1 - 0.56 10.4 13.1 0.87 9.8 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) SNF2_N PF00176.23 KEY66295.1 - 1.1e-66 224.9 0.1 2.3e-66 223.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY66295.1 - 7.8e-22 77.7 0.0 2.6e-21 76.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY66295.1 - 3.6e-09 36.8 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEY66295.1 - 6.4e-06 25.6 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KEY66295.1 - 0.0043 16.3 3.7 0.0069 15.6 0.0 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Ank_2 PF12796.7 KEY66296.1 - 3.9e-37 126.7 12.6 7.5e-07 29.7 0.0 14.1 8 5 9 17 17 17 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY66296.1 - 1.3e-22 79.8 16.7 0.007 16.9 0.0 14.9 15 2 2 17 17 17 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66296.1 - 8e-18 62.7 14.2 0.17 12.5 0.0 17.1 19 0 0 19 19 19 2 Ankyrin repeat Ank_5 PF13857.6 KEY66296.1 - 5.7e-12 45.6 8.7 1.6e-05 25.0 0.0 8.8 9 1 1 10 10 10 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY66296.1 - 5.9e-12 45.5 29.8 0.00083 19.7 0.0 15.3 16 4 2 18 18 18 3 Ankyrin repeat Abhydrolase_1 PF00561.20 KEY66297.1 - 1.1e-21 77.7 0.0 1.2e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY66297.1 - 1.2e-17 65.3 1.4 1.5e-17 65.0 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY66297.1 - 3e-07 30.0 0.0 5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KEY66297.1 - 0.03 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KEY66297.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme ADH_zinc_N PF00107.26 KEY66298.1 - 1.3e-27 96.4 0.1 2.4e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY66298.1 - 3.3e-18 67.0 0.1 8.5e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY66298.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEY66298.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ApbA PF02558.16 KEY66298.1 - 0.032 13.9 0.1 0.072 12.7 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KEY66298.1 - 0.063 12.7 0.4 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 KEY66299.1 - 4.3e-46 157.3 0.0 5.5e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY66299.1 - 2.6e-45 155.3 0.0 5.5e-45 154.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY66299.1 - 6.1e-16 58.2 0.0 2.6e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEY66299.1 - 4.1e-12 45.8 0.0 5.9e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEY66299.1 - 1.7e-10 40.5 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KEY66299.1 - 2.5e-08 33.6 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66299.1 - 7.8e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KEY66299.1 - 1.2e-05 24.7 0.1 0.00023 20.4 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KEY66299.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KEY66299.1 - 0.0051 16.4 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KEY66299.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KEY66299.1 - 0.038 13.5 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KEY66299.1 - 0.046 13.3 0.2 0.081 12.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sad1_UNC PF07738.13 KEY66300.1 - 2.4e-05 24.3 0.0 0.00034 20.6 0.0 2.3 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal Rsa3 PF14615.6 KEY66300.1 - 0.047 13.3 0.6 0.14 11.7 0.0 2.1 3 0 0 3 3 3 0 Ribosome-assembly protein 3 DUF1216 PF06746.11 KEY66300.1 - 0.16 12.0 0.9 0.86 9.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) DEAD PF00270.29 KEY66301.1 - 1.2e-45 155.4 0.8 2.7e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY66301.1 - 9.5e-25 87.1 0.0 4.3e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEY66301.1 - 4.3e-22 78.1 0.0 1.2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEY66301.1 - 2.6e-06 27.5 1.5 5.4e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PIN_3 PF13470.6 KEY66301.1 - 3 8.6 6.1 54 4.6 0.5 4.0 4 1 0 4 4 4 0 PIN domain Glyco_hydro_17 PF00332.18 KEY66302.1 - 7.3e-08 32.4 0.3 1.4e-07 31.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 BUD22 PF09073.10 KEY66302.1 - 3.1 7.0 6.4 4.2 6.6 6.4 1.1 1 0 0 1 1 1 0 BUD22 DUF588 PF04535.12 KEY66303.1 - 0.053 13.3 3.3 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF588) Phage_holin_3_6 PF07332.11 KEY66303.1 - 0.47 10.5 5.9 0.29 11.2 0.4 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III AMP-binding PF00501.28 KEY66304.1 - 2.4e-72 243.8 0.0 2.4e-72 243.8 0.0 1.8 3 0 0 3 3 3 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY66304.1 - 6e-05 23.9 0.0 0.00014 22.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RGS PF00615.19 KEY66305.1 - 0.012 15.8 0.0 0.038 14.3 0.0 1.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain Remorin_C PF03763.13 KEY66305.1 - 0.13 12.1 0.3 0.24 11.3 0.3 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region DUF4267 PF14087.6 KEY66306.1 - 0.00013 22.0 2.0 0.00021 21.3 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Methyltransf_23 PF13489.6 KEY66307.1 - 2.6e-09 37.1 0.0 7.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain HTH_51 PF18558.1 KEY66307.1 - 0.094 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NUC153 PF08159.12 KEY66308.1 - 3.7e-15 55.4 1.6 3.7e-15 55.4 1.6 3.4 3 0 0 3 3 3 2 NUC153 domain Sperm_act_pep PF08250.11 KEY66309.1 - 3.7 8.3 7.1 13 6.6 7.1 2.0 1 0 0 1 1 1 0 Sperm-activating peptides DUF2781 PF10914.8 KEY66310.1 - 3.5e-31 108.6 5.2 3.9e-31 108.4 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DctQ PF04290.12 KEY66310.1 - 0.029 14.3 0.0 0.088 12.7 0.0 1.9 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Iso_dh PF00180.20 KEY66311.1 - 3.6e-71 240.1 0.0 5.7e-71 239.5 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KEY66312.1 - 4.5e-36 124.5 36.0 4.5e-36 124.5 36.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66312.1 - 2.2e-11 43.3 9.7 2.2e-11 43.3 9.7 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter FA_desaturase PF00487.24 KEY66312.1 - 0.13 12.1 28.6 0.61 9.9 7.5 4.0 1 1 4 5 5 5 0 Fatty acid desaturase Nucleoporin_N PF08801.11 KEY66313.1 - 6.3e-100 335.0 0.1 9.6e-100 334.3 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KEY66313.1 - 1.8e-49 169.0 0.1 3.4e-48 164.8 0.0 2.2 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Phasin_2 PF09361.10 KEY66313.1 - 0.055 13.7 0.2 0.3 11.4 0.1 2.3 2 0 0 2 2 2 0 Phasin protein adh_short PF00106.25 KEY66314.1 - 8.5e-33 113.5 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66314.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66314.1 - 6.9e-05 22.8 0.0 0.00016 21.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KEY66314.1 - 0.0048 16.1 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Erg28 PF03694.13 KEY66315.1 - 6.9e-45 152.0 0.5 8.5e-45 151.7 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KEY66316.1 - 3e-69 233.1 0.2 8.2e-68 228.5 0.1 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KEY66316.1 - 5.8e-61 205.1 0.1 1.2e-60 204.0 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KEY66316.1 - 0.0017 19.0 0.0 0.0062 17.2 0.0 2.0 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KEY66316.1 - 0.051 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Myb_DNA-binding PF00249.31 KEY66317.1 - 5.6e-09 36.1 0.6 3e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM PF04433.17 KEY66317.1 - 6.6e-08 32.8 0.0 2.2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 KEY66317.1 - 0.0002 21.1 7.4 0.00076 19.2 2.3 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type Rhodanese PF00581.20 KEY66318.1 - 6.1e-14 52.4 0.0 8.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HD_3 PF13023.6 KEY66319.1 - 4.4e-49 166.6 0.0 5.6e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KEY66319.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme CRAL_TRIO_N PF03765.15 KEY66319.1 - 0.19 12.0 0.9 22 5.3 0.0 2.5 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain SPX PF03105.19 KEY66320.1 - 0.08 12.9 8.6 0.15 11.9 8.6 1.4 1 0 0 1 1 1 0 SPX domain WSC PF01822.19 KEY66321.1 - 6.1e-12 45.6 7.0 1.3e-11 44.6 7.0 1.5 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.11 KEY66321.1 - 8.8e-06 25.9 0.7 1.8e-05 24.9 0.7 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KEY66321.1 - 0.00019 20.4 0.5 0.00019 20.4 0.5 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein Syndecan PF01034.20 KEY66321.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KEY66321.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 KEY66321.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TraL PF07178.11 KEY66321.1 - 0.17 12.4 0.2 0.31 11.5 0.2 1.4 1 0 0 1 1 1 0 TraL protein EphA2_TM PF14575.6 KEY66321.1 - 0.17 12.7 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PSP PF04046.16 KEY66321.1 - 0.23 11.4 0.2 0.69 9.8 0.1 1.8 2 0 0 2 2 2 0 PSP THOC2_N PF16134.5 KEY66322.1 - 5.2e-242 805.0 0.0 7.2e-242 804.5 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KEY66322.1 - 4.4e-89 298.7 0.0 8.6e-89 297.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KEY66322.1 - 2.2e-26 91.7 0.2 4.6e-26 90.7 0.2 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 KEY66324.1 - 1.6e-48 165.6 0.0 4.6e-48 164.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY66324.1 - 0.001 19.7 5.9 0.0055 17.3 5.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kelch_5 PF13854.6 KEY66326.1 - 9.5e-05 22.3 0.3 0.69 10.0 0.0 3.1 3 0 0 3 3 3 2 Kelch motif MLANA PF14991.6 KEY66326.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A Kelch_2 PF07646.15 KEY66326.1 - 0.0031 17.4 0.5 0.85 9.7 0.1 3.7 3 0 0 3 3 3 1 Kelch motif DUF4381 PF14316.6 KEY66326.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RSN1_7TM PF02714.15 KEY66327.1 - 1.2e-84 283.8 31.4 8e-84 281.2 28.5 2.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY66327.1 - 1e-43 148.8 2.4 1e-43 148.8 2.4 2.9 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEY66327.1 - 2.3e-34 119.2 0.0 3.3e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEY66327.1 - 5.5e-33 113.0 0.3 2.1e-32 111.1 0.1 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 KEY66327.1 - 0.036 14.4 0.1 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF4407 PF14362.6 KEY66328.1 - 0.025 14.0 3.8 0.034 13.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Radical_SAM PF04055.21 KEY66329.1 - 7e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEY66329.1 - 0.0001 22.6 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEY66329.1 - 0.051 13.7 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1681 PF07933.14 KEY66331.1 - 1.2e-55 187.3 0.0 1.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IF-2B PF01008.17 KEY66332.1 - 1.2e-45 155.9 0.1 1.4e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family SpoU_sub_bind PF08032.12 KEY66332.1 - 0.15 12.4 0.0 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Methyltransf_33 PF10017.9 KEY66333.1 - 1.2e-51 175.7 0.0 3.5e-36 124.9 0.0 2.2 1 1 1 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KEY66333.1 - 4.5e-16 59.2 0.6 4e-09 36.4 0.1 2.6 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KEY66333.1 - 1.2e-05 25.8 0.3 3.4e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 DinB superfamily Fungal_trans PF04082.18 KEY66334.1 - 1.3e-13 50.6 0.0 2.6e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66334.1 - 9.2e-08 32.1 6.6 1.7e-07 31.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_2 PF13279.6 KEY66335.1 - 5.6e-20 72.1 0.0 9.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3135 PF11333.8 KEY66335.1 - 0.12 12.6 0.8 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Senescence PF06911.12 KEY66336.1 - 7.5e-50 169.8 7.1 1.1e-49 169.3 7.1 1.2 1 0 0 1 1 1 1 Senescence-associated protein GCP_C_terminal PF04130.13 KEY66337.1 - 1.1e-23 84.2 0.0 3.6e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEY66337.1 - 1.8e-23 83.6 0.0 3.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal MRI PF15325.6 KEY66338.1 - 7.6 7.7 13.3 4.7 8.4 4.4 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection SH3_1 PF00018.28 KEY66341.1 - 1.1e-11 44.1 0.3 1.1e-11 44.1 0.3 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KEY66341.1 - 9.6e-10 38.2 0.2 2.3e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY66341.1 - 1.4e-09 37.5 0.0 8.6e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DNase-RNase PF02577.14 KEY66341.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease Pkinase PF00069.25 KEY66342.1 - 3.1e-16 59.5 0.0 9.7e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66342.1 - 0.00016 21.0 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY66342.1 - 0.0013 18.7 0.0 1.6 8.5 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Bin3 PF06859.12 KEY66342.1 - 0.069 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Phasin_2 PF09361.10 KEY66343.1 - 0.026 14.8 0.0 9.5 6.6 0.1 2.5 1 1 1 2 2 2 0 Phasin protein ArsR PF09824.9 KEY66343.1 - 0.11 12.1 0.4 4.4 6.9 0.1 2.4 1 1 1 2 2 2 0 ArsR transcriptional regulator MIR PF02815.19 KEY66343.1 - 0.11 12.3 0.8 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 MIR domain CorA PF01544.18 KEY66343.1 - 0.17 11.2 7.9 1.6 8.0 0.5 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RPAP2_Rtr1 PF04181.13 KEY66344.1 - 8.8e-20 70.8 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Mit_ribos_Mrp51 PF11709.8 KEY66345.1 - 4.8e-119 398.2 0.0 5.7e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.18 KEY66346.1 - 8.6e-143 475.7 0.0 1e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.19 KEY66347.1 - 4.1e-52 177.6 0.1 6.5e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.19 KEY66348.1 - 1.3e-13 51.6 0.0 2.3e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 PHP domain DUF3433 PF11915.8 KEY66349.1 - 2.4e-27 95.2 11.5 3.2e-16 59.5 2.0 4.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) RskA PF10099.9 KEY66349.1 - 1.1 9.5 5.1 4.3 7.6 1.1 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Fumarate_red_C PF02300.17 KEY66349.1 - 2 8.5 8.2 5.9 7.0 0.2 2.9 3 0 0 3 3 3 0 Fumarate reductase subunit C ABC_tran PF00005.27 KEY66350.1 - 2.3e-49 167.4 0.4 1.5e-26 93.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KEY66350.1 - 1.7e-26 93.1 24.1 1.9e-16 60.2 16.3 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KEY66350.1 - 1.3e-20 74.4 6.6 4.7e-05 23.4 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY66350.1 - 1.3e-08 34.5 2.1 0.00044 19.9 0.8 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KEY66350.1 - 1.2e-07 31.4 2.9 0.12 11.8 0.4 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEY66350.1 - 5e-06 27.2 4.3 0.04 14.4 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEY66350.1 - 8.1e-05 22.5 0.3 0.38 10.4 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 KEY66350.1 - 0.00029 20.5 1.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY66350.1 - 0.001 19.0 1.9 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KEY66350.1 - 0.0035 17.1 2.4 1.5 8.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEY66350.1 - 0.0043 17.5 0.1 3.7 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY66350.1 - 0.02 15.2 0.2 6.6 7.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEY66350.1 - 0.048 13.6 0.1 9.2 6.1 0.1 2.8 2 1 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 KEY66350.1 - 0.051 13.8 0.2 39 4.6 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KEY66350.1 - 0.06 13.0 0.3 10 5.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KEY66350.1 - 0.086 12.1 0.3 11 5.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KEY66350.1 - 0.087 13.1 0.3 14 5.9 0.4 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEY66350.1 - 0.12 12.9 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KEY66350.1 - 0.12 12.1 0.6 18 5.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA PF00004.29 KEY66350.1 - 0.13 12.7 0.0 24 5.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEY66350.1 - 0.2 12.2 0.0 46 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEY66350.1 - 0.42 10.7 2.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AIG1 PF04548.16 KEY66350.1 - 1 8.7 2.1 4.3 6.6 0.5 2.2 2 0 0 2 2 2 0 AIG1 family bZIP_1 PF00170.21 KEY66351.1 - 0.00019 21.5 2.9 0.00019 21.5 2.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY66351.1 - 0.0094 16.0 3.4 0.021 14.9 3.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Exog_C PF18026.1 KEY66351.1 - 0.095 12.8 0.0 1.5 8.9 0.1 2.7 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain Hexapep PF00132.24 KEY66354.1 - 1.5e-12 46.7 6.8 3.6e-11 42.3 3.5 3.3 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEY66354.1 - 8e-12 44.7 6.5 2.5e-10 39.9 2.7 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KEY66354.1 - 2.8e-10 40.3 0.1 4.5e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase YABBY PF04690.13 KEY66355.1 - 0.087 13.4 0.6 0.11 13.1 0.6 1.3 1 1 0 1 1 1 0 YABBY protein DUF87 PF01935.17 KEY66355.1 - 0.17 11.9 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain PRP38 PF03371.15 KEY66356.1 - 2.9e-57 193.3 0.0 3.4e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Amidase PF01425.21 KEY66357.1 - 8.5e-112 374.4 0.0 1.3e-111 373.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Big_3_5 PF16640.5 KEY66357.1 - 0.061 13.5 1.6 0.13 12.4 1.6 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) SIP1 PF04938.12 KEY66358.1 - 6.3e-09 35.9 0.2 1.4e-07 31.5 0.1 2.7 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FHA PF00498.26 KEY66359.1 - 8.9e-18 64.4 0.1 3.6e-17 62.5 0.1 2.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEY66359.1 - 5e-05 23.5 0.0 0.00014 22.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KEY66359.1 - 0.0028 17.3 0.5 0.0061 16.1 0.0 1.7 2 0 0 2 2 2 1 YhfZ C-terminal domain Spc29 PF17082.5 KEY66359.1 - 0.46 10.3 6.6 0.054 13.3 0.6 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 Prefoldin PF02996.17 KEY66359.1 - 0.85 9.5 10.3 0.78 9.7 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 KEY66359.1 - 1.2 9.3 6.8 0.21 11.8 2.3 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 KEY66359.1 - 2.3 6.0 6.3 3.5 5.4 6.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Romo1 PF10247.9 KEY66360.1 - 6.6e-27 93.7 13.2 8.7e-27 93.3 13.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KEY66360.1 - 0.0038 17.6 4.9 0.0054 17.1 4.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cu-oxidase_3 PF07732.15 KEY66361.1 - 1.7e-42 144.2 7.9 3.6e-40 136.7 0.6 3.8 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KEY66361.1 - 1.9e-34 119.1 0.0 5e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEY66361.1 - 9.5e-33 112.8 12.8 7.4e-31 106.7 1.6 3.7 3 1 0 3 3 3 2 Multicopper oxidase SIR2 PF02146.17 KEY66362.1 - 9.3e-55 185.3 0.0 1.4e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family CAML PF14963.6 KEY66362.1 - 3.7 7.6 6.5 5.8 7.0 6.5 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MHYT PF03707.16 KEY66363.1 - 0.2 11.8 0.3 0.2 11.8 0.3 2.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat HET PF06985.11 KEY66364.1 - 1.6e-05 25.3 0.0 1.6e-05 25.3 0.0 3.2 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) ATP-synt_10 PF05176.14 KEY66364.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP10 protein zf-C2H2_4 PF13894.6 KEY66364.1 - 3.7 8.6 5.4 11 7.2 1.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Oxidored_FMN PF00724.20 KEY66365.1 - 1.1e-58 199.2 0.0 1.4e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pox_A6 PF04924.12 KEY66366.1 - 0.26 10.2 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein Methyltransf_23 PF13489.6 KEY66367.1 - 5.9e-12 45.7 0.0 8.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66367.1 - 4.9e-08 33.5 0.0 8.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66367.1 - 0.00024 21.7 0.0 0.00058 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY66367.1 - 0.0035 16.7 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEY66367.1 - 0.0039 17.9 0.0 0.0081 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66367.1 - 0.005 16.7 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY66367.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPR_12 PF13424.6 KEY66368.1 - 0.12 12.7 0.0 2.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KEY66369.1 - 1.2e-79 262.9 14.6 1.3e-13 51.3 0.3 6.8 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY66369.1 - 5.6e-52 173.5 7.4 3.6e-09 37.0 0.3 10.6 5 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KEY66369.1 - 4.9e-46 153.2 15.1 3.1e-06 27.4 0.3 12.9 12 1 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 KEY66369.1 - 3.1e-45 146.9 15.0 3.8e-05 23.7 0.1 13.9 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 KEY66369.1 - 7.6e-42 140.8 18.2 6.3e-12 45.5 0.5 10.6 2 2 8 11 11 11 10 Ankyrin repeats (many copies) Pkinase PF00069.25 KEY66369.1 - 3e-22 79.3 0.0 4.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66369.1 - 2e-18 66.6 0.0 3.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.6 KEY66370.1 - 2.4e-16 60.2 1.4 3.6e-16 59.6 1.4 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation YoqO PF14037.6 KEY66372.1 - 0.057 13.9 3.8 0.09 13.3 3.8 1.3 1 0 0 1 1 1 0 YoqO-like protein Pectate_lyase PF03211.13 KEY66373.1 - 1.9e-12 47.2 0.0 2.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase HET PF06985.11 KEY66375.1 - 6.7e-33 114.1 0.5 1.8e-32 112.7 0.5 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_38C PF07748.13 KEY66376.1 - 5.4e-56 190.0 0.2 8e-56 189.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 KEY66376.1 - 1.2e-41 143.0 0.1 1.1e-34 120.2 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KEY66376.1 - 2e-16 59.9 0.0 5.1e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KEY66376.1 - 1.4e-10 41.2 0.0 7.7e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Peptidase_S8 PF00082.22 KEY66377.1 - 1.4e-44 152.6 0.3 2.2e-44 151.9 0.3 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEY66377.1 - 3e-05 24.7 0.0 0.00011 22.8 0.0 2.0 2 0 0 2 2 2 1 Fn3-like domain Asparaginase_C PF17763.1 KEY66377.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain RPT PF13446.6 KEY66377.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein HMGL-like PF00682.19 KEY66377.1 - 0.16 11.5 0.6 0.29 10.6 0.6 1.3 1 0 0 1 1 1 0 HMGL-like DUF3176 PF11374.8 KEY66378.1 - 7.8e-16 58.2 1.1 7.8e-15 55.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Tmemb_14 PF03647.13 KEY66379.1 - 8.4e-20 71.3 4.9 9.6e-20 71.1 4.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C NADH_dh_m_C1 PF15088.6 KEY66379.1 - 0.11 12.2 0.0 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Gram_pos_anchor PF00746.21 KEY66379.1 - 7.8 6.5 11.1 13 5.8 0.0 3.9 4 0 0 4 4 4 0 LPXTG cell wall anchor motif AMP-binding PF00501.28 KEY66380.1 - 2.2e-94 316.5 0.0 3.6e-94 315.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KEY66380.1 - 1.1e-74 251.2 0.3 2.9e-74 249.8 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY66380.1 - 5.2e-56 190.5 0.1 8.6e-56 189.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY66380.1 - 1.2e-54 184.9 0.5 1.5e-53 181.4 0.3 2.5 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 KEY66380.1 - 2.1e-46 158.2 0.0 2.2e-44 151.5 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KEY66380.1 - 9.7e-45 151.4 0.4 3.1e-44 149.8 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEY66380.1 - 3e-25 88.3 0.2 2.6e-12 46.9 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KEY66380.1 - 4.8e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KEY66380.1 - 1.6e-08 34.3 0.0 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEY66380.1 - 9.2e-07 28.5 0.1 5.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KEY66380.1 - 1.1e-06 28.3 0.0 0.029 13.8 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 KEY66380.1 - 5e-06 27.4 0.0 1.3e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KEY66380.1 - 1e-05 24.8 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 KEY66380.1 - 1.7e-05 24.4 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 KEY66380.1 - 0.11 11.5 0.0 8 5.4 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEY66381.1 - 3.8e-19 69.2 0.0 5.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY66381.1 - 2.8e-08 33.9 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY66381.1 - 4.4e-05 23.5 0.0 7.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66381.1 - 0.0047 16.4 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KEY66381.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PhyH PF05721.13 KEY66382.1 - 2e-35 123.0 0.1 2.5e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 KEY66382.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.12 KEY66382.1 - 0.065 12.0 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NAD_binding_10 PF13460.6 KEY66384.1 - 3.1e-33 115.2 0.5 3.7e-33 115.0 0.5 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY66384.1 - 1.5e-05 24.6 0.0 3.2e-05 23.5 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY66384.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain HdeA PF06411.11 KEY66384.1 - 0.075 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Glyco_hydro_61 PF03443.14 KEY66385.1 - 5.9e-66 222.3 0.0 5.9e-66 222.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY66385.1 - 3.7e-12 46.0 7.4 1e-11 44.6 7.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Alpha-amylase PF00128.24 KEY66386.1 - 1.3e-23 84.1 4.3 3.2e-23 82.8 4.3 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KEY66386.1 - 1.7e-06 26.6 0.1 0.033 12.4 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KEY66386.1 - 0.00095 19.3 0.1 0.0054 16.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) DUF1996 PF09362.10 KEY66387.1 - 1.8e-33 116.5 0.1 1e-32 114.0 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_transf_8 PF01501.20 KEY66388.1 - 2.9e-08 33.6 0.3 8.5e-08 32.1 0.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_hydro_3_C PF01915.22 KEY66389.1 - 2.6e-56 190.8 0.0 6.2e-56 189.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY66389.1 - 6.9e-55 186.6 0.0 1.1e-54 186.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY66389.1 - 3.6e-18 65.4 0.2 1.3e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KEY66389.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.18 KEY66390.1 - 2.1e-22 79.4 0.1 3.1e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.14 KEY66390.1 - 1.2e-05 25.6 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FAA_hydrolase PF01557.18 KEY66391.1 - 1.7e-65 220.8 0.0 2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 KEY66392.1 - 3.3e-20 71.6 0.8 3.6e-17 61.8 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KEY66392.1 - 0.00096 18.8 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KEY66392.1 - 0.0012 18.5 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 KEY66392.1 - 0.0019 18.1 0.3 0.0041 17.0 0.1 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain Sugar_tr PF00083.24 KEY66393.1 - 1.3e-86 291.3 27.5 1.4e-86 291.1 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66393.1 - 1.8e-29 102.8 50.8 3.6e-24 85.3 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY66393.1 - 5.9e-06 25.0 1.5 5.9e-06 25.0 1.5 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7tm_1 PF00001.21 KEY66393.1 - 0.00053 19.4 0.4 0.00053 19.4 0.4 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GP41 PF00517.17 KEY66393.1 - 0.034 14.0 0.8 0.4 10.6 0.6 2.2 2 0 0 2 2 2 0 Retroviral envelope protein FAD_binding_3 PF01494.19 KEY66394.1 - 4.3e-59 200.5 0.0 6.1e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Gly_transf_sug PF04488.15 KEY66394.1 - 1.3e-05 25.8 0.0 3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4328 PF14219.6 KEY66395.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2207 PF09972.9 KEY66395.1 - 0.059 12.1 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KEY66395.1 - 0.094 12.1 2.1 0.16 11.4 2.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF5305 PF17231.2 KEY66395.1 - 0.14 11.5 0.6 2.4 7.5 0.6 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 KEY66395.1 - 0.17 11.7 1.9 0.35 10.7 1.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ketoacyl-synt PF00109.26 KEY66396.1 - 9e-73 245.0 0.0 2.3e-72 243.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY66396.1 - 4.8e-62 209.1 1.1 1.4e-61 207.5 1.1 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KEY66396.1 - 1.9e-51 175.5 0.0 3.3e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY66396.1 - 2.1e-48 165.1 0.0 3.5e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY66396.1 - 2.9e-38 130.5 0.4 2.7e-37 127.4 0.1 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY66396.1 - 2.2e-19 69.9 0.0 4.7e-18 65.7 0.0 2.9 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEY66396.1 - 8.1e-15 54.8 2.1 2.5e-14 53.2 0.3 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KEY66396.1 - 1.3e-11 44.6 0.1 4.7e-11 42.8 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KEY66396.1 - 3.3e-10 39.9 0.3 1e-09 38.3 0.3 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KEY66396.1 - 9.1e-07 30.0 0.0 2.8e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEY66396.1 - 1e-06 29.0 0.4 3.1e-06 27.4 0.4 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KEY66396.1 - 0.00029 20.7 0.0 0.00081 19.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 KEY66396.1 - 0.00053 19.2 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEY66396.1 - 0.0036 16.7 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 KEY66396.1 - 0.026 13.9 0.3 0.069 12.5 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain NmrA PF05368.13 KEY66396.1 - 0.065 12.8 1.5 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family FSH1 PF03959.13 KEY66397.1 - 6.5e-21 75.0 0.0 2e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ABC_membrane PF00664.23 KEY66398.1 - 2.7e-64 217.5 27.6 5e-43 147.7 10.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY66398.1 - 1.3e-63 213.6 0.0 1.8e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY66398.1 - 7.3e-16 58.3 2.4 0.00023 20.7 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY66398.1 - 1.2e-09 37.8 0.1 0.00059 19.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KEY66398.1 - 4.6e-09 35.6 0.5 0.032 13.1 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KEY66398.1 - 6.4e-09 36.4 0.7 0.0055 17.1 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY66398.1 - 2.2e-08 34.5 0.3 0.01 16.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KEY66398.1 - 1.4e-07 31.6 3.8 0.02 14.7 0.2 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY66398.1 - 2.5e-07 31.4 0.0 0.019 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY66398.1 - 6.1e-07 29.5 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KEY66398.1 - 1.8e-06 27.8 0.7 0.16 11.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KEY66398.1 - 2e-06 27.5 0.1 0.097 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KEY66398.1 - 2.5e-06 27.5 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KEY66398.1 - 1.8e-05 25.3 0.0 0.37 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEY66398.1 - 0.00015 22.1 0.0 0.54 10.6 0.0 3.4 3 2 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KEY66398.1 - 0.00017 21.3 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY66398.1 - 0.00032 20.9 0.1 0.75 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KEY66398.1 - 0.00033 20.6 0.0 0.5 10.3 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 KEY66398.1 - 0.00062 20.2 2.8 3.8 7.9 0.2 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEY66398.1 - 0.0008 19.7 0.2 1.1 9.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEY66398.1 - 0.001 18.6 0.1 0.93 9.0 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region SRP54 PF00448.22 KEY66398.1 - 0.0015 18.2 0.4 1.4 8.5 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KEY66398.1 - 0.0017 17.6 0.4 2.7 7.1 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain ATP_bind_1 PF03029.17 KEY66398.1 - 0.0029 17.4 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KEY66398.1 - 0.004 16.9 2.0 17 5.1 0.0 4.7 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_5 PF07728.14 KEY66398.1 - 0.0047 16.9 0.0 6.2 6.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KEY66398.1 - 0.0062 16.8 1.3 4.3 7.7 0.2 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KEY66398.1 - 0.014 15.3 0.1 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.29 KEY66398.1 - 0.017 14.9 0.1 16 5.2 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase Cytidylate_kin PF02224.18 KEY66398.1 - 0.021 14.6 0.5 2.2 7.9 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase ATPase PF06745.13 KEY66398.1 - 0.034 13.5 1.1 0.66 9.3 0.0 2.8 3 0 0 3 3 3 0 KaiC APS_kinase PF01583.20 KEY66398.1 - 0.036 14.0 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KEY66398.1 - 0.039 14.0 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KEY66398.1 - 0.041 14.3 0.1 14 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEY66398.1 - 0.059 13.0 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KEY66398.1 - 0.07 12.3 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 KEY66398.1 - 0.072 13.5 0.0 23 5.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KEY66398.1 - 0.079 13.0 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KEY66398.1 - 0.084 12.8 1.7 58 3.5 0.0 4.1 4 0 0 4 4 4 0 NTPase PRK PF00485.18 KEY66398.1 - 0.1 12.3 0.2 16 5.1 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.6 KEY66398.1 - 0.11 11.5 0.0 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_14 PF13173.6 KEY66398.1 - 0.11 12.5 0.0 33 4.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 KEY66398.1 - 0.13 11.5 0.5 20 4.4 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin DJ-1_PfpI PF01965.24 KEY66399.1 - 6.3e-10 39.1 0.0 2.4e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KEY66399.1 - 0.0074 16.0 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like Hva1_TUDOR PF11160.8 KEY66400.1 - 1.3e-08 34.9 0.2 1.8e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Molydop_binding PF01568.21 KEY66400.1 - 0.0028 17.7 0.2 0.006 16.6 0.1 1.6 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain Glyco_hydro_61 PF03443.14 KEY66401.1 - 3e-52 177.5 0.1 3.5e-52 177.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_10 PF13673.7 KEY66402.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY66402.1 - 0.00018 21.8 0.0 0.0003 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY66402.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEY66402.1 - 0.077 13.0 0.2 0.2 11.6 0.2 1.6 1 1 0 1 1 1 0 FR47-like protein adh_short PF00106.25 KEY66404.1 - 2.7e-34 118.3 0.2 3.5e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66404.1 - 1.5e-26 93.4 0.1 9.3e-26 90.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66404.1 - 2.1e-05 24.5 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY66404.1 - 0.097 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.23 KEY66405.1 - 1e-20 73.9 0.4 2e-20 72.9 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66405.1 - 1.2e-10 41.3 0.5 2.4e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.19 KEY66407.1 - 6.1e-60 203.1 0.1 8.5e-60 202.6 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY66407.1 - 1.7e-30 106.4 0.0 2.6e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY66407.1 - 4.4e-07 29.3 1.0 0.016 14.3 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEY66407.1 - 4.4e-06 26.0 0.6 7.5e-06 25.2 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY66407.1 - 8.5e-05 22.3 0.3 0.0068 16.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY66407.1 - 0.0045 16.3 0.1 0.0077 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEY66407.1 - 0.0068 16.6 0.2 0.083 13.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEY66407.1 - 0.021 13.7 0.1 0.038 12.8 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 KEY66407.1 - 0.072 12.4 0.2 12 5.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.14 KEY66407.1 - 0.089 11.5 0.6 0.22 10.2 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KEY66407.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KEY66407.1 - 0.13 11.5 0.7 0.23 10.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KEY66408.1 - 1.2e-55 189.0 0.0 1.6e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY66408.1 - 8.7e-34 117.1 0.1 1.4e-33 116.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY66408.1 - 5.4e-06 25.7 0.0 3.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEY66408.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY66408.1 - 0.00023 20.9 0.2 0.0012 18.5 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY66408.1 - 0.00024 21.3 0.3 0.00077 19.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY66408.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY66408.1 - 0.0047 16.2 0.1 0.0096 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEY66408.1 - 0.0097 15.2 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY66408.1 - 0.061 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KEY66408.1 - 0.089 12.8 0.4 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KEY66408.1 - 0.22 10.4 0.1 0.3 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.26 KEY66409.1 - 1.9e-08 34.4 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY66409.1 - 0.00016 21.5 0.0 0.00044 20.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KEY66410.1 - 2.6e-71 240.2 0.0 1.1e-70 238.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY66410.1 - 3.2e-50 170.6 0.1 6.3e-49 166.3 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KEY66410.1 - 4.7e-44 150.8 0.0 8.1e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY66410.1 - 8.4e-42 143.8 0.0 1.6e-41 142.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KEY66410.1 - 8.5e-34 116.9 0.0 4.2e-33 114.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KEY66410.1 - 1.3e-27 96.2 0.0 3.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEY66410.1 - 7.6e-18 65.1 0.0 1.8e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY66410.1 - 3.2e-15 56.6 0.0 8.4e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KEY66410.1 - 1.2e-13 51.0 0.0 9.2e-12 44.9 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KEY66410.1 - 1.2e-12 48.4 0.0 6.6e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.19 KEY66410.1 - 2.2e-11 43.3 0.0 1.6e-08 33.9 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEY66410.1 - 4.9e-10 39.2 0.0 1.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KEY66410.1 - 1.2e-09 38.3 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66410.1 - 1.7e-09 38.2 0.0 1.1e-08 35.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66410.1 - 5.2e-08 32.8 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEY66410.1 - 3e-06 27.5 0.0 9.3e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEY66410.1 - 0.0015 18.0 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KEY66410.1 - 0.0018 17.7 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RmlD_sub_bind PF04321.17 KEY66410.1 - 0.0064 15.6 0.0 0.03 13.4 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 KEY66410.1 - 0.017 15.5 0.0 0.082 13.4 0.0 2.2 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_16 PF10294.9 KEY66410.1 - 0.021 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DREV PF05219.12 KEY66410.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 KEY66410.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Alpha_L_fucos PF01120.17 KEY66411.1 - 4.3e-94 315.8 2.9 5.7e-94 315.4 2.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KEY66411.1 - 3.6e-10 40.3 0.0 8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Mif2_N PF15624.6 KEY66412.1 - 2.3e-33 115.8 4.1 2.3e-33 115.8 4.1 2.9 1 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RNase_HII PF01351.18 KEY66413.1 - 1.2e-46 159.1 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 KEY66414.1 - 0 1054.2 0.0 0 1053.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KEY66414.1 - 1e-07 31.5 0.1 1.7e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KEY66414.1 - 2.2e-06 27.9 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KEY66414.1 - 0.00011 22.3 0.0 0.00028 20.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KEY66414.1 - 0.00086 19.6 0.0 0.0033 17.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KEY66414.1 - 0.04 13.2 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Septin AstE_AspA PF04952.14 KEY66414.1 - 0.079 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DLH PF01738.18 KEY66415.1 - 4.5e-23 81.9 0.0 6.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Cadherin_5 PF17892.1 KEY66415.1 - 0.013 15.4 0.2 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Cadherin-like domain Peptidase_S15 PF02129.18 KEY66415.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) MS_channel PF00924.18 KEY66416.1 - 1.4e-16 60.7 0.9 2.4e-16 59.9 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KEY66416.1 - 0.038 13.5 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KEY66416.1 - 0.039 13.5 0.1 0.086 12.4 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KEY66416.1 - 0.052 13.5 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Sugar_tr PF00083.24 KEY66417.1 - 7.8e-90 301.9 21.4 9e-90 301.7 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66417.1 - 8.2e-14 51.3 47.8 7.6e-09 34.9 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abp2 PF09441.10 KEY66418.1 - 6.2e-77 257.5 0.0 9.1e-77 256.9 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Sds3 PF08598.11 KEY66420.1 - 9e-27 94.5 3.3 1.3e-26 94.0 3.3 1.3 1 0 0 1 1 1 1 Sds3-like COG5 PF10392.9 KEY66421.1 - 0.037 14.2 6.6 0.051 13.7 1.9 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 GerD PF17898.1 KEY66421.1 - 0.17 11.9 4.4 0.35 10.8 0.6 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF3486 PF11985.8 KEY66421.1 - 0.17 12.3 5.9 0.26 11.7 3.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3486) DUF812 PF05667.11 KEY66421.1 - 0.25 10.2 9.2 0.69 8.7 9.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF883 PF05957.13 KEY66421.1 - 0.6 10.8 9.8 1.1 9.9 0.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) CHASE3 PF05227.13 KEY66421.1 - 2 8.3 8.6 0.62 10.0 1.5 2.4 2 1 1 3 3 3 0 CHASE3 domain DUF4142 PF13628.6 KEY66421.1 - 2.1 8.6 6.4 2.8 8.2 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4142) YtxH PF12732.7 KEY66421.1 - 2.8 8.5 5.0 14 6.3 2.6 3.1 2 2 0 2 2 2 0 YtxH-like protein Laminin_II PF06009.12 KEY66421.1 - 3.1 7.8 8.9 2 8.4 3.7 2.3 2 0 0 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 KEY66421.1 - 4.4 7.9 6.2 1.3 9.6 1.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Ala_racemase_N PF01168.20 KEY66422.1 - 2.6e-21 76.3 0.0 3.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Herpes_UL3 PF03369.13 KEY66422.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein Adaptin_N PF01602.20 KEY66423.1 - 1.4e-122 410.0 9.2 1.7e-122 409.7 9.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KEY66423.1 - 1.9e-45 153.7 0.0 4.9e-45 152.4 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KEY66423.1 - 5.3e-13 49.2 0.0 9.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain AP4E_app_platf PF14807.6 KEY66423.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF4259 PF14078.6 KEY66423.1 - 0.03 15.1 0.3 0.27 12.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4259) RTP1_C1 PF10363.9 KEY66423.1 - 0.055 13.7 0.1 0.24 11.6 0.1 2.1 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Methyltransf_11 PF08241.12 KEY66424.1 - 1.2e-10 41.9 0.0 3.6e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66424.1 - 3.2e-10 40.6 0.0 5.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY66424.1 - 1.3e-08 34.9 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66424.1 - 6.9e-08 33.1 0.0 1.9e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66424.1 - 8.2e-06 25.7 0.0 2.5e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY66424.1 - 0.008 15.5 0.0 0.023 14.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 KEY66425.1 - 2.3e-30 106.0 0.0 3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AFT PF08731.11 KEY66427.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT Kunitz_legume PF00197.18 KEY66427.1 - 0.038 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Trypsin and protease inhibitor CN_hydrolase PF00795.22 KEY66429.1 - 5e-36 124.4 0.0 1.1e-35 123.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 KEY66429.1 - 3.5e-29 102.4 2.4 3.2e-24 86.1 2.3 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KEY66430.1 - 7.3e-88 293.7 0.0 1e-87 293.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KEY66430.1 - 1.2e-29 102.8 0.0 7e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KEY66430.1 - 2.3e-18 66.3 0.0 3.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KEY66430.1 - 3.3e-18 66.4 0.6 6.6e-18 65.4 0.6 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KEY66430.1 - 4.7e-12 45.7 0.1 9.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KEY66430.1 - 1.9e-05 24.3 0.6 4.9e-05 22.9 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEY66430.1 - 5.3e-05 23.2 0.2 0.00012 22.0 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KEY66430.1 - 0.24 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family V_ATPase_I PF01496.19 KEY66431.1 - 0 1048.6 0.0 0 1048.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 KEY66431.1 - 0.015 14.9 7.6 0.16 11.5 1.1 2.3 2 0 0 2 2 2 0 Intermediate filament protein EzrA PF06160.12 KEY66431.1 - 0.018 13.3 10.4 0.28 9.3 1.8 2.4 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA SesA PF17107.5 KEY66431.1 - 0.019 15.2 0.3 0.47 10.7 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF639 PF04842.12 KEY66431.1 - 0.085 12.3 2.5 0.21 11.0 0.4 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Golgin_A5 PF09787.9 KEY66431.1 - 0.17 11.3 7.7 0.74 9.2 1.4 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3552 PF12072.8 KEY66431.1 - 0.22 10.9 2.7 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KEY66431.1 - 0.31 9.9 4.6 4.9 6.0 0.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CheZ PF04344.13 KEY66431.1 - 0.33 10.8 3.4 1.9 8.3 0.2 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Baculo_PEP_C PF04513.12 KEY66431.1 - 0.43 10.6 6.3 0.61 10.1 1.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KEY66431.1 - 0.46 10.5 5.3 4.4 7.4 0.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KEY66431.1 - 0.47 9.9 4.7 10 5.5 1.8 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FAM184 PF15665.5 KEY66431.1 - 0.67 9.7 6.4 0.21 11.3 0.9 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DASH_Dad2 PF08654.10 KEY66431.1 - 0.74 10.3 3.5 12 6.4 1.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 LXG PF04740.12 KEY66431.1 - 0.87 9.3 5.6 0.34 10.6 1.2 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4140 PF13600.6 KEY66431.1 - 1.1 9.7 4.3 3.6 8.1 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KEY66431.1 - 1.2 9.0 8.4 0.44 10.3 0.8 3.3 3 0 0 3 3 3 0 Septum formation initiator UPF0449 PF15136.6 KEY66431.1 - 2.6 8.6 7.0 1.8 9.1 0.4 2.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 SKA2 PF16740.5 KEY66431.1 - 3.6 7.4 6.3 29 4.5 0.5 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Prefoldin_2 PF01920.20 KEY66431.1 - 4.1 7.4 5.5 37 4.3 0.2 2.9 3 0 0 3 3 3 0 Prefoldin subunit Laminin_II PF06009.12 KEY66431.1 - 4.5 7.3 6.6 26 4.8 2.8 2.5 2 0 0 2 2 2 0 Laminin Domain II LRR_6 PF13516.6 KEY66432.1 - 0.00039 20.2 0.0 0.96 9.7 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.7 KEY66432.1 - 0.0072 16.2 0.4 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like ING PF12998.7 KEY66433.1 - 9.1e-07 29.4 1.8 0.0022 18.6 0.0 2.6 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KEY66433.1 - 1.4e-06 28.1 7.1 2.3e-06 27.4 7.1 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KEY66433.1 - 0.51 10.6 2.4 1.1 9.6 2.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prenyltransf PF01255.19 KEY66434.1 - 2.6e-80 269.2 0.0 4.5e-80 268.4 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 KEY66434.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_63 PF03200.16 KEY66435.1 - 1.9e-09 36.8 8.8 2.8e-07 29.7 0.1 4.1 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain 1-cysPrx_C PF10417.9 KEY66435.1 - 0.16 11.9 1.2 0.43 10.5 1.2 1.7 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Hep_59 PF07052.11 KEY66435.1 - 0.16 12.7 0.6 0.4 11.5 0.6 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 OSCP PF00213.18 KEY66436.1 - 6.5e-48 163.1 0.6 7.6e-48 162.9 0.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit HTH_IclR PF09339.10 KEY66436.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Mob1_phocein PF03637.17 KEY66437.1 - 5.6e-70 234.7 0.0 7.6e-70 234.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DBR1 PF05011.13 KEY66438.1 - 2e-45 154.6 0.0 5.5e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KEY66438.1 - 5.3e-05 23.8 1.1 5.3e-05 23.8 1.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.15 KEY66439.1 - 2.3e-06 27.7 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain OAS1_C PF10421.9 KEY66439.1 - 0.16 11.4 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Ras PF00071.22 KEY66440.1 - 1.4e-47 161.3 0.0 2e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY66440.1 - 3.5e-20 72.4 0.0 7.4e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY66440.1 - 2.1e-05 24.0 0.0 6.8e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family AAA_7 PF12775.7 KEY66440.1 - 0.045 13.3 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 KEY66441.1 - 5e-23 81.0 4.7 6.7e-15 55.0 0.5 2.1 2 0 0 2 2 2 2 DASH complex subunit Dad1 PilJ PF13675.6 KEY66441.1 - 0.015 15.3 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glutaredoxin2_C PF04399.13 KEY66441.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Peptidase_M7 PF02031.16 KEY66441.1 - 0.17 12.0 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Myb_DNA-binding PF00249.31 KEY66442.1 - 2.8e-10 40.2 0.4 0.00012 22.1 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DS PF01916.17 KEY66443.1 - 1.6e-130 434.6 0.0 1.8e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Aldo_ket_red PF00248.21 KEY66444.1 - 1.7e-16 60.3 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 KEY66445.1 - 5.7e-17 62.7 0.1 1.1e-16 61.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_11 PF08241.12 KEY66446.1 - 6.4e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66446.1 - 1.4e-10 41.7 0.0 2.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY66446.1 - 1.2e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66446.1 - 6.6e-06 26.8 0.0 1.4e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66446.1 - 0.00071 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.31 KEY66447.1 - 2.5e-13 50.0 2.2 7.5e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY66447.1 - 6.3e-05 23.1 2.7 0.0076 16.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.25 KEY66448.1 - 2.6e-22 78.6 1.3 4e-22 78.0 1.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KEY66448.1 - 2.2e-20 72.9 0.0 3.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KEY66448.1 - 0.0007 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MacB_PCD PF12704.7 KEY66448.1 - 0.021 15.2 0.0 0.038 14.3 0.0 1.5 1 1 0 1 1 1 0 MacB-like periplasmic core domain T6_Ig_like PF18002.1 KEY66448.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 T6 antigen Ig like domain zf-RING_2 PF13639.6 KEY66449.1 - 2.2e-12 47.1 4.9 3.9e-12 46.3 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEY66449.1 - 8.7e-11 41.4 1.8 1.8e-10 40.4 1.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY66449.1 - 1.3e-07 31.4 4.2 2.2e-07 30.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY66449.1 - 8.9e-07 28.7 3.5 1.6e-06 27.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEY66449.1 - 1.6e-06 28.3 5.0 4.3e-06 26.9 5.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEY66449.1 - 9e-06 25.6 2.1 1.8e-05 24.6 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEY66449.1 - 1.5e-05 24.7 3.7 2.9e-05 23.8 3.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEY66449.1 - 0.00084 19.3 2.1 0.00084 19.3 2.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEY66449.1 - 0.0013 18.7 0.8 0.0028 17.7 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KEY66449.1 - 0.0017 18.2 2.6 0.0035 17.2 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KEY66449.1 - 0.084 12.7 3.1 0.16 11.8 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KEY66449.1 - 2.1 8.3 3.8 9.1 6.3 2.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 KEY66449.1 - 2.4 8.5 4.8 2 8.8 2.4 2.0 2 0 0 2 2 2 0 RING-like domain Glyco_hydro_cc PF11790.8 KEY66450.1 - 2.4e-55 187.7 0.2 3.4e-55 187.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.18 KEY66451.1 - 3.3e-08 33.5 9.3 5.4e-08 32.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY66451.1 - 1.1e-05 24.4 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LtrA PF06772.11 KEY66453.1 - 1.3e-36 126.5 20.5 4.1e-34 118.4 20.5 2.1 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) NEMO PF11577.8 KEY66453.1 - 0.18 11.9 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO ATP-synt_Eps PF04627.13 KEY66454.1 - 6.2e-25 86.9 3.4 9.3e-25 86.4 3.4 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 KEY66455.1 - 6.4e-63 211.2 0.0 2e-62 209.6 0.0 1.9 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.27 KEY66456.1 - 1.5e-51 172.3 4.4 1.6e-16 60.0 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY66456.1 - 0.056 12.6 1.0 1.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RPN6_N PF18055.1 KEY66458.1 - 1.7e-41 141.2 2.7 1.7e-41 141.2 2.7 2.6 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KEY66458.1 - 2.6e-20 72.9 0.2 1.4e-19 70.5 0.2 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KEY66458.1 - 1.8e-09 37.2 1.0 1.8e-09 37.2 1.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KEY66458.1 - 0.00012 21.7 0.2 0.00031 20.4 0.2 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.6 KEY66458.1 - 0.00038 20.7 16.2 0.088 13.1 1.9 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY66458.1 - 0.0017 18.4 1.9 21 5.7 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY66458.1 - 0.0021 18.0 5.9 0.56 10.4 0.4 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY66458.1 - 0.0041 16.5 2.4 0.0041 16.5 2.4 2.7 2 2 1 3 3 3 1 MalT-like TPR region TPR_1 PF00515.28 KEY66458.1 - 0.033 14.0 0.3 32 4.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY66458.1 - 0.043 14.7 11.1 12 7.1 0.2 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF87 PF01935.17 KEY66458.1 - 0.049 13.7 2.2 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TPR_2 PF07719.17 KEY66458.1 - 0.063 13.4 5.6 9.4 6.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DprA_WH PF17782.1 KEY66458.1 - 0.097 12.8 0.1 0.8 9.9 0.0 2.5 3 0 0 3 3 2 0 DprA winged helix domain TPR_4 PF07721.14 KEY66458.1 - 0.1 13.3 1.9 0.58 10.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY66458.1 - 0.52 10.2 6.5 77 3.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KEY66459.1 - 5.7e-62 210.2 0.0 7.3e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SPC25 PF06703.11 KEY66459.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-CCCH PF00642.24 KEY66460.1 - 2.6e-20 71.8 34.2 2e-07 30.8 0.7 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEY66460.1 - 2.2e-17 62.5 34.3 2.1e-05 24.4 2.8 5.4 5 0 0 5 5 5 5 Zinc finger domain Methyltransf_23 PF13489.6 KEY66460.1 - 1.2e-10 41.5 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Torus PF16131.5 KEY66460.1 - 3.7e-08 34.0 24.9 0.0028 18.3 0.5 5.5 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KEY66460.1 - 8.3e-08 31.9 36.8 0.00094 18.9 0.9 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger Methyltransf_12 PF08242.12 KEY66460.1 - 0.00022 21.9 0.0 0.00072 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66460.1 - 0.0054 17.3 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66460.1 - 0.015 16.0 0.0 0.04 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF1776 PF08643.10 KEY66461.1 - 3e-102 342.0 0.0 3.7e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HET PF06985.11 KEY66462.1 - 4.1e-23 82.3 0.1 4.3e-22 79.0 0.1 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulf_transp PF04143.14 KEY66463.1 - 1.4e-38 133.3 27.3 1.4e-38 133.3 27.3 1.3 1 1 0 1 1 1 1 Sulphur transport Pkinase PF00069.25 KEY66464.1 - 1.3e-08 34.5 0.0 1.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66464.1 - 0.16 11.3 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase HMGL-like PF00682.19 KEY66467.1 - 6.5e-79 265.2 0.0 2.5e-78 263.3 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KEY66467.1 - 3.1e-25 88.6 0.0 1.1e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain Aminotran_5 PF00266.19 KEY66469.1 - 1.3e-31 109.9 0.0 1.6e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Bac_luciferase PF00296.20 KEY66470.1 - 4.5e-58 197.1 1.8 6.5e-58 196.6 1.8 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF3435 PF11917.8 KEY66470.1 - 3.3e-14 52.7 0.2 1.3e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) p450 PF00067.22 KEY66471.1 - 1.6e-47 162.3 0.0 2e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 KEY66472.1 - 3.2e-61 207.5 0.0 4.5e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KEY66472.1 - 1.8e-22 79.7 0.1 2.9e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66472.1 - 1.8e-05 24.7 16.5 1.8e-05 24.7 16.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KEY66473.1 - 4.1e-11 42.7 0.0 5e-10 39.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY66473.1 - 5.1e-08 33.0 0.6 8.8e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.7 KEY66474.1 - 1.7e-12 48.4 0.0 2.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY66474.1 - 2e-10 40.8 0.2 1.1e-09 38.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY66474.1 - 4.7e-08 32.6 0.0 6.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF4993 PF16384.5 KEY66474.1 - 0.14 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Bac_luciferase PF00296.20 KEY66475.1 - 7.2e-55 186.6 1.0 9.9e-55 186.2 1.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Aa_trans PF01490.18 KEY66476.1 - 1.9e-21 76.3 33.1 8.2e-21 74.2 33.1 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein EGF_2 PF07974.13 KEY66478.1 - 1.1e-05 25.7 1.7 3.1e-05 24.3 1.7 1.8 1 1 0 1 1 1 1 EGF-like domain EB PF01683.18 KEY66478.1 - 0.01 16.1 2.9 0.019 15.3 2.9 1.4 1 0 0 1 1 1 0 EB module Glyco_hydro_43 PF04616.14 KEY66478.1 - 0.011 15.1 0.7 0.08 12.2 0.7 2.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 43 CBM64 PF18666.1 KEY66478.1 - 0.072 13.2 1.8 0.14 12.2 1.8 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 64 Squash PF00299.18 KEY66478.1 - 1.5 8.9 6.6 0.55 10.3 2.7 2.1 2 0 0 2 2 2 0 Squash family serine protease inhibitor Aminotran_1_2 PF00155.21 KEY66479.1 - 2.6e-37 128.9 0.0 3.8e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S9 PF00326.21 KEY66479.1 - 3e-15 56.3 0.0 5.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEY66479.1 - 6.2e-05 23.0 0.4 0.00039 20.4 0.1 2.4 2 2 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KEY66479.1 - 0.0001 22.0 0.0 0.0004 20.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEY66479.1 - 0.098 12.3 0.1 3.4 7.2 0.1 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY66479.1 - 0.17 11.1 0.0 4.8 6.4 0.0 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 HET PF06985.11 KEY66480.1 - 2.7e-34 118.6 1.0 5.2e-34 117.7 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C_GCAxxG_C_C PF09719.10 KEY66480.1 - 0.044 14.1 0.3 0.083 13.2 0.3 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Ribosomal_L27A PF00828.19 KEY66480.1 - 0.12 13.1 0.2 0.21 12.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HATPase_c PF02518.26 KEY66481.1 - 4.3e-29 101.3 0.2 9.4e-29 100.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY66481.1 - 2.2e-22 79.3 0.1 5.2e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY66481.1 - 9.6e-22 76.8 0.0 3e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KEY66481.1 - 1.5e-16 60.5 0.1 4.1e-16 59.1 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEY66481.1 - 7.1e-11 42.3 0.0 0.00028 21.1 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 KEY66481.1 - 2.5e-08 34.1 0.7 0.0031 17.7 0.0 5.0 4 2 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KEY66481.1 - 0.00021 21.2 0.0 0.55 10.3 0.0 4.0 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 KEY66481.1 - 0.00041 20.3 0.0 1.4 8.9 0.0 4.2 4 0 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.6 KEY66481.1 - 0.072 12.9 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KEY66484.1 - 1.1e-61 208.3 0.0 1.8e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KEY66484.1 - 0.0019 17.5 19.3 0.013 14.8 2.5 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others Peptidase_M54 PF07998.11 KEY66484.1 - 0.21 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 zf-Sec23_Sec24 PF04810.15 KEY66484.1 - 0.44 10.7 11.4 3.8 7.6 0.0 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.7 KEY66484.1 - 0.83 9.7 12.6 10 6.2 12.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KEY66484.1 - 0.88 10.4 6.5 5.3 7.9 6.9 1.9 1 1 1 2 2 2 0 zinc-ribbon family C1_2 PF03107.16 KEY66484.1 - 1.2 9.5 8.3 0.51 10.7 0.4 2.5 2 0 0 2 2 2 0 C1 domain DUF45 PF01863.17 KEY66484.1 - 2.1 8.4 6.4 0.36 10.9 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-ribbon_3 PF13248.6 KEY66484.1 - 4.1 6.9 7.7 0.51 9.8 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 KEY66484.1 - 7.6 6.6 7.5 6.2 6.9 0.9 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Methyltransf_25 PF13649.6 KEY66485.1 - 2.3e-16 60.2 0.1 3.6e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66485.1 - 5.9e-14 52.1 0.0 7.8e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66485.1 - 5.4e-12 46.2 0.2 3.1e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66485.1 - 1.2e-11 45.2 0.0 2.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY66485.1 - 1.6e-08 34.6 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY66485.1 - 5.8e-07 29.2 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KEY66485.1 - 8.5e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEY66485.1 - 0.00041 19.5 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KEY66485.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEY66485.1 - 0.0049 16.3 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KEY66485.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEY66485.1 - 0.034 13.4 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KEY66485.1 - 0.07 12.0 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_5 PF01795.19 KEY66485.1 - 0.23 10.9 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Amidase PF01425.21 KEY66486.1 - 2.9e-90 303.4 0.0 3.8e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 Amidase MCD_N PF17408.2 KEY66487.1 - 0.19 11.9 0.4 0.92 9.7 0.2 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain NAD_binding_6 PF08030.12 KEY66488.1 - 4.2e-22 78.9 0.0 6.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY66488.1 - 5.5e-22 77.9 0.0 1.2e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KEY66488.1 - 8.9e-21 74.3 9.4 8.9e-21 74.3 9.4 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEY66488.1 - 0.07 13.8 0.0 8.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEY66488.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain LrgA PF03788.14 KEY66488.1 - 0.18 11.8 1.0 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 LrgA family C2 PF00168.30 KEY66489.1 - 3.1e-21 75.6 0.0 3.1e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain Hydin_ADK PF17213.3 KEY66489.1 - 0.63 10.3 2.6 7.8 6.7 0.1 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Sacchrp_dh_NADP PF03435.18 KEY66490.1 - 4.1e-16 59.4 0.1 8.8e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY66490.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEY66490.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HHV-1_VABD PF16852.5 KEY66491.1 - 2 8.5 5.4 3.4 7.7 0.3 2.7 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain DUF1713 PF08213.11 KEY66492.1 - 1.4e-09 37.7 21.7 1.4e-09 37.7 21.7 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KEY66492.1 - 0.018 15.7 0.0 0.042 14.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.6 KEY66493.1 - 3.8e-98 327.4 0.0 7.4e-98 326.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KEY66493.1 - 9.6e-90 300.4 0.0 1.7e-89 299.6 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KEY66493.1 - 1.7e-64 216.9 0.0 1.2e-63 214.2 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KEY66493.1 - 6.3e-33 112.6 0.0 1.9e-32 111.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KEY66493.1 - 0.00043 20.6 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY66493.1 - 0.0014 18.4 1.5 0.015 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain Acetyltransf_1 PF00583.25 KEY66493.1 - 0.038 14.2 0.0 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MR_MLE_C PF13378.6 KEY66494.1 - 4.9e-55 186.5 0.1 6.7e-55 186.0 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEY66494.1 - 1.4e-14 54.3 0.0 2.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KEY66494.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.5 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus ADH_N PF08240.12 KEY66495.1 - 4e-27 94.3 1.1 6.2e-27 93.6 0.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY66495.1 - 2.3e-12 47.0 0.9 3e-12 46.6 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY66495.1 - 2.4e-09 37.0 1.9 6.4e-07 29.1 1.9 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KEY66495.1 - 0.0015 18.6 0.6 0.0063 16.6 0.1 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KEY66495.1 - 0.007 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 KEY66495.1 - 0.033 13.9 0.5 0.092 12.4 0.4 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 KEY66495.1 - 0.036 15.1 0.0 0.085 13.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KEY66495.1 - 0.2 11.9 0.7 0.78 10.0 0.4 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 KEY66495.1 - 0.22 11.0 0.0 0.61 9.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Dak1 PF02733.17 KEY66496.1 - 4.6e-104 347.6 2.8 4.6e-104 347.6 2.8 1.7 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KEY66496.1 - 6.9e-42 143.3 0.3 1.5e-41 142.2 0.3 1.6 1 0 0 1 1 1 1 DAK2 domain DUF3716 PF12511.8 KEY66497.1 - 3e-09 36.8 2.7 4.6e-09 36.2 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Ribosomal_60s PF00428.19 KEY66498.1 - 2.2 8.9 7.5 0.43 11.2 3.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4448 PF14610.6 KEY66499.1 - 1.3e-30 106.6 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.8 KEY66499.1 - 0.3 10.8 3.1 2.5 7.9 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) JmjC PF02373.22 KEY66500.1 - 7.1e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase UDPGT PF00201.18 KEY66501.1 - 4.9e-22 78.4 0.0 6.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEY66501.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain GIT_SHD PF08518.11 KEY66502.1 - 3.4e-23 80.9 5.4 9.5e-14 50.7 1.3 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT THP2 PF09432.10 KEY66502.1 - 0.0071 16.4 3.0 0.0071 16.4 3.0 2.4 1 1 1 2 2 2 1 Tho complex subunit THP2 PSII_Pbs27 PF13326.6 KEY66502.1 - 0.019 15.3 6.4 0.24 11.7 1.5 3.2 3 0 0 3 3 3 0 Photosystem II Pbs27 DUF2935 PF11155.8 KEY66502.1 - 2.1 8.7 6.0 35 4.7 4.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Macoilin PF09726.9 KEY66502.1 - 2.4 6.6 24.6 4.4 5.8 24.6 1.4 1 0 0 1 1 1 0 Macoilin family Syntaxin_2 PF14523.6 KEY66502.1 - 3.8 7.9 26.2 1.1 9.6 5.9 4.6 3 1 1 4 4 4 0 Syntaxin-like protein DUF3138 PF11336.8 KEY66502.1 - 7.1 5.1 8.0 12 4.3 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PRKG1_interact PF15898.5 KEY66502.1 - 9.1 7.2 40.2 1.2 10.1 10.8 3.9 2 1 3 5 5 5 0 cGMP-dependent protein kinase interacting domain Ssu72 PF04722.13 KEY66503.1 - 1.5e-85 285.6 0.0 1.7e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 KEY66504.1 - 1.6e-09 37.2 0.1 2.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY66504.1 - 9.2e-08 31.8 0.2 2.1e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY66504.1 - 0.00017 21.2 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain NAD_binding_1 PF00175.21 KEY66507.1 - 5.7e-31 107.4 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEY66507.1 - 3e-23 82.0 0.0 5.7e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEY66507.1 - 3.9e-09 36.8 0.0 0.00024 21.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KEY66507.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF2281 PF10047.9 KEY66507.1 - 0.062 14.0 2.1 2.7 8.8 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2281) TFR_dimer PF04253.15 KEY66508.1 - 1.7e-22 79.7 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEY66508.1 - 2.2e-19 69.9 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY66508.1 - 1.9e-09 37.4 0.9 6.5e-09 35.7 0.1 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KEY66508.1 - 0.0087 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin MFS_1 PF07690.16 KEY66509.1 - 5.6e-38 130.8 32.8 5.5e-28 97.9 7.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66509.1 - 2.5e-10 39.8 5.0 2.5e-10 39.8 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter SprT-like PF10263.9 KEY66510.1 - 3.1e-15 56.0 0.0 7.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 SprT-like family Epimerase PF01370.21 KEY66512.1 - 1e-09 38.2 0.0 0.00021 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY66512.1 - 3.3e-07 30.4 0.1 9.2e-07 28.9 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding DUF4859 PF16151.5 KEY66512.1 - 0.026 14.4 0.2 0.063 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Shikimate_DH PF01488.20 KEY66512.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KEY66512.1 - 0.039 14.4 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEY66512.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TFIIS_M PF07500.14 KEY66514.1 - 1.3e-26 93.3 0.4 1.3e-26 93.3 0.4 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KEY66514.1 - 3.4e-18 65.2 8.3 5.7e-18 64.5 8.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KEY66514.1 - 1.8e-10 40.7 1.8 3.5e-10 39.7 0.8 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain YkyA PF10368.9 KEY66514.1 - 1.6 8.4 10.5 0.19 11.4 3.8 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DNA_pol_delta_4 PF04081.13 KEY66514.1 - 2.7 8.4 7.4 6.9 7.0 0.3 2.4 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 PALP PF00291.25 KEY66515.1 - 1e-60 205.7 0.7 1.3e-60 205.3 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2685 PF10886.8 KEY66515.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Methyltransf_28 PF02636.17 KEY66516.1 - 3.1e-39 135.2 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KEY66516.1 - 0.00035 20.5 0.0 0.00086 19.2 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.19 KEY66517.1 - 5.3e-213 708.5 0.0 7.3e-213 708.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KEY66517.1 - 1.9e-16 59.9 0.2 1.9e-16 59.9 0.2 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KEY66517.1 - 4.8e-11 43.2 1.5 1.5e-10 41.6 1.5 1.9 1 0 0 1 1 1 1 DHHA1 domain DKNYY PF13644.6 KEY66517.1 - 0.072 13.9 1.6 0.29 11.9 0.3 2.5 2 1 0 2 2 2 0 DKNYY family DUF413 PF04219.12 KEY66517.1 - 0.073 13.1 1.8 8.8 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF Snapin_Pallidin PF14712.6 KEY66517.1 - 0.15 12.5 0.7 0.34 11.4 0.1 1.9 2 0 0 2 2 2 0 Snapin/Pallidin RCR PF12273.8 KEY66519.1 - 1.9e-12 47.9 4.1 2.8e-12 47.4 4.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Sel1 PF08238.12 KEY66520.1 - 1e-37 127.7 44.9 0.00015 22.3 0.1 14.0 13 1 0 13 13 13 9 Sel1 repeat TPR_7 PF13176.6 KEY66520.1 - 0.0015 18.4 5.4 4.5 7.5 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY66520.1 - 0.83 10.2 10.4 41 4.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat UDG PF03167.19 KEY66521.1 - 6.3e-23 81.5 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.11 KEY66522.1 - 1.6e-169 564.7 0.0 2.1e-169 564.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF726 PF05277.12 KEY66523.1 - 6e-118 393.7 0.3 7.6e-118 393.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Endotoxin_C2 PF18449.1 KEY66523.1 - 0.014 15.7 7.3 0.052 13.9 1.7 2.5 2 0 0 2 2 2 0 Delta endotoxin Thioesterase PF00975.20 KEY66523.1 - 0.024 14.7 0.1 0.061 13.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain AP3B1_C PF14796.6 KEY66523.1 - 0.025 14.8 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal PE-PPE PF08237.11 KEY66523.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Nop53 PF07767.11 KEY66524.1 - 0.017 14.5 32.1 0.023 14.1 32.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SRP-alpha_N PF04086.13 KEY66524.1 - 0.17 11.8 28.3 0.22 11.4 28.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Thg1C PF14413.6 KEY66525.1 - 2.7e-51 172.8 0.1 3.6e-51 172.4 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KEY66525.1 - 1.2e-50 170.7 0.0 1.8e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.32 KEY66526.1 - 1.3e-11 44.8 3.8 0.0072 17.2 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY66526.1 - 1.1e-08 35.2 0.4 0.0069 16.7 0.0 4.6 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEY66526.1 - 6e-05 22.7 0.4 0.00013 21.6 0.1 1.8 3 0 0 3 3 3 1 PQQ-like domain eIF2A PF08662.11 KEY66526.1 - 0.00016 21.6 0.1 0.91 9.4 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.12 KEY66527.1 - 2.6e-106 355.5 0.0 3.9e-106 354.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KEY66527.1 - 6.1e-99 330.8 0.0 1.1e-98 330.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEY66527.1 - 1.5e-75 253.0 0.0 3.3e-75 251.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KEY66527.1 - 3.9e-59 199.7 0.4 6.4e-59 199.0 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KEY66527.1 - 1.7e-45 154.3 0.2 1.4e-44 151.4 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KEY66527.1 - 1.9e-43 148.1 0.0 4.4e-43 146.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEY66527.1 - 2.5e-36 123.9 0.1 5.8e-36 122.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KEY66527.1 - 8.2 7.0 194.3 0.075 13.4 10.4 13.4 10 4 2 12 12 12 0 RNA polymerase Rpb1 C-terminal repeat FAD_binding_4 PF01565.23 KEY66528.1 - 4.3e-24 84.8 1.2 8.1e-24 83.9 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY66528.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FMN_dh PF01070.18 KEY66529.1 - 2.3e-112 375.5 0.0 2.6e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEY66529.1 - 2.8e-05 23.4 0.1 5.6e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY66529.1 - 5.9e-05 22.2 1.6 0.0016 17.5 0.7 2.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KEY66529.1 - 0.0049 16.3 0.1 0.0073 15.7 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KEY66529.1 - 0.042 13.2 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEY66529.1 - 0.16 11.4 0.1 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 KEY66529.1 - 0.21 10.8 0.1 2.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF4202 PF13875.6 KEY66530.1 - 2e-74 249.5 0.1 2.3e-74 249.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Utp14 PF04615.13 KEY66531.1 - 1.1 7.7 22.1 1.4 7.4 22.1 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 KEY66531.1 - 1.5 7.3 30.0 1.8 7.0 30.0 1.1 1 0 0 1 1 1 0 Macoilin family 14-3-3 PF00244.20 KEY66532.1 - 1.1e-06 28.4 0.0 4.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.8 KEY66534.1 - 1.7e-37 128.7 9.0 1.7e-37 128.7 9.0 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KEY66534.1 - 8.9e-08 30.7 6.0 1.3e-07 30.2 6.0 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KEY66534.1 - 1 10.3 5.5 0.86 10.6 0.4 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Cupin_8 PF13621.6 KEY66535.1 - 4.4e-65 219.9 0.1 5.5e-65 219.6 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KEY66535.1 - 8.3e-06 25.5 0.1 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KEY66535.1 - 0.058 13.8 0.0 0.91 10.0 0.0 2.5 2 0 0 2 2 2 0 JmjC domain, hydroxylase Spb1_C PF07780.12 KEY66536.1 - 1.2e-82 276.7 19.0 1.2e-82 276.7 19.0 2.8 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KEY66536.1 - 3.4e-56 190.2 0.0 5.8e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KEY66536.1 - 4.6e-53 179.4 3.1 4.6e-53 179.4 3.1 4.6 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 KEY66536.1 - 0.032 13.9 0.0 0.094 12.3 0.0 1.8 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 KEY66536.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Dynamin_N PF00350.23 KEY66537.1 - 4.3e-43 147.3 0.0 8.4e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEY66537.1 - 7.8e-14 51.6 0.1 8.8e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KEY66537.1 - 2.2e-05 24.5 0.0 0.00028 20.9 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KEY66537.1 - 0.042 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4872 PF16169.5 KEY66537.1 - 0.075 12.8 0.7 0.21 11.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) AAA_15 PF13175.6 KEY66537.1 - 0.11 12.1 1.1 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KEY66537.1 - 0.17 12.3 3.0 0.18 12.2 0.1 2.5 3 1 0 3 3 3 0 AAA ATPase domain Cation_efflux PF01545.21 KEY66538.1 - 9e-11 41.9 15.9 1.2e-10 41.5 15.9 1.2 1 0 0 1 1 1 1 Cation efflux family Ferrochelatase PF00762.19 KEY66538.1 - 0.043 12.9 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrochelatase DUF5056 PF16479.5 KEY66538.1 - 0.43 10.8 4.5 3.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) PIG-Y PF15159.6 KEY66539.1 - 2.4e-22 79.6 7.9 3.7e-22 79.0 7.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KEY66539.1 - 0.047 14.2 0.5 5.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf-MYND PF01753.18 KEY66540.1 - 1e-07 31.9 20.6 2.6e-07 30.6 20.6 1.7 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 KEY66540.1 - 0.35 11.4 8.7 0.78 10.3 8.7 1.6 1 0 0 1 1 1 0 TAZ zinc finger GoLoco PF02188.17 KEY66540.1 - 0.45 10.1 2.1 0.34 10.5 0.3 1.8 2 0 0 2 2 2 0 GoLoco motif Ebp2 PF05890.12 KEY66541.1 - 1.5e-95 319.8 14.9 1.5e-95 319.8 14.9 2.0 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Cyanate_lyase PF02560.14 KEY66542.1 - 8.2e-32 108.9 0.0 1.2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 KEY66542.1 - 0.00014 21.4 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_31 PF13560.6 KEY66542.1 - 0.00043 20.6 0.0 0.00067 20.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Myb_DNA-binding PF00249.31 KEY66542.1 - 0.029 14.6 0.1 20 5.5 0.0 3.4 3 1 0 3 3 3 0 Myb-like DNA-binding domain HTH_38 PF13936.6 KEY66542.1 - 0.087 12.6 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 KEY66543.1 - 2e-13 50.3 0.0 8.3e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC CENP-B_dimeris PF09026.10 KEY66543.1 - 4.3 7.8 6.7 73 3.8 3.9 3.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UQ_con PF00179.26 KEY66544.1 - 1.5e-18 66.8 0.0 2.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEY66544.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain P5-ATPase PF12409.8 KEY66546.1 - 9.9e-39 132.3 0.3 2.8e-38 130.8 0.0 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KEY66546.1 - 3.5e-28 98.3 0.0 8.9e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEY66546.1 - 3.9e-15 56.7 0.0 4.4e-07 30.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY66546.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEY66546.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) NAP PF00956.18 KEY66547.1 - 2.1e-98 328.8 5.1 2.1e-98 328.8 5.1 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.13 KEY66547.1 - 0.0049 16.9 12.9 0.0096 16.0 12.9 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 KEY66547.1 - 3.2 8.4 7.2 0.26 11.9 0.3 2.4 2 1 0 2 2 2 0 Striatin family BUD22 PF09073.10 KEY66547.1 - 7 5.9 18.1 5.8 6.1 11.3 2.1 2 0 0 2 2 2 0 BUD22 Myosin_head PF00063.21 KEY66548.1 - 3.3e-259 861.7 0.2 5.2e-259 861.1 0.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KEY66548.1 - 2.5e-26 91.9 2.7 2.5e-26 91.9 2.7 2.9 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KEY66548.1 - 7.7e-14 50.1 36.9 5.7e-05 22.6 0.6 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KEY66548.1 - 0.0015 18.3 0.1 0.004 17.0 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF812 PF05667.11 KEY66548.1 - 0.0021 17.1 23.6 0.0039 16.2 23.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CALCOCO1 PF07888.11 KEY66548.1 - 0.0034 16.3 23.3 0.0061 15.5 23.3 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_16 PF13191.6 KEY66548.1 - 0.0039 17.6 0.3 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY66548.1 - 0.0048 17.2 0.0 0.023 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sec34 PF04136.15 KEY66548.1 - 0.04 13.8 7.0 0.025 14.5 4.2 2.1 1 1 0 1 1 1 0 Sec34-like family EzrA PF06160.12 KEY66548.1 - 0.12 10.6 21.8 0.31 9.2 10.3 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.6 KEY66548.1 - 0.17 11.2 29.8 0.017 14.5 14.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KEY66548.1 - 0.24 11.4 7.0 0.26 11.3 4.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOGA PF11365.8 KEY66548.1 - 0.76 10.9 16.8 0.96 10.6 0.4 3.6 3 0 0 3 3 3 0 Protein SOGA Flagellin_N PF00669.20 KEY66548.1 - 0.8 9.8 13.4 0.15 12.2 8.3 2.5 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region TMCO5 PF14992.6 KEY66548.1 - 1.2 8.7 18.7 3.1 7.3 18.7 1.7 1 0 0 1 1 1 0 TMCO5 family zf-C4H2 PF10146.9 KEY66548.1 - 1.3 9.3 9.8 5.2 7.3 9.8 2.1 1 0 0 1 1 1 0 Zinc finger-containing protein Vps51 PF08700.11 KEY66548.1 - 4.4 7.5 8.4 9.8 6.3 0.6 3.3 3 0 0 3 3 2 0 Vps51/Vps67 Tropomyosin_1 PF12718.7 KEY66548.1 - 4.4 7.5 30.6 0.62 10.2 6.4 2.7 1 1 1 2 2 2 0 Tropomyosin like KASH_CCD PF14662.6 KEY66548.1 - 4.5 7.0 30.7 1.8 8.3 9.1 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 KEY66548.1 - 4.7 6.4 26.4 6.1 6.1 13.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 KEY66548.1 - 5.4 7.5 28.8 3.4 8.1 6.6 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Snapin_Pallidin PF14712.6 KEY66548.1 - 6.7 7.2 20.2 2.2 8.7 6.0 3.5 2 1 1 3 3 3 0 Snapin/Pallidin ING PF12998.7 KEY66548.1 - 9 7.0 12.4 1.1 9.8 1.6 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 KEY66548.1 - 9.7 6.2 13.1 5 7.2 0.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_18 PF13238.6 KEY66549.1 - 8.2e-28 97.6 1.0 1.5e-27 96.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KEY66549.1 - 3e-09 37.4 0.0 2.2e-08 34.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KEY66549.1 - 2.2e-06 27.8 0.1 0.0017 18.4 0.0 2.3 1 1 1 2 2 2 2 Adenylate kinase AAA_33 PF13671.6 KEY66549.1 - 4.3e-06 26.9 0.2 0.0034 17.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 KEY66549.1 - 5.8e-05 22.9 0.4 0.28 10.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.29 KEY66549.1 - 9.2e-05 22.9 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEY66549.1 - 0.00017 21.8 2.7 0.00038 20.7 2.7 1.8 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KEY66549.1 - 0.00027 20.9 1.8 0.36 10.7 0.1 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 KEY66549.1 - 0.00051 20.3 0.2 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KEY66549.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 NTPase Hydin_ADK PF17213.3 KEY66549.1 - 0.00075 19.8 0.0 0.0018 18.6 0.0 1.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KEY66549.1 - 0.0018 18.7 0.1 0.0049 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KEY66549.1 - 0.0021 17.6 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 KEY66549.1 - 0.0073 16.3 0.1 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SKI PF01202.22 KEY66549.1 - 0.011 15.9 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 KEY66549.1 - 0.016 15.6 2.1 0.13 12.6 0.4 2.3 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEY66549.1 - 0.02 14.7 0.4 0.041 13.7 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KEY66549.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin2 PF13189.6 KEY66549.1 - 0.024 14.7 0.0 0.051 13.7 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_24 PF13479.6 KEY66549.1 - 0.029 14.1 1.4 0.046 13.4 0.2 2.1 2 2 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KEY66549.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KEY66549.1 - 0.052 13.6 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KEY66549.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KEY66549.1 - 0.086 12.5 4.3 1.9 8.1 0.5 3.0 2 1 1 3 3 3 0 AAA domain MeaB PF03308.16 KEY66549.1 - 0.095 11.7 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_3 PF07726.11 KEY66549.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KEY66549.1 - 0.14 11.5 0.5 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RuvB_N PF05496.12 KEY66549.1 - 0.15 11.8 0.2 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ham1p_like PF01725.16 KEY66550.1 - 1e-52 178.8 0.0 1.3e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 KEY66551.1 - 1.2e-63 214.4 0.0 1.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.13 KEY66551.1 - 0.06 12.9 0.0 0.76 9.3 0.0 2.2 1 1 1 2 2 2 0 Staphopain peptidase C47 tRNA-synt_2b PF00587.25 KEY66552.1 - 2.3e-36 125.4 0.0 3.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KEY66552.1 - 1.2e-17 64.1 7.6 2.3e-17 63.2 7.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WAPL PF07814.13 KEY66553.1 - 4.5e-49 167.2 0.3 7.9e-49 166.4 0.3 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 KEY66553.1 - 9.5e-42 142.4 0.1 1.4e-41 141.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY66553.1 - 1.8e-13 50.8 0.0 3.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY66553.1 - 0.0007 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEY66553.1 - 0.0025 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEY66553.1 - 0.003 17.6 0.2 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF971 PF06155.12 KEY66553.1 - 0.036 14.7 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) AAA_14 PF13173.6 KEY66553.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.6 KEY66554.1 - 1.4e-77 259.8 0.0 1.9e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEY66554.1 - 0.00083 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 KEY66555.1 - 3.8e-29 100.5 0.4 4.7e-29 100.3 0.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CWC PF14375.6 KEY66555.1 - 0.054 13.9 0.4 0.11 12.9 0.4 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC PHD_4 PF16866.5 KEY66555.1 - 0.082 13.0 0.5 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.15 KEY66555.1 - 0.13 12.4 1.1 5.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_S3Ae PF01015.18 KEY66556.1 - 1.9e-88 295.3 1.9 2.5e-88 295.0 1.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KEY66556.1 - 0.028 14.9 0.0 0.089 13.3 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor SUI1 NEMO PF11577.8 KEY66556.1 - 0.036 14.1 0.3 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Erythro-docking PF09277.11 KEY66556.1 - 0.12 12.3 0.3 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Abhydrolase_1 PF00561.20 KEY66557.1 - 2.4e-24 86.4 0.0 6.6e-19 68.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY66557.1 - 1.7e-15 58.2 0.0 2.6e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY66557.1 - 5.6e-11 42.2 0.2 1.4e-10 40.9 0.2 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEY66557.1 - 1.1e-07 32.2 0.0 1.6e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KEY66557.1 - 2.2e-07 30.8 0.2 2.4e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KEY66557.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 KEY66557.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ndr PF03096.14 KEY66557.1 - 0.036 12.8 0.0 0.096 11.4 0.0 1.6 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.7 KEY66557.1 - 0.045 12.7 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LCAT PF02450.15 KEY66557.1 - 0.055 12.6 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3530 PF12048.8 KEY66557.1 - 0.059 12.8 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) WCCH PF03716.14 KEY66558.1 - 0.082 12.6 6.1 0.48 10.1 0.7 2.5 2 0 0 2 2 2 0 WCCH motif WD40 PF00400.32 KEY66559.1 - 5.4e-32 109.3 17.0 2.5e-06 28.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KEY66559.1 - 1.4e-07 31.3 0.2 1.4e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KEY66559.1 - 2e-06 28.0 0.1 0.02 15.2 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KEY66559.1 - 1.2e-05 25.0 0.1 3.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KEY66559.1 - 0.0004 19.2 1.0 1.7 7.2 0.0 4.0 3 1 0 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEY66559.1 - 0.027 13.0 0.1 0.054 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KEY66559.1 - 0.052 12.5 0.1 0.41 9.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KEY66559.1 - 0.1 12.1 0.1 1 8.9 0.1 2.3 1 1 0 1 1 1 0 PQQ-like domain Pectate_lyase_3 PF12708.7 KEY66560.1 - 1.7e-96 322.2 13.8 5.4e-86 287.9 4.9 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEY66560.1 - 4.4e-05 23.1 2.6 0.096 12.4 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Scs3p PF10261.9 KEY66561.1 - 2.7e-76 256.3 7.6 3.5e-76 256.0 7.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 KEY66562.1 - 3.3e-20 72.0 0.1 5.5e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 KEY66562.1 - 0.033 14.9 0.0 0.061 14.1 0.0 1.4 1 0 0 1 1 1 0 HIT domain PBP1_TM PF14812.6 KEY66563.1 - 0.78 10.2 5.9 2.1 8.7 5.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Man-6-P_recep PF02157.15 KEY66564.1 - 3.6e-13 49.2 0.0 8.4e-13 48.0 0.0 1.5 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KEY66564.1 - 1.3e-11 44.8 0.0 3.1e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KEY66564.1 - 3e-05 24.1 0.1 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 KEY66565.1 - 1.6e-158 528.0 3.7 1.9e-158 527.7 3.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KEY66565.1 - 3.1e-05 23.6 1.0 6.5e-05 22.6 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_hydro_3_C PF01915.22 KEY66566.1 - 5.3e-41 140.8 0.0 1.6e-40 139.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY66566.1 - 1.8e-34 119.6 0.0 3.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY66566.1 - 4.7e-19 68.3 0.1 9.2e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Granulin PF00396.18 KEY66569.1 - 0.69 10.3 17.1 1.5e+03 -0.4 17.1 2.5 1 1 0 1 1 1 0 Granulin HET PF06985.11 KEY66570.1 - 8.1e-19 68.4 0.0 1.4e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Prominin PF05478.11 KEY66570.1 - 0.011 13.8 0.5 0.017 13.2 0.5 1.1 1 0 0 1 1 1 0 Prominin ADH_zinc_N PF00107.26 KEY66571.1 - 6e-30 103.9 0.4 1.5e-29 102.6 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY66571.1 - 1.5e-15 58.4 0.0 3.9e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY66571.1 - 1.4e-10 41.0 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KEY66571.1 - 8.6e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KEY66571.1 - 0.00025 21.3 0.0 0.00068 19.9 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain ELFV_dehydrog PF00208.21 KEY66571.1 - 0.049 13.3 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2461 PF09365.10 KEY66571.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) WCCH PF03716.14 KEY66572.1 - 0.037 13.7 10.6 0.96 9.2 1.2 3.3 3 0 0 3 3 3 0 WCCH motif Gly_transf_sug PF04488.15 KEY66573.1 - 7.1e-07 29.8 0.0 9.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KEY66573.1 - 0.18 11.0 0.1 0.26 10.5 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HemN_C PF06969.16 KEY66574.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain AMP-binding PF00501.28 KEY66575.1 - 1.2e-64 218.5 0.0 1.8e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEY66575.1 - 8e-14 51.7 0.0 2.3e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KEY66575.1 - 7.9e-05 22.2 4.9 0.71 9.7 0.0 6.2 6 1 0 6 6 6 1 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 KEY66575.1 - 0.007 17.3 0.0 2 9.4 0.1 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 KEY66575.1 - 5.9 6.7 12.4 25 4.7 0.2 5.8 6 1 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase RRM_1 PF00076.22 KEY66576.1 - 5.7e-27 93.3 1.3 2.7e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY66576.1 - 3.5e-06 26.6 0.0 0.00088 18.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KEY66576.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.17 KEY66577.1 - 7.3e-61 205.4 3.1 1.8e-60 204.2 3.1 1.6 1 1 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KEY66577.1 - 0.054 13.0 0.2 0.078 12.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 KEY66577.1 - 0.21 11.9 3.4 1.2 9.3 0.1 2.3 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Terminase_2 PF03592.16 KEY66577.1 - 0.28 11.6 5.7 1.2 9.6 5.7 2.0 1 1 0 1 1 1 0 Terminase small subunit Suf PF05843.14 KEY66578.1 - 1.9e-11 44.5 7.7 0.038 14.0 1.4 6.2 4 1 2 6 6 6 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KEY66578.1 - 7e-08 32.5 8.3 0.31 11.0 0.1 7.0 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KEY66578.1 - 2e-07 30.5 3.4 1.5e-05 24.4 0.6 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY66578.1 - 3.5e-07 30.5 22.7 2.6 9.1 0.0 10.6 9 3 4 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY66578.1 - 2.5e-06 27.7 2.5 3.5 8.0 0.0 6.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY66578.1 - 2.5e-06 27.3 2.7 0.17 12.2 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KEY66578.1 - 0.00073 18.7 8.0 0.04 13.0 0.1 5.8 3 2 3 7 7 7 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KEY66578.1 - 0.0019 18.6 0.5 22 5.7 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KEY66578.1 - 0.0047 16.7 0.6 0.045 13.4 0.1 3.0 4 1 0 4 4 4 1 26S proteasome subunit RPN7 MIT PF04212.18 KEY66578.1 - 0.14 12.2 0.3 1.6 8.9 0.1 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KEY66578.1 - 0.94 9.4 9.3 1.2e+02 2.8 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat PolyA_pol PF01743.20 KEY66580.1 - 5.1e-28 98.0 0.2 1.1e-27 97.0 0.2 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KEY66580.1 - 1.2e-09 37.7 0.0 3.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KEY66580.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Tti2 PF10521.9 KEY66581.1 - 3.5e-76 256.4 0.2 3.5e-76 256.4 0.2 1.7 2 0 0 2 2 2 1 Tti2 family MEDS PF14417.6 KEY66581.1 - 0.13 12.1 0.1 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF2205 PF10224.9 KEY66581.1 - 0.21 11.6 1.2 10 6.2 0.1 3.2 3 0 0 3 3 3 0 Short coiled-coil protein RPEL PF02755.15 KEY66581.1 - 0.22 11.3 0.7 0.64 9.8 0.2 2.1 2 0 0 2 2 2 0 RPEL repeat Syja_N PF02383.18 KEY66582.1 - 1.3e-76 257.9 0.0 2.3e-76 257.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Sec7 PF01369.20 KEY66583.1 - 8.2e-64 214.6 0.0 1.7e-63 213.6 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KEY66583.1 - 1e-14 54.7 0.0 5.1e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KEY66583.1 - 0.004 16.8 0.1 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Anp1 PF03452.14 KEY66584.1 - 1.3e-113 378.8 0.0 1.3e-113 378.8 0.0 2.2 3 0 0 3 3 3 1 Anp1 Rrn6 PF10214.9 KEY66584.1 - 0.025 13.1 1.0 0.032 12.7 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Glycos_transf_2 PF00535.26 KEY66584.1 - 0.033 14.0 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Smg8_Smg9 PF10220.9 KEY66584.1 - 1.2 7.3 6.7 1.5 7.0 6.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 O-antigen_lig PF13425.6 KEY66584.1 - 2.5 6.8 4.1 3.6 6.3 4.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TAF4 PF05236.14 KEY66584.1 - 3.3 7.4 14.0 4.7 6.9 14.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.12 KEY66584.1 - 5.9 6.6 11.2 9.2 6.0 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_PH PF01138.21 KEY66585.1 - 9.9e-27 94.0 0.1 2.5e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Mannosidase_ig PF17786.1 KEY66586.1 - 8.3e-14 52.0 0.3 2e-13 50.8 0.3 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KEY66586.1 - 9.7e-08 31.7 0.0 3.2e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KEY66586.1 - 5.2e-06 27.1 0.1 3.4e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KEY66586.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain zf-C3HC4_3 PF13920.6 KEY66587.1 - 2e-08 34.0 12.9 3.3e-08 33.3 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY66587.1 - 0.07 13.0 12.9 0.12 12.2 12.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 tRNA_int_endo PF01974.17 KEY66588.1 - 2.7e-10 40.2 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain B PF02216.16 KEY66588.1 - 0.00054 19.9 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 B domain PAXNEB PF05625.11 KEY66589.1 - 8.1e-101 337.8 0.0 9.3e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.15 KEY66590.1 - 1.4e-45 154.9 0.0 1.5e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KEY66590.1 - 0.0025 17.9 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G NB-ARC PF00931.22 KEY66590.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain NUDIX PF00293.28 KEY66591.1 - 8.8e-12 45.2 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KEY66591.1 - 2.1e-09 37.4 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) CCDC142 PF14923.6 KEY66591.1 - 0.055 12.2 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 DUF775 PF05603.12 KEY66592.1 - 2.7e-55 187.0 0.1 1.7e-54 184.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF775) GDA1_CD39 PF01150.17 KEY66593.1 - 4.8e-106 355.0 0.0 6.9e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_5 PF14634.6 KEY66594.1 - 4.5e-07 29.7 4.7 7.1e-07 29.1 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain CCDC14 PF15254.6 KEY66594.1 - 0.0012 17.6 5.4 0.0017 17.1 5.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 Ax_dynein_light PF10211.9 KEY66594.1 - 0.0038 17.2 2.7 0.0061 16.5 2.7 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain zf-RING_UBOX PF13445.6 KEY66594.1 - 0.0046 17.0 1.6 0.018 15.1 0.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEY66594.1 - 0.0062 16.9 5.2 0.01 16.1 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEY66594.1 - 0.0091 15.9 4.2 0.017 15.0 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY66594.1 - 0.011 15.6 4.8 0.02 14.7 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEY66594.1 - 0.014 15.3 4.5 0.024 14.5 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY66594.1 - 0.017 14.9 3.1 0.06 13.2 3.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4201 PF13870.6 KEY66594.1 - 0.021 14.5 8.2 0.031 14.0 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Streptin-Immun PF11083.8 KEY66594.1 - 0.028 14.8 2.0 0.059 13.8 2.0 1.5 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Herpes_UL25 PF01499.16 KEY66594.1 - 0.028 12.9 1.6 0.038 12.5 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Tropomyosin_1 PF12718.7 KEY66594.1 - 0.038 14.2 7.9 0.058 13.5 7.9 1.2 1 0 0 1 1 1 0 Tropomyosin like Spc24 PF08286.11 KEY66594.1 - 0.074 13.3 7.8 0.077 13.2 6.5 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 V-ATPase_G_2 PF16999.5 KEY66594.1 - 0.17 12.3 7.3 0.27 11.7 7.3 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Tho2 PF11262.8 KEY66594.1 - 0.18 11.0 5.1 0.25 10.5 5.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF948 PF06103.11 KEY66594.1 - 0.23 11.7 0.5 0.38 11.0 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KEY66594.1 - 0.4 11.2 8.5 0.62 10.6 8.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 KEY66594.1 - 0.47 10.5 4.7 0.91 9.6 4.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SOAR PF16533.5 KEY66594.1 - 0.63 10.0 5.4 11 6.0 0.1 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region DivIC PF04977.15 KEY66594.1 - 0.76 9.6 4.9 0.44 10.3 2.3 1.9 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 KEY66594.1 - 1.2 9.6 6.8 1.5 9.3 6.3 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) GrpE PF01025.19 KEY66594.1 - 1.6 8.4 6.9 1.1 8.9 4.8 1.6 1 1 1 2 2 2 0 GrpE zinc_ribbon_9 PF14369.6 KEY66594.1 - 2.4 8.5 5.2 0.88 9.9 1.7 2.0 1 1 1 2 2 2 0 zinc-ribbon OmpH PF03938.14 KEY66594.1 - 3.4 8.0 12.1 5.5 7.3 12.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipase_GDSL_2 PF13472.6 KEY66595.1 - 5.5e-12 46.4 0.9 7.5e-12 46.0 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SASA PF03629.18 KEY66595.1 - 0.0018 18.0 0.2 0.01 15.5 0.2 1.9 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Lipase_GDSL PF00657.22 KEY66595.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SurA_N_2 PF13623.6 KEY66595.1 - 0.047 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Fungal_trans PF04082.18 KEY66596.1 - 2.6e-23 82.4 0.4 5.9e-23 81.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66596.1 - 3.4e-07 30.3 12.6 6.1e-07 29.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.11 KEY66596.1 - 0.091 13.1 1.5 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal ThiF PF00899.21 KEY66597.1 - 1.2e-10 41.2 0.0 3.6e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 ThiF family adh_short PF00106.25 KEY66598.1 - 4.1e-51 173.2 0.0 5.4e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66598.1 - 1.1e-35 123.4 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66598.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY66598.1 - 0.00052 20.3 0.1 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KEY66598.1 - 0.0015 17.7 0.0 0.0055 15.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEY66598.1 - 0.039 13.4 0.1 0.11 12.0 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pribosyltran_N PF13793.6 KEY66599.1 - 5.3e-43 145.7 0.0 1.6e-41 140.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEY66599.1 - 7.6e-33 114.1 0.0 1.6e-27 96.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEY66599.1 - 1.6e-07 31.0 0.0 0.00048 19.7 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 KEY66600.1 - 1.1e-47 162.6 0.0 1.8e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KEY66600.1 - 0.098 13.0 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 XPG I-region PAP_assoc PF03828.19 KEY66601.1 - 2.5e-18 66.0 0.1 8e-17 61.2 0.1 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEY66601.1 - 0.024 14.9 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain Retrotrans_gag PF03732.17 KEY66601.1 - 0.06 13.6 1.2 21 5.4 0.0 3.3 2 1 1 3 3 3 0 Retrotransposon gag protein ATP-cone PF03477.16 KEY66601.1 - 0.13 12.9 0.5 0.63 10.6 0.0 2.4 2 1 1 3 3 3 0 ATP cone domain TFIIF_alpha PF05793.12 KEY66602.1 - 0.00074 18.2 47.4 0.0011 17.6 46.5 1.6 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDI PF02234.19 KEY66602.1 - 0.64 10.3 7.0 0.74 10.1 0.8 3.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Bud13 PF09736.9 KEY66603.1 - 1.4e-51 174.7 10.2 1.4e-51 174.7 10.2 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.7 KEY66604.1 - 2.3e-110 369.3 0.0 7.2e-110 367.7 0.0 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.21 KEY66605.1 - 1.7e-20 73.4 21.7 2.5e-20 72.8 21.7 1.3 1 0 0 1 1 1 1 Snf7 ASL_C2 PF14698.6 KEY66605.1 - 0.28 11.9 1.5 1.1 10.1 0.0 2.7 2 1 0 2 2 2 0 Argininosuccinate lyase C-terminal YlqD PF11068.8 KEY66605.1 - 3.8 7.9 19.5 2.1 8.7 4.8 2.6 2 0 0 2 2 2 0 YlqD protein zf-C3HC4_2 PF13923.6 KEY66606.1 - 5.7e-12 45.3 9.5 5.7e-12 45.3 9.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY66606.1 - 2.4e-08 33.7 8.6 2.4e-08 33.7 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY66606.1 - 3.5e-07 30.1 7.3 3.5e-07 30.1 7.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY66606.1 - 1.8e-06 27.7 6.7 1.8e-06 27.7 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY66606.1 - 2.7e-06 27.4 8.0 2.7e-06 27.4 8.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KEY66606.1 - 7.6e-06 26.2 9.1 7.6e-06 26.2 9.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KEY66606.1 - 8.6e-06 25.6 8.7 8.6e-06 25.6 8.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KEY66606.1 - 3.5e-05 23.6 2.8 3.5e-05 23.6 2.8 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KEY66606.1 - 7.4e-05 22.5 10.9 0.0026 17.6 7.0 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KEY66606.1 - 0.00016 21.9 3.1 0.00016 21.9 3.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KEY66606.1 - 0.0091 16.1 5.1 0.0091 16.1 5.1 1.6 2 0 0 2 2 2 1 zinc RING finger of MSL2 SAP PF02037.27 KEY66606.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 SAP domain Mob_synth_C PF06463.13 KEY66606.1 - 0.063 13.2 0.9 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-WRNIP1_ubi PF18279.1 KEY66606.1 - 0.19 12.5 4.3 0.23 12.2 0.2 3.1 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_4 PF14570.6 KEY66606.1 - 0.28 11.0 10.0 0.13 12.1 5.4 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KEY66606.1 - 0.68 9.8 9.0 0.06 13.2 3.5 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.12 KEY66606.1 - 2.8 8.0 10.4 8.1 6.5 4.4 2.4 2 0 0 2 2 2 0 zinc-ribbons CDC27 PF09507.10 KEY66607.1 - 4.4e-83 280.1 35.0 1.9e-82 277.9 35.0 2.1 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 dbPDZ_assoc PF16610.5 KEY66607.1 - 0.57 10.4 8.3 1.7 8.9 0.9 2.7 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 DUF1682 PF07946.14 KEY66607.1 - 8 5.6 14.1 0.12 11.5 5.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1682) Aminotran_1_2 PF00155.21 KEY66608.1 - 1.2e-25 90.4 0.0 1.6e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEY66608.1 - 0.011 14.5 0.0 0.035 12.9 0.0 1.7 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Glyco_hydro_125 PF06824.11 KEY66609.1 - 6.3e-176 585.3 0.0 7.3e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MOZ_SAS PF01853.18 KEY66610.1 - 8.3e-81 269.9 0.2 1.1e-80 269.5 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEY66610.1 - 4.4e-22 77.5 0.7 8.8e-22 76.5 0.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KEY66610.1 - 8.7e-18 64.0 0.0 7.1e-17 61.0 0.0 2.6 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KEY66610.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY66610.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_T PF00929.24 KEY66611.1 - 1.9e-14 54.5 0.0 4.2e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KEY66611.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease RNase_H2_suC PF08615.11 KEY66612.1 - 8.1e-24 84.4 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM PF00493.23 KEY66613.1 - 4.9e-103 343.0 0.8 1.2e-102 341.8 0.3 1.8 1 1 1 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEY66613.1 - 1.6e-38 131.4 0.2 3.1e-38 130.5 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KEY66613.1 - 9.9e-33 112.6 0.1 2.4e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KEY66613.1 - 7.4e-26 90.4 0.3 2.5e-25 88.7 0.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY66613.1 - 3.2e-23 82.3 0.1 1.3e-22 80.4 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEY66613.1 - 2.5e-07 30.3 0.0 7.3e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEY66613.1 - 0.00091 19.0 0.0 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEY66613.1 - 0.0013 18.6 0.2 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GIDA_assoc PF13932.6 KEY66613.1 - 0.011 16.0 0.5 0.024 14.8 0.5 1.5 1 0 0 1 1 1 0 GidA associated domain AAA_5 PF07728.14 KEY66613.1 - 0.033 14.2 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CCDC53 PF10152.9 KEY66613.1 - 0.036 14.5 1.5 0.11 12.9 0.5 2.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex F1F0-ATPsyn_F PF10791.9 KEY66615.1 - 2.3e-40 137.0 0.3 2.6e-40 136.8 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KEY66615.1 - 0.022 15.1 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 KEY66616.1 - 7.2e-34 115.9 1.4 9.9e-34 115.5 1.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.9 KEY66617.1 - 2.1e-28 99.1 0.0 2.8e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KEY66617.1 - 5.4e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 LisH Torus PF16131.5 KEY66618.1 - 2.6e-43 147.2 0.1 3.3e-42 143.6 0.1 2.3 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KEY66618.1 - 2e-08 33.9 0.0 4.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KEY66618.1 - 0.00039 20.2 0.5 0.00076 19.3 0.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 KEY66618.1 - 0.00045 20.2 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KEY66618.1 - 0.00056 19.9 0.7 0.00056 19.9 0.7 1.9 2 0 0 2 2 2 1 Zinc finger domain Alpha_Helical PF18489.1 KEY66618.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Alpha helical domain zf-CCCH_4 PF18044.1 KEY66618.1 - 0.35 10.7 2.2 0.75 9.7 2.2 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger PRK PF00485.18 KEY66619.1 - 7.7e-58 195.5 0.0 1.1e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KEY66619.1 - 7.8e-40 136.5 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 KEY66619.1 - 5.6e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KEY66619.1 - 7.1e-06 26.2 0.0 2.6e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEY66619.1 - 2.9e-05 23.5 0.0 0.0001 21.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KEY66619.1 - 2.9e-05 24.6 0.0 7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEY66619.1 - 6.9e-05 23.3 1.9 0.091 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KEY66619.1 - 0.0013 18.0 0.1 0.009 15.2 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 KEY66619.1 - 0.0032 18.0 0.1 0.0082 16.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KEY66619.1 - 0.0059 17.0 0.0 0.035 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEY66619.1 - 0.0059 16.5 0.4 0.018 15.0 0.1 2.0 3 0 0 3 3 2 1 NACHT domain Cytidylate_kin PF02224.18 KEY66619.1 - 0.0068 16.2 0.2 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase DUF87 PF01935.17 KEY66619.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KEY66619.1 - 0.0098 16.2 0.0 0.043 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY66619.1 - 0.011 15.5 0.1 0.03 14.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY66619.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KEY66619.1 - 0.026 15.0 0.0 0.076 13.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEY66619.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY66619.1 - 0.033 14.6 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KEY66619.1 - 0.035 13.2 0.1 0.073 12.1 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.20 KEY66619.1 - 0.037 13.9 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_5 PF07728.14 KEY66619.1 - 0.063 13.3 0.0 0.42 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 KEY66619.1 - 0.12 12.3 0.1 0.67 9.8 0.1 2.2 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_25 PF13481.6 KEY66619.1 - 0.16 11.5 0.2 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEY66619.1 - 0.17 11.9 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 KEY66619.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pyr_redox_2 PF07992.14 KEY66620.1 - 3.3e-42 144.7 0.0 6e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY66620.1 - 2.1e-13 50.6 0.0 4.6e-10 39.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KEY66620.1 - 2.9e-07 29.6 0.1 7.6e-07 28.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEY66620.1 - 1.1e-06 28.0 0.5 3.4e-06 26.5 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KEY66620.1 - 7.1e-05 22.1 1.2 0.00018 20.8 0.4 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KEY66620.1 - 7.5e-05 23.1 0.2 0.00021 21.7 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair HBM PF16591.5 KEY66620.1 - 0.013 15.0 0.4 0.027 13.9 0.4 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain bVLRF1 PF18826.1 KEY66620.1 - 0.015 15.1 0.1 0.037 13.9 0.1 1.6 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor PCRF PF03462.18 KEY66620.1 - 0.052 13.4 0.3 17 5.2 0.0 2.5 2 0 0 2 2 2 0 PCRF domain FAD_binding_2 PF00890.24 KEY66620.1 - 0.14 11.2 0.3 13 4.7 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain ApoLp-III PF07464.11 KEY66620.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RdDM_RDM1 PF09187.10 KEY66620.1 - 0.18 11.9 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Nop53 PF07767.11 KEY66621.1 - 5.3e-110 368.5 33.9 6.4e-110 368.3 33.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.9 KEY66621.1 - 0.056 11.9 8.3 0.082 11.4 8.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ras PF00071.22 KEY66622.1 - 9e-59 197.7 0.5 1.5e-58 197.0 0.5 1.3 1 0 0 1 1 1 1 Ras family Kei1 PF08552.11 KEY66622.1 - 1.3e-57 194.8 4.7 3.5e-57 193.4 4.7 1.8 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Roc PF08477.13 KEY66622.1 - 6.9e-37 126.3 0.4 1.5e-36 125.2 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY66622.1 - 1.3e-17 63.9 0.3 1.9e-17 63.3 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY66622.1 - 1.7e-05 24.4 0.1 6.7e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KEY66622.1 - 5.3e-05 22.7 0.1 9.5e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEY66622.1 - 0.00012 22.1 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEY66622.1 - 0.00017 21.0 0.5 0.00025 20.5 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KEY66622.1 - 0.0015 18.5 0.1 0.38 10.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FlgH PF02107.16 KEY66622.1 - 0.05 13.2 0.4 0.086 12.5 0.4 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein SPC12 PF06645.13 KEY66622.1 - 0.62 10.2 5.7 0.2 11.7 1.0 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.22 KEY66623.1 - 2.7e-53 179.7 0.2 1.3e-49 167.7 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KEY66623.1 - 1.9e-31 107.7 0.0 1.6e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KEY66623.1 - 6.7e-30 104.2 0.0 1.4e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KEY66623.1 - 8.8e-08 32.2 0.2 2.4e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPATA3 PF15662.5 KEY66623.1 - 0.13 12.9 3.1 2.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Chitin_synth_1 PF01644.17 KEY66624.1 - 6.9e-77 257.0 0.0 1e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEY66624.1 - 9.9e-28 95.9 0.1 2.1e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEY66624.1 - 1.7e-25 89.7 3.9 1.8e-20 73.1 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEY66624.1 - 1.4e-07 31.6 3.6 4.6e-07 29.9 3.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF2070 PF09843.9 KEY66624.1 - 0.1 10.9 6.9 0.14 10.4 6.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_32N PF00251.20 KEY66625.1 - 4.9e-76 256.2 2.8 6.3e-76 255.8 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY66625.1 - 1.2e-06 28.6 0.2 2.1e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF3140 PF11338.8 KEY66626.1 - 0.025 15.0 0.2 9.6 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Sugar_tr PF00083.24 KEY66627.1 - 5.8e-93 312.2 28.0 7.3e-93 311.9 28.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66627.1 - 6.1e-22 78.0 40.0 3.7e-18 65.6 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_1 PF00190.22 KEY66628.1 - 1.5e-17 63.6 1.5 3.1e-17 62.6 1.5 1.5 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KEY66628.1 - 0.042 13.6 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Peptidase_M50B PF13398.6 KEY66629.1 - 4.4e-59 199.5 19.6 5.3e-59 199.2 19.6 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KEY66629.1 - 0.0037 16.6 0.1 0.0081 15.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 KEY66629.1 - 0.058 13.2 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M36 PF02128.15 KEY66629.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) CD225 PF04505.12 KEY66629.1 - 3.7 7.8 9.2 1.8 8.7 0.6 3.4 2 1 1 3 3 3 0 Interferon-induced transmembrane protein Abhydrolase_1 PF00561.20 KEY66630.1 - 9.5e-18 64.8 0.4 1.4e-17 64.2 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY66630.1 - 1.9e-12 48.3 1.5 2.8e-12 47.7 1.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY66630.1 - 9.1e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BTB PF00651.31 KEY66631.1 - 1.3e-08 35.1 0.0 3.5e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Fip1 PF05182.13 KEY66632.1 - 1.5e-19 69.2 1.5 2.7e-19 68.4 1.5 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 KEY66633.1 - 6.9e-31 106.9 153.9 8.6e-11 42.5 35.0 5.2 2 1 4 6 6 6 5 Nucleoporin FG repeat region DUF1451 PF07295.11 KEY66633.1 - 0.047 13.7 0.1 0.4 10.7 0.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF812 PF05667.11 KEY66633.1 - 0.053 12.4 7.2 0.06 12.2 6.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Ndc1_Nup PF09531.10 KEY66633.1 - 5.9 5.5 10.1 11 4.6 10.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_3_Rpc31 PF11705.8 KEY66634.1 - 2.3e-62 211.2 1.7 3e-62 210.8 1.7 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 KEY66634.1 - 0.11 10.7 6.2 0.14 10.4 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5523 PF17661.1 KEY66634.1 - 0.17 11.6 3.6 0.24 11.1 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Sec7 PF01369.20 KEY66636.1 - 9.9e-71 237.2 1.1 9.9e-71 237.2 1.1 2.5 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KEY66636.1 - 3.7e-40 137.4 3.1 3.7e-40 137.4 3.1 4.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KEY66636.1 - 4.6e-35 119.3 6.8 4.3e-32 109.8 0.1 5.9 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 KEY66636.1 - 4.1e-22 78.7 4.0 8.2e-21 74.5 0.3 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RIH_assoc PF08454.11 KEY66636.1 - 0.19 11.6 1.0 4.8 7.1 0.1 3.6 3 0 0 3 3 3 0 RyR and IP3R Homology associated Hph PF13694.6 KEY66636.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.0 3 1 0 3 3 3 0 Sec63/Sec62 complex-interacting family 2-oxoacid_dh PF00198.23 KEY66637.1 - 3.6e-75 252.4 0.1 4.7e-75 252.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEY66637.1 - 2e-19 69.2 1.0 4e-19 68.2 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEY66637.1 - 1.8e-12 47.4 0.7 5.4e-12 45.9 0.7 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KEY66637.1 - 0.0031 18.0 1.4 0.013 16.0 0.1 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3614) Fungal_trans_2 PF11951.8 KEY66638.1 - 7.3e-49 166.6 1.4 9.2e-49 166.3 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66638.1 - 0.00031 20.8 1.6 0.00051 20.1 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rib_5-P_isom_A PF06026.14 KEY66640.1 - 3.3e-46 157.0 0.0 4.3e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF1308 PF07000.11 KEY66641.1 - 1.3e-05 25.2 0.0 3.5e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Glyco_hydro_43 PF04616.14 KEY66642.1 - 2e-65 221.0 1.3 2.5e-65 220.6 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY66642.1 - 2.3e-21 76.4 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF3433 PF11915.8 KEY66643.1 - 4.7e-23 81.5 25.3 1.6e-17 63.7 1.7 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KEY66643.1 - 0.15 12.2 2.2 0.22 11.7 0.2 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Spo7 PF03907.13 KEY66643.1 - 0.2 11.1 0.4 0.41 10.1 0.4 1.4 1 0 0 1 1 1 0 Spo7-like protein Ribosomal_60s PF00428.19 KEY66644.1 - 0.13 12.9 3.3 0.22 12.1 3.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein AAA PF00004.29 KEY66645.1 - 3.2e-15 56.7 0.0 6.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY66645.1 - 0.0045 17.0 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY66645.1 - 0.0048 17.2 2.6 0.11 12.7 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY66645.1 - 0.013 15.9 0.7 0.078 13.4 0.6 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KEY66645.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEY66645.1 - 0.065 13.0 0.0 0.065 13.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KEY66645.1 - 0.16 11.3 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4661 PF15576.6 KEY66645.1 - 0.19 11.6 19.5 0.41 10.5 19.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) SRP-alpha_N PF04086.13 KEY66645.1 - 6.7 6.5 28.7 4.6 7.1 25.8 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PKD_channel PF08016.12 KEY66646.1 - 2.5e-06 26.5 18.5 0.00012 20.9 17.7 2.4 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KEY66646.1 - 6.2e-06 25.6 23.5 0.00035 19.9 24.7 2.4 2 1 0 2 2 2 1 Ion transport protein TolA_bind_tri PF16331.5 KEY66646.1 - 0.25 11.4 1.5 0.5 10.5 1.5 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Macro PF01661.21 KEY66647.1 - 1.1e-41 141.5 0.0 1.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.21 KEY66648.1 - 6.1e-101 337.4 0.0 1e-100 336.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEY66648.1 - 2.8e-32 112.0 0.0 1.1e-31 110.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain SprT-like PF10263.9 KEY66649.1 - 0.065 13.1 0.7 0.38 10.6 0.3 2.3 2 0 0 2 2 2 0 SprT-like family ABC_tran PF00005.27 KEY66651.1 - 2.9e-47 160.6 0.2 7.1e-24 84.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KEY66651.1 - 1e-30 105.6 0.5 9.6e-30 102.5 0.0 2.8 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 KEY66651.1 - 2.2e-18 67.1 0.0 0.0017 18.2 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY66651.1 - 5.4e-17 62.0 0.0 9.1e-06 25.3 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY66651.1 - 1.1e-08 34.7 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY66651.1 - 3.8e-08 33.4 0.1 0.00059 19.8 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KEY66651.1 - 9e-08 32.9 0.5 0.00016 22.2 0.2 3.2 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 KEY66651.1 - 3e-07 30.5 0.0 0.003 17.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY66651.1 - 4.4e-07 30.3 0.0 0.0058 16.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KEY66651.1 - 3.9e-06 27.3 0.1 0.66 10.4 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEY66651.1 - 6.5e-06 26.5 0.1 0.061 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KEY66651.1 - 8.1e-06 26.0 0.0 0.0012 18.9 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 KEY66651.1 - 1.5e-05 25.1 0.0 0.25 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEY66651.1 - 1.6e-05 25.5 0.1 0.23 12.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KEY66651.1 - 1.6e-05 24.8 1.8 0.071 12.8 0.0 3.7 5 0 0 5 5 4 2 AAA ATPase domain AAA_16 PF13191.6 KEY66651.1 - 2.2e-05 24.9 1.1 0.42 11.0 0.0 4.2 4 1 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.22 KEY66651.1 - 2.2e-05 24.8 0.1 0.28 11.6 0.0 3.2 3 0 0 3 3 2 2 RNA helicase MeaB PF03308.16 KEY66651.1 - 6.4e-05 22.1 0.1 0.36 9.8 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KEY66651.1 - 0.00017 21.4 0.0 0.17 11.7 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 KEY66651.1 - 0.00026 20.7 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY66651.1 - 0.00027 20.9 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 KEY66651.1 - 0.0003 21.0 0.6 0.35 10.9 0.0 3.8 5 0 0 5 5 3 1 Helicase HerA, central domain AAA_24 PF13479.6 KEY66651.1 - 0.001 18.9 0.0 1.9 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KEY66651.1 - 0.0014 18.3 0.0 3.7 7.1 0.0 3.3 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEY66651.1 - 0.0014 18.4 0.0 3.1 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KEY66651.1 - 0.0015 18.5 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KEY66651.1 - 0.0016 18.5 0.0 5.4 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KEY66651.1 - 0.0019 17.4 0.1 1.4 8.0 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit Septin PF00735.18 KEY66651.1 - 0.0021 17.4 0.2 0.49 9.6 0.0 3.0 3 0 0 3 3 3 1 Septin NB-ARC PF00931.22 KEY66651.1 - 0.0043 16.3 0.4 0.34 10.0 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain Roc PF08477.13 KEY66651.1 - 0.0047 17.1 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 KEY66651.1 - 0.0048 16.7 0.0 0.8 9.5 0.0 2.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 KEY66651.1 - 0.0058 16.6 0.2 3.9 7.3 0.0 3.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 KEY66651.1 - 0.0062 16.7 0.0 1.7 8.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HEAT PF02985.22 KEY66651.1 - 0.0092 16.2 1.4 61 4.3 0.0 4.5 5 0 0 5 5 3 0 HEAT repeat ATP_bind_1 PF03029.17 KEY66651.1 - 0.0096 15.7 0.0 7.8 6.2 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT_2 PF13646.6 KEY66651.1 - 0.014 15.7 4.2 1.2 9.6 4.8 3.2 1 1 1 3 3 3 0 HEAT repeats PRK PF00485.18 KEY66651.1 - 0.016 15.0 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 KEY66651.1 - 0.017 14.9 0.0 5.7 6.6 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 KEY66651.1 - 0.018 14.7 0.0 6 6.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KEY66651.1 - 0.021 14.4 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KEY66651.1 - 0.03 13.9 0.0 2.9 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEY66651.1 - 0.032 14.1 0.0 9.2 6.1 0.0 3.0 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KEY66651.1 - 0.041 12.9 0.1 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein HEAT_EZ PF13513.6 KEY66651.1 - 0.05 14.1 5.0 29 5.3 0.0 5.5 6 1 1 7 7 4 0 HEAT-like repeat Cytidylate_kin PF02224.18 KEY66651.1 - 0.067 12.9 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase MukB PF04310.12 KEY66651.1 - 0.08 12.7 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Mg_chelatase PF01078.21 KEY66651.1 - 0.1 12.0 0.0 6.3 6.1 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KEY66651.1 - 0.1 11.7 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KEY66651.1 - 0.12 12.4 0.0 21 5.1 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KEY66651.1 - 0.85 8.2 7.6 2.7 6.5 0.0 3.8 5 0 0 5 5 5 0 AAA domain ADH_N_2 PF16884.5 KEY66652.1 - 1.2e-16 60.6 0.0 2.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY66652.1 - 4.3e-15 55.8 0.0 6.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY66652.1 - 1.6e-06 29.2 0.0 3.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_18 PF00704.28 KEY66652.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 18 bZIP_C PF12498.8 KEY66653.1 - 0.052 14.5 0.3 0.07 14.1 0.3 1.2 1 0 0 1 1 1 0 Basic leucine-zipper C terminal AA_permease PF00324.21 KEY66654.1 - 7.3e-100 334.8 44.8 9e-100 334.5 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY66654.1 - 2.6e-20 72.7 50.0 3.1e-20 72.4 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease TPR_8 PF13181.6 KEY66655.1 - 4.3e-09 35.9 0.5 0.36 11.2 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY66655.1 - 1.7e-08 33.9 2.1 0.73 10.1 1.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY66655.1 - 3.3e-08 33.0 0.9 0.06 13.2 0.7 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY66655.1 - 3.8e-06 27.3 0.2 0.21 12.1 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY66655.1 - 1e-05 25.7 8.3 0.024 14.9 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY66655.1 - 1.2e-05 25.9 2.5 3.5e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY66655.1 - 0.0009 19.9 11.3 0.78 10.7 0.0 5.4 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEY66655.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEY66655.1 - 0.0093 15.6 0.1 0.54 10.0 0.0 3.5 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 KEY66655.1 - 0.025 14.8 1.0 4.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KEY66655.1 - 0.08 12.3 0.7 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KEY66655.1 - 1.6 8.9 5.9 5.5 7.2 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat GYF PF02213.16 KEY66656.1 - 1.6e-18 66.1 0.2 4.5e-18 64.7 0.2 1.9 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KEY66656.1 - 0.013 15.3 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 GYF domain 2 DinB_2 PF12867.7 KEY66656.1 - 0.3 11.6 3.4 0.22 12.0 0.5 2.2 2 0 0 2 2 2 0 DinB superfamily UPF0086 PF01868.16 KEY66657.1 - 4.1e-29 100.3 0.1 4.1e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 KEY66658.1 - 4.1e-17 62.1 0.0 8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 KEY66659.1 - 1.7e-92 309.4 0.0 1.9e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DUF3134 PF11332.8 KEY66660.1 - 0.0034 17.7 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3134) WD40 PF00400.32 KEY66661.1 - 2.4e-11 44.0 5.5 0.11 13.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY66661.1 - 0.00021 21.5 0.7 0.14 12.5 0.1 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KEY66662.1 - 1.2e-41 142.8 31.9 1.2e-41 142.8 31.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY66662.1 - 2.6e-09 36.1 3.8 4.1e-09 35.4 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEY66662.1 - 1e-08 34.5 22.5 2.4e-08 33.3 22.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 KEY66664.1 - 2.2e-06 27.7 12.6 5.1e-06 26.5 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY66664.1 - 0.033 13.0 0.8 0.08 11.7 0.1 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain TPR_12 PF13424.6 KEY66665.1 - 0.00014 22.0 0.5 0.13 12.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY66665.1 - 0.00023 21.0 4.7 0.24 11.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY66665.1 - 0.00063 19.5 3.4 0.19 11.6 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY66665.1 - 0.038 14.5 1.4 0.038 14.5 1.4 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat KdpC PF02669.15 KEY66665.1 - 0.18 11.6 0.2 0.28 11.0 0.2 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain TPR_14 PF13428.6 KEY66665.1 - 0.39 11.7 13.5 1 10.4 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.6 KEY66666.1 - 3.6e-16 59.8 0.0 5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY66666.1 - 7.6e-09 36.2 0.0 5e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY66666.1 - 0.0094 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Pyr_redox_2 PF07992.14 KEY66667.1 - 2.6e-13 49.9 0.0 7.7e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY66667.1 - 0.00027 20.3 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY66667.1 - 0.00043 19.5 0.0 0.77 8.8 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEY66667.1 - 0.00067 19.7 1.3 0.82 9.7 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY66667.1 - 0.0017 17.1 0.0 0.013 14.2 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KEY66667.1 - 0.0022 18.2 0.1 0.0061 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEY66667.1 - 0.0041 16.3 0.1 0.036 13.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KEY66667.1 - 0.0086 15.2 0.1 0.044 12.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEY66667.1 - 0.052 13.1 0.3 0.096 12.2 0.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KEY66667.1 - 0.082 12.1 0.0 0.24 10.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FYVE PF01363.21 KEY66668.1 - 0.028 14.5 0.9 0.042 14.0 0.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger CTU2 PF10288.9 KEY66668.1 - 0.088 13.1 3.8 0.11 12.7 3.8 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 eIF3_subunit PF08597.10 KEY66668.1 - 1.1 9.2 17.8 1.2 9.0 17.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit HET PF06985.11 KEY66671.1 - 2.4e-36 125.3 0.0 2.1e-29 102.7 0.0 3.7 3 1 1 4 4 4 3 Heterokaryon incompatibility protein (HET) Glyco_hydro_49N PF17433.2 KEY66671.1 - 0.09 12.4 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Oxidored_FMN PF00724.20 KEY66673.1 - 6.1e-40 137.5 0.0 8.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KEY66673.1 - 0.00044 19.4 0.2 0.00097 18.3 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 KEY66673.1 - 0.033 13.6 0.9 0.051 13.0 0.9 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Glyco_hydro_64 PF16483.5 KEY66674.1 - 1.7e-108 363.2 0.0 2e-108 363.0 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Dynamin_N PF00350.23 KEY66675.1 - 2.8e-14 53.5 0.0 8.5e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KEY66675.1 - 1.2e-07 31.8 0.0 0.00029 20.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY66675.1 - 4.2e-06 26.8 0.1 3.4e-05 23.8 0.0 2.5 2 1 1 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KEY66675.1 - 0.00048 20.7 0.0 0.0025 18.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KEY66675.1 - 0.0011 19.4 0.1 0.0052 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF4806 PF16064.5 KEY66675.1 - 0.0048 17.2 0.4 0.26 11.6 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4806) FeoB_N PF02421.18 KEY66675.1 - 0.029 13.9 0.0 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KEY66675.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KEY66675.1 - 0.071 12.4 0.0 0.59 9.4 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 KEY66675.1 - 0.12 12.6 0.2 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain GLTP PF08718.11 KEY66675.1 - 6.7 7.0 6.5 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Glycolipid transfer protein (GLTP) Fungal_trans PF04082.18 KEY66677.1 - 9.1e-09 34.7 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66677.1 - 7.9e-06 25.9 7.2 1.6e-05 24.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 KEY66679.1 - 7.2e-52 176.3 0.0 8.5e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.7 KEY66680.1 - 6e-80 263.9 0.8 4.6e-15 56.0 0.1 9.7 1 1 10 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY66680.1 - 4.2e-52 173.9 7.5 1.5e-05 25.5 0.0 11.9 8 3 3 11 11 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66680.1 - 1.1e-48 157.5 14.0 3.3e-05 24.0 0.0 17.8 18 0 0 18 18 18 9 Ankyrin repeat Ank_5 PF13857.6 KEY66680.1 - 8.9e-42 140.6 17.8 9.6e-08 32.2 0.2 12.9 3 3 10 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.30 KEY66680.1 - 3.6e-36 122.1 18.1 0.00058 20.2 0.0 13.9 14 1 0 14 14 12 7 Ankyrin repeat NACHT PF05729.12 KEY66680.1 - 4.9e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY66680.1 - 2e-06 28.3 0.0 2e-06 28.3 0.0 3.0 4 0 0 4 4 3 1 AAA ATPase domain DUF676 PF05057.14 KEY66680.1 - 1.5e-05 24.6 0.1 4.5e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 KEY66680.1 - 0.00024 21.4 0.0 0.00077 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Cutinase PF01083.22 KEY66680.1 - 0.0038 17.2 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 KEY66680.1 - 0.0041 17.7 0.1 0.022 15.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEY66680.1 - 0.0074 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KEY66680.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase AAA_19 PF13245.6 KEY66680.1 - 0.0094 16.3 0.0 0.034 14.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Docking PF08990.11 KEY66680.1 - 0.024 14.2 0.3 0.06 13.0 0.3 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking KAP_NTPase PF07693.14 KEY66680.1 - 0.027 13.7 5.3 0.39 9.9 0.1 3.3 2 1 0 3 3 3 0 KAP family P-loop domain LCAT PF02450.15 KEY66680.1 - 0.045 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ATPase_2 PF01637.18 KEY66680.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KEY66680.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ZZ PF00569.17 KEY66680.1 - 0.078 12.8 9.8 0.07 12.9 7.9 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type ABC_tran PF00005.27 KEY66680.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KEY66680.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KEY66680.1 - 0.34 11.5 1.7 0.84 10.2 0.0 2.6 3 0 0 3 3 1 0 AAA domain SDA1 PF05285.12 KEY66680.1 - 1.4 8.2 19.4 0.3 10.5 0.9 2.3 2 0 0 2 2 2 0 SDA1 NAD_binding_2 PF03446.15 KEY66681.1 - 8.4e-24 84.5 0.4 1.3e-23 83.9 0.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEY66681.1 - 8.9e-09 35.6 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KEY66681.1 - 2.7e-06 27.9 0.0 7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEY66681.1 - 0.032 14.3 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2CSK_N PF08521.10 KEY66681.1 - 0.037 14.1 0.9 0.083 13.0 0.9 1.6 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal DUF4139 PF13598.6 KEY66682.1 - 6.6e-34 117.4 0.7 5.6e-33 114.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KEY66682.1 - 2.7e-25 88.6 0.0 2.7e-25 88.6 0.0 3.2 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) LPP PF04728.13 KEY66682.1 - 1.9 8.9 10.9 0.96 9.9 0.6 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper XhlA PF10779.9 KEY66684.1 - 0.023 14.9 0.3 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Haemolysin XhlA CCDC154 PF15450.6 KEY66684.1 - 0.39 9.2 2.5 0.71 8.4 0.6 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Methyltransf_10 PF05971.12 KEY66685.1 - 2.6e-63 214.1 0.0 3.5e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KEY66685.1 - 9.4e-05 22.0 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KEY66685.1 - 0.041 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KEY66685.1 - 0.058 12.8 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF218 PF02698.17 KEY66686.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain adh_short_C2 PF13561.6 KEY66687.1 - 4.4e-60 203.1 0.2 5.9e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66687.1 - 5.6e-43 146.7 0.5 9.7e-43 145.9 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66687.1 - 9e-15 55.0 0.7 1.2e-14 54.6 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66687.1 - 1.6e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY66687.1 - 6.6e-05 22.0 0.2 9e-05 21.6 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY66687.1 - 8e-05 22.2 0.0 0.0001 21.8 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY66687.1 - 0.00026 20.3 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEY66687.1 - 0.00054 19.9 0.1 0.00083 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEY66687.1 - 0.04 14.2 0.1 0.089 13.1 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KEY66687.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEY66687.1 - 0.11 13.1 0.1 0.32 11.7 0.1 1.8 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 KEY66687.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family ThiF PF00899.21 KEY66687.1 - 0.36 10.1 1.6 0.79 9.0 0.3 2.0 1 1 2 3 3 3 0 ThiF family GST_N_3 PF13417.6 KEY66688.1 - 1.9e-21 76.2 0.0 4.8e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY66688.1 - 7.1e-19 67.9 0.0 3.1e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY66688.1 - 5.1e-09 36.4 0.0 8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY66688.1 - 1.9e-07 31.0 0.3 3.4e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY66688.1 - 0.00028 21.0 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY66688.1 - 0.017 15.7 0.0 0.03 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY66688.1 - 0.05 13.8 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain XAP5 PF04921.14 KEY66689.1 - 1.3e-93 313.5 0.0 1.7e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KEY66689.1 - 0.00048 20.6 1.3 0.00048 20.6 1.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4604) JAKMIP_CC3 PF16034.5 KEY66689.1 - 0.0018 18.3 0.4 0.0033 17.4 0.4 1.4 1 0 0 1 1 1 1 JAKMIP CC3 domain Peptidase_U4 PF03419.13 KEY66690.1 - 0.54 9.5 9.6 0.69 9.1 9.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2165 PF09933.9 KEY66690.1 - 1.8 8.6 9.6 3.7 7.6 9.4 1.7 1 1 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) AAA_10 PF12846.7 KEY66691.1 - 0.065 12.2 0.0 3.3 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 KEY66691.1 - 0.068 13.4 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEY66691.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KEY66691.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_3_C PF01915.22 KEY66692.1 - 3.5e-43 147.9 0.0 1.3e-42 146.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY66692.1 - 3.7e-34 118.5 0.0 7.4e-34 117.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY66692.1 - 3.1e-22 78.5 0.1 6e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_2_N PF02837.18 KEY66693.1 - 3.1e-14 53.2 0.4 1.8e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KEY66693.1 - 2.1e-09 36.9 0.5 4.2e-08 32.7 0.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KEY66693.1 - 2.1e-06 28.4 0.0 5.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KEY66693.1 - 0.099 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain AltA1 PF16541.5 KEY66695.1 - 2.7e-23 83.0 0.7 3.6e-23 82.5 0.7 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 P22_Tail-4 PF11650.8 KEY66695.1 - 0.21 11.5 0.0 1.3 8.9 0.0 1.9 1 1 0 1 1 1 0 P22 tail accessory factor BTB PF00651.31 KEY66697.1 - 5.8e-06 26.5 0.0 2.6e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Phage_int_SAM_4 PF13495.6 KEY66697.1 - 0.12 12.9 0.4 0.35 11.4 0.4 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Fungal_trans_2 PF11951.8 KEY66699.1 - 2.9e-39 135.0 4.8 3.5e-39 134.7 4.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 KEY66700.1 - 1.9e-19 70.8 0.0 2.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KEY66700.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease PF00324.21 KEY66701.1 - 3.6e-108 362.2 41.9 4.4e-108 361.9 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY66701.1 - 7.3e-31 107.4 46.3 9.4e-31 107.1 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease MscL PF01741.18 KEY66701.1 - 2.1 8.7 5.8 10 6.4 0.0 3.1 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Aminotran_1_2 PF00155.21 KEY66702.1 - 3e-26 92.5 0.0 4.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL_2 PF13472.6 KEY66703.1 - 6.9e-13 49.4 0.1 1.1e-12 48.8 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 KEY66703.1 - 3.1e-10 39.8 15.3 6.5e-10 38.8 15.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KEY66703.1 - 1.3e-06 28.5 0.0 4.8e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Toxin_7 PF05980.12 KEY66703.1 - 0.23 11.7 8.0 0.5 10.6 8.0 1.6 1 0 0 1 1 1 0 Toxin 7 Zn_clus PF00172.18 KEY66704.1 - 3.4e-06 27.1 5.6 3.4e-06 27.1 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY66705.1 - 3e-35 121.5 0.0 3.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66705.1 - 6.1e-28 98.0 0.0 3.3e-26 92.3 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66705.1 - 1.3e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY66705.1 - 2.3e-08 33.5 0.0 3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEY66705.1 - 6.9e-05 22.4 0.1 0.00027 20.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CotH PF08757.11 KEY66705.1 - 0.17 11.4 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 CotH kinase protein HAD_2 PF13419.6 KEY66707.1 - 3.2e-14 53.4 0.0 4.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY66707.1 - 3.3e-05 23.9 0.0 7.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY66707.1 - 0.0014 19.0 0.0 0.0029 17.9 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 KEY66708.1 - 4.9e-68 229.5 0.0 5.6e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GTP_EFTU PF00009.27 KEY66709.1 - 1.6e-49 168.1 0.0 2.4e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KEY66709.1 - 3.2e-36 123.7 2.6 5.9e-36 122.9 2.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KEY66709.1 - 1.7e-12 47.2 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY66709.1 - 1.4e-06 28.6 0.1 3.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY66709.1 - 1.8e-05 24.8 0.2 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KEY66709.1 - 3.9e-05 23.3 0.0 0.0048 16.5 0.0 2.3 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 KEY66709.1 - 0.0015 18.6 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KEY66709.1 - 0.015 14.8 0.0 0.056 12.9 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 KEY66709.1 - 0.042 14.1 0.0 0.79 10.0 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RF3_C PF16658.5 KEY66709.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KEY66709.1 - 0.2 11.9 2.4 0.41 10.9 2.4 1.4 1 0 0 1 1 1 0 Snurportin1 Glyco_hydro_61 PF03443.14 KEY66710.1 - 1.4e-39 136.2 0.0 1.7e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SRAP PF02586.14 KEY66711.1 - 3.4e-77 258.9 0.0 6.3e-77 258.0 0.0 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) DDHD PF02862.17 KEY66712.1 - 7.9e-61 206.1 1.8 2.9e-59 201.0 0.0 2.9 3 0 0 3 3 3 1 DDHD domain LIDHydrolase PF10230.9 KEY66712.1 - 0.2 11.2 0.0 0.47 10.0 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase CH PF00307.31 KEY66714.1 - 3.2e-69 230.0 0.0 3.5e-18 65.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KEY66714.1 - 1.5e-06 28.5 0.4 2.4e-05 24.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEY66714.1 - 0.043 13.4 0.3 21 5.0 0.1 3.5 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KEY66714.1 - 0.13 12.3 1.8 3.1 8.0 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain RRM_1 PF00076.22 KEY66715.1 - 4e-08 33.0 0.0 3.6e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY66715.1 - 0.083 12.9 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 KEY66716.1 - 5.7e-76 250.6 1.1 8.4e-25 86.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY66716.1 - 9.7e-06 24.9 0.1 0.0025 17.0 0.0 2.9 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 KEY66717.1 - 1.8e-91 304.7 4.1 2e-91 304.5 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KEY66717.1 - 0.019 15.6 0.3 0.019 15.6 0.3 2.1 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A FtsJ PF01728.19 KEY66718.1 - 4.5e-43 147.4 0.0 1.2e-41 142.7 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KEY66718.1 - 0.0002 21.2 0.0 0.00066 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66718.1 - 0.011 15.6 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Spc7 PF08317.11 KEY66719.1 - 0.045 12.6 48.1 0.39 9.5 26.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 KEY66719.1 - 0.21 11.1 43.1 0.036 13.7 13.7 3.6 1 1 2 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KEY66719.1 - 0.29 11.1 11.4 0.78 9.8 2.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KEY66719.1 - 0.49 7.8 41.9 0.81 7.1 41.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC144C PF14915.6 KEY66719.1 - 0.53 9.4 45.8 0.14 11.3 38.6 3.5 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region GAS PF13851.6 KEY66719.1 - 2.3 7.5 51.2 0.71 9.2 22.2 3.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KEY66719.1 - 5.8 7.3 43.2 0.77 10.1 0.9 6.6 1 1 5 6 6 6 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 KEY66719.1 - 6 6.2 52.9 0.091 12.2 30.1 2.6 2 1 1 3 3 3 0 Golgin subfamily A member 5 DASH_Hsk3 PF08227.11 KEY66719.1 - 9.3 6.7 11.8 27 5.2 0.3 4.1 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like OST3_OST6 PF04756.13 KEY66720.1 - 5.7e-106 354.1 0.0 7.1e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family VKOR PF07884.14 KEY66720.1 - 0.032 14.4 1.6 0.032 14.4 1.6 1.7 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Thioredoxin PF00085.20 KEY66720.1 - 0.085 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin MerC PF03203.14 KEY66720.1 - 0.09 13.2 5.5 0.33 11.4 0.1 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein DUF3169 PF11368.8 KEY66720.1 - 0.36 10.3 6.0 1.6 8.2 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) CPBP PF02517.16 KEY66720.1 - 1.8 9.0 5.6 15 6.1 5.5 2.2 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease HXXEE PF13787.6 KEY66720.1 - 3.6 8.4 6.4 0.71 10.7 1.7 2.0 1 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Glyco_hydro_6 PF01341.17 KEY66721.1 - 1.7e-95 320.3 0.2 2.1e-95 320.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 WD40 PF00400.32 KEY66722.1 - 5.6e-45 150.4 25.3 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY66722.1 - 1.4e-09 38.2 0.5 0.059 13.7 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY66722.1 - 9.7e-06 24.5 6.8 0.062 11.9 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEY66722.1 - 0.0025 16.8 0.1 9.1 5.1 0.0 4.0 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY66722.1 - 0.005 16.2 0.0 0.31 10.3 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KEY66722.1 - 0.031 14.2 1.2 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Glyco_hydro_15 PF00723.21 KEY66723.1 - 3.2e-91 306.4 0.1 3.9e-91 306.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KEY66723.1 - 1.5e-28 98.5 0.0 3e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain DHH PF01368.20 KEY66724.1 - 0.0014 18.9 0.2 0.0023 18.1 0.2 1.4 1 0 0 1 1 1 1 DHH family Fungal_trans PF04082.18 KEY66726.1 - 4.8e-25 88.1 0.9 6.9e-25 87.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.6 KEY66727.1 - 1.8e-41 142.1 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEY66727.1 - 1.2e-09 38.4 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 KEY66727.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Beta-galactosidase adh_short_C2 PF13561.6 KEY66728.1 - 4.6e-53 180.2 0.0 6.4e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY66728.1 - 1.9e-42 144.9 0.3 2.5e-42 144.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY66728.1 - 8e-11 42.2 0.7 1.1e-10 41.7 0.7 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY66728.1 - 0.057 12.6 0.1 0.091 11.9 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RuBisCO_large PF00016.20 KEY66728.1 - 0.51 9.5 2.9 0.27 10.4 0.7 1.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Hydrolase_6 PF13344.6 KEY66729.1 - 7.3e-22 77.4 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY66729.1 - 1.4e-12 47.5 0.0 6.5e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY66729.1 - 0.1 12.8 0.0 32 4.7 0.0 2.9 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase DUF456 PF04306.13 KEY66730.1 - 0.037 14.3 4.1 0.064 13.5 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Mitochondr_Som1 PF11093.8 KEY66731.1 - 6.9e-10 38.8 0.0 8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Ribosomal_L22 PF00237.19 KEY66733.1 - 2.5e-19 69.4 0.0 4.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CFEM PF05730.11 KEY66734.1 - 2.1e-08 34.1 9.4 3.4e-08 33.5 9.4 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KEY66734.1 - 1.4e-06 27.6 1.9 1.4e-06 27.6 1.9 1.7 2 0 0 2 2 1 1 Transmembrane alpha-helix domain CbtA PF09490.10 KEY66734.1 - 0.0021 17.9 0.0 0.006 16.4 0.0 1.8 1 1 1 2 2 2 1 Probable cobalt transporter subunit (CbtA) TMEM154 PF15102.6 KEY66734.1 - 0.011 15.7 3.7 0.025 14.5 0.0 2.3 1 1 1 2 2 2 0 TMEM154 protein family DUF4448 PF14610.6 KEY66734.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LapA_dom PF06305.11 KEY66734.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Plasmodium_Vir PF05795.11 KEY66734.1 - 0.079 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Podoplanin PF05808.11 KEY66734.1 - 0.089 12.9 7.5 0.066 13.3 4.4 2.0 1 1 1 2 2 2 0 Podoplanin Ndc1_Nup PF09531.10 KEY66734.1 - 1.2 7.7 4.6 1.4 7.5 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KEY66734.1 - 2.7 7.8 8.5 3.4 7.5 8.5 1.2 1 0 0 1 1 1 0 SPX domain CDC27 PF09507.10 KEY66734.1 - 3 7.1 13.4 4 6.7 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.22 KEY66735.1 - 1.1e-48 162.8 0.1 1.2e-16 60.2 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY66735.1 - 2.6e-29 100.9 0.0 7.6e-26 89.8 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KEY66735.1 - 1.6e-08 34.2 0.0 2.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY66735.1 - 7.8e-08 32.2 0.0 0.014 15.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KEY66735.1 - 5.5e-05 23.1 0.0 0.0017 18.2 0.0 2.9 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEY66735.1 - 0.00057 19.9 0.2 0.17 11.9 0.0 2.9 2 0 0 2 2 2 1 RNA binding motif RL PF17797.1 KEY66735.1 - 0.018 15.0 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 KEY66735.1 - 0.054 13.6 0.0 4.4 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif HA2 PF04408.23 KEY66736.1 - 1.4e-15 57.4 1.9 2.4e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEY66736.1 - 9.8e-14 51.6 0.0 2.6e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY66736.1 - 2e-11 44.0 0.0 4.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY66736.1 - 6.1e-08 33.0 0.4 7.9e-07 29.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 KEY66736.1 - 1.7e-07 31.5 0.0 5.5e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KEY66736.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEY66736.1 - 0.049 14.2 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 KEY66736.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KEY66736.1 - 6.2 7.3 0.0 6.2 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Gcn1_N PF12074.8 KEY66737.1 - 1e-110 370.4 5.5 1e-110 370.4 5.5 3.5 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KEY66737.1 - 3.2e-60 202.4 8.3 7.3e-60 201.2 8.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KEY66737.1 - 1.1e-36 121.6 31.5 0.016 15.4 0.1 20.9 22 0 0 22 22 19 9 HEAT repeat HEAT_EZ PF13513.6 KEY66737.1 - 4.8e-31 106.8 52.5 1.3e-07 31.9 0.1 20.8 17 4 8 25 25 21 6 HEAT-like repeat HEAT_2 PF13646.6 KEY66737.1 - 3.5e-26 91.4 54.5 3.2e-06 27.5 0.0 15.7 11 4 10 21 21 20 10 HEAT repeats Vac14_Fab1_bd PF12755.7 KEY66737.1 - 4.3e-15 56.1 0.0 0.23 12.1 0.0 9.0 8 1 1 9 9 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEY66737.1 - 1.6e-14 54.2 12.7 0.37 10.8 0.2 12.5 9 3 4 13 13 13 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KEY66737.1 - 3.1e-11 43.7 2.4 4.1e-05 23.8 0.0 6.2 6 1 1 7 7 6 1 Parkin co-regulated protein CLASP_N PF12348.8 KEY66737.1 - 1.2e-10 41.3 0.0 0.045 13.3 0.0 6.5 7 1 2 9 9 9 3 CLASP N terminal Adaptin_N PF01602.20 KEY66737.1 - 2e-08 33.3 10.2 0.0033 16.1 0.7 6.7 5 3 1 6 6 6 3 Adaptin N terminal region Ecm29 PF13001.7 KEY66737.1 - 5.8e-06 25.3 5.3 0.11 11.1 0.1 5.7 5 1 0 5 5 5 1 Proteasome stabiliser TIP120 PF08623.10 KEY66737.1 - 4.6e-05 23.3 0.0 0.048 13.4 0.0 5.4 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 KEY66737.1 - 0.0004 20.3 0.1 2.8 7.8 0.0 6.0 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KEY66737.1 - 0.00068 19.3 6.6 17 4.8 0.0 7.5 6 2 2 9 9 9 0 Tti2 family MMS19_C PF12460.8 KEY66737.1 - 0.0015 17.8 13.9 0.045 12.9 0.0 6.6 6 2 2 8 8 8 1 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.6 KEY66737.1 - 0.0015 18.9 0.3 1.3 9.5 0.0 5.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain FANCI_S2 PF14676.6 KEY66737.1 - 0.0018 18.6 2.8 1.3 9.3 0.1 5.3 4 1 1 5 5 5 1 FANCI solenoid 2 Vitellogenin_N PF01347.22 KEY66737.1 - 0.033 12.6 0.5 2.3 6.5 0.0 3.8 5 0 0 5 5 5 0 Lipoprotein amino terminal region Ipi1_N PF12333.8 KEY66737.1 - 0.077 13.6 1.2 1.3 9.6 0.1 3.9 4 0 0 4 4 2 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.23 KEY66737.1 - 0.15 12.1 10.3 1.2e+02 2.9 0.0 9.1 10 1 1 11 11 8 0 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 KEY66737.1 - 0.16 11.8 6.3 0.22 11.3 0.0 4.1 4 2 0 4 4 3 0 Tubulin folding cofactor D C terminal Dopey_N PF04118.14 KEY66737.1 - 0.2 10.7 1.4 21 4.1 0.0 4.7 4 2 1 5 5 5 0 Dopey, N-terminal RIX1 PF08167.12 KEY66737.1 - 0.66 9.7 8.7 0.095 12.4 0.3 4.0 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis U3snoRNP10 PF12397.8 KEY66737.1 - 9.3 6.6 12.8 35 4.8 0.0 6.8 7 0 0 7 7 6 0 U3 small nucleolar RNA-associated protein 10 SHMT PF00464.19 KEY66738.1 - 9.6e-197 653.4 0.0 1.1e-196 653.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase 2OG-FeII_Oxy_2 PF13532.6 KEY66739.1 - 3.3e-28 99.2 0.0 7.1e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KEY66739.1 - 2e-27 96.5 1.7 3e-27 95.9 0.1 2.1 2 1 0 2 2 2 1 Isochorismatase family GST_C_2 PF13410.6 KEY66739.1 - 0.00026 21.0 0.1 0.00066 19.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF966 PF06136.13 KEY66739.1 - 0.84 9.3 5.2 5.1 6.7 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) TAF8_C PF10406.9 KEY66740.1 - 1.5e-18 67.1 1.7 2.2e-18 66.5 0.3 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KEY66740.1 - 7.8e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF4 PF05236.14 KEY66740.1 - 0.0062 16.3 4.3 0.011 15.5 4.3 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.24 KEY66740.1 - 0.016 15.5 0.1 0.016 15.5 0.1 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF4798 PF16055.5 KEY66740.1 - 0.077 13.2 1.9 0.18 12.1 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Viral_alk_exo PF01771.17 KEY66740.1 - 0.084 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral alkaline exonuclease GST_C_2 PF13410.6 KEY66741.1 - 5.1e-10 39.2 0.6 1e-09 38.3 0.6 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY66741.1 - 1.1e-06 28.9 0.0 2.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY66741.1 - 1.4e-06 28.4 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY66741.1 - 2.5e-06 27.6 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEY66741.1 - 1.1e-05 25.7 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KEY66741.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEY66741.1 - 0.15 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short PF00106.25 KEY66743.1 - 6.2e-27 94.3 0.5 2.7e-25 89.0 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66743.1 - 2.2e-17 63.4 1.1 2.7e-16 59.8 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66743.1 - 1.8e-08 34.5 0.3 2.7e-08 34.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY66743.1 - 0.0028 17.9 0.0 0.01 16.1 0.1 1.9 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KEY66743.1 - 0.023 14.7 0.0 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KEY66743.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDE_Tnp_Tn3 PF01526.17 KEY66743.1 - 0.057 12.2 0.2 0.69 8.6 0.1 2.0 1 1 1 2 2 2 0 Tn3 transposase DDE domain Alpha-amylase PF00128.24 KEY66744.1 - 7.3e-110 367.7 0.0 1.1e-109 367.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KEY66744.1 - 0.0045 16.1 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDPD PF03009.17 KEY66744.1 - 0.08 12.7 0.2 8.3 6.0 0.1 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Malt_amylase_C PF16657.5 KEY66744.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Sugar_tr PF00083.24 KEY66745.1 - 6.7e-85 285.6 16.3 7.8e-85 285.4 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66745.1 - 2.5e-20 72.7 26.9 1.1e-17 64.1 19.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY66745.1 - 1.3e-05 23.9 18.1 0.0012 17.5 1.5 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein Zn_clus PF00172.18 KEY66746.1 - 1.4 9.1 16.4 0.15 12.2 11.9 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4 PF00097.25 KEY66747.1 - 5.4e-08 32.6 5.2 9.4e-08 31.8 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY66747.1 - 6.6e-07 29.2 1.9 6.6e-07 29.2 1.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY66747.1 - 7e-07 29.0 3.6 1.4e-06 28.1 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY66747.1 - 3.6e-06 26.8 3.5 6.8e-06 26.0 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEY66747.1 - 3.7e-06 27.2 5.4 6.7e-06 26.3 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEY66747.1 - 9.5e-06 25.4 5.1 1.7e-05 24.6 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY66747.1 - 5e-05 23.4 5.1 0.00035 20.7 5.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEY66747.1 - 0.0059 16.4 7.4 0.034 14.0 7.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 ChW PF07538.11 KEY66747.1 - 0.073 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Clostridial hydrophobic W zf-rbx1 PF12678.7 KEY66747.1 - 0.13 12.6 4.1 0.35 11.2 4.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KEY66747.1 - 0.22 11.6 1.4 0.29 11.2 0.3 1.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-MIZ PF02891.20 KEY66747.1 - 0.33 10.7 4.3 1.5 8.6 4.4 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_10 PF16685.5 KEY66747.1 - 0.45 10.7 4.7 1 9.6 4.7 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 KEY66747.1 - 3.2 7.3 4.4 5.5 6.5 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain AMPK1_CBM PF16561.5 KEY66748.1 - 9.9e-20 70.6 0.3 1.8e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KEY66748.1 - 0.048 14.0 0.2 0.097 13.0 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KEY66748.1 - 0.067 13.8 0.2 0.15 12.6 0.2 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Glyco_hydro_114 PF03537.13 KEY66750.1 - 2.2e-83 279.1 0.1 2.6e-83 278.9 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SPOC PF07744.13 KEY66751.1 - 1e-24 87.2 0.0 2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KEY66751.1 - 1.5e-19 70.5 1.8 4.3e-19 69.0 1.8 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KEY66751.1 - 1.5e-08 34.4 9.4 2.6e-08 33.6 9.4 1.4 1 0 0 1 1 1 1 PHD-finger Med7 PF05983.11 KEY66752.1 - 3.8e-62 209.8 0.6 4.5e-62 209.5 0.6 1.1 1 0 0 1 1 1 1 MED7 protein CENP-Q PF13094.6 KEY66753.1 - 0.013 15.7 10.2 0.013 15.7 10.2 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-met PF12874.7 KEY66753.1 - 0.022 15.2 0.3 0.038 14.4 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KEY66753.1 - 0.025 14.9 0.1 0.046 14.1 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEY66753.1 - 0.028 14.7 0.2 0.052 13.8 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Cep57_CLD_2 PF14197.6 KEY66753.1 - 0.084 13.0 9.8 0.23 11.6 9.8 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AKAP95 PF04988.12 KEY66753.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) FAM76 PF16046.5 KEY66753.1 - 0.31 10.3 7.7 0.12 11.7 1.6 2.1 2 0 0 2 2 2 0 FAM76 protein PCRF PF03462.18 KEY66753.1 - 2.9 7.7 12.1 0.058 13.2 4.1 2.0 2 0 0 2 2 2 0 PCRF domain UPF0449 PF15136.6 KEY66753.1 - 3.7 8.1 9.9 0.13 12.8 1.3 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 TFIIA PF03153.13 KEY66753.1 - 6 6.7 27.6 11 5.9 27.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.33 KEY66754.1 - 3.7e-09 36.2 2.7 1.5e-08 34.3 0.1 2.5 2 0 0 2 2 2 1 F-box domain RPEL PF02755.15 KEY66754.1 - 5.2e-07 29.2 0.0 0.0005 19.7 0.0 2.8 2 0 0 2 2 2 2 RPEL repeat F-box-like PF12937.7 KEY66754.1 - 8.1e-07 28.8 0.3 8.1e-07 28.8 0.3 2.7 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KEY66754.1 - 0.0017 18.2 0.1 0.0017 18.2 0.1 2.0 2 0 0 2 2 2 1 F-box LAMTOR PF15454.6 KEY66756.1 - 8.6e-08 32.7 0.0 1.5e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3197 PF11432.8 KEY66756.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) FAM184 PF15665.5 KEY66759.1 - 0.00039 20.3 14.3 0.0029 17.4 7.5 2.0 2 0 0 2 2 2 2 Family with sequence similarity 184, A and B HSBP1 PF06825.12 KEY66759.1 - 0.0064 16.3 5.8 0.11 12.3 0.3 3.1 4 0 0 4 4 4 1 Heat shock factor binding protein 1 Vac_Fusion PF02346.16 KEY66759.1 - 0.019 14.6 2.1 2.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 NCD2 PF04905.13 KEY66759.1 - 0.023 14.7 0.7 0.038 13.9 0.7 1.3 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) bZIP_1 PF00170.21 KEY66759.1 - 0.029 14.5 0.5 0.029 14.5 0.5 2.8 3 0 0 3 3 2 0 bZIP transcription factor ABC_tran_CTD PF16326.5 KEY66759.1 - 0.033 14.4 17.1 0.11 12.7 0.7 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4164 PF13747.6 KEY66759.1 - 0.035 14.4 9.8 0.31 11.3 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) GST_C_2 PF13410.6 KEY66759.1 - 0.038 14.0 0.8 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Spectrin PF00435.21 KEY66759.1 - 0.04 14.4 14.8 1.1 9.8 1.3 3.2 2 1 1 3 3 3 0 Spectrin repeat Alpha-mann_mid PF09261.11 KEY66759.1 - 0.045 13.9 0.7 0.045 13.9 0.7 2.4 2 1 0 2 2 2 0 Alpha mannosidase middle domain Prefoldin_2 PF01920.20 KEY66759.1 - 0.1 12.6 12.2 0.13 12.3 0.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit Rx_N PF18052.1 KEY66759.1 - 0.21 11.9 7.6 0.89 9.9 3.8 2.7 2 1 0 2 2 2 0 Rx N-terminal domain TMF_DNA_bd PF12329.8 KEY66759.1 - 0.21 11.6 15.7 1.7 8.7 3.7 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 KEY66759.1 - 0.28 11.7 12.3 0.33 11.5 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 KEY66759.1 - 0.4 9.7 9.3 0.87 8.6 9.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HSCB_C PF07743.13 KEY66759.1 - 0.49 10.9 14.9 3.8 8.1 0.7 2.9 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain EMP24_GP25L PF01105.24 KEY66759.1 - 0.49 10.3 6.3 3.4 7.6 3.6 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 KEY66759.1 - 0.51 10.8 7.3 4.5 7.8 1.0 2.8 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KEY66759.1 - 0.55 10.8 9.8 6.7 7.3 5.5 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 KEY66759.1 - 0.56 10.3 16.9 17 5.5 7.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.6 KEY66759.1 - 1.1 9.7 6.4 1.8 9.0 6.4 1.3 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KEY66759.1 - 1.4 8.2 14.5 8.3 5.7 14.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KEY66759.1 - 2 8.5 15.0 12 6.0 0.0 2.4 2 1 0 2 2 2 0 FlxA-like protein XhlA PF10779.9 KEY66759.1 - 2 8.7 14.4 3.1 8.1 0.3 3.4 2 1 0 3 3 3 0 Haemolysin XhlA Ax_dynein_light PF10211.9 KEY66759.1 - 2.2 8.2 14.9 5.6 6.9 2.1 3.0 2 1 1 3 3 3 0 Axonemal dynein light chain CLZ PF16526.5 KEY66759.1 - 3.2 8.2 11.5 1.4 9.4 0.4 2.9 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Swi5 PF07061.11 KEY66759.1 - 3.4 7.8 12.3 1.7 8.8 2.5 3.0 2 1 1 3 3 3 0 Swi5 Fib_alpha PF08702.10 KEY66759.1 - 8.4 6.6 12.4 5.8 7.1 1.6 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-F_N PF10481.9 KEY66761.1 - 0.0026 17.5 0.7 0.16 11.6 0.1 2.1 2 0 0 2 2 2 1 Cenp-F N-terminal domain Herpes_UL6 PF01763.16 KEY66761.1 - 0.0026 16.4 1.2 0.0027 16.3 0.3 1.4 2 0 0 2 2 2 1 Herpesvirus UL6 like Med4 PF10018.9 KEY66761.1 - 0.0039 16.9 1.6 0.0049 16.6 0.2 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.8 KEY66761.1 - 0.014 15.4 1.7 1 9.4 0.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KEY66761.1 - 0.035 13.5 3.3 0.059 12.7 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 KEY66761.1 - 0.035 14.0 0.1 7.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit SKA1 PF07160.12 KEY66761.1 - 0.055 13.3 0.3 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TMF_TATA_bd PF12325.8 KEY66761.1 - 0.063 13.5 0.2 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HTH_34 PF13601.6 KEY66761.1 - 0.086 13.0 0.3 7.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain Fib_alpha PF08702.10 KEY66761.1 - 0.088 13.0 0.3 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KEY66761.1 - 0.13 12.7 4.2 0.45 10.9 4.2 1.8 1 1 0 1 1 1 0 Fez1 Uso1_p115_C PF04871.13 KEY66761.1 - 0.16 12.3 3.2 1.3 9.4 0.2 2.5 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 KEY66761.1 - 2.5 8.3 7.0 6.1 7.0 0.0 3.2 3 0 0 3 3 3 0 bZIP transcription factor Haem_degrading PF03928.14 KEY66762.1 - 1.1e-33 115.8 0.2 1.3e-33 115.5 0.2 1.1 1 0 0 1 1 1 1 Haem-degrading Sugar_tr PF00083.24 KEY66763.1 - 1.2e-83 281.4 16.8 1.5e-83 281.2 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY66763.1 - 3.3e-27 95.3 19.2 4.6e-27 94.9 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY66763.1 - 2.4e-06 26.3 7.3 1.5e-05 23.7 2.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEY66763.1 - 0.00091 17.9 1.1 0.00091 17.9 1.1 2.7 3 1 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KEY66763.1 - 2.5 6.3 19.5 0.073 11.3 2.4 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CDP-OH_P_transf PF01066.21 KEY66763.1 - 3.2 8.6 5.2 43 5.0 0.7 3.3 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Nuc_sug_transp PF04142.15 KEY66765.1 - 5.2e-100 334.7 7.0 7e-100 334.2 7.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KEY66765.1 - 5.7e-07 29.8 27.0 2.1e-06 27.9 6.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KEY66765.1 - 0.0007 18.9 18.5 0.029 13.6 7.7 2.7 2 1 0 2 2 2 2 UAA transporter family DUF2427 PF10348.9 KEY66765.1 - 0.3 10.9 5.2 9.5 6.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) TPT PF03151.16 KEY66765.1 - 1.4 8.2 14.8 0.34 10.2 2.5 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family TMEM234 PF10639.9 KEY66765.1 - 1.7 8.7 13.7 0.65 10.0 2.1 2.9 3 0 0 3 3 3 0 Putative transmembrane family 234 NTP_transferase PF00483.23 KEY66766.1 - 1.8e-32 112.9 0.0 2.5e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KEY66766.1 - 2e-09 36.8 5.8 3.7e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KEY66766.1 - 8.2e-07 29.5 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KEY66766.1 - 3.1 7.7 5.6 4.5 7.1 0.1 3.4 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.23 KEY66767.1 - 1.1e-22 80.9 0.0 4e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEY66767.1 - 1.7e-14 53.7 0.2 2.1e-06 27.2 0.2 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KEY66767.1 - 6.5e-08 32.6 0.3 6.5e-08 32.6 0.3 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEY66767.1 - 0.0019 18.3 0.0 0.081 13.0 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEY66767.1 - 0.032 14.8 0.0 0.17 12.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 KEY66767.1 - 0.074 13.3 0.1 0.71 10.1 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF445 PF04286.12 KEY66767.1 - 0.083 12.7 0.2 11 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RICH PF05062.12 KEY66767.1 - 0.095 13.1 0.2 0.095 13.1 0.2 2.4 2 0 0 2 2 2 0 RICH domain Amidase02_C PF12123.8 KEY66767.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Peptidase_M24_C PF16188.5 KEY66767.1 - 0.18 11.9 0.2 0.53 10.4 0.2 1.7 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 MFS_1 PF07690.16 KEY66768.1 - 4.8e-36 124.4 32.3 4.8e-36 124.4 32.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66768.1 - 4.4e-15 55.5 5.1 4.4e-15 55.5 5.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY66768.1 - 2.3e-08 32.9 3.9 2.3e-08 32.9 3.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KEY66768.1 - 0.002 16.5 0.3 0.0048 15.2 0.3 1.6 1 0 0 1 1 1 1 BT1 family Podoplanin PF05808.11 KEY66769.1 - 1.9e-07 31.3 0.4 2.8e-07 30.8 0.4 1.2 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KEY66769.1 - 2.8e-05 23.4 1.8 5.1e-05 22.6 1.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mucin PF01456.17 KEY66769.1 - 0.027 14.4 12.3 0.038 14.0 12.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein LapA_dom PF06305.11 KEY66769.1 - 0.035 13.9 0.1 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VSP PF03302.13 KEY66769.1 - 0.059 12.2 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1180 PF06679.12 KEY66769.1 - 1 9.8 5.7 2.1 8.7 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_transf_25 PF01755.17 KEY66770.1 - 5.8e-20 72.0 0.0 7.5e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) NACHT_N PF17100.5 KEY66771.1 - 3.7e-32 112.0 0.0 4.7e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase DUF5082 PF16888.5 KEY66772.1 - 0.49 10.7 4.1 9.7 6.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF2244 PF10003.9 KEY66772.1 - 4.5 6.9 9.6 7.3 6.3 1.9 2.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TMEM154 PF15102.6 KEY66774.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KEY66774.1 - 0.012 16.5 0.0 0.028 15.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2232 PF09991.9 KEY66774.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PTP_tm PF18861.1 KEY66774.1 - 0.28 11.2 2.0 0.49 10.4 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TPR_MLP1_2 PF07926.12 KEY66775.1 - 8.4e-39 132.6 32.9 8.4e-39 132.6 32.9 19.2 7 5 13 20 20 20 8 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KEY66775.1 - 3.9e-07 28.1 43.5 3.9e-07 28.1 43.5 9.6 2 2 6 9 9 9 4 Protein of unknown function (DUF3584) Fez1 PF06818.15 KEY66775.1 - 0.0045 17.5 20.1 0.0045 17.5 20.1 13.2 4 3 8 13 13 13 4 Fez1 DUF1664 PF07889.12 KEY66775.1 - 0.0064 16.5 1.6 0.0064 16.5 1.6 17.0 9 4 8 18 18 18 5 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 KEY66775.1 - 0.011 15.9 0.1 0.011 15.9 0.1 23.0 20 8 5 25 25 25 0 JNK-interacting protein leucine zipper II DUF3693 PF12472.8 KEY66775.1 - 0.38 10.5 2.8 3.7 7.3 0.5 2.9 2 0 0 2 2 2 0 Phage related protein LPP PF04728.13 KEY66775.1 - 0.73 10.3 0.0 0.13 12.6 3.2 18.1 16 6 4 20 20 20 0 Lipoprotein leucine-zipper DEAD PF00270.29 KEY66776.1 - 4.4e-42 143.8 0.0 1.1e-41 142.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY66776.1 - 2.6e-27 95.4 0.0 1.6e-26 92.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY66776.1 - 0.00086 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lactamase_B_2 PF12706.7 KEY66777.1 - 6.9e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KEY66777.1 - 0.00017 21.7 0.0 0.00039 20.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KEY66777.1 - 0.00078 19.5 0.0 0.0077 16.3 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KEY66777.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CDH-cyt PF16010.5 KEY66778.1 - 1.5e-46 158.3 0.5 2.4e-46 157.7 0.5 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KEY66778.1 - 2.5e-21 76.4 0.0 5.1e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY66778.1 - 1.1e-18 68.2 0.1 2e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY66778.1 - 1e-09 38.0 0.0 0.00043 19.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 KEY66778.1 - 2.5e-08 33.7 5.0 2.5e-08 33.7 5.0 2.1 2 0 0 2 2 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.6 KEY66778.1 - 0.00013 22.1 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY66778.1 - 0.0021 17.3 0.0 0.0048 16.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY66778.1 - 0.0023 16.7 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KEY66778.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEY66778.1 - 0.026 13.8 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEY66778.1 - 0.053 12.8 0.3 0.095 11.9 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY66778.1 - 0.057 12.8 0.7 0.63 9.3 0.0 2.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY66778.1 - 0.083 13.5 0.0 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY66778.1 - 0.11 11.8 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DOMON PF03351.17 KEY66778.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 DOMON domain Glyco_hydro_11 PF00457.17 KEY66779.1 - 3.1e-79 264.7 17.0 4.5e-79 264.2 17.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PMI_typeI PF01238.21 KEY66779.1 - 8.7e-75 252.2 0.0 1.4e-74 251.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KEY66779.1 - 0.0046 16.9 0.0 0.094 12.6 0.0 2.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 KEY66779.1 - 0.01 15.5 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 KEY66779.1 - 0.098 12.4 0.3 0.4 10.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PTR2 PF00854.21 KEY66780.1 - 3.2e-49 167.8 7.6 6.6e-49 166.8 7.6 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KEY66780.1 - 2.4e-07 30.0 34.0 1.9e-05 23.8 29.4 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPgrasp_N PF18130.1 KEY66781.1 - 3e-18 66.1 0.0 6.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KEY66781.1 - 2e-10 40.5 0.0 5.8e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEY66781.1 - 0.0037 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PALP PF00291.25 KEY66782.1 - 5.9e-20 71.9 0.0 6.9e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KEY66783.1 - 1.2e-23 83.6 0.4 2e-19 69.8 0.3 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66783.1 - 1.3e-15 57.6 0.1 9.2e-12 45.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66783.1 - 1.5e-11 44.5 0.1 2.2e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 KR domain RES PF08808.11 KEY66783.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 RES domain Epimerase PF01370.21 KEY66783.1 - 0.048 13.1 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2417 PF10329.9 KEY66785.1 - 1.2e-86 289.9 2.6 1.6e-86 289.6 2.6 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) NMU PF02070.15 KEY66785.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Neuromedin U DUF2975 PF11188.8 KEY66785.1 - 6.7 6.6 10.5 4.8 7.1 4.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) RhoGAP PF00620.27 KEY66786.1 - 1.2e-34 119.3 0.0 2.5e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KEY66786.1 - 3.7e-29 100.7 36.4 6.8e-11 42.2 6.8 4.9 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 KEY66786.1 - 0.18 11.4 2.3 0.37 10.4 0.1 2.7 2 0 0 2 2 2 0 Zinc finger domain Ribosomal_L32p PF01783.23 KEY66786.1 - 6.3 7.1 6.0 2.6 8.4 0.2 3.3 3 0 0 3 3 3 0 Ribosomal L32p protein family 3Beta_HSD PF01073.19 KEY66787.1 - 5.9e-64 215.8 0.0 7.2e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY66787.1 - 1.5e-29 103.1 0.0 2.4e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY66787.1 - 9e-17 61.1 0.0 1.4e-16 60.4 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEY66787.1 - 3.2e-15 56.4 0.0 4.5e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEY66787.1 - 1.7e-10 40.5 0.1 1.2e-08 34.5 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KEY66787.1 - 3e-09 37.1 0.0 4.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEY66787.1 - 2.2e-06 27.0 0.0 3.3e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KEY66787.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HMG_box PF00505.19 KEY66789.1 - 1.3e-06 28.7 1.5 0.00064 20.1 0.3 3.9 3 2 0 3 3 3 2 HMG (high mobility group) box Med19 PF10278.9 KEY66789.1 - 0.18 11.7 11.7 0.36 10.8 11.1 1.7 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SAPS PF04499.15 KEY66789.1 - 4 6.1 5.8 6.6 5.4 5.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Proteasome PF00227.26 KEY66790.1 - 4.1e-32 111.2 0.0 4.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SIS PF01380.22 KEY66791.1 - 4.9e-54 181.7 0.8 7e-32 110.0 0.1 3.3 3 0 0 3 3 3 3 SIS domain GATase_6 PF13522.6 KEY66791.1 - 4.7e-18 65.7 0.0 9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEY66791.1 - 3.4e-10 39.9 0.0 8.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KEY66791.1 - 0.00043 19.3 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.29 KEY66792.1 - 7.1e-43 146.2 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEY66792.1 - 7.6e-13 48.2 0.1 3.2e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEY66792.1 - 5.2e-10 39.0 0.1 1.1e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEY66792.1 - 8.3e-08 32.8 0.0 6.1e-05 23.5 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEY66792.1 - 1.7e-06 28.0 0.1 3.8e-05 23.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEY66792.1 - 3.4e-06 27.3 0.0 9.2e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KEY66792.1 - 7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEY66792.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KEY66792.1 - 0.00031 20.0 0.0 0.00071 18.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KEY66792.1 - 0.00065 20.2 0.0 0.0025 18.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KEY66792.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KEY66792.1 - 0.0019 17.5 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KEY66792.1 - 0.0034 17.4 0.1 0.0089 16.0 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 KEY66792.1 - 0.0035 17.0 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KEY66792.1 - 0.0038 16.6 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEY66792.1 - 0.0041 16.9 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 KEY66792.1 - 0.0042 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEY66792.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KEY66792.1 - 0.0077 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KEY66792.1 - 0.0084 15.8 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEY66792.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KEY66792.1 - 0.012 15.4 0.9 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEY66792.1 - 0.014 15.2 0.1 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEY66792.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KEY66792.1 - 0.044 13.1 1.8 0.12 11.7 0.0 2.5 4 0 0 4 4 4 0 KaiC NACHT PF05729.12 KEY66792.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KEY66792.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KEY66792.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY66792.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain XhlA PF10779.9 KEY66792.1 - 0.097 12.9 0.4 0.36 11.0 0.4 2.0 2 0 0 2 2 1 0 Haemolysin XhlA Zeta_toxin PF06414.12 KEY66792.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KEY66792.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mago-bind PF09282.10 KEY66793.1 - 5.1e-15 55.0 3.9 1.1e-14 53.9 3.9 1.6 1 0 0 1 1 1 1 Mago binding Dsh_C PF12316.8 KEY66793.1 - 0.15 12.5 1.8 0.19 12.1 1.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4778 PF16008.5 KEY66793.1 - 0.31 11.1 4.7 0.47 10.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Nucleo_P87 PF07267.11 KEY66793.1 - 0.47 9.2 4.7 0.49 9.2 4.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ATP-synt_B PF00430.18 KEY66793.1 - 1.8 8.7 9.8 2.4 8.2 9.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Presenilin PF01080.17 KEY66793.1 - 9.1 4.9 5.8 9.9 4.8 5.8 1.1 1 0 0 1 1 1 0 Presenilin UCR_UQCRX_QCR9 PF05365.12 KEY66794.1 - 4.4e-23 81.0 1.1 5.8e-23 80.6 1.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Thioredoxin_2 PF13098.6 KEY66794.1 - 0.081 13.4 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain zf-UBR PF02207.20 KEY66795.1 - 3.6e-18 65.5 16.8 1e-17 64.1 16.8 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KEY66795.1 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CRC_subunit PF08624.10 KEY66796.1 - 3.7e-54 182.8 0.0 6.2e-54 182.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cyclin PF08613.11 KEY66797.1 - 1.7e-09 38.3 0.0 2.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEY66797.1 - 9.7e-05 22.1 0.1 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.9 KEY66798.1 - 3.3e-31 107.7 16.4 3.3e-31 107.7 16.4 2.7 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KEY66798.1 - 3.8 7.1 28.4 5.7 6.5 28.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tim54 PF11711.8 KEY66799.1 - 8.3e-135 449.4 0.2 1.1e-134 448.9 0.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 KEY66800.1 - 3.7e-57 193.7 0.0 4.3e-56 190.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66800.1 - 1.5e-25 90.0 0.2 3.2e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY66800.1 - 6.5e-05 22.0 0.2 0.00016 20.7 0.0 1.6 1 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KEY66800.1 - 0.00013 21.4 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEY66800.1 - 0.0018 17.6 0.7 0.0039 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEY66800.1 - 0.0045 17.0 4.1 0.024 14.5 0.5 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEY66800.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SF3A2 PF16835.5 KEY66801.1 - 3.2e-34 117.2 0.2 5.4e-34 116.4 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KEY66801.1 - 3.9e-06 27.1 0.9 6.8e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KEY66801.1 - 8.8e-06 25.7 0.3 1.3e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GN3L_Grn1 PF08701.11 KEY66802.1 - 4.5e-23 81.1 19.8 1e-22 80.0 19.8 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KEY66802.1 - 5.1e-16 58.8 0.0 8.5e-12 45.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY66802.1 - 1.7e-08 34.6 0.1 1.6e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KEY66802.1 - 3.3e-06 26.8 0.0 0.076 12.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEY66802.1 - 0.00046 20.3 10.6 0.18 11.9 0.2 4.2 4 1 0 4 4 4 2 Dynamin family FeoB_N PF02421.18 KEY66802.1 - 0.0043 16.6 0.4 0.072 12.6 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Nuc_deoxyri_tr2 PF15891.5 KEY66802.1 - 0.015 15.6 0.3 1 9.7 0.0 2.6 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like ORC3_N PF07034.11 KEY66802.1 - 0.023 13.8 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus CNDH2_C PF16858.5 KEY66802.1 - 0.023 14.6 16.5 0.04 13.8 16.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 KEY66802.1 - 0.036 12.3 26.0 0.06 11.6 26.0 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_18 PF13238.6 KEY66802.1 - 0.066 13.8 0.1 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KEY66802.1 - 0.56 9.2 5.9 0.13 11.2 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNB PF00773.19 KEY66803.1 - 2e-99 333.1 0.0 3e-99 332.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KEY66803.1 - 3e-31 107.2 0.2 8.7e-31 105.7 0.2 1.8 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KEY66803.1 - 6.2e-29 100.6 0.0 2.3e-28 98.8 0.0 2.0 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KEY66803.1 - 2.4e-20 72.3 0.0 8e-20 70.6 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KEY66803.1 - 2.1e-07 31.3 0.1 9.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KEY66803.1 - 8.5e-06 25.9 0.0 0.014 15.6 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Dis3l2_C_term PF17877.1 KEY66803.1 - 0.047 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal CRC_subunit PF08624.10 KEY66804.1 - 4.8e-51 172.7 0.1 6.6e-51 172.3 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 KEY66806.1 - 1.8e-09 37.7 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY66806.1 - 1.7e-06 28.4 0.1 1.7e-06 28.4 0.1 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KEY66806.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold SKG6 PF08693.10 KEY66807.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_5 PF13854.6 KEY66809.1 - 1.9e-12 46.9 12.4 9.8e-08 31.8 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 KEY66809.1 - 3.2e-06 27.1 13.6 0.16 12.0 0.1 7.4 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY66809.1 - 4.1e-05 23.7 7.5 2.5 8.5 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KEY66809.1 - 0.0024 18.1 7.0 8.1 6.9 0.1 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Adeno_E3_CR2 PF02439.15 KEY66809.1 - 0.058 13.2 1.7 0.12 12.2 1.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KEY66809.1 - 0.23 11.4 0.2 0.47 10.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Kelch_2 PF07646.15 KEY66809.1 - 0.26 11.3 11.3 21 5.3 0.0 5.6 7 1 0 7 7 7 0 Kelch motif Phage_TAC_6 PF09550.10 KEY66810.1 - 0.017 15.5 0.7 0.08 13.4 0.2 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC SYF2 PF08231.12 KEY66811.1 - 2.4e-54 184.1 17.4 2.4e-54 184.1 17.4 1.6 2 0 0 2 2 2 1 SYF2 splicing factor Epimerase PF01370.21 KEY66812.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY66812.1 - 2.6e-05 24.2 0.0 0.00011 22.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY66812.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY66812.1 - 0.012 14.8 0.1 0.081 12.1 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KEY66812.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEY66812.1 - 0.079 12.0 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain YEATS PF03366.16 KEY66813.1 - 8.8e-29 99.3 0.1 1.3e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 YEATS family DUF4279 PF14106.6 KEY66813.1 - 0.12 12.6 0.4 1.6 9.0 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Ins_P5_2-kin PF06090.12 KEY66815.1 - 1.4e-33 116.7 0.0 2e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.18 KEY66816.1 - 8.7e-37 127.1 5.6 8.7e-37 127.1 5.6 2.3 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KEY66816.1 - 2.4e-05 23.5 35.1 0.001 18.1 6.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 KEY66816.1 - 0.02 14.9 0.7 0.02 14.9 0.7 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1304) DUF2786 PF10979.8 KEY66816.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Catalase PF00199.19 KEY66817.1 - 1.6e-162 541.0 0.3 1.9e-162 540.7 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KEY66817.1 - 5.1e-43 146.3 0.1 8.1e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KEY66817.1 - 8.3e-17 61.2 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive HET PF06985.11 KEY66819.1 - 1.1e-22 80.9 0.0 4e-21 75.9 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 KEY66819.1 - 1.4e-18 66.8 0.0 2.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain EF_TS PF00889.19 KEY66819.1 - 0.06 12.9 0.1 0.52 9.9 0.0 2.3 3 0 0 3 3 3 0 Elongation factor TS AAA_22 PF13401.6 KEY66819.1 - 0.18 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyco_hydro_39 PF01229.17 KEY66820.1 - 3.5e-106 355.7 0.0 8.3e-106 354.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_cc PF11790.8 KEY66820.1 - 0.027 14.0 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Melibiase PF02065.18 KEY66821.1 - 2.1e-40 138.7 0.0 4.7e-40 137.6 0.0 1.5 1 1 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KEY66821.1 - 7.9e-08 32.2 1.4 2.1e-07 30.8 1.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Melibiase_2 PF16499.5 KEY66821.1 - 0.0001 21.6 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 KEY66821.1 - 0.00096 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Polysacc_lyase PF14099.6 KEY66822.1 - 1.5e-16 60.9 0.1 1.8e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Zn_clus PF00172.18 KEY66824.1 - 0.0036 17.4 7.7 0.0075 16.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.12 KEY66825.1 - 2.8e-29 101.2 0.0 5.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KEY66825.1 - 1.2e-17 64.0 8.3 2.9e-17 62.8 8.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KEY66825.1 - 1.7e-08 34.6 10.3 1.7e-08 34.6 10.3 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KEY66825.1 - 4.8e-08 32.6 5.5 1.7e-07 30.9 5.5 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY66825.1 - 1.6e-05 24.6 10.2 4.3e-05 23.3 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY66825.1 - 4.8e-05 23.1 10.3 0.00011 21.9 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY66825.1 - 6.8e-05 22.7 8.5 6.8e-05 22.7 8.5 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEY66825.1 - 0.00021 21.0 8.1 0.00021 21.0 8.1 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEY66825.1 - 0.00024 20.9 7.0 0.00024 20.9 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY66825.1 - 0.00032 20.6 3.7 0.00032 20.6 3.7 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEY66825.1 - 0.0017 18.6 7.9 0.0057 16.9 7.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_MLP1_2 PF07926.12 KEY66825.1 - 0.0021 18.1 9.9 0.0039 17.2 9.9 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KEY66825.1 - 0.013 15.9 2.4 0.013 15.9 2.4 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF745 PF05335.13 KEY66825.1 - 0.027 14.2 6.7 0.053 13.2 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-RING_6 PF14835.6 KEY66825.1 - 0.036 13.9 4.1 0.093 12.6 4.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein JIP_LZII PF16471.5 KEY66825.1 - 0.043 14.0 0.9 0.043 14.0 0.9 2.5 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II HDOD PF08668.12 KEY66825.1 - 0.12 11.8 0.4 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 HDOD domain zf-ANAPC11 PF12861.7 KEY66825.1 - 0.17 12.0 4.8 0.47 10.6 4.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FlgN PF05130.12 KEY66825.1 - 0.2 12.2 8.8 0.34 11.4 8.8 1.3 1 0 0 1 1 1 0 FlgN protein AKNA PF12443.8 KEY66825.1 - 0.28 11.9 3.7 0.21 12.3 1.1 2.2 1 1 0 2 2 1 0 AT-hook-containing transcription factor HALZ PF02183.18 KEY66825.1 - 0.29 11.4 3.6 0.68 10.2 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cauli_AT PF03233.13 KEY66825.1 - 0.45 10.4 1.5 0.76 9.7 1.5 1.3 1 0 0 1 1 1 0 Aphid transmission protein bZIP_1 PF00170.21 KEY66825.1 - 0.5 10.5 6.6 0.053 13.6 1.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF3450 PF11932.8 KEY66825.1 - 0.5 9.6 4.6 0.17 11.1 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 KEY66825.1 - 4.4 7.2 6.0 8.9 6.2 0.9 2.3 1 1 0 2 2 2 0 Sec34-like family bZIP_2 PF07716.15 KEY66825.1 - 5.7 7.1 10.5 0.07 13.2 0.9 2.5 3 0 0 3 3 2 0 Basic region leucine zipper Rootletin PF15035.6 KEY66825.1 - 8.9 6.3 10.8 57 3.7 10.8 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lyase_1 PF00206.20 KEY66826.1 - 5.2e-86 288.9 0.0 7.1e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KEY66826.1 - 3.5e-25 88.5 0.3 1.1e-24 86.9 0.1 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal WES_acyltransf PF03007.16 KEY66826.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Acyltransferase PF01553.21 KEY66827.1 - 5.4e-10 39.0 0.0 9.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.12 KEY66828.1 - 2.4e-72 242.9 0.0 2.8e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4577 PF15145.6 KEY66830.1 - 0.028 14.5 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2749 PF10907.8 KEY66830.1 - 0.16 12.1 3.6 0.1 12.8 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Chromo_shadow PF01393.19 KEY66831.1 - 6.6e-20 71.0 2.1 2.2e-17 62.9 0.2 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KEY66831.1 - 3.3e-13 49.3 0.7 3.3e-13 49.3 0.7 2.7 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Myc_N PF01056.18 KEY66831.1 - 0.34 10.8 3.8 0.58 10.0 3.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Chibby PF14645.6 KEY66832.1 - 0.0073 16.7 0.6 0.021 15.2 0.6 1.8 1 0 0 1 1 1 1 Chibby family zf-Di19 PF05605.12 KEY66832.1 - 0.015 15.6 1.0 0.042 14.2 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KEY66832.1 - 0.036 14.9 0.1 0.1 13.5 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KEY66832.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type HALZ PF02183.18 KEY66832.1 - 0.078 13.2 4.8 0.29 11.4 4.8 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-C2H2 PF00096.26 KEY66832.1 - 0.087 13.3 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type KCT2 PF17818.1 KEY66832.1 - 0.15 12.2 4.2 0.43 10.7 4.2 1.7 1 0 0 1 1 1 0 Keratinocyte-associated gene product bZIP_1 PF00170.21 KEY66832.1 - 0.68 10.1 9.3 0.067 13.3 3.9 2.0 2 0 0 2 2 2 0 bZIP transcription factor Laminin_II PF06009.12 KEY66832.1 - 0.8 9.7 7.4 13 5.8 0.0 4.2 4 0 0 4 4 4 0 Laminin Domain II Atg14 PF10186.9 KEY66832.1 - 1.5 7.8 8.6 0.037 13.1 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MMR1 PF08505.10 KEY66832.1 - 2.1 8.6 15.9 0.39 11.0 10.0 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CSRNP_N PF16019.5 KEY66832.1 - 4.4 7.2 11.7 0.41 10.5 5.8 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus COX15-CtaA PF02628.15 KEY66833.1 - 1.3e-111 372.8 7.1 1.6e-111 372.5 7.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.13 KEY66834.1 - 2.2e-188 628.4 64.6 2.2e-188 628.4 64.6 2.1 1 1 1 2 2 2 1 Utp14 protein Na_Ca_ex PF01699.24 KEY66835.1 - 1.3e-45 155.0 35.9 1.4e-23 83.5 16.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Dsh_C PF12316.8 KEY66836.1 - 0.059 13.8 6.0 0.11 13.0 6.0 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Glyco_hydro81C PF17652.1 KEY66837.1 - 1.5e-158 527.6 5.7 2e-158 527.2 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KEY66837.1 - 4.5e-115 384.2 0.1 6.3e-115 383.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Stn1 PF10451.9 KEY66838.1 - 2.5e-10 39.8 1.5 1.5e-08 33.9 1.5 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KEY66838.1 - 0.00012 21.9 0.2 0.00025 21.0 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KEY66838.1 - 0.079 12.8 0.0 0.55 10.1 0.0 2.2 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 DUF3340 PF11818.8 KEY66838.1 - 0.41 10.8 4.9 0.66 10.1 4.9 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DnaJ PF00226.31 KEY66839.1 - 1.1e-23 83.1 1.7 2.9e-23 81.7 1.7 1.8 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 KEY66839.1 - 0.051 13.9 1.8 2.4 8.6 0.0 3.6 3 1 0 3 3 3 0 Nif11 domain SPATIAL PF15256.6 KEY66839.1 - 2.7 8.3 13.4 3.9 7.8 10.8 2.4 2 1 0 2 2 2 0 SPATIAL Inv-AAD PF18785.1 KEY66840.1 - 1.9e-55 186.2 0.1 2.2e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KEY66840.1 - 3.5e-14 52.5 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KEY66840.1 - 0.0029 17.5 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 KEY66840.1 - 0.062 13.1 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Glyco_hydro_115 PF15979.5 KEY66841.1 - 3.9e-132 440.8 0.1 5.1e-132 440.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEY66841.1 - 6.3e-37 127.1 0.0 1.1e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KEY66841.1 - 0.00056 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus S_layer_C PF05124.12 KEY66841.1 - 0.0008 19.5 0.0 0.0025 17.8 0.0 1.8 1 1 1 2 2 2 1 S-layer like family, C-terminal region Piwi PF02171.17 KEY66842.1 - 3.1e-68 230.2 0.0 5.3e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEY66842.1 - 3.9e-12 47.0 0.0 7.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KEY66842.1 - 2.9e-09 36.4 0.2 1e-08 34.7 0.2 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KEY66842.1 - 1.7e-08 34.7 0.0 4.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KEY66842.1 - 3.5e-05 23.6 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KEY66842.1 - 0.0024 18.1 0.1 0.0059 16.8 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Abhydrolase_6 PF12697.7 KEY66843.1 - 8e-11 43.0 2.7 1.6e-10 42.0 2.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY66843.1 - 9.2e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY66843.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family MFS_1 PF07690.16 KEY66845.1 - 1.3e-39 136.1 53.6 4e-39 134.5 53.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Gryzun PF07919.12 KEY66846.1 - 6.1e-218 725.4 0.0 7.3e-218 725.1 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KEY66846.1 - 4.5e-84 282.1 5.7 1.1e-79 267.7 3.7 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KEY66846.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking MRP-L27 PF09809.9 KEY66847.1 - 3.8e-16 58.9 0.9 5.8e-16 58.3 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.13 KEY66848.1 - 8e-40 136.9 0.0 1.1e-29 103.8 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEY66848.1 - 9.5e-14 51.0 0.0 6.5e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KEY66848.1 - 0.0015 17.5 0.0 0.065 12.1 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family ISET-FN3_linker PF16625.5 KEY66848.1 - 2.7 8.6 7.0 1.7 9.2 1.6 3.0 3 0 0 3 3 3 0 Unstructured linking region I-set and fnIII on Brother of CDO WGG PF10273.9 KEY66849.1 - 3.3e-34 117.4 0.1 1.3e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 BSD PF03909.17 KEY66850.1 - 2.1e-19 69.3 2.0 3.5e-19 68.5 0.1 2.3 3 0 0 3 3 3 1 BSD domain DUF5132 PF17195.4 KEY66850.1 - 0.092 12.9 0.8 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Grg1 PF11034.8 KEY66851.1 - 5.7e-32 109.8 11.1 6.3e-32 109.6 11.1 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 PAP1 PF08601.10 KEY66852.1 - 2.7e-79 267.6 35.8 3.5e-53 181.7 0.0 3.6 2 2 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 KEY66852.1 - 4.2e-08 33.2 13.0 1.1e-07 31.9 13.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF812 PF05667.11 KEY66852.1 - 0.00034 19.6 2.1 0.00046 19.2 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SHE3 PF17078.5 KEY66852.1 - 0.0031 17.3 7.7 0.0058 16.4 7.7 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 MbeD_MobD PF04899.12 KEY66852.1 - 0.0067 16.5 2.1 0.014 15.5 2.1 1.5 1 0 0 1 1 1 1 MbeD/MobD like DUF4618 PF15397.6 KEY66852.1 - 0.011 15.1 5.6 0.018 14.4 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_Maf PF03131.17 KEY66852.1 - 0.021 15.3 10.3 0.043 14.3 10.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SlyX PF04102.12 KEY66852.1 - 0.036 14.7 2.3 0.086 13.5 2.3 1.7 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.15 KEY66852.1 - 0.071 13.2 14.1 0.25 11.5 14.1 1.9 1 1 0 1 1 1 0 Basic region leucine zipper Nop53 PF07767.11 KEY66852.1 - 0.073 12.4 14.2 0.12 11.8 14.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) COG7 PF10191.9 KEY66852.1 - 0.075 11.3 0.2 0.1 10.8 0.2 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) dsrm PF00035.26 KEY66852.1 - 0.088 13.5 0.3 0.28 11.9 0.1 1.9 2 0 0 2 2 1 0 Double-stranded RNA binding motif APG6_N PF17675.1 KEY66852.1 - 0.095 13.2 5.9 0.2 12.2 5.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 KEY66852.1 - 0.18 11.9 3.3 0.45 10.6 3.3 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation UPF0242 PF06785.11 KEY66852.1 - 0.33 11.1 4.7 0.56 10.3 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Noelin-1 PF12308.8 KEY66852.1 - 0.76 9.8 5.8 16 5.5 3.3 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein CDC45 PF02724.14 KEY66852.1 - 1.2 7.4 12.3 1.6 6.9 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KEY66853.1 - 2.7e-58 197.4 0.0 3.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY66853.1 - 2.5e-31 108.9 0.0 3.4e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY66853.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEY66853.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEY66853.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY66853.1 - 0.084 12.8 0.4 0.084 12.8 0.4 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family SGL PF08450.12 KEY66855.1 - 1e-69 234.9 0.3 1.2e-69 234.7 0.3 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KEY66855.1 - 0.0057 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Strictosidine synthase Reg_prop PF07494.11 KEY66855.1 - 0.0067 16.5 2.1 1.2 9.6 0.4 3.5 3 0 0 3 3 3 1 Two component regulator propeller DUF5074 PF16819.5 KEY66855.1 - 0.017 15.2 0.1 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5074) Arylesterase PF01731.20 KEY66855.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Arylesterase adh_short PF00106.25 KEY66856.1 - 1.5e-39 135.5 0.0 2.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY66856.1 - 4.4e-38 131.2 0.2 3.3e-32 111.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY66856.1 - 6.9e-14 52.1 0.1 1.2e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY66856.1 - 7e-06 25.7 0.0 0.00046 19.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY66856.1 - 0.036 13.4 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PAPS_reduct PF01507.19 KEY66857.1 - 6.5e-23 81.6 0.0 4e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF3632 PF12311.8 KEY66858.1 - 3.1e-39 135.2 6.9 4.1e-39 134.8 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) PXB PF12828.7 KEY66858.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 PX-associated zf-RING_2 PF13639.6 KEY66859.1 - 2.7e-08 34.0 6.3 4.2e-08 33.4 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEY66859.1 - 3.5e-07 30.4 5.7 8.9e-07 29.1 5.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEY66859.1 - 8.1e-06 25.8 3.0 3.2e-05 23.9 3.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KEY66859.1 - 0.0056 16.5 4.5 0.014 15.2 4.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY66859.1 - 0.0065 16.3 5.8 0.017 15.0 5.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KEY66859.1 - 0.03 14.4 1.2 0.03 14.4 1.2 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KEY66859.1 - 0.039 13.7 2.0 0.039 13.7 2.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KEY66859.1 - 0.05 13.4 2.4 0.084 12.7 0.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KEY66859.1 - 0.085 12.7 4.4 0.14 12.0 4.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY66859.1 - 0.28 11.3 3.1 0.28 11.2 1.7 1.8 1 1 1 2 2 2 0 RING-type zinc-finger Tmpp129 PF10272.9 KEY66859.1 - 0.54 9.5 3.2 0.8 8.9 3.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Epimerase PF01370.21 KEY66860.1 - 8.4e-11 41.8 0.0 1.6e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY66860.1 - 5.2e-10 39.5 0.2 8.7e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY66860.1 - 2.1e-05 24.2 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.10 KEY66860.1 - 2.7e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.12 KEY66860.1 - 0.11 11.7 0.0 0.45 9.6 0.0 1.9 1 1 2 3 3 3 0 Male sterility protein DUF1471 PF07338.13 KEY66860.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Flavokinase PF01687.17 KEY66861.1 - 4.2e-37 126.8 0.0 5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 KEY66862.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KEY66862.1 - 0.016 15.3 9.6 0.016 15.3 9.6 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEY66863.1 - 3.4e-36 124.9 34.8 3.4e-36 124.9 34.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66863.1 - 1.8e-07 30.4 10.1 1.8e-07 30.4 10.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY66863.1 - 1.9e-05 23.3 2.1 3.3e-05 22.5 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.18 KEY66864.1 - 2.6e-13 50.1 0.1 2.6e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) LAP1C PF05609.12 KEY66864.1 - 0.023 13.8 0.5 0.033 13.3 0.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EphA2_TM PF14575.6 KEY66864.1 - 0.037 14.9 1.5 0.088 13.7 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MASE4 PF17158.4 KEY66864.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain Transket_pyr PF02779.24 KEY66865.1 - 4.9e-43 146.9 0.0 1e-42 145.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEY66865.1 - 1e-31 109.4 0.1 2e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KEY66865.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 KEY66866.1 - 2.1e-98 329.0 0.0 2.4e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CSTF2_hinge PF14327.6 KEY66866.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3822 PF12864.7 KEY66866.1 - 0.044 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Cyt-b5 PF00173.28 KEY66867.1 - 6.2e-24 83.9 0.2 8.4e-24 83.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 KEY66867.1 - 0.0077 16.3 0.0 0.0092 16.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) TFA2_Winged_2 PF18121.1 KEY66868.1 - 1.2e-21 76.1 0.1 3.5e-21 74.7 0.1 1.9 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KEY66868.1 - 2.6e-12 46.8 0.1 8.4e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain DSBA PF01323.20 KEY66869.1 - 2.7e-23 82.8 0.0 3.1e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-C2H2 PF00096.26 KEY66870.1 - 6.3e-21 73.6 28.1 2.6e-05 24.4 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY66870.1 - 9.6e-17 60.6 30.3 1.8e-06 28.1 1.9 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY66870.1 - 4.7e-11 42.6 25.2 0.016 16.0 0.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY66870.1 - 1.4e-07 31.6 2.4 0.04 14.2 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY66870.1 - 0.0049 17.2 10.6 4.6 7.8 0.0 4.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KEY66870.1 - 0.038 13.8 8.1 2.1 8.2 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_4 PF07975.12 KEY66870.1 - 0.05 13.8 1.9 4.2 7.7 0.0 2.7 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_aberr PF17017.5 KEY66870.1 - 0.084 13.0 2.7 3.1 7.9 0.2 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KEY66870.1 - 0.21 12.2 4.6 8.8 7.0 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-MYST PF17772.1 KEY66870.1 - 0.9 9.2 2.9 3.7 7.2 0.1 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KEY66870.1 - 1.8 8.6 7.5 3.9 7.5 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KEY66870.1 - 4.3 7.6 7.9 30 4.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 KEY66870.1 - 6.3 6.9 8.2 1.9 8.6 0.7 3.1 4 0 0 4 4 4 0 XPA protein N-terminal VHS PF00790.19 KEY66871.1 - 1e-18 67.6 0.0 2.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KEY66871.1 - 6.5e-07 29.6 0.7 1.5e-06 28.4 0.7 1.7 1 0 0 1 1 1 1 GAT domain AAA_18 PF13238.6 KEY66871.1 - 0.042 14.4 0.1 0.78 10.3 0.0 2.7 2 2 0 2 2 2 0 AAA domain RAP1 PF07218.11 KEY66871.1 - 0.24 9.7 3.5 0.35 9.1 3.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PEMT PF04191.13 KEY66872.1 - 2.1e-31 108.4 4.7 3.4e-31 107.8 3.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KEY66872.1 - 0.01 15.8 0.3 0.02 14.9 0.2 1.6 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase RXT2_N PF08595.11 KEY66873.1 - 1.4e-41 142.1 0.0 5.2e-41 140.3 0.0 2.0 2 0 0 2 2 2 1 RXT2-like, N-terminal Glyco_hydro_3 PF00933.21 KEY66874.1 - 6.9e-64 216.2 0.0 9.2e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY66874.1 - 3.5e-50 170.8 0.0 6.4e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KEY66874.1 - 2e-21 75.9 1.5 5.5e-21 74.5 0.4 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KEY66874.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1442 PF07279.11 KEY66874.1 - 0.091 12.1 1.4 0.3 10.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) Glyco_hydro_31 PF01055.26 KEY66875.1 - 1.6e-107 360.5 1.6 1.9e-107 360.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KEY66875.1 - 2.5e-15 56.5 0.1 2.6e-14 53.3 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 KEY66876.1 - 9.2e-62 209.2 0.0 1.3e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KEY66876.1 - 3.5e-05 24.0 0.0 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KEY66876.1 - 0.00017 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.7 KEY66876.1 - 0.034 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 KEY66877.1 - 2.1e-18 66.8 0.0 5.8e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY66877.1 - 6.5e-13 49.0 0.2 5e-10 39.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 KEY66878.1 - 6.8e-33 114.4 0.0 1e-32 113.9 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 KEY66879.1 - 1.1e-23 84.3 0.0 1.8e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 KEY66880.1 - 3.8e-50 170.5 0.0 5.3e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEY66880.1 - 1.5e-40 139.2 0.0 2.2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Oxidored_nitro PF00148.19 KEY66880.1 - 0.087 11.5 0.0 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase RTT107_BRCT_5 PF16770.5 KEY66881.1 - 5.4e-33 112.8 0.0 2.9e-30 104.1 0.0 4.4 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KEY66881.1 - 2.6e-30 104.6 0.1 6.6e-12 45.7 0.0 6.3 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KEY66881.1 - 3.6e-30 103.7 0.2 2.4e-20 72.2 0.1 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KEY66881.1 - 5.5e-24 84.4 0.1 1.4e-07 31.8 0.1 6.1 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KEY66881.1 - 1.6e-09 37.9 0.1 0.012 15.9 0.1 3.9 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KEY66881.1 - 2e-05 24.6 0.3 0.13 12.4 0.1 3.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.12 KEY66882.1 - 5.7e-53 178.9 0.0 7.3e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2014 PF09427.10 KEY66883.1 - 8e-109 363.0 3.7 1.2e-108 362.5 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KEY66883.1 - 8.2e-17 60.9 0.9 2e-16 59.7 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4110 PF13422.6 KEY66883.1 - 0.78 9.9 3.4 2.4 8.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DND1_DSRM PF14709.7 KEY66884.1 - 0.12 12.6 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Vint PF14623.6 KEY66886.1 - 2.8e-61 206.2 0.0 4.2e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KEY66886.1 - 3.7e-27 94.3 0.0 6.6e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KEY66886.1 - 2.4e-14 54.0 0.0 7.8e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEY66886.1 - 4e-11 43.5 0.0 8.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEY66886.1 - 1.1e-10 41.7 0.0 1.2e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.20 KEY66886.1 - 0.022 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Hint module VWA_CoxE PF05762.14 KEY66886.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Thiolase_N PF00108.23 KEY66887.1 - 1.5e-68 231.0 1.6 1.9e-68 230.7 1.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY66887.1 - 2.1e-40 137.2 0.5 2.1e-40 137.2 0.5 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEY66887.1 - 0.012 15.2 2.3 0.022 14.3 0.6 2.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEY66887.1 - 6.3 6.7 6.4 7.5 6.5 0.3 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_8 PF13855.6 KEY66889.1 - 8e-30 102.4 51.4 6.2e-07 29.1 5.7 9.1 4 2 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 KEY66889.1 - 2.1e-24 85.2 48.7 1.8e-05 25.0 1.9 9.8 6 2 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEY66889.1 - 2.3e-07 30.3 35.7 0.44 10.7 1.8 10.8 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.6 KEY66889.1 - 2.9e-05 23.7 17.9 0.088 12.3 0.8 5.4 3 2 5 8 8 8 6 Leucine-rich repeat LRR_1 PF00560.33 KEY66889.1 - 0.049 14.2 42.4 15 6.6 0.2 13.1 16 1 1 17 17 17 0 Leucine Rich Repeat DUF2293 PF10056.9 KEY66890.1 - 3.9e-14 52.6 4.6 3.9e-14 52.6 4.6 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF948 PF06103.11 KEY66890.1 - 0.23 11.8 0.4 1 9.7 0.1 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) betaPIX_CC PF16523.5 KEY66890.1 - 0.33 10.8 4.8 8 6.4 0.2 2.7 2 1 1 3 3 3 0 betaPIX coiled coil Macoilin PF09726.9 KEY66892.1 - 0.32 9.5 0.1 0.47 9.0 0.1 1.1 1 0 0 1 1 1 0 Macoilin family FA_hydroxylase PF04116.13 KEY66893.1 - 1.6e-20 73.8 12.3 1.6e-20 73.8 12.3 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 KEY66893.1 - 0.054 11.5 0.0 0.063 11.3 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein DUF1230 PF06799.11 KEY66893.1 - 0.13 12.4 0.4 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF5453 PF17534.2 KEY66894.1 - 0.01 15.8 1.4 0.012 15.5 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5453) PCIF1_WW PF12237.8 KEY66894.1 - 0.11 12.1 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain YccF PF03733.13 KEY66894.1 - 7.8 7.3 9.4 0.74 10.6 2.6 2.1 1 1 1 2 2 2 0 Inner membrane component domain COX2_TM PF02790.15 KEY66895.1 - 0.3 11.2 3.2 1.3 9.3 2.6 2.5 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3671 PF12420.8 KEY66895.1 - 1 9.4 7.0 0.069 13.2 0.9 2.2 2 1 1 3 3 3 0 Protein of unknown function DUF962 PF06127.11 KEY66895.1 - 1.5 8.9 5.9 1.9 8.6 1.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF962) 4HBT PF03061.22 KEY66896.1 - 2.2e-10 40.7 0.1 5.3e-09 36.3 0.0 2.4 3 0 0 3 3 3 1 Thioesterase superfamily DUF4442 PF14539.6 KEY66896.1 - 0.00029 21.0 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Peptidase_M28 PF04389.17 KEY66897.1 - 2.4e-25 89.4 0.2 7.2e-25 87.8 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY66897.1 - 4.6e-07 29.8 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KEY66897.1 - 9.6e-07 28.1 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase fn3 PF00041.21 KEY66897.1 - 0.0017 18.7 0.3 0.0057 17.0 0.3 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Fungal_trans PF04082.18 KEY66898.1 - 1.4e-10 40.7 1.1 3e-10 39.6 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66898.1 - 3.1e-10 40.0 7.6 7.2e-10 38.8 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KEY66899.1 - 2e-40 138.9 0.1 2.5e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY66899.1 - 1.4e-10 41.6 0.2 3.9e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY66899.1 - 1.3e-06 28.2 7.7 0.17 11.4 0.1 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY66899.1 - 0.011 14.5 0.4 18 3.9 0.0 3.7 3 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KEY66899.1 - 0.037 13.1 1.5 0.22 10.6 0.0 2.8 3 1 1 4 4 4 0 FAD binding domain NAD_binding_9 PF13454.6 KEY66899.1 - 0.038 14.0 5.7 5.6 6.9 0.1 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEY66899.1 - 0.054 12.5 0.2 0.31 10.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Tricorn_PDZ PF14685.6 KEY66899.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Tfb2 PF03849.14 KEY66900.1 - 1.6e-135 451.6 0.0 2e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KEY66900.1 - 2.4e-20 72.7 1.1 4.5e-20 71.8 1.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KEY66900.1 - 0.0028 17.8 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC2_membrane PF01061.24 KEY66902.1 - 2.6e-73 245.9 55.9 7.3e-38 130.1 20.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter TANGO2 PF05742.12 KEY66902.1 - 4.1e-64 217.0 0.0 6.7e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Transport and Golgi organisation 2 ABC_tran PF00005.27 KEY66902.1 - 4e-34 118.1 0.0 1.1e-15 58.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY66902.1 - 1.6e-29 101.6 0.3 2.4e-24 85.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY66902.1 - 1.2e-11 45.0 0.1 4.4e-11 43.2 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY66902.1 - 2.4e-07 31.3 0.2 0.002 18.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KEY66902.1 - 7.2e-07 29.5 0.0 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KEY66902.1 - 9.7e-07 29.3 0.0 0.00087 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEY66902.1 - 1.2e-05 25.3 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEY66902.1 - 4e-05 24.2 0.0 0.0057 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY66902.1 - 0.00015 21.4 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY66902.1 - 0.0004 20.3 0.0 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEY66902.1 - 0.0008 19.0 0.2 0.018 14.7 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KEY66902.1 - 0.0014 18.9 0.1 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEY66902.1 - 0.0038 17.6 0.0 0.38 11.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 KEY66902.1 - 0.005 16.4 1.0 0.38 10.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KEY66902.1 - 0.0074 16.5 1.1 0.13 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KEY66902.1 - 0.011 15.7 0.5 5.2 7.0 0.1 2.8 3 0 0 3 3 3 0 NACHT domain SMC_N PF02463.19 KEY66902.1 - 0.019 14.4 0.0 0.49 9.8 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEY66902.1 - 0.033 13.9 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEY66902.1 - 0.067 13.6 0.1 4.3 7.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 KEY66902.1 - 0.13 11.3 42.1 0.13 11.4 12.6 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 KEY66902.1 - 0.18 11.9 0.1 18 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KEY66902.1 - 0.32 10.7 0.8 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KEY66902.1 - 0.32 10.7 0.9 22 4.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain Methyltransf_16 PF10294.9 KEY66903.1 - 3.6e-24 85.4 0.0 7e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KEY66903.1 - 0.00012 21.9 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66903.1 - 0.02 15.6 0.0 0.039 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KEY66903.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain dCMP_cyt_deam_1 PF00383.23 KEY66904.1 - 1.8e-07 31.0 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY66904.1 - 2e-05 24.4 0.0 4.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 MafB19-like deaminase Arginosuc_synth PF00764.19 KEY66907.1 - 1.5e-15 57.4 0.0 2e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Methyltransf_23 PF13489.6 KEY66909.1 - 9.3e-24 84.1 0.1 1.4e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY66909.1 - 3.8e-14 52.7 0.0 6.2e-13 48.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY66909.1 - 2.8e-13 50.4 0.0 6.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY66909.1 - 5.7e-13 49.3 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY66909.1 - 8.7e-11 42.4 0.0 1.3e-09 38.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY66909.1 - 6.8e-05 22.3 0.0 0.00049 19.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEY66909.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEY66909.1 - 0.0024 17.4 0.9 0.019 14.4 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase MetW PF07021.12 KEY66909.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KEY66909.1 - 0.041 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KEY66909.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KEY66909.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AAA_16 PF13191.6 KEY66912.1 - 0.026 14.9 0.0 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF1582 PF07621.11 KEY66913.1 - 6.2 6.8 7.5 4.5 7.3 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) Tcf25 PF04910.14 KEY66914.1 - 9.2e-62 209.1 0.2 1.6e-61 208.3 0.2 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 UPF0239 PF06783.11 KEY66914.1 - 0.64 10.2 5.6 2.6 8.3 5.6 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) XAP5 PF04921.14 KEY66914.1 - 1.6 8.5 8.7 3.4 7.4 8.7 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator Protocadherin PF08374.11 KEY66914.1 - 2.6 8.0 6.2 4.7 7.1 6.2 1.4 1 0 0 1 1 1 0 Protocadherin LSM14 PF12701.7 KEY66915.1 - 3.9e-29 100.6 0.0 6.6e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain V-SNARE PF05008.15 KEY66915.1 - 1.5e-21 76.5 1.2 3.6e-21 75.3 1.2 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus FDF PF09532.10 KEY66915.1 - 7.9e-21 74.9 0.0 3.7e-20 72.8 0.0 2.2 1 0 0 1 1 1 1 FDF domain V-SNARE_C PF12352.8 KEY66915.1 - 4.2e-18 65.4 2.6 4.2e-18 65.4 2.6 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus FAM219A PF15260.6 KEY66915.1 - 0.16 12.4 2.9 0.18 12.2 0.7 2.3 2 0 0 2 2 2 0 Protein family FAM219A Sec20 PF03908.13 KEY66915.1 - 0.17 11.8 0.3 0.47 10.4 0.3 1.7 1 0 0 1 1 1 0 Sec20 Amino_oxidase PF01593.24 KEY66916.1 - 1.3e-16 61.0 0.1 3.9e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY66916.1 - 2.6e-09 37.2 0.1 6.7e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY66916.1 - 0.00019 20.8 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY66916.1 - 0.0011 19.0 0.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KEY66916.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KEY66916.1 - 0.006 16.2 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEY66916.1 - 0.063 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEY66916.1 - 0.14 10.8 0.0 0.41 9.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KEY66916.1 - 0.21 10.6 0.2 0.3 10.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CtaG_Cox11 PF04442.14 KEY66917.1 - 4.8e-58 195.5 0.0 7.4e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_L26 PF16906.5 KEY66917.1 - 1.8e-36 124.4 1.7 3.5e-36 123.5 1.7 1.5 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KEY66917.1 - 6.1e-07 29.2 2.0 1.4e-06 28.1 2.0 1.5 1 0 0 1 1 1 1 KOW motif CCDC106 PF15794.5 KEY66918.1 - 0.51 10.0 4.6 1.1 9.0 4.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SET PF00856.28 KEY66919.1 - 0.022 15.2 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 SET domain DUF3328 PF11807.8 KEY66920.1 - 0.1 12.4 0.6 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) RGS12_usC PF16612.5 KEY66920.1 - 0.82 10.1 0.0 0.82 10.1 0.0 3.0 4 1 0 4 4 4 0 C-terminal unstructured region of RGS12 PARP PF00644.20 KEY66921.1 - 5.9e-11 42.3 0.1 1.4e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KEY66921.1 - 3.4e-07 30.0 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY66921.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B Pribosyl_synth PF14572.6 KEY66922.1 - 1.2e-29 103.6 0.2 1.8e-24 86.8 0.1 2.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEY66922.1 - 0.0028 17.2 0.1 0.0057 16.2 0.1 1.5 1 1 1 2 2 2 1 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.16 KEY66923.1 - 5.4e-24 84.9 0.0 6.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Polysacc_deac_2 PF04748.13 KEY66923.1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Ras PF00071.22 KEY66924.1 - 3.1e-15 56.2 0.0 1.6e-08 34.3 0.0 2.6 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KEY66924.1 - 0.0064 16.7 0.0 0.18 12.1 0.0 2.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY66924.1 - 0.0089 15.5 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_25 PF13481.6 KEY66924.1 - 0.065 12.8 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEY66924.1 - 0.098 12.4 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KEY66924.1 - 0.22 10.7 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit PseudoU_synth_1 PF01416.20 KEY66925.1 - 4.6e-33 113.9 0.0 3e-32 111.3 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase PIG-H PF10181.9 KEY66926.1 - 6.4e-28 96.4 0.6 1.1e-27 95.7 0.6 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Topoisom_I PF01028.20 KEY66927.1 - 0.18 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core DUF2284 PF10050.9 KEY66929.1 - 4.4e-05 23.3 83.0 0.19 11.5 1.0 11.6 11 2 1 13 13 13 8 Predicted metal-binding protein (DUF2284) T2SSI PF02501.17 KEY66929.1 - 0.026 14.7 8.7 52 4.1 0.0 6.9 7 1 1 8 8 8 0 Type II secretion system (T2SS), protein I TMEM247 PF15444.6 KEY66931.1 - 0.0013 18.8 0.1 0.0014 18.7 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 247 Snf7 PF03357.21 KEY66932.1 - 1.9e-20 73.2 6.5 1.9e-20 73.2 6.5 1.9 2 0 0 2 2 2 1 Snf7 GAS PF13851.6 KEY66932.1 - 0.0066 15.8 3.3 0.014 14.7 3.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding RNase_P_Rpp14 PF01900.19 KEY66932.1 - 0.034 14.4 1.0 2.3 8.5 1.0 2.8 1 1 0 1 1 1 0 Rpp14/Pop5 family Fib_alpha PF08702.10 KEY66932.1 - 1.9 8.7 7.3 0.37 11.0 3.5 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 KEY66932.1 - 1.9 6.3 4.7 0.28 9.1 1.2 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KEY66932.1 - 3.7 7.6 11.6 0.13 12.3 3.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CS PF04969.16 KEY66933.1 - 2.7e-07 31.5 0.0 4.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 CS domain Cwf_Cwc_15 PF04889.12 KEY66933.1 - 0.0038 17.0 0.6 0.005 16.6 0.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 KEY66934.1 - 1.2e-16 60.3 0.0 2.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KEY66934.1 - 0.00026 21.5 6.5 0.00026 21.5 6.5 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KEY66934.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif DFRP_C PF16543.5 KEY66935.1 - 2.2e-27 95.4 7.9 2.2e-27 95.4 7.9 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KEY66935.1 - 2.7e-06 27.2 0.8 2.7e-06 27.2 0.8 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEY66935.1 - 1.2e-05 26.0 17.7 1.9e-05 25.3 5.0 3.7 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KEY66935.1 - 0.00012 21.8 7.1 0.0041 16.9 1.8 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEY66935.1 - 0.00032 20.7 5.5 0.00032 20.7 5.5 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 KEY66935.1 - 0.02 15.1 2.6 0.52 10.5 1.1 2.6 2 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEY66935.1 - 0.021 15.3 14.3 0.14 12.7 5.5 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NT-C2 PF10358.9 KEY66935.1 - 0.13 12.0 3.7 3.2 7.5 1.6 2.3 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Metallophos PF00149.28 KEY66936.1 - 4e-09 37.3 0.2 7.9e-09 36.3 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY66936.1 - 9.4e-07 29.2 0.0 3.5e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_carr PF00153.27 KEY66938.1 - 1.3e-38 130.8 8.3 1.6e-14 53.5 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein AT_hook PF02178.19 KEY66939.1 - 0.19 11.7 23.6 0.097 12.6 2.4 3.8 3 0 0 3 3 3 0 AT hook motif DUF5535 PF17687.1 KEY66939.1 - 3.3 7.9 5.2 3.2 8.0 0.5 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5535) Meth_synt_2 PF01717.18 KEY66940.1 - 1.9e-152 507.2 0.0 1.7e-147 490.9 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEY66940.1 - 3.6e-120 401.2 0.0 5.1e-113 377.7 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KEY66940.1 - 0.0076 15.4 0.0 0.056 12.6 0.0 2.1 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 KEY66940.1 - 0.058 13.3 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Antitoxin VbhA GrpE PF01025.19 KEY66942.1 - 0.021 14.5 7.6 0.026 14.2 6.5 1.7 2 0 0 2 2 2 0 GrpE FlxA PF14282.6 KEY66942.1 - 0.056 13.4 18.6 5.1 7.1 16.4 2.8 2 1 0 2 2 2 0 FlxA-like protein Syntaxin_2 PF14523.6 KEY66942.1 - 2.1 8.7 9.3 7.4 7.0 9.3 1.8 1 1 0 1 1 1 0 Syntaxin-like protein CENP-W PF15510.6 KEY66943.1 - 2.5e-05 24.4 0.1 2.7e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 KEY66943.1 - 0.004 17.4 0.2 0.0053 17.0 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prefoldin_2 PF01920.20 KEY66944.1 - 2.5e-24 85.2 11.2 3.9e-24 84.6 11.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 KEY66944.1 - 0.054 14.1 8.6 0.44 11.1 1.8 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KEY66944.1 - 0.12 12.8 3.2 0.18 12.2 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM167 PF11652.8 KEY66944.1 - 0.64 10.5 11.0 5 7.7 0.3 3.5 1 1 3 4 4 4 0 FAM167 AAA_23 PF13476.6 KEY66944.1 - 2.1 8.8 12.0 2.8 8.4 12.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3655 PF12379.8 KEY66944.1 - 5.8 7.3 10.3 0.3 11.4 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) MFS_1 PF07690.16 KEY66945.1 - 3e-38 131.7 44.3 3e-38 131.7 44.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY66945.1 - 2.8e-17 62.7 5.2 2.8e-17 62.7 5.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 KEY66945.1 - 0.00061 18.7 1.6 0.00061 18.7 1.6 2.6 3 0 0 3 3 3 1 POT family HSP70 PF00012.20 KEY66946.1 - 2.3e-59 201.1 16.8 2.6e-54 184.5 3.6 2.6 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KEY66946.1 - 0.0042 15.9 0.1 0.039 12.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein SKA1 PF07160.12 KEY66946.1 - 0.0084 16.0 0.7 0.0084 16.0 0.7 2.8 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF2452 PF10504.9 KEY66946.1 - 0.0098 15.4 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) DUF148 PF02520.17 KEY66946.1 - 7.1 6.8 7.1 12 6.1 1.8 3.8 3 1 0 3 3 3 0 Domain of unknown function DUF148 Asp PF00026.23 KEY66947.1 - 4.8e-56 190.5 0.0 5.6e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY66947.1 - 5.1e-11 43.1 0.4 4.8e-09 36.7 0.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KEY66947.1 - 0.00022 21.0 0.0 0.00053 19.8 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KEY66947.1 - 0.0047 17.6 0.0 1.1 9.9 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease SlyX PF04102.12 KEY66948.1 - 0.023 15.3 0.0 0.041 14.5 0.0 1.4 1 0 0 1 1 1 0 SlyX PspA_IM30 PF04012.12 KEY66948.1 - 0.026 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family ADIP PF11559.8 KEY66948.1 - 0.037 14.1 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KEY66948.1 - 0.077 13.2 0.4 0.11 12.7 0.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.6 KEY66948.1 - 0.1 12.9 2.3 0.16 12.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ATG16 PF08614.11 KEY66948.1 - 0.11 12.8 0.2 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KEY66948.1 - 0.14 12.2 0.5 0.23 11.5 0.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KEY66948.1 - 0.19 11.9 0.2 0.27 11.4 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GreA_GreB_N PF03449.15 KEY66948.1 - 0.2 11.9 0.6 0.2 11.9 0.6 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal PKcGMP_CC PF16808.5 KEY66948.1 - 0.26 11.2 2.2 0.63 9.9 0.9 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fringe PF02434.16 KEY66949.1 - 0.00023 20.7 0.6 0.00086 18.8 0.4 2.0 1 1 0 1 1 1 1 Fringe-like Thioredoxin PF00085.20 KEY66950.1 - 7.6e-11 41.9 0.0 6.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 KEY66950.1 - 3.5e-08 33.6 0.0 0.009 15.9 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin-like domain HyaE PF07449.11 KEY66950.1 - 0.029 14.3 0.2 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE 2OG-FeII_Oxy_3 PF13640.6 KEY66951.1 - 1.3e-09 38.9 0.0 2.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KEY66951.1 - 0.017 15.6 0.0 0.061 13.8 0.0 2.0 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MIP PF00230.20 KEY66952.1 - 7e-46 156.8 18.1 9e-46 156.4 18.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein GDPD PF03009.17 KEY66954.1 - 6e-69 232.6 0.0 1.3e-68 231.5 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KEY66954.1 - 2.2e-27 95.4 0.2 9.9e-10 38.9 0.4 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY66954.1 - 1.5e-24 85.8 2.4 3.6e-07 30.3 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY66954.1 - 1.7e-22 79.5 5.8 3.9e-08 33.7 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY66954.1 - 1.5e-17 61.8 4.7 0.0049 17.3 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KEY66954.1 - 1.8e-15 56.6 10.5 0.013 15.9 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.19 KEY66954.1 - 2.5e-13 50.7 10.1 1.3e-05 25.4 0.0 3.8 3 1 1 4 4 4 3 SPX domain UBA_4 PF14555.6 KEY66955.1 - 0.17 11.7 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain DUF866 PF05907.13 KEY66956.1 - 2.8e-66 222.2 0.1 3.1e-66 222.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 KEY66956.1 - 0.021 14.7 0.9 0.89 9.5 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 KEY66956.1 - 0.11 12.4 0.4 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 Rubredoxin_2 PF18073.1 KEY66956.1 - 0.18 11.6 3.2 1.3 8.8 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Rpr2 PF04032.16 KEY66957.1 - 2.1e-13 50.3 1.7 2.7e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PUMA PF15826.5 KEY66957.1 - 0.079 13.1 2.6 0.11 12.7 2.2 1.4 1 1 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Ribosomal_L24e PF01246.20 KEY66957.1 - 1.5 9.1 4.9 10 6.4 0.0 2.8 2 1 0 2 2 2 0 Ribosomal protein L24e zf-ZPR1 PF03367.13 KEY66958.1 - 1.3e-113 376.2 0.0 1.8e-58 196.9 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KEY66958.1 - 0.33 11.0 4.0 3.3 7.8 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbons Antimicrobial23 PF16048.5 KEY66959.1 - 0.18 11.5 0.3 0.36 10.6 0.3 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide tRNA_int_end_N2 PF12928.7 KEY66960.1 - 7e-20 71.0 2.5 7.1e-20 71.0 1.1 1.8 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KEY66960.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.22 KEY66961.1 - 6.5e-16 59.0 0.0 8.2e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 KEY66962.1 - 3.5e-45 154.1 0.0 4e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 KEY66963.1 - 1.2e-27 96.4 0.3 2.4e-27 95.4 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.21 KEY66964.1 - 3.8e-42 144.2 0.0 1e-41 142.8 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KEY66964.1 - 0.0043 17.5 0.3 0.0043 17.5 0.3 4.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) Aldedh PF00171.22 KEY66965.1 - 1.1e-183 611.0 0.3 1.2e-183 610.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEY66965.1 - 0.12 11.8 0.0 8.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Rgp1 PF08737.10 KEY66966.1 - 6.9e-154 513.0 0.0 1.2e-153 512.3 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KEY66966.1 - 0.012 15.7 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 KEY66967.1 - 2e-11 44.3 8.7 0.0028 18.5 0.2 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Bromodomain PF00439.25 KEY66967.1 - 0.0009 19.3 0.0 0.0028 17.7 0.0 1.8 1 1 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 KEY66967.1 - 0.0042 17.4 0.0 45 4.4 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PIGA PF08288.12 KEY66968.1 - 1.9e-47 159.8 2.8 2.9e-47 159.2 0.8 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KEY66968.1 - 7.6e-28 97.6 0.3 1.1e-27 97.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEY66968.1 - 8.4e-28 97.0 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY66968.1 - 3.1e-24 85.9 0.0 6.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEY66968.1 - 1.6e-12 48.2 0.0 2.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEY66968.1 - 0.00023 21.5 0.0 0.00077 19.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEY66968.1 - 0.00029 20.9 0.1 0.00051 20.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like DEAD PF00270.29 KEY66969.1 - 1.6e-31 109.5 0.0 1.2e-15 57.7 0.0 2.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY66969.1 - 1.3e-21 77.0 0.0 3.8e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY66969.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 2.9 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KEY66969.1 - 0.31 10.5 0.0 0.31 10.5 0.0 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-C2H2 PF00096.26 KEY66970.1 - 0.016 15.7 4.9 4.3 8.0 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KEY66970.1 - 0.16 12.4 5.1 0.51 10.7 5.2 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEY66970.1 - 0.31 12.0 12.3 0.82 10.7 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Fungal_trans PF04082.18 KEY66971.1 - 3e-12 46.1 2.8 5e-12 45.4 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY66971.1 - 2.3e-07 30.8 7.9 5.1e-07 29.7 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4516 PF14990.6 KEY66971.1 - 0.14 11.9 0.7 0.32 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) CFEM PF05730.11 KEY66972.1 - 4.2e-11 42.8 12.1 7.4e-11 42.0 12.1 1.4 1 0 0 1 1 1 1 CFEM domain TetR_C_28 PF17937.1 KEY66972.1 - 0.067 13.6 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 5TM-5TMR_LYT PF07694.12 KEY66972.1 - 0.17 11.3 8.3 0.49 9.9 7.1 2.2 1 1 1 2 2 2 0 5TMR of 5TMR-LYT DUF1634 PF07843.11 KEY66972.1 - 0.73 9.9 9.9 0.3 11.2 4.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1634) DUF2470 PF10615.9 KEY66973.1 - 3.5e-22 78.8 0.9 5e-22 78.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Epimerase_2 PF02350.19 KEY66973.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DEAD PF00270.29 KEY66974.1 - 6e-19 68.5 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY66974.1 - 1.7e-18 67.0 0.0 1.9e-15 57.1 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KEY66974.1 - 1.1e-11 45.2 2.2 3e-11 43.9 2.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding SOG2 PF10428.9 KEY66975.1 - 3.2e-73 247.7 0.0 2.2e-50 172.3 0.0 4.0 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KEY66975.1 - 4e-15 55.3 7.6 9.1e-08 31.8 0.2 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KEY66975.1 - 9.2e-14 51.3 8.4 3.4e-06 27.3 1.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF2408 PF10303.9 KEY66975.1 - 0.0055 17.3 0.0 0.033 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) LRR_1 PF00560.33 KEY66975.1 - 0.006 17.0 8.4 6.3 7.8 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KEY66975.1 - 0.0092 16.0 6.1 1.7 8.9 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich repeat RPA_interact_M PF14767.6 KEY66975.1 - 0.15 12.6 0.8 6.2 7.5 0.5 2.5 2 0 0 2 2 2 0 Replication protein A interacting middle DUF2464 PF10240.9 KEY66975.1 - 0.52 9.9 1.7 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 Multivesicular body subunit 12 GCN5L1 PF06320.13 KEY66976.1 - 2.8e-14 53.2 0.4 3.9e-14 52.8 0.4 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1387 PF07139.11 KEY66976.1 - 0.015 15.1 0.3 0.021 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF812 PF05667.11 KEY66976.1 - 0.086 11.7 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Steroid_dh PF02544.16 KEY66977.1 - 1e-30 106.7 0.5 1.7e-30 106.0 0.5 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEY66977.1 - 0.00096 18.7 2.5 0.0011 18.6 1.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 KEY66977.1 - 0.012 15.4 0.1 0.033 13.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin family PEMT PF04191.13 KEY66977.1 - 0.026 14.9 2.5 0.051 14.0 0.4 2.2 2 0 0 2 2 2 0 Phospholipid methyltransferase FERM_N PF09379.10 KEY66977.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 FERM N-terminal domain DUF5346 PF17281.2 KEY66978.1 - 0.099 12.7 2.6 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5346) Ribosomal_S8e PF01201.22 KEY66979.1 - 5.4e-54 182.1 2.4 6.4e-54 181.8 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e RabGAP-TBC PF00566.18 KEY66980.1 - 6.4e-49 166.5 0.5 1.8e-47 161.8 0.5 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 KEY66980.1 - 0.00089 19.5 16.0 0.00089 19.5 16.0 3.1 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 HALZ PF02183.18 KEY66980.1 - 0.058 13.6 15.9 0.48 10.7 0.2 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KEY66980.1 - 0.061 13.2 22.9 0.22 11.4 22.9 2.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 KEY66980.1 - 0.085 13.0 19.2 0.85 9.8 4.8 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Mod_r PF07200.13 KEY66980.1 - 2.2 8.4 20.9 0.22 11.6 8.5 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KEY66980.1 - 7.8 7.2 18.0 1.8 9.2 3.0 3.4 2 1 1 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 KEY66980.1 - 9.4 6.8 31.6 0.38 11.3 9.2 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF913 PF06025.12 KEY66981.1 - 1.3e-133 445.5 0.0 1.3e-133 445.5 0.0 6.2 7 1 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KEY66981.1 - 1.4e-130 435.9 0.2 1.4e-130 435.9 0.2 4.5 4 1 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KEY66981.1 - 3.9e-93 312.3 0.0 6.4e-93 311.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KEY66981.1 - 1e-25 88.3 16.7 1.3e-08 33.9 3.7 3.9 3 0 0 3 3 3 3 Ubiquitin binding region Mut7-C PF01927.16 KEY66981.1 - 0.14 12.2 0.3 0.39 10.8 0.3 1.7 1 0 0 1 1 1 0 Mut7-C RNAse domain Ribosomal_S6e PF01092.19 KEY66982.1 - 3.4e-58 195.0 0.9 5e-58 194.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Ctf8 PF09696.10 KEY66983.1 - 1.9e-35 122.3 0.7 3.4e-34 118.2 0.7 2.4 1 1 0 1 1 1 1 Ctf8 Diphthamide_syn PF01866.17 KEY66984.1 - 9e-117 389.8 0.0 1.1e-116 389.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.20 KEY66985.1 - 2.3e-44 151.9 0.0 3.2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.25 KEY66986.1 - 4.6e-66 222.5 0.0 6.6e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEY66986.1 - 2.4e-13 50.4 1.4 3.7e-13 49.8 0.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KEY66986.1 - 0.041 14.0 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Tubulin PF00091.25 KEY66987.1 - 7e-54 183.0 0.0 1.7e-53 181.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEY66987.1 - 1.9e-49 167.0 0.1 3.9e-49 166.0 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain HMGL-like PF00682.19 KEY66987.1 - 2.9e-41 141.8 0.0 3.9e-40 138.1 0.0 2.1 1 1 0 1 1 1 1 HMGL-like Tubulin_3 PF14881.6 KEY66987.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Pga1 PF10333.9 KEY66988.1 - 0.00031 20.7 0.4 0.00077 19.4 0.0 1.8 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator WW PF00397.26 KEY66989.1 - 4.6e-09 36.2 0.0 8.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 WW domain LsmAD PF06741.13 KEY66991.1 - 7.7e-28 96.8 1.8 7.7e-28 96.8 1.8 2.4 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.20 KEY66992.1 - 8.1e-15 55.1 0.1 1.4e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEY66992.1 - 2.2e-11 44.1 0.0 4.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 KEY66993.1 - 1.6e-49 169.0 0.3 9.1e-48 163.2 0.1 2.6 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KEY66993.1 - 2.4e-15 56.4 3.5 2.5e-12 46.7 0.5 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KEY66993.1 - 5.2e-06 26.3 0.0 0.043 13.7 0.0 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit Mito_carr PF00153.27 KEY66994.1 - 4.6e-30 103.4 1.5 9.3e-15 54.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DASH_Dad3 PF08656.10 KEY66995.1 - 1.8e-18 66.4 0.0 1.8e-18 66.4 0.0 6.1 9 0 0 9 9 9 1 DASH complex subunit Dad3 Toxin_trans PF07952.12 KEY66995.1 - 0.016 14.3 0.1 0.016 14.3 0.1 2.6 3 0 0 3 3 3 0 Clostridium neurotoxin, Translocation domain TPR_19 PF14559.6 KEY66995.1 - 0.9 10.1 4.9 7.7 7.1 0.4 3.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Lip_prot_lig_C PF10437.9 KEY66995.1 - 6.1 6.9 8.0 37 4.4 0.2 5.3 4 3 2 6 6 6 0 Bacterial lipoate protein ligase C-terminus Ribosomal_S5_C PF03719.15 KEY66996.1 - 2.9e-20 71.5 0.0 4.9e-19 67.6 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KEY66996.1 - 3.9e-19 68.4 0.2 9.6e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1206 PF06724.11 KEY66997.1 - 0.049 13.7 0.8 0.078 13.1 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF5336 PF17270.2 KEY66997.1 - 0.067 12.8 0.0 0.067 12.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4083 PF13314.6 KEY66997.1 - 0.087 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) RasGEF PF00617.19 KEY66999.1 - 9.1e-45 153.0 0.2 1.4e-44 152.4 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEY66999.1 - 1.2e-11 44.8 0.2 3.1e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 KEY66999.1 - 0.0076 15.9 0.0 0.054 13.1 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 KEY66999.1 - 0.097 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KEY66999.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY66999.1 - 0.2 11.9 0.5 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain zf-HIT PF04438.16 KEY67001.1 - 9.7e-10 38.2 12.5 1.4e-09 37.7 12.5 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KEY67001.1 - 1.8e-05 24.7 6.0 2.9e-05 24.1 6.0 1.3 1 0 0 1 1 1 1 MYND finger Nfu_N PF08712.11 KEY67002.1 - 5.1e-29 100.2 0.0 1.3e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KEY67002.1 - 2.9e-27 94.6 0.1 6.2e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 KEY67003.1 - 1.8e-28 98.6 1.9 3.3e-28 97.8 1.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rrn6 PF10214.9 KEY67004.1 - 0.012 14.2 1.1 0.015 13.8 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIF_alpha PF05793.12 KEY67004.1 - 0.034 12.8 3.2 0.041 12.5 3.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L15e PF00827.17 KEY67005.1 - 4.2e-89 297.4 9.7 5.1e-89 297.1 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 KEY67005.1 - 0.17 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain PUF PF00806.19 KEY67006.1 - 4.4e-57 186.7 15.3 6.2e-08 31.9 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat adh_short PF00106.25 KEY67007.1 - 1.5e-33 115.9 1.1 4.5e-28 98.0 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67007.1 - 3.2e-21 76.0 0.8 5.2e-20 72.0 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67007.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY67007.1 - 0.0019 18.1 1.2 0.21 11.4 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Trp_DMAT PF11991.8 KEY67008.1 - 4.6e-99 332.3 0.0 6e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Cupin_7 PF12973.7 KEY67009.1 - 0.035 14.0 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 ChrR Cupin-like domain adh_short PF00106.25 KEY67010.1 - 5.2e-20 71.7 0.3 1e-16 61.0 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67010.1 - 7.9e-11 42.0 0.5 1.5e-08 34.5 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67010.1 - 1.7e-10 41.1 0.3 2.9e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY67010.1 - 0.0039 16.7 0.3 0.0076 15.7 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY67010.1 - 0.013 14.7 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.22 KEY67011.1 - 3e-77 260.3 0.0 3.8e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KEY67012.1 - 2.9e-50 171.0 5.9 3.7e-25 88.8 4.2 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY67012.1 - 3.1e-38 131.2 3.5 1.1e-30 106.5 1.9 3.0 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY67012.1 - 7.1e-05 22.8 0.2 0.00011 22.2 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KEY67013.1 - 6.3e-41 140.0 0.0 8.5e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67013.1 - 2.6e-30 105.7 0.0 3.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67013.1 - 1.3e-05 25.2 0.1 2.9e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY67013.1 - 0.00018 21.0 0.1 0.0003 20.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KEY67013.1 - 0.004 17.1 0.2 0.029 14.3 0.0 2.0 1 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KEY67013.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 KEY67013.1 - 0.038 14.2 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 KEY67013.1 - 0.038 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 KEY67013.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ketoacyl-synt PF00109.26 KEY67014.1 - 2.6e-67 227.1 0.0 4.8e-67 226.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEY67014.1 - 1.1e-56 192.2 0.0 1.9e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY67014.1 - 4e-53 181.0 0.0 7e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY67014.1 - 2.6e-45 154.5 0.1 8.8e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEY67014.1 - 3.2e-38 130.4 0.2 1.2e-37 128.5 0.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY67014.1 - 9.4e-17 61.5 0.0 5.4e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KEY67014.1 - 2e-14 53.7 0.0 6.9e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY67014.1 - 1.8e-12 48.5 0.0 1.7e-11 45.3 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY67014.1 - 4.2e-12 45.9 1.8 1.2e-10 41.1 0.0 3.4 4 0 0 4 4 4 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67014.1 - 1.6e-06 27.9 0.0 5e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KEY67014.1 - 3.3e-06 26.9 0.1 8.1e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY67014.1 - 0.013 15.8 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site p450 PF00067.22 KEY67015.1 - 3.4e-66 223.9 0.0 4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY67016.1 - 1.1e-21 77.0 0.8 2.3e-21 76.0 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY67016.1 - 0.0083 16.2 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Filament PF00038.21 KEY67017.1 - 0.071 12.7 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein PKcGMP_CC PF16808.5 KEY67017.1 - 0.14 12.0 0.4 0.49 10.3 0.4 2.0 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Glyco_hydro_61 PF03443.14 KEY67018.1 - 5.4e-23 82.0 0.0 7.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 KEY67019.1 - 1.7e-11 43.5 1.4 1.6e-10 40.3 1.4 2.2 1 1 0 1 1 1 1 Cytochrome P450 IBR PF01485.21 KEY67021.1 - 1.4e-12 47.6 38.0 1.7e-08 34.6 6.6 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KEY67021.1 - 0.00076 19.5 2.0 0.00076 19.5 2.0 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEY67021.1 - 0.0037 17.1 4.3 0.0037 17.1 4.3 3.8 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY67021.1 - 0.0073 16.1 2.7 0.0073 16.1 2.7 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67021.1 - 0.02 15.2 6.6 0.02 15.2 6.6 3.7 3 1 1 4 4 4 0 Ring finger domain zf-RING_UBOX PF13445.6 KEY67022.1 - 0.00044 20.2 2.3 0.0015 18.5 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY67022.1 - 0.0042 16.9 3.7 0.0042 16.9 3.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY67022.1 - 0.0063 16.4 7.7 0.0063 16.4 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67022.1 - 0.0079 16.5 7.6 0.0079 16.5 7.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KEY67022.1 - 0.011 15.6 7.2 0.011 15.6 7.2 2.3 2 1 0 2 2 2 0 zinc-RING finger domain IBR PF01485.21 KEY67022.1 - 0.056 13.7 18.7 0.75 10.1 10.1 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Aldedh PF00171.22 KEY67023.1 - 1.1e-124 416.5 0.0 1.4e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEY67023.1 - 0.00076 18.6 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) OmdA PF13376.6 KEY67023.1 - 0.18 11.9 0.3 0.32 11.0 0.3 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF2961 PF11175.8 KEY67024.1 - 1e-85 287.1 4.4 1.3e-85 286.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Fungal_trans PF04082.18 KEY67025.1 - 8e-09 34.9 0.4 1.1e-08 34.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 KEY67026.1 - 2.1e-53 181.9 0.0 3.5e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY67026.1 - 6.5e-24 84.7 0.0 9.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KEY67026.1 - 0.0048 16.2 0.1 0.025 13.9 0.1 1.8 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KEY67026.1 - 0.097 12.7 3.9 0.89 9.8 0.1 3.3 3 0 0 3 3 3 0 BNR/Asp-box repeat Sugar_tr PF00083.24 KEY67027.1 - 2.5e-64 217.8 22.3 3.3e-64 217.4 22.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY67027.1 - 2.7e-12 46.3 28.3 2.7e-12 46.3 28.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 KEY67028.1 - 3.2e-10 40.5 0.2 8.9e-10 39.1 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ProSAAS PF07259.12 KEY67028.1 - 0.096 12.6 0.2 11 5.9 0.1 2.5 2 0 0 2 2 2 0 ProSAAS precursor Abhydrolase_6 PF12697.7 KEY67029.1 - 7.5e-13 49.6 0.0 8.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY67029.1 - 5.8e-05 22.5 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 KEY67029.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S28 PF05577.12 KEY67030.1 - 7.6e-47 160.1 0.1 1.9e-45 155.5 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FAD_binding_3 PF01494.19 KEY67031.1 - 6.9e-28 97.9 0.0 2.6e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY67031.1 - 7.8e-08 32.4 0.1 2.2e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY67031.1 - 1e-06 28.3 0.1 5.7e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY67031.1 - 3.2e-06 27.0 0.3 6e-06 26.1 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY67031.1 - 3.6e-06 27.5 0.1 1.9e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY67031.1 - 4.5e-06 26.0 0.6 0.049 12.7 0.2 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY67031.1 - 9.2e-06 25.1 0.0 0.00013 21.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY67031.1 - 3.5e-05 23.3 0.2 0.014 14.7 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KEY67031.1 - 0.00044 19.2 0.1 0.0018 17.2 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KEY67031.1 - 0.00048 19.4 0.3 0.001 18.3 0.2 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEY67031.1 - 0.001 17.9 0.1 0.0021 16.8 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEY67031.1 - 0.0013 18.2 0.1 0.0019 17.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY67031.1 - 0.0016 17.6 1.1 0.0019 17.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KEY67031.1 - 0.0048 16.0 0.0 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 KEY67031.1 - 0.0056 16.3 0.0 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KEY67031.1 - 0.016 14.5 0.1 0.056 12.7 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KEY67031.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KEY67031.1 - 0.042 14.1 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 KEY67031.1 - 0.098 11.7 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DOPA_dioxygen PF08883.11 KEY67032.1 - 1.1e-40 138.1 0.0 1.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Fasciclin PF02469.22 KEY67033.1 - 3.1e-46 156.7 0.5 5.1e-26 91.4 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain adh_short PF00106.25 KEY67034.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF2796 PF10986.8 KEY67035.1 - 0.016 15.2 0.5 0.035 14.1 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) DUF515 PF04415.12 KEY67035.1 - 0.62 8.4 2.5 0.86 7.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) UPRTase PF14681.6 KEY67036.1 - 1.4e-65 220.7 0.0 1.7e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEY67036.1 - 0.00021 20.8 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.22 KEY67037.1 - 6.5e-132 440.3 0.0 7.4e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPRTase PF14681.6 KEY67038.1 - 4.5e-48 163.4 0.0 6.9e-45 153.0 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEY67038.1 - 2.6e-09 36.8 0.1 4.3e-09 36.1 0.1 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF1688 PF07958.11 KEY67039.1 - 7.4e-159 529.0 0.0 8.3e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 KEY67039.1 - 0.0016 18.1 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family GTP_CH_N PF12471.8 KEY67040.1 - 2.2e-86 288.5 0.0 3e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KEY67040.1 - 4e-17 62.3 0.0 5.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Bradykinin PF06753.12 KEY67042.1 - 0.016 14.9 0.5 0.035 13.8 0.5 1.5 1 0 0 1 1 1 0 Bradykinin ABC2_membrane PF01061.24 KEY67043.1 - 7e-90 300.0 35.5 6.2e-49 166.3 12.9 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY67043.1 - 2e-39 135.3 0.0 2.7e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY67043.1 - 1.3e-29 101.9 0.1 8.7e-25 86.5 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEY67043.1 - 2.8e-12 46.4 27.8 7e-08 32.0 14.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KEY67043.1 - 3.5e-07 30.8 0.1 0.00024 21.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KEY67043.1 - 5.4e-06 26.1 0.1 0.00069 19.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY67043.1 - 0.0001 22.3 0.0 0.0042 17.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KEY67043.1 - 0.00019 21.6 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEY67043.1 - 0.00027 21.2 0.6 0.23 11.7 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEY67043.1 - 0.00035 20.2 0.1 0.057 13.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KEY67043.1 - 0.00063 20.3 0.0 0.74 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEY67043.1 - 0.00093 19.5 0.0 0.33 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEY67043.1 - 0.013 15.1 0.9 4.3 6.9 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.6 KEY67043.1 - 0.015 15.9 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_30 PF13604.6 KEY67043.1 - 0.027 14.2 0.1 4.2 7.1 0.5 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEY67043.1 - 0.044 13.7 0.7 2.6 7.9 0.3 2.3 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 KEY67043.1 - 0.062 13.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KEY67043.1 - 0.12 12.4 0.4 18 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FA_desaturase PF00487.24 KEY67044.1 - 2.7e-27 96.2 13.5 5.1e-27 95.3 13.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KEY67044.1 - 3.6e-09 36.9 0.0 1.8e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) RabGAP-TBC PF00566.18 KEY67045.1 - 4.7e-33 114.6 0.0 7.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KEY67045.1 - 2.4e-07 29.4 1.3 3.7e-07 28.8 1.3 1.2 1 0 0 1 1 1 1 SBE2, cell-wall formation HET PF06985.11 KEY67046.1 - 8.9e-35 120.2 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cpn60_TCP1 PF00118.24 KEY67048.1 - 2.7e-141 471.5 12.7 3.2e-141 471.3 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KEY67048.1 - 0.078 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KEY67048.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat eIF2A PF08662.11 KEY67049.1 - 4e-40 137.8 1.9 3e-37 128.4 0.2 4.4 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KEY67049.1 - 0.00019 21.7 0.1 28 5.1 0.0 5.8 6 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KEY67049.1 - 0.00044 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KEY67049.1 - 0.058 14.3 1.1 6.7 7.8 0.0 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat NIPSNAP PF07978.13 KEY67049.1 - 0.17 12.2 1.3 12 6.1 0.0 3.5 3 0 0 3 3 3 0 NIPSNAP PRP3 PF08572.10 KEY67049.1 - 1.2 8.8 4.1 2.8 7.6 4.1 1.6 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Ribonuc_2-5A PF06479.12 KEY67050.1 - 1.5e-43 148.0 0.0 2.9e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KEY67050.1 - 1.5e-33 116.3 0.0 7.2e-32 110.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67050.1 - 9e-15 54.7 0.0 6.8e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KEY67050.1 - 1.1e-06 28.2 0.2 2.1e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 KEY67050.1 - 0.00019 21.1 0.2 0.022 14.4 0.0 2.7 2 1 1 3 3 3 2 PQQ-like domain Kdo PF06293.14 KEY67050.1 - 0.00053 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY67050.1 - 0.0041 17.1 2.1 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY67050.1 - 0.0056 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PQQ_3 PF13570.6 KEY67050.1 - 0.08 13.5 0.4 49 4.6 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain zf-C3HC4_3 PF13920.6 KEY67051.1 - 4.4e-06 26.4 6.8 4.4e-06 26.4 6.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KEY67052.1 - 1.4e-29 101.8 0.7 3.9e-29 100.3 0.2 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 KEY67052.1 - 2.6e-15 56.1 1.0 2.6e-15 56.1 1.0 2.4 3 0 0 3 3 3 1 DEK C terminal domain SRP54_N PF02881.19 KEY67052.1 - 0.1 12.9 1.3 2.5 8.4 0.3 2.6 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain SOBP PF15279.6 KEY67052.1 - 0.13 12.8 4.4 0.16 12.6 4.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 KEY67052.1 - 3.7 5.5 4.9 4.3 5.4 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KEY67052.1 - 5.3 5.7 4.3 6.1 5.5 4.3 1.1 1 0 0 1 1 1 0 Presenilin GH131_N PF18271.1 KEY67053.1 - 2.3e-63 214.3 0.0 2.7e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Exo_endo_phos PF03372.23 KEY67054.1 - 2.9e-05 23.7 1.2 4.6e-05 23.1 1.2 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mur_ligase_C PF02875.21 KEY67054.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Glucosaminidase PF01832.20 KEY67058.1 - 0.022 15.2 0.0 0.042 14.4 0.0 1.5 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT_2 PF13406.6 KEY67058.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain F-box-like PF12937.7 KEY67059.1 - 0.0025 17.7 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3712 PF12505.8 KEY67061.1 - 4.2e-22 78.7 0.2 1.1e-21 77.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) CRR7 PF12095.8 KEY67062.1 - 0.00064 20.1 8.2 11 6.6 0.0 5.9 3 1 2 5 5 5 1 Protein CHLORORESPIRATORY REDUCTION 7 LIN52 PF10044.9 KEY67062.1 - 0.0011 19.6 0.0 6.3 7.6 0.0 5.0 5 2 0 5 5 5 1 Retinal tissue protein Adaptin_N PF01602.20 KEY67062.1 - 0.0013 17.4 1.4 11 4.4 0.4 5.3 3 2 2 6 6 6 1 Adaptin N terminal region EH_Signature PF15611.6 KEY67062.1 - 0.036 13.5 0.1 3.5 7.0 0.0 2.4 1 1 1 2 2 2 0 EH_Signature domain NAF PF03822.14 KEY67062.1 - 0.11 12.7 1.1 1.5e+02 2.6 0.0 5.0 4 0 0 4 4 4 0 NAF domain Glu-tRNAGln PF02686.15 KEY67062.1 - 1.3 9.3 3.3 3.4e+02 1.6 0.0 5.8 7 1 1 8 8 8 0 Glu-tRNAGln amidotransferase C subunit Dsl1_N PF11988.8 KEY67062.1 - 2.8 6.8 7.3 2.2 7.2 0.2 3.5 4 0 0 4 4 4 0 Retrograde transport protein Dsl1 N terminal HET PF06985.11 KEY67063.1 - 2.7e-30 105.6 0.0 4.4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Plant_tran PF04827.14 KEY67064.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein NUDIX PF00293.28 KEY67066.1 - 2.2e-20 73.1 0.4 2.8e-20 72.7 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEY67066.1 - 2.7e-06 27.3 0.1 5.2e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain McyA_C PF12593.8 KEY67066.1 - 0.15 11.9 0.3 0.37 10.6 0.3 1.7 1 0 0 1 1 1 0 Microcystin synthetase C terminal DUF3445 PF11927.8 KEY67067.1 - 1.8e-74 250.2 0.0 2.2e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) TnsD PF15978.5 KEY67067.1 - 0.068 12.1 0.0 0.2 10.6 0.0 1.5 1 1 1 2 2 2 0 Tn7-like transposition protein D p450 PF00067.22 KEY67068.1 - 1.2e-34 119.9 0.0 1.9e-31 109.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_C97 PF05903.14 KEY67069.1 - 0.00022 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 KEY67069.1 - 0.0038 16.9 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) LRAT PF04970.13 KEY67069.1 - 0.015 15.6 0.3 0.34 11.2 0.0 2.2 1 1 0 2 2 2 0 Lecithin retinol acyltransferase DUF778 PF05608.12 KEY67069.1 - 0.023 15.1 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF4796 PF16044.5 KEY67069.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) AIM24 PF01987.17 KEY67070.1 - 5.7e-47 160.1 0.0 6.6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Methyltransf_32 PF13679.6 KEY67071.1 - 8.4e-23 81.1 0.1 1.5e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY67071.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY67071.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KEY67071.1 - 0.0011 19.6 0.0 0.0041 17.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY67071.1 - 0.0014 18.5 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY67071.1 - 0.027 15.2 0.0 0.085 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KEY67071.1 - 0.032 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 KEY67071.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PNP_UDP_1 PF01048.20 KEY67072.1 - 2.9e-05 23.4 0.0 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 2 Phosphorylase superfamily NUDIX PF00293.28 KEY67073.1 - 7.9e-20 71.2 0.2 9.5e-20 71.0 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEY67073.1 - 0.00089 19.2 0.1 0.0013 18.7 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain AltA1 PF16541.5 KEY67074.1 - 5.9e-16 59.3 0.0 7.4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Pec_lyase_C PF00544.19 KEY67075.1 - 2.8e-48 164.3 4.9 3.6e-48 163.9 4.9 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY67075.1 - 2.8e-06 27.3 11.5 0.00016 21.6 11.2 2.3 1 1 0 1 1 1 1 Right handed beta helix region LPMO_10 PF03067.15 KEY67076.1 - 4.3e-07 30.8 0.0 5.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-AN1 PF01428.16 KEY67077.1 - 2.2e-12 46.9 4.3 2.2e-12 46.9 4.3 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Hydantoinase_B PF02538.14 KEY67078.1 - 6.8e-220 730.8 0.1 9.2e-220 730.4 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEY67078.1 - 6.4e-104 347.3 0.5 6.4e-104 347.3 0.5 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEY67078.1 - 6.3e-64 214.9 1.6 2.5e-62 209.7 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region NmrA PF05368.13 KEY67079.1 - 3.2e-07 30.2 0.0 4.2e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KEY67079.1 - 5.2e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding A_deaminase PF00962.22 KEY67080.1 - 6.8e-25 88.1 0.0 1.5e-24 86.9 0.0 1.6 2 1 0 2 2 2 1 Adenosine/AMP deaminase Acyl-CoA_dh_1 PF00441.24 KEY67081.1 - 1.2e-14 54.7 0.2 7.4e-14 52.2 0.2 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEY67081.1 - 2.3e-11 43.8 0.0 5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 KEY67081.1 - 2.8e-07 30.6 0.0 2.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEY67081.1 - 0.00011 22.4 0.0 0.11 12.8 0.0 2.8 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain APG5 PF04106.12 KEY67083.1 - 2.7e-47 161.3 0.1 1e-46 159.4 0.1 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 WD40 PF00400.32 KEY67084.1 - 2.3e-22 78.8 15.7 2.2e-05 25.1 0.6 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY67084.1 - 2.6e-13 50.1 1.6 0.0022 18.2 0.1 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY67084.1 - 0.00087 19.2 0.0 0.084 12.7 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KEY67084.1 - 0.0021 17.7 0.1 0.1 12.2 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KEY67084.1 - 0.0033 16.1 0.9 4.1 5.9 0.2 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KEY67084.1 - 0.01 16.3 7.3 3.3 8.3 0.0 4.6 4 1 0 4 4 4 1 PQQ-like domain UAF_Rrn10 PF05234.11 KEY67085.1 - 0.0075 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Zn_clus PF00172.18 KEY67087.1 - 3.1e-08 33.6 13.7 4.9e-08 33.0 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCSMST1 PF15013.6 KEY67089.1 - 0.045 13.9 0.2 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 CCSMST1 family FAD_binding_4 PF01565.23 KEY67090.1 - 1.4e-21 76.7 3.2 2.4e-21 75.9 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY67090.1 - 2.2e-10 40.5 0.0 3.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Phage_Arf PF17585.2 KEY67090.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Accessory recombination function protein Abhydrolase_6 PF12697.7 KEY67091.1 - 5.3e-21 76.2 2.7 7.2e-21 75.8 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY67091.1 - 2.8e-20 73.1 1.4 3.9e-20 72.6 0.5 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY67091.1 - 4.9e-14 52.2 0.3 7.4e-14 51.6 0.3 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEY67091.1 - 1.1e-06 28.9 0.1 2.3e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase PF07224.11 KEY67091.1 - 3.1e-06 26.5 0.0 5.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF1057 PF06342.12 KEY67091.1 - 6.1e-05 22.2 0.0 8.6e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 KEY67091.1 - 0.0005 19.7 0.1 0.004 16.7 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KEY67091.1 - 0.0052 15.7 0.0 0.0095 14.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KEY67091.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 KEY67091.1 - 0.021 13.5 0.0 0.59 8.8 0.0 2.0 2 0 0 2 2 2 0 Ndr family Peptidase_S9 PF00326.21 KEY67091.1 - 0.023 14.2 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Palm_thioest PF02089.15 KEY67091.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ferric_reduct PF01794.19 KEY67092.1 - 4.6e-22 78.4 19.6 1.6e-21 76.7 19.6 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY67092.1 - 9.6e-05 22.6 0.1 0.092 12.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY67092.1 - 0.02 15.0 0.3 0.15 12.1 0.3 2.3 1 1 0 1 1 1 0 FAD-binding domain NAD_binding_1 PF00175.21 KEY67092.1 - 0.091 13.4 0.0 0.33 11.6 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CFEM PF05730.11 KEY67093.1 - 0.003 17.6 4.0 0.003 17.6 4.0 2.0 2 1 0 2 2 2 1 CFEM domain MFS_1 PF07690.16 KEY67094.1 - 1.1e-27 96.9 57.5 3.3e-25 88.8 45.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEY67095.1 - 6.3e-39 133.9 32.7 6.3e-39 133.9 32.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY67095.1 - 6.3e-07 28.2 3.3 1.1e-06 27.3 3.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KEY67095.1 - 7.7e-05 21.1 1.2 0.00014 20.2 1.2 1.4 1 0 0 1 1 1 1 BT1 family Folate_carrier PF01770.18 KEY67095.1 - 0.0014 17.4 1.5 0.0016 17.2 0.7 1.4 1 1 0 1 1 1 1 Reduced folate carrier Ferritin_2 PF13668.6 KEY67096.1 - 1.7e-12 47.7 0.1 2.7e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain ABC2_membrane PF01061.24 KEY67097.1 - 1.4e-68 230.4 53.6 1.9e-37 128.7 24.9 2.8 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY67097.1 - 9.6e-35 120.1 0.0 6.2e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY67097.1 - 5.4e-22 77.5 0.9 1.1e-19 70.1 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEY67097.1 - 2.8e-13 49.7 31.5 9.7e-10 38.1 6.9 3.1 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KEY67097.1 - 1.3e-06 28.9 0.7 0.00032 21.1 0.1 3.0 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY67097.1 - 2.6e-05 24.2 1.0 0.0002 21.3 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KEY67097.1 - 6e-05 22.6 0.3 0.0047 16.4 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY67097.1 - 0.0001 22.0 1.3 0.032 14.0 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY67097.1 - 0.00068 19.5 0.2 1.2 8.9 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEY67097.1 - 0.0014 18.9 0.6 0.28 11.5 0.3 3.3 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KEY67097.1 - 0.0035 17.9 0.0 0.0087 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY67097.1 - 0.0082 15.9 0.7 0.14 11.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KEY67097.1 - 0.0092 15.6 0.2 0.064 12.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KEY67097.1 - 0.016 15.1 0.5 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 KEY67097.1 - 0.02 15.0 0.6 0.19 11.8 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEY67097.1 - 0.029 13.7 1.8 0.76 9.1 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KEY67097.1 - 0.067 13.4 0.8 1.1 9.4 0.6 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEY67097.1 - 0.55 10.3 1.3 1.8 8.6 1.3 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 KEY67097.1 - 1.8 8.5 3.5 11 5.9 0.8 2.5 2 0 0 2 2 2 0 NACHT domain NTP_transf_9 PF04248.12 KEY67098.1 - 1.3e-39 133.9 0.1 1.7e-30 104.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) NACHT PF05729.12 KEY67099.1 - 1.1e-09 38.5 0.2 8.7e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEY67099.1 - 8.3e-05 23.0 0.0 0.00067 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KEY67099.1 - 0.0016 18.8 0.1 0.005 17.2 0.1 1.9 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KEY67099.1 - 0.0042 17.4 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY67099.1 - 0.019 14.8 0.7 0.042 13.7 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase AAA_18 PF13238.6 KEY67099.1 - 0.02 15.4 0.0 0.059 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEY67099.1 - 0.026 14.2 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEY67099.1 - 0.056 13.6 0.8 0.16 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KEY67099.1 - 0.057 13.9 0.2 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KEY67099.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEY67099.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 KEY67099.1 - 0.13 11.4 6.9 0.48 9.6 2.2 2.8 2 1 0 2 2 2 0 KAP family P-loop domain SF-assemblin PF06705.11 KEY67099.1 - 0.39 10.0 4.6 0.73 9.1 4.6 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin PhyH PF05721.13 KEY67100.1 - 9e-23 81.6 0.1 1.7e-22 80.7 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CMAS PF02353.20 KEY67101.1 - 5.5e-72 242.3 0.0 9.7e-72 241.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEY67101.1 - 2.7e-18 66.4 0.0 6.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY67101.1 - 7.7e-16 58.5 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY67101.1 - 4.5e-12 46.1 0.0 7.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY67101.1 - 2.2e-09 37.3 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY67101.1 - 2.7e-09 37.6 0.0 6.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY67101.1 - 1.1e-06 28.1 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEY67101.1 - 8.9e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KEY67101.1 - 0.00024 21.1 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY67101.1 - 0.00043 20.1 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEY67101.1 - 0.00054 19.1 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 KEY67101.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 KEY67101.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 KEY67101.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KEY67101.1 - 0.08 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 KEY67101.1 - 0.086 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UTP15_C PF09384.10 KEY67102.1 - 2.6e-50 169.9 0.0 3.9e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KEY67102.1 - 5e-20 71.5 4.7 6.1e-05 23.7 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY67102.1 - 1.7e-08 34.7 0.1 0.044 14.1 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KEY67102.1 - 0.0038 16.6 0.2 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 KEY67102.1 - 0.025 13.2 0.1 4.3 5.9 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 C2 PF00168.30 KEY67103.1 - 5.4e-15 55.6 0.0 8.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain GAF_2 PF13185.6 KEY67104.1 - 6.7e-09 36.2 0.0 8.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KEY67104.1 - 0.002 18.8 0.0 0.0025 18.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KEY67104.1 - 0.053 13.9 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 GAF domain AlaDh_PNT_C PF01262.21 KEY67104.1 - 0.088 12.1 0.1 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain LETM1 PF07766.13 KEY67105.1 - 8.9e-10 38.3 0.1 4.6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein SCP2 PF02036.17 KEY67106.1 - 6.3e-22 78.0 0.3 7.3e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KEY67106.1 - 2.7e-05 24.4 0.2 3.9e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KEY67106.1 - 0.016 15.6 0.1 0.02 15.3 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain NMO PF03060.15 KEY67107.1 - 4.2e-32 111.8 1.3 3.2e-25 89.2 0.5 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KEY67107.1 - 2.1e-09 36.9 3.1 7.5e-09 35.0 3.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY67107.1 - 1e-08 34.6 2.1 1.6e-08 34.0 2.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEY67107.1 - 9.6e-05 21.7 1.0 0.00016 20.9 1.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase OpuAC PF04069.12 KEY67107.1 - 0.031 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Aldo_ket_red PF00248.21 KEY67108.1 - 3.3e-68 230.1 0.0 3.8e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 KEY67108.1 - 0.06 13.6 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 FliG middle domain Pkinase PF00069.25 KEY67109.1 - 8.1e-27 94.2 0.0 1.3e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67109.1 - 9.6e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY67109.1 - 3.9e-07 29.2 0.0 7.2e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M44 PF03410.13 KEY67109.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox EMP24_GP25L PF01105.24 KEY67110.1 - 5.2e-49 166.7 0.0 5.9e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 KEY67111.1 - 1.2e-30 105.5 0.3 2.5e-30 104.5 0.3 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Mito_fiss_reg PF05308.11 KEY67112.1 - 0.32 11.0 1.5 0.5 10.4 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Pec_lyase_C PF00544.19 KEY67113.1 - 1e-13 51.4 4.3 3e-12 46.6 4.2 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY67113.1 - 1.8e-06 27.9 8.5 1.3e-05 25.2 7.7 2.2 1 1 1 2 2 2 2 Right handed beta helix region Arrestin_C PF02752.22 KEY67115.1 - 0.00015 22.2 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KEY67115.1 - 0.026 14.6 0.0 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF2790 PF10976.8 KEY67115.1 - 0.033 14.2 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) CheX PF13690.6 KEY67115.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Fungal_trans PF04082.18 KEY67116.1 - 4.2e-11 42.4 1.9 5.8e-11 41.9 1.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67116.1 - 5.4e-07 29.6 10.0 5.4e-07 29.6 10.0 3.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.7 KEY67117.1 - 1.7e-08 34.5 0.0 3.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY67117.1 - 6.5e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY67117.1 - 9.3e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KEY67117.1 - 0.083 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 KEY67119.1 - 1e-45 156.3 56.6 1.3e-45 156.0 56.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY67119.1 - 3.6e-23 81.9 49.9 9.9e-23 80.5 49.9 1.7 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KEY67120.1 - 4e-30 104.9 16.3 4e-30 104.9 16.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TNFR_16_TM PF18422.1 KEY67120.1 - 0.11 12.5 3.3 4.6 7.3 0.3 2.9 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF5316 PF17247.2 KEY67120.1 - 0.29 11.2 3.0 3.9 7.5 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5316) FMO-like PF00743.19 KEY67121.1 - 1.3e-28 99.8 0.0 2e-16 59.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY67121.1 - 2.4e-11 43.5 0.7 1.8e-09 37.3 0.1 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY67121.1 - 4e-11 42.7 0.0 3.8e-10 39.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY67121.1 - 1.1e-09 38.0 0.1 1.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY67121.1 - 6.1e-06 26.3 0.1 0.0001 22.3 0.1 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY67121.1 - 3.2e-05 24.1 0.0 9.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY67121.1 - 0.0037 16.9 0.2 0.89 9.1 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY67121.1 - 0.006 17.1 3.0 0.39 11.3 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY67121.1 - 0.014 14.6 0.4 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KEY67121.1 - 0.019 15.0 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KEY67121.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GMC_oxred_N PF00732.19 KEY67122.1 - 7.8e-57 192.9 0.0 1e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY67122.1 - 3.3e-30 105.5 0.0 6.1e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY67122.1 - 0.0043 16.2 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY67122.1 - 0.0048 16.2 0.0 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KEY67122.1 - 0.031 14.5 0.2 0.092 13.0 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY67122.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 KEY67123.1 - 7.3e-37 127.1 77.0 2.4e-33 115.5 50.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY67123.1 - 2.2e-05 23.5 39.8 0.0072 15.2 14.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Aldo_ket_red PF00248.21 KEY67124.1 - 2.2e-47 161.7 0.0 1.4e-45 155.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KEY67125.1 - 2.6e-40 138.0 0.1 3.7e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67125.1 - 3.3e-39 134.8 0.6 7.1e-39 133.7 0.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67125.1 - 3.7e-06 27.0 0.6 9.8e-06 25.6 0.5 1.7 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 KEY67125.1 - 0.029 14.2 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.11 KEY67125.1 - 0.037 13.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain NmrA PF05368.13 KEY67126.1 - 2.7e-12 46.7 0.3 3.6e-12 46.4 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY67126.1 - 4.5e-10 39.7 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY67126.1 - 9.2e-06 25.3 0.0 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KEY67126.1 - 0.00023 21.3 0.3 0.0007 19.7 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KEY67126.1 - 0.0003 20.7 0.1 0.00057 19.8 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 KEY67126.1 - 0.0031 17.7 0.2 0.0063 16.8 0.1 1.5 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KEY67126.1 - 0.0055 17.2 0.1 0.073 13.7 0.2 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KEY67126.1 - 0.0067 16.7 0.4 0.042 14.1 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 KEY67126.1 - 0.01 15.7 0.5 0.27 11.1 0.3 2.2 2 0 0 2 2 2 0 LpxI N-terminal domain Shikimate_DH PF01488.20 KEY67126.1 - 0.019 15.0 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_S13 PF00416.22 KEY67127.1 - 3.7e-56 189.0 2.9 4.3e-56 188.8 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KEY67127.1 - 0.017 13.9 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SBDS_C PF09377.10 KEY67128.1 - 1.5e-43 147.5 0.0 2.6e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KEY67128.1 - 3.6e-35 119.9 0.1 5.8e-35 119.2 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_1b PF00579.25 KEY67129.1 - 1.9e-22 79.9 0.2 6.2e-19 68.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DUF1713 PF08213.11 KEY67129.1 - 8.7 6.4 5.8 1 9.4 1.5 1.7 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1713) Peptidase_S10 PF00450.22 KEY67130.1 - 5e-126 421.5 0.5 5.9e-126 421.2 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KEY67130.1 - 1.7e-16 60.9 1.8 1.8e-15 57.6 1.8 2.2 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide ELO PF01151.18 KEY67131.1 - 2.3e-80 269.8 5.5 2.7e-80 269.5 5.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.21 KEY67132.1 - 4.6e-16 58.7 8.2 7.7e-16 58.0 8.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KEY67132.1 - 0.025 14.7 8.3 0.025 14.7 8.3 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger MoaC PF01967.21 KEY67133.1 - 1.9e-54 183.5 2.6 3.5e-54 182.6 2.6 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KEY67133.1 - 2.3e-37 127.8 0.0 2.4e-36 124.5 0.0 2.4 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KEY67133.1 - 2.4e-24 86.6 0.0 6.8e-24 85.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KEY67133.1 - 0.00016 22.0 0.0 0.00051 20.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Endostatin PF06482.11 KEY67133.1 - 0.045 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin IKI3 PF04762.12 KEY67134.1 - 0.024 12.6 0.0 2.1 6.3 0.0 2.9 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.12 KEY67134.1 - 1.2 9.2 3.8 19 5.3 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 KEY67135.1 - 4.6e-10 39.2 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GutM PF06923.11 KEY67135.1 - 0.25 11.5 0.1 0.65 10.1 0.1 1.6 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) HEAT_2 PF13646.6 KEY67137.1 - 3.1e-10 40.3 0.1 0.03 14.7 0.0 7.0 6 0 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KEY67137.1 - 4.4e-07 30.4 0.0 0.026 15.1 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEY67137.1 - 4.9e-07 29.9 0.0 0.13 12.3 0.0 5.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEY67137.1 - 0.00059 19.9 14.1 0.72 10.3 0.0 8.3 10 0 0 10 10 10 1 HEAT repeat CLASP_N PF12348.8 KEY67137.1 - 0.0027 17.3 0.5 12 5.4 0.0 4.6 4 0 0 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 KEY67137.1 - 0.0059 17.1 9.6 1.2 9.7 0.0 7.0 6 2 1 7 7 7 1 HEAT-like repeat UNC45-central PF11701.8 KEY67137.1 - 0.019 14.9 0.7 0.37 10.7 0.0 3.5 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 KEY67137.1 - 0.14 12.3 0.0 60 3.8 0.0 4.4 4 0 0 4 4 4 0 V-ATPase subunit H Arm PF00514.23 KEY67137.1 - 0.17 12.0 2.4 6.7 6.9 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Transcrip_reg PF01709.20 KEY67138.1 - 1.3e-61 208.1 0.0 1.5e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Flagellin_N PF00669.20 KEY67138.1 - 0.027 14.6 0.1 0.063 13.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Pet100 PF09803.9 KEY67139.1 - 4.7e-17 62.3 0.4 5.7e-17 62.0 0.4 1.1 1 0 0 1 1 1 1 Pet100 TMIE PF16038.5 KEY67139.1 - 0.036 13.9 0.4 0.046 13.6 0.4 1.1 1 0 0 1 1 1 0 TMIE protein HHH PF00633.23 KEY67141.1 - 0.025 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif NUDIX_2 PF13869.6 KEY67142.1 - 9e-78 260.2 0.0 1.1e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.17 KEY67143.1 - 4.3e-37 126.8 0.0 6.2e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 KEY67143.1 - 3.1e-16 59.1 1.2 5.2e-16 58.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 KEY67144.1 - 0.0001 22.8 10.0 0.025 15.1 9.9 2.9 1 1 0 1 1 1 1 M-phase phosphoprotein 6 CDC45 PF02724.14 KEY67144.1 - 0.81 7.9 13.1 1.4 7.1 13.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M16_M PF16187.5 KEY67145.1 - 4.3e-96 321.5 0.5 6.8e-96 320.8 0.5 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KEY67145.1 - 1.1e-33 116.3 0.1 2.8e-33 115.0 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEY67145.1 - 1.9e-30 106.3 0.0 1.9e-16 60.6 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain UCH PF00443.29 KEY67146.1 - 4.3e-68 229.6 0.0 6.1e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY67146.1 - 3.8e-13 49.7 0.0 2.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KEY67146.1 - 1.4e-09 38.4 0.0 5.2e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 KEY67146.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family PDEase_I PF00233.19 KEY67147.1 - 1.3e-64 218.2 0.0 1.9e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ADPRTs_Tse2 PF18648.1 KEY67147.1 - 0.095 12.7 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Tse2 ADP-ribosyltransferase toxins GMC_oxred_N PF00732.19 KEY67148.1 - 7.7e-40 137.1 0.9 1.2e-39 136.4 0.9 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY67148.1 - 2.6e-28 99.3 0.3 1.6e-27 96.8 0.1 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY67148.1 - 2e-07 30.5 0.7 2.1e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY67148.1 - 1.2e-06 28.0 0.8 2.6e-06 26.9 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY67148.1 - 1.3e-05 25.3 0.5 3.9e-05 23.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEY67148.1 - 0.00014 21.3 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY67148.1 - 0.00032 20.4 7.6 0.024 14.2 2.2 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY67148.1 - 0.00088 18.1 0.2 0.0014 17.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KEY67148.1 - 0.0099 15.3 0.5 0.014 14.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY67148.1 - 0.011 16.3 0.2 0.083 13.5 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY67148.1 - 0.04 13.1 0.1 0.04 13.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KEY67148.1 - 0.08 12.5 1.2 0.15 11.7 1.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KEY67148.1 - 0.11 11.7 0.1 1 8.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY67148.1 - 0.16 11.0 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NERD PF08378.11 KEY67149.1 - 0.089 13.3 0.2 0.33 11.4 0.1 1.8 2 0 0 2 2 2 0 Nuclease-related domain Glyco_transf_22 PF03901.17 KEY67151.1 - 8.6e-60 203.1 22.4 1e-59 202.9 22.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.19 KEY67152.1 - 1.4e-29 101.9 0.4 3.4e-29 100.7 0.4 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KEY67152.1 - 2.4e-22 78.8 0.2 5.9e-22 77.6 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 KEY67152.1 - 0.04 14.8 0.2 0.059 14.2 0.2 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Ribosomal_L39 PF00832.20 KEY67153.1 - 4.3e-22 77.5 9.5 4.9e-22 77.3 9.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Asp PF00026.23 KEY67154.1 - 9.6e-70 235.5 0.5 1.2e-69 235.1 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY67154.1 - 1.4e-15 58.0 0.4 3.5e-14 53.4 0.7 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY67154.1 - 4.3e-06 27.3 0.1 0.12 13.0 0.0 3.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KEY67154.1 - 6.1e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal PBP PF01161.20 KEY67155.1 - 1.6e-17 64.0 0.0 2.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2OG-FeII_Oxy_3 PF13640.6 KEY67156.1 - 2.8e-09 37.7 0.1 1.4e-08 35.5 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KEY67157.1 - 1.2e-11 44.1 0.0 4.1e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67157.1 - 1.5e-10 41.0 9.1 3e-10 40.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 KEY67158.1 - 1.6e-22 79.1 0.6 3.8e-22 77.9 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KEY67158.1 - 5.1e-09 35.9 1.3 1.1e-08 34.7 1.3 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KEY67158.1 - 0.0064 15.9 0.2 4.9 6.7 0.0 2.8 2 1 1 3 3 3 2 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KEY67159.1 - 2.8e-06 27.1 0.2 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain Rhodanese PF00581.20 KEY67159.1 - 1.8e-05 25.2 0.0 6.7e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain PIG-X PF08320.12 KEY67160.1 - 3.7e-70 236.1 0.0 6.4e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 AAA_2 PF07724.14 KEY67161.1 - 7.9e-47 159.6 0.0 3.3e-45 154.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KEY67161.1 - 4.4e-32 110.1 4.5 4.4e-32 110.1 4.5 3.9 4 0 0 4 4 3 1 AAA lid domain AAA PF00004.29 KEY67161.1 - 7.4e-27 94.4 0.0 1.8e-14 54.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KEY67161.1 - 3.9e-24 84.5 0.8 3.9e-24 84.5 0.8 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KEY67161.1 - 5.8e-16 58.7 0.0 5.2e-10 39.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY67161.1 - 3e-13 50.2 0.1 6.1e-05 23.3 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KEY67161.1 - 3.8e-11 43.7 12.5 1.4e-06 28.8 0.1 5.4 4 3 0 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KEY67161.1 - 6.3e-10 39.0 0.0 6.1e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 KEY67161.1 - 1.5e-06 28.3 0.0 0.081 13.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEY67161.1 - 3.1e-06 27.4 0.2 0.26 11.4 0.0 3.5 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KEY67161.1 - 3.7e-06 26.8 0.0 0.086 12.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KEY67161.1 - 4.6e-06 26.3 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KEY67161.1 - 5.3e-06 27.0 3.4 0.077 13.5 0.0 4.4 5 1 0 5 5 3 2 AAA domain Mg_chelatase PF01078.21 KEY67161.1 - 1.5e-05 24.5 0.1 0.21 10.9 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Clp_N PF02861.20 KEY67161.1 - 5.3e-05 23.3 4.0 0.00079 19.5 0.0 4.0 5 0 0 5 5 3 1 Clp amino terminal domain, pathogenicity island component RNA_helicase PF00910.22 KEY67161.1 - 5.8e-05 23.4 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KEY67161.1 - 6.3e-05 23.3 0.9 0.39 10.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 KEY67161.1 - 0.00014 21.6 1.7 1.9 8.2 0.7 4.5 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KEY67161.1 - 0.00017 21.5 0.0 0.91 9.4 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KEY67161.1 - 0.00021 21.1 0.0 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KEY67161.1 - 0.00024 21.1 9.4 0.048 13.6 0.1 5.2 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KEY67161.1 - 0.00027 20.7 0.0 0.38 10.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KEY67161.1 - 0.0003 20.8 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KEY67161.1 - 0.00041 20.3 0.7 0.38 10.6 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase AAA_19 PF13245.6 KEY67161.1 - 0.00046 20.5 0.4 0.17 12.2 0.3 3.6 4 1 0 4 4 2 1 AAA domain T2SSE PF00437.20 KEY67161.1 - 0.00063 18.9 0.2 0.016 14.2 0.1 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 KEY67161.1 - 0.00085 19.8 0.3 1.3 9.6 0.0 3.3 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 KEY67161.1 - 0.0016 18.4 0.0 0.23 11.4 0.0 3.2 3 0 0 3 3 2 1 NACHT domain Torsin PF06309.11 KEY67161.1 - 0.0035 17.4 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.15 KEY67161.1 - 0.0038 17.1 0.2 0.24 11.3 0.0 3.5 4 0 0 4 4 3 1 NTPase AAA_29 PF13555.6 KEY67161.1 - 0.0043 16.7 0.0 4.7 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 KEY67161.1 - 0.0051 16.8 0.3 5.6 6.8 0.0 3.4 3 1 0 3 3 3 0 Rad17 P-loop domain ResIII PF04851.15 KEY67161.1 - 0.0054 16.8 0.0 0.99 9.4 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 KEY67161.1 - 0.0073 16.5 0.0 2.3 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KEY67161.1 - 0.0077 15.5 0.0 1.2 8.3 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.22 KEY67161.1 - 0.033 13.8 0.0 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KEY67161.1 - 0.037 14.1 0.0 38 4.3 0.0 3.6 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KEY67161.1 - 0.039 13.5 3.4 1.9 8.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KEY67161.1 - 0.069 12.9 0.0 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KEY67161.1 - 0.074 13.6 16.1 0.37 11.3 0.0 4.3 3 1 0 3 3 2 0 AAA domain AAA_15 PF13175.6 KEY67161.1 - 0.098 12.3 1.3 30 4.1 0.5 3.5 4 0 0 4 4 3 0 AAA ATPase domain B2 PF11473.8 KEY67161.1 - 0.11 12.3 0.2 6.3 6.7 0.1 2.9 2 0 0 2 2 2 0 RNA binding protein B2 PduV-EutP PF10662.9 KEY67161.1 - 0.13 12.0 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 KEY67161.1 - 0.14 11.1 0.2 8.3 5.3 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 KEY67161.1 - 0.19 11.5 1.0 22 4.7 0.0 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system Macoilin PF09726.9 KEY67161.1 - 0.46 9.0 7.7 0.83 8.1 7.7 1.3 1 0 0 1 1 1 0 Macoilin family Nop16 PF09420.10 KEY67161.1 - 1.4 8.9 8.5 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 V_ATPase_I PF01496.19 KEY67161.1 - 3.6 5.4 8.8 7.3 4.4 8.8 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mhr1 PF12829.7 KEY67162.1 - 1e-32 112.1 0.0 2.1e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.6 KEY67163.1 - 3.5e-07 30.8 0.0 7.2e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family PDT PF00800.18 KEY67164.1 - 1.4e-60 204.3 0.0 1.7e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KEY67164.1 - 0.00039 20.1 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.25 KEY67165.1 - 8.6e-69 231.8 0.0 1.4e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67165.1 - 4.4e-49 167.1 0.0 7e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KEY67165.1 - 2.8e-27 95.0 0.0 5.1e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KEY67165.1 - 2.8e-16 59.4 0.1 5.9e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEY67165.1 - 2.2e-15 56.9 0.1 3.9e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KEY67165.1 - 2.1e-13 50.7 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KEY67165.1 - 3.5e-07 29.8 0.0 0.00072 19.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 KEY67165.1 - 0.025 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KEY67165.1 - 0.025 13.4 0.0 0.071 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SAM_PNT PF02198.16 KEY67165.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain GGACT PF06094.12 KEY67166.1 - 3.9e-07 30.7 0.1 5.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KEY67166.1 - 6.2e-06 26.5 0.1 1.2e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 AIG2-like family Wzy_C_2 PF11846.8 KEY67167.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal EBP PF05241.12 KEY67168.1 - 1.3e-56 190.9 10.7 1.5e-56 190.7 10.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein TetR_C_33 PF13305.6 KEY67168.1 - 0.022 15.5 0.8 0.035 14.9 0.1 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DHHC PF01529.20 KEY67168.1 - 0.92 9.6 6.5 3.8 7.6 2.0 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase HNOB PF07700.15 KEY67169.1 - 0.017 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding Nup88 PF10168.9 KEY67170.1 - 0.21 9.4 2.2 2.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore component RRM_1 PF00076.22 KEY67171.1 - 3.3e-16 58.8 0.0 5.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KEY67172.1 - 3.6e-45 152.6 0.5 4e-45 152.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.13 KEY67173.1 - 3.5e-39 133.9 0.0 1.3e-38 132.1 0.0 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KEY67173.1 - 0.021 14.7 0.0 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 Sybindin-like family CENP-T_C PF15511.6 KEY67174.1 - 9e-09 35.4 0.1 1.1e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KEY67174.1 - 2.6e-05 24.6 0.1 3.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KEY67174.1 - 8e-05 22.7 0.1 0.00012 22.2 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KEY67174.1 - 0.00022 21.5 0.1 0.00039 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KEY67174.1 - 0.00044 20.6 0.1 0.0006 20.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KEY67174.1 - 0.0093 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEY67174.1 - 0.034 14.1 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KEY67174.1 - 0.059 13.2 0.2 0.072 12.9 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KEY67174.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_1 PF00515.28 KEY67175.1 - 2.8e-32 109.2 18.1 2.3e-07 30.3 0.0 9.7 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY67175.1 - 1.1e-28 99.3 18.5 7.2e-22 77.4 0.8 4.7 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KEY67175.1 - 4.3e-28 95.1 23.4 2.2e-05 24.2 0.0 10.5 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KEY67175.1 - 7.3e-23 78.8 4.8 0.11 12.8 0.0 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEY67175.1 - 1e-22 80.4 10.3 1.7e-05 25.2 1.5 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY67175.1 - 2.2e-19 68.8 7.7 3.3e-07 29.9 0.4 8.1 6 2 3 9 9 9 4 TPR repeat TPR_7 PF13176.6 KEY67175.1 - 4.6e-16 57.6 8.0 0.00042 20.1 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67175.1 - 1.7e-14 53.3 21.1 0.071 14.0 0.1 10.0 4 2 7 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEY67175.1 - 1.7e-14 54.2 30.8 6.9e-10 39.4 0.2 7.9 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY67175.1 - 2.7e-14 52.4 12.2 0.61 10.6 0.2 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY67175.1 - 1.3e-13 51.0 17.7 0.056 13.7 0.3 7.7 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEY67175.1 - 1.2e-10 41.4 8.9 0.0031 17.6 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67175.1 - 3.7e-07 30.4 16.6 6.2 7.7 0.3 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 KEY67175.1 - 4.6e-06 26.0 14.2 0.0078 15.5 2.8 4.5 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 KEY67175.1 - 1.6e-05 25.1 1.9 0.096 13.0 0.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 KEY67175.1 - 0.0045 16.0 2.0 2 7.2 0.0 4.0 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 KEY67175.1 - 0.17 12.3 10.5 20 5.6 0.4 4.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KEY67175.1 - 3.7 7.6 15.8 40 4.2 0.6 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 KEY67176.1 - 2.3e-50 170.7 0.4 2.5e-50 170.5 0.4 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CPBP PF02517.16 KEY67176.1 - 0.028 14.8 1.6 6.1 7.3 0.4 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease DUF3605 PF12239.8 KEY67177.1 - 2.9e-58 196.6 0.0 3.4e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Chal_sti_synt_N PF00195.19 KEY67177.1 - 0.22 10.9 0.0 0.48 9.8 0.0 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Abhydrolase_3 PF07859.13 KEY67178.1 - 1.7e-20 73.8 0.0 2.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEY67178.1 - 5.2e-20 71.6 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Dmd PF17587.2 KEY67178.1 - 0.17 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Discriminator of mRNA degradation COesterase PF00135.28 KEY67178.1 - 0.18 10.7 1.1 4 6.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family CBFD_NFYB_HMF PF00808.23 KEY67179.1 - 5.8e-13 48.9 1.2 8.2e-13 48.4 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY67179.1 - 0.013 15.9 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF2630 PF10944.8 KEY67179.1 - 0.13 12.7 0.3 0.25 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) TAFII28 PF04719.14 KEY67179.1 - 0.16 12.1 1.0 0.31 11.1 1.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PI3_PI4_kinase PF00454.27 KEY67180.1 - 2.6e-33 115.9 0.0 7e-33 114.5 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KEY67180.1 - 6.2e-20 70.9 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KEY67180.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) zf-C3HC4_3 PF13920.6 KEY67181.1 - 0.00062 19.6 11.7 0.00097 18.9 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KEY67181.1 - 0.11 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 KEY67181.1 - 1.1 9.2 6.7 1.7 8.5 6.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ras PF00071.22 KEY67182.1 - 4.5e-58 195.4 0.0 5.4e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY67182.1 - 2.9e-34 117.8 0.0 4.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY67182.1 - 4.5e-14 52.3 0.0 7.1e-14 51.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY67182.1 - 4.1e-06 26.5 0.0 8.4e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEY67182.1 - 2.9e-05 23.5 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY67182.1 - 7.2e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY67182.1 - 0.00044 20.7 0.1 0.00079 19.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY67182.1 - 0.082 12.8 0.1 1.8 8.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KEY67182.1 - 0.14 12.4 0.0 1.3 9.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain Kri1 PF05178.12 KEY67183.1 - 3.7e-29 101.3 16.9 3.7e-29 101.3 16.9 5.0 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 KEY67183.1 - 9.9e-29 99.4 0.1 9.9e-29 99.4 0.1 3.5 4 0 0 4 4 4 1 KRI1-like family C-terminal DUF4381 PF14316.6 KEY67183.1 - 0.63 10.3 3.7 1.6 8.9 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YycI PF09648.10 KEY67183.1 - 2.4 7.7 6.0 0.45 10.1 2.0 1.7 2 0 0 2 2 2 0 YycH protein Fungal_trans PF04082.18 KEY67184.1 - 2.7e-29 102.0 0.0 4.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67184.1 - 2e-09 37.4 10.9 3.2e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C50 PF03568.17 KEY67185.1 - 1.6e-165 551.1 0.0 1.4e-164 547.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 KEY67185.1 - 0.0011 18.5 0.2 0.022 14.2 0.0 3.0 3 0 0 3 3 3 1 CHAT domain TPR_19 PF14559.6 KEY67185.1 - 0.0043 17.5 0.4 2.1 8.9 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY67185.1 - 0.0088 16.3 1.7 2.2 8.7 0.0 5.0 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67185.1 - 0.0097 16.7 13.3 1.2 10.2 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY67185.1 - 0.091 12.9 1.0 7.2 7.0 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY67185.1 - 1.2 9.4 3.6 16 5.8 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5321 PF17254.2 KEY67186.1 - 1.7e-58 196.6 3.2 2.2e-58 196.2 3.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF3708 PF12501.8 KEY67186.1 - 0.13 12.0 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter FUSC PF04632.12 KEY67186.1 - 1 7.8 2.6 1.4 7.4 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SIR2 PF02146.17 KEY67187.1 - 3.3e-30 105.3 0.0 5.5e-30 104.6 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KEY67189.1 - 1.3e-46 158.8 5.9 2e-46 158.2 5.9 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEY67189.1 - 2.5e-05 24.3 1.4 3.1e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter FGGY_C PF02782.16 KEY67190.1 - 1.3e-23 83.8 0.0 3.7e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEY67190.1 - 1.4e-20 73.9 0.0 3.7e-14 52.9 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cwf_Cwc_15 PF04889.12 KEY67191.1 - 6.2e-82 275.0 24.8 8.1e-82 274.7 24.8 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KEY67191.1 - 0.52 9.6 22.9 0.65 9.3 22.9 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KEY67191.1 - 0.8 9.1 28.6 1.1 8.7 28.6 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KEY67191.1 - 2.1 7.1 11.9 2.6 6.7 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KEY67191.1 - 8.8 5.0 8.1 11 4.7 8.1 1.1 1 0 0 1 1 1 0 Presenilin RNase_PH PF01138.21 KEY67192.1 - 8.3e-26 91.0 0.0 1.4e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEY67192.1 - 1.1e-09 38.1 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Arf PF00025.21 KEY67193.1 - 2.3e-40 137.9 0.0 3.6e-40 137.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEY67193.1 - 2.5e-14 53.2 0.0 1.3e-09 37.8 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KEY67193.1 - 5e-09 35.9 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KEY67193.1 - 9.1e-09 35.1 0.0 2.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY67193.1 - 9.4e-09 35.5 0.0 1.9e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEY67193.1 - 2e-07 30.7 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KEY67193.1 - 0.00034 20.2 0.0 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEY67193.1 - 0.00039 20.5 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KEY67193.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 NACHT domain Na_H_Exchanger PF00999.21 KEY67194.1 - 3.4e-74 249.9 42.4 4.1e-74 249.7 42.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 KEY67194.1 - 0.64 9.6 4.2 0.41 10.3 1.5 1.9 1 1 0 1 1 1 0 PepSY-associated TM region Myb_DNA-bind_6 PF13921.6 KEY67195.1 - 1.2e-15 57.5 0.3 1.2e-15 57.5 0.3 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KEY67195.1 - 1.3e-13 51.1 0.1 1.3e-13 51.1 0.1 3.7 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KEY67195.1 - 0.00011 22.4 0.2 0.00026 21.1 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fer2_3 PF13085.6 KEY67196.1 - 5.8e-32 109.9 0.0 9.7e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KEY67196.1 - 4.8e-09 36.6 7.7 4.8e-09 36.6 7.7 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEY67196.1 - 1.2e-08 34.9 3.1 1.2e-08 34.9 3.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEY67196.1 - 3.3e-08 33.8 27.0 1.2e-07 32.1 10.2 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KEY67196.1 - 0.0011 18.8 2.4 0.0036 17.2 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KEY67196.1 - 0.0021 18.6 8.1 0.0043 17.6 6.1 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KEY67196.1 - 0.0042 17.3 0.6 0.29 11.3 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEY67196.1 - 0.18 12.0 12.4 0.91 9.7 10.2 2.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain G-patch_2 PF12656.7 KEY67197.1 - 2.3e-19 69.2 1.2 2.3e-19 69.2 1.2 4.1 4 2 0 4 4 4 1 G-patch domain Phage_TTP_13 PF16463.5 KEY67197.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein family Kinetochor_Ybp2 PF08568.10 KEY67198.1 - 1.6e-97 327.5 0.0 2e-97 327.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rho_N PF07498.12 KEY67198.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DNApol_Exo PF18136.1 KEY67199.1 - 2.5e-105 351.7 0.0 4.6e-105 350.8 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KEY67199.1 - 8.5e-56 189.6 0.0 1.5e-55 188.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KEY67199.1 - 0.035 13.8 0.8 0.48 10.1 0.1 2.7 2 1 0 2 2 2 0 3'-5' exonuclease DUF1841 PF08897.11 KEY67199.1 - 0.039 14.0 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) zf-C3HC4_3 PF13920.6 KEY67200.1 - 6.8e-11 41.9 8.5 1e-10 41.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY67200.1 - 2.5e-07 30.4 8.3 4.6e-07 29.6 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEY67200.1 - 2.6e-06 27.2 11.8 4.3e-06 26.5 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67200.1 - 8.9e-06 25.9 9.8 1.5e-05 25.2 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEY67200.1 - 1e-05 25.3 10.7 1.7e-05 24.6 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY67200.1 - 1e-05 25.5 3.9 1e-05 25.5 3.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEY67200.1 - 4.5e-05 23.4 4.8 9.1e-05 22.4 4.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KEY67200.1 - 8.5e-05 22.4 10.3 0.00016 21.6 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KEY67200.1 - 0.004 16.9 5.5 0.0077 16.0 5.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RNHCP PF12647.7 KEY67200.1 - 0.0059 16.6 3.0 0.011 15.7 3.0 1.5 1 0 0 1 1 1 1 RNHCP domain zf-rbx1 PF12678.7 KEY67200.1 - 0.011 16.0 6.7 0.025 14.9 6.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KEY67200.1 - 0.051 13.7 8.5 0.089 13.0 8.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KEY67200.1 - 0.46 10.3 4.9 0.99 9.2 4.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KEY67200.1 - 2 8.6 8.8 1.7e+02 2.5 8.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Nup192 PF11894.8 KEY67201.1 - 0 1505.2 0.0 0 1504.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF4684 PF15736.5 KEY67201.1 - 0.045 12.4 0.1 0.085 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) PI3_PI4_kinase PF00454.27 KEY67202.1 - 1.7e-49 168.9 0.0 3.3e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KEY67202.1 - 1.9e-49 167.7 0.2 1.2e-48 165.1 0.0 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KEY67202.1 - 1.5e-11 43.9 0.0 4.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KEY67202.1 - 2.2e-08 33.7 2.9 2.2e-08 33.7 2.9 1.7 2 0 0 2 2 2 1 FAT domain Cnd1 PF12717.7 KEY67202.1 - 0.013 15.5 3.7 0.73 9.9 0.1 4.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TEBP_beta PF07404.11 KEY67202.1 - 0.076 12.4 0.6 0.15 11.4 0.6 1.4 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) ParD PF09386.10 KEY67202.1 - 0.08 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 Antitoxin ParD Cullin PF00888.22 KEY67203.1 - 6.1e-168 560.2 0.0 9.4e-168 559.6 0.0 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KEY67203.1 - 7.9e-26 89.9 0.4 2.3e-25 88.4 0.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain COesterase PF00135.28 KEY67204.1 - 1.1e-77 262.1 0.0 5.3e-77 259.8 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY67204.1 - 6.7e-10 39.2 0.2 5.3e-09 36.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY67204.1 - 0.094 12.2 0.8 0.16 11.4 0.8 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4614 PF15391.6 KEY67205.1 - 2 8.4 11.8 0.13 12.3 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 KEY67205.1 - 5.2 5.5 8.7 0.12 10.9 1.5 1.7 2 0 0 2 2 2 0 Macoilin family PIF1 PF05970.14 KEY67206.1 - 1e-60 205.8 0.1 1.8e-47 162.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KEY67206.1 - 1.2e-22 80.6 0.0 2.8e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY67206.1 - 2.5e-10 40.9 0.0 8e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY67206.1 - 1.6e-06 28.4 0.0 5.8e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEY67206.1 - 2.6e-06 27.1 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEY67206.1 - 8.8e-05 23.0 0.0 0.00035 21.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEY67206.1 - 0.00013 22.4 0.3 0.00059 20.3 0.0 2.3 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KEY67206.1 - 0.00018 21.3 0.1 0.00053 19.8 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KEY67206.1 - 0.00046 18.3 0.1 0.0014 16.7 0.0 1.6 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KEY67206.1 - 0.0008 19.2 0.1 0.31 10.8 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KEY67206.1 - 0.0015 19.1 0.3 0.0059 17.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KEY67206.1 - 0.0016 18.8 0.1 0.0056 17.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase T2SSE PF00437.20 KEY67206.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KEY67206.1 - 0.0063 16.6 0.0 0.032 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEY67206.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 KEY67206.1 - 0.0082 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein NB-ARC PF00931.22 KEY67206.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KEY67206.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KEY67206.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KEY67206.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KEY67206.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KEY67206.1 - 0.059 12.6 0.1 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KEY67206.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5605 PF18310.1 KEY67206.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) ATPase_2 PF01637.18 KEY67206.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pro_Al_protease PF02983.14 KEY67206.1 - 0.1 12.6 0.4 0.62 10.2 0.4 2.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Sigma54_activat PF00158.26 KEY67206.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KEY67206.1 - 0.22 11.4 0.1 0.67 9.8 0.1 1.8 2 0 0 2 2 1 0 NTPase YjeF_N PF03853.15 KEY67207.1 - 7.8e-38 130.0 0.0 1.2e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KEY67207.1 - 6.9e-09 36.5 0.9 6.9e-09 36.5 0.9 2.6 3 0 0 3 3 3 1 FDF domain PalH PF08733.10 KEY67208.1 - 1.1e-111 373.0 0.7 1.4e-111 372.7 0.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 DHHC PF01529.20 KEY67208.1 - 3.4 7.8 4.7 5.1 7.2 1.5 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase TRAM_LAG1_CLN8 PF03798.16 KEY67209.1 - 4.3e-38 131.1 20.5 6.5e-38 130.5 20.5 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KEY67209.1 - 1.9e-25 88.3 0.1 1.9e-25 88.3 0.1 2.1 3 0 0 3 3 3 1 TRAM1-like protein DUF4611 PF15387.6 KEY67209.1 - 0.0022 18.2 1.0 0.0044 17.2 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) FAM176 PF14851.6 KEY67209.1 - 0.082 12.6 0.5 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 KEY67209.1 - 7.6 4.7 7.0 13 3.9 5.9 1.7 2 0 0 2 2 2 0 CDC45-like protein p450 PF00067.22 KEY67210.1 - 1.8e-54 185.3 0.0 2.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tri3 PF07428.11 KEY67211.1 - 3.5e-91 306.1 0.0 4.5e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Cauli_VI PF01693.16 KEY67211.1 - 0.16 12.3 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin ketoacyl-synt PF00109.26 KEY67212.1 - 5.6e-70 235.8 0.0 1.1e-69 234.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEY67212.1 - 3.1e-49 167.8 0.0 4.8e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY67212.1 - 1e-46 160.0 0.0 2.2e-46 158.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY67212.1 - 1.4e-46 158.7 0.2 3.7e-46 157.3 0.2 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KEY67212.1 - 7e-38 129.3 0.1 6.7e-37 126.1 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY67212.1 - 1.4e-18 67.4 0.0 3.6e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY67212.1 - 1.3e-11 44.7 0.2 3.1e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KEY67212.1 - 1.9e-07 30.7 0.3 1.9e-07 30.7 0.3 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KEY67212.1 - 7.2e-06 25.9 0.0 3.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY67212.1 - 0.00011 22.9 0.1 0.0005 20.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEY67212.1 - 0.0028 17.1 0.1 0.0079 15.6 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KEY67212.1 - 0.0076 16.1 1.7 0.071 12.9 0.1 2.8 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.12 KEY67212.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 KEY67212.1 - 0.017 15.8 0.1 0.085 13.5 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 KEY67212.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_8 PF13523.6 KEY67213.1 - 6.3e-42 142.7 0.8 9e-42 142.2 0.8 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEY67213.1 - 0.022 15.5 0.2 0.056 14.1 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Tri3 PF07428.11 KEY67215.1 - 2.5e-34 118.9 0.0 3.1e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 HLH PF00010.26 KEY67217.1 - 7.2e-13 48.3 0.3 1.7e-12 47.1 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 KEY67217.1 - 0.01 16.0 2.2 0.15 12.1 2.2 2.4 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term CLTH PF10607.9 KEY67218.1 - 1.1e-32 113.0 0.0 1.6e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KEY67218.1 - 0.0024 17.8 0.8 0.01 15.8 0.0 2.4 3 0 0 3 3 3 1 LisH TrkA_N PF02254.18 KEY67218.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CAF1 PF04857.20 KEY67219.1 - 2.9e-21 76.0 0.0 5.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KEY67219.1 - 0.2 12.3 0.0 0.44 11.2 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain NDUF_B12 PF08122.12 KEY67220.1 - 1.9e-23 82.2 1.7 2.8e-23 81.7 1.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family SlyX PF04102.12 KEY67221.1 - 0.065 13.9 7.0 3 8.5 5.4 2.5 2 0 0 2 2 2 0 SlyX ThiF PF00899.21 KEY67223.1 - 5e-30 104.6 0.0 7.4e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family DUF5320 PF17253.2 KEY67224.1 - 0.074 14.1 8.9 0.13 13.4 6.8 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF2431 PF10354.9 KEY67225.1 - 6.1e-61 205.6 0.0 7.4e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) SRI PF08236.11 KEY67226.1 - 7.3e-22 77.4 5.1 2e-21 75.9 5.1 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KEY67226.1 - 7.8e-18 65.4 0.1 7.8e-18 65.4 0.1 3.3 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KEY67226.1 - 1.1e-11 44.5 6.4 1.1e-11 44.5 6.4 2.5 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KEY67226.1 - 1.3e-05 25.1 0.3 3.9e-05 23.6 0.3 1.9 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KEY67226.1 - 9e-05 22.4 0.3 9e-05 22.4 0.3 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain VIT1 PF01988.19 KEY67226.1 - 8.9 6.1 6.6 0.47 10.3 0.2 2.0 2 0 0 2 2 2 0 VIT family Aminotran_3 PF00202.21 KEY67228.1 - 1.5e-120 402.6 0.0 1.7e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEY67228.1 - 0.067 12.3 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Voltage_CLC PF00654.20 KEY67229.1 - 6.1e-89 298.7 27.8 6.8e-89 298.6 24.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel UCR_Fe-S_N PF10399.9 KEY67229.1 - 2.2 7.7 4.3 0.84 9.0 0.4 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sas10 PF09368.10 KEY67230.1 - 7.5e-30 103.2 7.5 7.5e-30 103.2 7.5 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KEY67230.1 - 6.9e-11 42.6 0.0 2.8e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DASH_Hsk3 PF08227.11 KEY67230.1 - 0.043 14.2 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Vps51 PF08700.11 KEY67231.1 - 2e-12 47.0 0.0 1.3e-11 44.4 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Glyco_hydro_18 PF00704.28 KEY67231.1 - 0.16 11.7 0.1 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 ECH_1 PF00378.20 KEY67232.1 - 1.5e-22 80.1 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY67232.1 - 3.3e-16 59.7 0.0 3.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RNA_pol_I_A49 PF06870.12 KEY67233.1 - 1.1e-97 327.3 0.3 1.4e-97 327.0 0.3 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 KEY67234.1 - 1.7e-54 184.9 0.0 2.4e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67234.1 - 1e-27 97.1 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEY67234.1 - 2.6e-12 46.9 0.0 5.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KEY67234.1 - 4.4e-06 26.2 0.0 1.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEY67234.1 - 6.7e-05 21.8 0.0 0.00017 20.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEY67234.1 - 0.00025 20.5 0.3 0.0012 18.3 0.0 1.9 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 KEY67234.1 - 5 5.7 6.7 7.5 5.1 6.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Zeta_toxin PF06414.12 KEY67235.1 - 3.7e-44 150.4 0.0 5.7e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KEY67235.1 - 2e-07 31.3 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KEY67235.1 - 0.00052 20.0 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KEY67235.1 - 0.024 13.6 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KEY67235.1 - 0.029 14.8 0.8 0.094 13.1 0.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY67235.1 - 0.038 14.3 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEY67235.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KEY67235.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DRAT PF07357.11 KEY67235.1 - 0.17 11.1 0.0 2.9 7.0 0.0 2.1 1 1 1 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) PduV-EutP PF10662.9 KEY67235.1 - 0.25 11.1 0.1 0.43 10.3 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zn_clus PF00172.18 KEY67236.1 - 0.0051 16.9 7.2 0.0085 16.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0506 PF11703.8 KEY67236.1 - 1.6 9.2 6.5 3.4 8.1 6.5 1.5 1 1 0 1 1 1 0 UPF0506 DUF3543 PF12063.8 KEY67237.1 - 4.9e-92 307.8 0.0 7.7e-92 307.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KEY67237.1 - 2.5e-61 207.4 0.0 4.9e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67237.1 - 1.2e-41 142.8 0.0 2.1e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KEY67237.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.21 KEY67238.1 - 1.5e-107 359.8 0.1 2.1e-104 349.4 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KEY67238.1 - 0.0025 17.2 0.0 0.0078 15.5 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 KEY67239.1 - 1.3e-78 265.2 22.4 1.6e-78 264.8 22.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.6 KEY67239.1 - 0.048 13.9 0.1 0.087 13.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) RhoGAP PF00620.27 KEY67240.1 - 7.5e-37 126.5 0.0 1.2e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.15 KEY67241.1 - 2.5e-19 68.7 1.5 4.7e-19 67.8 1.5 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Thionin PF00321.17 KEY67241.1 - 0.097 13.2 0.9 0.14 12.6 0.9 1.3 1 0 0 1 1 1 0 Plant thionin Nup188_C PF18378.1 KEY67242.1 - 6.6e-157 522.1 2.6 1.1e-156 521.4 2.6 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KEY67242.1 - 4.9e-43 147.2 0.0 4.7e-31 107.6 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KEY67243.1 - 3.5e-94 314.7 0.0 5e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KEY67243.1 - 8.5e-50 169.2 0.1 8e-45 153.0 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KEY67243.1 - 3.8e-46 157.3 0.0 1.8e-45 155.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEY67243.1 - 8.9e-06 25.6 0.1 3.2e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KEY67243.1 - 0.00076 19.3 0.3 0.063 13.1 0.1 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KEY67243.1 - 0.021 13.9 1.0 0.038 13.0 0.1 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Peripla_BP_2 PF01497.18 KEY67243.1 - 0.086 12.4 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein PTCB-BRCT PF12738.7 KEY67244.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 twin BRCT domain Use1 PF09753.9 KEY67245.1 - 1.4e-09 38.1 0.5 6.2e-09 35.9 0.5 2.0 1 1 1 2 2 2 1 Membrane fusion protein Use1 SPESP1 PF15754.5 KEY67245.1 - 0.0054 16.0 2.0 0.0079 15.4 2.0 1.2 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 KEY67245.1 - 0.055 13.4 6.3 0.1 12.5 6.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mto2_bdg PF12808.7 KEY67245.1 - 2.8 8.3 6.7 0.32 11.3 1.9 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region cwf21 PF08312.12 KEY67246.1 - 5e-17 61.8 16.2 5e-17 61.8 16.2 2.1 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.12 KEY67246.1 - 0.88 9.6 9.3 3.7 7.6 1.5 2.5 2 1 0 2 2 2 0 Gas vesicle protein G D123 PF07065.14 KEY67247.1 - 2.9e-117 391.2 0.0 3.3e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3716 PF12511.8 KEY67248.1 - 2.6e-15 56.2 8.3 4.1e-15 55.6 8.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) G-alpha PF00503.20 KEY67249.1 - 8.9e-121 403.4 3.2 1e-120 403.1 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEY67249.1 - 7.8e-13 48.2 1.2 2.9e-10 39.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KEY67249.1 - 0.00069 19.4 0.0 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger KTI12 PF08433.10 KEY67250.1 - 3.8e-73 246.3 0.0 6.2e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF1771 PF08590.10 KEY67250.1 - 1.8e-23 82.6 4.8 1.8e-23 82.6 4.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KEY67250.1 - 1.6e-11 44.4 0.5 1.5e-10 41.3 0.4 2.8 3 0 0 3 3 3 1 Smr domain AAA_33 PF13671.6 KEY67250.1 - 0.00021 21.5 0.6 0.00073 19.7 0.1 2.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KEY67250.1 - 0.02 15.4 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KEY67250.1 - 0.031 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KEY67250.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 KEY67250.1 - 0.099 13.0 0.2 0.42 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 KEY67251.1 - 2.7e-98 325.5 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY67251.1 - 3e-23 81.4 4.8 7.4e-13 48.1 0.3 3.0 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KEY67251.1 - 9.3e-19 67.4 0.4 3.6e-18 65.5 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KEY67251.1 - 1.4e-14 54.2 0.1 3.1e-06 27.0 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEY67251.1 - 9.1e-14 51.9 0.0 2.1e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEY67251.1 - 1.1e-13 51.9 0.0 0.00017 22.0 0.0 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 KEY67251.1 - 4.2e-12 46.4 0.0 4.6e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KEY67251.1 - 5.1e-12 46.0 0.4 3.4e-06 27.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY67251.1 - 1.5e-09 38.3 0.4 0.028 14.7 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KEY67251.1 - 3.3e-09 36.4 0.0 0.0011 18.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KEY67251.1 - 5.5e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KEY67251.1 - 2e-07 30.6 0.2 0.0068 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEY67251.1 - 2e-07 31.6 0.0 0.028 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KEY67251.1 - 3.3e-07 30.1 4.2 0.21 11.1 0.1 4.7 3 2 1 5 5 5 3 AAA domain IstB_IS21 PF01695.17 KEY67251.1 - 3.9e-07 30.0 0.0 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KEY67251.1 - 4.7e-07 29.7 0.4 4.4e-06 26.6 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 KEY67251.1 - 5.6e-07 29.9 0.0 0.031 14.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KEY67251.1 - 5.9e-07 29.1 0.2 0.25 10.7 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 KEY67251.1 - 6.5e-07 29.4 0.0 0.0081 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KEY67251.1 - 2.1e-06 27.4 0.0 0.036 13.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KEY67251.1 - 4.6e-06 26.5 0.0 0.082 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KEY67251.1 - 5e-06 25.9 0.0 0.0094 15.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KEY67251.1 - 8.4e-06 25.8 0.0 0.12 12.2 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein Parvo_NS1 PF01057.17 KEY67251.1 - 9.1e-06 24.9 0.1 0.051 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KEY67251.1 - 1.5e-05 25.3 0.0 0.17 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KEY67251.1 - 2e-05 24.4 0.1 0.23 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KEY67251.1 - 2.2e-05 25.0 0.0 0.28 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KEY67251.1 - 6.7e-05 22.9 0.0 0.41 10.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KEY67251.1 - 0.00013 22.0 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 KEY67251.1 - 0.00014 21.8 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KEY67251.1 - 0.00018 21.3 0.0 0.67 9.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KEY67251.1 - 0.00019 21.9 0.0 0.59 10.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KEY67251.1 - 0.00022 20.7 0.3 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KEY67251.1 - 0.00035 20.5 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEY67251.1 - 0.00044 20.0 0.3 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KEY67251.1 - 0.00063 19.7 0.0 1.8 8.4 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KEY67251.1 - 0.00099 19.5 0.4 5.6 7.3 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 KEY67251.1 - 0.0019 17.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KEY67251.1 - 0.0035 17.4 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KEY67251.1 - 0.0043 16.3 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 KEY67251.1 - 0.0048 16.8 0.6 2.5 8.0 0.0 3.9 4 0 0 4 4 3 1 NTPase Zeta_toxin PF06414.12 KEY67251.1 - 0.0075 15.6 0.7 7.8 5.7 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin Viral_helicase1 PF01443.18 KEY67251.1 - 0.0077 16.0 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 KEY67251.1 - 0.0095 15.2 0.4 0.85 8.8 0.0 3.3 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.16 KEY67251.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 KEY67251.1 - 0.032 13.7 0.0 0.17 11.3 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 KEY67251.1 - 0.051 13.2 0.0 2.4 7.8 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KEY67251.1 - 0.052 12.5 0.3 7.5 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KEY67251.1 - 0.056 13.2 0.0 9.9 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KEY67251.1 - 0.079 11.8 0.0 9.6 5.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase EnY2 PF10163.9 KEY67252.1 - 0.0036 17.6 0.0 0.014 15.8 0.0 1.8 2 0 0 2 2 2 1 Transcription factor e(y)2 ERAP1_C PF11838.8 KEY67252.1 - 0.021 14.3 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain NINJA_B PF16136.5 KEY67253.1 - 0.065 13.6 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal ABC_tran PF00005.27 KEY67254.1 - 1.6e-33 116.1 0.0 3.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEY67254.1 - 4.3e-27 95.4 4.3 4.3e-27 95.4 4.3 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KEY67254.1 - 5.8e-05 22.6 0.0 0.00089 18.7 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEY67254.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 KEY67254.1 - 0.0075 16.5 1.2 3 8.2 0.3 4.4 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KEY67254.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY67254.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_capsid PF06112.11 KEY67254.1 - 1.1 9.3 6.9 2.4 8.2 6.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IMUP PF15761.5 KEY67254.1 - 1.2 9.9 7.2 3.2 8.5 7.2 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_M14 PF00246.24 KEY67255.1 - 5.6e-73 246.3 0.0 7.6e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Git3 PF11710.8 KEY67256.1 - 2.3e-14 53.7 9.2 2.3e-14 53.7 9.2 2.0 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KEY67256.1 - 1.1e-08 34.8 2.1 1.1e-08 34.8 2.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KEY67256.1 - 0.0081 15.3 9.2 0.013 14.7 9.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KEY67256.1 - 0.014 15.4 1.0 0.035 14.2 0.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NPP1 PF05630.11 KEY67257.1 - 8.2e-57 192.5 1.2 9.5e-57 192.3 1.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Aldedh PF00171.22 KEY67258.1 - 1.3e-150 502.0 0.0 1.5e-150 501.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KEY67259.1 - 2e-53 181.7 0.0 2.8e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY67259.1 - 6.2e-40 137.0 0.0 9.5e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY67259.1 - 3.2e-05 23.2 0.0 0.082 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEY67259.1 - 6.1e-05 22.2 0.0 8.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY67259.1 - 0.00056 20.1 0.1 0.0017 18.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY67259.1 - 0.0058 15.9 0.0 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY67259.1 - 0.01 15.5 0.1 0.072 12.7 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY67259.1 - 0.059 13.9 0.1 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sirohm_synth_C PF14823.6 KEY67259.1 - 0.076 12.7 0.1 0.61 9.8 0.0 2.1 1 1 1 2 2 2 0 Sirohaem biosynthesis protein C-terminal Trp_halogenase PF04820.14 KEY67259.1 - 0.11 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KEY67259.1 - 0.25 10.0 0.0 0.52 8.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein DUF1479 PF07350.12 KEY67260.1 - 1.8e-141 471.7 0.0 2.5e-141 471.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) KIX PF02172.16 KEY67260.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 KIX domain Trp_oprn_chp PF09534.10 KEY67260.1 - 8 6.2 26.8 5.7 6.7 0.4 3.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SelP_N PF04592.14 KEY67260.1 - 8 5.8 18.2 18 4.7 18.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AMP-binding PF00501.28 KEY67261.1 - 7.6e-230 762.7 0.0 1.1e-76 258.1 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KEY67261.1 - 1.2e-173 578.0 0.0 1.5e-33 116.2 0.0 7.3 6 1 1 7 7 7 7 Condensation domain PP-binding PF00550.25 KEY67261.1 - 1.6e-52 175.7 19.9 6e-10 39.3 0.0 7.7 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEY67261.1 - 6.7e-14 52.6 0.0 0.0028 18.6 0.0 4.2 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KEY67261.1 - 3e-07 29.5 0.1 4.2 5.9 0.0 5.3 5 0 0 5 5 5 4 Transferase family WES_acyltransf PF03007.16 KEY67261.1 - 2.3e-05 24.3 0.4 2.6 7.7 0.0 4.8 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 KEY67262.1 - 8.6e-104 347.3 0.0 1.1e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEY67262.1 - 1.9e-05 24.1 0.1 0.0028 17.0 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY67262.1 - 5e-05 22.7 0.0 0.0038 16.5 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY67262.1 - 0.0033 17.4 0.1 0.082 12.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Malic_M PF03949.15 KEY67262.1 - 0.22 10.8 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain IF-2B PF01008.17 KEY67263.1 - 3.1e-21 75.8 0.0 4.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.18 KEY67263.1 - 4.8e-12 45.5 0.0 1.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.28 KEY67263.1 - 2.7e-10 40.4 0.0 8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Zn_clus PF00172.18 KEY67263.1 - 1.1e-05 25.5 8.7 1.8e-05 24.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FF PF01846.19 KEY67264.1 - 2.4e-13 50.0 8.1 2.5e-09 37.1 0.2 2.8 3 0 0 3 3 3 2 FF domain WW PF00397.26 KEY67264.1 - 1.4e-08 34.7 0.4 3.2e-08 33.5 0.4 1.7 1 0 0 1 1 1 1 WW domain DUF5641 PF18701.1 KEY67264.1 - 0.0036 17.4 0.9 0.013 15.7 0.5 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5641) TTSSLRR PF12468.8 KEY67264.1 - 0.12 12.6 1.0 0.36 11.1 1.0 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein VGLL4 PF15245.6 KEY67264.1 - 2 8.5 5.5 0.19 11.8 0.4 1.9 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 PAP2 PF01569.21 KEY67265.1 - 1.4e-28 99.4 1.1 3.1e-28 98.2 1.1 1.6 1 0 0 1 1 1 1 PAP2 superfamily Glucos_trans_II PF14264.6 KEY67265.1 - 0.025 13.9 2.3 0.057 12.8 2.3 1.6 1 0 0 1 1 1 0 Glucosyl transferase GtrII PAP2_3 PF14378.6 KEY67265.1 - 0.029 14.1 7.0 0.49 10.0 7.0 2.3 1 1 0 1 1 1 0 PAP2 superfamily Proteasome PF00227.26 KEY67266.1 - 4.9e-61 205.6 0.1 5.9e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEY67266.1 - 8.3e-14 51.0 0.1 8.7e-13 47.7 0.1 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KEY67266.1 - 0.015 15.4 0.5 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KEY67266.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Ferric_reduct PF01794.19 KEY67267.1 - 7.3e-19 68.1 13.7 1.4e-18 67.2 13.7 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEY67267.1 - 4.5e-07 29.9 0.1 9.4e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KEY67267.1 - 0.00021 21.8 14.4 0.033 14.7 0.8 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) HMW1C_N PF18071.1 KEY67267.1 - 2.9 7.7 5.4 17 5.2 1.9 2.2 2 0 0 2 2 2 0 HMW1C N-terminal Peptidase_C2 PF00648.21 KEY67269.1 - 2.8e-28 98.8 0.0 4.2e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KEY67269.1 - 1.5e-08 35.0 0.0 1.6e-05 25.2 0.0 3.3 2 1 0 2 2 2 1 Calpain large subunit, domain III Mito_carr PF00153.27 KEY67270.1 - 5.4e-55 183.3 0.9 1.2e-19 70.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KEY67270.1 - 0.032 14.4 0.1 23 5.2 0.0 3.3 3 0 0 3 3 3 0 PrcB C-terminal Ribosomal_L29e PF01779.17 KEY67271.1 - 4.3e-22 78.1 8.9 6.4e-22 77.6 8.9 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Stealth_CR1 PF17101.5 KEY67271.1 - 0.063 13.0 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 SAM_2 PF07647.17 KEY67272.1 - 3.3e-09 36.7 0.1 6.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEY67272.1 - 7.2e-05 23.1 0.2 0.00015 22.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KEY67272.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif DUF4508 PF14969.6 KEY67272.1 - 0.098 12.9 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_2 PF07719.17 KEY67273.1 - 9.5e-12 44.1 19.0 0.28 11.4 0.0 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67273.1 - 6.2e-11 42.2 23.6 0.046 14.6 0.2 10.1 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY67273.1 - 7.3e-11 41.4 3.0 2.2 8.2 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY67273.1 - 2.1e-10 41.1 25.8 0.0014 19.2 0.0 7.1 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY67273.1 - 9.9e-10 38.8 14.9 0.0027 18.2 0.1 7.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY67273.1 - 2.7e-08 33.4 7.4 0.058 13.6 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY67273.1 - 3.9e-08 32.8 7.7 0.057 13.5 0.1 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY67273.1 - 1.3e-06 28.3 2.5 7.4 7.2 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEY67273.1 - 1.5e-06 27.8 0.8 0.35 10.6 0.0 6.1 6 1 1 7 7 7 2 TPR repeat TPR_20 PF14561.6 KEY67273.1 - 8.1e-06 26.1 14.5 0.32 11.3 0.0 6.8 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY67273.1 - 0.0067 16.7 27.2 0.067 13.5 0.1 7.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67273.1 - 0.015 15.9 12.1 2.3 9.0 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KEY67273.1 - 0.13 12.7 0.8 13 6.3 0.1 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation NARP1 PF12569.8 KEY67273.1 - 0.27 10.1 2.1 4 6.2 0.0 2.6 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KEY67273.1 - 2.6 8.2 16.0 2 8.6 0.4 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat Sad1_UNC PF07738.13 KEY67274.1 - 6e-33 113.7 0.0 9.6e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Macoilin PF09726.9 KEY67274.1 - 0.018 13.7 7.2 0.036 12.7 7.2 1.4 1 0 0 1 1 1 0 Macoilin family RRM_2 PF04059.12 KEY67275.1 - 2.5e-39 133.4 0.6 5.6e-39 132.3 0.3 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 KEY67275.1 - 0.0093 15.8 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 KEY67276.1 - 9.9e-111 370.1 3.2 9.9e-111 370.1 3.2 2.2 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 KEY67276.1 - 0.0083 15.9 5.5 0.0089 15.8 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) YjbF PF11102.8 KEY67276.1 - 0.052 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Spc29 PF17082.5 KEY67276.1 - 0.29 11.0 7.0 0.12 12.2 2.5 2.6 4 0 0 4 4 4 0 Spindle Pole Component 29 Hrs_helical PF12210.8 KEY67276.1 - 0.49 11.0 10.9 3.3 8.3 0.3 3.3 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3510 PF12022.8 KEY67276.1 - 0.57 10.6 6.8 4.3 7.7 0.1 3.9 3 2 2 5 5 5 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 KEY67276.1 - 2.9 7.8 13.9 0.043 13.7 1.6 4.0 5 0 0 5 5 5 0 Sec8 exocyst complex component specific domain CBFD_NFYB_HMF PF00808.23 KEY67277.1 - 2.5e-19 69.3 0.5 4e-19 68.7 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY67277.1 - 4.1e-16 59.5 0.2 7.5e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KEY67277.1 - 0.041 14.2 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 KEY67277.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fcf2 PF08698.11 KEY67278.1 - 1.9e-28 98.7 0.7 1.9e-28 98.7 0.7 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.22 KEY67279.1 - 3.3e-24 85.0 0.0 5.4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 KEY67280.1 - 2.7e-54 184.5 0.0 1.6e-52 178.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 KEY67280.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Importin_rep_3 PF18806.1 KEY67281.1 - 0.031 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Importin 13 repeat Importin_rep PF18773.1 KEY67281.1 - 0.033 13.9 0.0 0.096 12.4 0.0 1.9 1 0 0 1 1 1 0 Importin 13 repeat Creatinase_N_2 PF16189.5 KEY67282.1 - 8.9e-52 175.4 0.0 4.7e-50 169.8 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KEY67282.1 - 7.1e-41 140.2 0.1 1.1e-40 139.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KEY67282.1 - 1.9e-23 82.3 0.0 4.9e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KEY67282.1 - 1.8e-20 73.9 0.1 6e-17 62.5 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Histone PF00125.24 KEY67283.1 - 6.7e-41 139.7 0.4 9.7e-41 139.2 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KEY67283.1 - 3.2e-06 27.2 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KEY67283.1 - 0.00063 20.1 0.0 0.00091 19.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KEY67283.1 - 0.00072 19.6 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KEY67283.1 - 0.0038 17.5 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.15 KEY67284.1 - 6.8e-51 172.9 4.9 7.8e-51 172.7 4.9 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 KEY67285.1 - 1e-45 155.7 0.0 1.2e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KEY67285.1 - 4.2e-08 32.8 0.1 7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEY67285.1 - 3.8e-06 26.8 0.0 5.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain SH3_16 PF18348.1 KEY67285.1 - 0.035 13.9 0.4 0.075 12.8 0.4 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain adh_short PF00106.25 KEY67286.1 - 3.7e-29 101.6 0.0 5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67286.1 - 4.5e-20 72.2 0.0 6.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67286.1 - 1.2e-09 38.4 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY67286.1 - 2.5e-07 30.4 0.1 4.9e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY67286.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEY67286.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY67286.1 - 0.089 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEY67286.1 - 0.2 11.1 0.1 0.4 10.2 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family EamA PF00892.20 KEY67287.1 - 0.00093 19.4 9.5 0.00093 19.4 9.5 2.3 2 0 0 2 2 2 1 EamA-like transporter family Spike_rec_bind PF09408.10 KEY67287.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Spike receptor binding domain UPF0370 PF13980.6 KEY67287.1 - 0.036 14.1 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) MBOAT PF03062.19 KEY67288.1 - 2.2e-55 188.4 3.9 4.2e-55 187.5 3.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CPBP PF02517.16 KEY67290.1 - 1.2e-14 54.4 10.0 1.6e-14 54.0 7.5 2.2 1 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF3323 PF11796.8 KEY67290.1 - 0.043 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) MMM1 PF10296.9 KEY67291.1 - 9.9e-141 468.6 0.2 3.2e-139 463.6 0.2 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Pilin_N PF07790.11 KEY67291.1 - 0.06 14.3 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Peptidase_M73 PF12389.8 KEY67291.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Sec1 PF00995.23 KEY67292.1 - 8.6e-136 454.5 0.0 9.9e-136 454.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GIDA PF01134.22 KEY67293.1 - 3.6e-155 516.9 0.0 4.7e-155 516.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KEY67293.1 - 6.4e-64 216.0 0.0 9e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KEY67293.1 - 7.3e-07 28.7 0.2 1.3e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY67293.1 - 9.1e-07 28.6 0.5 1.4e-06 27.9 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY67293.1 - 0.00051 19.2 2.1 0.00051 19.2 2.1 2.4 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEY67293.1 - 0.012 14.9 0.1 0.012 14.9 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEY67293.1 - 0.014 14.1 5.0 0.076 11.7 1.0 3.1 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KEY67293.1 - 0.035 14.1 1.0 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KEY67293.1 - 0.067 12.8 1.3 4.3 6.8 0.6 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEY67293.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KEY67293.1 - 0.14 11.0 0.3 16 4.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase CDP-OH_P_transf PF01066.21 KEY67294.1 - 2.8e-15 56.9 0.4 2.8e-15 56.9 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WD40 PF00400.32 KEY67295.1 - 7.4e-60 197.5 14.2 2e-08 34.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KEY67295.1 - 4.1e-17 62.2 10.8 7.4e-17 61.4 10.8 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KEY67295.1 - 1.1e-15 57.6 0.0 0.00021 21.5 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY67295.1 - 3.6e-07 29.4 0.4 0.46 9.4 0.0 5.0 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY67295.1 - 4.5e-07 29.5 0.0 0.053 12.8 0.0 4.8 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 KEY67295.1 - 1.6e-05 23.8 1.7 0.025 13.3 0.0 4.1 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEY67295.1 - 0.0011 17.6 0.1 0.049 12.1 0.0 2.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain SHE3 PF17078.5 KEY67295.1 - 0.015 15.0 1.6 0.022 14.5 1.6 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PQQ_3 PF13570.6 KEY67295.1 - 0.092 13.3 0.4 14 6.3 0.3 3.5 3 0 0 3 3 3 0 PQQ-like domain MMS1_N PF10433.9 KEY67295.1 - 0.12 11.0 0.0 0.42 9.2 0.0 1.8 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 KEY67295.1 - 0.12 11.7 0.1 18 4.6 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Golgin_A5 PF09787.9 KEY67295.1 - 0.19 11.1 5.0 0.28 10.6 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPX2 PF06886.11 KEY67295.1 - 0.38 11.0 6.1 2.6 8.3 6.1 2.0 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) TSNAXIP1_N PF15739.5 KEY67295.1 - 1.7 9.0 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus CAP_N PF01213.19 KEY67296.1 - 0.1 12.1 8.6 0.094 12.2 7.5 1.5 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aa_trans PF01490.18 KEY67297.1 - 5.2e-60 203.3 20.0 6.4e-60 203.0 20.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEY67297.1 - 0.0008 18.5 7.2 0.0008 18.5 7.2 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 KEY67298.1 - 1.9e-56 191.3 0.0 3.1e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67298.1 - 4.4e-35 121.2 0.0 6.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY67298.1 - 3e-14 53.0 0.0 2.1e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEY67298.1 - 0.0081 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY67298.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4078 PF13300.6 KEY67298.1 - 0.33 11.3 2.9 0.82 10.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Bmt2 PF11968.8 KEY67301.1 - 2e-83 279.6 0.0 2.9e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KEY67301.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L23eN PF03939.13 KEY67302.1 - 1.8e-27 95.3 9.0 1.8e-27 95.3 9.0 2.4 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KEY67302.1 - 1e-14 54.7 0.7 2.3e-14 53.5 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 KEY67303.1 - 2.5e-17 62.3 3.2 3.3e-17 61.9 3.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PheRS_DBD2 PF18554.1 KEY67303.1 - 0.047 13.7 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Tyr-DNA_phospho PF06087.12 KEY67304.1 - 3.5e-83 279.9 0.0 4.1e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KEY67304.1 - 0.00059 19.6 5.3 0.0015 18.3 5.3 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KEY67304.1 - 0.0038 17.1 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 KEY67305.1 - 7.8e-63 211.8 0.0 1.1e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family KRTAP PF11759.8 KEY67305.1 - 0.11 13.1 8.9 0.22 12.1 8.9 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 KEY67305.1 - 0.65 10.1 14.1 0.04 14.1 8.4 1.8 2 0 0 2 2 2 0 Keratin type II head DUF2015 PF09435.10 KEY67306.1 - 2e-46 156.5 0.0 2.3e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 KEY67307.1 - 1e-34 119.7 0.4 1.4e-34 119.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 KEY67308.1 - 7.1e-46 156.2 0.0 1.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEY67308.1 - 1.5e-42 145.1 0.2 2.1e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEY67308.1 - 0.0017 17.4 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEY67308.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEY67308.1 - 0.022 15.2 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 KEY67308.1 - 0.11 12.1 0.1 4.1 6.9 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.16 KEY67309.1 - 2e-40 137.9 0.0 6.3e-40 136.3 0.0 1.8 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3235 PF11574.8 KEY67309.1 - 0.02 15.8 0.1 0.032 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Prog_receptor PF02161.15 KEY67309.1 - 0.13 11.0 2.8 0.18 10.5 2.8 1.1 1 0 0 1 1 1 0 Progesterone receptor PINIT PF14324.6 KEY67310.1 - 5.5e-41 140.3 0.1 1.3e-40 139.1 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KEY67310.1 - 1.2e-20 72.9 8.9 2.1e-20 72.2 8.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KEY67310.1 - 1.4e-05 24.8 3.0 3.1e-05 23.7 3.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KEY67310.1 - 6.2e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 KEY67310.1 - 0.027 14.5 2.3 0.08 13.0 2.3 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger TFIIF_alpha PF05793.12 KEY67310.1 - 0.29 9.7 2.2 0.52 8.8 2.1 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-RING_5 PF14634.6 KEY67310.1 - 6 6.9 6.9 12 5.9 6.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CorA PF01544.18 KEY67311.1 - 3.5e-45 154.6 0.0 6.3e-45 153.7 0.0 1.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 KEY67312.1 - 2.5e-26 91.5 0.2 2.9e-26 91.3 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KEY67312.1 - 0.0079 16.5 0.7 0.01 16.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) zf-rbx1 PF12678.7 KEY67313.1 - 2.6e-24 85.3 13.4 3.8e-24 84.7 13.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEY67313.1 - 1.2e-15 57.3 9.9 1.7e-15 56.8 9.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEY67313.1 - 9.2e-06 25.9 15.3 0.00039 20.7 15.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEY67313.1 - 4.6e-05 23.2 2.7 4.6e-05 23.2 2.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY67313.1 - 0.002 18.0 11.7 0.064 13.1 11.7 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY67313.1 - 0.4 10.7 6.9 1.4 9.0 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KEY67313.1 - 0.63 9.8 16.3 51 3.7 16.3 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KEY67313.1 - 0.97 9.3 11.1 2.2 8.2 4.9 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KEY67313.1 - 2.3 8.5 9.6 14 5.9 9.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KEY67313.1 - 5.6 6.7 16.0 0.69 9.6 5.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 KEY67314.1 - 2.7e-08 33.4 7.3 2.7e-08 33.4 7.3 4.9 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif Phosphodiest PF01663.22 KEY67315.1 - 5e-14 52.6 0.4 2.6e-10 40.4 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEY67315.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KEY67315.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cnd3 PF12719.7 KEY67316.1 - 7.8e-91 304.3 3.3 5.3e-90 301.6 1.5 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KEY67316.1 - 7e-11 42.4 12.2 6.5e-07 29.6 2.0 5.1 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KEY67316.1 - 3.2e-07 30.0 10.8 0.079 13.3 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 KEY67316.1 - 0.00014 22.0 5.8 0.3 11.1 0.1 5.1 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 RRM_1 PF00076.22 KEY67317.1 - 4.4e-61 202.6 1.1 3.6e-19 68.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KEY67317.1 - 1.5e-07 31.8 1.5 0.76 10.0 0.0 5.9 4 4 2 6 6 6 3 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KEY67317.1 - 6.4e-06 26.2 0.1 1.4 9.1 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif RRM_Rrp7 PF17799.1 KEY67317.1 - 4.4e-05 23.4 0.2 0.098 12.5 0.0 3.7 3 1 1 4 4 4 2 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 KEY67317.1 - 0.028 14.4 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain Mg_trans_NIPA PF05653.14 KEY67319.1 - 1.4e-57 195.0 7.4 3.7e-55 187.1 4.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KEY67319.1 - 7e-05 23.0 24.4 0.0037 17.5 1.4 4.0 3 1 1 4 4 4 2 EamA-like transporter family SLC35F PF06027.12 KEY67319.1 - 0.046 13.2 6.8 0.068 12.7 0.4 2.3 1 1 0 2 2 2 0 Solute carrier family 35 Phage_holin_2_3 PF16080.5 KEY67319.1 - 0.062 13.1 0.7 0.34 10.7 0.7 2.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Ctr PF04145.15 KEY67319.1 - 0.071 13.7 0.0 1.9 9.1 0.0 2.7 2 1 1 3 3 3 0 Ctr copper transporter family DUF2569 PF10754.9 KEY67319.1 - 0.42 11.1 5.3 0.2 12.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF1461 PF07314.11 KEY67319.1 - 0.81 9.6 5.2 0.61 10.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF4149 PF13664.6 KEY67319.1 - 2.8 8.3 12.1 0.68 10.3 0.4 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) TssN PF17555.2 KEY67319.1 - 3.5 6.9 9.2 8.7 5.6 9.4 1.5 1 1 1 2 2 2 0 Type VI secretion system, TssN PBD PF00786.28 KEY67321.1 - 0.029 14.7 0.9 0.15 12.5 0.5 2.4 2 0 0 2 2 2 0 P21-Rho-binding domain Pns11_12 PF17464.2 KEY67321.1 - 1.7 8.3 7.4 4.2 7.0 5.0 2.2 2 0 0 2 2 2 0 Non-structural protein 11 and 12 POB3_N PF17292.2 KEY67322.1 - 1.2e-31 108.9 0.5 5.7e-30 103.6 0.3 2.7 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KEY67322.1 - 6.3e-29 99.7 0.1 1.3e-27 95.5 0.0 3.1 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KEY67322.1 - 7.2e-22 77.6 0.0 4.8e-21 75.0 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 KEY67322.1 - 0.13 12.6 0.0 1.9 8.9 0.0 2.6 3 0 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain Lipase_3 PF01764.25 KEY67323.1 - 7.9e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY67323.1 - 0.023 15.3 0.3 0.023 15.3 0.3 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY67323.1 - 0.032 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KEY67323.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) YL1 PF05764.13 KEY67324.1 - 5.1e-72 242.9 32.0 5.1e-72 242.9 32.0 3.2 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 KEY67324.1 - 1.7e-15 56.5 1.6 3.8e-15 55.4 1.6 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 KEY67324.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger AMPK1_CBM PF16561.5 KEY67325.1 - 0.05 13.8 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase FA_hydroxylase PF04116.13 KEY67326.1 - 1.5e-23 83.6 15.2 1.8e-23 83.3 12.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.17 KEY67327.1 - 2.3e-71 239.5 1.3 2.5e-71 239.3 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Feld-I_B PF09252.10 KEY67327.1 - 0.16 11.9 0.2 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Allergen Fel d I-B chain AIM3 PF17096.5 KEY67328.1 - 0.0051 17.7 0.1 0.0051 17.7 0.1 3.9 4 1 0 4 4 4 1 Altered inheritance of mitochondria protein 3 Mis12 PF05859.12 KEY67329.1 - 1.4e-45 154.6 0.0 2.5e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein UreF PF01730.16 KEY67329.1 - 0.0054 17.3 0.2 0.012 16.2 0.2 1.5 1 0 0 1 1 1 1 UreF PPR_2 PF13041.6 KEY67330.1 - 7e-20 71.0 0.0 0.00014 22.0 0.0 6.5 6 1 2 8 8 8 6 PPR repeat family PPR_3 PF13812.6 KEY67330.1 - 8.2e-17 61.0 0.0 0.0043 17.1 0.0 6.6 5 2 1 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.20 KEY67330.1 - 5.7e-10 38.8 0.0 0.11 12.8 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 KEY67330.1 - 1.4e-07 31.1 0.0 0.19 11.5 0.0 4.6 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KEY67330.1 - 5.3e-06 26.0 0.0 0.45 9.9 0.1 3.6 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KEY67330.1 - 0.00068 20.0 0.0 0.26 11.7 0.0 3.7 3 1 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) DUF832 PF05734.11 KEY67330.1 - 0.059 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) TPR_16 PF13432.6 KEY67330.1 - 0.78 10.4 3.2 0.97 10.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_N PF02798.20 KEY67331.1 - 7e-11 42.3 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY67331.1 - 3.1e-07 30.7 0.0 6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY67331.1 - 8.9e-06 25.8 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEY67331.1 - 3.4e-05 24.0 0.0 0.00026 21.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY67331.1 - 6e-05 23.2 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY67331.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Alg6_Alg8 PF03155.15 KEY67332.1 - 4.3e-175 583.3 25.8 5.3e-175 583.0 25.8 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 KEY67332.1 - 9.4e-39 132.0 2.0 3e-38 130.4 0.1 2.6 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KEY67332.1 - 1e-16 61.2 2.4 1.8e-16 60.4 0.0 2.5 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KEY67332.1 - 5e-15 55.5 1.0 1.1e-14 54.5 1.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KEY67332.1 - 2.9e-07 29.9 0.0 7.2e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Lectin_leg-like PF03388.13 KEY67333.1 - 8.9e-25 87.4 0.0 2.4e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Legume-like lectin family DUF5523 PF17661.1 KEY67333.1 - 0.00071 19.3 2.4 0.00071 19.3 2.4 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5523) BLOC1_2 PF10046.9 KEY67333.1 - 0.03 14.6 5.3 0.056 13.7 5.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KEY67333.1 - 0.082 12.9 4.1 0.3 11.1 4.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 KEY67333.1 - 0.32 10.8 1.0 27 4.7 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF2730 PF10805.8 KEY67333.1 - 0.36 11.0 3.1 0.9 9.7 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) FUSC PF04632.12 KEY67333.1 - 0.41 9.1 0.9 0.53 8.8 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TSC22 PF01166.18 KEY67333.1 - 0.85 10.0 4.0 0.41 11.0 0.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 KEY67333.1 - 0.92 9.0 6.7 1.3 8.5 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 KEY67333.1 - 1.2 9.4 8.6 1.9 8.8 3.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 KEY67333.1 - 1.2 9.5 5.1 3.5 7.9 0.1 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain DASH_Hsk3 PF08227.11 KEY67333.1 - 1.8 9.0 5.4 14 6.1 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Phage_GPO PF05929.11 KEY67333.1 - 2.2 7.9 10.2 0.53 9.8 6.5 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Tmemb_cc2 PF10267.9 KEY67333.1 - 3.9 6.5 17.9 0.57 9.3 1.1 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CSN5_C PF18323.1 KEY67333.1 - 8.9 7.3 12.8 23 6.0 0.3 3.2 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Peptidase_M24 PF00557.24 KEY67334.1 - 2.8e-58 197.0 0.1 3.7e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEY67334.1 - 8.7e-19 67.5 0.0 1.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.18 KEY67335.1 - 2e-28 99.2 0.1 3e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67335.1 - 9.3e-11 41.7 13.6 1.8e-10 40.7 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KEY67335.1 - 2.1 8.3 7.7 5.5 6.9 7.7 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPN7 PF10602.9 KEY67336.1 - 2.6e-46 157.5 0.0 4.4e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KEY67336.1 - 2.4e-17 63.3 0.1 1.4e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KEY67336.1 - 0.006 16.6 0.2 24 5.3 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Prp18 PF02840.15 KEY67337.1 - 1e-53 181.2 0.0 1e-53 181.2 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KEY67337.1 - 1e-11 44.1 2.2 1e-11 44.1 2.2 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Borrelia_P83 PF05262.11 KEY67337.1 - 2.1 6.8 13.3 2.8 6.3 13.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.10 KEY67337.1 - 5.5 6.3 20.4 0.27 10.6 15.1 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 NDUF_B4 PF07225.12 KEY67338.1 - 0.065 13.1 0.1 0.069 13.0 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PROCN PF08083.11 KEY67339.1 - 1.7e-233 774.6 9.1 1.7e-233 774.6 9.1 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KEY67339.1 - 1.9e-126 420.3 1.2 3.6e-126 419.4 1.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KEY67339.1 - 1.5e-84 281.7 0.9 2.3e-57 193.4 0.1 2.9 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KEY67339.1 - 3.6e-78 260.8 2.9 3.6e-78 260.8 2.9 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KEY67339.1 - 4.1e-71 237.3 0.1 9e-71 236.2 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KEY67339.1 - 1.8e-46 156.4 0.2 2.1e-45 153.0 0.1 2.7 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KEY67339.1 - 3e-42 143.4 0.4 8.4e-42 142.0 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 KEY67339.1 - 5.4e-09 36.3 0.0 6e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Hom_end-associated Hint JAB PF01398.21 KEY67339.1 - 0.028 14.4 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cyt-b5 PF00173.28 KEY67340.1 - 4e-12 46.1 0.0 5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CytB6-F_Fe-S PF08802.10 KEY67340.1 - 0.068 13.2 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit TFR_dimer PF04253.15 KEY67341.1 - 2.6e-32 111.5 1.1 3e-32 111.3 0.2 1.6 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEY67341.1 - 6e-16 58.7 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY67341.1 - 4.5e-12 45.8 0.1 1e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 PA domain Vps35 PF03635.17 KEY67342.1 - 0 1020.8 0.3 0 1020.6 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pex14_N PF04695.13 KEY67342.1 - 1.8 9.2 9.0 8 7.1 2.0 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim44 PF04280.15 KEY67343.1 - 9.7e-35 119.8 0.2 6.2e-34 117.2 0.0 2.3 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S11 PF00411.19 KEY67344.1 - 6.1e-09 36.3 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 CDC48_N PF02359.18 KEY67344.1 - 0.14 12.3 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain DUF587 PF04532.12 KEY67344.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF587) Peptidase_C97 PF05903.14 KEY67345.1 - 1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KEY67345.1 - 0.02 15.2 0.1 0.03 14.6 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.13 KEY67346.1 - 8.1e-34 115.7 0.1 2.3e-33 114.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KEY67346.1 - 7.7e-16 58.2 0.0 2.8e-15 56.4 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY67346.1 - 0.00028 20.5 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KEY67346.1 - 0.0027 17.7 0.1 0.0064 16.5 0.1 1.6 1 0 0 1 1 1 1 TGS domain PPAK PF02818.15 KEY67346.1 - 0.013 15.6 1.1 0.039 14.1 1.1 1.8 1 0 0 1 1 1 0 PPAK motif AAA_18 PF13238.6 KEY67346.1 - 0.076 13.6 0.5 7.8 7.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain AKAP95 PF04988.12 KEY67346.1 - 0.11 12.8 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) BetaGal_dom3 PF13363.6 KEY67346.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_23 PF13476.6 KEY67346.1 - 2.7 8.4 7.4 1.3e+02 3.0 7.4 2.5 1 1 0 1 1 1 0 AAA domain VPS9 PF02204.18 KEY67348.1 - 1.3e-19 70.3 0.0 3.2e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KEY67348.1 - 7.3e-19 67.6 0.4 9.6e-14 51.3 0.1 4.2 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY67348.1 - 1.4e-15 57.7 0.1 4.3e-06 27.2 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY67348.1 - 3.8e-11 43.3 0.0 0.027 15.0 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY67348.1 - 1.6e-09 37.2 0.1 0.099 13.3 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KEY67348.1 - 7.2e-06 26.2 0.0 3.3 8.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat PX PF00787.24 KEY67348.1 - 0.032 14.2 2.5 0.042 13.8 0.0 2.4 2 1 0 2 2 2 0 PX domain p450 PF00067.22 KEY67349.1 - 1.4e-67 228.5 0.0 1.7e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.19 KEY67350.1 - 2.9e-05 24.4 0.1 9.3e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Fungal_trans_2 PF11951.8 KEY67351.1 - 0.036 12.9 0.0 0.069 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 KEY67352.1 - 5.4e-33 114.5 0.0 6.3e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY67352.1 - 9.6e-11 42.1 0.0 2.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY67352.1 - 2.8e-10 39.9 0.0 4.9e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY67352.1 - 2.2e-05 23.8 0.6 0.11 11.6 0.2 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KEY67352.1 - 0.023 14.3 5.5 0.38 10.3 0.4 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase Med5 PF08689.10 KEY67353.1 - 5.5e-88 296.0 0.0 3.2e-87 293.5 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 TRAP_alpha PF03896.16 KEY67354.1 - 8.7e-08 31.7 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4981 PF16353.5 KEY67354.1 - 0.038 14.5 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) SNF2_N PF00176.23 KEY67355.1 - 4.2e-60 203.3 0.1 7.8e-60 202.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KEY67355.1 - 1.6e-08 34.8 11.6 3e-08 33.8 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEY67355.1 - 4.1e-08 32.9 9.3 8.3e-08 32.0 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY67355.1 - 5.4e-08 32.5 12.5 1.2e-07 31.4 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY67355.1 - 3.1e-06 27.0 11.4 6.4e-06 25.9 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY67355.1 - 2.3e-05 24.1 10.0 4.5e-05 23.2 10.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 KEY67355.1 - 2.5e-05 24.6 0.0 6.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KEY67355.1 - 3.5e-05 23.7 6.8 3.6e-05 23.7 5.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEY67355.1 - 0.00017 21.8 9.6 0.00017 21.8 9.6 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEY67355.1 - 0.0006 19.7 11.3 0.0011 18.8 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 KEY67355.1 - 0.024 14.6 1.2 0.041 13.8 0.4 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 KEY67355.1 - 0.052 13.7 10.4 0.1 12.8 10.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KEY67355.1 - 0.16 11.8 4.4 0.4 10.5 4.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KEY67355.1 - 0.46 10.6 6.4 1.1 9.3 6.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KEY67355.1 - 1 9.3 2.9 2.8 7.9 2.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KEY67355.1 - 2.1 8.1 7.9 11 5.8 7.9 2.2 1 1 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.8 KEY67355.1 - 3.7 7.5 7.5 7.4 6.5 7.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IGR PF09597.10 KEY67356.1 - 2e-25 88.6 0.1 3.2e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif bZIP_2 PF07716.15 KEY67357.1 - 0.00066 19.7 11.2 0.0011 19.0 11.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KEY67357.1 - 0.016 15.3 8.1 0.027 14.6 8.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 KEY67357.1 - 0.54 10.8 8.0 0.99 10.0 8.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.14 KEY67357.1 - 6 5.0 12.3 7.4 4.7 12.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KEY67357.1 - 9.5 4.9 5.6 9.5 4.9 5.6 1.1 1 0 0 1 1 1 0 Presenilin SMAP PF15477.6 KEY67358.1 - 7.5e-09 36.4 7.0 7.5e-09 36.4 7.0 5.9 2 1 0 2 2 2 1 Small acidic protein family RAMP4 PF06624.12 KEY67359.1 - 1.3e-19 70.0 0.4 1.5e-19 69.8 0.4 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4199 PF13858.6 KEY67359.1 - 0.042 14.2 0.0 0.046 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ABC_tran_CTD PF16326.5 KEY67360.1 - 0.033 14.4 0.2 0.054 13.7 0.2 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Cation_ATPase_N PF00690.26 KEY67360.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Mid1 PF12929.7 KEY67361.1 - 2.3e-151 504.8 1.1 2.7e-151 504.6 1.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KEY67361.1 - 0.0018 18.9 8.8 0.05 14.2 1.9 2.8 1 1 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 KEY67362.1 - 1.4e-26 92.2 9.2 2.3e-26 91.5 9.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 2-Hacid_dh_C PF02826.19 KEY67363.1 - 1.8e-51 174.0 0.0 2.8e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY67363.1 - 3.1e-36 124.0 0.0 4.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEY67363.1 - 0.00011 22.3 0.2 0.00038 20.6 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KEY67363.1 - 0.0017 18.0 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 KEY67363.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 ACT domain AdoHcyase_NAD PF00670.21 KEY67363.1 - 0.024 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KEY67363.1 - 0.029 14.9 0.1 0.088 13.3 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain RFX_DNA_binding PF02257.15 KEY67364.1 - 1.5e-24 86.4 0.2 4.6e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain AA_kinase PF00696.28 KEY67365.1 - 9.8e-40 136.7 0.1 1.5e-39 136.0 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KEY67365.1 - 1.9e-09 37.1 0.2 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KEY67365.1 - 1.7e-05 24.5 2.7 0.026 14.3 0.1 2.9 3 0 0 3 3 3 2 ACT domain Sec10 PF07393.11 KEY67366.1 - 8.8e-157 523.6 0.0 1.2e-156 523.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KEY67366.1 - 7e-07 29.1 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY67366.1 - 8.2e-06 25.6 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KEY67366.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 KEY67367.1 - 5e-63 212.9 0.0 5.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67367.1 - 5.1e-33 114.4 0.0 6.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY67367.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KEY67367.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Frag1 PF10277.9 KEY67369.1 - 4.2e-41 140.9 8.1 4.8e-41 140.7 8.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3995 PF13160.6 KEY67369.1 - 0.00089 19.6 4.8 0.043 14.2 1.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3995) DUF4064 PF13273.6 KEY67369.1 - 0.12 12.7 6.9 13 6.1 7.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) MFS_Mycoplasma PF07672.13 KEY67369.1 - 1.7 7.9 12.1 0.38 10.0 5.4 2.1 1 1 1 2 2 2 0 Mycoplasma MFS transporter DUF3278 PF11683.8 KEY67369.1 - 8 6.6 8.2 3.4 7.8 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) Eisosome1 PF12757.7 KEY67370.1 - 8.4e-45 152.1 15.8 8.4e-45 152.1 15.8 4.5 3 2 0 3 3 3 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 KEY67371.1 - 4.8e-46 157.6 0.1 7e-46 157.1 0.1 1.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 KEY67371.1 - 0.0024 16.8 0.1 0.0054 15.7 0.1 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 KEY67371.1 - 0.0026 17.3 0.0 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEY67371.1 - 0.0087 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KEY67371.1 - 0.049 13.5 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_12 PF08242.12 KEY67372.1 - 7.3e-14 52.3 0.0 1.8e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY67372.1 - 1.4e-13 51.3 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY67372.1 - 1.1e-11 44.8 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY67372.1 - 2e-11 44.4 0.0 3.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY67372.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KEY67372.1 - 6.3e-05 24.0 0.0 0.00017 22.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY67372.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KEY67372.1 - 0.00058 19.1 0.0 0.79 8.9 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KEY67372.1 - 0.0029 17.5 0.0 0.0085 16.0 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KEY67372.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.8 KEY67372.1 - 0.064 12.4 0.0 0.19 10.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3419) Ras PF00071.22 KEY67372.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Ras family Roc PF08477.13 KEY67372.1 - 0.19 11.9 0.5 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TPR_11 PF13414.6 KEY67373.1 - 6e-11 41.8 0.0 0.0004 20.0 0.0 3.9 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 KEY67373.1 - 3.4e-10 39.9 2.6 0.00044 20.8 0.1 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY67373.1 - 3.1e-07 30.0 5.3 0.001 19.0 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY67373.1 - 7.4e-07 28.9 0.0 0.0085 16.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY67373.1 - 4.5e-05 23.9 4.2 0.0012 19.3 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEY67373.1 - 6.5e-05 23.0 0.1 0.0025 18.1 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY67373.1 - 6.8e-05 23.4 0.3 0.0015 19.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY67373.1 - 7.1e-05 22.9 0.2 0.00054 20.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF627 PF04781.12 KEY67373.1 - 0.00014 21.8 0.1 0.0013 18.8 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF627) TPR_1 PF00515.28 KEY67373.1 - 0.0003 20.5 0.0 0.015 15.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEY67373.1 - 0.00066 20.0 0.8 0.011 16.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67373.1 - 0.0029 18.1 0.2 11 6.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KEY67373.1 - 0.025 14.6 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_7 PF13176.6 KEY67373.1 - 0.028 14.5 0.3 0.87 9.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEY67373.1 - 0.081 12.8 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 KEY67373.1 - 0.1 12.9 9.1 0.56 10.5 0.4 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat Caldesmon PF02029.15 KEY67375.1 - 1.8e-06 27.0 11.9 1.8e-06 27.0 11.9 2.1 1 1 1 2 2 2 1 Caldesmon Polyketide_cyc PF03364.20 KEY67376.1 - 1.1e-23 83.8 0.0 1.5e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adaptin_N PF01602.20 KEY67377.1 - 2.1e-77 260.9 0.0 4.1e-77 259.9 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEY67377.1 - 0.0064 16.5 0.0 0.098 12.7 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RhoGAP PF00620.27 KEY67378.1 - 1.6e-14 54.0 0.0 5.4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KEY67378.1 - 2.6e-12 46.6 0.0 6.7e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KEY67378.1 - 2.8e-09 37.1 0.0 8.8e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Peptidase_M19 PF01244.21 KEY67379.1 - 3.6e-103 345.1 0.0 4.3e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ribosomal_S13 PF00416.22 KEY67380.1 - 1.9e-15 57.4 0.4 3.2e-13 50.2 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 KEY67381.1 - 6.3e-49 166.3 0.2 8.1e-49 165.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.16 KEY67382.1 - 2.5e-16 60.0 0.1 3.1e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein ATP-synt_S1 PF05827.12 KEY67383.1 - 6.1e-06 26.1 0.5 1.2e-05 25.1 0.5 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 KEY67384.1 - 1.9e-40 138.5 14.0 1.9e-40 138.5 14.0 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) PGA_cap PF09587.10 KEY67384.1 - 3.8 6.9 8.4 2.1 7.8 0.7 2.1 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap EIIBC-GUT_N PF03612.14 KEY67384.1 - 8.5 6.1 15.0 2.3 7.9 5.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Tropomyosin_1 PF12718.7 KEY67385.1 - 3.9e-55 185.9 31.8 5.1e-55 185.6 31.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KEY67385.1 - 1.2e-07 31.4 31.8 0.00023 20.6 18.8 2.9 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 KEY67385.1 - 0.00014 21.9 6.7 0.00014 21.9 6.7 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KEY67385.1 - 0.00099 18.1 33.4 0.0072 15.2 14.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 KEY67385.1 - 0.0015 18.8 33.6 0.68 10.1 17.5 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.6 KEY67385.1 - 0.0018 17.6 31.8 0.037 13.4 18.7 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding SOGA PF11365.8 KEY67385.1 - 0.002 19.2 24.5 0.49 11.6 1.0 3.3 2 1 1 3 3 3 2 Protein SOGA Laminin_II PF06009.12 KEY67385.1 - 0.0026 17.8 4.9 0.0026 17.8 4.9 2.2 1 1 1 2 2 2 1 Laminin Domain II KLRAQ PF10205.9 KEY67385.1 - 0.0046 17.2 22.8 0.024 14.9 6.2 3.2 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein Uso1_p115_C PF04871.13 KEY67385.1 - 0.0063 16.9 34.1 0.42 11.0 15.2 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KEY67385.1 - 0.0068 16.8 20.6 0.13 12.7 2.6 4.5 2 2 2 4 4 4 2 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KEY67385.1 - 0.0081 16.2 29.0 0.096 12.8 5.8 4.2 2 2 2 4 4 4 2 Centrosome localisation domain of PPC89 ADIP PF11559.8 KEY67385.1 - 0.0083 16.2 7.7 0.0083 16.2 7.7 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.11 KEY67385.1 - 0.0093 15.8 2.1 0.053 13.4 0.0 3.0 4 0 0 4 4 2 1 Lung surfactant protein D coiled-coil trimerisation Fez1 PF06818.15 KEY67385.1 - 0.01 16.3 27.6 0.023 15.1 27.5 1.5 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 KEY67385.1 - 0.014 14.7 27.7 0.75 9.1 12.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rab5-bind PF09311.11 KEY67385.1 - 0.015 14.7 23.6 0.099 12.0 11.1 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF2353 PF09789.9 KEY67385.1 - 0.015 14.6 22.9 0.019 14.4 22.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HMMR_N PF15905.5 KEY67385.1 - 0.016 14.7 29.4 0.021 14.3 29.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Taxilin PF09728.9 KEY67385.1 - 0.02 14.1 32.0 0.27 10.4 9.6 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein ZapB PF06005.12 KEY67385.1 - 0.021 15.3 41.7 0.063 13.7 3.0 4.3 1 1 2 3 3 3 0 Cell division protein ZapB MAD PF05557.13 KEY67385.1 - 0.021 13.2 25.2 0.038 12.4 10.1 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4200 PF13863.6 KEY67385.1 - 0.022 15.2 33.5 0.032 14.6 15.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CEP63 PF17045.5 KEY67385.1 - 0.023 14.6 24.7 0.028 14.3 24.7 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF724 PF05266.14 KEY67385.1 - 0.025 14.4 24.0 0.042 13.7 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Alanine_zipper PF11839.8 KEY67385.1 - 0.034 14.5 6.9 2.2 8.7 0.3 3.5 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein XhlA PF10779.9 KEY67385.1 - 0.036 14.3 25.6 0.51 10.6 1.0 4.1 1 1 4 5 5 5 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 KEY67385.1 - 0.044 13.8 36.2 0.16 12.1 9.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KEY67385.1 - 0.047 14.2 39.7 0.19 12.3 24.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region SHE3 PF17078.5 KEY67385.1 - 0.048 13.4 2.1 0.048 13.4 2.1 2.4 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 KEY67385.1 - 0.051 13.8 0.6 0.051 13.8 0.6 4.8 4 1 2 6 6 5 0 Homeobox associated leucine zipper TACC_C PF05010.14 KEY67385.1 - 0.052 13.3 25.4 0.028 14.2 12.9 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ERM PF00769.19 KEY67385.1 - 0.09 12.6 38.3 0.067 13.0 19.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CLZ PF16526.5 KEY67385.1 - 0.1 13.0 27.4 0.26 11.7 3.1 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CALCOCO1 PF07888.11 KEY67385.1 - 0.11 11.4 31.0 0.32 9.8 7.9 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Lebercilin PF15619.6 KEY67385.1 - 0.12 12.0 33.6 0.86 9.2 18.4 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 KEY67385.1 - 0.14 12.4 33.3 0.083 13.1 22.1 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 KEY67385.1 - 0.15 10.9 27.5 0.24 10.2 27.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 KEY67385.1 - 0.16 12.0 14.5 0.29 11.2 3.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 KEY67385.1 - 0.17 11.7 27.9 2 8.2 3.1 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 EzrA PF06160.12 KEY67385.1 - 0.18 10.0 24.0 0.15 10.2 7.4 2.2 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA BRE1 PF08647.11 KEY67385.1 - 0.18 11.9 31.5 1.9 8.6 9.4 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2203 PF09969.9 KEY67385.1 - 0.2 12.4 18.9 1.5 9.6 6.1 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TANGO2 PF05742.12 KEY67385.1 - 0.21 11.6 5.6 0.29 11.1 5.6 1.4 1 1 0 1 1 1 0 Transport and Golgi organisation 2 bZIP_1 PF00170.21 KEY67385.1 - 0.22 11.6 31.8 0.92 9.6 1.5 5.1 2 2 3 5 5 5 0 bZIP transcription factor KASH_CCD PF14662.6 KEY67385.1 - 0.23 11.2 31.6 0.56 10.0 28.0 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CHDCT2 PF08074.11 KEY67385.1 - 0.24 11.6 9.6 0.052 13.7 5.0 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain HAUS-augmin3 PF14932.6 KEY67385.1 - 0.29 10.7 30.5 0.24 10.9 15.8 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 KEY67385.1 - 0.35 11.2 22.4 0.97 9.8 1.6 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 KEY67385.1 - 0.41 11.2 18.3 2.8 8.6 7.2 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cortex-I_coil PF09304.10 KEY67385.1 - 0.53 10.5 22.6 6.9 6.9 5.1 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF5082 PF16888.5 KEY67385.1 - 0.54 10.5 20.9 1.5 9.1 9.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KEY67385.1 - 0.56 10.1 31.0 0.2 11.6 4.2 4.0 1 1 3 4 4 4 0 Prefoldin subunit HMMR_C PF15908.5 KEY67385.1 - 0.59 10.4 18.5 0.068 13.4 4.8 2.8 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Fmp27_WPPW PF10359.9 KEY67385.1 - 0.6 8.9 24.6 0.13 11.1 10.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 KEY67385.1 - 0.62 10.6 7.8 4.3 7.9 0.2 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TFR_dimer PF04253.15 KEY67385.1 - 0.64 10.1 14.0 0.11 12.6 1.3 3.1 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain Seryl_tRNA_N PF02403.22 KEY67385.1 - 0.73 10.1 26.4 4.7 7.5 3.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KEY67385.1 - 0.77 9.9 16.8 2.7 8.2 3.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 KEY67385.1 - 0.84 7.7 29.2 1.8 6.7 29.2 1.4 1 1 0 1 1 1 0 HOOK protein DUF3287 PF11690.8 KEY67385.1 - 1.3 8.8 6.5 6.6 6.5 0.4 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) UPF0242 PF06785.11 KEY67385.1 - 1.3 9.1 32.5 3.3 7.8 10.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus T3SSipB PF16535.5 KEY67385.1 - 1.3 9.4 20.0 9.7 6.6 5.8 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB KELK PF15796.5 KEY67385.1 - 1.5 9.4 32.7 0.22 12.0 5.7 3.8 1 1 3 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FapA PF03961.13 KEY67385.1 - 1.6 7.3 26.1 0.11 11.1 9.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CASP_C PF08172.12 KEY67385.1 - 1.6 8.0 21.3 0.51 9.6 1.0 2.2 1 1 1 2 2 2 0 CASP C terminal AAA_13 PF13166.6 KEY67385.1 - 1.9 7.0 25.7 1.6 7.3 8.4 2.0 1 1 1 2 2 2 0 AAA domain Lectin_N PF03954.14 KEY67385.1 - 2 8.2 16.3 0.47 10.2 6.6 2.7 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain PI3K_P85_iSH2 PF16454.5 KEY67385.1 - 2.1 8.0 26.5 1.1 8.8 19.7 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-Q PF13094.6 KEY67385.1 - 2.1 8.5 34.5 0.78 9.9 5.9 3.3 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.8 KEY67385.1 - 2.4 8.4 31.0 3 8.1 15.5 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding LPP PF04728.13 KEY67385.1 - 2.6 8.5 8.3 12 6.4 0.1 4.0 3 1 1 4 4 3 0 Lipoprotein leucine-zipper Ax_dynein_light PF10211.9 KEY67385.1 - 2.9 7.8 32.8 25 4.7 11.5 3.6 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4472 PF14739.6 KEY67385.1 - 3.1 8.6 27.6 6 7.7 4.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Dynamitin PF04912.14 KEY67385.1 - 3.2 7.0 27.0 2.4 7.4 2.6 2.6 1 1 2 3 3 3 0 Dynamitin Atg14 PF10186.9 KEY67385.1 - 3.3 6.7 22.0 1.7 7.7 10.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec34 PF04136.15 KEY67385.1 - 3.5 7.5 17.5 1 9.2 5.4 2.3 1 1 0 2 2 2 0 Sec34-like family JAKMIP_CC3 PF16034.5 KEY67385.1 - 4.3 7.2 27.9 0.32 10.9 4.8 2.8 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF4686 PF15742.5 KEY67385.1 - 4.3 6.4 34.1 23 4.0 17.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) YabA PF06156.13 KEY67385.1 - 4.5 8.0 25.4 9.2 7.0 1.7 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF5595 PF18077.1 KEY67385.1 - 4.8 7.3 23.5 0.79 9.8 4.0 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF5595) Prefoldin_2 PF01920.20 KEY67385.1 - 5.7 7.0 35.0 0.51 10.3 3.8 4.1 2 1 2 4 4 4 0 Prefoldin subunit BST2 PF16716.5 KEY67385.1 - 6 7.5 30.9 5.4 7.7 10.6 3.7 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 CtIP_N PF10482.9 KEY67385.1 - 6.4 6.8 25.4 1.3 9.1 5.1 2.7 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain OmpH PF03938.14 KEY67385.1 - 6.9 7.0 36.2 4.3 7.7 7.5 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KEY67385.1 - 7.3 7.3 25.0 1.7 9.4 2.4 3.8 1 1 3 4 4 4 0 SlyX TolA_bind_tri PF16331.5 KEY67385.1 - 7.6 6.7 23.0 0.47 10.6 1.0 3.6 2 1 1 3 3 3 0 TolA binding protein trimerisation MPS2 PF17060.5 KEY67385.1 - 8 5.6 14.7 16 4.7 14.1 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 Rootletin PF15035.6 KEY67385.1 - 8.5 6.3 30.0 0.79 9.7 7.2 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3584 PF12128.8 KEY67385.1 - 8.6 3.7 27.3 15 3.0 27.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3811 PF11656.8 KEY67386.1 - 0.025 14.9 0.6 0.09 13.2 0.1 2.1 2 0 0 2 2 2 0 YjbD family (DUF3811) N-SET PF11764.8 KEY67387.1 - 7.9e-52 175.8 0.3 7.9e-52 175.8 0.3 3.7 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KEY67387.1 - 1.2e-26 92.1 0.5 2.9e-26 90.9 0.5 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KEY67387.1 - 1.2e-19 71.3 0.1 1.2e-19 71.3 0.1 4.7 3 3 1 5 5 5 1 SET domain K_channel_TID PF07941.11 KEY67387.1 - 5.2 7.6 8.0 2.6 8.6 0.4 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zn_clus PF00172.18 KEY67390.1 - 1.6e-08 34.5 7.8 2.4e-08 34.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3669 PF12417.8 KEY67391.1 - 5.7e-07 29.6 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Zinc finger protein CLIP_SPH_Scar PF18399.1 KEY67391.1 - 0.11 12.7 0.4 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface F-box PF00646.33 KEY67392.1 - 0.19 11.7 1.8 1 9.3 1.8 2.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KEY67392.1 - 0.88 9.5 5.3 0.13 12.1 0.7 2.0 2 0 0 2 2 2 0 F-box-like GAT PF03127.14 KEY67394.1 - 9.4e-18 64.3 0.5 9.4e-18 64.3 0.5 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 KEY67394.1 - 0.00022 21.1 0.1 0.00071 19.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain DUF3110 PF11360.8 KEY67394.1 - 0.039 14.2 0.0 1.7 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3110) MapZ_EC1 PF18041.1 KEY67394.1 - 0.083 13.1 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 MapZ extracellular domain 1 JmjC PF02373.22 KEY67395.1 - 0.097 13.1 0.3 0.39 11.1 0.1 1.9 1 1 1 2 2 2 0 JmjC domain, hydroxylase Glyco_hydro_3 PF00933.21 KEY67396.1 - 1e-08 34.9 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY67396.1 - 2.6e-08 34.0 0.1 2.2e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain HA2 PF04408.23 KEY67398.1 - 2.2e-22 79.4 0.1 2.2e-22 79.4 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY67398.1 - 2e-21 76.2 0.0 4.1e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 KEY67398.1 - 2.9e-14 53.2 1.4 6e-14 52.1 1.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 KEY67398.1 - 1.3e-13 51.2 0.0 3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KEY67398.1 - 0.00011 21.3 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 KEY67398.1 - 0.00016 21.5 0.8 0.00053 19.8 0.8 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY67398.1 - 0.00017 21.8 0.1 0.00056 20.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY67398.1 - 0.0022 18.3 0.2 0.0069 16.7 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY67398.1 - 0.0027 17.4 0.3 0.012 15.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KEY67398.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KEY67398.1 - 0.06 13.7 0.3 0.3 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 KEY67398.1 - 0.19 12.2 0.7 0.69 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KEY67398.1 - 0.2 11.7 0.1 1.5 8.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain Amidase PF01425.21 KEY67399.1 - 2.6e-81 273.9 0.2 3.3e-81 273.5 0.2 1.1 1 0 0 1 1 1 1 Amidase RNA_GG_bind PF10258.9 KEY67399.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Ribonuclease PF00545.20 KEY67400.1 - 5e-07 30.4 0.0 6.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ribonuclease DIM PF08194.12 KEY67400.1 - 0.032 14.4 0.3 0.032 14.4 0.3 2.4 2 0 0 2 2 2 0 DIM protein UBA_4 PF14555.6 KEY67401.1 - 4e-11 42.5 0.1 1.1e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KEY67401.1 - 7.5e-09 35.7 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.8 KEY67401.1 - 0.0083 16.2 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain DUF1682 PF07946.14 KEY67401.1 - 2.8 7.1 6.3 4.3 6.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pan3_PK PF18101.1 KEY67402.1 - 4.5e-59 198.4 0.0 6.9e-59 197.8 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KEY67402.1 - 2.3e-05 23.9 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.22 KEY67403.1 - 1.5e-19 69.4 0.0 2.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Rhomboid PF01694.22 KEY67405.1 - 1.2e-06 28.6 1.6 2.6e-06 27.5 1.6 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KEY67405.1 - 1.3e-05 25.7 0.9 2.2e-05 24.9 0.7 1.6 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 KEY67405.1 - 0.0082 16.1 3.4 0.012 15.6 3.4 1.3 1 0 0 1 1 1 1 Der1-like family Uds1 PF15456.6 KEY67406.1 - 6.6e-41 139.5 3.8 6.6e-41 139.5 3.8 8.3 4 1 3 7 7 7 1 Up-regulated During Septation Myosin_tail_1 PF01576.19 KEY67406.1 - 4.7e-06 24.7 67.9 4.7e-06 24.7 67.9 5.1 3 1 2 5 5 5 2 Myosin tail Tropomyosin PF00261.20 KEY67406.1 - 0.0017 17.8 50.0 0.0017 17.8 50.0 8.3 5 1 3 8 8 8 3 Tropomyosin HR1 PF02185.16 KEY67406.1 - 0.0043 17.1 0.2 0.0043 17.1 0.2 11.4 9 3 3 12 12 12 2 Hr1 repeat ABC_tran_CTD PF16326.5 KEY67406.1 - 0.0054 17.0 6.7 0.0054 17.0 6.7 12.5 6 2 6 12 12 12 1 ABC transporter C-terminal domain HMG_box PF00505.19 KEY67406.1 - 0.012 16.0 0.2 0.067 13.6 0.2 2.4 1 0 0 1 1 1 0 HMG (high mobility group) box Leu_zip PF15294.6 KEY67406.1 - 0.015 14.8 0.7 0.015 14.8 0.7 7.1 3 1 5 8 8 8 0 Leucine zipper Tcp11 PF05794.13 KEY67407.1 - 1.4e-108 363.8 1.9 2.1e-108 363.3 1.9 1.2 1 0 0 1 1 1 1 T-complex protein 11 TFIID-18kDa PF02269.16 KEY67408.1 - 4.3e-19 68.3 0.4 6.3e-19 67.8 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KEY67408.1 - 0.0029 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KEY67408.1 - 0.0043 17.4 0.9 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 FYDLN_acid PF09538.10 KEY67408.1 - 0.043 14.5 4.4 0.062 14.0 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CBFD_NFYB_HMF PF00808.23 KEY67408.1 - 0.054 13.8 0.5 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KEY67408.1 - 0.055 13.6 0.1 0.075 13.1 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold EamA PF00892.20 KEY67409.1 - 6.5e-19 68.5 28.5 2.6e-11 43.9 6.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1418 PF07214.12 KEY67409.1 - 0.08 12.8 0.2 33 4.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1418) TIP49 PF06068.13 KEY67410.1 - 7e-167 555.0 0.1 9.2e-167 554.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 KEY67410.1 - 2.1e-11 44.4 0.1 1.2e-07 32.3 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TIP49_C PF17856.1 KEY67410.1 - 3e-10 40.1 0.2 9.1e-09 35.3 0.2 2.6 1 1 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KEY67410.1 - 1.2e-09 38.1 0.1 5.5e-07 29.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEY67410.1 - 0.00018 21.8 0.5 0.17 12.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY67410.1 - 0.0005 20.5 0.1 0.0037 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KEY67410.1 - 0.00075 19.8 2.1 0.13 12.6 0.3 2.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KEY67410.1 - 0.0017 18.6 0.1 0.0039 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY67410.1 - 0.0035 17.9 0.0 0.0093 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEY67410.1 - 0.0061 16.2 0.1 0.062 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEY67410.1 - 0.0064 16.5 0.2 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KEY67410.1 - 0.022 14.1 0.2 0.064 12.5 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 KEY67410.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 KEY67410.1 - 0.023 14.4 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KEY67410.1 - 0.027 13.8 0.1 0.68 9.3 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEY67410.1 - 0.028 14.2 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KEY67410.1 - 0.04 13.6 1.0 2.8 7.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KEY67410.1 - 0.043 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KEY67410.1 - 0.11 12.0 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynactin PF12455.8 KEY67411.1 - 1.8e-110 368.7 6.2 1.8e-110 368.7 6.2 3.6 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KEY67411.1 - 3.8e-25 87.7 1.1 6.7e-25 86.9 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain HMG_box PF00505.19 KEY67411.1 - 7.7e-21 74.3 1.5 7.7e-21 74.3 1.5 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEY67411.1 - 7.4e-06 26.5 1.0 5.5e-05 23.7 1.0 2.7 1 0 0 1 1 1 1 HMG-box domain SRP19 PF01922.17 KEY67412.1 - 7.3e-32 110.2 0.0 1.3e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Flg_hook PF02120.16 KEY67413.1 - 0.32 10.9 2.0 3.7 7.5 1.2 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK TelA PF05816.11 KEY67413.1 - 0.37 9.8 5.2 0.56 9.2 5.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) FapA PF03961.13 KEY67413.1 - 0.43 9.1 1.4 0.62 8.6 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCCH PF00642.24 KEY67413.1 - 0.53 10.3 4.6 1.4 9.0 4.6 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.9 KEY67413.1 - 0.94 8.0 5.8 1.3 7.5 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KEY67413.1 - 4.4 6.0 6.0 6.5 5.5 6.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zn_clus PF00172.18 KEY67414.1 - 2.5e-08 33.9 11.3 4.2e-08 33.2 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY67414.1 - 9.9e-07 28.1 0.0 2.3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.21 KEY67415.1 - 7.6e-13 49.0 0.3 7.6e-13 49.0 0.3 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 KEY67416.1 - 1.4e-102 342.1 0.0 2.1e-102 341.5 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PP2C PF00481.21 KEY67417.1 - 8.4e-38 130.5 0.0 5.1e-32 111.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KEY67417.1 - 3.3e-05 23.6 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Crystallin PF00525.18 KEY67417.1 - 0.073 13.2 0.2 0.27 11.4 0.2 2.0 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal EBP50_C PF09007.11 KEY67417.1 - 0.077 14.0 0.3 0.15 13.0 0.3 1.4 1 0 0 1 1 1 0 EBP50, C-terminal Het-C PF07217.11 KEY67418.1 - 1.1e-272 905.7 0.0 1.3e-272 905.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.28 KEY67419.1 - 8.8e-17 61.0 0.2 8.8e-17 61.0 0.2 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KEY67419.1 - 2.7e-13 50.4 16.7 2.7e-13 50.4 16.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KEY67419.1 - 0.031 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KEY67419.1 - 0.048 13.5 2.5 0.11 12.4 0.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 KEY67420.1 - 5.1e-42 141.6 2.2 1e-18 66.9 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KEY67420.1 - 4.3e-22 79.0 0.1 1.3e-21 77.5 0.1 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KEY67420.1 - 0.0064 16.5 0.6 0.26 11.3 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KEY67420.1 - 0.0076 16.1 0.0 0.25 11.2 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KEY67420.1 - 0.024 14.9 0.1 0.25 11.6 0.1 2.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KEY67420.1 - 0.033 14.3 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Flavin_Reduct PF01613.18 KEY67420.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavin reductase like domain DUF885 PF05960.11 KEY67421.1 - 0.011 15.4 0.7 2.2 7.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) VWA PF00092.28 KEY67422.1 - 8.9e-07 29.3 0.0 1.7e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEY67422.1 - 0.0068 17.0 0.0 0.016 15.9 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Aminotran_1_2 PF00155.21 KEY67423.1 - 7.2e-30 104.4 0.0 1e-29 103.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bZIP_2 PF07716.15 KEY67425.1 - 4e-12 46.0 12.1 6.1e-12 45.4 12.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper LCD1 PF09798.9 KEY67425.1 - 0.0011 17.6 0.1 0.0012 17.5 0.1 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein bZIP_1 PF00170.21 KEY67425.1 - 0.0066 16.5 11.9 0.014 15.4 11.9 1.6 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 KEY67425.1 - 0.015 15.5 3.4 0.026 14.7 3.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Shugoshin_N PF07558.11 KEY67425.1 - 0.028 14.3 0.6 0.051 13.4 0.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KEY67425.1 - 0.044 14.1 0.6 0.082 13.2 0.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 KEY67425.1 - 0.047 13.6 2.6 0.094 12.6 2.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KEY67425.1 - 1.3 9.7 5.6 1.2 9.8 3.1 1.9 1 1 1 2 2 2 0 Initiation control protein YabA CENP-N PF05238.13 KEY67426.1 - 1.5e-128 429.6 0.0 1.8e-128 429.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.21 KEY67427.1 - 5.4e-48 163.6 0.0 1e-47 162.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.15 KEY67428.1 - 1.7e-193 644.0 0.0 2.1e-193 643.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KEY67428.1 - 2.7e-24 85.0 0.0 1.1e-23 83.1 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KEY67428.1 - 3.8e-17 62.6 0.0 8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Gal11_ABD1 PF18535.1 KEY67428.1 - 0.16 12.1 0.2 0.4 10.8 0.2 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) CFEM PF05730.11 KEY67429.1 - 7.4e-13 48.4 4.3 1.3e-12 47.7 4.3 1.4 1 0 0 1 1 1 1 CFEM domain ApoLp-III PF07464.11 KEY67429.1 - 0.00034 20.7 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) FlgD_ig PF13860.6 KEY67429.1 - 0.079 12.8 0.5 0.079 12.8 0.5 2.3 3 1 0 3 3 3 0 FlgD Ig-like domain Pirin PF02678.16 KEY67430.1 - 1.4e-30 105.5 0.0 7.2e-29 99.9 0.0 2.3 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KEY67430.1 - 5.7e-27 94.1 0.0 1.2e-25 89.8 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KEY67430.1 - 1.4e-09 37.6 1.2 8.9e-06 25.3 0.3 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KEY67430.1 - 0.00048 19.8 0.2 0.35 10.6 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Perilipin PF03036.16 KEY67431.1 - 0.0052 15.9 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Perilipin family Vault_2 PF17794.1 KEY67431.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Major Vault Protein repeat domain DENN PF02141.21 KEY67432.1 - 1.9e-40 138.8 0.1 3.4e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KEY67432.1 - 1.9e-07 31.7 0.1 1.4e-06 28.9 0.0 2.6 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KEY67432.1 - 0.018 15.5 3.4 0.018 15.5 3.4 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Podovirus_Gp16 PF05894.12 KEY67432.1 - 0.091 12.2 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) TMF_TATA_bd PF12325.8 KEY67432.1 - 6 7.1 17.2 3.1 8.1 7.5 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-HIT PF04438.16 KEY67433.1 - 1.2e-08 34.6 9.9 1.9e-08 34.0 9.9 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KEY67433.1 - 1.5 9.0 8.3 4.5 7.4 8.3 1.9 1 0 0 1 1 1 0 MYND finger Sec6 PF06046.13 KEY67434.1 - 5.7e-166 553.3 8.8 7.9e-166 552.8 8.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KEY67434.1 - 0.00013 21.1 2.1 0.00023 20.2 0.3 2.4 3 0 0 3 3 3 1 Vps53-like, N-terminal FAD_binding_2 PF00890.24 KEY67434.1 - 0.013 14.7 0.1 0.048 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain OmdA PF13376.6 KEY67434.1 - 0.019 15.0 1.8 0.21 11.6 0.0 3.2 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated OEP PF02321.18 KEY67434.1 - 2.8 7.7 7.1 2.3 8.0 0.0 3.3 3 1 0 4 4 4 0 Outer membrane efflux protein EF-hand_4 PF12763.7 KEY67435.1 - 1.1e-35 121.7 0.0 9.9e-14 51.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KEY67435.1 - 5.2e-06 26.2 0.1 1.3e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 KEY67435.1 - 5.8e-05 23.5 0.0 0.051 14.0 0.0 3.5 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KEY67435.1 - 0.00078 19.2 0.0 2 8.5 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain TPR_MLP1_2 PF07926.12 KEY67435.1 - 0.001 19.1 19.2 0.001 19.1 19.2 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KEY67435.1 - 0.002 18.4 24.9 0.32 11.2 2.1 3.3 1 1 2 3 3 3 3 TATA element modulatory factor 1 TATA binding EF-hand_1 PF00036.32 KEY67435.1 - 0.0042 16.5 0.0 2.1 8.1 0.0 3.7 3 0 0 3 3 3 1 EF hand HTH_36 PF13730.6 KEY67435.1 - 0.027 14.4 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-F_leu_zip PF10473.9 KEY67435.1 - 0.097 12.7 26.7 0.12 12.4 14.3 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KEY67435.1 - 0.11 11.8 31.1 0.29 10.4 10.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 KEY67435.1 - 0.13 13.4 16.9 1.8 9.8 6.0 2.8 2 1 0 2 2 2 0 Protein SOGA Macoilin PF09726.9 KEY67435.1 - 0.15 10.6 15.5 0.24 9.9 15.5 1.3 1 0 0 1 1 1 0 Macoilin family FUSC PF04632.12 KEY67435.1 - 0.37 9.3 12.4 0.57 8.7 12.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4201 PF13870.6 KEY67435.1 - 0.41 10.4 29.0 0.26 11.0 12.4 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.21 KEY67435.1 - 0.5 9.9 27.8 2 7.9 9.9 2.3 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 KEY67435.1 - 0.6 8.9 31.8 1.1 8.1 7.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LPP PF04728.13 KEY67435.1 - 0.61 10.5 7.6 3.6 8.0 1.8 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper ATG16 PF08614.11 KEY67435.1 - 1 9.6 38.2 3 8.0 11.6 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KEY67435.1 - 1.2 10.1 29.3 0.09 13.7 9.8 3.7 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 KEY67435.1 - 4.2 7.4 38.1 0.86 9.7 10.9 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KEY67435.1 - 5.4 6.4 30.7 2.2 7.6 24.6 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF2730 PF10805.8 KEY67435.1 - 5.5 7.1 11.8 18 5.5 4.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) APG6_N PF17675.1 KEY67435.1 - 6 7.4 36.0 7.5 7.1 10.0 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region YkyA PF10368.9 KEY67435.1 - 6.1 6.5 25.4 7.5 6.2 12.0 2.4 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Jnk-SapK_ap_N PF09744.9 KEY67435.1 - 6.6 6.9 30.1 6.5 7.0 19.2 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 kleA_kleC PF17383.2 KEY67435.1 - 7.3 7.0 7.6 39 4.7 1.1 3.3 2 2 1 3 3 3 0 Uncharacterized KorC regulated protein A Fez1 PF06818.15 KEY67435.1 - 7.5 6.9 28.3 7.8e+02 0.4 28.4 2.3 1 1 0 1 1 1 0 Fez1 DUF812 PF05667.11 KEY67435.1 - 9.4 5.0 28.5 13 4.5 27.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Pyr_redox_2 PF07992.14 KEY67436.1 - 3.2e-64 217.0 2.3 4.4e-64 216.5 2.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEY67436.1 - 2.3e-33 114.7 0.2 6.5e-33 113.3 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEY67436.1 - 5.4e-22 78.1 1.2 6.8e-20 71.4 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY67436.1 - 4.1e-18 65.7 0.2 5.5e-18 65.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY67436.1 - 2.5e-06 26.9 0.1 6e-05 22.3 0.1 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KEY67436.1 - 8.9e-05 21.4 1.5 0.17 10.5 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KEY67436.1 - 0.0055 16.1 0.2 0.0094 15.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEY67436.1 - 0.0098 15.2 1.8 1.1 8.6 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEY67436.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KEY67436.1 - 0.02 14.0 0.1 0.15 11.2 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Myosin_N PF02736.19 KEY67436.1 - 0.047 13.5 5.7 0.061 13.2 0.3 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Nop16 PF09420.10 KEY67436.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Thi4 PF01946.17 KEY67436.1 - 0.11 11.7 0.3 0.28 10.4 0.3 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KEY67436.1 - 0.17 10.9 2.9 2 7.4 0.6 2.6 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 KEY67436.1 - 0.26 10.8 9.4 0.34 10.4 0.5 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KEY67436.1 - 0.3 10.4 2.2 0.84 9.0 0.1 2.4 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ecl1 PF12855.7 KEY67437.1 - 1.7e-15 58.6 25.9 2e-15 58.4 25.9 1.0 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 KEY67437.1 - 0.042 14.5 1.8 0.042 14.5 1.8 2.1 3 0 0 3 3 3 0 PLATZ transcription factor DUF2116 PF09889.9 KEY67437.1 - 0.055 13.5 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Cpn60_TCP1 PF00118.24 KEY67440.1 - 1.6e-171 571.3 2.7 1.8e-171 571.1 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KEY67440.1 - 0.044 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 KEY67441.1 - 1.5e-35 122.0 10.6 2.1e-35 121.5 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF1682 PF07946.14 KEY67441.1 - 3.4 6.8 9.0 3.8 6.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) His_Phos_1 PF00300.22 KEY67442.1 - 8.1e-26 90.9 0.0 1.6e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 KEY67442.1 - 0.0061 16.7 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 P5-type ATPase cation transporter His_Phos_2 PF00328.22 KEY67442.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) HATPase_c PF02518.26 KEY67443.1 - 5.1e-26 91.4 0.9 1e-25 90.4 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY67443.1 - 5.7e-20 71.5 0.0 1.5e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY67443.1 - 6e-20 71.0 0.0 1.9e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KEY67443.1 - 1.6e-19 70.0 4.8 3.4e-10 40.1 1.0 4.2 4 1 0 4 4 4 3 PAS fold PAS_9 PF13426.7 KEY67443.1 - 6.1e-08 32.9 0.0 0.018 15.3 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KEY67443.1 - 3e-06 27.5 3.0 4.7e-05 23.6 0.2 3.4 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 KEY67443.1 - 3.1e-05 23.9 0.0 0.62 10.1 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KEY67443.1 - 0.0086 16.1 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain Cytochrom_B561 PF03188.16 KEY67444.1 - 3.8e-16 59.5 8.1 7.7e-16 58.5 8.1 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2162 PF09930.9 KEY67444.1 - 0.043 13.2 13.4 0.53 9.7 0.2 2.2 2 0 0 2 2 2 0 Predicted transporter (DUF2162) DUF4006 PF13179.6 KEY67444.1 - 0.31 11.0 4.3 5.2 7.1 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) SLATT_3 PF18184.1 KEY67444.1 - 0.53 10.4 1.8 7.9 6.6 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF3619 PF12279.8 KEY67444.1 - 1.8 8.9 5.5 6.9 7.0 0.2 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3619) DUF4079 PF13301.6 KEY67444.1 - 2.8 8.1 19.0 4.5 7.4 4.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Allantoicase PF03561.15 KEY67445.1 - 4.3e-96 318.6 0.3 4.8e-47 159.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 KEY67446.1 - 1.2e-32 112.2 0.3 2.8e-32 111.1 0.3 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KEY67446.1 - 5e-22 78.3 0.0 4.9e-13 49.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY67446.1 - 3.9e-14 52.8 0.1 6.9e-08 32.9 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY67446.1 - 1.6e-10 40.9 0.0 0.0003 21.1 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEY67446.1 - 2e-08 34.3 0.0 6.9e-06 26.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY67446.1 - 8.7e-07 28.8 0.0 0.28 11.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat RabGAP-TBC PF00566.18 KEY67448.1 - 9e-36 123.5 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CaATP_NAI PF12515.8 KEY67448.1 - 0.61 9.7 4.6 4 7.1 0.1 2.8 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain FA_desaturase PF00487.24 KEY67449.1 - 1.3e-21 77.5 19.1 3.3e-21 76.3 19.1 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KEY67449.1 - 9.9e-07 29.0 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DDE_Tnp_1_7 PF13843.6 KEY67449.1 - 0.00087 18.7 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 KEY67451.1 - 2e-34 119.5 0.0 2.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 p450 PF00067.22 KEY67453.1 - 2.9e-41 141.7 0.0 3.3e-37 128.3 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 eIF-5_eIF-2B PF01873.17 KEY67454.1 - 3.9e-40 136.4 0.0 7.7e-40 135.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KEY67454.1 - 2.5e-23 82.0 0.5 7.6e-23 80.4 0.5 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon efThoc1 PF11957.8 KEY67455.1 - 1.8e-140 468.9 0.2 2.5e-140 468.4 0.2 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KEY67455.1 - 4.1e-24 85.3 0.0 5.2e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 Guanylate kinase Aquarius_N PF16399.5 KEY67456.1 - 0 1100.2 0.0 0 1099.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KEY67456.1 - 1.9e-27 96.2 0.0 3.4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEY67456.1 - 1.6e-20 74.0 0.0 1.5e-19 70.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY67456.1 - 3.1e-07 30.3 0.0 0.00048 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEY67456.1 - 2.1e-06 28.1 0.2 9.6e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KEY67456.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KEY67456.1 - 0.00016 22.1 0.3 0.0062 16.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KEY67456.1 - 0.0034 17.8 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY67456.1 - 0.0037 17.5 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 KEY67456.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.9 KEY67456.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KEY67456.1 - 0.046 14.1 0.0 0.67 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.29 KEY67456.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KEY67456.1 - 0.086 12.6 0.2 4.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEY67456.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 KEY67456.1 - 0.15 11.6 0.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEY67456.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 KEY67456.1 - 0.18 11.3 1.1 0.58 9.6 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KEY67456.1 - 0.2 10.8 0.0 17 4.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Lactamase_B PF00753.27 KEY67457.1 - 0.0042 17.1 0.8 0.0088 16.1 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Mod_r PF07200.13 KEY67458.1 - 6.7e-33 113.8 0.6 7.8e-33 113.6 0.6 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HalX PF08663.10 KEY67458.1 - 0.04 14.2 1.3 0.089 13.1 1.3 1.6 1 0 0 1 1 1 0 HalX domain Spc7 PF08317.11 KEY67458.1 - 0.14 11.0 0.9 0.17 10.7 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein F-box-like PF12937.7 KEY67460.1 - 7.5e-05 22.5 0.3 7.5e-05 22.5 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY67460.1 - 0.00021 21.0 0.2 0.0005 19.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain SUIM_assoc PF16619.5 KEY67460.1 - 0.028 14.5 1.1 0.085 12.9 1.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TolA_bind_tri PF16331.5 KEY67462.1 - 0.29 11.2 1.2 0.67 10.1 0.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation tRNA-synt_2b PF00587.25 KEY67463.1 - 1.7e-31 109.6 0.0 3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Prefoldin PF02996.17 KEY67463.1 - 6.1e-14 52.0 0.0 1.5e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Prefoldin subunit HGTP_anticodon PF03129.20 KEY67463.1 - 4.8e-09 36.2 0.0 9.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DUF2218 PF09981.9 KEY67463.1 - 0.024 15.0 0.1 0.075 13.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) CBF PF03914.17 KEY67464.1 - 1.5e-50 171.6 3.0 6e-50 169.6 0.1 2.6 2 0 0 2 2 2 1 CBF/Mak21 family AAA_23 PF13476.6 KEY67464.1 - 1.6 9.2 12.9 3.8 8.0 12.9 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEY67465.1 - 2.6e-72 241.9 0.0 3.2e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KEY67465.1 - 1.2e-07 31.9 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY67465.1 - 4.5e-06 27.2 0.0 9.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY67465.1 - 0.0008 18.9 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KEY67465.1 - 0.0033 16.7 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.18 KEY67465.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KEY67465.1 - 0.017 15.5 0.1 0.023 15.1 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEY67465.1 - 0.021 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEY67465.1 - 0.03 14.8 0.0 0.055 14.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KEY67465.1 - 0.033 13.9 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 KEY67465.1 - 0.04 12.9 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 RNA_helicase PF00910.22 KEY67465.1 - 0.045 14.1 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KEY67465.1 - 0.082 13.3 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KEY67465.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KEY67465.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Torsin PF06309.11 KEY67465.1 - 0.15 12.2 0.0 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 Torsin G-alpha PF00503.20 KEY67465.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit V-ATPase_C PF03223.15 KEY67466.1 - 1.4e-122 409.7 0.3 1.6e-122 409.5 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APG6_N PF17675.1 KEY67466.1 - 0.17 12.4 3.3 3.8 8.1 0.1 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region AAA PF00004.29 KEY67467.1 - 1.7e-16 60.8 0.0 8.1e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KEY67467.1 - 9.6e-12 44.9 0.2 2.7e-11 43.5 0.1 1.8 2 0 0 2 2 1 1 AAA lid domain AAA_16 PF13191.6 KEY67467.1 - 2.6e-11 44.2 0.1 2.3e-10 41.1 0.0 2.6 3 1 0 3 3 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY67467.1 - 6.7e-10 39.4 0.0 7.8e-09 35.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain BAH PF01426.18 KEY67467.1 - 4.7e-09 36.1 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KEY67467.1 - 0.0006 20.2 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEY67467.1 - 0.0027 17.6 0.0 0.039 13.9 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KEY67467.1 - 0.0034 17.3 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 KEY67467.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KEY67467.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY67467.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY67467.1 - 0.024 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY67467.1 - 0.05 14.0 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_32 PF13654.6 KEY67467.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEY67467.1 - 0.11 11.7 0.0 0.38 9.9 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain UvrD-helicase PF00580.21 KEY67467.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 KEY67467.1 - 0.13 12.2 0.2 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 KEY67467.1 - 0.14 12.2 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KEY67467.1 - 0.24 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.32 KEY67468.1 - 3.6e-44 147.9 19.5 7e-09 36.2 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY67468.1 - 2.3e-05 24.6 1.3 7.8 6.9 0.0 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY67468.1 - 0.096 11.3 2.7 8 5.0 0.0 3.5 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KEY67468.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Ank_2 PF12796.7 KEY67469.1 - 6.1e-50 167.7 4.5 1.9e-15 57.2 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY67469.1 - 5.5e-44 147.7 6.4 1.1e-09 38.4 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY67469.1 - 9.2e-35 118.6 1.8 1.8e-09 38.0 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY67469.1 - 2.2e-32 107.4 0.1 0.0015 18.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KEY67469.1 - 5.9e-30 102.4 2.2 2.3e-05 24.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat TMF_TATA_bd PF12325.8 KEY67470.1 - 2.6e-39 134.0 9.6 2.6e-39 134.0 9.6 7.6 3 1 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KEY67470.1 - 8.2e-16 57.8 9.6 8.2e-16 57.8 9.6 9.4 7 3 2 10 10 10 2 TATA element modulatory factor 1 DNA binding Macoilin PF09726.9 KEY67470.1 - 0.00015 20.5 27.3 0.00015 20.5 27.3 3.4 2 1 1 3 3 3 1 Macoilin family ATG16 PF08614.11 KEY67470.1 - 0.00021 21.6 4.4 0.00021 21.6 4.4 6.3 3 1 3 6 6 6 3 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 KEY67470.1 - 0.013 15.7 17.2 0.013 15.7 17.2 5.6 3 1 2 5 5 5 0 Tropomyosin like DUF948 PF06103.11 KEY67470.1 - 0.18 12.1 24.7 4.8 7.5 0.8 6.5 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KEY67470.1 - 0.43 11.1 21.3 3.3 8.2 0.2 5.5 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Got1 PF04178.12 KEY67471.1 - 1.9e-33 115.3 17.3 2.4e-33 114.9 17.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 KEY67472.1 - 3e-10 39.9 4.6 1.5e-09 37.7 4.6 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain FG-GAP PF01839.23 KEY67472.1 - 0.55 10.4 3.2 1.9 8.7 1.1 2.7 2 0 0 2 2 2 0 FG-GAP repeat NPR3 PF03666.13 KEY67473.1 - 5.2e-139 464.0 0.3 6.5e-139 463.7 0.3 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 EC042_2821 PF18740.1 KEY67473.1 - 0.0097 15.8 1.2 0.019 14.9 1.2 1.4 1 0 0 1 1 1 1 EC042_2821-lke REase FYDLN_acid PF09538.10 KEY67473.1 - 2.7 8.7 10.5 0.38 11.5 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Choline_kinase PF01633.20 KEY67474.1 - 1.3e-50 172.0 0.0 1.1e-49 169.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KEY67474.1 - 2.7e-10 40.6 1.1 5.2e-10 39.7 1.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEY67474.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KEY67474.1 - 0.0016 17.4 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) FAST_1 PF06743.15 KEY67475.1 - 0.23 11.4 0.4 0.59 10.1 0.4 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 zf-C2H2_4 PF13894.6 KEY67475.1 - 0.7 10.9 28.4 0.93 10.5 0.4 6.7 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY67475.1 - 10 6.8 35.3 0.87 10.2 0.8 6.9 7 0 0 7 7 7 0 Zinc finger, C2H2 type Sugar_tr PF00083.24 KEY67476.1 - 3.5e-23 82.2 23.4 4.7e-15 55.4 7.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 KEY67476.1 - 0.0044 17.0 0.4 0.012 15.5 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Pkinase PF00069.25 KEY67477.1 - 1.2e-59 201.8 0.0 2.4e-38 132.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67477.1 - 3.7e-27 95.2 0.0 3.9e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KEY67477.1 - 2.7e-15 56.5 0.0 5.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KEY67477.1 - 3.3e-07 29.9 0.0 0.00023 20.6 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KEY67477.1 - 7.8e-05 22.7 0.0 0.0039 17.1 0.1 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEY67477.1 - 0.0093 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY67477.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEY67477.1 - 0.039 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 bZIP_1 PF00170.21 KEY67478.1 - 7.5e-06 25.9 9.8 1.7e-05 24.8 9.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF5082 PF16888.5 KEY67478.1 - 0.0062 16.8 0.7 0.01 16.1 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) PgdA_N PF18627.1 KEY67478.1 - 0.1 12.3 0.6 0.16 11.6 0.6 1.2 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain bZIP_2 PF07716.15 KEY67478.1 - 2.4 8.3 13.1 28 4.9 13.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper La PF05383.17 KEY67479.1 - 1.2e-19 70.1 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 La domain VP40 PF07447.12 KEY67480.1 - 0.055 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Matrix protein VP40 Pec_lyase_C PF00544.19 KEY67481.1 - 2.7e-41 141.5 0.9 4.2e-41 140.9 0.9 1.2 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 KEY67481.1 - 9.5e-13 47.9 17.3 3.1e-12 46.2 17.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3439 PF11921.8 KEY67481.1 - 0.43 10.5 10.0 1 9.3 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_14 PF13428.6 KEY67483.1 - 7.7e-27 91.7 17.3 2e-05 25.0 0.1 10.0 8 2 2 10 10 10 5 Tetratricopeptide repeat HAT PF02184.16 KEY67483.1 - 5.5e-22 77.4 71.3 6.8e-11 41.9 1.7 13.1 15 0 0 15 15 14 5 HAT (Half-A-TPR) repeat Suf PF05843.14 KEY67483.1 - 4.2e-19 69.7 19.2 3.5e-06 27.2 1.7 6.4 2 1 2 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KEY67483.1 - 4.5e-16 59.1 0.1 1.6e-05 25.3 0.0 7.0 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY67483.1 - 1.1e-07 31.7 3.8 0.36 11.3 0.1 6.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEY67483.1 - 6.7e-07 28.8 14.3 0.1 11.8 1.0 5.5 3 2 0 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67483.1 - 1.1e-06 28.9 17.8 0.037 14.7 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KEY67483.1 - 6e-06 25.6 30.0 0.044 12.9 3.0 6.4 4 3 3 7 7 7 3 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KEY67483.1 - 5.3e-05 23.8 13.4 0.57 10.9 0.0 7.4 8 2 3 11 11 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY67483.1 - 6.8e-05 22.7 14.9 0.59 10.4 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KEY67483.1 - 0.00073 19.6 28.7 0.11 12.6 1.0 7.3 6 1 1 7 7 7 3 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 KEY67483.1 - 0.0035 17.4 1.8 5.5 7.2 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEY67483.1 - 0.011 15.8 10.5 17 5.5 0.3 6.3 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Tnp_22_trimer PF17489.2 KEY67483.1 - 0.035 14.1 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 L1 transposable element trimerization domain TPR_8 PF13181.6 KEY67483.1 - 0.064 13.5 6.1 16 6.0 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY67483.1 - 0.088 12.7 3.8 62 3.7 0.5 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ECSIT PF06239.11 KEY67483.1 - 0.1 11.7 0.1 0.1 11.7 0.1 2.9 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Mad3_BUB1_I PF08311.12 KEY67483.1 - 0.98 9.4 30.2 0.41 10.6 2.3 6.9 6 2 2 8 8 8 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KEY67483.1 - 2.1 8.7 19.5 13 6.2 0.0 7.4 9 1 2 11 11 9 0 Tetratricopeptide repeat Nop PF01798.18 KEY67484.1 - 3.3e-72 242.7 0.0 4.7e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KEY67484.1 - 1.2e-46 158.5 2.1 2.1e-46 157.7 1.2 1.9 2 0 0 2 2 2 1 Prp31 C terminal domain zf-C2H2 PF00096.26 KEY67485.1 - 3.7e-05 23.9 10.0 0.0024 18.2 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type IHO1 PF15771.5 KEY67485.1 - 0.0016 17.3 0.7 0.0025 16.7 0.7 1.2 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 FOXP-CC PF16159.5 KEY67485.1 - 0.0044 17.6 2.3 0.006 17.2 0.3 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KEY67485.1 - 0.0059 17.4 8.0 0.099 13.5 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY67485.1 - 0.014 15.8 1.1 0.014 15.8 1.1 3.3 4 0 0 4 4 4 0 Zinc-finger double domain Integrin_B_tail PF07965.12 KEY67485.1 - 0.027 14.9 0.6 0.054 14.0 0.4 1.6 1 1 0 1 1 1 0 Integrin beta tail domain DUF4864 PF16156.5 KEY67485.1 - 0.046 14.4 0.0 13 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4864) zf-met PF12874.7 KEY67485.1 - 0.077 13.4 6.6 0.37 11.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.17 KEY67486.1 - 9.8e-90 301.1 0.0 1.2e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.24 KEY67488.1 - 1.8e-32 112.8 14.4 4.3e-17 62.1 5.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEY67488.1 - 3.5e-23 82.1 16.3 1.4e-16 60.4 10.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 KEY67489.1 - 3.2e-18 65.9 0.0 6.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY67489.1 - 8.8e-15 54.8 0.0 1.8e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY67489.1 - 9.9e-10 38.6 0.0 2.6e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY67489.1 - 0.00039 20.4 0.1 0.00097 19.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY67489.1 - 0.027 15.0 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY67489.1 - 0.028 14.7 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KEY67489.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin DUF5053 PF16476.5 KEY67489.1 - 0.14 11.8 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) GST_C_3 PF14497.6 KEY67489.1 - 0.15 12.2 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KEY67490.1 - 6.1e-19 68.1 0.1 1.1e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67490.1 - 4.5e-06 26.7 5.2 1.3e-05 25.2 5.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KEY67491.1 - 7.4e-21 74.1 4.5 1.8e-05 25.4 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY67491.1 - 8.9e-12 45.2 0.0 0.16 12.3 0.0 6.8 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY67491.1 - 0.0027 16.4 0.6 0.14 10.8 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KEY67491.1 - 0.026 14.4 0.2 0.66 9.8 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A P2X_receptor PF00864.19 KEY67491.1 - 0.056 12.5 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP P2X receptor Cyclin_N PF00134.23 KEY67492.1 - 1.5e-43 147.6 0.1 2.9e-42 143.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEY67492.1 - 2.5e-35 121.1 0.1 4.5e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 KEY67492.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Ribosomal_L2_C PF03947.18 KEY67493.1 - 1.9e-50 170.3 4.4 4.4e-50 169.1 3.7 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEY67493.1 - 2.9e-23 81.6 0.4 6e-23 80.6 0.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.21 KEY67494.1 - 2.7e-22 79.0 4.8 2.5e-21 75.9 4.8 2.4 1 1 0 1 1 1 1 PAP2 superfamily CK_II_beta PF01214.18 KEY67495.1 - 1.7e-76 256.1 0.2 2.3e-76 255.7 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.13 KEY67496.1 - 4.7e-93 311.2 0.2 6.7e-93 310.7 0.2 1.2 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KEY67496.1 - 0.018 15.0 0.5 11 6.1 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Aminotran_1_2 PF00155.21 KEY67497.1 - 4.8e-16 58.9 0.0 6.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEY67497.1 - 3.9e-07 29.2 0.0 1e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KEY67497.1 - 0.0035 16.7 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.22 KEY67498.1 - 5.8e-64 216.5 0.0 8.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 KEY67499.1 - 1.3e-89 301.1 0.0 1.6e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KEY67499.1 - 3.9e-26 92.3 0.0 6.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KEY67499.1 - 2.3e-06 28.4 0.0 3.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.6 KEY67500.1 - 4.3e-17 61.9 57.3 2.2e-05 24.8 12.5 5.6 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KEY67500.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.24 KEY67501.1 - 1.9e-23 83.5 0.0 3.4e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY67501.1 - 9.1e-12 45.0 0.1 2.7e-11 43.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY67501.1 - 1.1e-07 31.8 0.1 1.1e-05 25.2 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEY67501.1 - 0.0059 15.9 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEY67501.1 - 0.025 13.8 0.0 0.27 10.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEY67501.1 - 0.049 12.5 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 KEY67501.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family Med14 PF08638.11 KEY67502.1 - 2.5e-65 219.5 0.3 4.4e-65 218.7 0.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.16 KEY67503.1 - 3.9e-115 384.0 0.0 7.1e-115 383.2 0.0 1.3 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KEY67503.1 - 4.8e-60 203.2 0.0 8.6e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain ArAE_1_C PF11728.8 KEY67503.1 - 0.04 13.9 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Ribosomal_L35Ae PF01247.18 KEY67504.1 - 4.6e-41 138.9 0.2 5.2e-41 138.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KEY67504.1 - 0.00014 22.0 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 KEY67504.1 - 0.7 9.7 3.3 4.1 7.2 0.2 3.0 2 2 1 3 3 3 0 Putative transposon-encoded protein (DUF2080) DUF2406 PF10295.9 KEY67505.1 - 9.8e-26 90.2 0.0 2.6e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 KEY67506.1 - 1.2e-15 57.4 9.3 1.7e-15 56.9 9.3 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 KEY67507.1 - 1.2e-50 172.2 0.0 1.8e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY67507.1 - 1.6e-15 57.4 0.0 6.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67507.1 - 2.8e-07 30.7 0.0 9.6e-07 29.0 0.0 1.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEY67507.1 - 5.4e-05 22.5 0.2 0.00017 20.9 0.0 1.8 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase VAPB_antitox PF02697.14 KEY67507.1 - 0.13 13.1 0.7 0.44 11.4 0.2 2.3 2 0 0 2 2 2 0 Putative antitoxin Surfac_D-trimer PF09006.11 KEY67507.1 - 0.19 11.6 0.1 7.8 6.5 0.0 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Myb_DNA-bind_6 PF13921.6 KEY67508.1 - 0.071 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sel1 PF08238.12 KEY67510.1 - 2.1e-35 120.4 34.8 1.6e-05 25.4 0.4 7.6 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.15 KEY67511.1 - 8.6e-288 955.2 0.1 1.1e-287 954.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KEY67511.1 - 2.1e-14 53.9 3.4 7.3e-14 52.1 3.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY67511.1 - 7.9e-10 39.0 0.1 3.6e-08 33.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEY67511.1 - 0.00023 20.7 0.0 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEY67511.1 - 0.0013 18.6 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 NepR PF18557.1 KEY67511.1 - 0.082 12.6 0.0 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR Pkinase PF00069.25 KEY67512.1 - 2.4e-67 227.1 0.0 3.5e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67512.1 - 1.1e-40 139.6 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KEY67512.1 - 3.7e-07 30.2 0.0 0.0004 20.5 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KEY67512.1 - 2.6e-05 23.7 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY67512.1 - 0.00032 20.1 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEY67512.1 - 0.0077 15.1 0.1 0.017 13.9 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Sushi_2 PF09014.10 KEY67512.1 - 0.065 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain OPA3 PF07047.12 KEY67513.1 - 1.6e-46 157.1 4.0 1.6e-46 157.1 4.0 2.1 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) DUF3450 PF11932.8 KEY67513.1 - 0.0055 16.1 3.0 0.0055 16.1 3.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF4795 PF16043.5 KEY67513.1 - 0.0085 15.7 0.3 0.0085 15.7 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) FTA4 PF13093.6 KEY67513.1 - 0.012 15.6 1.3 0.015 15.2 1.2 1.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HemX PF04375.14 KEY67513.1 - 0.021 14.2 0.1 0.021 14.2 0.1 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2681 PF10883.8 KEY67513.1 - 0.1 13.0 4.2 0.4 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TMPIT PF07851.13 KEY67513.1 - 0.33 10.2 1.5 0.54 9.5 1.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 KEY67513.1 - 0.61 10.3 4.4 1.7 8.9 4.4 1.8 1 0 0 1 1 1 0 Haemolysin XhlA DnaJ PF00226.31 KEY67513.1 - 2.1 8.6 9.5 1.4 9.1 0.5 3.1 2 2 2 4 4 4 0 DnaJ domain FmiP_Thoc5 PF09766.9 KEY67513.1 - 2.3 7.4 10.0 0.21 10.8 4.9 1.6 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 SBDS PF01172.18 KEY67516.1 - 1.2e-22 79.8 0.0 1.4e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 KEY67517.1 - 6.1e-22 78.7 0.0 1.4e-21 77.6 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.20 KEY67519.1 - 9.7e-51 171.8 1.5 9.7e-51 171.8 1.5 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY67519.1 - 2.8e-46 157.5 4.8 2.8e-46 157.5 4.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY67519.1 - 2.4e-22 80.2 1.1 1.4e-21 77.8 1.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY67519.1 - 1.2e-19 70.1 0.0 2.1e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEY67519.1 - 2.2e-19 68.9 0.1 7.5e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY67519.1 - 2.2e-08 34.2 0.6 4.6e-06 26.6 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY67519.1 - 3.9e-05 24.1 0.0 0.00015 22.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IstB_IS21 PF01695.17 KEY67519.1 - 0.14 11.9 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Proteasome PF00227.26 KEY67520.1 - 2.2e-37 128.4 0.0 2.5e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KEY67521.1 - 5e-25 87.5 0.1 9.9e-25 86.6 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KEY67521.1 - 0.00013 22.0 0.2 0.00034 20.6 0.2 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain DUF4294 PF14127.6 KEY67521.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Voldacs PF03517.13 KEY67521.1 - 0.08 13.1 0.3 0.29 11.2 0.3 1.8 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling UBX PF00789.20 KEY67521.1 - 0.12 12.6 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 UBX domain MSA_2 PF00985.17 KEY67521.1 - 0.39 11.1 5.6 0.65 10.3 5.6 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Herpes_DNAp_acc PF04929.12 KEY67521.1 - 1.3 8.0 5.2 2 7.3 5.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_L36e PF01158.18 KEY67522.1 - 9.2e-41 138.0 6.2 1e-40 137.8 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KEY67522.1 - 0.051 13.6 0.3 0.061 13.4 0.3 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 KEY67522.1 - 0.08 11.7 0.0 0.08 11.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_10 PF12846.7 KEY67522.1 - 0.094 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain MRP-L28 PF09812.9 KEY67522.1 - 0.2 11.8 3.2 0.27 11.4 3.2 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 AltA1 PF16541.5 KEY67523.1 - 0.0011 19.9 2.4 0.0014 19.5 2.4 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Adhesin_P1 PF03257.13 KEY67523.1 - 0.092 13.3 3.8 1.9 9.1 1.0 2.3 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Lipase_3 PF01764.25 KEY67524.1 - 6.7e-32 110.3 0.0 9.2e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY67524.1 - 4.8e-05 24.1 0.0 8.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KEY67524.1 - 0.0035 17.5 0.0 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KEY67524.1 - 0.0088 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KEY67524.1 - 0.011 15.3 0.0 0.077 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.20 KEY67524.1 - 0.064 12.9 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.20 KEY67524.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase PF00151.19 KEY67524.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipase 14-3-3 PF00244.20 KEY67525.1 - 1.1e-106 355.3 1.6 1.3e-106 355.1 1.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 KEY67525.1 - 0.089 13.1 0.2 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 KEY67525.1 - 0.39 11.3 12.1 0.19 12.3 5.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Syja_N PF02383.18 KEY67527.1 - 1.6e-72 244.5 0.0 2.3e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KEY67527.1 - 7.5e-10 38.7 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_14 PF13428.6 KEY67528.1 - 1.1e-06 29.0 3.4 3.7 8.6 0.0 6.9 6 2 2 8 8 8 2 Tetratricopeptide repeat Suf PF05843.14 KEY67528.1 - 0.00016 21.8 7.1 0.027 14.5 0.2 3.3 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) peroxidase PF00141.23 KEY67529.1 - 5.9e-47 160.3 0.0 1e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Amelogenin PF02948.15 KEY67531.1 - 0.033 14.9 0.2 0.039 14.6 0.2 1.1 1 0 0 1 1 1 0 Amelogenin Staph_haemo PF05480.11 KEY67532.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein Thioredoxin PF00085.20 KEY67533.1 - 5.2e-64 212.7 4.4 1.7e-29 101.8 0.1 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KEY67533.1 - 4.2e-45 153.9 3.6 1.8e-35 122.5 0.3 4.2 3 2 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KEY67533.1 - 2.5e-09 37.2 0.0 0.0012 19.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KEY67533.1 - 1e-08 35.1 0.7 0.00054 19.9 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KEY67533.1 - 1.3e-08 35.0 0.0 0.012 15.9 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 KEY67533.1 - 9.9e-08 31.4 1.1 1.8e-07 30.6 0.4 1.7 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 KEY67533.1 - 4.5e-07 30.3 0.5 0.028 14.9 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEY67533.1 - 9.7e-07 28.4 0.5 0.0099 15.3 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 KEY67533.1 - 1.1e-06 28.4 5.6 0.0064 16.2 0.0 3.6 4 0 0 4 4 4 2 Redoxin ERp29_N PF07912.13 KEY67533.1 - 0.00015 21.9 0.2 0.17 12.0 0.0 3.6 4 0 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 KEY67533.1 - 0.019 15.2 5.5 0.29 11.3 0.6 3.6 3 2 1 4 4 4 0 Thioredoxin Ribosomal_60s PF00428.19 KEY67533.1 - 0.1 13.2 13.7 0.084 13.5 10.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein gpW PF02831.15 KEY67534.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 gpW zf-HIT PF04438.16 KEY67535.1 - 1.2e-09 37.9 4.8 1.7e-09 37.3 4.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 KEY67535.1 - 9.9 6.4 7.9 1e+02 3.1 0.1 2.1 1 1 1 2 2 2 0 B-box zinc finger tRNA-synt_2b PF00587.25 KEY67536.1 - 6.8e-34 117.4 0.0 1.6e-32 112.9 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEY67536.1 - 3e-16 59.4 0.2 6e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KEY67536.1 - 1.3e-12 47.6 0.0 2.9e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KEY67536.1 - 2.2e-11 43.6 0.0 5.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain DUF2415 PF10313.9 KEY67537.1 - 0.00044 20.1 0.0 0.00091 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) RNB PF00773.19 KEY67540.1 - 6.1e-52 177.0 0.0 9.1e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF1752 PF08550.10 KEY67541.1 - 2.5e-09 36.8 3.3 5.9e-09 35.6 3.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.16 KEY67543.1 - 2e-71 239.9 0.0 2.6e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein 2OG-FeII_Oxy_2 PF13532.6 KEY67544.1 - 3.5e-29 102.4 0.0 5.4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.19 KEY67545.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 KEY67545.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Sec10 PF07393.11 KEY67546.1 - 5.5e-223 742.4 6.4 6.5e-223 742.2 6.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Hpt PF01627.23 KEY67546.1 - 0.33 11.2 3.8 1 9.7 0.0 3.4 3 0 0 3 3 3 0 Hpt domain FlgN PF05130.12 KEY67546.1 - 0.71 10.4 5.2 0.85 10.1 0.1 3.3 3 0 0 3 3 3 0 FlgN protein Baculo_PEP_C PF04513.12 KEY67546.1 - 0.85 9.7 4.0 2 8.5 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.13 KEY67546.1 - 2.9 8.0 9.2 2.2 8.4 0.7 3.5 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Dus PF01207.17 KEY67547.1 - 9.9e-38 130.0 0.0 3.5e-33 115.0 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) CSD2 PF17876.1 KEY67547.1 - 0.071 13.3 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Cold shock domain IBR PF01485.21 KEY67548.1 - 7.7e-08 32.5 24.7 8.7e-06 25.9 12.9 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain FAA_hydrolase PF01557.18 KEY67549.1 - 3.4e-67 226.3 0.0 4.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KEY67549.1 - 0.026 14.9 0.2 0.045 14.2 0.2 1.3 1 0 0 1 1 1 0 Type II transport protein GspH Complex1_LYR PF05347.15 KEY67550.1 - 9.1e-17 60.9 2.7 1.1e-16 60.7 2.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY67550.1 - 1e-06 29.4 0.2 1.2e-06 29.2 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEY67550.1 - 0.055 14.1 0.9 0.14 12.8 0.9 1.6 1 1 0 1 1 1 0 Complex1_LYR-like ThiS PF02597.20 KEY67552.1 - 2.2e-11 44.2 0.0 3.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family Dynamitin PF04912.14 KEY67553.1 - 1.2e-104 350.7 1.9 1.6e-104 350.3 1.9 1.1 1 0 0 1 1 1 1 Dynamitin FH2 PF02181.23 KEY67553.1 - 0.0056 15.8 0.6 1.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain DUF2408 PF10303.9 KEY67553.1 - 0.018 15.6 2.1 1.2 9.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Fzo_mitofusin PF04799.13 KEY67553.1 - 0.035 13.6 2.7 0.57 9.7 0.4 2.5 2 0 0 2 2 2 0 fzo-like conserved region YkyA PF10368.9 KEY67553.1 - 0.039 13.6 1.3 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein HrpB7 PF09486.10 KEY67553.1 - 0.054 13.9 16.2 0.11 12.9 0.4 4.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) Flagellin_N PF00669.20 KEY67553.1 - 0.081 13.0 6.4 0.1 12.7 0.2 3.1 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region FapA PF03961.13 KEY67553.1 - 0.17 10.5 1.0 3.8 6.0 0.0 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A DHR10 PF18595.1 KEY67553.1 - 0.17 11.9 13.3 3.6 7.7 1.1 3.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 KEY67553.1 - 0.25 11.4 12.2 0.76 9.8 0.5 3.8 3 1 1 4 4 4 0 Laminin Domain II DUF3958 PF13125.6 KEY67553.1 - 0.34 11.1 3.5 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) Matrilin_ccoil PF10393.9 KEY67553.1 - 0.43 10.5 1.6 12 5.9 0.2 2.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Dynactin_p22 PF07426.11 KEY67553.1 - 0.45 10.4 3.4 1.3 8.9 3.4 1.8 1 0 0 1 1 1 0 Dynactin subunit p22 AAA_13 PF13166.6 KEY67553.1 - 0.46 9.1 2.6 0.33 9.6 0.4 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 KEY67553.1 - 0.5 9.7 7.8 1.7 8.0 0.4 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KEY67553.1 - 0.61 10.7 4.1 5.7 7.6 0.2 3.1 3 0 0 3 3 3 0 Initiation control protein YabA SOGA PF11365.8 KEY67553.1 - 0.98 10.6 8.5 0.88 10.7 0.2 3.5 3 1 0 3 3 3 0 Protein SOGA Prefoldin_2 PF01920.20 KEY67553.1 - 0.99 9.4 9.7 0.6 10.1 0.4 3.3 4 0 0 4 4 2 0 Prefoldin subunit BLOC1_2 PF10046.9 KEY67553.1 - 1 9.7 7.7 10 6.5 0.4 3.8 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HWE_HK PF07536.14 KEY67553.1 - 1.2 9.9 6.9 0.45 11.2 0.6 3.4 4 0 0 4 4 4 0 HWE histidine kinase TPR_MLP1_2 PF07926.12 KEY67553.1 - 1.6 8.8 16.5 0.12 12.5 1.9 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.11 KEY67553.1 - 1.8 9.3 6.2 5.5 7.7 0.2 3.2 3 0 0 3 3 3 0 Cytochrome b562 Cluap1 PF10234.9 KEY67553.1 - 1.8 7.9 7.2 3.3 7.0 0.9 3.0 3 0 0 3 3 3 0 Clusterin-associated protein-1 KxDL PF10241.9 KEY67553.1 - 1.9 8.8 4.7 22 5.4 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein FadA PF09403.10 KEY67553.1 - 3 8.4 10.0 5.3 7.6 0.5 3.3 3 0 0 3 3 3 0 Adhesion protein FadA FliD_N PF02465.18 KEY67553.1 - 4.9 7.9 7.8 4.2 8.1 0.8 2.9 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.11 KEY67553.1 - 5.2 7.2 7.9 18 5.5 0.1 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ISG65-75 PF11727.8 KEY67553.1 - 6.6 5.9 7.8 1.6 7.9 0.5 2.7 3 0 0 3 3 3 0 Invariant surface glycoprotein DUF724 PF05266.14 KEY67553.1 - 6.6 6.5 8.8 5.6 6.7 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KEY67553.1 - 7.4 5.4 14.9 0.82 8.5 5.8 3.0 2 2 1 3 3 3 0 Spc7 kinetochore protein XhlA PF10779.9 KEY67553.1 - 8 6.8 11.4 5.2 7.3 0.2 4.1 5 1 0 5 5 3 0 Haemolysin XhlA zf-C4H2 PF10146.9 KEY67553.1 - 8.9 6.6 9.5 45 4.2 0.3 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein RTC4 PF14474.6 KEY67554.1 - 1.4e-29 102.7 0.0 3.2e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain TF_Zn_Ribbon PF08271.12 KEY67554.1 - 0.052 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Alpha-amylase PF00128.24 KEY67555.1 - 2e-115 386.0 0.3 2e-115 386.0 0.3 1.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KEY67555.1 - 7.9e-08 32.3 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain LPD24 PF18839.1 KEY67555.1 - 0.012 15.9 2.9 0.31 11.3 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 DUF3459 PF11941.8 KEY67555.1 - 0.027 14.8 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) 7TM_GPCR_Sru PF10322.9 KEY67556.1 - 0.2 10.9 8.1 0.34 10.2 8.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF3789 PF12664.7 KEY67556.1 - 0.29 10.9 4.2 0.76 9.5 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) adh_short_C2 PF13561.6 KEY67557.1 - 2e-36 125.7 0.8 2.5e-36 125.4 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY67557.1 - 2.5e-28 98.9 0.1 3.7e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY67557.1 - 0.0013 18.6 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KEY67557.1 - 0.015 15.2 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Glycos_transf_2 PF00535.26 KEY67557.1 - 0.059 13.2 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Dak1_2 PF13684.6 KEY67557.1 - 0.065 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Rossmann-like PF10727.9 KEY67557.1 - 0.15 11.9 2.8 0.32 10.9 0.5 2.3 3 0 0 3 3 3 0 Rossmann-like domain adh_short PF00106.25 KEY67558.1 - 3.8e-24 85.2 0.1 3.9e-22 78.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67558.1 - 7.6e-13 48.5 0.3 5.8e-11 42.4 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67558.1 - 4.8e-12 46.1 0.1 7.3e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY67558.1 - 3.1e-07 30.1 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY67558.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Phospholip_A2_3 PF09056.11 KEY67559.1 - 1.8e-28 99.4 0.2 3.3e-28 98.5 0.2 1.4 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 tRNA-synt_2 PF00152.20 KEY67560.1 - 6.5e-83 278.4 0.0 1.3e-82 277.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEY67560.1 - 0.00027 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1441 PF07278.11 KEY67560.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) Cu-oxidase_2 PF07731.14 KEY67562.1 - 7.9e-41 139.0 6.0 6e-39 132.9 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY67562.1 - 6.5e-37 126.2 1.4 6.5e-37 126.2 1.4 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY67562.1 - 4.6e-34 117.8 1.9 4.6e-34 117.8 1.9 2.8 3 1 0 3 3 3 1 Multicopper oxidase Big_11 PF18200.1 KEY67562.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain DUF3433 PF11915.8 KEY67563.1 - 4.4e-14 52.7 1.1 4.4e-14 52.7 1.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF2721 PF11026.8 KEY67564.1 - 5.7 6.8 7.3 0.75 9.7 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SnoaL_4 PF13577.6 KEY67565.1 - 1.1e-09 38.5 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.26 KEY67566.1 - 4.9e-18 66.2 0.6 6.9e-18 65.7 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fungal_trans PF04082.18 KEY67567.1 - 3.4e-20 72.2 0.0 5.6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY67567.1 - 5.2e-08 32.9 12.2 0.0013 19.1 1.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY67567.1 - 4e-07 30.2 12.4 6.1e-07 29.6 6.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY67567.1 - 0.00089 19.9 12.3 0.099 13.5 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY67567.1 - 0.061 13.6 3.1 0.43 10.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KEY67567.1 - 0.35 11.2 2.0 0.81 10.0 2.0 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-met PF12874.7 KEY67567.1 - 2.4 8.6 4.9 0.62 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PBP1_TM PF14812.6 KEY67568.1 - 4.7 7.6 9.0 0.15 12.5 2.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arrestin_C PF02752.22 KEY67569.1 - 9.4e-17 61.7 0.0 7.6e-16 58.8 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KEY67569.1 - 3.3e-05 24.0 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain GTP_EFTU PF00009.27 KEY67570.1 - 1e-18 67.6 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEY67570.1 - 2.2e-09 37.5 0.4 1.2e-08 35.2 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KEY67570.1 - 1.6e-05 25.2 0.0 4.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KEY67570.1 - 0.0021 18.1 0.2 0.0087 16.1 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY67570.1 - 0.049 13.5 0.5 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KEY67570.1 - 0.054 13.6 0.2 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KEY67570.1 - 0.11 12.3 0.2 1.7 8.3 0.1 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation LSM PF01423.22 KEY67571.1 - 2.5e-19 68.7 0.2 2.9e-19 68.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 KEY67572.1 - 4e-17 62.1 0.0 7.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression SesA PF17107.5 KEY67573.1 - 0.0001 22.4 0.1 0.00024 21.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Utp8 PF10395.9 KEY67575.1 - 4.8e-08 32.0 0.0 5.8e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Utp8 family AAA PF00004.29 KEY67576.1 - 1.2e-07 32.3 0.5 1.3e-06 28.8 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEY67576.1 - 4.5e-07 30.0 0.1 0.0043 17.0 0.0 3.3 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 KEY67576.1 - 0.00065 20.1 0.0 0.0022 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY67576.1 - 0.0023 18.2 0.1 0.0093 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEY67576.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 KEY67576.1 - 0.015 15.9 0.0 0.042 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KEY67576.1 - 0.017 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Caskin-tail PF16632.5 KEY67576.1 - 0.053 13.9 0.1 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 C-terminal region of Caskin TsaE PF02367.17 KEY67576.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KEY67576.1 - 0.081 13.4 0.7 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KEY67576.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ANTH PF07651.16 KEY67579.1 - 2.7e-67 226.7 0.1 3.5e-67 226.3 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KEY67579.1 - 8.7e-08 32.3 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.13 KEY67580.1 - 2.8e-32 112.2 2.7 3.6e-32 111.8 2.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KEY67580.1 - 1.1e-30 105.2 9.7 1.8e-30 104.6 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY67580.1 - 0.00027 20.7 6.1 0.00073 19.4 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY67580.1 - 0.00032 20.5 6.9 0.0006 19.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67580.1 - 0.0022 18.3 6.8 0.0043 17.4 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEY67580.1 - 0.013 15.3 7.6 0.045 13.6 7.7 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 KEY67580.1 - 0.018 14.9 8.8 0.027 14.4 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3797 PF12677.7 KEY67580.1 - 0.023 14.6 3.4 0.05 13.5 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_10 PF16685.5 KEY67580.1 - 0.097 12.8 3.0 0.19 11.9 3.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KEY67580.1 - 0.35 10.9 6.5 0.66 10.0 6.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KEY67580.1 - 0.38 10.6 12.2 3.8 7.4 12.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KEY67580.1 - 1.6 8.7 11.2 19 5.3 11.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KEY67580.1 - 7.2 6.6 8.5 49 3.9 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KEY67580.1 - 8.1 6.6 8.5 42 4.4 8.5 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger CS PF04969.16 KEY67581.1 - 9.8e-17 61.7 0.8 1.9e-16 60.8 0.3 1.8 2 0 0 2 2 2 1 CS domain LicD PF04991.13 KEY67583.1 - 2.7e-10 40.8 4.1 3.7e-05 24.0 0.1 3.1 2 1 1 3 3 3 3 LicD family ER_lumen_recept PF00810.18 KEY67584.1 - 1.6e-42 145.8 13.1 2.5e-42 145.2 13.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KEY67584.1 - 0.024 14.4 6.7 0.072 12.9 0.0 2.9 3 0 0 3 3 3 0 PQ loop repeat ADK PF00406.22 KEY67585.1 - 1.7e-35 122.4 0.0 3.5e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KEY67585.1 - 1.3e-15 57.1 0.0 2.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KEY67585.1 - 4.4e-12 46.6 0.0 1.7e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEY67585.1 - 0.005 17.4 0.0 0.05 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEY67585.1 - 0.012 15.8 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1275 PF06912.11 KEY67587.1 - 2.3e-44 151.6 17.1 2.7e-44 151.4 17.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Lactamase_B PF00753.27 KEY67589.1 - 3.3e-18 66.4 0.9 4.7e-18 65.9 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY67589.1 - 0.0084 15.6 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sulf_transp PF04143.14 KEY67590.1 - 1.1e-29 104.0 26.1 1.1e-29 104.0 26.1 2.2 1 1 1 2 2 2 1 Sulphur transport TOM13 PF08219.11 KEY67590.1 - 0.12 12.3 0.1 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Outer membrane protein TOM13 Zn_clus PF00172.18 KEY67591.1 - 7.8e-09 35.5 6.9 7.8e-09 35.5 6.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY67591.1 - 1.3e-06 27.7 0.1 2.5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KEY67592.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Imm10 PF15588.6 KEY67592.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 10 LETM1 PF07766.13 KEY67593.1 - 1.9e-101 338.9 0.7 5.7e-101 337.4 0.7 1.9 1 0 0 1 1 1 1 LETM1-like protein PX PF00787.24 KEY67593.1 - 1.3e-20 73.4 0.4 4.5e-20 71.7 0.4 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KEY67593.1 - 0.0023 17.5 16.8 0.017 14.7 0.3 3.2 3 0 0 3 3 3 2 Vps5 C terminal like SAP PF02037.27 KEY67593.1 - 0.0024 17.6 0.0 0.048 13.4 0.0 2.8 2 0 0 2 2 2 1 SAP domain Peptidase_S8 PF00082.22 KEY67594.1 - 9.3e-37 126.9 2.3 1.4e-36 126.3 2.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KEY67594.1 - 6.7e-28 96.5 0.8 1.3e-27 95.6 0.8 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PepSY_TM PF03929.16 KEY67594.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM region S8_pro-domain PF16470.5 KEY67594.1 - 0.075 13.8 0.1 0.24 12.2 0.1 1.9 1 0 0 1 1 1 0 Peptidase S8 pro-domain Mito_carr PF00153.27 KEY67595.1 - 1.7e-39 133.6 4.1 5.6e-16 58.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KEY67596.1 - 0.002 17.2 0.5 0.005 15.9 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67596.1 - 0.0067 16.5 10.8 0.013 15.6 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KEY67597.1 - 1e-15 58.1 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY67597.1 - 3e-15 56.4 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEY67597.1 - 1.1e-05 25.0 0.0 0.00013 21.6 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY67597.1 - 0.00077 19.4 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY67597.1 - 0.0028 17.9 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KEY67597.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KEY67597.1 - 0.1 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Zip PF02535.22 KEY67598.1 - 8.8e-30 104.0 32.4 7.7e-13 48.4 2.9 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter VWA_N2 PF16164.5 KEY67598.1 - 0.048 13.8 3.7 0.062 13.4 2.1 2.1 1 1 1 2 2 2 0 VWA N-terminal Pectate_lyase PF03211.13 KEY67599.1 - 8.6e-49 165.8 0.8 1e-48 165.6 0.8 1.0 1 0 0 1 1 1 1 Pectate lyase gerPA PF10676.9 KEY67599.1 - 0.092 13.0 1.5 0.22 11.8 0.9 1.8 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF Filament PF00038.21 KEY67600.1 - 0.00094 18.8 6.7 0.0023 17.6 6.7 1.6 1 0 0 1 1 1 1 Intermediate filament protein Yuri_gagarin PF15934.5 KEY67600.1 - 0.017 15.0 5.1 0.032 14.1 5.1 1.4 1 0 0 1 1 1 0 Yuri gagarin GAS PF13851.6 KEY67600.1 - 0.042 13.2 11.5 0.092 12.1 11.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IL34 PF15036.6 KEY67600.1 - 0.042 13.9 1.2 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 Interleukin 34 KxDL PF10241.9 KEY67600.1 - 0.044 14.1 0.5 0.044 14.1 0.5 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Vps5 PF09325.10 KEY67600.1 - 0.053 13.1 10.0 0.015 14.8 5.2 2.4 2 2 1 3 3 3 0 Vps5 C terminal like Laminin_II PF06009.12 KEY67600.1 - 0.13 12.3 7.3 0.065 13.3 4.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Ntox28 PF15605.6 KEY67600.1 - 0.24 11.7 2.6 0.45 10.8 0.4 2.3 1 1 0 2 2 2 0 Bacterial toxin 28 ASL_C PF08328.11 KEY67600.1 - 0.4 10.8 2.6 9.8 6.3 0.4 2.9 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal Cnn_1N PF07989.11 KEY67600.1 - 0.97 9.6 7.3 1.7 8.9 1.6 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 KEY67600.1 - 1.3 7.5 6.6 2.1 6.8 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KEY67600.1 - 1.8 8.6 8.0 9.5 6.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KEY67600.1 - 1.9 8.6 14.7 0.92 9.6 5.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.10 KEY67600.1 - 6.5 7.0 14.7 4.4 7.6 3.6 3.4 2 1 1 3 3 3 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.22 KEY67600.1 - 6.6 7.0 12.9 4.7 7.5 8.4 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.18 KEY67600.1 - 9.1 7.1 10.9 1.8 9.3 2.2 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3678 PF12435.8 KEY67601.1 - 9.6 5.7 7.8 0.54 9.7 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) GH131_N PF18271.1 KEY67604.1 - 6.8e-63 212.7 0.4 8.4e-63 212.4 0.4 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain p450 PF00067.22 KEY67605.1 - 2.1e-51 175.1 0.0 2.7e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HMG-CoA_red PF00368.18 KEY67606.1 - 4.2e-140 466.9 5.2 5.5e-140 466.5 5.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KEY67606.1 - 1.5e-37 128.9 0.0 2.7e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KEY67606.1 - 1.3e-14 54.3 6.2 8.3e-13 48.4 6.2 2.6 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KEY67606.1 - 4.2e-06 25.1 3.3 6.9e-06 24.4 3.3 1.2 1 0 0 1 1 1 1 Patched family SpoIIIAH PF12685.7 KEY67606.1 - 0.0085 16.0 0.3 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein ECSIT_C PF14784.6 KEY67606.1 - 0.022 15.1 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Isochorismatase PF00857.20 KEY67607.1 - 1.1e-27 97.3 0.0 2.9e-27 96.0 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family DUF202 PF02656.15 KEY67608.1 - 1e-20 73.9 0.6 1e-20 73.9 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_11 PF13086.6 KEY67609.1 - 3.1e-59 200.9 0.4 1.3e-58 198.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KEY67609.1 - 2e-54 184.3 0.0 5.4e-54 182.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KEY67609.1 - 1.9e-11 44.1 0.1 3.9e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEY67609.1 - 3.2e-09 37.3 0.0 1.8e-08 34.8 0.0 2.4 3 1 0 3 3 1 1 AAA domain ResIII PF04851.15 KEY67609.1 - 4.3e-07 30.1 0.0 2.1e-05 24.6 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KEY67609.1 - 1.3e-06 28.4 0.0 0.65 9.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KEY67609.1 - 1.5e-06 28.0 0.0 3.3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KEY67609.1 - 6.5e-06 25.6 0.1 5.6e-05 22.6 0.1 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KEY67609.1 - 5.6e-05 23.0 0.1 0.0024 17.6 0.1 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 KEY67609.1 - 0.00022 21.1 0.1 0.014 15.3 0.0 2.8 2 1 0 2 2 2 1 Helicase T2SSE PF00437.20 KEY67609.1 - 0.00031 19.9 0.0 0.00058 19.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KEY67609.1 - 0.0005 20.1 0.0 0.002 18.1 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.6 KEY67609.1 - 0.00063 20.0 0.1 0.0067 16.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY67609.1 - 0.0012 19.3 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KEY67609.1 - 0.0023 17.6 0.2 0.46 10.0 0.0 3.8 2 1 3 5 5 5 1 AAA domain PhoH PF02562.16 KEY67609.1 - 0.0057 16.1 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KEY67609.1 - 0.0072 16.1 0.1 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 KEY67609.1 - 0.0082 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KEY67609.1 - 0.0096 15.7 0.1 0.089 12.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEY67609.1 - 0.011 15.6 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KEY67609.1 - 0.012 16.1 0.0 0.073 13.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY67609.1 - 0.027 14.5 0.2 0.15 12.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KEY67609.1 - 0.06 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KEY67609.1 - 0.068 13.1 0.4 6.2 6.7 0.0 3.0 2 1 1 3 3 3 0 Rad17 P-loop domain UvrD_C PF13361.6 KEY67609.1 - 0.11 11.8 0.4 1.9 7.8 0.0 2.7 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain cobW PF02492.19 KEY67609.1 - 0.15 11.6 0.5 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TK PF00265.18 KEY67609.1 - 0.18 11.7 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase 4HB_MCP_1 PF12729.7 KEY67609.1 - 0.22 11.1 2.2 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Ribosomal_L30_N PF08079.12 KEY67609.1 - 0.6 10.4 4.5 1.6 9.1 4.5 1.7 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain T7SS_ESX_EspC PF10824.8 KEY67610.1 - 0.091 13.2 0.1 0.27 11.7 0.1 1.8 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm MbeD_MobD PF04899.12 KEY67610.1 - 0.37 10.9 1.2 0.68 10.1 0.1 1.9 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_M3 PF01432.20 KEY67611.1 - 1.9e-120 403.2 0.0 2.7e-120 402.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 MCM_lid PF17855.1 KEY67611.1 - 0.0005 20.4 0.2 0.0021 18.4 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Peptidase_M50B PF13398.6 KEY67611.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.9 KEY67612.1 - 2.8e-44 150.2 0.1 1.5e-43 147.8 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.17 KEY67613.1 - 1.8e-45 155.4 0.1 8e-45 153.3 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ATP_bind_2 PF03668.15 KEY67613.1 - 0.15 11.3 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family Oxysterol_BP PF01237.18 KEY67615.1 - 9.1e-88 294.6 0.0 2.5e-85 286.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.24 KEY67616.1 - 1.3e-08 34.6 18.6 5.4e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KEY67616.1 - 0.0042 16.9 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KEY67616.1 - 0.0071 17.0 3.2 0.41 11.4 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KEY67616.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KEY67616.1 - 3.9 7.7 8.2 0.59 10.4 0.9 2.5 1 1 0 2 2 2 0 Zinc-finger containing family ELMO_CED12 PF04727.13 KEY67617.1 - 1e-49 169.0 0.0 2.8e-49 167.6 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KEY67617.1 - 9.9e-42 142.7 0.1 2e-41 141.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KEY67617.1 - 2.3e-14 53.6 0.0 6.4e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ZFYVE21_C PF16696.5 KEY67617.1 - 0.031 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus TetR_C_28 PF17937.1 KEY67617.1 - 0.23 11.9 3.0 7.4 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PRA1 PF03208.19 KEY67618.1 - 2.1e-34 118.2 0.5 3.1e-34 117.6 0.5 1.2 1 0 0 1 1 1 1 PRA1 family protein BRE1 PF08647.11 KEY67618.1 - 0.049 13.7 3.1 0.08 13.0 3.1 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Renin_r PF07850.14 KEY67618.1 - 0.9 10.2 2.2 0.88 10.2 0.1 2.1 2 0 0 2 2 2 0 Renin receptor-like protein PV-1 PF06637.11 KEY67618.1 - 3.2 6.5 7.6 4.4 6.0 7.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PP28 PF10252.9 KEY67618.1 - 8.8 6.9 18.8 4.2 7.9 16.0 1.9 1 1 1 2 2 2 0 Casein kinase substrate phosphoprotein PP28 UQ_con PF00179.26 KEY67619.1 - 6.9e-32 110.0 0.0 8.3e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KEY67619.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KEY67619.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain HRDC PF00570.23 KEY67619.1 - 0.095 12.7 0.7 0.21 11.6 0.7 1.6 1 0 0 1 1 1 0 HRDC domain UFC1 PF08694.11 KEY67619.1 - 0.18 11.5 0.0 0.7 9.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Anp1 PF03452.14 KEY67620.1 - 4.9e-111 370.4 0.0 5.7e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KEY67620.1 - 0.045 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 RRM_1 PF00076.22 KEY67621.1 - 1.6e-19 69.5 0.0 2.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KEY67621.1 - 0.006 17.1 23.8 0.006 17.1 23.8 4.0 3 2 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF1932 PF09130.11 KEY67622.1 - 1.2e-22 79.7 0.7 2.7e-22 78.5 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KEY67622.1 - 2.8e-08 34.3 0.1 8.2e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEY67622.1 - 7.4e-07 29.5 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KEY67622.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEY67622.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KEY67622.1 - 0.0067 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 KEY67622.1 - 0.0096 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase tRNA-synt_1 PF00133.22 KEY67624.1 - 2.3e-221 736.2 0.7 5.2e-220 731.8 0.7 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEY67624.1 - 5.3e-30 104.4 1.0 5.3e-30 104.4 1.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KEY67624.1 - 9.5e-14 51.3 0.0 4.3e-10 39.4 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KEY67624.1 - 3.9e-13 48.9 0.4 1.5e-05 24.0 0.0 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KEY67624.1 - 0.00039 20.6 9.6 0.00039 20.6 9.6 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DUF1743 PF08489.11 KEY67624.1 - 0.081 13.0 0.5 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) tRNA-synt_1e PF01406.19 KEY67624.1 - 0.2 11.0 2.4 1.3 8.3 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Adaptin_binding PF10199.9 KEY67624.1 - 2.1 9.0 8.4 11 6.7 0.9 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DEAD PF00270.29 KEY67625.1 - 2.3e-47 161.0 0.0 4.4e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY67625.1 - 8.6e-28 96.9 0.3 4.8e-27 94.5 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67625.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KEY67625.1 - 0.0039 17.7 3.2 0.0039 17.7 3.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2986) PRAI PF00697.22 KEY67625.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CMS1 PF14617.6 KEY67625.1 - 0.54 9.6 0.0 0.54 9.6 0.0 3.1 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Mitoc_mL59 PF18126.1 KEY67626.1 - 2.2e-43 147.6 2.7 2.6e-43 147.4 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KEY67627.1 - 2.3e-17 62.5 0.9 3.4e-17 61.9 0.9 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KEY67627.1 - 3.4e-11 43.1 0.0 5.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 KEY67628.1 - 3.8e-107 356.8 4.1 4.4e-107 356.6 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm71 PF15602.6 KEY67628.1 - 0.065 13.3 0.1 2.1 8.4 0.0 2.2 1 1 0 2 2 2 0 Immunity protein 71 TPR_19 PF14559.6 KEY67628.1 - 0.43 11.1 4.1 0.75 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IATP PF04568.12 KEY67629.1 - 6.7e-32 109.8 1.5 7.5e-32 109.7 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2205 PF10224.9 KEY67629.1 - 0.18 11.8 3.5 0.25 11.3 3.5 1.2 1 0 0 1 1 1 0 Short coiled-coil protein XhlA PF10779.9 KEY67629.1 - 0.3 11.3 1.8 0.46 10.7 1.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF1003 PF06210.11 KEY67629.1 - 0.33 11.1 2.4 0.46 10.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.13 KEY67630.1 - 3.4e-38 130.0 3.6 3.4e-38 130.0 3.6 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KEY67630.1 - 6.6e-26 91.0 204.4 1.1e-08 35.8 27.3 8.0 2 1 5 8 8 8 7 Nucleoporin FG repeat region NPV_P10 PF05531.12 KEY67630.1 - 1 9.9 2.4 1.8 9.1 0.1 2.4 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KEY67630.1 - 3.1 7.5 7.3 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KEY67630.1 - 3.1 7.8 4.0 48 4.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 KEY67630.1 - 4.6 7.5 8.5 25 5.2 0.6 3.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG V-SNARE PF05008.15 KEY67630.1 - 8.4 6.9 8.6 4.3 7.8 0.9 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF5102 PF17104.5 KEY67631.1 - 3.2e-113 378.6 2.4 3.2e-113 378.6 2.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 KEY67632.1 - 4.7e-34 116.5 0.5 1.1e-33 115.3 0.5 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KEY67632.1 - 2.2e-22 79.5 1.7 3.4e-21 75.7 1.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEY67632.1 - 3.5e-09 36.9 0.3 7.4e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY67632.1 - 0.0036 17.4 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KEY67632.1 - 0.0053 16.8 0.8 0.017 15.1 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KEY67632.1 - 0.026 14.4 0.2 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase MARVEL PF01284.23 KEY67633.1 - 0.00089 19.3 6.8 0.00089 19.3 6.8 1.8 1 1 1 2 2 2 1 Membrane-associating domain Peptidase_M56 PF05569.11 KEY67633.1 - 0.03 13.5 2.7 0.051 12.7 2.7 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ninjurin PF04923.12 KEY67633.1 - 0.11 12.5 1.9 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Ninjurin TctB PF07331.11 KEY67633.1 - 0.97 9.7 3.9 0.19 12.0 0.4 1.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3290 PF11694.8 KEY67633.1 - 1.3 9.0 4.2 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) PhoLip_ATPase_C PF16212.5 KEY67633.1 - 2.3 7.9 9.9 9.6 5.9 10.2 1.7 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF5527 PF17665.1 KEY67633.1 - 2.5 7.6 5.9 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DEAD PF00270.29 KEY67634.1 - 9.8e-46 155.7 0.8 1.6e-45 155.0 0.8 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY67634.1 - 5.1e-32 110.5 0.2 8.8e-31 106.5 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67634.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEY67634.1 - 0.00037 20.3 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY67634.1 - 0.002 18.5 1.4 0.0086 16.4 0.4 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KEY67634.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KEY67634.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KEY67634.1 - 0.088 12.8 0.1 0.35 10.8 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain fragilysinNterm PF16376.5 KEY67634.1 - 0.089 12.5 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of fragilysin AAA_22 PF13401.6 KEY67634.1 - 0.11 12.8 0.4 0.58 10.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 KEY67635.1 - 1.7e-16 60.7 0.0 7.1e-14 52.1 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 KEY67635.1 - 1.3e-10 41.8 0.0 3.4e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KEY67635.1 - 3.4e-07 30.1 2.2 6.9e-07 29.1 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KEY67635.1 - 6.4e-06 25.9 0.4 1.9e-05 24.4 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KEY67635.1 - 0.0015 18.4 0.1 0.043 13.7 0.0 2.3 2 0 0 2 2 2 1 F-box Cupin_4 PF08007.12 KEY67635.1 - 0.047 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein SNARE_assoc PF09335.11 KEY67636.1 - 1.6e-15 57.7 5.9 1.6e-15 57.7 5.9 2.2 1 1 0 2 2 2 1 SNARE associated Golgi protein DUF1771 PF08590.10 KEY67636.1 - 2.8e-12 46.8 6.1 2.8e-09 37.2 2.3 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KEY67636.1 - 1.3e-07 31.4 7.4 2.7e-05 24.1 0.4 2.8 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KEY67636.1 - 1.9e-06 28.2 0.0 5.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KEY67636.1 - 2e-05 24.4 2.0 0.0019 18.0 0.3 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KEY67636.1 - 0.00089 19.6 4.9 0.21 12.1 0.8 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KEY67636.1 - 0.0014 18.4 10.5 0.012 15.4 0.3 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger Eryth_link_C PF16915.5 KEY67636.1 - 0.19 11.7 0.1 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus zf-CCCH_3 PF15663.5 KEY67636.1 - 0.6 10.3 2.5 18 5.6 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KEY67636.1 - 1.5 9.5 5.0 4 8.2 0.4 2.3 1 1 1 2 2 2 0 Torus domain HBS1_N PF08938.10 KEY67636.1 - 2.2 8.7 5.4 2.5 8.5 0.0 3.1 3 0 0 3 3 3 0 HBS1 N-terminus Abhydrolase_1 PF00561.20 KEY67638.1 - 2.4e-13 50.3 0.2 3.7e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY67638.1 - 2.9e-09 36.6 0.0 4.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY67638.1 - 0.0054 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEY67638.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 KEY67638.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 BTB PF00651.31 KEY67639.1 - 5.8e-06 26.5 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 KEY67640.1 - 1.7e-17 63.7 0.0 1.4e-16 60.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEY67640.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY67640.1 - 1.2e-05 25.6 0.0 6.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KEY67640.1 - 0.0071 16.9 0.0 0.023 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_5 PF07728.14 KEY67640.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Med22 PF06179.12 KEY67641.1 - 1.4e-06 28.5 0.0 5.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex Agro_virD5 PF04730.12 KEY67641.1 - 0.033 12.7 0.3 0.036 12.6 0.3 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein PseudoU_synth_1 PF01416.20 KEY67642.1 - 2.6e-07 31.1 0.0 4.1e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KEY67642.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Vesiculo_matrix PF06326.12 KEY67643.1 - 0.027 14.2 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein Shisa PF13908.6 KEY67643.1 - 5 7.3 9.1 6 7.1 5.0 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CHZ PF09649.10 KEY67644.1 - 0.002 17.6 2.3 0.0044 16.5 2.3 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ WD40 PF00400.32 KEY67645.1 - 5.4e-42 141.0 18.3 2e-08 34.7 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KEY67645.1 - 1.3e-13 50.6 0.4 1.3e-13 50.6 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY67645.1 - 1.1e-11 44.3 0.7 3.5e-11 42.7 0.4 2.0 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KEY67645.1 - 1.6e-09 37.9 0.5 0.0026 18.0 0.0 5.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY67645.1 - 8.5e-09 34.6 5.2 0.03 13.0 0.1 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KEY67645.1 - 0.00057 19.3 0.3 0.0034 16.8 0.3 1.9 2 0 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 KEY67645.1 - 0.0012 18.7 0.1 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 F-box FlaG PF03646.15 KEY67645.1 - 0.42 10.8 1.8 8.8 6.6 0.0 3.0 3 0 0 3 3 3 0 FlaG protein Mito_carr PF00153.27 KEY67646.1 - 1.9e-66 220.0 1.6 2.6e-22 78.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 KEY67647.1 - 9.4e-35 119.0 0.0 1.7e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WSC PF01822.19 KEY67648.1 - 8.8e-05 22.6 2.9 0.00015 21.9 2.9 1.4 1 0 0 1 1 1 1 WSC domain Ribosomal_S7e PF01251.18 KEY67649.1 - 3.7e-82 274.5 0.2 4.4e-82 274.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 KEY67650.1 - 1.8e-199 663.5 7.1 6.9e-199 661.6 7.1 1.7 1 1 0 1 1 1 1 Dynactin p62 family Hamartin PF04388.12 KEY67651.1 - 1.1 7.8 4.9 1.7 7.2 4.9 1.2 1 0 0 1 1 1 0 Hamartin protein MGC-24 PF05283.11 KEY67651.1 - 3.6 8.0 5.6 10 6.5 5.6 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1180 PF06679.12 KEY67652.1 - 1.2 9.5 4.8 18 5.7 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF924 PF06041.11 KEY67653.1 - 6.6e-55 186.0 0.0 8e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Peripla_BP_3 PF13377.6 KEY67653.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain ADH_zinc_N PF00107.26 KEY67654.1 - 3.1e-12 46.6 0.0 5.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY67654.1 - 1.3e-09 37.8 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY67654.1 - 0.0048 17.9 0.0 0.011 16.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SnoaL PF07366.12 KEY67655.1 - 0.00056 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY67655.1 - 0.0011 19.5 0.0 0.0031 18.1 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KEY67656.1 - 1.9e-40 138.9 69.1 1.2e-37 129.7 65.9 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY67656.1 - 1.7e-10 39.9 25.4 2.8e-10 39.3 25.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEY67656.1 - 2.3e-06 26.7 15.5 2.3e-06 26.7 15.5 3.9 3 2 0 3 3 3 1 Sugar (and other) transporter Spore_YtfJ PF09579.10 KEY67656.1 - 0.014 15.5 0.1 0.039 14.1 0.1 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) OATP PF03137.20 KEY67656.1 - 0.61 8.3 12.0 1.4 7.1 3.0 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RsbRD_N PF14361.6 KEY67657.1 - 0.097 13.4 0.7 0.32 11.7 0.7 1.8 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4083 PF13314.6 KEY67657.1 - 0.099 12.6 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Zn_clus PF00172.18 KEY67657.1 - 0.45 10.7 14.1 0.81 9.9 14.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEY67658.1 - 3.6e-53 181.0 0.0 4.8e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phage_FRD3 PF05798.11 KEY67658.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage FRD3 protein PHO4 PF01384.20 KEY67659.1 - 8.3e-101 337.4 18.0 9.5e-101 337.2 18.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KEY67659.1 - 0.45 10.8 9.4 1.3 9.4 1.0 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 ABC_tran PF00005.27 KEY67661.1 - 8e-47 159.2 0.0 4.4e-27 95.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY67661.1 - 7.2e-24 84.9 10.9 7.2e-24 84.9 10.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY67661.1 - 3.9e-11 42.8 0.5 0.0021 17.5 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEY67661.1 - 4.4e-08 33.3 0.6 1.2 8.9 0.0 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEY67661.1 - 1.1e-06 28.7 1.7 0.08 12.8 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KEY67661.1 - 3.5e-06 26.6 1.0 0.15 11.8 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KEY67661.1 - 1.7e-05 24.0 0.2 0.055 12.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.17 KEY67661.1 - 5.6e-05 22.9 0.1 2.3 7.9 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KEY67661.1 - 0.00079 19.5 0.0 0.4 10.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEY67661.1 - 0.0012 18.3 0.1 0.2 11.0 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KEY67661.1 - 0.0031 17.8 1.1 4.5 7.5 0.4 3.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEY67661.1 - 0.0039 17.7 0.4 2.2 8.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY67661.1 - 0.01 16.2 0.0 1.5 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEY67661.1 - 0.021 13.7 0.0 3.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KEY67661.1 - 0.03 13.8 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KEY67661.1 - 0.032 13.8 0.2 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KEY67661.1 - 0.037 14.3 0.5 4.1 7.7 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KEY67661.1 - 0.058 13.1 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Dodecin PF07311.12 KEY67661.1 - 0.058 13.6 0.2 0.19 12.0 0.2 1.8 1 0 0 1 1 1 0 Dodecin Dynamin_N PF00350.23 KEY67661.1 - 0.077 13.1 1.7 4.1 7.4 0.3 2.5 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 KEY67661.1 - 0.12 12.4 0.8 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DEAD PF00270.29 KEY67661.1 - 0.15 11.8 0.1 4.3 7.1 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KEY67661.1 - 0.23 10.6 2.0 2.1 7.5 0.0 3.0 3 1 0 3 3 3 0 NB-ARC domain UPF0052 PF01933.18 KEY67663.1 - 1.6e-66 224.6 0.0 2e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cwf_Cwc_15 PF04889.12 KEY67664.1 - 7.1 6.3 22.2 0.079 12.7 6.4 2.4 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Beta-lactamase PF00144.24 KEY67665.1 - 1.4e-42 146.2 3.4 2.3e-42 145.4 3.4 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KEY67665.1 - 0.00011 22.6 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) NTF2 PF02136.20 KEY67666.1 - 3e-31 108.5 0.1 3.3e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KEY67666.1 - 0.0026 17.7 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF4440 PF14534.6 KEY67666.1 - 0.043 14.2 0.0 0.052 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ribosomal_L7Ae PF01248.26 KEY67667.1 - 1.4e-21 76.0 0.3 2.5e-21 75.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KEY67667.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 CLPTM1 PF05602.12 KEY67667.1 - 0.083 11.9 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) ATP_bind_3 PF01171.20 KEY67668.1 - 2.5e-18 66.5 0.0 4.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KEY67668.1 - 7.4e-16 57.4 4.4 7.4e-16 57.4 4.4 3.3 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KEY67668.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.14 KEY67668.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) MWFE PF15879.5 KEY67669.1 - 4.9e-23 81.0 0.0 5.9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 KEY67670.1 - 4.6e-75 251.2 0.0 6.9e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEY67670.1 - 3.6e-20 71.3 3.4 3.6e-20 71.3 3.4 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain PHD_4 PF16866.5 KEY67670.1 - 6.6e-09 35.7 8.4 2.1e-08 34.1 8.4 1.9 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KEY67670.1 - 9.8e-05 22.2 10.1 9.8e-05 22.2 10.1 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KEY67670.1 - 0.025 14.1 1.3 0.074 12.6 1.3 1.9 1 0 0 1 1 1 0 PHD-finger zf-MIZ PF02891.20 KEY67670.1 - 0.049 13.4 1.8 0.1 12.4 1.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Acetyltransf_7 PF13508.7 KEY67670.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OrfB_Zn_ribbon PF07282.11 KEY67670.1 - 0.53 10.3 2.9 9.5 6.2 1.5 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 KEY67670.1 - 5.4 7.1 6.4 6.9 6.8 0.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-4CXXC_R1 PF10497.9 KEY67670.1 - 7.9 6.8 9.0 0.67 10.2 4.0 1.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Nup96 PF12110.8 KEY67671.1 - 1.8e-92 309.6 1.5 2.6e-92 309.0 1.5 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KEY67671.1 - 4e-51 173.0 0.0 2.2e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KEY67671.1 - 1.8e-29 102.4 320.0 3.2e-10 40.7 38.6 10.5 3 2 7 10 10 10 7 Nucleoporin FG repeat region EF-hand_7 PF13499.6 KEY67672.1 - 5e-19 68.5 9.6 1.1e-12 48.2 3.1 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KEY67672.1 - 7.3e-15 54.6 9.5 2.9e-10 39.8 3.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KEY67672.1 - 7.5e-15 53.3 7.6 9.8e-06 24.8 0.6 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KEY67672.1 - 1e-12 46.8 4.8 0.00012 21.7 0.3 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KEY67672.1 - 6.2e-08 31.8 4.0 0.00013 21.3 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KEY67672.1 - 0.00063 20.0 0.1 0.0091 16.3 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 KEY67672.1 - 0.079 13.3 0.0 1.2 9.5 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain ENTH PF01417.20 KEY67673.1 - 1.5e-50 170.5 0.1 2.3e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KEY67673.1 - 8.7e-05 22.2 10.3 0.0024 17.7 2.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 KEY67673.1 - 0.029 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 ANTH domain DUF4264 PF14084.6 KEY67673.1 - 0.031 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) VHS PF00790.19 KEY67673.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain AIDA PF16168.5 KEY67673.1 - 0.14 12.2 0.2 0.37 10.9 0.2 1.6 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk AA_permease_2 PF13520.6 KEY67674.1 - 1.3e-65 222.0 36.7 2e-65 221.3 36.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY67674.1 - 4.4e-16 58.5 30.7 9.5e-16 57.4 30.7 1.5 1 0 0 1 1 1 1 Amino acid permease SafA PF17073.5 KEY67674.1 - 0.089 12.7 0.0 0.44 10.5 0.0 2.2 1 0 0 1 1 1 0 Two-component-system connector protein Ni_hydr_CYTB PF01292.20 KEY67674.1 - 0.14 11.7 16.1 0.19 11.3 1.9 4.0 4 1 0 4 4 4 0 Prokaryotic cytochrome b561 FixP_N PF14715.6 KEY67674.1 - 0.18 11.6 0.1 0.18 11.6 0.1 4.5 5 0 0 5 5 5 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Mito_carr PF00153.27 KEY67676.1 - 2.5e-51 171.5 0.6 2.1e-18 66.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RCC1 PF00415.18 KEY67677.1 - 6.8e-21 74.6 0.2 2.9e-05 24.6 0.1 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KEY67677.1 - 4.2e-18 65.6 0.0 3.6e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KEY67677.1 - 2.2e-10 40.9 0.2 9.8e-10 38.8 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY67677.1 - 4.7e-06 27.1 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KEY67677.1 - 7.1e-06 25.7 1.1 7.1e-06 25.7 1.1 4.7 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 KEY67677.1 - 8.7e-06 25.7 0.3 0.087 13.4 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KEY67677.1 - 0.0024 18.2 2.1 3.3 8.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KEY67677.1 - 0.049 14.0 0.1 0.19 12.1 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ATG13 PF10033.9 KEY67678.1 - 8.7e-76 254.8 0.0 1.3e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 KEY67679.1 - 2.3e-36 124.7 0.1 5.2e-36 123.6 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KEY67679.1 - 3.8e-16 58.4 0.4 1.1e-15 56.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KEY67679.1 - 1.7e-14 53.2 0.0 3.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KEY67679.1 - 5.5e-14 51.7 0.0 1.7e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KEY67679.1 - 7.3e-11 42.2 1.5 2.1e-10 40.8 1.5 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KEY67679.1 - 0.0073 16.2 4.0 0.017 15.0 4.0 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif CRM1_C PF08767.11 KEY67679.1 - 0.2 10.8 0.3 17 4.4 0.0 2.1 2 0 0 2 2 2 0 CRM1 C terminal DUF4375 PF14300.6 KEY67679.1 - 1.7 8.9 3.6 4 7.7 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PEPCK_ATP PF01293.20 KEY67680.1 - 7.8e-214 710.6 0.0 1e-213 710.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SNF2_N PF00176.23 KEY67680.1 - 2.8e-65 220.3 1.2 8.9e-64 215.4 1.2 2.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY67680.1 - 1.7e-18 67.0 0.2 6.4e-18 65.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67680.1 - 3.5e-05 23.9 0.0 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEY67680.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KEY67680.1 - 0.071 12.0 0.1 0.19 10.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 GTP_EFTU PF00009.27 KEY67681.1 - 1.6e-42 145.3 0.0 2.8e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEY67681.1 - 1.1e-30 106.2 0.1 3e-30 104.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEY67681.1 - 1e-08 35.4 0.5 2.8e-08 34.0 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY67681.1 - 0.004 17.2 0.0 0.02 15.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Trnau1ap PF17654.1 KEY67681.1 - 4.6 8.1 17.1 20 6.1 17.1 2.1 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Ran-binding PF05508.11 KEY67682.1 - 6.5e-100 334.1 0.0 1.5e-98 329.6 0.0 2.1 1 1 0 1 1 1 1 RanGTP-binding protein Cupin_8 PF13621.6 KEY67684.1 - 8e-25 88.0 0.0 9e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KEY67684.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KEY67684.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.7 1 1 0 1 1 1 0 JmjC domain, hydroxylase Smg4_UPF3 PF03467.15 KEY67684.1 - 0.21 11.6 0.0 0.32 11.0 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family CK_II_beta PF01214.18 KEY67685.1 - 2.4e-74 249.1 0.0 4.7e-74 248.1 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 KEY67685.1 - 0.063 14.3 11.3 0.056 14.4 6.1 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KEY67685.1 - 0.071 11.6 1.5 0.11 11.1 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 KEY67685.1 - 0.62 8.1 1.5 0.82 7.7 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KEY67685.1 - 1 7.6 5.2 1.8 6.8 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KEY67685.1 - 2.2 8.0 4.8 0.62 9.8 1.3 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 KEY67685.1 - 2.3 7.9 9.0 0.89 9.2 5.9 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KEY67685.1 - 6.3 4.8 5.5 9.8 4.1 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi POB3_N PF17292.2 KEY67687.1 - 0.0093 16.4 0.0 21 5.6 0.0 3.1 3 0 0 3 3 3 1 POB3-like N-terminal PH domain NQR2_RnfD_RnfE PF03116.15 KEY67687.1 - 0.053 12.9 0.0 49 3.2 0.0 3.0 3 0 0 3 3 3 0 NQR2, RnfD, RnfE family CDC48_2 PF02933.17 KEY67687.1 - 0.083 12.7 0.0 18 5.2 0.0 3.0 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 DUF3752 PF12572.8 KEY67687.1 - 0.11 13.0 0.2 16 6.0 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3752) UCH_1 PF13423.6 KEY67688.1 - 4.5e-85 286.1 0.5 1.7e-81 274.3 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KEY67688.1 - 1.5e-22 80.9 0.0 2.8e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KEY67688.1 - 8.3e-07 28.7 0.0 2.7e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_31 PF13847.6 KEY67688.1 - 3.8e-06 26.8 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY67688.1 - 5.4e-06 27.0 0.0 1.4e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY67688.1 - 5.3e-05 23.9 0.0 0.00013 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KEY67688.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KEY67688.1 - 0.095 13.4 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KEY67690.1 - 3.8e-08 33.3 12.8 5.9e-08 32.7 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY67690.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.18 KEY67691.1 - 4.5e-19 67.6 0.1 4.5e-19 67.6 0.1 3.1 1 1 2 3 3 3 1 Copper fist DNA binding domain Leu_leader PF08054.11 KEY67691.1 - 0.21 11.2 0.2 7.2 6.3 0.1 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide VESA1_N PF12785.7 KEY67691.1 - 3.4 6.6 13.1 4.6 6.1 13.1 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 ApbA PF02558.16 KEY67692.1 - 3.7e-33 114.3 0.0 4.9e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEY67692.1 - 3.4e-24 85.4 0.0 5.6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.22 KEY67692.1 - 0.056 14.3 0.1 0.088 13.6 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.27 KEY67692.1 - 0.069 13.7 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 KEY67693.1 - 2.7e-19 69.7 0.5 7.5e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY67693.1 - 4.6e-16 59.0 0.0 1.4e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KEY67693.1 - 4.1e-13 50.1 0.0 1.1e-12 48.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KEY67693.1 - 5.6e-13 48.7 1.4 2.3e-12 46.8 1.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 KEY67693.1 - 8e-10 38.3 0.0 2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region PAS_2 PF08446.11 KEY67693.1 - 1.4e-09 38.6 0.0 4.6e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEY67693.1 - 0.0038 17.5 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.6 KEY67693.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KEY67693.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold ABC_tran PF00005.27 KEY67694.1 - 1.3e-46 158.5 0.5 4.7e-24 85.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEY67694.1 - 2.2e-21 77.0 2.1 3.9e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KEY67694.1 - 3.9e-21 75.6 50.2 1.3e-10 40.9 19.9 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KEY67694.1 - 6.5e-11 41.8 0.8 0.00022 20.9 0.2 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KEY67694.1 - 1.9e-08 34.0 1.4 0.072 12.5 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEY67694.1 - 7.5e-07 29.8 3.1 0.013 16.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEY67694.1 - 1.3e-05 25.1 0.1 0.32 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY67694.1 - 2.8e-05 24.1 0.3 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 KEY67694.1 - 0.00022 20.9 0.6 0.31 10.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY67694.1 - 0.00061 20.2 0.5 2.2 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KEY67694.1 - 0.014 15.1 3.2 4.5 6.9 0.4 3.5 3 1 0 3 3 3 0 AAA domain DUF4162 PF13732.6 KEY67694.1 - 0.018 15.7 0.0 1.5 9.6 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 KEY67694.1 - 0.023 15.0 0.1 16 5.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 KEY67694.1 - 0.034 13.9 0.8 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal IstB_IS21 PF01695.17 KEY67694.1 - 0.051 13.3 0.1 55 3.4 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 KEY67694.1 - 0.059 13.0 0.8 9.7 5.8 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEY67694.1 - 0.073 12.6 1.0 16 5.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KEY67694.1 - 0.093 13.0 0.7 5.8 7.1 0.6 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEY67694.1 - 0.099 13.0 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KEY67694.1 - 0.12 12.9 0.1 25 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEY67694.1 - 0.13 11.5 0.4 14 4.9 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KEY67694.1 - 0.16 12.1 0.4 48 4.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KEY67694.1 - 0.32 11.1 1.0 26 4.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KEY67694.1 - 0.66 10.1 2.6 46 4.1 0.7 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Fungal_trans PF04082.18 KEY67695.1 - 6.2e-11 41.8 0.1 1.4e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67695.1 - 2.7e-07 30.6 12.3 4.6e-07 29.9 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.6 KEY67696.1 - 0.089 13.1 0.1 0.089 13.1 0.1 4.5 4 2 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEY67696.1 - 1.9 8.7 24.7 0.7 10.1 2.3 6.3 4 2 0 4 4 4 0 Myb-like DNA-binding domain Arginosuc_synth PF00764.19 KEY67697.1 - 3.8e-129 431.4 0.0 2.2e-82 277.4 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase QueC PF06508.13 KEY67697.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KEY67697.1 - 0.17 10.6 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase Hemerythrin PF01814.23 KEY67698.1 - 5.4e-10 40.0 2.6 8e-10 39.4 2.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chal_sti_synt_N PF00195.19 KEY67699.1 - 1.2e-23 83.7 0.1 1.9e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KEY67699.1 - 1.4e-21 77.1 0.0 2.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 KEY67699.1 - 2.2e-06 27.2 0.0 3.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 KEY67699.1 - 0.0014 18.7 0.0 0.0076 16.4 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KEY67699.1 - 0.0026 17.6 0.1 0.007 16.2 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TRAUB PF08164.12 KEY67701.1 - 1.2e-30 105.8 0.3 3.5e-30 104.4 0.3 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KEY67701.1 - 3.5e-27 95.8 0.1 3.5e-27 95.8 0.1 3.0 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TEX33 PF15400.6 KEY67701.1 - 0.046 14.2 0.3 0.13 12.8 0.3 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family COX16 PF14138.6 KEY67701.1 - 0.5 10.9 2.4 1 9.9 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 ParA PF10609.9 KEY67702.1 - 3e-94 315.1 0.1 3.5e-94 314.8 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEY67702.1 - 4.6e-10 39.6 0.0 1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEY67702.1 - 1.2e-08 35.1 0.2 2.9e-06 27.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 KEY67702.1 - 0.00026 20.3 0.3 0.006 15.8 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 KEY67702.1 - 0.00032 20.1 0.1 0.00044 19.6 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 KEY67702.1 - 0.0014 18.5 0.7 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KEY67702.1 - 0.012 15.1 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KEY67702.1 - 0.023 14.1 0.0 0.47 9.9 0.0 2.2 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KEY67702.1 - 0.048 13.2 0.2 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Tudor_3 PF18115.1 KEY67703.1 - 1.1e-07 31.5 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KEY67703.1 - 0.00029 20.8 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 KEY67703.1 - 0.0041 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 KEY67703.1 - 0.024 14.4 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TCO89 PF10452.9 KEY67704.1 - 0.00012 21.2 15.6 0.00033 19.8 0.5 3.3 3 0 0 3 3 3 2 TORC1 subunit TCO89 ABC1 PF03109.16 KEY67705.1 - 8.3e-23 80.8 0.0 2.2e-13 50.4 0.0 2.7 3 0 0 3 3 3 2 ABC1 family APH PF01636.23 KEY67705.1 - 0.024 14.6 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family POTRA_TamA_1 PF17243.2 KEY67705.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Cyto_heme_lyase PF01265.17 KEY67706.1 - 3.7e-124 414.1 0.8 4.8e-124 413.7 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase RIIa PF02197.17 KEY67707.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DbpA PF03880.15 KEY67707.1 - 0.5 10.4 0.1 0.5 10.4 0.1 2.2 3 0 0 3 3 3 0 DbpA RNA binding domain Fungal_trans PF04082.18 KEY67709.1 - 1.2e-13 50.7 1.4 3.3e-13 49.3 1.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67709.1 - 2.6e-05 24.3 7.3 4.2e-05 23.6 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KEY67710.1 - 1.5e-79 267.6 0.0 1.8e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III RP-C_C PF11800.8 KEY67710.1 - 0.26 11.4 0.3 0.88 9.6 0.0 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region p450 PF00067.22 KEY67711.1 - 6.9e-41 140.5 0.0 8.9e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BUD22 PF09073.10 KEY67712.1 - 9e-95 318.5 27.6 1e-94 318.4 27.6 1.0 1 0 0 1 1 1 1 BUD22 adh_short_C2 PF13561.6 KEY67713.1 - 1.8e-32 112.8 0.0 9.2e-32 110.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY67713.1 - 2.4e-27 95.7 0.1 2.4e-27 95.7 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY67713.1 - 3.7e-05 23.7 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Mito_carr PF00153.27 KEY67714.1 - 8.3e-52 173.1 5.6 2.4e-18 65.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY67714.1 - 0.025 13.7 0.7 0.24 10.5 0.1 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease COX7C PF02935.16 KEY67714.1 - 0.048 13.9 0.2 0.79 10.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Tir_receptor_N PF07490.11 KEY67714.1 - 0.2 11.4 1.9 0.4 10.5 1.9 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Rad4 PF03835.15 KEY67715.1 - 6.6e-30 103.7 0.5 1.8e-29 102.4 0.5 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KEY67715.1 - 1.4e-29 102.3 0.2 3.1e-29 101.2 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KEY67715.1 - 1.4e-22 79.2 0.0 3.2e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KEY67715.1 - 1.9e-19 70.3 0.9 1.9e-19 70.3 0.9 3.3 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KEY67715.1 - 0.00036 21.0 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily SURF6 PF04935.12 KEY67715.1 - 2.2 8.1 7.9 4.9 6.9 7.9 1.5 1 0 0 1 1 1 0 Surfeit locus protein 6 RRM_1 PF00076.22 KEY67717.1 - 1.1e-09 38.0 0.0 2.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY67717.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEY67717.1 - 0.0051 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF2046 PF09755.9 KEY67718.1 - 0.035 13.3 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF2046 PF09755.9 KEY67720.1 - 0.0012 18.2 0.3 0.033 13.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.12 KEY67720.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.6 3 0 0 3 3 3 0 Striatin family Fez1 PF06818.15 KEY67720.1 - 0.23 11.9 2.8 0.54 10.7 0.1 2.1 2 0 0 2 2 2 0 Fez1 FlaC_arch PF05377.11 KEY67720.1 - 0.62 10.5 2.2 0.5 10.8 0.3 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KEY67721.1 - 5e-07 30.1 109.8 0.054 13.7 13.2 7.8 3 1 5 8 8 8 6 Autophagy protein 16 (ATG16) GAS PF13851.6 KEY67721.1 - 7.4e-05 22.2 93.1 0.00044 19.7 19.1 7.1 3 1 3 7 7 7 5 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KEY67721.1 - 0.00014 21.8 62.8 0.0041 17.1 2.4 8.3 4 2 3 9 9 9 6 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KEY67721.1 - 0.00068 19.3 97.9 0.002 17.8 5.1 6.7 2 1 5 7 7 7 4 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 KEY67721.1 - 0.0018 16.6 9.5 0.0018 16.6 9.5 5.2 2 1 1 5 5 5 2 Septation ring formation regulator, EzrA KASH_CCD PF14662.6 KEY67721.1 - 0.0025 17.7 13.3 0.0025 17.7 13.3 6.8 2 1 6 8 8 8 4 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KEY67721.1 - 0.012 16.1 12.0 0.012 16.1 12.0 6.5 1 1 3 5 5 4 0 Fez1 Fib_alpha PF08702.10 KEY67721.1 - 0.035 14.3 65.2 0.75 10.0 7.7 7.5 2 1 5 8 8 8 0 Fibrinogen alpha/beta chain family MAD PF05557.13 KEY67721.1 - 0.061 11.7 86.3 0.0096 14.3 37.2 4.3 2 1 3 5 5 5 0 Mitotic checkpoint protein Cortex-I_coil PF09304.10 KEY67721.1 - 0.46 10.7 0.0 0.46 10.7 0.0 8.1 3 2 6 9 9 7 0 Cortexillin I, coiled coil CT_C_D PF02682.16 KEY67721.1 - 0.69 9.6 7.7 0.18 11.5 0.2 3.4 3 0 0 3 3 3 0 Carboxyltransferase domain, subdomain C and D CCDC92 PF14916.6 KEY67721.1 - 1.3 8.8 13.8 0.066 13.0 4.7 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.11 KEY67721.1 - 1.5 8.7 5.8 8.5 6.3 0.0 4.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF3450 PF11932.8 KEY67721.1 - 1.8 7.8 65.4 0.48 9.7 0.9 7.4 2 1 3 6 6 6 0 Protein of unknown function (DUF3450) PWI PF01480.17 KEY67722.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 PWI domain HgmA PF04209.13 KEY67724.1 - 5e-190 631.7 0.0 5.7e-190 631.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase APG17 PF04108.12 KEY67725.1 - 0.23 10.5 2.7 0.18 10.8 0.3 2.0 3 0 0 3 3 3 0 Autophagy protein Apg17 UQ_con PF00179.26 KEY67728.1 - 3.7e-20 72.0 0.0 5.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY67728.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Bac_surface_Ag PF01103.23 KEY67729.1 - 7.4e-41 140.7 0.0 9.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KEY67729.1 - 0.036 13.5 0.1 7 6.0 0.0 2.3 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB ABC2_membrane PF01061.24 KEY67730.1 - 7.1e-89 296.8 52.6 1.5e-44 152.0 25.4 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY67730.1 - 1.2e-33 116.5 0.0 2.2e-16 60.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY67730.1 - 6.4e-29 99.7 13.4 1e-25 89.4 0.0 4.5 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY67730.1 - 4e-15 56.2 0.0 3.2e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY67730.1 - 2.1e-06 28.2 0.1 0.00041 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KEY67730.1 - 9.9e-06 25.3 0.0 0.00033 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY67730.1 - 2.2e-05 25.0 0.0 0.0043 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY67730.1 - 2.8e-05 24.1 0.0 0.0028 17.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEY67730.1 - 8.8e-05 22.2 0.8 0.016 15.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KEY67730.1 - 0.00013 22.1 0.2 0.029 14.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.7 KEY67730.1 - 0.00035 19.8 42.5 0.0028 16.8 14.2 3.4 2 2 2 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 KEY67730.1 - 0.0011 18.9 0.1 2.1 8.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEY67730.1 - 0.0024 18.2 0.2 0.29 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEY67730.1 - 0.0085 15.7 0.3 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KEY67730.1 - 0.0091 16.4 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEY67730.1 - 0.02 14.3 0.0 7.1 6.0 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEY67730.1 - 0.038 13.9 0.7 3.6 7.5 0.1 2.9 3 0 0 3 3 2 0 NACHT domain AAA_30 PF13604.6 KEY67730.1 - 0.071 12.8 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEY67730.1 - 0.12 12.8 0.1 0.35 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEY67730.1 - 0.19 12.2 0.0 24 5.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEY67730.1 - 0.21 11.3 0.9 6.3 6.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain DUF1072 PF06380.11 KEY67730.1 - 0.32 10.9 2.6 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Retinal PF15449.6 KEY67731.1 - 1.1 7.0 5.7 1.2 6.8 5.7 1.0 1 0 0 1 1 1 0 Retinal protein HET PF06985.11 KEY67735.1 - 2.5e-09 37.7 0.0 5.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 KEY67736.1 - 1.1e-58 199.0 0.0 1.4e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY67736.1 - 4.4e-26 92.1 0.0 6.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY67736.1 - 5.9e-05 23.2 0.1 0.00024 21.3 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY67736.1 - 0.00037 19.8 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEY67736.1 - 0.00051 19.2 0.0 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY67736.1 - 0.004 16.4 0.0 0.0082 15.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY67736.1 - 0.014 15.0 0.9 0.025 14.2 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY67736.1 - 0.015 14.4 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KEY67736.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KEY67736.1 - 0.037 14.0 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEY67736.1 - 0.097 13.2 0.1 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY67736.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KEY67736.1 - 0.17 11.1 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tmemb_14 PF03647.13 KEY67737.1 - 0.24 12.2 6.1 3.3 8.5 0.1 2.8 2 1 1 3 3 3 0 Transmembrane proteins 14C 7TM_GPCR_Srh PF10318.9 KEY67737.1 - 0.29 10.1 12.0 0.28 10.2 10.6 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh adh_short PF00106.25 KEY67739.1 - 1.9e-23 82.9 0.0 3.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67739.1 - 2.6e-23 82.8 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67739.1 - 8.3e-07 29.1 0.1 1.3e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF460 PF04312.13 KEY67739.1 - 0.00032 20.4 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) MlaE PF02405.16 KEY67739.1 - 0.077 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Permease MlaE Aldo_ket_red PF00248.21 KEY67740.1 - 3.1e-63 213.7 0.0 3.8e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase PF00702.26 KEY67740.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 KEY67741.1 - 1.3e-09 37.4 5.5 1.9e-09 36.8 5.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67741.1 - 0.00013 22.0 2.8 0.00013 22.0 2.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 KEY67742.1 - 7.8e-18 64.5 25.2 2.1e-05 24.7 1.0 5.0 2 1 4 6 6 6 6 Tetratricopeptide repeat Patatin PF01734.22 KEY67742.1 - 1.9e-14 54.3 0.1 1.2e-13 51.7 0.0 2.3 2 1 0 2 2 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KEY67742.1 - 8.4e-12 44.8 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KEY67742.1 - 4.5e-10 39.1 26.2 0.00079 19.2 0.4 7.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY67742.1 - 1.7e-07 30.8 10.8 0.068 13.2 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY67742.1 - 3.4e-07 29.9 18.1 0.68 10.2 0.4 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat AAA_16 PF13191.6 KEY67742.1 - 1.2e-06 29.0 5.2 1.6e-05 25.4 0.2 3.2 2 1 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KEY67742.1 - 9e-06 26.1 21.2 0.087 13.3 1.3 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY67742.1 - 5.9e-05 22.7 7.7 2.6 8.0 0.2 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67742.1 - 0.00011 22.6 27.0 0.53 11.0 0.1 9.2 12 0 0 12 12 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY67742.1 - 0.00015 22.3 13.2 0.19 12.4 1.7 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67742.1 - 0.00021 21.8 16.1 7.4 7.7 0.0 7.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY67742.1 - 0.00024 21.1 13.5 0.61 10.4 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY67742.1 - 0.00033 20.8 8.7 1.5 9.1 0.4 5.1 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.6 KEY67742.1 - 0.00073 19.8 0.3 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEY67742.1 - 0.00087 19.1 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein SRP54 PF00448.22 KEY67742.1 - 0.0033 17.1 0.3 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KEY67742.1 - 0.0078 16.2 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PPR PF01535.20 KEY67742.1 - 0.011 15.9 0.2 51 4.4 0.0 4.9 5 0 0 5 5 4 0 PPR repeat AAA PF00004.29 KEY67742.1 - 0.1 13.0 0.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rieske PF00355.26 KEY67742.1 - 0.17 11.9 0.2 0.52 10.3 0.2 1.8 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain TPR_4 PF07721.14 KEY67742.1 - 0.18 12.5 8.9 2.1e+02 3.0 0.0 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KEY67743.1 - 5e-72 243.3 0.5 5.8e-72 243.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Acetyltransf_1 PF00583.25 KEY67745.1 - 0.00045 20.4 0.0 0.00089 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY67745.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY67745.1 - 0.014 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KEY67746.1 - 4e-52 177.3 14.5 4e-52 177.3 14.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY67746.1 - 1.1e-07 31.1 10.5 1.1e-07 31.1 10.5 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEY67746.1 - 1.2e-06 27.3 6.1 2.1e-06 26.5 6.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KEY67746.1 - 0.00043 18.8 2.8 0.00086 17.8 2.8 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KEY67746.1 - 0.14 10.4 5.3 0.1 10.8 0.8 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KEY67746.1 - 0.22 10.1 7.4 0.17 10.5 1.1 2.4 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Pox_A14 PF05767.12 KEY67746.1 - 0.24 11.6 3.2 40 4.5 0.0 4.1 5 0 0 5 5 5 0 Poxvirus virion envelope protein A14 p450 PF00067.22 KEY67747.1 - 4e-50 170.9 0.0 7.1e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.21 KEY67748.1 - 3e-78 263.4 5.7 3e-78 263.4 5.7 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KEY67748.1 - 5.1e-06 25.7 27.6 0.00028 19.9 27.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M14 PF00246.24 KEY67749.1 - 5.3e-14 52.7 0.0 1.2e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KEY67749.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family WSC PF01822.19 KEY67750.1 - 4.4e-15 55.6 4.1 7.2e-15 55.0 4.1 1.4 1 0 0 1 1 1 1 WSC domain PAN_3 PF08277.12 KEY67750.1 - 0.01 15.6 0.3 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain E1-E2_ATPase PF00122.20 KEY67751.1 - 4.7e-17 62.1 0.0 9.9e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEY67751.1 - 2.2e-15 57.5 4.2 3.9e-09 37.1 4.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY67751.1 - 0.00012 22.1 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY67751.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ldh_1_C PF02866.18 KEY67752.1 - 1.2e-46 158.7 0.0 2.3e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEY67752.1 - 3e-43 147.3 0.1 1.9e-42 144.7 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEY67752.1 - 0.00052 19.1 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2HC5 PF06221.13 KEY67753.1 - 4.5e-22 77.8 6.3 6.9e-22 77.2 6.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FYVE PF01363.21 KEY67753.1 - 0.1 12.7 0.8 0.18 12.0 0.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger ASFV_J13L PF05568.11 KEY67753.1 - 3.2 7.5 8.2 6.2 6.5 8.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Whi5 PF08528.11 KEY67754.1 - 9.7e-10 37.9 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Endostatin PF06482.11 KEY67754.1 - 2.6 7.4 9.2 0.22 10.9 3.1 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin HET PF06985.11 KEY67756.1 - 1.6e-27 96.7 0.2 3e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Intimin_C PF07979.11 KEY67756.1 - 0.091 13.2 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Intimin C-type lectin domain VWA PF00092.28 KEY67757.1 - 3e-06 27.6 0.0 4.1e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KEY67757.1 - 0.0009 18.7 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA_2 PF13519.6 KEY67757.1 - 0.0018 18.9 0.0 1.1 9.9 0.0 3.1 2 1 0 2 2 2 2 von Willebrand factor type A domain Myb_DNA-bind_5 PF13873.6 KEY67757.1 - 0.11 12.6 0.2 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_C1 PF00112.23 KEY67757.1 - 0.18 11.9 0.1 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Papain family cysteine protease Pro-kuma_activ PF09286.11 KEY67758.1 - 2.3e-21 76.6 0.0 5.5e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KEY67758.1 - 9.8e-06 25.0 0.0 9.8e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Subtilase family SIR2 PF02146.17 KEY67759.1 - 2.4e-34 118.8 0.1 3.6e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Sir2 family ADH_N PF08240.12 KEY67760.1 - 7.1e-08 32.3 0.1 5.5e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_5 PF00266.19 KEY67761.1 - 9.1e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V NAD_binding_8 PF13450.6 KEY67763.1 - 1.7e-10 40.9 0.2 4e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY67763.1 - 2.2e-08 33.6 1.1 3.7e-08 32.9 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY67763.1 - 2.9e-06 27.1 0.5 5.6e-06 26.2 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEY67763.1 - 7.6e-06 25.5 2.5 1.4e-05 24.6 2.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY67763.1 - 1.4e-05 24.0 0.6 2.4e-05 23.2 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEY67763.1 - 0.00019 20.8 0.5 0.00028 20.3 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY67763.1 - 0.00021 20.6 0.2 0.00046 19.5 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY67763.1 - 0.0025 18.4 0.6 0.0054 17.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY67763.1 - 0.0028 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY67763.1 - 0.019 14.2 0.2 0.054 12.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KEY67763.1 - 0.022 13.9 0.2 0.031 13.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEY67763.1 - 0.033 13.5 0.0 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase IlvN PF07991.12 KEY67763.1 - 0.049 13.2 0.2 0.14 11.7 0.2 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MCRA PF06100.11 KEY67763.1 - 0.086 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 KEY67763.1 - 0.21 10.4 1.4 0.39 9.5 1.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Beta-lactamase PF00144.24 KEY67764.1 - 1.1e-43 149.8 0.0 1.7e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KEY67764.1 - 1.1e-10 41.9 0.2 2.2e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 KEY67764.1 - 0.0026 17.4 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase enzyme family Pkip-1 PF06878.11 KEY67764.1 - 0.034 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Pkip-1 protein Glutaminase PF04960.15 KEY67765.1 - 1.6e-113 378.7 0.1 1.9e-113 378.4 0.1 1.1 1 0 0 1 1 1 1 Glutaminase Sugar_tr PF00083.24 KEY67767.1 - 5e-104 348.7 19.2 6.1e-104 348.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY67767.1 - 2.1e-27 96.0 15.7 2.1e-27 96.0 15.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 KEY67768.1 - 2.9e-16 59.7 0.0 6.2e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY67768.1 - 4.8e-13 48.8 0.0 8.2e-13 48.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEY67768.1 - 5.5e-12 45.9 0.1 9.7e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEY67768.1 - 3.6e-10 39.5 0.1 0.00016 20.9 0.0 2.4 3 0 0 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KEY67768.1 - 8.2e-10 38.6 0.1 1.4e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEY67768.1 - 9.5e-08 31.9 0.5 2.4e-06 27.3 0.5 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KEY67768.1 - 1.7e-05 24.1 0.3 2.4e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KEY67768.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY67768.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY67768.1 - 0.0013 19.0 0.2 0.0028 17.9 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KEY67768.1 - 0.0026 16.9 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DXP_reductoisom PF02670.16 KEY67768.1 - 0.046 14.4 0.4 0.085 13.6 0.4 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ADH_N PF08240.12 KEY67769.1 - 6.1e-26 90.4 2.6 9.4e-26 89.8 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY67769.1 - 4.5e-12 46.1 0.0 7.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY67769.1 - 0.0019 17.6 0.2 0.0035 16.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Y_Y_Y PF07495.13 KEY67769.1 - 0.019 14.9 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Y_Y_Y domain APH PF01636.23 KEY67771.1 - 5.3e-12 46.2 0.0 1.7e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Coatomer_b_Cpla PF14806.6 KEY67771.1 - 0.017 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Choline_kinase PF01633.20 KEY67771.1 - 0.053 13.1 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.18 KEY67772.1 - 1.2e-08 34.3 1.8 1.8e-07 30.5 1.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY67772.1 - 2e-06 27.8 4.5 3.5e-06 27.0 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 KEY67773.1 - 9.6e-46 156.1 0.1 1.4e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEY67773.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 KEY67774.1 - 7.5e-36 123.3 0.0 1.3e-35 122.6 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Kelch_6 PF13964.6 KEY67775.1 - 0.0026 18.0 0.8 1.2 9.5 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Romo1 PF10247.9 KEY67775.1 - 0.029 14.7 1.1 0.058 13.8 0.2 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF1206 PF06724.11 KEY67775.1 - 0.042 13.9 0.4 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) PDGLE PF13190.6 KEY67775.1 - 0.073 13.0 0.0 0.63 10.0 0.0 2.4 3 0 0 3 3 3 0 PDGLE domain DUF2157 PF09925.9 KEY67776.1 - 0.021 14.6 1.4 0.027 14.2 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Oxidored_q2 PF00420.24 KEY67776.1 - 0.073 12.7 2.5 0.24 11.0 0.0 2.2 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tyrosinase PF00264.20 KEY67777.1 - 5.6e-49 167.4 0.0 7.6e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SPOB_a PF14689.6 KEY67777.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Glyco_hydro_43 PF04616.14 KEY67778.1 - 2.4e-47 161.6 2.5 3.2e-47 161.2 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KEY67778.1 - 1.6e-38 131.8 3.7 1.6e-38 131.8 3.7 1.9 1 1 0 1 1 1 1 Carbohydrate binding module (family 6) CBM_1 PF00734.18 KEY67778.1 - 2.7e-10 40.0 18.0 1.3e-09 37.8 18.0 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF5010_C PF18099.1 KEY67778.1 - 4.7e-07 29.9 0.7 4.7e-07 29.9 0.7 1.9 2 0 0 2 2 2 1 DUF5010 C-terminal domain Toxin_7 PF05980.12 KEY67778.1 - 0.86 9.9 7.1 2.7 8.3 7.1 1.9 1 0 0 1 1 1 0 Toxin 7 APH PF01636.23 KEY67779.1 - 8.4e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KEY67779.1 - 0.0082 15.0 0.0 0.63 8.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KEY67779.1 - 0.039 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rieske_3 PF18465.1 KEY67779.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Rieske 3Fe-4S Ank_2 PF12796.7 KEY67781.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY67781.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY67781.1 - 0.13 12.9 0.0 37 5.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Peptidase_M36 PF02128.15 KEY67782.1 - 5.4e-143 476.6 0.0 7.1e-143 476.3 0.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KEY67782.1 - 2.5e-15 56.0 5.6 7.8e-15 54.5 5.6 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF4901 PF16244.5 KEY67782.1 - 0.13 11.6 0.0 0.94 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4901) TIM PF00121.18 KEY67786.1 - 4.8e-46 157.1 0.0 5.9e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Glyco_hydro_3_C PF01915.22 KEY67788.1 - 7.9e-50 169.6 0.4 1.2e-49 169.0 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY67788.1 - 9.9e-35 120.4 0.0 3.8e-34 118.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY67788.1 - 2e-26 91.9 0.0 4.5e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Asp PF00026.23 KEY67790.1 - 9.1e-61 206.0 0.1 1.1e-60 205.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY67790.1 - 9.5e-08 32.5 0.2 0.017 15.4 0.1 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY67790.1 - 0.00022 21.8 2.1 0.0028 18.3 0.7 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KEY67790.1 - 0.83 10.3 3.1 1.8 9.2 0.6 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease FSA_C PF10479.9 KEY67791.1 - 0.21 9.7 8.7 0.28 9.3 8.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAD_binding_4 PF01565.23 KEY67792.1 - 2.8e-24 85.4 1.4 1.4e-23 83.2 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY67792.1 - 1.2e-09 38.2 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.7 KEY67793.1 - 4.4e-53 177.8 2.8 5.9e-11 42.8 0.3 6.4 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY67793.1 - 4.4e-32 109.7 17.1 1.4e-05 25.2 0.2 10.2 5 4 5 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY67793.1 - 6.2e-32 109.6 9.8 5.1e-07 30.1 0.1 9.7 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KEY67793.1 - 7.6e-28 95.7 15.8 0.019 15.4 0.0 11.4 10 1 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KEY67793.1 - 2.4e-25 85.8 8.1 0.021 15.3 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat NACHT PF05729.12 KEY67793.1 - 0.0073 16.2 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Sulfate_transp PF00916.20 KEY67794.1 - 2.3e-77 260.3 10.6 2.3e-77 260.3 10.6 1.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KEY67794.1 - 1.3e-17 63.5 0.0 2.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KEY67794.1 - 0.00055 20.2 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 STAS domain Thiolase_N PF00108.23 KEY67795.1 - 1.2e-64 218.2 0.1 1.6e-64 217.8 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY67795.1 - 1.9e-41 140.5 0.1 4.5e-41 139.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEY67795.1 - 0.0083 15.7 1.5 0.021 14.4 1.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_cc PF11790.8 KEY67796.1 - 1e-67 228.2 0.0 1.2e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.20 KEY67798.1 - 1.6e-33 115.7 18.3 3.5e-28 98.4 0.7 3.8 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY67798.1 - 2.3e-30 105.7 4.8 2.3e-30 105.7 4.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KEY67798.1 - 1.2e-20 73.4 0.0 3.4e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEY67798.1 - 1.4e-18 68.0 0.4 1.5e-16 61.3 0.4 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY67798.1 - 1e-15 57.2 0.1 3.1e-15 55.6 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY67798.1 - 5.3e-07 29.6 2.6 9.1e-06 25.6 0.3 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pro_CA PF00484.19 KEY67799.1 - 2.6e-50 170.8 0.0 3.8e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF1996 PF09362.10 KEY67800.1 - 5.2e-68 229.5 0.7 6.1e-68 229.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Peptidase_S58 PF03576.14 KEY67801.1 - 2.3e-116 388.5 3.7 2.6e-116 388.3 3.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 Cas1_AcylT PF07779.12 KEY67802.1 - 2.2e-103 346.7 13.9 3.7e-103 346.0 13.9 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF5010 PF16402.5 KEY67805.1 - 0.062 12.1 0.0 0.065 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) RdRP PF05183.12 KEY67806.1 - 6.2e-179 596.4 0.0 8e-179 596.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase zf-C2H2 PF00096.26 KEY67807.1 - 0.0059 17.0 0.0 0.0059 17.0 0.0 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY67807.1 - 0.01 16.6 0.0 0.01 16.6 0.0 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger Ipi1_N PF12333.8 KEY67807.1 - 0.047 14.3 2.8 0.29 11.8 2.8 2.0 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation CpXC PF14353.6 KEY67807.1 - 0.049 13.7 0.6 0.11 12.6 0.4 1.7 1 1 0 1 1 1 0 CpXC protein UPF0547 PF10571.9 KEY67807.1 - 0.16 12.0 0.7 0.16 12.0 0.7 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_5 PF13719.6 KEY67807.1 - 0.4 10.5 0.1 0.4 10.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain GET2 PF08690.10 KEY67807.1 - 0.44 10.2 3.8 0.56 9.8 3.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Dabb PF07876.12 KEY67809.1 - 1.3e-26 93.1 0.2 1.4e-26 92.9 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DLH PF01738.18 KEY67809.1 - 0.06 12.9 0.2 0.069 12.7 0.2 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF3674 PF12426.8 KEY67809.1 - 0.064 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF4390 PF14334.6 KEY67809.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) FTA2 PF13095.6 KEY67811.1 - 2.9e-48 164.3 0.0 3.8e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KEY67811.1 - 0.019 14.3 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Palm_thioest PF02089.15 KEY67812.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 KEY67812.1 - 0.15 11.2 0.0 0.4 9.8 0.1 1.6 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Glyco_hydro_5_C PF18564.1 KEY67813.1 - 1.7e-19 70.1 0.1 3.6e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KEY67813.1 - 3.1e-12 46.5 0.0 1.3e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 KEY67814.1 - 3.6e-27 95.1 0.1 7.3e-23 81.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY67814.1 - 5.3e-15 55.6 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY67814.1 - 2.2e-05 24.5 0.1 3.9e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY67814.1 - 0.022 13.9 0.0 0.056 12.6 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEY67814.1 - 0.11 11.9 0.1 0.36 10.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ArAE_1_C PF11728.8 KEY67815.1 - 0.044 13.8 0.5 0.093 12.7 0.5 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain EutK_C PF16365.5 KEY67815.1 - 0.093 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Ribosomal_L17 PF01196.19 KEY67815.1 - 0.11 13.4 0.1 0.31 11.9 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L17 BPL_N PF09825.9 KEY67816.1 - 0.056 12.5 0.3 0.086 11.9 0.3 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Ceramidase_alk PF04734.13 KEY67817.1 - 9.2e-220 730.6 0.0 1.1e-219 730.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KEY67817.1 - 3.8e-58 196.1 0.0 5.8e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal UvrD-helicase PF00580.21 KEY67818.1 - 1.9e-65 221.5 0.6 1e-63 215.8 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEY67818.1 - 9.2e-62 209.4 0.4 5.3e-61 206.9 0.4 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEY67818.1 - 3.7e-32 111.7 0.0 8.9e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEY67818.1 - 6.7e-14 51.5 0.0 1.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEY67818.1 - 1.4e-10 41.2 0.3 4e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEY67818.1 - 1e-07 31.9 0.2 0.031 14.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KEY67818.1 - 6.3e-05 22.7 0.1 0.0012 18.5 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KEY67818.1 - 0.012 15.4 2.3 0.016 15.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain Terminase_6 PF03237.15 KEY67818.1 - 0.11 12.2 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Terminase-like family Helicase_RecD PF05127.14 KEY67818.1 - 0.14 12.0 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KEY67818.1 - 0.2 11.9 0.5 7.6 6.8 0.2 3.0 2 1 0 2 2 2 0 AAA domain CcmD PF04995.14 KEY67819.1 - 0.00017 21.6 0.8 0.29 11.2 0.1 2.4 2 0 0 2 2 2 2 Heme exporter protein D (CcmD) NADHdh_A3 PF14987.6 KEY67819.1 - 3.7 7.9 5.5 3.1 8.2 1.8 2.8 2 1 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Ribosomal_S7 PF00177.21 KEY67820.1 - 3.8e-25 88.3 0.0 5.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 KEY67821.1 - 6.3e-26 91.6 6.1 2.2e-24 86.6 3.5 3.1 2 1 0 2 2 2 1 Universal stress protein family GHMP_kinases_N PF00288.26 KEY67822.1 - 6.7e-17 61.5 0.0 2.6e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEY67822.1 - 3.3e-07 30.6 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KEY67822.1 - 0.0046 16.5 0.1 0.0087 15.6 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 KEY67823.1 - 7e-40 133.6 16.1 2.9e-08 33.2 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 KEY67823.1 - 0.11 12.5 4.0 0.93 9.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67823.1 - 0.23 12.2 1.1 0.57 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67823.1 - 0.76 10.8 5.0 9.9 7.3 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mtr2 PF10429.9 KEY67824.1 - 0.073 13.0 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.20 KEY67824.1 - 0.14 12.7 1.7 2.4 8.8 1.7 2.1 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.11 KEY67825.1 - 1.3e-93 313.9 1.3 4.5e-93 312.1 1.3 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEY67825.1 - 1e-20 73.6 5.6 1.9e-09 36.3 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.7 KEY67825.1 - 1.1e-15 58.5 0.0 1.7e-14 54.6 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.19 KEY67825.1 - 1.2e-09 38.0 0.0 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FR47 PF08445.10 KEY67825.1 - 0.0044 16.9 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KEY67825.1 - 0.055 13.7 0.2 0.22 11.8 0.2 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GrpB PF04229.14 KEY67826.1 - 1.7e-50 171.4 0.0 2e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Ribosomal_L34 PF00468.17 KEY67827.1 - 1.4e-11 44.2 9.6 2.5e-11 43.3 9.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3_C PF01915.22 KEY67828.1 - 2.5e-44 151.7 0.0 9e-44 149.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY67828.1 - 2.4e-42 145.4 0.0 3.6e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY67828.1 - 1.1e-22 79.9 0.2 2.1e-22 79.0 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KEY67828.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 CARDB DUF11 PF01345.18 KEY67828.1 - 0.047 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF11 Lipase_3 PF01764.25 KEY67829.1 - 2.9e-32 111.5 0.0 4.5e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY67829.1 - 9.7e-05 23.1 0.9 0.00019 22.1 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY67829.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KEY67829.1 - 0.051 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LRR_6 PF13516.6 KEY67830.1 - 0.0009 19.1 0.0 0.3 11.2 0.0 4.7 6 0 0 6 6 6 1 Leucine Rich repeat IL1_propep PF02394.16 KEY67830.1 - 0.3 12.0 2.4 5.4 8.0 0.4 3.1 2 1 0 3 3 3 0 Interleukin-1 propeptide SNF2_N PF00176.23 KEY67831.1 - 9.4e-49 166.0 0.0 2e-47 161.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY67831.1 - 5e-16 59.0 0.0 2.7e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67831.1 - 5.2e-07 29.8 0.6 1.2e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KEY67831.1 - 1.6e-06 27.8 10.2 1.6e-06 27.8 10.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY67831.1 - 0.002 17.9 9.9 0.002 17.9 9.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY67831.1 - 0.0021 17.9 10.6 0.0021 17.9 10.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67831.1 - 0.0034 17.7 11.7 0.0034 17.7 11.7 2.8 2 0 0 2 2 2 1 Ring finger domain DEAD PF00270.29 KEY67831.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KEY67831.1 - 0.022 13.7 0.0 0.076 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 KEY67831.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-Nse PF11789.8 KEY67831.1 - 0.17 11.7 4.2 0.53 10.2 4.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KEY67831.1 - 0.44 10.6 10.0 1.4 9.0 10.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 KEY67831.1 - 0.8 9.8 10.9 2.6 8.1 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Peptidase_M14 PF00246.24 KEY67832.1 - 2.7e-66 224.3 0.0 3.6e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KEY67832.1 - 0.0035 17.7 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Alpha-L-AF_C PF06964.12 KEY67833.1 - 9.3e-19 68.2 0.0 1.4e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain A2M_BRD PF07703.14 KEY67833.1 - 0.043 14.2 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin bait region domain Orn_Arg_deC_N PF02784.16 KEY67834.1 - 5.2e-87 291.3 0.0 7.4e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KEY67834.1 - 1.5e-18 66.8 0.0 2.6e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KEY67834.1 - 0.029 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Abhydrolase_3 PF07859.13 KEY67834.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold M16C_assoc PF08367.11 KEY67835.1 - 1.3e-83 280.0 0.0 3e-83 278.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KEY67835.1 - 6.2e-31 107.8 0.0 1.8e-19 70.5 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEY67835.1 - 5.4e-09 36.2 0.1 7.1e-08 32.5 0.0 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 KEY67835.1 - 0.015 15.4 0.8 0.063 13.4 0.1 2.3 2 0 0 2 2 2 0 UvrA interaction domain Taxilin PF09728.9 KEY67836.1 - 4e-89 298.8 59.4 4e-89 298.8 59.4 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 KEY67836.1 - 0.098 13.2 0.4 0.098 13.2 0.4 3.9 3 2 1 5 5 5 0 Domain of unknown function (DUF4810) Peptidase_M48_N PF16491.5 KEY67837.1 - 5.2e-64 215.5 5.5 5.2e-64 215.5 5.5 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KEY67837.1 - 4.8e-48 163.5 0.1 9.4e-48 162.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KEY67837.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 KEY67837.1 - 0.057 13.2 2.7 0.14 11.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Serpulina_VSP PF05540.11 KEY67837.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein Peptidase_M16_C PF05193.21 KEY67838.1 - 2.9e-18 66.5 0.0 5.1e-14 52.7 0.0 2.9 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEY67838.1 - 3e-09 37.0 0.2 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KEY67838.1 - 0.0087 15.2 0.4 0.35 9.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16C associated RQC PF09382.10 KEY67838.1 - 0.19 11.6 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 RQC domain Zw10 PF06248.13 KEY67839.1 - 2.4e-10 39.6 3.9 0.00033 19.4 0.0 2.7 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Dynactin_p22 PF07426.11 KEY67839.1 - 0.32 10.9 4.2 2.3 8.1 0.0 3.8 5 0 0 5 5 5 0 Dynactin subunit p22 PI-PLC-X PF00388.19 KEY67841.1 - 2e-59 199.4 0.0 3.5e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEY67841.1 - 9e-44 148.5 0.0 2.4e-43 147.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KEY67841.1 - 1.6e-07 31.6 0.0 4.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KEY67841.1 - 0.046 14.2 0.1 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.6 KEY67841.1 - 0.082 12.8 0.0 0.59 10.0 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair PH_12 PF16457.5 KEY67841.1 - 1.5 9.4 5.6 0.25 11.9 0.7 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DHHC PF01529.20 KEY67842.1 - 6e-39 133.2 6.6 1.1e-38 132.4 6.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4064 PF13273.6 KEY67842.1 - 0.06 13.6 0.9 0.094 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Yip1 PF04893.17 KEY67842.1 - 0.24 11.1 8.3 0.13 12.0 2.3 2.2 2 0 0 2 2 2 0 Yip1 domain zf-C2H2_4 PF13894.6 KEY67843.1 - 2.7e-07 30.8 12.7 0.038 14.8 0.1 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY67843.1 - 1.7e-06 28.1 0.1 0.015 15.6 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KEY67843.1 - 2.1e-06 27.9 9.9 0.0028 18.0 0.0 5.3 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-met PF12874.7 KEY67843.1 - 0.0001 22.5 1.8 0.14 12.6 0.1 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KEY67843.1 - 0.0061 16.8 3.5 0.014 15.6 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc ribbon Spt46 PF17734.1 KEY67843.1 - 0.034 13.9 3.6 2.8 7.7 0.1 2.8 2 1 1 3 3 3 0 Spermatogenesis-associated protein 46 zf-C2H2_2 PF12756.7 KEY67843.1 - 0.051 13.9 8.5 0.9 9.9 0.0 4.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KEY67843.1 - 0.17 11.9 8.3 0.53 10.4 1.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon AKNA PF12443.8 KEY67843.1 - 0.24 12.1 0.1 0.24 12.1 0.1 2.5 3 0 0 3 3 3 0 AT-hook-containing transcription factor zf-C2H2_6 PF13912.6 KEY67843.1 - 0.4 10.7 13.6 0.91 9.6 0.1 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KEY67843.1 - 0.68 10.1 3.8 0.39 10.9 0.7 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-UBR PF02207.20 KEY67843.1 - 0.72 10.1 7.7 0.37 11.0 4.0 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Zn-ribbon_8 PF09723.10 KEY67843.1 - 1.3 9.2 10.5 15 5.8 0.1 4.3 3 1 1 4 4 4 0 Zinc ribbon domain zf-Di19 PF05605.12 KEY67843.1 - 2.4 8.5 9.2 2.7 8.4 0.0 3.2 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Tau95 PF09734.9 KEY67844.1 - 2.1e-39 135.5 0.2 4.5e-39 134.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KEY67844.1 - 2.6e-35 121.4 0.0 4.2e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain B56 PF01603.20 KEY67845.1 - 1.3e-192 640.4 2.5 1.5e-192 640.2 2.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KEY67845.1 - 5.8e-05 23.1 1.4 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF737 PF05300.11 KEY67845.1 - 0.049 14.0 0.9 0.16 12.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) CTD_bind PF04818.13 KEY67846.1 - 5.8e-12 46.3 0.2 1.3e-11 45.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 KEY67847.1 - 1.3e-24 85.6 0.8 1.9e-24 85.2 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Exo_endo_phos PF03372.23 KEY67848.1 - 4.3e-09 36.2 0.2 9.4e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CRAL_TRIO PF00650.20 KEY67849.1 - 5.6e-36 123.7 0.0 7.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY67849.1 - 6.7e-15 55.0 0.1 1.5e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Apc13p PF05839.11 KEY67850.1 - 7e-27 93.5 0.0 7.8e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 KEY67851.1 - 4.7e-43 146.4 0.0 5.5e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCS1_N PF08740.11 KEY67852.1 - 1.9e-41 142.1 1.9 1.9e-41 142.1 1.9 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KEY67852.1 - 4.6e-17 62.7 0.0 2.2e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.14 KEY67852.1 - 0.0042 15.5 3.5 0.0059 15.0 3.5 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 KEY67852.1 - 0.0086 14.7 12.4 0.013 14.1 12.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RuvB_N PF05496.12 KEY67852.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KEY67852.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KEY67852.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEY67852.1 - 0.13 12.7 0.3 0.29 11.5 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF4692 PF15763.5 KEY67852.1 - 0.56 10.7 3.4 1.1 9.7 2.7 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) AAA_11 PF13086.6 KEY67852.1 - 6.4 6.5 12.4 1.7e+02 1.8 12.4 2.3 1 1 0 1 1 1 0 AAA domain TIP120 PF08623.10 KEY67853.1 - 3.4e-71 238.4 3.9 2.4e-67 225.9 0.0 4.6 3 1 1 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KEY67853.1 - 1.3e-16 60.8 19.0 0.0048 17.2 0.6 9.3 6 2 2 9 9 8 5 HEAT repeats HEAT PF02985.22 KEY67853.1 - 8.5e-15 53.6 23.1 0.4 11.1 0.2 14.1 16 0 0 16 16 15 3 HEAT repeat RTP1_C1 PF10363.9 KEY67853.1 - 9.7e-08 32.2 12.0 0.14 12.3 0.1 7.4 8 1 0 8 8 7 3 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 KEY67853.1 - 2.6e-07 30.5 2.7 1.7 8.6 0.0 6.5 5 2 1 6 6 6 1 UME (NUC010) domain Cnd1 PF12717.7 KEY67853.1 - 1.4e-06 28.4 16.2 0.046 13.8 0.6 6.8 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEY67853.1 - 8.6e-06 26.3 2.2 1.1 9.9 0.0 6.9 8 2 1 9 9 7 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KEY67853.1 - 2.2e-05 23.7 6.4 4 6.5 0.0 6.9 6 1 1 7 7 7 1 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 KEY67853.1 - 0.0004 20.1 10.5 0.98 8.9 0.2 5.0 5 1 0 5 5 4 2 Dos2-interacting transcription regulator of RNA-Pol-II VHS PF00790.19 KEY67853.1 - 0.0074 16.1 0.0 7 6.5 0.0 3.4 2 0 0 2 2 2 1 VHS domain Cnd3 PF12719.7 KEY67853.1 - 0.012 14.8 4.4 8.4 5.5 0.0 5.6 7 1 0 7 7 7 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KEY67853.1 - 0.051 14.1 22.3 30 5.2 0.0 11.4 10 2 4 14 14 13 0 HEAT-like repeat CLASP_N PF12348.8 KEY67853.1 - 0.13 11.8 5.3 1.3 8.5 0.0 4.8 6 1 2 8 8 7 0 CLASP N terminal SPOB_a PF14689.6 KEY67853.1 - 0.3 10.8 1.1 0.88 9.3 1.1 1.8 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain MMS19_C PF12460.8 KEY67853.1 - 0.51 9.4 19.0 0.6 9.1 0.3 5.7 6 1 0 7 7 7 0 RNAPII transcription regulator C-terminal DUF3453 PF11935.8 KEY67853.1 - 0.67 9.5 3.4 9.6 5.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3453) DUF3361 PF11841.8 KEY67853.1 - 0.69 9.8 16.3 23 4.9 0.1 6.5 4 2 0 5 5 5 0 Domain of unknown function (DUF3361) FANCI_S2 PF14676.6 KEY67853.1 - 0.72 10.2 3.3 3.8 7.8 0.0 3.8 4 0 0 4 4 3 0 FANCI solenoid 2 YL1 PF05764.13 KEY67853.1 - 1.7 8.7 7.3 3.4 7.7 7.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein RasGEF_N_2 PF14663.6 KEY67853.1 - 2.6 8.5 5.3 48 4.4 0.0 5.0 5 0 0 5 5 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pes-10 PF07149.11 KEY67853.1 - 3.5 6.6 11.3 1.9 7.4 4.3 2.8 3 0 0 3 3 3 0 Pes-10 CENP-B_dimeris PF09026.10 KEY67853.1 - 7.4 7.0 15.8 21 5.6 15.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pec_lyase_C PF00544.19 KEY67854.1 - 1.8e-41 142.0 0.8 1.8e-41 142.0 0.8 1.9 2 0 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 KEY67854.1 - 2.7e-05 24.1 3.5 0.0001 22.2 3.5 1.8 1 1 0 1 1 1 1 Right handed beta helix region PhoLip_ATPase_C PF16212.5 KEY67855.1 - 2.8e-72 243.5 19.3 2.8e-72 243.5 19.3 1.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEY67855.1 - 2.1e-22 78.6 0.1 7.1e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KEY67855.1 - 4.4e-13 49.1 0.0 4.2e-12 46.0 0.0 2.4 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEY67855.1 - 3.8e-12 47.0 0.2 1e-05 25.9 0.1 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEY67855.1 - 1.5e-09 37.6 0.0 1.1e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEY67855.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY67855.1 - 0.0082 16.6 0.3 5.6 7.3 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 KEY67856.1 - 3.2e-20 71.7 2.7 7e-20 70.6 2.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEY67856.1 - 0.026 14.4 0.3 0.067 13.1 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain FAM199X PF15814.5 KEY67856.1 - 5.9 5.9 5.3 9 5.2 5.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Adaptin_binding PF10199.9 KEY67858.1 - 1.1e-13 51.8 1.4 2.4e-13 50.8 1.4 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF5549 PF17703.1 KEY67858.1 - 0.0089 15.7 1.1 0.013 15.1 0.1 1.9 2 1 0 2 2 2 1 Family of unknown function (DUF5549) NdhL PF10716.9 KEY67859.1 - 0.1 12.6 2.3 0.2 11.6 2.3 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit F-box PF00646.33 KEY67860.1 - 0.00031 20.6 0.3 0.00073 19.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KEY67860.1 - 0.0027 17.6 0.2 0.0055 16.6 0.2 1.5 1 0 0 1 1 1 1 F-box CPSase_C PF18302.1 KEY67860.1 - 0.9 10.2 2.9 3.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Carbamoyl phosphate synthetase C-terminal domain ABC_membrane PF00664.23 KEY67861.1 - 2.4e-54 184.8 26.6 2.4e-34 119.2 7.6 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY67861.1 - 1.2e-51 174.8 0.0 1.5e-30 106.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY67861.1 - 2.1e-09 37.1 0.3 0.011 15.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEY67861.1 - 5.7e-08 33.5 0.5 0.0012 19.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KEY67861.1 - 4.6e-05 22.6 0.0 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KEY67861.1 - 6.1e-05 23.1 0.0 0.024 14.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY67861.1 - 0.00011 22.2 0.3 0.56 10.1 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KEY67861.1 - 0.00013 21.9 0.6 2.5 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEY67861.1 - 0.00016 22.1 0.0 0.46 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY67861.1 - 0.00046 19.9 0.8 0.9 9.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ResIII PF04851.15 KEY67861.1 - 0.0015 18.6 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KEY67861.1 - 0.002 17.5 0.4 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 KEY67861.1 - 0.0026 17.5 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KEY67861.1 - 0.0037 16.9 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY67861.1 - 0.0062 16.3 1.2 2.7 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KEY67861.1 - 0.007 16.6 0.4 8.7 6.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KEY67861.1 - 0.0072 16.8 0.1 11 6.5 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEY67861.1 - 0.019 14.5 0.1 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KEY67861.1 - 0.019 14.2 0.5 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain DUF87 PF01935.17 KEY67861.1 - 0.035 14.2 4.2 0.13 12.3 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 KEY67861.1 - 0.042 13.6 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KEY67861.1 - 0.054 14.0 0.0 7.7 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KEY67861.1 - 0.061 12.6 0.1 2.8 7.2 0.0 3.0 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain DEAD PF00270.29 KEY67861.1 - 0.086 12.6 0.0 6.4 6.5 0.0 3.1 3 1 0 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.16 KEY67861.1 - 0.093 12.2 0.2 11 5.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 KEY67861.1 - 0.11 11.8 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KEY67861.1 - 0.14 11.9 1.4 0.64 9.7 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 KEY67861.1 - 0.15 11.8 1.5 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KEY67861.1 - 0.16 12.4 0.0 40 4.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KEY67861.1 - 0.17 11.8 0.2 17 5.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 KEY67861.1 - 0.28 10.0 3.0 8.8 5.1 0.4 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KEY67861.1 - 0.5 9.9 1.8 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SecY PF00344.20 KEY67862.1 - 1.8e-71 240.9 7.3 2.3e-71 240.5 7.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KEY67862.1 - 3.1e-16 58.9 0.2 9.5e-16 57.4 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 KEY67862.1 - 0.96 9.6 3.3 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) IPPT PF01715.17 KEY67863.1 - 7.2e-60 202.6 0.3 9.8e-60 202.2 0.3 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KEY67863.1 - 0.00017 21.1 0.1 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 KEY67863.1 - 0.00028 21.0 0.2 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEY67863.1 - 0.0068 16.9 0.2 0.032 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain CTU2 PF10288.9 KEY67863.1 - 0.04 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 AAA_16 PF13191.6 KEY67863.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY67863.1 - 0.081 13.2 0.1 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY67863.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KEY67863.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.7 KEY67863.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Hpr_kinase_C PF07475.12 KEY67863.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_28 PF13521.6 KEY67863.1 - 0.18 12.0 0.6 0.62 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.8 KEY67863.1 - 0.18 12.1 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RNA_helicase PF00910.22 KEY67863.1 - 0.22 11.9 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.18 KEY67864.1 - 1.9e-16 59.9 0.1 3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sdh_cyt PF01127.22 KEY67864.1 - 4.8e-13 49.2 3.1 1e-12 48.1 3.1 1.5 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Zn_clus PF00172.18 KEY67864.1 - 1.2e-08 34.9 9.4 2e-08 34.2 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAF6_C PF07571.13 KEY67865.1 - 3.8e-27 94.4 0.1 7.4e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KEY67865.1 - 2.1e-22 79.0 0.2 3.7e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KEY67865.1 - 7.2e-05 23.2 0.1 0.00012 22.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KEY67865.1 - 0.045 13.8 0.0 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KEY67865.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DJ-1_PfpI PF01965.24 KEY67866.1 - 6.6e-16 58.6 0.0 2.1e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KEY67866.1 - 2.6e-10 40.3 0.0 9.7e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KEY67866.1 - 0.027 14.1 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal domain found in long catalases GATase_3 PF07685.14 KEY67866.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ADH_N PF08240.12 KEY67867.1 - 1.6e-23 82.6 6.0 2.6e-23 82.0 6.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY67867.1 - 2.4e-18 66.3 0.0 5.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY67867.1 - 2.7e-05 23.6 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY67867.1 - 0.00056 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 KEY67867.1 - 0.0058 17.3 0.0 1.6 9.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.18 KEY67867.1 - 0.29 11.0 0.6 0.85 9.5 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEY67867.1 - 0.56 9.5 2.4 0.43 9.9 0.5 1.7 2 0 0 2 2 2 0 ThiF family Opi1 PF08618.10 KEY67868.1 - 3.7e-19 69.3 21.9 3.8e-16 59.4 11.8 3.4 2 1 1 3 3 3 2 Transcription factor Opi1 MIP-T3_C PF17749.1 KEY67868.1 - 0.065 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Mur_ligase_M PF08245.12 KEY67869.1 - 2.2e-05 24.6 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEY67869.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Adap_comp_sub PF00928.21 KEY67870.1 - 2.8e-90 302.3 0.0 4.8e-90 301.5 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEY67870.1 - 2.5e-08 33.9 0.2 4.2e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SET PF00856.28 KEY67872.1 - 2e-17 64.1 0.0 4.4e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KEY67872.1 - 5.5e-06 27.1 0.0 1.6e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding UvdE PF03851.14 KEY67873.1 - 3e-113 377.6 0.0 4.2e-113 377.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE AMMECR1 PF01871.17 KEY67875.1 - 4.4e-45 153.3 0.0 5.6e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Ras PF00071.22 KEY67876.1 - 1.9e-39 134.9 0.0 2.5e-25 89.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEY67876.1 - 1.9e-11 44.2 0.0 4.3e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEY67876.1 - 0.0013 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KEY67876.1 - 0.0023 17.4 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family PRK PF00485.18 KEY67876.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pyridoxal_deC PF00282.19 KEY67877.1 - 3.3e-75 253.2 0.0 1.1e-73 248.1 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEY67877.1 - 5.5e-05 22.6 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KEY67877.1 - 0.00012 21.2 0.0 0.00028 20.0 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V Penicillinase_R PF03965.16 KEY67877.1 - 0.068 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor PUF PF00806.19 KEY67879.1 - 1.6e-12 46.3 0.0 0.27 11.0 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat CTI PF06934.11 KEY67879.1 - 0.13 10.7 0.2 0.19 10.2 0.2 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Oxysterol_BP PF01237.18 KEY67881.1 - 4.2e-50 170.7 0.0 7.8e-48 163.2 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Imm27 PF15590.6 KEY67881.1 - 0.19 11.6 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 27 Glyco_hydro_7 PF00840.20 KEY67882.1 - 1.3e-188 627.2 10.0 1.6e-188 626.9 10.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KEY67882.1 - 3.2e-10 39.8 16.7 3.2e-10 39.8 16.7 4.9 4 1 1 5 5 5 1 Fungal cellulose binding domain MAM33 PF02330.16 KEY67883.1 - 4.8e-73 245.6 1.5 7e-73 245.1 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 KEY67884.1 - 3.5e-44 150.2 0.4 4.2e-44 149.9 0.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Methyltr_RsmF_N PF17125.5 KEY67884.1 - 0.02 15.4 0.1 1 9.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF XPG_I PF00867.18 KEY67885.1 - 1e-23 83.5 0.0 2.8e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KEY67885.1 - 5.4e-08 33.2 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KEY67885.1 - 0.00026 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KEY67885.1 - 0.034 14.7 0.0 0.097 13.3 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TRAPPC9-Trs120 PF08626.11 KEY67885.1 - 0.048 11.0 0.1 0.084 10.2 0.1 1.3 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_8 PF13181.6 KEY67885.1 - 0.18 12.1 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat IBR PF01485.21 KEY67886.1 - 1.7e-21 76.2 43.0 1.6e-11 44.3 4.2 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KEY67886.1 - 0.00027 20.8 5.9 0.00027 20.8 5.9 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67886.1 - 0.0021 18.3 7.4 0.0021 18.3 7.4 4.2 2 1 1 3 3 3 1 Ring finger domain UN_NPL4 PF11543.8 KEY67886.1 - 0.035 14.6 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Redoxin PF08534.10 KEY67887.1 - 9.9e-26 90.2 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEY67887.1 - 5e-05 23.2 0.0 6.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PQQ_2 PF13360.6 KEY67887.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain Na_Ca_ex PF01699.24 KEY67888.1 - 1.1e-26 93.6 22.6 1.1e-14 54.7 10.3 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RasGAP PF00616.19 KEY67889.1 - 3.7e-57 193.4 0.4 1.3e-56 191.6 0.0 2.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KEY67889.1 - 7.8e-30 103.8 3.4 7.8e-30 103.8 3.4 2.6 3 0 0 3 3 3 1 RasGAP C-terminus APG6_N PF17675.1 KEY67889.1 - 1 9.9 5.1 12 6.5 1.0 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CorA PF01544.18 KEY67890.1 - 1.4e-12 47.5 0.2 3e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.13 KEY67890.1 - 0.006 16.7 0.7 0.81 9.8 0.2 3.0 3 0 0 3 3 3 1 DivIVA protein ASF1_hist_chap PF04729.13 KEY67891.1 - 6e-72 240.6 0.0 8.2e-72 240.2 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FliW PF02623.15 KEY67891.1 - 0.051 13.5 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 FliW protein Suf PF05843.14 KEY67892.1 - 2.2e-84 283.9 0.9 7.6e-81 272.3 0.0 3.8 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KEY67892.1 - 0.0088 16.8 0.1 0.32 11.9 0.0 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 KEY67892.1 - 0.088 12.8 0.3 0.36 10.8 0.3 2.0 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat PAXIP1_C PF15364.6 KEY67892.1 - 0.46 10.8 4.3 1.5 9.2 0.2 2.9 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein HrpJ PF07201.11 KEY67892.1 - 0.47 10.8 2.1 28 5.0 0.0 3.7 5 0 0 5 5 5 0 HrpJ-like domain Piwi PF02171.17 KEY67893.1 - 2.1e-76 257.0 0.0 3.1e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEY67893.1 - 5.7e-14 52.9 0.2 1.4e-13 51.6 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KEY67893.1 - 6.9e-12 45.4 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KEY67893.1 - 8.1e-12 44.6 0.0 2.9e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KEY67893.1 - 5.3e-06 26.7 0.1 2.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KEY67893.1 - 5.7e-05 23.3 0.1 0.00023 21.4 0.1 2.0 1 0 0 1 1 1 1 Mid domain of argonaute Lgl_C PF08596.10 KEY67894.1 - 3.2e-118 394.8 0.0 5.3e-118 394.1 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KEY67894.1 - 1.8e-07 31.7 1.0 0.014 16.2 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY67894.1 - 0.15 12.3 0.0 13 6.1 0.0 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pyridoxal_deC PF00282.19 KEY67895.1 - 5.2e-59 199.8 0.0 6.8e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KEY67895.1 - 4.2e-09 36.1 0.0 6.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEY67895.1 - 3.6e-08 33.0 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KEY67895.1 - 1.1e-07 31.2 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 KEY67895.1 - 0.00079 18.2 0.0 0.0017 17.1 0.0 1.5 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF868 PF05910.12 KEY67895.1 - 0.012 15.2 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) DUF3802 PF12290.8 KEY67895.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) SHMT PF00464.19 KEY67896.1 - 2.7e-208 691.4 0.0 3.1e-208 691.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KEY67896.1 - 0.00013 21.2 0.0 0.00029 20.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEY67896.1 - 0.00043 19.3 0.1 0.00063 18.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEY67896.1 - 0.027 13.7 0.0 0.055 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEY67896.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Baculo_DNA_bind PF04786.12 KEY67896.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein RINT1_TIP1 PF04437.13 KEY67897.1 - 1.3e-176 588.4 0.0 2.7e-176 587.3 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DHR10 PF18595.1 KEY67897.1 - 0.018 15.1 1.8 0.018 15.1 1.8 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain AAA_lid_9 PF17871.1 KEY67897.1 - 0.36 10.8 2.2 1.8 8.5 0.3 3.0 4 0 0 4 4 4 0 AAA lid domain DUF4164 PF13747.6 KEY67897.1 - 0.63 10.4 10.3 0.93 9.8 6.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4472 PF14739.6 KEY67897.1 - 2.1 9.1 6.4 0.57 10.9 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) FliJ PF02050.16 KEY67897.1 - 5.1 7.3 10.3 1.5 9.0 6.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Mito_carr PF00153.27 KEY67898.1 - 4.6e-56 186.7 2.5 7e-20 70.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 KEY67899.1 - 3.5e-49 166.5 0.7 3.5e-49 166.5 0.7 2.0 2 0 0 2 2 2 1 Sec34-like family SKA2 PF16740.5 KEY67899.1 - 0.14 11.9 2.7 3 7.7 0.0 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 RCC1 PF00415.18 KEY67900.1 - 3.3e-27 94.9 5.7 2.2e-05 25.0 0.0 8.3 7 1 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEY67900.1 - 9.5e-11 41.2 0.7 6.6e-08 32.2 0.0 6.7 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.27 KEY67901.1 - 1e-46 159.4 0.0 1.6e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEY67901.1 - 0.00025 21.2 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KEY67901.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KEY67901.1 - 0.0059 16.6 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Miff PF05644.11 KEY67902.1 - 0.036 13.7 0.7 0.092 12.4 0.7 1.6 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Prefoldin PF02996.17 KEY67904.1 - 3.4e-36 123.8 0.0 5.1e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KEY67904.1 - 0.00028 20.8 0.1 0.008 16.1 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit Filament PF00038.21 KEY67904.1 - 0.0062 16.2 0.8 0.34 10.4 0.1 2.0 2 0 0 2 2 2 2 Intermediate filament protein FlaC_arch PF05377.11 KEY67904.1 - 0.039 14.3 0.6 2.6 8.5 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) VanZ PF04892.12 KEY67905.1 - 1.7e-06 28.7 3.4 2.5e-06 28.2 3.4 1.2 1 0 0 1 1 1 1 VanZ like family DUF2070 PF09843.9 KEY67905.1 - 0.15 10.3 1.9 0.18 10.0 1.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 KEY67905.1 - 0.38 8.9 3.4 0.45 8.7 3.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 KEY67905.1 - 8.2 6.1 6.9 85 2.7 6.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Bromodomain PF00439.25 KEY67906.1 - 8.8e-19 67.4 0.7 8.8e-19 67.4 0.7 2.2 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KEY67906.1 - 1.1e-09 38.1 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated DUF4611 PF15387.6 KEY67906.1 - 1.1 9.6 20.3 1.4 9.1 1.7 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4611) Ferric_reduct PF01794.19 KEY67907.1 - 4.3e-18 65.6 10.7 7.3e-18 64.9 9.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY67907.1 - 2.7e-12 47.1 0.0 4.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KEY67907.1 - 9.3e-05 23.0 0.0 0.79 10.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KEY67907.1 - 0.00028 20.9 0.0 0.0017 18.4 0.0 2.3 2 1 0 2 2 2 1 FAD-binding domain RRM_1 PF00076.22 KEY67908.1 - 5e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY67908.1 - 0.00023 20.8 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 KEY67909.1 - 1e-13 51.3 5.5 1.7e-13 50.5 5.5 1.3 1 0 0 1 1 1 1 RF-1 domain UPF0300 PF08594.10 KEY67909.1 - 0.038 13.3 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Pkinase PF00069.25 KEY67910.1 - 4e-70 236.2 0.0 5e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67910.1 - 1.9e-28 99.5 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY67910.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEY67910.1 - 0.00012 21.0 0.0 0.00026 19.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEY67910.1 - 0.00036 20.5 0.1 0.00054 20.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY67910.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_DrpA PF18255.1 KEY67910.1 - 0.018 15.3 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain PAP2_3 PF14378.6 KEY67911.1 - 4.1e-24 85.3 11.4 4.1e-24 85.3 11.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KEY67911.1 - 4.3e-11 42.7 3.5 4.3e-11 42.7 3.5 2.2 2 0 0 2 2 2 1 PAP2 superfamily RNA_polI_A34 PF08208.11 KEY67912.1 - 5.8e-28 98.4 43.5 5.8e-28 98.4 43.5 6.4 2 2 2 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 KEY67913.1 - 1.1e-32 113.4 0.0 1.7e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 KEY67913.1 - 0.024 15.2 0.0 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEY67913.1 - 0.12 12.5 0.1 0.69 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain NIF3 PF01784.18 KEY67915.1 - 7.3e-58 196.1 0.0 9e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) LptC PF06835.13 KEY67915.1 - 0.044 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related baeRF_family3 PF18845.1 KEY67915.1 - 0.053 13.8 0.2 0.14 12.5 0.1 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Vps51 PF08700.11 KEY67916.1 - 1.4e-28 98.8 0.1 2.4e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KEY67916.1 - 1.5e-05 23.9 0.1 1.9e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 KEY67916.1 - 0.0011 19.2 0.4 0.0038 17.4 0.4 1.8 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Vps53_N PF04100.12 KEY67916.1 - 0.23 10.4 0.1 0.36 9.7 0.0 1.4 2 0 0 2 2 2 0 Vps53-like, N-terminal RMI1_N PF08585.12 KEY67917.1 - 9.9e-57 192.2 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Gly_reductase PF09338.11 KEY67917.1 - 0.1 10.9 0.1 0.15 10.4 0.1 1.3 1 1 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits TPR_2 PF07719.17 KEY67918.1 - 2e-43 143.0 36.8 0.0019 18.2 0.1 17.4 16 0 0 16 16 16 10 Tetratricopeptide repeat TPR_16 PF13432.6 KEY67918.1 - 9.3e-42 141.4 41.1 1.6e-09 38.3 0.3 14.1 11 5 6 17 17 14 10 Tetratricopeptide repeat TPR_14 PF13428.6 KEY67918.1 - 4.2e-35 117.4 33.4 3.6e-05 24.2 0.0 16.3 12 5 5 17 17 16 8 Tetratricopeptide repeat TPR_1 PF00515.28 KEY67918.1 - 2.3e-34 115.8 37.1 0.00029 20.5 0.0 16.4 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_19 PF14559.6 KEY67918.1 - 3.9e-33 113.8 21.6 5.1e-05 23.7 0.0 9.8 9 2 1 11 11 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 KEY67918.1 - 1.2e-30 103.1 28.4 0.01 16.0 0.1 15.1 17 0 0 17 17 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 KEY67918.1 - 1.2e-28 97.4 5.5 1 9.9 0.0 16.9 19 0 0 19 19 17 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEY67918.1 - 1.4e-21 76.5 33.8 0.013 15.8 0.0 13.2 13 2 1 14 14 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEY67918.1 - 2.8e-21 74.9 22.8 0.0022 17.7 0.1 10.6 10 1 1 11 11 11 5 TPR repeat TPR_7 PF13176.6 KEY67918.1 - 4.3e-21 73.3 19.6 0.0028 17.6 0.0 14.4 15 1 0 15 15 13 5 Tetratricopeptide repeat TPR_6 PF13174.6 KEY67918.1 - 1.1e-14 54.0 26.5 0.00089 19.7 0.0 14.7 19 0 0 19 19 12 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY67918.1 - 3e-09 36.9 22.0 0.031 14.4 0.4 9.4 11 1 1 12 12 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY67918.1 - 3.3e-09 36.8 14.5 0.029 14.6 0.7 7.7 6 2 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 KEY67918.1 - 2e-07 31.1 0.0 5.9e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY67918.1 - 9.7e-06 25.2 7.9 0.042 13.2 0.0 6.2 5 1 0 6 6 6 1 MalT-like TPR region DUF4919 PF16266.5 KEY67918.1 - 6e-05 23.1 1.4 0.006 16.6 0.3 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) HemY_N PF07219.13 KEY67918.1 - 0.00032 20.8 3.9 5.7 7.2 0.0 6.0 4 1 1 5 5 5 1 HemY protein N-terminus TPR_20 PF14561.6 KEY67918.1 - 0.00047 20.4 16.1 1.3 9.4 0.1 7.2 6 1 1 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.10 KEY67918.1 - 0.0021 17.1 0.8 5.3 5.9 0.0 4.7 5 1 1 6 6 6 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KEY67918.1 - 0.02 15.0 10.8 3.1 7.9 0.0 7.3 9 0 0 9 9 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KEY67918.1 - 0.035 14.0 0.2 0.035 14.0 0.2 8.5 13 0 0 13 13 8 0 Tetratricopeptide repeat EXS PF03124.14 KEY67918.1 - 0.054 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 EXS family DUF2225 PF09986.9 KEY67918.1 - 0.062 13.0 2.4 16 5.1 0.0 3.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) ClpS PF02617.17 KEY67918.1 - 0.078 12.8 0.0 0.88 9.4 0.0 2.7 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS DUF4105 PF13387.6 KEY67918.1 - 0.082 12.5 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) EST1_DNA_bind PF10373.9 KEY67918.1 - 0.097 12.1 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain PPTA PF01239.22 KEY67918.1 - 0.1 12.4 0.8 49 3.9 0.0 3.9 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat ANAPC5 PF12862.7 KEY67918.1 - 0.32 11.1 13.1 6.5 6.9 0.5 6.1 6 2 0 6 6 5 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 KEY67918.1 - 0.81 9.8 4.9 2.4 8.2 0.2 4.0 5 0 0 5 5 3 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 KEY67918.1 - 3.1 8.7 21.1 4 8.3 0.3 8.7 10 0 0 10 10 7 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 KEY67919.1 - 5.9e-23 81.2 0.0 2.3e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KEY67919.1 - 4.4e-12 46.0 2.3 1.2e-08 34.8 0.9 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KEY67919.1 - 0.0051 16.2 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 KEY67919.1 - 0.0057 16.3 0.1 0.0098 15.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 MamL-1 PF09596.10 KEY67919.1 - 0.19 12.0 0.4 0.39 11.0 0.4 1.5 1 0 0 1 1 1 0 MamL-1 domain Pkinase PF00069.25 KEY67920.1 - 3.9e-62 210.0 0.0 5.6e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY67920.1 - 2.5e-47 161.3 0.0 3.9e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY67920.1 - 1.2e-08 34.6 0.0 7.8e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEY67920.1 - 0.0027 17.1 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEY67920.1 - 0.01 14.7 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEY67920.1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.20 KEY67923.1 - 2.5e-174 580.5 0.0 3e-174 580.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SARAF PF06682.12 KEY67923.1 - 0.11 12.2 1.5 0.49 10.0 0.0 2.4 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Glyco_hydro_127 PF07944.12 KEY67923.1 - 0.13 10.7 0.0 9.2 4.6 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Fig1 PF12351.8 KEY67924.1 - 6.5e-57 192.5 2.6 6.5e-57 192.5 2.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KEY67924.1 - 3.3e-07 30.1 9.9 3.4e-07 30.1 9.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KEY67924.1 - 0.0075 15.4 10.7 0.013 14.6 10.3 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Thi4 PF01946.17 KEY67925.1 - 8.2e-115 382.0 0.0 1e-114 381.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KEY67925.1 - 7.3e-07 29.1 1.1 1.2e-06 28.3 0.9 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY67925.1 - 4.3e-06 26.9 0.3 1.3e-05 25.3 0.3 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY67925.1 - 6e-05 22.4 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY67925.1 - 0.00014 21.0 0.3 0.00014 21.0 0.3 1.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY67925.1 - 0.0021 18.0 1.6 0.0032 17.4 0.1 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEY67925.1 - 0.0026 16.9 2.3 0.0059 15.7 0.6 2.2 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KEY67925.1 - 0.0041 16.5 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY67925.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY67925.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KEY67925.1 - 0.035 12.9 0.2 0.051 12.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KEY67925.1 - 0.057 12.1 0.3 0.08 11.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KEY67925.1 - 0.13 11.3 0.2 0.49 9.4 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A BolA PF01722.18 KEY67926.1 - 1.5e-21 76.4 0.0 4e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.20 KEY67927.1 - 4.9e-136 454.4 3.8 6.9e-136 453.9 3.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEY67927.1 - 3.9e-65 218.8 1.5 2.5e-61 206.5 0.3 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY67927.1 - 2.2e-17 63.2 0.1 2.2e-07 31.2 0.0 5.1 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KEY67927.1 - 2.9e-11 42.6 5.0 0.022 15.0 0.0 6.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KEY67927.1 - 6.3e-05 23.4 0.0 0.64 10.6 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat UNC45-central PF11701.8 KEY67927.1 - 0.0016 18.4 1.3 0.33 10.9 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KEY67927.1 - 0.028 14.0 0.1 1.5 8.3 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal TFIID-18kDa PF02269.16 KEY67927.1 - 0.032 14.2 0.6 21 5.3 0.1 3.2 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit Arm PF00514.23 KEY67927.1 - 0.036 14.1 1.2 6.2 7.0 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DNA_ligase_A_M PF01068.21 KEY67928.1 - 4.9e-50 170.0 0.1 1.7e-47 161.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEY67928.1 - 8e-35 120.7 0.0 1.5e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KEY67928.1 - 1.3e-19 70.6 0.0 8.6e-19 68.0 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KEY67928.1 - 7.7e-05 23.1 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KEY67928.1 - 0.084 12.7 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain CSN8_PSD8_EIF3K PF10075.9 KEY67929.1 - 2.9e-35 121.3 0.0 3.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 KEY67930.1 - 6.5e-48 163.1 0.0 6.8e-47 159.8 0.0 2.1 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DSBA PF01323.20 KEY67930.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Cpn60_TCP1 PF00118.24 KEY67931.1 - 2.5e-163 544.2 0.5 2.8e-163 544.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KEY67931.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4470 PF14737.6 KEY67932.1 - 3.8e-23 81.5 0.1 1.1e-22 80.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEY67932.1 - 1.2e-11 44.5 17.2 2.7e-11 43.4 17.2 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KEY67932.1 - 0.68 10.3 13.1 1.7 9.0 13.1 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2 PF00096.26 KEY67933.1 - 2.5e-10 40.2 19.0 0.00042 20.6 7.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY67933.1 - 2.1e-07 31.0 12.0 0.0039 17.6 3.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY67933.1 - 6.8e-05 23.4 17.6 0.21 12.5 6.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEY67933.1 - 0.35 10.9 7.6 8.7 6.5 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger AT_hook PF02178.19 KEY67933.1 - 1.2 9.2 5.2 4.6 7.5 5.2 2.1 1 0 0 1 1 1 0 AT hook motif CBS PF00571.28 KEY67934.1 - 2.6e-33 114.2 9.5 1e-08 35.4 0.0 5.9 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KEY67934.1 - 9.2e-09 35.1 0.1 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 PB1 domain PBP1_TM PF14812.6 KEY67934.1 - 4.6 7.7 8.7 0.11 12.8 1.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S2 PF00318.20 KEY67935.1 - 4.8e-65 218.8 0.2 2e-63 213.5 0.2 2.6 1 1 0 1 1 1 1 Ribosomal protein S2 zf-H2C2 PF09337.10 KEY67936.1 - 2.1e-15 56.7 1.2 4.1e-15 55.7 1.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KEY67936.1 - 8.1e-12 45.1 0.1 2.3e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KEY67936.1 - 2.7e-05 24.4 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KEY67936.1 - 0.00081 19.6 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEY67936.1 - 0.012 16.3 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY67936.1 - 0.22 11.5 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.24 KEY67938.1 - 7.4e-156 519.6 6.8 8.4e-156 519.4 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KEY67938.1 - 0.077 13.5 0.1 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 KEY67938.1 - 0.48 10.9 2.3 1.4 9.4 2.4 2.1 1 1 0 1 1 1 0 Cell division protein FtsA Glyco_hydro_20 PF00728.22 KEY67939.1 - 7.1e-25 88.1 2.8 4.8e-18 65.7 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KEY67939.1 - 9e-06 26.5 0.0 2.8e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Acetyltransf_10 PF13673.7 KEY67940.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY67940.1 - 2.2e-05 24.8 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY67940.1 - 9e-05 22.7 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CorA PF01544.18 KEY67940.1 - 0.0048 16.3 0.1 0.0072 15.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KEY67941.1 - 7.1e-28 97.5 80.7 1.6e-22 79.9 41.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY67941.1 - 0.00056 18.9 41.4 0.0028 16.6 7.2 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KEY67941.1 - 0.26 9.7 15.0 0.15 10.5 3.2 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector YoqO PF14037.6 KEY67941.1 - 4.5 7.8 7.0 8.9 6.9 0.5 3.1 3 0 0 3 3 3 0 YoqO-like protein AIM24 PF01987.17 KEY67942.1 - 4e-52 177.0 0.0 4.9e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Kinesin PF00225.23 KEY67943.1 - 4.3e-81 272.4 0.0 5.7e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEY67943.1 - 1.1e-21 77.3 0.0 2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding PBP1_TM PF14812.6 KEY67943.1 - 0.0019 18.5 0.3 0.0046 17.3 0.3 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0184 PF03670.13 KEY67943.1 - 0.0032 17.8 0.4 4.6 7.7 0.1 2.8 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0184) HHH_3 PF12836.7 KEY67943.1 - 0.079 13.2 0.5 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Proteasome_A_N PF10584.9 KEY67945.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Peptidase_S8 PF00082.22 KEY67946.1 - 1.3e-41 142.9 0.1 1.8e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Zip PF02535.22 KEY67947.1 - 5.2e-33 114.7 43.4 5.8e-14 52.1 4.9 4.1 3 1 1 4 4 4 3 ZIP Zinc transporter MutS_V PF00488.21 KEY67948.1 - 2.3e-81 272.3 0.1 3.6e-81 271.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEY67948.1 - 1.2e-36 126.8 0.2 5.6e-36 124.6 0.1 2.3 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KEY67948.1 - 7.9e-23 81.3 0.9 6.9e-21 75.0 0.1 2.9 2 1 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KEY67948.1 - 1.1e-17 64.3 0.0 5.7e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KEY67948.1 - 8.3e-13 48.5 2.0 2.5e-12 47.0 0.6 2.6 3 0 0 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 KEY67948.1 - 0.032 13.8 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Tim17 PF02466.19 KEY67949.1 - 1.7e-05 25.2 7.8 0.00012 22.4 5.4 2.1 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family tRNA_m1G_MT PF01746.21 KEY67950.1 - 6.7e-25 87.9 0.0 1.2e-19 70.8 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DNA_primase_S PF01896.19 KEY67951.1 - 2.4e-62 210.1 0.7 2.4e-62 210.1 0.7 1.7 2 0 0 2 2 2 1 DNA primase small subunit MIP PF00230.20 KEY67952.1 - 5.6e-41 140.7 4.5 7.5e-41 140.3 4.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein MMR_HSR1 PF01926.23 KEY67953.1 - 7.3e-11 42.2 1.9 1.5e-10 41.1 0.4 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEY67953.1 - 1.1e-05 24.8 0.2 2.3e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KEY67953.1 - 9.8e-05 21.8 0.2 9.8e-05 21.8 0.2 1.6 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 KEY67953.1 - 0.00046 19.8 0.1 0.0011 18.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEY67953.1 - 0.00059 19.9 5.2 0.5 10.4 0.2 3.1 2 1 1 3 3 3 2 Dynamin family NB-ARC PF00931.22 KEY67953.1 - 0.002 17.4 0.0 0.0048 16.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain DLIC PF05783.11 KEY67953.1 - 0.0033 16.3 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KEY67953.1 - 0.0051 17.3 0.6 0.012 16.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KEY67953.1 - 0.015 15.2 1.0 0.015 15.2 1.0 2.3 2 1 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 KEY67953.1 - 0.019 14.6 0.1 0.061 13.0 0.1 1.9 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Spc7 PF08317.11 KEY67953.1 - 0.039 12.8 4.9 0.059 12.2 4.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_22 PF13401.6 KEY67953.1 - 0.041 14.2 0.2 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KEY67953.1 - 0.043 12.9 0.6 0.25 10.3 0.2 2.1 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 KEY67953.1 - 0.11 12.7 0.6 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF4460 PF14687.6 KEY67953.1 - 0.12 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) VirE PF05272.11 KEY67953.1 - 0.16 11.7 1.7 4.4 7.0 0.0 2.7 3 1 0 3 3 3 0 Virulence-associated protein E ATP_bind_1 PF03029.17 KEY67953.1 - 0.29 10.9 3.8 0.15 11.8 0.6 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KEY67953.1 - 0.32 10.9 3.5 1.1 9.1 0.5 2.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KEY67953.1 - 3 7.9 7.4 0.75 9.8 1.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain HSF_DNA-bind PF00447.17 KEY67955.1 - 5.9e-29 100.5 0.6 1.1e-28 99.7 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KEY67955.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain SDH_alpha PF03313.15 KEY67955.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain YabA PF06156.13 KEY67955.1 - 0.2 12.3 2.8 0.42 11.3 2.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA W2 PF02020.18 KEY67957.1 - 1.7e-22 79.3 1.4 3.6e-22 78.3 1.4 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KEY67957.1 - 3.2e-09 36.1 13.6 6.7e-06 25.6 6.3 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KEY67957.1 - 0.00019 19.7 0.2 0.00028 19.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KEY67957.1 - 0.0037 17.0 15.7 0.33 10.7 0.6 3.2 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 KEY67957.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEY67957.1 - 0.0091 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KEY67957.1 - 0.043 12.7 0.2 0.072 12.0 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase HAD_SAK_1 PF10307.9 KEY67958.1 - 1.4e-75 253.6 0.0 2e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF167 PF02594.16 KEY67959.1 - 9.6e-22 76.9 0.5 1.5e-21 76.3 0.2 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 CP2 PF04516.15 KEY67961.1 - 1.2e-82 276.7 0.0 1.7e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KEY67961.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Tektin family MFS_1 PF07690.16 KEY67963.1 - 3.5e-31 108.4 38.3 4.7e-31 108.0 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY67963.1 - 0.055 12.3 18.3 0.012 14.5 10.8 2.7 2 1 0 2 2 2 0 Sugar (and other) transporter eIF2A PF08662.11 KEY67964.1 - 1.3e-78 263.4 0.0 5e-78 261.4 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KEY67964.1 - 0.089 11.3 0.0 0.24 9.9 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain RPAP1_C PF08620.10 KEY67965.1 - 5.7e-27 93.6 0.1 1.2e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KEY67965.1 - 1.8e-19 69.2 4.3 3e-19 68.5 4.3 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF438 PF04282.13 KEY67965.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) Dimerisation PF08100.11 KEY67965.1 - 0.16 12.0 0.1 0.57 10.2 0.1 1.9 2 0 0 2 2 2 0 Dimerisation domain HUN PF08729.10 KEY67966.1 - 9.8e-07 28.7 0.1 2.8e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain VHS PF00790.19 KEY67967.1 - 6.5e-45 152.4 0.0 3.2e-44 150.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KEY67967.1 - 1.4e-18 67.2 0.0 3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KEY67967.1 - 1.5e-18 66.9 0.1 1.5e-18 66.9 0.1 2.3 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KEY67967.1 - 5.5e-07 29.1 0.1 1.8e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain DUF3829 PF12889.7 KEY67967.1 - 0.23 10.9 4.0 0.37 10.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Ribo_biogen_C PF04034.13 KEY67968.1 - 1.1e-49 167.3 0.0 1.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KEY67968.1 - 1.4e-12 47.2 0.6 3.8e-12 45.8 0.6 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI GTP_EFTU PF00009.27 KEY67969.1 - 3.2e-32 111.7 4.8 9e-31 106.9 4.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KEY67969.1 - 1.3e-27 95.9 1.1 4.3e-27 94.3 1.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KEY67969.1 - 2.6e-09 37.2 0.2 6.3e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KEY67969.1 - 7.6e-07 28.9 0.1 1.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KEY67969.1 - 2.7e-05 24.1 1.9 0.00079 19.4 0.2 2.7 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 KEY67969.1 - 0.00018 21.9 2.5 0.19 12.1 0.2 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 PduV-EutP PF10662.9 KEY67969.1 - 0.00019 21.2 0.1 0.00061 19.6 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KEY67969.1 - 0.00052 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KEY67969.1 - 0.0014 18.1 0.1 0.0037 16.7 0.1 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEY67969.1 - 0.009 16.2 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3854 PF12965.7 KEY67969.1 - 0.04 13.9 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DraK_HK_N PF18092.1 KEY67969.1 - 0.057 13.8 1.2 0.23 11.9 1.2 2.0 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain NAD2 PF18782.1 KEY67970.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 KEY67970.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 GPP34 PF05719.11 KEY67971.1 - 6.8e-68 228.7 0.3 8.7e-68 228.4 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.12 KEY67972.1 - 2.1e-49 168.1 41.7 2.1e-49 168.1 41.7 4.2 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KEY67972.1 - 3.1e-17 62.9 1.4 3.1e-17 62.9 1.4 7.8 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 Lentiviral_Tat PF02998.14 KEY67972.1 - 3.6 7.7 9.4 0.5 10.4 4.4 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein PP28 PF10252.9 KEY67973.1 - 4.4e-29 100.7 18.2 4.4e-29 100.7 18.2 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DUF3246 PF11596.8 KEY67973.1 - 0.88 8.9 9.7 1.3 8.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PI3K_1B_p101 PF10486.9 KEY67973.1 - 7.6 4.2 15.3 10 3.7 15.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CoA_trans PF01144.23 KEY67975.1 - 1.2e-99 332.0 1.6 8.6e-62 208.4 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D4 PF17405.2 KEY67976.1 - 1.3e-60 204.4 0.2 2.3e-60 203.6 0.2 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KEY67976.1 - 1.3e-58 197.3 0.0 2.8e-57 193.0 0.1 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KEY67976.1 - 6.6e-47 159.1 0.0 6.1e-44 149.4 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KEY67976.1 - 1.2e-46 158.5 0.3 2.4e-46 157.5 0.1 1.7 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KEY67976.1 - 8.9e-45 152.6 0.0 2.1e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KEY67976.1 - 1.5e-35 122.4 0.0 9.4e-35 119.8 0.0 2.2 2 0 0 2 2 2 1 Nrap protein domain 6 I-set PF07679.16 KEY67977.1 - 3.5e-05 23.8 0.1 1.7 8.8 0.1 5.2 5 1 0 5 5 5 2 Immunoglobulin I-set domain DUF1918 PF08940.11 KEY67977.1 - 0.00082 19.0 0.5 0.3 10.7 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.21 KEY67978.1 - 4e-55 186.8 0.0 6.9e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cucumo_2B PF03263.13 KEY67978.1 - 0.1 13.1 0.4 0.23 11.9 0.1 1.8 2 0 0 2 2 2 0 Cucumovirus protein 2B DUF3408 PF11888.8 KEY67978.1 - 0.88 9.7 6.3 0.072 13.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Transglut_core2 PF13369.6 KEY67979.1 - 3.1e-23 82.1 0.0 5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KEY67979.1 - 8.3e-10 39.1 0.0 2.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KEY67979.1 - 9.3e-09 35.1 0.9 2e-08 34.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY67979.1 - 0.00025 20.8 0.2 0.00066 19.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KEY67979.1 - 0.036 14.6 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A AAA_12 PF13087.6 KEY67979.1 - 0.15 11.7 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 KEY67980.1 - 2.2e-26 91.8 2.5 2.2e-26 91.8 2.5 17.1 5 3 9 14 14 14 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KEY67980.1 - 1.3e-22 80.2 1.6 1.3e-22 80.2 1.6 5.8 6 2 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KEY67980.1 - 7.3e-06 25.1 211.5 0.0092 14.9 21.1 10.3 1 1 10 11 11 11 7 Spc7 kinetochore protein ADIP PF11559.8 KEY67980.1 - 0.00037 20.6 13.5 0.00037 20.6 13.5 13.8 3 3 11 14 14 14 2 Afadin- and alpha -actinin-Binding MAD PF05557.13 KEY67980.1 - 0.00077 18.0 46.1 0.00077 18.0 46.1 6.2 1 1 5 6 6 6 2 Mitotic checkpoint protein AAA_13 PF13166.6 KEY67980.1 - 0.0013 17.5 25.9 0.0013 17.5 25.9 5.8 1 1 3 5 5 5 3 AAA domain MscS_porin PF12795.7 KEY67980.1 - 0.0023 17.5 29.7 0.0023 17.5 29.7 8.2 1 1 7 8 8 8 2 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 KEY67980.1 - 0.0034 17.4 7.4 0.0034 17.4 7.4 16.0 6 5 10 17 17 17 1 TolA binding protein trimerisation ABC_tran_CTD PF16326.5 KEY67980.1 - 0.0065 16.7 14.5 0.0065 16.7 14.5 17.0 6 4 10 18 18 18 7 ABC transporter C-terminal domain Peptidase_C14 PF00656.22 KEY67981.1 - 1.7e-63 214.9 0.0 2.3e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain SKG6 PF08693.10 KEY67984.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.8 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Myc_target_1 PF15179.6 KEY67984.1 - 0.068 13.1 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 SNF2_N PF00176.23 KEY67985.1 - 1.3e-69 234.5 0.0 1.9e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KEY67985.1 - 6.3e-25 86.9 0.0 1.2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KEY67985.1 - 8.6e-16 58.3 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY67985.1 - 6.3e-08 32.8 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KEY67985.1 - 0.0011 18.8 9.5 0.0022 17.8 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY67985.1 - 0.0036 17.1 8.3 0.0066 16.3 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY67985.1 - 0.0042 16.9 7.0 0.0094 15.8 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY67985.1 - 0.015 15.6 10.7 0.039 14.3 10.7 1.8 1 0 0 1 1 1 0 Ring finger domain UBA_4 PF14555.6 KEY67985.1 - 0.13 12.1 0.2 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain zf-RING_UBOX PF13445.6 KEY67985.1 - 0.13 12.3 9.4 0.28 11.2 9.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger AAA_22 PF13401.6 KEY67985.1 - 0.15 12.3 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain zf-RING_5 PF14634.6 KEY67985.1 - 0.15 12.0 8.0 0.63 10.0 8.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain SQS_PSY PF00494.19 KEY67986.1 - 5.4e-57 193.3 0.0 7.5e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.17 KEY67986.1 - 3.4e-24 84.9 0.0 6.2e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.15 KEY67987.1 - 3.3e-34 117.9 4.8 4.5e-34 117.5 3.6 1.8 2 0 0 2 2 2 1 Cullin binding PTCB-BRCT PF12738.7 KEY67988.1 - 2.8e-45 152.1 0.6 4.3e-18 65.0 0.1 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KEY67988.1 - 1.5e-43 147.0 0.3 1.1e-11 44.9 0.1 4.5 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEY67988.1 - 2.5e-18 66.3 0.0 0.00032 21.1 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KEY67988.1 - 1.6e-10 41.1 0.4 0.00034 20.9 0.0 3.7 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KEY67988.1 - 0.0006 19.7 0.0 0.38 10.7 0.0 3.5 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KEY67988.1 - 0.014 15.5 0.1 0.82 9.8 0.0 3.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 KEY67989.1 - 1.7e-11 43.6 36.2 1.4e-07 30.8 22.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily NifU_N PF01592.16 KEY67989.1 - 0.18 12.0 0.6 13 5.9 0.0 2.2 2 0 0 2 2 2 0 NifU-like N terminal domain DUF3716 PF12511.8 KEY67990.1 - 1.1e-07 31.7 8.6 2e-07 30.9 8.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cluap1 PF10234.9 KEY67990.1 - 0.13 11.6 6.0 0.27 10.6 6.0 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMPIT PF07851.13 KEY67990.1 - 0.33 10.2 2.4 0.62 9.3 2.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KEY67990.1 - 0.49 9.7 6.9 2.1 7.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KEY67990.1 - 0.57 10.4 4.4 2.1 8.6 4.4 2.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 MRPL52 PF18699.1 KEY67990.1 - 0.69 10.1 4.1 2.6 8.3 4.1 2.0 1 0 0 1 1 1 0 Mitoribosomal protein mL52 IFP_35_N PF07334.13 KEY67990.1 - 3.4 7.8 5.4 6.6 6.9 1.2 2.8 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus APG6_N PF17675.1 KEY67990.1 - 9.5 6.7 18.2 0.53 10.8 11.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Chs7 PF12271.8 KEY67991.1 - 3.4e-122 407.3 13.9 3.9e-122 407.1 13.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KEY67991.1 - 0.0051 17.0 1.7 0.0051 17.0 1.7 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3382) SIR2 PF02146.17 KEY67992.1 - 2.2e-33 115.7 0.0 3.6e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Sir2 family UvrD-helicase PF00580.21 KEY67992.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Acetyltransf_1 PF00583.25 KEY67993.1 - 2.4e-08 34.2 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY67993.1 - 7.2e-05 23.1 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY67993.1 - 0.0034 17.3 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KEY67993.1 - 0.0054 16.9 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_13 PF13880.6 KEY67993.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KEY67993.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PIG-L PF02585.17 KEY67994.1 - 1.2e-27 97.1 0.1 1.9e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF202 PF02656.15 KEY67996.1 - 0.051 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF3552 PF12072.8 KEY67996.1 - 0.75 9.2 7.7 0.11 11.9 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ADH_N_2 PF16884.5 KEY67997.1 - 1.6e-19 69.8 0.0 2.9e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY67997.1 - 2.1e-17 63.3 0.0 3.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY67997.1 - 1.8e-09 38.8 0.0 5.9e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.16 KEY67997.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Nha1_C PF08619.10 KEY67998.1 - 4e-113 379.1 23.2 4.8e-113 378.8 23.2 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KEY67998.1 - 2.1e-73 247.3 21.3 2.6e-73 247.0 21.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.6 KEY67998.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain Colicin_E5 PF12106.8 KEY67998.1 - 0.094 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain YrhC PF14143.6 KEY67998.1 - 0.23 11.6 6.5 0.085 13.0 0.5 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF4190 PF13828.6 KEY67998.1 - 3.4 7.5 5.4 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) CENP-B_dimeris PF09026.10 KEY67999.1 - 1.5 9.3 5.7 2.5 8.5 5.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SH3_1 PF00018.28 KEY68000.1 - 3.2e-09 36.2 0.1 4.9e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY68000.1 - 6e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY68000.1 - 2.9e-06 26.9 0.0 6.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.14 KEY68000.1 - 0.1 12.2 6.6 0.15 11.7 6.6 1.2 1 0 0 1 1 1 0 YhhN family DASH_Spc19 PF08287.11 KEY68001.1 - 7.4e-41 139.7 7.5 6.6e-26 91.1 2.3 2.6 1 1 1 2 2 2 2 Spc19 Thioredoxin_6 PF13848.6 KEY68001.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain COG5 PF10392.9 KEY68001.1 - 0.37 11.0 2.9 1.9 8.7 0.3 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 GPI-anchored PF10342.9 KEY68002.1 - 0.057 14.2 0.4 6.3 7.6 0.1 2.2 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GRDP-like PF07173.12 KEY68003.1 - 1.2e-14 55.2 0.6 4.9e-14 53.2 0.1 2.1 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like CxC7 PF18866.1 KEY68003.1 - 0.061 13.5 1.0 0.2 11.8 1.0 2.0 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases PCI PF01399.27 KEY68004.1 - 3.7e-22 78.8 0.0 1.1e-21 77.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KEY68004.1 - 2.2e-16 59.6 1.9 5.2e-16 58.4 1.9 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 KEY68005.1 - 3.6e-59 200.0 0.0 4.4e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KEY68005.1 - 5.1e-05 24.0 2.5 0.0011 19.6 2.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY68005.1 - 0.0036 16.6 0.2 0.027 13.8 0.0 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KEY68005.1 - 0.0075 15.8 0.2 0.83 9.1 0.3 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase PE-PPE PF08237.11 KEY68005.1 - 0.021 14.4 0.0 0.054 13.0 0.0 1.6 1 1 1 2 2 2 0 PE-PPE domain Abhydrolase_2 PF02230.16 KEY68005.1 - 0.43 10.4 2.3 82 2.9 1.9 3.1 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase ATP-synt_J PF04911.12 KEY68006.1 - 6e-26 89.8 1.6 6.8e-26 89.6 1.6 1.1 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.13 KEY68007.1 - 2.5e-41 140.0 2.5 7.4e-30 103.2 0.1 2.9 3 0 0 3 3 3 2 NIPSNAP Rogdi_lz PF10259.9 KEY68008.1 - 9.6e-92 307.2 0.0 1.1e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 KEY68009.1 - 1.4e-24 86.6 0.0 2.4e-24 85.8 0.0 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KEY68009.1 - 1.9e-08 34.0 0.0 3.5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Alba DUF3237 PF11578.8 KEY68010.1 - 3e-14 53.1 0.0 8e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) OST-HTH PF12872.7 KEY68010.1 - 0.038 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain FMO-like PF00743.19 KEY68012.1 - 6.4e-36 123.9 0.0 7.2e-29 100.6 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY68012.1 - 6e-12 45.4 0.0 3.2e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY68012.1 - 7.9e-08 31.8 0.0 4.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY68012.1 - 1.5e-07 30.9 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY68012.1 - 3.4e-05 23.9 1.0 1 9.3 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KEY68012.1 - 0.079 12.2 0.1 26 3.9 0.0 2.8 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Myb_DNA-binding PF00249.31 KEY68013.1 - 1.5e-17 63.5 4.5 8.3e-09 35.5 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY68013.1 - 1.8e-15 56.9 7.1 3.7e-11 43.1 0.2 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KEY68013.1 - 0.026 14.9 3.1 0.15 12.5 3.1 2.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 KEY68014.1 - 2.1e-09 38.0 0.0 5.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KEY68014.1 - 5.8e-07 29.7 0.1 8.7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KEY68014.1 - 0.02 14.1 0.1 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KEY68014.1 - 0.049 13.2 0.1 0.44 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain PRORP PF16953.5 KEY68014.1 - 0.053 13.0 0.2 0.083 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein-only RNase P AAA_7 PF12775.7 KEY68014.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KEY68014.1 - 0.088 13.1 0.4 0.3 11.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY68014.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 KEY68014.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Fungal_trans_2 PF11951.8 KEY68016.1 - 4.7e-32 111.3 2.1 3.6e-22 78.7 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68016.1 - 1.3e-08 34.9 11.8 2.3e-08 34.0 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KEY68016.1 - 0.084 12.8 4.7 0.23 11.4 4.7 1.8 1 0 0 1 1 1 0 AT hook motif Ank_2 PF12796.7 KEY68018.1 - 1.3e-55 185.9 2.9 9.8e-09 35.7 0.0 8.6 5 3 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68018.1 - 4.4e-42 141.9 10.6 6.8e-06 26.5 0.0 10.6 7 3 2 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68018.1 - 3.5e-31 103.8 16.3 0.0091 16.4 0.0 16.6 17 0 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 KEY68018.1 - 7.8e-19 67.5 16.5 0.0032 17.7 0.0 11.6 9 4 4 13 13 13 5 Ankyrin repeats (many copies) Ank PF00023.30 KEY68018.1 - 4.3e-14 52.2 28.8 0.42 11.2 0.0 13.7 15 1 1 16 16 16 6 Ankyrin repeat Cutinase PF01083.22 KEY68018.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase MFS_1 PF07690.16 KEY68019.1 - 7.2e-34 117.3 26.5 7.2e-34 117.3 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SKG6 PF08693.10 KEY68020.1 - 4.1e-05 22.9 0.0 0.00011 21.5 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KEY68020.1 - 0.00022 20.2 1.1 0.00022 20.2 1.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein MLANA PF14991.6 KEY68020.1 - 0.062 13.6 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A DUF347 PF03988.12 KEY68020.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) PRCC PF10253.9 KEY68020.1 - 1.9 9.2 8.9 6.5 7.5 8.9 1.9 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting NAD_binding_6 PF08030.12 KEY68021.1 - 7.3e-33 113.9 0.0 1.3e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY68021.1 - 6.4e-19 68.1 0.1 2.4e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KEY68021.1 - 6.3e-18 65.1 12.4 6.3e-18 65.1 12.4 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEY68021.1 - 0.18 12.4 0.0 0.64 10.7 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain UQ_con PF00179.26 KEY68022.1 - 4.2e-52 175.5 0.0 4.8e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY68022.1 - 0.0042 16.8 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEY68022.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KEY68022.1 - 0.044 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 KEY68023.1 - 1.3e-25 90.2 0.8 2.6e-25 89.3 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEY68023.1 - 3e-22 79.5 0.1 5e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEY68023.1 - 5.3e-16 58.6 0.0 9.3e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEY68023.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIP5K PF01504.18 KEY68025.1 - 1.8e-100 335.7 0.0 3.6e-100 334.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.17 KEY68026.1 - 2.7e-20 72.4 2.1 3.6e-20 72.0 2.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SYS1 PF09801.9 KEY68027.1 - 2.3e-47 160.7 4.9 2.7e-47 160.5 4.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Lactamase_B_6 PF16661.5 KEY68028.1 - 7e-65 218.1 0.0 1.1e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KEY68028.1 - 1.3e-50 171.9 0.1 1.3e-50 171.9 0.1 2.5 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KEY68028.1 - 2.2e-17 63.3 0.0 2.9e-16 59.7 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KEY68028.1 - 3e-12 46.3 0.0 7.7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KEY68028.1 - 0.063 12.8 0.0 0.16 11.4 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Gti1_Pac2 PF09729.9 KEY68029.1 - 5.2e-43 147.2 2.0 8.2e-36 123.8 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family ABM PF03992.16 KEY68030.1 - 0.00023 21.2 0.8 0.76 9.9 0.0 2.9 2 1 1 3 3 3 2 Antibiotic biosynthesis monooxygenase Ribosomal_L38e PF01781.18 KEY68031.1 - 9.8e-34 115.3 5.8 1.1e-33 115.1 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 KEY68032.1 - 1.1e-05 25.7 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein NMO PF03060.15 KEY68034.1 - 2.4e-49 168.5 0.1 3.5e-49 168.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEY68034.1 - 1.3e-08 34.2 0.3 1.3e-07 31.0 0.3 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY68034.1 - 0.00087 18.4 1.2 0.0015 17.7 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DEAD PF00270.29 KEY68035.1 - 3.8e-48 163.6 0.1 8.9e-48 162.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68035.1 - 2.8e-25 88.8 0.1 2.9e-24 85.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEY68035.1 - 4.9e-18 65.1 0.1 8.7e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEY68035.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEY68035.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Sigma70_ner PF04546.13 KEY68035.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 KEY68035.1 - 3.3 7.4 12.3 5.4 6.7 12.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KEY68035.1 - 9.8 4.1 9.1 16 3.4 9.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_4 PF01565.23 KEY68036.1 - 3e-16 59.4 0.2 5.6e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_31 PF01055.26 KEY68038.1 - 1.3e-155 518.9 2.1 1.6e-155 518.6 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KEY68038.1 - 4.5e-37 126.8 0.0 8.1e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KEY68038.1 - 1.6e-11 44.3 1.5 1.6e-11 44.3 1.5 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Zn_clus PF00172.18 KEY68039.1 - 3.9e-16 58.9 24.4 1.1e-08 35.0 6.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY68039.1 - 1.2e-14 54.0 1.2 1.9e-14 53.3 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.20 KEY68041.1 - 2.2e-56 190.5 0.0 5e-56 189.4 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KEY68041.1 - 1.2e-43 148.5 0.3 2.3e-43 147.6 0.3 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KEY68041.1 - 7.4e-19 67.6 0.7 1.6e-18 66.5 0.7 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KEY68041.1 - 1.6e-12 47.6 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEY68041.1 - 2.2e-06 28.0 0.1 4.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KEY68041.1 - 4.4e-05 23.4 0.2 0.0001 22.2 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain F-box PF00646.33 KEY68042.1 - 0.0039 17.0 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY68042.1 - 0.0054 16.6 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Hap4_Hap_bind PF10297.9 KEY68043.1 - 5.3e-08 32.7 6.9 5.3e-08 32.7 6.9 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KEY68043.1 - 0.0083 16.2 14.5 0.015 15.3 12.1 2.6 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY68043.1 - 4.9 7.3 14.0 20 5.4 13.3 2.4 1 1 1 2 2 2 0 Basic region leucine zipper HMMR_N PF15905.5 KEY68043.1 - 6 6.2 18.2 0.011 15.3 6.2 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal COG2 PF06148.11 KEY68044.1 - 1.5e-26 93.0 1.3 2.2e-26 92.5 1.3 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KEY68044.1 - 0.0022 18.0 0.5 0.0072 16.4 0.1 2.0 1 1 1 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 KEY68044.1 - 0.0031 16.4 4.2 0.0046 15.9 4.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein COG5 PF10392.9 KEY68044.1 - 0.0043 17.2 0.6 0.011 16.0 0.6 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Zw10 PF06248.13 KEY68044.1 - 0.025 13.2 0.5 0.035 12.7 0.5 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DLP_helical PF18709.1 KEY68044.1 - 0.062 12.5 2.1 0.14 11.4 0.9 1.9 2 0 0 2 2 2 0 Dynamin-like helical domain Dor1 PF04124.12 KEY68044.1 - 0.064 11.9 2.3 0.092 11.4 2.3 1.2 1 0 0 1 1 1 0 Dor1-like family Atg14 PF10186.9 KEY68044.1 - 0.075 12.1 2.5 0.14 11.2 2.5 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec5 PF15469.6 KEY68044.1 - 0.077 12.8 0.9 0.098 12.4 0.2 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 BST2 PF16716.5 KEY68044.1 - 0.11 13.1 6.6 6 7.5 0.0 3.1 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 KEY68044.1 - 0.25 11.1 3.1 8.4 6.1 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MCD_N PF17408.2 KEY68044.1 - 0.32 11.2 3.4 0.66 10.1 0.7 2.6 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF1664 PF07889.12 KEY68044.1 - 0.42 10.6 1.8 0.85 9.7 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4611 PF15387.6 KEY68044.1 - 1.1 9.6 6.6 0.36 11.1 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TPR_MLP1_2 PF07926.12 KEY68044.1 - 1.9 8.6 7.7 15 5.7 3.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 KEY68044.1 - 7.9 6.9 8.0 15 6.0 5.2 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Ribosomal_L1 PF00687.21 KEY68045.1 - 1.7e-25 90.0 0.0 2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KEY68046.1 - 1.9e-103 345.7 0.0 2.5e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEY68046.1 - 5.2e-38 130.6 0.0 9.7e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KEY68046.1 - 0.047 13.0 0.2 0.13 11.6 0.1 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain SBF PF01758.16 KEY68047.1 - 3.9e-50 170.3 8.3 3.9e-50 170.3 8.3 1.8 3 0 0 3 3 3 1 Sodium Bile acid symporter family PsbI PF02532.14 KEY68047.1 - 1.1 9.3 5.6 0.9 9.5 1.8 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Phyto_Pns9_10 PF05878.11 KEY68048.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 EspB PF05802.11 KEY68048.1 - 0.037 14.0 0.6 0.059 13.4 0.6 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein TAFII28 PF04719.14 KEY68049.1 - 6e-33 112.8 0.0 1.2e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region NOA36 PF06524.12 KEY68049.1 - 0.28 10.4 2.6 0.37 10.1 2.6 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEY68049.1 - 0.65 10.4 4.9 1.4 9.3 4.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLU-1 PF08429.11 KEY68050.1 - 5.8e-113 377.5 12.6 1.4e-110 369.6 10.6 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KEY68050.1 - 2e-43 147.5 0.2 4.6e-43 146.3 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KEY68050.1 - 4.1e-21 75.4 0.0 1.1e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KEY68050.1 - 5.4e-15 55.1 2.0 1.1e-14 54.1 2.0 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KEY68050.1 - 1.3e-14 53.8 21.5 6e-10 38.9 3.9 4.0 4 0 0 4 4 4 2 PHD-finger zf-C5HC2 PF02928.16 KEY68050.1 - 7.4e-12 45.5 8.0 9.2e-12 45.2 6.2 2.3 2 0 0 2 2 2 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KEY68050.1 - 0.00045 19.9 5.4 0.017 14.8 0.2 2.9 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KEY68050.1 - 0.0014 18.2 0.5 0.0014 18.2 0.5 2.8 2 0 0 2 2 2 1 PHD-finger SPATA24 PF15175.6 KEY68050.1 - 3.4 7.5 6.7 1.9 8.3 0.3 3.2 3 1 1 4 4 4 0 Spermatogenesis-associated protein 24 PHD_4 PF16866.5 KEY68050.1 - 6.9 6.8 18.9 0.82 9.8 5.8 3.2 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.24 KEY68051.1 - 1.5e-12 47.6 0.0 3.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KEY68051.1 - 0.014 15.7 3.1 0.014 15.7 3.1 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain T5orf172 PF10544.9 KEY68051.1 - 0.033 14.7 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 T5orf172 domain DiS_P_DiS PF06750.13 KEY68051.1 - 0.077 13.1 0.3 1.6 8.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain zf-HC5HC2H_2 PF13832.6 KEY68051.1 - 0.31 11.2 8.1 0.068 13.3 4.5 1.7 2 1 0 2 2 2 0 PHD-zinc-finger like domain DUF3449 PF11931.8 KEY68052.1 - 7.3e-78 260.6 1.6 1e-77 260.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KEY68052.1 - 2.2e-26 92.2 1.0 2.2e-26 92.2 1.0 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KEY68052.1 - 2.3e-11 43.3 0.1 5.2e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KEY68052.1 - 7.8e-08 32.5 1.6 6.1e-06 26.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEY68052.1 - 2e-06 28.0 1.0 2e-06 28.0 1.0 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KEY68052.1 - 0.0018 18.5 1.0 0.027 14.8 0.3 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEY68052.1 - 0.015 16.1 1.0 3.1 8.9 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PRP9_N PF16958.5 KEY68052.1 - 0.06 13.4 0.3 0.06 13.4 0.3 3.4 4 1 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF4088 PF13317.6 KEY68052.1 - 0.18 11.4 1.2 0.36 10.4 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) zf-C2H2 PF00096.26 KEY68052.1 - 0.31 11.6 4.1 1.1 9.8 0.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-DBF PF07535.12 KEY68052.1 - 3.9 7.7 6.9 0.71 10.0 0.6 2.8 2 1 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 KEY68053.1 - 2.1e-42 144.9 0.2 3.4e-42 144.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68053.1 - 2.8e-33 114.6 0.0 1.1e-32 112.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KEY68053.1 - 0.00049 19.9 0.1 0.00076 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KEY68053.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KEY68053.1 - 0.002 18.5 0.1 0.015 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KEY68053.1 - 0.071 13.1 0.2 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KEY68053.1 - 0.082 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KEY68053.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KEY68053.1 - 0.17 12.1 0.9 0.84 9.9 0.9 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1g PF09334.11 KEY68055.1 - 7.2e-140 466.2 6.8 9.7e-139 462.4 6.8 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEY68055.1 - 1.7e-06 26.6 1.6 0.014 13.7 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEY68055.1 - 0.0021 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1688 PF07958.11 KEY68056.1 - 4.6e-173 575.8 0.0 1.1e-162 541.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1688) 60KD_IMP PF02096.20 KEY68057.1 - 6.3e-13 49.0 0.9 1.1e-12 48.2 0.9 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Coa1 PF08695.10 KEY68057.1 - 0.075 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 TOM13 PF08219.11 KEY68058.1 - 6.8e-37 125.3 0.0 9.1e-37 124.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 KEY68059.1 - 5.5e-24 84.5 0.0 1.1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KEY68059.1 - 4.6e-11 42.3 0.0 7.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KEY68059.1 - 8.9e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain BDHCT_assoc PF16204.5 KEY68059.1 - 0.00014 21.6 0.7 0.00025 20.8 0.7 1.3 1 0 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein TAP_C PF03943.13 KEY68059.1 - 0.096 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 TAP C-terminal domain Gtr1_RagA PF04670.12 KEY68060.1 - 8.1e-89 296.9 0.0 1.5e-88 296.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KEY68060.1 - 1.1e-06 28.4 0.1 7.1e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY68060.1 - 1.4e-06 28.5 0.3 1.3e-05 25.4 0.0 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY68060.1 - 1.9e-06 27.5 0.4 4.3e-05 23.0 0.2 2.7 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEY68060.1 - 0.00012 22.0 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KEY68060.1 - 0.00042 19.6 2.1 0.22 10.7 0.1 2.8 3 0 0 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KEY68060.1 - 0.00045 20.3 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KEY68060.1 - 0.004 16.9 1.6 0.039 13.7 0.1 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEY68060.1 - 0.0068 16.9 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KEY68060.1 - 0.013 15.0 0.1 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KEY68060.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KEY68060.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sugar_tr PF00083.24 KEY68063.1 - 3e-25 89.0 23.8 1.3e-18 67.1 7.4 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEY68063.1 - 4.4e-24 85.1 25.5 4.4e-24 85.1 25.5 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Pec_lyase_C PF00544.19 KEY68064.1 - 1.4e-34 119.5 7.4 2.4e-34 118.8 7.4 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY68064.1 - 3.9e-05 23.5 10.5 0.00032 20.6 10.5 2.2 1 1 0 1 1 1 1 Right handed beta helix region SWIM PF04434.17 KEY68064.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger Glyco_transf_21 PF13506.6 KEY68065.1 - 1.4e-14 53.9 0.2 1e-05 25.1 0.0 3.2 2 1 0 3 3 3 3 Glycosyl transferase family 21 tRNA_int_endo PF01974.17 KEY68066.1 - 5.2e-18 64.9 0.3 1.8e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KEY68066.1 - 9.9e-05 21.9 0.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain SQHop_cyclase_C PF13243.6 KEY68067.1 - 2.1e-49 168.3 0.1 1.5e-46 159.0 0.3 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KEY68067.1 - 8.2e-41 140.0 3.1 1.6e-34 119.3 0.6 3.4 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KEY68067.1 - 9.3e-29 98.9 10.1 3.7e-10 39.4 0.1 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KEY68067.1 - 0.034 13.2 0.0 0.4 9.7 0.0 2.6 2 1 1 3 3 3 0 A-macroglobulin TED domain Pec_lyase PF09492.10 KEY68067.1 - 0.079 12.3 0.3 0.76 9.0 0.1 2.7 3 0 0 3 3 3 0 Pectic acid lyase SGS PF05002.15 KEY68068.1 - 5.1e-29 100.2 1.4 1.4e-28 98.8 1.4 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KEY68068.1 - 5.1e-11 43.4 0.1 9.5e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KEY68068.1 - 1.9e-06 27.5 6.2 0.049 13.7 0.3 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY68068.1 - 2.3e-06 27.2 0.4 0.022 14.6 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY68068.1 - 5.3e-05 23.8 4.6 0.05 14.2 2.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY68068.1 - 0.0072 16.8 0.6 0.71 10.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY68068.1 - 0.023 15.3 0.7 2.9 8.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY68068.1 - 0.065 14.1 4.5 22 6.2 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68068.1 - 0.13 12.6 0.1 5.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TauD PF02668.16 KEY68069.1 - 3.7e-40 138.4 0.0 7e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KEY68069.1 - 3.1e-06 27.7 0.0 1e-05 26.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KEY68069.1 - 0.0099 15.0 0.0 0.033 13.3 0.0 1.7 2 0 0 2 2 2 1 CsiD TP6A_N PF04406.14 KEY68070.1 - 3.8e-22 78.0 1.1 1.2e-21 76.5 0.4 2.1 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DBD_HTH PF18430.1 KEY68070.1 - 0.013 15.2 1.2 0.04 13.7 0.1 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain Ank_2 PF12796.7 KEY68071.1 - 1.1e-19 70.8 2.8 4.2e-12 46.5 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY68071.1 - 7.8e-16 57.9 0.9 2.5e-10 40.4 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY68071.1 - 7.4e-15 55.1 0.4 2.6e-07 31.0 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY68071.1 - 1.3e-09 38.0 0.9 1.5e-05 25.2 0.9 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEY68071.1 - 1.2e-08 34.5 0.3 0.00014 22.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF1110 PF06533.12 KEY68071.1 - 0.026 14.5 1.4 0.93 9.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) Fungal_trans PF04082.18 KEY68072.1 - 1.3e-57 194.8 0.0 2.2e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY68072.1 - 2.3e-07 30.9 6.1 0.0099 16.3 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY68072.1 - 0.0022 18.6 5.7 1.4 9.9 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY68072.1 - 0.0045 17.3 4.1 0.014 15.9 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger double domain PIP5K PF01504.18 KEY68073.1 - 2.6e-45 154.8 0.0 1.1e-43 149.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.8 KEY68074.1 - 1.1e-232 773.7 0.0 1.2e-232 773.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) HPP PF04982.13 KEY68075.1 - 2.2e-39 134.4 6.3 3.6e-39 133.7 6.3 1.3 1 0 0 1 1 1 1 HPP family Homeodomain PF00046.29 KEY68076.1 - 0.096 12.5 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 0 Homeodomain Chromo PF00385.24 KEY68077.1 - 8.3e-08 32.0 0.2 8.3e-07 28.8 0.3 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Pam17 PF08566.10 KEY68078.1 - 7e-60 201.6 0.0 1.1e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 KEY68078.1 - 0.0008 18.6 0.4 0.0012 18.0 0.4 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ThiF PF00899.21 KEY68079.1 - 5.4e-30 104.5 0.0 7.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KEY68079.1 - 2.1e-12 47.5 0.0 3.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain GPS2_interact PF15784.5 KEY68079.1 - 0.078 13.4 0.1 0.21 12.1 0.1 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain PKcGMP_CC PF16808.5 KEY68079.1 - 0.1 12.4 2.5 0.25 11.2 2.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SLX9 PF15341.6 KEY68080.1 - 4.5e-36 124.1 7.8 5.8e-36 123.8 7.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 MCM3AP_GANP PF16769.5 KEY68080.1 - 0.054 11.8 1.3 0.065 11.5 1.3 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Peptidase_C48 PF02902.19 KEY68081.1 - 5.3e-19 68.9 0.0 1.4e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 KEY68081.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease Fez1 PF06818.15 KEY68082.1 - 6.4 7.2 6.9 0.29 11.6 0.5 1.9 2 0 0 2 2 2 0 Fez1 AIG2_2 PF13772.6 KEY68083.1 - 9.1e-06 26.0 0.1 0.00027 21.3 0.1 2.4 2 0 0 2 2 2 1 AIG2-like family DUF3267 PF11667.8 KEY68083.1 - 0.00065 20.0 1.7 0.0012 19.2 1.7 1.3 1 0 0 1 1 1 1 Putative zincin peptidase LptF_LptG PF03739.14 KEY68083.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG NAD_Gly3P_dh_N PF01210.23 KEY68084.1 - 7.7e-45 152.7 0.0 1.4e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KEY68084.1 - 5.3e-42 143.5 0.2 9e-42 142.7 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HABP4_PAI-RBP1 PF04774.15 KEY68084.1 - 0.14 13.0 0.1 0.28 12.1 0.1 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family COesterase PF00135.28 KEY68085.1 - 1.2e-91 308.2 0.0 1.8e-91 307.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY68085.1 - 0.00065 19.6 0.1 0.0025 17.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY68085.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY68086.1 - 3.5e-08 34.3 8.2 3.5e-08 34.3 8.2 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.14 KEY68086.1 - 4.3e-08 32.8 0.7 0.0018 17.7 0.6 2.3 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 KEY68086.1 - 0.00015 21.1 0.4 0.012 14.9 0.4 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY68086.1 - 0.0016 18.0 0.1 0.33 10.4 0.2 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEY68086.1 - 0.0037 16.9 2.1 0.65 9.6 1.3 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KEY68086.1 - 0.042 13.4 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 KEY68086.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) hDGE_amylase PF14701.6 KEY68087.1 - 5.6e-178 592.5 0.0 7.5e-178 592.1 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KEY68087.1 - 4.7e-120 401.0 0.5 6.5e-120 400.6 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KEY68087.1 - 2.4e-90 302.6 0.0 1.1e-89 300.4 0.0 2.1 3 0 0 3 3 3 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KEY68087.1 - 4.9e-30 103.5 0.0 1.1e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4834 PF16118.5 KEY68088.1 - 0.05 14.6 0.1 2.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) UPF0370 PF13980.6 KEY68088.1 - 0.087 12.9 4.1 0.11 12.6 3.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) TMEM154 PF15102.6 KEY68088.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4231 PF14015.6 KEY68088.1 - 0.17 12.4 0.2 0.35 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4381 PF14316.6 KEY68088.1 - 0.17 12.1 1.3 0.27 11.5 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RSN1_7TM PF02714.15 KEY68090.1 - 1.5e-74 250.8 25.4 2.4e-74 250.1 25.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY68090.1 - 3.8e-36 124.2 0.4 3.8e-36 124.2 0.4 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEY68090.1 - 9.3e-35 120.4 0.0 1.3e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter F-box-like PF12937.7 KEY68091.1 - 0.00051 19.9 0.2 0.0013 18.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like 2-Hacid_dh_C PF02826.19 KEY68092.1 - 5.8e-55 185.4 0.0 1.1e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY68092.1 - 3.1e-31 107.8 0.0 4.3e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEY68092.1 - 4.3e-06 27.0 0.0 2.9e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KEY68092.1 - 0.0016 18.5 0.3 0.0044 17.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY68092.1 - 0.0024 17.2 1.2 0.025 13.9 1.1 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KEY68092.1 - 0.0047 17.4 0.0 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 KEY68092.1 - 0.041 13.5 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 KEY68092.1 - 0.056 13.9 0.1 0.17 12.4 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain FMO-like PF00743.19 KEY68094.1 - 2.7e-15 55.8 0.0 5.7e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEY68094.1 - 1.1e-09 38.0 0.0 6.9e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY68094.1 - 7e-09 35.9 0.2 5.7e-08 32.9 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KEY68094.1 - 8.9e-09 34.9 0.1 4e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEY68094.1 - 2.5e-07 30.8 0.0 2.4e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY68094.1 - 5.4e-06 25.9 0.1 0.003 16.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY68094.1 - 0.00037 20.2 0.0 0.63 9.6 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEY68094.1 - 0.0047 16.2 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KEY68094.1 - 0.0058 17.2 0.4 3.3 8.3 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY68094.1 - 0.009 15.3 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KEY68094.1 - 0.012 14.3 0.1 0.021 13.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEY68094.1 - 0.04 13.1 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.6 KEY68095.1 - 1.9e-21 76.8 0.0 2.5e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY68095.1 - 0.034 13.6 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY68095.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Adhesin_P1_N PF18652.1 KEY68095.1 - 0.14 12.2 3.6 0.099 12.7 1.6 1.9 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain 4HBT PF03061.22 KEY68096.1 - 0.0025 18.1 0.0 0.0048 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily GTP1_OBG PF01018.22 KEY68096.1 - 0.071 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 GTP1/OBG C2 PF00168.30 KEY68097.1 - 7.1e-10 39.1 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain FKBP_C PF00254.28 KEY68098.1 - 3.1e-23 81.9 0.0 3.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.21 KEY68099.1 - 1.4e-112 374.9 0.0 1.7e-76 256.8 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KEY68099.1 - 3.3e-92 309.0 0.6 6.1e-92 308.1 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KEY68099.1 - 2.4e-32 110.9 0.1 5.3e-32 109.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KEY68099.1 - 5.6e-30 103.9 0.1 1.1e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KEY68099.1 - 3.1e-25 88.2 0.3 8.5e-25 86.7 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 KEY68100.1 - 3.2e-23 81.8 0.1 9.5e-23 80.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY68100.1 - 2.6e-14 53.0 0.0 5.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY68100.1 - 9.8e-08 32.3 0.1 0.02 15.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY68100.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY68100.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KEY68100.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sec1 PF00995.23 KEY68102.1 - 1.5e-115 387.7 0.0 1.7e-115 387.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 KEY68103.1 - 6.4e-06 26.0 0.1 1.6e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 G-patch domain HEXIM PF15313.6 KEY68103.1 - 0.14 12.3 1.2 0.25 11.5 1.2 1.4 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Zn_clus PF00172.18 KEY68104.1 - 1.7e-09 37.6 12.3 5.1e-09 36.1 12.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY68104.1 - 4.8e-09 35.6 0.5 1.8e-08 33.7 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Phage_prot_Gp6 PF05133.14 KEY68104.1 - 0.24 10.4 0.0 0.46 9.5 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Exo5 PF09810.9 KEY68105.1 - 8.1e-138 459.9 0.0 9.9e-138 459.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KEY68105.1 - 0.00099 19.1 0.0 2.6 7.9 0.1 3.0 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Glyco_hydro_7 PF00840.20 KEY68107.1 - 6.9e-147 489.7 0.1 8.4e-147 489.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DHO_dh PF01180.21 KEY68109.1 - 7.9e-66 222.3 0.0 1.1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KEY68109.1 - 6.8e-05 22.1 0.6 0.022 13.8 0.6 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 KEY68109.1 - 0.14 11.6 0.8 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 PcrB family Mg_trans_NIPA PF05653.14 KEY68110.1 - 8.8e-92 307.3 24.8 1.2e-91 306.9 24.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KEY68110.1 - 1.4e-06 28.6 7.9 1.4e-06 28.6 7.9 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF805 PF05656.14 KEY68110.1 - 1.8 9.0 17.4 4.1 7.9 6.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF5362 PF17319.2 KEY68110.1 - 3.2 7.7 9.4 0.29 11.0 0.3 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5362) U-box PF04564.15 KEY68111.1 - 5.2e-20 71.4 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KEY68111.1 - 4.4e-14 51.4 2.9 0.0014 18.6 0.9 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY68111.1 - 2.3e-13 49.3 3.9 0.0038 17.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY68111.1 - 1.7e-08 34.0 0.6 0.00036 20.2 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KEY68111.1 - 6.2e-08 32.5 0.2 0.03 14.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY68111.1 - 1.9e-07 31.3 0.3 0.12 13.2 0.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY68111.1 - 1.1e-06 28.2 3.2 0.026 14.5 0.5 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY68111.1 - 1.2e-05 25.8 3.6 0.021 15.4 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY68111.1 - 2.5e-05 24.7 0.3 0.0069 16.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68111.1 - 0.00024 21.0 0.5 3.9 7.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY68111.1 - 0.00059 20.0 1.1 0.0013 18.9 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEY68111.1 - 0.00067 19.8 2.0 0.0017 18.5 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY68111.1 - 0.00098 19.4 5.4 0.042 14.1 1.6 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY68111.1 - 0.019 15.6 1.7 1.2 9.9 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KEY68111.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation CHIP_TPR_N PF18391.1 KEY68111.1 - 2.3 9.0 13.7 5.2 7.9 13.7 1.6 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain DIE2_ALG10 PF04922.12 KEY68113.1 - 1.3e-126 423.1 2.1 1.9e-126 422.6 2.1 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 KEY68113.1 - 4.5e-22 77.9 0.2 4.9e-21 74.5 0.0 2.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Med4 PF10018.9 KEY68114.1 - 4.3e-41 140.7 13.1 9.4e-41 139.6 13.1 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1013 PF06242.11 KEY68114.1 - 0.13 12.3 5.5 2.7 8.0 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) DUF4407 PF14362.6 KEY68114.1 - 0.24 10.7 7.0 1.8 7.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZnuA PF01297.17 KEY68114.1 - 0.44 9.9 2.7 3 7.2 0.4 2.4 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic CAF-1_p150 PF11600.8 KEY68114.1 - 0.58 9.8 24.5 1.2 8.9 24.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EMP70 PF02990.16 KEY68115.1 - 7e-202 671.7 7.5 1e-201 671.1 7.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 KEY68116.1 - 4.6e-17 62.4 1.6 1.2e-16 61.1 1.6 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CDV3 PF15359.6 KEY68116.1 - 0.0017 18.9 5.5 0.0017 18.9 5.5 2.0 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 DUF3069 PF11269.8 KEY68116.1 - 0.023 14.9 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Sin_N PF04801.13 KEY68117.1 - 1.2e-23 84.1 0.0 3e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.9 KEY68118.1 - 0 1299.5 1.6 0 1299.2 1.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 KEY68118.1 - 1.3 9.2 3.6 0.7 10.1 0.3 2.2 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Glyco_transf_15 PF01793.16 KEY68119.1 - 7.6e-132 439.5 6.7 9.3e-132 439.2 6.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 KEY68120.1 - 2.3e-29 101.3 1.1 2.9e-29 101.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KEY68120.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S12 Acyl-CoA_dh_1 PF00441.24 KEY68121.1 - 2e-40 138.4 4.4 2.9e-40 137.9 4.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEY68121.1 - 2.6e-30 105.4 0.8 8.8e-30 103.7 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEY68121.1 - 3.5e-24 84.8 0.0 7.3e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEY68121.1 - 1e-17 64.7 1.0 1.7e-17 63.9 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEY68121.1 - 0.00014 21.6 0.0 0.00044 20.0 0.0 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KEY68121.1 - 0.065 13.3 0.1 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Staphylococcal AgrD protein HR1 PF02185.16 KEY68122.1 - 2.9e-23 81.8 11.0 2.6e-11 43.5 0.7 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KEY68122.1 - 2.1e-17 62.7 36.5 5.6e-12 45.4 12.1 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KEY68122.1 - 0.0028 17.9 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 KEY68122.1 - 0.044 14.5 0.1 0.16 12.7 0.1 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain She9_MDM33 PF05546.11 KEY68123.1 - 4.9e-81 271.3 4.8 6.4e-81 270.9 4.8 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DUF4195 PF13836.6 KEY68123.1 - 0.11 12.6 4.3 0.18 11.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) ZapB PF06005.12 KEY68123.1 - 8.2 6.9 9.5 12 6.4 0.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB HAD PF12710.7 KEY68124.1 - 5.8e-23 82.3 0.0 7.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KEY68124.1 - 2.6e-05 23.9 0.0 5.1e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KEY68124.1 - 0.0053 17.1 0.3 0.17 12.1 0.0 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KEY68124.1 - 0.0096 15.3 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase eIF-1a PF01176.19 KEY68125.1 - 1e-19 70.1 0.1 1.5e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 KEY68126.1 - 3.9e-143 477.2 12.9 4.9e-143 476.9 12.9 1.1 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 KEY68126.1 - 3.1e-27 96.1 0.3 6.9e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thioredoxin PF00085.20 KEY68126.1 - 1.7e-22 79.4 0.0 2.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY68126.1 - 0.027 14.9 0.1 0.14 12.7 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEY68126.1 - 0.052 13.9 0.0 0.29 11.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KEY68126.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 KEY68126.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KEY68126.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Nuf2 PF03800.14 KEY68128.1 - 8.3e-42 142.6 0.1 3.6e-41 140.5 0.1 2.1 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KEY68128.1 - 2.5e-35 121.0 18.0 2.5e-35 121.0 18.0 4.4 4 1 1 5 5 5 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 KEY68128.1 - 1.7 8.5 23.3 0.12 12.2 4.4 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Adaptin_N PF01602.20 KEY68130.1 - 1.6e-105 353.7 0.0 2e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEY68130.1 - 2.1e-17 63.6 0.1 2.3e-15 57.0 0.0 3.0 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY68130.1 - 3.2e-11 43.5 3.4 5.3e-05 23.5 0.0 5.3 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KEY68130.1 - 6.5e-10 38.4 1.4 0.029 14.6 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.7 KEY68130.1 - 9e-05 22.7 1.9 0.053 13.8 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KEY68130.1 - 0.00076 19.9 1.2 0.76 10.3 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 KEY68130.1 - 0.003 17.1 0.3 3.5 7.1 0.0 3.2 2 1 0 3 3 3 1 CLASP N terminal CRISPR_Cse2 PF09485.10 KEY68130.1 - 0.028 15.0 3.7 4.6 7.8 0.8 3.5 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Cnd3 PF12719.7 KEY68130.1 - 0.25 10.5 1.4 1.1 8.4 0.5 2.4 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Autophagy_N PF03986.13 KEY68130.1 - 1.5 8.8 11.4 3.6 7.5 11.4 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RNA_pol_3_Rpc31 PF11705.8 KEY68130.1 - 2.6 8.3 26.9 4.9 7.4 26.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KEY68130.1 - 4.5 6.5 21.0 7.8 5.7 21.0 1.4 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 KEY68130.1 - 9.2 5.1 20.9 14 4.5 20.9 1.3 1 0 0 1 1 1 0 Paf1 RTA1 PF04479.13 KEY68131.1 - 2.9e-71 239.4 5.6 4.6e-71 238.7 5.6 1.3 1 0 0 1 1 1 1 RTA1 like protein NAD_binding_2 PF03446.15 KEY68132.1 - 2.6e-36 125.2 0.3 3.9e-36 124.6 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEY68132.1 - 7.6e-29 100.4 0.0 1.4e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KEY68132.1 - 8.2e-07 29.5 0.0 3.8e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KEY68132.1 - 5.1e-05 22.4 0.0 8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KEY68132.1 - 0.0001 23.1 0.0 0.00059 20.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.23 KEY68132.1 - 0.0035 17.4 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEY68132.1 - 0.031 14.5 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KEY68132.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KilA-N PF04383.13 KEY68133.1 - 0.0011 18.8 0.0 0.084 12.7 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain DIOX_N PF14226.6 KEY68133.1 - 0.072 13.8 0.8 0.13 13.0 0.8 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ATP-synt_G PF04718.15 KEY68133.1 - 0.24 12.2 4.9 1.3 9.9 0.1 2.6 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit VIT1 PF01988.19 KEY68133.1 - 2.3 8.0 9.0 0.27 11.1 4.0 1.9 1 1 1 2 2 2 0 VIT family Ribosomal_60s PF00428.19 KEY68134.1 - 4.6 7.9 11.3 2.5 8.7 8.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HEAT PF02985.22 KEY68135.1 - 0.33 11.3 3.0 5.4 7.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Sugar_tr PF00083.24 KEY68136.1 - 5.3e-86 289.2 18.7 6.2e-86 289.0 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68136.1 - 1.4e-37 129.5 42.4 2.5e-32 112.2 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY68136.1 - 2.9e-07 29.3 1.2 2.9e-07 29.3 1.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEY68136.1 - 1e-06 27.6 2.5 1e-06 27.6 2.5 3.4 3 1 0 3 3 3 1 MFS/sugar transport protein Phage_Coat_A PF05357.13 KEY68137.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage Coat Protein A TEA PF01285.18 KEY68138.1 - 0.098 12.7 0.2 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 TEA/ATTS domain Adaptin_N PF01602.20 KEY68139.1 - 2.5e-116 389.3 0.4 3.2e-116 389.0 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KEY68139.1 - 4.4e-57 192.5 3.8 9.6e-57 191.4 3.8 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KEY68139.1 - 1.7e-34 118.4 0.1 5.2e-34 116.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KEY68139.1 - 6.3e-17 61.7 2.7 4.1e-11 43.1 0.0 5.4 3 1 3 6 6 6 2 HEAT repeats Cnd1 PF12717.7 KEY68139.1 - 5.7e-07 29.7 8.6 0.049 13.7 0.1 4.9 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KEY68139.1 - 0.018 14.6 4.5 0.041 13.4 0.1 3.3 4 0 0 4 4 4 0 CLASP N terminal HEAT_PBS PF03130.16 KEY68139.1 - 0.026 15.2 0.0 52 4.9 0.0 4.5 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat DUF5010 PF16402.5 KEY68139.1 - 0.045 12.6 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) E2F_CC-MB PF16421.5 KEY68139.1 - 0.093 13.1 0.1 0.39 11.1 0.1 2.0 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain RTP1_C1 PF10363.9 KEY68139.1 - 0.14 12.3 0.3 7.3 6.8 0.0 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Med3 PF11593.8 KEY68139.1 - 0.24 10.6 3.4 0.4 9.8 3.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HEAT PF02985.22 KEY68139.1 - 0.3 11.5 7.9 2.3 8.7 0.2 5.2 5 0 0 5 5 5 0 HEAT repeat ATP12 PF07542.11 KEY68140.1 - 1.7e-41 141.3 0.1 2.7e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein UnbV_ASPIC PF07593.12 KEY68140.1 - 0.065 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 ASPIC and UnbV zf-HIT PF04438.16 KEY68141.1 - 0.23 11.4 5.5 0.054 13.4 1.7 2.0 2 0 0 2 2 2 0 HIT zinc finger Asp PF00026.23 KEY68143.1 - 1.8e-52 178.7 0.0 2.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY68143.1 - 1.2e-06 28.9 0.3 1.2e-06 28.9 0.3 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY68143.1 - 0.0014 19.3 2.2 12 6.7 0.0 4.1 4 0 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 KEY68143.1 - 0.068 13.7 0.1 35 5.0 0.0 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease AMP-binding PF00501.28 KEY68144.1 - 3.7e-76 256.4 0.0 4.7e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY68144.1 - 3.9e-14 53.4 1.0 1.2e-13 51.8 0.7 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CFEM PF05730.11 KEY68145.1 - 0.00017 21.6 1.7 0.00017 21.6 1.7 2.5 2 0 0 2 2 2 1 CFEM domain bVLRF1 PF18826.1 KEY68147.1 - 1.9e-62 209.5 0.2 4.4e-62 208.4 0.2 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KEY68147.1 - 0.001 19.3 0.1 0.0023 18.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_6 PF13912.6 KEY68147.1 - 1.9 8.6 5.1 0.29 11.2 1.3 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger MT0933_antitox PF14013.6 KEY68148.1 - 0.027 14.7 9.8 0.13 12.5 7.6 2.6 2 1 0 2 2 2 0 MT0933-like antitoxin protein Amino_oxidase PF01593.24 KEY68149.1 - 6.4e-22 78.4 0.1 7.7e-21 74.9 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY68149.1 - 1.1e-14 54.4 0.1 2.9e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68149.1 - 2.9e-10 40.3 0.0 6.4e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY68149.1 - 1.6e-07 30.9 0.0 2.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY68149.1 - 5e-06 25.9 3.3 2e-05 23.8 3.7 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEY68149.1 - 1.7e-05 23.7 0.1 0.0012 17.6 0.9 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEY68149.1 - 0.00037 20.0 2.6 0.00074 19.0 2.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY68149.1 - 0.00041 19.7 0.6 0.00072 18.9 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY68149.1 - 0.00066 19.0 1.5 0.00099 18.4 1.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY68149.1 - 0.0013 17.8 2.1 0.0036 16.4 1.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY68149.1 - 0.0014 18.7 0.6 0.017 15.1 0.5 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEY68149.1 - 0.0014 19.1 1.8 0.0072 16.9 1.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY68149.1 - 0.0074 15.5 0.3 0.012 14.8 0.3 1.2 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 KEY68149.1 - 0.014 15.0 0.5 0.026 14.1 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.18 KEY68149.1 - 0.074 11.6 0.1 7.8 4.9 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor GIDA PF01134.22 KEY68149.1 - 0.092 11.8 2.1 0.21 10.6 1.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A XdhC_C PF13478.6 KEY68149.1 - 0.11 13.0 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 KEY68149.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 KEY68149.1 - 0.28 10.6 0.8 0.44 10.0 0.8 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 KEY68149.1 - 0.33 10.8 0.8 0.55 10.1 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SQS_PSY PF00494.19 KEY68150.1 - 3.5e-64 216.9 0.2 5.5e-64 216.2 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase PufQ PF05398.11 KEY68150.1 - 1.7 8.8 4.0 0.73 10.0 0.1 2.2 2 0 0 2 2 2 0 PufQ cytochrome subunit Ank_2 PF12796.7 KEY68151.1 - 2.3e-45 153.1 13.4 4.3e-12 46.5 0.1 4.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68151.1 - 2.4e-33 114.1 1.4 2.7e-09 37.4 0.0 6.8 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KEY68151.1 - 2.8e-30 103.4 21.1 0.0014 19.0 0.0 9.4 9 2 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KEY68151.1 - 3.4e-30 103.7 10.3 2.7e-06 27.6 0.2 8.2 2 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68151.1 - 2.9e-26 88.6 0.8 0.15 12.7 0.0 10.0 10 1 1 11 11 11 6 Ankyrin repeat Se-cys_synth_N PF12390.8 KEY68151.1 - 0.0064 16.7 0.6 1.3 9.3 0.0 4.5 4 1 0 4 4 4 1 Selenocysteine synthase N terminal DUF2857 PF11198.8 KEY68151.1 - 0.024 14.4 0.9 3.6 7.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2857) GUN4_N PF16416.5 KEY68151.1 - 0.11 12.5 3.8 6.1 6.9 0.1 4.9 7 1 0 7 7 7 0 ARM-like repeat domain, GUN4-N terminal Goodbye PF17109.5 KEY68152.1 - 5.6e-05 23.6 1.5 0.00012 22.5 0.1 2.0 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain LTXXQ PF07813.12 KEY68152.1 - 0.025 15.3 3.1 1.8 9.3 0.0 2.5 2 1 0 2 2 2 0 LTXXQ motif family protein DUF2357 PF09823.9 KEY68152.1 - 0.026 13.8 1.7 0.043 13.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Hs1pro-1_C PF07014.12 KEY68152.1 - 0.045 13.2 0.9 0.072 12.6 0.1 1.7 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus DUF5063 PF16702.5 KEY68152.1 - 0.059 13.8 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) WXG100 PF06013.12 KEY68152.1 - 0.078 13.2 1.4 0.29 11.4 0.3 2.5 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF2524 PF10732.9 KEY68152.1 - 0.089 13.1 4.4 7.2 7.0 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) DUF16 PF01519.16 KEY68152.1 - 0.64 10.5 4.7 0.54 10.8 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 FAD_binding_7 PF03441.14 KEY68153.1 - 5.8e-45 153.3 0.1 9.1e-45 152.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KEY68153.1 - 6.5e-22 78.3 0.0 1.2e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase MmgE_PrpD PF03972.14 KEY68154.1 - 6.6e-148 492.9 0.4 8.4e-148 492.5 0.0 1.3 2 0 0 2 2 2 1 MmgE/PrpD family SH3_1 PF00018.28 KEY68155.1 - 6.9e-12 44.8 0.1 1.1e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEY68155.1 - 3.9e-09 36.2 0.1 7.1e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEY68155.1 - 1.2e-07 31.3 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 KEY68155.1 - 3.2 7.7 16.9 1.3 9.0 10.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) CMS1 PF14617.6 KEY68156.1 - 1.3e-77 260.5 6.0 7.2e-76 254.8 6.0 2.0 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KEY68156.1 - 3.6e-08 33.4 0.0 6.8e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CFEM PF05730.11 KEY68157.1 - 0.0021 18.1 3.7 0.0021 18.1 3.7 1.7 2 0 0 2 2 2 1 CFEM domain Ras PF00071.22 KEY68158.1 - 2e-49 167.3 0.0 1e-47 161.7 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY68158.1 - 7.4e-20 71.4 0.0 2e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY68158.1 - 3e-05 23.6 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family DAP3 PF10236.9 KEY68158.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RRM_1 PF00076.22 KEY68159.1 - 6.2e-10 38.8 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.12 KEY68159.1 - 0.00027 19.7 54.1 0.00027 19.7 54.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase_Tyr PF07714.17 KEY68160.1 - 1.9e-15 56.9 0.0 3.2e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY68160.1 - 2.4e-10 40.3 0.0 7.6e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEY68160.1 - 0.0028 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEY68160.1 - 0.2 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_61 PF03443.14 KEY68162.1 - 2.9e-63 213.5 0.1 3.6e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Metallophos PF00149.28 KEY68163.1 - 3.7e-18 66.8 0.1 6.8e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY68163.1 - 4e-06 27.1 0.0 9.1e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.27 KEY68164.1 - 3.7e-14 52.1 0.2 6.4e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KEY68164.1 - 1.8e-05 24.5 2.5 1.8e-05 24.5 2.5 2.2 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KEY68164.1 - 0.0037 16.9 0.2 0.0081 15.9 0.2 1.6 1 1 0 1 1 1 1 HeH/LEM domain Methyltransf_11 PF08241.12 KEY68166.1 - 0.0048 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68166.1 - 0.018 15.7 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1658 PF07871.11 KEY68166.1 - 0.89 9.6 6.8 4.3 7.4 0.2 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1658) GCD14 PF08704.10 KEY68167.1 - 0.19 11.4 0.0 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Clr5 PF14420.6 KEY68168.1 - 3e-23 81.8 0.4 8.5e-23 80.3 0.4 1.8 1 0 0 1 1 1 1 Clr5 domain Pkinase PF00069.25 KEY68169.1 - 6.4e-45 153.6 0.0 3.6e-44 151.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68169.1 - 2.7e-27 95.7 0.0 4.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY68169.1 - 0.0095 14.8 0.1 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEY68169.1 - 0.039 13.9 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY68169.1 - 0.22 10.8 0.0 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.6 KEY68170.1 - 6.5e-20 71.1 0.9 1.7e-19 69.8 0.9 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KEY68170.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY68170.1 - 0.13 12.5 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TERB2 PF15101.6 KEY68171.1 - 0.058 13.5 2.4 0.071 13.2 2.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 KEY68171.1 - 2.9 7.8 14.5 3.1 7.7 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 KEY68172.1 - 4.2e-05 24.1 0.0 0.00012 22.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68172.1 - 0.053 14.1 0.0 0.21 12.2 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 KEY68172.1 - 0.098 13.2 0.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat zf-C2H2 PF00096.26 KEY68172.1 - 0.54 10.8 7.2 0.12 12.8 2.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_primase_lrg PF04104.14 KEY68173.1 - 3.6e-85 285.6 0.1 6e-85 284.9 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit zf-FPG_IleRS PF06827.14 KEY68174.1 - 0.0032 17.3 0.7 0.082 12.8 0.0 2.3 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Mut7-C PF01927.16 KEY68174.1 - 0.01 15.9 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-RRPl_C4 PF17026.5 KEY68174.1 - 0.039 14.1 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf_UBZ PF18439.1 KEY68174.1 - 0.16 11.6 0.9 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1660 PF07874.11 KEY68174.1 - 0.16 12.4 2.7 2.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Prophage protein (DUF1660) zinc_ribbon_9 PF14369.6 KEY68174.1 - 0.26 11.6 3.2 5.4 7.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon Thioredoxin PF00085.20 KEY68175.1 - 3.7e-22 78.2 0.0 4.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY68175.1 - 2.5e-06 27.9 0.1 6.2e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEY68175.1 - 2e-05 24.8 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KEY68175.1 - 0.00012 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KEY68175.1 - 0.0054 16.6 0.1 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KEY68175.1 - 0.0062 16.7 0.1 0.009 16.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KEY68175.1 - 0.0075 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KEY68175.1 - 0.019 15.0 0.1 0.66 10.1 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin domain HyaE PF07449.11 KEY68175.1 - 0.029 14.3 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.16 KEY68175.1 - 0.059 12.3 0.0 0.069 12.1 0.0 1.0 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.10 KEY68175.1 - 0.096 12.4 0.2 0.17 11.6 0.2 1.5 1 1 0 1 1 1 0 Redoxin GHMP_kinases_C PF08544.13 KEY68176.1 - 0.0009 19.6 0.4 0.2 12.1 0.2 2.6 1 1 1 2 2 2 2 GHMP kinases C terminal Baculo_PEP_C PF04513.12 KEY68176.1 - 0.048 13.7 7.2 0.22 11.6 1.1 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TrbL PF04610.14 KEY68176.1 - 0.092 12.5 8.9 0.26 11.0 2.6 2.4 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein PuR_N PF09182.10 KEY68176.1 - 0.33 10.9 2.0 0.4 10.6 0.5 1.9 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal FIVAR PF07554.13 KEY68176.1 - 1.9 9.3 9.2 1.6 9.5 1.6 3.5 3 1 0 3 3 3 0 FIVAR domain FBPase PF00316.20 KEY68177.1 - 2.9e-23 82.3 0.0 4.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain GST_N PF02798.20 KEY68179.1 - 3e-17 62.7 0.1 8.2e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY68179.1 - 2.9e-13 50.0 0.0 5.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY68179.1 - 1.2e-11 44.8 0.0 4.7e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY68179.1 - 5.8e-09 36.0 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY68179.1 - 3.9e-08 33.2 0.0 8.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY68179.1 - 3.4e-07 30.4 0.0 7.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KEY68179.1 - 0.0078 16.9 0.0 0.57 10.9 0.0 3.0 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KEY68179.1 - 0.08 13.2 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin Metallophos PF00149.28 KEY68181.1 - 5.7e-12 46.6 0.0 1.4e-11 45.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY68181.1 - 0.00013 22.2 0.1 0.018 15.2 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 KEY68182.1 - 6.8e-21 74.2 2.6 2.6e-20 72.3 1.6 2.6 2 0 0 2 2 2 1 DnaJ domain GST_N PF02798.20 KEY68183.1 - 5.4e-13 49.1 0.0 8.9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY68183.1 - 2e-12 47.1 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY68183.1 - 2.9e-12 46.8 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY68183.1 - 1.1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEY68183.1 - 3.4e-08 33.7 0.0 7.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY68183.1 - 5.3e-06 26.4 0.0 1.8e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY68183.1 - 0.021 15.4 0.1 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NAD_binding_4 PF07993.12 KEY68184.1 - 7.5e-66 221.9 0.0 1.1e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEY68184.1 - 4.4e-63 213.3 0.0 7.7e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KEY68184.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KEY68184.1 - 2.2e-09 37.5 0.0 6.2e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KEY68184.1 - 2.9e-07 29.8 0.0 5.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KEY68184.1 - 4.5e-05 24.3 0.0 0.00021 22.2 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KEY68184.1 - 0.0014 17.8 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEY68184.1 - 0.0061 16.5 0.4 0.051 13.5 0.4 2.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEY68184.1 - 0.14 11.3 0.2 1.1 8.3 0.2 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KEY68184.1 - 0.17 11.8 0.2 0.57 10.1 0.2 1.8 1 1 0 1 1 1 0 KR domain Peptidase_M28 PF04389.17 KEY68187.1 - 1.7e-35 122.5 0.0 2.3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY68187.1 - 6.9e-12 45.2 0.9 1.7e-11 44.0 0.9 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY68187.1 - 0.00033 20.4 0.1 0.001 18.8 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HATPase_c_3 PF13589.6 KEY68188.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3632 PF12311.8 KEY68190.1 - 3.2e-17 63.5 0.0 4.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.11 KEY68191.1 - 8.8e-23 81.3 0.0 1.4e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY68192.1 - 3.9e-13 49.8 0.0 2e-10 41.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY68192.1 - 1e-11 44.8 0.3 4.6e-05 23.6 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY68192.1 - 3.6e-10 40.2 0.3 5.6e-06 26.8 0.0 4.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68192.1 - 4.5e-09 35.8 0.1 1.5 9.6 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.12 KEY68192.1 - 8e-07 29.1 0.0 5.8e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEY68192.1 - 1.2e-06 29.1 0.0 1.7e-05 25.2 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY68192.1 - 8.1e-06 26.1 0.0 0.0001 22.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEY68192.1 - 0.0043 17.4 0.0 0.71 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RWD PF05773.22 KEY68192.1 - 0.023 15.0 0.1 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 RWD domain Ank PF00023.30 KEY68192.1 - 0.024 15.1 0.0 4.1 8.0 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat AAA PF00004.29 KEY68192.1 - 0.031 14.7 0.0 0.28 11.6 0.0 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEY68192.1 - 0.032 14.1 0.0 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Kinesin PF00225.23 KEY68192.1 - 0.054 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain PutA_N PF18083.1 KEY68192.1 - 0.099 12.7 0.0 0.5 10.4 0.0 2.3 1 0 0 1 1 1 0 Proline utilization A N-terminal domain Abhydrolase_3 PF07859.13 KEY68193.1 - 3.4e-12 46.7 0.1 4.9e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_11 PF08241.12 KEY68193.1 - 6.2e-10 39.6 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68193.1 - 5e-09 36.8 0.0 1.3e-07 32.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68193.1 - 9.5e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY68193.1 - 0.013 16.2 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEY68193.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain HET PF06985.11 KEY68194.1 - 3.5e-31 108.5 0.0 1.1e-30 107.0 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SnoaL PF07366.12 KEY68195.1 - 2.4e-30 104.9 0.0 3.4e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY68195.1 - 1e-09 38.9 0.0 0.00014 22.5 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain PNP_UDP_1 PF01048.20 KEY68196.1 - 8.6e-14 51.3 0.1 2e-13 50.1 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily DNA_binding_1 PF01035.20 KEY68197.1 - 1.7e-22 79.4 0.0 2.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Kinesin PF00225.23 KEY68198.1 - 2.3e-93 312.8 0.0 2.3e-93 312.8 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEY68198.1 - 1.2e-18 67.5 0.0 2e-15 57.0 0.0 3.3 2 0 0 2 2 2 2 Microtubule binding DsrC PF04358.13 KEY68198.1 - 0.73 10.4 4.5 0.51 10.9 0.6 3.0 2 0 0 2 2 2 0 DsrC like protein Hemagglutinin PF00509.18 KEY68198.1 - 2.1 6.6 5.2 3.7 5.9 2.8 2.5 2 0 0 2 2 2 0 Haemagglutinin ERCC4 PF02732.15 KEY68200.1 - 7.7e-25 87.9 0.1 1.5e-24 87.0 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Peptidase_S49_N PF08496.10 KEY68200.1 - 0.35 10.9 6.8 0.72 9.9 6.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 KEY68200.1 - 0.75 9.6 6.4 1.6 8.5 6.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4355 PF14265.6 KEY68200.1 - 1.8 8.8 17.6 0.19 12.0 12.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) PNP_UDP_1 PF01048.20 KEY68204.1 - 3.8e-14 52.5 0.0 7e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily Zn_clus PF00172.18 KEY68205.1 - 0.0037 17.4 1.6 0.0065 16.6 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 KEY68207.1 - 4.1e-11 42.9 0.8 6.1e-10 39.1 0.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) BT1 PF03092.16 KEY68207.1 - 0.21 9.8 0.0 0.4 8.9 0.0 1.3 2 0 0 2 2 2 0 BT1 family CiPC PF15800.5 KEY68207.1 - 1 9.0 6.5 1.4 8.6 6.5 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian bZIP_1 PF00170.21 KEY68207.1 - 3.9 7.6 10.3 6.4 7.0 10.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KEY68207.1 - 4.4 7.5 10.0 7.2 6.8 10.0 1.2 1 0 0 1 1 1 0 Basic region leucine zipper NmrA PF05368.13 KEY68208.1 - 1.1e-34 120.1 0.0 1.6e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY68208.1 - 7.3e-14 52.1 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY68208.1 - 8.7e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY68208.1 - 0.042 12.8 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEY68208.1 - 0.042 14.3 0.0 0.099 13.1 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEY68208.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 4HBT_3 PF13622.6 KEY68209.1 - 5.2e-44 151.4 4.1 6.1e-44 151.1 4.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.22 KEY68210.1 - 3.9e-28 98.4 0.0 7.7e-28 97.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Glycophorin_A PF01102.18 KEY68211.1 - 0.017 15.3 0.3 0.03 14.6 0.2 1.4 1 1 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 KEY68211.1 - 0.051 14.5 0.0 0.15 13.0 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3 PF06040.11 KEY68211.1 - 0.091 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 protein HOK_GEF PF01848.16 KEY68211.1 - 0.12 11.8 0.8 0.21 11.0 0.8 1.4 1 0 0 1 1 1 0 Hok/gef family Beta-APP PF03494.13 KEY68211.1 - 0.31 10.9 3.2 0.56 10.1 3.2 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) MGC-24 PF05283.11 KEY68211.1 - 1.4 9.4 5.0 4.7 7.7 5.0 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CAP59_mtransfer PF11735.8 KEY68212.1 - 6.1e-65 219.3 0.0 8.3e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.18 KEY68213.1 - 5.1e-06 26.0 0.2 1.1e-05 25.0 0.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_N PF08240.12 KEY68214.1 - 1.1e-24 86.4 1.5 2.5e-24 85.3 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY68214.1 - 6.2e-09 35.9 0.8 0.00017 21.6 0.0 3.3 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEY68214.1 - 2.6e-08 33.6 0.6 2.6e-08 33.6 0.6 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated Lipase_3 PF01764.25 KEY68215.1 - 3.4e-18 65.9 0.0 5.8e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY68215.1 - 6.4e-05 23.7 0.0 0.00022 21.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEY68215.1 - 0.0033 17.2 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 KEY68215.1 - 0.0057 16.2 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 KEY68215.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KEY68215.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.8 KEY68215.1 - 0.086 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Rft-1 PF04506.13 KEY68216.1 - 2.3e-150 501.7 13.3 2.7e-150 501.5 13.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KEY68216.1 - 2.3e-09 37.0 15.4 2.3e-09 37.0 15.4 2.3 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KEY68216.1 - 0.00072 18.9 9.5 0.00072 18.9 9.5 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DUF5464 PF17552.2 KEY68216.1 - 0.57 10.5 7.9 3 8.2 1.8 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5464) DEAD PF00270.29 KEY68217.1 - 2.2e-51 174.1 0.0 4.8e-51 173.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68217.1 - 8.2e-35 119.5 0.0 2.5e-30 105.1 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KEY68217.1 - 0.0018 17.1 0.0 0.0096 14.7 0.0 2.1 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HORMA PF02301.18 KEY68218.1 - 4.8e-30 104.7 0.0 6.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DUF2660 PF10859.8 KEY68218.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Med21 PF11221.8 KEY68218.1 - 0.17 12.1 0.4 0.34 11.2 0.4 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Mucin PF01456.17 KEY68218.1 - 0.7 9.9 7.3 0.12 12.3 0.7 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.29 KEY68219.1 - 6.9e-38 130.6 0.0 9.9e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KEY68219.1 - 3.7e-23 81.0 0.1 7.1e-13 48.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 KEY68219.1 - 1.6e-21 75.8 1.4 1.1e-20 73.1 0.1 2.4 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KEY68219.1 - 1.8e-19 69.8 12.0 1.1e-18 67.3 1.3 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KEY68219.1 - 7.5e-15 55.3 0.5 4.2e-13 49.6 0.1 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase NifU_N PF01592.16 KEY68220.1 - 7.9e-54 181.2 0.0 1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain bMG5 PF17972.1 KEY68220.1 - 0.073 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain RPE65 PF03055.15 KEY68221.1 - 1.8e-114 383.5 0.0 2.3e-114 383.1 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pkinase PF00069.25 KEY68222.1 - 2.9e-14 53.1 0.0 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68222.1 - 1.3e-08 34.4 0.0 5e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase zf-C2H2_11 PF16622.5 KEY68223.1 - 0.085 12.6 1.2 0.16 11.7 1.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Glyco_hydro_3_C PF01915.22 KEY68225.1 - 1.1e-60 205.1 0.0 1.9e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY68225.1 - 5e-42 144.4 0.0 8.5e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY68225.1 - 2.1e-24 85.4 1.0 8.4e-24 83.5 0.1 2.5 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KEY68225.1 - 8.3e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.6 KEY68226.1 - 4.3e-59 199.8 0.0 5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nup54 PF13874.6 KEY68226.1 - 0.014 15.5 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3138 PF11336.8 KEY68226.1 - 0.23 10.0 0.6 0.38 9.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Glyco_hydro_31 PF01055.26 KEY68227.1 - 1.7e-156 521.8 6.1 2.5e-156 521.3 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KEY68227.1 - 4.1e-39 133.4 0.0 1.4e-38 131.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KEY68227.1 - 3.8e-16 59.2 0.7 3.8e-16 59.2 0.7 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like zf-C2H2 PF00096.26 KEY68228.1 - 7.9e-05 22.9 15.4 0.059 13.8 2.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type Sina PF03145.16 KEY68228.1 - 0.04 13.9 5.1 0.07 13.1 5.1 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 KEY68228.1 - 0.093 13.6 21.2 0.15 13.0 1.9 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY68228.1 - 0.34 11.3 6.6 4.3 7.7 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KEY68228.1 - 0.55 11.0 4.9 0.13 12.9 0.9 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger Patatin PF01734.22 KEY68229.1 - 1.7e-14 54.5 0.0 7.5e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.8 KEY68230.1 - 8.3e-07 28.2 0.1 1.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rtt102p PF09510.10 KEY68230.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein GFO_IDH_MocA PF01408.22 KEY68231.1 - 1.2e-17 64.8 0.0 2.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KEY68231.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 4HBT PF03061.22 KEY68232.1 - 1.4e-07 31.8 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KEY68232.1 - 6e-07 30.0 0.0 8.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KEY68232.1 - 0.00015 21.1 0.7 0.00026 20.3 0.7 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.22 KEY68233.1 - 3.6e-30 105.2 0.0 7.7e-30 104.1 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KEY68233.1 - 0.034 13.8 0.1 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 S4 domain Peptidase_U32 PF01136.19 KEY68233.1 - 0.056 12.6 0.2 6.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family U32 bZIP_1 PF00170.21 KEY68234.1 - 0.011 15.8 12.3 0.048 13.8 12.4 1.8 1 1 1 2 2 2 0 bZIP transcription factor DUF5595 PF18077.1 KEY68234.1 - 0.17 12.0 3.0 0.28 11.3 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Spc7 PF08317.11 KEY68234.1 - 0.54 9.1 6.7 0.77 8.6 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_Xtn PF12848.7 KEY68234.1 - 2.8 8.0 9.8 4.8 7.3 9.8 1.3 1 0 0 1 1 1 0 ABC transporter Zn_Tnp_IS1 PF03811.13 KEY68235.1 - 0.19 11.5 2.0 0.29 10.9 2.0 1.3 1 0 0 1 1 1 0 InsA N-terminal domain Cu-oxidase_2 PF07731.14 KEY68236.1 - 3.6e-24 85.0 1.3 1.1e-22 80.2 1.3 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY68236.1 - 2.5e-15 56.5 0.0 7.7e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY68236.1 - 0.00046 20.3 0.0 0.0016 18.6 0.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase DUF4763 PF15960.5 KEY68238.1 - 0.0028 17.0 1.0 0.0028 17.0 1.0 3.2 3 1 0 4 4 4 1 Domain of unknown function (DUF4763) Ndc1_Nup PF09531.10 KEY68238.1 - 2.1 6.9 7.9 3 6.4 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Basic PF01586.16 KEY68238.1 - 2.1 9.5 5.6 4.3 8.6 0.2 2.7 2 0 0 2 2 2 0 Myogenic Basic domain zf-UBR PF02207.20 KEY68239.1 - 1.8e-13 50.5 6.6 1.8e-13 50.5 6.6 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 KEY68240.1 - 9.1e-100 332.4 1.5 2.8e-99 330.7 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEY68240.1 - 3.8e-39 133.4 0.1 6.8e-39 132.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KEY68240.1 - 1.6e-33 116.1 31.5 1.6e-33 116.1 31.5 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KEY68240.1 - 8.5e-26 90.2 0.6 2.3e-25 88.8 0.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY68240.1 - 9.7e-15 55.0 0.1 2.2e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEY68240.1 - 1.5e-07 31.0 0.0 6.5e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEY68240.1 - 2.2e-05 24.4 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KEY68240.1 - 0.0062 16.2 0.2 0.044 13.5 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEY68240.1 - 0.0068 16.3 0.0 0.028 14.3 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.7 KEY68240.1 - 0.19 12.4 0.7 0.49 11.1 0.7 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.10 KEY68240.1 - 0.21 11.7 1.4 0.49 10.5 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-TFIIB PF13453.6 KEY68240.1 - 0.44 9.9 1.6 0.96 8.8 1.6 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_16 PF13191.6 KEY68240.1 - 0.68 10.3 0.0 0.68 10.3 0.0 2.4 2 0 0 2 2 1 0 AAA ATPase domain DUF4386 PF14329.6 KEY68241.1 - 0.19 11.6 4.7 0.42 10.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4386) Sugar_tr PF00083.24 KEY68243.1 - 2.4e-115 386.0 27.6 2.8e-115 385.8 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68243.1 - 4.7e-17 62.0 34.2 4.7e-17 62.0 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C2 PF00648.21 KEY68244.1 - 5e-61 206.3 1.5 1e-59 202.0 1.5 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease TSP_NTD PF17804.1 KEY68244.1 - 2.8 8.2 16.3 0.4 10.9 11.4 2.0 2 0 0 2 2 2 0 Tail specific protease N-terminal domain zf-CCHC PF00098.23 KEY68245.1 - 2.7e-45 150.5 60.8 5.8e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KEY68245.1 - 5.1e-10 38.9 39.0 0.16 11.7 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KEY68245.1 - 8.1e-05 22.5 44.0 0.061 13.3 0.2 6.9 3 2 2 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.6 KEY68245.1 - 0.00027 20.6 45.1 0.0068 16.1 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KEY68245.1 - 0.058 13.2 2.0 0.058 13.2 2.0 7.2 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 KEY68245.1 - 0.068 13.0 0.2 0.068 13.0 0.2 6.9 6 1 1 7 7 7 0 Zinc knuckle ABC2_membrane_3 PF12698.7 KEY68246.1 - 5.6 6.0 5.6 8.1 5.4 5.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 KEY68247.1 - 2.7e-37 126.1 0.8 4.3e-05 24.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY68247.1 - 1.7e-12 47.5 0.1 0.013 15.8 0.0 4.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KEY68247.1 - 0.0025 16.7 0.9 4.7 5.9 0.2 3.2 1 1 3 4 4 4 2 Nup133 N terminal like SGL PF08450.12 KEY68247.1 - 0.05 13.2 0.3 0.36 10.4 0.2 2.4 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region BBS2_Mid PF14783.6 KEY68247.1 - 0.052 13.6 0.0 18 5.4 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KEY68247.1 - 0.12 11.4 0.1 31 3.4 0.1 3.2 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY68247.1 - 0.13 11.6 0.1 4.2 6.6 0.0 2.4 1 1 2 3 3 3 0 WD40-like domain TRAPP PF04051.16 KEY68248.1 - 1.8e-35 121.8 0.0 2.1e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KEY68248.1 - 0.0018 17.2 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KEY68248.1 - 0.064 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Glyco_hydro_16 PF00722.21 KEY68250.1 - 6.2e-16 58.4 0.2 8.5e-16 57.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEY68250.1 - 1.2e-08 33.9 0.1 0.0012 17.4 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KEY68250.1 - 0.09 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) TFB6 PF17110.5 KEY68251.1 - 7e-65 217.9 0.0 8.4e-65 217.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH STE2 PF02116.15 KEY68253.1 - 7.8e-88 294.4 24.4 9.1e-88 294.2 24.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 KEY68254.1 - 1.7e-29 102.2 0.2 2.7e-29 101.5 0.2 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KEY68254.1 - 4.2e-22 77.9 0.0 9.8e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KEY68254.1 - 0.03 14.0 0.3 0.06 13.0 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme IDO PF01231.18 KEY68255.1 - 5.1e-170 566.0 0.0 5.8e-170 565.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RNA_pol_Rpb2_6 PF00562.28 KEY68256.1 - 8.3e-125 416.9 0.1 1.5e-124 416.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEY68256.1 - 1.4e-49 168.4 0.0 4.5e-49 166.7 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KEY68256.1 - 4.8e-45 153.5 0.0 1e-44 152.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KEY68256.1 - 1.3e-33 115.2 0.1 3e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KEY68256.1 - 2e-25 88.7 0.1 4.9e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEY68256.1 - 6e-24 84.4 0.3 1.7e-23 82.9 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KEY68256.1 - 2.7e-20 72.4 0.8 6e-20 71.3 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KEY68256.1 - 1.2 9.5 3.2 14 6.0 0.3 3.4 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain PET117 PF15786.5 KEY68257.1 - 6e-25 87.3 3.2 7.2e-25 87.0 3.2 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KEY68258.1 - 5.6e-33 113.6 18.4 6.4e-33 113.4 18.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KEY68258.1 - 0.016 15.3 12.4 0.016 15.3 12.4 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 KEY68258.1 - 0.052 14.0 17.5 0.082 13.3 17.5 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP11 PF06644.11 KEY68258.1 - 0.066 13.0 11.4 0.075 12.8 11.4 1.0 1 0 0 1 1 1 0 ATP11 protein DUF2362 PF10154.9 KEY68258.1 - 0.067 12.1 5.3 0.082 11.8 5.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF1834 PF08873.11 KEY68258.1 - 0.095 12.4 0.9 0.12 12.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) PIN_8 PF18476.1 KEY68258.1 - 0.14 12.0 8.4 0.16 11.8 8.4 1.1 1 0 0 1 1 1 0 PIN like domain YusW PF14039.6 KEY68258.1 - 0.17 12.4 8.2 0.15 12.5 7.3 1.4 1 1 0 1 1 1 0 YusW-like protein DUF2203 PF09969.9 KEY68258.1 - 0.2 12.4 6.4 0.26 12.0 6.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3552 PF12072.8 KEY68258.1 - 0.52 9.7 21.5 0.037 13.4 14.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CemA PF03040.14 KEY68258.1 - 0.95 9.3 5.2 1.1 9.1 5.2 1.1 1 0 0 1 1 1 0 CemA family pRN1_helical PF13010.6 KEY68258.1 - 2.1 8.3 11.5 0.42 10.6 7.1 1.8 1 1 1 2 2 2 0 Primase helical domain RRF PF01765.19 KEY68258.1 - 6 6.8 17.9 12 5.8 17.9 1.5 1 1 0 1 1 1 0 Ribosome recycling factor vATP-synt_E PF01991.18 KEY68258.1 - 6.1 6.2 20.4 92 2.3 20.4 2.0 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF3450 PF11932.8 KEY68258.1 - 6.7 5.9 12.6 7.4 5.8 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CTNNBL PF08216.11 KEY68259.1 - 1.8e-39 134.1 0.1 1.4e-38 131.3 0.0 2.6 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KEY68259.1 - 0.031 14.3 1.8 14 5.9 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KEY68259.1 - 0.048 13.0 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Mo25-like Arm_2 PF04826.13 KEY68259.1 - 0.13 11.7 0.3 2.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Armadillo-like MIT PF04212.18 KEY68260.1 - 2.4e-14 53.1 2.7 4.6e-14 52.2 2.7 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cellulase PF00150.18 KEY68261.1 - 8.7e-16 58.2 2.3 1.1e-15 57.8 2.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KEY68261.1 - 1e-12 47.7 11.1 2.6e-12 46.5 11.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 KEY68261.1 - 0.0029 17.0 0.1 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KEY68261.1 - 0.0039 16.3 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_10 PF00331.20 KEY68261.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Hfq PF17209.3 KEY68261.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Patatin PF01734.22 KEY68262.1 - 3.7e-25 89.3 0.2 8e-25 88.2 0.2 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Bac_luciferase PF00296.20 KEY68263.1 - 1e-55 189.4 0.2 1.3e-55 189.0 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase wnt PF00110.19 KEY68263.1 - 0.22 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 wnt family ADH_N PF08240.12 KEY68265.1 - 2.9e-10 40.0 0.0 9.5e-10 38.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY68265.1 - 7e-09 35.8 0.4 1.4e-08 34.7 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.15 KEY68266.1 - 4.7e-66 223.4 35.1 5.4e-66 223.2 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 KEY68267.1 - 5.9e-39 134.0 21.0 8.1e-39 133.5 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68267.1 - 1.9e-13 50.1 5.9 1.9e-13 50.1 5.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KEY68267.1 - 0.031 12.6 4.4 0.083 11.2 0.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.20 KEY68268.1 - 2.5e-54 184.8 0.0 3.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Zn_clus PF00172.18 KEY68269.1 - 7.5e-09 35.6 8.8 1.4e-08 34.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAP PF00956.18 KEY68270.1 - 9.1e-27 93.9 1.4 1.5e-26 93.2 1.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 KEY68270.1 - 0.069 12.9 12.3 0.11 12.2 12.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Arm-DNA-bind_3 PF13356.6 KEY68270.1 - 5.5 7.4 7.2 22 5.5 1.6 2.6 1 1 0 2 2 2 0 Arm DNA-binding domain DHHA2 PF02833.14 KEY68271.1 - 1e-16 61.4 0.1 1.6e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KEY68271.1 - 9.9e-09 35.4 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 DHH family Aldo_ket_red PF00248.21 KEY68272.1 - 4.4e-60 203.4 0.0 5.5e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 KEY68272.1 - 0.009 16.2 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 1 FliG middle domain MFS_1 PF07690.16 KEY68273.1 - 1.5e-29 103.0 59.6 5.9e-24 84.6 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68273.1 - 2.8e-09 36.3 26.9 3.6e-05 22.8 9.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter SET PF00856.28 KEY68274.1 - 1.9e-13 51.2 0.1 1e-12 48.7 0.1 2.1 1 1 0 1 1 1 1 SET domain TRAP-gamma PF07074.12 KEY68275.1 - 2.3 7.7 4.1 28 4.2 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) p450 PF00067.22 KEY68276.1 - 2.4e-54 184.8 0.0 3.6e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY68277.1 - 2e-37 129.1 0.0 2.9e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY68278.1 - 1.2e-23 83.6 0.0 1.9e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 KEY68279.1 - 5.9e-11 42.3 0.4 1.7e-10 40.8 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY68279.1 - 1e-06 28.1 0.1 1.2e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEY68279.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEY68279.1 - 0.0001 22.0 0.6 0.00015 21.4 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KEY68279.1 - 0.00033 19.7 0.0 0.00062 18.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0253 PF06786.12 KEY68279.1 - 0.14 12.5 0.2 0.36 11.1 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Ank_2 PF12796.7 KEY68280.1 - 1.8e-42 143.8 0.9 9.8e-11 42.1 0.1 6.4 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY68280.1 - 3.2e-29 97.7 11.6 3.6e-07 30.0 0.0 11.6 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 KEY68280.1 - 8.5e-24 82.9 19.3 1.1e-05 25.7 0.1 10.4 9 1 1 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KEY68280.1 - 6e-23 80.9 7.2 6.9e-05 23.3 0.4 8.1 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY68280.1 - 7.1e-21 74.0 5.9 1.2e-06 28.6 0.4 8.0 6 2 3 9 9 9 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 KEY68280.1 - 6.2e-06 26.5 0.0 2.1e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEY68280.1 - 1.9e-05 24.7 0.0 7.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KEY68280.1 - 0.013 14.7 0.0 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PLU-1 PF08429.11 KEY68280.1 - 0.038 13.2 0.3 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 PLU-1-like protein STE2 PF02116.15 KEY68281.1 - 0.81 8.9 13.7 1.7 7.9 9.3 2.1 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR GMC_oxred_N PF00732.19 KEY68282.1 - 1.6e-44 152.5 0.0 2.5e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY68282.1 - 1.8e-21 77.1 0.0 3.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY68282.1 - 0.0002 20.6 0.0 0.00077 18.6 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY68282.1 - 0.00022 20.5 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEY68282.1 - 0.0018 18.5 0.2 0.005 17.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68282.1 - 0.0046 16.6 3.8 0.0089 15.6 0.7 2.7 2 2 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY68282.1 - 0.0086 15.3 0.0 0.04 13.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY68282.1 - 0.012 14.9 0.1 0.056 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY68282.1 - 0.012 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KEY68282.1 - 0.014 15.6 0.1 0.077 13.3 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Malic_M PF03949.15 KEY68282.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.6 KEY68282.1 - 0.16 12.0 0.0 0.91 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY68282.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEY68282.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Podoplanin PF05808.11 KEY68283.1 - 0.0087 16.2 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 KEY68283.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KEY68283.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KEY68283.1 - 0.1 12.5 0.9 0.21 11.5 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain ADH_N PF08240.12 KEY68284.1 - 4.4e-29 100.6 0.3 7.2e-29 99.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY68284.1 - 8.6e-24 84.0 0.1 1.3e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68284.1 - 0.00047 21.2 0.0 0.00078 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KEY68284.1 - 0.069 12.9 0.9 0.85 9.3 1.0 2.1 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 KEY68284.1 - 0.11 11.8 1.5 0.19 11.0 1.5 1.3 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 KEY68284.1 - 0.12 11.9 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase COesterase PF00135.28 KEY68285.1 - 3.8e-84 283.4 0.0 1.2e-72 245.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY68285.1 - 2e-06 27.9 0.1 1.4e-05 25.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold CRAL_TRIO PF00650.20 KEY68288.1 - 7.2e-24 84.3 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY68288.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Lactonase PF10282.9 KEY68289.1 - 7.4e-85 285.2 0.0 9.7e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CDC45 PF02724.14 KEY68296.1 - 0.011 14.1 0.1 0.015 13.6 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ADH_N PF08240.12 KEY68299.1 - 1.9e-07 30.9 0.0 8.3e-07 28.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY68299.1 - 9.4e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68299.1 - 0.09 13.8 0.0 0.23 12.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ank_2 PF12796.7 KEY68300.1 - 6.3e-14 52.3 1.3 4.8e-06 27.1 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68300.1 - 9.8e-11 42.0 1.3 0.04 14.5 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY68300.1 - 1e-10 41.7 3.5 0.0065 16.8 0.0 4.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68300.1 - 1.5e-09 37.3 1.2 0.011 16.2 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KEY68300.1 - 1.2e-07 31.9 6.9 0.00024 21.4 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Transp_cyt_pur PF02133.15 KEY68302.1 - 3e-98 329.5 39.4 3.4e-98 329.3 39.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 KEY68303.1 - 1.3e-37 129.1 0.9 1.8e-37 128.7 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68303.1 - 2.3e-27 96.1 0.5 2.9e-27 95.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68303.1 - 1.4e-16 61.0 0.1 2e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY68303.1 - 2.4e-06 26.9 0.1 3.3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KEY68303.1 - 0.00048 20.2 0.0 0.0077 16.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KEY68303.1 - 0.0065 16.0 0.1 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY68303.1 - 0.02 14.0 0.2 0.031 13.4 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KEY68303.1 - 0.027 15.1 0.8 0.067 13.8 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_WecB PF03808.13 KEY68303.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 2-Hacid_dh_C PF02826.19 KEY68303.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM53 PF16760.5 KEY68304.1 - 0.058 14.0 0.2 0.39 11.3 0.2 2.2 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) p450 PF00067.22 KEY68305.1 - 3.8e-39 134.7 0.0 4.8e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SMP PF04927.12 KEY68306.1 - 5.3e-05 23.6 3.8 5.3e-05 23.6 3.8 1.6 1 1 1 2 2 2 1 Seed maturation protein SNARE PF05739.19 KEY68307.1 - 0.29 11.1 3.1 0.5 10.4 3.1 1.3 1 0 0 1 1 1 0 SNARE domain JSRP PF15312.6 KEY68307.1 - 0.83 9.6 3.2 17 5.4 0.1 2.5 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Tmemb_55A PF09788.9 KEY68307.1 - 6.2 5.8 5.6 16 4.5 1.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A Ras PF00071.22 KEY68308.1 - 4.3e-38 130.5 0.0 3.3e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY68308.1 - 8.9e-10 38.8 0.0 5e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY68308.1 - 0.00012 21.6 0.0 0.0014 18.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEY68308.1 - 0.00014 21.8 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 KEY68308.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KEY68308.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY68308.1 - 0.13 12.6 0.1 1.5 9.1 0.0 2.4 2 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 KEY68310.1 - 6.4e-15 54.7 0.0 1.1e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KEY68310.1 - 0.12 12.2 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Isochorismatase PF00857.20 KEY68311.1 - 3e-13 50.3 0.0 5.9e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF1100 PF06500.11 KEY68312.1 - 0.12 11.1 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) YacG PF03884.14 KEY68312.1 - 0.12 12.1 3.8 0.24 11.1 1.6 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-C6H2 PF15801.5 KEY68312.1 - 3.1 8.2 20.0 0.54 10.6 0.7 3.3 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Zn_clus PF00172.18 KEY68313.1 - 0.0016 18.5 10.9 0.0029 17.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3b10 PF07189.11 KEY68314.1 - 1.6e-38 130.6 0.0 1.9e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KEY68315.1 - 7.3e-68 228.4 0.0 1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 MAGE family DNA_pol_phi PF04931.13 KEY68315.1 - 2.2 6.3 9.5 5.3 5.0 9.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 KEY68315.1 - 9.3 5.2 10.7 16 4.4 10.7 1.3 1 0 0 1 1 1 0 Pes-10 SLS PF14611.6 KEY68316.1 - 1.4e-26 93.7 1.5 1.8e-26 93.3 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KEY68317.1 - 2.2e-55 187.2 0.0 3.2e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEY68317.1 - 7.2e-41 139.0 0.0 1.5e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEY68317.1 - 9.4e-15 54.8 1.2 1.9e-14 53.8 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY68317.1 - 0.00068 19.7 0.1 0.018 15.1 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KEY68317.1 - 0.05 13.5 0.2 0.16 11.9 0.2 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PDZ PF00595.24 KEY68317.1 - 0.15 12.5 0.4 0.93 9.9 0.0 2.5 2 0 0 2 2 2 0 PDZ domain MFS_1 PF07690.16 KEY68318.1 - 1e-39 136.5 36.2 4.3e-37 127.9 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68318.1 - 7.8e-09 34.9 3.7 7.8e-09 34.9 3.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 KEY68319.1 - 4.8e-44 150.9 0.0 6.8e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Yae1_N PF09811.9 KEY68320.1 - 5.9e-14 51.5 0.8 1e-13 50.7 0.8 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.9 KEY68320.1 - 0.073 13.5 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 CENP-O PF09496.10 KEY68322.1 - 1.8e-66 224.2 0.0 3.3e-66 223.3 0.0 1.4 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component BDV_P24 PF06595.11 KEY68322.1 - 0.0055 16.6 0.4 0.34 10.8 0.1 2.2 2 0 0 2 2 2 2 Borna disease virus P24 protein Acatn PF13000.7 KEY68323.1 - 2.2e-160 534.8 16.4 8e-82 275.5 7.1 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DFP PF04127.15 KEY68324.1 - 2.3e-12 47.2 0.0 1.4e-05 25.0 0.0 3.1 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 KEY68325.1 - 6.1e-37 127.4 70.9 1.2e-34 119.8 45.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68325.1 - 6.9e-07 28.5 40.4 2.2e-06 26.8 16.1 3.1 2 2 0 2 2 2 2 Sugar (and other) transporter Wbp11 PF09429.10 KEY68326.1 - 5.4e-20 71.6 16.5 5.4e-20 71.6 16.5 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 KEY68326.1 - 0.039 13.2 2.7 0.059 12.7 2.7 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein GATA PF00320.27 KEY68327.1 - 1.6e-16 59.6 2.3 3.6e-16 58.5 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KEY68327.1 - 2.3e-10 40.1 0.4 4.3e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pkinase PF00069.25 KEY68328.1 - 4.8e-61 206.4 0.0 3.9e-60 203.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68328.1 - 5.3e-29 101.3 0.4 2e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KEY68328.1 - 0.00081 20.0 3.9 0.001 19.7 1.4 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 KEY68328.1 - 0.0033 17.4 2.1 0.2 11.5 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY68328.1 - 0.011 15.1 0.2 0.034 13.5 0.0 1.8 3 0 0 3 3 3 0 Kinase-like Haspin_kinase PF12330.8 KEY68328.1 - 0.022 13.7 0.0 0.045 12.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KEY68328.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Regnase_1_C PF18561.1 KEY68329.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Bax1-I PF01027.20 KEY68329.1 - 0.037 13.9 0.7 0.037 13.9 0.7 1.6 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF3499 PF12005.8 KEY68329.1 - 0.15 12.6 0.0 0.61 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) CRCB PF02537.15 KEY68329.1 - 0.21 11.9 2.4 0.32 11.3 1.1 1.9 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Defensin_propep PF00879.18 KEY68329.1 - 0.28 11.5 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Defensin propeptide Pyrid_oxidase_2 PF13883.6 KEY68330.1 - 1.3e-41 142.4 0.0 1.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase APH PF01636.23 KEY68331.1 - 5.1e-17 62.6 0.0 9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Med12 PF09497.10 KEY68332.1 - 3.9e-27 94.3 0.8 1e-26 93.0 0.3 2.0 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 RhoGAP PF00620.27 KEY68333.1 - 4.5e-48 162.9 0.0 1e-47 161.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KEY68333.1 - 3.8e-11 43.1 0.1 3.8e-11 43.1 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5321 PF17254.2 KEY68333.1 - 0.18 11.2 0.8 0.33 10.4 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) DUF4407 PF14362.6 KEY68333.1 - 0.78 9.0 4.7 1.3 8.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KEY68333.1 - 0.98 9.5 10.0 0.21 11.6 1.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein OmpH PF03938.14 KEY68333.1 - 1.7 9.0 11.7 0.4 11.0 8.1 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ERM PF00769.19 KEY68333.1 - 2.3 8.0 14.8 3.8 7.3 14.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FeS_assembly_P PF01883.19 KEY68334.1 - 4.2e-08 33.2 0.1 3.1e-07 30.5 0.1 2.2 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 KEY68335.1 - 4.4e-44 150.4 0.0 6.8e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KEY68335.1 - 9.7e-35 119.8 7.2 2.1e-34 118.7 7.2 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KEY68335.1 - 1.7e-23 82.6 0.0 5.1e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KEY68335.1 - 1.4e-18 66.7 0.0 3.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY68335.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEY68335.1 - 1.5e-07 31.4 0.1 7.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KEY68335.1 - 0.00011 22.3 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KEY68335.1 - 0.037 13.5 0.1 0.16 11.4 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.23 KEY68336.1 - 7e-94 314.0 0.7 2e-93 312.5 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY68336.1 - 1.2e-47 160.6 0.7 3.3e-46 155.9 0.3 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEY68336.1 - 4.6e-07 29.7 1.8 2.8e-05 23.8 0.9 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY68336.1 - 0.00041 20.3 0.1 6.3 6.8 0.0 3.5 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KEY68336.1 - 0.027 14.3 0.8 3.4 7.6 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KEY68336.1 - 0.027 13.2 0.1 0.21 10.2 0.0 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ATXN-1_C PF12547.8 KEY68336.1 - 0.58 10.5 4.3 20 5.6 0.1 2.9 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator Sin3a_C PF16879.5 KEY68337.1 - 2.2e-74 250.7 2.1 5.6e-74 249.4 0.9 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 KEY68337.1 - 1.4e-42 143.6 7.2 9.4e-18 64.1 0.0 4.9 4 1 1 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KEY68337.1 - 6.2e-39 132.0 0.0 1.7e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor DUF2749 PF10907.8 KEY68337.1 - 0.1 12.8 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) TSP_NTD PF17804.1 KEY68337.1 - 3.1 8.0 9.7 0.36 11.1 0.3 3.1 4 0 0 4 4 4 0 Tail specific protease N-terminal domain Peptidase_M1_N PF17900.1 KEY68338.1 - 0.0021 18.3 0.1 0.19 11.9 0.0 3.0 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KEY68338.1 - 0.013 15.9 0.2 1.8 9.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats Peptidase_M1 PF01433.20 KEY68338.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M1 domain SAS4 PF15460.6 KEY68339.1 - 4.9e-31 106.8 1.2 4.9e-31 106.8 1.2 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PX PF00787.24 KEY68340.1 - 5.2e-21 74.7 0.0 6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.27 KEY68342.1 - 7.1e-05 22.3 0.1 0.00018 21.0 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cadherin_C PF01049.17 KEY68342.1 - 0.0073 16.7 0.2 0.027 14.8 0.2 2.0 1 0 0 1 1 1 1 Cadherin cytoplasmic region DUF4820 PF16091.5 KEY68342.1 - 8.8 5.6 9.3 4.8 6.5 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PQ-loop PF04193.14 KEY68343.1 - 2.2e-23 81.8 6.0 4.5e-14 51.9 1.8 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF3240 PF11582.8 KEY68343.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) ADH_N PF08240.12 KEY68344.1 - 5.6e-09 35.8 2.6 7.6e-09 35.4 0.2 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY68344.1 - 2.4e-06 28.7 0.0 4.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.11 KEY68344.1 - 0.18 11.5 0.4 0.42 10.3 0.4 1.5 1 0 0 1 1 1 0 Cupin domain zf-RING_2 PF13639.6 KEY68345.1 - 1.5e-08 34.8 5.5 1.5e-08 34.8 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 KEY68345.1 - 1.9e-06 27.8 0.8 1.9e-06 27.8 0.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEY68345.1 - 9.3e-06 25.8 4.0 9.3e-06 25.8 4.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain SWIM PF04434.17 KEY68345.1 - 8.8e-05 22.1 0.6 0.00017 21.2 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 KEY68345.1 - 0.00025 20.9 3.4 0.0015 18.4 1.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KEY68345.1 - 0.00057 19.7 3.7 0.00057 19.7 3.7 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KEY68345.1 - 0.00064 19.6 3.2 0.0015 18.4 3.2 1.7 1 1 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.6 KEY68345.1 - 0.0053 16.5 5.1 0.013 15.2 5.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KEY68345.1 - 0.0053 16.9 5.5 0.0053 16.9 5.5 2.2 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 KEY68345.1 - 0.016 15.1 4.0 0.016 15.1 4.0 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY68345.1 - 0.019 14.9 3.4 0.019 14.9 3.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY68345.1 - 0.023 14.7 5.5 0.023 14.7 5.5 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY68345.1 - 0.028 14.3 2.7 0.09 12.7 2.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KEY68345.1 - 0.054 13.6 5.1 0.15 12.2 5.1 1.8 1 0 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.14 KEY68345.1 - 0.058 13.2 1.3 0.92 9.4 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-UDP PF14569.6 KEY68345.1 - 0.09 12.9 0.9 0.26 11.4 0.9 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 KEY68345.1 - 0.12 12.5 3.0 0.44 10.7 3.0 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 KEY68345.1 - 0.15 12.3 3.5 12 6.3 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING-like PF08746.11 KEY68345.1 - 1.3 9.4 8.1 0.12 12.8 1.8 2.5 3 0 0 3 3 2 0 RING-like domain Prok-RING_4 PF14447.6 KEY68345.1 - 8.5 6.3 11.2 4.3 7.3 0.8 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Rad4 PF03835.15 KEY68346.1 - 2e-15 56.7 2.9 4.1e-15 55.7 2.9 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KEY68346.1 - 1.3e-11 45.0 2.5 2.4e-11 44.1 2.5 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily NAPRTase PF04095.16 KEY68347.1 - 5.8e-59 199.6 0.3 7e-32 110.9 0.2 3.0 3 0 0 3 3 3 3 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KEY68347.1 - 3.2e-35 121.2 0.1 5.5e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 KEY68348.1 - 5.2e-07 30.3 9.9 1.5 9.8 0.0 7.6 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY68348.1 - 6.8e-06 26.3 0.9 0.015 15.6 0.0 5.5 5 1 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEY68348.1 - 1.4e-05 24.8 3.0 0.029 14.0 0.1 3.5 3 1 1 4 4 4 2 PQQ-like domain PQQ PF01011.21 KEY68348.1 - 0.0004 20.2 0.1 0.0051 16.7 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KEY68348.1 - 0.0011 18.1 0.4 0.31 9.9 0.0 3.4 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 KEY68348.1 - 0.097 12.4 0.5 4.2 7.0 0.1 2.8 3 1 0 3 3 3 0 TUP1-like enhancer of split VD10_N PF08476.10 KEY68348.1 - 0.39 10.4 1.4 0.92 9.2 1.4 1.6 1 0 0 1 1 1 0 Viral D10 N-terminal MFS_1 PF07690.16 KEY68350.1 - 1.3e-26 93.4 64.1 1.8e-17 63.3 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY68350.1 - 3.6e-05 22.5 17.5 3.6e-05 22.5 17.5 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein NIBRIN_BRCT_II PF16508.5 KEY68351.1 - 1.2e-37 128.9 0.0 5.5e-37 126.7 0.0 2.1 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KEY68351.1 - 1.7e-09 37.9 0.0 3.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KEY68351.1 - 0.0017 18.2 0.3 0.0078 16.1 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Cyt-b5 PF00173.28 KEY68352.1 - 2.1e-15 56.6 0.0 2.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ-X PF14308.6 KEY68354.1 - 2.1e-79 265.9 0.5 2.1e-79 265.9 0.5 2.7 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KEY68354.1 - 6.1e-26 90.3 0.9 1.4e-25 89.2 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain SQS_PSY PF00494.19 KEY68355.1 - 1.7e-38 132.6 0.0 2.3e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_S8 PF00082.22 KEY68356.1 - 2e-32 112.7 19.0 3.3e-32 112.0 19.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY68356.1 - 0.004 17.8 0.1 0.0075 16.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 UDP-g_GGTase PF06427.11 KEY68356.1 - 0.093 12.9 0.1 0.45 10.6 0.0 2.1 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase Arylsulfotran_2 PF14269.6 KEY68357.1 - 9.7e-58 195.9 0.2 1.7e-57 195.1 0.2 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEY68357.1 - 2.4e-18 66.2 0.0 3.9e-17 62.2 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ada_Zn_binding PF02805.16 KEY68358.1 - 2.8e-30 104.2 4.5 5.1e-30 103.3 4.5 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 KEY68358.1 - 6.2e-08 32.8 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KEY68358.1 - 1.6e-07 31.3 0.0 1.3e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family UPF0175 PF03683.13 KEY68358.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Abhydrolase_6 PF12697.7 KEY68359.1 - 0.002 18.8 16.2 0.003 18.2 10.8 2.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Translin PF01997.16 KEY68360.1 - 1.9e-62 210.9 0.0 2.2e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 KEY68360.1 - 0.032 14.9 0.6 0.48 11.1 0.0 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ThiD2 PF17792.1 KEY68360.1 - 0.066 13.7 0.4 0.28 11.7 0.0 2.0 2 1 0 2 2 2 0 ThiD2 family BshC PF10079.9 KEY68360.1 - 0.14 10.9 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Mannosyl_trans PF05007.13 KEY68361.1 - 1.8e-79 267.3 11.1 2.3e-79 266.9 11.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KEY68361.1 - 1.5e-09 37.4 12.2 6.5e-09 35.3 12.2 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KEY68361.1 - 0.0027 17.5 21.3 0.0027 17.5 21.3 2.6 1 1 0 2 2 2 1 Glycosyltransferase family 87 Fungal_trans PF04082.18 KEY68362.1 - 1.2e-11 44.2 1.0 2.3e-11 43.3 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68362.1 - 4.1e-08 33.2 11.8 7.5e-08 32.4 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KEY68362.1 - 0.0003 20.6 0.3 0.0015 18.4 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY68362.1 - 0.045 13.7 0.8 1.5 8.8 0.2 2.7 2 0 0 2 2 2 0 F-box domain ZZ PF00569.17 KEY68364.1 - 1.4e-09 37.6 7.5 2.2e-09 36.9 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KEY68364.1 - 5.3e-08 31.9 6.4 0.00086 18.7 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KEY68364.1 - 5.2e-07 29.1 5.6 0.00096 18.9 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KEY68364.1 - 1.6e-06 28.4 3.2 0.00013 22.4 2.9 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KEY68364.1 - 0.0086 15.5 3.6 2.4 7.8 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEY68364.1 - 0.021 14.7 5.8 2.3 8.1 0.7 3.3 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_4 PF12763.7 KEY68364.1 - 0.048 13.6 0.1 0.86 9.6 0.0 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand C1_2 PF03107.16 KEY68364.1 - 0.098 13.0 10.4 0.19 12.0 10.4 1.4 1 0 0 1 1 1 0 C1 domain HIG_1_N PF04588.13 KEY68365.1 - 1.2e-23 83.0 0.8 2.4e-23 82.1 0.8 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PDDEXK_2 PF12784.7 KEY68365.1 - 0.089 12.3 4.2 0.13 11.7 4.2 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase TLD PF07534.16 KEY68366.1 - 2.9e-29 102.1 0.0 5.3e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 KEY68366.1 - 3.2e-12 47.3 0.9 9.2e-12 45.8 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function Nop14 PF04147.12 KEY68367.1 - 1.5 6.9 31.7 2.3 6.3 31.7 1.3 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_1 PF00561.20 KEY68369.1 - 5.5e-10 39.3 0.2 8.5e-10 38.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY68369.1 - 6.8e-10 38.6 0.5 1.7e-09 37.3 0.5 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY68369.1 - 8.1e-09 36.4 0.8 8.1e-09 36.4 0.8 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEY68369.1 - 1.4e-07 31.6 0.2 2.2e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY68369.1 - 0.00016 21.3 0.2 0.00046 19.7 0.0 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEY68369.1 - 0.0037 16.9 0.2 0.0061 16.2 0.2 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 KEY68369.1 - 0.027 13.4 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) NMT_C PF02799.15 KEY68370.1 - 2.6e-82 275.4 0.0 3.7e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KEY68370.1 - 2.4e-71 238.8 0.1 8.4e-71 237.0 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KEY68370.1 - 1.8e-06 28.0 0.0 0.0001 22.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY68370.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Abhydrolase_1 PF00561.20 KEY68371.1 - 8e-14 51.9 0.0 2.8e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY68371.1 - 7.7e-13 48.3 0.0 7.2e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY68371.1 - 4.6e-09 37.2 0.0 6.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KEY68371.1 - 0.00021 20.8 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KEY68371.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 KEY68371.1 - 0.01 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 KEY68371.1 - 0.021 14.7 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 KEY68371.1 - 0.033 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DLH PF01738.18 KEY68371.1 - 0.055 13.0 0.0 9.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1100 PF06500.11 KEY68371.1 - 0.096 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.16 KEY68371.1 - 0.12 12.1 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Stealth_CR3 PF17102.5 KEY68371.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 PGAP1 PF07819.13 KEY68371.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ribophorin_II PF05817.14 KEY68372.1 - 1.4e-28 99.9 0.0 1.6e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Acetyltransf_2 PF00797.17 KEY68373.1 - 3.5e-33 115.4 0.0 5.1e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KEY68373.1 - 0.14 12.7 0.3 0.58 10.6 0.0 2.2 3 0 0 3 3 3 0 Transglutaminase-like superfamily Peptidase_M28 PF04389.17 KEY68374.1 - 1.7e-34 119.3 0.0 2.1e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 KEY68376.1 - 5.6e-16 59.1 0.3 5.6e-16 59.1 0.3 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Bromodomain PF00439.25 KEY68380.1 - 9.4e-25 86.5 1.8 1.6e-24 85.8 0.5 2.0 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 KEY68380.1 - 6.8e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY68380.1 - 5.2e-07 29.7 0.2 1.6e-06 28.0 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY68380.1 - 0.00032 21.0 0.4 0.00064 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY68380.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Rad1 PF02144.16 KEY68381.1 - 9.8e-62 208.5 0.0 1.5e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KEY68381.1 - 8e-09 35.7 3.6 2.7e-08 34.0 3.6 2.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 ANAPC_CDC26 PF10471.9 KEY68384.1 - 1e-14 55.1 3.1 1.2e-14 54.8 3.1 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Metallophos PF00149.28 KEY68385.1 - 1.6e-08 35.3 5.4 6.7e-08 33.3 5.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF993 PF06187.11 KEY68385.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) SRP_SPB PF02978.19 KEY68386.1 - 0.15 12.7 0.6 0.44 11.2 0.6 1.7 1 0 0 1 1 1 0 Signal peptide binding domain IF4E PF01652.18 KEY68388.1 - 2.6e-53 180.1 0.3 3.3e-53 179.7 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 KEY68389.1 - 2.4e-66 224.1 0.0 4.8e-62 209.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEY68389.1 - 4.5e-12 46.8 0.0 1.7e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 KEY68390.1 - 5.7e-30 103.4 1.6 8.1e-30 102.9 1.6 1.2 1 0 0 1 1 1 1 BolA-like protein TEX15 PF15326.6 KEY68390.1 - 0.24 11.1 2.6 0.13 11.9 0.3 1.7 1 1 1 2 2 2 0 Testis expressed sequence 15 PIP5K PF01504.18 KEY68392.1 - 2e-31 109.2 0.0 6.7e-23 81.3 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KEY68392.1 - 4.9e-27 94.7 0.0 8.6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KEY68392.1 - 4.8e-13 49.0 9.7 1.1e-12 47.8 9.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger MMM1 PF10296.9 KEY68392.1 - 1.9e-05 23.9 0.0 5.8e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 VPS28 PF03997.12 KEY68393.1 - 2.1e-65 220.0 0.0 2.5e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 KEY68394.1 - 3.1e-126 420.6 0.0 5.3e-126 419.9 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KEY68394.1 - 4.2e-05 22.0 0.9 4.2e-05 22.0 0.9 3.5 2 2 1 3 3 3 1 Nop14-like family Cep57_CLD_2 PF14197.6 KEY68395.1 - 7.1e-30 102.9 66.4 2.6e-15 56.2 5.0 7.0 4 2 3 7 7 7 3 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 KEY68395.1 - 4.2e-29 100.8 0.3 4.2e-29 100.8 0.3 5.9 7 1 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 KASH_CCD PF14662.6 KEY68395.1 - 3.1e-06 27.1 70.6 0.013 15.4 24.1 5.8 3 1 1 5 5 5 3 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KEY68395.1 - 0.01 16.7 9.0 0.01 16.7 9.0 7.3 4 2 2 7 7 7 0 cGMP-dependent protein kinase interacting domain ArAE_2 PF10334.9 KEY68395.1 - 0.1 12.4 6.2 0.41 10.4 0.7 2.9 1 1 2 3 3 3 0 Aromatic acid exporter family member 2 ZapB PF06005.12 KEY68395.1 - 0.43 11.0 72.3 0.11 12.9 7.9 8.6 3 3 3 6 6 6 0 Cell division protein ZapB HALZ PF02183.18 KEY68395.1 - 5.2 7.4 57.9 0.22 11.8 4.0 10.0 5 1 4 10 10 10 0 Homeobox associated leucine zipper Sec34 PF04136.15 KEY68395.1 - 9.2 6.1 36.3 3.4 7.5 6.0 5.5 2 1 1 4 4 4 0 Sec34-like family Glyco_hydro_76 PF03663.14 KEY68396.1 - 1.6e-17 64.1 1.2 1.2e-16 61.2 0.8 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 PALP PF00291.25 KEY68397.1 - 6.6e-76 255.5 0.4 9.7e-76 255.0 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KEY68397.1 - 7.7e-38 128.2 0.0 1.5e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase cNMPbd_u2 PF16643.5 KEY68399.1 - 1.1e-34 120.2 14.9 1.1e-34 120.2 14.9 2.0 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KEY68399.1 - 1.7e-34 117.7 0.0 6.6e-20 71.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box-like PF12937.7 KEY68399.1 - 1.6e-05 24.7 0.4 5.5e-05 23.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY68399.1 - 6.1e-05 22.8 0.6 6.1e-05 22.8 0.6 3.4 4 0 0 4 4 4 1 F-box domain LRR_6 PF13516.6 KEY68399.1 - 0.0004 20.2 0.4 0.98 9.6 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 KEY68399.1 - 0.0073 16.7 0.0 0.28 11.6 0.0 3.2 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) HIT PF01230.23 KEY68399.1 - 0.085 13.6 0.1 0.24 12.1 0.1 1.7 1 0 0 1 1 1 0 HIT domain LRR_1 PF00560.33 KEY68399.1 - 0.11 13.2 3.3 21 6.2 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat Bax1-I PF01027.20 KEY68400.1 - 6.4e-32 111.1 9.4 9.4e-32 110.5 9.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.21 KEY68401.1 - 6.7e-55 185.5 0.0 8.1e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sugar_tr PF00083.24 KEY68402.1 - 1.5e-85 287.8 24.0 1.8e-85 287.5 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68402.1 - 2e-15 56.6 44.6 2.1e-14 53.3 19.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KEY68403.1 - 3.2e-27 96.1 0.1 3.5e-27 95.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 KEY68404.1 - 4.1e-23 81.8 3.1 6e-23 81.2 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68404.1 - 3.7e-09 36.6 9.2 6.2e-09 35.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKcGMP_CC PF16808.5 KEY68404.1 - 0.082 12.8 1.4 0.16 11.8 1.4 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MIP PF00230.20 KEY68405.1 - 7.2e-45 153.4 18.2 9.4e-45 153.1 18.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein 2-Hacid_dh_C PF02826.19 KEY68406.1 - 4.6e-47 159.7 0.1 2.8e-46 157.1 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KEY68406.1 - 1.3e-34 119.4 0.4 2.3e-34 118.6 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68406.1 - 9.9e-29 100.5 0.4 1.8e-28 99.7 0.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68406.1 - 6.2e-09 36.0 3.6 1.1e-08 35.2 0.5 2.7 2 2 0 2 2 2 1 KR domain 2-Hacid_dh PF00389.30 KEY68406.1 - 4.9e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEY68406.1 - 0.0025 18.0 1.3 0.019 15.1 0.1 3.0 3 1 1 4 4 4 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 KEY68406.1 - 0.12 11.3 0.1 1 8.3 0.1 2.3 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 KEY68407.1 - 2e-33 115.3 0.0 3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY68407.1 - 1.8e-22 79.8 0.0 3.6e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY68407.1 - 9.6e-09 34.9 0.0 2.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY68407.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Mannosidase_ig PF17786.1 KEY68408.1 - 8.5e-16 58.3 1.5 1.5e-15 57.6 0.3 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KEY68408.1 - 5.3e-12 46.4 0.4 3.3e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KEY68408.1 - 3.9e-06 26.5 0.1 1.3e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KEY68408.1 - 0.00023 21.1 0.0 0.00068 19.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 KEY68408.1 - 0.032 14.4 0.8 0.53 10.5 0.1 2.6 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Peptidase_S8 PF00082.22 KEY68409.1 - 3.8e-31 108.5 15.8 4.9e-31 108.1 15.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY68409.1 - 3.4e-16 59.7 0.0 6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Malic_M PF03949.15 KEY68410.1 - 2.3e-87 292.5 0.0 3.4e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEY68410.1 - 8.1e-65 218.0 0.0 1.6e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF5427 PF10310.9 KEY68411.1 - 1.9e-175 584.3 2.5 2.3e-175 584.1 2.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) SARAF PF06682.12 KEY68411.1 - 0.51 9.9 6.7 1.1 8.9 6.7 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GatB_Yqey PF02637.18 KEY68412.1 - 0.26 11.2 3.4 0.81 9.6 3.4 1.8 1 0 0 1 1 1 0 GatB domain DUF637 PF04830.13 KEY68412.1 - 2.4 7.9 5.2 1.6 8.5 1.2 2.2 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) Ribosomal_L14 PF00238.19 KEY68413.1 - 1.1e-32 112.6 0.0 1.3e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Methyltransf_24 PF13578.6 KEY68414.1 - 3.9e-11 43.9 0.0 7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEY68414.1 - 3.4e-10 39.5 0.0 4.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Fungal_trans PF04082.18 KEY68415.1 - 1.1e-17 64.0 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68415.1 - 1.9e-09 37.5 11.0 3.2e-09 36.7 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KEY68416.1 - 2.9e-08 33.8 0.0 8.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KEY68417.1 - 1.3e-34 119.8 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68417.1 - 5.1e-17 62.0 0.0 1.1e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY68417.1 - 0.018 15.0 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY68417.1 - 0.023 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 KEY68417.1 - 0.048 13.8 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Cactin_mid PF10312.9 KEY68419.1 - 6.6e-63 212.0 3.9 9.6e-63 211.5 3.9 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KEY68419.1 - 2.7e-58 195.4 5.1 4.4e-58 194.7 5.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KEY68419.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Forkhead PF00250.18 KEY68420.1 - 1.3e-20 73.4 0.1 2.7e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain XLF PF09302.11 KEY68421.1 - 4.9e-53 179.9 0.0 8.1e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAD_binding_7 PF03441.14 KEY68422.1 - 4.9e-83 277.6 0.0 1.1e-82 276.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KEY68422.1 - 1e-38 132.9 0.1 1.7e-38 132.2 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KEY68422.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family Ribosomal_S21e PF01249.18 KEY68423.1 - 5.4e-41 138.6 0.1 6e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 KEY68423.1 - 0.045 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Slx4 PF09494.10 KEY68424.1 - 1.4e-24 85.8 0.0 2.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Egh16-like PF11327.8 KEY68425.1 - 3.1e-55 187.5 7.0 3.7e-55 187.2 7.0 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 KEY68425.1 - 0.039 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF3810 PF12725.7 KEY68427.1 - 0.81 9.0 0.0 0.81 9.0 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) Sulfate_transp PF00916.20 KEY68428.1 - 3.8e-90 302.4 17.2 6.8e-90 301.6 17.2 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEY68428.1 - 2.7e-12 46.4 0.0 7.6e-12 44.9 0.0 1.7 1 1 0 1 1 1 1 STAS domain Cupin_1 PF00190.22 KEY68429.1 - 1.3e-40 138.4 0.0 4.5e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KEY68429.1 - 5.9e-28 96.4 0.6 9.7e-14 50.8 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KEY68429.1 - 3.3e-09 36.3 0.0 0.0011 18.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KEY68429.1 - 1.7e-06 28.0 0.1 0.0014 18.6 0.1 3.2 1 1 2 3 3 3 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KEY68429.1 - 0.00042 20.2 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 KEY68429.1 - 0.0014 18.3 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 KEY68429.1 - 0.011 15.9 0.4 3 8.0 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.7 KEY68429.1 - 0.041 13.8 0.3 0.47 10.4 0.1 2.5 2 1 0 2 2 2 0 ChrR Cupin-like domain DUF1275 PF06912.11 KEY68430.1 - 3.5e-47 160.8 17.5 4.4e-47 160.5 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KEY68431.1 - 3.3e-29 101.9 34.1 4.8e-29 101.4 34.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68431.1 - 5.6e-09 35.4 16.6 1.8e-08 33.7 16.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter WTF PF03303.13 KEY68431.1 - 0.063 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 WTF protein DUF2208 PF09973.9 KEY68431.1 - 1.9 8.0 4.1 1.2 8.7 1.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pkinase PF00069.25 KEY68432.1 - 1.9e-74 250.4 0.0 3.1e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68432.1 - 8.9e-38 130.0 0.0 2.3e-37 128.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY68432.1 - 0.0002 20.8 0.5 0.56 9.5 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KEY68432.1 - 0.0079 15.0 0.2 0.024 13.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEY68432.1 - 0.066 13.1 0.0 0.32 10.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family JAB PF01398.21 KEY68434.1 - 1.1e-32 112.4 0.0 2.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KEY68434.1 - 9.6e-12 45.3 0.4 2.1e-11 44.2 0.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KEY68434.1 - 4.2e-07 29.8 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KEY68435.1 - 1.2e-83 281.2 0.0 1.9e-83 280.5 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.12 KEY68436.1 - 3e-97 326.0 0.0 3.7e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Mnd1 PF03962.15 KEY68436.1 - 0.0052 17.0 0.6 0.052 13.8 0.1 2.5 2 0 0 2 2 2 1 Mnd1 HTH domain RPA_C PF08784.11 KEY68436.1 - 0.023 15.3 0.0 1.4 9.6 0.0 3.0 3 0 0 3 3 3 0 Replication protein A C terminal Ribosomal_60s PF00428.19 KEY68436.1 - 0.78 10.4 3.9 2.5 8.8 0.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pro_isomerase PF00160.21 KEY68437.1 - 3e-44 151.1 0.4 3.5e-44 150.9 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KEY68438.1 - 3.9e-46 156.2 0.0 5.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KEY68438.1 - 0.0029 16.6 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 KEY68438.1 - 0.74 9.8 7.3 0.66 10.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) MARVEL PF01284.23 KEY68439.1 - 1.1e-06 28.7 13.9 2.5e-06 27.6 13.8 1.6 1 1 0 1 1 1 1 Membrane-associating domain ABA_GPCR PF12430.8 KEY68439.1 - 0.025 14.4 1.7 0.041 13.7 1.7 1.4 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor SMN PF06003.12 KEY68440.1 - 2.5 7.3 5.0 2.5 7.3 5.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Fungal_trans_2 PF11951.8 KEY68441.1 - 9e-51 172.9 0.2 1.3e-50 172.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68441.1 - 1.3e-06 28.5 7.2 2.1e-06 27.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.23 KEY68443.1 - 4.9e-07 30.4 4.6 6.9e-07 29.9 4.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Zip PF02535.22 KEY68444.1 - 1.6e-54 185.3 5.2 4.9e-54 183.8 5.2 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.22 KEY68444.1 - 0.08 13.0 6.4 0.086 12.9 0.0 3.1 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2749 PF10907.8 KEY68444.1 - 0.22 11.7 1.1 5.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) TPR_1 PF00515.28 KEY68445.1 - 1.8e-39 132.0 31.2 2.1e-07 30.5 0.9 9.5 9 1 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KEY68445.1 - 4.4e-39 132.2 17.4 3.2e-21 75.0 1.9 3.0 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 KEY68445.1 - 1.5e-29 99.7 33.6 7.2e-06 25.7 0.3 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KEY68445.1 - 1.4e-16 59.9 22.7 0.0023 17.6 3.2 7.7 5 2 3 8 8 8 6 TPR repeat TPR_12 PF13424.6 KEY68445.1 - 3e-14 53.1 15.2 4.2e-09 36.6 0.5 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY68445.1 - 2.6e-13 50.3 11.9 0.00026 21.4 0.1 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY68445.1 - 1.7e-12 47.0 5.6 2.2 9.3 0.0 8.1 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY68445.1 - 2.6e-11 44.0 9.0 0.00035 21.1 0.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEY68445.1 - 6.8e-11 41.8 8.9 0.73 10.3 0.1 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68445.1 - 5.1e-10 38.7 42.0 0.00034 20.6 0.2 9.0 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY68445.1 - 9.9e-09 34.6 3.6 0.034 14.2 0.3 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY68445.1 - 2e-08 33.8 5.7 0.011 15.5 0.1 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEY68445.1 - 1.1e-07 31.9 1.7 0.029 14.5 0.1 4.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEY68445.1 - 0.00067 20.1 13.6 1.5 9.6 0.1 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEY68445.1 - 0.0055 16.7 3.8 63 3.8 0.0 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat GerD PF17898.1 KEY68445.1 - 0.0056 16.6 10.4 0.046 13.7 2.7 3.5 3 0 0 3 3 3 2 Spore germination GerD central core domain SHNi-TPR PF10516.9 KEY68445.1 - 0.017 14.6 0.3 7 6.2 0.0 3.8 3 0 0 3 3 3 0 SHNi-TPR ANAPC3 PF12895.7 KEY68445.1 - 0.035 14.3 8.1 0.26 11.5 2.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_3_C PF01915.22 KEY68446.1 - 3.6e-55 187.1 0.0 9.9e-55 185.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY68446.1 - 4e-54 184.2 0.0 7.1e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY68446.1 - 2.1e-22 79.0 0.2 1.2e-21 76.6 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KEY68446.1 - 9.4e-06 25.5 0.0 8.5e-05 22.4 0.0 2.4 2 1 1 3 3 3 1 PA14 domain Ig_GlcNase PF18368.1 KEY68446.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain FMO-like PF00743.19 KEY68447.1 - 3.1e-12 45.7 0.0 7.7e-12 44.4 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEY68447.1 - 8.1e-11 41.7 0.0 4.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY68447.1 - 5.1e-10 39.4 0.0 1.1e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68447.1 - 4.1e-08 33.2 0.4 0.049 13.2 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY68447.1 - 1.2e-06 28.0 0.0 7.7e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY68447.1 - 6e-06 25.7 0.3 0.0018 17.6 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY68447.1 - 1.7e-05 24.2 0.0 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KEY68447.1 - 4.1e-05 22.9 0.0 0.0073 15.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY68447.1 - 0.00011 22.2 0.7 12 5.9 0.0 4.6 5 0 0 5 5 5 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEY68447.1 - 0.00049 20.6 0.1 0.67 10.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEY68447.1 - 0.0012 18.9 0.0 0.032 14.3 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KEY68447.1 - 0.0058 15.7 0.0 0.39 9.7 0.0 3.3 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KEY68447.1 - 0.016 14.6 0.0 0.073 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KEY68447.1 - 0.02 14.0 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEY68447.1 - 0.021 14.1 0.0 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KEY68447.1 - 0.028 13.5 0.0 0.57 9.2 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KEY68447.1 - 0.05 12.4 0.0 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase p450 PF00067.22 KEY68448.1 - 8e-46 156.7 0.0 1.1e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FUSC PF04632.12 KEY68449.1 - 0.02 13.5 0.6 0.027 13.0 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 KEY68449.1 - 0.073 11.9 0.4 0.16 10.8 0.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein LSM PF01423.22 KEY68450.1 - 2.8e-21 75.0 0.5 3.1e-21 74.8 0.5 1.0 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.20 KEY68451.1 - 5e-07 30.2 0.0 7.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Amino_oxidase PF01593.24 KEY68452.1 - 2e-60 205.4 0.0 2.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY68452.1 - 1e-08 35.2 0.1 4.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68452.1 - 0.00087 19.0 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY68452.1 - 0.029 13.6 0.2 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KEY68452.1 - 0.056 12.7 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEY68452.1 - 0.1 11.2 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KEY68452.1 - 0.12 11.6 0.0 0.75 9.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KEY68453.1 - 0.23 11.6 11.2 0.45 10.7 11.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3844 PF12955.7 KEY68454.1 - 1.7e-35 121.3 4.2 1.7e-35 121.3 4.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KEY68454.1 - 0.32 11.4 5.7 1.3 9.5 5.7 2.1 1 1 0 1 1 1 0 EGF-like domain HLH PF00010.26 KEY68456.1 - 4.4e-09 36.2 0.0 8.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 KEY68457.1 - 4.6e-49 166.5 0.0 5.4e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Bromodomain PF00439.25 KEY68458.1 - 1.1e-29 102.4 0.4 3.8e-14 52.5 0.1 2.5 2 0 0 2 2 2 2 Bromodomain CDC45 PF02724.14 KEY68458.1 - 0.32 9.2 9.0 0.54 8.5 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KEY68458.1 - 0.4 8.8 10.7 0.62 8.2 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KEY68458.1 - 2.3 8.2 5.9 5.3 7.1 5.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KEY68458.1 - 4 6.7 10.0 6 6.1 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 KEY68458.1 - 6.4 6.7 8.3 15 5.5 8.3 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2408 PF10303.9 KEY68460.1 - 0.079 13.5 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) tRNA-synt_2b PF00587.25 KEY68461.1 - 5e-35 121.1 0.1 7e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEY68461.1 - 2.2e-05 24.5 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain YscW PF09619.10 KEY68461.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) DUF4078 PF13300.6 KEY68461.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) IBN_N PF03810.19 KEY68462.1 - 7.3e-13 48.2 0.1 2.6e-12 46.5 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 KEY68462.1 - 0.00042 19.3 0.0 0.0034 16.2 0.0 2.1 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 KEY68462.1 - 0.00045 20.3 0.4 0.0067 16.5 0.0 3.0 2 1 1 3 3 3 1 Exportin 1-like protein SWI-SNF_Ssr4 PF08549.10 KEY68463.1 - 3.6e-289 961.5 1.8 4.1e-289 961.3 1.8 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 KEY68464.1 - 1.1e-128 428.7 0.0 1.4e-128 428.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEY68464.1 - 1.2e-50 171.8 0.0 1.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEY68464.1 - 0.064 13.5 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DNA_pol3_beta PF00712.19 KEY68464.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain PGK PF00162.19 KEY68464.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.22 KEY68465.1 - 6.4e-17 61.1 0.0 1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 KEY68465.1 - 0.0029 17.9 0.1 0.0085 16.4 0.1 1.8 1 0 0 1 1 1 1 Cytotoxic OB_RNB PF08206.11 KEY68465.1 - 0.14 11.9 0.4 0.27 11.0 0.4 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain TPT PF03151.16 KEY68466.1 - 3.6e-20 72.5 16.2 5.6e-20 71.9 16.2 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEY68466.1 - 9.5e-05 22.6 37.3 0.042 14.0 11.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KEY68466.1 - 0.05 12.8 20.4 0.0085 15.3 15.6 1.9 2 0 0 2 2 2 0 UAA transporter family Cation_ATPase_N PF00690.26 KEY68466.1 - 1.3 8.7 5.2 0.14 11.8 0.4 1.9 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Glyco_hydro_15 PF00723.21 KEY68467.1 - 4.6e-51 174.0 0.0 2.2e-46 158.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 NAM-associated PF14303.6 KEY68468.1 - 0.095 13.4 0.2 0.11 13.2 0.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HAD PF12710.7 KEY68469.1 - 1.7e-13 51.4 0.5 1.8e-12 48.0 0.2 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY68469.1 - 0.00045 20.6 0.1 0.0021 18.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEY68469.1 - 0.0041 17.2 2.2 0.22 11.6 2.2 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEY68469.1 - 0.045 13.5 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KEY68469.1 - 0.33 10.3 0.9 21 4.4 0.1 2.9 2 1 0 3 3 3 0 Putative Phosphatase TFIIF_beta_N PF17683.1 KEY68470.1 - 1.6e-31 109.8 0.3 4.7e-31 108.3 0.0 1.9 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KEY68470.1 - 1.9e-27 95.2 0.1 3.1e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Elongin_A PF06881.11 KEY68471.1 - 1.5e-29 102.6 1.7 2.8e-29 101.7 1.7 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Pox_Ag35 PF03286.14 KEY68471.1 - 5.3 6.8 11.9 0.11 12.2 4.5 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cation_ATPase_C PF00689.21 KEY68472.1 - 1.5e-41 142.1 4.8 1.5e-41 142.1 4.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEY68472.1 - 4.1e-33 114.4 0.5 4.1e-33 114.4 0.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEY68472.1 - 2.5e-22 80.2 0.3 1.1e-21 78.0 0.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY68472.1 - 1.4e-20 73.1 0.0 2.5e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEY68472.1 - 4.1e-08 32.8 4.3 4.9e-08 32.6 0.1 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY68472.1 - 0.00018 21.3 0.2 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Band_7 PF01145.25 KEY68473.1 - 3.1e-22 79.4 3.3 4.7e-22 78.9 3.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KEY68473.1 - 0.13 12.4 1.4 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Mediator complex subunit 2 Methyltransf_11 PF08241.12 KEY68474.1 - 9e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68474.1 - 9.7e-06 26.2 0.0 2.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY68474.1 - 0.021 15.6 0.0 0.062 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68474.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3484 PF11983.8 KEY68474.1 - 3.1 9.0 6.8 2.1 9.5 1.1 3.1 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch SUI1 PF01253.22 KEY68475.1 - 3e-18 66.1 0.5 3e-18 66.1 0.5 2.1 2 1 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 KEY68475.1 - 0.056 13.8 0.1 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) MscS_TM PF12794.7 KEY68475.1 - 1.4 7.7 2.7 2.1 7.1 2.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nbl1_Borealin_N PF10444.9 KEY68476.1 - 2.1e-17 62.5 0.7 3.4e-17 61.8 0.7 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Sgf11_N PF18519.1 KEY68476.1 - 0.011 15.3 0.4 0.063 12.8 0.1 2.2 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain VWA_2 PF13519.6 KEY68477.1 - 5.5e-27 94.5 0.4 1.5e-26 93.2 0.0 1.9 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KEY68477.1 - 1.6e-11 44.8 0.4 2.2e-11 44.3 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KEY68477.1 - 1.4e-09 38.1 0.1 2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KEY68477.1 - 0.0091 15.9 1.4 0.036 14.0 1.4 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif Sybindin PF04099.12 KEY68478.1 - 2.4e-53 179.9 0.0 2.8e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KEY68478.1 - 2e-07 31.2 0.0 2.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.16 KEY68479.1 - 5.5e-26 91.3 5.5 6.9e-26 91.0 5.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.6 KEY68479.1 - 0.012 15.8 1.2 0.016 15.4 0.3 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Mu-like_Pro PF10123.9 KEY68479.1 - 0.23 11.0 2.6 0.26 10.8 2.6 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein TMEM154 PF15102.6 KEY68480.1 - 0.0031 17.4 3.0 0.0075 16.2 2.4 1.9 1 1 0 1 1 1 1 TMEM154 protein family FAM176 PF14851.6 KEY68480.1 - 0.0042 16.7 0.2 0.11 12.1 0.2 2.2 2 0 0 2 2 2 1 FAM176 family EphA2_TM PF14575.6 KEY68480.1 - 0.011 16.6 0.0 0.026 15.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KEY68480.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orthoreo_P10 PF07204.11 KEY68480.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Conotoxin PF02950.17 KEY68480.1 - 1.6 9.8 0.0 1.6 9.8 0.0 3.0 2 1 1 3 3 3 0 Conotoxin CPL PF08144.11 KEY68481.1 - 5.8e-41 140.2 0.1 1.4e-38 132.5 0.0 3.9 4 1 0 4 4 4 1 CPL (NUC119) domain CTI PF06934.11 KEY68481.1 - 0.0021 16.7 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) RWD PF05773.22 KEY68482.1 - 5.6e-23 81.4 0.7 1.1e-22 80.5 0.7 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KEY68482.1 - 3.1e-06 27.6 7.3 6.5e-06 26.6 7.0 1.7 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 KEY68482.1 - 0.023 14.9 0.9 0.037 14.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) UQ_con PF00179.26 KEY68482.1 - 0.089 12.4 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme UNC-79 PF14776.6 KEY68482.1 - 0.14 10.8 0.2 0.2 10.4 0.2 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 TPR_12 PF13424.6 KEY68483.1 - 2.2e-16 59.9 0.0 1.2e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY68483.1 - 1.8e-14 53.2 2.6 0.018 15.8 0.1 5.2 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY68483.1 - 4.1e-14 51.5 0.9 9e-07 28.5 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68483.1 - 9.9e-13 47.2 0.0 3.7e-07 29.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY68483.1 - 4.3e-12 46.5 0.0 7.4e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY68483.1 - 1.5e-11 44.7 0.3 0.018 15.5 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY68483.1 - 9e-11 41.1 0.0 5.4e-06 26.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY68483.1 - 1.7e-08 33.9 0.2 0.00035 20.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY68483.1 - 1.2e-07 31.5 0.1 0.0034 16.8 0.1 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KEY68483.1 - 1.4e-06 28.0 2.0 0.19 11.6 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KEY68483.1 - 2.4e-06 27.2 0.8 0.0048 16.5 0.1 3.4 2 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KEY68483.1 - 5.9e-06 26.3 0.1 0.6 10.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEY68483.1 - 1.8e-05 25.1 0.6 0.13 12.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY68483.1 - 6e-05 23.2 0.0 5.1 7.4 0.0 4.4 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KEY68483.1 - 0.0046 17.5 6.7 0.49 11.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEY68483.1 - 0.011 15.3 0.0 1 9.1 0.0 3.2 4 0 0 4 4 4 0 TPR repeat Sel1 PF08238.12 KEY68483.1 - 0.055 14.2 0.0 2.4 8.9 0.0 2.9 2 0 0 2 2 2 0 Sel1 repeat RNA_pol_3_Rpc31 PF11705.8 KEY68483.1 - 0.45 10.7 7.3 0.84 9.8 7.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Lum_binding PF00677.17 KEY68484.1 - 2.3e-46 155.7 4.3 6e-23 80.7 2.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 KEY68485.1 - 3.1e-24 85.9 0.0 5.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Ish1 PF10281.9 KEY68485.1 - 0.0031 17.8 0.0 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein PGM_PMM_I PF02878.16 KEY68486.1 - 7.2e-18 64.6 0.5 1.7e-07 31.0 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KEY68486.1 - 2e-10 40.7 0.4 1.1e-09 38.3 0.2 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KEY68486.1 - 0.0052 17.0 0.1 0.022 15.0 0.1 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEY68486.1 - 0.01 16.4 0.3 0.43 11.2 0.3 3.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PrmA PF06325.13 KEY68487.1 - 1.6e-10 40.9 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KEY68487.1 - 7.7e-10 39.3 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68487.1 - 1.9e-08 34.3 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY68487.1 - 2.5e-07 31.2 0.0 5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KEY68487.1 - 4.3e-07 29.2 0.2 6.3e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KEY68487.1 - 3.3e-05 23.9 0.1 5.7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY68487.1 - 0.00035 20.5 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KEY68487.1 - 0.0029 17.5 0.2 0.0054 16.6 0.2 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 KEY68487.1 - 0.005 16.2 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KEY68487.1 - 0.0055 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY68487.1 - 0.0066 17.2 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEY68487.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.9 KEY68487.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 KEY68487.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Crust_neurohorm PF01147.17 KEY68489.1 - 0.023 14.5 4.2 0.023 14.5 4.2 2.0 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zinc_ribbon_12 PF11331.8 KEY68489.1 - 0.032 14.0 4.6 0.65 9.9 0.1 2.4 2 1 0 2 2 2 0 Probable zinc-ribbon domain LrgB PF04172.16 KEY68490.1 - 1.2e-55 188.4 9.4 1.2e-55 188.4 9.4 2.3 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KEY68490.1 - 8.1e-06 25.7 6.9 8.1e-06 25.7 6.9 3.3 3 0 0 3 3 3 1 LrgA family DUF373 PF04123.13 KEY68490.1 - 7.8 5.8 8.8 0.3 10.5 0.4 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF373) Linker_histone PF00538.19 KEY68492.1 - 1.2e-28 99.3 0.1 2.7e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Sec23_trunk PF04811.15 KEY68493.1 - 5.2e-50 170.3 0.0 1.2e-49 169.2 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEY68493.1 - 2.3e-25 88.4 0.0 4.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEY68493.1 - 8.2e-17 61.7 0.0 1.4e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEY68493.1 - 2e-15 56.5 4.3 4.2e-15 55.5 4.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KEY68493.1 - 4.4e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 KEY68494.1 - 8.1e-07 29.5 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sulfatase PF00884.23 KEY68495.1 - 2.2e-53 181.6 0.1 3e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEY68495.1 - 0.13 11.8 0.3 0.32 10.5 0.3 1.7 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KEY68495.1 - 0.27 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HAD_2 PF13419.6 KEY68496.1 - 5.5e-09 36.4 0.0 1.9e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY68496.1 - 0.00014 22.2 0.0 0.0011 19.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 2OG-Fe_Oxy_2 PF10014.9 KEY68497.1 - 6.2e-53 179.4 0.1 8.7e-53 179.0 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase Sporozoite_P67 PF05642.11 KEY68498.1 - 0.1 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_tran PF00005.27 KEY68499.1 - 1.9e-46 158.0 0.4 8.3e-25 87.9 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KEY68499.1 - 3e-32 112.4 25.4 1.5e-25 90.4 6.2 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY68499.1 - 1e-10 41.4 0.9 0.01 15.3 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY68499.1 - 1.6e-07 30.9 0.3 0.0086 15.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY68499.1 - 5.3e-06 26.4 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KEY68499.1 - 5.4e-06 26.4 1.3 0.0035 17.2 0.1 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KEY68499.1 - 9.4e-06 25.7 0.1 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY68499.1 - 1.6e-05 25.2 3.3 0.013 15.8 0.0 3.7 5 0 0 5 5 3 1 AAA domain AAA_25 PF13481.6 KEY68499.1 - 0.00051 19.7 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY68499.1 - 0.00062 20.2 0.0 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KEY68499.1 - 0.00093 18.8 0.3 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 KEY68499.1 - 0.001 19.5 0.0 0.064 13.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEY68499.1 - 0.0011 19.5 0.0 0.74 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEY68499.1 - 0.0023 18.3 0.1 0.84 10.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 KEY68499.1 - 0.0029 17.4 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KEY68499.1 - 0.003 16.8 0.0 0.084 12.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 KEY68499.1 - 0.0055 17.2 12.8 0.028 14.9 0.3 3.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KEY68499.1 - 0.0072 16.3 1.5 2.3 8.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) cobW PF02492.19 KEY68499.1 - 0.012 15.2 0.7 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEY68499.1 - 0.012 15.7 0.1 0.71 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KEY68499.1 - 0.015 14.4 0.2 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KEY68499.1 - 0.015 15.2 1.8 0.049 13.5 0.0 2.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KEY68499.1 - 0.016 15.0 1.0 0.76 9.5 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 KEY68499.1 - 0.02 14.6 2.4 0.34 10.6 0.1 2.5 3 0 0 3 3 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KEY68499.1 - 0.02 14.5 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KEY68499.1 - 0.022 13.9 0.0 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KEY68499.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 KEY68499.1 - 0.03 13.7 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KEY68499.1 - 0.036 13.3 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KEY68499.1 - 0.039 13.7 0.5 7.5 6.2 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein DEAD PF00270.29 KEY68499.1 - 0.051 13.3 0.4 1.1 8.9 0.4 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Med17 PF10156.9 KEY68499.1 - 0.068 11.9 1.6 0.11 11.2 1.6 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF87 PF01935.17 KEY68499.1 - 0.076 13.1 6.9 0.29 11.2 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 KEY68499.1 - 0.081 12.8 1.2 2.6 7.9 0.1 3.1 3 0 0 3 3 2 0 NACHT domain AAA_14 PF13173.6 KEY68499.1 - 0.1 12.6 0.1 1.2 9.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 KEY68499.1 - 0.12 12.1 0.1 3.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 KEY68499.1 - 0.12 11.1 0.5 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 KEY68499.1 - 0.31 11.0 1.0 4.9 7.0 0.1 2.5 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 KEY68499.1 - 0.5 10.4 7.2 0.41 10.7 0.1 2.6 3 0 0 3 3 2 0 Dynamin family Septin PF00735.18 KEY68499.1 - 9.2 5.4 8.2 31 3.7 0.1 3.1 3 0 0 3 3 3 0 Septin Aldolase_II PF00596.21 KEY68500.1 - 8.6e-43 146.4 0.1 1.2e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AMP-binding PF00501.28 KEY68501.1 - 1.9e-71 240.9 0.0 2.5e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY68501.1 - 1.3e-14 54.9 0.1 3.6e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PS-DH PF14765.6 KEY68502.1 - 1e-64 218.7 0.0 1.6e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY68502.1 - 3e-64 217.5 0.0 5.5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KEY68502.1 - 3.9e-57 193.7 0.0 9.3e-57 192.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY68502.1 - 2.1e-55 187.4 0.1 4.2e-55 186.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KEY68502.1 - 2.1e-34 118.1 0.0 4.8e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY68502.1 - 4.9e-22 78.5 0.0 1.1e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KEY68502.1 - 3.6e-17 63.7 0.0 1.1e-15 58.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KEY68502.1 - 1.2e-16 61.3 0.0 1.7e-14 54.3 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEY68502.1 - 2.7e-15 56.5 0.6 1.4e-14 54.2 0.0 2.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KEY68502.1 - 2.2e-11 43.9 0.0 6.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY68502.1 - 1.3e-08 35.4 0.0 7e-08 33.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68502.1 - 6.1e-08 32.6 0.0 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KEY68502.1 - 9e-08 31.8 1.9 3.6e-07 29.8 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KEY68502.1 - 1.2e-07 32.3 0.0 1.7e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 KEY68502.1 - 1.3e-05 25.0 0.3 4.2e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY68502.1 - 0.00024 21.4 0.0 0.00077 19.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEY68502.1 - 0.0039 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KEY68502.1 - 0.052 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CFEM PF05730.11 KEY68503.1 - 3e-10 40.0 9.6 6.3e-10 39.0 9.6 1.6 1 0 0 1 1 1 1 CFEM domain SPC25 PF06703.11 KEY68503.1 - 4.1 7.2 5.6 2.4 7.9 0.5 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) AATase PF07247.12 KEY68506.1 - 1.7e-08 33.5 0.0 4.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KEY68506.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KEY68506.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Glycos_transf_1 PF00534.20 KEY68506.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Zn_clus PF00172.18 KEY68507.1 - 2.3e-05 24.4 9.7 4.5e-05 23.5 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY68507.1 - 2.6e-05 23.2 0.1 3.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ANAPC4_WD40 PF12894.7 KEY68509.1 - 3.1e-12 46.6 0.8 2.3e-06 27.8 0.1 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY68509.1 - 2.9e-11 43.7 9.2 0.34 11.9 1.9 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Frtz PF11768.8 KEY68509.1 - 0.0012 17.3 0.0 0.0018 16.7 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Inv-AAD PF18785.1 KEY68510.1 - 3.1e-41 140.3 0.0 5.2e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KEY68510.1 - 1.7e-10 40.7 0.0 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ADH_zinc_N PF00107.26 KEY68511.1 - 1.1e-22 80.4 0.2 2.3e-22 79.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY68511.1 - 3.7e-19 68.6 1.7 7.5e-19 67.6 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KEY68511.1 - 0.035 13.5 2.4 0.059 12.8 2.4 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 KEY68511.1 - 0.054 13.7 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KEY68511.1 - 0.055 12.8 3.2 0.089 12.1 3.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KEY68511.1 - 0.15 11.5 1.7 2.3 7.7 0.8 2.6 2 1 1 3 3 3 0 short chain dehydrogenase Aldedh PF00171.22 KEY68512.1 - 2.2e-146 488.0 0.2 2.7e-146 487.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEY68512.1 - 0.00021 20.5 0.0 0.00041 19.5 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KEY68512.1 - 0.0061 16.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) MlaA PF04333.13 KEY68512.1 - 0.02 14.6 0.2 0.053 13.2 0.1 1.7 2 0 0 2 2 2 0 MlaA lipoprotein Oxidored_molyb PF00174.19 KEY68513.1 - 1.9e-47 161.1 0.0 3.3e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KEY68513.1 - 4.4e-21 75.3 4.7 8.4e-21 74.4 4.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 KEY68513.1 - 0.0048 17.6 0.1 0.0092 16.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig domain Evr1_Alr PF04777.13 KEY68516.1 - 1.7e-26 92.6 0.0 2.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KEY68516.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 1 1 2 2 2 0 APOBEC1 DUF2061 PF09834.9 KEY68516.1 - 1.7 9.2 4.5 2.2 8.9 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) Proteasome PF00227.26 KEY68517.1 - 3.7e-45 153.8 0.1 4.3e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 KEY68518.1 - 2.1e-20 73.7 3.6 2.4e-15 57.3 0.6 3.4 3 1 0 3 3 3 2 Cyclin CNDH2_M PF16869.5 KEY68518.1 - 0.0031 18.2 7.0 0.0031 18.2 7.0 3.9 3 1 0 3 3 3 1 PF16858 ADC PF06314.11 KEY68519.1 - 4.6e-07 29.6 0.2 8.8e-07 28.7 0.2 1.4 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Abhydrolase_3 PF07859.13 KEY68521.1 - 4.1e-30 105.2 0.0 6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY68521.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KEY68521.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KEY68521.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 KEY68521.1 - 0.21 10.4 0.0 0.63 8.8 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.7 KEY68521.1 - 0.25 11.9 9.0 0.23 12.0 7.4 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1993 PF09351.10 KEY68525.1 - 1.8e-46 158.2 0.0 2.1e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) adh_short PF00106.25 KEY68526.1 - 2.8e-23 82.4 1.0 4.3e-23 81.8 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68526.1 - 3.7e-16 59.4 1.5 5e-16 59.0 1.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68526.1 - 5.9e-07 29.6 0.1 1.6e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY68526.1 - 2e-05 24.2 0.6 0.00025 20.6 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY68526.1 - 0.016 15.1 0.6 0.043 13.7 0.6 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Fungal_trans_2 PF11951.8 KEY68527.1 - 1.9e-23 82.9 1.1 2.7e-23 82.4 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68527.1 - 2.7e-05 24.2 0.9 5.1e-05 23.3 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-REase-2 PF15646.6 KEY68527.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 HTH_IclR PF09339.10 KEY68527.1 - 0.12 12.2 0.9 5.4 6.9 0.1 3.5 4 0 0 4 4 4 0 IclR helix-turn-helix domain HET PF06985.11 KEY68528.1 - 1.7e-14 54.4 6.9 1e-11 45.4 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) THB PF18362.1 KEY68528.1 - 0.033 13.8 0.1 9.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Tri-helix bundle domain Ank_2 PF12796.7 KEY68529.1 - 2e-37 127.6 0.2 2.5e-12 47.2 0.0 4.5 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68529.1 - 5.6e-25 87.4 0.8 8.6e-10 39.0 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68529.1 - 7.6e-21 72.0 0.6 0.017 15.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KEY68529.1 - 4.2e-17 62.0 6.5 2.7e-06 27.6 0.0 5.8 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY68529.1 - 7.8e-15 54.6 6.2 0.045 14.2 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Helo_like_N PF17111.5 KEY68529.1 - 7.2e-05 22.2 0.9 8.2e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins DUF2520 PF10728.9 KEY68529.1 - 0.022 14.5 0.2 4.6 7.0 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2520) Sigma70_r1_1 PF03979.14 KEY68529.1 - 0.051 13.6 3.8 0.13 12.3 3.8 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 RXT2_N PF08595.11 KEY68529.1 - 0.14 12.2 0.8 0.22 11.6 0.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RVP PF00077.20 KEY68529.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease WSC PF01822.19 KEY68530.1 - 5.8e-52 173.8 61.3 1.6e-16 60.3 9.5 5.1 5 0 0 5 5 5 4 WSC domain ASH PF15780.5 KEY68530.1 - 0.047 13.9 8.5 0.094 12.9 0.2 3.5 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ_3 PF13570.6 KEY68530.1 - 0.17 12.4 0.0 0.17 12.4 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 KEY68530.1 - 0.75 9.8 3.8 69 3.6 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Toxin_35 PF10530.9 KEY68530.1 - 1.6 8.8 6.1 2.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Prok-RING_1 PF14446.6 KEY68530.1 - 1.7 8.7 5.8 0.29 11.1 1.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CFEM PF05730.11 KEY68531.1 - 7.1e-09 35.6 8.5 1.1e-08 35.1 8.5 1.3 1 0 0 1 1 1 1 CFEM domain Guanylate_cyc_2 PF09778.9 KEY68531.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Guanylylate cyclase Wzy_C PF04932.15 KEY68531.1 - 1.7 8.3 11.1 1 8.9 0.0 3.5 3 1 0 3 3 3 0 O-Antigen ligase Baculo_PEP_C PF04513.12 KEY68532.1 - 0.019 15.0 20.9 0.12 12.4 9.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL28A PF15177.6 KEY68532.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Interleukin-28A NPV_P10 PF05531.12 KEY68532.1 - 4.8 7.7 11.3 46 4.6 0.8 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BORCS6 PF10157.9 KEY68532.1 - 7.6 6.7 5.8 11 6.2 0.6 3.0 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 6 Pec_lyase_C PF00544.19 KEY68533.1 - 6.4e-23 81.4 8.2 7.6e-22 77.9 8.2 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY68533.1 - 1.1e-11 44.9 12.8 2.8e-09 37.0 6.4 2.2 1 1 1 2 2 2 2 Right handed beta helix region YrhK PF14145.6 KEY68534.1 - 0.95 9.4 26.1 0.23 11.4 0.6 4.7 2 2 1 4 4 4 0 YrhK-like protein adh_short PF00106.25 KEY68535.1 - 2.6e-34 118.4 0.0 1.6e-33 115.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68535.1 - 4.4e-21 75.5 0.0 7.7e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68535.1 - 1.2e-09 38.3 0.1 2.6e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY68535.1 - 0.0023 17.5 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY68535.1 - 0.092 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 KEY68536.1 - 5.2e-07 29.7 12.8 9.6e-07 28.8 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY68537.1 - 4.8e-08 32.7 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68537.1 - 8.2e-08 32.1 0.2 1.1e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 KEY68537.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KEY68537.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KEY68537.1 - 0.096 13.3 0.2 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.24 KEY68538.1 - 2.5e-40 139.1 0.0 3.8e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY68538.1 - 0.00016 21.9 0.0 0.00049 20.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Big_3_5 PF16640.5 KEY68538.1 - 0.17 12.1 1.5 4.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Helo_like_N PF17111.5 KEY68539.1 - 0.12 11.7 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zn_clus PF00172.18 KEY68540.1 - 2.1e-05 24.5 8.3 3.6e-05 23.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY68540.1 - 0.033 13.2 1.3 0.046 12.8 0.3 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Glyco_trans_4_3 PF12000.8 KEY68540.1 - 0.14 11.9 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 4 group CsbD PF05532.12 KEY68541.1 - 2.3e-22 78.7 18.5 8.5e-13 48.0 1.0 3.8 3 1 0 3 3 3 3 CsbD-like MFS_1 PF07690.16 KEY68542.1 - 1.5e-14 53.7 36.2 5e-12 45.4 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Gln-synt_C PF00120.24 KEY68544.1 - 9.3e-71 238.6 0.0 1.3e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KEY68544.1 - 4.8e-15 56.1 0.1 1.5e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Gln-synt_N_2 PF16952.5 KEY68544.1 - 0.047 13.5 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Response_reg PF00072.24 KEY68545.1 - 2.6e-27 95.2 0.3 5.3e-27 94.2 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KEY68545.1 - 1.4e-26 93.2 0.5 2.3e-24 86.1 0.5 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEY68545.1 - 1.7e-14 53.6 0.0 3.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEY68545.1 - 0.0009 19.6 0.0 0.099 13.0 0.0 2.7 2 0 0 2 2 2 1 HAMP domain KGK PF08872.10 KEY68545.1 - 0.0055 17.2 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 KGK domain Maf1 PF09174.10 KEY68546.1 - 2e-56 190.9 0.0 2.9e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KEY68546.1 - 2.3e-50 170.3 0.9 3.4e-50 169.7 0.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KEY68546.1 - 0.098 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Aldo_ket_red PF00248.21 KEY68547.1 - 2.1e-08 33.7 0.0 3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GlgS PF08971.11 KEY68547.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein Pkinase PF00069.25 KEY68548.1 - 3.4e-07 29.9 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEY68548.1 - 3.8e-07 29.7 0.0 2.4e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY68548.1 - 1.9e-05 24.7 1.2 0.014 15.3 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KEY68548.1 - 0.0016 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KEY68548.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase CMD PF02627.20 KEY68551.1 - 3.1e-07 30.4 0.1 2.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 KEY68551.1 - 0.2 11.5 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain FACT-Spt16_Nlob PF14826.6 KEY68552.1 - 1.6e-55 187.3 0.2 5.3e-55 185.6 0.2 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KEY68552.1 - 2.6e-55 186.7 0.1 2.6e-55 186.7 0.1 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KEY68552.1 - 1.7e-25 89.9 0.0 3.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KEY68552.1 - 4e-16 59.2 0.6 1.2e-15 57.7 0.2 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC50 PF03381.15 KEY68553.1 - 6.9e-97 324.3 0.0 8.6e-97 324.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Asp4 PF16996.5 KEY68553.1 - 0.11 12.3 0.7 0.25 11.1 0.7 1.6 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 T5orf172 PF10544.9 KEY68554.1 - 2.9e-10 40.6 0.2 1.2e-09 38.6 0.1 2.2 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KEY68554.1 - 3.7e-06 27.5 1.2 1.1e-05 26.0 0.1 2.5 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 DHquinase_II PF01220.19 KEY68554.1 - 0.16 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Dehydroquinase class II Transthyretin PF00576.21 KEY68556.1 - 5.8e-36 123.5 0.0 8.3e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family NPCBM_assoc PF10633.9 KEY68556.1 - 0.15 12.4 0.2 0.8 10.0 0.1 2.0 1 1 1 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Adenylsucc_synt PF00709.21 KEY68557.1 - 1.4e-148 495.3 0.0 5e-84 282.7 0.0 2.0 2 0 0 2 2 2 2 Adenylosuccinate synthetase ArsA_ATPase PF02374.15 KEY68558.1 - 7.6e-110 366.9 0.1 8.7e-110 366.7 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 KEY68558.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEY68558.1 - 1.9e-12 47.4 0.1 7.7e-12 45.5 0.0 2.0 2 2 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 KEY68558.1 - 4.7e-06 26.3 0.0 1.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KEY68558.1 - 4.4e-05 23.0 1.7 0.00033 20.2 0.2 2.5 2 1 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KEY68558.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KEY68558.1 - 0.00022 20.9 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEY68558.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEY68558.1 - 0.06 12.5 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KEY68558.1 - 0.096 13.1 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KEY68558.1 - 0.11 13.1 0.0 0.38 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CtIP_N PF10482.9 KEY68558.1 - 0.21 11.6 1.6 0.38 10.8 1.6 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF3496 PF12001.8 KEY68558.1 - 7.9 6.9 6.3 3.3 8.1 0.8 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF3496) DWNN PF08783.11 KEY68559.1 - 4.6e-28 97.3 0.0 8.2e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KEY68559.1 - 1.1e-09 37.9 5.5 1.9e-09 37.1 3.9 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KEY68559.1 - 0.00071 19.5 0.8 0.0013 18.7 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KEY68559.1 - 0.0027 17.5 8.9 0.0027 17.5 8.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KEY68559.1 - 0.0027 17.5 1.8 0.0054 16.6 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KEY68559.1 - 0.0055 16.5 5.0 0.012 15.4 5.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KEY68559.1 - 0.014 15.7 6.3 0.014 15.7 6.3 1.6 2 0 0 2 2 1 0 Ring finger domain zf-CCHC_3 PF13917.6 KEY68559.1 - 0.056 13.4 0.2 0.18 11.8 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF3332 PF11810.8 KEY68559.1 - 0.057 13.1 0.4 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) FYVE_2 PF02318.16 KEY68559.1 - 0.26 11.5 4.3 0.15 12.2 2.0 1.7 2 0 0 2 2 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 KEY68559.1 - 0.37 11.0 8.2 1.2 9.3 8.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KEY68559.1 - 0.79 9.6 8.7 1.6 8.7 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY68559.1 - 0.82 9.7 12.6 0.043 13.8 6.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain CDC45 PF02724.14 KEY68559.1 - 2.4 6.4 7.7 4.1 5.6 7.7 1.3 1 0 0 1 1 1 0 CDC45-like protein FTHFS PF01268.19 KEY68560.1 - 1.2e-254 845.7 1.9 2.3e-254 844.8 0.2 1.9 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KEY68560.1 - 6.3e-68 227.1 0.8 6.3e-68 227.1 0.8 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEY68560.1 - 2.8e-30 105.0 0.0 5.4e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 KEY68560.1 - 0.055 13.5 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_M20 PF01546.28 KEY68561.1 - 1.6e-33 116.2 0.0 2.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY68561.1 - 5.8e-12 45.5 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEY68561.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Yippee-Mis18 PF03226.14 KEY68562.1 - 6e-22 77.8 0.0 8.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KEY68562.1 - 0.00025 21.3 0.4 0.00046 20.4 0.4 1.4 1 1 0 1 1 1 1 C-terminal domain of RIG-I Trehalase PF01204.18 KEY68563.1 - 1.7e-191 637.5 0.0 2e-191 637.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KEY68563.1 - 3.3e-17 61.9 0.4 5.6e-17 61.2 0.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KEY68564.1 - 4.2e-294 975.9 0.0 4.7e-294 975.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KEY68564.1 - 1e-11 44.8 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.25 KEY68565.1 - 2.6e-72 243.4 0.0 3.7e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68565.1 - 9.1e-37 126.7 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KEY68565.1 - 9.2e-17 61.6 0.3 3.9e-09 37.0 0.0 3.1 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KEY68565.1 - 4.8e-15 55.4 0.1 8.8e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KEY68565.1 - 2.6e-07 30.3 0.0 5.1e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY68565.1 - 0.00015 20.9 0.3 0.00043 19.3 0.3 1.8 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KEY68565.1 - 0.00083 19.0 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 KEY68565.1 - 0.0034 16.3 0.1 0.0052 15.7 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KEY68565.1 - 0.072 13.0 0.3 0.47 10.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C14 PF00656.22 KEY68566.1 - 1.8e-60 204.9 0.2 3.9e-60 203.9 0.0 1.6 2 0 0 2 2 2 1 Caspase domain WW PF00397.26 KEY68567.1 - 1.4e-09 37.8 3.7 4e-09 36.4 3.7 1.8 1 0 0 1 1 1 1 WW domain TPR_2 PF07719.17 KEY68567.1 - 0.033 14.3 7.2 0.37 11.0 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat KinB_sensor PF16767.5 KEY68567.1 - 0.095 13.2 2.5 0.14 12.6 2.5 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TPR_10 PF13374.6 KEY68567.1 - 1.1 9.3 9.2 0.42 10.6 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68567.1 - 3.7 8.0 7.3 1.2 9.6 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3391 PF11871.8 KEY68567.1 - 4.4 7.8 5.4 10 6.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Epimerase PF01370.21 KEY68568.1 - 6.8e-10 38.8 0.5 0.0009 18.8 0.0 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY68568.1 - 1.5e-06 27.6 0.2 4.1e-06 26.2 0.2 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KEY68568.1 - 5.3e-06 26.5 0.2 1.4e-05 25.1 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY68568.1 - 7.4e-05 22.4 0.4 0.00017 21.2 0.4 1.6 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY68568.1 - 0.00036 20.1 0.5 0.013 14.9 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY68568.1 - 0.00053 19.1 0.1 0.0068 15.5 0.1 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEY68568.1 - 0.0017 17.8 0.0 0.046 13.2 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY68568.1 - 0.0029 17.5 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KEY68568.1 - 0.027 13.6 0.1 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Cutinase PF01083.22 KEY68569.1 - 1.7e-48 164.9 8.1 2.2e-48 164.6 8.1 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 KEY68569.1 - 2.5e-09 36.9 17.7 2.5e-09 36.9 17.7 4.5 4 2 1 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.11 KEY68569.1 - 3.9e-06 26.6 0.2 6.1e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KEY68569.1 - 0.00016 21.4 0.2 0.0002 21.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY68569.1 - 0.0032 18.1 0.2 0.0041 17.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY68569.1 - 0.04 13.2 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_7 PF13508.7 KEY68570.1 - 8.2e-06 26.2 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY68570.1 - 2.6e-05 24.4 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY68570.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FmiP_Thoc5 PF09766.9 KEY68572.1 - 0.096 12.0 3.9 0.047 13.0 1.8 1.5 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 TEX13 PF15186.6 KEY68573.1 - 0.015 15.0 2.6 0.018 14.7 2.6 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family EMC1_C PF07774.13 KEY68575.1 - 2.2e-74 249.8 0.0 3.5e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KEY68575.1 - 4e-17 62.6 8.5 5.6e-16 58.8 1.6 2.6 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KEY68575.1 - 0.00047 19.9 0.6 0.24 11.4 0.0 4.6 6 0 0 6 6 6 1 PQQ enzyme repeat Metallophos PF00149.28 KEY68577.1 - 3.2e-10 40.9 2.2 6.2e-10 39.9 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KEY68577.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain SLC35F PF06027.12 KEY68578.1 - 9.8e-103 343.8 19.2 1.3e-102 343.4 19.2 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KEY68578.1 - 1.5e-12 47.1 4.1 2.7e-12 46.3 4.1 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KEY68578.1 - 3.1e-10 40.3 35.4 1.4e-06 28.5 12.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family FTA2 PF13095.6 KEY68579.1 - 5e-57 193.0 0.0 1.1e-56 191.9 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 CALM_bind PF16025.5 KEY68582.1 - 1.5 9.3 6.9 2.9 8.4 6.7 1.6 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding DUF4685 PF15737.5 KEY68582.1 - 5.9 7.3 13.7 0.12 12.8 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) DHQ_synthase PF01761.20 KEY68583.1 - 5.4e-52 176.5 0.0 8.4e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KEY68583.1 - 5.2e-12 46.0 0.0 7.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 KEY68584.1 - 1.2e-12 47.4 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KEY68584.1 - 1.2e-11 45.5 0.0 2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 KEY68584.1 - 0.2 11.6 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase AhpC-TSA_2 PF13911.6 KEY68586.1 - 1.2e-06 28.6 0.1 1.9e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KEY68586.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Redoxin PAP_assoc PF03828.19 KEY68587.1 - 5.5e-16 58.5 0.2 1.4e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEY68587.1 - 7.4e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEY68587.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PYRIN PF02758.16 KEY68587.1 - 0.33 11.1 0.8 0.74 10.0 0.8 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DUF4148 PF13663.6 KEY68589.1 - 0.044 14.0 1.9 0.055 13.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PALP PF00291.25 KEY68590.1 - 2.4e-63 214.3 0.5 2.9e-63 214.0 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 KEY68590.1 - 0.034 13.6 0.4 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) ADH_N PF08240.12 KEY68591.1 - 2.4e-20 72.4 4.7 4.1e-20 71.7 4.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY68591.1 - 1.1e-11 44.8 0.0 3.7e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY68591.1 - 0.00012 21.5 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY68591.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEY68591.1 - 0.0096 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEY68591.1 - 0.091 12.1 0.8 0.15 11.4 0.8 1.2 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_C PF16653.5 KEY68592.1 - 2e-92 310.1 0.0 4.6e-92 308.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KEY68592.1 - 3.6e-26 92.0 0.1 5.5e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEY68592.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KEY68592.1 - 4.8e-05 23.4 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KEY68592.1 - 0.0059 16.2 0.2 0.044 13.4 0.0 2.3 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KEY68592.1 - 0.046 14.6 0.0 0.084 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SieB PF14163.6 KEY68592.1 - 0.12 11.8 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B NAD_binding_3 PF03447.16 KEY68592.1 - 0.17 12.5 0.1 0.3 11.8 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain KCNQC3-Ank-G_bd PF11956.8 KEY68593.1 - 1.7 9.0 9.5 3.2 8.1 0.4 3.3 3 0 0 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 Rhodanese PF00581.20 KEY68594.1 - 0.00044 20.7 0.0 0.00069 20.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain bZIP_1 PF00170.21 KEY68595.1 - 0.0025 17.9 5.6 0.0052 16.9 5.6 1.6 1 1 0 1 1 1 1 bZIP transcription factor Nuc_N PF14448.6 KEY68595.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Nuclease N terminal FMN_red PF03358.15 KEY68596.1 - 1e-23 83.8 0.0 2.6e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase MFS_1 PF07690.16 KEY68597.1 - 3.4e-22 78.9 47.5 9.1e-12 44.6 19.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68597.1 - 2.2e-05 23.5 7.4 2.2e-05 23.5 7.4 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter Pkinase PF00069.25 KEY68598.1 - 2.6e-19 69.6 0.0 2.2e-08 33.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68598.1 - 9.7e-09 34.9 1.7 0.0011 18.3 0.0 3.4 4 1 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY68598.1 - 5.1e-05 22.7 0.4 0.025 13.9 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KEY68598.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_11 PF08241.12 KEY68599.1 - 5.7e-11 42.9 0.0 9.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68599.1 - 1.5e-10 41.7 0.0 3.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY68599.1 - 7.6e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEY68599.1 - 7.3e-09 35.7 0.0 9.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY68599.1 - 1.1e-06 29.2 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68599.1 - 3.5e-06 26.9 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 KEY68600.1 - 1.4e-62 212.1 0.0 2.3e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KEY68600.1 - 5.1e-62 209.7 0.3 1.2e-61 208.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY68600.1 - 2.3e-59 200.3 0.1 1.1e-58 198.1 0.1 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KEY68600.1 - 1.1e-58 198.9 0.0 1.5e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY68600.1 - 5.6e-32 110.2 0.0 1.6e-31 108.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY68600.1 - 1.5e-22 80.2 0.0 5.2e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KEY68600.1 - 1.5e-21 77.0 0.0 3.6e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEY68600.1 - 1.8e-13 50.6 3.5 3.5e-13 49.7 0.1 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KEY68600.1 - 2.3e-12 46.9 0.0 6.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEY68600.1 - 2.5e-12 48.0 0.0 3.1e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KEY68600.1 - 2.2e-11 44.3 0.0 1.6e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY68600.1 - 8.6e-09 35.9 0.0 2.6e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY68600.1 - 6.5e-08 32.6 0.1 2.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KEY68600.1 - 7e-06 25.6 0.0 1.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KEY68600.1 - 1.7e-05 24.3 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KEY68600.1 - 8.4e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY68600.1 - 0.00018 21.8 0.0 0.00057 20.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KEY68600.1 - 0.0018 18.0 0.0 0.041 13.6 0.0 2.6 2 1 0 2 2 2 1 Lysine methyltransferase DUF938 PF06080.12 KEY68600.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Thiolase_N PF00108.23 KEY68600.1 - 0.026 13.9 0.7 0.062 12.6 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain TMEM126 PF07114.11 KEY68600.1 - 0.2 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 126 Thioesterase PF00975.20 KEY68601.1 - 3.3e-14 53.6 0.0 3.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEY68601.1 - 0.003 18.2 0.0 0.0051 17.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KEY68601.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEY68601.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KEY68602.1 - 8.4e-48 163.2 0.1 1.1e-47 162.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps26 PF03643.15 KEY68602.1 - 0.071 12.1 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Pyr_redox_2 PF07992.14 KEY68603.1 - 5.7e-13 48.8 0.0 3.7e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY68603.1 - 3.9e-09 36.6 0.0 2.1e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KEY68603.1 - 5e-09 35.1 0.1 1.6e-08 33.4 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY68603.1 - 8e-07 28.6 0.0 4.6e-06 26.1 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY68603.1 - 0.00036 19.8 0.0 0.0018 17.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KEY68603.1 - 0.00096 19.2 0.0 0.72 9.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KEY68603.1 - 0.001 19.1 0.0 0.38 10.7 0.0 2.9 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEY68603.1 - 0.0094 16.5 0.0 0.1 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY68603.1 - 0.016 14.3 0.0 2.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KEY68603.1 - 0.061 12.6 0.0 0.47 9.7 0.0 2.2 2 1 0 2 2 2 0 Thi4 family DAO PF01266.24 KEY68603.1 - 0.065 12.8 0.0 0.2 11.2 0.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KEY68604.1 - 1.2e-32 113.2 38.2 1.2e-32 113.2 38.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4191 PF13829.6 KEY68604.1 - 5.5 6.3 5.1 1.9 7.8 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) SnoaL_2 PF12680.7 KEY68605.1 - 8e-06 26.4 0.1 1.1e-05 26.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain PAF-AH_p_II PF03403.13 KEY68607.1 - 6.5e-31 107.2 0.0 9.3e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KEY68607.1 - 0.00034 19.6 0.1 0.0029 16.6 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KEY68607.1 - 0.004 16.4 0.4 0.26 10.5 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KEY68607.1 - 0.08 11.9 0.0 0.58 9.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Fanconi_A PF03511.14 KEY68607.1 - 4.3 7.3 5.6 6.2 6.8 4.4 1.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein Peptidase_S8 PF00082.22 KEY68609.1 - 2.3e-35 122.3 8.3 3.8e-35 121.6 8.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY68609.1 - 2.7e-20 72.8 0.6 5.4e-20 71.8 0.6 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 KEY68610.1 - 1.7e-120 401.5 0.0 3e-120 400.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KEY68610.1 - 6.9e-12 45.3 1.8 1e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KEY68610.1 - 6.8e-10 39.3 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 KEY68610.1 - 0.00067 19.0 0.5 0.0016 17.7 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF4704 PF15787.5 KEY68610.1 - 0.013 14.8 0.8 0.083 12.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4704) DDOST_48kD PF03345.14 KEY68612.1 - 9.3e-157 522.1 0.0 1.1e-156 521.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.12 KEY68613.1 - 2.2e-90 302.7 0.2 2.6e-90 302.4 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KEY68613.1 - 0.033 14.2 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 YolD-like protein CorA PF01544.18 KEY68615.1 - 1.3e-10 41.1 1.1 3.6e-10 39.6 1.1 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Aa_trans PF01490.18 KEY68616.1 - 1e-23 83.8 27.7 1.3e-23 83.4 27.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short_C2 PF13561.6 KEY68617.1 - 1.3e-59 201.6 0.1 1.5e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY68617.1 - 7.9e-41 139.7 0.1 9.6e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY68617.1 - 4.8e-09 36.4 0.7 7.3e-09 35.8 0.7 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY68617.1 - 0.0002 21.3 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KEY68617.1 - 0.009 16.7 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KEY68617.1 - 0.019 14.3 0.1 0.044 13.1 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_12 PF08242.12 KEY68617.1 - 0.086 13.6 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KEY68617.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RecC_C PF17946.1 KEY68617.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain Ribosomal_S28e PF01200.18 KEY68618.1 - 6.9e-32 109.2 1.5 7.6e-32 109.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e IBR PF01485.21 KEY68619.1 - 9.4e-07 29.0 21.8 0.0037 17.5 2.6 3.7 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KEY68619.1 - 4.9 7.1 29.4 2.7 7.9 3.5 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PNISR PF15996.5 KEY68620.1 - 0.67 10.2 10.3 0.97 9.7 10.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SRP-alpha_N PF04086.13 KEY68620.1 - 1.9 8.3 12.5 2.9 7.8 12.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RCR PF12273.8 KEY68622.1 - 0.0045 17.6 0.1 0.0063 17.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2484 PF10658.9 KEY68622.1 - 0.077 13.3 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) Adeno_E3_CR2 PF02439.15 KEY68622.1 - 0.22 11.3 0.2 0.36 10.6 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sugar_tr PF00083.24 KEY68623.1 - 2.8e-123 412.1 23.7 3.3e-123 411.9 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68623.1 - 2.5e-19 69.4 30.2 2.5e-19 69.4 30.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 KEY68623.1 - 0.025 14.6 0.3 0.025 14.6 0.3 3.8 5 1 0 5 5 5 0 Protein of unknown function (DUF1304) G-alpha PF00503.20 KEY68626.1 - 2.7e-29 102.5 0.0 3.3e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Acetyltransf_3 PF13302.7 KEY68627.1 - 0.042 14.5 0.1 0.077 13.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ceramidse_alk_C PF17048.5 KEY68627.1 - 0.19 11.6 0.2 0.48 10.3 0.2 1.6 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal EAF PF09816.9 KEY68628.1 - 2.2e-21 76.1 0.0 5.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ribosomal_60s PF00428.19 KEY68628.1 - 0.012 16.1 5.6 0.012 16.1 5.6 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein GFA PF04828.14 KEY68629.1 - 9.2e-08 32.3 0.1 1.3e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme POP1 PF06978.11 KEY68630.1 - 5.3e-73 245.4 11.5 5.3e-73 245.4 11.5 1.6 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KEY68630.1 - 3.5e-29 101.0 0.2 1e-28 99.5 0.2 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.9 KEY68631.1 - 5.2e-28 97.6 0.0 3.9e-27 94.8 0.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.20 KEY68632.1 - 2.5e-77 260.5 5.6 3.9e-77 259.8 5.6 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY68632.1 - 7.2e-06 25.0 0.3 1.3e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KEY68632.1 - 0.00053 19.7 1.0 0.001 18.9 0.2 1.7 2 0 0 2 2 2 1 Periplasmic binding protein DUF3221 PF11518.8 KEY68632.1 - 0.054 13.8 0.6 0.14 12.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) BRAP2 PF07576.12 KEY68632.1 - 0.084 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 Rrp40_N PF18311.1 KEY68633.1 - 5.4e-17 61.5 0.2 1.7e-16 59.9 0.2 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KEY68633.1 - 1.9e-15 56.9 0.0 4.7e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-C2H2 PF00096.26 KEY68634.1 - 0.0021 18.4 9.0 0.014 15.8 3.2 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KEY68634.1 - 0.0058 17.2 2.4 0.0058 17.2 2.4 2.2 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KEY68634.1 - 0.054 13.6 1.1 0.11 12.6 1.1 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KEY68634.1 - 0.071 14.0 12.3 0.093 13.6 2.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_12 PF13087.6 KEY68635.1 - 1.2e-22 80.5 0.0 4.1e-21 75.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KEY68635.1 - 1.8e-14 54.2 0.0 3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEY68635.1 - 6.6e-08 32.3 0.1 2.6e-07 30.4 0.1 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KEY68635.1 - 0.00026 20.8 0.0 0.062 13.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DNA_methylase PF00145.17 KEY68636.1 - 1.6e-40 139.5 0.0 2e-28 99.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 KEY68636.1 - 0.037 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SEN1_N PF12726.7 KEY68637.1 - 3.8e-207 690.0 0.8 5e-207 689.7 0.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KEY68637.1 - 4.3e-73 246.3 3.7 4.3e-73 246.3 3.7 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KEY68637.1 - 4.3e-62 209.3 0.0 7.4e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY68637.1 - 1.8e-08 34.9 0.8 1e-07 32.4 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY68637.1 - 3.4e-08 33.5 3.3 0.00016 21.4 2.5 3.0 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEY68637.1 - 0.00011 22.1 0.0 0.21 11.3 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KEY68637.1 - 0.00066 19.3 11.5 0.002 17.7 3.3 3.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KEY68637.1 - 0.028 14.7 0.0 0.14 12.4 0.0 2.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KEY68640.1 - 3.2e-10 39.8 0.0 5.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68640.1 - 6e-07 29.2 0.0 5.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68640.1 - 0.00082 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY68640.1 - 0.1 12.5 0.4 0.35 10.7 0.4 1.8 1 1 0 1 1 1 0 NAD(P)H-binding fn3_2 PF16893.5 KEY68641.1 - 3.5e-39 132.8 0.1 5.7e-39 132.1 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KEY68641.1 - 3.4e-23 81.3 0.9 5.8e-23 80.6 0.9 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KEY68641.1 - 4.7e-13 48.9 0.0 8.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KEY68641.1 - 1.7e-11 44.3 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEY68641.1 - 8.5e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KEY68641.1 - 0.00019 21.7 0.0 0.0008 19.7 0.0 2.0 2 1 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.8 KEY68641.1 - 0.00081 19.6 0.0 0.0032 17.7 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) TFIIF_alpha PF05793.12 KEY68641.1 - 8 4.9 21.7 11 4.5 21.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1485 PF07364.12 KEY68642.1 - 0.067 12.5 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 eIF-1a PF01176.19 KEY68643.1 - 2e-21 75.5 0.0 2.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 KEY68644.1 - 4e-25 87.9 0.1 5.7e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KEY68644.1 - 2.4e-06 27.2 0.4 6e-06 25.9 0.4 1.7 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 KEY68646.1 - 7.9e-20 71.6 0.0 2.1e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain CorA PF01544.18 KEY68648.1 - 1.5e-16 60.6 0.5 2.3e-16 60.0 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cyclin PF08613.11 KEY68650.1 - 3e-06 27.7 0.0 3e-06 27.7 0.0 3.0 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KEY68650.1 - 0.021 14.6 0.0 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain DEAD PF00270.29 KEY68651.1 - 5.5e-38 130.5 0.0 9.4e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68651.1 - 1.1e-24 86.9 0.4 1.7e-23 83.1 0.3 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY68651.1 - 4.6e-08 33.2 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KEY68651.1 - 0.0021 18.6 0.3 0.0055 17.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) Rpr2 PF04032.16 KEY68652.1 - 1.2e-25 89.6 0.3 1.5e-25 89.2 0.3 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 KEY68652.1 - 0.00039 20.2 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF4674 PF15719.5 KEY68652.1 - 0.019 15.0 2.6 0.093 12.8 1.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) zf-BED PF02892.15 KEY68652.1 - 0.066 13.2 1.1 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger DASH_Hsk3 PF08227.11 KEY68653.1 - 1.6e-21 76.4 4.6 2.7e-21 75.6 4.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ApbA PF02558.16 KEY68654.1 - 1.4e-25 89.7 0.0 2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEY68654.1 - 6.4e-21 74.8 0.0 9.6e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Troponin-I_N PF11636.8 KEY68655.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 OPT PF03169.15 KEY68656.1 - 4.6e-185 616.8 53.2 5.2e-185 616.6 53.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.18 KEY68656.1 - 0.22 10.2 1.1 0.29 9.8 0.1 1.6 2 0 0 2 2 2 0 EIAV coat protein, gp90 Ribosomal_L37e PF01907.19 KEY68657.1 - 3.8e-27 94.2 10.3 5.9e-27 93.6 10.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e zf-C4pol PF14260.6 KEY68657.1 - 0.014 15.8 0.9 0.023 15.1 0.9 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 KEY68657.1 - 0.016 15.2 1.2 0.024 14.7 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KEY68657.1 - 0.024 14.6 0.5 0.031 14.3 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KEY68657.1 - 0.048 13.8 2.2 0.064 13.4 2.2 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rubredoxin_2 PF18073.1 KEY68657.1 - 0.11 12.2 2.3 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 KEY68657.1 - 0.36 10.6 3.3 11 5.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KEY68657.1 - 0.88 9.5 5.5 1.4 8.8 5.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 KEY68657.1 - 1 8.8 4.1 0.75 9.2 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) ELP6 PF09807.9 KEY68658.1 - 3.8e-12 46.2 0.0 8.8e-12 45.0 0.0 1.5 2 0 0 2 2 2 1 Elongation complex protein 6 ATPase PF06745.13 KEY68658.1 - 3e-08 33.3 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 KaiC Thioredoxin PF00085.20 KEY68659.1 - 3.2e-07 30.3 0.0 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY68659.1 - 0.078 13.4 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Sel1 PF08238.12 KEY68660.1 - 1e-48 162.7 17.4 3.5e-09 37.1 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_19 PF14559.6 KEY68660.1 - 0.3 11.6 8.2 10 6.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CBP4 PF07960.11 KEY68662.1 - 4.9e-27 94.3 1.4 8e-27 93.6 1.4 1.3 1 0 0 1 1 1 1 CBP4 DUF3103 PF11301.8 KEY68662.1 - 0.04 12.7 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) NAC PF01849.18 KEY68663.1 - 1.3e-23 82.7 0.3 1.3e-23 82.7 0.3 1.6 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.18 KEY68664.1 - 4.8e-32 111.7 0.0 5.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L24e PF01246.20 KEY68665.1 - 3.3e-29 100.9 0.1 8.1e-29 99.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Redoxin PF08534.10 KEY68666.1 - 3e-33 114.6 0.3 3.4e-33 114.4 0.3 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEY68666.1 - 4.3e-13 49.3 0.1 5.4e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family MqsA_antitoxin PF15731.5 KEY68666.1 - 0.17 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF1348 PF07080.11 KEY68667.1 - 2.6e-65 218.2 9.8 3.2e-65 217.9 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KEY68667.1 - 2.1e-07 31.5 1.6 2.9e-07 31.0 1.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KEY68667.1 - 4.5e-06 27.0 0.2 6.5e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) RGS PF00615.19 KEY68669.1 - 4e-05 23.9 0.2 0.0067 16.7 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF3291 PF11695.8 KEY68669.1 - 0.0026 17.4 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3291) COX4_pro PF03626.14 KEY68669.1 - 9.8 6.7 11.3 0.087 13.3 3.2 1.7 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Fumble PF03630.14 KEY68670.1 - 7.4e-144 479.0 0.1 9.1e-144 478.7 0.1 1.1 1 0 0 1 1 1 1 Fumble 2OG-FeII_Oxy_3 PF13640.6 KEY68674.1 - 2.6e-06 28.3 0.0 4.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.12 KEY68675.1 - 2.7e-182 607.5 0.0 3.4e-182 607.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KEY68675.1 - 0.0061 16.3 0.0 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 KEY68676.1 - 1.3e-60 205.1 0.1 2.6e-60 204.2 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEY68676.1 - 1e-32 112.8 0.0 2.4e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain bMG3 PF11974.8 KEY68676.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain SepSecS PF05889.13 KEY68676.1 - 0.094 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Ribosomal_S4e PF00900.20 KEY68677.1 - 5.9e-37 125.4 0.2 1.2e-36 124.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KEY68677.1 - 4.6e-24 83.8 0.1 8e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KEY68677.1 - 8.3e-18 64.2 3.3 1.6e-17 63.3 3.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KEY68677.1 - 2.1e-05 24.2 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KEY68677.1 - 6.8e-05 22.7 2.1 6.8e-05 22.7 2.1 3.1 4 0 0 4 4 4 1 KOW motif SH3_18 PF18354.1 KEY68677.1 - 0.11 12.5 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 CarS bacterial SH3 domain Myb_DNA-binding PF00249.31 KEY68678.1 - 4.2e-13 49.3 0.0 7.2e-08 32.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY68678.1 - 1.9e-09 37.6 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KEY68678.1 - 5.4e-06 26.4 0.2 0.038 14.0 0.0 2.5 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KEY68678.1 - 0.0099 16.1 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 GREB1 PF15782.5 KEY68680.1 - 0.24 8.5 4.7 0.34 8.0 4.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Septin PF00735.18 KEY68681.1 - 5.6e-34 117.7 0.1 1.3e-11 44.4 0.0 3.3 3 0 0 3 3 3 3 Septin AAA_23 PF13476.6 KEY68681.1 - 0.00053 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY68681.1 - 0.0063 16.9 0.2 0.037 14.4 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEY68681.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 KEY68681.1 - 0.024 13.8 0.0 0.06 12.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 KEY68681.1 - 0.025 13.9 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pox_A32 PF04665.12 KEY68681.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 KEY68681.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEY68681.1 - 0.067 12.4 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KEY68681.1 - 0.07 13.7 0.0 0.37 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY68681.1 - 0.083 12.6 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KEY68681.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain WSK PF03832.13 KEY68681.1 - 2.9 7.7 7.2 3.7 7.3 1.4 3.0 2 0 0 2 2 2 0 WSK motif ABC1 PF03109.16 KEY68682.1 - 3.8e-21 75.5 0.0 8.5e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KEY68682.1 - 0.00084 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family SUR7 PF06687.12 KEY68683.1 - 5.8e-23 81.6 10.9 5.8e-23 81.6 10.9 1.4 2 0 0 2 2 2 1 SUR7/PalI family Pex24p PF06398.11 KEY68683.1 - 0.28 10.1 0.0 0.44 9.5 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1179 PF06678.11 KEY68683.1 - 0.29 11.1 5.2 1.4 9.0 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) CDP-OH_P_transf PF01066.21 KEY68685.1 - 1.9e-16 60.6 0.2 1.9e-16 60.6 0.2 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.21 KEY68686.1 - 3.7e-07 30.1 13.3 5.5e-07 29.6 13.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KEY68686.1 - 5.4e-06 26.4 0.0 5.4e-06 26.4 0.0 2.8 1 1 1 3 3 3 1 Transcription factor PAP1 bZIP_Maf PF03131.17 KEY68686.1 - 0.00066 20.1 8.3 0.0011 19.5 8.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Rootletin PF15035.6 KEY68686.1 - 0.0099 15.9 3.0 0.014 15.4 3.0 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 KEY68686.1 - 0.03 12.3 2.0 0.037 12.0 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 KEY68686.1 - 0.078 13.1 13.7 0.14 12.3 12.9 1.7 1 1 0 1 1 1 0 Basic region leucine zipper SHE3 PF17078.5 KEY68686.1 - 0.21 11.3 6.6 0.48 10.1 6.6 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 GvpL_GvpF PF06386.11 KEY68686.1 - 7.3 6.4 8.0 11 5.9 7.5 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Raptor_N PF14538.6 KEY68687.1 - 9.5e-64 213.8 0.0 1.7e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain BBS2_Mid PF14783.6 KEY68687.1 - 1.7e-05 24.8 0.0 0.24 11.4 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KEY68687.1 - 3.4e-05 24.5 6.4 2.2 9.3 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Atx10homo_assoc PF09759.9 KEY68687.1 - 0.0014 18.6 0.2 0.0028 17.7 0.2 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KEY68687.1 - 0.035 14.4 0.2 27 5.4 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Nup160 PF11715.8 KEY68687.1 - 0.047 12.3 0.0 0.11 11.1 0.1 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HEAT_2 PF13646.6 KEY68687.1 - 0.074 13.4 0.2 5.7 7.4 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Kelch_4 PF13418.6 KEY68688.1 - 1.8e-31 107.9 7.2 2.4e-05 24.3 0.2 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KEY68688.1 - 1.1e-27 95.5 6.9 2.5e-07 30.5 0.0 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 KEY68688.1 - 3e-27 94.3 6.8 2.6e-06 27.6 0.2 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KEY68688.1 - 2e-26 91.3 0.3 2.1e-09 36.8 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KEY68688.1 - 2.2e-25 88.0 3.6 4.9e-09 36.2 0.2 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KEY68688.1 - 2.3e-17 62.2 10.9 1.1e-05 25.2 0.3 6.6 6 1 0 6 6 6 5 Kelch motif SMC_N PF02463.19 KEY68689.1 - 1.7e-26 93.0 0.0 2.9e-26 92.3 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEY68689.1 - 1.9e-18 67.7 0.0 1.9e-18 67.7 0.0 5.1 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.6 KEY68689.1 - 2.4e-13 50.5 0.0 1.5e-06 28.2 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KEY68689.1 - 5.7e-07 29.6 6.3 0.0019 18.1 0.0 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system BLOC1_2 PF10046.9 KEY68689.1 - 0.0049 17.1 0.9 0.0049 17.1 0.9 7.0 4 3 2 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.6 KEY68689.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KEY68689.1 - 0.047 14.1 0.1 0.32 11.4 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KEY68689.1 - 0.15 12.0 0.8 1.2 9.1 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase Baculo_PEP_C PF04513.12 KEY68689.1 - 0.62 10.1 0.0 0.62 10.1 0.0 6.0 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 KEY68689.1 - 0.92 10.0 92.6 0.21 12.1 12.3 6.1 2 2 3 5 5 4 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KEY68689.1 - 2.9 8.1 78.6 0.065 13.4 2.8 6.5 4 2 1 5 5 5 0 Tropomyosin like AAA_25 PF13481.6 KEY68689.1 - 4.4 6.8 6.0 1.9 8.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Synaptonemal_3 PF15191.6 KEY68689.1 - 4.5 7.1 8.9 5 7.0 0.1 4.3 5 0 0 5 5 5 0 Synaptonemal complex central element protein 3 DUF1664 PF07889.12 KEY68689.1 - 6.1 6.9 43.6 2.8 8.0 2.7 6.9 5 2 1 7 7 7 0 Protein of unknown function (DUF1664) Arteri_nucleo PF01481.16 KEY68689.1 - 6.7 7.1 8.4 1 9.6 0.7 3.4 3 0 0 3 3 3 0 Arterivirus nucleocapsid protein MAD PF05557.13 KEY68689.1 - 6.7 4.9 79.7 0.097 11.0 16.9 3.4 2 1 1 3 3 3 0 Mitotic checkpoint protein Octopine_DH PF02317.17 KEY68689.1 - 9.1 6.4 7.8 1 9.4 0.4 2.9 2 1 1 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Pkinase PF00069.25 KEY68690.1 - 1.2e-67 228.1 0.1 8.8e-67 225.2 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KEY68690.1 - 2.4e-41 140.1 1.3 5.2e-41 139.1 1.3 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KEY68690.1 - 1.4e-37 129.4 0.0 9.6e-37 126.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY68690.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY68690.1 - 0.00035 19.6 0.1 0.00076 18.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KEY68690.1 - 0.057 13.0 0.3 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 KEY68690.1 - 0.063 12.9 0.9 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KEY68690.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KEY68690.1 - 0.099 12.0 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ctr PF04145.15 KEY68691.1 - 5.8e-30 104.9 2.8 8e-30 104.4 2.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family HTH_32 PF13565.6 KEY68691.1 - 0.16 12.6 0.1 2.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain SRF-TF PF00319.18 KEY68692.1 - 4.6e-21 74.0 0.1 6.4e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MRI PF15325.6 KEY68692.1 - 2.5 9.2 4.6 0.85 10.7 0.5 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection Tetraspanin PF00335.20 KEY68693.1 - 0.0023 17.7 6.8 0.0083 15.9 6.8 2.1 1 1 0 1 1 1 1 Tetraspanin family Sensor PF13796.6 KEY68693.1 - 0.13 12.3 7.0 1.8 8.6 5.9 2.3 2 1 0 2 2 2 0 Putative sensor DoxX PF07681.12 KEY68693.1 - 0.2 12.3 7.3 0.08 13.5 4.0 2.0 3 0 0 3 3 3 0 DoxX Phage_holin_3_6 PF07332.11 KEY68693.1 - 8 6.5 10.1 2 8.5 4.8 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Mg_trans_NIPA PF05653.14 KEY68694.1 - 8.8e-15 54.6 11.9 1.4e-14 54.0 11.9 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 KEY68694.1 - 0.00015 21.1 1.1 0.00015 21.1 1.1 2.4 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport EamA PF00892.20 KEY68694.1 - 0.00061 20.0 19.6 0.0015 18.7 0.1 3.0 2 1 0 2 2 2 1 EamA-like transporter family vATP-synt_E PF01991.18 KEY68695.1 - 1.7e-66 223.4 9.2 1.9e-66 223.3 9.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 KEY68695.1 - 0.00069 19.7 0.2 0.0031 17.6 0.1 2.2 1 1 1 2 2 2 1 Flagellar assembly protein FliH Methyltransf_7 PF03492.15 KEY68695.1 - 0.09 12.0 1.1 0.93 8.6 1.4 1.9 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Malate_synthase PF01274.22 KEY68697.1 - 1.6e-223 742.7 0.0 1.9e-223 742.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PhoLip_ATPase_C PF16212.5 KEY68698.1 - 1e-76 258.0 28.0 1e-76 258.0 28.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEY68698.1 - 1.8e-20 72.4 1.3 4.8e-20 71.0 1.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KEY68698.1 - 1.5e-12 47.4 0.0 1.1e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEY68698.1 - 8.2e-10 39.3 5.3 2.5e-06 27.9 1.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEY68698.1 - 0.0007 19.2 0.0 0.0024 17.4 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEY68698.1 - 0.016 14.9 0.4 0.034 13.9 0.4 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 KEY68698.1 - 1.5 9.0 8.3 1.3 9.1 6.2 2.1 2 0 0 2 2 2 0 C-terminus of AA_permease Aldedh PF00171.22 KEY68699.1 - 1.3e-118 396.5 0.1 1.5e-118 396.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 KEY68700.1 - 1.3e-43 148.8 0.0 2.1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68700.1 - 2.3e-28 98.7 0.0 5.5e-26 91.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEY68700.1 - 0.0017 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEY68700.1 - 0.0075 16.3 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1860 PF08949.10 KEY68700.1 - 0.039 13.7 0.7 0.069 12.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) UTP25 PF06862.12 KEY68700.1 - 0.26 10.0 0.0 9.7 4.8 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ipi1_N PF12333.8 KEY68701.1 - 3.9e-27 94.8 0.6 3.9e-27 94.8 0.6 2.7 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation L_biotic_typeA PF04604.13 KEY68701.1 - 0.098 12.5 0.2 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Type-A lantibiotic Robl_LC7 PF03259.17 KEY68702.1 - 2.7e-08 33.4 0.0 3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain UPF0139 PF03669.13 KEY68704.1 - 2.5e-06 27.3 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) GRP PF07172.11 KEY68706.1 - 0.028 15.1 10.8 0.028 15.1 10.8 5.6 2 1 0 2 2 2 0 Glycine rich protein family S1-P1_nuclease PF02265.16 KEY68707.1 - 1.9e-69 234.3 0.1 2.1e-69 234.1 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.14 KEY68708.1 - 3e-26 91.0 16.3 7.2e-16 57.7 1.9 4.7 5 0 0 5 5 5 3 PQ loop repeat Semialdhyde_dhC PF02774.18 KEY68709.1 - 9.6e-39 133.4 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KEY68709.1 - 6.6e-29 100.8 0.0 1.6e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KEY68709.1 - 0.027 15.3 0.0 0.048 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KEY68709.1 - 0.033 14.4 0.1 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KEY68709.1 - 0.048 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.6 KEY68710.1 - 1.9e-12 47.3 5.1 3e-12 46.7 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEY68710.1 - 3.2e-09 36.9 2.1 6.5e-09 35.9 2.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 KEY68710.1 - 3.6e-09 36.5 0.0 8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KEY68710.1 - 5.3e-09 35.8 4.4 8.6e-09 35.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY68710.1 - 1.6e-08 34.3 3.1 2.5e-08 33.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEY68710.1 - 2.1e-08 33.8 2.6 2.1e-08 33.8 2.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KEY68710.1 - 9e-07 28.8 2.2 1.4e-06 28.2 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEY68710.1 - 1.6e-05 24.7 2.8 2.4e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY68710.1 - 2.6e-05 24.1 2.2 4.9e-05 23.3 0.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEY68710.1 - 0.0014 18.6 1.1 0.0026 17.8 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEY68710.1 - 0.0096 15.8 3.1 0.017 15.0 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEY68710.1 - 0.014 15.6 2.5 0.031 14.4 2.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KEY68710.1 - 0.065 12.9 3.2 0.13 11.9 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KEY68710.1 - 0.13 12.5 2.1 0.35 11.1 2.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KEY68710.1 - 0.2 12.0 3.2 0.37 11.1 3.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KEY68710.1 - 0.21 11.7 2.1 0.44 10.7 2.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KEY68710.1 - 0.22 11.3 2.7 0.54 10.1 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KEY68710.1 - 0.95 9.4 2.7 1.7 8.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger GvpK PF05121.12 KEY68712.1 - 0.0047 16.9 4.4 0.0047 16.9 4.4 2.6 1 1 1 2 2 2 1 Gas vesicle protein K OmpH PF03938.14 KEY68712.1 - 0.0089 16.4 17.3 0.015 15.7 2.3 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Spc24 PF08286.11 KEY68712.1 - 0.027 14.7 1.5 0.027 14.7 1.5 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 KEY68712.1 - 0.081 11.8 4.4 0.084 11.8 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 KEY68712.1 - 0.096 12.2 7.8 0.071 12.7 1.0 2.3 2 0 0 2 2 2 0 fzo-like conserved region CENP-F_leu_zip PF10473.9 KEY68712.1 - 0.15 12.1 21.8 0.07 13.2 8.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KEY68712.1 - 0.28 11.5 10.3 0.053 13.8 4.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KEY68712.1 - 0.32 9.8 26.0 0.12 11.2 9.0 2.9 2 1 0 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KEY68712.1 - 0.56 10.0 20.7 0.44 10.4 3.6 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Csm2_III-A PF03750.13 KEY68712.1 - 0.63 10.9 6.1 0.44 11.4 3.4 2.1 1 1 1 2 2 2 0 Csm2 Type III-A Filament PF00038.21 KEY68712.1 - 1.2 8.6 22.7 22 4.5 22.7 2.1 1 1 0 1 1 1 0 Intermediate filament protein Cluap1 PF10234.9 KEY68712.1 - 2.1 7.7 17.4 13 5.1 17.1 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 ERM PF00769.19 KEY68712.1 - 2.3 7.9 25.8 4.1 7.1 25.8 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 KEY68712.1 - 3.8 6.5 22.3 47 2.9 22.3 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KEY68712.1 - 5.3 7.1 5.5 14 5.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KEY68712.1 - 9.5 6.6 21.5 29 5.1 21.4 1.8 1 1 0 1 1 1 0 Fez1 Zn_clus PF00172.18 KEY68713.1 - 8.3e-08 32.2 12.0 1.3e-07 31.6 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LANC_like PF05147.13 KEY68714.1 - 1.3e-25 89.7 0.0 2.2e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein EI24 PF07264.11 KEY68715.1 - 2.6e-12 47.4 3.1 4.4e-12 46.6 3.1 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SpoVS PF04232.12 KEY68717.1 - 0.12 12.2 0.1 41 4.0 0.0 3.2 3 0 0 3 3 3 0 Stage V sporulation protein S (SpoVS) CbtA PF09490.10 KEY68719.1 - 0.036 13.8 0.2 0.057 13.2 0.2 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF2561 PF10812.8 KEY68719.1 - 0.048 13.7 0.0 0.13 12.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) FtsX PF02687.21 KEY68719.1 - 0.091 13.2 0.3 0.16 12.5 0.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family rhaM PF05336.13 KEY68720.1 - 6.8e-39 132.3 0.4 8e-39 132.0 0.4 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase EGF_2 PF07974.13 KEY68721.1 - 4 7.9 10.0 6.7 7.2 10.0 1.4 1 0 0 1 1 1 0 EGF-like domain Carboxyl_trans PF01039.22 KEY68722.1 - 1e-137 459.8 0.0 1.3e-137 459.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KEY68722.1 - 0.07 12.6 0.3 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 KEY68723.1 - 1.4e-42 145.4 1.3 2.8e-42 144.5 1.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEY68723.1 - 7.1e-32 110.4 0.0 1.6e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEY68723.1 - 2.9e-27 94.7 0.2 5.3e-27 93.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEY68723.1 - 1.7e-13 51.0 0.1 3.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEY68723.1 - 4.2e-06 26.6 0.1 8.8e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.6 KEY68724.1 - 2.5e-54 184.3 0.0 3.7e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY68724.1 - 6.3e-37 126.9 0.0 8.7e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY68724.1 - 1.3e-11 44.8 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEY68724.1 - 0.13 11.6 0.0 11 5.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 KEY68726.1 - 0.0046 16.8 2.1 0.0056 16.5 0.8 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) PHD PF00628.29 KEY68729.1 - 1.1e-08 34.8 1.6 1.1e-08 34.8 1.6 1.8 2 0 0 2 2 2 1 PHD-finger UIM PF02809.20 KEY68729.1 - 0.0044 16.8 2.6 0.019 14.9 2.6 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.6 KEY68729.1 - 0.0065 16.0 2.2 0.011 15.3 2.2 1.4 1 0 0 1 1 1 1 PHD-finger CEBP_ZZ PF16366.5 KEY68729.1 - 0.071 13.4 0.7 0.15 12.3 0.7 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain MMR_HSR1 PF01926.23 KEY68730.1 - 1.6e-13 50.7 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY68730.1 - 4.6e-06 26.6 0.0 9.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KEY68730.1 - 0.0019 17.7 0.1 0.0048 16.4 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEY68730.1 - 0.0055 16.8 0.0 2.1 8.3 0.0 2.4 1 1 0 2 2 2 2 Dynamin family Roc PF08477.13 KEY68730.1 - 0.019 15.2 0.3 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KEY68730.1 - 0.02 15.4 0.1 0.054 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEY68730.1 - 0.036 14.4 0.9 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 KEY68730.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KEY68730.1 - 0.067 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY68730.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MCM PF00493.23 KEY68730.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain HCO3_cotransp PF00955.21 KEY68731.1 - 3.5e-71 240.6 11.9 4.1e-40 138.1 0.2 2.0 1 1 1 2 2 2 2 HCO3- transporter family YjcB PF15940.5 KEY68731.1 - 1.6 9.0 5.7 2 8.6 0.6 3.0 2 1 0 2 2 2 0 Family of unknown function ADH_zinc_N PF00107.26 KEY68732.1 - 1.2e-14 54.4 0.1 2e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68732.1 - 0.00042 21.4 0.0 0.00076 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY68732.1 - 0.0025 17.7 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PI3Ka PF00613.20 KEY68734.1 - 1.8e-57 193.8 0.2 2.9e-57 193.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KEY68734.1 - 3.1e-46 158.2 0.1 9.5e-32 110.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KEY68734.1 - 2.9e-31 108.2 0.0 4.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 KEY68734.1 - 0.0022 18.3 0.0 0.0091 16.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain DUF4336 PF14234.6 KEY68735.1 - 1.9e-15 56.9 0.1 7.3e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 KEY68737.1 - 7.9e-34 115.8 0.0 1.6e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KEY68737.1 - 3.8e-18 65.3 3.2 3e-17 62.5 1.4 3.1 2 1 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Arg_decarb_HB PF17810.1 KEY68737.1 - 0.065 13.5 0.0 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain PBP1_TM PF14812.6 KEY68737.1 - 3.9 7.9 22.8 0.63 10.5 0.7 3.5 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 KEY68738.1 - 4.8e-06 25.8 0.1 7.8e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68738.1 - 0.0032 17.6 1.5 0.0032 17.6 1.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_C PF00137.21 KEY68740.1 - 4e-29 100.7 31.9 5e-18 65.2 11.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 KEY68741.1 - 3.3e-77 259.8 0.0 1.6e-76 257.5 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KEY68741.1 - 2.9e-42 144.0 0.0 6.9e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KEY68741.1 - 1.2e-33 116.9 0.0 2.2e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KEY68741.1 - 8.2e-16 57.8 0.1 1.6e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KEY68741.1 - 0.0041 16.9 0.9 0.014 15.2 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Pal1 PF08316.11 KEY68743.1 - 7.1e-46 156.4 2.4 1.9e-45 155.0 2.4 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Sigma70_ECF PF07638.11 KEY68743.1 - 0.49 10.3 2.7 0.82 9.5 2.7 1.3 1 0 0 1 1 1 0 ECF sigma factor Flavoprotein PF02441.19 KEY68744.1 - 3.6e-43 147.0 0.0 7e-43 146.1 0.0 1.4 1 1 0 1 1 1 1 Flavoprotein Med24_N PF11277.8 KEY68745.1 - 0.12 10.4 1.2 0.16 10.0 1.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF4646 PF15496.6 KEY68745.1 - 0.13 12.8 0.0 0.45 11.1 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) SR-25 PF10500.9 KEY68745.1 - 1.2 8.7 9.6 2.3 7.8 9.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.18 KEY68746.1 - 6.3e-46 156.7 0.0 1.1e-45 155.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KEY68746.1 - 0.00052 19.7 0.3 0.19 11.7 0.3 3.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEY68746.1 - 0.0075 15.7 1.0 1.2 8.9 0.7 3.4 3 0 0 3 3 3 1 EF hand GRAM PF02893.20 KEY68746.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 GRAM domain EF-hand_7 PF13499.6 KEY68746.1 - 0.12 12.8 2.6 0.49 10.9 0.4 3.0 3 1 2 5 5 5 0 EF-hand domain pair Pkinase PF00069.25 KEY68747.1 - 8.5e-64 215.5 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68747.1 - 6.4e-32 110.8 0.0 8.1e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY68747.1 - 8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEY68747.1 - 0.0028 17.6 0.2 0.029 14.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEY68747.1 - 0.044 12.8 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KEY68747.1 - 0.056 12.2 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KEY68747.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Exo_endo_phos PF03372.23 KEY68748.1 - 0.0013 18.3 0.0 0.0052 16.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 KEY68749.1 - 2.5e-26 92.6 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68749.1 - 7e-14 51.7 0.0 9.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY68749.1 - 4.2e-09 35.7 0.0 6.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEY68749.1 - 0.00019 21.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C1_2 PF03051.15 KEY68753.1 - 2.5e-151 504.4 0.0 2.9e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KEY68753.1 - 1.6e-06 28.4 0.1 0.007 16.5 0.0 2.4 2 1 0 2 2 2 2 Papain family cysteine protease eIF-5a PF01287.20 KEY68754.1 - 5.1e-06 26.5 0.0 9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 KEY68754.1 - 0.0025 18.5 7.2 0.059 14.0 0.5 2.4 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red NFACT-C PF11923.8 KEY68755.1 - 7.8e-41 138.3 0.3 7.8e-41 138.3 0.3 3.5 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 KEY68755.1 - 5.1e-35 121.1 7.4 5.1e-35 121.1 7.4 1.8 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KEY68755.1 - 1.5e-32 112.4 0.0 3.1e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain Annexin PF00191.20 KEY68756.1 - 1.5e-18 66.6 0.7 2.8e-05 24.1 0.0 4.5 4 0 0 4 4 4 4 Annexin CDC45 PF02724.14 KEY68756.1 - 5.3 5.2 11.3 8.3 4.6 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_32 PF13679.6 KEY68757.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEY68758.1 - 1.1e-22 80.6 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68758.1 - 6.1e-12 46.1 0.0 2e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY68758.1 - 3.1e-11 43.8 0.0 6.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68758.1 - 4.8e-09 36.2 0.0 1.9e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY68758.1 - 1.3e-08 35.5 0.0 3.2e-07 31.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KEY68758.1 - 0.00051 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEY68758.1 - 0.0024 17.4 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KEY68758.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KEY68758.1 - 0.059 12.7 0.0 0.57 9.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEY68758.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KEY68758.1 - 0.085 12.1 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KEY68758.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KEY68759.1 - 2.1e-23 82.7 0.0 3.3e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain ketoacyl-synt PF00109.26 KEY68760.1 - 2.7e-62 210.6 0.5 6.7e-35 120.9 1.3 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY68760.1 - 1.5e-51 174.8 0.1 3.4e-51 173.7 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KEY68760.1 - 7.7e-50 170.2 0.2 1.3e-49 169.5 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY68760.1 - 1.6e-42 145.8 0.0 4.7e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY68760.1 - 1.3e-30 105.9 0.3 2.7e-30 104.8 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY68760.1 - 4.7e-18 65.7 0.0 2.2e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEY68760.1 - 2.6e-14 53.1 0.0 6.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase SAT PF16073.5 KEY68760.1 - 0.00013 21.7 0.5 0.0068 16.2 0.5 2.3 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_zinc_N PF00107.26 KEY68760.1 - 0.00017 21.5 0.1 0.00083 19.3 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEY68760.1 - 0.00099 19.4 0.0 0.0044 17.4 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KEY68760.1 - 0.0028 18.7 0.0 0.88 10.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.7 KEY68760.1 - 0.038 14.6 0.1 0.31 11.6 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thiolase_N PF00108.23 KEY68760.1 - 0.055 12.8 0.4 0.1 12.0 0.4 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 KEY68761.1 - 2.4e-29 102.4 49.4 2.7e-28 98.9 48.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KEY68762.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KEY68762.1 - 3.8e-05 23.3 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KEY68762.1 - 0.0018 18.0 0.1 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KEY68762.1 - 0.054 13.4 0.2 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 KEY68762.1 - 0.058 13.6 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family DUF829 PF05705.14 KEY68763.1 - 2.5e-50 171.7 0.0 2.8e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 KEY68763.1 - 0.1 12.2 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Polyketide_cyc2 PF10604.9 KEY68764.1 - 0.058 13.7 0.2 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Dabb PF07876.12 KEY68765.1 - 2.2e-11 44.2 0.0 2.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HATPase_c PF02518.26 KEY68766.1 - 2.5e-22 79.5 0.0 5.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY68766.1 - 3.4e-17 62.6 2.0 1.5e-12 47.6 0.0 3.4 4 0 0 4 4 4 2 Response regulator receiver domain PAS_9 PF13426.7 KEY68766.1 - 2.3e-13 50.3 0.0 1.6e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KEY68766.1 - 7.4e-11 42.0 0.0 0.0012 18.8 0.0 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KEY68766.1 - 5.8e-09 36.2 0.2 0.028 14.7 0.0 5.0 4 1 0 4 4 4 2 PAS fold HisKA PF00512.25 KEY68766.1 - 6.5e-09 35.7 0.6 3.5e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KEY68766.1 - 2.7e-07 30.8 0.1 0.0035 17.6 0.0 4.4 3 2 1 4 4 4 2 PAS fold PAS_8 PF13188.7 KEY68766.1 - 1.7e-06 27.9 0.0 0.0057 16.7 0.0 3.7 3 0 0 3 3 3 2 PAS domain Mpv17_PMP22 PF04117.12 KEY68768.1 - 1.1e-12 48.0 1.8 1.1e-12 48.0 1.8 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KEY68768.1 - 0.12 12.6 3.1 0.37 11.0 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) YIF1 PF03878.15 KEY68769.1 - 3.2e-98 328.0 0.9 3.7e-98 327.8 0.9 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KEY68769.1 - 0.38 10.5 13.6 0.21 11.3 11.3 1.6 1 1 1 2 2 2 0 Yip1 domain SRP-alpha_N PF04086.13 KEY68770.1 - 2.3e-80 270.6 0.1 3.1e-80 270.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KEY68770.1 - 4.7e-53 179.8 0.2 8.2e-53 179.0 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KEY68770.1 - 6.5e-09 35.9 0.2 2.1e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KEY68770.1 - 1.8e-05 23.9 0.0 3.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KEY68770.1 - 0.00052 19.8 0.2 0.0014 18.4 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEY68770.1 - 0.002 18.6 0.4 0.0067 16.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEY68770.1 - 0.016 14.8 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEY68770.1 - 0.027 14.6 0.0 0.095 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KEY68770.1 - 0.028 14.5 0.4 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KEY68770.1 - 0.03 14.4 0.3 0.16 12.0 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY68770.1 - 0.07 13.5 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KEY68770.1 - 0.07 13.6 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SMC_N PF02463.19 KEY68770.1 - 0.074 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KEY68770.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hamartin PF04388.12 KEY68770.1 - 0.12 11.1 4.0 0.16 10.6 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein Mid2 PF04478.12 KEY68773.1 - 0.00022 21.1 0.0 0.00074 19.4 0.0 2.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor FAM176 PF14851.6 KEY68773.1 - 0.011 15.4 7.2 0.36 10.5 0.5 3.2 2 1 1 3 3 3 0 FAM176 family SKG6 PF08693.10 KEY68773.1 - 0.021 14.2 1.8 0.021 14.2 1.8 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TMEM100 PF16311.5 KEY68773.1 - 0.16 11.6 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 Mitofilin PF09731.9 KEY68773.1 - 0.76 8.5 5.8 1 8.2 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MPM1 PF17234.2 KEY68773.1 - 0.95 9.7 7.8 1.5 9.0 6.1 2.3 1 1 1 2 2 2 0 Mitochondrial peculiar membrane protein 1 CDC27 PF09507.10 KEY68773.1 - 1.3 8.3 16.5 1.8 7.8 16.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 KEY68773.1 - 2.3 6.8 7.9 2.7 6.5 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RicinB_lectin_2 PF14200.6 KEY68774.1 - 0.012 16.3 0.1 0.071 13.8 0.0 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like PI-PLC-X PF00388.19 KEY68775.1 - 5.8e-55 184.9 0.0 1.1e-54 184.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEY68775.1 - 2.2e-39 134.3 0.2 4.6e-39 133.3 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Cupin_7 PF12973.7 KEY68776.1 - 0.04 13.8 0.0 0.093 12.7 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain APH PF01636.23 KEY68777.1 - 2.1e-17 63.9 0.0 7.9e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_10 PF13673.7 KEY68779.1 - 2.3e-08 34.0 0.0 8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY68779.1 - 1.8e-06 28.0 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY68779.1 - 4.5e-06 27.0 0.0 7.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY68779.1 - 3.3e-05 24.1 0.0 6.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KEY68779.1 - 0.00049 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY68779.1 - 0.00093 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KEY68779.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DLH PF01738.18 KEY68780.1 - 1.7e-17 63.7 0.1 1.9e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEY68780.1 - 0.036 13.5 0.1 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY68780.1 - 0.075 13.6 0.0 0.096 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ACPS PF01648.20 KEY68781.1 - 1.3e-09 38.2 0.0 2.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.13 KEY68783.1 - 1.4e-58 198.7 3.8 5.8e-37 127.8 0.4 2.3 2 1 0 2 2 2 2 Signal peptide peptidase Pro_isomerase PF00160.21 KEY68784.1 - 5.6e-53 179.4 0.0 7e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transposase_22 PF02994.14 KEY68785.1 - 0.12 12.5 0.4 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 L1 transposable element RBD-like domain zf_UBZ PF18439.1 KEY68785.1 - 0.31 10.7 2.2 1.9 8.2 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KEY68785.1 - 1.3 8.6 7.8 0.15 11.6 3.1 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Apt1 PF10351.9 KEY68785.1 - 3.5 6.4 11.7 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Acetyltransf_1 PF00583.25 KEY68786.1 - 0.00046 20.4 0.0 0.00065 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_transf_8C PF08437.10 KEY68786.1 - 4.1 7.5 5.4 2.2 8.4 0.1 2.8 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal Hexokinase_2 PF03727.16 KEY68787.1 - 2.7e-76 256.2 0.0 4e-76 255.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEY68787.1 - 2.7e-75 252.7 0.0 3.9e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase YhdB PF14148.6 KEY68787.1 - 0.14 12.3 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 YhdB-like protein HSP70 PF00012.20 KEY68788.1 - 7.6e-11 40.9 0.2 2.3e-09 36.0 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KEY68788.1 - 0.036 12.9 0.1 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Thaumatin PF00314.17 KEY68789.1 - 3.5e-68 229.4 4.6 4.5e-68 229.1 4.6 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KEY68789.1 - 0.011 15.1 0.2 0.5 9.6 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase Ank_2 PF12796.7 KEY68790.1 - 2.4e-11 44.1 0.2 1.2e-05 25.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY68790.1 - 1e-07 31.6 0.4 0.049 14.2 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KEY68790.1 - 2.9e-07 30.9 0.7 0.0005 20.6 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY68790.1 - 2.9e-05 24.2 0.3 0.89 10.0 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY68790.1 - 0.00051 20.4 0.3 0.58 10.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat TFIIS_C PF01096.18 KEY68791.1 - 3.7e-19 68.3 2.0 3.7e-19 68.3 2.0 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KEY68791.1 - 8.9e-08 31.9 3.3 4.6e-07 29.6 0.2 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Desulfoferrod_N PF06397.12 KEY68791.1 - 0.0012 18.4 1.9 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 KEY68791.1 - 0.0088 16.0 6.4 0.054 13.5 0.4 2.6 2 1 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KEY68791.1 - 0.0097 15.8 7.4 3.1 7.8 0.1 3.9 4 0 0 4 4 4 1 zinc-ribbon domain IBR PF01485.21 KEY68791.1 - 0.013 15.7 5.6 1.9 8.8 0.2 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_ribbon_recom PF13408.6 KEY68791.1 - 0.48 11.0 2.8 1.8 9.1 0.1 2.5 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 KEY68791.1 - 1 9.4 5.1 0.46 10.5 0.4 2.2 2 1 0 2 2 2 0 zinc-ribbons Med31 PF05669.12 KEY68792.1 - 1.8e-37 127.2 3.0 2.2e-37 127.0 3.0 1.0 1 0 0 1 1 1 1 SOH1 Metallophos PF00149.28 KEY68793.1 - 3.9e-10 40.6 0.0 5.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY68793.1 - 7.7e-10 39.2 0.0 5.7e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldolase_II PF00596.21 KEY68793.1 - 0.013 15.5 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain CFEM PF05730.11 KEY68794.1 - 2.7e-10 40.2 8.4 5.6e-10 39.2 8.4 1.6 1 0 0 1 1 1 1 CFEM domain DUF4614 PF15391.6 KEY68794.1 - 0.049 13.6 14.2 0.072 13.1 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1641 PF07849.11 KEY68794.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) RIFIN PF02009.16 KEY68794.1 - 2.4 7.9 4.8 2.9 7.7 4.8 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 KEY68794.1 - 3.9 5.9 4.8 4.2 5.8 4.8 1.1 1 0 0 1 1 1 0 Macoilin family GPI2 PF06432.11 KEY68795.1 - 1.5e-132 441.3 1.4 1.7e-132 441.0 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_1 PF00561.20 KEY68796.1 - 6.1e-16 58.8 0.5 1.4e-14 54.4 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY68796.1 - 4.2e-12 47.2 3.9 5.5e-12 46.8 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY68796.1 - 1.9e-11 43.7 0.0 3.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KEY68796.1 - 1.1e-05 25.1 0.1 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 KEY68796.1 - 0.00041 20.1 0.2 0.0056 16.4 0.2 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KEY68796.1 - 0.00042 20.0 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KEY68796.1 - 0.00052 19.6 0.2 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KEY68796.1 - 0.0012 17.6 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF2048 PF09752.9 KEY68796.1 - 0.0074 15.4 0.0 0.0094 15.1 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Esterase PF00756.20 KEY68796.1 - 0.013 15.2 0.4 0.023 14.3 0.4 1.7 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KEY68796.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NICE-3 PF07406.11 KEY68797.1 - 0.18 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 NICE-3 protein 2-Hacid_dh_C PF02826.19 KEY68798.1 - 3.3e-43 147.1 0.0 2.9e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 KEY68799.1 - 6e-09 36.4 14.8 0.0016 19.2 0.1 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KEY68799.1 - 7e-07 28.8 10.2 1.5e-06 27.7 10.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KEY68799.1 - 0.0094 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KEY68799.1 - 0.038 14.3 5.5 0.092 13.1 5.5 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.26 KEY68800.1 - 9.1e-48 161.5 0.0 1e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY68800.1 - 0.00042 20.0 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEY68800.1 - 0.0053 16.6 0.1 0.0097 15.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KEY68800.1 - 0.062 13.6 0.1 0.088 13.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.12 KEY68801.1 - 4.3e-18 65.6 1.8 5.3e-18 65.3 1.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SSM_b PF10741.9 KEY68801.1 - 0.043 13.6 0.3 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF2408 PF10303.9 KEY68801.1 - 0.2 12.3 1.3 0.3 11.6 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) NAC PF01849.18 KEY68802.1 - 2.1e-23 82.0 0.1 9.3e-23 80.0 0.0 2.0 2 0 0 2 2 2 1 NAC domain DUF3246 PF11596.8 KEY68802.1 - 0.076 12.4 4.9 0.079 12.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PGA2 PF07543.12 KEY68802.1 - 0.17 11.9 11.0 1.5 8.8 4.6 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Cwf_Cwc_15 PF04889.12 KEY68802.1 - 0.43 10.3 15.3 0.82 9.4 7.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L14e PF01929.17 KEY68803.1 - 6.7e-28 97.0 3.0 9.1e-28 96.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KEY68803.1 - 0.00096 19.0 0.4 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 KOW motif DUF1687 PF07955.11 KEY68805.1 - 2.2e-31 109.0 0.0 3.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Cuticle_4 PF15955.5 KEY68806.1 - 2.6 8.8 12.4 0.41 11.4 2.8 4.6 3 0 0 3 3 3 0 Cuticle protein L51_S25_CI-B8 PF05047.16 KEY68807.1 - 4.4e-14 52.1 0.0 5.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 KEY68808.1 - 2.4e-47 159.6 1.1 3.4e-47 159.2 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2207 PF09972.9 KEY68808.1 - 0.022 13.5 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MtN3_slv PF03083.16 KEY68808.1 - 0.065 13.3 0.4 0.11 12.5 0.4 1.4 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TadE PF07811.12 KEY68808.1 - 0.093 13.0 0.1 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 TadE-like protein CNH PF00780.22 KEY68809.1 - 1.6e-62 211.6 0.0 2.4e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KEY68809.1 - 3.4e-35 121.9 0.2 5.5e-35 121.2 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KEY68809.1 - 1e-11 45.1 2.6 1.9e-11 44.2 0.0 2.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KEY68809.1 - 0.00033 21.1 0.0 0.025 15.1 0.0 3.2 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 KEY68809.1 - 0.0022 17.8 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 2 PH domain Sod_Cu PF00080.20 KEY68810.1 - 7.9e-46 155.8 4.9 9.4e-46 155.5 4.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Lyase_1 PF00206.20 KEY68811.1 - 5e-111 371.0 0.0 7.2e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KEY68811.1 - 3.7e-22 78.5 0.1 9.1e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus SNase PF00565.17 KEY68812.1 - 9.7e-70 231.9 1.6 8.3e-19 68.1 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KEY68812.1 - 1.8e-21 76.4 0.0 3.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KEY68812.1 - 2.3e-05 23.8 0.0 5.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TAL_FSA PF00923.19 KEY68813.1 - 5.2e-95 318.1 0.2 6e-95 317.9 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 KEY68813.1 - 0.017 14.6 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_67M PF07488.12 KEY68813.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Metallophos PF00149.28 KEY68814.1 - 7.4e-13 49.5 0.0 1.3e-12 48.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY68814.1 - 7.3e-07 29.5 0.1 1.7e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Pet191_N PF10203.9 KEY68815.1 - 2.6e-27 94.9 5.9 3.3e-27 94.6 5.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KEY68815.1 - 0.03 14.2 0.4 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 KEY68815.1 - 0.053 13.3 0.7 0.1 12.4 0.7 1.4 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 KEY68815.1 - 0.16 12.0 10.1 0.44 10.6 1.0 3.0 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KEY68815.1 - 0.32 11.1 5.2 3.8 7.6 1.9 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_1 PF00561.20 KEY68816.1 - 3.3e-24 85.9 0.3 1.1e-23 84.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KEY68816.1 - 5e-23 80.4 0.1 1.1e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KEY68816.1 - 2.9e-06 26.7 0.0 0.00038 19.8 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KEY68816.1 - 2.7e-05 23.9 0.1 0.03 14.0 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Vta1 PF04652.16 KEY68816.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Vta1 like RTA1 PF04479.13 KEY68817.1 - 7.2e-66 221.7 3.1 7.2e-66 221.7 3.1 1.6 1 1 1 2 2 2 1 RTA1 like protein zf-CCCH PF00642.24 KEY68818.1 - 0.00098 19.0 0.3 0.0019 18.1 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 KEY68818.1 - 0.29 10.9 3.0 0.49 10.2 3.0 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Myosin_head PF00063.21 KEY68819.1 - 9.8e-268 889.9 1.0 1.7e-267 889.1 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KEY68819.1 - 3.8e-12 45.8 0.2 1.1e-11 44.3 0.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KEY68819.1 - 1.1e-10 40.1 278.4 4.5e-10 38.1 52.9 7.4 3 2 4 8 8 8 4 Myosin tail AAA_22 PF13401.6 KEY68819.1 - 0.026 14.8 0.0 0.026 14.8 0.0 5.0 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 KEY68819.1 - 0.072 12.8 5.1 4.3 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Chorismate_synt PF01264.21 KEY68820.1 - 1.3e-138 461.2 0.0 1.5e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF2786 PF10979.8 KEY68820.1 - 0.51 10.3 2.6 0.32 10.9 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DDE_1 PF03184.19 KEY68826.1 - 1.9e-08 34.2 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KEY68826.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CHAT PF12770.7 KEY68827.1 - 5.9e-12 45.6 0.6 8.5e-12 45.1 0.6 1.2 1 0 0 1 1 1 1 CHAT domain ZZ PF00569.17 KEY68828.1 - 5.5e-10 38.9 5.4 1e-09 38.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KEY68828.1 - 0.077 13.3 10.1 0.18 12.1 10.1 1.6 1 0 0 1 1 1 0 C1 domain Actin_micro PF17003.5 KEY68830.1 - 0.098 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative actin-like family Epimerase PF01370.21 KEY68831.1 - 1.9e-11 43.9 0.3 3.9e-11 42.9 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEY68831.1 - 2.3e-06 27.2 0.6 4.1e-05 23.1 0.2 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KEY68831.1 - 2.1e-05 23.8 0.1 0.0034 16.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KEY68831.1 - 0.00015 21.0 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEY68831.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KEY68831.1 - 0.00025 21.0 0.2 0.0005 20.0 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY68831.1 - 0.00045 20.2 5.3 0.0053 16.7 5.3 2.6 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KEY68831.1 - 0.00058 20.4 0.1 0.0025 18.4 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KEY68831.1 - 0.012 15.1 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 KEY68831.1 - 0.03 13.9 0.7 0.068 12.7 0.7 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KEY68831.1 - 0.04 13.5 0.1 0.092 12.3 0.1 1.6 1 1 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.15 KEY68831.1 - 0.065 13.4 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pilin_PilX PF11530.8 KEY68831.1 - 0.2 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 Minor type IV pilin, PilX An_peroxidase PF03098.15 KEY68832.1 - 0.0019 16.9 0.0 0.0025 16.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase LysM PF01476.20 KEY68834.1 - 9e-16 57.7 0.0 1e-05 25.5 0.0 4.2 4 0 0 4 4 4 2 LysM domain DUF3439 PF11921.8 KEY68834.1 - 0.52 10.3 3.9 1.6 8.7 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 KEY68835.1 - 4.1e-49 168.0 4.9 1.7e-48 166.0 4.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY68835.1 - 1e-07 32.3 14.8 1e-07 32.3 14.8 4.6 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.20 KEY68837.1 - 4.6e-12 45.8 0.0 0.011 15.8 0.0 4.4 4 0 0 4 4 4 4 LysM domain NLPC_P60 PF00877.19 KEY68837.1 - 0.00063 19.7 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 2 NlpC/P60 family HTH_23 PF13384.6 KEY68837.1 - 0.0028 17.4 0.0 2.7 7.9 0.0 2.9 3 0 0 3 3 3 2 Homeodomain-like domain LRV_FeS PF05484.11 KEY68837.1 - 0.011 15.7 0.0 34 4.5 0.0 3.5 3 0 0 3 3 3 0 LRV protein FeS4 cluster CarbpepA_inh PF02977.15 KEY68837.1 - 1.3 8.9 8.7 6.7 6.6 0.1 4.3 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor Kunitz_legume PF00197.18 KEY68840.1 - 0.049 13.6 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Trypsin and protease inhibitor PAF-AH_p_II PF03403.13 KEY68842.1 - 1.7e-11 43.3 0.0 1.6e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KEY68842.1 - 0.00038 19.8 0.3 0.0011 18.3 0.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY68842.1 - 0.0022 17.7 0.7 0.031 13.9 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KEY68842.1 - 0.061 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KEY68842.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KEY68842.1 - 0.15 11.9 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family GMC_oxred_N PF00732.19 KEY68843.1 - 7.5e-26 91.2 0.2 3.1e-11 43.2 0.0 3.3 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY68843.1 - 0.0043 17.2 0.1 0.01 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68843.1 - 0.03 13.9 0.2 0.28 10.7 0.2 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY68843.1 - 0.039 13.2 0.0 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY68845.1 - 4e-14 52.6 0.4 1.7e-06 27.5 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY68845.1 - 2.5e-05 24.4 0.1 8.9e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY68845.1 - 0.00096 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY68845.1 - 0.0026 17.0 0.0 0.072 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase BCS1_N PF08740.11 KEY68846.1 - 3.1e-28 99.0 0.8 5.8e-28 98.1 0.8 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KEY68846.1 - 2.4e-18 66.8 0.0 5.8e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEY68846.1 - 0.00036 20.3 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEY68846.1 - 0.007 16.4 0.0 0.059 13.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KEY68846.1 - 0.023 14.5 0.2 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEY68846.1 - 0.025 15.0 2.4 0.041 14.3 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KEY68846.1 - 0.027 13.8 0.3 0.077 12.3 0.0 1.8 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 KEY68846.1 - 0.053 13.9 0.0 0.7 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KEY68846.1 - 0.084 13.2 0.0 0.6 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.13 KEY68846.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain UbiA PF01040.18 KEY68847.1 - 1.6e-28 99.7 18.6 2.8e-28 98.9 18.6 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family IDO PF01231.18 KEY68848.1 - 1.1e-147 492.3 0.0 1.3e-147 492.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KEY68848.1 - 0.055 12.2 0.0 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Birna_VP3 PF01767.16 KEY68848.1 - 0.23 11.5 0.0 0.37 10.9 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein Aminotran_5 PF00266.19 KEY68849.1 - 3.2e-09 36.2 0.0 3.8e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V p450 PF00067.22 KEY68850.1 - 7.7e-46 156.8 0.0 2.1e-45 155.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Metallophos PF00149.28 KEY68851.1 - 1.4e-15 58.4 0.0 3.3e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY68851.1 - 1.2e-06 28.8 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain BspA_v PF18220.1 KEY68851.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 Adhesin BspA variable domain RTA1 PF04479.13 KEY68852.1 - 4.4e-53 180.0 10.0 4.4e-53 180.0 10.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF751 PF05421.11 KEY68852.1 - 0.3 11.9 8.4 0.68 10.7 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF751) Zn_clus PF00172.18 KEY68853.1 - 3e-08 33.6 7.4 6.7e-08 32.5 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.15 KEY68854.1 - 4.3e-30 105.2 9.2 1.4e-22 80.5 3.4 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase Glu_synthase PF01645.17 KEY68854.1 - 5.2e-08 32.4 0.1 7.7e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY68854.1 - 3e-06 26.5 1.2 1.7e-05 24.0 1.2 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY68854.1 - 8.6e-05 21.7 1.7 0.00014 21.0 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Ribosomal_L31 PF01197.18 KEY68854.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31 Sugar_tr PF00083.24 KEY68855.1 - 1.3e-108 363.8 17.2 1.5e-108 363.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68855.1 - 1.5e-20 73.4 51.9 3.5e-18 65.7 26.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KEY68856.1 - 2.6e-45 154.3 0.0 3.4e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68856.1 - 1.1e-26 93.9 0.0 1.5e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68856.1 - 3.6e-07 30.3 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY68856.1 - 0.0003 20.2 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY68856.1 - 0.0004 19.9 0.1 0.00089 18.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY68856.1 - 0.018 14.9 0.4 0.027 14.4 0.1 1.5 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEY68856.1 - 0.081 12.0 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 KEY68857.1 - 6.8e-13 49.1 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEY68857.1 - 3e-07 30.9 0.2 6.7e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEY68857.1 - 8.5e-06 25.9 0.1 1.3e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEY68857.1 - 0.00035 20.6 0.3 0.005 16.8 0.3 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KEY68857.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEY68857.1 - 0.0037 16.9 0.1 0.012 15.3 0.1 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEY68857.1 - 0.0037 17.2 0.3 0.009 15.9 0.1 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KEY68859.1 - 1.1e-35 123.3 43.3 1.6e-26 93.1 40.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KEY68859.1 - 0.0011 17.9 0.0 0.0011 17.9 0.0 2.3 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF412 PF04217.13 KEY68859.1 - 1.5 8.7 5.4 9.2 6.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Ceramidase PF05875.12 KEY68860.1 - 8.1e-60 202.5 6.5 9e-60 202.3 6.5 1.0 1 0 0 1 1 1 1 Ceramidase VCBS PF13517.6 KEY68861.1 - 0.0077 16.8 0.4 3.4 8.3 0.0 2.2 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella VCBS PF13517.6 KEY68862.1 - 3.3e-07 30.8 0.0 0.0004 20.9 0.0 1.8 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HET PF06985.11 KEY68862.1 - 0.017 15.4 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY68863.1 - 0.00049 20.5 0.0 0.00057 20.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KEY68864.1 - 5.2e-07 29.7 13.7 8.9e-07 28.9 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY68864.1 - 0.022 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPP_enzyme_N PF02776.18 KEY68865.1 - 1.3e-38 132.3 0.2 8.5e-37 126.4 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY68865.1 - 1.6e-23 82.9 0.0 3.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEY68865.1 - 7.5e-23 81.0 0.1 1.1e-21 77.2 0.0 2.7 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KEY68865.1 - 0.022 14.5 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ldh_1_N PF00056.23 KEY68866.1 - 3.5e-27 95.2 0.3 5e-27 94.7 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEY68866.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 KEY68866.1 - 0.0019 17.8 1.6 0.017 14.7 0.9 2.4 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KEY68866.1 - 0.0031 16.9 0.8 0.015 14.7 0.2 2.1 2 0 0 2 2 2 1 ThiF family Glyco_hydro_4 PF02056.16 KEY68866.1 - 0.005 16.4 0.1 0.025 14.1 0.0 2.0 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase ApbA PF02558.16 KEY68866.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PPDK_N PF01326.19 KEY68867.1 - 4.5e-112 374.5 0.0 6.9e-112 373.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 KEY68867.1 - 1.6e-61 208.0 0.0 2.4e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 KEY68867.1 - 3.6e-24 84.3 0.9 4e-23 80.9 0.7 2.5 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain bZIP_2 PF07716.15 KEY68869.1 - 0.02 14.9 4.7 0.047 13.8 4.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.16 KEY68870.1 - 1e-14 54.3 11.1 1.2e-14 54.0 11.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68870.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Tautomerase_3 PF14832.6 KEY68871.1 - 3.3e-49 166.6 0.6 3.7e-49 166.5 0.6 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.21 KEY68872.1 - 2.9e-13 49.8 0.0 1.2e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY68872.1 - 2e-09 37.6 0.0 8.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEY68872.1 - 6.5e-08 32.4 0.1 1.5e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY68872.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY68872.1 - 9.5e-06 25.0 0.0 6.1e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KEY68872.1 - 0.00043 19.5 0.0 0.001 18.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KEY68872.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Ldh_1_N PF00056.23 KEY68872.1 - 0.0039 17.3 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KEY68872.1 - 0.011 15.1 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Zn_clus PF00172.18 KEY68873.1 - 3e-08 33.6 6.7 3e-08 33.6 6.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY68873.1 - 1.1e-07 31.1 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM199X PF15814.5 KEY68874.1 - 5.1 6.0 9.0 5.6 5.9 9.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Methyltransf_2 PF00891.18 KEY68876.1 - 1.9e-20 73.1 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR PF01047.22 KEY68876.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KEY68876.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KEY68876.1 - 0.018 15.4 0.0 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.20 KEY68876.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF5527 PF17665.1 KEY68877.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF732 PF05305.14 KEY68877.1 - 0.052 13.9 0.2 0.088 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Transket_pyr PF02779.24 KEY68878.1 - 6.5e-32 110.6 0.1 1e-31 110.0 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEY68878.1 - 6.4e-09 35.7 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain eIF-1a PF01176.19 KEY68878.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Aldo_ket_red PF00248.21 KEY68879.1 - 2.3e-41 141.9 0.0 5.2e-40 137.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldedh PF00171.22 KEY68880.1 - 1e-68 232.0 0.2 1.1e-42 146.1 0.3 3.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family AAA_7 PF12775.7 KEY68880.1 - 0.14 11.6 0.1 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Peptidase_S8 PF00082.22 KEY68882.1 - 3.2e-27 95.6 13.6 1.8e-26 93.1 13.5 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY68882.1 - 4.9e-09 36.7 0.0 8.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.25 KEY68883.1 - 1.4e-14 54.3 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY68883.1 - 2.6e-11 43.6 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY68883.1 - 4.2e-09 36.7 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY68883.1 - 2e-06 27.7 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KEY68883.1 - 7e-06 26.8 0.0 7.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEY68883.1 - 3.4e-05 24.0 0.0 5.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY68883.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KEY68883.1 - 0.085 12.5 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 KEY68884.1 - 2.7e-25 88.8 0.3 4.9e-25 88.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68884.1 - 1.8e-14 55.0 0.1 3.4e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY68884.1 - 5.2e-08 32.7 0.0 9.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Claudin_2 PF13903.6 KEY68885.1 - 0.037 13.8 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 KEY68885.1 - 0.047 12.5 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sulfolobus_pRN PF05584.11 KEY68885.1 - 0.067 13.2 0.5 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein AAA PF00004.29 KEY68887.1 - 1.9e-20 73.7 0.0 3.5e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY68887.1 - 0.00052 20.0 0.2 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEY68887.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY68887.1 - 0.003 17.9 0.2 0.047 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KEY68887.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KEY68887.1 - 0.053 13.3 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEY68887.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GFA PF04828.14 KEY68888.1 - 5.1e-23 81.2 2.1 7.2e-23 80.7 2.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_31 PF01055.26 KEY68890.1 - 1.4e-112 377.1 0.9 2.1e-112 376.5 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KEY68890.1 - 0.00018 21.7 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KEY68890.1 - 0.00065 20.0 2.3 0.0045 17.3 0.2 3.2 3 1 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.24 KEY68891.1 - 3.2e-79 266.9 27.0 3.9e-79 266.6 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68891.1 - 2.7e-13 49.6 30.0 2.7e-13 49.6 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-B_dimeris PF09026.10 KEY68893.1 - 6.6 7.2 10.2 12 6.3 10.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.25 KEY68894.1 - 6.9e-40 136.6 0.0 9.9e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68894.1 - 1.5e-27 96.7 0.0 2.5e-27 95.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68894.1 - 3e-12 46.8 0.7 1.8e-11 44.3 0.7 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY68894.1 - 2.8e-07 30.3 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY68894.1 - 5.3e-06 25.6 0.1 7.6e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEY68894.1 - 4.2e-05 23.5 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KEY68894.1 - 0.0019 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KEY68894.1 - 0.0042 16.5 0.2 0.0084 15.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KEY68894.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KEY68894.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KEY68894.1 - 0.06 12.5 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.18 KEY68894.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KEY68894.1 - 0.13 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KEY68894.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KEY68894.1 - 0.18 11.3 0.3 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Peptidase_M20 PF01546.28 KEY68895.1 - 3.8e-15 56.1 0.4 1.3e-14 54.4 0.4 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ABC2_membrane PF01061.24 KEY68896.1 - 5e-89 297.2 46.9 2.4e-45 154.5 22.2 2.4 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 KEY68896.1 - 1e-36 124.7 0.8 2e-29 101.3 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KEY68896.1 - 1.1e-33 116.6 0.0 4.2e-16 59.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KEY68896.1 - 1.2e-13 51.4 0.7 4.1e-13 49.8 0.7 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY68896.1 - 1.7e-07 31.8 0.3 0.0002 21.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KEY68896.1 - 1.1e-06 28.3 0.0 5.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY68896.1 - 2.7e-05 24.3 0.1 0.013 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY68896.1 - 6.1e-05 23.6 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY68896.1 - 0.0002 21.3 0.0 0.0072 16.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KEY68896.1 - 0.0014 18.6 0.2 1.5 8.7 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 KEY68896.1 - 0.0016 18.9 0.1 0.3 11.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KEY68896.1 - 0.0016 18.3 0.1 1.5 8.6 0.0 2.8 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY68896.1 - 0.0018 18.0 1.1 0.037 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KEY68896.1 - 0.0024 17.3 0.0 10 5.5 0.0 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KEY68896.1 - 0.0026 17.4 0.7 0.17 11.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KEY68896.1 - 0.0034 17.7 0.2 0.63 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY68896.1 - 0.0049 16.6 0.2 2.2 7.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KEY68896.1 - 0.0063 16.9 0.3 3.4 8.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEY68896.1 - 0.012 16.0 0.4 0.59 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KEY68896.1 - 0.055 13.5 0.2 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KEY68896.1 - 0.06 13.8 0.5 0.23 11.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEY68896.1 - 0.064 13.0 0.3 16 5.2 0.1 2.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KEY68896.1 - 0.17 11.6 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zn_clus PF00172.18 KEY68898.1 - 1.4e-08 34.7 9.5 2.5e-08 33.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KEY68899.1 - 1.4e-50 172.4 54.4 1.6e-50 172.2 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY68899.1 - 2.2e-22 79.3 40.8 3.2e-22 78.8 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease AgrD PF05931.11 KEY68899.1 - 0.82 9.7 6.1 0.11 12.5 0.5 2.4 2 0 0 2 2 2 0 Staphylococcal AgrD protein Epiglycanin_C PF14654.6 KEY68899.1 - 1 9.5 8.0 2.7 8.1 0.2 3.1 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Fungal_trans PF04082.18 KEY68900.1 - 3.1e-25 88.7 0.0 7.5e-25 87.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY68900.1 - 2.6e-13 49.9 0.3 4.2e-13 49.2 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68900.1 - 1.3e-12 47.8 0.6 2e-12 47.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY68900.1 - 0.00015 21.3 0.1 0.00031 20.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY68900.1 - 0.00067 18.9 0.5 0.0011 18.2 0.5 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KEY68900.1 - 0.0015 18.1 0.3 0.0027 17.3 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family RskA PF10099.9 KEY68901.1 - 0.0036 17.6 2.4 0.0036 17.6 2.4 1.7 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Podoplanin PF05808.11 KEY68901.1 - 0.0054 16.8 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 KEY68901.1 - 0.0056 16.2 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity PAP1 PF08601.10 KEY68901.1 - 0.007 16.1 0.3 0.007 16.1 0.3 1.5 2 0 0 2 2 2 1 Transcription factor PAP1 Alpha_GJ PF03229.13 KEY68901.1 - 0.011 16.3 5.4 0.015 15.8 4.7 1.6 1 1 0 1 1 1 0 Alphavirus glycoprotein J SKG6 PF08693.10 KEY68901.1 - 0.013 14.9 1.3 0.013 14.9 1.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 KEY68901.1 - 0.021 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Yip1 PF04893.17 KEY68901.1 - 0.048 13.4 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 Yip1 domain TMEM154 PF15102.6 KEY68901.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KEY68901.1 - 0.088 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VSP PF03302.13 KEY68901.1 - 0.099 11.5 0.3 0.18 10.7 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2681 PF10883.8 KEY68901.1 - 0.24 11.8 0.0 0.43 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Mito_fiss_reg PF05308.11 KEY68901.1 - 1.9 8.5 6.4 0.4 10.7 1.3 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Hemerythrin PF01814.23 KEY68902.1 - 4.3e-12 46.8 1.5 6.6e-12 46.2 1.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain WSC PF01822.19 KEY68903.1 - 1.3e-48 163.1 51.7 6.7e-20 71.1 11.3 5.5 6 0 0 6 6 6 3 WSC domain PAN_1 PF00024.26 KEY68903.1 - 5.4e-12 45.5 26.5 0.0001 22.2 0.0 8.0 8 0 0 8 8 8 4 PAN domain PAN_4 PF14295.6 KEY68903.1 - 1.5e-06 28.0 54.9 0.0095 15.8 0.6 8.5 9 0 0 9 9 9 5 PAN domain MANEC PF07502.14 KEY68903.1 - 0.00033 20.8 14.9 0.047 13.9 0.2 5.4 5 0 0 5 5 5 3 MANEC domain Glyco_hydro_61 PF03443.14 KEY68906.1 - 3.4e-05 23.9 0.0 0.05 13.5 0.0 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 KEY68907.1 - 1.9e-08 33.7 0.0 3.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY68907.1 - 2e-07 31.0 12.7 4.2e-07 30.0 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KEY68908.1 - 3.4e-10 40.5 7.6 1.6e-08 35.0 1.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cellulase PF00150.18 KEY68909.1 - 6e-40 137.4 0.0 8.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mucin PF01456.17 KEY68909.1 - 0.06 13.3 10.8 0.11 12.4 10.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Oxysterol_BP PF01237.18 KEY68910.1 - 2.5e-50 171.4 0.1 1.5e-47 162.2 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein adh_short PF00106.25 KEY68911.1 - 1.1e-42 145.8 0.6 1.8e-42 145.1 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68911.1 - 2e-34 119.2 0.2 3.3e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68911.1 - 1.6e-09 37.9 0.2 3.6e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 KR domain Hydrolase_like PF13242.6 KEY68911.1 - 2.4e-07 30.7 0.1 5.6e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY68911.1 - 2.9e-06 27.7 0.0 1.2e-05 25.7 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KEY68912.1 - 7.3e-59 196.3 0.1 9.4e-12 45.4 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY68912.1 - 8.4e-44 147.4 2.8 1.1e-10 41.9 0.1 8.3 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY68912.1 - 3.2e-39 132.5 12.4 2.9e-08 33.8 0.1 10.5 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY68912.1 - 4e-38 125.1 1.7 0.0004 20.6 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 KEY68912.1 - 1e-32 111.1 11.9 8.2e-06 26.0 0.0 12.2 11 1 1 12 12 12 6 Ankyrin repeat NACHT PF05729.12 KEY68912.1 - 3.9e-05 23.6 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEY68912.1 - 0.076 13.3 0.0 0.33 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 KEY68912.1 - 0.086 12.9 3.6 0.3 11.2 3.6 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation adh_short_C2 PF13561.6 KEY68913.1 - 5.3e-42 144.0 0.0 1.3e-40 139.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY68913.1 - 9e-39 132.9 0.0 1.6e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY68913.1 - 6.3e-11 42.5 0.3 5.1e-10 39.5 0.0 2.1 1 1 0 2 2 2 1 KR domain DUF1776 PF08643.10 KEY68913.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glu_dehyd_C PF16912.5 KEY68913.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Epimerase PF01370.21 KEY68913.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KEY68913.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KEY68913.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3543 PF12063.8 KEY68914.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Protoglobin PF11563.8 KEY68915.1 - 1.1e-56 191.2 0.1 1.3e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 Protoglobin SNF PF00209.18 KEY68917.1 - 4.9e-79 266.4 37.6 5.5e-78 262.9 37.6 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Sugar_tr PF00083.24 KEY68918.1 - 3.9e-96 322.6 24.3 5e-96 322.3 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY68918.1 - 3.6e-19 68.9 22.7 3.6e-19 68.9 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KEY68919.1 - 2.5e-18 66.1 2.0 4.8e-18 65.2 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY68919.1 - 1.9e-08 34.3 0.0 8.6e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like ADH_zinc_N PF00107.26 KEY68920.1 - 2.3e-17 63.2 0.1 3.6e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KEY68920.1 - 3.1e-14 52.8 0.0 5.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KEY68920.1 - 1.3e-05 26.2 0.0 4.5e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY68921.1 - 2.9e-36 124.8 0.9 3.7e-36 124.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68921.1 - 1.9e-27 96.3 0.1 2.6e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY68921.1 - 0.0031 17.0 0.5 0.0068 15.9 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KEY68922.1 - 2.6e-69 233.6 0.0 7.1e-69 232.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEY68922.1 - 4.8e-55 186.9 0.0 7.8e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY68922.1 - 1.8e-52 178.9 0.8 3e-52 178.1 0.8 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY68922.1 - 4.2e-39 133.2 0.1 1.1e-38 131.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY68922.1 - 3.9e-22 78.8 0.5 5.3e-21 75.2 0.1 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 KEY68922.1 - 1.5e-17 64.1 0.2 4.6e-17 62.5 0.1 2.0 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KEY68922.1 - 1.2e-14 54.4 0.0 5.3e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68922.1 - 1.3e-13 52.2 0.0 5.7e-13 50.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY68922.1 - 7.8e-06 25.7 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KEY68922.1 - 0.00055 19.5 0.0 0.0017 17.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase HhH-GPD PF00730.25 KEY68923.1 - 1.1e-14 54.7 0.0 2.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.14 KEY68924.1 - 1.2e-108 362.6 0.0 1.4e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KEY68924.1 - 0.0018 18.1 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Snf7 PF03357.21 KEY68925.1 - 3.6e-26 91.8 18.9 3.6e-26 91.8 18.9 2.2 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 KEY68925.1 - 0.29 9.7 7.1 0.46 9.0 6.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 KEY68925.1 - 0.43 10.0 6.4 0.18 11.3 3.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4407 PF14362.6 KEY68925.1 - 1.6 8.0 14.8 0.14 11.5 9.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CFEM PF05730.11 KEY68926.1 - 0.021 14.9 4.2 0.043 13.9 4.2 1.5 1 0 0 1 1 1 0 CFEM domain Podoplanin PF05808.11 KEY68926.1 - 0.16 12.1 3.5 0.43 10.7 3.5 1.7 1 0 0 1 1 1 0 Podoplanin DUF4483 PF14825.6 KEY68927.1 - 0.049 13.4 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Phage_holin_3_6 PF07332.11 KEY68927.1 - 0.34 10.9 16.6 0.2 11.7 3.4 3.9 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 KEY68929.1 - 5.6e-51 173.4 0.0 7.6e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY68929.1 - 2.5e-18 66.3 0.0 4.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY68929.1 - 0.062 13.2 0.7 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY68929.1 - 0.22 11.1 0.4 0.43 10.1 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.11 KEY68930.1 - 9.6e-91 304.5 0.6 1.1e-90 304.2 0.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KEY68930.1 - 0.023 14.1 0.2 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.8 KEY68930.1 - 0.1 11.0 3.6 0.18 10.2 0.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3292) polyprenyl_synt PF00348.17 KEY68931.1 - 2.2e-64 217.0 0.0 2.7e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.11 KEY68932.1 - 2.9e-129 430.2 0.3 1.3e-65 221.3 0.1 2.0 1 1 1 2 2 2 2 Cell division control protein 14, SIN component DUF347 PF03988.12 KEY68933.1 - 0.028 14.6 1.7 0.056 13.7 1.7 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Podoplanin PF05808.11 KEY68933.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.9 3 0 0 3 3 3 0 Podoplanin EphA2_TM PF14575.6 KEY68933.1 - 0.14 13.0 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KEY68933.1 - 5.5 6.9 4.4 1.1 9.2 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain IDO PF01231.18 KEY68934.1 - 7.1e-34 117.3 0.0 8.9e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.11 KEY68936.1 - 2.1e-80 270.2 21.2 2.7e-80 269.8 21.2 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 AraC_N PF06719.13 KEY68936.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus CLTH PF10607.9 KEY68937.1 - 6e-32 110.6 0.0 1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KEY68937.1 - 1e-24 87.0 0.1 1.5e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KEY68937.1 - 3e-05 23.8 0.3 0.00025 20.9 0.0 2.5 3 0 0 3 3 3 1 LisH GST_N_4 PF17172.4 KEY68938.1 - 3.7e-18 66.1 0.1 9.1e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEY68938.1 - 1.7e-14 53.3 0.1 3.2e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KEY68938.1 - 8.9e-10 38.9 0.0 1.7e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KEY68938.1 - 0.014 15.4 0.6 0.031 14.3 0.6 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 KEY68938.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 SAM35, subunit of SAM coomplex adh_short PF00106.25 KEY68940.1 - 1.3e-42 145.5 0.0 1.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY68940.1 - 3.3e-40 138.1 0.4 3.8e-40 137.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY68940.1 - 2.2e-09 37.5 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY68940.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPMT PF05724.11 KEY68941.1 - 3.8e-26 92.1 0.0 2e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KEY68941.1 - 7.5e-08 32.4 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY68941.1 - 1.7e-05 24.7 0.0 6.5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY68941.1 - 1.8e-05 25.4 0.0 3.3e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY68941.1 - 2.2e-05 25.0 0.0 5.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY68941.1 - 0.00069 20.3 0.0 0.0021 18.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KEY68941.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB OTU PF02338.19 KEY68942.1 - 3.3e-20 72.9 0.8 1.5e-19 70.7 0.0 2.3 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KEY68942.1 - 0.005 16.3 0.0 0.46 9.9 0.0 2.6 2 0 0 2 2 2 2 Peptidase C65 Otubain Lin-8 PF03353.15 KEY68942.1 - 2.3 7.7 17.5 3.2 7.2 17.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 KEY68942.1 - 2.5 6.7 5.3 2.8 6.5 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mcp5_PH PF12814.7 KEY68943.1 - 5.4e-47 158.9 0.0 1e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KEY68943.1 - 0.00014 22.3 16.2 0.00014 22.3 16.2 1.8 2 0 0 2 2 2 1 Fez1 TPR_MLP1_2 PF07926.12 KEY68943.1 - 0.037 14.1 22.1 0.023 14.7 12.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ras PF00071.22 KEY68945.1 - 1.1e-50 171.4 0.0 2.3e-50 170.4 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY68945.1 - 5.9e-17 62.0 0.0 5.5e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY68945.1 - 0.0021 17.6 0.0 0.0058 16.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEY68945.1 - 0.035 14.0 0.0 9.2 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KEY68945.1 - 0.053 13.0 0.1 0.75 9.3 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_25 PF13481.6 KEY68945.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Opy2 PF09463.10 KEY68946.1 - 2.3e-05 24.6 19.8 3.5e-05 24.0 19.8 1.3 1 0 0 1 1 1 1 Opy2 protein Chitin_synth_1 PF01644.17 KEY68947.1 - 2.1e-68 229.4 0.0 3.1e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEY68947.1 - 1.4e-27 95.4 0.0 2.5e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEY68947.1 - 6.4e-27 94.4 0.1 6e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEY68947.1 - 9.9e-09 35.4 0.1 9.9e-09 35.4 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY68947.1 - 0.0016 18.4 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2417 PF10329.9 KEY68947.1 - 0.14 11.5 3.7 0.16 11.3 0.1 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) UQ_con PF00179.26 KEY68948.1 - 1.8e-36 124.9 0.0 2.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 KEY68949.1 - 2.8e-45 153.8 0.0 4.5e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KEY68949.1 - 4.9e-41 140.4 0.0 8e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KEY68949.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEY68949.1 - 0.12 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.25 KEY68950.1 - 1.2e-56 192.3 5.5 2.4e-56 191.3 5.5 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEY68950.1 - 0.16 11.2 0.2 0.25 10.6 0.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KEY68951.1 - 3.9e-44 151.0 44.8 6.9e-40 137.1 27.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY68951.1 - 2.6e-08 33.2 7.0 2.6e-08 33.2 7.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KEY68951.1 - 0.00027 20.3 10.2 0.00027 20.3 10.2 3.2 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB VPDSG-CTERM PF18205.1 KEY68951.1 - 3.5 7.6 9.7 16 5.4 1.7 3.4 2 0 0 2 2 2 0 VPDSG-CTERM motif Aldedh PF00171.22 KEY68952.1 - 4.2e-18 65.1 14.8 1.2e-10 40.5 10.3 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Tfb5 PF06331.12 KEY68952.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 URO-D PF01208.17 KEY68952.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Fanconi_A_N PF15865.5 KEY68952.1 - 0.065 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Rep_fac-A_C PF08646.10 KEY68953.1 - 1.2e-50 171.1 0.6 1.8e-48 164.0 0.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KEY68953.1 - 5.8e-37 125.5 0.8 1.5e-36 124.3 0.8 1.7 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 KEY68953.1 - 3.3e-17 62.4 0.1 1.2e-16 60.6 0.1 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KEY68953.1 - 7.2e-14 51.5 0.6 8.8e-10 38.4 0.0 3.6 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain POT1 PF02765.17 KEY68953.1 - 0.0031 17.3 0.0 0.012 15.4 0.1 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF4503 PF14951.6 KEY68953.1 - 0.0057 15.2 0.4 0.0094 14.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) CDC24_OB3 PF17244.2 KEY68953.1 - 0.0094 15.7 0.2 0.043 13.5 0.2 2.1 1 1 0 1 1 1 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KEY68953.1 - 0.014 13.3 0.0 0.02 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DLH PF01738.18 KEY68954.1 - 2.1e-17 63.4 0.1 4.2e-16 59.2 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEY68954.1 - 0.00098 18.8 0.0 0.81 9.3 0.1 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 KEY68955.1 - 5e-23 81.5 0.1 9.4e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY68955.1 - 9.7e-23 81.7 0.0 1.5e-22 81.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY68955.1 - 2.5e-09 37.0 0.0 3.6e-08 33.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3724 PF12521.8 KEY68956.1 - 1.1 9.3 4.4 27 5.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) AMP-binding PF00501.28 KEY68957.1 - 1.4e-70 238.1 0.0 1.8e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEY68957.1 - 1.8e-18 66.2 0.5 3.9e-18 65.1 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KEY68957.1 - 5.7e-18 65.7 0.3 2.3e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BRCT_2 PF16589.5 KEY68958.1 - 8.9e-10 38.8 0.0 4.3e-09 36.7 0.0 2.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KEY68958.1 - 4.8e-05 23.2 0.1 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KEY68958.1 - 0.0017 18.7 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KEY68958.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain KilA-N PF04383.13 KEY68959.1 - 0.00042 20.1 0.0 0.008 16.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Fungal_TACC PF12709.7 KEY68960.1 - 3.6e-11 43.3 0.3 3.6e-11 43.3 0.3 4.5 3 1 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 KEY68960.1 - 5e-06 26.9 7.9 5e-06 26.9 7.9 4.5 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) TACC_C PF05010.14 KEY68960.1 - 0.057 13.2 28.6 0.24 11.2 20.2 2.5 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LPP PF04728.13 KEY68960.1 - 0.8 10.1 4.3 15 6.1 0.1 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 KEY68960.1 - 1 9.8 18.9 0.41 11.1 0.5 4.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KEY68960.1 - 1 9.7 7.3 11 6.5 0.5 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF745 PF05335.13 KEY68960.1 - 1.3 8.7 21.0 0.11 12.3 10.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) GAS PF13851.6 KEY68960.1 - 1.8 7.9 37.4 0.43 9.9 8.1 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2570 PF10828.8 KEY68960.1 - 6.2 6.7 13.6 4.4 7.2 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF4407 PF14362.6 KEY68960.1 - 6.2 6.1 26.8 3.8 6.8 8.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KEY68960.1 - 7.4 6.3 26.0 2.8 7.6 9.9 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) Amidohydro_2 PF04909.14 KEY68961.1 - 9.9e-28 97.7 1.4 2.3e-27 96.6 1.4 1.5 1 1 0 1 1 1 1 Amidohydrolase AMPK1_CBM PF16561.5 KEY68962.1 - 0.00034 20.8 0.0 0.0007 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 KEY68962.1 - 0.061 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Starch binding domain Senescence_reg PF04520.13 KEY68962.1 - 0.093 13.6 10.1 0.15 12.9 7.4 2.1 2 0 0 2 2 2 0 Senescence regulator Presenilin PF01080.17 KEY68962.1 - 0.22 10.2 1.6 0.27 10.0 1.6 1.1 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 KEY68962.1 - 0.44 9.8 8.5 0.69 9.2 8.5 1.2 1 0 0 1 1 1 0 FAM76 protein Transformer PF06495.11 KEY68962.1 - 0.5 10.4 14.3 0.93 9.6 14.3 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Zip PF02535.22 KEY68962.1 - 1.2 8.3 3.6 1.4 8.1 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RAP1 PF07218.11 KEY68962.1 - 1.4 7.1 25.3 0.0092 14.3 11.4 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.13 KEY68962.1 - 4.1 8.1 8.4 23 5.6 5.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sdh5 PF03937.16 KEY68963.1 - 1.8e-25 88.7 0.3 6.3e-25 86.9 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase HD PF01966.22 KEY68964.1 - 6.2e-06 26.4 0.2 1.3e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 HD domain RMI1_C PF16099.5 KEY68964.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold MIOX PF05153.15 KEY68964.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol oxygenase 3A PF00803.18 KEY68964.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family PBP_N PF17093.5 KEY68966.1 - 4.5 7.5 12.9 2.8 8.2 9.4 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus HR1 PF02185.16 KEY68967.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Hr1 repeat zf-U1 PF06220.12 KEY68968.1 - 8.1e-22 76.7 3.4 1.3e-21 76.1 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger Actin_micro PF17003.5 KEY68968.1 - 0.19 10.9 0.2 0.21 10.7 0.2 1.0 1 0 0 1 1 1 0 Putative actin-like family EMP24_GP25L PF01105.24 KEY68969.1 - 8e-40 136.7 0.0 1e-39 136.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Helicase_RecD PF05127.14 KEY68969.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Helicase EzrA PF06160.12 KEY68969.1 - 0.22 9.6 0.7 0.28 9.3 0.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MIS13 PF08202.11 KEY68970.1 - 4.7e-57 193.6 0.8 7.9e-57 192.8 0.8 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Aft1_HRR PF11787.8 KEY68971.1 - 1.9e-30 105.9 3.5 1.9e-30 105.9 3.5 2.9 3 0 0 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 KEY68971.1 - 1e-25 89.9 9.1 1e-25 89.9 9.1 3.4 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 KEY68971.1 - 4.6e-23 81.4 17.0 2.1e-22 79.3 9.6 3.4 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KEY68971.1 - 1.9e-12 47.1 6.6 2.8e-12 46.5 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY68971.1 - 9.3e-06 25.6 7.1 1.5e-05 25.0 7.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY68971.1 - 0.0025 18.3 3.1 0.0047 17.4 3.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.9 KEY68971.1 - 0.1 11.2 3.2 0.12 10.9 3.2 1.1 1 0 0 1 1 1 0 Macoilin family ZapB PF06005.12 KEY68971.1 - 0.11 13.0 0.8 0.19 12.2 0.7 1.4 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KEY68971.1 - 0.4 10.5 1.4 0.7 9.7 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator GST_N_3 PF13417.6 KEY68972.1 - 3.5e-06 27.3 0.1 7.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY68972.1 - 1.8e-05 24.9 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY68972.1 - 0.00031 20.7 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEY68972.1 - 0.0074 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ACTH_assoc PF16102.5 KEY68973.1 - 0.099 13.4 0.0 0.36 11.7 0.0 2.0 1 0 0 1 1 1 0 ACTH-associated domain zf-CCHC PF00098.23 KEY68974.1 - 3.6e-56 184.9 85.7 1.8e-07 30.9 3.4 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 KEY68974.1 - 4e-14 52.1 73.0 0.0014 18.4 3.7 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 KEY68974.1 - 2.5e-10 39.9 54.2 0.36 10.6 0.3 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_3 PF13917.6 KEY68974.1 - 7.7e-06 25.8 71.3 0.032 14.2 1.4 9.9 3 3 7 10 10 10 6 Zinc knuckle zf-C2H2_10 PF16588.5 KEY68974.1 - 0.00038 20.1 4.7 0.00071 19.2 1.7 9.8 10 0 0 10 10 10 5 C2H2 zinc-finger zf-CCHC_6 PF15288.6 KEY68974.1 - 0.032 14.1 72.8 0.28 11.0 0.5 10.1 7 2 2 10 10 10 0 Zinc knuckle Peptidase_S10 PF00450.22 KEY68975.1 - 5.2e-115 385.2 0.0 6.7e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4381 PF14316.6 KEY68975.1 - 0.18 12.1 0.1 0.33 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNA_Me_trans PF04252.13 KEY68976.1 - 3.6e-83 278.1 0.0 4e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Acetyltransf_1 PF00583.25 KEY68978.1 - 1.3e-07 31.9 0.0 2.5e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY68978.1 - 2.3e-07 31.1 0.2 2e-06 28.1 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY68978.1 - 2e-06 27.8 0.0 8.1e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY68978.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY68978.1 - 0.0082 16.1 0.0 0.022 14.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KEY68978.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 KEY68979.1 - 1.9e-09 37.0 0.0 3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPX PF03105.19 KEY68981.1 - 2.3e-06 27.8 17.9 0.00023 21.2 0.1 3.6 2 1 2 4 4 4 3 SPX domain HSBP1 PF06825.12 KEY68981.1 - 0.055 13.3 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF3147 PF11345.8 KEY68981.1 - 0.095 13.1 2.0 0.17 12.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Bcl-2 PF00452.19 KEY68981.1 - 0.23 12.2 1.2 0.57 10.9 0.3 2.0 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family DUF2721 PF11026.8 KEY68981.1 - 1.6 8.6 11.8 0.047 13.6 3.2 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF2721) DEAD PF00270.29 KEY68982.1 - 2.1e-49 167.7 0.0 6.3e-48 162.9 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY68982.1 - 2.9e-25 88.8 0.1 1.6e-24 86.4 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY68982.1 - 6.1e-05 23.1 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KEY68982.1 - 0.011 16.1 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 KEY68982.1 - 0.048 13.5 0.2 0.088 12.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2443 PF10398.9 KEY68982.1 - 0.075 13.1 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Pyr_redox_2 PF07992.14 KEY68983.1 - 2.5e-53 181.2 0.2 3.2e-53 180.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY68983.1 - 9.7e-13 48.5 0.0 4.6e-11 43.1 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY68983.1 - 0.00036 19.9 1.1 0.11 11.7 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEY68983.1 - 0.0079 16.6 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding TetR_C_19 PF17924.1 KEY68983.1 - 0.075 13.6 0.1 0.44 11.2 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rubrerythrin PF02915.17 KEY68983.1 - 0.19 12.1 0.8 0.54 10.7 0.1 2.1 2 0 0 2 2 2 0 Rubrerythrin XhlA PF10779.9 KEY68983.1 - 4.8 7.5 7.2 9.9 6.5 1.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF1180 PF06679.12 KEY68984.1 - 0.0041 17.5 2.5 0.0041 17.5 2.5 3.3 1 1 1 3 3 3 1 Protein of unknown function (DUF1180) ATP-synt_I PF03899.15 KEY68984.1 - 0.17 12.3 0.4 0.29 11.5 0.4 1.2 1 0 0 1 1 1 0 ATP synthase I chain Phos_pyr_kin PF08543.12 KEY68985.1 - 7.3e-77 258.1 0.1 9.6e-77 257.7 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KEY68985.1 - 3.2e-37 128.4 0.1 4.1e-20 72.5 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 KEY68985.1 - 6.4e-08 32.3 0.1 6.3e-07 29.0 0.1 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 KEY68985.1 - 0.044 13.2 1.8 0.28 10.5 1.2 2.4 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.6 KEY68986.1 - 3.1e-134 447.6 0.1 6.8e-134 446.5 0.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KEY68986.1 - 4.8e-39 132.3 0.0 6.8e-36 122.2 0.0 4.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KEY68986.1 - 1.4e-37 128.4 0.1 1.2e-35 122.1 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KEY68986.1 - 1.7e-30 105.0 0.3 9e-29 99.5 0.1 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KEY68986.1 - 6.5e-17 61.4 11.3 1.7e-16 60.1 11.3 1.8 1 0 0 1 1 1 1 Hr1 repeat DUF724 PF05266.14 KEY68986.1 - 0.0034 17.2 3.7 0.0065 16.3 3.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Uds1 PF15456.6 KEY68986.1 - 0.087 13.0 8.5 0.29 11.3 8.5 1.9 1 0 0 1 1 1 0 Up-regulated During Septation DLP_helical PF18709.1 KEY68986.1 - 0.3 10.2 5.0 0.57 9.3 5.0 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain Allexi_40kDa PF05549.11 KEY68986.1 - 0.66 9.4 2.5 1.4 8.4 2.5 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Osteoregulin PF07175.11 KEY68986.1 - 2.2 8.5 5.8 2.3 8.4 4.3 1.8 2 0 0 2 2 2 0 Osteoregulin Uricase PF01014.18 KEY68987.1 - 2.1e-79 264.2 1.6 2.3e-42 144.3 0.4 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 KEY68988.1 - 1.3e-42 145.0 0.1 2.5e-42 144.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 HMA PF00403.26 KEY68989.1 - 4.1e-13 49.5 0.1 7e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KEY68989.1 - 6.6e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chordopox_RPO7 PF05864.12 KEY68989.1 - 0.24 11.7 0.4 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TPR_1 PF00515.28 KEY68990.1 - 3.2e-15 55.2 2.7 8.3e-08 31.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY68990.1 - 1.5e-13 49.7 5.5 5e-06 26.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY68990.1 - 6e-11 42.5 0.8 7.4e-07 29.4 0.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY68990.1 - 8.8e-10 38.0 0.2 1.5e-05 24.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEY68990.1 - 3.7e-08 33.5 0.1 0.027 15.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY68990.1 - 6.1e-07 29.0 0.6 4.4e-05 23.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEY68990.1 - 2.2e-06 27.2 3.3 2.5e-05 23.9 0.5 3.5 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 KEY68990.1 - 8.4e-06 25.6 0.4 1.7e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.6 KEY68990.1 - 0.00056 20.5 5.6 0.003 18.2 0.7 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY68990.1 - 0.00058 20.1 0.3 0.64 10.5 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY68990.1 - 0.00063 19.8 0.1 0.56 10.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY68990.1 - 0.019 14.8 1.1 0.21 11.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY68990.1 - 0.025 15.4 1.6 0.13 13.2 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KEY68990.1 - 0.067 13.3 0.1 0.25 11.4 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KEY68990.1 - 0.094 13.4 0.4 36 5.4 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 KEY68991.1 - 6.1e-86 288.1 0.0 8.1e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KEY68992.1 - 5.2e-37 127.2 0.1 7.9e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEY68992.1 - 1.9e-24 85.5 4.6 3.2e-24 84.8 4.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEY68992.1 - 4.1e-14 52.7 18.6 7.1e-14 51.9 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEY68992.1 - 0.00017 21.5 10.2 0.021 14.8 1.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEY68992.1 - 0.022 14.7 7.8 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KEY68992.1 - 0.042 13.1 2.7 0.53 9.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Malate_DH PF12434.8 KEY68992.1 - 0.084 12.9 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Malate dehydrogenase enzyme zf-RING_10 PF16685.5 KEY68992.1 - 2.5 8.3 13.4 3.1 8.0 2.4 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 KEY68992.1 - 6.8 6.3 10.2 5.3 6.7 1.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 EAP30 PF04157.16 KEY68993.1 - 1.7e-72 243.6 0.0 1.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Mpv17_PMP22 PF04117.12 KEY68994.1 - 2.9e-07 30.6 3.9 1.7e-06 28.1 3.0 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family PDH PF02153.17 KEY68996.1 - 1.7e-14 53.5 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KEY68996.1 - 5.8e-07 30.0 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEY68996.1 - 4.3e-06 27.0 0.0 6.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KEY68996.1 - 7.2e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEY68996.1 - 0.00072 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KEY68996.1 - 0.0096 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KEY68996.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EccE PF11203.8 KEY68996.1 - 0.032 14.6 0.4 4.4 7.7 0.3 3.0 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Shikimate_DH PF01488.20 KEY68996.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ScsC_N PF18312.1 KEY68996.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain RCC1 PF00415.18 KEY68997.1 - 1e-30 106.1 13.7 1.7e-10 41.3 0.1 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEY68997.1 - 2.7e-21 74.8 30.8 2.8e-06 27.0 1.4 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 KEY68998.1 - 6.3e-47 160.1 0.0 7.5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Glyco_hydro_18 PF00704.28 KEY69000.1 - 9.5e-61 206.2 0.0 1.1e-60 206.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KEY69000.1 - 0.0035 17.2 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) FAR1 PF03101.15 KEY69001.1 - 1.8e-06 28.5 0.3 3e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 KEY69001.1 - 0.0031 17.9 0.5 0.0059 17.0 0.4 1.4 1 1 0 1 1 1 1 Transcription factor AFT Sugarporin_N PF11471.8 KEY69001.1 - 0.0034 17.3 0.1 0.0076 16.2 0.1 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension XhlA PF10779.9 KEY69001.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.6 1 1 0 1 1 1 1 Haemolysin XhlA DUF1664 PF07889.12 KEY69001.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC154 PF15450.6 KEY69001.1 - 0.072 11.6 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 DUF3552 PF12072.8 KEY69001.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSBP1 PF06825.12 KEY69001.1 - 0.36 10.7 4.4 4.1 7.3 1.2 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Ribosomal_L34e PF01199.18 KEY69003.1 - 1.4e-42 143.9 2.1 2e-42 143.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DZR PF12773.7 KEY69003.1 - 0.032 14.2 0.3 0.051 13.6 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon FhuF_C PF11575.8 KEY69003.1 - 0.98 9.4 6.1 1.7 8.7 0.3 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.14 KEY69004.1 - 5.1e-29 100.5 0.0 8.6e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_1 PF00561.20 KEY69005.1 - 2.1e-16 60.3 0.1 6.2e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY69005.1 - 1.4e-15 57.3 0.0 5.6e-14 52.0 0.0 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY69005.1 - 7e-13 49.7 6.4 7e-13 49.7 6.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DSPc PF00782.20 KEY69005.1 - 1.3e-09 37.9 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KEY69005.1 - 2.3e-06 27.9 0.1 7.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PTPlike_phytase PF14566.6 KEY69005.1 - 0.00019 21.6 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Abhydrolase_4 PF08386.10 KEY69005.1 - 0.00062 19.8 0.2 0.0046 17.0 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein Y_phosphatase PF00102.27 KEY69005.1 - 0.0038 16.8 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.13 KEY69005.1 - 0.005 16.6 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 KEY69005.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Alk_phosphatase PF00245.20 KEY69006.1 - 8.2e-106 354.4 0.0 1e-105 354.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KEY69006.1 - 5.1e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KEY69006.1 - 0.026 14.1 0.2 0.098 12.2 0.2 2.0 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase C5HCH PF17982.1 KEY69008.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 NSD Cys-His rich domain CorA PF01544.18 KEY69009.1 - 8.3e-30 104.1 11.9 1.3e-24 87.1 7.8 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein ACR_tran PF00873.19 KEY69009.1 - 0.0097 13.6 0.0 0.013 13.2 0.0 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DNA_ligase_A_M PF01068.21 KEY69011.1 - 2.2e-45 154.8 0.0 4.9e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEY69011.1 - 9e-43 146.6 0.0 2.1e-42 145.4 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KEY69011.1 - 3.1e-18 66.6 0.0 7.7e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 KEY69011.1 - 5.9e-14 52.5 0.3 2.8e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KEY69011.1 - 1.8e-12 47.5 0.0 5e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_IV PF11411.8 KEY69011.1 - 5.5e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.26 KEY69011.1 - 0.00069 19.9 0.0 0.0044 17.4 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 KEY69011.1 - 0.0092 15.8 1.2 3.1 7.6 0.0 3.1 3 0 0 3 3 3 2 mRNA capping enzyme, catalytic domain Phage_min_cap2 PF06152.11 KEY69011.1 - 0.17 10.7 0.0 0.42 9.4 0.0 1.5 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF4315 PF14193.6 KEY69011.1 - 0.64 10.1 4.2 0.38 10.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) UPRTase PF14681.6 KEY69012.1 - 1.3e-72 243.6 0.0 1.4e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEY69012.1 - 8.7e-06 25.3 0.2 2e-05 24.2 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 KEY69012.1 - 0.055 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TMP-TENI PF02581.17 KEY69012.1 - 0.089 12.1 0.9 0.66 9.3 0.2 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 KEY69013.1 - 4e-35 120.0 25.5 6e-22 77.8 8.7 2.6 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4470 PF14737.6 KEY69014.1 - 2.4e-09 37.3 0.0 5.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEY69014.1 - 2.7e-07 30.5 11.8 5.4e-07 29.6 11.8 1.4 1 0 0 1 1 1 1 MYND finger Amidohydro_3 PF07969.11 KEY69015.1 - 4.8e-14 52.7 0.2 2.4e-10 40.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KEY69015.1 - 8.8e-11 41.7 0.0 3.1e-09 36.6 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family CFEM PF05730.11 KEY69017.1 - 1e-09 38.3 9.5 1e-09 38.3 9.5 1.6 2 0 0 2 2 2 1 CFEM domain SLR1-BP PF07333.12 KEY69017.1 - 8.2 7.0 8.5 1.6 9.2 2.3 2.4 1 1 1 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) GST_C_3 PF14497.6 KEY69018.1 - 8.7e-28 96.4 0.0 1.6e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY69018.1 - 9.6e-05 22.3 0.0 0.0002 21.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY69018.1 - 0.0094 16.1 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain JAB PF01398.21 KEY69019.1 - 9.8e-32 109.4 0.1 1.5e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KEY69019.1 - 3.9e-21 75.7 2.4 7.2e-21 74.9 2.4 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KEY69019.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4360 PF14273.6 KEY69020.1 - 6.6e-22 78.2 0.8 8.3e-22 77.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4449 PF14613.6 KEY69021.1 - 1.2e-67 227.1 1.8 1.2e-67 227.1 1.8 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) P4Ha_N PF08336.11 KEY69021.1 - 0.048 13.7 3.9 2.6 8.1 0.1 2.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3818 PF12825.7 KEY69022.1 - 4.6e-48 164.0 0.0 1.2e-32 113.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KEY69022.1 - 3e-39 134.0 0.0 6.7e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 PX-associated PAP1 PF08601.10 KEY69022.1 - 0.083 12.6 1.9 0.16 11.7 1.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Sigma70_r4_2 PF08281.12 KEY69022.1 - 0.53 10.0 2.4 11 5.8 0.0 3.5 4 0 0 4 4 4 0 Sigma-70, region 4 Ribosomal_S19e PF01090.19 KEY69024.1 - 1.4e-57 193.3 0.2 1.6e-57 193.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Zip PF02535.22 KEY69025.1 - 1.1e-66 225.3 0.8 1.3e-66 225.1 0.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MDM10 PF12519.8 KEY69026.1 - 4.7e-158 526.9 0.1 1.9e-133 445.7 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KEY69026.1 - 0.005 16.3 0.0 1.5 8.2 0.1 2.5 2 0 0 2 2 2 2 Eukaryotic porin LSM PF01423.22 KEY69027.1 - 1.9e-15 56.3 0.2 2.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KEY69027.1 - 0.0039 16.8 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein Baculo_gp41 PF04700.12 KEY69027.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region LDB19 PF13002.7 KEY69029.1 - 5.3e-34 117.6 0.5 8e-34 117.0 0.5 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KEY69029.1 - 8.2e-07 29.2 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_S4Pg PF11993.8 KEY69029.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) HET PF06985.11 KEY69030.1 - 0.043 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 KEY69031.1 - 7.6e-63 212.2 0.1 9.4e-63 211.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 KEY69031.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) CorA PF01544.18 KEY69032.1 - 0.00019 20.9 7.8 0.00046 19.6 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF4381 PF14316.6 KEY69032.1 - 1.3 9.3 6.7 3 8.1 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TFIIA PF03153.13 KEY69035.1 - 1.3 8.9 9.3 2.6 8.0 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fmp27 PF10344.9 KEY69036.1 - 7.8e-203 676.1 0.0 1.3e-202 675.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KEY69036.1 - 9.6e-192 638.1 2.1 9.6e-192 638.1 2.1 2.8 3 1 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KEY69036.1 - 3.1e-180 600.1 0.3 3.1e-180 600.1 0.3 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KEY69036.1 - 7.8e-55 185.3 0.0 1.6e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KEY69036.1 - 9.5e-53 178.3 0.4 2.1e-52 177.1 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KEY69036.1 - 2.1e-30 105.5 0.0 8.4e-30 103.5 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.13 KEY69036.1 - 0.019 14.9 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Tim17 PF02466.19 KEY69037.1 - 0.023 15.1 0.5 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family PT-VENN PF04829.13 KEY69037.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 KEY69038.1 - 1.8e-11 43.7 0.0 3.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KEY69038.1 - 3.7 7.6 15.3 5.8 6.9 15.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NUDIX PF00293.28 KEY69039.1 - 9.3e-14 51.6 0.1 2.5e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain ABA_GPCR PF12430.8 KEY69040.1 - 1.9e-54 184.2 1.0 2.8e-54 183.6 0.1 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KEY69040.1 - 2.1e-26 91.8 0.2 2.4e-25 88.4 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Usp PF00582.26 KEY69041.1 - 2.3e-16 60.6 0.2 1.2e-15 58.2 0.0 2.2 2 1 0 2 2 2 1 Universal stress protein family KcnmB2_inactiv PF09303.10 KEY69042.1 - 0.35 10.7 1.7 1.4 8.8 1.7 2.0 1 0 0 1 1 1 0 KCNMB2, ball and chain domain FAM199X PF15814.5 KEY69042.1 - 0.71 8.9 7.7 0.8 8.7 7.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X Paf67 PF10255.9 KEY69043.1 - 2.4e-156 520.8 0.4 2.9e-156 520.6 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KEY69043.1 - 0.042 14.0 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat End_beta_barrel PF12195.8 KEY69043.1 - 0.044 13.7 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase GTP_EFTU PF00009.27 KEY69044.1 - 9.9e-58 194.9 0.0 1.5e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEY69044.1 - 5.7e-17 61.5 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY69044.1 - 4.9e-09 36.5 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEY69044.1 - 9.5e-09 35.2 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KEY69044.1 - 0.0013 18.5 0.0 0.022 14.5 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KEY69044.1 - 0.025 14.6 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pyr_redox_3 PF13738.6 KEY69045.1 - 5.6e-11 42.3 0.0 7.8e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY69045.1 - 4.5e-08 32.6 0.0 7.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KEY69045.1 - 7.4e-07 28.0 0.0 1.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEY69045.1 - 5.4e-05 22.6 0.0 0.00021 20.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOT1 PF08123.13 KEY69047.1 - 9e-72 240.9 0.0 1.7e-71 240.0 0.1 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KEY69047.1 - 0.0021 18.7 0.1 0.005 17.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY69047.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY69047.1 - 0.096 13.4 0.0 0.3 11.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69047.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.11 KEY69048.1 - 4.1e-52 177.3 18.9 4.7e-52 177.1 18.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.21 KEY69048.1 - 1.6e-05 24.7 5.5 1.6e-05 24.7 5.5 2.0 1 1 1 2 2 2 1 Intermediate filament protein FPP PF05911.11 KEY69048.1 - 0.00014 20.2 10.9 0.00017 19.9 10.9 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KEY69048.1 - 0.001 18.6 10.4 0.0012 18.4 10.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 SurA_N PF09312.11 KEY69048.1 - 0.0026 17.8 4.5 0.0026 17.8 4.5 1.9 2 1 1 3 3 2 1 SurA N-terminal domain APG6_N PF17675.1 KEY69048.1 - 0.011 16.3 16.7 0.47 11.0 16.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 KEY69048.1 - 0.023 13.8 11.5 0.03 13.4 11.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 KEY69048.1 - 0.029 14.5 7.0 0.029 14.5 7.0 2.1 2 1 1 3 3 2 0 Nucleoporin complex subunit 54 FAM76 PF16046.5 KEY69048.1 - 0.034 13.5 10.0 0.043 13.2 10.0 1.2 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 KEY69048.1 - 0.044 13.4 6.3 0.051 13.1 6.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 KEY69048.1 - 0.052 13.9 5.7 0.071 13.4 2.8 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 KEY69048.1 - 0.053 13.8 13.8 0.036 14.3 11.8 1.7 2 0 0 2 2 1 0 Flagellar FliJ protein TMF_TATA_bd PF12325.8 KEY69048.1 - 0.069 13.4 16.8 1.5 9.1 4.6 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KEY69048.1 - 0.1 11.5 16.4 0.32 9.8 16.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.6 KEY69048.1 - 0.1 12.3 14.8 0.11 12.2 12.5 2.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.9 KEY69048.1 - 0.11 12.8 8.6 0.17 12.2 8.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Macoilin PF09726.9 KEY69048.1 - 0.14 10.7 11.3 0.17 10.4 11.3 1.1 1 0 0 1 1 1 0 Macoilin family Cob_adeno_trans PF01923.18 KEY69048.1 - 0.19 11.9 6.9 0.078 13.1 3.2 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase KELK PF15796.5 KEY69048.1 - 0.24 11.9 18.5 0.78 10.2 0.9 3.6 2 1 1 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 KEY69048.1 - 0.29 10.4 16.5 0.37 10.1 14.5 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KEY69048.1 - 0.39 10.0 12.4 0.62 9.4 12.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KEY69048.1 - 0.39 8.6 4.8 0.44 8.4 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family USP8_interact PF08941.10 KEY69048.1 - 0.82 9.5 6.8 0.63 9.8 5.2 1.6 2 0 0 2 2 1 0 USP8 interacting SlyX PF04102.12 KEY69048.1 - 1.1 9.9 10.3 15 6.3 2.2 3.4 2 1 1 3 3 3 0 SlyX FlxA PF14282.6 KEY69048.1 - 1.4 9.0 8.3 0.66 10.0 5.4 1.9 2 0 0 2 2 2 0 FlxA-like protein LMBR1 PF04791.16 KEY69048.1 - 1.5 7.6 3.2 1.6 7.6 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tho2 PF11262.8 KEY69048.1 - 2.6 7.2 6.5 4.3 6.4 6.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1664 PF07889.12 KEY69048.1 - 2.6 8.1 7.6 2.9 7.9 6.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KEY69048.1 - 2.8 7.6 14.6 15 5.3 14.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF745) FlaC_arch PF05377.11 KEY69048.1 - 3.4 8.1 10.2 19 5.8 3.2 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KEY69048.1 - 4 7.5 13.7 13 5.8 13.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KEY69048.1 - 4.2 7.9 9.1 15 6.1 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 KEY69048.1 - 5.1 7.7 11.3 9.6 6.8 9.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 KEY69048.1 - 5.2 6.2 5.8 7.3 5.7 5.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tnp_22_trimer PF17489.2 KEY69048.1 - 5.8 7.0 16.4 3.5 7.7 0.4 3.8 2 1 2 4 4 4 0 L1 transposable element trimerization domain Fmp27_WPPW PF10359.9 KEY69048.1 - 6.3 5.5 11.8 1.9 7.2 9.2 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain BRE1 PF08647.11 KEY69048.1 - 9.6 6.4 17.0 4.3 7.5 10.6 2.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Vps16_N PF04841.13 KEY69049.1 - 8.8e-86 288.2 0.0 1.2e-85 287.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KEY69049.1 - 1.1e-82 277.7 0.0 1.5e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KEY69049.1 - 0.039 14.3 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 KEY69050.1 - 5.2e-15 55.6 0.0 9.6e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KEY69050.1 - 3.4e-13 49.1 6.2 6.1e-13 48.3 6.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KEY69050.1 - 5.1e-07 29.9 8.1 9.6e-07 29.0 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KEY69050.1 - 0.00096 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KEY69050.1 - 0.017 14.9 7.8 0.03 14.2 7.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY69050.1 - 0.03 14.3 5.5 0.052 13.5 5.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KEY69050.1 - 0.037 13.9 3.8 0.073 13.0 3.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KEY69050.1 - 0.11 12.5 7.8 0.25 11.4 7.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY69050.1 - 0.16 11.9 8.7 0.3 11.0 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEY69050.1 - 1.1 9.6 7.9 3.3 8.1 7.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KEY69050.1 - 2.3 8.4 6.0 5.2 7.3 6.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.21 KEY69051.1 - 7.7e-53 179.2 0.0 2.3e-52 177.6 0.0 1.8 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEY69051.1 - 6.9e-43 146.2 0.0 8.6e-41 139.4 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) S1 PF00575.23 KEY69053.1 - 4.4e-78 257.6 44.2 3.8e-14 52.8 0.3 13.4 13 0 0 13 13 13 12 S1 RNA binding domain S1_2 PF13509.6 KEY69053.1 - 1.9e-05 24.6 0.1 5.4 7.2 0.0 5.3 5 0 0 5 5 5 2 S1 domain Suf PF05843.14 KEY69053.1 - 0.00083 19.4 7.0 0.15 12.0 0.0 3.6 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KEY69053.1 - 0.00084 19.2 16.6 0.082 12.9 0.1 7.8 10 0 0 10 10 10 2 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 KEY69053.1 - 0.0026 18.5 6.3 9.7 7.3 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY69053.1 - 0.037 14.6 0.5 8.6 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2187 PF09953.9 KEY69053.1 - 0.058 13.4 0.2 0.92 9.6 0.1 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) Fungal_trans PF04082.18 KEY69054.1 - 3.1e-16 59.2 0.1 4.8e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69054.1 - 7.7e-12 45.1 24.4 1e-08 35.1 11.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP-1 PF03085.15 KEY69054.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MAP65_ASE1 PF03999.12 KEY69055.1 - 3.8e-75 253.8 11.7 4.5e-75 253.5 10.9 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 KEY69055.1 - 4.6 5.1 6.5 7.2 4.4 0.1 2.7 2 1 1 3 3 3 0 Prominin BLOC1_2 PF10046.9 KEY69055.1 - 7 7.0 7.1 6.4 7.2 2.8 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_4 PF12763.7 KEY69056.1 - 1.9e-06 27.8 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KEY69056.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KEY69056.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Amidase PF01425.21 KEY69057.1 - 1.9e-71 241.4 0.0 1e-70 239.0 0.0 1.8 1 1 0 1 1 1 1 Amidase peroxidase PF00141.23 KEY69058.1 - 5.1e-27 95.1 0.0 7.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF2278 PF10042.9 KEY69060.1 - 2.9e-69 233.2 0.1 4.2e-69 232.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 KEY69060.1 - 4.8e-05 23.7 0.0 0.00017 21.9 0.0 1.9 1 0 0 1 1 1 1 Lamin Tail Domain Hemerythrin PF01814.23 KEY69062.1 - 3.2e-12 47.2 4.5 4.8e-12 46.6 4.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BfiI_DBD PF18243.1 KEY69062.1 - 0.047 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain Ank_4 PF13637.6 KEY69063.1 - 8.9e-09 35.7 0.2 0.085 13.5 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69063.1 - 7.2e-07 29.0 0.1 6.5 7.7 0.0 6.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 KEY69063.1 - 8.5e-07 29.5 0.0 0.056 14.0 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEY69063.1 - 0.068 13.6 3.7 26 5.5 0.1 4.9 6 0 0 6 6 6 0 Ankyrin repeat eIF-3c_N PF05470.12 KEY69064.1 - 1.2e-175 585.3 24.7 4.2e-143 477.8 0.6 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KEY69064.1 - 4.2e-13 49.7 0.0 1.6e-12 47.9 0.0 2.1 1 0 0 1 1 1 1 PCI domain DUF2779 PF11074.8 KEY69064.1 - 0.21 12.1 1.4 3.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function(DUF2779) Fe-S_biosyn PF01521.20 KEY69065.1 - 4.1e-11 43.1 0.0 1.8e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 KEY69066.1 - 7.6e-25 87.0 16.2 1.4e-24 86.1 16.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KEY69066.1 - 3.1e-19 68.6 2.6 3.1e-19 68.6 2.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.19 KEY69067.1 - 2.2e-46 156.8 1.6 2.8e-46 156.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 KEY69067.1 - 0.073 12.8 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CBM_25 PF03423.13 KEY69067.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SNF2_N PF00176.23 KEY69068.1 - 5.4e-66 222.7 0.1 2.5e-65 220.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY69068.1 - 3.9e-16 59.4 0.0 9.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY69068.1 - 7.6e-08 32.5 0.0 3.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4164 PF13747.6 KEY69068.1 - 0.45 10.8 8.8 0.71 10.2 5.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.6 KEY69068.1 - 3.4 8.1 8.0 0.47 10.8 2.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ApbA_C PF08546.11 KEY69069.1 - 3.3e-28 98.4 0.0 5.6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KEY69069.1 - 1.1e-20 73.8 0.0 4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA RBM39linker PF15519.6 KEY69069.1 - 0.054 14.6 0.0 0.14 13.3 0.0 1.6 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Myb_DNA-bind_6 PF13921.6 KEY69070.1 - 3.9e-15 55.9 0.3 3.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEY69070.1 - 6.4e-14 51.9 0.2 7.2e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.6 KEY69070.1 - 0.03 14.0 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) AtuA PF07287.11 KEY69070.1 - 0.075 11.7 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Sigma70_r4_2 PF08281.12 KEY69070.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Metallophos PF00149.28 KEY69071.1 - 5.7e-10 40.0 0.0 7.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 KEY69072.1 - 1.9e-15 56.9 0.0 6.2e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69072.1 - 5.4e-05 22.6 0.0 0.00047 19.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY69073.1 - 4.2e-24 85.3 0.0 1.3e-23 83.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain HET PF06985.11 KEY69073.1 - 5.7e-22 78.6 0.0 1.3e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 KEY69073.1 - 7.5e-15 54.9 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.18 KEY69074.1 - 5.3e-05 23.3 3.5 5.3e-05 23.3 3.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KEY69075.1 - 6.5e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY69075.1 - 4.5e-14 52.5 0.0 7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY69075.1 - 4.7e-10 39.6 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY69075.1 - 6.2e-09 36.0 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY69075.1 - 2.2e-06 27.6 0.2 4.3e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY69075.1 - 7.2e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 KEY69076.1 - 8.6e-23 81.1 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY69076.1 - 9.8e-21 74.5 0.0 1.7e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEY69076.1 - 7e-08 32.8 0.1 1.9e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEY69076.1 - 0.00089 18.8 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KEY69076.1 - 0.0056 17.1 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KEY69076.1 - 0.029 14.5 0.0 0.085 13.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KEY69076.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY69076.1 - 0.047 12.8 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 KEY69076.1 - 0.12 11.5 0.0 0.8 8.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 KEY69077.1 - 5.6e-05 22.3 0.3 0.00022 20.3 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.12 KEY69079.1 - 0.083 13.4 1.3 0.22 12.0 1.3 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KEY69079.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.2 2 0 0 2 2 2 0 EB module Ig_GlcNase PF18368.1 KEY69079.1 - 6.2 7.0 10.9 15 5.8 1.0 2.3 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain AA_permease PF00324.21 KEY69080.1 - 3e-65 220.7 27.5 7.9e-65 219.3 27.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY69080.1 - 1.9e-27 96.1 26.4 2.7e-27 95.7 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.12 KEY69080.1 - 1.1e-20 73.5 1.3 1.9e-20 72.8 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY69080.1 - 2.7e-19 69.4 0.0 5.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY69080.1 - 0.00041 21.4 0.0 0.00084 20.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY69080.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M36 PF02128.15 KEY69081.1 - 2e-136 455.1 1.5 2.4e-136 454.8 1.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KEY69081.1 - 4.1e-17 61.7 1.1 1.2e-16 60.3 1.1 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PLDc PF00614.22 KEY69081.1 - 0.057 13.6 0.0 0.21 11.8 0.0 2.1 1 0 0 1 1 1 0 Phospholipase D Active site motif Acyl_transf_1 PF00698.21 KEY69082.1 - 1.2e-12 48.0 0.1 7.1e-12 45.5 0.1 1.8 1 1 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KEY69082.1 - 0.091 12.5 0.4 3 7.5 0.2 2.1 1 1 1 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Tannase PF07519.11 KEY69083.1 - 2.2e-20 73.0 0.0 2.3e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tryp_inh PF17983.1 KEY69084.1 - 0.12 12.5 0.4 0.29 11.3 0.4 1.6 1 0 0 1 1 1 0 Trypsin inhibitors 1,2 and 3 Phlebovirus_G2 PF07245.11 KEY69084.1 - 0.19 10.2 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Zn_clus PF00172.18 KEY69085.1 - 2.4e-11 43.5 12.0 6e-11 42.3 12.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY69085.1 - 8.9e-06 24.9 0.1 0.0003 19.9 0.0 2.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain BLOC1_2 PF10046.9 KEY69085.1 - 0.067 13.5 0.3 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADH_zinc_N_2 PF13602.6 KEY69086.1 - 1.2e-10 42.6 0.0 8.8e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY69086.1 - 1.7e-08 34.5 0.2 3.2e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY69086.1 - 0.0071 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 KEY69086.1 - 0.028 14.2 0.4 7.9 6.3 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF521 PF04412.13 KEY69086.1 - 0.17 10.5 0.1 0.31 9.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) zf-C2H2 PF00096.26 KEY69087.1 - 3.9e-21 74.2 31.4 2.1e-06 27.8 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY69087.1 - 8.2e-16 57.6 39.5 1.7e-06 28.2 0.2 5.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY69087.1 - 3.3e-07 30.6 35.8 0.013 16.3 1.2 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY69087.1 - 0.00019 21.6 2.5 0.54 10.6 0.3 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KEY69087.1 - 0.0013 18.9 8.9 0.22 11.8 5.6 3.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 KEY69087.1 - 0.014 16.1 2.4 0.014 16.1 2.4 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KEY69087.1 - 0.015 15.1 2.0 0.015 15.1 2.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KEY69087.1 - 0.03 14.7 0.7 0.03 14.7 0.7 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KEY69087.1 - 6.6 6.8 10.9 5.7 7.0 0.1 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KEY69087.1 - 7.9 7.2 19.0 5 7.8 0.3 5.1 3 1 2 5 5 5 0 FOXP coiled-coil domain Peptidase_M41 PF01434.18 KEY69088.1 - 5.3e-55 186.2 2.5 1.3e-54 185.0 2.0 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KEY69088.1 - 4.9e-44 150.0 0.0 1.2e-43 148.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY69088.1 - 8.5e-07 29.1 0.1 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY69088.1 - 1.1e-05 25.7 0.3 0.056 13.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEY69088.1 - 1.4e-05 25.5 0.1 8.4e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KEY69088.1 - 0.0001 21.7 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 KEY69088.1 - 0.00011 22.0 0.9 0.00029 20.6 0.9 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEY69088.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEY69088.1 - 0.0031 17.7 0.0 0.014 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEY69088.1 - 0.0091 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KEY69088.1 - 0.01 15.4 0.1 0.085 12.4 0.0 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 KEY69088.1 - 0.012 15.5 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_25 PF13481.6 KEY69088.1 - 0.012 15.2 0.4 1.4 8.5 0.2 2.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEY69088.1 - 0.023 14.1 1.1 0.044 13.2 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cloacin PF03515.14 KEY69088.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain AAA_14 PF13173.6 KEY69088.1 - 0.061 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KEY69088.1 - 0.066 13.3 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KEY69088.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KEY69088.1 - 0.09 12.0 3.0 0.76 9.0 0.4 2.9 2 1 1 3 3 3 0 Zeta toxin AAA_28 PF13521.6 KEY69088.1 - 0.092 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEY69088.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY69088.1 - 0.11 13.1 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEY69088.1 - 0.17 11.8 0.2 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain RVT_1 PF00078.27 KEY69088.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PhoH PF02562.16 KEY69088.1 - 0.24 10.8 1.0 0.43 10.0 0.3 1.7 2 0 0 2 2 2 0 PhoH-like protein Epimerase PF01370.21 KEY69089.1 - 1e-19 71.0 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY69089.1 - 2.8e-15 56.1 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY69089.1 - 4.1e-11 42.9 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEY69089.1 - 5.1e-11 42.2 0.0 1.9e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KEY69089.1 - 5e-09 36.3 0.1 7.2e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEY69089.1 - 1e-07 31.4 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KEY69089.1 - 4.2e-06 26.4 0.2 7.1e-06 25.6 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69089.1 - 2e-05 24.6 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KEY69089.1 - 4.5e-05 23.1 0.1 8.7e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KEY69089.1 - 0.0003 21.3 0.0 0.00067 20.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KEY69089.1 - 0.0024 17.0 0.1 0.0049 16.0 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short_C2 PF13561.6 KEY69089.1 - 0.062 12.8 0.8 0.16 11.5 0.8 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF4448 PF14610.6 KEY69090.1 - 0.00042 20.1 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF4690 PF15756.5 KEY69090.1 - 0.029 15.0 0.1 0.029 15.0 0.1 2.2 3 0 0 3 3 3 0 Small Novel Rich in Cartilage SKG6 PF08693.10 KEY69090.1 - 0.27 10.7 4.5 0.57 9.6 4.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short_C2 PF13561.6 KEY69092.1 - 1.2e-56 191.9 0.3 1.4e-56 191.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69092.1 - 8.4e-47 159.2 0.1 1e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69092.1 - 8.6e-11 42.1 0.2 2.4e-10 40.6 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69092.1 - 0.00082 18.9 0.0 0.0013 18.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ORC6 PF05460.13 KEY69093.1 - 1.7e-30 106.5 12.3 4.7e-30 105.1 5.5 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) adh_short PF00106.25 KEY69094.1 - 4.3e-23 81.8 0.0 3.7e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69094.1 - 3e-08 33.5 0.0 2.6e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69094.1 - 8.2e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain EF-hand_1 PF00036.32 KEY69095.1 - 0.00072 18.9 0.2 0.0013 18.1 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEY69095.1 - 0.0012 18.6 0.1 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KEY69095.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 EF hand Met_10 PF02475.16 KEY69096.1 - 5.8e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Metallophos PF00149.28 KEY69097.1 - 5.8e-33 115.1 0.0 2.5e-28 100.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KEY69097.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KEY69097.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Smg4_UPF3 PF03467.15 KEY69098.1 - 4.4e-48 163.6 0.0 4.4e-48 163.6 0.0 3.0 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KEY69098.1 - 2.3e-07 30.5 0.0 4e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANTAR PF03861.14 KEY69098.1 - 0.022 14.6 0.6 0.24 11.3 0.7 2.3 2 0 0 2 2 2 0 ANTAR domain Putative_PNPOx PF01243.20 KEY69099.1 - 0.0008 19.6 0.0 0.0022 18.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATG16 PF08614.11 KEY69100.1 - 0.00064 20.0 17.6 0.00064 20.0 17.6 2.2 1 1 0 2 2 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 KEY69100.1 - 0.0015 18.9 22.8 0.0053 17.2 7.7 3.7 2 1 2 4 4 4 2 Cell division protein ZapB Mod_r PF07200.13 KEY69100.1 - 0.0023 18.1 13.0 0.0023 18.1 13.0 1.9 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 KEY69100.1 - 0.0049 16.9 5.3 0.0087 16.1 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) COG6 PF06419.11 KEY69100.1 - 0.0067 14.7 7.9 0.0067 14.7 7.9 1.7 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 Mt_ATP-synt_D PF05873.12 KEY69100.1 - 0.0098 15.8 2.6 0.0098 15.8 2.6 2.3 1 1 1 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) RasGAP_C PF03836.15 KEY69100.1 - 0.023 14.9 9.8 0.25 11.5 1.6 2.4 1 1 1 2 2 2 0 RasGAP C-terminus DivIC PF04977.15 KEY69100.1 - 0.026 14.3 24.8 0.048 13.4 5.1 3.9 2 1 2 4 4 4 0 Septum formation initiator Laminin_II PF06009.12 KEY69100.1 - 0.091 12.8 11.1 0.11 12.5 8.3 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF5636 PF18686.1 KEY69100.1 - 0.29 11.3 8.9 0.21 11.8 6.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5636) XhlA PF10779.9 KEY69100.1 - 0.47 10.7 17.7 0.27 11.4 8.0 3.3 1 1 2 3 3 3 0 Haemolysin XhlA Sec34 PF04136.15 KEY69100.1 - 0.5 10.2 11.4 0.93 9.4 1.5 2.2 1 1 1 2 2 2 0 Sec34-like family DUF3450 PF11932.8 KEY69100.1 - 0.53 9.6 20.6 0.69 9.2 7.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2353 PF09789.9 KEY69100.1 - 0.62 9.4 28.7 2.2 7.6 27.8 2.0 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KxDL PF10241.9 KEY69100.1 - 0.7 10.2 12.9 3.5 8.0 5.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein TSC22 PF01166.18 KEY69100.1 - 1.4 9.3 9.5 2.8 8.3 1.0 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Prominin PF05478.11 KEY69100.1 - 2.2 6.1 5.7 3 5.7 5.7 1.1 1 0 0 1 1 1 0 Prominin DUF3810 PF12725.7 KEY69100.1 - 3.3 7.0 7.1 7.2 5.9 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DLEU7 PF15760.5 KEY69100.1 - 4.5 6.7 8.2 12 5.3 4.0 2.2 2 0 0 2 2 2 0 Leukemia-associated protein 7 Cor1 PF04803.12 KEY69100.1 - 5.1 7.3 19.2 3.3 7.9 13.6 2.8 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region HALZ PF02183.18 KEY69100.1 - 5.2 7.4 14.2 2.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1366 PF07104.11 KEY69100.1 - 5.3 6.8 9.1 1.6 8.4 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) DUF4201 PF13870.6 KEY69100.1 - 7.4 6.3 29.4 0.025 14.3 14.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Fzo_mitofusin PF04799.13 KEY69100.1 - 7.7 6.0 7.1 11 5.5 6.7 1.4 1 1 0 1 1 1 0 fzo-like conserved region Gly_transf_sug PF04488.15 KEY69102.1 - 1.9e-15 57.3 0.2 3.4e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KEY69102.1 - 9e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KEY69102.1 - 0.0048 16.3 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Rax2 PF12768.7 KEY69103.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 KEY69103.1 - 0.0027 17.1 1.9 0.007 15.7 1.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KEY69103.1 - 0.011 16.6 0.1 0.027 15.3 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 KEY69103.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Phage_holin_2_1 PF04971.12 KEY69103.1 - 0.061 13.3 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S Gram_pos_anchor PF00746.21 KEY69103.1 - 0.092 12.7 1.6 0.18 11.8 1.6 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_holin_2_4 PF16082.5 KEY69103.1 - 0.097 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TMEM154 PF15102.6 KEY69103.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF4690 PF15756.5 KEY69103.1 - 0.2 12.3 2.4 20 5.8 1.2 2.5 1 1 1 2 2 2 0 Small Novel Rich in Cartilage RAP1 PF07218.11 KEY69103.1 - 4.3 5.5 4.7 4.7 5.4 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.12 KEY69103.1 - 4.9 5.4 5.2 6.3 5.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RTA1 PF04479.13 KEY69105.1 - 5.6e-65 218.8 14.4 7.8e-65 218.3 14.4 1.2 1 0 0 1 1 1 1 RTA1 like protein OAD_gamma PF04277.13 KEY69105.1 - 0.096 13.3 0.3 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF996 PF06195.13 KEY69105.1 - 9.8 6.5 14.2 0.39 11.0 1.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF996) ketoacyl-synt PF00109.26 KEY69108.1 - 3.8e-61 206.9 0.0 8.8e-61 205.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEY69108.1 - 8.3e-55 186.1 0.0 1.3e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KEY69108.1 - 6e-54 182.7 0.5 5.2e-53 179.6 0.0 2.7 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KEY69108.1 - 3.1e-49 168.2 0.0 5.4e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY69108.1 - 1.1e-36 125.5 0.1 4.5e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY69108.1 - 2.3e-15 57.0 0.0 8.2e-15 55.2 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KEY69108.1 - 2.2e-14 54.7 0.1 7.8e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY69108.1 - 4.9e-14 52.4 0.0 1.4e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY69108.1 - 2.9e-10 39.9 0.4 8.3e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KEY69108.1 - 4.2e-07 29.8 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY69108.1 - 0.00018 21.8 0.1 0.0011 19.3 0.0 2.4 2 0 0 2 2 1 1 Phosphopantetheine attachment site HTH_51 PF18558.1 KEY69108.1 - 0.032 14.1 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Thiolase_N PF00108.23 KEY69108.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain AlaDh_PNT_C PF01262.21 KEY69108.1 - 0.062 12.6 0.2 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_4 PF01565.23 KEY69109.1 - 4.5e-24 84.8 1.1 8.4e-24 83.9 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69109.1 - 2.2e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KEY69110.1 - 1.4e-46 159.3 0.0 2.1e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY69111.1 - 5.6e-59 200.1 0.0 7.6e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KEY69113.1 - 8.4e-07 28.6 0.0 2.9e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 Cupin domain adh_short PF00106.25 KEY69114.1 - 5.9e-25 87.9 0.0 7e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69114.1 - 7.2e-19 68.3 0.0 8.8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69114.1 - 0.0032 17.4 0.1 0.005 16.8 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69114.1 - 0.0048 16.4 0.0 0.0072 15.8 0.0 1.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY69114.1 - 0.051 13.5 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 KEY69115.1 - 1.4e-56 191.6 1.4 2.7e-56 190.7 1.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69115.1 - 1.4e-38 132.3 0.6 2.2e-38 131.7 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69115.1 - 6.1e-07 29.5 0.3 3e-06 27.3 0.3 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KEY69116.1 - 1.6e-16 60.3 0.0 2.8e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY69116.1 - 3.4e-09 36.8 0.0 5.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY69116.1 - 5.2e-06 26.2 0.0 8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4818 PF16089.5 KEY69116.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) Putative_PNPOx PF01243.20 KEY69118.1 - 1.4e-08 34.8 0.0 0.0014 18.8 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KEY69118.1 - 0.02 15.2 0.0 0.85 10.0 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEY69118.1 - 0.087 13.5 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain KCH PF16944.5 KEY69119.1 - 2.7e-99 332.0 8.0 3.3e-99 331.7 8.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel Pkinase PF00069.25 KEY69120.1 - 0.051 12.9 0.0 21 4.4 0.0 2.9 3 0 0 3 3 3 0 Protein kinase domain Glyoxalase PF00903.25 KEY69123.1 - 6e-40 136.4 0.4 1.3e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEY69123.1 - 7.3e-16 58.4 0.1 4.6e-06 26.9 0.0 3.7 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KEY69123.1 - 2.4e-06 27.5 1.8 0.0038 17.1 0.2 4.0 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KEY69123.1 - 3e-05 24.2 0.0 0.31 11.1 0.0 3.2 1 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KEY69123.1 - 0.0001 23.1 0.0 0.83 10.5 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain MoaF PF10703.9 KEY69123.1 - 0.0075 16.2 0.0 0.55 10.2 0.0 2.5 2 0 0 2 2 2 1 MoaF N-terminal domain DUF1338 PF07063.13 KEY69123.1 - 0.066 12.4 0.1 48 3.0 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF1338) CppA_N PF14506.6 KEY69123.1 - 0.081 13.0 0.1 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 CppA N-terminal NIL PF09383.10 KEY69123.1 - 0.16 11.8 0.0 5.8 6.8 0.0 2.3 2 0 0 2 2 2 0 NIL domain DUF21 PF01595.20 KEY69124.1 - 3.5e-34 118.0 0.0 5.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEY69124.1 - 2.1e-06 28.1 1.7 0.023 15.2 0.1 3.2 2 0 0 2 2 2 2 CBS domain Lactonase PF10282.9 KEY69125.1 - 2e-13 50.3 0.0 4.9e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 KEY69126.1 - 2.9e-44 150.7 0.0 4.6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEY69126.1 - 3.7e-26 90.8 0.2 6.3e-26 90.0 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEY69126.1 - 0.0042 17.3 0.0 0.019 15.2 0.0 2.1 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KEY69126.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain Drf_GBD PF06371.13 KEY69127.1 - 4.6e-13 49.2 3.3 1.2e-11 44.5 3.3 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain RraA-like PF03737.15 KEY69128.1 - 3.7e-27 95.4 0.0 5.8e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA Vps36_ESCRT-II PF11605.8 KEY69129.1 - 0.028 14.6 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KEY69129.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 1 0 1 1 1 0 Bacterial PH domain UCR_hinge PF02320.16 KEY69130.1 - 5.9e-27 93.7 11.4 5.9e-27 93.7 11.4 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Tim54 PF11711.8 KEY69130.1 - 0.086 11.6 12.0 0.094 11.5 12.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RPN2_C PF18004.1 KEY69130.1 - 0.16 11.9 13.2 0.2 11.6 13.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4471 PF14740.6 KEY69130.1 - 0.18 11.0 4.9 0.25 10.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Nop14 PF04147.12 KEY69130.1 - 0.21 9.7 20.9 0.23 9.6 20.9 1.0 1 0 0 1 1 1 0 Nop14-like family GET2 PF08690.10 KEY69130.1 - 0.21 11.2 9.5 0.28 10.8 9.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Myc_N PF01056.18 KEY69130.1 - 0.23 11.3 16.9 0.31 10.9 16.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NPR3 PF03666.13 KEY69130.1 - 0.46 9.2 8.1 0.5 9.1 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KEY69130.1 - 0.48 10.6 3.0 0.58 10.3 3.0 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 KEY69130.1 - 0.72 8.6 9.4 0.72 8.6 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KEY69130.1 - 1.2 7.4 13.9 1.3 7.2 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KEY69130.1 - 1.3 8.1 15.2 1.5 7.9 15.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 KEY69130.1 - 1.7 7.5 6.4 1.9 7.4 6.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 KEY69130.1 - 1.8 8.3 17.0 2.4 7.9 17.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF853 PF05872.12 KEY69130.1 - 2.3 6.7 6.7 2.7 6.5 6.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF913 PF06025.12 KEY69130.1 - 2.9 6.8 8.8 3.2 6.6 8.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 KEY69130.1 - 4 6.1 12.3 4.6 5.9 12.3 1.1 1 0 0 1 1 1 0 Raftlin PPL5 PF18168.1 KEY69130.1 - 4.1 6.6 9.4 4.9 6.4 9.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Adeno_terminal PF02459.15 KEY69130.1 - 5.3 5.3 10.2 6.2 5.1 10.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF4045 PF13254.6 KEY69130.1 - 5.4 6.5 15.1 6.2 6.4 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 KEY69130.1 - 9.2 5.6 24.6 11 5.4 24.6 1.1 1 0 0 1 1 1 0 SDA1 MFS_1 PF07690.16 KEY69131.1 - 4.1e-23 81.9 39.3 4.1e-23 81.9 39.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KEY69131.1 - 8.6e-06 24.6 2.8 8.6e-06 24.6 2.8 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein DUF3810 PF12725.7 KEY69131.1 - 0.17 11.2 1.2 0.31 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MFS_1_like PF12832.7 KEY69131.1 - 0.32 9.8 8.7 0.036 12.9 1.9 2.3 1 1 1 2 2 2 0 MFS_1 like family adh_short PF00106.25 KEY69132.1 - 0.0056 16.2 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KH_1 PF00013.29 KEY69133.1 - 1.8e-100 328.8 25.7 2.7e-13 49.5 0.1 14.2 14 1 0 14 14 14 9 KH domain SLS PF14611.6 KEY69133.1 - 1.2e-13 51.4 1.2 0.17 11.7 0.0 7.4 3 1 5 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KEY69133.1 - 1.6e-11 43.9 29.8 0.025 14.4 0.1 8.2 8 1 0 9 9 9 5 KH domain KH_4 PF13083.6 KEY69133.1 - 0.00042 20.1 13.1 0.32 10.9 0.1 6.2 8 0 0 8 8 8 2 KH domain DUF5300 PF17224.3 KEY69133.1 - 0.037 14.3 5.4 10 6.4 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) BON PF04972.17 KEY69133.1 - 0.43 10.9 4.6 16 5.9 0.0 4.7 4 0 0 4 4 4 0 BON domain DUF2067 PF09840.9 KEY69133.1 - 2.1 7.9 6.6 7 6.2 0.1 4.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2067) Pkinase PF00069.25 KEY69134.1 - 6.7e-73 245.3 0.0 9.6e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69134.1 - 8.1e-47 159.7 0.0 1.3e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KEY69134.1 - 1.7e-19 69.9 0.0 4.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KEY69134.1 - 3e-08 33.3 0.0 5.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEY69134.1 - 4.8e-07 28.9 0.1 1.3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KEY69134.1 - 0.0064 15.5 0.3 0.014 14.4 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY69134.1 - 0.013 14.8 0.1 0.085 12.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY69134.1 - 0.076 12.9 0.0 0.076 12.9 0.0 2.3 2 2 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KEY69134.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 KEY69135.1 - 6.4e-63 212.4 1.3 8.1e-63 212.1 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69135.1 - 3.1e-51 173.6 1.0 4.3e-51 173.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69135.1 - 2e-11 44.1 0.2 2.9e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69135.1 - 3.9e-06 26.5 0.1 3.2e-05 23.5 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PA PF02225.22 KEY69135.1 - 0.0022 18.0 0.2 0.017 15.2 0.1 2.3 2 0 0 2 2 2 1 PA domain GDP_Man_Dehyd PF16363.5 KEY69135.1 - 0.004 16.6 0.1 0.0078 15.6 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY69135.1 - 0.0091 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4202 PF13875.6 KEY69135.1 - 0.12 12.2 0.0 0.88 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) Mustang PF15682.5 KEY69135.1 - 0.17 12.0 0.0 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 ARID PF01388.21 KEY69136.1 - 5.7e-18 65.4 0.1 2.3e-17 63.4 0.1 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain TFIIA PF03153.13 KEY69136.1 - 0.00068 19.7 4.1 0.00068 19.7 4.1 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit NAAA-beta PF15508.6 KEY69136.1 - 0.1 12.9 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SelP_N PF04592.14 KEY69136.1 - 8.3 5.7 15.2 16 4.8 15.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ysc84 PF04366.12 KEY69138.1 - 2.6e-41 140.4 0.4 3.9e-41 139.8 0.4 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KEY69138.1 - 3.7e-15 55.2 0.3 1.4e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KEY69138.1 - 2.1e-14 52.9 0.1 4.8e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KEY69138.1 - 1.4e-11 44.1 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ArfGap PF01412.18 KEY69140.1 - 4.2e-40 136.5 0.6 6.1e-40 136.0 0.6 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KEY69140.1 - 0.03 14.1 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain SelR PF01641.18 KEY69141.1 - 8.7e-50 167.8 0.1 1.2e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 KEY69141.1 - 0.0051 16.8 0.4 0.6 10.2 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_10 PF10058.9 KEY69141.1 - 0.012 15.3 0.4 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KEY69141.1 - 0.026 14.7 0.4 0.07 13.4 0.4 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Thiolase_N PF00108.23 KEY69142.1 - 1.5e-72 244.1 3.5 2.2e-72 243.5 3.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY69142.1 - 2.4e-41 140.3 0.1 5.2e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KEY69142.1 - 0.0053 16.9 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KEY69142.1 - 0.031 13.9 1.3 0.11 12.0 0.4 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Cadherin_tail PF15974.5 KEY69142.1 - 0.13 12.6 0.4 0.32 11.3 0.1 1.8 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region OCD_Mu_crystall PF02423.15 KEY69143.1 - 2.7e-09 36.4 0.2 3.9e-05 22.8 0.0 2.5 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family DUF4147 PF13660.6 KEY69143.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Shikimate_DH PF01488.20 KEY69143.1 - 0.099 12.7 0.1 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Cg6151-P PF10233.9 KEY69144.1 - 4.8e-40 136.4 14.2 5.7e-40 136.1 14.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KEY69144.1 - 0.011 15.5 7.7 0.015 15.0 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 PRA1 PF03208.19 KEY69144.1 - 0.33 10.6 14.5 0.041 13.5 1.7 2.1 1 1 1 2 2 2 0 PRA1 family protein Cytochrom_B558a PF05038.13 KEY69144.1 - 2.9 7.4 7.6 5.5 6.5 6.7 2.0 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Aim21 PF11489.8 KEY69145.1 - 4e-186 621.1 71.9 4e-186 621.1 71.9 2.4 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Dna2 PF08696.11 KEY69147.1 - 9.7e-71 237.8 2.2 1.2e-70 237.4 0.7 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KEY69147.1 - 4.1e-52 176.7 0.2 9.5e-52 175.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 KEY69147.1 - 2.5e-34 119.2 0.3 9.9e-17 61.6 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KEY69147.1 - 1.1e-16 61.2 0.0 5e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEY69147.1 - 8.7e-13 48.8 0.0 3.6e-12 46.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KEY69147.1 - 7.2e-12 45.7 0.7 5.3e-10 39.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KEY69147.1 - 1.5e-07 31.4 0.2 0.27 11.0 0.0 3.7 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KEY69147.1 - 0.00015 21.7 0.0 0.00059 19.7 0.0 2.0 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KEY69147.1 - 0.00031 20.0 0.4 0.051 12.7 0.0 2.5 3 0 0 3 3 3 1 PIF1-like helicase SRP54 PF00448.22 KEY69147.1 - 0.00089 18.9 1.1 0.0024 17.6 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KEY69147.1 - 0.00095 19.6 0.0 0.0053 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 KEY69147.1 - 0.0017 18.4 0.2 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MobB PF03205.14 KEY69147.1 - 0.01 15.7 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.21 KEY69147.1 - 0.014 14.9 1.5 0.021 14.4 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KEY69147.1 - 0.015 14.8 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KEY69147.1 - 0.016 14.8 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KEY69147.1 - 0.017 14.4 0.0 0.041 13.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KEY69147.1 - 0.018 15.1 1.1 0.044 13.8 0.6 1.8 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KEY69147.1 - 0.047 13.9 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEY69147.1 - 0.049 13.2 0.2 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 KEY69147.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KEY69147.1 - 0.086 12.7 0.8 0.2 11.5 0.2 1.9 2 0 0 2 2 1 0 NTPase AAA_5 PF07728.14 KEY69147.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KEY69147.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KEY69147.1 - 0.49 10.4 2.8 0.5 10.4 0.2 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain ESSS PF10183.9 KEY69148.1 - 2.2e-10 40.7 0.0 2.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.19 KEY69149.1 - 5.6e-35 121.2 0.0 7.2e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV UPA PF17217.3 KEY69149.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 UPA domain Pkinase PF00069.25 KEY69150.1 - 7.5e-17 61.6 0.0 3.3e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69150.1 - 1.1e-09 38.0 0.0 1.6e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KEY69150.1 - 0.0013 18.4 0.7 0.0039 16.9 0.1 2.0 1 1 1 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 CAP_N PF01213.19 KEY69151.1 - 0.88 9.0 7.3 1.1 8.7 7.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KEY69151.1 - 1.2 9.1 3.0 1.4 8.9 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator SIR2 PF02146.17 KEY69152.1 - 5.7e-58 195.7 0.0 1e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KEY69152.1 - 0.001 18.8 0.2 0.3 10.8 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KEY69152.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) IFT43 PF15305.6 KEY69152.1 - 0.19 11.9 0.3 0.19 11.9 0.3 2.0 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Cation_ATPase_C PF00689.21 KEY69153.1 - 6.8e-42 143.2 6.9 6.8e-42 143.2 6.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEY69153.1 - 2e-31 108.9 0.4 2e-31 108.9 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEY69153.1 - 4.6e-22 79.4 0.2 9.4e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY69153.1 - 2.9e-21 75.4 0.0 6.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY69153.1 - 3.7e-06 26.9 0.8 9.1e-06 25.6 0.8 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY69153.1 - 1.4e-05 24.7 0.1 4.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KEY69153.1 - 0.005 17.3 0.0 0.0086 16.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KEY69153.1 - 0.16 11.9 0.0 0.68 9.9 0.0 2.0 2 0 0 2 2 2 0 Ferlin C-terminus DUF2976 PF11190.8 KEY69153.1 - 1.3 8.8 7.8 0.73 9.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) TTL PF03133.15 KEY69154.1 - 3.3e-56 190.6 0.0 5.3e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KEY69154.1 - 4.8e-52 176.6 0.0 6.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KEY69154.1 - 3.3e-05 23.3 0.0 8.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 YheC/D like ATP-grasp DASH_Duo1 PF08651.10 KEY69156.1 - 2.3e-32 110.6 0.4 3.2e-32 110.1 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 RIB43A PF05914.12 KEY69156.1 - 0.0024 16.7 5.8 0.0032 16.3 5.8 1.1 1 0 0 1 1 1 1 RIB43A Cgr1 PF03879.14 KEY69156.1 - 0.045 14.1 8.0 0.083 13.3 8.0 1.4 1 0 0 1 1 1 0 Cgr1 family API5 PF05918.11 KEY69156.1 - 0.074 11.9 2.7 0.089 11.6 2.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DinB PF05163.12 KEY69156.1 - 0.13 12.1 2.0 0.22 11.5 2.0 1.4 1 0 0 1 1 1 0 DinB family DUF1682 PF07946.14 KEY69156.1 - 0.18 11.0 3.1 0.24 10.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF737 PF05300.11 KEY69156.1 - 7 7.0 15.4 12 6.2 15.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) RNase_H2-Ydr279 PF09468.10 KEY69157.1 - 3e-44 151.0 1.2 1.6e-43 148.6 0.0 2.3 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KEY69157.1 - 7.7e-23 80.6 0.0 2e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain zf-primase PF09329.11 KEY69158.1 - 2.2e-18 65.8 1.5 3.9e-18 65.0 1.5 1.4 1 0 0 1 1 1 1 Primase zinc finger Tyrosinase PF00264.20 KEY69159.1 - 5.5e-47 160.9 0.9 5.5e-47 160.9 0.9 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KEY69159.1 - 0.059 14.0 0.1 0.44 11.2 0.1 2.2 1 1 0 1 1 1 0 Tyosinase C-terminal domain Acetyltransf_10 PF13673.7 KEY69160.1 - 3.2e-11 43.3 0.0 4.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY69160.1 - 9.2e-08 32.3 0.0 1.5e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY69160.1 - 3.7e-07 30.5 0.0 5.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY69160.1 - 2e-05 24.7 0.1 3.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY69160.1 - 2.9e-05 24.0 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEY69160.1 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Fungal_trans PF04082.18 KEY69161.1 - 3.4e-20 72.2 0.0 6.6e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69161.1 - 0.0063 16.6 8.3 0.011 15.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spermine_synth PF01564.17 KEY69162.1 - 3.1e-07 30.0 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KEY69162.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KEY69162.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KEY69162.1 - 0.15 12.8 0.2 0.4 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Pyridox_ox_2 PF12900.7 KEY69163.1 - 1.5e-39 135.2 0.0 1.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NRBF2 PF08961.10 KEY69164.1 - 0.21 11.2 3.8 1.2 8.7 0.0 3.4 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator ABC_tran PF00005.27 KEY69166.1 - 2.2e-46 157.8 0.4 1.9e-21 77.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KEY69166.1 - 7.4e-21 74.0 7.8 7.4e-21 74.0 7.8 3.9 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 KEY69166.1 - 7.6e-18 65.3 1.6 8.1e-05 22.6 0.0 4.9 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY69166.1 - 8.2e-11 41.8 3.9 0.0014 18.1 0.0 4.8 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KEY69166.1 - 1.7e-07 31.8 0.0 0.014 15.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KEY69166.1 - 3e-07 30.5 0.1 0.0054 16.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY69166.1 - 2.9e-06 27.3 1.3 0.04 13.8 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 KEY69166.1 - 4.8e-06 27.2 15.2 0.023 15.2 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KEY69166.1 - 5.3e-06 26.3 0.0 0.0044 16.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KEY69166.1 - 5.9e-06 25.9 0.2 0.052 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY69166.1 - 1.2e-05 25.8 1.7 0.026 14.9 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY69166.1 - 2.2e-05 24.8 0.0 0.24 11.7 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KEY69166.1 - 2.5e-05 24.4 0.1 0.28 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEY69166.1 - 6.9e-05 22.7 11.0 0.23 11.1 0.0 4.9 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 KEY69166.1 - 0.00016 22.1 0.0 0.33 11.4 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEY69166.1 - 0.00031 20.5 2.2 1.1 8.9 0.2 3.9 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 KEY69166.1 - 0.00069 19.9 3.0 0.21 11.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 KEY69166.1 - 0.0011 18.0 0.7 0.51 9.3 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 KEY69166.1 - 0.0013 18.8 0.0 2.7 8.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KEY69166.1 - 0.0032 17.4 0.2 4.1 7.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 KEY69166.1 - 0.0041 16.7 3.7 3.8 7.1 0.0 4.1 5 1 1 6 6 5 2 AAA domain RNA_helicase PF00910.22 KEY69166.1 - 0.0048 17.3 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 KEY69166.1 - 0.0077 15.8 1.3 1.3 8.6 0.9 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KEY69166.1 - 0.0087 16.1 7.5 3.2 7.8 0.2 4.5 5 0 0 5 5 5 1 Dynamin family NTPase_1 PF03266.15 KEY69166.1 - 0.0091 15.9 0.2 0.99 9.3 0.2 2.6 2 0 0 2 2 2 1 NTPase MobB PF03205.14 KEY69166.1 - 0.0093 15.9 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 KEY69166.1 - 0.01 15.4 0.0 0.84 9.2 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 KEY69166.1 - 0.012 15.2 0.0 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KEY69166.1 - 0.015 15.5 0.2 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KEY69166.1 - 0.017 14.6 0.1 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KEY69166.1 - 0.018 15.0 0.5 8 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEY69166.1 - 0.047 12.9 0.0 0.36 10.0 0.0 2.5 3 0 0 3 3 2 0 TIP49 P-loop domain NB-ARC PF00931.22 KEY69166.1 - 0.054 12.7 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KEY69166.1 - 0.064 13.3 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KEY69166.1 - 0.07 13.1 1.1 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain SbcCD_C PF13558.6 KEY69166.1 - 0.072 13.3 1.4 8.6 6.7 0.3 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 KEY69166.1 - 0.47 10.9 6.5 15 6.0 0.3 4.0 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 KEY69166.1 - 0.59 9.9 2.8 21 4.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 KEY69166.1 - 1.4 8.6 5.7 1.9 8.1 0.0 3.5 4 0 0 4 4 4 0 Thymidylate kinase Tubulin PF00091.25 KEY69167.1 - 1.6e-68 230.8 0.0 4.4e-68 229.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEY69167.1 - 1.1e-43 148.4 0.0 1.6e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KEY69167.1 - 2.3e-05 24.7 0.0 5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KEY69167.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KEY69167.1 - 0.01 15.1 0.0 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Ribosomal_L6 PF00347.23 KEY69168.1 - 3.9e-20 72.3 0.4 1.7e-08 35.0 0.0 3.0 3 1 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.25 KEY69169.1 - 5.2e-52 177.0 1.9 1.4e-51 175.7 1.9 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Complex1_LYR_2 PF13233.6 KEY69170.1 - 1.2e-19 70.8 0.0 1.5e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like SFTA2 PF15210.6 KEY69170.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Surfactant-associated protein 2 Aha1_N PF09229.11 KEY69172.1 - 7.6e-42 142.8 0.6 1.2e-41 142.2 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KEY69172.1 - 1.5e-18 67.2 0.9 3.8e-18 65.9 0.2 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DHHC PF01529.20 KEY69173.1 - 1.8e-30 105.8 1.7 1.8e-30 105.8 1.7 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF969 PF06149.12 KEY69173.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF969) PRRSV_Env PF02340.15 KEY69174.1 - 0.047 13.1 0.6 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 PRRSV putative envelope protein Rap1_C PF11626.8 KEY69175.1 - 1.5e-23 82.7 0.0 2.9e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KEY69175.1 - 1.3e-16 60.5 1.9 2e-16 59.9 0.1 2.2 2 0 0 2 2 2 1 Rap1 Myb domain ARID PF01388.21 KEY69175.1 - 1.3e-05 25.8 0.0 3.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BRCT_2 PF16589.5 KEY69175.1 - 1.5e-05 25.3 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KEY69175.1 - 0.00012 22.6 0.0 0.00048 20.7 0.0 2.0 1 0 0 1 1 1 1 Rap1, DNA-binding Tht1 PF04163.12 KEY69176.1 - 3.1e-06 26.2 1.0 7.8e-06 24.9 0.9 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein MbeD_MobD PF04899.12 KEY69176.1 - 0.0036 17.4 1.9 0.66 10.1 0.4 3.3 2 1 0 2 2 2 1 MbeD/MobD like DUF1664 PF07889.12 KEY69176.1 - 0.0069 16.4 11.4 0.2 11.7 3.7 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KEY69176.1 - 0.094 12.3 12.9 0.23 11.0 0.1 3.0 2 1 1 3 3 3 0 fzo-like conserved region Spt46 PF17734.1 KEY69176.1 - 0.15 11.8 0.9 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 PMC2NT PF08066.12 KEY69176.1 - 0.16 12.7 4.6 0.57 10.9 2.7 2.8 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Hemerythrin PF01814.23 KEY69176.1 - 0.22 12.1 5.6 0.5 11.0 0.3 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain LIF_OSM PF01291.17 KEY69176.1 - 0.24 11.5 8.5 1 9.5 0.1 3.2 1 1 1 3 3 3 0 LIF / OSM family HIP1_clath_bdg PF16515.5 KEY69176.1 - 0.55 10.9 17.0 1.7 9.3 7.9 3.4 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 G-gamma PF00631.22 KEY69176.1 - 1.7 8.7 6.1 18 5.4 0.0 3.3 3 0 0 3 3 3 0 GGL domain Snapin_Pallidin PF14712.6 KEY69176.1 - 1.8 9.1 11.2 0.33 11.4 4.6 3.0 1 1 2 3 3 3 0 Snapin/Pallidin SseC PF04888.12 KEY69176.1 - 2.6 7.6 17.9 11 5.5 16.7 2.1 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF16 PF01519.16 KEY69176.1 - 8.5 6.9 7.5 24 5.5 3.4 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 HLH PF00010.26 KEY69177.1 - 7e-16 57.9 1.0 9.9e-16 57.4 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 KEY69177.1 - 0.36 11.2 7.4 0.56 10.6 6.1 1.9 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Prenyltrans PF00432.21 KEY69178.1 - 5e-32 109.3 34.2 9.9e-08 31.6 0.2 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEY69178.1 - 0.029 13.5 0.1 2.9 6.9 0.0 2.2 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Peptidase_S8 PF00082.22 KEY69180.1 - 4.6e-31 108.2 15.3 2.5e-30 105.8 15.3 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY69180.1 - 1.6e-07 31.9 0.3 6.9e-07 29.9 0.3 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 TatD_DNase PF01026.21 KEY69181.1 - 2.5e-42 145.0 0.0 3.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase NatB_MDM20 PF09797.9 KEY69183.1 - 1.4e-19 70.3 0.0 1e-18 67.5 0.0 2.3 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4646 PF15496.6 KEY69187.1 - 0.00088 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Pro_dh PF01619.18 KEY69188.1 - 2.2e-58 198.2 0.0 2.7e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Cellulase PF00150.18 KEY69188.1 - 0.11 11.9 0.0 0.9 8.9 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) GHL6 PF14871.6 KEY69188.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 AP_endonuc_2 PF01261.24 KEY69188.1 - 0.14 11.5 0.1 0.48 9.8 0.1 1.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.20 KEY69189.1 - 2.2e-88 296.8 0.0 2.7e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PNP_UDP_1 PF01048.20 KEY69190.1 - 1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Thyroglobulin_1 PF00086.18 KEY69190.1 - 0.068 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Pkinase PF00069.25 KEY69191.1 - 8.1e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.26 KEY69191.1 - 0.048 14.1 0.9 0.24 11.9 0.0 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY69191.1 - 1.6 9.8 9.0 1.8 9.6 0.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY69191.1 - 3.4 8.3 0.0 3.4 8.3 0.0 3.3 4 0 0 4 4 4 0 Zinc-finger double domain adh_short PF00106.25 KEY69192.1 - 3e-15 56.2 0.0 9.2e-09 35.0 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69192.1 - 2.4e-10 40.4 0.0 4.1e-07 29.8 0.0 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69192.1 - 8.6e-06 25.8 0.0 2.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY69192.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KEY69193.1 - 1.1e-22 80.3 0.2 1.8e-22 79.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69193.1 - 6.8e-07 29.3 9.9 1.3e-06 28.4 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 KEY69193.1 - 0.1 12.8 0.5 0.67 10.3 0.2 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain adh_short PF00106.25 KEY69194.1 - 5e-17 62.0 0.0 1.1e-15 57.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69194.1 - 7.5e-09 35.5 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69194.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.5 2 0 0 2 2 2 1 KR domain TIR-like PF10137.9 KEY69194.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Epimerase PF01370.21 KEY69194.1 - 0.047 13.2 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ERCC3_RAD25_C PF16203.5 KEY69196.1 - 4.8e-103 343.7 0.0 8.4e-103 342.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KEY69196.1 - 2.7e-30 105.1 0.0 5.3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY69196.1 - 6.5e-17 62.1 0.0 1.5e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY69196.1 - 3.5e-11 43.4 0.0 7.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEY69196.1 - 1.9e-08 33.5 0.0 2.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain p450 PF00067.22 KEY69197.1 - 6.1e-86 289.0 0.0 7.1e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SCIFF PF13165.6 KEY69198.1 - 2.2 8.3 7.5 5.7 7.0 2.0 2.1 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF DUF89 PF01937.19 KEY69200.1 - 2.2e-120 401.9 0.0 2.5e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pkinase PF00069.25 KEY69201.1 - 1.4e-15 57.4 0.0 2.6e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69201.1 - 1.2e-06 28.1 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4337 PF14235.6 KEY69204.1 - 0.56 10.3 4.8 7.5 6.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Aminotran_1_2 PF00155.21 KEY69205.1 - 2.7e-37 128.8 0.0 3.1e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY69205.1 - 6.1e-06 25.0 0.0 8.9e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KEY69205.1 - 8.3e-05 21.5 0.5 0.0012 17.7 0.5 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain PS-DH PF14765.6 KEY69206.1 - 5.4e-66 222.8 1.1 9.1e-66 222.1 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEY69206.1 - 1.6e-61 208.1 0.0 4.6e-61 206.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY69206.1 - 3.3e-60 204.3 0.0 6.1e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY69206.1 - 4.2e-59 199.5 0.0 1.9e-58 197.3 0.0 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEY69206.1 - 8.6e-30 103.2 0.5 7.1e-29 100.2 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY69206.1 - 4.5e-25 88.3 0.0 1.2e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KEY69206.1 - 5.7e-15 55.5 0.0 3.6e-14 52.9 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY69206.1 - 4.4e-12 47.2 0.0 7.4e-11 43.2 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KEY69206.1 - 4.9e-10 39.4 0.0 1.7e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69206.1 - 8.4e-10 38.7 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY69206.1 - 1.2e-09 38.8 0.0 3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69206.1 - 3.2e-07 30.9 0.0 1.4e-06 28.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KEY69206.1 - 3.8e-07 30.4 0.1 1.1e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KEY69206.1 - 8e-06 25.7 0.1 2.3e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.6 KEY69206.1 - 1.3e-05 25.8 0.0 4.9e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEY69206.1 - 0.00021 20.7 0.4 0.00063 19.2 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KEY69206.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KEY69206.1 - 0.0015 18.3 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase adh_short PF00106.25 KEY69206.1 - 0.0016 17.9 0.1 0.0075 15.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NodS PF05401.11 KEY69206.1 - 0.024 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF4084 PF13321.6 KEY69206.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) NmrA PF05368.13 KEY69206.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family SAT PF16073.5 KEY69206.1 - 0.072 12.8 1.7 1.5 8.5 1.7 2.5 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis MFS_1 PF07690.16 KEY69207.1 - 1.3e-22 80.2 62.6 1.8e-21 76.5 62.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 KEY69208.1 - 8e-34 117.1 0.0 1.3e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 KEY69209.1 - 6.6e-21 74.5 4.1 6.6e-21 74.5 4.1 1.8 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_7 PF00840.20 KEY69210.1 - 5e-171 569.2 5.3 6.7e-171 568.8 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Toxin_11 PF07473.11 KEY69210.1 - 0.27 11.3 3.6 1.3 9.1 3.6 2.2 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Prenyltrans PF00432.21 KEY69211.1 - 1.3e-36 124.0 10.1 3.4e-08 33.1 0.2 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KEY69211.1 - 4.8e-05 22.6 0.1 0.0067 15.6 0.0 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain Ilm1 PF10311.9 KEY69212.1 - 4.2e-62 208.7 0.2 4.7e-62 208.5 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 SecD_SecF PF02355.16 KEY69212.1 - 1.9 7.8 4.5 0.57 9.5 0.1 2.2 3 1 0 3 3 3 0 Protein export membrane protein Pkinase PF00069.25 KEY69213.1 - 3.8e-66 223.2 0.0 5e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69213.1 - 4e-40 137.7 0.0 5.8e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY69213.1 - 3e-08 33.3 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEY69213.1 - 1.8e-05 23.8 0.2 1.8e-05 23.8 0.2 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KEY69213.1 - 0.011 15.0 0.0 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY69213.1 - 0.059 13.3 2.4 0.062 13.2 0.1 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEY69213.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KEY69213.1 - 0.16 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family SNF2_N PF00176.23 KEY69214.1 - 5e-67 226.1 0.3 8e-67 225.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY69214.1 - 2.7e-19 69.5 0.0 2.7e-18 66.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY69214.1 - 2e-09 37.7 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEY69214.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.13 KEY69214.1 - 0.0036 17.6 10.7 0.0036 17.6 10.7 2.9 2 1 0 2 2 2 1 HSA HDA2-3 PF11496.8 KEY69214.1 - 0.02 14.0 0.1 2.4 7.3 0.0 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 NDUF_B8 PF05821.11 KEY69215.1 - 9.2e-07 28.9 1.0 1.4e-06 28.3 1.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) TRAPPC10 PF12584.8 KEY69217.1 - 2.9e-27 95.3 0.0 4.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KEY69217.1 - 0.0015 18.2 0.2 0.0026 17.4 0.2 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.17 KEY69218.1 - 1.6e-75 253.9 1.0 1.9e-75 253.7 1.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1786 PF08735.10 KEY69218.1 - 0.077 12.3 0.4 9.8 5.4 0.1 2.8 3 0 0 3 3 3 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Phage_GP20 PF06810.11 KEY69218.1 - 0.091 12.6 1.4 0.15 11.8 1.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Peptidase_M20 PF01546.28 KEY69219.1 - 4e-18 65.9 3.9 1.2e-17 64.3 3.9 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY69219.1 - 3.2e-16 59.2 0.0 5.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEY69219.1 - 0.00026 20.7 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KEY69219.1 - 0.014 14.5 0.2 0.068 12.2 0.1 1.9 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase ACP_syn_III_C PF08541.10 KEY69219.1 - 0.082 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2205 PF10224.9 KEY69220.1 - 2.4e-36 123.6 0.7 3.5e-36 123.0 0.7 1.2 1 0 0 1 1 1 1 Short coiled-coil protein AAA_32 PF13654.6 KEY69220.1 - 0.055 12.2 0.0 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.17 KEY69221.1 - 2.6e-37 128.4 0.0 3.6e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY69221.1 - 1.9e-11 43.8 0.3 4.3e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY69221.1 - 3.6e-05 23.6 0.0 8.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Csm1_N PF18504.1 KEY69223.1 - 0.94 9.9 6.1 3.5 8.1 1.3 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF2390 PF09523.10 KEY69223.1 - 5.7 7.3 8.2 1.4 9.3 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Glyco_hydro_43 PF04616.14 KEY69224.1 - 1.4e-32 113.2 0.5 2.1e-32 112.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY69224.1 - 1.3e-21 77.3 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain peroxidase PF00141.23 KEY69226.1 - 3.6e-31 108.6 0.1 5.2e-31 108.1 0.1 1.2 1 0 0 1 1 1 1 Peroxidase p450 PF00067.22 KEY69227.1 - 3.9e-69 233.6 0.0 4.9e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SDH_alpha PF03313.15 KEY69228.1 - 7.2e-99 330.7 0.2 9.3e-99 330.3 0.2 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KEY69228.1 - 2.6e-56 190.3 0.0 6e-56 189.1 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Glyco_hydro_6 PF01341.17 KEY69229.1 - 1.1e-95 320.9 0.0 1.5e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Peptidase_M28 PF04389.17 KEY69230.1 - 2e-34 119.0 0.0 3.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY69230.1 - 1.2e-07 31.7 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY69230.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KEY69230.1 - 0.19 10.7 0.0 0.37 9.7 0.0 1.4 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase adh_short PF00106.25 KEY69231.1 - 2.7e-37 128.1 0.3 3.6e-37 127.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69231.1 - 9.6e-31 107.1 0.7 1.2e-30 106.8 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KEY69231.1 - 3.9e-05 23.6 0.2 8.1e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 KEY69231.1 - 4.1e-05 23.6 0.2 8.3e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY69231.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KEY69231.1 - 0.0031 17.4 0.3 0.0053 16.7 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY69231.1 - 0.051 13.0 0.1 0.094 12.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KEY69231.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2OG-FeII_Oxy_3 PF13640.6 KEY69232.1 - 2.6e-09 37.9 0.0 4.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Senescence PF06911.12 KEY69232.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein APH PF01636.23 KEY69233.1 - 7.2e-14 52.3 0.0 1.5e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY69233.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4853 PF16145.5 KEY69233.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4853) NAD_binding_8 PF13450.6 KEY69234.1 - 1.8e-09 37.7 0.1 4.9e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY69234.1 - 1.8e-09 37.2 0.0 2.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY69234.1 - 5.3e-08 31.7 0.1 2.1e-07 29.7 0.0 1.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY69234.1 - 1.5e-07 31.0 0.0 1.1e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY69234.1 - 0.00014 21.0 0.5 0.00023 20.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KEY69234.1 - 0.00023 20.5 1.1 0.33 10.1 1.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEY69234.1 - 0.0006 19.5 2.0 0.0051 16.4 0.4 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY69234.1 - 0.00094 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KEY69234.1 - 0.0043 16.2 0.4 0.2 10.7 0.6 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KEY69234.1 - 0.0065 15.6 0.2 0.047 12.8 0.2 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEY69234.1 - 0.0069 15.7 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEY69234.1 - 0.031 13.0 1.3 0.052 12.2 1.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Integrin_b_cyt PF08725.11 KEY69234.1 - 0.062 13.0 0.3 0.17 11.6 0.3 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain NAD_binding_9 PF13454.6 KEY69234.1 - 0.15 12.0 0.8 0.71 9.8 0.3 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KEY69234.1 - 2.1 7.6 4.9 3 7.1 3.9 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KEY69235.1 - 2.2e-44 152.5 0.6 2.7e-44 152.2 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY69235.1 - 5.8e-05 23.1 1.7 0.0086 16.1 0.1 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEY69235.1 - 0.0009 18.6 0.1 0.0023 17.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY69235.1 - 0.02 14.2 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY69235.1 - 0.033 13.3 0.0 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Aldedh PF00171.22 KEY69236.1 - 1.2e-138 462.5 0.1 1.5e-114 383.1 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DAO PF01266.24 KEY69237.1 - 2.5e-16 60.2 0.1 1.5e-08 34.6 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY69237.1 - 0.14 10.8 0.2 0.21 10.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KEY69237.1 - 0.15 12.3 0.2 0.48 10.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 KEY69238.1 - 5.7e-161 536.1 0.0 7.1e-161 535.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KEY69239.1 - 1e-45 156.4 0.0 1.5e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY69239.1 - 4.8e-40 137.4 0.0 8e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEY69239.1 - 4.1e-05 22.8 0.3 7.5e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY69239.1 - 0.00012 21.8 0.3 0.0066 16.1 0.7 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY69239.1 - 0.00013 21.2 0.3 0.45 9.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY69239.1 - 0.00085 19.5 0.4 0.0023 18.1 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY69239.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY69239.1 - 0.0073 15.6 0.1 0.023 14.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GDI PF00996.18 KEY69239.1 - 0.0092 14.6 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Trp_halogenase PF04820.14 KEY69239.1 - 0.031 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KEY69239.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.22 KEY69240.1 - 1.3e-45 156.0 0.0 1.7e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KEY69241.1 - 6.1e-36 124.1 0.0 7.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY69241.1 - 6.4e-13 49.0 0.0 1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY69241.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEY69241.1 - 0.00042 20.6 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KEY69241.1 - 0.0034 16.4 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KEY69241.1 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY69241.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KEY69242.1 - 1.7e-20 73.2 0.5 6.5e-12 44.9 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69242.1 - 0.0031 17.6 1.0 0.0031 17.6 1.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 KEY69243.1 - 1.5e-17 64.2 0.0 6e-13 49.1 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Ammonium_transp PF00909.21 KEY69247.1 - 5.3e-99 331.6 25.0 6.5e-99 331.3 25.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sugar_tr PF00083.24 KEY69249.1 - 2.8e-75 253.9 21.4 3.3e-75 253.7 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69249.1 - 1.6e-25 89.8 27.2 2.7e-22 79.2 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3445 PF11927.8 KEY69250.1 - 2.3e-75 253.1 0.0 3.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PBP PF01161.20 KEY69250.1 - 4.2e-07 30.3 0.0 4.2e-06 27.1 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylethanolamine-binding protein zf_C2H2_ZHX PF18387.1 KEY69251.1 - 0.019 14.6 0.5 0.058 13.0 0.5 1.9 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KEY69251.1 - 1.2 9.0 3.2 0.58 10.0 0.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Glyco_hydro_61 PF03443.14 KEY69252.1 - 5.2e-50 170.3 0.0 6.3e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Extensin_2 PF04554.13 KEY69254.1 - 0.1 12.7 2.6 0.22 11.7 2.6 1.5 1 0 0 1 1 1 0 Extensin-like region Trypsin PF00089.26 KEY69255.1 - 1.5e-10 41.2 0.0 2.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KEY69255.1 - 6.2e-08 33.7 0.2 1e-07 33.0 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.16 KEY69256.1 - 1.2e-23 83.6 54.3 1.8e-12 46.9 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY69256.1 - 0.14 11.0 23.3 0.1 11.4 1.2 2.4 3 0 0 3 3 3 0 MFS_1 like family Tannase PF07519.11 KEY69257.1 - 2.4e-93 313.6 0.1 2.7e-93 313.4 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase RNA_pol_A_CTD PF03118.15 KEY69257.1 - 0.19 11.5 0.1 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Glyco_hydro_61 PF03443.14 KEY69258.1 - 2.8e-58 197.2 0.0 3.4e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.21 KEY69259.1 - 1.8e-97 326.9 40.9 2.2e-97 326.6 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY69259.1 - 1.5e-30 106.4 45.3 1.7e-30 106.2 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease PI-PLC-X PF00388.19 KEY69260.1 - 1.3e-39 135.1 0.0 2e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEY69260.1 - 4.9e-37 126.8 0.0 7.7e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Stealth_CR1 PF17101.5 KEY69261.1 - 1 9.1 5.7 28 4.6 0.1 4.2 4 0 0 4 4 4 0 Stealth protein CR1, conserved region 1 Omega-toxin PF06357.11 KEY69261.1 - 1.8 8.4 17.9 14 5.6 0.1 5.8 6 0 0 6 6 6 0 Omega-atracotoxin Resistin PF06954.11 KEY69262.1 - 0.086 13.4 0.3 0.086 13.4 0.3 3.0 3 0 0 3 3 3 0 Resistin Phytase PF02333.15 KEY69263.1 - 2.5e-70 237.4 0.0 6e-70 236.1 0.0 1.5 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.13 KEY69263.1 - 8.8e-06 26.0 34.3 0.0087 16.4 14.2 2.6 2 0 0 2 2 2 2 EGF-like domain Amidoligase_2 PF12224.8 KEY69264.1 - 2.7e-08 33.8 0.0 8e-05 22.4 0.0 2.7 2 1 0 2 2 2 2 Putative amidoligase enzyme WD40 PF00400.32 KEY69265.1 - 1.6e-58 193.3 36.9 4.9e-11 43.0 1.5 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69265.1 - 7.6e-23 80.6 5.1 3.4e-05 24.1 0.0 6.3 3 3 4 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY69265.1 - 7.4e-07 28.4 0.1 2.3 7.1 0.0 5.9 3 3 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEY69265.1 - 5.1e-06 26.5 0.2 0.0067 16.3 0.0 3.2 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KEY69265.1 - 2.4e-05 24.1 1.3 0.24 11.4 0.0 4.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KEY69265.1 - 0.0015 17.3 0.9 2.9 6.4 0.8 4.1 4 1 0 4 4 4 1 Nucleoporin Nup120/160 NLE PF08154.12 KEY69265.1 - 0.003 18.0 0.0 0.0074 16.8 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 KEY69265.1 - 0.0038 16.6 0.0 2.9 7.1 0.0 3.2 4 1 0 4 4 4 2 WD40-like domain Proteasome_A_N PF10584.9 KEY69265.1 - 0.011 15.4 0.2 5.5 6.8 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Glyco_transf_20 PF00982.21 KEY69266.1 - 1.1e-166 555.3 0.1 1.5e-166 554.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KEY69266.1 - 8e-49 165.9 0.0 1.5e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KEY69266.1 - 0.00015 21.6 0.0 0.057 13.1 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 KEY69266.1 - 0.04 13.6 0.4 0.089 12.5 0.4 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain HNOB PF07700.15 KEY69266.1 - 0.078 12.9 0.2 0.18 11.8 0.1 1.6 2 0 0 2 2 2 0 Haem-NO-binding Aminotran_4 PF01063.19 KEY69267.1 - 1.1e-22 81.0 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV FAR1 PF03101.15 KEY69268.1 - 4.7e-05 24.0 0.3 4.7e-05 24.0 0.3 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain NP1-WLL PF11733.8 KEY69268.1 - 0.022 14.6 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Non-capsid protein NP1 TFIIA PF03153.13 KEY69268.1 - 0.16 11.9 24.1 0.2 11.6 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_U57 PF05582.12 KEY69268.1 - 0.36 10.0 5.2 0.52 9.5 5.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Rrn6 PF10214.9 KEY69268.1 - 0.47 8.9 15.3 0.58 8.6 15.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor eIF-3_zeta PF05091.12 KEY69268.1 - 3.6 6.5 11.9 5 6.0 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hydin_ADK PF17213.3 KEY69268.1 - 4.2 7.6 10.6 7.7 6.7 10.6 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SPX PF03105.19 KEY69268.1 - 5.8 6.7 13.7 1.8 8.4 10.5 1.7 2 0 0 2 2 2 0 SPX domain PEHE PF15275.6 KEY69268.1 - 6.3 7.4 14.1 8.7 7.0 11.9 2.1 2 0 0 2 2 2 0 PEHE domain PIEZO PF15917.5 KEY69268.1 - 7.8 5.9 15.5 3.6 7.0 13.0 1.6 2 0 0 2 2 2 0 Piezo AFT PF08731.11 KEY69268.1 - 8.9 6.8 13.2 0.11 12.9 0.6 2.9 2 2 0 2 2 2 0 Transcription factor AFT MutS_III PF05192.18 KEY69269.1 - 2.4e-29 102.9 2.5 5.5e-28 98.5 2.5 2.3 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KEY69269.1 - 9.9e-08 32.2 0.1 1.9e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KEY69269.1 - 0.00018 21.8 0.1 0.00073 19.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_V PF00488.21 KEY69270.1 - 7.7e-59 198.9 0.2 9.5e-59 198.6 0.2 1.1 1 0 0 1 1 1 1 MutS domain V Dynamin_N PF00350.23 KEY69271.1 - 1.9e-31 109.4 0.0 5e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEY69271.1 - 2.1e-13 50.2 0.0 9.2e-13 48.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KEY69271.1 - 4.6e-05 23.5 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Drf_FH3 PF06367.16 KEY69271.1 - 0.11 12.1 1.3 0.22 11.1 1.3 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain ABC_tran PF00005.27 KEY69271.1 - 0.36 11.3 0.0 0.36 11.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Menin PF05053.13 KEY69271.1 - 8.8 4.5 7.9 12 4.1 7.9 1.1 1 0 0 1 1 1 0 Menin Cation_efflux PF01545.21 KEY69272.1 - 4.6e-23 82.0 4.2 5.9e-23 81.6 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEY69272.1 - 3.5e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FAD_binding_4 PF01565.23 KEY69274.1 - 3.8e-22 78.5 1.0 6.7e-22 77.7 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69274.1 - 1.9e-10 40.6 0.0 4.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like EutQ PF06249.12 KEY69275.1 - 8.7e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KEY69275.1 - 6.4e-09 35.4 0.0 1.3e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KEY69275.1 - 0.0008 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KEY69275.1 - 0.025 14.3 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Cupin KduI PF04962.12 KEY69275.1 - 0.056 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Pirin PF02678.16 KEY69275.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Pirin DUF3445 PF11927.8 KEY69276.1 - 8.1e-77 257.8 0.0 1e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RsbU_N PF08673.10 KEY69276.1 - 0.29 11.3 0.7 0.71 10.0 0.1 1.9 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Fungal_trans_2 PF11951.8 KEY69277.1 - 9.9e-27 93.7 0.5 1.6e-21 76.6 1.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69277.1 - 5.6e-07 29.6 11.2 9.3e-07 28.9 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caleosin PF05042.13 KEY69278.1 - 2.5e-66 222.8 0.1 3e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KEY69278.1 - 0.00069 19.4 1.8 0.61 10.2 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEY69278.1 - 0.023 14.2 1.9 0.33 10.6 0.0 2.7 3 0 0 3 3 3 0 EF hand Thioredoxin_7 PF13899.6 KEY69279.1 - 2.2e-17 63.0 0.1 5.3e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KEY69279.1 - 5.5e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KEY69279.1 - 2.1e-09 37.4 0.0 3.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 KEY69279.1 - 0.01 15.8 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KEY69279.1 - 0.027 14.9 0.1 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain CUE PF02845.16 KEY69279.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain Iso_dh PF00180.20 KEY69280.1 - 1.3e-81 274.5 0.0 2.2e-81 273.7 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 KEY69280.1 - 1.1e-68 231.5 0.0 1.8e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69280.1 - 4.1e-50 170.5 0.0 7.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY69280.1 - 0.0016 17.3 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEY69280.1 - 0.076 12.3 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.16 KEY69281.1 - 7.7e-28 97.4 27.6 1.7e-14 53.6 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY69281.1 - 6.3e-05 22.0 16.5 0.0016 17.4 7.9 2.3 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KEY69281.1 - 0.00089 18.2 14.3 0.0043 16.0 14.3 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KEY69281.1 - 0.014 13.7 10.6 0.14 10.4 0.1 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4148 PF13663.6 KEY69281.1 - 0.064 13.4 0.7 0.73 10.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FAM176 PF14851.6 KEY69281.1 - 0.065 12.9 0.1 2.5 7.8 0.0 2.8 3 0 0 3 3 3 0 FAM176 family peroxidase PF00141.23 KEY69282.1 - 3e-14 53.3 0.6 2.7e-13 50.1 0.1 2.0 2 0 0 2 2 2 1 Peroxidase PSI_PSAK PF01241.18 KEY69282.1 - 0.0089 16.0 0.1 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Photosystem I psaG / psaK NOA36 PF06524.12 KEY69282.1 - 3.9 6.7 6.4 5.7 6.2 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1295 PF06966.12 KEY69283.1 - 9e-31 107.2 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KEY69283.1 - 0.0058 16.2 0.0 0.027 14.0 0.0 2.0 1 1 1 2 2 2 1 NnrU protein ICMT PF04140.14 KEY69283.1 - 0.0081 16.6 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KEY69283.1 - 0.035 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Aminotran_1_2 PF00155.21 KEY69284.1 - 8.2e-43 147.0 0.0 9.8e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HAD_2 PF13419.6 KEY69285.1 - 2.7e-12 47.1 0.0 3.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY69285.1 - 1.4e-11 45.1 0.0 4.3e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY69285.1 - 2.1e-07 30.9 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3226 PF11536.8 KEY69285.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) tRNA-synt_2 PF00152.20 KEY69286.1 - 1.9e-75 253.9 0.2 2.5e-75 253.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KEY69286.1 - 4.2e-07 29.7 0.2 0.00098 18.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KEY69286.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WBS_methylT PF12589.8 KEY69287.1 - 4.7e-14 52.9 2.7 9.3e-14 51.9 2.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KEY69287.1 - 4.6e-11 43.2 0.0 8.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69287.1 - 4.3e-10 40.2 0.0 1.3e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY69287.1 - 6.5e-05 22.8 0.0 0.00017 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KEY69287.1 - 0.00011 22.9 0.0 0.00034 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69287.1 - 0.00038 20.3 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69287.1 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEY69287.1 - 0.0031 16.8 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KEY69287.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Erv26 PF04148.13 KEY69288.1 - 1.7e-90 302.4 0.5 2e-90 302.2 0.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM43 PF07787.12 KEY69288.1 - 0.65 9.3 2.6 1.2 8.4 2.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 ADH_zinc_N PF00107.26 KEY69290.1 - 2.5e-08 34.0 0.0 4.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY69290.1 - 1e-07 31.8 0.0 7.8e-07 29.0 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY69290.1 - 6.6e-06 27.2 0.0 2.1e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.16 KEY69291.1 - 3.9e-24 85.0 0.0 5.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEY69291.1 - 3.5e-19 69.2 0.0 6.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KEY69291.1 - 0.017 14.5 0.4 0.063 12.6 0.2 1.9 2 0 0 2 2 2 0 ThiF family Oxidored_FMN PF00724.20 KEY69292.1 - 2.4e-90 303.3 0.0 2.7e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 KEY69293.1 - 1.8e-23 83.3 0.0 6.2e-13 48.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69293.1 - 6.7e-08 32.1 0.1 0.0039 16.5 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase Glyco_hydro_43 PF04616.14 KEY69295.1 - 5.8e-10 39.0 1.2 1e-09 38.1 0.5 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KEY69295.1 - 0.0028 17.3 0.0 0.0065 16.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain GST_N PF02798.20 KEY69296.1 - 5.7e-13 49.0 0.0 9.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY69296.1 - 7.1e-11 42.2 0.0 1.6e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY69296.1 - 1.5e-10 41.3 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY69296.1 - 1.6e-09 38.0 0.0 3.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY69296.1 - 3.8e-07 30.2 0.1 9.6e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY69296.1 - 2.1e-05 24.5 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KEY69296.1 - 4e-05 23.9 0.0 7.9e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KEY69296.1 - 0.0033 18.2 0.0 0.0058 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEY69296.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Phospholip_A2_3 PF09056.11 KEY69297.1 - 9e-44 148.7 0.2 1.1e-43 148.3 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Ank PF00023.30 KEY69299.1 - 1.4e-05 25.3 0.0 4.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KEY69299.1 - 2.8e-05 24.6 0.0 9.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY69299.1 - 0.00039 20.6 0.0 0.0024 18.2 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KEY69299.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Amidase PF01425.21 KEY69300.1 - 3.9e-83 279.9 0.0 1.1e-82 278.4 0.0 1.6 1 1 0 1 1 1 1 Amidase Ecm29 PF13001.7 KEY69301.1 - 2.3e-142 475.2 0.2 1.7e-141 472.3 0.0 2.6 3 0 0 3 3 3 1 Proteasome stabiliser Sec7_N PF12783.7 KEY69301.1 - 0.029 14.3 2.9 1 9.3 0.2 3.4 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_2 PF13646.6 KEY69301.1 - 0.053 13.9 10.2 0.35 11.3 0.1 5.6 5 1 1 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 KEY69301.1 - 0.39 11.3 12.0 26 5.5 0.0 7.4 8 1 1 9 9 9 0 HEAT-like repeat HEAT PF02985.22 KEY69301.1 - 0.45 10.9 12.9 7 7.2 0.0 6.5 6 0 0 6 6 6 0 HEAT repeat Sun2_CC2 PF18580.1 KEY69301.1 - 0.57 10.5 2.7 0.99 9.7 0.4 2.8 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 RRM_1 PF00076.22 KEY69302.1 - 1.9e-45 152.5 0.0 1.4e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY69302.1 - 1.2e-05 25.2 0.3 0.0023 17.9 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEY69302.1 - 5.9e-05 22.8 0.0 0.052 13.4 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KEY69302.1 - 0.00016 21.7 0.0 0.0018 18.3 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KEY69302.1 - 0.00017 21.7 0.0 0.054 13.6 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KEY69302.1 - 0.022 14.3 0.0 0.11 12.1 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4HBT_3 PF13622.6 KEY69303.1 - 4.4e-26 92.7 0.0 7.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4625 PF15418.6 KEY69303.1 - 0.037 14.3 0.0 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Cyclase PF04199.13 KEY69305.1 - 2.3e-18 66.7 0.0 3.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 KEY69306.1 - 3.5e-58 196.9 0.2 5e-58 196.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69306.1 - 1.1e-41 142.4 0.1 1.5e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69306.1 - 1.8e-08 34.5 0.1 3e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY69306.1 - 0.031 13.4 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MGC-24 PF05283.11 KEY69306.1 - 0.1 13.0 4.4 0.19 12.2 4.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1776 PF08643.10 KEY69306.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY69306.1 - 0.12 11.8 0.2 0.24 10.8 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Archaeal_AmoA PF12942.7 KEY69307.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) SOR_SNZ PF01680.17 KEY69308.1 - 2.2e-105 351.0 7.4 2.8e-105 350.6 7.4 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KEY69308.1 - 9.8e-10 38.2 4.2 3.3e-07 29.9 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KEY69308.1 - 0.00011 22.3 0.0 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KEY69308.1 - 0.00011 21.5 0.4 0.2 10.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KEY69308.1 - 0.00025 20.6 0.6 0.089 12.2 0.0 3.1 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 KEY69308.1 - 0.00085 18.6 0.4 0.02 14.0 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KEY69308.1 - 0.0028 16.8 0.8 0.13 11.5 0.0 2.8 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KEY69308.1 - 0.0083 15.5 0.7 0.47 9.8 0.1 2.6 2 1 0 2 2 2 1 Thiamine monophosphate synthase NMO PF03060.15 KEY69308.1 - 0.0099 15.3 9.7 0.21 10.9 2.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase DUF4398 PF14346.6 KEY69308.1 - 0.023 15.3 1.0 0.023 15.3 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) OMPdecase PF00215.24 KEY69308.1 - 0.071 12.7 1.4 0.1 12.2 0.4 1.7 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SNO PF01174.19 KEY69309.1 - 1.2e-52 178.6 0.0 1.5e-50 171.6 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KEY69309.1 - 8.1e-09 35.4 0.0 8.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KEY69309.1 - 0.0034 17.2 0.0 0.038 13.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEY69309.1 - 0.0039 17.0 0.0 0.0091 15.8 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KEY69309.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Ank_2 PF12796.7 KEY69310.1 - 3.5e-36 123.6 1.8 5.2e-11 43.0 0.0 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY69310.1 - 3.4e-33 113.6 1.6 3.4e-07 30.7 0.0 8.7 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY69310.1 - 2.5e-28 97.7 3.1 1.5e-05 25.1 0.0 8.0 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69310.1 - 8.1e-27 90.3 0.3 0.016 15.7 0.0 10.5 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 KEY69310.1 - 2.1e-19 69.0 7.9 0.0011 19.3 0.0 10.2 10 1 0 10 10 10 5 Ankyrin repeat Chal_sti_synt_N PF00195.19 KEY69311.1 - 4.1e-27 95.1 0.1 6e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KEY69311.1 - 5.9e-21 75.0 0.0 2.6e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KEY69311.1 - 1e-05 25.6 0.0 5.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KEY69311.1 - 1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KEY69311.1 - 0.0013 18.6 0.1 0.0033 17.2 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HpcH_HpaI PF03328.14 KEY69312.1 - 2.5e-23 82.4 0.0 3.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Stealth_CR1 PF17101.5 KEY69312.1 - 0.24 11.1 0.9 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 SGL PF08450.12 KEY69313.1 - 0.0005 19.7 0.0 0.0018 17.9 0.0 1.9 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ketoacyl-synt PF00109.26 KEY69314.1 - 1.7e-79 267.0 0.0 3.1e-79 266.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY69314.1 - 3.7e-69 233.7 0.1 7.2e-69 232.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY69314.1 - 2.8e-61 206.6 0.1 2.2e-59 200.4 0.0 2.6 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEY69314.1 - 4.4e-36 123.5 0.4 1.7e-35 121.6 0.4 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY69314.1 - 3.4e-13 50.0 0.0 1.2e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY69314.1 - 4.8e-10 39.6 0.0 1.9e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KEY69314.1 - 3e-08 33.3 0.0 1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 KEY69314.1 - 5.5e-06 26.0 0.0 0.00037 20.0 0.0 3.2 3 1 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KEY69314.1 - 0.00024 20.6 0.1 0.0007 19.0 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain DHDPS PF00701.22 KEY69315.1 - 5.6e-46 156.6 0.0 6.9e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank_2 PF12796.7 KEY69316.1 - 1.1e-13 51.6 0.0 1.4e-08 35.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY69316.1 - 1.9e-11 43.1 0.0 0.0021 18.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KEY69316.1 - 1.1e-06 29.1 0.0 0.0017 18.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY69316.1 - 6.7e-06 26.3 0.3 0.00089 19.5 0.1 3.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY69316.1 - 4.7e-05 23.6 0.6 0.051 14.0 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeat DctQ PF04290.12 KEY69316.1 - 0.051 13.5 1.7 0.12 12.3 0.6 2.1 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Glyco_transf_54 PF04666.13 KEY69317.1 - 2.3e-13 49.6 0.0 4.5e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_90 PF05686.12 KEY69318.1 - 6.7e-14 51.6 0.0 2.1e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_2_N PF02837.18 KEY69319.1 - 1.9e-13 50.7 0.1 8.8e-13 48.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KEY69319.1 - 2e-08 34.9 0.0 9.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KEY69319.1 - 3.4e-07 29.7 0.1 2.7e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain TFX_C PF14601.6 KEY69319.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 DNA_binding protein, TFX, C-term ATP-grasp PF02222.22 KEY69320.1 - 2e-18 66.6 0.0 3.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KEY69320.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Ctr PF04145.15 KEY69321.1 - 6.9e-39 133.8 1.7 8.3e-39 133.6 1.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KEY69321.1 - 0.94 9.2 8.3 6.2 6.5 6.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ferric_reduct PF01794.19 KEY69322.1 - 8.6e-23 80.8 9.0 2.4e-22 79.4 9.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY69322.1 - 1.8e-18 67.2 0.0 2.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY69322.1 - 6.3e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KEY69322.1 - 3e-06 27.8 0.0 8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAGidase PF07555.13 KEY69322.1 - 0.26 10.6 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase VIT PF08487.10 KEY69324.1 - 3.3e-31 107.8 0.0 1.4e-30 105.7 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KEY69324.1 - 1e-27 97.0 0.0 2.1e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KEY69324.1 - 8.6e-17 60.8 0.1 2.4e-16 59.4 0.1 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KEY69324.1 - 6.4e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEY69324.1 - 2.3e-09 37.8 0.0 6.4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KEY69324.1 - 0.00062 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein adh_short_C2 PF13561.6 KEY69325.1 - 2e-52 178.1 0.1 2.4e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69325.1 - 5.9e-51 172.7 0.1 7e-51 172.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY69325.1 - 4e-13 49.7 0.2 6.4e-13 49.0 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69325.1 - 0.0009 18.8 0.1 0.0014 18.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 KEY69325.1 - 0.0059 16.3 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain ADH_zinc_N PF00107.26 KEY69325.1 - 0.023 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KEY69325.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KEY69325.1 - 0.21 11.5 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHDPS PF00701.22 KEY69326.1 - 9.1e-42 142.7 0.0 1.1e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF442 PF04273.13 KEY69326.1 - 0.12 12.4 0.0 0.5 10.5 0.0 2.0 1 1 1 2 2 2 0 Putative phosphatase (DUF442) ApbA PF02558.16 KEY69327.1 - 5e-33 113.9 0.1 6.7e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEY69327.1 - 2.3e-29 102.1 0.0 3.6e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 KEY69327.1 - 0.0036 17.6 0.1 0.014 15.6 0.1 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain eIF-5a PF01287.20 KEY69327.1 - 0.033 14.3 0.0 5.8 7.1 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FMN_dh PF01070.18 KEY69328.1 - 2.2e-99 332.8 0.0 3.1e-99 332.3 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEY69328.1 - 2.5e-19 69.2 0.0 6.8e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEY69328.1 - 1.3e-06 27.8 0.1 1.9e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY69328.1 - 0.0033 16.5 2.5 0.0053 15.8 0.9 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEY69328.1 - 0.027 13.8 0.3 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FAD_binding_4 PF01565.23 KEY69329.1 - 1.9e-22 79.5 2.7 3.4e-22 78.7 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain ATP-grasp_3 PF02655.14 KEY69330.1 - 0.0045 17.0 0.0 0.027 14.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.16 KEY69331.1 - 4.6e-20 71.8 44.9 4.6e-20 71.8 44.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3894 PF13033.6 KEY69331.1 - 7.8 6.7 8.2 20 5.4 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3894) Acetyltransf_10 PF13673.7 KEY69332.1 - 1.1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY69332.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY69332.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY69332.1 - 0.00045 20.3 0.0 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY69332.1 - 0.0012 18.8 0.1 0.0028 17.6 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KEY69332.1 - 0.027 14.5 0.0 0.1 12.7 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_106 PF17132.4 KEY69333.1 - 3.4e-37 128.2 0.0 1.9e-28 99.2 0.0 2.1 1 1 1 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 KEY69333.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Carb_anhydrase PF00194.21 KEY69334.1 - 2.6e-25 89.4 0.0 1e-11 44.9 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 KEY69336.1 - 8.4e-60 199.3 0.0 6.5e-11 42.7 0.1 7.4 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY69336.1 - 1e-47 159.9 0.0 6.1e-07 29.9 0.0 12.0 7 3 7 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69336.1 - 1.6e-42 138.6 0.2 0.00035 20.8 0.0 14.9 16 0 0 16 16 16 8 Ankyrin repeat Ank_5 PF13857.6 KEY69336.1 - 3.6e-41 138.7 0.8 3.4e-06 27.2 0.0 8.2 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KEY69336.1 - 2.8e-34 116.0 2.6 0.006 17.0 0.0 14.5 15 1 0 15 15 15 8 Ankyrin repeat AMP-binding PF00501.28 KEY69338.1 - 1.2e-93 314.0 0.0 1.5e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY69338.1 - 2e-23 83.2 0.6 4.2e-23 82.1 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HRXXH PF13933.6 KEY69339.1 - 4.6e-102 340.8 0.0 7.1e-102 340.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Glyco_tranf_2_3 PF13641.6 KEY69341.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NACHT PF05729.12 KEY69342.1 - 1.7e-07 31.3 0.0 4.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KEY69342.1 - 0.0015 18.3 0.0 0.0056 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain HSBP1 PF06825.12 KEY69342.1 - 0.0064 16.3 0.9 3.8 7.4 0.0 4.0 3 0 0 3 3 3 1 Heat shock factor binding protein 1 Helo_like_N PF17111.5 KEY69342.1 - 0.013 14.9 0.0 0.062 12.7 0.0 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KEY69342.1 - 0.017 15.5 0.0 0.069 13.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain SesA PF17107.5 KEY69342.1 - 0.018 15.2 0.0 0.083 13.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 KEY69342.1 - 0.018 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KEY69342.1 - 0.019 14.2 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 KEY69342.1 - 0.024 14.9 0.1 0.17 12.2 0.1 2.4 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEY69342.1 - 0.034 14.7 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KEY69342.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KEY69342.1 - 0.14 12.7 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KEY69346.1 - 3.1e-27 95.7 0.1 4.5e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_C PF00043.25 KEY69347.1 - 5.5e-17 61.8 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY69347.1 - 6.5e-13 48.7 0.0 1.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY69347.1 - 9.7e-13 48.3 0.0 2.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY69347.1 - 6.4e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY69347.1 - 1.3e-08 35.0 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY69347.1 - 3.8e-08 33.2 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CFEM PF05730.11 KEY69349.1 - 1.8e-13 50.4 13.7 3.2e-13 49.6 13.7 1.4 1 0 0 1 1 1 1 CFEM domain zf-C5HC2 PF02928.16 KEY69349.1 - 9.1 6.8 8.2 1.6 9.2 3.6 2.1 2 0 0 2 2 2 0 C5HC2 zinc finger adh_short PF00106.25 KEY69350.1 - 7.8e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69350.1 - 0.0029 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KEY69350.1 - 0.45 10.3 2.8 0.97 9.2 2.8 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.18 KEY69351.1 - 3.4e-08 33.5 9.9 6.7e-08 32.5 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3419 PF11899.8 KEY69351.1 - 0.02 14.1 0.8 0.03 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) Peptidase_M28 PF04389.17 KEY69352.1 - 4.2e-41 140.8 0.0 5.9e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY69352.1 - 5.4e-09 36.0 0.0 7.4e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KEY69352.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 KEY69352.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Lipase_3 PF01764.25 KEY69353.1 - 1.6e-30 105.9 0.0 2.3e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KEY69353.1 - 8.2e-06 25.8 0.1 1.5e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KEY69353.1 - 9e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KEY69353.1 - 0.00022 20.8 0.0 0.0091 15.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 KEY69353.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY69353.1 - 0.003 18.2 0.2 0.004 17.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEY69353.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KEY69353.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.20 KEY69353.1 - 0.057 13.5 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain adh_short PF00106.25 KEY69354.1 - 4.7e-32 111.0 0.4 7e-32 110.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69354.1 - 1.7e-26 93.2 0.3 2.4e-26 92.8 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69354.1 - 9.6e-08 32.1 0.2 1.5e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69354.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AIRC PF00731.20 KEY69354.1 - 0.0032 17.0 0.6 0.015 14.9 0.2 2.2 2 1 0 2 2 2 1 AIR carboxylase Eno-Rase_NADH_b PF12242.8 KEY69354.1 - 0.18 11.6 1.2 0.73 9.6 0.1 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidase PF01425.21 KEY69355.1 - 1.1e-76 258.7 0.0 1.6e-76 258.1 0.0 1.3 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.18 KEY69355.1 - 0.00052 20.1 11.5 0.0013 18.8 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KEY69356.1 - 1.4e-67 227.3 6.8 1.4e-67 227.3 6.8 1.7 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KEY69357.1 - 0.00047 20.2 11.2 0.0011 19.0 1.4 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY69357.1 - 0.0019 17.1 0.3 0.0027 16.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69358.1 - 1.5e-08 34.7 9.1 1.5e-08 34.7 9.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY69358.1 - 8.4e-08 31.6 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY69359.1 - 1.9e-35 122.4 49.8 8e-23 80.9 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY69359.1 - 5.8e-05 22.1 30.8 0.00033 19.6 12.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 KEY69359.1 - 0.028 14.8 6.7 0.31 11.4 0.3 3.0 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V YqzM PF14141.6 KEY69359.1 - 3.7 7.7 10.7 8.4 6.5 0.7 2.7 2 0 0 2 2 2 0 YqzM-like protein FAD_binding_3 PF01494.19 KEY69360.1 - 5e-22 78.6 0.0 5.8e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY69360.1 - 9.9e-05 22.5 0.1 0.00023 21.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY69360.1 - 0.00055 19.2 0.1 0.00088 18.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEY69360.1 - 0.0026 17.1 0.1 0.0053 16.0 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEY69360.1 - 0.0035 16.4 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KEY69360.1 - 0.015 15.9 0.2 0.051 14.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY69360.1 - 0.019 14.5 0.3 0.05 13.2 0.2 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY69360.1 - 0.039 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY69360.1 - 0.18 10.8 0.0 2.3 7.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.18 KEY69361.1 - 8.2e-10 38.2 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69361.1 - 5.1e-08 32.9 10.8 1e-07 31.9 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4606 PF15379.6 KEY69361.1 - 0.87 9.9 3.5 1.2 9.4 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) DUF2039 PF10217.9 KEY69361.1 - 2.1 8.8 8.3 4.7 7.6 8.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) TPR_12 PF13424.6 KEY69362.1 - 3.1e-39 133.1 7.2 3.9e-10 39.9 0.1 5.9 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEY69362.1 - 5.1e-30 102.5 4.8 2.2e-06 27.3 0.0 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEY69362.1 - 1.5e-07 31.0 7.3 0.0004 20.2 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY69362.1 - 1.1e-06 28.3 4.2 0.014 15.4 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY69362.1 - 6.9e-06 25.9 0.1 4.2 7.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY69362.1 - 8.7e-06 25.3 4.3 1.7e-05 24.4 3.9 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 KEY69362.1 - 2.9e-05 24.3 2.7 8.4 7.3 0.4 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY69362.1 - 0.00028 21.3 1.7 2.2 8.9 0.0 5.5 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY69362.1 - 0.00028 20.6 0.3 0.07 13.0 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY69362.1 - 0.00037 20.6 0.3 5.4 7.2 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Arylesterase PF01731.20 KEY69362.1 - 0.0011 19.1 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 Arylesterase AAA_22 PF13401.6 KEY69362.1 - 0.0019 18.5 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 KEY69362.1 - 0.0024 18.6 2.7 17 6.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NB-ARC PF00931.22 KEY69362.1 - 0.0055 15.9 0.0 0.12 11.5 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain DUF4807 PF16065.5 KEY69362.1 - 0.036 13.7 0.1 9.5 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) Peptidase_M14 PF00246.24 KEY69363.1 - 5.9e-41 141.2 0.0 7.9e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Asparaginase_II PF06089.12 KEY69364.1 - 7.4e-117 390.0 0.0 8.4e-117 389.8 0.0 1.0 1 0 0 1 1 1 1 L-asparaginase II Lipase_GDSL_2 PF13472.6 KEY69365.1 - 3.8e-17 63.3 0.7 5.2e-17 62.8 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY69365.1 - 6.9e-07 29.4 0.8 1.3e-06 28.5 0.8 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1349 PF07081.11 KEY69366.1 - 6.1e-24 84.7 0.1 9.6e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GMC_oxred_N PF00732.19 KEY69367.1 - 2.2e-54 184.8 0.0 3.3e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY69367.1 - 7.1e-32 110.9 0.0 3.8e-31 108.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY69367.1 - 0.00047 20.3 0.1 0.0014 18.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY69367.1 - 0.00081 18.7 0.2 0.14 11.3 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY69367.1 - 0.0011 18.2 0.1 0.036 13.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEY69367.1 - 0.0028 17.3 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY69367.1 - 0.0052 16.1 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY69367.1 - 0.019 13.7 0.0 0.044 12.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KEY69367.1 - 0.092 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KEY69367.1 - 0.13 12.9 0.2 0.29 11.7 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY69367.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_7 PF00840.20 KEY69368.1 - 1.5e-107 360.0 12.2 2.2e-90 303.5 13.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 NmrA PF05368.13 KEY69370.1 - 4.1e-05 23.3 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY69370.1 - 0.0034 17.3 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding zf-3CxxC PF13695.6 KEY69371.1 - 2.9e-22 79.0 0.7 2.9e-22 79.0 0.7 1.5 2 0 0 2 2 2 1 Zinc-binding domain PCAF_N PF06466.11 KEY69371.1 - 0.0067 16.0 0.4 0.0095 15.5 0.4 1.2 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain zf-3CxxC_2 PF17180.4 KEY69371.1 - 1.1 10.1 8.2 11 6.8 3.8 3.1 2 1 0 2 2 2 0 Zinc-binding domain Methyltransf_31 PF13847.6 KEY69372.1 - 3.1e-25 88.7 0.0 8e-25 87.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69372.1 - 3.2e-23 82.2 0.0 1.1e-22 80.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69372.1 - 4.9e-23 81.6 0.0 2.1e-22 79.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69372.1 - 3.7e-16 59.4 0.0 6.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY69372.1 - 1.7e-15 57.5 0.0 3.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY69372.1 - 1.5e-14 53.9 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KEY69372.1 - 1.1e-09 38.3 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEY69372.1 - 2e-07 30.7 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEY69372.1 - 4.1e-05 23.1 0.0 9.5e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KEY69372.1 - 0.00043 19.9 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KEY69372.1 - 0.00091 19.1 0.0 0.0043 16.9 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 KEY69372.1 - 0.0018 18.4 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.20 KEY69372.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 KEY69372.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.20 KEY69372.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 KEY69376.1 - 3.1e-31 108.6 32.3 3.1e-31 108.6 32.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Kinocilin PF15033.6 KEY69376.1 - 0.18 11.4 1.3 0.74 9.5 0.1 2.5 2 0 0 2 2 2 0 Kinocilin protein Cutinase PF01083.22 KEY69378.1 - 2.3e-28 99.4 0.0 3.4e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEY69378.1 - 0.0021 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 KEY69378.1 - 0.038 14.6 0.5 0.15 12.6 0.3 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.11 KEY69378.1 - 0.051 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SH3_7 PF12914.7 KEY69378.1 - 0.068 13.4 0.1 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of SH3b2 type DUF2974 PF11187.8 KEY69378.1 - 0.072 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 KEY69378.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 KEY69378.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Bac_rhamnosid_C PF17390.2 KEY69379.1 - 1.7e-09 37.3 0.1 4.7e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KEY69379.1 - 1.4e-07 31.1 0.0 1.1e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid PF05592.11 KEY69379.1 - 0.022 14.7 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain UDPGT PF00201.18 KEY69380.1 - 6.3e-14 51.6 0.0 9.3e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KEY69380.1 - 0.0026 17.8 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Fructosamin_kin PF03881.14 KEY69381.1 - 6.1e-37 127.4 0.0 8.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEY69381.1 - 0.00094 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Inv-AAD PF18785.1 KEY69382.1 - 1.3e-56 189.9 0.0 1.6e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KEY69382.1 - 1e-15 57.5 0.1 1.3e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KEY69382.1 - 0.00014 21.8 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 KEY69382.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 0 MafB19-like deaminase NAD1 PF18778.1 KEY69382.1 - 0.095 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 ANAPC4_WD40 PF12894.7 KEY69383.1 - 7.7e-08 32.5 0.0 0.82 10.0 0.0 5.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY69383.1 - 1.7e-06 28.1 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KEY69383.1 - 2.5e-05 23.9 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.32 KEY69383.1 - 0.00027 21.7 0.0 4 8.5 0.0 5.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PGAP1 PF07819.13 KEY69383.1 - 0.00052 19.8 0.1 0.0016 18.2 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEY69383.1 - 0.0028 18.3 0.1 0.012 16.2 0.0 2.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family WD40_like PF17005.5 KEY69383.1 - 0.029 13.7 0.0 9.6 5.4 0.0 3.3 3 1 0 3 3 3 0 WD40-like domain AAA_16 PF13191.6 KEY69383.1 - 0.088 13.2 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 KEY69383.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_pol_L_2 PF13656.6 KEY69384.1 - 2.9e-31 107.0 0.0 4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEY69384.1 - 6.9e-12 44.6 0.0 9.4e-12 44.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_60s PF00428.19 KEY69384.1 - 1 10.0 12.4 2.2 8.9 12.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Complex1_LYR_2 PF13233.6 KEY69385.1 - 1e-06 29.4 0.1 1.4e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KEY69385.1 - 3.1e-05 23.9 0.2 6.7e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) G10 PF01125.17 KEY69386.1 - 2.6e-62 208.9 3.6 2.9e-62 208.8 3.6 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2 PF00096.26 KEY69387.1 - 0.059 13.8 0.7 0.059 13.8 0.7 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KEY69387.1 - 0.13 12.6 1.1 0.55 10.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KEY69387.1 - 8.2 7.6 12.0 0.64 11.0 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 KEY69388.1 - 3.7e-50 171.0 0.2 7e-50 170.1 0.2 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KEY69388.1 - 1.9e-24 86.8 0.3 6.4e-24 85.1 0.3 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.24 KEY69389.1 - 1.8e-67 227.8 0.0 2.1e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L2_C PF03947.18 KEY69390.1 - 4.3e-42 143.3 4.4 6.3e-42 142.8 4.4 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEY69390.1 - 0.0029 17.5 0.4 0.14 12.1 0.4 2.7 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 KEY69391.1 - 4.3e-05 23.0 0.0 9.6e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 COPI_C PF06957.11 KEY69391.1 - 2.3 6.9 6.3 3.7 6.2 6.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 KEY69391.1 - 5.2 6.3 9.3 11 5.2 9.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1770 PF08589.10 KEY69392.1 - 3.3e-38 130.7 1.4 3.9e-38 130.4 1.4 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.15 KEY69393.1 - 1e-47 161.8 0.1 1.8e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KEY69393.1 - 6.2e-41 139.4 0.5 1.3e-40 138.4 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KEY69393.1 - 1.6e-21 76.6 0.0 2.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KEY69393.1 - 5.2e-11 42.9 0.5 2e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KEY69393.1 - 2.3e-09 37.6 0.0 3.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor GMP_PDE_delta PF05351.11 KEY69393.1 - 0.027 14.5 0.8 0.07 13.2 0.5 1.8 2 0 0 2 2 2 0 GMP-PDE, delta subunit DUF3440 PF11922.8 KEY69393.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) VASt PF16016.5 KEY69394.1 - 4.9e-36 124.5 1.5 1.9e-35 122.5 0.7 2.3 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KEY69394.1 - 3.7e-18 66.1 0.0 6.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 KEY69394.1 - 2e-06 27.6 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 BAR domain PH PF00169.29 KEY69394.1 - 0.00029 21.3 0.1 0.0011 19.5 0.1 2.0 1 1 0 1 1 1 1 PH domain GRAM PF02893.20 KEY69394.1 - 0.025 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DUF3074 PF11274.8 KEY69395.1 - 8.8e-55 185.5 1.2 7.3e-53 179.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) LMBR1 PF04791.16 KEY69395.1 - 2.9 6.7 8.8 4.1 6.2 8.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2428 PF10350.9 KEY69396.1 - 2.3e-59 200.9 0.1 6.4e-59 199.5 0.1 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KEY69396.1 - 6.5e-11 41.5 9.1 0.082 13.2 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KEY69396.1 - 1.1e-06 28.9 8.1 0.041 14.3 0.2 5.9 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KEY69396.1 - 0.00067 20.1 8.3 0.035 14.6 0.3 5.4 5 0 0 5 5 5 1 HEAT-like repeat Proteasom_PSMB PF10508.9 KEY69396.1 - 0.011 14.2 0.9 0.58 8.6 0.0 3.5 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit IL13 PF03487.13 KEY69396.1 - 0.059 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Interleukin-13 Ribosomal_L1 PF00687.21 KEY69397.1 - 3.6e-44 151.0 0.1 4.3e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.21 KEY69398.1 - 1e-57 194.4 0.2 6.5e-56 188.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KEY69398.1 - 1.6e-09 38.0 0.1 2.4e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KEY69398.1 - 2e-07 30.5 0.0 3.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 KEY69398.1 - 4.2e-06 26.4 0.0 6.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEY69398.1 - 8.6e-06 25.3 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEY69398.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KEY69398.1 - 0.0061 15.6 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_C PF00137.21 KEY69399.1 - 2.7e-29 101.3 28.1 3.5e-20 72.1 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KEY69399.1 - 0.021 14.5 0.9 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Pep3_Vps18 PF05131.14 KEY69400.1 - 3e-44 150.4 0.2 7.4e-44 149.2 0.2 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KEY69400.1 - 3.4e-10 40.0 6.2 4e-07 30.0 0.1 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 KEY69400.1 - 2.5e-07 30.9 0.3 0.00066 19.9 0.0 3.0 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.6 KEY69400.1 - 0.00026 20.8 0.4 0.00061 19.6 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY69400.1 - 0.0011 18.8 0.3 0.0011 18.8 0.3 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KEY69400.1 - 0.0018 17.9 0.1 0.0036 16.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KEY69400.1 - 0.0028 17.9 0.5 0.008 16.5 0.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEY69400.1 - 0.0096 15.9 0.5 0.027 14.5 0.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_2 PF10367.9 KEY69400.1 - 0.045 14.2 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 KEY69400.1 - 0.13 12.6 0.2 0.37 11.1 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KEY69400.1 - 0.39 10.8 7.3 0.041 13.9 2.0 2.1 3 0 0 3 3 3 0 Zinc-finger zf-C3HC4 PF00097.25 KEY69400.1 - 1.6 8.7 4.1 0.34 10.8 0.2 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEY69400.1 - 2.3 8.0 12.4 0.049 13.4 4.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_23 PF13489.6 KEY69401.1 - 7.7e-15 55.1 0.0 2e-14 53.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69401.1 - 1.2e-09 38.2 0.0 2.9e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69401.1 - 3.5e-09 37.2 0.0 9.6e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY69401.1 - 2.4e-08 34.6 0.0 7.2e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69401.1 - 1.4e-05 25.6 0.0 4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEY69401.1 - 0.00011 21.6 0.0 0.00067 19.0 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KEY69401.1 - 0.008 15.7 0.3 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.12 KEY69401.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 KEY69401.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KEY69401.1 - 0.059 12.7 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEY69401.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 KEY69402.1 - 1.5e-68 231.6 0.0 1.8e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEY69402.1 - 7.3e-56 189.3 0.0 9.1e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY69402.1 - 1.1e-21 77.3 0.0 1e-20 74.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEY69402.1 - 8e-21 74.3 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY69402.1 - 1.2e-18 67.2 0.1 3.6e-17 62.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KEY69402.1 - 6e-18 64.9 0.0 7.7e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEY69402.1 - 2.8e-07 30.6 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEY69402.1 - 0.056 12.9 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Brix PF04427.18 KEY69403.1 - 1.6e-24 87.1 0.0 2.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain GPCR_chapero_1 PF11904.8 KEY69403.1 - 2.7 7.3 8.5 0.19 11.2 0.6 2.1 2 0 0 2 2 2 0 GPCR-chaperone NOC3p PF07540.11 KEY69404.1 - 3.9e-29 100.9 0.1 3.6e-27 94.6 0.0 3.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KEY69404.1 - 2.6e-26 92.7 1.7 4.1e-26 92.0 0.1 2.1 2 1 0 2 2 2 1 CBF/Mak21 family CCDC53 PF10152.9 KEY69404.1 - 0.29 11.5 3.5 0.98 9.8 0.1 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RNase_P_pop3 PF08228.11 KEY69405.1 - 5.1e-10 39.6 0.0 7.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 GARS_A PF01071.19 KEY69406.1 - 4.4e-82 274.6 0.0 8.9e-82 273.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KEY69406.1 - 1e-35 122.3 0.1 1e-34 119.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KEY69406.1 - 2.4e-34 118.7 0.1 5.4e-34 117.6 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KEY69406.1 - 6.5e-26 90.4 2.2 1.1e-25 89.7 0.7 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KEY69406.1 - 9.3e-15 55.1 3.3 3.8e-14 53.1 3.2 2.2 1 1 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KEY69406.1 - 0.00028 20.5 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KEY69406.1 - 0.00053 19.5 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 KEY69406.1 - 0.0038 16.8 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KEY69406.1 - 0.0048 16.5 0.3 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KEY69406.1 - 0.018 14.5 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 KEY69406.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 KEY69406.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain DUF3517 PF12030.8 KEY69407.1 - 1.9e-91 306.5 0.0 9.1e-91 304.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 KEY69407.1 - 9.3e-43 146.6 0.1 1.7e-42 145.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY69407.1 - 5.7e-19 68.9 0.0 1.1e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPAP1_C PF08620.10 KEY69407.1 - 0.15 12.1 0.1 0.45 10.7 0.1 1.8 1 0 0 1 1 1 0 RPAP1-like, C-terminal RNA_pol_3_Rpc31 PF11705.8 KEY69407.1 - 0.16 12.2 15.8 0.083 13.1 8.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KEY69407.1 - 0.46 10.2 25.7 0.23 11.2 11.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PRCC PF10253.9 KEY69409.1 - 1.8e-31 110.6 19.5 4.4e-30 106.1 19.5 2.7 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting CRIM PF16978.5 KEY69410.1 - 1.6e-45 154.7 0.0 3.3e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KEY69410.1 - 1.8e-30 105.4 0.0 3.6e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KEY69410.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KEY69410.1 - 0.095 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain PBP1_TM PF14812.6 KEY69410.1 - 0.65 10.4 7.3 0.88 10.0 2.4 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2884 PF11101.8 KEY69411.1 - 0.011 15.3 0.3 1.4 8.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) Baculo_PEP_C PF04513.12 KEY69411.1 - 0.047 13.7 0.0 2.6 8.1 0.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CwsA PF10814.8 KEY69411.1 - 0.066 13.4 1.9 0.1 12.7 1.9 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Apolipoprotein PF01442.18 KEY69411.1 - 0.081 12.8 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3852 PF12963.7 KEY69411.1 - 0.2 12.0 4.5 8 6.9 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3852) SNARE PF05739.19 KEY69411.1 - 0.22 11.5 0.4 0.93 9.5 0.0 2.1 3 0 0 3 3 3 0 SNARE domain Tape_meas_lam_C PF09718.10 KEY69411.1 - 0.43 10.8 5.9 2.3 8.4 0.3 3.5 1 1 3 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PMEI PF04043.15 KEY69411.1 - 0.62 10.4 4.2 2.2 8.6 0.1 2.9 1 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Zip PF02535.22 KEY69413.1 - 1.6e-33 116.3 22.7 2.5e-25 89.4 9.7 3.1 2 1 0 3 3 3 3 ZIP Zinc transporter WD40 PF00400.32 KEY69414.1 - 3.9e-38 128.8 24.2 8.5e-08 32.8 0.4 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KEY69414.1 - 1.2e-12 47.5 0.6 2.5e-12 46.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KEY69414.1 - 8.6e-10 38.8 1.5 0.18 12.1 0.0 5.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY69414.1 - 1.2e-07 30.8 6.0 0.028 13.1 0.1 5.6 1 1 5 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 KEY69414.1 - 4.5e-06 26.4 2.1 9.4e-06 25.4 2.1 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KEY69414.1 - 0.0013 18.1 0.0 0.11 11.8 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 KEY69414.1 - 0.0071 16.4 0.0 3 7.9 0.0 3.4 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 KEY69414.1 - 0.018 14.7 3.4 0.18 11.3 1.0 3.2 1 1 1 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KEY69414.1 - 0.02 13.8 2.6 18 4.2 0.0 3.8 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain F-box_5 PF18511.1 KEY69414.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 F-box EH_Signature PF15611.6 KEY69414.1 - 0.18 11.2 0.0 9.1 5.6 0.0 2.1 2 0 0 2 2 2 0 EH_Signature domain E1_dh PF00676.20 KEY69415.1 - 1e-113 379.3 0.2 1.2e-113 379.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEY69415.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 KEY69416.1 - 1.5e-60 204.4 1.0 4.8e-48 163.5 0.5 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEY69416.1 - 2.4e-42 145.2 0.0 5e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KEY69416.1 - 6.9e-29 100.4 0.0 2.4e-28 98.6 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KEY69416.1 - 2.4e-05 24.7 0.2 3.9e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 RNA ligase PNKP_ligase PF16542.5 KEY69416.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Voltage_CLC PF00654.20 KEY69417.1 - 6.5e-88 295.3 27.4 9.8e-88 294.8 27.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KEY69417.1 - 0.00042 20.7 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 1 CBS domain LacI PF00356.21 KEY69417.1 - 0.63 9.9 1.9 1.9 8.4 1.9 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Neurochondrin PF05536.11 KEY69418.1 - 1.3e-88 297.9 1.5 3.4e-88 296.6 1.4 1.6 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 KEY69418.1 - 0.00036 20.3 4.3 0.23 11.2 0.0 3.6 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 KEY69418.1 - 0.066 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Rhabdo_ncap PF00945.18 KEY69419.1 - 0.0027 16.7 0.1 0.017 14.0 0.0 1.9 2 0 0 2 2 2 1 Rhabdovirus nucleocapsid protein MFS_1 PF07690.16 KEY69420.1 - 1.7e-53 181.8 33.1 2.1e-47 161.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY69420.1 - 1e-14 54.0 12.8 1.6e-08 33.5 0.2 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 KEY69420.1 - 2e-10 40.1 11.5 2.1e-10 40.1 6.5 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KEY69420.1 - 3.7e-06 25.5 0.2 0.00042 18.7 0.0 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KEY69420.1 - 0.06 11.7 17.6 0.061 11.7 8.1 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 KEY69420.1 - 2.9 6.6 18.1 1.2 7.9 5.2 3.4 2 2 2 4 4 4 0 MFS_1 like family Ras PF00071.22 KEY69421.1 - 2.9e-52 176.5 0.0 3.4e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY69421.1 - 1.5e-18 67.2 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY69421.1 - 2.8e-06 26.9 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KEY69422.1 - 8.5e-89 297.8 0.0 1.1e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KEY69422.1 - 0.029 14.6 0.2 0.055 13.7 0.1 1.4 1 1 0 1 1 1 0 UPF0489 domain RRM_1 PF00076.22 KEY69423.1 - 8.6e-38 128.0 0.1 7.8e-12 44.8 0.1 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY69423.1 - 1.1e-16 60.4 0.0 0.0062 16.4 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KEY69423.1 - 7.9e-09 35.1 3.4 7.9e-09 35.1 3.4 3.6 4 0 0 4 4 4 1 Putative RRM domain DUF4523 PF15023.6 KEY69423.1 - 2e-05 24.5 0.0 0.11 12.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KEY69423.1 - 0.00037 20.5 0.0 3.5 7.8 0.0 4.1 5 0 0 5 5 5 1 RNA recognition motif RRM_3 PF08777.11 KEY69423.1 - 0.0044 17.0 0.1 0.23 11.5 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KEY69423.1 - 0.042 13.9 0.0 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KEY69423.1 - 0.053 13.3 0.0 0.96 9.2 0.0 3.0 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF3072 PF11272.8 KEY69423.1 - 0.083 12.8 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) RNA_bind PF08675.11 KEY69423.1 - 0.09 12.8 0.5 0.37 10.9 0.0 2.2 3 0 0 3 3 3 0 RNA binding domain His_Phos_2 PF00328.22 KEY69424.1 - 2.1e-16 60.3 0.0 3.9e-15 56.1 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Abhydrolase_6 PF12697.7 KEY69425.1 - 0.00097 19.8 3.0 0.0034 18.0 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 KEY69425.1 - 0.0048 16.1 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KEY69425.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KEY69425.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MIF PF01187.18 KEY69428.1 - 4e-11 43.2 0.0 6.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.12 KEY69429.1 - 2.2e-69 233.4 0.1 2.8e-69 233.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KEY69429.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEY69429.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEY69429.1 - 0.025 14.6 0.0 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY69429.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KEY69429.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ANAPC4 PF12896.7 KEY69430.1 - 4.8e-67 225.4 0.0 6.6e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KEY69430.1 - 1.4e-08 34.9 0.0 0.0003 21.0 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Adap_comp_sub PF00928.21 KEY69431.1 - 3.3e-18 66.0 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEY69431.1 - 3.5e-08 33.5 0.1 5.6e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KEY69431.1 - 0.0018 17.8 0.0 0.012 15.1 0.0 2.0 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 KEY69431.1 - 0.12 12.7 1.7 0.14 12.6 0.4 1.7 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 KEY69432.1 - 3.4e-09 36.7 0.4 5.1e-09 36.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 KEY69433.1 - 4.7e-103 344.4 12.6 5.6e-103 344.1 12.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KEY69433.1 - 3.9e-05 23.8 5.9 3.9e-05 23.8 5.9 3.5 3 1 0 3 3 3 1 EamA-like transporter family Transmemb_17 PF09799.9 KEY69433.1 - 3 8.5 11.5 4.5 7.9 3.9 2.6 2 1 0 2 2 2 0 Predicted membrane protein Ribosomal_S3_C PF00189.20 KEY69434.1 - 8.9e-25 87.0 0.2 4.5e-24 84.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KEY69434.1 - 5.7e-12 45.3 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 KEY69434.1 - 0.098 12.5 0.4 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 KEY69434.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.14 KEY69435.1 - 9.6e-150 498.4 0.1 1.2e-149 498.1 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain G-alpha PF00503.20 KEY69435.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DSPc PF00782.20 KEY69435.1 - 0.12 12.2 0.8 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KEY69435.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family tRNA_synthFbeta PF17759.1 KEY69436.1 - 6.2e-46 156.5 0.0 9.1e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KEY69436.1 - 4.8e-32 110.0 0.4 1.1e-30 105.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KEY69436.1 - 1.8e-27 96.2 0.0 3.7e-27 95.1 0.0 1.6 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.15 KEY69436.1 - 1.1e-16 60.8 0.0 8.1e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 KEY69437.1 - 9.5e-38 125.0 15.8 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 KEY69437.1 - 2.6e-33 114.2 4.5 9.5e-11 41.9 0.0 7.9 4 2 3 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 KEY69437.1 - 3.5e-13 49.7 5.1 0.033 14.7 0.0 8.2 8 2 2 10 10 9 3 HEAT-like repeat Cnd1 PF12717.7 KEY69437.1 - 2.8e-11 43.7 11.2 0.00063 19.8 0.2 5.9 5 1 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEY69437.1 - 5.8e-11 42.8 5.0 0.02 15.5 0.1 7.4 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KEY69437.1 - 1.2e-07 30.7 9.2 0.0028 16.3 0.2 4.8 3 2 2 6 6 6 4 Adaptin N terminal region RTP1_C1 PF10363.9 KEY69437.1 - 1.4e-07 31.7 7.2 0.067 13.4 0.1 5.3 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KEY69437.1 - 8.7e-06 25.5 3.3 1.5 8.3 0.0 4.8 3 3 1 4 4 4 3 CLASP N terminal Proteasom_PSMB PF10508.9 KEY69437.1 - 0.017 13.7 4.2 0.42 9.1 0.0 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 KEY69437.1 - 0.021 15.1 0.3 11 6.3 0.0 3.3 2 1 0 3 3 3 0 Apoptosis regulator M11L like Arm PF00514.23 KEY69437.1 - 0.1 12.7 4.7 3.1 8.0 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 KEY69437.1 - 0.19 10.4 3.7 5.4 5.6 0.0 3.8 4 1 1 5 5 5 0 Proteasome stabiliser Methyltransf_31 PF13847.6 KEY69438.1 - 2.8e-09 36.9 0.0 6.2e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69438.1 - 3.4e-07 30.9 0.0 7.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY69438.1 - 7.1e-07 29.9 0.0 6e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69438.1 - 1e-06 28.7 0.0 6.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69438.1 - 1.2e-05 25.8 0.0 2.4e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY69438.1 - 0.00057 19.5 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.13 KEY69438.1 - 0.0028 17.9 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KEY69438.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KEY69438.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain eIF-6 PF01912.18 KEY69439.1 - 1.2e-80 269.5 0.9 1.8e-80 269.0 0.9 1.2 1 0 0 1 1 1 1 eIF-6 family Tim54 PF11711.8 KEY69440.1 - 1.3 7.8 12.9 5.1 5.8 12.9 2.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_C65 PF10275.9 KEY69441.1 - 2.9e-62 210.3 0.0 3.9e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Ferric_reduct PF01794.19 KEY69442.1 - 1.5e-19 70.3 15.4 1.5e-19 70.3 15.4 2.8 4 0 0 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY69442.1 - 7e-05 23.0 0.0 0.26 11.4 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY69442.1 - 0.00029 20.9 0.1 0.066 13.3 0.1 2.8 3 0 0 3 3 3 1 FAD-binding domain MHYT PF03707.16 KEY69442.1 - 0.0056 16.8 2.6 0.007 16.5 0.2 2.5 2 0 0 2 2 2 1 Bacterial signalling protein N terminal repeat NAD_binding_1 PF00175.21 KEY69442.1 - 0.081 13.6 0.0 0.23 12.1 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4293 PF14126.6 KEY69442.1 - 2.4 8.4 14.6 2.6 8.3 2.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) DUF4405 PF14358.6 KEY69442.1 - 2.5 8.7 13.5 1 10.0 4.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Guanylate_kin PF00625.21 KEY69443.1 - 5.3e-60 202.2 0.0 6.3e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KEY69443.1 - 5.6e-05 23.7 0.0 9.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEY69443.1 - 0.00025 21.2 0.0 0.0034 17.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY69443.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY69443.1 - 0.0043 17.5 0.1 0.0055 17.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEY69443.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase dNK PF01712.19 KEY69443.1 - 0.0087 15.9 0.1 0.12 12.2 0.1 2.3 1 1 0 1 1 1 1 Deoxynucleoside kinase MMR_HSR1 PF01926.23 KEY69443.1 - 0.0096 16.0 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEY69443.1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KEY69443.1 - 0.02 15.2 0.1 0.066 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEY69443.1 - 0.04 13.8 0.1 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KEY69443.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.6 KEY69443.1 - 0.069 13.9 0.0 3.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain AAA_24 PF13479.6 KEY69443.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEY69443.1 - 0.086 12.3 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KEY69443.1 - 0.096 13.1 0.2 0.41 11.1 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KEY69443.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 KEY69443.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Rad17 P-loop domain DUF5417 PF17438.2 KEY69443.1 - 0.12 12.7 0.0 4.2 7.7 0.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5417) AAA_29 PF13555.6 KEY69443.1 - 0.23 11.2 0.2 0.51 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sulfate_transp PF00916.20 KEY69444.1 - 1.1e-106 356.8 20.1 1.4e-106 356.5 20.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEY69444.1 - 5.7e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KEY69444.1 - 0.0002 21.7 19.2 0.0011 19.3 4.4 2.9 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KEY69444.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 STAS domain YjcZ PF13990.6 KEY69445.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 YjcZ-like protein adh_short PF00106.25 KEY69446.1 - 2.4e-35 121.8 0.0 3.3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69446.1 - 2.7e-24 86.0 0.0 3.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LysM PF01476.20 KEY69447.1 - 5.3e-11 42.4 0.0 8.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Actino_peptide PF14408.6 KEY69447.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes HEAT_EZ PF13513.6 KEY69448.1 - 3.6e-19 68.9 8.8 3.9e-09 36.8 0.1 8.2 7 1 2 9 9 8 4 HEAT-like repeat HEAT PF02985.22 KEY69448.1 - 6.8e-13 47.7 10.1 0.0025 17.9 0.1 9.0 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 KEY69448.1 - 8.5e-13 48.5 10.8 0.0076 16.6 0.0 7.6 4 2 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KEY69448.1 - 3.3e-07 30.8 0.0 0.43 11.2 0.0 5.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KEY69448.1 - 7.4e-07 28.6 5.5 0.014 14.5 1.0 4.2 1 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KEY69448.1 - 2e-06 26.7 0.9 0.064 11.8 0.0 4.5 3 1 1 5 5 5 2 Adaptin N terminal region RIX1 PF08167.12 KEY69448.1 - 4.1e-06 26.7 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KEY69448.1 - 6.6e-05 23.0 1.3 0.36 10.9 0.1 4.7 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KEY69448.1 - 7.3e-05 22.6 0.2 0.00061 19.7 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KEY69448.1 - 7.5e-05 22.6 0.2 0.51 10.5 0.0 4.2 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat UME PF08064.13 KEY69448.1 - 0.0001 22.1 0.5 0.38 10.7 0.0 4.5 5 0 0 5 5 5 1 UME (NUC010) domain ParcG PF10274.9 KEY69448.1 - 0.00021 21.5 0.1 0.28 11.3 0.1 3.5 3 1 1 4 4 4 1 Parkin co-regulated protein CLASP_N PF12348.8 KEY69448.1 - 0.00044 19.9 0.0 0.83 9.2 0.0 4.1 4 1 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 KEY69448.1 - 0.0089 15.2 0.2 6 5.9 0.2 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal V-ATPase_H_N PF03224.14 KEY69448.1 - 0.013 14.8 0.5 16 4.7 0.2 3.7 1 1 1 3 3 3 0 V-ATPase subunit H RTP1_C1 PF10363.9 KEY69448.1 - 0.046 13.9 1.6 3.2 8.0 0.1 3.9 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KEY69448.1 - 0.058 13.3 3.0 6.8 6.6 0.1 4.9 4 2 0 4 4 4 0 Domain of unknown function (DUF3385) Pollen_allerg_2 PF01620.16 KEY69448.1 - 0.12 12.6 0.2 0.96 9.6 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) DUF747 PF05346.11 KEY69449.1 - 4.8e-118 394.3 5.2 6.3e-118 393.9 5.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family HemY_N PF07219.13 KEY69449.1 - 1.3 9.3 3.1 3.5 7.9 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus DLH PF01738.18 KEY69450.1 - 3.9e-24 85.4 0.0 5e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KEY69450.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-U1 PF06220.12 KEY69451.1 - 4.9e-07 29.4 2.0 7.6e-07 28.8 2.0 1.3 1 0 0 1 1 1 1 U1 zinc finger PIR PF00399.19 KEY69452.1 - 3e-35 119.0 80.3 2.7e-06 26.8 2.4 9.5 9 0 0 9 9 9 8 Yeast PIR protein repeat Peptidase_M36 PF02128.15 KEY69453.1 - 4.3e-153 509.9 0.2 5.4e-153 509.5 0.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KEY69453.1 - 7.4e-19 67.3 3.2 1.2e-18 66.7 1.8 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif DUF4901 PF16244.5 KEY69453.1 - 0.047 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) Gpi16 PF04113.14 KEY69454.1 - 2.5e-240 798.7 0.0 2.9e-240 798.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KEY69455.1 - 6e-72 242.3 0.5 7.3e-72 242.0 0.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1241 PF06840.11 KEY69455.1 - 0.0073 16.0 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) MCPsignal PF00015.21 KEY69455.1 - 0.05 13.4 0.1 0.091 12.6 0.1 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Imm49 PF15575.6 KEY69455.1 - 0.058 13.1 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 49 CDC27 PF09507.10 KEY69456.1 - 0.00022 20.7 20.6 0.00022 20.7 20.6 1.5 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 TFIIA PF03153.13 KEY69456.1 - 0.043 13.8 9.7 0.066 13.2 9.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.8 KEY69456.1 - 0.74 9.5 26.2 1.3 8.7 26.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nuc_deoxyri_tr2 PF15891.5 KEY69457.1 - 3.1e-39 133.6 0.0 3.9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 KEY69457.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Sortilin-Vps10 PF15902.5 KEY69459.1 - 1.5e-13 50.4 1.5 0.00046 19.1 0.0 4.9 4 2 1 5 5 5 3 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KEY69459.1 - 9.5e-12 44.7 13.7 9.5e-12 44.7 13.7 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR PF02012.20 KEY69459.1 - 2.4e-06 26.7 28.9 0.18 11.9 0.1 9.4 10 0 0 10 10 10 4 BNR/Asp-box repeat Toxin_7 PF05980.12 KEY69459.1 - 0.011 15.9 2.3 0.019 15.2 2.3 1.4 1 0 0 1 1 1 0 Toxin 7 BNR_6 PF15899.5 KEY69459.1 - 0.022 14.8 8.3 8.9 6.7 0.0 6.1 7 0 0 7 7 7 0 BNR-Asp box repeat Sacchrp_dh_C PF16653.5 KEY69460.1 - 3.1e-30 106.2 0.0 5.5e-18 66.0 0.0 2.1 1 1 1 2 2 2 2 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KEY69460.1 - 3e-12 46.9 0.1 1.8e-10 41.2 0.0 2.1 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEY69460.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KEY69460.1 - 2.3e-05 24.5 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KEY69460.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KEY69460.1 - 0.051 14.0 0.0 0.098 13.1 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 KEY69460.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEY69460.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family XdhC_C PF13478.6 KEY69460.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Sugar_tr PF00083.24 KEY69461.1 - 5.8e-85 285.8 24.7 6.8e-85 285.6 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69461.1 - 2.6e-43 148.3 56.3 1.6e-35 122.6 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY69461.1 - 0.34 9.3 15.3 0.006 15.1 2.5 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.17 KEY69463.1 - 7.5e-100 333.9 0.2 1.4e-99 333.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KEY69463.1 - 3.9e-62 210.0 0.1 6.5e-62 209.3 0.1 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KEY69463.1 - 8.9e-39 133.1 0.1 1.8e-38 132.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KEY69463.1 - 1.4e-23 83.2 0.0 3.4e-22 78.7 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KEY69463.1 - 1.8e-11 44.7 0.0 6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KEY69463.1 - 0.0038 17.8 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Peptidase_M20 PF01546.28 KEY69464.1 - 1.2e-22 80.6 0.0 6.9e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KEY69464.1 - 7.3e-15 55.1 8.7 0.018 15.9 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Peptidase_M28 PF04389.17 KEY69464.1 - 0.00029 20.6 0.0 0.00086 19.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KEY69464.1 - 0.00061 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KEY69464.1 - 0.002 18.4 0.0 2.7 8.3 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M42 PF05343.14 KEY69464.1 - 0.035 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pec_lyase_C PF00544.19 KEY69465.1 - 7.6e-41 140.0 5.7 9.9e-41 139.6 5.7 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY69465.1 - 0.14 12.0 5.0 1.3 8.9 5.0 2.2 1 1 0 1 1 1 0 Right handed beta helix region Herpes_DNAp_acc PF04929.12 KEY69467.1 - 0.22 10.4 2.0 0.24 10.4 2.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Methyltransf_2 PF00891.18 KEY69468.1 - 5.8e-19 68.2 0.0 9.5e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KEY69468.1 - 0.051 14.3 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KEY69470.1 - 4.1e-09 36.4 7.7 6.5e-09 35.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY69470.1 - 5.2e-07 28.8 0.1 8.1e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hira PF07569.11 KEY69471.1 - 8e-85 284.1 0.0 1.7e-84 283.0 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KEY69471.1 - 2.1e-34 117.0 22.4 2.3e-05 25.0 0.0 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69471.1 - 4e-18 65.5 0.1 0.012 15.9 0.0 6.5 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KEY69471.1 - 1e-09 38.0 0.4 1e-09 38.0 0.4 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KEY69471.1 - 9e-06 25.5 0.2 15 5.7 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEY69471.1 - 0.0016 17.4 1.2 0.25 10.2 0.0 3.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Herpes_LMP2 PF07415.11 KEY69471.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein IKI3 PF04762.12 KEY69471.1 - 0.13 10.2 0.2 0.59 8.0 0.0 2.0 3 0 0 3 3 3 0 IKI3 family RR_TM4-6 PF06459.12 KEY69471.1 - 0.14 12.0 3.5 0.22 11.3 3.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 KEY69472.1 - 1.7e-40 136.2 18.1 2.8e-05 24.8 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KEY69472.1 - 2.1e-10 40.3 0.1 4.7e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY69472.1 - 1.2e-09 37.8 0.0 3.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KEY69472.1 - 9.8e-07 29.0 0.9 1.2 9.5 0.0 5.6 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEY69472.1 - 0.01 15.5 2.0 5 6.6 0.6 2.9 2 1 0 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KEY69472.1 - 0.027 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 KEY69472.1 - 2.6 6.6 7.1 24 3.4 0.1 4.3 2 2 3 5 5 5 0 Nucleoporin Nup120/160 Mucin PF01456.17 KEY69473.1 - 1.5e-05 25.0 13.2 1.5e-05 25.0 13.2 2.4 2 0 0 2 2 2 1 Mucin-like glycoprotein PAN_4 PF14295.6 KEY69473.1 - 0.006 16.5 1.7 0.011 15.6 1.7 1.4 1 0 0 1 1 1 1 PAN domain AAA_11 PF13086.6 KEY69473.1 - 1.2 8.8 11.0 2.3 7.9 11.0 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_S28 PF05577.12 KEY69476.1 - 2.1e-45 155.3 0.0 2.1e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF2920 PF11144.8 KEY69476.1 - 0.018 14.2 0.2 0.028 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF1242 PF06842.12 KEY69477.1 - 6.2e-16 57.9 0.1 8.1e-16 57.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Glyco_hydro_61 PF03443.14 KEY69478.1 - 4.5e-66 222.7 0.0 7.2e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med3 PF11593.8 KEY69478.1 - 9.8 5.2 31.5 36 3.4 31.5 1.7 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Aminopep PF10023.9 KEY69479.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative aminopeptidase 2-Hacid_dh_C PF02826.19 KEY69480.1 - 2.7e-38 131.1 0.0 8.1e-26 90.5 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY69480.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HET PF06985.11 KEY69481.1 - 4.2e-33 114.8 0.0 7.1e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Asparaginase_2 PF01112.18 KEY69482.1 - 3.1e-68 230.1 7.5 4.1e-68 229.7 7.5 1.0 1 0 0 1 1 1 1 Asparaginase Dicty_REP PF05086.12 KEY69483.1 - 0.11 10.4 6.0 0.18 9.8 6.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ANAPC4_WD40 PF12894.7 KEY69484.1 - 4.1e-05 23.8 0.0 1.1 9.6 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY69484.1 - 0.00042 21.1 1.5 4.5 8.3 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEY69484.1 - 0.011 14.7 0.3 27 3.6 0.1 3.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY69484.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain RasGAP PF00616.19 KEY69485.1 - 3.8e-30 105.2 0.0 6.3e-21 75.0 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KEY69485.1 - 0.0024 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.22 KEY69485.1 - 0.2 12.0 0.9 38 4.9 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat XRN_M PF17846.1 KEY69486.1 - 3.4e-137 458.0 0.0 8.9e-137 456.6 0.0 1.7 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KEY69486.1 - 4.5e-99 330.8 0.0 6.7e-99 330.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 KEY69486.1 - 0.24 11.3 2.3 0.63 9.9 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 KEY69487.1 - 2.8e-112 374.9 0.0 5.4e-112 374.0 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KEY69487.1 - 9.7e-22 77.7 30.8 9.7e-22 77.7 30.8 5.2 2 1 3 5 5 5 2 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_25 PF13649.6 KEY69487.1 - 2.5e-10 40.9 0.0 1.4e-09 38.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEY69487.1 - 1e-09 38.2 0.2 1e-09 38.2 0.2 2.4 2 1 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KEY69487.1 - 5.2e-09 36.6 0.0 3.6e-08 33.9 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69487.1 - 2.1e-07 30.9 0.7 5.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69487.1 - 1.6e-05 24.8 0.0 6.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KEY69487.1 - 6e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY69487.1 - 0.00013 21.5 3.0 0.00017 21.2 0.2 2.4 3 0 0 3 3 3 1 Methyltransferase small domain ERM PF00769.19 KEY69487.1 - 0.00057 19.8 24.0 0.00057 19.8 24.0 2.8 1 1 1 2 2 1 1 Ezrin/radixin/moesin family Methyltransf_12 PF08242.12 KEY69487.1 - 0.0051 17.5 0.0 0.025 15.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY69487.1 - 0.0077 16.0 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KEY69487.1 - 0.039 12.9 0.0 0.039 12.9 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KEY69487.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 KEY69487.1 - 0.046 13.5 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 KEY69487.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Filament PF00038.21 KEY69487.1 - 1.8 8.0 62.2 3.3 7.2 56.9 3.6 2 1 0 2 2 2 0 Intermediate filament protein DUF724 PF05266.14 KEY69487.1 - 3.2 7.5 0.0 3.2 7.5 0.0 5.7 3 1 3 6 6 4 0 Protein of unknown function (DUF724) OPT PF03169.15 KEY69488.1 - 4.4e-153 511.2 15.0 5e-153 511.0 15.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Rav1p_C PF12234.8 KEY69489.1 - 8.6e-273 906.5 0.1 8.7e-272 903.2 0.1 2.0 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KEY69489.1 - 0.12 13.3 2.8 46 5.1 0.0 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat NDUF_B7 PF05676.13 KEY69490.1 - 0.0094 15.7 2.1 1 9.1 0.1 2.2 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KEY69490.1 - 0.011 15.7 2.0 0.018 15.0 2.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KEY69490.1 - 0.052 13.6 2.4 0.054 13.5 1.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3581 PF12119.8 KEY69490.1 - 0.096 12.1 0.2 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3581) CHCH PF06747.13 KEY69490.1 - 0.23 11.6 5.0 2.5 8.3 4.5 2.1 1 1 1 2 2 2 0 CHCH domain tRNA-synt_1 PF00133.22 KEY69491.1 - 1.3e-224 746.9 0.0 1.9e-224 746.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEY69491.1 - 7.2e-26 91.0 0.0 5.3e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEY69491.1 - 6.8e-17 61.3 0.3 6e-08 31.9 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KEY69491.1 - 0.0039 16.6 0.0 0.049 13.0 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 KEY69492.1 - 1.2e-129 432.3 0.0 1.4e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Sec7_N PF12783.7 KEY69492.1 - 0.043 13.7 1.3 0.82 9.6 0.0 2.8 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SWIB PF02201.18 KEY69493.1 - 5.8e-21 74.2 0.0 1.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.25 KEY69494.1 - 2.5e-68 230.3 0.0 3.4e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69494.1 - 1.2e-34 119.8 0.0 2.3e-24 86.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY69494.1 - 1.7e-05 24.3 0.6 0.011 15.1 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEY69494.1 - 0.00096 18.6 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEY69494.1 - 0.0021 17.1 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEY69494.1 - 0.0064 16.4 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KEY69494.1 - 0.025 14.2 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4025 PF13217.6 KEY69494.1 - 0.046 13.6 0.1 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4025) 2_5_RNA_ligase2 PF13563.6 KEY69495.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily ANAPC_CDC26 PF10471.9 KEY69495.1 - 0.057 14.3 3.3 0.1 13.4 0.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SNARE PF05739.19 KEY69497.1 - 4.5e-09 36.2 5.1 9.1e-09 35.2 2.0 2.3 2 0 0 2 2 2 1 SNARE domain Fusion_gly PF00523.18 KEY69497.1 - 0.11 10.8 0.2 0.14 10.3 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 EVI2A PF05399.11 KEY69497.1 - 0.31 10.6 1.1 15 5.1 0.5 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DGF-1_C PF11040.8 KEY69497.1 - 0.7 9.9 3.7 2.8 8.0 3.7 2.2 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus ANAPC4_WD40 PF12894.7 KEY69498.1 - 3e-06 27.4 0.1 0.033 14.5 0.0 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY69498.1 - 0.00031 21.5 4.6 0.011 16.6 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Glyco_hydro_18 PF00704.28 KEY69499.1 - 2.6e-88 296.8 1.5 3e-88 296.6 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PPTA PF01239.22 KEY69500.1 - 9.7e-34 114.1 11.9 1.2e-08 34.4 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4603 PF15376.6 KEY69500.1 - 0.7 7.2 4.2 0.96 6.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) His_Phos_2 PF00328.22 KEY69501.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) TALPID3 PF15324.6 KEY69501.1 - 4.2 4.9 4.2 5.7 4.5 4.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target zf-4CXXC_R1 PF10497.9 KEY69502.1 - 9e-10 38.7 9.2 9e-10 38.7 9.2 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 KEY69502.1 - 1.9e-09 37.9 0.1 5.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KEY69502.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Ribosomal_L5 PF00281.19 KEY69502.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 TSGP1 PF07771.11 KEY69502.1 - 5.9 7.1 10.6 0.2 11.8 3.1 2.4 2 0 0 2 2 2 0 Tick salivary peptide group 1 UbiA PF01040.18 KEY69503.1 - 2.4e-42 145.0 20.0 3.2e-42 144.6 20.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 KEY69504.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KEY69505.1 - 3.2e-26 91.0 2.7 3.4e-26 90.9 1.0 1.9 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Sporozoite_P67 PF05642.11 KEY69505.1 - 0.93 7.5 6.7 1.7 6.7 6.2 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen HOOK PF05622.12 KEY69507.1 - 0.0003 19.1 79.8 0.065 11.4 0.8 4.1 3 1 1 4 4 4 3 HOOK protein Alliinase_C PF04864.13 KEY69507.1 - 0.0021 17.0 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Allinase PG_binding_1 PF01471.18 KEY69507.1 - 0.15 12.2 2.0 0.57 10.4 0.1 2.9 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF2321 PF10083.9 KEY69507.1 - 4.8 6.8 5.7 1.1 8.9 1.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ADK PF00406.22 KEY69508.1 - 1.7e-58 197.0 0.0 2.4e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEY69508.1 - 2.4e-22 79.8 0.0 6.9e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KEY69508.1 - 1.4e-16 60.2 0.0 4.9e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KEY69508.1 - 0.00019 22.0 0.0 0.00055 20.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY69508.1 - 0.0007 19.8 0.0 0.0014 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Paramyx_P_V_C PF03210.13 KEY69508.1 - 0.0089 15.8 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal Trimer_CC PF08954.11 KEY69508.1 - 0.049 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif DUF4200 PF13863.6 KEY69508.1 - 0.084 13.3 0.2 0.25 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2802 PF10975.8 KEY69508.1 - 0.087 13.0 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) AAA_24 PF13479.6 KEY69508.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MitMem_reg PF13012.6 KEY69509.1 - 3.3e-37 127.3 0.0 8.8e-37 126.0 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KEY69509.1 - 3.4e-31 107.7 0.3 6.8e-31 106.7 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KEY69509.1 - 0.074 12.7 2.1 0.11 12.2 2.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain DUF809 PF05663.11 KEY69509.1 - 0.41 10.8 3.5 0.85 9.8 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) SWIM PF04434.17 KEY69510.1 - 0.012 15.2 7.2 0.11 12.2 0.0 2.8 3 0 0 3 3 3 0 SWIM zinc finger Coprogen_oxidas PF01218.18 KEY69511.1 - 2.6e-144 479.4 0.1 3.1e-144 479.2 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 KEY69512.1 - 2.5e-51 172.2 0.2 3e-51 172.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEY69512.1 - 4.1e-06 27.1 0.0 4.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Methyltransf_11 PF08241.12 KEY69513.1 - 1.7e-19 70.3 0.0 3.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69513.1 - 2.2e-18 66.6 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69513.1 - 6.9e-17 61.9 0.1 2e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEY69513.1 - 8.3e-17 61.4 0.0 2.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KEY69513.1 - 5.9e-15 55.8 0.1 9.7e-14 51.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69513.1 - 1.7e-14 53.9 0.0 8.9e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY69513.1 - 2e-07 30.6 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 KEY69513.1 - 1.7e-05 24.5 0.0 5.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 KEY69513.1 - 0.00028 20.5 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 KEY69513.1 - 0.001 18.7 0.1 0.057 13.0 0.1 2.8 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KEY69513.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KEY69513.1 - 0.029 14.4 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KEY69513.1 - 0.037 13.8 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KEY69513.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 EspB PF05802.11 KEY69514.1 - 0.04 13.9 0.7 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Enterobacterial EspB protein Baculo_PEP_C PF04513.12 KEY69514.1 - 0.046 13.8 3.0 2.8 8.0 0.5 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Shisa PF13908.6 KEY69514.1 - 0.25 11.5 1.9 2.7 8.2 0.0 2.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator SAMP PF05924.11 KEY69514.1 - 4.8 6.6 6.5 0.22 10.8 0.8 1.9 2 0 0 2 2 2 0 SAMP Motif Trp_syntA PF00290.20 KEY69515.1 - 8.7e-96 319.7 0.0 1.5e-95 319.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KEY69515.1 - 1.4e-49 169.1 1.4 4.1e-49 167.6 1.9 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.19 KEY69516.1 - 1e-11 44.8 0.9 1.6e-11 44.2 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HAUS4 PF14735.6 KEY69517.1 - 0.1 12.3 0.1 0.3 10.8 0.0 1.7 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 4 Aminotran_1_2 PF00155.21 KEY69518.1 - 1.6e-91 307.2 0.0 1.8e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.24 KEY69519.1 - 1.1e-76 258.6 20.6 1.4e-76 258.2 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69519.1 - 4.6e-15 55.4 31.1 2.8e-12 46.2 6.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily HhH-GPD PF00730.25 KEY69519.1 - 0.00032 21.1 0.0 0.00072 20.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein adh_short PF00106.25 KEY69521.1 - 3.9e-28 98.2 0.0 1.5e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69521.1 - 6.3e-17 61.9 0.0 6.7e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69521.1 - 1.2e-07 31.8 0.0 5.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KEY69521.1 - 0.00045 19.7 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KEY69521.1 - 0.0022 18.1 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KEY69521.1 - 0.0076 15.7 0.1 0.019 14.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY69521.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KEY69521.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 KEY69521.1 - 0.16 11.6 0.3 0.37 10.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HTH_8 PF02954.19 KEY69522.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sugar_tr PF00083.24 KEY69524.1 - 4.8e-110 368.5 17.3 3.2e-87 293.3 8.7 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEY69524.1 - 2.1e-21 76.3 34.0 2.8e-21 75.9 27.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1992 PF09350.10 KEY69525.1 - 1.6e-20 73.0 0.4 4.4e-20 71.6 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MFS_1 PF07690.16 KEY69526.1 - 1e-22 80.5 31.3 1e-22 80.5 31.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY69526.1 - 1.1e-11 44.2 24.5 2.2e-11 43.3 24.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 KEY69526.1 - 0.012 15.7 0.3 0.021 14.8 0.3 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Entericidin PF08085.11 KEY69526.1 - 0.058 13.4 0.5 0.058 13.4 0.5 1.9 2 0 0 2 2 2 0 Entericidin EcnA/B family WD40 PF00400.32 KEY69527.1 - 8.8e-55 181.5 23.7 5.7e-08 33.3 0.5 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69527.1 - 9e-13 48.3 0.1 0.0054 17.0 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY69527.1 - 1.3e-06 27.4 0.9 0.0021 16.8 0.0 3.6 4 1 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEY69527.1 - 0.0052 15.6 0.0 2.2 6.9 0.0 2.9 2 1 0 3 3 3 2 Nup133 N terminal like DUF1040 PF06288.13 KEY69528.1 - 0.0078 16.6 1.5 0.015 15.6 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) DUF2183 PF09949.9 KEY69529.1 - 1.9e-28 98.7 0.0 5e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) S36_mt PF10937.8 KEY69530.1 - 3.2e-41 141.5 1.0 4.1e-41 141.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial AA_permease PF00324.21 KEY69531.1 - 2.4e-142 474.9 41.5 2.8e-142 474.7 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY69531.1 - 3.3e-36 125.1 42.6 4.3e-36 124.7 42.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1741 PF08427.10 KEY69532.1 - 2.6e-90 302.2 0.1 4.4e-90 301.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) RasGEF PF00617.19 KEY69534.1 - 4.5e-53 180.1 0.1 8.6e-53 179.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEY69534.1 - 2.8e-16 59.7 0.0 7.9e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KEY69534.1 - 5.9e-06 26.0 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY69534.1 - 8.4e-05 22.1 0.0 0.00034 20.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KEY69534.1 - 0.025 14.3 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain MFS_1 PF07690.16 KEY69535.1 - 2.4e-16 59.6 30.9 2.4e-16 59.6 30.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEY69535.1 - 2.8e-09 36.9 6.8 5.2e-09 36.0 5.1 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2208 PF09973.9 KEY69535.1 - 0.0081 15.8 0.2 0.021 14.5 0.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) MFS_1_like PF12832.7 KEY69535.1 - 0.17 10.7 16.6 0.021 13.7 7.5 2.5 1 1 1 3 3 3 0 MFS_1 like family ATP-grasp_2 PF08442.10 KEY69536.1 - 5.7e-75 251.3 0.4 5.7e-75 251.3 0.4 1.6 2 0 0 2 2 2 1 ATP-grasp domain DNA_binding_1 PF01035.20 KEY69536.1 - 7.7e-30 102.9 0.4 3.5e-29 100.8 0.0 2.3 3 0 0 3 3 3 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ligase_CoA PF00549.19 KEY69536.1 - 1.9e-26 92.7 0.4 3.4e-26 91.9 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Fe-S_biosyn PF01521.20 KEY69536.1 - 2.1e-15 56.9 0.0 5.8e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis ATP-grasp_5 PF13549.6 KEY69536.1 - 2.7e-07 30.3 0.1 4.8e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KEY69536.1 - 0.0019 18.0 1.1 0.043 13.6 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ank_2 PF12796.7 KEY69537.1 - 3.1e-64 213.6 0.0 7.8e-16 58.4 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY69537.1 - 1.1e-28 96.0 0.0 0.00084 19.6 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KEY69537.1 - 1.4e-27 94.9 0.0 2.8e-05 24.4 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KEY69537.1 - 5.2e-26 90.7 0.0 1.1e-10 41.8 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY69537.1 - 3.6e-18 65.4 0.0 5.1e-05 23.5 0.0 6.4 2 2 5 7 7 7 4 Ankyrin repeats (many copies) HET PF06985.11 KEY69537.1 - 1.5e-10 41.6 5.7 2.4e-08 34.5 0.9 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KEY69537.1 - 5.1e-05 23.3 0.1 0.00014 21.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY69537.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY69537.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KEY69537.1 - 0.053 12.7 1.0 0.21 10.8 0.1 2.2 2 1 0 3 3 3 0 KAP family P-loop domain RNA_helicase PF00910.22 KEY69537.1 - 0.061 13.7 0.1 0.23 11.9 0.1 2.0 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 KEY69537.1 - 0.11 11.5 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Fructosamin_kin PF03881.14 KEY69538.1 - 3.5e-72 243.0 0.0 4.1e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEY69538.1 - 7.9e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEY69538.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Snf7 PF03357.21 KEY69539.1 - 1.9e-35 122.0 10.9 2.4e-35 121.7 10.9 1.1 1 0 0 1 1 1 1 Snf7 BORCS7 PF16088.5 KEY69539.1 - 0.14 12.5 2.5 0.28 11.4 2.5 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 NPV_P10 PF05531.12 KEY69539.1 - 0.66 10.5 6.2 11 6.5 0.0 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA PF00004.29 KEY69540.1 - 1.1e-61 207.1 0.0 4.6e-45 153.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY69540.1 - 1.1e-11 44.3 0.2 3.8e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KEY69540.1 - 2.3e-09 37.9 0.3 0.00084 19.8 0.0 4.2 4 1 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 KEY69540.1 - 3.8e-07 30.2 0.0 0.00047 20.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEY69540.1 - 5e-07 29.6 0.0 0.0011 18.8 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEY69540.1 - 2e-05 24.9 0.0 0.012 15.9 0.0 3.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KEY69540.1 - 7.2e-05 23.0 0.0 0.0058 16.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KEY69540.1 - 0.00011 22.3 0.0 0.00058 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KEY69540.1 - 0.00025 21.0 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KEY69540.1 - 0.0003 20.8 0.0 0.011 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KEY69540.1 - 0.00057 19.2 0.1 0.2 10.8 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 KEY69540.1 - 0.0011 19.3 0.0 0.046 14.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 KEY69540.1 - 0.0011 18.4 0.0 2.3 7.6 0.0 3.0 3 0 0 3 3 3 2 Bacterial TniB protein AAA_18 PF13238.6 KEY69540.1 - 0.0013 19.3 0.1 0.97 10.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KEY69540.1 - 0.0015 18.3 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KEY69540.1 - 0.0026 17.9 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 KEY69540.1 - 0.0032 17.4 0.1 0.88 9.5 0.0 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 KEY69540.1 - 0.0035 17.1 0.2 0.27 10.9 0.0 3.1 3 1 0 3 3 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 KEY69540.1 - 0.004 16.4 0.0 0.12 11.7 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin DUF815 PF05673.13 KEY69540.1 - 0.0085 15.3 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KEY69540.1 - 0.009 15.4 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KEY69540.1 - 0.014 14.9 0.0 0.79 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEY69540.1 - 0.02 14.8 0.3 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 KEY69540.1 - 0.033 14.7 0.2 1.5 9.3 0.0 3.0 3 1 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 KEY69540.1 - 0.034 13.7 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KEY69540.1 - 0.059 13.1 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KEY69540.1 - 0.06 13.8 0.2 1.8 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 KEY69540.1 - 0.074 12.8 1.7 0.58 9.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Cytochrom_C PF00034.21 KEY69541.1 - 1.2e-12 48.8 0.1 1.6e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KEY69541.1 - 1.4e-09 38.1 1.9 4.9e-09 36.4 1.9 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KEY69541.1 - 0.01 15.6 0.2 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain RNase_PH PF01138.21 KEY69543.1 - 1.3e-13 51.6 0.0 2.3e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEY69543.1 - 0.024 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ATE_C PF04377.15 KEY69544.1 - 3.9e-48 163.5 0.5 6.4e-48 162.8 0.5 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KEY69544.1 - 3.7e-21 75.3 0.1 8.2e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KEY69544.1 - 0.0071 16.5 1.0 0.032 14.4 0.1 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KEY69545.1 - 2.1e-18 66.6 0.6 2.5e-18 66.4 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain Tox-MPTase3 PF15639.6 KEY69545.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 3 LSM PF01423.22 KEY69546.1 - 1.1e-12 47.5 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain MMU163 PF17119.5 KEY69547.1 - 8.5e-73 244.6 7.7 4.5e-54 183.2 1.7 2.0 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Ras PF00071.22 KEY69548.1 - 2.2e-64 216.0 0.5 2.6e-64 215.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY69548.1 - 3.9e-35 120.7 0.1 7.2e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY69548.1 - 3.5e-16 59.1 0.1 4.4e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEY69548.1 - 1e-05 25.5 0.6 0.077 12.9 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEY69548.1 - 1.3e-05 25.2 0.0 9.9e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY69548.1 - 7e-05 22.5 0.3 0.00019 21.0 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KEY69548.1 - 0.00022 21.7 0.1 0.049 14.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 KEY69548.1 - 0.00023 20.6 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEY69548.1 - 0.00033 20.2 0.1 0.00049 19.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KEY69548.1 - 0.00075 19.1 0.1 0.0078 15.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KEY69548.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY69548.1 - 0.039 14.2 0.0 0.069 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY69548.1 - 0.049 13.6 0.1 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEY69548.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KEY69548.1 - 0.067 12.5 0.1 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 KEY69548.1 - 0.086 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KEY69548.1 - 0.094 12.5 0.1 0.93 9.2 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KEY69548.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Troponin-I_N PF11636.8 KEY69550.1 - 0.13 12.3 1.5 7.9 6.5 0.4 2.3 2 0 0 2 2 2 0 Troponin I residues 1-32 WD40 PF00400.32 KEY69551.1 - 1.4e-13 51.0 10.7 0.0038 18.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.6 KEY69551.1 - 1.3e-05 24.9 1.1 0.054 13.1 0.1 3.1 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 KEY69551.1 - 0.00014 22.3 0.8 0.14 12.7 0.0 4.1 5 1 0 5 5 5 1 PQQ-like domain Nup160 PF11715.8 KEY69551.1 - 0.0012 17.7 0.4 0.31 9.7 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEY69551.1 - 0.032 13.2 0.0 0.077 11.9 0.0 1.6 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Sigma70_r1_2 PF00140.20 KEY69551.1 - 0.077 13.0 0.6 0.18 11.8 0.6 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Mcl1_mid PF12341.8 KEY69552.1 - 1.1e-97 327.0 0.0 3.3e-97 325.4 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KEY69552.1 - 1.5e-18 66.8 3.3 1e-05 26.2 0.0 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69552.1 - 3.4e-16 59.3 0.4 0.00046 20.4 0.1 6.7 2 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KEY69552.1 - 1.1e-07 31.4 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region DNA_pol_alpha_N PF12254.8 KEY69552.1 - 0.00011 22.2 0.3 0.0025 17.8 2.2 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal eIF2A PF08662.11 KEY69552.1 - 0.0012 18.7 0.2 0.046 13.6 0.3 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.9 KEY69552.1 - 0.037 12.7 0.0 0.37 9.4 0.0 2.5 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 KEY69552.1 - 0.068 12.1 0.0 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KEY69552.1 - 0.07 11.1 0.1 0.18 9.8 0.1 1.6 1 1 0 1 1 1 0 IKI3 family KTSC PF13619.6 KEY69552.1 - 0.11 12.4 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 KTSC domain TFIIIC_delta PF12657.7 KEY69552.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term PBP1_TM PF14812.6 KEY69552.1 - 2.5 8.5 9.3 0.34 11.3 4.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf_CCCH_4 PF18345.1 KEY69553.1 - 0.14 12.3 2.3 0.25 11.4 2.3 1.5 1 0 0 1 1 1 0 Zinc finger domain PP-binding PF00550.25 KEY69554.1 - 2.3e-11 43.9 0.1 3.1e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KEY69554.1 - 1.3e-05 25.3 0.1 1.6e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Peptidase_M14 PF00246.24 KEY69555.1 - 4.5e-38 131.7 0.1 6.3e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KEY69555.1 - 0.0065 15.6 0.0 5.4 6.0 0.0 3.3 4 0 0 4 4 4 2 Succinylglutamate desuccinylase / Aspartoacylase family FimA PF16970.5 KEY69555.1 - 0.078 13.2 0.1 3 8.0 0.0 2.6 3 0 0 3 3 3 0 Type-1 fimbrial protein, A Fer4 PF00037.27 KEY69556.1 - 1.4e-13 50.0 16.5 5.6e-08 32.3 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEY69556.1 - 8.7e-13 48.6 10.2 1.4e-12 48.0 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEY69556.1 - 1.9e-10 41.5 7.0 7.1e-05 23.7 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KEY69556.1 - 9.1e-10 38.5 31.2 4.7e-06 26.6 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEY69556.1 - 1.2e-08 34.9 21.3 2.5e-06 27.5 12.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEY69556.1 - 3.9e-08 33.3 10.0 8.3e-08 32.3 10.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEY69556.1 - 4e-07 30.4 19.2 0.00011 22.6 11.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEY69556.1 - 1.2e-06 28.4 17.1 0.00036 20.5 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KEY69556.1 - 4.1e-06 26.6 11.8 0.009 16.1 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KEY69556.1 - 7.7e-06 26.0 11.4 0.00027 21.2 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KEY69556.1 - 0.00027 21.4 11.6 0.049 14.2 12.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KEY69556.1 - 0.0056 16.9 5.5 0.72 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 KEY69556.1 - 0.039 14.1 5.2 0.19 11.9 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 KEY69556.1 - 0.055 13.7 8.7 0.96 9.7 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEY69556.1 - 0.059 13.9 15.0 0.69 10.5 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEY69556.1 - 0.21 12.6 15.5 0.39 11.8 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KEY69556.1 - 0.59 11.0 11.7 2.3 9.1 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain F-box-like PF12937.7 KEY69558.1 - 0.00027 20.8 0.0 0.00027 20.8 0.0 3.8 5 0 0 5 5 5 1 F-box-like F-box PF00646.33 KEY69558.1 - 0.0012 18.6 1.7 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain EII-Sor PF03609.14 KEY69558.1 - 0.0054 16.2 0.4 0.012 15.1 0.3 1.6 1 1 0 1 1 1 1 PTS system sorbose-specific iic component EHN PF06441.12 KEY69559.1 - 4.9e-33 113.7 0.1 5.5e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEY69559.1 - 4.2e-10 39.7 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY69559.1 - 0.0012 19.5 6.6 0.0025 18.4 6.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family TonB_N PF16031.5 KEY69560.1 - 0.007 16.9 10.3 0.015 15.8 10.3 1.5 1 0 0 1 1 1 1 TonB polyproline region Sugar_tr PF00083.24 KEY69561.1 - 2.8e-78 263.8 15.4 3.4e-78 263.5 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69561.1 - 1.7e-32 112.7 20.6 8.1e-31 107.2 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KEY69562.1 - 4.4e-11 42.6 2.6 2.3e-06 27.1 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEY69562.1 - 1.8e-09 37.7 0.0 3.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY69562.1 - 7.2e-07 28.7 0.6 0.023 14.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY69562.1 - 0.0002 21.5 0.1 0.001 19.3 0.1 2.2 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY69562.1 - 0.00021 20.5 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY69562.1 - 0.0013 17.5 0.1 0.36 9.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KEY69562.1 - 0.0021 17.4 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY69562.1 - 0.0056 17.2 0.2 1.4 9.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY69562.1 - 0.02 14.3 0.2 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 KEY69563.1 - 2.8e-15 56.3 0.4 4.4e-15 55.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69563.1 - 9.4e-05 22.4 0.0 0.00025 21.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like RhgB_N PF09284.10 KEY69565.1 - 1.8e-75 253.7 0.7 2.7e-75 253.2 0.7 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal fn3_3 PF14686.6 KEY69565.1 - 1.1e-16 60.3 7.6 1.1e-16 60.3 7.6 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KEY69565.1 - 8.8e-15 55.0 0.0 3.1e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 KEY69565.1 - 0.077 13.3 10.0 0.16 12.2 3.7 3.5 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KEY69565.1 - 0.73 9.9 3.2 0.72 9.9 1.1 2.2 2 0 0 2 2 2 0 CarboxypepD_reg-like domain NMU PF02070.15 KEY69567.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Neuromedin U SAPS PF04499.15 KEY69567.1 - 0.13 11.0 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein p450 PF00067.22 KEY69568.1 - 4.4e-46 157.6 0.0 5.8e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KEY69569.1 - 1.3e-17 63.9 0.0 8.3e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69569.1 - 3.4e-09 36.6 0.0 8.7e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY69569.1 - 0.002 17.6 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY69569.1 - 0.0026 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KEY69569.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KEY69569.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1929 PF09118.11 KEY69570.1 - 2.4e-23 82.2 0.1 5.2e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KEY69570.1 - 6.6e-13 48.4 1.6 4.5e-05 23.6 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KEY69570.1 - 1.1e-10 40.9 0.1 0.00015 21.2 0.1 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KEY69570.1 - 4.1e-07 29.7 1.0 0.097 12.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KEY69570.1 - 6.8e-06 26.0 12.0 0.0047 16.9 0.1 6.1 5 2 0 5 5 5 1 Galactose oxidase, central domain PAN_1 PF00024.26 KEY69570.1 - 1.6e-05 24.8 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PAN domain Glyoxal_oxid_N PF07250.11 KEY69570.1 - 0.00033 19.9 0.0 0.33 10.1 0.0 2.5 2 1 1 3 3 3 3 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 KEY69570.1 - 0.0062 16.8 0.4 0.56 10.6 0.0 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Ig_3 PF13927.6 KEY69570.1 - 0.089 13.4 0.3 5 7.8 0.1 2.7 3 0 0 3 3 3 0 Immunoglobulin domain PAN_4 PF14295.6 KEY69570.1 - 0.099 12.6 4.6 0.064 13.2 2.2 1.9 2 0 0 2 2 2 0 PAN domain FAD_binding_4 PF01565.23 KEY69571.1 - 1e-18 67.4 3.5 1.9e-18 66.5 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69571.1 - 1.2e-08 34.9 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like SUN PF03856.13 KEY69571.1 - 0.089 12.2 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Cu-oxidase_2 PF07731.14 KEY69572.1 - 9.4e-30 103.1 3.7 5.6e-26 90.9 0.5 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY69572.1 - 3.8e-21 75.3 0.2 1.4e-20 73.5 0.2 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY69572.1 - 0.00056 20.1 0.1 0.046 13.8 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase DUF4470 PF14737.6 KEY69574.1 - 6.6e-24 83.9 0.1 1.4e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEY69574.1 - 2.5e-09 37.1 11.9 6.5e-09 35.7 11.9 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KEY69574.1 - 0.0061 16.8 5.3 0.015 15.6 5.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Pectinesterase PF01095.19 KEY69575.1 - 4.9e-48 163.4 6.2 6e-48 163.1 6.2 1.0 1 0 0 1 1 1 1 Pectinesterase CFEM PF05730.11 KEY69576.1 - 6.9e-07 29.3 6.2 1.2e-06 28.5 6.2 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 KEY69577.1 - 3e-10 40.0 7.5 4.4e-10 39.5 7.5 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 KEY69577.1 - 0.033 14.6 4.2 0.034 14.6 3.7 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NAD_binding_8 PF13450.6 KEY69577.1 - 0.3 11.4 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KEY69578.1 - 3.1e-12 46.1 57.7 2.4e-10 39.9 57.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Caleosin PF05042.13 KEY69579.1 - 4.6e-81 270.7 0.2 5.5e-81 270.5 0.2 1.0 1 0 0 1 1 1 1 Caleosin related protein FAD_binding_8 PF08022.12 KEY69580.1 - 5.5e-18 65.0 0.0 1.3e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KEY69580.1 - 2.5e-12 47.0 4.0 5.5e-12 45.9 4.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY69580.1 - 2.3e-11 44.1 0.0 1.1e-10 41.8 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 KEY69580.1 - 0.0028 18.1 0.3 0.012 16.1 0.5 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEY69580.1 - 0.0084 15.6 0.3 0.026 14.1 0.3 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KEY69580.1 - 0.017 15.0 0.3 0.053 13.5 0.3 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KEY69580.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 EF hand Glyco_hydro_61 PF03443.14 KEY69581.1 - 6.5e-56 189.5 0.0 7.5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CHRD PF07452.12 KEY69582.1 - 1.6e-11 45.2 0.0 2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 CHRD domain Glyco_hydro_7 PF00840.20 KEY69583.1 - 1.4e-173 577.6 7.2 1.7e-173 577.4 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Esterase_phd PF10503.9 KEY69584.1 - 1.7e-23 83.3 0.5 2.3e-23 82.8 0.5 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEY69584.1 - 7e-10 38.7 0.1 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEY69584.1 - 0.048 12.9 0.3 0.52 9.5 0.2 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KEY69584.1 - 0.08 12.6 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 KEY69584.1 - 0.1 12.4 0.8 0.38 10.5 0.8 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 KEY69584.1 - 0.22 11.1 1.0 0.41 10.2 1.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Rib_recp_KP_reg PF05104.12 KEY69585.1 - 0.35 11.9 4.4 0.51 11.4 4.4 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Ferric_reduct PF01794.19 KEY69585.1 - 0.46 10.6 10.7 0.18 11.9 7.4 2.0 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Sugar_tr PF00083.24 KEY69586.1 - 1.4e-79 268.1 15.6 1.6e-79 267.9 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69586.1 - 9.6e-22 77.4 10.4 9.6e-22 77.4 10.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF554 PF04474.12 KEY69586.1 - 0.0074 15.8 1.3 0.0074 15.8 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF554) Sulfotransfer_4 PF17784.1 KEY69587.1 - 4.5e-60 203.1 0.0 5.3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain DUF763 PF05559.11 KEY69588.1 - 0.11 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Abhydrolase_1 PF00561.20 KEY69589.1 - 2.3e-23 83.1 0.3 7.9e-22 78.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY69589.1 - 5.3e-15 56.6 0.3 7.6e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY69589.1 - 1.7e-13 50.4 0.0 1.8e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEY69589.1 - 8.2e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KEY69589.1 - 2.1e-05 24.1 0.1 0.048 13.1 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Ndr PF03096.14 KEY69589.1 - 0.059 12.1 0.0 7.9 5.1 0.0 2.6 3 0 0 3 3 3 0 Ndr family FSH1 PF03959.13 KEY69589.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MFS_1 PF07690.16 KEY69590.1 - 4.7e-39 134.3 35.0 4.7e-39 134.3 35.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KEY69590.1 - 6.3e-09 35.6 2.8 1.9e-08 34.0 2.8 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KEY69590.1 - 1.7e-08 33.8 22.9 4.3e-08 32.4 22.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter NmrA PF05368.13 KEY69591.1 - 1e-56 192.2 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY69591.1 - 2.3e-13 50.5 0.1 3.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY69591.1 - 0.011 14.7 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY69591.1 - 0.036 13.5 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY69591.1 - 0.07 13.4 0.1 0.38 11.0 0.0 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NolV PF06635.12 KEY69591.1 - 0.11 11.9 0.7 0.16 11.3 0.2 1.5 2 0 0 2 2 2 0 Nodulation protein NolV HET PF06985.11 KEY69592.1 - 5.7e-28 98.1 0.1 2.7e-27 95.9 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FMN_dh PF01070.18 KEY69593.1 - 9.9e-103 343.8 1.4 2.9e-102 342.3 1.4 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEY69593.1 - 7.4e-12 45.2 0.0 2.8e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEY69593.1 - 2.4e-06 26.9 0.3 4.3e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY69593.1 - 1.5e-05 24.2 1.5 8.8e-05 21.7 0.5 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEY69593.1 - 0.0054 16.1 1.4 0.82 8.9 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KEY69593.1 - 0.01 15.1 0.0 0.066 12.4 0.1 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KEY69593.1 - 0.029 13.8 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 KEY69593.1 - 0.035 13.5 0.6 0.053 12.9 0.6 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF3433 PF11915.8 KEY69594.1 - 5.1e-24 84.5 17.5 1.1e-17 64.2 4.8 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) FAD_binding_4 PF01565.23 KEY69596.1 - 2.6e-21 75.8 0.9 4.9e-21 74.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Methyltransf_31 PF13847.6 KEY69597.1 - 1.9e-05 24.5 0.0 0.13 12.1 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 KEY69597.1 - 2.1e-05 24.4 0.0 3.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69597.1 - 0.00032 21.4 0.0 0.016 15.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69597.1 - 0.029 15.0 0.0 0.56 10.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KEY69598.1 - 8e-18 64.6 0.0 1.6e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY69598.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY69598.1 - 0.00021 20.9 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY69598.1 - 0.0003 20.3 0.0 0.001 18.6 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY69598.1 - 0.094 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 KEY69599.1 - 1.3e-35 123.0 0.0 1.8e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY69600.1 - 1.4e-18 67.0 6.3 6e-18 64.9 6.3 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69600.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KEY69601.1 - 1.1e-35 123.3 0.0 3.3e-35 121.7 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY69603.1 - 4.8e-22 78.2 1.9 7.6e-22 77.5 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY69603.1 - 0.0007 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PLA2_B PF01735.18 KEY69604.1 - 3.7e-16 58.6 0.0 1.2e-07 30.6 0.0 2.6 2 1 0 2 2 2 2 Lysophospholipase catalytic domain HET PF06985.11 KEY69605.1 - 2.7e-09 37.5 6.3 9.7e-07 29.2 1.8 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY69606.1 - 4.5e-29 101.7 0.9 5.9e-27 94.8 0.9 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KEY69607.1 - 6.9e-43 146.9 0.0 9.3e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY69607.1 - 2.8e-39 134.6 0.0 3.6e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 KEY69607.1 - 0.019 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KEY69607.1 - 0.039 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KEY69607.1 - 0.12 12.2 0.1 0.47 10.3 0.1 1.9 1 1 0 1 1 1 0 KR domain DUF2284 PF10050.9 KEY69608.1 - 1.7 8.4 37.1 0.089 12.5 0.8 5.3 6 1 1 7 7 7 0 Predicted metal-binding protein (DUF2284) RTA1 PF04479.13 KEY69609.1 - 1.5e-59 201.1 10.4 1.5e-59 201.1 10.4 2.0 2 0 0 2 2 2 1 RTA1 like protein Aldedh PF00171.22 KEY69611.1 - 3.4e-144 480.8 0.0 4e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family peroxidase PF00141.23 KEY69612.1 - 2e-88 296.0 0.0 1.2e-44 152.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 KEY69612.1 - 0.012 15.8 0.0 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY69612.1 - 0.072 13.3 0.0 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Prefoldin_2 PF01920.20 KEY69613.1 - 0.079 12.9 0.2 3.1 7.8 0.0 2.8 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 KEY69613.1 - 0.16 12.4 1.4 9.9 6.6 0.1 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 KEY69613.1 - 0.38 10.8 4.1 15 5.7 0.2 3.1 3 0 0 3 3 3 0 Short coiled-coil protein ICMT PF04140.14 KEY69614.1 - 1.4e-10 41.4 0.1 3.5e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KEY69614.1 - 1e-07 32.3 0.5 1.6e-06 28.4 0.1 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KEY69614.1 - 0.0019 17.1 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 KEY69614.1 - 0.0078 15.7 1.2 0.026 14.0 0.0 2.2 2 1 0 2 2 2 1 NnrU protein EmrE PF13536.6 KEY69615.1 - 0.18 11.4 13.4 0.018 14.7 8.4 1.9 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter Ank_2 PF12796.7 KEY69616.1 - 1.7e-26 92.6 9.9 4.5e-12 46.4 2.2 8.2 6 2 2 9 9 9 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY69616.1 - 1.3e-25 86.6 15.4 0.013 16.0 0.1 11.9 11 0 0 11 11 11 5 Ankyrin repeat Ank_4 PF13637.6 KEY69616.1 - 5.2e-19 68.4 7.1 3.6e-07 30.6 0.1 9.4 9 1 2 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 KEY69616.1 - 1.2e-12 47.7 21.1 0.00042 20.6 0.1 8.9 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KEY69616.1 - 2.1e-12 47.0 16.7 8.6e-05 22.8 0.2 8.2 6 1 3 9 9 9 4 Ankyrin repeats (many copies) adh_short PF00106.25 KEY69617.1 - 5e-29 101.2 0.4 5.5e-23 81.4 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69617.1 - 4.9e-21 75.4 0.5 9.4e-20 71.2 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69617.1 - 1.1e-07 31.9 0.8 1.1e-07 31.9 0.8 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY69617.1 - 0.0016 17.9 1.0 0.0029 17.1 1.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY69617.1 - 0.031 14.2 0.4 0.059 13.3 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H-binding PhoLip_ATPase_C PF16212.5 KEY69618.1 - 2.9e-83 279.4 16.7 2.9e-83 279.4 16.7 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEY69618.1 - 4.5e-27 93.5 6.2 1.1e-26 92.2 6.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KEY69618.1 - 7.7e-12 45.1 0.0 6.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEY69618.1 - 4.9e-11 43.3 3.2 8.7e-07 29.4 0.8 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEY69618.1 - 7.6e-08 32.1 0.1 1.9e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEY69618.1 - 0.0017 18.1 0.3 0.0054 16.5 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cript PF10235.9 KEY69619.1 - 2.7e-23 82.3 9.4 2.7e-23 82.3 9.4 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 KEY69619.1 - 0.0013 19.0 11.1 0.012 15.9 8.6 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) SARG PF15385.6 KEY69619.1 - 0.0089 15.3 0.2 0.01 15.1 0.2 1.1 1 0 0 1 1 1 1 Specifically androgen-regulated gene protein DZR PF12773.7 KEY69619.1 - 0.016 15.2 11.1 0.24 11.5 8.7 2.6 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KEY69619.1 - 0.14 13.0 8.8 0.076 13.8 5.1 2.3 2 1 0 2 2 2 0 zinc-ribbon family zf-C3HC4_3 PF13920.6 KEY69619.1 - 2.1 8.3 12.6 33 4.4 9.6 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_1 PF00561.20 KEY69620.1 - 5.6e-20 72.1 0.0 3.2e-19 69.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY69620.1 - 1.8e-14 54.9 1.9 2.7e-14 54.3 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY69620.1 - 3.2e-08 33.1 0.0 6.4e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEY69620.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Zeta_toxin PF06414.12 KEY69621.1 - 1.5e-12 47.3 0.0 2.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KEY69621.1 - 1.1e-11 45.0 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY69621.1 - 3e-05 24.6 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KEY69621.1 - 0.00036 20.5 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase NAD_binding_3 PF03447.16 KEY69621.1 - 0.0055 17.4 0.0 0.038 14.6 0.0 2.1 3 0 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain CPT PF07931.12 KEY69621.1 - 0.0071 16.2 0.3 0.47 10.3 0.3 2.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 KEY69621.1 - 0.0097 16.2 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY69621.1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.20 KEY69621.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AvrPphF-ORF-2 PF09143.10 KEY69621.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 Pinin_SDK_memA PF04696.13 KEY69622.1 - 2.2e-34 118.3 17.0 2.2e-34 118.3 17.0 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF2951 PF11166.8 KEY69622.1 - 0.031 14.5 4.0 0.031 14.5 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) PHF5 PF03660.14 KEY69623.1 - 4e-52 174.8 10.4 4.6e-52 174.6 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KEY69623.1 - 0.69 7.7 7.8 0.71 7.7 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KEY69623.1 - 2.4 8.2 15.6 5.6 7.1 1.9 3.0 1 1 1 2 2 2 0 Double zinc ribbon Mem_trans PF03547.18 KEY69624.1 - 0.002 16.6 0.1 0.0033 15.9 0.1 1.3 1 0 0 1 1 1 1 Membrane transport protein Pex26 PF07163.12 KEY69624.1 - 0.0066 15.8 6.0 0.012 14.9 4.9 2.0 2 0 0 2 2 2 1 Pex26 protein Pro-rich_19 PF15455.6 KEY69624.1 - 0.011 14.9 2.9 0.018 14.2 2.9 1.2 1 0 0 1 1 1 0 Proline-rich 19 GAGA_bind PF06217.12 KEY69624.1 - 0.43 10.8 3.9 0.67 10.2 3.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1451 PF07295.11 KEY69624.1 - 1.7 8.7 11.6 3.1 7.8 11.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Haspin_kinase PF12330.8 KEY69625.1 - 3.3e-35 121.7 0.0 4.3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEY69625.1 - 0.096 12.6 1.4 0.26 11.2 1.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.14 KEY69626.1 - 2.2e-112 375.4 1.9 2.6e-112 375.2 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Thiamine_BP PF01910.17 KEY69627.1 - 4.2e-28 97.1 2.3 6.7e-28 96.5 2.3 1.3 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 KEY69627.1 - 0.0049 16.8 0.1 0.0061 16.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1335 PF07056.11 KEY69627.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1335) CDC37_N PF03234.14 KEY69629.1 - 1.3e-49 168.4 0.9 1.3e-49 168.4 0.9 3.0 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KEY69629.1 - 8.7e-40 135.3 0.2 2.4e-39 133.9 0.2 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KEY69629.1 - 2.6e-33 114.1 2.8 2.6e-33 114.1 2.8 2.5 2 1 0 2 2 2 1 Cdc37 C terminal domain Spectrin PF00435.21 KEY69629.1 - 0.46 11.0 6.8 0.18 12.3 1.0 2.7 2 0 0 2 2 2 0 Spectrin repeat BST2 PF16716.5 KEY69629.1 - 9.1 6.9 10.0 0.14 12.8 0.6 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 DUF3535 PF12054.8 KEY69630.1 - 3.2e-126 422.1 0.0 3.8e-125 418.6 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KEY69630.1 - 3.3e-66 223.4 0.0 7.1e-66 222.3 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY69630.1 - 5e-19 68.7 0.0 4.9e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 KEY69630.1 - 3.4e-18 64.2 3.2 0.002 18.3 0.0 7.9 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 KEY69630.1 - 6.1e-10 39.4 0.9 3.7e-05 24.0 0.1 5.8 5 1 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KEY69630.1 - 6.4e-09 36.3 0.7 0.32 11.6 0.0 4.8 3 1 0 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KEY69630.1 - 1.5e-05 25.4 5.9 7.2 7.2 0.0 7.1 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 KEY69630.1 - 0.0037 16.9 0.3 0.46 10.0 0.1 3.3 3 1 0 3 3 3 1 CLASP N terminal DEAD PF00270.29 KEY69630.1 - 0.0082 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase UME PF08064.13 KEY69630.1 - 0.065 13.2 1.7 25 4.9 0.0 4.2 4 1 1 5 5 5 0 UME (NUC010) domain SMC_N PF02463.19 KEY69631.1 - 1.8e-50 171.4 31.9 1.2e-49 168.7 31.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEY69631.1 - 1.3e-28 99.6 0.0 8.9e-28 96.9 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KEY69631.1 - 2e-15 57.4 39.4 8.4e-15 55.4 1.7 4.3 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 KEY69631.1 - 1.7e-09 37.9 0.1 1.6e-05 24.8 0.0 4.2 4 3 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY69631.1 - 3.5e-05 24.4 115.7 3.6e-05 24.4 47.5 7.7 3 2 2 5 5 3 2 AAA domain AAA_29 PF13555.6 KEY69631.1 - 0.0037 17.0 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DivIC PF04977.15 KEY69631.1 - 0.0087 15.8 3.3 0.0087 15.8 3.3 10.8 7 4 3 10 10 10 1 Septum formation initiator Laminin_II PF06009.12 KEY69631.1 - 0.011 15.7 1.9 0.011 15.7 1.9 8.2 4 2 3 8 8 8 0 Laminin Domain II DUF2935 PF11155.8 KEY69631.1 - 0.23 11.8 13.6 5.9 7.3 0.2 4.9 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) ABC_tran PF00005.27 KEY69631.1 - 0.66 10.5 0.0 0.66 10.5 0.0 6.9 3 2 1 4 4 2 0 ABC transporter PCI PF01399.27 KEY69631.1 - 2.1 8.9 7.9 0.25 11.9 0.7 3.1 3 0 0 3 3 3 0 PCI domain CCP_MauG PF03150.14 KEY69631.1 - 2.9 8.5 6.2 3.3 8.3 0.0 3.5 2 1 0 2 2 2 0 Di-haem cytochrome c peroxidase MRP-L46 PF11788.8 KEY69632.1 - 1.1e-28 100.3 0.0 2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PHD PF00628.29 KEY69633.1 - 2.2e-09 37.1 7.3 2.2e-09 37.1 7.3 2.7 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 KEY69633.1 - 3.2e-09 37.0 12.8 9.4e-08 32.2 0.2 3.0 4 0 0 4 4 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEY69633.1 - 1.5e-08 34.9 18.5 2.6e-07 30.9 0.4 3.5 3 1 0 3 3 3 2 Ring finger domain PHD_2 PF13831.6 KEY69633.1 - 4.7e-06 26.1 2.9 4.7e-06 26.1 2.9 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 KEY69633.1 - 2.3e-05 24.2 0.6 2.3e-05 24.2 0.6 2.8 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEY69633.1 - 9.2e-05 22.2 0.2 9.2e-05 22.2 0.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY69633.1 - 0.00036 20.4 0.6 0.00036 20.4 0.6 3.5 4 0 0 4 4 4 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KEY69633.1 - 0.00057 19.9 7.9 0.0092 16.0 0.4 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KEY69633.1 - 0.001 18.9 0.7 0.001 18.9 0.7 3.6 3 1 2 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KEY69633.1 - 0.0018 17.9 1.1 0.0018 17.9 1.1 2.8 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KEY69633.1 - 0.0021 18.0 6.2 0.0086 16.0 1.4 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KEY69633.1 - 0.0032 17.3 1.0 0.0032 17.3 1.0 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHF5 PF03660.14 KEY69633.1 - 0.023 14.9 0.6 0.023 14.9 0.6 2.1 3 0 0 3 3 2 0 PHF5-like protein zf-PHD-like PF15446.6 KEY69633.1 - 0.025 14.2 0.5 0.025 14.2 0.5 2.4 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 KEY69633.1 - 0.077 13.0 8.6 1.1 9.2 2.9 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RecR PF02132.15 KEY69633.1 - 0.17 11.5 8.5 2.7 7.7 0.4 3.6 3 0 0 3 3 3 0 RecR protein PHD_3 PF13922.6 KEY69633.1 - 0.55 10.7 6.3 4.7 7.7 0.8 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF1644 PF07800.12 KEY69633.1 - 2.4 8.2 6.8 37 4.3 2.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) CCDC24 PF15669.5 KEY69633.1 - 5.5 6.8 9.0 0.15 11.9 1.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-RING_6 PF14835.6 KEY69633.1 - 7.5 6.5 7.9 0.16 11.8 0.3 2.1 2 1 1 3 3 1 0 zf-RING of BARD1-type protein Ribosomal_L37ae PF01780.19 KEY69634.1 - 7.7e-39 131.7 10.1 8.6e-39 131.5 10.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KEY69634.1 - 0.002 18.0 3.8 0.0034 17.3 3.8 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.11 KEY69634.1 - 0.0043 16.6 0.5 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-BED PF02892.15 KEY69634.1 - 0.012 15.6 5.3 0.037 14.1 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger DUF1451 PF07295.11 KEY69634.1 - 0.015 15.3 0.9 0.021 14.9 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-RING_13 PF17977.1 KEY69634.1 - 0.026 14.7 1.6 0.037 14.2 1.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 KEY69634.1 - 2.3 8.8 6.7 0.57 10.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Sacchrp_dh_NADP PF03435.18 KEY69635.1 - 3.3e-17 63.0 0.0 4.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY69635.1 - 0.0073 16.7 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain MerE PF05052.12 KEY69635.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 MerE protein KR PF08659.10 KEY69635.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 KR domain Shikimate_DH PF01488.20 KEY69635.1 - 0.2 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF155 PF02582.14 KEY69636.1 - 2e-52 177.9 0.3 2.9e-52 177.3 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.19 KEY69637.1 - 5.2e-07 30.0 5.2 6.4e-07 29.7 3.7 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box DUF2443 PF10398.9 KEY69637.1 - 0.1 12.7 0.8 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Hamartin PF04388.12 KEY69637.1 - 2.1 6.9 8.6 2.3 6.8 8.6 1.1 1 0 0 1 1 1 0 Hamartin protein Cpn60_TCP1 PF00118.24 KEY69638.1 - 2.6e-150 501.3 11.4 3e-150 501.1 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.9 KEY69638.1 - 0.019 14.6 0.1 5 6.7 0.0 2.8 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) PrpR_N PF06506.11 KEY69638.1 - 0.026 14.1 0.2 0.1 12.2 0.0 2.2 3 0 0 3 3 3 0 Propionate catabolism activator EAL PF00563.20 KEY69638.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 EAL domain PH_10 PF15411.6 KEY69639.1 - 7.6e-30 103.7 0.2 1.3e-29 103.0 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KEY69639.1 - 1.7e-14 54.4 0.0 3.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEY69639.1 - 2.7e-10 40.4 0.2 1.2e-09 38.3 0.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KEY69639.1 - 0.00059 20.1 5.7 0.0011 19.3 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KEY69639.1 - 0.0021 18.0 5.6 0.0035 17.3 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEY69639.1 - 0.013 15.3 4.8 0.026 14.3 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY69639.1 - 0.046 13.6 5.5 0.087 12.7 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ScsC_N PF18312.1 KEY69639.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Zn_ribbon_17 PF17120.5 KEY69639.1 - 0.067 12.8 7.0 0.016 14.8 3.4 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KEY69639.1 - 0.094 13.0 2.9 0.21 11.9 2.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KEY69639.1 - 0.099 13.0 4.6 0.18 12.1 4.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KEY69639.1 - 0.1 12.4 4.2 0.21 11.4 4.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger CCDC24 PF15669.5 KEY69639.1 - 0.16 11.8 0.9 0.55 10.1 0.9 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family PH PF00169.29 KEY69639.1 - 0.17 12.4 0.0 0.41 11.2 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.11 KEY69639.1 - 0.19 11.8 0.6 0.57 10.3 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 KEY69639.1 - 1.2 9.2 4.3 2.6 8.2 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger DUF4244 PF14029.6 KEY69640.1 - 0.016 14.7 0.4 0.038 13.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) T4SS_TraI PF16932.5 KEY69641.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer U3_snoRNA_assoc PF08297.11 KEY69642.1 - 1e-13 51.7 1.0 1e-13 51.7 1.0 3.9 3 1 0 3 3 3 1 U3 snoRNA associated Mobilization_B PF17511.2 KEY69642.1 - 0.93 9.9 13.9 2 8.8 13.9 1.5 1 0 0 1 1 1 0 Mobilization protein B GREB1 PF15782.5 KEY69642.1 - 9.7 3.2 20.0 12 2.8 20.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ANAPC3 PF12895.7 KEY69643.1 - 8.9e-07 29.1 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KEY69643.1 - 1.9e-06 28.3 0.7 5e-06 26.9 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY69643.1 - 9.7e-05 22.2 0.1 0.29 11.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY69643.1 - 0.00062 19.6 0.2 2.3 8.2 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY69643.1 - 0.0011 19.0 2.6 1.2 9.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY69643.1 - 0.0016 18.7 3.2 0.0054 17.0 0.6 2.7 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY69643.1 - 0.0055 16.6 0.9 0.075 13.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY69643.1 - 0.0058 16.0 0.8 0.0095 15.3 0.8 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KEY69643.1 - 0.012 16.4 7.0 3.4 8.7 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY69643.1 - 0.019 14.8 0.2 4.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KEY69643.1 - 0.036 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 KEY69643.1 - 0.061 14.0 0.0 0.91 10.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY69643.1 - 0.4 11.4 3.5 0.82 10.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_7 PF03441.14 KEY69644.1 - 2e-71 239.7 0.2 2.9e-71 239.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KEY69644.1 - 5.6e-33 114.3 0.0 1.2e-32 113.2 0.0 1.5 2 0 0 2 2 2 1 DNA photolyase Trypan_PARP PF05887.11 KEY69644.1 - 0.013 15.4 1.8 0.026 14.5 1.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p12I PF12233.8 KEY69644.1 - 0.22 12.0 1.3 25 5.4 0.1 2.6 3 0 0 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein UBA PF00627.31 KEY69646.1 - 8.9e-26 89.4 9.5 1.4e-13 50.4 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KEY69646.1 - 3.8e-24 84.2 14.2 6.7e-24 83.4 14.2 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KEY69646.1 - 1.4e-11 44.0 0.1 3.5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family UBA_3 PF09288.10 KEY69646.1 - 0.0019 17.9 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.6 KEY69646.1 - 0.025 15.2 0.6 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 MCM N-terminal domain Rad60-SLD PF11976.8 KEY69646.1 - 0.043 13.6 0.2 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KEY69646.1 - 0.098 12.4 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 CUE domain WIYLD PF10440.9 KEY69646.1 - 0.2 11.5 0.8 2 8.3 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_7 PF15963.5 KEY69647.1 - 9.5e-23 79.9 2.1 1.1e-22 79.7 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KEY69647.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY69647.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.11 KEY69648.1 - 2.2e-28 98.2 8.6 2.2e-28 98.2 8.6 6.8 5 2 1 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KEY69648.1 - 1.3e-08 34.5 7.8 2.1e-08 33.9 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY69648.1 - 3.6e-08 33.2 11.1 6.2e-08 32.4 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY69648.1 - 4e-08 33.0 7.1 6.6e-08 32.3 7.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEY69648.1 - 3.2e-07 30.1 8.9 5.6e-07 29.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY69648.1 - 8e-07 29.0 5.7 1.5e-06 28.1 5.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEY69648.1 - 3.1e-06 27.4 8.4 5.1e-06 26.7 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KEY69648.1 - 7.2e-06 25.9 10.1 1.2e-05 25.2 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain JIP_LZII PF16471.5 KEY69648.1 - 0.0032 17.6 1.7 0.0032 17.6 1.7 6.5 6 1 0 6 6 6 2 JNK-interacting protein leucine zipper II zf-C3HC4_4 PF15227.6 KEY69648.1 - 0.0096 16.1 6.4 0.018 15.2 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DivIC PF04977.15 KEY69648.1 - 0.02 14.6 1.6 0.02 14.6 1.6 9.0 4 2 3 9 9 9 0 Septum formation initiator zf-RING_4 PF14570.6 KEY69648.1 - 0.089 12.6 7.3 0.37 10.6 7.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MLD PF11647.8 KEY69648.1 - 0.094 13.0 3.2 0.25 11.6 0.3 3.2 3 0 0 3 3 2 0 Membrane Localization Domain Retrotrans_gag PF03732.17 KEY69648.1 - 0.21 11.9 12.1 0.31 11.3 0.3 4.5 3 2 0 3 3 3 0 Retrotransposon gag protein zf-RING_6 PF14835.6 KEY69648.1 - 0.22 11.4 2.2 0.53 10.2 2.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 KEY69648.1 - 0.4 10.8 4.0 1.4 9.1 3.6 2.1 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 KEY69648.1 - 0.55 10.6 8.1 8.4 6.8 8.1 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain VGPC1_C PF16799.5 KEY69648.1 - 0.58 10.2 5.3 11 6.1 0.1 3.6 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF1272 PF06906.11 KEY69648.1 - 1.2 9.3 6.2 2.7 8.2 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KEY69648.1 - 1.6 8.6 4.2 3.5 7.5 4.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger FYVE PF01363.21 KEY69648.1 - 1.7 8.9 11.5 14 5.9 11.4 2.3 1 1 1 2 2 2 0 FYVE zinc finger DUF1492 PF07374.11 KEY69648.1 - 1.9 8.7 7.0 5.5 7.2 0.8 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) DZR PF12773.7 KEY69648.1 - 3.3 7.8 6.5 6.3 6.9 6.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon SARAF PF06682.12 KEY69649.1 - 5.9e-103 345.0 2.6 7.1e-103 344.7 2.6 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis ABC_membrane PF00664.23 KEY69651.1 - 5.7e-103 344.3 39.0 1.2e-51 176.0 17.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY69651.1 - 9.9e-68 226.9 0.0 1.4e-33 116.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY69651.1 - 2.2e-13 50.2 0.0 0.00032 20.2 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEY69651.1 - 2.5e-07 30.8 0.1 0.032 14.1 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KEY69651.1 - 5.8e-07 29.2 0.9 0.0023 17.6 0.2 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY69651.1 - 8.7e-06 26.2 7.7 0.0084 16.5 0.1 3.9 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KEY69651.1 - 1.3e-05 24.2 3.4 0.059 12.2 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KEY69651.1 - 1.5e-05 24.9 0.1 0.056 13.2 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 KEY69651.1 - 0.00018 21.2 0.1 0.35 10.4 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KEY69651.1 - 0.0003 21.2 2.2 4.8 7.6 0.1 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY69651.1 - 0.00046 20.5 2.7 0.53 10.6 0.1 3.8 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY69651.1 - 0.0022 17.8 2.7 2.9 7.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain G-alpha PF00503.20 KEY69651.1 - 0.0032 16.7 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KEY69651.1 - 0.0043 16.9 2.2 3.4 7.4 0.1 3.5 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KEY69651.1 - 0.0075 15.6 0.0 3 7.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KEY69651.1 - 0.0082 16.1 0.8 9.2 6.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEY69651.1 - 0.013 15.0 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KEY69651.1 - 0.015 15.5 0.0 11 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain Cu_bind_CorA PF18252.1 KEY69651.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Copper(I)-binding protein CorA DUF87 PF01935.17 KEY69651.1 - 0.021 14.9 3.3 3.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KEY69651.1 - 0.027 15.0 0.0 9.8 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEY69651.1 - 0.04 13.1 0.1 13 4.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KEY69651.1 - 0.091 13.3 2.6 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KEY69651.1 - 0.11 12.2 0.0 8.9 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEY69651.1 - 0.12 12.6 5.3 0.58 10.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 KEY69651.1 - 0.13 12.5 7.2 5 7.4 0.2 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KEY69651.1 - 0.16 11.9 0.1 3.4 7.5 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 KEY69651.1 - 0.16 11.9 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KEY69651.1 - 0.18 12.2 0.1 21 5.6 0.0 3.1 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KEY69651.1 - 0.21 11.6 0.4 20 5.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KEY69651.1 - 0.32 11.4 2.1 32 5.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain PSI_integrin PF17205.3 KEY69652.1 - 0.063 13.0 0.2 0.19 11.5 0.2 1.8 1 0 0 1 1 1 0 Integrin plexin domain QWRF PF04484.12 KEY69652.1 - 0.22 11.2 1.8 0.36 10.5 1.8 1.3 1 0 0 1 1 1 0 QWRF family Sporozoite_P67 PF05642.11 KEY69652.1 - 0.34 8.9 5.0 0.48 8.5 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KEY69652.1 - 0.45 8.8 4.5 0.61 8.3 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Cupin_5 PF06172.11 KEY69653.1 - 1.6e-43 148.2 0.0 1.9e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF3425 PF11905.8 KEY69654.1 - 4.7e-22 78.3 1.3 8.8e-22 77.4 0.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KEY69654.1 - 0.05 13.7 11.4 0.14 12.3 11.4 1.8 1 1 0 1 1 1 0 bZIP transcription factor TetR_C_22 PF17928.1 KEY69654.1 - 0.051 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain E1-E2_ATPase PF00122.20 KEY69656.1 - 3.4e-48 163.6 6.0 3.4e-48 163.6 6.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEY69656.1 - 6e-16 59.4 0.0 2.2e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY69656.1 - 1.2e-10 40.9 0.0 2.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY69656.1 - 0.0027 17.5 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY69656.1 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) CTD_bind PF04818.13 KEY69657.1 - 7.5e-09 36.3 0.0 1.4e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KEY69657.1 - 4.8e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0020 PF01170.18 KEY69657.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Citrate_synt PF00285.21 KEY69658.1 - 7.2e-100 334.5 0.0 9.3e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KEY69658.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 KEY69659.1 - 2.9e-27 94.4 4.2 5.9e-12 45.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MBD PF01429.19 KEY69659.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyl-CpG binding domain WD40 PF00400.32 KEY69660.1 - 9e-05 23.2 15.2 0.17 12.8 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 KEY69660.1 - 0.029 13.0 0.1 13 4.3 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 AMP-binding PF00501.28 KEY69661.1 - 1e-85 287.9 0.0 1.2e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.23 KEY69662.1 - 4.3e-14 52.7 14.4 5.4e-14 52.4 14.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 KEY69663.1 - 6.1e-144 479.3 0.0 9.8e-144 478.6 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEY69663.1 - 5e-10 39.2 0.2 9.2e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KEY69663.1 - 2.6e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEY69663.1 - 1.4e-07 30.8 0.4 2.3e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEY69663.1 - 3.9e-06 26.4 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KEY69663.1 - 0.00075 18.1 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KEY69663.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2012 PF09430.10 KEY69664.1 - 7.4e-25 87.4 0.0 9.7e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KEY69664.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein WW PF00397.26 KEY69665.1 - 9.5e-10 38.4 6.1 1.8e-09 37.5 6.1 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KEY69665.1 - 0.001 19.2 21.1 0.001 19.2 21.1 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Choline_transpo PF04515.12 KEY69666.1 - 9.8e-33 113.7 16.2 9.8e-33 113.7 16.2 2.6 1 1 2 3 3 3 1 Plasma-membrane choline transporter DUF1993 PF09351.10 KEY69667.1 - 1.6e-47 161.6 0.0 1.8e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Ras PF00071.22 KEY69668.1 - 6.3e-51 172.2 0.0 9.8e-40 135.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEY69668.1 - 8.1e-29 100.3 0.0 3.1e-18 66.1 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY69668.1 - 3.2e-12 46.3 0.0 1e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY69668.1 - 7.9e-07 28.8 0.0 6.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEY69668.1 - 2.2e-06 27.2 0.0 4.2e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY69668.1 - 5.6e-05 23.2 0.0 0.00024 21.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY69668.1 - 0.00093 19.1 0.2 0.92 9.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KEY69668.1 - 0.024 14.4 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KEY69668.1 - 0.093 13.0 0.8 0.71 10.1 0.4 2.4 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KEY69668.1 - 0.18 12.3 1.2 0.8 10.2 1.2 2.1 1 1 0 1 1 1 0 ABC transporter PMT PF02366.18 KEY69669.1 - 1.3e-87 293.5 13.2 1.3e-87 293.5 13.2 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEY69669.1 - 1.3e-65 220.7 15.1 1.3e-65 220.7 15.1 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEY69669.1 - 6.6e-38 130.4 0.8 1e-37 129.8 0.8 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KEY69669.1 - 0.049 13.4 0.5 0.049 13.4 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) zf-CHY PF05495.12 KEY69670.1 - 1.8e-20 73.2 20.4 1.8e-20 73.2 20.4 3.4 2 1 1 3 3 1 1 CHY zinc finger zinc_ribbon_6 PF14599.6 KEY69670.1 - 3.2e-16 59.1 0.0 3.2e-16 59.1 0.0 4.0 4 1 1 5 5 2 1 Zinc-ribbon zf-RING_2 PF13639.6 KEY69670.1 - 8.9e-08 32.3 9.8 8.9e-08 32.3 9.8 4.7 2 1 2 4 4 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEY69670.1 - 1.1e-06 28.6 3.5 1.1e-06 28.6 3.5 3.8 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEY69670.1 - 2.3e-06 27.4 8.3 2.3e-06 27.4 8.3 5.9 3 2 2 5 5 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEY69670.1 - 5.3e-06 26.2 8.3 5.3e-06 26.2 8.3 3.8 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY69670.1 - 1.6e-05 24.7 6.2 1.6e-05 24.7 6.2 4.7 2 1 2 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY69670.1 - 2.5e-05 24.0 8.0 2.5e-05 24.0 8.0 5.2 2 1 4 6 6 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEY69670.1 - 0.0041 16.8 2.1 0.0041 16.8 2.1 3.8 3 0 0 3 3 3 1 RING-like zinc finger ACC_epsilon PF13822.6 KEY69670.1 - 0.16 12.7 2.3 0.52 11.0 2.3 1.9 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit CENP-B_dimeris PF09026.10 KEY69670.1 - 1.1 9.7 7.7 2.3 8.6 7.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MOZART1 PF12554.8 KEY69671.1 - 1.7e-25 88.5 0.8 2.2e-25 88.2 0.8 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Spindle_Spc25 PF08234.12 KEY69672.1 - 4.3e-25 87.7 0.1 1.2e-24 86.3 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF1843 PF08898.10 KEY69672.1 - 0.023 15.2 0.2 0.082 13.4 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) V_ATPase_I PF01496.19 KEY69672.1 - 0.36 8.7 4.9 0.43 8.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KEY69672.1 - 0.79 8.7 8.7 1.2 8.2 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KEY69672.1 - 1.5 8.0 9.0 1.9 7.6 9.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.6 KEY69672.1 - 9.1 6.4 9.9 29 4.7 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Rrn6 PF10214.9 KEY69673.1 - 2.3e-88 297.7 0.0 3.1e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor PITH PF06201.13 KEY69673.1 - 3.5e-41 140.9 0.0 5.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.22 KEY69674.1 - 1.9e-16 60.0 1.7 3.8e-14 52.5 0.8 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KEY69675.1 - 2.3e-37 127.3 0.0 3e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2157 PF09925.9 KEY69676.1 - 0.15 11.8 2.7 0.42 10.4 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Ank_2 PF12796.7 KEY69677.1 - 1.2e-29 102.7 3.8 1.2e-10 41.8 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY69677.1 - 2.9e-26 91.5 4.8 5.1e-09 36.5 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69677.1 - 7.2e-17 59.8 5.6 0.0036 17.7 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KEY69677.1 - 3.2e-14 52.8 11.2 0.0081 16.5 0.1 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) SPX PF03105.19 KEY69677.1 - 5.7e-13 49.5 20.2 2e-09 37.9 1.3 4.8 2 2 2 4 4 4 3 SPX domain CUE PF02845.16 KEY69677.1 - 8.6e-13 47.7 0.0 2.4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain Ank PF00023.30 KEY69677.1 - 2.3e-10 40.4 12.7 0.089 13.3 0.0 6.7 5 1 1 6 6 6 3 Ankyrin repeat GDPD PF03009.17 KEY69677.1 - 5.2e-09 36.2 0.0 2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RVP PF00077.20 KEY69677.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease HA2 PF04408.23 KEY69678.1 - 3.6e-18 65.8 0.1 1.1e-17 64.3 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY69678.1 - 3.3e-13 49.8 0.0 7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEY69678.1 - 1e-12 48.4 0.0 2.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEY69678.1 - 0.00019 21.7 0.0 0.0005 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY69678.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KEY69678.1 - 0.0046 16.7 1.7 0.026 14.3 0.8 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KEY69678.1 - 0.015 15.7 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEY69678.1 - 0.11 12.1 0.1 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KEY69678.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KEY69678.1 - 0.29 11.6 1.2 0.74 10.3 1.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2615 PF11027.8 KEY69679.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) SKG6 PF08693.10 KEY69680.1 - 2.3e-09 36.5 3.0 6.1e-09 35.2 3.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KEY69680.1 - 0.00047 20.1 0.1 0.00047 20.1 0.1 2.9 2 1 1 3 3 3 1 TMEM154 protein family CcmD PF04995.14 KEY69680.1 - 0.0046 17.0 0.8 0.0077 16.3 0.8 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4448 PF14610.6 KEY69680.1 - 0.039 13.7 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 KEY69680.1 - 0.057 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2681 PF10883.8 KEY69680.1 - 0.073 13.5 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CD34_antigen PF06365.12 KEY69680.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family COesterase PF00135.28 KEY69681.1 - 8.2e-62 209.7 0.0 1.1e-61 209.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY69681.1 - 3.6e-07 30.2 2.2 6.3e-07 29.5 1.3 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold PAP1 PF08601.10 KEY69682.1 - 0.34 10.6 4.4 0.14 11.9 0.8 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 DASH_Dad2 PF08654.10 KEY69683.1 - 2.2e-32 111.4 1.1 3.5e-32 110.8 1.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KEY69683.1 - 0.021 14.6 0.1 0.037 13.8 0.1 1.5 1 1 0 1 1 1 0 DASH complex subunit Duo1 SLX9 PF15341.6 KEY69683.1 - 0.021 15.2 0.6 0.025 15.0 0.6 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2555 PF10742.9 KEY69683.1 - 0.05 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Seryl_tRNA_N PF02403.22 KEY69683.1 - 0.068 13.4 0.2 0.068 13.4 0.2 1.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rogdi_lz PF10259.9 KEY69683.1 - 0.096 12.1 2.1 0.11 11.9 2.1 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Shugoshin_N PF07558.11 KEY69684.1 - 2.6e-15 56.0 7.5 9.9e-15 54.1 7.5 2.1 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KEY69684.1 - 1.2e-10 40.9 6.6 1.2e-10 40.9 6.6 3.1 3 0 0 3 3 3 1 Shugoshin C terminus Metallophos_2 PF12850.7 KEY69685.1 - 3.6e-12 46.8 0.0 4.7e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KEY69685.1 - 0.081 13.4 0.0 2 8.9 0.0 2.1 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase NUC173 PF08161.12 KEY69686.1 - 5.9e-80 267.7 2.7 1.9e-77 259.5 0.2 3.4 4 0 0 4 4 4 2 NUC173 domain Vac14_Fab1_bd PF12755.7 KEY69686.1 - 0.0094 16.5 0.3 6.8 7.4 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KEY69686.1 - 0.01 16.2 0.4 14 6.1 0.1 4.6 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 KEY69686.1 - 0.04 14.2 5.6 4.8 7.7 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat DUF2293 PF10056.9 KEY69687.1 - 3.5e-33 113.7 0.1 9.1e-33 112.4 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) NinG PF05766.12 KEY69687.1 - 0.051 13.5 2.0 0.088 12.7 2.0 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein bZIP_1 PF00170.21 KEY69688.1 - 3.5e-09 36.6 11.1 1.1e-08 35.1 11.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY69688.1 - 0.0017 18.4 11.1 0.0017 18.4 11.1 2.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF4407 PF14362.6 KEY69688.1 - 1.1 8.6 20.1 2.1 7.7 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KEY69688.1 - 8.5 6.2 25.6 0.055 13.2 1.3 3.0 3 0 0 3 3 3 0 Septum formation initiator HET PF06985.11 KEY69689.1 - 5.2e-36 124.2 0.2 8.4e-36 123.5 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_2 PF00328.22 KEY69690.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) JmjC PF02373.22 KEY69691.1 - 2.3e-38 131.1 0.1 6.3e-38 129.7 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KEY69691.1 - 1.1e-20 73.9 2.3 2.2e-20 72.9 2.3 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KEY69691.1 - 1.5e-19 70.1 7.3 1.8e-19 69.8 2.9 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KEY69691.1 - 4.1e-14 52.2 0.4 2.1e-13 50.0 0.7 2.1 2 0 0 2 2 2 1 jmjN domain Pkinase PF00069.25 KEY69692.1 - 1.8e-36 125.9 0.0 2.5e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69692.1 - 2.9e-23 82.5 0.0 4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY69692.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY69692.1 - 0.0053 16.1 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IL3Ra_N PF18611.1 KEY69692.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain Aminotran_1_2 PF00155.21 KEY69693.1 - 4.9e-67 226.6 0.0 5.6e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEY69693.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEY69693.1 - 0.0042 15.7 0.1 0.0088 14.6 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEY69693.1 - 0.035 13.4 0.1 0.073 12.4 0.1 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEY69693.1 - 0.081 11.9 0.0 0.17 10.8 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Ald_Xan_dh_C2 PF02738.18 KEY69694.1 - 4.6e-207 688.8 0.2 6.7e-207 688.3 0.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KEY69694.1 - 5.5e-49 166.2 0.0 1.2e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KEY69694.1 - 3.3e-32 111.1 0.3 8.6e-32 109.8 0.3 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KEY69694.1 - 2.6e-30 104.6 0.2 9.7e-30 102.8 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KEY69694.1 - 2.7e-30 104.2 0.0 5.9e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KEY69694.1 - 3.8e-07 30.0 1.7 6e-07 29.3 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.16 KEY69694.1 - 0.013 15.5 0.1 5 7.3 0.1 3.3 3 0 0 3 3 3 0 Sigma-70 region 3 PAS PF00989.25 KEY69695.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold SPO22 PF08631.10 KEY69696.1 - 1.3e-58 198.7 3.0 1.4e-56 192.1 0.0 3.6 4 1 1 5 5 5 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KEY69696.1 - 0.0017 18.6 11.4 0.0037 17.5 0.0 3.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY69696.1 - 0.022 15.4 3.8 0.05 14.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KEY69697.1 - 6.9e-25 87.6 0.0 1.4e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69697.1 - 6.9e-08 32.5 13.7 1.5e-07 31.4 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KEY69697.1 - 0.023 13.8 0.8 0.033 13.3 0.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ufd2P_core PF10408.9 KEY69698.1 - 4.3e-208 692.9 9.2 5.5e-208 692.6 9.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KEY69698.1 - 6.3e-23 80.8 2.0 2.2e-22 79.0 2.0 2.0 1 0 0 1 1 1 1 U-box domain CCDC-167 PF15188.6 KEY69698.1 - 6 7.3 7.7 0.69 10.3 1.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-TRAF PF02176.18 KEY69699.1 - 8.5e-13 48.8 23.5 8.5e-09 36.0 3.0 3.6 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4 PF00097.25 KEY69699.1 - 1.6e-08 34.2 8.6 1.6e-08 34.2 8.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY69699.1 - 1.1e-07 31.5 9.0 1.1e-07 31.5 9.0 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY69699.1 - 2.2e-07 30.6 5.8 2.2e-07 30.6 5.8 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY69699.1 - 3.5e-07 30.3 9.9 3.5e-07 30.3 9.9 2.9 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KEY69699.1 - 3.8e-07 30.0 8.7 3.8e-07 30.0 8.7 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEY69699.1 - 7.6e-06 26.2 9.3 7.6e-06 26.2 9.3 3.3 2 1 1 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KEY69699.1 - 1.6e-05 24.8 6.1 1.6e-05 24.8 6.1 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-Nse PF11789.8 KEY69699.1 - 0.0036 17.1 4.5 0.0036 17.1 4.5 2.3 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KEY69699.1 - 0.013 15.7 1.3 0.055 13.7 0.3 2.3 2 0 0 2 2 2 0 U-box domain zf-ANAPC11 PF12861.7 KEY69699.1 - 0.019 15.0 2.5 0.019 15.0 2.5 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AUDH_Cupin PF18637.1 KEY69699.1 - 0.094 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain zf-RING_6 PF14835.6 KEY69699.1 - 0.14 12.0 8.8 0.062 13.2 5.5 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 KEY69699.1 - 1.6 9.2 25.2 6.4 7.3 0.3 3.6 1 1 2 3 3 3 0 TRAF-like zinc-finger Abhydrolase_3 PF07859.13 KEY69700.1 - 3e-33 115.5 0.0 8.2e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold RNA_pol_Rpc4 PF05132.14 KEY69700.1 - 3.3 8.1 5.8 0.65 10.4 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase III RPC4 Pyridoxal_deC PF00282.19 KEY69701.1 - 1.6e-73 247.6 0.0 2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.21 KEY69702.1 - 8.8e-112 373.7 0.0 1.1e-111 373.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEY69702.1 - 0.00051 19.3 0.0 0.0014 17.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II ATG27 PF09451.10 KEY69703.1 - 7.7e-99 330.8 0.1 9.5e-99 330.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KEY69703.1 - 0.001 19.1 0.2 3 7.9 0.0 3.1 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Spt20 PF12090.8 KEY69704.1 - 1.5e-41 142.5 0.0 1.5e-41 142.5 0.0 6.9 5 3 0 5 5 5 1 Spt20 family Hexapep PF00132.24 KEY69706.1 - 5.6e-05 22.7 4.2 0.024 14.4 1.2 3.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KEY69706.1 - 9.3e-05 21.5 0.4 0.00015 20.8 0.4 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KEY69706.1 - 0.00018 19.8 0.3 0.00026 19.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KEY69706.1 - 0.00029 21.2 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KEY69706.1 - 0.1 12.4 5.7 1.2 8.9 0.3 3.0 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pex14_N PF04695.13 KEY69706.1 - 3.7 8.2 5.5 3.9 8.1 1.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2_4 PF13894.6 KEY69707.1 - 0.00016 22.2 8.9 0.18 12.7 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY69707.1 - 0.00074 19.8 16.8 0.0026 18.1 4.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KEY69707.1 - 0.015 15.6 1.2 0.079 13.3 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KEY69707.1 - 0.016 15.8 0.6 0.051 14.2 0.6 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain OrsD PF12013.8 KEY69707.1 - 0.16 12.5 3.2 0.31 11.5 2.6 1.8 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D LRR_4 PF12799.7 KEY69708.1 - 7e-06 26.3 5.8 0.17 12.3 2.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEY69708.1 - 2.3e-05 24.1 2.7 0.011 15.7 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KEY69708.1 - 0.0021 17.8 6.8 1.6 8.6 0.1 4.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KEY69708.1 - 0.089 13.4 2.1 22 6.1 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Glyco_hydro_35 PF01301.19 KEY69709.1 - 1.4e-89 300.9 1.2 2.4e-89 300.1 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KEY69709.1 - 1.8e-56 190.8 0.2 2.8e-56 190.2 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KEY69709.1 - 1.4e-52 177.1 0.4 6.4e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KEY69709.1 - 5.6e-19 67.5 0.1 3.6e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KEY69709.1 - 4.7e-07 29.5 0.9 1.5e-06 27.9 0.2 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SPX PF03105.19 KEY69711.1 - 3 7.7 9.0 3.6 7.4 9.0 1.1 1 0 0 1 1 1 0 SPX domain F-box PF00646.33 KEY69712.1 - 3.6e-09 36.3 0.1 8.1e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY69712.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Tmemb_14 PF03647.13 KEY69712.1 - 0.0067 17.1 0.9 0.024 15.4 0.3 2.0 1 1 1 2 2 2 1 Transmembrane proteins 14C 7TM_GPCR_Srb PF02175.16 KEY69712.1 - 0.037 13.8 0.2 0.08 12.7 0.2 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb CarbpepA_inh PF02977.15 KEY69712.1 - 5.7 6.8 9.0 0.48 10.2 2.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Abhydrolase_1 PF00561.20 KEY69713.1 - 3.7e-12 46.5 0.0 6.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY69713.1 - 1.2e-11 45.6 1.0 3.4e-11 44.2 1.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY69713.1 - 2.4e-09 36.8 0.0 3e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY69713.1 - 1.4e-05 23.9 0.0 6.4e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Ndr family EthD PF07110.11 KEY69713.1 - 1.8e-05 25.8 0.7 0.02 16.1 0.1 2.9 2 0 0 2 2 2 2 EthD domain Esterase PF00756.20 KEY69713.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Zn_clus PF00172.18 KEY69714.1 - 6e-06 26.3 8.5 9.9e-06 25.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDH-cyt PF16010.5 KEY69715.1 - 1.2e-47 161.9 0.6 1.4e-47 161.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase E1-E2_ATPase PF00122.20 KEY69719.1 - 1.4e-37 129.0 21.8 9.1e-31 106.8 0.2 4.0 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY69719.1 - 4e-20 72.3 6.2 4e-20 72.3 6.2 3.1 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY69719.1 - 4.9e-18 66.2 0.0 4.2e-17 63.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY69719.1 - 5.7e-16 58.4 0.0 1.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEY69719.1 - 3.6e-15 55.4 0.0 1.2e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEY69719.1 - 0.0015 18.4 0.4 0.0054 16.5 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KEY69719.1 - 0.004 17.1 1.1 0.0097 15.8 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) PI3K_C2 PF00792.24 KEY69719.1 - 0.046 13.6 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 ITAM_Cys-rich PF10538.9 KEY69719.1 - 0.11 12.2 0.3 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif FAD_binding_3 PF01494.19 KEY69720.1 - 1.3e-15 57.5 0.0 7.9e-15 55.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEY69720.1 - 0.00039 20.9 0.0 0.0057 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY69720.1 - 0.0019 17.8 1.5 0.073 12.6 2.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY69720.1 - 0.0057 15.9 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEY69720.1 - 0.0066 16.1 0.1 0.018 14.7 0.2 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KEY69720.1 - 0.015 14.4 1.3 0.025 13.7 1.3 1.3 1 0 0 1 1 1 0 FAD binding domain Rossmann-like PF10727.9 KEY69720.1 - 0.057 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_8 PF13450.6 KEY69720.1 - 0.096 12.9 0.4 0.23 11.7 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SHNi-TPR PF10516.9 KEY69720.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR Pyr_redox_3 PF13738.6 KEY69720.1 - 0.15 11.3 0.0 2 7.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KGG PF10685.9 KEY69721.1 - 1.7e-25 88.5 14.5 2e-10 40.6 0.5 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Hemerythrin PF01814.23 KEY69722.1 - 8.4e-10 39.4 1.3 8.4e-10 39.4 1.3 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.25 KEY69723.1 - 3.8e-17 62.4 0.0 8.5e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69723.1 - 4.7e-11 42.7 0.0 4.8e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_4 PF13637.6 KEY69724.1 - 3e-15 56.4 4.6 1.8e-05 25.2 0.1 6.4 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY69724.1 - 2.7e-14 53.5 0.8 7.6e-10 39.2 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEY69724.1 - 9.5e-12 44.8 3.9 0.0017 18.7 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEY69724.1 - 3.4e-09 36.8 7.7 0.00014 22.1 0.2 4.9 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69724.1 - 7e-09 35.2 2.4 0.0012 19.2 0.0 5.9 6 1 0 6 6 6 1 Ankyrin repeat Mito_carr PF00153.27 KEY69727.1 - 9.9e-43 144.0 7.7 7.3e-16 57.9 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.19 KEY69728.1 - 1.6e-32 112.7 0.0 4.9e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY69728.1 - 1.8e-12 47.2 0.0 1.6e-09 37.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY69728.1 - 1.3e-06 27.9 0.1 1.2e-05 24.7 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY69728.1 - 6e-06 25.7 0.0 1.8e-05 24.2 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY69728.1 - 0.0029 17.6 0.0 0.02 14.9 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY69728.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY69728.1 - 0.026 14.1 0.1 2.1 7.8 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Csd3_N PF18059.1 KEY69730.1 - 0.14 12.6 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Csd3 N-terminal MFS_1 PF07690.16 KEY69731.1 - 3.8e-15 55.7 31.9 3.8e-15 55.7 31.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY69731.1 - 5.9e-05 22.1 7.1 5.9e-05 22.1 7.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.6 KEY69731.1 - 0.53 10.6 2.9 1.5 9.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) SDA1 PF05285.12 KEY69732.1 - 3.4e-90 303.0 56.4 1.1e-89 301.3 47.1 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KEY69732.1 - 4.2e-22 78.2 1.8 5.5e-22 77.8 0.1 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Gcd10p PF04189.13 KEY69733.1 - 5.9e-112 373.6 0.0 7.8e-112 373.3 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family bPH_6 PF10756.9 KEY69733.1 - 0.027 14.5 1.3 9.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Bacterial PH domain P21-Arc PF04062.14 KEY69734.1 - 1e-73 247.1 0.0 1.2e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit BES1_N PF05687.13 KEY69735.1 - 0.19 12.1 1.4 1 9.7 0.3 2.2 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal NmrA PF05368.13 KEY69736.1 - 6.8e-81 271.2 0.0 8.4e-81 270.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY69736.1 - 3.7e-07 30.2 0.0 5.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 KEY69737.1 - 2.6e-08 33.2 0.1 4.4e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69737.1 - 2.6e-05 24.3 10.5 4.3e-05 23.5 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fcf1 PF04900.12 KEY69738.1 - 5.8e-35 119.7 0.1 1.5e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KEY69738.1 - 5.8e-12 45.9 0.1 1.6e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 PIN like domain AAA_18 PF13238.6 KEY69738.1 - 0.046 14.3 0.2 0.12 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain GCV_T PF01571.21 KEY69738.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Rep_fac_C PF08542.11 KEY69739.1 - 2.8e-22 78.9 0.0 7.5e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KEY69739.1 - 2.7e-12 46.8 0.0 1e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KEY69739.1 - 1.9e-11 44.5 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEY69739.1 - 7e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY69739.1 - 3e-06 27.7 0.1 0.00016 22.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEY69739.1 - 2.8e-05 23.9 0.0 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEY69739.1 - 3.5e-05 24.1 0.1 0.12 12.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KEY69739.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KEY69739.1 - 0.00024 21.0 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEY69739.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KEY69739.1 - 0.0023 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MeaB PF03308.16 KEY69739.1 - 0.003 16.6 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KEY69739.1 - 0.003 17.0 0.0 0.028 13.8 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KEY69739.1 - 0.0071 16.7 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KEY69739.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY69739.1 - 0.0095 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DEAD PF00270.29 KEY69739.1 - 0.011 15.6 0.1 0.43 10.3 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KEY69739.1 - 0.011 16.0 0.1 0.03 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KEY69739.1 - 0.012 15.1 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KEY69739.1 - 0.012 15.4 0.0 0.075 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEY69739.1 - 0.016 15.2 0.0 0.061 13.3 0.0 2.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KEY69739.1 - 0.017 15.1 0.2 0.056 13.4 0.1 1.9 1 1 0 2 2 2 0 NTPase DNA_pol3_gamma3 PF12169.8 KEY69739.1 - 0.019 14.9 0.1 0.52 10.2 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_30 PF13604.6 KEY69739.1 - 0.049 13.4 0.1 0.16 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 KEY69739.1 - 0.099 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_25 PF13481.6 KEY69739.1 - 0.1 12.2 0.1 0.58 9.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain DER1 PF04511.15 KEY69741.1 - 3.2e-25 89.2 4.9 3.7e-25 89.0 4.9 1.0 1 0 0 1 1 1 1 Der1-like family LapA_dom PF06305.11 KEY69742.1 - 0.077 12.8 0.3 0.077 12.8 0.3 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 KEY69742.1 - 0.081 12.3 0.4 0.19 11.2 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CN_hydrolase PF00795.22 KEY69743.1 - 5.3e-14 52.2 0.0 8.5e-13 48.2 0.0 2.3 3 0 0 3 3 3 1 Carbon-nitrogen hydrolase DKCLD PF08068.12 KEY69745.1 - 4.2e-34 116.4 0.3 1.9e-32 111.1 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KEY69745.1 - 1.9e-22 79.1 1.7 3.7e-22 78.2 1.7 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KEY69745.1 - 5.3e-22 78.8 4.5 2.7e-16 60.3 0.1 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KEY69745.1 - 4.1e-21 74.7 0.5 9.2e-21 73.6 0.5 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KEY69745.1 - 0.00033 20.8 0.0 0.00083 19.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 KEY69745.1 - 0.91 9.4 8.6 1.9 8.4 8.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Glyco_hydro_43 PF04616.14 KEY69746.1 - 3.1e-26 92.3 0.0 4.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LapA_dom PF06305.11 KEY69747.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 KEY69747.1 - 0.16 12.9 0.0 0.39 11.6 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KEY69747.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family SAC3_GANP PF03399.16 KEY69748.1 - 1.1e-92 310.6 0.1 1.8e-92 309.8 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP family LTV PF04180.14 KEY69749.1 - 5.8e-131 437.8 15.1 6.6e-131 437.6 15.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 KEY69750.1 - 1.4e-16 60.6 0.3 3.5e-15 56.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY69750.1 - 1.1e-08 34.7 0.2 5.6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEY69750.1 - 1.4e-05 25.1 0.1 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KEY69750.1 - 0.0027 17.8 1.1 0.12 12.4 0.4 2.6 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 KEY69750.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Glyco_trans_2_3 PF13632.6 KEY69751.1 - 4.7e-50 170.3 4.9 4.7e-50 170.3 4.9 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEY69751.1 - 0.0073 16.1 0.0 0.092 12.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 KEY69752.1 - 7.6e-19 67.9 0.1 1.5e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GAS2 PF02187.17 KEY69753.1 - 2.7e-07 30.6 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HTH_50 PF18024.1 KEY69753.1 - 0.11 12.1 0.3 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Fungal_trans PF04082.18 KEY69754.1 - 6.1e-31 107.4 1.4 9.8e-31 106.8 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69754.1 - 4.8e-08 33.0 9.6 9.7e-08 32.0 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OMP_b-brl PF13505.6 KEY69754.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Malic_M PF03949.15 KEY69755.1 - 5.5e-93 311.0 0.0 8e-93 310.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEY69755.1 - 1.2e-71 240.2 0.0 2.1e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain POT1 PF02765.17 KEY69757.1 - 2.2e-11 43.7 0.0 4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 KEY69758.1 - 2.8e-35 121.7 0.0 2.3e-16 59.3 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY69758.1 - 1.8e-15 57.0 0.0 6.1e-12 45.4 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY69758.1 - 4.9e-12 45.7 0.0 3.2e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY69758.1 - 1.1e-11 44.4 0.1 7.7e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY69758.1 - 2.4e-08 34.1 0.4 2.4e-07 30.9 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEY69758.1 - 7.5e-08 32.3 0.0 0.0011 18.6 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEY69758.1 - 1.2e-07 31.3 0.0 2.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KEY69758.1 - 3e-07 30.6 0.0 1.1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEY69758.1 - 0.00046 19.0 0.2 0.086 11.5 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KEY69758.1 - 0.0014 18.0 0.0 0.042 13.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEY69758.1 - 0.0034 17.9 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY69758.1 - 0.0077 15.5 0.0 0.089 12.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Glu_dehyd_C PF16912.5 KEY69758.1 - 0.011 15.2 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KEY69758.1 - 0.017 15.2 0.0 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KEY69758.1 - 0.029 13.4 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Semialdhyde_dh PF01118.24 KEY69758.1 - 0.056 13.9 0.0 7.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MAF_flag10 PF01973.18 KEY69758.1 - 0.077 12.7 0.1 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF115 FAD_binding_2 PF00890.24 KEY69758.1 - 0.093 11.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KEY69758.1 - 0.15 12.4 0.1 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Aminotran_1_2 PF00155.21 KEY69759.1 - 2.8e-09 36.6 0.0 5.5e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Tannase PF07519.11 KEY69759.1 - 0.22 10.4 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Ribosomal_L4 PF00573.22 KEY69760.1 - 1.3e-36 126.1 0.1 1.8e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KEY69760.1 - 1.2e-25 89.3 1.8 1.2e-25 89.3 1.8 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PGA2 PF07543.12 KEY69762.1 - 3.2e-38 130.8 2.8 4.3e-38 130.4 2.8 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF2621 PF11084.8 KEY69762.1 - 0.092 12.7 0.1 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) GTP_EFTU PF00009.27 KEY69763.1 - 5.1e-57 192.6 0.1 6.8e-57 192.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEY69763.1 - 9.8e-25 87.0 0.0 1.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEY69763.1 - 2e-16 60.1 2.4 2e-16 60.1 2.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY69763.1 - 1.3e-05 25.3 0.1 2.5e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY69763.1 - 0.00076 19.4 0.1 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KEY69763.1 - 0.034 13.7 0.2 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEY69763.1 - 0.085 12.6 0.3 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.21 KEY69764.1 - 2.2e-14 52.9 2.1 2.5e-14 52.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KEY69764.1 - 0.07 13.1 0.6 0.078 12.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Thioredoxin PF00085.20 KEY69765.1 - 6.1e-59 196.4 0.0 2.9e-28 97.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KEY69765.1 - 1.2e-23 83.9 0.1 3.9e-23 82.2 0.0 2.0 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KEY69765.1 - 2.9e-18 66.3 0.1 9.9e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEY69765.1 - 1.7e-16 60.4 0.0 2.2e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KEY69765.1 - 9.4e-10 38.7 0.0 0.0024 18.2 0.0 3.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KEY69765.1 - 2.4e-09 37.2 0.0 0.00022 21.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KEY69765.1 - 2.4e-08 33.9 0.3 0.0092 15.9 0.0 3.1 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KEY69765.1 - 1.1e-05 25.2 0.4 0.1 12.3 0.1 2.4 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 KEY69765.1 - 2.8e-05 24.3 0.1 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain TraF PF13728.6 KEY69765.1 - 3.1e-05 23.9 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 KEY69765.1 - 0.00016 21.6 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 KEY69765.1 - 0.00036 20.5 0.1 0.79 9.6 0.0 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KEY69765.1 - 0.0004 20.4 0.0 0.64 10.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 KEY69765.1 - 0.00046 20.3 0.4 0.64 10.3 0.1 3.1 2 2 0 2 2 2 2 Glutaredoxin Thioredoxin_4 PF13462.6 KEY69765.1 - 0.001 19.3 0.4 0.94 9.6 0.0 3.0 2 2 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.6 KEY69765.1 - 0.0014 18.4 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin HSBP1 PF06825.12 KEY69766.1 - 1.6e-16 59.9 0.1 1.9e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 KEY69766.1 - 0.0067 16.5 0.1 0.0072 16.4 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 KEY69766.1 - 0.027 14.3 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 KEY69766.1 - 0.034 14.5 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CheX PF13690.6 KEY69766.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.3 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX zf-rbx1 PF12678.7 KEY69767.1 - 3.8e-10 39.9 1.9 7.2e-10 39.0 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEY69767.1 - 2.3e-07 31.1 9.0 1.2e-06 28.7 9.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEY69767.1 - 2.6e-07 30.4 2.1 4.3e-07 29.7 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY69767.1 - 4.6e-07 29.7 1.5 9.4e-07 28.7 1.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEY69767.1 - 9.2e-07 28.6 5.9 4.6e-06 26.4 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY69767.1 - 3.6e-06 26.9 2.1 1.3e-05 25.1 0.3 2.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KEY69767.1 - 0.00011 21.9 1.9 0.00023 21.0 1.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEY69767.1 - 0.00024 20.9 3.9 0.00036 20.3 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KEY69767.1 - 0.0017 17.9 1.0 0.0044 16.6 1.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KEY69767.1 - 0.0029 17.3 0.5 0.0029 17.3 0.5 3.4 4 0 0 4 4 4 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KEY69767.1 - 0.0036 17.3 0.6 0.011 15.8 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KEY69767.1 - 1.1 9.5 4.7 3.3 7.9 4.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_clus PF00172.18 KEY69768.1 - 1.4e-08 34.7 8.7 2.3e-08 34.0 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2719 PF10891.8 KEY69768.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) NECFESHC PF16621.5 KEY69770.1 - 0.13 12.2 1.1 3.7 7.6 0.1 2.8 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Rhomboid PF01694.22 KEY69771.1 - 1.8e-32 112.4 8.4 1.8e-32 112.4 8.4 1.6 2 0 0 2 2 2 1 Rhomboid family DNA_pol_B PF00136.21 KEY69772.1 - 9.1e-144 479.6 2.5 1.3e-143 479.1 2.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEY69772.1 - 2e-77 260.6 0.0 3.8e-77 259.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEY69772.1 - 5e-18 65.3 5.7 1.2e-17 64.1 5.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KEY69772.1 - 0.0034 16.3 0.2 0.021 13.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KEY69772.1 - 0.0051 16.8 0.1 0.045 13.7 0.1 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KEY69772.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-ACC PF17848.1 KEY69772.1 - 8 6.6 9.3 20 5.3 0.6 3.0 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain ELFV_dehydrog PF00208.21 KEY69773.1 - 9.6e-85 284.2 3.9 1.2e-84 283.9 3.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KEY69773.1 - 8.6e-52 174.4 0.0 1.8e-51 173.4 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KEY69773.1 - 0.018 15.5 0.2 0.041 14.3 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_transf_3 PF02515.17 KEY69774.1 - 5.1e-60 203.5 0.0 1.3e-59 202.2 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.20 KEY69775.1 - 1.4e-101 339.5 0.0 2.9e-101 338.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KEY69775.1 - 5.5e-57 192.5 0.0 1.1e-56 191.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KEY69775.1 - 7.8e-30 102.9 6.3 7.8e-30 102.9 6.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEY69775.1 - 5.9e-06 26.4 0.2 0.00018 21.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KEY69775.1 - 0.18 11.5 3.0 2.4 7.8 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain RTA1 PF04479.13 KEY69776.1 - 6.4e-66 221.9 1.8 6.4e-66 221.9 1.8 1.7 1 1 1 2 2 2 1 RTA1 like protein Trp_oprn_chp PF09534.10 KEY69776.1 - 0.033 14.0 0.1 0.29 10.9 0.0 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Exotox-A_bind PF09101.10 KEY69777.1 - 0.077 12.3 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding DUF3043 PF11241.8 KEY69777.1 - 1.2 9.1 2.6 1.1 9.2 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Peroxidase_2 PF01328.17 KEY69778.1 - 4.4e-47 161.0 0.1 5.1e-47 160.8 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.8 KEY69779.1 - 3.2e-09 36.1 0.7 4.3e-09 35.7 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 KEY69780.1 - 1e-20 73.7 17.0 4.3e-05 24.2 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69780.1 - 4e-12 46.3 0.9 0.00017 21.9 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KEY69780.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40_like PF17005.5 KEY69780.1 - 0.21 10.9 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain LPD25 PF18840.1 KEY69781.1 - 0.14 12.7 0.1 0.24 12.0 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 CAS_CSE1 PF03378.15 KEY69782.1 - 3.3e-159 530.1 0.0 1.3e-158 528.2 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KEY69782.1 - 6.7e-148 492.4 8.3 9e-148 492.0 8.3 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KEY69782.1 - 8.3e-13 48.1 0.3 3.4e-12 46.1 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KEY69782.1 - 0.0064 16.6 1.2 1.1 9.3 0.0 4.1 3 2 0 3 3 3 1 Exportin 1-like protein DUF3384 PF11864.8 KEY69783.1 - 1.2e-144 482.8 0.1 2.9e-144 481.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KEY69783.1 - 3e-51 173.6 0.0 1.8e-50 171.1 0.0 2.2 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 KEY69783.1 - 2.3e-31 109.2 7.1 2.4e-28 99.3 0.1 3.6 4 0 0 4 4 4 2 Tuberin DUF3361 PF11841.8 KEY69783.1 - 0.013 15.5 0.0 3.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DUF5576 PF17739.1 KEY69783.1 - 0.06 13.5 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5576) Acetyltransf_1 PF00583.25 KEY69785.1 - 8.4e-05 22.8 0.0 0.00027 21.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY69785.1 - 0.001 19.0 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY69785.1 - 0.0075 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY69785.1 - 0.0097 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY69785.1 - 0.092 12.7 0.5 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein CENP-I PF07778.11 KEY69786.1 - 1.3e-32 113.2 0.3 5.6e-31 107.8 0.3 2.1 1 1 0 1 1 1 1 Mis6 FANCF PF11107.8 KEY69786.1 - 0.16 11.2 4.7 0.15 11.2 1.0 2.4 2 1 0 2 2 2 0 Fanconi anemia group F protein (FANCF) ABC_tran PF00005.27 KEY69787.1 - 2.8e-15 57.0 0.0 1.4e-14 54.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEY69787.1 - 7.8e-11 42.3 0.1 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KEY69787.1 - 0.00065 17.4 0.1 0.00088 16.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KEY69787.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KEY69787.1 - 0.0019 17.7 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY69787.1 - 0.0038 17.6 0.5 0.0086 16.5 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KEY69787.1 - 0.0059 17.1 0.0 0.0084 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KEY69787.1 - 0.0064 16.2 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KEY69787.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KEY69787.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KEY69787.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEY69787.1 - 0.031 14.5 0.2 0.088 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEY69787.1 - 0.042 14.3 0.1 0.23 11.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEY69787.1 - 0.042 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEY69787.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KEY69787.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KEY69787.1 - 0.088 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEY69787.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY69787.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KEY69787.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 KEY69787.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DNA_pol_E_B PF04042.16 KEY69788.1 - 3.1e-48 163.9 0.0 4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KEY69788.1 - 1.3e-39 135.3 0.0 2.1e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain IMUP PF15761.5 KEY69789.1 - 0.34 11.6 4.6 0.55 10.9 2.1 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein PRIMA1 PF16101.5 KEY69789.1 - 1 9.4 9.5 2.2 8.3 9.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KEY69789.1 - 2.9 7.3 7.6 5.1 6.5 7.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PALP PF00291.25 KEY69790.1 - 3.6e-56 190.7 2.3 4.6e-56 190.4 2.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1181 PF06680.11 KEY69790.1 - 0.096 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Mito_morph_reg PF14972.6 KEY69790.1 - 0.23 11.1 1.2 0.59 9.7 0.1 2.0 2 1 0 2 2 2 0 Mitochondrial morphogenesis regulator DUF1610 PF07754.11 KEY69790.1 - 0.27 11.2 1.4 4.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CENP-S PF15630.6 KEY69791.1 - 7.3e-35 119.2 0.1 1.1e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KEY69791.1 - 2.7e-07 30.7 0.1 3.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KEY69791.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 KEY69791.1 - 0.015 15.3 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit WSC PF01822.19 KEY69792.1 - 6.6e-45 151.2 38.6 3.6e-17 62.3 10.4 3.6 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.23 KEY69792.1 - 1.8e-19 70.4 0.0 3.6e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Peroxidase MARVEL PF01284.23 KEY69793.1 - 1.4e-06 28.4 12.1 2.2e-06 27.8 12.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3402 PF11882.8 KEY69794.1 - 1.5e-210 700.2 0.0 1.9e-210 699.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KEY69794.1 - 1.7e-92 309.7 0.0 2.5e-92 309.1 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein NOA36 PF06524.12 KEY69794.1 - 7.2 5.8 6.0 13 5.0 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2011 PF09428.10 KEY69795.1 - 1.9e-20 72.9 0.5 9.9e-20 70.6 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.12 KEY69796.1 - 1.6e-32 113.3 0.0 2.9e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 KEY69797.1 - 3.6e-20 71.9 31.9 2.3e-14 53.3 0.9 4.1 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KEY69797.1 - 7e-16 58.5 0.0 1.4e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KEY69797.1 - 0.00031 20.7 5.3 0.00031 20.7 5.3 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 KEY69797.1 - 0.0016 18.7 34.2 0.0021 18.3 7.8 3.5 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 KEY69797.1 - 0.012 15.5 7.1 0.012 15.5 7.1 3.9 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_11 PF17123.5 KEY69797.1 - 0.016 15.0 6.7 0.016 15.0 6.7 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KEY69797.1 - 0.019 15.1 1.5 0.019 15.1 1.5 4.2 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KEY69797.1 - 3.7 7.5 35.4 0.038 13.8 8.1 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.21 KEY69798.1 - 1.9e-12 47.1 12.7 3.3e-12 46.3 9.2 2.4 2 1 0 2 2 2 1 PAP2 superfamily UbiA PF01040.18 KEY69798.1 - 0.0002 20.7 6.3 0.0002 20.7 6.3 1.9 2 0 0 2 2 2 1 UbiA prenyltransferase family BPD_transp_2 PF02653.16 KEY69798.1 - 0.0005 19.3 1.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF212 PF02681.14 KEY69798.1 - 0.0075 16.4 0.0 0.17 12.0 0.0 2.4 2 0 0 2 2 2 1 Divergent PAP2 family PAP2_3 PF14378.6 KEY69798.1 - 0.22 11.2 13.5 0.57 9.9 11.3 2.8 1 1 0 1 1 1 0 PAP2 superfamily DUF2070 PF09843.9 KEY69799.1 - 7.6 4.7 15.2 12 4.0 15.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Grg1 PF11034.8 KEY69800.1 - 4.5e-30 103.7 13.4 5e-30 103.5 13.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 EBP PF05241.12 KEY69801.1 - 4.6e-69 231.4 4.0 5.3e-69 231.2 4.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_kinase PF01513.21 KEY69802.1 - 9.7e-72 241.6 0.0 1.5e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KEY69802.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Egh16-like PF11327.8 KEY69806.1 - 0.12 12.7 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Egh16-like virulence factor IDO PF01231.18 KEY69806.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Epimerase PF01370.21 KEY69807.1 - 9.8e-07 28.5 0.0 2.5e-06 27.2 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY69807.1 - 1.8e-05 24.7 0.0 4.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Glyco_transf_4 PF13439.6 KEY69807.1 - 0.098 12.7 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_hydro_6 PF01341.17 KEY69808.1 - 4.6e-94 315.6 0.0 6e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Sugar_tr PF00083.24 KEY69809.1 - 3.7e-71 240.3 22.0 4.3e-71 240.1 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY69809.1 - 1.4e-18 67.0 25.4 1.4e-18 67.0 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KEY69809.1 - 0.21 11.4 1.9 0.58 9.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like OppC_N PF12911.7 KEY69809.1 - 1.3 9.1 5.7 0.3 11.1 0.6 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Amidoligase_2 PF12224.8 KEY69811.1 - 9.1e-10 38.6 0.0 6.2e-07 29.3 0.0 2.6 2 1 0 2 2 2 2 Putative amidoligase enzyme p450 PF00067.22 KEY69812.1 - 6.4e-39 134.0 0.0 9.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEY69813.1 - 1.2e-06 28.6 10.8 2.4e-06 27.6 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Siva PF05458.12 KEY69813.1 - 0.13 11.9 5.2 0.21 11.3 5.2 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CLN3 PF02487.17 KEY69814.1 - 3.3e-42 145.0 2.4 4.5e-42 144.5 2.4 1.1 1 0 0 1 1 1 1 CLN3 protein WD40 PF00400.32 KEY69817.1 - 3e-11 43.7 4.1 0.00026 21.7 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69817.1 - 0.0014 18.8 0.0 0.86 9.9 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KEY69817.1 - 0.21 12.1 1.0 3.1 8.4 0.0 3.2 3 2 1 4 4 4 0 PQQ-like domain Complex1_LYR PF05347.15 KEY69818.1 - 1.2e-20 73.3 4.8 1.6e-20 72.9 4.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY69818.1 - 7.8e-07 29.8 1.1 8.4e-07 29.6 1.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEY69818.1 - 0.00086 19.9 0.5 0.001 19.6 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KEY69818.1 - 0.22 11.5 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Fasciclin PF02469.22 KEY69821.1 - 9e-45 152.0 0.4 1.1e-24 87.1 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain FLgD_tudor PF13861.6 KEY69821.1 - 0.042 14.1 2.4 0.5 10.6 0.1 3.0 2 1 0 2 2 2 0 FlgD Tudor-like domain DNA_pol_A_exo1 PF01612.20 KEY69822.1 - 0.03 14.0 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease RNase_T PF00929.24 KEY69822.1 - 0.045 14.3 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 Exonuclease Methyltransf_23 PF13489.6 KEY69823.1 - 1.1e-24 87.2 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69823.1 - 8.9e-12 45.6 0.0 1.9e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY69823.1 - 5.2e-11 42.6 0.0 3.9e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY69823.1 - 2.9e-09 37.5 0.0 6.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY69823.1 - 5.4e-08 33.5 0.0 2.8e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY69823.1 - 0.00014 21.5 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEY69823.1 - 0.00066 19.2 0.0 0.0037 16.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KEY69823.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KEY69823.1 - 0.0055 16.8 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KEY69823.1 - 0.02 14.2 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEY69823.1 - 0.023 14.0 0.0 0.074 12.3 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KEY69823.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.22 KEY69824.1 - 1.7e-51 175.5 0.0 2.7e-51 174.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEY69827.1 - 8.1e-27 94.1 68.4 1.2e-24 86.9 48.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cloacin PF03515.14 KEY69828.1 - 0.069 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain S-methyl_trans PF02574.16 KEY69831.1 - 2.1e-49 168.7 0.0 4.5e-49 167.7 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase adh_short PF00106.25 KEY69831.1 - 6.7e-40 136.6 0.3 1.1e-39 135.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69831.1 - 8.5e-31 107.3 0.1 1.5e-30 106.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69831.1 - 1.2e-11 44.8 0.3 2.1e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY69831.1 - 0.11 12.0 0.2 0.21 11.0 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KEY69831.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Metaviral_G PF09595.10 KEY69831.1 - 0.22 11.6 5.2 0.54 10.3 5.2 1.6 1 0 0 1 1 1 0 Metaviral_G glycoprotein DAO PF01266.24 KEY69832.1 - 1.5e-46 159.6 4.3 1.8e-46 159.4 4.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY69832.1 - 7.2e-06 25.3 0.7 1e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY69832.1 - 5.3e-05 23.4 0.1 0.00012 22.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY69832.1 - 0.00012 22.6 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY69832.1 - 0.00094 18.5 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY69832.1 - 0.027 13.7 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 KEY69832.1 - 0.14 11.0 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 KEY69832.1 - 0.15 11.1 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein CBFD_NFYB_HMF PF00808.23 KEY69833.1 - 4.3e-18 65.3 0.5 6.1e-18 64.9 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY69833.1 - 4.3e-06 27.1 0.0 5.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KEY69833.1 - 0.094 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEY69833.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HEAT_PBS PF03130.16 KEY69833.1 - 0.16 12.7 0.0 14 6.7 0.0 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Isochorismatase PF00857.20 KEY69834.1 - 2.2e-40 138.7 0.2 2.5e-40 138.5 0.2 1.0 1 0 0 1 1 1 1 Isochorismatase family AA_permease PF00324.21 KEY69835.1 - 4.2e-118 395.0 40.1 4.8e-118 394.8 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY69835.1 - 2.7e-27 95.7 46.3 3.6e-27 95.3 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2263 PF10021.9 KEY69836.1 - 1.9e-21 76.9 0.0 4.8e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) BCS1_N PF08740.11 KEY69837.1 - 2.3e-42 145.1 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KEY69837.1 - 4.1e-17 62.8 0.0 6.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEY69837.1 - 0.00057 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KEY69837.1 - 0.0021 18.1 0.0 0.0083 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEY69837.1 - 0.0033 17.0 0.0 0.052 13.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY69837.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY69837.1 - 0.0061 17.0 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KEY69837.1 - 0.0088 15.8 0.0 0.028 14.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KEY69837.1 - 0.0096 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 KEY69837.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KEY69837.1 - 0.014 15.9 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEY69837.1 - 0.025 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEY69837.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEY69837.1 - 0.038 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY69837.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 KEY69837.1 - 0.088 13.2 0.0 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain PPV_E1_C PF00519.17 KEY69837.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 KEY69837.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AFOR_C PF01314.18 KEY69837.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ATP_bind_1 PF03029.17 KEY69837.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 KEY69837.1 - 0.26 11.2 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain F_bP_aldolase PF01116.20 KEY69838.1 - 1.5e-91 306.8 0.0 1.7e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 KEY69839.1 - 1.4e-60 205.1 0.4 2.3e-58 197.8 0.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Cid2 PF09774.9 KEY69840.1 - 4.5e-53 179.9 0.1 5.3e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AIM5 PF17050.5 KEY69840.1 - 0.096 13.5 1.6 1.4 9.8 0.0 2.7 2 1 0 2 2 2 0 Altered inheritance of mitochondria 5 NARP1 PF12569.8 KEY69841.1 - 3.5e-189 630.0 23.9 6e-150 500.6 11.0 3.2 3 0 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KEY69841.1 - 2e-19 69.9 23.3 0.0014 19.1 0.1 7.4 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEY69841.1 - 1.1e-14 54.8 27.6 0.005 17.5 0.0 9.2 8 1 3 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEY69841.1 - 1.3e-13 50.5 19.8 0.0053 17.5 0.0 10.0 7 4 4 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY69841.1 - 5.6e-13 47.9 27.5 0.001 19.0 0.1 10.3 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEY69841.1 - 2.5e-10 40.3 6.6 0.0013 18.8 0.1 6.0 5 2 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY69841.1 - 5.3e-10 39.4 17.1 0.004 17.4 0.4 5.2 4 2 1 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KEY69841.1 - 1.6e-08 34.1 12.3 2.4e-05 23.9 0.0 6.5 7 0 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 KEY69841.1 - 6.9e-08 32.0 24.6 8.3e-05 22.2 0.1 8.8 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY69841.1 - 7e-08 32.1 16.0 0.0012 18.8 0.1 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEY69841.1 - 1.6e-07 31.2 8.9 0.019 15.3 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY69841.1 - 1.7e-06 28.2 23.4 0.024 14.9 0.4 7.6 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 KEY69841.1 - 5.1e-06 26.6 3.5 0.32 11.7 0.6 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY69841.1 - 0.0025 17.7 8.7 30 5.0 0.0 6.8 5 1 1 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 KEY69841.1 - 0.0043 17.5 0.4 0.0043 17.5 0.4 3.4 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 KEY69841.1 - 0.085 12.8 11.7 15 5.6 0.0 7.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY69841.1 - 0.86 10.4 15.1 14 6.5 0.1 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Coilin_N PF15862.5 KEY69841.1 - 1.4 8.7 6.1 3.1 7.6 6.1 1.6 1 0 0 1 1 1 0 Coilin N-terminus MIT PF04212.18 KEY69841.1 - 2.9 8.0 15.4 15 5.7 0.1 5.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DAGK_cat PF00781.24 KEY69842.1 - 7e-25 87.1 0.0 1.1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BTB PF00651.31 KEY69843.1 - 3.7e-08 33.6 0.1 7.4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain RecQ_Zn_bind PF16124.5 KEY69843.1 - 0.081 13.7 0.5 7.9 7.3 0.0 3.4 2 1 0 3 3 3 0 RecQ zinc-binding tRNA_lig_kinase PF08303.11 KEY69843.1 - 0.15 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 tRNA ligase kinase domain SecE PF00584.20 KEY69845.1 - 5e-16 58.4 0.0 5.9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pre-SET PF05033.16 KEY69846.1 - 1.3e-18 67.7 4.6 1.4e-18 67.5 2.2 2.0 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 KEY69846.1 - 6.9e-17 62.3 0.2 5.6e-16 59.4 0.0 2.5 2 2 0 2 2 2 1 SET domain UBD PF16455.5 KEY69847.1 - 4.9e-39 132.8 0.1 7e-39 132.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KEY69847.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KEY69847.1 - 0.00088 19.8 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KEY69847.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KEY69847.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Adaptin_N PF01602.20 KEY69848.1 - 6.3e-95 318.7 4.2 1.1e-94 318.0 4.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KEY69848.1 - 3.1e-60 202.1 0.5 6.5e-60 201.1 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KEY69848.1 - 7e-56 187.7 0.0 1.9e-55 186.3 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KEY69848.1 - 1.1e-14 54.8 2.7 7.9e-11 42.3 0.0 2.9 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY69848.1 - 5.1e-08 33.2 5.0 0.00035 20.9 0.0 5.1 2 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KEY69848.1 - 0.0028 17.8 0.2 11 6.6 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KEY69848.1 - 0.13 12.8 0.8 14 6.3 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat AP4E_app_platf PF14807.6 KEY69848.1 - 0.13 12.6 0.3 0.52 10.7 0.3 2.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Fibin PF15819.5 KEY69848.1 - 1.5 8.6 4.0 0.82 9.4 0.1 2.3 3 0 0 3 3 3 0 Fin bud initiation factor homologue Mago_nashi PF02792.14 KEY69849.1 - 1.1e-71 239.6 0.2 1.2e-71 239.4 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 KEY69850.1 - 1e-69 233.5 1.6 1.3e-69 233.1 1.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.18 KEY69851.1 - 8.9e-08 32.0 0.0 0.001 18.8 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 KEY69852.1 - 5.3e-42 144.0 0.0 3.5e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.6 KEY69853.1 - 3.1e-10 40.1 0.0 1.5e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY69853.1 - 1.1e-06 29.0 0.0 5.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY69853.1 - 8.8e-06 25.7 0.3 0.0002 21.6 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KEY69853.1 - 0.00021 21.8 0.1 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KEY69853.1 - 0.0026 18.1 0.2 0.0055 17.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Lipoprotein_18 PF06804.11 KEY69853.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein RNA_lig_T4_1 PF09511.10 KEY69854.1 - 5.6e-86 287.9 0.0 9.8e-86 287.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KEY69854.1 - 4.7e-81 272.0 0.0 6.6e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KEY69854.1 - 8.1e-55 185.5 0.1 1.6e-54 184.5 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KEY69854.1 - 0.12 12.9 0.2 0.53 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_L10 PF00466.20 KEY69856.1 - 0.0076 16.4 0.0 0.028 14.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L10 AAA PF00004.29 KEY69857.1 - 1.1e-39 135.9 0.0 2.3e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEY69857.1 - 1.5e-18 66.5 0.1 3.1e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEY69857.1 - 5.4e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEY69857.1 - 0.00017 22.0 1.9 0.02 15.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEY69857.1 - 0.00018 21.5 0.1 0.00082 19.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEY69857.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEY69857.1 - 0.0014 18.9 1.4 0.088 13.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KEY69857.1 - 0.0018 18.4 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KEY69857.1 - 0.0068 15.9 0.2 0.091 12.2 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KEY69857.1 - 0.011 15.2 0.0 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEY69857.1 - 0.017 15.3 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEY69857.1 - 0.021 14.0 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KEY69857.1 - 0.059 13.1 0.2 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEY69857.1 - 0.12 12.1 0.1 0.44 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEY69857.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KEY69857.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.6 2 1 0 3 3 3 0 AAA domain RPN2_C PF18004.1 KEY69857.1 - 0.99 9.3 4.5 2.1 8.3 4.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ish1 PF10281.9 KEY69858.1 - 1e-90 297.7 21.9 6.4e-15 55.2 0.1 8.3 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KEY69858.1 - 3e-11 42.8 0.0 0.22 11.3 0.0 7.1 7 0 0 7 7 7 2 SAP domain HeH PF12949.7 KEY69858.1 - 1.1e-06 28.2 0.0 5.9 6.7 0.0 5.8 6 0 0 6 6 6 2 HeH/LEM domain Slx4 PF09494.10 KEY69858.1 - 9.6e-06 25.5 1.2 8.6 6.4 0.1 5.7 6 0 0 6 6 6 1 Slx4 endonuclease Endonuc-dimeris PF09124.10 KEY69858.1 - 0.0023 18.0 0.0 8.6 6.6 0.0 3.6 4 0 0 4 4 4 2 T4 recombination endonuclease VII, dimerisation DUF3612 PF12268.8 KEY69858.1 - 0.0066 16.6 0.1 39 4.3 0.0 4.7 4 2 1 5 5 5 0 Protein of unknown function (DUF3612) Thymopoietin PF08198.11 KEY69858.1 - 0.02 14.5 0.0 5.2 6.8 0.0 4.2 4 0 0 4 4 4 0 Thymopoietin protein SAM_2 PF07647.17 KEY69858.1 - 0.051 13.7 0.2 2.6 8.2 0.0 3.4 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) BOP1NT PF08145.12 KEY69859.1 - 3.8e-104 348.2 1.7 5.8e-104 347.6 1.7 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KEY69859.1 - 1.4e-24 85.9 2.7 1e-10 42.0 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69859.1 - 3e-05 24.2 0.0 0.17 12.2 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY69859.1 - 0.0094 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KEY69859.1 - 0.23 9.7 0.0 0.37 9.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Lipase_GDSL_2 PF13472.6 KEY69860.1 - 4.4e-25 89.1 2.6 6.8e-25 88.5 2.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY69860.1 - 1.2e-08 35.2 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ATG11 PF10377.9 KEY69861.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 DUF5065 PF16723.5 KEY69861.1 - 0.054 13.6 0.2 0.093 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) RT_RNaseH_2 PF17919.1 KEY69862.1 - 8e-23 80.4 0.0 1.3e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KEY69862.1 - 8e-19 67.9 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KEY69862.1 - 2e-05 24.4 0.0 0.00076 19.3 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase-like DUF4336 PF14234.6 KEY69862.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) 6PF2K PF01591.18 KEY69864.1 - 1.3e-55 188.2 0.0 1.8e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEY69864.1 - 1.2e-21 77.3 0.1 5e-21 75.3 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Porin_3 PF01459.22 KEY69865.1 - 3.5e-83 279.2 0.1 4e-83 279.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.6 KEY69866.1 - 2e-36 126.2 0.0 3.1e-34 119.0 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KEY69866.1 - 1.6e-13 50.7 0.0 9e-13 48.3 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 KEY69867.1 - 8.1e-28 96.4 0.0 2.1e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEY69867.1 - 1.5e-07 31.7 0.2 3.9e-07 30.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Fes1 PF08609.10 KEY69868.1 - 8.2e-30 103.5 4.9 5.2e-29 101.0 1.6 2.8 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 KEY69868.1 - 2.9e-07 30.2 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KEY69868.1 - 5.7e-07 29.8 0.2 3.2e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 KEY69868.1 - 3.3e-06 27.0 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEY69868.1 - 0.00013 22.4 0.1 0.00074 20.0 0.0 2.3 2 1 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 KEY69868.1 - 0.0025 16.5 1.3 0.17 10.4 0.1 2.1 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KEY69868.1 - 0.0064 16.6 0.4 0.19 11.8 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 KEY69868.1 - 0.01 15.8 0.2 0.035 14.1 0.1 1.8 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Actin PF00022.19 KEY69869.1 - 1.6e-151 504.6 0.0 5.8e-151 502.7 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 KEY69870.1 - 2.6e-24 85.4 2.2 3.6e-24 84.9 2.2 1.1 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 KEY69871.1 - 9.3e-25 86.0 6.5 1.3e-24 85.6 6.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 KEY69872.1 - 8.1e-31 105.6 23.3 0.00011 23.0 0.0 11.5 12 0 0 12 12 12 8 WD domain, G-beta repeat PD40 PF07676.12 KEY69872.1 - 0.02 14.8 0.2 26 4.9 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 KEY69872.1 - 0.12 12.4 0.0 21 5.2 0.0 4.1 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Mub_B2 PF17966.1 KEY69872.1 - 0.14 12.8 2.5 0.51 11.1 0.8 2.9 2 1 0 2 2 2 0 Mub B2-like domain Urm1 PF09138.11 KEY69873.1 - 2.7e-31 107.8 0.0 3.5e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KEY69873.1 - 0.00024 21.7 0.0 0.00033 21.2 0.0 1.2 1 0 0 1 1 1 1 ThiS family NAD_synthase PF02540.17 KEY69873.1 - 0.15 11.1 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 NAD synthase zf-C2H2 PF00096.26 KEY69874.1 - 3.4e-17 61.8 28.5 2.4e-05 24.5 2.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY69874.1 - 6.8e-16 57.9 26.7 2e-07 31.1 2.3 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY69874.1 - 4.1e-08 33.4 24.4 0.023 15.5 0.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KEY69874.1 - 0.031 14.6 13.5 0.21 11.9 4.0 3.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KEY69874.1 - 0.091 13.4 8.9 8.1 7.2 0.2 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KEY69874.1 - 0.48 10.6 7.7 4.4 7.4 2.9 3.1 2 1 1 3 3 3 0 Aberrant zinc-finger C1_4 PF07975.12 KEY69874.1 - 3.4 8.0 6.9 0.44 10.8 0.6 2.5 2 1 0 3 3 3 0 TFIIH C1-like domain zf-DNA_Pol PF08996.10 KEY69874.1 - 3.9 7.2 10.1 1.7 8.3 2.5 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-LYAR PF08790.11 KEY69874.1 - 9.9 6.2 11.4 17 5.4 0.2 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Mito_carr PF00153.27 KEY69875.1 - 2.8e-59 197.0 2.3 2.9e-20 72.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KEY69876.1 - 2e-34 117.2 0.0 6.8e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY69876.1 - 0.0099 16.0 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KEY69876.1 - 0.029 14.1 1.1 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 KEY69876.1 - 0.038 13.6 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY69876.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Cohesin_load PF10345.9 KEY69877.1 - 3.5e-113 379.1 3.6 4.7e-113 378.7 3.6 1.1 1 0 0 1 1 1 1 Cohesin loading factor Transglut_core PF01841.19 KEY69878.1 - 2.3e-10 40.9 0.6 6.9e-10 39.4 0.6 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KEY69878.1 - 1.3e-07 31.1 0.2 3.1e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY69878.1 - 0.00034 20.1 0.1 0.00034 20.1 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SARAF PF06682.12 KEY69878.1 - 0.0082 15.8 7.1 0.021 14.5 7.1 1.8 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SH3_9 PF14604.6 KEY69878.1 - 0.019 14.8 0.2 0.047 13.6 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 KEY69879.1 - 1.5e-69 234.3 0.0 2.1e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69879.1 - 1.9e-49 168.3 0.0 2.9e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY69879.1 - 2e-06 27.3 0.0 5.5e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEY69879.1 - 3.1e-06 26.2 0.0 6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Golgin_A5 PF09787.9 KEY69880.1 - 0.93 8.9 26.4 0.009 15.5 12.5 2.7 3 0 0 3 3 3 0 Golgin subfamily A member 5 Spc42p PF11544.8 KEY69880.1 - 1.4 8.9 7.3 0.17 11.9 1.5 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF4201 PF13870.6 KEY69880.1 - 1.5 8.5 21.4 0.76 9.5 12.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Nup54 PF13874.6 KEY69880.1 - 2.2 8.4 18.3 0.3 11.2 0.7 2.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 zf_PR_Knuckle PF18445.1 KEY69880.1 - 3.4 7.6 6.0 0.3 10.9 0.5 2.1 2 0 0 2 2 2 0 PR zinc knuckle motif CENP-F_leu_zip PF10473.9 KEY69880.1 - 3.8 7.5 23.6 6.1 6.9 15.2 2.9 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RAI1 PF08652.11 KEY69881.1 - 1.9e-26 92.0 0.0 5.8e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease COX5A PF02284.16 KEY69882.1 - 1.8e-40 137.1 0.2 2.3e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 KEY69883.1 - 1.9e-62 211.1 21.0 2.3e-62 210.8 21.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.7 KEY69884.1 - 1.4e-06 28.1 0.5 3e-06 27.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY69884.1 - 0.0043 16.9 0.2 0.033 14.1 0.2 2.3 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KEY69884.1 - 0.11 13.0 0.1 62 4.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Glycogen_syn PF05693.13 KEY69887.1 - 0 1165.8 0.0 0 1165.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KEY69887.1 - 2.5e-06 27.6 0.2 5e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KEY69887.1 - 1.4e-05 24.9 0.1 3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KEY69887.1 - 3.8e-05 23.3 0.0 0.006 16.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY69887.1 - 0.00012 22.5 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEY69887.1 - 0.00012 22.5 0.1 0.00031 21.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain WD40 PF00400.32 KEY69888.1 - 3.9e-19 68.6 10.5 1.1e-06 29.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KEY69888.1 - 3.8e-15 56.2 0.2 6e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KEY69888.1 - 0.08 11.6 1.4 0.42 9.2 0.6 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.20 KEY69889.1 - 3.3e-13 49.7 0.0 5.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 KEY69890.1 - 3.4e-22 77.9 0.1 3.8e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEY69890.1 - 0.026 14.6 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_L_2 PF13656.6 KEY69891.1 - 8e-22 76.8 0.1 1e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEY69891.1 - 3.5e-07 29.6 0.0 7.3e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MTS PF05175.14 KEY69892.1 - 1.8e-05 24.4 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 KEY69892.1 - 0.0027 18.2 0.4 0.015 15.9 0.4 2.2 1 1 0 1 1 1 1 PrmC N-terminal domain N6_Mtase PF02384.16 KEY69892.1 - 0.0028 17.0 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 KEY69892.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY69892.1 - 0.015 16.0 0.0 0.034 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KEY69892.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M41 PF01434.18 KEY69893.1 - 6.4e-68 228.4 0.0 1.1e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEY69893.1 - 8.5e-42 142.7 0.0 5.6e-41 140.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY69893.1 - 4.2e-14 52.1 0.0 1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KEY69893.1 - 1.2e-07 32.1 0.9 2.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 KEY69893.1 - 0.002 18.1 0.0 0.008 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEY69893.1 - 0.0043 16.3 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KEY69893.1 - 0.0089 16.2 0.0 0.062 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KEY69893.1 - 0.012 15.8 0.0 0.57 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEY69893.1 - 0.013 15.8 0.4 1.4 9.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KEY69893.1 - 0.016 14.9 0.0 0.062 13.0 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY69893.1 - 0.019 15.3 0.4 0.59 10.5 0.1 2.8 2 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KEY69893.1 - 0.035 14.7 1.1 2.8 8.5 0.1 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KEY69893.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KEY69893.1 - 0.16 11.5 0.2 0.75 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 KEY69894.1 - 1.3e-83 281.6 12.7 1.9e-46 159.0 3.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family TIMELESS PF04821.14 KEY69895.1 - 2.3e-88 296.1 0.0 2.3e-88 296.1 0.0 2.8 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KEY69895.1 - 2.3e-29 103.0 1.8 2.3e-29 103.0 1.8 4.2 2 1 2 4 4 4 1 Timeless protein C terminal region DUF3827 PF12877.7 KEY69895.1 - 0.0024 16.4 4.8 0.0024 16.4 4.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) 3HCDH_N PF02737.18 KEY69896.1 - 4.3e-52 176.6 0.6 5.5e-52 176.3 0.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEY69896.1 - 5.5e-33 113.4 0.0 3e-32 111.1 0.0 2.1 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KEY69896.1 - 0.0001 22.6 0.1 0.00021 21.5 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KEY69896.1 - 0.0025 18.0 0.1 0.0059 16.8 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KEY69896.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEY69896.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KEY69896.1 - 0.038 13.6 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KEY69896.1 - 0.051 13.2 0.1 0.27 10.9 0.0 2.0 1 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KEY69896.1 - 0.064 13.5 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 KEY69896.1 - 0.087 13.4 0.1 0.25 11.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KEY69896.1 - 0.1 13.2 1.1 0.56 10.8 1.1 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEY69896.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Homeodomain PF00046.29 KEY69897.1 - 7.9e-18 64.1 3.0 1.5e-17 63.2 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEY69897.1 - 0.0048 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Fox-1_C PF12414.8 KEY69897.1 - 0.0076 16.6 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Calcitonin gene-related peptide regulator C terminal Rox3 PF08633.10 KEY69898.1 - 1e-69 235.0 0.5 1e-69 235.0 0.5 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.18 KEY69899.1 - 1.3e-24 86.7 0.0 4.1e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY69899.1 - 1.8e-09 37.5 12.5 3.2e-09 36.8 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 KEY69899.1 - 0.16 10.6 1.0 0.29 9.8 0.0 1.8 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor SPX PF03105.19 KEY69899.1 - 0.75 9.7 14.4 0.41 10.5 7.0 2.2 2 0 0 2 2 2 0 SPX domain ATP11 PF06644.11 KEY69899.1 - 5.1 6.8 8.6 5.5 6.7 1.0 2.4 2 0 0 2 2 2 0 ATP11 protein FAD_binding_3 PF01494.19 KEY69901.1 - 1.1e-16 61.1 0.1 3.5e-09 36.4 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY69901.1 - 5.2e-07 29.8 0.1 1.7e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY69901.1 - 3.2e-06 27.6 0.1 0.00052 20.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY69901.1 - 5.1e-06 26.3 0.1 4.7e-05 23.1 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY69901.1 - 1.8e-05 24.1 0.0 0.0035 16.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY69901.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KEY69901.1 - 0.0078 15.3 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KEY69901.1 - 0.014 14.1 0.0 0.03 13.0 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KEY69901.1 - 0.042 13.1 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEY69901.1 - 0.08 11.8 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KEY69901.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KEY69901.1 - 0.2 11.7 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TPP_enzyme_N PF02776.18 KEY69903.1 - 8.4e-55 185.0 0.0 1.5e-53 180.9 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEY69903.1 - 2e-49 167.3 0.3 7.8e-48 162.1 0.1 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY69903.1 - 8.5e-40 135.7 0.7 1.9e-39 134.5 0.7 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TFIIA PF03153.13 KEY69904.1 - 1.8e-05 24.9 19.7 2.7e-05 24.4 19.7 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 KEY69904.1 - 0.054 13.8 14.2 0.1 12.9 14.2 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.16 KEY69904.1 - 0.091 12.8 6.4 0.2 11.7 6.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 KEY69904.1 - 0.39 10.1 9.5 0.62 9.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAT1 PF09770.9 KEY69904.1 - 0.41 8.8 28.7 0.58 8.4 28.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 KEY69904.1 - 0.44 10.9 11.4 1.1 9.6 11.4 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like BORG_CEP PF14957.6 KEY69904.1 - 1.1 10.5 7.9 3.3 8.9 7.9 1.9 1 0 0 1 1 1 0 Cdc42 effector Exonuc_VII_L PF02601.15 KEY69904.1 - 1.2 8.6 12.6 2 7.9 12.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.14 KEY69904.1 - 2.3 6.4 14.4 3.2 5.9 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 KEY69904.1 - 2.4 8.8 20.0 7.6 7.2 20.0 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 KEY69904.1 - 3.4 6.5 16.1 5 6.0 16.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 KEY69904.1 - 3.4 7.1 19.3 6.6 6.2 19.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 KEY69904.1 - 5.9 6.6 18.1 10 5.8 18.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KEY69904.1 - 7.2 5.3 18.2 11 4.7 18.2 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KEY69904.1 - 9 5.0 15.3 15 4.2 15.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 KEY69904.1 - 9.6 5.1 11.4 17 4.3 11.4 1.3 1 0 0 1 1 1 0 Tumour-associated protein zf-C2H2 PF00096.26 KEY69906.1 - 3 8.5 13.2 0.47 11.0 1.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type GalKase_gal_bdg PF10509.9 KEY69907.1 - 5.7e-21 73.8 0.1 1.1e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KEY69907.1 - 8.9e-15 54.7 2.6 3.2e-14 52.9 2.6 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEY69907.1 - 2.8e-12 46.8 0.9 5.5e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.12 KEY69907.1 - 0.011 15.4 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Zn_clus PF00172.18 KEY69908.1 - 7.5e-07 29.2 18.5 1.3e-06 28.5 18.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF739 PF05339.11 KEY69909.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF739) RINGv PF12906.7 KEY69911.1 - 0.00066 19.7 9.1 0.0011 19.1 9.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KEY69911.1 - 0.011 16.0 11.4 0.017 15.4 11.4 1.3 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KEY69911.1 - 0.23 11.7 7.5 0.44 10.8 7.5 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain CCDC53 PF10152.9 KEY69911.1 - 0.44 11.0 1.7 0.72 10.3 1.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex zf-C3HC4 PF00097.25 KEY69911.1 - 2.4 8.1 9.3 3.6 7.5 9.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2076 PF09849.9 KEY69911.1 - 9.3 6.2 9.7 17 5.4 9.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SGTA_dimer PF16546.5 KEY69912.1 - 3.8e-27 93.9 1.0 6.8e-27 93.0 1.0 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KEY69912.1 - 6.2e-16 57.5 4.3 1.6e-07 30.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY69912.1 - 2.4e-15 55.3 5.0 5.7e-06 26.0 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY69912.1 - 1.1e-09 37.8 2.8 7.7e-05 22.3 0.4 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KEY69912.1 - 4.8e-09 35.7 3.9 0.1 12.8 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY69912.1 - 2.2e-07 31.4 9.5 0.0011 19.6 3.2 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY69912.1 - 3e-06 27.6 7.3 0.0049 17.6 0.3 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEY69912.1 - 4.9e-06 26.6 4.8 0.021 15.2 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY69912.1 - 1.5e-05 25.4 2.9 0.0012 19.3 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY69912.1 - 2.4e-05 24.0 0.2 0.043 13.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY69912.1 - 0.00015 22.0 6.4 0.00035 20.8 2.5 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KEY69912.1 - 0.00093 19.1 6.2 0.0048 16.8 2.8 2.5 2 0 0 2 2 2 1 STI1 domain Serglycin PF04360.12 KEY69912.1 - 0.0021 18.0 0.3 0.0056 16.6 0.3 1.7 1 0 0 1 1 1 1 Serglycin TPR_6 PF13174.6 KEY69912.1 - 0.0069 16.9 3.1 1.4 9.7 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY69912.1 - 0.011 15.9 1.3 0.054 13.7 0.5 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 KEY69912.1 - 0.036 14.5 2.7 1.4 9.3 0.4 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KEY69912.1 - 0.038 13.9 5.6 2.7 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 KEY69912.1 - 0.041 13.6 0.9 0.094 12.5 0.2 1.9 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.18 KEY69912.1 - 0.043 13.9 2.0 1.2 9.3 0.4 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.27 KEY69913.1 - 6.1e-33 114.2 0.0 1.2e-32 113.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEY69913.1 - 2.6e-12 47.0 7.6 5.9e-12 45.8 7.6 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KEY69913.1 - 0.00051 19.6 0.0 0.0051 16.3 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KEY69913.1 - 0.0047 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KEY69913.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KEY69913.1 - 0.0074 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PAM2 PF07145.15 KEY69913.1 - 0.013 15.2 0.2 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_21 PF13304.6 KEY69913.1 - 0.029 14.2 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KEY69913.1 - 0.029 14.0 0.1 0.087 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY69913.1 - 0.043 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEY69913.1 - 0.083 13.4 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEY69913.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zn_clus PF00172.18 KEY69914.1 - 2.7e-05 24.2 4.4 0.00047 20.2 0.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ScdA_N PF04405.14 KEY69914.1 - 0.069 12.8 0.4 0.16 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) bZIP_1 PF00170.21 KEY69915.1 - 2e-10 40.6 1.2 2e-10 40.6 1.2 3.4 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 KEY69915.1 - 0.0029 17.7 1.0 0.0029 17.7 1.0 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Macoilin PF09726.9 KEY69915.1 - 1.7 7.1 18.4 2.1 6.8 18.4 1.2 1 0 0 1 1 1 0 Macoilin family XRCC4 PF06632.12 KEY69915.1 - 9.8 4.9 20.1 21 3.8 20.1 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF5320 PF17253.2 KEY69916.1 - 0.23 12.5 10.7 0.43 11.7 10.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5320) adh_short PF00106.25 KEY69917.1 - 5e-25 88.1 0.3 6.4e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69917.1 - 4.3e-19 69.0 0.1 6.7e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69917.1 - 1.3e-09 38.2 0.1 1.9e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY69917.1 - 7.8e-05 22.9 0.1 0.00012 22.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KEY69917.1 - 9.8e-05 21.6 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KEY69917.1 - 0.0067 17.0 0.3 0.038 14.6 0.2 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 KEY69917.1 - 0.011 15.7 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KEY69917.1 - 0.02 14.8 0.2 0.038 13.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY69917.1 - 0.056 12.9 0.2 0.15 11.5 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TraK PF06586.11 KEY69917.1 - 0.096 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TraK protein ApbA PF02558.16 KEY69917.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HET PF06985.11 KEY69918.1 - 2.7e-18 66.7 0.0 6.8e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAN_4 PF14295.6 KEY69919.1 - 0.0037 17.1 0.4 0.0072 16.2 0.4 1.5 1 0 0 1 1 1 1 PAN domain adh_short PF00106.25 KEY69920.1 - 1.6e-10 40.8 0.0 2.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY69920.1 - 0.00023 20.8 0.0 0.16 11.5 0.0 2.8 1 1 2 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY69920.1 - 0.012 15.5 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 KEY69920.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY69920.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KEY69922.1 - 1.7e-05 24.6 0.1 4.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY69922.1 - 0.00046 20.0 0.2 0.0013 18.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KEY69925.1 - 8.2e-101 327.1 69.4 9e-10 39.0 0.0 13.7 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69925.1 - 4.6e-31 107.0 27.0 7.1e-07 29.4 0.0 9.9 1 1 8 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY69925.1 - 2.8e-23 82.7 0.0 5.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KEY69925.1 - 1.9e-12 46.6 33.4 0.04 12.6 0.1 10.2 2 2 10 12 12 12 6 Nucleoporin Nup120/160 HET PF06985.11 KEY69925.1 - 1.7e-10 41.5 4.6 6.2e-08 33.1 0.3 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nbas_N PF15492.6 KEY69925.1 - 3e-07 30.1 26.8 0.25 10.6 0.1 9.1 2 2 8 11 11 11 4 Neuroblastoma-amplified sequence, N terminal DUF5114 PF17141.4 KEY69925.1 - 0.0008 19.9 0.3 26 5.5 0.0 5.6 4 1 2 6 6 6 0 Domain of unknown function (DUF5114) Ge1_WD40 PF16529.5 KEY69925.1 - 0.0033 16.4 30.5 0.48 9.3 0.0 7.5 1 1 5 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_19 PF13245.6 KEY69925.1 - 0.044 14.1 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain PNP_phzG_C PF10590.9 KEY69925.1 - 0.13 12.4 1.0 2.3 8.4 0.0 2.7 1 1 1 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region AAA_11 PF13086.6 KEY69925.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4358 PF14270.6 KEY69925.1 - 0.2 11.9 0.1 0.47 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Peptidase_M14 PF00246.24 KEY69926.1 - 1.5e-70 238.3 0.0 2e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TRAM PF01938.20 KEY69926.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 TRAM domain CHAT PF12770.7 KEY69928.1 - 9.6e-09 35.1 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 CHAT domain AAA_22 PF13401.6 KEY69928.1 - 1.6e-05 25.2 0.0 5.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY69928.1 - 0.015 15.7 0.0 0.053 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KEY69928.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KEY69928.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KEY69928.1 - 0.068 12.3 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF2867 PF11066.8 KEY69930.1 - 4.8e-34 117.8 0.0 5.8e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) tRNA-synt_His PF13393.6 KEY69931.1 - 4.7e-41 141.1 0.0 5.9e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KEY69931.1 - 2.5e-09 37.1 0.0 5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 KEY69931.1 - 0.0016 17.6 0.0 0.018 14.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) RHD3 PF05879.12 KEY69931.1 - 0.055 11.6 0.0 0.078 11.1 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) PAD PF03068.15 KEY69932.1 - 1e-124 416.5 0.0 1.3e-124 416.2 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Flavi_M PF01004.19 KEY69934.1 - 9.4 6.1 7.5 3 7.7 0.2 2.8 2 1 1 3 3 3 0 Flavivirus envelope glycoprotein M Acyl-CoA_dh_1 PF00441.24 KEY69935.1 - 2.6e-23 82.9 0.5 4.9e-23 82.0 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEY69935.1 - 2.3e-08 34.1 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEY69935.1 - 9.9e-07 29.4 0.1 2.4e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEY69935.1 - 1.4e-05 25.4 3.8 1.4e-05 25.4 3.8 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain IDO PF01231.18 KEY69936.1 - 4.1e-06 25.8 2.4 0.00012 21.0 2.3 2.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_C12 PF01088.21 KEY69937.1 - 6.8e-58 195.9 0.0 8.1e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MAD PF05557.13 KEY69939.1 - 5.5e-68 229.9 55.8 7e-68 229.6 54.2 1.6 1 1 1 2 2 2 1 Mitotic checkpoint protein DUF2353 PF09789.9 KEY69939.1 - 0.00015 21.3 3.5 0.00015 21.3 3.5 4.6 3 2 2 5 5 5 2 Uncharacterized coiled-coil protein (DUF2353) RVT_1 PF00078.27 KEY69939.1 - 0.13 11.7 0.1 0.37 10.3 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2070 PF09843.9 KEY69939.1 - 1.2 7.3 8.0 0.024 12.9 0.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF4618 PF15397.6 KEY69939.1 - 2 7.8 60.2 1.2 8.5 0.7 5.9 3 3 2 6 6 6 0 Domain of unknown function (DUF4618) GAS PF13851.6 KEY69939.1 - 2 7.7 90.3 0.065 12.6 8.1 6.4 3 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 KEY69939.1 - 2 8.9 42.8 2.1 8.8 0.2 8.5 8 1 2 10 10 10 0 Flagella accessory protein C (FlaC) Endotoxin_N PF03945.14 KEY69939.1 - 7.7 6.2 8.2 0.66 9.6 0.1 3.1 3 1 0 4 4 4 0 delta endotoxin, N-terminal domain Tam41_Mmp37 PF09139.11 KEY69940.1 - 1.1e-126 422.7 0.0 1.3e-126 422.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial muHD PF10291.9 KEY69941.1 - 1.7e-63 214.6 0.0 5.6e-63 212.9 0.0 1.8 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KEY69941.1 - 5.2e-06 26.7 2.6 6.2e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 KEY69941.1 - 0.027 14.0 9.5 0.01 15.4 6.0 1.8 2 0 0 2 2 2 0 Vps5 C terminal like Exonuc_VII_L PF02601.15 KEY69941.1 - 0.22 11.0 6.1 0.27 10.7 5.1 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Muted PF14942.6 KEY69941.1 - 0.36 11.2 7.8 0.16 12.3 4.6 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein GAS PF13851.6 KEY69941.1 - 0.86 8.9 7.7 2 7.7 7.7 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ALMT PF11744.8 KEY69941.1 - 0.89 8.3 3.3 1.3 7.7 3.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF416 PF04222.12 KEY69941.1 - 1.2 8.6 6.1 0.27 10.6 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Pkinase PF00069.25 KEY69942.1 - 3.4e-38 131.5 0.0 4.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY69942.1 - 2.8e-18 66.2 0.0 3.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY69942.1 - 0.03 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEY69942.1 - 0.032 14.2 0.2 0.25 11.2 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KEY69942.1 - 0.14 11.6 0.0 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 KEY69942.1 - 0.16 11.2 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like zf-RING_2 PF13639.6 KEY69943.1 - 1.6e-08 34.8 8.7 2.9e-08 33.9 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KEY69943.1 - 4.8e-06 26.7 8.3 1.4e-05 25.2 8.3 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KEY69943.1 - 8.9e-05 22.7 7.2 0.00022 21.4 7.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEY69943.1 - 0.00032 20.7 2.6 0.00079 19.4 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KEY69943.1 - 0.0005 20.1 7.4 0.0011 19.0 7.4 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 KEY69943.1 - 0.0048 16.7 9.5 0.0092 15.8 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KEY69943.1 - 0.0059 16.5 2.3 0.0059 16.5 2.3 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KEY69943.1 - 0.0083 15.7 5.2 0.017 14.7 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KEY69943.1 - 0.027 14.8 7.9 0.05 13.9 7.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KEY69943.1 - 0.03 14.2 5.7 0.054 13.4 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY69943.1 - 0.069 13.0 7.9 0.13 12.1 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KEY69943.1 - 0.85 9.6 6.1 1.9 8.4 6.1 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KEY69943.1 - 1.3 9.2 3.3 4 7.6 3.3 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_4 PF14447.6 KEY69943.1 - 1.3 8.9 6.4 4.1 7.3 6.4 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KEY69943.1 - 2.7 7.9 6.7 5.2 7.0 6.7 1.5 1 0 0 1 1 1 0 PHD-finger Ribosomal_L1 PF00687.21 KEY69947.1 - 3.8e-67 226.0 1.4 7.3e-67 225.1 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 KEY69948.1 - 7.7e-76 255.1 0.0 9.1e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 KEY69948.1 - 0.0094 15.5 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.11 KEY69948.1 - 0.075 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.23 KEY69949.1 - 9.8e-09 35.0 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3515 PF12028.8 KEY69949.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) DUF3646 PF12362.8 KEY69950.1 - 1.6 9.1 3.4 2.8 8.3 1.8 2.1 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Pmp3 PF01679.17 KEY69951.1 - 5.7e-19 68.1 9.2 7.5e-19 67.7 9.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 KEY69952.1 - 1e-121 406.9 0.0 1.2e-121 406.7 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 KEY69953.1 - 1.1e-49 169.0 0.0 1.7e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 KEY69953.1 - 1.1e-35 123.2 0.0 2.1e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KEY69953.1 - 9.1e-27 93.1 0.0 1.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KEY69953.1 - 4.5e-16 59.3 0.0 1.2e-15 57.9 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 KEY69953.1 - 4.8e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KEY69953.1 - 0.0012 18.7 0.2 0.0033 17.3 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 KEY69953.1 - 0.0024 17.9 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KEY69953.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY69953.1 - 0.012 15.1 0.1 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 KEY69953.1 - 0.012 15.4 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KEY69953.1 - 0.021 15.2 1.0 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KEY69953.1 - 0.064 13.3 0.0 0.45 10.6 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KEY69953.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KEY69953.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KEY69953.1 - 0.17 12.5 0.9 0.43 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.20 KEY69954.1 - 7.7e-35 120.0 25.4 1.4e-31 109.5 0.7 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY69954.1 - 2.4e-28 99.1 4.7 2.4e-28 99.1 4.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY69954.1 - 8.7e-19 68.6 0.3 6.6e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY69954.1 - 1.6e-16 59.7 0.0 4.2e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEY69954.1 - 3.4e-15 55.9 0.0 1.2e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY69954.1 - 1e-06 28.7 0.8 3e-05 23.9 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KEY69954.1 - 0.00083 19.3 1.4 0.0023 17.8 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) PvlArgDC PF01862.16 KEY69954.1 - 0.067 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Borrelia_P13 PF05628.12 KEY69954.1 - 0.11 12.5 0.5 0.74 9.8 0.3 2.5 2 0 0 2 2 2 0 Borrelia membrane protein P13 p6 PF17548.2 KEY69954.1 - 0.13 12.2 0.4 0.38 10.7 0.4 1.7 1 0 0 1 1 1 0 Histone-like Protein p6 IncE PF17627.2 KEY69954.1 - 3.3 7.7 7.4 0.23 11.5 0.5 2.4 2 0 0 2 2 2 0 Inclusion membrane protein E HET PF06985.11 KEY69955.1 - 7.6e-25 88.0 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CRAL_TRIO PF00650.20 KEY69956.1 - 1.6e-26 92.9 0.0 2.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEY69956.1 - 6.5e-09 35.8 0.1 1.5e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Chlorophyllase2 PF12740.7 KEY69958.1 - 0.023 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KEY69958.1 - 0.028 13.4 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 KEY69958.1 - 0.048 13.5 0.1 0.069 13.0 0.1 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold VWA_2 PF13519.6 KEY69959.1 - 1.1e-16 61.4 0.6 2.4e-16 60.3 0.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEY69959.1 - 6.2e-15 55.9 0.1 9.5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain AdHead_fibreRBD PF16812.5 KEY69959.1 - 0.0036 17.2 1.7 0.033 14.0 0.2 2.3 2 0 0 2 2 2 1 C-terminal head domain of the fowl adenovirus type 1 long fibre VWA_3 PF13768.6 KEY69959.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Tyrosinase PF00264.20 KEY69959.1 - 0.095 13.0 0.6 0.15 12.3 0.6 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF3669 PF12417.8 KEY69960.1 - 2.3e-16 59.8 0.1 7e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Zinc finger protein Zn_clus PF00172.18 KEY69961.1 - 0.14 12.4 15.1 0.082 13.0 2.1 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP59_mtransfer PF11735.8 KEY69963.1 - 2.2e-64 217.5 0.0 2.8e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CDT1_C PF16679.5 KEY69967.1 - 7.2e-24 84.1 0.0 7.2e-24 84.1 0.0 3.0 4 1 0 4 4 4 1 DNA replication factor Cdt1 C-terminal domain DUF3405 PF11885.8 KEY69968.1 - 4.1e-204 679.0 0.6 1.5e-202 673.9 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Rho_N PF07498.12 KEY69969.1 - 0.0071 16.3 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain DUF3338 PF11819.8 KEY69969.1 - 0.051 13.6 0.9 6.9 6.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) T3SSipB PF16535.5 KEY69969.1 - 0.1 13.1 0.1 0.16 12.4 0.1 1.3 1 1 0 1 1 1 0 Type III cell invasion protein SipB p450 PF00067.22 KEY69970.1 - 1.1e-51 176.0 0.0 4.1e-51 174.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 HAD_2 PF13419.6 KEY69973.1 - 3e-06 27.4 0.0 5.3e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY69973.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 KEY69973.1 - 0.04 14.2 0.0 0.088 13.1 0.0 1.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L5e PF17144.4 KEY69974.1 - 5e-79 264.0 0.3 8.9e-79 263.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KEY69974.1 - 9.8e-35 119.4 11.3 9.8e-35 119.4 11.3 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KEY69974.1 - 0.06 13.7 0.1 0.06 13.7 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Transposase_28 PF04195.12 KEY69975.1 - 0.024 14.8 0.0 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative gypsy type transposon LRR_6 PF13516.6 KEY69975.1 - 0.69 10.1 11.4 8.9 6.7 0.0 6.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KEY69975.1 - 3.2 8.7 4.8 1.9e+02 3.2 0.1 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat DUF5134 PF17197.4 KEY69976.1 - 0.04 13.8 0.3 0.76 9.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) PS_Dcarbxylase PF02666.15 KEY69977.1 - 1.7e-55 187.7 0.0 3.6e-55 186.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KEY69977.1 - 1.5e-39 134.4 0.0 1e-18 67.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 KEY69977.1 - 0.021 15.3 0.7 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KEY69977.1 - 0.024 14.2 0.0 0.078 12.5 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KEY69977.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KEY69977.1 - 0.083 12.9 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Fungal_trans PF04082.18 KEY69978.1 - 1.7e-15 56.8 0.4 2.9e-15 56.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY69978.1 - 1.4e-06 28.4 12.6 0.0036 17.7 2.0 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY69978.1 - 0.0033 18.1 10.5 0.29 12.1 2.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger CTP_transf_like PF01467.26 KEY69979.1 - 1.2e-30 106.5 0.0 2.2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like RRM_1 PF00076.22 KEY69980.1 - 2.2e-34 117.1 0.2 7.8e-16 57.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY69980.1 - 1.3e-12 47.7 0.2 6.5e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KEY69980.1 - 0.00036 20.5 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEY69980.1 - 0.031 14.3 0.1 6.9 6.8 0.0 2.9 2 0 0 2 2 2 0 RNA binding motif DUF3772 PF12607.8 KEY69980.1 - 0.51 10.1 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) TFIIA PF03153.13 KEY69980.1 - 0.8 9.6 28.4 1.2 9.1 28.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANTH PF07651.16 KEY69980.1 - 1.4 7.8 5.4 2 7.4 5.4 1.2 1 0 0 1 1 1 0 ANTH domain RabGAP-TBC PF00566.18 KEY69982.1 - 1.2e-47 162.4 0.0 3.1e-47 161.0 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pex14_N PF04695.13 KEY69982.1 - 0.091 13.4 3.0 0.74 10.5 1.3 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ELMO_CED12 PF04727.13 KEY69982.1 - 0.091 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Glyco_transf_90 PF05686.12 KEY69983.1 - 7.1e-14 51.5 0.6 9e-11 41.3 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Oxidored_q6 PF01058.22 KEY69984.1 - 3.2e-22 78.8 0.0 4.4e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.25 KEY69985.1 - 5.1e-96 321.8 0.0 7e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KEY69985.1 - 1.5e-34 117.8 24.7 7e-13 48.4 6.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KEY69985.1 - 3.1e-20 72.4 0.0 8e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 KEY69986.1 - 1.9e-16 59.6 0.0 2.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY69986.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NPV_P10 PF05531.12 KEY69986.1 - 0.082 13.4 0.3 0.15 12.6 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GPS2_interact PF15784.5 KEY69986.1 - 0.087 13.3 4.3 0.14 12.6 4.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain V_ATPase_I PF01496.19 KEY69986.1 - 0.11 10.4 0.4 0.14 10.1 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_occluded PF16842.5 KEY69986.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif EMP24_GP25L PF01105.24 KEY69986.1 - 0.23 11.4 0.6 0.32 10.9 0.6 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 KEY69986.1 - 0.98 9.2 4.8 1.5 8.6 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator GRP PF07172.11 KEY69986.1 - 1.2 9.9 16.0 0.048 14.4 10.1 1.7 2 0 0 2 2 2 0 Glycine rich protein family Ion_trans PF00520.31 KEY69987.1 - 1.4e-08 34.3 3.3 1.8e-08 33.9 3.3 1.1 1 0 0 1 1 1 1 Ion transport protein Mto2_bdg PF12808.7 KEY69987.1 - 0.015 15.6 0.3 0.028 14.7 0.3 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.18 KEY69987.1 - 0.022 15.0 0.4 0.035 14.3 0.4 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KEY69987.1 - 0.033 14.3 0.2 0.052 13.7 0.2 1.2 1 0 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.11 KEY69987.1 - 0.064 13.1 1.6 0.12 12.3 1.6 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 KEY69987.1 - 1.1 9.4 5.4 0.2 11.7 2.0 1.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF4588 PF15251.6 KEY69988.1 - 2.4e-06 27.5 0.5 3.7e-06 26.9 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Cytochrom_B562 PF07361.11 KEY69988.1 - 0.072 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 MSA-2c PF12238.8 KEY69988.1 - 0.53 10.3 4.9 0.96 9.4 4.9 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c SNF2_N PF00176.23 KEY69989.1 - 1.7e-76 257.2 0.2 3.5e-76 256.2 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KEY69989.1 - 4e-42 142.8 2.2 1.4e-41 141.1 2.2 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KEY69989.1 - 1.5e-35 122.2 4.9 1.5e-35 122.2 4.9 4.3 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KEY69989.1 - 1.5e-18 67.2 0.1 7.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY69989.1 - 3.4e-10 40.2 0.0 2.1e-09 37.6 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KEY69989.1 - 2.6e-05 23.5 0.0 0.00022 20.5 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KEY69989.1 - 0.00026 20.7 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 KEY69989.1 - 0.00051 19.9 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1086 PF06461.11 KEY69989.1 - 0.0032 17.3 0.1 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.31 KEY69989.1 - 0.0074 16.5 0.4 4.2 7.6 0.1 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_14 PF13173.6 KEY69989.1 - 0.081 13.0 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 KEY69989.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 WD40 PF00400.32 KEY69990.1 - 2.3e-24 85.2 1.8 5.7e-08 33.3 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY69990.1 - 6.3e-14 52.0 0.0 0.0076 16.5 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEY69990.1 - 0.0038 16.6 0.0 0.11 11.7 0.0 2.7 1 1 2 3 3 3 1 WD40-like domain eIF2A PF08662.11 KEY69990.1 - 0.005 16.7 0.1 2.2 8.1 0.0 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEY69990.1 - 0.0091 14.7 0.1 0.022 13.4 0.0 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KEY69990.1 - 0.033 13.2 0.1 0.25 10.3 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region SdiA-regulated PF06977.11 KEY69990.1 - 0.051 12.8 0.0 5.8 6.1 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated PQQ_2 PF13360.6 KEY69990.1 - 0.06 12.9 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain zf-MIZ PF02891.20 KEY69991.1 - 1.7e-06 27.6 8.6 1.1e-05 25.1 8.6 2.2 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_9 PF14604.6 KEY69992.1 - 4.8e-13 48.7 0.0 9.6e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KEY69992.1 - 7.4e-13 48.4 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KEY69992.1 - 1.5e-11 43.7 0.0 3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KEY69992.1 - 2.7e-10 40.7 0.0 1.3e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 KEY69992.1 - 0.00027 20.5 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KEY69992.1 - 0.00076 19.9 0.2 0.0021 18.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KEY69992.1 - 0.0016 18.7 0.0 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.30 KEY69992.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Forkhead PF00250.18 KEY69993.1 - 5.8e-13 48.9 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KEY69993.1 - 6.8e-06 26.4 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEY69993.1 - 0.025 14.9 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Otopetrin PF03189.13 KEY69994.1 - 0.16 10.8 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 Otopetrin MFS_MOT1 PF16983.5 KEY69995.1 - 9.5e-60 199.9 29.0 3.7e-33 114.2 10.0 2.5 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily PGAP1 PF07819.13 KEY69997.1 - 7.9e-07 29.0 0.1 2.2e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KEY69997.1 - 1.2e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KEY69997.1 - 5.3e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KEY69997.1 - 0.00022 20.9 0.0 0.002 17.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KEY69997.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEY69997.1 - 0.002 18.8 2.0 0.002 18.8 2.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 KEY69997.1 - 0.0034 16.6 0.0 0.0049 16.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KEY69997.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KEY69997.1 - 0.035 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF915 PF06028.11 KEY69997.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RTA1 PF04479.13 KEY69998.1 - 2.9e-28 98.9 8.3 3.9e-28 98.5 8.3 1.2 1 0 0 1 1 1 1 RTA1 like protein NAD_binding_6 PF08030.12 KEY70000.1 - 5.1e-20 72.2 0.0 7.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KEY70000.1 - 3.2e-17 62.8 18.3 1.3e-16 60.8 9.1 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEY70000.1 - 6.1e-10 39.2 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain DPPIV_N PF00930.21 KEY70001.1 - 1.3e-110 369.5 0.3 1.7e-110 369.2 0.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KEY70001.1 - 7.7e-54 182.4 3.5 8.2e-54 182.3 1.9 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEY70001.1 - 0.00044 20.0 0.5 0.0017 18.1 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY70001.1 - 0.0012 19.5 7.7 0.014 16.0 2.3 3.1 3 1 1 4 4 4 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KEY70001.1 - 0.014 15.0 0.6 0.05 13.2 0.3 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 KEY70001.1 - 0.35 10.9 5.1 1.3 9.1 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Arrestin_N PF00339.29 KEY70002.1 - 3.7e-14 53.0 0.0 7.2e-09 35.8 0.0 3.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEY70002.1 - 0.037 14.5 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.12 KEY70002.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus Clathrin PF00637.20 KEY70003.1 - 5e-204 668.4 37.8 1.5e-33 115.7 1.1 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KEY70003.1 - 7.7e-33 111.2 1.0 2.4e-08 33.9 0.2 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KEY70003.1 - 9.6e-33 111.9 0.7 4.7e-32 109.7 0.7 2.4 1 0 0 1 1 1 1 Clathrin-H-link TPR_14 PF13428.6 KEY70003.1 - 2.2e-05 24.9 6.2 22 6.2 0.0 8.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70003.1 - 0.0021 18.0 9.3 2.8 8.2 0.2 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY70003.1 - 0.0029 18.1 3.6 14 6.3 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Rop PF01815.16 KEY70003.1 - 0.016 15.1 0.7 0.066 13.1 0.2 2.4 2 0 0 2 2 2 0 Rop protein 6PF2K PF01591.18 KEY70003.1 - 0.049 12.9 0.1 0.18 11.1 0.1 1.9 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Coatomer_WDAD PF04053.14 KEY70003.1 - 0.049 12.7 12.9 3 6.8 0.3 5.0 6 0 0 6 6 6 0 Coatomer WD associated region Clathrin-link PF09268.10 KEY70003.1 - 0.055 12.9 0.1 0.2 11.1 0.1 2.1 1 0 0 1 1 1 0 Clathrin, heavy-chain linker VapB_antitoxin PF09957.9 KEY70003.1 - 0.12 12.3 1.5 3 7.8 0.0 3.5 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB TPR_12 PF13424.6 KEY70003.1 - 0.33 11.3 5.7 67 3.9 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1400 PF07176.11 KEY70003.1 - 0.37 11.1 2.7 27 5.1 0.0 3.9 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_2 PF07719.17 KEY70003.1 - 2.6 8.4 12.6 30 5.1 0.2 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M43 PF05572.13 KEY70005.1 - 3.9e-18 65.8 0.0 5.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KEY70005.1 - 8.2e-05 22.8 0.2 0.00012 22.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KEY70005.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KEY70005.1 - 0.025 14.2 0.5 0.046 13.4 0.5 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KEY70005.1 - 0.085 12.7 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin DUF2196 PF09962.9 KEY70006.1 - 2e-23 82.2 4.0 3.1e-23 81.5 4.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 KEY70006.1 - 0.0045 17.2 0.3 0.0063 16.8 0.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn_clus PF00172.18 KEY70007.1 - 0.05 13.7 14.7 0.077 13.1 14.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1640 PF07798.11 KEY70008.1 - 5.1e-57 192.7 6.5 6e-57 192.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KEY70008.1 - 0.02 14.3 0.3 0.051 13.0 0.1 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase 2 cwf21 PF08312.12 KEY70008.1 - 0.43 10.8 5.7 0.33 11.1 3.0 2.1 2 1 0 2 2 2 0 cwf21 domain DUF1690 PF07956.11 KEY70008.1 - 3.8 7.9 10.3 2.5 8.5 2.9 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) 2-Hacid_dh_C PF02826.19 KEY70009.1 - 4.7e-56 189.0 0.0 6.6e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY70009.1 - 2.3e-20 72.6 0.0 2.8e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEY70009.1 - 2e-05 24.8 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KEY70009.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KEY70009.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 KEY70010.1 - 1.1e-128 428.5 0.0 1.2e-74 251.1 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KEY70010.1 - 6.8e-82 273.3 2.1 1.2e-81 272.5 2.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEY70010.1 - 2.6e-06 26.9 0.1 6e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KEY70010.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 KEY70010.1 - 0.019 14.5 0.5 0.036 13.6 0.5 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Urocanase PF01175.18 KEY70010.1 - 0.19 11.4 1.0 0.36 10.5 1.0 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF5039 PF16442.5 KEY70010.1 - 0.25 10.8 0.4 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) JAB PF01398.21 KEY70011.1 - 4.7e-07 29.8 1.3 1.3e-05 25.1 1.3 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease STN PF07660.14 KEY70011.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Mito_carr PF00153.27 KEY70013.1 - 1.8e-42 143.2 3.3 3.8e-19 68.4 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF5566 PF17721.1 KEY70013.1 - 0.03 14.6 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5566) DUF1761 PF08570.10 KEY70013.1 - 0.14 12.5 0.4 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) SpoIIE PF07228.12 KEY70014.1 - 2.9e-10 40.4 0.1 5.8e-10 39.4 0.2 1.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEY70014.1 - 5.9e-07 29.3 0.4 1.1e-06 28.5 0.4 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEY70014.1 - 0.00069 19.3 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Ntox34 PF15606.6 KEY70014.1 - 0.088 12.9 0.1 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial toxin 34 BRO1 PF03097.18 KEY70016.1 - 1.6e-08 33.8 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.15 KEY70017.1 - 5.6e-126 421.3 32.1 1.2e-79 268.6 13.0 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ribosomal_60s PF00428.19 KEY70019.1 - 2.4e-27 95.3 11.3 2.7e-27 95.2 11.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KEY70019.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain SPT2 PF08243.11 KEY70020.1 - 4.5e-11 43.3 24.7 1.6e-08 35.0 24.7 2.6 1 1 0 1 1 1 1 SPT2 chromatin protein NUFIP1 PF10453.9 KEY70021.1 - 0.00014 21.6 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KEY70021.1 - 0.031 14.3 6.7 0.062 13.4 6.7 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KEY70021.1 - 0.19 11.7 5.8 0.38 10.7 5.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MCM3AP_GANP PF16769.5 KEY70021.1 - 0.71 8.1 2.7 1 7.5 2.7 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP RNA_pol_Rbc25 PF08292.12 KEY70022.1 - 1.1e-31 109.7 1.6 1.7e-30 105.9 1.6 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KEY70022.1 - 3.8e-13 49.6 0.0 5.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 EMC3_TMCO1 PF01956.16 KEY70023.1 - 2.5e-54 183.6 1.1 2.5e-54 183.6 1.1 1.5 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like TPPK_C PF12555.8 KEY70023.1 - 0.57 10.3 2.5 0.47 10.5 0.8 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SPC25 PF06703.11 KEY70024.1 - 1.4e-54 184.3 0.1 1.6e-54 184.0 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.6 KEY70025.1 - 1.2e-53 182.4 0.1 3e-53 181.1 0.1 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KEY70025.1 - 1.1e-13 51.1 0.1 1.2e-12 47.7 0.0 2.6 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal TAN PF11640.8 KEY70025.1 - 0.0039 17.3 1.0 1.4 9.0 0.0 3.7 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair ATP11 PF06644.11 KEY70026.1 - 1.8e-93 313.3 0.0 2.2e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein AMP-binding PF00501.28 KEY70027.1 - 4.4e-99 331.9 0.0 5.4e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY70027.1 - 9.9e-14 52.1 0.2 2e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydro_lipase PF04083.16 KEY70028.1 - 1e-19 69.9 0.0 3.2e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KEY70028.1 - 0.00018 21.2 0.1 0.00092 18.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY70028.1 - 0.041 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3899 PF13038.6 KEY70028.1 - 0.14 12.6 1.6 0.3 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) AAA PF00004.29 KEY70029.1 - 4.7e-51 172.7 0.0 1.8e-43 148.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY70029.1 - 6.4e-05 22.7 6.3 0.021 14.6 0.4 2.9 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KEY70029.1 - 7.6e-05 23.2 0.4 0.019 15.4 0.0 3.4 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KEY70029.1 - 0.0002 21.2 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KEY70029.1 - 0.00071 18.7 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 KEY70029.1 - 0.0036 17.4 0.0 0.0087 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KEY70029.1 - 0.0051 16.4 0.1 0.032 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEY70029.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KEY70029.1 - 0.0074 16.6 0.0 0.037 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEY70029.1 - 0.011 16.1 0.0 0.039 14.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase TIP49 PF06068.13 KEY70029.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 KEY70029.1 - 0.022 14.8 0.1 0.13 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEY70029.1 - 0.025 14.0 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KEY70029.1 - 0.037 13.5 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KEY70029.1 - 0.044 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KEY70029.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KEY70029.1 - 0.066 13.2 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KEY70029.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY70029.1 - 0.089 13.3 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEY70029.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY70029.1 - 0.18 11.8 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 KEY70030.1 - 1.8e-06 28.2 27.6 3.1e-06 27.4 27.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SH3BGR PF04908.15 KEY70030.1 - 2.4e-05 24.4 0.5 0.00032 20.8 0.0 2.9 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein DNA_pol_phi PF04931.13 KEY70030.1 - 0.64 8.1 41.9 1.4 6.9 41.9 1.6 1 0 0 1 1 1 0 DNA polymerase phi Hamartin PF04388.12 KEY70030.1 - 1 7.9 15.9 1.4 7.5 15.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3275 PF11679.8 KEY70031.1 - 2.6 8.0 6.9 0.2 11.6 2.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) MaoC_dehydratas PF01575.19 KEY70032.1 - 1.8e-06 27.5 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Phosphodiest PF01663.22 KEY70033.1 - 1.1e-14 54.9 0.2 2.3e-14 53.7 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEY70033.1 - 8.3e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KEY70033.1 - 0.0033 16.8 0.2 0.0057 16.1 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Cytochrom_B561 PF03188.16 KEY70034.1 - 0.00017 21.7 8.6 0.0003 21.0 8.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KEY70034.1 - 0.066 13.0 3.3 0.13 12.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Zn_clus PF00172.18 KEY70035.1 - 3.3e-09 36.7 5.0 6.7e-09 35.7 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY70035.1 - 2.8e-08 33.1 0.2 6.7e-07 28.6 0.1 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain HeLo PF14479.6 KEY70036.1 - 1.9e-34 119.3 5.8 4.3e-34 118.1 5.8 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KEY70036.1 - 0.0003 20.3 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SKA2 PF16740.5 KEY70036.1 - 0.00057 19.6 3.8 0.0017 18.1 3.8 1.8 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Pkinase_Tyr PF07714.17 KEY70036.1 - 0.001 18.4 0.6 0.0047 16.3 0.6 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY70037.1 - 5.1e-41 140.8 0.0 7.3e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70037.1 - 2.7e-27 95.7 0.0 4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEY70037.1 - 0.0039 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY70037.1 - 0.0056 16.6 0.0 3.8 7.4 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY70037.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 KEY70038.1 - 6.6e-10 39.4 0.0 2 9.4 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat INSIG PF07281.12 KEY70039.1 - 5.8e-72 241.8 0.8 7.1e-72 241.5 0.8 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Zn_clus PF00172.18 KEY70040.1 - 7e-09 35.7 7.9 7e-09 35.7 7.9 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Closter_coat PF01785.17 KEY70042.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Closterovirus coat protein SpoOE-like PF09388.10 KEY70042.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein E1-E2_ATPase PF00122.20 KEY70044.1 - 2e-46 157.8 0.1 8.8e-46 155.7 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEY70044.1 - 2.4e-38 132.5 0.1 4.5e-38 131.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEY70044.1 - 1.1e-34 118.6 0.7 3.3e-11 43.5 0.2 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.7 KEY70044.1 - 0.00011 22.7 0.0 0.0003 21.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEY70044.1 - 0.0024 17.6 0.2 0.0075 16.0 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.14 KEY70044.1 - 0.0057 17.0 3.1 2.3 8.6 0.1 3.7 3 1 1 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Importin_rep_3 PF18806.1 KEY70044.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat POTRA_1 PF08478.10 KEY70044.1 - 0.12 12.6 0.0 36 4.7 0.0 3.4 3 0 0 3 3 3 0 POTRA domain, FtsQ-type Cu-oxidase_2 PF07731.14 KEY70045.1 - 4.1e-41 139.9 8.5 1.1e-33 115.9 3.6 4.4 3 1 1 4 4 4 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY70045.1 - 3e-26 91.8 0.1 3e-26 91.8 0.1 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY70045.1 - 4e-18 66.0 0.2 6.3e-13 49.1 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase DUF1908 PF08926.11 KEY70045.1 - 0.13 11.3 1.4 0.22 10.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) tRNA-synt_2 PF00152.20 KEY70046.1 - 9.4e-44 149.7 0.0 1.4e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEY70046.1 - 1.9e-06 27.7 0.0 4.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 KEY70046.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) HTH_40 PF14493.6 KEY70046.1 - 0.12 12.8 0.3 0.32 11.5 0.3 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Zip PF02535.22 KEY70047.1 - 8.7e-62 209.3 11.7 1e-61 209.1 11.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4416 PF14385.6 KEY70048.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Chromo PF00385.24 KEY70048.1 - 0.17 11.8 0.7 1.5 8.7 0.1 2.5 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2956 PF11169.8 KEY70048.1 - 1.3 9.2 6.2 0.56 10.4 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Pex14_N PF04695.13 KEY70048.1 - 7.6 7.2 7.8 1.3 9.6 3.6 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_2 PF12796.7 KEY70049.1 - 0.0042 17.7 0.0 0.29 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Sterol-sensing PF12349.8 KEY70049.1 - 0.055 13.3 0.7 0.89 9.4 0.2 2.4 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Glyco_hydro_18 PF00704.28 KEY70050.1 - 4.9e-23 82.3 0.7 1.2e-22 81.1 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KEY70050.1 - 3.4e-05 23.8 0.0 7.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 LysM domain Fringe PF02434.16 KEY70052.1 - 3.3e-06 26.7 0.1 3e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KEY70052.1 - 0.00031 20.6 0.1 0.00056 19.8 0.1 1.3 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 KEY70052.1 - 0.045 13.6 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Galactosyltransferase UCH PF00443.29 KEY70053.1 - 3.3e-38 131.7 0.0 8.5e-34 117.2 0.0 2.5 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY70053.1 - 2.7e-07 30.5 2.4 0.031 13.8 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase F-box-like PF12937.7 KEY70055.1 - 0.00066 19.5 0.4 0.00066 19.5 0.4 2.0 2 0 0 2 2 2 1 F-box-like ATG11 PF10377.9 KEY70056.1 - 6.8e-43 145.8 0.5 6.8e-43 145.8 0.5 4.7 6 0 0 6 6 6 1 Autophagy-related protein 11 APG17 PF04108.12 KEY70056.1 - 0.00089 18.5 7.9 0.00089 18.5 7.9 7.2 3 3 1 4 4 2 1 Autophagy protein Apg17 CENP-F_leu_zip PF10473.9 KEY70056.1 - 0.0028 17.7 23.6 0.0028 17.7 23.6 7.5 7 2 0 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 KEY70056.1 - 0.0035 16.7 15.7 0.0035 16.7 15.7 7.6 6 1 1 8 8 7 1 Tropomyosin FmiP_Thoc5 PF09766.9 KEY70056.1 - 0.0045 16.3 5.9 0.0045 16.3 5.9 5.6 4 2 2 6 6 6 1 Fms-interacting protein/Thoc5 ERM PF00769.19 KEY70056.1 - 0.0048 16.8 29.4 0.0048 16.8 29.4 6.8 4 1 1 7 7 7 1 Ezrin/radixin/moesin family FERM_f0 PF16511.5 KEY70056.1 - 0.0049 17.1 0.2 0.7 10.2 0.0 2.7 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Fez1 PF06818.15 KEY70056.1 - 0.34 11.3 82.6 0.1 13.0 23.8 6.1 2 1 3 5 5 5 0 Fez1 EzrA PF06160.12 KEY70056.1 - 1.8 6.6 66.7 0.01 14.0 27.1 5.7 3 2 1 5 5 5 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 KEY70056.1 - 6.2 6.1 69.5 0.092 12.1 9.3 5.5 2 1 4 6 6 6 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KEY70056.1 - 6.6 4.1 85.4 0.13 9.8 26.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) CENP-H PF05837.12 KEY70057.1 - 2.4e-34 118.1 4.1 1.2e-33 115.8 0.9 2.2 2 1 0 2 2 2 1 Centromere protein H (CENP-H) DUF733 PF05306.11 KEY70057.1 - 0.11 12.8 0.5 0.3 11.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Gon7 PF08738.10 KEY70057.1 - 0.18 11.9 2.0 0.42 10.7 0.4 2.3 2 1 0 2 2 2 0 Gon7 family ATG16 PF08614.11 KEY70057.1 - 1.4 9.1 12.6 0.92 9.7 7.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KEY70057.1 - 1.6 9.4 6.1 0.45 11.2 0.9 2.3 3 0 0 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KEY70057.1 - 2.1 8.6 8.3 0.43 10.8 3.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KEY70057.1 - 5.2 7.6 8.0 20 5.7 1.0 2.8 2 1 0 2 2 2 0 Cell division protein ZapB HMG_box PF00505.19 KEY70058.1 - 6.1e-25 87.4 0.7 1e-24 86.7 0.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEY70058.1 - 2.2e-17 63.4 1.5 2.2e-17 63.4 1.5 1.7 1 1 1 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 KEY70058.1 - 0.0018 18.8 0.0 0.0018 18.8 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KEY70058.1 - 0.022 14.7 0.6 0.044 13.7 0.6 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KEY70058.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Prp31_C PF09785.9 KEY70058.1 - 0.18 12.7 3.6 0.2 12.6 3.6 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain PGM_PMM_I PF02878.16 KEY70060.1 - 1.2e-32 112.5 0.0 1.9e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEY70060.1 - 1.2e-25 89.9 0.0 1.9e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEY70060.1 - 1.8e-16 60.6 0.0 3.8e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEY70060.1 - 5.6e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 KEY70061.1 - 1.8e-25 90.4 0.0 2e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.22 KEY70062.1 - 1.1e-11 45.5 0.0 2.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEY70062.1 - 1.7e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SKG6 PF08693.10 KEY70063.1 - 0.0053 16.1 3.5 0.01 15.3 3.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Protocadherin PF08374.11 KEY70063.1 - 0.051 13.5 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin PDGLE PF13190.6 KEY70063.1 - 0.056 13.3 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 PDGLE domain Gram_pos_anchor PF00746.21 KEY70063.1 - 1.7 8.6 4.5 4.6 7.3 4.5 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF5423 PF17461.2 KEY70063.1 - 5.5 5.7 6.2 0.65 8.8 2.2 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Ribosomal_S19 PF00203.21 KEY70066.1 - 4.6e-33 112.9 0.2 6.5e-33 112.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KEY70066.1 - 0.046 13.4 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase Rax2 PF12768.7 KEY70067.1 - 0.0071 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity MerR-DNA-bind PF09278.11 KEY70067.1 - 0.053 14.1 0.4 0.096 13.2 0.4 1.4 1 0 0 1 1 1 0 MerR, DNA binding Glyco_hydro_53 PF07745.13 KEY70068.1 - 7.2e-104 347.4 0.0 8.1e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Tubulin PF00091.25 KEY70069.1 - 6.3e-60 202.8 0.0 1.1e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEY70069.1 - 2.2e-44 150.7 0.0 3.6e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KEY70069.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KEY70070.1 - 1.2e-14 53.9 0.3 3.4e-09 36.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 KEY70071.1 - 3.3e-12 46.9 0.7 3.3e-12 46.9 0.7 2.1 2 1 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.9 KEY70072.1 - 3e-06 27.2 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KEY70073.1 - 1.1e-63 214.9 0.0 6.4e-63 212.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DEDD_Tnp_IS110 PF01548.17 KEY70074.1 - 0.0044 16.9 1.0 0.0044 16.9 1.0 2.4 2 1 0 2 2 2 1 Transposase NRN1 PF15056.6 KEY70074.1 - 0.045 13.8 0.6 0.19 11.8 0.2 2.2 1 1 1 2 2 2 0 Neuritin protein family DUF4372 PF14294.6 KEY70074.1 - 0.15 12.3 0.2 0.36 11.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) 3Beta_HSD PF01073.19 KEY70076.1 - 8.5e-28 97.1 0.0 5.9e-13 48.4 0.0 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY70076.1 - 6.7e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY70076.1 - 6.4e-09 35.3 0.0 4.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KEY70076.1 - 9.7e-06 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEY70076.1 - 0.0052 16.0 0.2 0.69 9.0 0.1 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEY70076.1 - 0.011 15.1 0.0 0.097 12.1 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KEY70076.1 - 0.017 15.0 0.1 0.11 12.4 0.1 2.1 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KEY70076.1 - 0.1 11.6 0.0 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.18 KEY70076.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 KEY70077.1 - 8.6e-10 38.1 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY70079.1 - 1.2e-29 103.4 29.5 1.2e-29 103.4 29.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70079.1 - 7.7e-06 25.0 16.8 7.7e-06 25.0 16.8 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter DUF4022 PF13214.6 KEY70079.1 - 2.5 8.5 15.4 1.4 9.3 0.3 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4022) adh_short_C2 PF13561.6 KEY70081.1 - 7.7e-39 133.6 1.1 9.8e-39 133.3 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY70081.1 - 5.2e-33 114.2 0.6 6.5e-33 113.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY70081.1 - 2.8e-12 46.9 0.1 3.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY70081.1 - 0.083 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY70081.1 - 0.087 12.3 0.2 0.87 9.0 0.2 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KEY70082.1 - 5.3e-69 232.5 0.0 1.1e-68 231.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70082.1 - 1.2e-38 132.9 0.0 1.9e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY70082.1 - 2.3e-05 23.8 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEY70082.1 - 0.0051 16.8 0.7 0.038 13.9 0.7 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY70082.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEY70082.1 - 0.038 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEY70082.1 - 0.054 12.5 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 dCMP_cyt_deam_1 PF00383.23 KEY70083.1 - 1.5e-14 53.6 0.4 2e-14 53.3 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KEY70083.1 - 4.9e-06 26.8 6.7 3.3e-05 24.1 2.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KEY70083.1 - 7e-05 22.5 3.0 0.12 12.0 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases GrpE PF01025.19 KEY70086.1 - 2.5e-49 167.1 3.6 3.3e-49 166.7 3.6 1.1 1 0 0 1 1 1 1 GrpE HIP1_clath_bdg PF16515.5 KEY70086.1 - 0.13 12.8 4.5 6.5 7.4 1.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RFC1 PF08519.12 KEY70087.1 - 1.4e-57 194.3 0.2 3.3e-57 193.0 0.1 1.8 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KEY70087.1 - 9.4e-15 54.8 0.0 2.5e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KEY70087.1 - 2.2e-09 37.8 0.2 1.3e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEY70087.1 - 5.3e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KEY70087.1 - 5.8e-05 23.4 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY70087.1 - 0.00015 21.5 0.1 0.00041 20.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KEY70087.1 - 0.00033 20.5 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KEY70087.1 - 0.0025 18.2 1.2 0.0068 16.8 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 KEY70087.1 - 0.0088 16.0 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KEY70087.1 - 0.016 15.8 3.5 0.026 15.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KEY70087.1 - 0.022 14.7 0.0 0.29 11.0 0.0 2.6 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 KEY70087.1 - 0.03 14.5 0.0 0.089 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 KEY70087.1 - 0.04 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain AAA_14 PF13173.6 KEY70087.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEY70087.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KEY70087.1 - 0.11 12.8 2.2 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L16 PF00252.18 KEY70088.1 - 1.9e-31 108.8 1.6 3.3e-31 108.0 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KEY70088.1 - 2.3e-09 37.2 0.1 4.9e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KEY70088.1 - 2.3e-06 27.9 0.0 2.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY70088.1 - 8.2e-06 26.3 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY70088.1 - 0.00069 20.0 0.2 0.0051 17.2 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KEY70088.1 - 0.0026 17.5 0.1 0.0061 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 KEY70088.1 - 0.016 15.6 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain Rad17 PF03215.15 KEY70088.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KEY70088.1 - 0.063 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KEY70088.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AMP-binding PF00501.28 KEY70089.1 - 5.8e-83 278.8 0.0 7.3e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY70089.1 - 1e-27 96.9 1.1 1.8e-26 92.9 0.6 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEY70089.1 - 1.6e-19 69.5 0.2 4.9e-19 68.0 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 KEY70090.1 - 6.2e-58 196.2 3.1 6.2e-58 196.2 3.1 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KEY70090.1 - 1e-44 152.8 1.9 2.5e-44 151.5 1.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KEY70090.1 - 1.7e-42 145.4 0.4 3.5e-42 144.3 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KEY70090.1 - 4.7e-16 59.3 33.6 4.7e-16 59.3 33.6 4.7 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KEY70090.1 - 3.7e-09 37.2 3.2 1.2e-08 35.5 0.2 2.9 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KEY70090.1 - 0.00035 21.0 9.9 0.00035 21.0 9.9 4.3 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KEY70090.1 - 0.0021 18.3 0.1 0.0046 17.2 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 KEY70090.1 - 0.078 11.9 0.6 0.13 11.2 0.6 1.2 1 0 0 1 1 1 0 Peptidase M66 ANAPC4_WD40 PF12894.7 KEY70092.1 - 3.4e-07 30.5 0.1 0.13 12.5 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KEY70092.1 - 4.8e-07 29.5 0.1 8.5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.32 KEY70092.1 - 2.4e-06 28.2 15.9 0.026 15.4 0.0 7.9 8 1 0 8 8 8 2 WD domain, G-beta repeat DUF1751 PF08551.10 KEY70093.1 - 1.2e-25 89.9 7.7 2.1e-25 89.1 7.7 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KEY70093.1 - 0.65 10.0 11.5 1.1 9.3 11.5 1.3 1 0 0 1 1 1 0 Rhomboid family TPR_1 PF00515.28 KEY70094.1 - 1.2e-48 161.0 34.9 5.7e-08 32.3 0.1 10.9 12 1 0 12 12 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70094.1 - 5.9e-43 141.5 24.5 1.2e-05 25.1 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KEY70094.1 - 1.7e-31 105.8 24.9 6.5e-05 22.8 0.0 10.9 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 KEY70094.1 - 1.1e-26 91.2 15.0 9.2e-05 23.0 0.0 9.2 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 KEY70094.1 - 7.4e-26 90.5 16.0 6.4e-07 29.9 0.2 6.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KEY70094.1 - 6.7e-25 85.6 15.4 0.0014 18.9 0.1 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KEY70094.1 - 2.3e-22 78.4 31.5 1.6e-06 27.7 0.3 9.7 6 3 3 9 9 9 7 TPR repeat TPR_19 PF14559.6 KEY70094.1 - 2.5e-22 79.1 22.4 2.1e-05 24.9 0.3 7.0 5 3 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEY70094.1 - 2.8e-20 72.4 24.2 2.2e-05 24.7 0.6 7.2 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 KEY70094.1 - 3.2e-19 68.2 18.0 0.014 15.9 0.7 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70094.1 - 5.9e-15 54.1 14.2 0.011 15.7 0.0 9.5 9 2 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEY70094.1 - 5.7e-14 52.0 17.1 0.00089 19.4 0.1 6.4 3 1 5 8 8 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY70094.1 - 2.3e-12 47.0 12.6 2.6e-08 34.0 2.9 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KEY70094.1 - 1.8e-10 40.5 11.2 0.0063 15.8 1.8 5.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 KEY70094.1 - 8e-08 32.2 8.5 0.00081 19.2 2.7 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KEY70094.1 - 0.0033 17.7 1.3 1 9.7 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEY70094.1 - 0.01 15.9 2.0 14 5.8 0.0 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 KEY70094.1 - 0.017 14.9 5.4 0.13 11.9 0.4 3.3 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 KEY70094.1 - 0.057 13.3 19.0 7.9 6.5 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.6 KEY70094.1 - 0.15 11.5 17.8 18 4.6 0.2 5.5 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 KEY70094.1 - 0.15 12.5 8.8 2.6 8.5 0.2 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.18 KEY70094.1 - 5.6 7.1 21.4 20 5.4 0.1 6.5 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.22 KEY70095.1 - 4.2e-180 598.6 11.6 4.7e-180 598.4 11.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 KEY70096.1 - 0.0038 17.6 0.0 0.37 11.2 0.0 2.2 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Chorismate_bind PF00425.18 KEY70097.1 - 6.4e-92 307.8 0.0 1.1e-90 303.7 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KEY70097.1 - 1.4e-26 93.4 0.1 5e-22 78.6 0.0 4.2 3 1 1 4 4 4 2 Anthranilate synthase component I, N terminal region IMS PF00817.20 KEY70099.1 - 2.1e-39 134.9 0.0 3.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEY70099.1 - 4.5e-12 46.7 0.0 1e-11 45.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4332 PF14229.6 KEY70099.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) IMS_HHH PF11798.8 KEY70099.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif DUF726 PF05277.12 KEY70100.1 - 5e-100 334.8 0.0 6.9e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DENN PF02141.21 KEY70101.1 - 1e-58 198.4 0.0 1.6e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KEY70101.1 - 1.8e-15 56.6 0.8 3.7e-15 55.6 0.8 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KEY70101.1 - 1.9e-14 54.1 0.0 4.6e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 KEY70101.1 - 0.012 15.9 7.4 0.024 14.9 7.4 1.4 1 0 0 1 1 1 0 C1 domain SPA PF08616.10 KEY70101.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 KEY70101.1 - 0.06 13.3 4.4 0.14 12.0 4.4 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KEY70101.1 - 0.18 11.7 8.2 0.43 10.5 8.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KEY70101.1 - 0.19 11.8 2.2 0.4 10.8 2.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HIT PF04438.16 KEY70101.1 - 2.1 8.3 3.5 3.7 7.5 3.5 1.3 1 0 0 1 1 1 0 HIT zinc finger HTH_Tnp_Tc5 PF03221.16 KEY70102.1 - 2.6e-05 24.1 0.8 9.1e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain NACHT PF05729.12 KEY70103.1 - 2.8e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KEY70103.1 - 5.3e-05 22.5 0.0 0.089 12.0 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 KEY70103.1 - 0.0033 17.0 0.0 0.0091 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Ses_B PF17046.5 KEY70103.1 - 0.0078 16.2 2.2 0.0092 15.9 0.9 1.8 2 0 0 2 2 2 1 SesB domain on fungal death-pathway protein AAA_16 PF13191.6 KEY70103.1 - 0.0097 16.3 0.1 0.35 11.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY70103.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3759 PF12585.8 KEY70106.1 - 6.1e-38 128.7 3.5 8.4e-38 128.3 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) UPF0270 PF06794.12 KEY70106.1 - 0.039 14.0 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) adh_short PF00106.25 KEY70107.1 - 2.1e-22 79.5 0.0 3.9e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70107.1 - 4.2e-17 62.5 0.2 5.2e-17 62.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY70107.1 - 5.9e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY70107.1 - 4.9e-06 26.2 0.0 8.2e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY70107.1 - 0.00071 19.5 0.1 0.0016 18.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEY70107.1 - 0.017 14.5 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Abhydrolase_3 PF07859.13 KEY70109.1 - 6.7e-38 130.7 0.0 8.3e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KEY70109.1 - 3.5e-05 23.5 0.0 0.00025 20.7 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEY70109.1 - 0.00018 21.1 0.0 0.0014 18.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEY70109.1 - 0.0011 18.6 0.3 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KEY70109.1 - 0.0014 18.4 0.0 0.0038 17.1 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KEY70109.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KEY70109.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 KEY70109.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KEY70109.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KEY70109.1 - 0.39 10.2 1.8 0.35 10.3 0.2 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase p450 PF00067.22 KEY70110.1 - 2.8e-70 237.4 0.0 1.2e-68 232.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KEY70110.1 - 4.7e-27 95.0 0.0 7.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEY70110.1 - 1.8e-26 93.1 0.0 3.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEY70110.1 - 2.2e-13 50.8 0.0 9.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KEY70110.1 - 0.022 15.0 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain SRP54 PF00448.22 KEY70111.1 - 2.1e-76 255.9 1.0 2.1e-76 255.9 1.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KEY70111.1 - 5e-31 107.3 4.8 5e-31 107.3 4.8 3.9 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KEY70111.1 - 2.5e-20 72.5 0.4 5.9e-20 71.3 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KEY70111.1 - 9.9e-07 28.5 1.2 4.9e-06 26.2 0.7 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEY70111.1 - 1.9e-06 28.1 0.2 8.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY70111.1 - 9.1e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KEY70111.1 - 3.8e-05 23.1 0.0 8.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KEY70111.1 - 0.00024 21.5 0.1 0.00024 21.5 0.1 2.5 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 KEY70111.1 - 0.00073 18.6 0.4 0.00073 18.6 0.4 2.7 2 1 0 2 2 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KEY70111.1 - 0.0015 18.3 0.1 0.0052 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KEY70111.1 - 0.0022 18.1 0.0 0.0078 16.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KEY70111.1 - 0.0032 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 KEY70111.1 - 0.0042 16.8 0.2 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase ATP_bind_1 PF03029.17 KEY70111.1 - 0.0043 16.9 0.3 0.039 13.7 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KEY70111.1 - 0.0048 17.4 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEY70111.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KEY70111.1 - 0.0093 15.4 0.8 2.8 7.4 0.1 3.2 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEY70111.1 - 0.01 15.9 0.2 0.17 12.0 0.1 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase ResIII PF04851.15 KEY70111.1 - 0.011 15.8 0.2 0.044 13.8 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEY70111.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEY70111.1 - 0.017 15.0 1.6 1.5 8.7 1.6 2.3 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.18 KEY70111.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 KEY70111.1 - 0.023 14.6 0.1 0.095 12.6 0.0 2.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KEY70111.1 - 0.028 14.7 0.1 0.07 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KEY70111.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Torsin SKA2 PF16740.5 KEY70111.1 - 0.64 9.8 5.3 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4149 PF13664.6 KEY70112.1 - 1.4e-19 70.2 2.8 2.4e-19 69.5 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) GAGA_bind PF06217.12 KEY70112.1 - 0.24 11.6 7.3 0.49 10.6 7.3 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 KEY70112.1 - 0.58 9.3 5.9 0.077 12.2 1.7 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter SAPS PF04499.15 KEY70112.1 - 0.86 8.3 3.4 1.2 7.9 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 KEY70112.1 - 5.2 6.4 9.4 8.3 5.8 9.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 KEY70112.1 - 5.7 5.6 11.3 8.2 5.1 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2151 PF10221.9 KEY70112.1 - 6.1 5.3 9.7 9.1 4.7 9.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RNA_pol_Rpc4 PF05132.14 KEY70112.1 - 9 6.7 14.1 28 5.1 14.1 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 Formyl_trans_N PF00551.19 KEY70113.1 - 1.5e-37 129.0 0.2 1.9e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KEY70113.1 - 1.7e-10 40.5 0.0 2e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KEY70113.1 - 8.9e-05 22.4 0.1 0.00056 19.8 0.0 2.3 2 0 0 2 2 2 1 ACT domain FtsK_alpha PF17854.1 KEY70113.1 - 0.13 12.4 0.2 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 FtsK alpha domain Thymidylate_kin PF02223.17 KEY70114.1 - 7.8e-42 143.0 0.0 8.9e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KEY70114.1 - 4.2e-07 30.4 0.0 6.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY70114.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.18 KEY70114.1 - 0.027 14.2 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 KEY70114.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GATase PF00117.28 KEY70116.1 - 6.8e-36 123.8 0.0 1.4e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KEY70116.1 - 2.5e-35 120.4 0.0 5.3e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KEY70116.1 - 2.1e-09 36.8 0.0 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KEY70116.1 - 2.5e-08 34.0 0.1 4.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KEY70116.1 - 0.0031 16.3 0.0 0.0064 15.3 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KEY70116.1 - 0.028 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 KEY70116.1 - 0.053 13.0 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 KEY70116.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Glyco_hydro_11 PF00457.17 KEY70117.1 - 4.3e-59 199.1 8.1 5.1e-59 198.9 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PLAC8 PF04749.17 KEY70118.1 - 5.1e-08 33.8 2.8 8.9e-08 33.0 2.8 1.3 1 0 0 1 1 1 1 PLAC8 family Phage_holin_2_4 PF16082.5 KEY70120.1 - 0.14 11.9 0.5 0.31 10.8 0.5 1.6 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ras PF00071.22 KEY70121.1 - 4.1e-31 107.8 0.1 5.2e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY70121.1 - 1e-23 83.8 0.1 1.8e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY70121.1 - 3.5e-06 26.6 0.1 4.8e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEY70121.1 - 0.001 18.5 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KEY70121.1 - 0.013 14.4 0.0 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) GCV_H PF01597.19 KEY70122.1 - 1.1e-28 99.6 0.2 1.3e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Pollen_allerg_1 PF01357.21 KEY70122.1 - 0.18 11.9 0.0 1.6 8.8 0.0 2.1 1 1 0 2 2 2 0 Pollen allergen Porphobil_deam PF01379.20 KEY70123.1 - 3.5e-79 265.0 0.1 6.2e-79 264.2 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KEY70123.1 - 5.6e-17 61.9 0.0 1.1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PNTB PF02233.16 KEY70125.1 - 3.5e-172 573.5 25.3 3.5e-172 573.5 25.3 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KEY70125.1 - 4.6e-76 254.9 0.1 1.7e-75 253.0 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KEY70125.1 - 3.9e-49 166.5 0.2 1.5e-48 164.6 0.0 2.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KEY70125.1 - 1.2e-29 102.6 4.1 1.2e-29 102.6 4.1 5.5 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KEY70125.1 - 0.00053 19.4 0.1 0.44 9.9 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KEY70125.1 - 0.018 14.3 0.1 0.039 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KEY70125.1 - 0.055 13.5 0.2 0.24 11.4 0.2 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GIDA PF01134.22 KEY70125.1 - 0.088 11.9 0.8 0.15 11.1 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Cytochrom_B561 PF03188.16 KEY70125.1 - 0.12 12.5 5.5 0.032 14.4 1.3 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NAD_binding_8 PF13450.6 KEY70125.1 - 2.7 8.3 6.8 0.32 11.3 1.2 2.6 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NDUFA12 PF05071.16 KEY70126.1 - 2.3e-28 98.8 0.2 2.9e-28 98.6 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KEY70127.1 - 2.6e-14 53.2 0.0 4.6e-08 33.0 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEY70127.1 - 2.1e-07 30.8 1.0 0.004 17.3 0.2 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif DUF5349 PF17298.2 KEY70127.1 - 0.4 10.4 1.1 0.59 9.8 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Ribosomal_L4 PF00573.22 KEY70128.1 - 2.6e-48 164.3 0.0 3.7e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.20 KEY70129.1 - 7.8e-07 29.5 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cep57_CLD_2 PF14197.6 KEY70129.1 - 0.081 13.0 0.9 0.17 12.0 0.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 KEY70130.1 - 9.3e-13 48.1 2.9 9.3e-13 48.1 2.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY70130.1 - 1.5e-06 28.2 2.3 1.5e-06 28.2 2.3 2.4 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY70130.1 - 0.00021 21.7 1.6 0.00021 21.7 1.6 2.6 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF4407 PF14362.6 KEY70130.1 - 0.51 9.7 1.7 0.68 9.2 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_45 PF02015.16 KEY70131.1 - 3.8e-80 268.7 14.2 4.5e-80 268.5 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Peptidase_M20 PF01546.28 KEY70132.1 - 1.3e-33 116.5 0.1 1.8e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KEY70132.1 - 0.00076 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 KEY70132.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase dimerisation domain Ribosomal_S13_N PF08069.12 KEY70132.1 - 0.12 12.5 1.0 0.23 11.5 1.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain FMO-like PF00743.19 KEY70133.1 - 1.5e-61 208.4 0.0 2e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY70133.1 - 1.8e-15 57.0 0.0 2.8e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY70133.1 - 1.8e-12 47.1 0.0 1.2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY70133.1 - 1.2e-08 35.1 0.1 2.1e-06 27.8 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY70133.1 - 3.3e-08 33.6 0.0 7.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY70133.1 - 2e-05 24.4 0.1 0.021 14.4 0.1 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KEY70133.1 - 4.1e-05 22.9 0.7 0.00058 19.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KEY70133.1 - 5.2e-05 22.7 0.0 0.84 8.9 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEY70133.1 - 0.00023 21.7 0.1 0.12 13.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY70133.1 - 0.00041 19.7 0.2 0.001 18.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEY70133.1 - 0.00073 18.4 0.0 0.0027 16.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KEY70133.1 - 0.0017 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEY70133.1 - 0.0021 17.2 0.1 0.0034 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEY70133.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KEY70133.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 KEY70133.1 - 0.028 14.9 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Glu_dehyd_C PF16912.5 KEY70133.1 - 0.048 13.1 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KEY70133.1 - 0.082 13.3 0.0 1 9.8 0.0 2.4 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KEY70133.1 - 0.091 11.8 0.0 0.22 10.6 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Thermopsin PF05317.11 KEY70133.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Thermopsin Shikimate_DH PF01488.20 KEY70133.1 - 0.19 11.8 0.1 5.1 7.2 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEY70133.1 - 0.21 11.5 0.2 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cellulase PF00150.18 KEY70135.1 - 3.2e-20 72.7 3.3 4.4e-20 72.3 3.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEY70135.1 - 2.6e-09 36.6 0.0 2.8e-08 33.2 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KEY70135.1 - 0.00036 20.0 0.1 0.00094 18.6 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_61 PF03443.14 KEY70136.1 - 3.6e-55 187.1 0.0 4.9e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyoxalase PF00903.25 KEY70137.1 - 5.5e-05 23.4 0.2 7.6e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HET PF06985.11 KEY70138.1 - 1e-26 94.0 0.0 4.4e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.11 KEY70139.1 - 9.9e-05 22.5 8.7 0.00028 21.0 8.7 1.6 1 1 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 KEY70139.1 - 0.0065 16.5 2.4 0.015 15.3 2.4 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF347 PF03988.12 KEY70139.1 - 0.0097 16.1 0.3 0.02 15.1 0.3 1.5 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) DUF4448 PF14610.6 KEY70139.1 - 0.064 13.0 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 KEY70139.1 - 0.19 11.5 0.2 0.19 11.5 0.2 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Mucin PF01456.17 KEY70139.1 - 0.9 9.5 23.5 0.046 13.7 17.3 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein PBP PF01161.20 KEY70141.1 - 2.5e-09 37.5 0.2 3.5e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pheromone PF08015.11 KEY70141.1 - 0.022 15.8 0.0 0.059 14.4 0.0 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone ADH_zinc_N PF00107.26 KEY70142.1 - 6.6e-24 84.3 2.0 1.4e-23 83.3 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY70142.1 - 2.8e-16 60.8 0.2 6.3e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY70142.1 - 2.1e-14 53.3 0.1 6.8e-14 51.7 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.24 KEY70142.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CtnDOT_TraJ PF07863.11 KEY70142.1 - 0.12 13.1 2.9 1.4 9.6 0.1 3.3 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon 2-Hacid_dh_C PF02826.19 KEY70142.1 - 0.2 11.0 0.6 0.5 9.7 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KEY70143.1 - 2.7e-13 49.6 0.4 5e-13 48.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY70143.1 - 1e-07 32.0 7.5 0.0033 17.8 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY70143.1 - 7.4e-05 23.3 8.0 0.0077 17.0 3.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY70143.1 - 0.16 12.3 3.3 0.38 11.1 1.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY70143.1 - 0.69 10.4 2.5 2.1 8.8 1.4 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KEY70143.1 - 2.8 8.5 14.1 1.6 9.3 4.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Pribosyl_synth PF14572.6 KEY70144.1 - 1.1e-39 136.4 0.6 3.4e-35 121.7 0.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KEY70144.1 - 9.5e-31 106.1 0.0 1.8e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KEY70144.1 - 8.4e-14 51.4 0.3 1.5e-13 50.5 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEY70144.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase F-box-like PF12937.7 KEY70147.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like Peptidase_M14 PF00246.24 KEY70148.1 - 1e-81 275.0 0.0 1.3e-81 274.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KEY70148.1 - 5.9e-06 26.6 0.0 2.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Response_reg PF00072.24 KEY70150.1 - 2.2e-22 79.4 0.2 4e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KEY70150.1 - 3.1e-19 69.5 0.0 5.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEY70150.1 - 1.7e-06 27.9 2.4 1.1e-05 25.3 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KEY70150.1 - 1.4e-05 25.2 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KEY70150.1 - 0.00016 21.9 0.0 0.00082 19.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KEY70150.1 - 0.00018 21.4 0.0 0.00053 19.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 KEY70150.1 - 0.00081 19.7 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 KEY70150.1 - 0.0056 16.9 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KEY70150.1 - 0.016 15.2 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold Peptidase_S8 PF00082.22 KEY70151.1 - 4.8e-27 95.0 17.0 1.6e-26 93.3 17.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY70151.1 - 5.5e-11 43.0 0.5 1.3e-10 41.8 0.5 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 Chromo PF00385.24 KEY70152.1 - 4.3e-05 23.3 3.1 0.018 14.9 0.1 2.9 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Bradykinin PF06753.12 KEY70155.1 - 0.05 13.3 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 Bradykinin Glyco_hydro_18 PF00704.28 KEY70157.1 - 2e-20 73.8 0.3 4.3e-18 66.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CE2_N PF17996.1 KEY70159.1 - 1.3e-16 60.5 0.0 2.4e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 KEY70159.1 - 1.1e-14 55.3 0.1 1.6e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY70159.1 - 1.1e-06 28.7 0.1 2.2e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRTP PF01366.18 KEY70162.1 - 0.038 12.1 10.8 0.073 11.1 2.4 2.0 2 0 0 2 2 2 0 Herpesvirus processing and transport protein LprI PF07007.12 KEY70163.1 - 0.053 14.2 0.5 0.079 13.6 0.1 1.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI DASH_Duo1 PF08651.10 KEY70163.1 - 0.14 12.0 0.1 24 4.8 0.0 2.7 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF4482 PF14818.6 KEY70163.1 - 0.15 13.0 0.0 0.2 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DUF4287 PF14117.6 KEY70164.1 - 0.1 12.8 0.1 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Ank_2 PF12796.7 KEY70165.1 - 9.2e-20 71.0 2.0 2.2e-07 31.4 0.3 6.0 4 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY70165.1 - 1.6e-19 70.0 5.2 3.7e-07 30.6 0.1 6.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY70165.1 - 2.5e-13 48.9 6.7 0.00022 21.4 0.0 9.6 11 0 0 11 11 11 3 Ankyrin repeat Ank PF00023.30 KEY70165.1 - 4e-09 36.5 12.7 0.00042 20.6 0.1 7.4 8 1 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KEY70165.1 - 1.8e-07 31.3 7.1 0.00038 20.7 0.1 5.8 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY70166.1 - 3.1e-67 223.2 8.8 8.5e-10 39.1 1.2 10.1 7 3 2 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY70166.1 - 2.4e-57 190.6 21.0 4e-09 36.8 0.3 14.3 9 5 5 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY70166.1 - 1.7e-50 163.1 22.6 0.00019 21.6 0.1 19.5 20 1 0 20 20 20 11 Ankyrin repeat Ank PF00023.30 KEY70166.1 - 2e-47 157.6 38.3 0.00012 22.3 0.0 17.3 18 1 0 18 18 18 11 Ankyrin repeat Ank_5 PF13857.6 KEY70166.1 - 4.6e-42 141.5 35.4 1.9e-06 28.0 0.5 14.1 7 5 7 14 14 14 10 Ankyrin repeats (many copies) AAA_16 PF13191.6 KEY70166.1 - 0.0014 19.0 0.7 0.025 15.0 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY70166.1 - 0.044 14.1 0.1 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEY70166.1 - 0.091 11.9 0.0 0.24 10.5 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain DUF241 PF03087.14 KEY70167.1 - 0.35 10.7 0.2 0.5 10.2 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Glyco_hydro_61 PF03443.14 KEY70168.1 - 2.5e-59 200.7 0.0 3.1e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KEY70168.1 - 0.012 15.9 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Mpv17_PMP22 PF04117.12 KEY70170.1 - 3.3e-18 65.7 0.1 7.3e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KEY70170.1 - 0.095 13.0 4.1 0.1 12.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) Amidohydro_3 PF07969.11 KEY70171.1 - 1.9e-69 235.3 0.6 2.3e-69 235.1 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KEY70171.1 - 4.4e-11 42.7 0.0 4e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family APH PF01636.23 KEY70172.1 - 5.2e-11 42.9 0.0 1.7e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank PF00023.30 KEY70173.1 - 2.9e-06 27.5 1.3 0.0028 18.0 0.6 3.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KEY70173.1 - 5.3e-05 23.7 0.6 0.01 16.4 0.0 3.8 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY70173.1 - 0.00078 19.7 0.2 0.37 11.5 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KEY70173.1 - 0.0016 19.0 0.2 0.057 14.0 0.0 3.5 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY70173.1 - 0.0082 16.4 0.1 0.44 10.9 0.0 3.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Cu_amine_oxid PF01179.20 KEY70174.1 - 7.2e-126 420.4 7.4 9.5e-126 420.0 7.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KEY70174.1 - 1e-22 79.6 0.1 2.6e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KEY70174.1 - 3.6e-07 30.3 0.0 1.8e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Ank_2 PF12796.7 KEY70175.1 - 9.4e-16 58.2 0.1 2.2e-06 28.2 0.0 4.5 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY70175.1 - 8.9e-14 50.3 9.2 0.0035 17.7 0.4 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KEY70175.1 - 2.5e-12 47.0 2.5 0.0024 18.4 0.1 6.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY70175.1 - 7.6e-09 35.7 9.6 0.006 16.9 0.1 6.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY70175.1 - 9.7e-09 35.3 16.4 0.01 16.2 1.3 7.0 7 0 0 7 7 7 4 Ankyrin repeat Peptidase_S8 PF00082.22 KEY70176.1 - 3.6e-31 108.5 11.9 8.6e-31 107.3 11.9 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY70176.1 - 4.3e-07 30.5 0.0 1.7e-06 28.6 0.1 2.1 2 1 0 2 2 2 1 Peptidase inhibitor I9 CspB_prodomain PF18425.1 KEY70176.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Csp protease B prodomain Form_Nir_trans PF01226.17 KEY70177.1 - 1e-74 250.8 19.0 1.2e-74 250.6 19.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter STI1 PF17830.1 KEY70178.1 - 0.02 14.8 8.4 0.11 12.4 0.3 3.3 2 2 0 2 2 2 0 STI1 domain PPR_2 PF13041.6 KEY70178.1 - 0.12 12.6 0.6 0.26 11.5 0.6 1.7 1 0 0 1 1 1 0 PPR repeat family Relaxase PF03432.14 KEY70178.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain BRX_N PF13713.6 KEY70178.1 - 0.2 11.5 1.0 1.2 9.0 0.3 2.5 2 1 1 3 3 3 0 Transcription factor BRX N-terminal domain HET PF06985.11 KEY70179.1 - 1.9e-31 109.4 0.0 3.4e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Globin PF00042.22 KEY70179.1 - 5.4e-08 33.4 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KEY70179.1 - 7.1e-07 29.5 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEY70179.1 - 8.9e-06 26.3 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 KEY70179.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Protoglobin NAD_binding_6 PF08030.12 KEY70179.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 3 0 0 3 3 3 0 Ferric reductase NAD binding domain Piwi PF02171.17 KEY70180.1 - 5.9e-67 226.0 0.0 8.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEY70180.1 - 1.6e-17 64.4 0.1 5.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KEY70180.1 - 4.2e-14 52.0 0.3 1.4e-13 50.3 0.3 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KEY70180.1 - 9.9e-14 51.4 0.0 4.6e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KEY70180.1 - 4.1e-12 46.1 0.0 1.1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 PAZ domain Spc7 PF08317.11 KEY70181.1 - 9.9e-09 34.5 231.7 0.0049 15.8 22.4 10.0 1 1 8 9 9 9 6 Spc7 kinetochore protein HMMR_N PF15905.5 KEY70181.1 - 2.9e-05 23.7 209.7 0.0099 15.4 28.2 8.4 1 1 7 8 8 7 5 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 KEY70181.1 - 4.7e-05 23.0 185.6 0.061 12.8 17.4 8.5 1 1 8 9 9 9 6 Golgin subfamily A member 5 Atg14 PF10186.9 KEY70181.1 - 6.6e-05 22.1 26.3 6.6e-05 22.1 26.3 8.8 1 1 7 8 8 7 1 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 KEY70181.1 - 0.00023 21.1 9.2 0.00023 21.1 9.2 14.4 1 1 12 14 14 11 2 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KEY70181.1 - 0.00064 19.8 275.8 0.043 13.9 27.1 11.6 1 1 11 13 13 13 5 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KEY70181.1 - 0.0007 19.9 19.5 0.0007 19.9 19.5 8.9 1 1 8 9 9 9 2 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KEY70181.1 - 0.00072 19.0 26.7 0.00072 19.0 26.7 8.2 1 1 5 7 7 4 2 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 KEY70181.1 - 0.0024 17.3 11.0 0.0024 17.3 11.0 8.5 1 1 6 8 8 7 4 Tropomyosin Rab5-bind PF09311.11 KEY70181.1 - 0.0033 16.9 24.6 0.0033 16.9 24.6 7.7 1 1 5 7 7 7 4 Rabaptin-like protein ADIP PF11559.8 KEY70181.1 - 0.011 15.9 14.4 0.011 15.9 14.4 13.9 1 1 14 15 15 13 0 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KEY70181.1 - 0.037 14.3 0.5 0.037 14.3 0.5 9.7 11 1 0 11 11 8 0 Homeobox associated leucine zipper WEMBL PF05701.11 KEY70181.1 - 0.16 10.6 267.7 0.0062 15.3 15.1 8.5 1 1 6 7 7 6 0 Weak chloroplast movement under blue light Pox_A_type_inc PF04508.12 KEY70181.1 - 0.18 11.7 2.6 7.8 6.5 0.0 4.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Filament PF00038.21 KEY70181.1 - 0.7 9.4 188.7 0.36 10.3 7.0 8.6 1 1 5 7 7 7 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KEY70181.1 - 2 8.4 86.2 0.039 14.0 4.2 10.3 1 1 6 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus APH PF01636.23 KEY70182.1 - 5.9e-10 39.5 3.7 8e-10 39.0 3.7 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY70182.1 - 3e-05 23.7 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEY70182.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KEY70182.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Mannosyl_trans3 PF11051.8 KEY70183.1 - 0.00076 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative ABC_tran PF00005.27 KEY70184.1 - 8.9e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KEY70184.1 - 1.4e-11 44.2 7.7 1.4e-11 44.2 7.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KEY70184.1 - 0.00058 19.8 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KEY70184.1 - 0.003 16.7 5.9 0.0045 16.1 5.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KEY70184.1 - 0.0064 16.3 0.1 0.016 15.1 0.0 1.6 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KEY70184.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 KEY70184.1 - 0.016 14.8 0.1 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEY70184.1 - 0.02 15.0 0.2 0.036 14.1 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 KEY70184.1 - 0.043 13.2 0.2 0.48 9.8 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY70184.1 - 0.074 12.8 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 KEY70184.1 - 0.17 10.8 0.4 0.38 9.7 0.4 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 KEY70184.1 - 0.23 10.4 0.2 0.36 9.9 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 KEY70184.1 - 1.7 8.7 2.8 3 7.9 2.8 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain TILa PF12714.7 KEY70184.1 - 2.3 8.3 6.8 1.6 8.8 0.2 2.8 2 1 1 3 3 3 0 TILa domain Fve PF09259.11 KEY70185.1 - 9.8e-42 141.6 0.4 1.1e-41 141.5 0.4 1.0 1 0 0 1 1 1 1 Fungal immunomodulatory protein Fve Nop52 PF05997.12 KEY70186.1 - 0.11 12.2 1.5 0.14 12.0 0.2 1.7 2 0 0 2 2 2 0 Nucleolar protein,Nop52 FAA_hydrolase PF01557.18 KEY70187.1 - 1.1e-54 185.4 0.0 1.9e-54 184.6 0.0 1.3 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KEY70187.1 - 1.9e-33 114.9 0.0 3.9e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Aldo_ket_red PF00248.21 KEY70188.1 - 4.8e-60 203.2 0.0 6e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KEY70189.1 - 1.4e-19 70.5 0.0 2.6e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70189.1 - 7.4e-09 35.3 0.0 2.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY70189.1 - 0.072 13.0 0.1 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KEY70190.1 - 1e-10 41.5 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KEY70190.1 - 3.4e-09 36.0 0.0 1.9e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KEY70190.1 - 0.00018 20.9 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY70190.1 - 0.0021 18.0 0.0 0.027 14.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY70190.1 - 0.013 14.8 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.11 KEY70192.1 - 2.1e-30 106.0 2.6 5.9e-30 104.6 2.6 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 KEY70194.1 - 4e-30 103.9 6.2 7.4e-14 51.8 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEY70194.1 - 1.9e-27 94.3 0.2 1.4e-07 31.1 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70194.1 - 1.8e-10 40.1 1.5 0.012 15.5 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70194.1 - 5.1e-10 38.7 1.2 0.063 13.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70194.1 - 3.1e-09 36.3 0.3 0.018 14.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY70194.1 - 2.7e-05 24.0 0.4 0.8 10.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY70194.1 - 0.00011 22.6 1.0 0.91 10.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEY70194.1 - 0.00012 21.4 0.2 0.037 13.2 0.0 2.4 1 1 0 2 2 2 2 NB-ARC domain TPR_14 PF13428.6 KEY70194.1 - 0.00049 20.7 0.8 7 7.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KEY70194.1 - 0.00054 19.9 4.7 0.99 9.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY70194.1 - 0.00062 19.9 0.9 0.027 14.7 0.2 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEY70194.1 - 0.0018 18.5 0.3 0.73 10.4 0.0 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY70194.1 - 0.0033 18.0 1.1 8.2 7.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY70194.1 - 0.032 14.8 0.0 0.032 14.8 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KEY70194.1 - 0.033 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KEY70194.1 - 0.067 13.8 0.0 0.067 13.8 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 KEY70195.1 - 1.8e-12 47.4 0.0 2.5e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_3_C PF01915.22 KEY70196.1 - 1.4e-35 123.1 0.0 3.6e-35 121.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY70196.1 - 2.3e-30 106.0 0.0 2e-29 103.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY70196.1 - 4.1e-18 65.2 0.1 9.3e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.18 KEY70197.1 - 1.2e-08 34.9 6.6 3.1e-08 33.6 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY70197.1 - 0.0076 15.3 0.4 0.014 14.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_3 PF13302.7 KEY70198.1 - 6.1e-30 104.7 0.0 7.6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY70198.1 - 5.5e-10 39.5 0.0 7.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KEY70198.1 - 8.2e-07 29.3 0.0 1.1e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEY70198.1 - 3.2e-05 23.7 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KEY70199.1 - 2.6e-24 85.8 0.0 2.7e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEY70199.1 - 2.1e-14 53.7 0.0 7.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KEY70199.1 - 0.00051 20.2 0.0 0.34 11.0 0.0 3.3 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KEY70199.1 - 0.017 15.3 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FGE-sulfatase PF03781.16 KEY70200.1 - 1.4e-49 169.0 1.4 1.9e-49 168.6 1.4 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 MFS_1 PF07690.16 KEY70201.1 - 3.6e-34 118.3 24.5 3.6e-34 118.3 24.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70201.1 - 2.3e-07 30.1 8.6 2.3e-07 30.1 8.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Proton_antipo_N PF00662.20 KEY70201.1 - 0.58 10.3 5.1 0.48 10.5 0.5 2.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Cu-oxidase_3 PF07732.15 KEY70202.1 - 1.2e-38 131.8 3.6 1.3e-38 131.7 1.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEY70202.1 - 1.1e-36 125.6 11.5 7.9e-28 96.9 0.6 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KEY70202.1 - 1.6e-18 67.3 0.1 2.4e-11 44.0 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Ferric_reduct PF01794.19 KEY70203.1 - 7.2e-19 68.1 15.5 1.6e-18 67.0 15.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEY70203.1 - 1.9e-06 27.9 0.0 8.1e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KEY70203.1 - 4e-05 23.8 0.4 0.0057 16.8 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Amino_oxidase PF01593.24 KEY70204.1 - 1.8e-51 175.9 0.2 2.2e-51 175.5 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY70204.1 - 2.1e-13 50.3 0.1 3.3e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY70204.1 - 1.3e-07 31.0 0.5 2.8e-07 30.0 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY70204.1 - 4.1e-07 29.9 1.7 1.1e-06 28.4 1.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY70204.1 - 9.7e-07 27.8 1.7 9.7e-05 21.2 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KEY70204.1 - 1.9e-06 27.5 0.2 3e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY70204.1 - 2.2e-06 27.1 0.2 3.7e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEY70204.1 - 2e-05 24.0 0.2 0.0015 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY70204.1 - 3e-05 23.4 1.5 0.1 11.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY70204.1 - 0.00013 21.4 0.5 0.00023 20.5 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KEY70204.1 - 0.00041 19.6 0.8 0.0088 15.2 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KEY70204.1 - 0.0017 18.9 0.3 0.0017 18.9 0.3 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY70204.1 - 0.0017 17.4 0.4 0.22 10.5 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY70204.1 - 0.12 12.4 4.1 3.2 7.7 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.8 KEY70205.1 - 4.4e-32 111.3 0.0 5.6e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Synapsin_N PF10581.9 KEY70205.1 - 0.038 14.0 0.3 0.071 13.1 0.3 1.4 1 0 0 1 1 1 0 Synapsin N-terminal Zn_clus PF00172.18 KEY70208.1 - 4.9e-09 36.2 12.8 8.8e-09 35.3 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY70208.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain rpo132 PF12415.8 KEY70208.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase AAA_lid_3 PF17862.1 KEY70209.1 - 0.0055 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Abhydrolase_4 PF08386.10 KEY70210.1 - 4.7e-17 62.0 0.0 1.6e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY70210.1 - 1.5e-13 51.0 0.0 1.3e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KEY70211.1 - 4.9e-30 104.6 45.6 7.9e-30 104.0 45.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70211.1 - 5.1e-08 32.2 13.6 5.1e-08 32.2 13.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KEY70211.1 - 0.0032 15.8 2.3 0.0032 15.8 2.3 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CAAD PF14159.6 KEY70211.1 - 0.02 14.7 0.2 0.1 12.5 0.2 2.2 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3980 PF13140.6 KEY70211.1 - 0.52 10.8 0.1 0.52 10.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3980) DUF4385 PF14328.6 KEY70212.1 - 3.9e-56 189.2 1.9 4.9e-56 188.9 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) HET PF06985.11 KEY70213.1 - 2.1e-25 89.8 0.1 2.5e-21 76.5 0.1 3.1 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2334 PF10096.9 KEY70213.1 - 0.044 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Peptidase_S8 PF00082.22 KEY70214.1 - 4.9e-46 157.4 1.1 1e-45 156.3 1.1 1.5 1 0 0 1 1 1 1 Subtilase family bacHORMA_2 PF18173.1 KEY70214.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 AAA PF00004.29 KEY70215.1 - 6.1e-17 62.3 0.0 1.2e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY70215.1 - 0.0021 18.5 0.4 0.0094 16.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KEY70215.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KEY70215.1 - 0.031 14.6 0.0 0.13 12.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain Zot PF05707.12 KEY70215.1 - 0.042 13.5 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Aminotran_1_2 PF00155.21 KEY70216.1 - 2.4e-70 237.5 0.0 2.8e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ATP-synt_S1 PF05827.12 KEY70218.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Pkinase PF00069.25 KEY70220.1 - 7.1e-73 245.2 0.0 9.3e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70220.1 - 2.4e-37 128.6 0.0 3.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY70220.1 - 7.2e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Lectin_leg-like PF03388.13 KEY70221.1 - 1.1e-60 204.8 0.0 1.6e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KEY70221.1 - 2.5e-05 23.9 0.0 0.053 13.0 0.0 2.7 2 1 0 3 3 3 2 Legume lectin domain ATG27 PF09451.10 KEY70221.1 - 0.052 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 KEY70222.1 - 5.6e-20 70.7 3.3 7e-20 70.4 3.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2040 PF09745.9 KEY70223.1 - 3.9e-37 127.0 23.2 3.9e-37 127.0 23.2 3.7 2 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF3439 PF11921.8 KEY70223.1 - 0.0048 16.9 3.7 0.011 15.7 3.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) LysM PF01476.20 KEY70224.1 - 0.00018 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 KEY70224.1 - 0.00085 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain Prok-RING_4 PF14447.6 KEY70224.1 - 0.15 12.0 8.6 0.28 11.1 8.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MMS1_N PF10433.9 KEY70225.1 - 7.2e-156 519.6 0.0 1.3e-155 518.7 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEY70225.1 - 3.4e-100 335.5 0.0 1.4e-99 333.5 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KEY70225.1 - 0.045 14.0 0.0 1.5 9.2 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-Mss51 PF13824.6 KEY70226.1 - 4.8e-27 93.8 8.7 8.9e-27 93.0 8.7 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KEY70226.1 - 0.0086 16.1 1.8 0.0086 16.1 1.8 2.1 2 0 0 2 2 2 1 MYND finger YebG PF07130.12 KEY70226.1 - 0.13 12.2 0.0 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 YebG protein PXA PF02194.15 KEY70227.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.16 KEY70228.1 - 3.8e-09 36.5 0.1 1e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KEY70228.1 - 9.2e-07 28.4 0.2 1.6e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KEY70228.1 - 0.0024 17.8 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KEY70228.1 - 0.014 15.2 0.1 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 KEY70228.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.16 KEY70228.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 KEY70228.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PTAC PF06130.12 KEY70228.1 - 0.16 12.1 0.1 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Phosphate propanoyltransferase HTH_Tnp_4 PF13613.6 KEY70228.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MMR_HSR1_Xtn PF16897.5 KEY70229.1 - 2.4e-41 140.0 0.2 4.6e-40 135.9 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KEY70229.1 - 6.4e-23 80.6 0.1 1.3e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KEY70229.1 - 4.9e-20 71.7 0.0 1e-19 70.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY70229.1 - 3.7e-09 36.3 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEY70229.1 - 0.0002 21.5 0.0 0.049 13.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KEY70229.1 - 0.0012 18.4 0.2 6.8 6.2 0.0 3.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KEY70229.1 - 0.012 14.7 0.1 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KEY70229.1 - 0.029 14.3 0.1 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase CBS PF00571.28 KEY70229.1 - 0.087 13.3 0.1 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 CBS domain AIG1 PF04548.16 KEY70229.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Ank_2 PF12796.7 KEY70230.1 - 6.3e-20 71.6 0.0 4.1e-13 49.7 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY70230.1 - 1.7e-13 50.8 0.0 1.1e-07 32.3 0.1 5.0 3 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY70230.1 - 1.9e-12 46.2 0.2 0.00034 20.8 0.1 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KEY70230.1 - 9e-12 44.9 2.0 0.00021 21.6 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KEY70230.1 - 4.7e-10 39.5 0.8 0.00012 22.3 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Collagen PF01391.18 KEY70230.1 - 0.18 11.6 2.5 0.38 10.5 2.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) 2OG-FeII_Oxy_2 PF13532.6 KEY70231.1 - 0.0031 17.7 0.0 0.27 11.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.16 KEY70232.1 - 4.7e-13 49.4 1.6 4.7e-13 49.4 1.6 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Lig_chan PF00060.26 KEY70232.1 - 4.1 7.2 5.7 8.7 6.2 5.7 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel WSC PF01822.19 KEY70233.1 - 2.7e-36 123.6 27.6 6e-21 74.4 7.0 5.3 5 1 1 6 6 6 2 WSC domain SOG2 PF10428.9 KEY70233.1 - 0.79 8.9 7.0 1.3 8.1 7.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PCI PF01399.27 KEY70234.1 - 5.4e-09 36.5 0.5 3.4e-08 33.9 0.0 2.6 2 0 0 2 2 2 1 PCI domain JSRP PF15312.6 KEY70234.1 - 2.5 8.1 4.1 18 5.3 0.2 3.1 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein ubiquitin PF00240.23 KEY70235.1 - 1.1e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KEY70235.1 - 0.0049 17.5 0.0 0.0078 16.9 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Presenilin PF01080.17 KEY70235.1 - 0.4 9.4 2.3 0.4 9.4 2.3 1.1 1 0 0 1 1 1 0 Presenilin G-gamma PF00631.22 KEY70236.1 - 4e-23 81.2 0.0 5.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 KEY70237.1 - 9.6e-33 112.2 0.0 1.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.28 KEY70238.1 - 3.2e-40 138.8 0.1 4.1e-40 138.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEY70238.1 - 3e-23 82.0 2.0 4.1e-23 81.5 1.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-HC5HC2H_2 PF13832.6 KEY70239.1 - 2.7e-33 114.4 7.1 2.7e-33 114.4 7.1 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KEY70239.1 - 1e-29 103.9 0.4 6.2e-29 101.4 0.1 2.4 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KEY70239.1 - 8.2e-26 90.1 6.4 8.2e-26 90.1 6.4 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KEY70239.1 - 1.1e-14 53.6 2.2 1.1e-14 53.6 2.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KEY70239.1 - 2e-08 34.0 27.0 7.7e-08 32.1 12.8 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KEY70239.1 - 0.0082 15.8 2.0 0.0082 15.8 2.0 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain LRR_4 PF12799.7 KEY70240.1 - 9.4e-15 54.5 3.3 0.00082 19.7 0.7 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY70240.1 - 1.3e-12 47.2 9.8 2.8e-08 33.4 2.6 3.3 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KEY70240.1 - 0.00089 19.5 5.9 36 5.5 0.3 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KEY70240.1 - 0.0052 16.7 9.3 7.2 6.9 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 KEY70240.1 - 0.0057 16.2 0.2 0.014 14.9 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat RAP1 PF07218.11 KEY70240.1 - 2.6 6.2 6.0 4.9 5.3 6.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gas_vesicle_C PF01304.17 KEY70241.1 - 0.31 11.1 2.3 0.55 10.3 2.3 1.4 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Biotin_lipoyl PF00364.22 KEY70242.1 - 5.1e-17 61.5 2.4 9.3e-17 60.6 2.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEY70242.1 - 6.3e-10 39.2 0.7 2e-09 37.6 0.2 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KEY70242.1 - 0.00045 20.0 0.0 0.0058 16.4 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KEY70242.1 - 0.071 13.8 0.0 0.19 12.5 0.0 1.8 1 1 0 1 1 1 0 HlyD family secretion protein YqfD PF06898.11 KEY70242.1 - 0.17 10.7 0.2 0.33 9.8 0.2 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD CoA_transf_3 PF02515.17 KEY70243.1 - 1.9e-34 119.4 0.0 3.4e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 KEY70244.1 - 3.2e-18 65.7 0.0 5.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70244.1 - 5.4e-08 32.8 12.1 1.2e-07 31.8 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KEY70245.1 - 4.5e-50 169.6 0.0 6.1e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEY70245.1 - 2.3e-26 91.4 0.0 4.6e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEY70245.1 - 0.00023 21.4 0.0 0.015 15.6 0.0 2.8 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain OPT PF03169.15 KEY70246.1 - 3.6e-160 534.6 47.1 1.4e-92 311.3 20.0 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein ketoacyl-synt PF00109.26 KEY70247.1 - 1.9e-60 204.6 5.6 8.8e-60 202.4 1.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY70247.1 - 1.8e-36 124.7 1.9 4.3e-36 123.5 1.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 KEY70247.1 - 5.7e-34 117.2 0.1 1.2e-33 116.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.23 KEY70247.1 - 1.8e-05 24.2 1.7 0.0024 17.3 0.2 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEY70247.1 - 0.069 12.8 4.3 0.08 12.6 0.3 2.9 2 2 0 3 3 3 0 Thiolase, C-terminal domain DHFR_1 PF00186.19 KEY70248.1 - 2.5e-32 111.8 0.0 4.7e-32 110.9 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.20 KEY70248.1 - 1.3e-15 57.7 0.0 2.9e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Sugarporin_N PF11471.8 KEY70248.1 - 0.098 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension adh_short PF00106.25 KEY70249.1 - 2.5e-29 102.1 0.6 1.7e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70249.1 - 5.6e-24 85.0 0.4 6.9e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY70249.1 - 3.8e-05 23.7 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY70249.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KEY70249.1 - 0.097 12.0 0.0 0.42 9.9 0.0 1.9 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KEY70249.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA PF00004.29 KEY70250.1 - 2.7e-49 167.0 0.0 4.6e-42 143.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY70250.1 - 2.8e-09 36.7 0.5 8.2e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KEY70250.1 - 6.1e-08 33.2 0.1 0.00072 20.0 0.3 3.5 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KEY70250.1 - 9.6e-07 28.7 0.0 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KEY70250.1 - 2.3e-05 24.6 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEY70250.1 - 0.0013 19.1 0.1 0.056 13.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEY70250.1 - 0.0019 18.2 0.0 0.012 15.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEY70250.1 - 0.0019 18.6 0.0 0.031 14.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KEY70250.1 - 0.005 17.0 2.4 0.032 14.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KEY70250.1 - 0.0055 17.2 0.1 0.037 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEY70250.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KEY70250.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KEY70250.1 - 0.029 14.6 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KEY70250.1 - 0.049 13.7 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEY70250.1 - 0.063 12.7 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KEY70250.1 - 0.088 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 KEY70250.1 - 0.094 12.5 0.0 8.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein NACHT PF05729.12 KEY70250.1 - 0.11 12.3 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_7 PF12775.7 KEY70250.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEY70250.1 - 0.41 11.1 1.8 1.1 9.8 0.0 2.7 4 0 0 4 4 1 0 ABC transporter AAA_11 PF13086.6 KEY70250.1 - 0.71 9.6 0.0 0.71 9.6 0.0 3.7 3 1 0 3 3 2 0 AAA domain tRNA-synt_1e PF01406.19 KEY70251.1 - 3.1e-24 85.9 0.0 5.4e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Carb_anhydrase PF00194.21 KEY70252.1 - 2.3e-33 115.8 0.1 3.8e-33 115.1 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Gemini_AL3 PF01407.17 KEY70252.1 - 0.032 14.1 0.1 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Geminivirus AL3 protein Dus PF01207.17 KEY70254.1 - 2.6e-61 207.4 0.0 5.9e-61 206.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KEY70254.1 - 0.031 13.5 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF3752 PF12572.8 KEY70254.1 - 2.9 8.4 6.8 8.9 6.8 6.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Ifi-6-16 PF06140.13 KEY70255.1 - 1.2e-07 31.5 32.4 1.2e-07 31.5 31.5 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family CPSF100_C PF13299.6 KEY70255.1 - 0.024 14.8 0.4 0.035 14.3 0.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LapA_dom PF06305.11 KEY70255.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MA3 PF02847.17 KEY70256.1 - 1.3e-23 83.1 0.0 4.8e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KEY70256.1 - 8.2e-12 45.2 0.3 2.5e-11 43.6 0.2 1.9 2 0 0 2 2 2 1 MIF4G domain Corona_nucleoca PF00937.18 KEY70256.1 - 0.87 8.6 8.3 1.5 7.8 8.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Transformer PF06495.11 KEY70256.1 - 1.4 9.0 20.9 0.84 9.7 13.6 2.3 2 0 0 2 2 2 0 Fruit fly transformer protein CDC45 PF02724.14 KEY70256.1 - 2.2 6.4 12.9 0.45 8.7 6.4 2.2 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 KEY70256.1 - 6.2 4.8 11.9 12 3.8 11.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi DPM2 PF07297.12 KEY70257.1 - 2.1e-30 104.8 1.3 2.4e-30 104.7 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KEY70257.1 - 0.0007 19.5 1.2 0.00077 19.4 1.2 1.1 1 0 0 1 1 1 1 PIG-P LapA_dom PF06305.11 KEY70257.1 - 0.0022 17.7 0.3 0.0022 17.7 0.3 1.5 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KEY70257.1 - 0.0043 17.1 1.4 0.0051 16.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) SoxD PF04267.12 KEY70259.1 - 0.064 13.4 0.5 0.29 11.3 0.4 1.9 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family PHD PF00628.29 KEY70260.1 - 1.9e-06 27.6 7.0 3.2e-06 26.9 7.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KEY70260.1 - 0.011 16.3 0.0 0.03 14.9 0.0 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KEY70260.1 - 0.08 13.2 1.2 0.16 12.2 1.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KEY70260.1 - 0.43 10.2 1.3 0.71 9.5 1.3 1.4 1 0 0 1 1 1 0 PHD-finger Bactofilin PF04519.13 KEY70261.1 - 2.6e-06 27.7 0.0 0.049 13.9 0.0 2.1 1 1 1 2 2 2 2 Polymer-forming cytoskeletal FapA PF03961.13 KEY70261.1 - 1.5e-05 23.8 0.1 3.2e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Flagellar Assembly Protein A MinC_C PF03775.16 KEY70261.1 - 0.00091 19.2 0.2 0.39 10.7 0.0 2.6 1 1 2 3 3 3 3 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.11 KEY70261.1 - 0.033 14.3 0.0 35 4.5 0.0 3.0 1 1 2 3 3 3 0 Domain of Unknown Function (DUF748) zf-C2H2 PF00096.26 KEY70263.1 - 0.015 15.7 3.1 0.046 14.2 3.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.15 KEY70263.1 - 0.17 12.0 2.3 0.33 11.0 2.3 1.5 1 0 0 1 1 1 0 BED zinc finger DUF3602 PF12223.8 KEY70264.1 - 2.9e-09 37.4 14.0 5.8e-07 30.0 5.9 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Pam16 PF03656.13 KEY70265.1 - 8.4e-07 29.1 0.0 9.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KEY70265.1 - 2.9e-05 24.1 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KEY70265.1 - 0.028 14.0 1.6 0.057 13.1 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Ku_PK_bind PF08785.11 KEY70267.1 - 4.8e-36 123.5 0.0 9.8e-36 122.5 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KEY70267.1 - 2.6e-28 99.2 0.0 4.5e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KEY70267.1 - 2.1e-13 50.6 0.3 3.6e-13 49.8 0.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KEY70267.1 - 0.027 14.7 0.1 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Ku_C PF03730.14 KEY70267.1 - 0.091 13.5 0.1 0.27 11.9 0.1 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm DUF4149 PF13664.6 KEY70268.1 - 9.1e-24 83.7 3.4 9.1e-24 83.7 3.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KEY70268.1 - 0.0035 17.7 1.0 0.0049 17.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3781 PF12636.7 KEY70268.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF2570 PF10828.8 KEY70269.1 - 0.082 12.7 1.4 0.12 12.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Hydrolase_6 PF13344.6 KEY70270.1 - 1.8e-24 85.8 0.0 2.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY70270.1 - 4.5e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY70270.1 - 2.3e-13 50.9 0.0 6.2e-07 29.9 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEY70270.1 - 0.00027 21.1 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF1295 PF06966.12 KEY70271.1 - 3.4e-29 102.0 19.3 3.6e-26 92.1 19.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KEY70271.1 - 0.13 12.7 1.1 0.65 10.5 0.0 2.6 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 KEY70272.1 - 3.6e-104 349.1 0.0 1.7e-99 333.7 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KEY70272.1 - 1.6e-18 66.8 0.0 3.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.9 KEY70273.1 - 3e-37 126.5 0.0 4.8e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.26 KEY70274.1 - 5.1e-07 29.8 20.3 1.8e-05 24.9 3.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY70274.1 - 4.6e-05 23.9 2.5 4.6e-05 23.9 2.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY70274.1 - 7.1e-05 23.1 4.2 7.1e-05 23.1 4.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KEY70274.1 - 0.00068 19.9 1.1 0.00068 19.9 1.1 2.3 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KEY70274.1 - 0.0016 18.7 4.7 0.005 17.1 4.7 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KEY70274.1 - 0.0026 18.1 3.4 0.14 12.6 0.8 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KEY70274.1 - 0.015 15.3 2.3 0.031 14.3 2.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger MPP6 PF10175.9 KEY70274.1 - 0.079 13.5 4.5 0.19 12.2 4.5 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 FOXP-CC PF16159.5 KEY70274.1 - 0.14 12.8 8.4 0.34 11.6 0.8 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KEY70274.1 - 0.61 10.8 7.7 0.099 13.4 3.3 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 KEY70274.1 - 0.79 10.1 7.0 2.8 8.3 5.3 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3915 PF13054.6 KEY70274.1 - 2.1 8.4 4.5 4.4 7.3 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF629 PF04780.12 KEY70274.1 - 2.5 6.5 6.3 2.2 6.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_aberr PF17017.5 KEY70274.1 - 2.6 8.2 4.6 6.5 6.9 4.6 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KEY70274.1 - 6.5 6.8 7.0 0.59 10.1 1.8 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Fungal_trans PF04082.18 KEY70276.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70276.1 - 1.7e-07 31.2 11.0 1.7e-07 31.2 11.0 3.4 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1451 PF07295.11 KEY70276.1 - 0.45 10.5 3.3 0.98 9.5 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain EphA2_TM PF14575.6 KEY70277.1 - 0.067 14.1 0.0 0.092 13.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PUF PF00806.19 KEY70278.1 - 1.7e-52 172.3 6.3 1.3e-07 30.9 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KEY70278.1 - 0.0014 19.0 2.9 4.1 7.8 0.0 3.7 2 2 2 4 4 4 2 CPL (NUC119) domain MgtE_N PF03448.17 KEY70278.1 - 0.11 13.2 2.2 3.1 8.4 0.0 3.5 2 2 1 3 3 3 0 MgtE intracellular N domain DUF1640 PF07798.11 KEY70279.1 - 3.3e-46 157.5 4.5 4.9e-46 157.0 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KEY70279.1 - 0.17 11.9 2.6 0.35 10.9 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 KEY70280.1 - 3.9e-33 114.4 7.6 8e-33 113.4 7.6 1.6 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 KEY70280.1 - 0.77 9.7 4.3 0.21 11.5 0.6 2.0 2 0 0 2 2 2 0 Stathmin family PXA PF02194.15 KEY70281.1 - 2.4e-32 112.4 0.4 4.5e-32 111.5 0.4 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KEY70281.1 - 8.5e-21 74.6 0.5 2.9e-20 72.9 0.0 2.2 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KEY70281.1 - 6.7e-08 32.5 0.1 2.3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 PX domain RIB43A PF05914.12 KEY70281.1 - 0.016 14.0 2.7 0.023 13.4 2.7 1.2 1 0 0 1 1 1 0 RIB43A HEPN_SAV_6107 PF18726.1 KEY70281.1 - 0.24 11.9 1.7 34 5.0 1.5 2.6 2 0 0 2 2 2 0 SAV_6107-like HEPN PC4 PF02229.16 KEY70282.1 - 1.7e-25 88.4 0.2 2.8e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) KIF1B PF12423.8 KEY70282.1 - 0.11 12.9 1.3 0.21 12.0 0.1 2.1 3 0 0 3 3 3 0 Kinesin protein 1B YqfQ PF14181.6 KEY70282.1 - 0.85 9.8 5.2 0.21 11.8 0.4 1.9 2 0 0 2 2 2 0 YqfQ-like protein MFS_1 PF07690.16 KEY70283.1 - 1e-31 110.1 51.4 8.2e-28 97.3 32.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70283.1 - 7.1e-19 68.0 24.6 2.4e-14 53.1 5.8 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter Ctr PF04145.15 KEY70283.1 - 0.16 12.6 5.9 0.098 13.3 1.5 2.6 2 1 0 2 2 2 0 Ctr copper transporter family RyR PF02026.16 KEY70283.1 - 0.2 11.8 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 RyR domain DnaJ PF00226.31 KEY70284.1 - 3.3e-11 43.1 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CDH-cyt PF16010.5 KEY70285.1 - 2.5e-18 66.4 0.0 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KEY70285.1 - 7.7e-10 39.0 14.9 2.2e-09 37.5 14.9 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KEY70285.1 - 0.00012 21.8 11.9 0.00012 21.8 10.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 KEY70285.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 DOMON domain DUF2157 PF09925.9 KEY70285.1 - 0.41 10.4 17.2 0.063 13.1 2.4 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) RseC_MucC PF04246.12 KEY70285.1 - 5.8 6.9 10.2 0.35 10.8 1.9 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4079 PF13301.6 KEY70285.1 - 9 6.5 15.3 9.7 6.3 1.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 KEY70286.1 - 3e-27 95.5 23.8 3e-27 95.5 23.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY70286.1 - 6.4e-05 22.0 1.9 6.4e-05 22.0 1.9 2.7 2 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 KEY70286.1 - 0.00044 19.2 5.9 0.00044 19.2 5.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KEY70286.1 - 0.0075 14.7 1.3 0.0075 14.7 1.3 2.4 2 1 0 2 2 2 2 Transmembrane secretion effector Cation_ATPase_C PF00689.21 KEY70286.1 - 0.23 11.1 8.7 3.9 7.1 1.0 2.9 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Ureidogly_lyase PF04115.12 KEY70287.1 - 1.2e-52 178.5 0.0 1.3e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase 2_5_RNA_ligase2 PF13563.6 KEY70288.1 - 0.034 14.1 0.1 0.3 11.0 0.1 2.1 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KEY70288.1 - 0.048 13.8 0.1 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase Ribosomal_L44 PF00935.19 KEY70289.1 - 2.3e-36 124.1 12.9 3.4e-36 123.5 12.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Coatomer_E PF04733.14 KEY70290.1 - 8.6e-63 212.4 2.5 9.9e-63 212.2 2.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KEY70290.1 - 7.6e-11 42.4 12.9 0.00047 20.6 1.1 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY70290.1 - 5.4e-07 29.7 0.1 0.34 11.2 0.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KEY70290.1 - 7.3e-05 22.7 0.3 1 9.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY70290.1 - 0.00021 21.5 8.1 0.036 14.3 1.1 5.1 3 3 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70290.1 - 0.00024 20.8 0.0 0.14 12.0 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY70290.1 - 0.00035 21.1 12.5 0.037 14.9 0.9 5.5 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70290.1 - 0.00049 20.0 8.0 0.01 15.9 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Type_III_YscG PF09477.10 KEY70290.1 - 0.00065 19.7 2.4 0.26 11.4 0.0 3.5 1 1 1 3 3 3 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.6 KEY70290.1 - 0.0042 17.7 8.9 0.87 10.3 0.2 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEY70290.1 - 0.0063 16.2 3.5 0.037 13.7 0.8 3.5 4 0 0 4 4 4 1 TPR repeat TPR_6 PF13174.6 KEY70290.1 - 0.016 15.8 1.2 1.9 9.3 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY70290.1 - 0.31 11.0 1.9 48 4.0 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY70290.1 - 3.3 8.6 15.4 2.8 8.8 0.3 5.3 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEY70290.1 - 3.7 7.8 6.6 1.1 9.5 0.6 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat MBF1 PF08523.10 KEY70292.1 - 6e-24 84.3 0.6 1.2e-23 83.3 0.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KEY70292.1 - 7.5e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEY70292.1 - 0.00025 21.3 0.0 0.00058 20.2 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MRP-L27 PF09809.9 KEY70292.1 - 0.0067 16.2 0.3 0.01 15.6 0.3 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 HTH_24 PF13412.6 KEY70292.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GFA PF04828.14 KEY70293.1 - 3.3e-25 88.2 0.0 5e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KEY70293.1 - 0.15 12.1 3.3 1.1 9.3 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon Sporozoite_P67 PF05642.11 KEY70294.1 - 0.00042 18.6 4.7 0.00046 18.4 4.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4690 PF15756.5 KEY70294.1 - 0.036 14.7 5.5 0.036 14.7 5.5 2.0 1 1 1 2 2 2 0 Small Novel Rich in Cartilage PS-DH PF14765.6 KEY70295.1 - 0.085 12.1 1.0 0.15 11.3 1.0 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase SpoU_methylase PF00588.19 KEY70296.1 - 7.4e-23 81.3 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KEY70296.1 - 3.9e-13 49.5 0.0 6.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 KEY70297.1 - 5.9e-67 224.5 13.9 1.1e-66 223.7 13.9 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KEY70297.1 - 4.6e-48 163.7 0.0 8.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY70297.1 - 1e-17 64.5 0.0 2.5e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KEY70297.1 - 6.9e-09 35.5 2.1 3.5e-05 23.6 0.8 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 KEY70297.1 - 6.9e-07 28.7 2.3 2.2e-06 27.1 2.3 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KEY70297.1 - 1.8e-06 27.7 17.8 1.3e-05 25.0 4.9 3.2 2 1 1 3 3 3 2 PHD-finger ResIII PF04851.15 KEY70297.1 - 2.2e-05 24.5 0.0 6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 KEY70297.1 - 0.00011 21.7 0.6 0.00011 21.7 0.6 2.6 3 0 0 3 3 3 1 PHD-finger DUF1087 PF06465.13 KEY70297.1 - 0.014 15.4 0.1 0.2 11.7 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) SnAC PF14619.6 KEY70297.1 - 0.027 15.1 0.4 0.13 12.9 0.4 2.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Prok-RING_1 PF14446.6 KEY70297.1 - 0.097 12.6 10.3 0.021 14.7 2.6 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SUR7 PF06687.12 KEY70299.1 - 5.2e-33 114.5 10.3 6.7e-33 114.1 10.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family VIT1 PF01988.19 KEY70299.1 - 1.5 8.7 7.6 2.5 7.9 7.6 1.2 1 0 0 1 1 1 0 VIT family E_Pc_C PF06752.12 KEY70300.1 - 0.00043 20.5 1.5 0.00066 19.9 1.5 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus DUF4687 PF15747.5 KEY70301.1 - 0.015 15.8 0.3 0.021 15.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) DUF3433 PF11915.8 KEY70302.1 - 7.2e-36 122.5 13.8 1.4e-21 76.7 2.9 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF2569 PF10754.9 KEY70302.1 - 7.2 7.0 13.6 0.73 10.3 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) TRP PF06011.12 KEY70303.1 - 9.2e-160 532.0 35.3 1.1e-159 531.7 35.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEY70303.1 - 1.6e-38 132.2 0.2 2.7e-38 131.5 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KEY70303.1 - 0.0015 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 ML domain AIM24 PF01987.17 KEY70306.1 - 3.7e-50 170.5 0.5 4.5e-50 170.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 zf-C2H2 PF00096.26 KEY70308.1 - 0.00053 20.3 11.4 0.031 14.7 1.0 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY70308.1 - 0.0047 17.6 18.4 0.01 16.6 1.4 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY70308.1 - 0.0096 16.2 3.9 1 9.7 0.6 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KEY70308.1 - 0.29 11.8 5.6 0.41 11.3 1.5 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 KEY70308.1 - 0.46 11.1 11.4 7.5 7.3 0.8 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF629 PF04780.12 KEY70308.1 - 3 6.3 6.2 1.7 7.1 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KEY70310.1 - 1.8e-06 28.1 42.2 0.0029 18.0 1.0 6.9 5 1 1 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY70310.1 - 0.011 16.6 49.5 0.025 15.4 0.9 7.4 6 1 1 7 7 7 0 C2H2-type zinc finger THP2 PF09432.10 KEY70310.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Tho complex subunit THP2 YdjO PF14169.6 KEY70310.1 - 0.24 11.2 4.5 0.25 11.1 1.7 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-met PF12874.7 KEY70310.1 - 1.1 9.7 13.5 4 8.0 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Cyt-b5 PF00173.28 KEY70311.1 - 1.2e-13 50.9 0.1 1.5e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.6 KEY70312.1 - 3.8e-10 39.9 0.0 0.0079 16.5 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70312.1 - 8.7e-08 31.7 0.0 0.029 14.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70312.1 - 3.6e-07 29.8 0.1 0.0084 16.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70312.1 - 0.00021 21.1 0.0 0.84 9.8 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat FANCI_S1 PF14675.6 KEY70312.1 - 0.2 11.2 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 bZIP_1 PF00170.21 KEY70313.1 - 2.1e-06 27.8 9.9 4.8e-06 26.6 9.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KEY70313.1 - 0.011 15.5 2.9 0.016 14.9 2.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KEY70313.1 - 0.012 15.7 5.6 0.012 15.7 5.6 1.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF722 PF05263.11 KEY70313.1 - 0.07 13.3 0.5 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) bZIP_Maf PF03131.17 KEY70313.1 - 0.12 12.9 12.2 0.26 11.8 12.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Cut8 PF08559.10 KEY70314.1 - 4.1e-76 255.8 0.0 6.1e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Rad52_Rad22 PF04098.15 KEY70314.1 - 8.6e-57 191.4 0.0 1.3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 KEY70315.1 - 3.5e-16 58.8 0.2 3.2e-09 36.5 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KEY70315.1 - 0.005 16.7 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KEY70315.1 - 0.0059 16.7 0.1 0.24 11.5 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KEY70315.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEY70315.1 - 0.08 13.0 1.6 0.25 11.4 0.3 2.4 2 0 0 2 2 2 0 RNA binding motif DSBA PF01323.20 KEY70316.1 - 5.4e-11 42.6 1.0 6.5e-11 42.4 1.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-CCHC PF00098.23 KEY70318.1 - 1.2e-05 25.2 31.1 0.11 12.6 0.9 5.5 5 0 0 5 5 5 5 Zinc knuckle ORMDL PF04061.14 KEY70319.1 - 1.3e-58 196.7 4.2 1.6e-58 196.4 4.2 1.1 1 0 0 1 1 1 1 ORMDL family COesterase PF00135.28 KEY70321.1 - 3.1e-79 267.2 0.0 6.3e-79 266.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY70321.1 - 2.1e-05 24.5 0.6 0.00011 22.1 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M1 PF01433.20 KEY70322.1 - 2.7e-81 272.3 1.7 4e-81 271.7 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KEY70322.1 - 1.4e-80 271.2 0.0 4.9e-80 269.4 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KEY70322.1 - 1.7e-48 165.3 1.0 3.2e-48 164.4 1.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KEY70322.1 - 0.00063 19.8 0.2 0.0066 16.4 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2808) DUF45 PF01863.17 KEY70322.1 - 0.039 14.0 0.5 0.16 12.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF45 Tcp11 PF05794.13 KEY70324.1 - 1.8e-96 324.0 0.6 1.8e-96 324.0 0.6 2.1 2 0 0 2 2 2 1 T-complex protein 11 DUF1116 PF06545.11 KEY70324.1 - 0.069 12.6 1.5 0.14 11.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) IQ PF00612.27 KEY70324.1 - 0.2 11.5 1.3 0.78 9.7 1.3 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Y_phosphatase PF00102.27 KEY70325.1 - 2.9e-61 207.0 0.0 5e-53 180.1 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KEY70325.1 - 5.8e-13 49.3 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KEY70325.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CCAP PF11105.8 KEY70325.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DSPc PF00782.20 KEY70325.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1989 PF09347.10 KEY70326.1 - 9.6e-62 207.5 0.0 1.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.29 KEY70327.1 - 1.4e-43 148.5 0.0 2.2e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY70327.1 - 1.1e-14 53.9 0.0 4.3e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KEY70327.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEY70327.1 - 2.8e-07 30.8 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KEY70327.1 - 5.3e-07 29.5 1.5 1.4e-06 28.2 1.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KEY70327.1 - 4.1e-06 27.3 0.0 0.00011 22.6 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY70327.1 - 4.3e-05 23.8 0.3 0.018 15.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KEY70327.1 - 9.1e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEY70327.1 - 0.00044 20.8 0.1 0.015 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KEY70327.1 - 0.00088 18.9 0.1 0.0032 17.1 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 KEY70327.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KEY70327.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEY70327.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 KEY70327.1 - 0.0063 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KEY70327.1 - 0.0071 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEY70327.1 - 0.0089 15.9 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEY70327.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEY70327.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KEY70327.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEY70327.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KEY70327.1 - 0.024 14.1 0.0 0.093 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KEY70327.1 - 0.025 14.3 0.1 0.064 13.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KEY70327.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KEY70327.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KEY70327.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.9 KEY70327.1 - 0.049 13.9 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_7 PF12775.7 KEY70327.1 - 0.05 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KEY70327.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HR1 PF02185.16 KEY70327.1 - 0.11 12.6 1.0 0.27 11.4 1.0 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_11 PF13086.6 KEY70327.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEY70327.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KEY70327.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Na_Ca_ex PF01699.24 KEY70328.1 - 2.1e-23 83.0 30.3 1.4e-16 60.8 13.4 3.5 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KEY70328.1 - 1.4e-16 60.9 9.1 1.4e-16 60.9 9.1 4.0 2 0 0 2 2 2 1 Inner membrane component domain MFS_1 PF07690.16 KEY70329.1 - 1.3e-13 50.6 42.6 1.3e-13 50.6 42.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Clathrin PF00637.20 KEY70330.1 - 8.4e-25 87.3 1.1 4.2e-22 78.5 0.4 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS CTP_transf_like PF01467.26 KEY70330.1 - 0.00097 19.3 0.0 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like Atg14 PF10186.9 KEY70330.1 - 0.044 12.9 0.1 0.084 12.0 0.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_11 PF13414.6 KEY70330.1 - 0.083 12.6 0.0 0.34 10.6 0.0 2.1 1 0 0 1 1 1 0 TPR repeat p450 PF00067.22 KEY70331.1 - 1.9e-56 191.7 0.0 2.6e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KEY70332.1 - 1.2e-05 25.2 0.0 4e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY70332.1 - 0.082 13.6 0.1 1.9 9.2 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain HATPase_c_3 PF13589.6 KEY70335.1 - 1.2e-16 60.8 0.0 3.9e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KEY70335.1 - 5e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KEY70335.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Striatin PF08232.12 KEY70336.1 - 1.2e-38 133.1 4.4 2.3e-38 132.2 4.4 1.4 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 KEY70336.1 - 2.8e-22 78.6 21.2 9.3e-05 23.1 0.4 7.7 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY70336.1 - 4.5e-05 23.7 0.0 17 5.8 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY70336.1 - 0.19 10.6 0.0 0.91 8.4 0.0 2.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Alg14 PF08660.11 KEY70337.1 - 1.1e-39 136.2 0.0 1.8e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like MRP-S25 PF13741.6 KEY70338.1 - 4.8e-64 216.1 12.6 5.7e-61 206.0 12.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KEY70338.1 - 4e-05 23.9 1.3 8.8e-05 22.8 1.1 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 KEY70339.1 - 3.4e-14 52.8 0.5 0.00011 22.3 0.0 5.0 3 2 2 5 5 5 3 PPR repeat family PPR PF01535.20 KEY70339.1 - 1.1e-12 47.3 3.7 3e-05 24.0 0.0 4.6 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KEY70339.1 - 1.7e-07 31.2 0.1 0.068 13.3 0.0 3.6 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KEY70339.1 - 0.00019 21.0 4.2 0.59 9.9 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KEY70339.1 - 0.0053 16.1 0.4 1.3 8.3 0.1 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP DED PF01335.21 KEY70339.1 - 0.052 13.8 0.0 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Death effector domain COX7C PF02935.16 KEY70340.1 - 1.2e-21 76.8 6.2 1.4e-21 76.5 6.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 KEY70341.1 - 1.5e-84 284.2 0.8 3.4e-84 283.0 0.0 2.1 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 KEY70341.1 - 1e-50 171.6 3.0 2.7e-50 170.2 3.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KEY70341.1 - 2.4e-18 66.5 0.0 6.7e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY70341.1 - 8.4e-07 29.3 0.1 5e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY70341.1 - 1.1e-05 25.5 0.5 7e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KEY70341.1 - 0.005 15.9 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEY70341.1 - 0.024 14.9 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Prp19 PF08606.11 KEY70341.1 - 0.089 12.8 0.5 3.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like DUF2407 PF10302.9 KEY70342.1 - 3.4e-27 95.0 0.0 6.5e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 KEY70342.1 - 1.5e-23 83.5 0.1 2.2e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain Ima1_N PF09779.9 KEY70343.1 - 1.1e-35 123.4 4.9 1.9e-35 122.7 4.9 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Casein_kappa PF00997.18 KEY70343.1 - 0.01 16.0 0.4 0.023 14.8 0.4 1.5 1 0 0 1 1 1 1 Kappa casein DZR PF12773.7 KEY70343.1 - 0.056 13.5 3.2 3 7.9 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon Y_phosphatase2 PF03162.13 KEY70344.1 - 4.3e-44 150.0 0.0 8.8e-44 149.0 0.0 1.4 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KEY70344.1 - 1e-08 35.4 0.1 3.4e-08 33.7 0.1 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KEY70344.1 - 0.00079 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEY70344.1 - 0.003 17.2 0.3 0.0051 16.4 0.3 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Aim19 PF10315.9 KEY70345.1 - 0.0011 19.2 2.4 0.0043 17.3 0.3 2.1 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 Zn_clus PF00172.18 KEY70346.1 - 7.8e-07 29.1 10.9 1.2e-06 28.5 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pho88 PF10032.9 KEY70347.1 - 1.4e-81 272.1 0.3 1.6e-81 272.0 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4345 PF14248.6 KEY70347.1 - 0.0038 17.1 0.3 0.51 10.3 0.0 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4345) DUF1240 PF06836.12 KEY70347.1 - 0.086 13.4 1.5 0.32 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF3796 PF12676.7 KEY70347.1 - 0.12 12.8 0.7 0.25 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) XPA_C PF05181.12 KEY70348.1 - 1.1e-25 89.3 1.7 2.8e-25 88.0 1.7 1.7 1 0 0 1 1 1 1 XPA protein C-terminus zf-C3HC4_3 PF13920.6 KEY70348.1 - 0.089 12.7 7.3 0.044 13.7 4.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FRG1 PF06229.12 KEY70348.1 - 0.58 9.8 5.2 0.18 11.5 1.1 2.0 2 0 0 2 2 2 0 FRG1-like domain GFA PF04828.14 KEY70348.1 - 3.5 8.0 5.9 9.6 6.6 0.0 3.1 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Ras PF00071.22 KEY70349.1 - 4.5e-05 23.1 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 2 Ras family DAO PF01266.24 KEY70350.1 - 1.6e-27 97.0 1.6 2e-27 96.7 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY70350.1 - 0.004 16.4 0.1 0.0067 15.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 KEY70350.1 - 0.0045 15.6 0.1 0.0066 15.0 0.1 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KEY70350.1 - 0.011 15.9 0.1 0.034 14.4 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY70350.1 - 0.047 12.9 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FliT PF05400.13 KEY70350.1 - 0.068 14.0 0.1 1.6 9.6 0.1 2.7 3 0 0 3 3 3 0 Flagellar protein FliT FAD_binding_2 PF00890.24 KEY70350.1 - 0.24 10.4 4.2 0.46 9.5 4.1 1.6 1 1 0 1 1 1 0 FAD binding domain IPK PF03770.16 KEY70352.1 - 2.5e-54 184.2 0.0 4.4e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.7 KEY70354.1 - 1.1e-28 98.7 41.7 4.5e-07 30.1 1.0 9.3 4 1 7 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY70354.1 - 5.7e-14 51.6 48.3 0.00011 21.9 0.2 8.0 5 2 5 10 10 10 6 Leucine rich repeat LRR_9 PF14580.6 KEY70354.1 - 4e-10 39.5 11.8 0.0018 17.8 0.4 4.7 2 2 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KEY70354.1 - 1.4e-06 27.9 17.0 2.9 8.2 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich repeat NUP50 PF08911.11 KEY70354.1 - 0.19 12.4 3.2 0.48 11.1 1.4 2.8 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) LRR_1 PF00560.33 KEY70354.1 - 9.4 7.2 30.6 22 6.1 1.6 9.7 9 3 0 9 9 9 0 Leucine Rich Repeat Aconitase PF00330.20 KEY70355.1 - 1.4e-109 367.2 0.7 1.2e-108 364.1 0.7 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEY70355.1 - 4.2e-21 75.6 0.0 7.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain RabGAP-TBC PF00566.18 KEY70356.1 - 4.5e-47 160.5 0.0 7.2e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Filament PF00038.21 KEY70356.1 - 0.081 12.5 4.4 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein PIG-L PF02585.17 KEY70356.1 - 1.5 9.5 3.5 3 8.5 0.2 2.7 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase ECH_1 PF00378.20 KEY70357.1 - 1.2e-08 34.6 0.0 8.5e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DDE_Tnp_1_7 PF13843.6 KEY70358.1 - 5.2e-19 68.8 0.0 5.3e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Dimer_Tnp_hAT PF05699.14 KEY70359.1 - 1e-18 66.9 0.1 3.7e-18 65.1 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tyrosinase PF00264.20 KEY70360.1 - 2.8e-50 171.6 4.4 4.2e-50 171.1 4.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KEY70360.1 - 4.2e-27 95.2 0.0 7.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpb2_6 PF00562.28 KEY70361.1 - 6.8e-113 377.7 0.1 9.1e-113 377.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEY70361.1 - 1.1e-33 116.5 0.0 1.7e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KEY70361.1 - 5.9e-28 96.8 0.0 1.7e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KEY70361.1 - 6.9e-24 84.5 0.0 1.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KEY70361.1 - 1.3e-23 82.7 0.0 3.8e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KEY70361.1 - 6.8e-16 58.4 0.0 1.4e-14 54.2 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rpr2 PF04032.16 KEY70361.1 - 0.19 12.0 0.8 0.4 11.0 0.8 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.21 KEY70362.1 - 6.8e-29 100.5 0.0 7.3e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KEY70362.1 - 7.7e-13 48.4 0.0 9.1e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY70362.1 - 1.2e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KEY70362.1 - 2.9e-05 23.5 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KEY70362.1 - 0.0039 16.4 0.1 0.0049 16.1 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 KEY70362.1 - 0.008 15.7 0.0 0.0093 15.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KEY70362.1 - 0.048 13.7 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ACT PF01842.25 KEY70362.1 - 0.098 12.5 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 ACT domain Beta_elim_lyase PF01212.21 KEY70363.1 - 1.4e-63 214.9 0.0 1.8e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KEY70363.1 - 0.001 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEY70363.1 - 0.0037 16.3 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEY70363.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family tRNA-synt_2 PF00152.20 KEY70364.1 - 2.8e-68 230.3 0.0 3.5e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) 2OG-FeII_Oxy_3 PF13640.6 KEY70366.1 - 0.024 15.5 0.0 0.041 14.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Trehalase PF01204.18 KEY70367.1 - 6.5e-110 368.4 0.4 3e-109 366.2 0.4 1.8 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KEY70367.1 - 7.1e-06 25.2 0.4 0.00099 18.1 0.1 2.2 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Glyco_hydro_43 PF04616.14 KEY70368.1 - 9.1e-53 179.4 5.1 1.1e-52 179.1 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY70368.1 - 7.9e-25 87.8 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF3829 PF12889.7 KEY70369.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DHO_dh PF01180.21 KEY70371.1 - 2.2e-22 79.6 0.0 2.9e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase MFS_1 PF07690.16 KEY70372.1 - 1.7e-08 33.8 16.3 1.7e-08 33.8 16.3 4.1 3 2 1 4 4 4 3 Major Facilitator Superfamily PHO4 PF01384.20 KEY70373.1 - 1.8e-111 372.5 21.7 2e-111 372.3 21.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Fungal_trans PF04082.18 KEY70374.1 - 8.5e-27 93.8 0.0 1.4e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70374.1 - 6.1e-06 26.2 15.4 1.1e-05 25.4 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 KEY70376.1 - 4.7e-21 75.5 0.0 6.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY70376.1 - 3.5e-09 36.6 0.6 6.1e-05 22.7 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family YbaJ PF10757.9 KEY70376.1 - 0.059 13.9 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ Epimerase PF01370.21 KEY70378.1 - 3.6e-18 65.9 0.0 5.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY70378.1 - 1.1e-15 57.4 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY70378.1 - 5.2e-12 45.8 0.1 8.7e-12 45.1 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEY70378.1 - 7.5e-11 41.7 0.3 0.00016 20.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 KEY70378.1 - 8.8e-09 35.5 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY70378.1 - 3.7e-08 33.5 0.1 7.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEY70378.1 - 2.7e-07 30.3 0.0 7.1e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KEY70378.1 - 1e-05 24.9 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KEY70378.1 - 0.00072 19.2 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KEY70378.1 - 0.0021 17.6 0.1 0.0043 16.7 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KEY70378.1 - 0.0034 16.5 0.1 0.0095 15.1 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KEY70378.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY70378.1 - 0.061 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KEY70379.1 - 4.5e-19 68.7 0.0 6.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KEY70379.1 - 9.7e-17 60.8 0.0 2.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KEY70379.1 - 6e-09 37.1 0.0 1.2e-08 36.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GMC_oxred_N PF00732.19 KEY70380.1 - 7.9e-52 176.5 0.0 1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY70380.1 - 1.8e-30 106.4 0.0 3.1e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KEY70380.1 - 8.7e-05 21.9 0.2 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY70380.1 - 0.00088 19.5 0.0 0.0027 17.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY70380.1 - 0.00091 18.4 0.0 0.0031 16.6 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEY70380.1 - 0.0012 18.5 1.9 0.0072 15.9 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY70380.1 - 0.006 15.9 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY70380.1 - 0.0063 15.6 0.1 0.43 9.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEY70380.1 - 0.026 13.2 0.2 1.9 7.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF5097 PF17020.5 KEY70380.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) p450 PF00067.22 KEY70381.1 - 5.9e-65 219.8 0.0 6.9e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEY70382.1 - 4e-35 121.4 36.1 6.6e-35 120.7 36.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70382.1 - 8.5e-10 38.1 13.1 3.3e-09 36.1 13.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Tri3 PF07428.11 KEY70382.1 - 0.00014 20.9 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 OATP PF03137.20 KEY70382.1 - 0.00021 19.7 3.1 0.00044 18.7 3.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF2070 PF09843.9 KEY70382.1 - 3.8 5.7 6.9 7 4.8 6.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FAD_binding_3 PF01494.19 KEY70383.1 - 7.3e-10 38.6 0.3 0.00041 19.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain GFO_IDH_MocA PF01408.22 KEY70384.1 - 1.6e-15 58.0 0.0 3.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEY70384.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain ketoacyl-synt PF00109.26 KEY70385.1 - 2.1e-72 243.7 0.0 5.1e-72 242.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY70385.1 - 7.9e-32 109.8 0.0 1.8e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEY70385.1 - 9.5e-29 100.9 0.4 3.8e-26 92.3 0.9 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.6 KEY70385.1 - 3.7e-26 92.0 1.1 7.1e-26 91.1 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 KEY70385.1 - 2.4e-10 40.6 7.2 4.3e-09 36.5 0.7 3.4 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KEY70385.1 - 1.7e-09 37.8 2.3 0.00022 21.5 0.8 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KEY70385.1 - 2e-07 31.4 0.0 7.8e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY70385.1 - 3e-06 26.8 0.1 6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KEY70385.1 - 4.9 7.1 6.9 0.97 9.3 0.2 3.1 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Condensation PF00668.20 KEY70386.1 - 0.031 12.9 0.0 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Condensation domain FAD_binding_4 PF01565.23 KEY70387.1 - 1.4e-24 86.4 0.1 3.7e-24 85.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Transferase PF02458.15 KEY70387.1 - 3.3e-16 59.0 0.0 5.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Transferase family BBE PF08031.12 KEY70387.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 KEY70388.1 - 9.8e-73 244.8 2.0 2.3e-72 243.6 0.3 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KEY70388.1 - 6.3e-29 99.7 0.0 1.8e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KEY70388.1 - 3.2e-28 98.1 0.0 6.4e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEY70388.1 - 1.4e-26 93.8 0.0 2.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KEY70388.1 - 2.2e-24 86.0 0.0 4.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KEY70388.1 - 2.9e-13 50.4 0.0 7e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEY70388.1 - 3.3e-12 46.6 0.9 8.2e-12 45.3 0.9 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KEY70388.1 - 9e-10 38.7 1.8 1.4e-08 34.8 0.6 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 KEY70388.1 - 7.6e-09 36.2 0.0 2.1e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY70388.1 - 1.2e-07 32.3 0.0 3.2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEY70388.1 - 1.5e-07 31.1 1.9 5e-07 29.4 0.1 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain Epimerase PF01370.21 KEY70388.1 - 9.3e-06 25.3 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KEY70388.1 - 5.5e-05 23.1 0.0 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY70388.1 - 0.00018 20.9 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KAsynt_C_assoc PF16197.5 KEY70388.1 - 0.00022 21.7 0.0 0.00064 20.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 KEY70388.1 - 0.00037 20.5 0.6 0.0009 19.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_31 PF13847.6 KEY70388.1 - 0.00041 20.2 0.0 0.00098 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KEY70388.1 - 0.061 12.5 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KEY70388.1 - 0.2 11.6 0.6 0.91 9.4 0.6 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans PF04082.18 KEY70389.1 - 8.3e-18 64.4 1.0 1.5e-17 63.5 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70389.1 - 3.4e-06 27.1 12.4 3.4e-06 27.1 12.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2985 PF11204.8 KEY70389.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) FlxA PF14282.6 KEY70389.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.2 3 0 0 3 3 3 0 FlxA-like protein DUF974 PF06159.13 KEY70390.1 - 4.8e-83 278.7 0.0 5.7e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.29 KEY70391.1 - 1.3e-09 37.7 0.0 4.3e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 KEY70391.1 - 0.14 12.3 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Trp repressor protein ALS_ss_C PF10369.9 KEY70392.1 - 2.1e-14 53.5 0.0 1.7e-13 50.5 0.0 2.3 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KEY70392.1 - 1.9e-13 49.9 0.1 3.7e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KEY70392.1 - 9.9e-08 31.7 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KEY70392.1 - 0.032 14.2 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain OTCace_N PF02729.21 KEY70393.1 - 4.5e-44 150.1 0.1 6.4e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KEY70393.1 - 1.1e-43 149.0 0.0 1.8e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.8 KEY70394.1 - 1.8e-08 34.7 1.2 1.8e-07 31.5 1.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KEY70394.1 - 0.0015 19.0 0.2 2.6 8.6 0.0 4.0 4 0 0 4 4 4 2 Late embryogenesis abundant protein SART-1 PF03343.13 KEY70395.1 - 3.3e-186 620.6 60.3 3.9e-186 620.4 60.3 1.0 1 0 0 1 1 1 1 SART-1 family SNAP PF14938.6 KEY70396.1 - 1.1e-114 382.6 18.4 1.3e-114 382.4 18.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KEY70396.1 - 1.8e-07 31.3 14.9 0.00013 22.2 0.2 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY70396.1 - 0.0003 20.8 9.6 0.58 10.5 0.5 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70396.1 - 0.0047 16.9 21.6 0.092 12.9 0.3 7.1 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70396.1 - 0.006 16.5 7.6 18 5.6 0.1 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY70396.1 - 0.059 14.2 12.1 25 6.0 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70396.1 - 0.13 12.2 13.3 0.21 11.5 0.3 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY70396.1 - 0.13 13.0 16.4 24 5.8 0.0 6.3 6 1 2 8 8 8 0 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KEY70396.1 - 0.14 12.0 5.4 0.15 11.9 3.3 2.1 2 1 1 3 3 3 0 Phage-related minor tail protein AAA_assoc_2 PF16193.5 KEY70396.1 - 0.24 11.8 3.9 2.6 8.5 0.8 3.4 2 2 0 2 2 2 0 AAA C-terminal domain TPR_3 PF07720.12 KEY70396.1 - 0.56 10.3 6.8 3.1 7.9 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 KEY70397.1 - 1.4e-10 41.2 0.1 3.2e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PPI_Ypi1 PF07491.11 KEY70398.1 - 1e-23 82.9 0.4 2.3e-23 81.8 0.4 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor MFMR_assoc PF16596.5 KEY70398.1 - 2.3 8.7 11.6 0.34 11.4 4.3 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR MMR_HSR1 PF01926.23 KEY70399.1 - 6.6e-05 23.0 0.0 0.52 10.4 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.16 KEY70400.1 - 4.8e-16 58.4 0.2 8.7e-16 57.6 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.25 KEY70401.1 - 6.3e-75 252.5 0.0 9.8e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3712 PF12505.8 KEY70402.1 - 3.2e-07 30.6 0.0 1.7e-06 28.3 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) ADH_N PF08240.12 KEY70403.1 - 1.4e-33 115.0 1.9 3.6e-33 113.7 1.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY70403.1 - 8.4e-16 58.1 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY70403.1 - 2e-10 40.5 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY70403.1 - 1.1e-09 39.4 0.0 2.6e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KEY70403.1 - 0.0018 17.6 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KEY70403.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Staph_opine_DH PF10100.9 KEY70403.1 - 0.059 12.0 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase NAD_binding_8 PF13450.6 KEY70403.1 - 0.088 13.1 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain S10_plectin PF03501.15 KEY70404.1 - 5.9e-39 132.0 0.1 7.3e-39 131.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 KEY70405.1 - 1e-67 227.1 0.5 1.7e-67 226.3 0.5 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain COX6B PF02297.17 KEY70406.1 - 8.8e-18 64.3 2.9 1.1e-17 64.0 2.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KEY70406.1 - 0.011 15.7 1.4 0.021 14.8 1.4 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KEY70406.1 - 0.028 14.4 0.2 0.041 13.8 0.2 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 KEY70407.1 - 0.0022 17.7 0.1 0.0033 17.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KEY70408.1 - 2e-17 62.8 0.0 2.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY70408.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KEY70408.1 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEY70408.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Sec16_C PF12931.7 KEY70409.1 - 5.6e-13 49.2 0.1 5e-12 46.1 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KEY70409.1 - 2e-10 40.6 0.0 2e-10 40.6 0.0 2.9 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KEY70409.1 - 1.3e-07 32.2 2.4 0.16 12.9 0.1 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat Sec16 PF12932.7 KEY70409.1 - 0.0043 17.6 0.4 0.017 15.7 0.4 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PALB2_WD40 PF16756.5 KEY70409.1 - 0.081 11.8 0.1 1 8.2 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Prp18 PF02840.15 KEY70409.1 - 0.13 12.3 2.7 0.17 11.9 0.3 2.3 2 1 1 3 3 3 0 Prp18 domain GET2 PF08690.10 KEY70411.1 - 2.1e-51 175.5 0.0 2.5e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 stn_TNFRSF12A PF12191.8 KEY70411.1 - 0.17 12.1 1.8 0.23 11.7 0.0 2.1 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM135_C_rich PF15982.5 KEY70412.1 - 0.11 13.0 1.5 0.23 12.1 0.4 2.1 2 1 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF5134 PF17197.4 KEY70412.1 - 0.41 10.5 5.0 2.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) HLH PF00010.26 KEY70413.1 - 0.00045 20.1 0.0 0.00045 20.1 0.0 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Apt1 PF10351.9 KEY70413.1 - 0.96 8.2 7.2 1.8 7.3 7.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain TIP49 PF06068.13 KEY70414.1 - 5.1e-155 516.0 1.4 6.5e-155 515.6 1.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KEY70414.1 - 2.1e-20 72.6 0.2 6.8e-20 71.0 0.1 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KEY70414.1 - 1.6e-08 34.4 0.7 7e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KEY70414.1 - 3.4e-08 34.0 1.1 4.3e-05 24.0 0.1 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KEY70414.1 - 7.5e-07 28.7 1.0 1.4e-06 27.8 1.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KEY70414.1 - 7.2e-06 26.5 0.1 2.1e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KEY70414.1 - 0.0009 18.7 0.8 0.021 14.2 0.3 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KEY70414.1 - 0.0098 16.2 0.0 0.71 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEY70414.1 - 0.011 16.1 1.3 0.49 10.7 1.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY70414.1 - 0.011 15.7 0.5 3.5 7.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KEY70414.1 - 0.013 15.2 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEY70414.1 - 0.033 13.8 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEY70414.1 - 0.045 13.5 1.1 0.31 10.8 1.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY70414.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KEY70414.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fib_alpha PF08702.10 KEY70416.1 - 0.16 12.1 22.5 0.088 13.0 5.3 4.6 2 2 3 5 5 5 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 KEY70416.1 - 0.52 8.4 36.7 0.11 10.7 9.7 2.7 1 1 2 3 3 3 0 HOOK protein CREPT PF16566.5 KEY70416.1 - 0.72 10.0 23.0 0.052 13.7 4.4 4.6 1 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour GAT PF03127.14 KEY70416.1 - 1.2 9.5 5.7 4.5 7.6 1.2 3.1 2 0 0 2 2 2 0 GAT domain Atg14 PF10186.9 KEY70416.1 - 1.9 7.5 27.8 0.046 12.8 11.7 3.3 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 KEY70416.1 - 2.4 8.2 21.6 2.7 8.0 0.1 5.2 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus TssO PF17561.2 KEY70416.1 - 2.5 8.2 6.3 4.5 7.4 3.2 2.9 3 1 1 4 4 4 0 Type VI secretion system, TssO PspB PF06667.12 KEY70416.1 - 2.7 8.1 7.3 0.71 10.0 0.3 3.7 3 0 0 3 3 3 0 Phage shock protein B betaPIX_CC PF16523.5 KEY70416.1 - 3.1 7.7 9.9 7.3 6.5 0.2 3.4 3 0 0 3 3 3 0 betaPIX coiled coil COG2 PF06148.11 KEY70416.1 - 3.5 7.7 19.2 2.4 8.2 3.8 4.7 3 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KEY70416.1 - 4.6 7.6 10.2 2.5 8.4 2.3 3.9 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 KEY70416.1 - 9.1 6.4 48.1 1.5 9.0 25.9 4.8 1 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4746 PF15928.5 KEY70417.1 - 0.09 12.2 0.0 0.09 12.2 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4746) Gp_dh_C PF02800.20 KEY70418.1 - 7.8e-73 243.3 0.0 1.1e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEY70418.1 - 6.8e-38 129.1 0.1 1.5e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KEY70418.1 - 0.0044 17.1 0.5 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KEY70418.1 - 0.057 12.8 0.1 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GYF PF02213.16 KEY70419.1 - 7.1e-11 41.6 2.1 1.6e-10 40.4 2.1 1.6 1 0 0 1 1 1 1 GYF domain DTHCT PF08070.11 KEY70419.1 - 0.00071 20.3 4.7 0.00071 20.3 4.7 3.9 5 0 0 5 5 5 1 DTHCT (NUC029) region Gluconate_2-dh3 PF13618.6 KEY70419.1 - 0.29 11.4 2.9 1.8 8.8 2.9 2.2 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 EFTUD2 PF16004.5 KEY70419.1 - 2.8 8.6 20.3 0.52 10.9 0.3 3.9 3 1 1 4 4 4 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus UFD1 PF03152.14 KEY70420.1 - 6.3e-67 224.4 0.0 7.9e-67 224.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PP1_bind PF15276.6 KEY70421.1 - 0.13 12.6 2.3 0.19 12.0 1.6 1.6 1 1 0 1 1 1 0 Protein phosphatase 1 binding HTH_12 PF08461.10 KEY70423.1 - 0.0023 17.8 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain Med3 PF11593.8 KEY70426.1 - 0.011 15.0 4.1 0.011 15.0 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HJURP_C PF12347.8 KEY70427.1 - 0.13 12.4 0.2 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Paramyxo_ncap PF00973.19 KEY70428.1 - 0.27 10.1 2.5 0.32 9.9 2.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.12 KEY70428.1 - 1.3 8.8 11.6 1.6 8.5 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 rRNA_processing PF08524.11 KEY70428.1 - 1.9 8.5 12.9 1.7 8.7 9.9 1.9 1 1 1 2 2 2 0 rRNA processing EcsC PF12787.7 KEY70429.1 - 0.1 12.2 1.0 2.5 7.7 0.1 2.2 2 0 0 2 2 2 0 EcsC protein family E2F_CC-MB PF16421.5 KEY70429.1 - 0.11 12.9 3.9 0.11 12.9 1.0 2.3 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Exonuc_VII_L PF02601.15 KEY70429.1 - 0.27 10.7 3.2 0.44 10.1 3.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 KEY70429.1 - 1.2 9.8 4.5 3.5 8.3 4.5 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Cpn60_TCP1 PF00118.24 KEY70431.1 - 2.1e-87 293.8 10.8 7.9e-87 291.9 10.8 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 KEY70431.1 - 7.8e-38 129.0 0.4 1.6e-37 128.0 0.4 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.7 KEY70432.1 - 1.5e-40 139.0 1.1 2.3e-40 138.3 1.1 1.3 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KEY70432.1 - 2e-17 62.5 0.2 2.9e-17 62.0 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KEY70432.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Methyltr_RsmB-F PF01189.17 KEY70433.1 - 3.2e-76 255.5 0.0 4.8e-76 254.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KEY70433.1 - 2e-08 34.6 0.0 5.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KEY70433.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2431 PF10354.9 KEY70433.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.6 KEY70433.1 - 0.032 14.9 0.0 0.079 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KEY70433.1 - 0.056 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KEY70433.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KEY70433.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) XRCC4 PF06632.12 KEY70435.1 - 1.5e-05 24.0 12.0 5.9e-05 22.1 12.0 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PKcGMP_CC PF16808.5 KEY70435.1 - 0.0044 16.8 0.1 0.0044 16.8 0.1 2.9 3 1 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 KEY70435.1 - 0.095 12.8 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NOA36 PF06524.12 KEY70435.1 - 9 5.5 9.6 15 4.8 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.21 KEY70436.1 - 5e-42 144.1 0.0 2.9e-35 121.9 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family SL4P PF17618.2 KEY70436.1 - 0.078 13.0 0.3 16 5.6 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein UPF0061 PF02696.14 KEY70437.1 - 1.3e-126 423.1 0.0 1.7e-126 422.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.22 KEY70438.1 - 5.7e-74 249.6 0.0 4.1e-72 243.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KEY70438.1 - 2.9e-20 72.1 0.3 6.8e-20 70.9 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KEY70438.1 - 9.2e-20 71.1 0.0 2.8e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KEY70438.1 - 5.2e-17 61.1 0.2 5.2e-17 61.1 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KEY70438.1 - 2.2e-08 33.9 0.6 2.2e-08 33.9 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KEY70438.1 - 0.017 14.9 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CNTF PF01110.17 KEY70439.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor ACBP PF00887.19 KEY70440.1 - 4e-23 81.4 0.0 8.8e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein MRPL52 PF18699.1 KEY70440.1 - 0.056 13.6 2.5 11 6.3 0.1 3.6 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Ribonuclease_3 PF00636.26 KEY70441.1 - 2.7e-17 63.3 0.2 9.7e-17 61.5 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEY70441.1 - 9.6e-10 38.7 0.0 9.3e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KEY70441.1 - 1.5e-06 28.8 0.0 4.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif LPP20 PF02169.16 KEY70441.1 - 3 8.3 7.9 0.58 10.6 0.4 3.2 4 1 0 4 4 4 0 LPP20 lipoprotein MRP-S33 PF08293.11 KEY70442.1 - 1.6e-30 105.1 0.0 1.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GvpG PF05120.12 KEY70442.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Gas vesicle protein G PUF PF00806.19 KEY70444.1 - 5.1e-31 104.6 4.0 6.5e-06 25.5 0.0 8.4 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat PP2C PF00481.21 KEY70445.1 - 2.3e-42 145.4 0.0 3.6e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KEY70445.1 - 0.0025 17.5 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEY70445.1 - 0.0035 17.3 0.2 0.19 11.6 0.0 2.7 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) DUF5572 PF17733.1 KEY70446.1 - 5.6e-18 64.5 1.3 1.5e-17 63.2 1.3 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Glyco_hydro_47 PF01532.20 KEY70447.1 - 9.9e-164 545.6 0.0 1.1e-163 545.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KEY70447.1 - 0.0026 16.3 0.0 0.96 7.9 0.0 2.3 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 CactinC_cactus PF09732.9 KEY70447.1 - 0.03 14.3 0.0 0.23 11.4 0.0 2.3 3 0 0 3 3 3 0 Cactus-binding C-terminus of cactin protein Glycos_transf_1 PF00534.20 KEY70448.1 - 3.6e-33 114.5 0.0 5.3e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEY70448.1 - 1.2e-14 54.6 1.4 2.4e-14 53.7 1.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEY70448.1 - 1.2e-12 48.5 0.0 6.5e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEY70448.1 - 7.3e-07 29.8 9.0 7.3e-07 29.8 9.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 KEY70448.1 - 0.0042 17.2 0.0 1.2 9.2 0.0 2.6 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 KEY70448.1 - 0.0062 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 KEY70449.1 - 1.8e-49 168.5 0.2 1.3e-33 116.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70449.1 - 2.6e-21 76.1 0.8 1.2e-19 70.6 0.3 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY70449.1 - 0.00011 21.6 0.0 0.00027 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KEY70449.1 - 0.016 15.2 0.9 0.036 14.0 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Chorismate_synt PF01264.21 KEY70451.1 - 2.1e-119 398.1 0.0 1.2e-97 326.5 0.0 2.0 1 1 1 2 2 2 2 Chorismate synthase BPL_LplA_LipB PF03099.19 KEY70452.1 - 4.1e-06 26.7 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Fungal_trans_2 PF11951.8 KEY70454.1 - 3.8e-57 193.9 0.0 4.9e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70454.1 - 0.00017 21.6 8.5 0.00032 20.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KEY70457.1 - 3.1e-34 118.7 0.2 4e-34 118.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY70457.1 - 0.0007 18.6 0.2 0.0028 16.6 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY70457.1 - 0.0012 18.3 0.2 0.0025 17.3 0.2 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KEY70457.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 KEY70457.1 - 0.014 15.5 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain BC10 PF06726.12 KEY70459.1 - 2.1e-18 66.3 11.0 3.6e-18 65.6 11.0 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF5090 PF17009.5 KEY70459.1 - 0.18 11.7 1.7 0.25 11.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) YtfJ_HI0045 PF09695.10 KEY70460.1 - 1.5 8.5 5.0 11 5.6 0.1 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (YtfJ_HI0045) PAP2_3 PF14378.6 KEY70461.1 - 3.2e-36 124.8 17.2 3.2e-36 124.8 17.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KEY70461.1 - 0.00054 20.4 0.1 0.00054 20.4 0.1 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal ADH_zinc_N PF00107.26 KEY70462.1 - 2.3e-21 76.1 0.0 4.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY70462.1 - 2.7e-21 77.0 0.0 5.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase R3H PF01424.22 KEY70462.1 - 2.6e-10 40.1 0.0 4.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain ADH_N PF08240.12 KEY70462.1 - 1.4e-06 28.1 0.1 2.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RRM_1 PF00076.22 KEY70462.1 - 3e-05 23.7 0.1 6.7e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N_2 PF16884.5 KEY70462.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase HTH_51 PF18558.1 KEY70463.1 - 0.00045 20.0 0.1 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 KEY70463.1 - 0.019 15.7 0.0 0.063 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3632 PF12311.8 KEY70464.1 - 4e-28 99.0 0.1 5.2e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mito_fiss_reg PF05308.11 KEY70465.1 - 3 7.8 7.2 4.3 7.4 7.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_16 PF10294.9 KEY70467.1 - 3.2e-22 79.1 0.0 5.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KEY70467.1 - 0.00037 20.4 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Fer4_13 PF13370.6 KEY70469.1 - 0.59 10.7 5.8 47 4.6 0.1 4.3 4 1 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I RNA_pol_N PF01194.17 KEY70470.1 - 5.2e-29 100.3 1.2 7.1e-29 99.9 1.2 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KEY70470.1 - 0.066 13.5 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DIOX_N PF14226.6 KEY70471.1 - 1.3e-31 109.8 0.0 1.5e-30 106.3 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY70471.1 - 2.8e-13 50.2 0.0 9e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KEY70471.1 - 4.3e-09 36.9 10.0 0.0036 18.1 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY70471.1 - 0.011 16.0 0.5 23 5.4 0.0 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain 4F5 PF04419.14 KEY70472.1 - 4.7e-08 33.8 12.0 5.6e-08 33.5 12.0 1.1 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 KEY70472.1 - 0.0023 18.0 1.6 0.0055 16.8 0.9 1.9 2 0 0 2 2 2 1 Zinc-binding Phage_Capsid_P3 PF09018.11 KEY70472.1 - 0.13 11.1 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 P3 major capsid protein DUF1479 PF07350.12 KEY70474.1 - 4.1e-145 483.7 0.0 4.8e-145 483.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Bap31 PF05529.12 KEY70475.1 - 1.4e-48 164.2 10.0 2e-48 163.6 10.0 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KEY70475.1 - 5.1e-13 48.8 10.4 5.1e-13 48.8 10.4 1.6 2 0 0 2 2 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Mod_r PF07200.13 KEY70475.1 - 0.0027 17.8 1.5 0.0048 17.0 1.5 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CEP63 PF17045.5 KEY70475.1 - 0.0036 17.3 1.9 0.0053 16.7 1.9 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa V_ATPase_I PF01496.19 KEY70475.1 - 0.006 14.6 1.2 0.0093 13.9 1.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DHR10 PF18595.1 KEY70475.1 - 0.011 15.8 4.1 0.019 15.0 4.1 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KEY70475.1 - 0.016 15.6 0.3 0.034 14.5 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KEY70475.1 - 0.021 13.7 3.8 0.029 13.3 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC-167 PF15188.6 KEY70475.1 - 0.024 15.0 2.4 0.061 13.7 2.4 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 KEY70475.1 - 0.033 14.3 0.4 0.033 14.3 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KEY70475.1 - 0.072 12.9 7.0 0.067 13.0 1.8 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF192 PF02643.15 KEY70475.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 MscS_TM PF12794.7 KEY70475.1 - 0.22 10.3 5.2 0.2 10.5 0.2 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Csm1_N PF18504.1 KEY70475.1 - 0.42 11.0 6.6 0.32 11.3 4.1 1.9 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2730 PF10805.8 KEY70475.1 - 1.1 9.4 5.0 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) EZH2_N PF18601.1 KEY70476.1 - 2.9e-37 126.8 3.8 8.1e-37 125.4 3.8 1.8 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KEY70476.1 - 7.9e-24 83.0 1.1 1.7e-23 82.0 1.1 1.6 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KEY70476.1 - 3.6e-17 63.3 1.1 1.3e-16 61.5 0.1 2.6 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KEY70476.1 - 1.2e-06 28.9 12.9 1.2e-06 28.9 12.9 3.7 2 1 1 3 3 3 2 CXC domain Pil1 PF13805.6 KEY70477.1 - 7e-126 419.1 0.1 8.8e-126 418.8 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KEY70477.1 - 0.34 11.4 7.0 4.7 7.7 0.0 3.2 3 1 1 4 4 4 0 Apg6 coiled-coil region LSM PF01423.22 KEY70478.1 - 1e-10 41.2 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEY70478.1 - 0.0003 20.9 0.1 0.0014 18.7 0.1 2.1 1 1 0 1 1 1 1 Ataxin 2 SM domain XPG_N PF00752.17 KEY70479.1 - 6.1e-32 110.1 0.0 1.4e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KEY70479.1 - 7e-28 96.8 0.0 1.9e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KEY70479.1 - 0.0078 16.1 0.6 0.0078 16.1 0.6 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif XPG_I_2 PF12813.7 KEY70479.1 - 0.011 15.3 0.1 0.027 14.0 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing DUF1943 PF09172.11 KEY70479.1 - 0.017 14.3 0.2 0.053 12.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) 5_3_exonuc PF01367.20 KEY70479.1 - 0.065 13.8 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold F-box-like PF12937.7 KEY70480.1 - 3.9e-08 33.0 1.3 7.2e-08 32.2 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY70480.1 - 2.1e-06 27.4 1.2 4.3e-06 26.5 1.2 1.6 1 0 0 1 1 1 1 F-box domain HET PF06985.11 KEY70481.1 - 2.2e-25 89.7 0.0 4.1e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP70 PF00012.20 KEY70482.1 - 2.9e-224 745.7 5.5 3.3e-224 745.6 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY70482.1 - 4.1e-16 58.7 0.4 2.6e-15 56.1 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KEY70482.1 - 0.00066 19.5 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KEY70482.1 - 0.041 13.4 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KEY70482.1 - 0.27 11.7 2.7 16 6.0 0.0 3.1 3 2 0 3 3 3 0 Cell division protein FtsA ATPgrasp_N PF18130.1 KEY70485.1 - 6.7e-18 65.0 0.2 1.7e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KEY70485.1 - 3.1e-11 43.1 0.0 5.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEY70485.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KEY70485.1 - 0.0047 16.4 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 KEY70485.1 - 0.038 13.7 0.1 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Methyltransf_31 PF13847.6 KEY70486.1 - 2.5e-18 66.3 0.0 4.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY70486.1 - 1.5e-13 51.2 0.0 3.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY70486.1 - 4.6e-11 43.3 0.0 1.2e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY70486.1 - 2.5e-10 40.9 0.0 5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY70486.1 - 2.5e-07 30.7 0.0 5.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY70486.1 - 1.6e-05 24.6 0.0 4.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEY70486.1 - 4.6e-05 22.9 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEY70486.1 - 0.0005 19.4 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KEY70486.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FAD_binding_8 PF08022.12 KEY70486.1 - 0.0014 18.7 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain Methyltransf_32 PF13679.6 KEY70486.1 - 0.0027 17.7 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEY70486.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KEY70486.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ferric_reduct PF01794.19 KEY70486.1 - 0.031 14.4 7.4 0.076 13.1 7.4 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component TPMT PF05724.11 KEY70486.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) PTR2 PF00854.21 KEY70487.1 - 1e-35 123.3 2.7 4.7e-35 121.2 2.7 1.8 1 1 0 1 1 1 1 POT family MFS_1_like PF12832.7 KEY70487.1 - 0.029 13.2 0.0 0.029 13.2 0.0 2.1 2 1 0 2 2 2 0 MFS_1 like family DUF4381 PF14316.6 KEY70487.1 - 0.32 11.2 3.1 1.7 8.9 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Methyltransf_11 PF08241.12 KEY70488.1 - 4.9e-20 72.0 0.0 7.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY70488.1 - 4.7e-17 62.5 0.0 7.4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY70488.1 - 3e-14 53.2 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY70488.1 - 3.7e-14 53.3 0.0 6.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY70488.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY70488.1 - 3.3e-08 33.2 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KEY70488.1 - 8e-07 28.4 0.0 1.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 KEY70488.1 - 1.4e-05 25.0 0.0 4.9e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 KEY70488.1 - 0.0005 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 KEY70488.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.16 KEY70488.1 - 0.077 11.5 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_2 PF12796.7 KEY70489.1 - 1.6e-67 224.1 0.0 2e-17 63.5 0.0 6.8 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY70489.1 - 6.2e-51 164.4 2.1 0.00016 21.8 0.0 11.3 11 0 0 11 11 10 8 Ankyrin repeat Ank PF00023.30 KEY70489.1 - 2.9e-50 166.6 0.8 0.0002 21.6 0.0 10.6 9 1 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 KEY70489.1 - 1.6e-48 162.5 4.2 1e-09 38.7 0.0 7.7 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY70489.1 - 2.3e-32 110.6 3.6 1.4e-07 31.6 0.0 6.5 2 2 4 7 7 7 7 Ankyrin repeats (many copies) NACHT PF05729.12 KEY70489.1 - 4.1e-06 26.8 0.1 1.1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY70489.1 - 3.8e-05 24.1 0.7 0.00031 21.2 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY70489.1 - 0.00036 20.8 0.0 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF4988 PF16378.5 KEY70489.1 - 0.0024 17.5 0.0 1.7 8.3 0.0 3.5 2 1 1 3 3 3 1 Domain of unknown function KAP_NTPase PF07693.14 KEY70489.1 - 0.0053 16.0 0.6 0.097 11.9 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 KEY70489.1 - 0.045 14.3 0.0 0.81 10.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter VWA_3_C PF18571.1 KEY70489.1 - 0.091 12.7 0.5 1.2e+02 2.7 0.0 3.8 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain RNA_helicase PF00910.22 KEY70489.1 - 0.17 12.3 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase CTP_transf_like PF01467.26 KEY70492.1 - 1.9e-05 24.9 0.1 7.6e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Mito_fiss_reg PF05308.11 KEY70493.1 - 0.28 11.3 1.6 0.28 11.2 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KEY70493.1 - 0.56 10.2 8.2 0.73 9.9 8.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rxt3 PF08642.10 KEY70494.1 - 2e-42 144.9 0.4 4.5e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KEY70494.1 - 3.5e-05 23.8 0.0 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 2 LCCL domain Zip PF02535.22 KEY70494.1 - 10 5.3 7.4 18 4.4 7.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1674 PF07896.12 KEY70495.1 - 6.9e-18 64.9 5.7 1.5e-17 63.8 5.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) PHO4 PF01384.20 KEY70497.1 - 3e-114 381.6 7.9 3.5e-114 381.4 7.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4748 PF15932.5 KEY70497.1 - 0.047 13.4 0.2 0.16 11.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Glyco_hydro_10 PF00331.20 KEY70498.1 - 6.2e-98 327.8 0.0 7.5e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KEY70498.1 - 8.7e-13 48.0 6.2 2.2e-12 46.7 6.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 KEY70498.1 - 0.23 9.5 5.1 0.34 8.9 5.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aminotran_5 PF00266.19 KEY70499.1 - 1.7e-16 60.1 0.0 1.5e-14 53.8 0.0 2.8 2 1 0 2 2 2 1 Aminotransferase class-V Pyrophosphatase PF00719.19 KEY70500.1 - 1e-42 145.7 0.0 1.3e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DCX PF03607.17 KEY70501.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Doublecortin PADR1 PF08063.12 KEY70503.1 - 0.0043 16.8 0.1 0.0043 16.8 0.1 1.5 2 0 0 2 2 2 1 PADR1 (NUC008) domain Abhydrolase_2 PF02230.16 KEY70506.1 - 5.1e-23 82.0 0.0 7.2e-21 75.0 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KEY70506.1 - 1.8e-05 24.3 0.0 3.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEY70506.1 - 0.0025 17.1 0.1 11 5.2 0.0 3.1 3 0 0 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 KEY70506.1 - 0.004 16.8 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KEY70506.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 KEY70506.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GST_C PF00043.25 KEY70508.1 - 7.2e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY70508.1 - 0.00022 21.3 0.0 0.0007 19.7 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY70508.1 - 0.0049 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0149 PF03695.13 KEY70508.1 - 0.089 13.1 0.1 0.25 11.6 0.1 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0149) Fungal_trans PF04082.18 KEY70509.1 - 6.6e-07 28.6 0.2 2.1e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70509.1 - 1.2e-06 28.5 8.4 2.8e-06 27.3 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KEY70510.1 - 4.1e-25 88.7 0.1 5.4e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY70510.1 - 1.7e-21 77.0 0.2 3.5e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEY70510.1 - 1.3e-07 31.3 0.2 1.1e-05 25.1 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY70510.1 - 4.2e-06 27.0 0.2 9e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KEY70510.1 - 0.0075 16.4 0.6 0.024 14.8 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KEY70510.1 - 0.035 14.2 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KEY70510.1 - 0.037 13.0 0.0 0.11 11.5 0.0 1.8 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEY70510.1 - 0.08 13.4 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CPV_Polyhedrin PF17515.2 KEY70511.1 - 0.042 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin JSRP PF15312.6 KEY70511.1 - 0.17 11.8 1.7 2.6 8.0 0.1 2.6 2 1 1 3 3 3 0 Junctional sarcoplasmic reticulum protein adh_short PF00106.25 KEY70512.1 - 0.0088 15.5 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70512.1 - 0.011 15.3 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Acetyltransf_8 PF13523.6 KEY70513.1 - 1.5e-40 138.3 0.0 2.5e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 KEY70514.1 - 5.9e-24 85.1 1.4 8.5e-24 84.6 0.5 1.7 2 0 0 2 2 2 1 Mitochondrial calcium uniporter MDD_C PF18376.1 KEY70516.1 - 1.5e-63 214.0 0.1 2e-63 213.6 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KEY70516.1 - 2.6e-08 34.0 0.9 2.6e-08 34.0 0.9 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF647 PF04884.14 KEY70517.1 - 7.9e-94 313.8 3.6 9.7e-94 313.5 3.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.17 KEY70518.1 - 1.7e-43 149.3 10.5 3.4e-41 141.8 10.5 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase CLN3 PF02487.17 KEY70520.1 - 1.1e-159 531.9 2.9 1.2e-159 531.6 2.9 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KEY70520.1 - 1.3e-06 27.6 22.2 2.8e-06 26.5 5.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KEY70521.1 - 4.2e-07 29.1 0.1 5.9e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70521.1 - 0.03 14.4 7.1 0.064 13.4 7.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4148 PF13663.6 KEY70522.1 - 0.17 12.1 2.3 0.29 11.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Peptidase_S28 PF05577.12 KEY70524.1 - 3.7e-51 174.3 0.1 1.3e-50 172.4 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Lactamase_B_2 PF12706.7 KEY70526.1 - 5.9e-07 29.2 1.8 8.3e-05 22.2 1.8 2.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEY70526.1 - 1.7e-05 25.0 0.1 2.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf_UBZ PF18439.1 KEY70527.1 - 0.026 14.1 1.3 4.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nucleotid_trans PF03407.16 KEY70528.1 - 3.5e-07 30.4 0.1 1.6e-06 28.3 0.0 1.8 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KEY70528.1 - 5.7e-07 29.5 1.9 1.2e-06 28.5 1.8 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KEY70528.1 - 0.00054 19.6 0.1 0.0011 18.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF273 PNK3P PF08645.11 KEY70530.1 - 6.3e-54 182.0 0.0 9.5e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KEY70530.1 - 7.6e-24 84.5 0.0 3.9e-21 75.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY70530.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY70530.1 - 0.033 13.6 0.1 3.3 7.1 0.0 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Rad17 PF03215.15 KEY70530.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KEY70530.1 - 0.075 12.8 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY70530.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KEY70530.1 - 0.18 12.4 0.1 1.1 9.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain Med18 PF09637.10 KEY70531.1 - 1.1e-20 74.6 0.0 1.3e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Egh16-like PF11327.8 KEY70532.1 - 2.8e-49 168.0 11.1 2.8e-49 168.0 11.1 2.6 2 1 1 3 3 3 1 Egh16-like virulence factor Izumo-Ig PF16706.5 KEY70532.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain DUF1264 PF06884.11 KEY70534.1 - 6.2e-78 260.3 0.0 7.2e-78 260.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF3292 PF11696.8 KEY70537.1 - 2e-267 888.9 0.0 2.3e-267 888.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Lactamase_B PF00753.27 KEY70537.1 - 0.0057 16.7 0.8 0.027 14.5 0.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pex14_N PF04695.13 KEY70537.1 - 0.038 14.6 0.0 8.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex24p PF06398.11 KEY70537.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LSM PF01423.22 KEY70539.1 - 4.4e-18 64.7 0.0 5e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glyco_tranf_2_2 PF10111.9 KEY70540.1 - 0.057 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Transglut_core3 PF13471.6 KEY70541.1 - 1.1 9.2 4.2 2.9 7.8 0.0 3.0 3 1 0 3 3 3 0 Transglutaminase-like superfamily WSC PF01822.19 KEY70542.1 - 3.1e-70 232.4 59.8 1.3e-15 57.4 6.1 5.4 5 0 0 5 5 5 5 WSC domain PQQ_3 PF13570.6 KEY70542.1 - 6.6e-05 23.3 11.0 0.021 15.3 0.6 4.3 3 1 0 3 3 3 2 PQQ-like domain ASH PF15780.5 KEY70542.1 - 0.0005 20.2 2.7 0.55 10.5 0.0 3.5 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ_2 PF13360.6 KEY70542.1 - 0.00092 18.9 0.4 0.096 12.3 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain Prok-RING_1 PF14446.6 KEY70542.1 - 0.047 13.6 1.0 0.16 11.9 1.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PQQ PF01011.21 KEY70542.1 - 0.28 11.2 9.5 3.6 7.7 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat Snf7 PF03357.21 KEY70544.1 - 8.3e-42 142.7 14.1 1e-41 142.4 14.1 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KEY70544.1 - 1.1e-05 25.8 4.0 0.013 15.9 1.4 2.9 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KEY70544.1 - 0.0053 17.1 13.4 0.053 13.9 0.0 3.8 3 1 1 4 4 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zwint PF15556.6 KEY70544.1 - 0.011 15.2 9.0 0.015 14.8 9.0 1.3 1 0 0 1 1 1 0 ZW10 interactor SlyX PF04102.12 KEY70544.1 - 0.016 15.8 10.5 0.056 14.1 0.2 3.5 1 1 2 3 3 3 0 SlyX FlaC_arch PF05377.11 KEY70544.1 - 0.055 13.9 8.6 9.8 6.7 0.0 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 KEY70544.1 - 0.055 13.7 11.3 0.21 11.9 11.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Muted PF14942.6 KEY70544.1 - 0.063 13.6 11.3 0.2 12.0 3.5 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FliD_C PF07195.12 KEY70544.1 - 0.077 12.4 0.0 0.077 12.4 0.0 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Allexi_40kDa PF05549.11 KEY70544.1 - 0.095 12.2 3.7 0.53 9.7 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein HsbA PF12296.8 KEY70544.1 - 0.098 13.1 2.9 2.1 8.8 2.9 2.4 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF2205 PF10224.9 KEY70544.1 - 0.11 12.5 10.0 0.23 11.5 5.8 3.1 1 1 2 3 3 3 0 Short coiled-coil protein Prefoldin_2 PF01920.20 KEY70544.1 - 0.12 12.3 15.7 0.14 12.1 0.0 4.1 2 1 3 5 5 5 0 Prefoldin subunit Endotoxin_N PF03945.14 KEY70544.1 - 0.22 11.2 3.5 0.56 9.9 0.1 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain TraF_2 PF13729.6 KEY70544.1 - 0.22 10.9 3.8 0.13 11.6 0.4 2.0 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein FapA PF03961.13 KEY70544.1 - 0.32 9.6 12.8 0.96 8.0 3.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 KEY70544.1 - 0.34 10.8 4.0 43 4.0 4.8 2.4 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.6 KEY70544.1 - 0.39 10.0 9.8 0.52 9.6 9.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 KEY70544.1 - 0.44 9.0 2.0 0.65 8.5 0.6 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family APG6_N PF17675.1 KEY70544.1 - 0.47 11.0 21.0 1.8 9.1 6.5 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Prominin PF05478.11 KEY70544.1 - 0.49 8.3 5.0 0.63 7.9 5.0 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 KEY70544.1 - 0.51 11.0 11.7 7.5 7.3 1.2 2.7 1 1 1 2 2 2 0 Initiation control protein YabA COG6 PF06419.11 KEY70544.1 - 0.52 8.5 9.2 0.32 9.2 3.8 2.1 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 Mod_r PF07200.13 KEY70544.1 - 0.76 9.9 14.0 0.25 11.5 8.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NYD-SP28_assoc PF14775.6 KEY70544.1 - 0.87 9.7 8.4 5.7 7.1 1.4 3.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF2120 PF09893.9 KEY70544.1 - 1.2 9.3 5.9 0.69 10.0 2.8 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DASH_Spc19 PF08287.11 KEY70544.1 - 1.5 8.7 9.9 6.7 6.6 9.5 2.1 1 1 1 2 2 2 0 Spc19 DUF3138 PF11336.8 KEY70544.1 - 1.9 7.0 3.7 2.9 6.4 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Swi5 PF07061.11 KEY70544.1 - 3.5 7.8 12.0 6.7e+02 0.5 0.4 3.2 1 1 1 2 2 2 0 Swi5 DUF4446 PF14584.6 KEY70544.1 - 4.1 7.4 9.8 5.5 7.0 1.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4094 PF13334.6 KEY70544.1 - 4.5 7.8 7.1 9.6 6.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) XhlA PF10779.9 KEY70544.1 - 7.1 6.9 12.9 3.4 8.0 0.1 3.9 2 1 1 3 3 3 0 Haemolysin XhlA WD40 PF00400.32 KEY70545.1 - 4.8e-24 84.2 4.8 0.0013 19.5 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 KEY70545.1 - 1.9e-14 53.3 0.6 4.9e-14 52.0 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY70545.1 - 6e-06 26.0 0.4 4.1e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KEY70545.1 - 0.00092 19.5 0.1 0.44 10.9 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain MgtE_N PF03448.17 KEY70545.1 - 0.0031 18.1 0.0 0.008 16.8 0.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain Nup160 PF11715.8 KEY70545.1 - 0.0063 15.2 0.0 2.9 6.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 SmpA_OmlA PF04355.13 KEY70545.1 - 0.0074 16.1 2.0 0.14 12.0 0.1 3.1 4 0 0 4 4 4 1 SmpA / OmlA family F-box_4 PF15966.5 KEY70545.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box BBS2_Mid PF14783.6 KEY70545.1 - 0.039 14.0 0.1 1.9 8.6 0.0 3.4 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 KEY70545.1 - 0.095 11.6 0.0 0.57 9.0 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PH_10 PF15411.6 KEY70546.1 - 3.8e-41 140.2 0.5 7.8e-41 139.2 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KEY70546.1 - 1.9e-33 114.6 0.0 3.7e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KEY70546.1 - 8.7e-25 88.0 0.0 1.4e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KEY70546.1 - 1.6e-08 34.4 0.0 4.3e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 PB1 domain MFS_1 PF07690.16 KEY70547.1 - 0.016 14.1 0.0 0.016 14.1 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily PepSY_TM PF03929.16 KEY70547.1 - 0.1 12.2 0.5 0.11 12.1 0.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Phage_holin_2_4 PF16082.5 KEY70547.1 - 1.2 8.9 5.2 2 8.2 5.2 1.5 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like E_Pc_C PF06752.12 KEY70548.1 - 0.045 13.8 0.3 0.058 13.5 0.3 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus OPT PF03169.15 KEY70549.1 - 4.1e-170 567.4 45.9 4.7e-170 567.2 45.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans_2 PF11951.8 KEY70550.1 - 0.0039 16.1 0.3 0.015 14.2 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rtt106 PF08512.12 KEY70551.1 - 1.4e-27 95.9 0.1 4.4e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KEY70551.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SDA1 PF05285.12 KEY70551.1 - 1.4 8.3 29.8 2.2 7.6 29.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEY70551.1 - 4.3 5.4 35.5 5.9 5.0 35.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEY70551.1 - 5.4 5.2 19.6 7.4 4.7 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KEY70551.1 - 8.3 5.6 29.9 15 4.8 29.9 1.3 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 KEY70552.1 - 5.8e-54 183.2 33.4 6.5e-54 183.0 33.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 KEY70552.1 - 0.32 9.9 9.2 0.31 10.0 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 KEY70552.1 - 0.38 9.8 12.4 0.51 9.4 12.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF5427 PF10310.9 KEY70552.1 - 0.81 8.6 18.6 1 8.3 18.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MCM_bind PF09739.9 KEY70552.1 - 1.1 7.7 12.0 1.1 7.6 12.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4228 PF14009.6 KEY70552.1 - 1.5 9.2 7.4 2.7 8.4 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Serinc PF03348.15 KEY70552.1 - 1.6 7.6 4.5 2 7.3 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) TP53IP5 PF15331.6 KEY70552.1 - 2.1 8.5 15.1 2.7 8.1 15.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SpoIIP PF07454.11 KEY70552.1 - 2.5 7.5 17.4 3.5 7.0 17.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 KEY70552.1 - 2.6 7.0 16.0 3 6.8 16.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 KEY70552.1 - 2.7 6.2 31.0 3.3 5.9 31.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KEY70552.1 - 3.1 5.8 13.5 3.6 5.6 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 KEY70552.1 - 3.6 5.9 6.6 4.5 5.6 6.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 KEY70552.1 - 4.6 6.2 5.4 5.4 6.0 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein Peptidase_M28 PF04389.17 KEY70553.1 - 1.7e-32 112.8 0.0 2.3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY70553.1 - 2.3e-13 49.9 0.1 4.4e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY70553.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-C2H2 PF00096.26 KEY70556.1 - 0.0052 17.2 0.8 0.0052 17.2 0.8 5.2 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY70556.1 - 0.016 15.6 0.5 0.016 15.6 0.5 4.5 8 0 0 8 8 8 0 Zinc-finger double domain zf-CHCC PF10276.9 KEY70556.1 - 0.023 14.8 4.6 0.89 9.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger domain Zn_ribbon_recom PF13408.6 KEY70556.1 - 3.5 8.2 6.0 1.9 9.1 0.9 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DSPc PF00782.20 KEY70557.1 - 3.3e-15 56.1 0.0 3.9e-08 33.2 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KEY70557.1 - 0.0035 17.6 0.0 0.0076 16.5 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KEY70557.1 - 0.0058 16.2 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4955 PF16315.5 KEY70557.1 - 0.019 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) Condensation PF00668.20 KEY70558.1 - 8.1e-63 212.7 0.0 1.1e-19 70.4 0.0 4.2 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 KEY70558.1 - 2.3e-25 89.1 0.0 4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEY70558.1 - 0.01 16.2 0.2 0.61 10.5 0.0 3.5 3 0 0 3 3 3 0 Phosphopantetheine attachment site SAPS PF04499.15 KEY70559.1 - 1.2e-165 552.0 6.1 7.8e-124 414.1 0.0 3.5 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein PRIMA1 PF16101.5 KEY70559.1 - 1.6 8.8 6.0 5.9 6.9 6.0 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Peptidase_S8 PF00082.22 KEY70560.1 - 2.1e-32 112.6 6.0 3e-32 112.1 5.4 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 KEY70560.1 - 2e-11 44.4 0.1 3.2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 GCFC PF07842.12 KEY70561.1 - 6.6e-67 226.0 1.3 1.2e-66 225.2 1.3 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KEY70561.1 - 1.8e-14 53.4 2.9 1.8e-14 53.4 2.9 2.3 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 KEY70561.1 - 8.2e-10 39.0 13.5 8.2e-10 39.0 13.5 3.4 2 2 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KEY70561.1 - 8.5e-08 32.2 2.2 8.5e-08 32.2 2.2 2.4 2 1 0 2 2 2 1 G-patch domain HEAT PF02985.22 KEY70562.1 - 0.00074 19.6 2.4 1.6 9.2 0.2 5.0 5 0 0 5 5 4 1 HEAT repeat CLASP_N PF12348.8 KEY70562.1 - 0.0019 17.8 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 KEY70562.1 - 0.0025 17.9 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY70562.1 - 0.0029 18.0 4.8 2.2 8.7 0.2 4.5 2 2 4 6 6 6 2 HEAT repeats DUF4763 PF15960.5 KEY70562.1 - 0.0061 15.9 0.5 0.013 14.8 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Syntaxin PF00804.25 KEY70562.1 - 0.0099 15.6 1.8 0.029 14.0 1.8 1.7 1 0 0 1 1 1 1 Syntaxin IFRD PF05004.13 KEY70562.1 - 0.015 14.4 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TAN PF11640.8 KEY70562.1 - 0.017 15.2 0.8 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair GHMP_kinases_C PF08544.13 KEY70562.1 - 0.039 14.3 1.3 6.2 7.3 0.0 3.1 2 1 0 2 2 2 0 GHMP kinases C terminal Jnk-SapK_ap_N PF09744.9 KEY70562.1 - 0.25 11.5 12.5 0.64 10.2 12.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 KEY70562.1 - 0.29 11.4 9.8 1.2 9.4 1.8 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 KEY70562.1 - 0.49 10.4 10.5 1.9 8.6 10.5 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 KEY70562.1 - 1.5 8.5 10.0 3 7.5 10.0 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Cep57_CLD_2 PF14197.6 KEY70562.1 - 2.2 8.4 17.1 6.1 7.0 6.7 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF812 PF05667.11 KEY70562.1 - 3.1 6.6 11.0 5.6 5.7 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KEY70562.1 - 3.3 8.3 14.4 1.2 9.7 10.8 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KEY70562.1 - 3.9 7.8 11.0 0.85 9.9 6.7 2.2 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.6 KEY70562.1 - 4.3 6.8 7.8 7.7 6.0 7.8 1.3 1 0 0 1 1 1 0 TMCO5 family YabA PF06156.13 KEY70562.1 - 5.2 7.8 6.4 23 5.7 6.5 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Fez1 PF06818.15 KEY70562.1 - 5.4 7.4 10.4 2.7 8.4 7.8 1.7 2 0 0 2 2 1 0 Fez1 WI12 PF07107.11 KEY70563.1 - 0.017 15.2 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Wound-induced protein WI12 DUF3429 PF11911.8 KEY70564.1 - 1e-44 152.3 7.2 1.3e-44 152.0 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) NARP1 PF12569.8 KEY70564.1 - 0.022 13.7 16.3 0.028 13.3 16.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ctr PF04145.15 KEY70564.1 - 0.45 11.1 3.5 1.8 9.2 3.5 2.0 1 1 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 KEY70564.1 - 0.63 8.7 17.5 0.9 8.2 17.5 1.2 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 KEY70564.1 - 2.7 6.9 23.8 3.9 6.4 23.8 1.2 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.16 KEY70564.1 - 3.8 7.5 5.0 6.5 6.7 5.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SHR-BD PF06650.12 KEY70565.1 - 9.3e-98 326.9 0.0 7.9e-95 317.3 0.0 2.9 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KEY70565.1 - 5.8e-95 317.2 17.1 1.7e-91 305.8 1.1 6.6 7 0 0 7 7 7 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KEY70565.1 - 1.3e-83 280.5 5.5 1.2e-81 274.0 0.0 4.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KEY70565.1 - 2.3e-76 255.5 7.5 2.2e-71 239.3 1.1 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KEY70565.1 - 2.9e-39 133.8 0.0 1e-38 132.0 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KEY70565.1 - 6.5e-07 29.6 0.2 4e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain HAD_SAK_1 PF10307.9 KEY70565.1 - 0.015 15.2 0.2 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TORC_M PF12885.7 KEY70565.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DUF896 PF05979.12 KEY70565.1 - 0.42 10.5 8.8 1.7 8.5 0.8 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Nucleos_tra2_C PF07662.13 KEY70567.1 - 4.7e-69 232.4 0.6 4.7e-69 232.4 0.6 2.5 2 1 0 2 2 2 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KEY70567.1 - 1.3e-23 83.4 2.4 1.3e-23 83.4 2.4 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus HRI1 PF16815.5 KEY70568.1 - 2.8e-71 239.9 3.9 3.2e-71 239.7 3.9 1.0 1 0 0 1 1 1 1 Protein HRI1 Aminotran_3 PF00202.21 KEY70569.1 - 2.2e-86 290.1 0.0 2.7e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Ceramidase PF05875.12 KEY70570.1 - 4.2e-77 259.1 1.1 5e-77 258.9 1.1 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 KEY70570.1 - 0.18 11.0 5.5 0.094 12.0 2.8 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PLA2_B PF01735.18 KEY70571.1 - 6.1e-17 61.2 0.1 7.3e-11 41.2 0.1 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain ACPS PF01648.20 KEY70571.1 - 0.0048 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ANXA2R PF15721.5 KEY70573.1 - 0.028 15.0 1.1 0.034 14.7 1.1 1.2 1 0 0 1 1 1 0 Annexin-2 receptor DUF2985 PF11204.8 KEY70575.1 - 3.2e-22 78.5 4.4 6.2e-22 77.6 4.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Binary_toxB PF03495.14 KEY70576.1 - 0.23 11.7 0.7 0.52 10.5 0.7 1.6 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain NmrA PF05368.13 KEY70577.1 - 5.8e-13 48.9 0.0 8.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KEY70577.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain E1_DerP2_DerF2 PF02221.15 KEY70578.1 - 0.9 10.0 12.1 0.54 10.7 3.1 2.7 1 1 1 2 2 2 0 ML domain Fungal_trans PF04082.18 KEY70579.1 - 4.3e-13 48.9 0.0 6.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70579.1 - 6.4e-11 42.2 9.4 1.1e-10 41.5 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KEY70580.1 - 1.9e-32 112.7 0.0 2.4e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY70580.1 - 8.5e-15 55.1 0.1 2.7e-11 43.8 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY70580.1 - 1.1e-06 28.0 0.0 3.4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KEY70580.1 - 9.7e-05 21.6 0.1 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KEY70580.1 - 0.0001 22.0 5.5 0.89 9.1 1.2 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY70580.1 - 0.00028 20.9 3.2 2.7 8.0 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEY70580.1 - 0.00056 19.3 0.0 0.005 16.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEY70580.1 - 0.0052 17.0 0.1 0.61 10.4 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain HI0933_like PF03486.14 KEY70580.1 - 0.95 8.1 6.9 2.9 6.5 0.1 3.4 3 1 1 4 4 4 0 HI0933-like protein Aminotran_3 PF00202.21 KEY70582.1 - 1.5e-53 182.0 0.0 1.8e-28 99.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III Cupin_3 PF05899.12 KEY70582.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DAO PF01266.24 KEY70583.1 - 2.7e-36 125.9 0.1 3.4e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY70583.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-HC5HC2H_2 PF13832.6 KEY70584.1 - 2.2e-20 72.8 1.3 2.2e-20 72.8 1.3 4.4 5 1 0 5 5 5 1 PHD-zinc-finger like domain BAH PF01426.18 KEY70584.1 - 1.2e-17 63.9 0.0 2.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KEY70584.1 - 2.1e-15 56.7 2.7 2.1e-15 56.7 2.7 4.8 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 KEY70584.1 - 1.7e-11 43.8 54.9 1.2e-06 28.3 7.2 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KEY70584.1 - 5e-10 38.8 4.1 5e-10 38.8 4.1 5.3 7 0 0 7 7 7 2 PHD-finger Myb_DNA-binding PF00249.31 KEY70584.1 - 0.00025 21.1 0.0 0.0007 19.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-RING_1 PF14446.6 KEY70584.1 - 0.0037 17.2 34.8 0.06 13.3 6.7 4.3 3 1 0 3 3 3 2 Prokaryotic RING finger family 1 C1_2 PF03107.16 KEY70584.1 - 0.07 13.5 0.2 0.07 13.5 0.2 7.1 8 0 0 8 8 8 0 C1 domain ELM2 PF01448.24 KEY70584.1 - 3.5 8.5 9.1 0.11 13.3 0.5 2.9 3 0 0 3 3 3 0 ELM2 domain Pkinase PF00069.25 KEY70585.1 - 9.1e-12 44.9 0.0 2.4e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70585.1 - 0.00071 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY70586.1 - 4.8e-13 49.1 0.0 7.9e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70586.1 - 2.9e-06 26.8 0.1 2.4e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_38N PF01074.22 KEY70587.1 - 1.5e-87 293.7 0.1 2.1e-87 293.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KEY70587.1 - 1.6e-50 172.2 0.5 4.6e-50 170.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KEY70587.1 - 1e-25 89.7 0.0 2.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KEY70587.1 - 5.9e-11 42.3 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MutS_V PF00488.21 KEY70588.1 - 4.3e-71 238.8 0.4 8.7e-71 237.9 0.2 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KEY70588.1 - 6.4e-49 166.8 4.9 1.1e-48 166.0 4.9 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KEY70588.1 - 1.8e-18 66.8 0.0 6e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KEY70588.1 - 1.6e-09 38.1 0.0 5.3e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KEY70588.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEY70588.1 - 0.17 12.3 0.2 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RL10P_insert PF17777.1 KEY70589.1 - 4.8e-23 80.9 0.0 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KEY70589.1 - 5.7e-23 81.3 5.4 5.7e-23 81.3 5.4 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 KEY70589.1 - 9e-22 77.1 0.1 2.3e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 WD40 PF00400.32 KEY70590.1 - 0.008 17.0 0.2 5.8 8.0 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.15 KEY70590.1 - 0.047 13.0 0.0 0.86 8.9 0.0 2.4 3 0 0 3 3 3 0 CPSF A subunit region DnaJ_C PF01556.18 KEY70591.1 - 3.6e-37 127.7 0.1 4.8e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEY70591.1 - 1.6e-28 98.6 1.9 2.6e-28 97.9 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEY70591.1 - 2.5e-16 59.8 18.0 4.2e-16 59.0 18.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEY70591.1 - 0.037 14.0 16.4 0.18 11.8 2.4 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Chorismate_bind PF00425.18 KEY70591.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 chorismate binding enzyme zinc_ribbon_9 PF14369.6 KEY70591.1 - 0.37 11.1 2.9 32 4.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 KEY70591.1 - 0.45 10.5 9.5 0.48 10.5 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KEY70591.1 - 0.48 10.5 7.6 21 5.2 7.9 2.4 1 1 0 1 1 1 0 zinc-ribbons DUF2614 PF11023.8 KEY70591.1 - 0.59 10.2 6.4 2.2 8.4 1.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF3425 PF11905.8 KEY70592.1 - 1.5e-18 66.9 0.1 2.6e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KEY70592.1 - 0.014 15.4 5.0 0.028 14.5 5.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KEY70592.1 - 0.027 14.6 3.9 0.06 13.5 3.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor CAP_GLY PF01302.25 KEY70593.1 - 9.2e-15 54.4 1.2 2.1e-14 53.3 0.8 1.9 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KEY70593.1 - 3.3e-07 30.0 11.9 0.0015 18.4 1.7 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 KEY70593.1 - 0.0051 15.7 27.1 0.037 12.9 1.2 3.4 2 1 2 4 4 4 3 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KEY70593.1 - 0.019 15.0 3.5 1.2 9.2 0.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glutaredoxin2_C PF04399.13 KEY70593.1 - 0.078 12.8 0.8 8 6.3 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain ATG16 PF08614.11 KEY70593.1 - 0.086 13.1 0.2 0.086 13.1 0.2 4.4 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KEY70593.1 - 0.31 11.5 8.3 12 6.5 0.1 3.8 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KEY70593.1 - 0.36 10.1 18.2 3.3e+03 -2.9 18.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 KEY70593.1 - 0.44 9.4 25.1 0.14 11.0 9.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Filament PF00038.21 KEY70593.1 - 0.64 9.5 30.0 0.38 10.3 0.7 3.2 1 1 1 3 3 3 0 Intermediate filament protein Fib_alpha PF08702.10 KEY70593.1 - 0.75 10.0 16.9 8.9 6.5 0.3 4.2 2 1 1 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KEY70593.1 - 1.4 8.9 11.4 3.4 7.7 1.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KEY70593.1 - 1.8 8.9 14.2 7.5 6.9 2.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF16 PF01519.16 KEY70593.1 - 1.8 9.1 12.4 8.2 7.0 0.1 4.2 2 1 1 4 4 4 0 Protein of unknown function DUF16 MAD PF05557.13 KEY70593.1 - 1.8 6.8 27.0 0.24 9.7 13.1 2.9 1 1 2 3 3 3 0 Mitotic checkpoint protein HemX PF04375.14 KEY70593.1 - 1.9 7.7 14.4 7.3 5.8 7.8 3.2 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_13 PF13166.6 KEY70593.1 - 2.6 6.6 20.7 0.025 13.2 9.4 2.4 1 1 0 2 2 2 0 AAA domain FAM76 PF16046.5 KEY70593.1 - 4 6.7 14.7 17 4.7 0.6 3.4 3 0 0 3 3 3 0 FAM76 protein HrpB7 PF09486.10 KEY70593.1 - 4.1 7.8 25.3 6.3 7.2 1.1 3.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 KEY70593.1 - 4.3 7.8 32.5 0.85 10.0 10.7 3.6 3 1 1 4 4 4 0 Fez1 BLOC1_2 PF10046.9 KEY70593.1 - 4.6 7.6 14.7 1 9.7 1.6 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KEY70593.1 - 6.9 5.9 15.4 0.24 10.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Nop14 PF04147.12 KEY70595.1 - 3.8e-290 965.1 31.4 5.1e-290 964.7 31.4 1.2 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.6 KEY70596.1 - 4.3e-22 77.6 1.7 1.5e-21 75.9 1.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KEY70596.1 - 1e-08 34.9 4.1 1.9e-08 34.0 4.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEY70596.1 - 0.3 11.2 6.2 0.11 12.5 2.2 2.4 2 0 0 2 2 2 0 G-patch domain Rimk_N PF18030.1 KEY70596.1 - 0.6 10.5 3.0 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 RimK PreATP-grasp domain SKA2 PF16740.5 KEY70597.1 - 0.82 9.5 9.6 5.7 6.8 4.3 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4200 PF13863.6 KEY70597.1 - 1 9.8 17.1 0.59 10.5 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 KEY70597.1 - 3.3 8.3 9.1 9 6.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 KEY70597.1 - 5.8 7.2 11.8 0.5 10.6 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KEY70597.1 - 8.2 6.9 14.1 7 7.2 0.4 3.4 1 1 1 2 2 2 0 Cell division protein ZapB HSP70 PF00012.20 KEY70598.1 - 6.5e-06 24.6 0.0 0.0039 15.4 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KEY70598.1 - 0.072 11.9 0.1 0.61 8.8 0.1 2.2 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.16 KEY70599.1 - 1.9e-24 86.3 43.4 1.1e-19 70.6 34.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY70599.1 - 0.14 10.5 15.4 0.0097 14.4 2.1 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HlyIII PF03006.20 KEY70600.1 - 4.3e-51 173.8 10.7 5.6e-51 173.4 10.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DnaJ PF00226.31 KEY70601.1 - 6.2e-11 42.3 0.1 1.2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Importin_rep PF18773.1 KEY70601.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat SirA PF10747.9 KEY70601.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Transformer PF06495.11 KEY70602.1 - 0.85 9.7 14.4 2 8.5 14.4 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Cgr1 PF03879.14 KEY70604.1 - 1.9e-31 108.6 31.0 2.2e-31 108.4 31.0 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.12 KEY70604.1 - 0.33 10.7 13.5 0.35 10.7 13.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRM13 PF05206.14 KEY70604.1 - 0.43 10.1 7.9 0.51 9.8 7.9 1.0 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF1682 PF07946.14 KEY70604.1 - 0.6 9.3 30.9 0.75 8.9 30.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.6 KEY70604.1 - 4.9 6.4 8.6 5.1 6.4 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 KEY70605.1 - 0.02 15.0 0.4 0.15 12.2 0.0 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KEY70605.1 - 0.028 14.6 2.9 0.11 12.7 1.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5623 PF18536.1 KEY70605.1 - 0.043 14.1 1.4 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Med4 PF10018.9 KEY70605.1 - 0.059 13.0 1.8 0.76 9.4 0.0 2.5 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.11 KEY70605.1 - 0.069 12.0 4.1 0.051 12.5 1.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2207 PF09972.9 KEY70605.1 - 0.09 11.5 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FlaC_arch PF05377.11 KEY70605.1 - 0.11 12.9 0.8 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 KEY70605.1 - 0.12 11.9 4.1 0.18 11.4 3.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC2_membrane_2 PF12679.7 KEY70605.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2205 PF10224.9 KEY70605.1 - 0.56 10.2 5.5 5.4 7.1 0.2 3.3 1 1 2 3 3 3 0 Short coiled-coil protein DivIC PF04977.15 KEY70605.1 - 2.1 8.1 5.7 8 6.3 0.5 2.9 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 KEY70605.1 - 6.1 7.4 9.7 9.4 6.8 0.5 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF3818 PF12825.7 KEY70606.1 - 1.4e-130 435.3 8.0 2.3e-130 434.6 8.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KEY70606.1 - 2.6e-39 134.2 0.9 5.2e-39 133.2 0.9 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KEY70606.1 - 5.8e-15 55.3 0.0 1.4e-13 50.9 0.0 3.0 2 1 0 2 2 2 1 PX domain GFD1 PF17331.2 KEY70606.1 - 0.14 12.4 2.2 0.45 10.8 2.2 1.9 1 0 0 1 1 1 0 GFD1 mRNA transport factor UPF0227 PF05728.12 KEY70606.1 - 0.3 11.0 1.7 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Acetyltransf_11 PF13720.6 KEY70606.1 - 1.2 9.6 3.6 3.7 8.1 1.1 2.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AP_endonuc_2 PF01261.24 KEY70607.1 - 1.5e-26 93.2 0.1 3.8e-26 91.8 0.0 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Exotox-A_cataly PF09009.10 KEY70607.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic zf-GRF PF06839.12 KEY70608.1 - 4.3e-08 33.1 7.4 8e-08 32.2 7.4 1.5 1 0 0 1 1 1 1 GRF zinc finger ADK PF00406.22 KEY70609.1 - 4.3e-44 150.3 0.0 5.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEY70609.1 - 1.4e-33 116.2 0.0 2.6e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY70609.1 - 4.6e-08 33.7 0.0 7.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEY70609.1 - 9.1e-07 29.1 0.0 3.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KEY70609.1 - 7.3e-05 22.5 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase PCI PF01399.27 KEY70610.1 - 1.3e-18 67.4 0.1 5e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KEY70610.1 - 2.1e-11 43.3 0.5 2.1e-11 43.3 0.5 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix PGA2 PF07543.12 KEY70610.1 - 0.029 14.3 3.2 0.035 14.1 0.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 KEY70611.1 - 1.6e-78 263.7 0.0 2.1e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70611.1 - 4.3e-39 134.4 0.0 6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEY70611.1 - 1e-16 61.0 0.4 1.9e-16 60.1 0.4 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KEY70611.1 - 2.7e-11 43.3 0.0 9.7e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 KEY70611.1 - 1.7e-09 37.9 0.0 3.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KEY70611.1 - 7.1e-06 25.1 0.0 9.4e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEY70611.1 - 0.0095 15.6 0.5 1.1 8.9 0.1 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KEY70611.1 - 0.042 12.8 0.2 0.085 11.8 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KEY70611.1 - 0.044 13.1 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KEY70611.1 - 0.055 13.0 0.2 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FHA_2 PF17913.1 KEY70611.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 FHA domain ArfGap PF01412.18 KEY70612.1 - 2.6e-33 114.6 0.6 7.3e-33 113.1 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KEY70612.1 - 4.1e-19 69.2 12.9 6.3e-19 68.6 12.9 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KEY70612.1 - 9.8e-12 45.3 0.1 2.8e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 PH domain ANAPC9 PF12856.7 KEY70612.1 - 0.051 13.8 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 AAA_24 PF13479.6 KEY70612.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain C2 PF00168.30 KEY70613.1 - 8.3e-17 61.4 0.0 1.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KEY70613.1 - 1.8e-15 57.4 0.4 2.1e-12 47.5 0.4 2.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 KEY70613.1 - 3.1e-06 26.0 0.2 5.9e-06 25.1 0.2 1.4 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) ERp29 PF07749.12 KEY70613.1 - 0.069 14.0 2.4 0.48 11.3 0.8 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SopA PF13981.6 KEY70613.1 - 0.82 10.1 4.3 0.93 9.9 0.6 2.9 2 1 1 3 3 3 0 SopA-like central domain HAMP PF00672.25 KEY70614.1 - 3e-39 133.2 21.1 2.1e-08 34.4 0.2 7.8 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.26 KEY70614.1 - 4.3e-31 107.7 0.7 1.6e-30 105.9 0.2 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY70614.1 - 2.5e-25 88.8 0.3 2.5e-25 88.8 0.3 2.9 3 0 0 3 3 2 1 Response regulator receiver domain HisKA PF00512.25 KEY70614.1 - 9.1e-17 60.9 0.5 9.1e-17 60.9 0.5 4.4 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KEY70614.1 - 0.00051 20.4 16.6 2.5 8.5 0.1 7.1 4 3 3 8 8 7 2 Syntaxin-like protein Fib_alpha PF08702.10 KEY70614.1 - 0.0011 19.1 28.1 0.18 12.0 0.3 6.7 6 1 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF4279 PF14106.6 KEY70614.1 - 0.011 15.9 0.0 35 4.7 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) GLE1 PF07817.13 KEY70614.1 - 0.024 13.9 2.4 14 4.8 0.0 4.2 3 1 1 4 4 4 0 GLE1-like protein DUF948 PF06103.11 KEY70614.1 - 0.044 14.1 41.3 0.6 10.4 1.8 9.8 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) HTH_6 PF01418.17 KEY70614.1 - 0.1 12.6 0.0 11 6.1 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family PMC2NT PF08066.12 KEY70614.1 - 0.23 12.2 7.7 3.9 8.2 1.8 4.7 3 1 1 4 4 4 0 PMC2NT (NUC016) domain DUF4795 PF16043.5 KEY70614.1 - 0.48 10.0 25.3 7.2 6.2 4.9 5.9 1 1 1 4 4 4 0 Domain of unknown function (DUF4795) BORCS6 PF10157.9 KEY70614.1 - 0.55 10.4 9.3 2.2 8.5 0.2 4.9 2 2 1 4 4 4 0 BLOC-1-related complex sub-unit 6 GhoS PF11080.8 KEY70614.1 - 0.75 9.8 5.8 1.6 8.7 0.1 3.4 3 0 0 3 3 3 0 Endoribonuclease GhoS DUF3829 PF12889.7 KEY70614.1 - 2.4 7.5 8.0 3.2 7.2 0.2 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF3829) DUF883 PF05957.13 KEY70614.1 - 2.7 8.7 18.9 2.8 8.6 0.3 6.3 5 2 2 7 7 6 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 KEY70615.1 - 0.033 14.2 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus KIP1 PF07765.12 KEY70615.1 - 0.069 13.3 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 KIP1-like protein CLZ PF16526.5 KEY70615.1 - 0.085 13.2 0.4 0.085 13.2 0.4 1.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HMG_box PF00505.19 KEY70616.1 - 2.4e-12 47.1 3.3 1.6e-09 38.0 1.1 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box SAM_1 PF00536.30 KEY70616.1 - 1.6e-10 41.3 0.0 2.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KEY70616.1 - 6e-09 36.4 2.0 6e-09 36.4 2.0 2.9 2 1 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 KEY70616.1 - 2.6e-07 30.6 0.0 6.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cnd2 PF05786.14 KEY70617.1 - 0 1077.9 0.9 0 1077.6 0.9 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KEY70617.1 - 0.012 15.9 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 KEY70618.1 - 4.1e-51 172.9 42.4 3.3e-27 95.3 18.1 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Pex14_N PF04695.13 KEY70618.1 - 0.071 13.8 4.7 0.09 13.4 0.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MARVEL PF01284.23 KEY70618.1 - 5.7 7.0 27.5 0.091 12.8 0.7 4.4 2 2 2 4 4 4 0 Membrane-associating domain PMM PF03332.13 KEY70619.1 - 1.7e-101 338.6 0.1 2e-101 338.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KEY70619.1 - 8.6e-05 22.4 0.0 0.00083 19.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY70619.1 - 0.1 13.0 0.0 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CTV_P13 PF06922.11 KEY70619.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein WW PF00397.26 KEY70620.1 - 2.7e-10 40.1 0.1 6.5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KEY70620.1 - 0.0041 16.2 0.1 0.0071 15.4 0.1 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase MutS_V PF00488.21 KEY70621.1 - 2.4e-72 242.9 0.8 3.7e-72 242.3 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KEY70621.1 - 5e-35 121.5 2.4 5e-35 121.5 2.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KEY70621.1 - 9e-29 100.0 0.0 2.1e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KEY70621.1 - 1.7e-09 38.1 0.2 1.6e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KEY70621.1 - 2.2e-06 27.9 0.1 6e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KEY70621.1 - 0.0068 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) AAA_28 PF13521.6 KEY70621.1 - 0.051 13.8 1.8 2.8 8.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KEY70621.1 - 0.092 13.2 0.2 0.85 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY70621.1 - 0.17 11.6 0.1 0.44 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C2H2_2 PF12756.7 KEY70622.1 - 0.048 14.0 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SSDP PF04503.13 KEY70622.1 - 6 7.1 10.7 0.054 13.8 0.9 2.1 2 1 0 2 2 2 0 Single-stranded DNA binding protein, SSDP Prenyltrans PF00432.21 KEY70623.1 - 5.9e-64 211.5 6.6 5.8e-13 48.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KEY70623.1 - 8.3e-06 25.1 0.1 0.21 10.7 0.0 3.1 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KEY70623.1 - 5.8e-05 22.3 0.0 0.03 13.4 0.0 3.1 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain DUF630 PF04783.12 KEY70623.1 - 0.037 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) RhoGAP PF00620.27 KEY70624.1 - 2.8e-29 101.9 0.0 4.9e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 KEY70625.1 - 6e-58 195.3 5.1 8.1e-58 194.9 5.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF1244 PF06844.11 KEY70625.1 - 0.3 11.3 1.7 0.69 10.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) DAP3 PF10236.9 KEY70626.1 - 2.2e-85 286.6 0.0 2.8e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KEY70626.1 - 0.064 13.0 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KEY70626.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCM PF00493.23 KEY70627.1 - 3.2e-104 346.9 0.0 5.5e-104 346.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEY70627.1 - 4.8e-29 100.8 0.4 8.4e-29 100.0 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEY70627.1 - 8.2e-21 74.2 1.2 1.8e-20 73.2 1.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEY70627.1 - 2.2e-18 66.8 0.7 2.2e-18 66.8 0.7 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEY70627.1 - 3.4e-08 33.1 0.0 1e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEY70627.1 - 1.3e-05 25.2 0.0 5.2e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KEY70627.1 - 0.0016 18.3 0.1 0.0049 16.7 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 KEY70627.1 - 0.0075 16.9 0.3 0.0075 16.9 0.3 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KEY70627.1 - 0.016 15.1 0.0 0.057 13.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEY70627.1 - 0.13 11.9 0.1 0.67 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KEY70628.1 - 7.1e-58 194.7 0.0 3.4e-43 147.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KEY70628.1 - 9.7e-28 96.4 1.3 2.4e-27 95.1 1.3 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KEY70628.1 - 1.4e-13 50.4 0.2 9.2e-09 35.0 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KEY70628.1 - 2e-10 41.3 9.2 2.5e-06 28.0 0.2 4.6 3 2 0 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KEY70628.1 - 5.7e-08 32.8 0.5 3.4e-05 23.8 0.0 3.4 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 KEY70628.1 - 5e-07 30.0 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEY70628.1 - 1.4e-06 28.9 0.0 0.0024 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEY70628.1 - 2e-06 27.7 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KEY70628.1 - 2.5e-06 27.6 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY70628.1 - 2.7e-06 27.7 2.3 0.039 14.2 0.1 4.3 3 2 1 4 4 4 2 AAA domain TsaE PF02367.17 KEY70628.1 - 4e-06 26.8 0.0 0.0055 16.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEY70628.1 - 5.4e-06 26.6 0.1 0.17 12.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KEY70628.1 - 6.1e-06 26.3 0.1 0.021 14.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEY70628.1 - 1.3e-05 24.8 0.0 0.00033 20.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEY70628.1 - 0.00011 22.0 0.2 0.065 13.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEY70628.1 - 0.00016 21.9 0.1 0.13 12.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.13 KEY70628.1 - 0.0007 18.9 0.0 0.79 8.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain SKI PF01202.22 KEY70628.1 - 0.0009 19.4 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.22 KEY70628.1 - 0.00092 19.6 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 KEY70628.1 - 0.00098 18.9 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KEY70628.1 - 0.0013 18.0 0.1 0.27 10.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 KEY70628.1 - 0.0016 17.9 0.1 0.95 8.8 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KEY70628.1 - 0.0018 18.7 0.4 2.9 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 KEY70628.1 - 0.002 17.8 0.0 0.069 12.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KEY70628.1 - 0.0022 17.6 0.2 7.3 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 KEY70628.1 - 0.0033 17.6 0.0 0.096 12.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KEY70628.1 - 0.0067 16.9 0.1 1.7 9.2 0.0 3.0 3 0 0 3 3 2 1 ABC transporter ATPase PF06745.13 KEY70628.1 - 0.013 14.8 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 KEY70628.1 - 0.014 15.3 0.1 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase ATPase_2 PF01637.18 KEY70628.1 - 0.024 14.6 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KEY70628.1 - 0.026 14.4 0.0 8.8 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KEY70628.1 - 0.03 14.4 0.0 9.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF815 PF05673.13 KEY70628.1 - 0.031 13.4 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 KEY70628.1 - 0.084 12.1 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KEY70628.1 - 0.1 12.3 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KEY70628.1 - 0.1 12.0 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.14 KEY70628.1 - 0.14 11.4 0.7 1.7 7.8 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 KEY70628.1 - 0.15 11.2 0.3 15 4.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 KEY70628.1 - 0.18 11.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KEY70628.1 - 0.19 11.3 1.3 2 8.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEY70628.1 - 0.22 11.2 0.1 4.9 6.9 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF4695 PF15766.5 KEY70629.1 - 0.083 13.1 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Zot PF05707.12 KEY70629.1 - 0.095 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Inositol_P PF00459.25 KEY70630.1 - 4e-42 144.6 0.0 8.8e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family SNF2_N PF00176.23 KEY70631.1 - 2.3e-54 184.4 0.0 3.8e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KEY70631.1 - 1.8e-26 91.8 6.8 1.7e-16 59.9 0.7 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KEY70631.1 - 2e-18 66.7 0.0 4.7e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KEY70631.1 - 3.4e-18 65.9 0.0 2e-17 63.4 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KEY70631.1 - 3.4e-09 36.3 0.0 1.3e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KEY70631.1 - 2.8e-06 27.6 0.2 2.8e-06 27.6 0.2 4.9 4 1 1 5 5 5 1 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 KEY70631.1 - 0.00034 20.6 0.7 0.0017 18.3 0.0 2.7 2 0 0 2 2 2 1 SLIDE CDH1_2_SANT_HL1 PF18375.1 KEY70631.1 - 0.00084 20.0 1.1 0.00084 20.0 1.1 3.0 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ResIII PF04851.15 KEY70631.1 - 0.0039 17.2 0.0 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KEY70632.1 - 4.5e-33 114.7 0.0 3.7e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KEY70632.1 - 4.3e-12 45.6 4.4 4.3e-12 45.6 4.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KEY70632.1 - 9.1e-12 44.9 0.3 0.00015 21.3 0.0 3.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEY70632.1 - 4e-11 43.3 3.1 0.13 12.0 1.1 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEY70632.1 - 7.6e-06 25.9 0.0 0.25 11.0 0.0 3.0 3 1 0 4 4 4 2 AAA ATPase domain Fer4 PF00037.27 KEY70632.1 - 1.1e-05 25.0 2.7 1.1e-05 25.0 2.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 KEY70632.1 - 1.1e-05 25.8 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY70632.1 - 1.4e-05 25.4 0.0 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY70632.1 - 2.9e-05 24.5 0.0 0.018 15.4 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KEY70632.1 - 9.1e-05 23.0 0.1 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 KEY70632.1 - 9.4e-05 22.5 8.3 0.0051 16.9 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEY70632.1 - 0.00045 20.3 9.8 0.00087 19.4 9.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 KEY70632.1 - 0.00052 20.6 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY70632.1 - 0.00058 19.8 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KEY70632.1 - 0.00058 19.6 0.2 0.68 9.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEY70632.1 - 0.00065 20.1 0.1 0.32 11.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KEY70632.1 - 0.00075 19.5 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 KEY70632.1 - 0.0018 18.0 0.6 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY70632.1 - 0.002 18.1 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 KEY70632.1 - 0.0029 17.3 2.1 0.13 11.9 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 KEY70632.1 - 0.0036 17.3 1.7 0.0036 17.3 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 KEY70632.1 - 0.0041 17.3 0.1 0.76 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KEY70632.1 - 0.0069 17.0 6.8 0.013 16.1 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain TsaE PF02367.17 KEY70632.1 - 0.0072 16.3 0.1 0.074 13.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KEY70632.1 - 0.0076 15.0 2.1 0.0086 14.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KEY70632.1 - 0.0092 15.5 0.8 0.1 12.1 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KEY70632.1 - 0.017 14.8 0.9 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_28 PF13521.6 KEY70632.1 - 0.025 14.8 0.1 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEY70632.1 - 0.036 14.1 1.4 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_9 PF13187.6 KEY70632.1 - 0.04 14.1 10.2 0.084 13.0 10.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KEY70632.1 - 0.048 13.4 0.2 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEY70632.1 - 0.049 12.8 0.0 6.4 5.9 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Fer4_16 PF13484.6 KEY70632.1 - 0.11 13.4 0.3 0.11 13.4 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KEY70632.1 - 0.16 12.1 0.8 18 5.4 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 KEY70632.1 - 0.17 11.6 0.0 7.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E PduV-EutP PF10662.9 KEY70632.1 - 0.33 10.7 3.2 0.71 9.6 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KEY70632.1 - 0.36 10.7 1.8 7.4 6.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_2 PF12797.7 KEY70632.1 - 1.2 9.3 10.2 0.33 11.1 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 KEY70633.1 - 2.2e-46 155.8 12.7 8.3e-13 48.3 0.2 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.26 KEY70633.1 - 1e-17 63.9 18.3 1.2e-09 38.1 5.1 2.7 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KEY70633.1 - 0.18 12.1 5.2 3.6 7.9 0.3 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Lipin_mid PF16876.5 KEY70633.1 - 0.26 11.5 1.0 6.9 6.9 0.0 2.7 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RhoGAP-FF1 PF16512.5 KEY70633.1 - 0.44 11.3 13.7 10 6.9 0.0 5.3 4 1 2 6 6 6 0 p190-A and -B Rho GAPs FF domain Trs65 PF12735.7 KEY70634.1 - 1.3e-121 405.9 0.0 1.8e-121 405.4 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.10 KEY70635.1 - 1.8e-158 528.7 0.1 2.6e-158 528.2 0.1 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Homeodomain PF00046.29 KEY70636.1 - 9.1e-15 54.3 3.1 2.2e-14 53.0 3.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEY70636.1 - 0.004 17.0 0.9 0.01 15.7 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain Na_trans_assoc PF06512.13 KEY70636.1 - 1.1 9.4 7.8 1.8 8.8 7.8 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4551 PF15087.6 KEY70636.1 - 4.1 6.1 10.5 5.4 5.7 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HAD_2 PF13419.6 KEY70637.1 - 9.6e-20 71.4 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY70637.1 - 2.6e-10 40.9 0.0 2.1e-05 24.9 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY70637.1 - 3.5e-05 24.3 0.0 5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY70637.1 - 5.3e-05 23.2 0.0 9.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KEY70637.1 - 0.0068 16.5 0.1 0.082 13.0 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 KEY70637.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Peptidase_C15 PF01470.17 KEY70638.1 - 8.1e-10 39.2 0.0 0.00013 22.2 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase Rhabdo_glycop PF00974.18 KEY70639.1 - 0.88 8.0 3.7 0.86 8.0 3.7 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4110 PF13422.6 KEY70640.1 - 2e-30 104.7 1.3 2e-30 104.7 1.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KEY70640.1 - 1.2e-25 89.3 12.3 6.2e-07 29.3 0.0 6.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY70640.1 - 1.8e-22 79.1 10.9 2.6e-06 27.6 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEY70640.1 - 5.7e-17 61.3 1.8 6.1e-06 26.1 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KEY70640.1 - 4.1e-15 55.1 2.8 7.9e-06 25.7 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KEY70640.1 - 3.8e-13 49.2 1.9 0.0097 16.2 0.2 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KEY70640.1 - 2.5e-11 43.0 0.7 0.0033 17.0 0.1 5.0 5 0 0 5 5 5 3 Kelch motif PTPRCAP PF15713.5 KEY70640.1 - 0.0073 16.6 12.0 0.0073 16.6 12.0 3.3 3 0 0 3 3 3 1 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 KEY70640.1 - 0.32 10.3 30.0 0.034 13.5 13.2 2.2 2 0 0 2 2 2 0 BUD22 Methyltransf_15 PF09445.10 KEY70641.1 - 4.6e-42 143.4 0.0 6.1e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KEY70641.1 - 0.00068 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KEY70641.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KEY70641.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KEY70641.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KEY70641.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family GRASP55_65 PF04495.14 KEY70642.1 - 2.6e-47 160.6 0.0 7e-46 156.0 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KEY70642.1 - 0.0016 18.2 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain DAD PF02109.16 KEY70643.1 - 2.3e-50 169.5 2.5 2.7e-50 169.2 2.5 1.0 1 0 0 1 1 1 1 DAD family DEC-1_N PF04625.13 KEY70643.1 - 1.1 8.2 4.7 1.4 7.9 4.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Tmemb_14 PF03647.13 KEY70644.1 - 4.3e-23 81.9 7.1 4.9e-23 81.7 7.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.10 KEY70645.1 - 3.4e-16 59.0 4.6 4.1e-16 58.8 4.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 KEY70645.1 - 1.2 9.6 4.2 3.1 8.2 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Prefoldin_2 PF01920.20 KEY70646.1 - 4.3e-25 87.7 8.9 5e-25 87.5 8.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit PhaP_Bmeg PF09602.10 KEY70646.1 - 0.002 18.1 1.6 0.021 14.8 0.1 2.0 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Prefoldin PF02996.17 KEY70646.1 - 0.035 14.0 6.8 0.13 12.2 0.5 2.2 1 1 0 2 2 2 0 Prefoldin subunit CBFD_NFYB_HMF PF00808.23 KEY70647.1 - 2e-26 92.0 1.6 5.6e-26 90.6 1.4 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY70647.1 - 6.7e-07 29.7 0.4 1.4e-06 28.7 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KEY70647.1 - 0.0012 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KEY70647.1 - 0.0019 18.2 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KEY70647.1 - 0.016 15.3 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KEY70647.1 - 0.052 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RRN3 PF05327.11 KEY70648.1 - 3.2e-173 577.3 0.0 5.2e-173 576.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.21 KEY70649.1 - 0.48 10.6 11.3 1.7 8.8 11.0 1.9 1 1 1 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 KEY70649.1 - 0.58 10.6 6.8 0.41 11.1 5.1 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Dopey_N PF04118.14 KEY70650.1 - 1.7e-115 385.3 0.0 3.6e-115 384.3 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Mon1 PF03164.14 KEY70651.1 - 1e-151 505.7 0.0 1.2e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Exo_endo_phos_2 PF14529.6 KEY70651.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase COesterase PF00135.28 KEY70654.1 - 4.5e-80 269.9 0.0 5.3e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY70654.1 - 0.0054 16.6 0.8 0.014 15.2 0.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Het-C PF07217.11 KEY70655.1 - 0.15 10.6 1.5 0.18 10.3 1.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C F-box-like PF12937.7 KEY70656.1 - 0.00066 19.5 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like EspF PF04806.12 KEY70656.1 - 0.39 11.2 17.2 2.9 8.4 3.9 3.4 2 0 0 2 2 2 0 EspF protein repeat TMEM154 PF15102.6 KEY70657.1 - 0.00011 22.1 0.4 0.00028 20.8 0.4 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 KEY70657.1 - 0.0018 18.7 2.7 0.0018 18.7 2.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Glycophorin_A PF01102.18 KEY70657.1 - 0.0026 18.0 0.1 0.0061 16.8 0.1 1.7 1 0 0 1 1 1 1 Glycophorin A DUF2407_C PF13373.6 KEY70657.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain RIFIN PF02009.16 KEY70657.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF2207 PF09972.9 KEY70657.1 - 0.19 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lustrin_cystein PF14625.6 KEY70657.1 - 0.46 10.9 18.1 1.6 9.2 2.3 2.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Podoplanin PF05808.11 KEY70657.1 - 3.3 7.8 11.1 2.2 8.3 8.6 1.8 1 1 1 2 2 2 0 Podoplanin Fungal_trans_2 PF11951.8 KEY70659.1 - 5.3e-87 292.1 1.5 6.8e-87 291.8 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70659.1 - 2.3e-08 34.0 6.6 3.7e-08 33.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.17 KEY70661.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KEY70661.1 - 4.4e-05 24.0 0.0 0.00016 22.2 0.0 2.0 1 0 0 1 1 1 1 PH domain Sod_Fe_C PF02777.18 KEY70662.1 - 6.6e-14 51.9 0.0 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain STIMATE PF12400.8 KEY70663.1 - 1.6e-40 138.5 3.2 1.6e-40 138.5 3.2 1.8 2 0 0 2 2 2 1 STIMATE family RCR PF12273.8 KEY70665.1 - 1.7e-20 73.8 26.2 4.4e-19 69.3 26.2 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.8 KEY70665.1 - 0.055 14.1 1.7 0.13 12.9 1.7 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 TMEM132D_C PF15706.5 KEY70665.1 - 0.21 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Rhabdo_glycop PF00974.18 KEY70665.1 - 0.28 9.6 1.2 0.4 9.1 1.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Pex14_N PF04695.13 KEY70665.1 - 0.68 10.6 5.5 1 10.0 5.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAD_binding_3 PF01494.19 KEY70666.1 - 9.8e-23 81.0 0.0 2.5e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY70666.1 - 9.3e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY70666.1 - 0.00027 21.1 0.2 0.00094 19.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY70666.1 - 0.00089 18.6 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY70666.1 - 0.0047 16.0 0.4 0.04 13.0 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEY70666.1 - 0.0068 15.5 0.9 0.014 14.5 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEY70666.1 - 0.0077 15.5 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KEY70666.1 - 0.017 14.0 0.9 0.091 11.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KEY70666.1 - 0.043 13.1 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KEY70666.1 - 0.052 14.1 0.6 0.11 13.0 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY70666.1 - 0.065 12.5 0.2 0.12 11.5 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 KEY70667.1 - 4.7e-30 104.9 0.0 1.5e-29 103.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA_synt_1c_R2 PF04557.15 KEY70668.1 - 0.015 16.2 1.2 0.037 14.9 1.2 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CPSase_L_D2 PF02786.17 KEY70669.1 - 1.1e-80 270.2 0.4 1.6e-80 269.6 0.4 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KEY70669.1 - 2.7e-68 229.7 0.0 4.5e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KEY70669.1 - 1e-38 132.3 0.0 2e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEY70669.1 - 4.7e-32 110.3 0.0 1.8e-31 108.4 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KEY70669.1 - 1.2e-25 90.6 0.0 2.3e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KEY70669.1 - 9.5e-19 67.0 0.6 2.5e-18 65.7 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEY70669.1 - 2e-11 43.5 0.7 2.4e-06 27.3 0.0 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KEY70669.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEY70669.1 - 1.9e-07 30.8 0.1 3.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KEY70669.1 - 3e-05 23.3 0.1 0.035 13.3 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KEY70669.1 - 0.00038 20.5 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KEY70669.1 - 0.00056 20.6 0.1 3.3 8.5 0.0 3.2 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.11 KEY70669.1 - 0.0011 18.6 0.0 0.0047 16.5 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain DUF2118 PF09891.9 KEY70669.1 - 0.014 15.3 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 KEY70669.1 - 0.017 14.6 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 KEY70669.1 - 0.019 14.7 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 KEY70669.1 - 0.041 13.8 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 KEY70669.1 - 0.043 13.1 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KEY70669.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KEY70669.1 - 0.13 11.5 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp FAD_binding_2 PF00890.24 KEY70670.1 - 8.9e-123 410.4 3.9 1.1e-122 410.1 3.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEY70670.1 - 1e-44 151.6 0.8 1.5e-44 151.1 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KEY70670.1 - 4.8e-06 26.0 1.2 0.0027 17.0 0.4 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY70670.1 - 0.00014 21.2 0.2 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KEY70670.1 - 0.00015 21.0 1.3 0.046 12.8 1.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KEY70670.1 - 0.003 16.8 0.1 0.003 16.8 0.1 2.0 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KEY70670.1 - 0.16 11.5 1.7 0.31 10.6 1.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY70670.1 - 0.26 9.9 0.6 0.97 8.1 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein EXS PF03124.14 KEY70671.1 - 3e-116 388.3 11.8 3.5e-116 388.2 11.8 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 KEY70672.1 - 1.4e-33 116.3 2.2 1.8e-33 116.0 2.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KEY70672.1 - 5.8e-12 45.2 8.6 9e-12 44.6 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY70672.1 - 3.3e-11 43.3 8.6 5.1e-11 42.7 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEY70672.1 - 2.5e-10 40.0 6.1 3.8e-10 39.5 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY70672.1 - 7.7e-10 38.5 6.7 1.2e-09 37.9 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY70672.1 - 9.9e-08 31.9 7.1 1.9e-07 31.0 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEY70672.1 - 1.9e-07 30.9 5.4 3.1e-07 30.2 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KEY70672.1 - 2.3e-07 31.0 6.0 4.2e-07 30.2 6.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KEY70672.1 - 4.6e-07 29.6 6.8 7.4e-07 28.9 6.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEY70672.1 - 1.7e-06 28.1 8.3 2.8e-06 27.4 8.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KEY70672.1 - 0.00012 21.9 1.8 0.00022 21.0 1.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KEY70672.1 - 0.00051 20.1 5.0 0.00083 19.4 5.0 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KEY70672.1 - 0.0058 16.4 2.1 0.0099 15.7 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KEY70672.1 - 0.049 13.7 2.2 0.089 12.9 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KEY70672.1 - 0.053 13.3 6.2 0.12 12.2 6.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KEY70672.1 - 0.15 11.8 3.3 0.33 10.7 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KEY70672.1 - 0.84 9.3 5.7 1.5 8.5 5.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-LYAR PF08790.11 KEY70673.1 - 0.015 15.2 2.2 0.24 11.4 0.3 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger 2OG-FeII_Oxy_5 PF13759.6 KEY70673.1 - 0.11 12.9 1.4 14 6.1 1.2 2.6 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Hydrolase_4 PF12146.8 KEY70675.1 - 2.5e-16 59.7 0.0 7.3e-11 41.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY70675.1 - 2.6e-11 43.7 0.2 6.1e-07 29.3 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY70675.1 - 1.4e-05 25.8 0.1 0.00073 20.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 KEY70675.1 - 0.00035 19.6 0.1 0.00051 19.1 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KEY70675.1 - 0.00047 19.9 0.0 0.0015 18.3 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KEY70675.1 - 0.00053 19.5 0.0 0.0033 16.9 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KEY70675.1 - 0.0076 15.0 0.0 4 6.0 0.0 2.8 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 KEY70675.1 - 0.014 15.0 0.0 0.25 10.9 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KEY70675.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold R3H PF01424.22 KEY70676.1 - 5.3e-16 58.4 0.3 1e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 R3H domain Zf_RING PF16744.5 KEY70676.1 - 0.0012 18.9 6.4 0.0012 18.9 6.4 3.2 3 0 0 3 3 3 2 KIAA1045 RING finger zf-NF-X1 PF01422.17 KEY70676.1 - 0.0015 18.5 10.8 0.0015 18.5 10.8 5.8 7 0 0 7 7 7 2 NF-X1 type zinc finger WSC PF01822.19 KEY70677.1 - 3.7e-69 228.9 56.9 3.9e-20 71.8 7.2 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KEY70677.1 - 1.2e-26 93.4 0.0 4.4e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KEY70677.1 - 1.7e-20 73.1 0.0 3.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF659 PF04937.15 KEY70678.1 - 0.044 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) SnoaL PF07366.12 KEY70679.1 - 9.9e-20 70.6 0.1 3.4e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY70679.1 - 1.5e-08 35.2 0.1 4.5e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain P16-Arc PF04699.14 KEY70679.1 - 0.13 12.8 0.1 0.24 11.9 0.0 1.5 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Vta1 PF04652.16 KEY70679.1 - 0.22 11.5 0.6 1.2 9.1 0.1 2.0 2 0 0 2 2 2 0 Vta1 like zf-CCHC PF00098.23 KEY70682.1 - 0.002 18.1 2.0 0.0046 17.0 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF5327 PF17261.2 KEY70682.1 - 1.5 9.6 4.1 3.4 8.5 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Nic96 PF04097.14 KEY70683.1 - 8.4e-221 734.7 0.0 1e-220 734.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KEY70683.1 - 0.0014 19.5 78.0 0.017 15.9 49.0 4.2 2 1 1 3 3 3 1 Nucleoporin FG repeat region DUF4396 PF14342.6 KEY70683.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) FGGY_C PF02782.16 KEY70684.1 - 2.2e-46 158.1 0.3 3.5e-46 157.4 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEY70684.1 - 4.2e-22 78.9 0.1 1.4e-20 74.0 0.1 2.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain VTC PF09359.10 KEY70685.1 - 5.6e-87 291.6 1.4 9.3e-87 290.9 1.4 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KEY70685.1 - 1.9e-11 44.3 2.6 3.6e-11 43.4 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KEY70685.1 - 2.8e-05 24.2 6.6 0.00038 20.5 1.0 4.5 3 1 2 5 5 5 2 SPX domain PRIMA1 PF16101.5 KEY70685.1 - 0.047 13.7 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GATase_2 PF00310.21 KEY70686.1 - 1.9e-182 606.7 0.0 2.6e-182 606.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KEY70686.1 - 6.1e-156 519.2 0.0 1.1e-155 518.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KEY70686.1 - 3.4e-111 371.2 0.0 8.5e-110 366.6 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KEY70686.1 - 7.1e-87 289.9 1.5 1.3e-86 289.1 1.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KEY70686.1 - 5.4e-23 81.7 0.2 1.9e-22 79.9 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KEY70686.1 - 5.8e-21 74.4 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KEY70686.1 - 3e-08 33.8 0.0 1.1e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY70686.1 - 7.4e-08 32.8 0.3 0.00075 20.0 0.1 3.4 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY70686.1 - 1.5e-07 31.3 1.0 0.00068 19.3 0.3 2.9 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY70686.1 - 5.6e-06 25.8 0.9 0.045 13.0 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY70686.1 - 9.3e-06 25.2 0.1 2.1e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KEY70686.1 - 4.5e-05 22.3 0.1 9.7e-05 21.2 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KEY70686.1 - 0.00047 19.6 0.3 0.00093 18.7 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY70686.1 - 0.00075 18.7 0.1 0.0026 16.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEY70686.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KEY70686.1 - 0.011 16.2 1.8 5.9 7.4 0.1 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding FMO-like PF00743.19 KEY70686.1 - 0.012 14.1 0.1 0.95 7.8 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 KEY70686.1 - 0.017 14.2 1.0 0.12 11.4 1.1 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.21 KEY70686.1 - 0.017 14.4 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KEY70686.1 - 0.024 13.9 0.2 0.077 12.2 0.2 1.8 1 0 0 1 1 1 0 Thi4 family GATase_6 PF13522.6 KEY70686.1 - 0.09 13.0 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase domain AdoHcyase_NAD PF00670.21 KEY70686.1 - 0.098 12.7 0.3 9.8 6.2 0.1 3.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.12 KEY70686.1 - 0.13 11.3 0.1 0.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KEY70686.1 - 0.2 11.6 0.1 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KEY70686.1 - 0.79 8.7 2.1 0.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Apc15p PF05841.11 KEY70688.1 - 4e-20 72.9 3.5 9.7e-19 68.4 0.1 2.9 2 1 1 3 3 3 2 Apc15p protein Na_trans_assoc PF06512.13 KEY70688.1 - 8.2 6.7 16.3 19 5.5 16.3 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated CHZ PF09649.10 KEY70689.1 - 8.4e-17 60.3 0.9 8.4e-17 60.3 0.9 2.3 3 0 0 3 3 3 1 Histone chaperone domain CHZ Use1 PF09753.9 KEY70689.1 - 4.7e-05 23.2 0.0 8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 BUD22 PF09073.10 KEY70689.1 - 0.11 11.8 14.0 0.15 11.4 14.0 1.3 1 0 0 1 1 1 0 BUD22 Cyclin PF08613.11 KEY70691.1 - 1.7e-31 109.8 0.0 1.7e-31 109.8 0.0 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KEY70691.1 - 9.5e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 KEY70692.1 - 8.4e-06 25.7 9.7 0.098 12.7 0.1 7.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KEY70692.1 - 0.00072 19.6 15.7 0.8 10.1 0.1 7.4 7 1 1 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 KEY70692.1 - 0.0019 18.6 19.2 0.19 12.3 0.1 5.9 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 KEY70692.1 - 0.0073 16.7 14.4 0.99 9.8 0.2 6.5 6 1 0 6 6 6 1 HEAT repeats PUL PF08324.11 KEY70692.1 - 0.027 13.7 0.0 8.1 5.6 0.1 2.8 2 0 0 2 2 2 0 PUL domain Csm1_N PF18504.1 KEY70692.1 - 0.15 12.4 0.3 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Velvet PF11754.8 KEY70693.1 - 1.6e-51 175.6 8.7 2e-32 113.1 0.0 3.3 2 2 1 3 3 3 2 Velvet factor TIG PF01833.24 KEY70695.1 - 1.2e-08 34.9 0.0 4.2e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 IPT/TIG domain DUF4680 PF15730.5 KEY70695.1 - 0.16 12.3 1.3 0.45 10.9 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) RNase_H PF00075.24 KEY70696.1 - 9.3e-37 126.4 0.0 1.9e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KEY70696.1 - 6.9e-35 119.1 9.7 1.4e-17 63.7 2.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin dCMP_cyt_deam_1 PF00383.23 KEY70697.1 - 3.9e-07 29.9 0.0 8e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY70697.1 - 0.0031 17.2 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase 6PF2K PF01591.18 KEY70698.1 - 3.1e-65 219.6 0.0 3e-45 154.3 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEY70698.1 - 4.1e-30 104.9 0.0 2e-24 86.4 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KEY70698.1 - 0.0064 16.7 0.1 0.073 13.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain CARD PF00619.21 KEY70698.1 - 0.018 15.1 0.1 0.063 13.3 0.1 1.9 1 1 0 1 1 1 0 Caspase recruitment domain KTI12 PF08433.10 KEY70698.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sof1 PF04158.14 KEY70699.1 - 2.6e-32 110.9 15.9 5.6e-32 109.9 15.9 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KEY70699.1 - 1.2e-30 105.1 7.0 1.7e-05 25.5 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY70699.1 - 3e-08 33.9 0.3 0.39 11.0 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY70699.1 - 2.3e-05 23.5 0.0 0.048 12.6 0.0 3.4 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KEY70699.1 - 0.001 17.7 0.3 0.29 9.6 0.1 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain RNA_pol_A_bac PF01000.26 KEY70700.1 - 2e-32 111.8 0.0 3.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEY70700.1 - 3.1e-18 64.9 0.0 4.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 KEY70701.1 - 6.8e-43 144.5 0.0 1.1e-16 60.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 KEY70702.1 - 7.1e-46 156.7 1.1 4.3e-24 85.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KEY70702.1 - 1.1e-26 93.0 0.0 3.8e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.12 KEY70703.1 - 7.2e-52 175.8 0.0 8.5e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.9 KEY70704.1 - 7.6e-25 88.4 0.2 1.4e-24 87.6 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) LPD11 PF18824.1 KEY70704.1 - 0.083 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 Neugrin PF06413.11 KEY70705.1 - 1.1e-08 35.4 0.3 1.1e-08 35.4 0.3 2.0 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KEY70705.1 - 3.2e-06 27.4 1.6 3.2e-06 27.4 1.6 1.8 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Skp1 PF01466.19 KEY70705.1 - 0.0029 17.7 0.5 0.0061 16.6 0.5 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PrmC_N PF17827.1 KEY70705.1 - 0.1 13.2 0.5 0.26 11.9 0.5 1.7 1 0 0 1 1 1 0 PrmC N-terminal domain adh_short PF00106.25 KEY70706.1 - 9.9e-39 132.8 0.4 1.4e-38 132.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70706.1 - 5.3e-32 111.2 0.2 7.3e-32 110.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY70706.1 - 3.5e-11 43.3 2.2 8.8e-10 38.8 2.1 2.5 1 1 1 2 2 2 1 KR domain Pkinase PF00069.25 KEY70707.1 - 7.3e-10 38.7 0.0 0.00024 20.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70707.1 - 0.0064 15.8 0.0 0.061 12.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 KEY70708.1 - 2.1e-96 322.9 0.3 3.5e-96 322.2 0.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Arginase PF00491.21 KEY70708.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Arginase family TRF PF08558.10 KEY70709.1 - 2.7e-15 56.6 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KEY70709.1 - 2.7e-06 27.4 0.1 9.4e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ant_C PF05586.11 KEY70709.1 - 0.032 14.8 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 Anthrax receptor C-terminus region Myb_DNA-bind_6 PF13921.6 KEY70709.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-U PF13097.6 KEY70709.1 - 0.88 9.5 4.0 0.49 10.3 0.9 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit bZIP_1 PF00170.21 KEY70710.1 - 3e-05 24.0 15.0 0.099 12.8 1.7 4.6 2 1 2 4 4 4 2 bZIP transcription factor DUF812 PF05667.11 KEY70710.1 - 0.00031 19.8 9.9 0.00037 19.5 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HOOK PF05622.12 KEY70710.1 - 0.00031 19.0 15.3 0.0006 18.1 15.3 1.3 1 1 0 1 1 1 1 HOOK protein Apolipoprotein PF01442.18 KEY70710.1 - 0.0005 20.0 9.1 0.00086 19.2 9.1 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 KEY70710.1 - 0.0011 19.5 16.6 0.0022 18.5 8.3 2.3 1 1 1 2 2 2 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KEY70710.1 - 0.0038 17.4 12.6 0.038 14.2 5.6 3.1 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 KEY70710.1 - 0.0047 17.0 13.7 0.046 13.8 4.1 3.5 1 1 1 2 2 2 1 TolA binding protein trimerisation Cnn_1N PF07989.11 KEY70710.1 - 0.0052 16.9 3.8 0.0052 16.9 3.8 3.1 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 KEY70710.1 - 0.0054 16.8 5.6 0.0054 16.8 5.6 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.12 KEY70710.1 - 0.0065 16.6 1.0 0.018 15.1 0.4 2.1 1 1 0 1 1 1 1 MbeD/MobD like SHE3 PF17078.5 KEY70710.1 - 0.011 15.5 15.4 0.11 12.2 9.1 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 KEY70710.1 - 0.012 16.3 12.5 0.39 11.4 1.8 3.5 1 1 3 4 4 4 0 Initiation control protein YabA SPAM PF02090.15 KEY70710.1 - 0.013 15.3 2.6 0.013 15.3 2.6 2.2 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein PspA_IM30 PF04012.12 KEY70710.1 - 0.029 13.9 4.9 0.014 15.0 2.8 1.6 1 1 0 1 1 1 0 PspA/IM30 family DUF4407 PF14362.6 KEY70710.1 - 0.033 13.5 5.3 0.12 11.7 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 KEY70710.1 - 0.043 14.2 9.5 1 9.8 1.9 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FtsL PF04999.13 KEY70710.1 - 0.091 12.8 0.7 0.41 10.7 0.7 2.1 1 0 0 1 1 1 0 Cell division protein FtsL DUF1664 PF07889.12 KEY70710.1 - 0.1 12.7 2.1 2 8.5 0.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3800 PF12686.7 KEY70710.1 - 0.11 13.1 1.6 0.22 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) FlaC_arch PF05377.11 KEY70710.1 - 0.13 12.7 3.1 2.7 8.4 0.1 3.2 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 KEY70710.1 - 0.13 10.2 6.0 1.6 6.6 0.4 2.0 1 1 1 2 2 2 0 Prominin Cep57_CLD_2 PF14197.6 KEY70710.1 - 0.13 12.4 17.4 2.9 8.0 0.4 5.0 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 Codanin-1_C PF15296.6 KEY70710.1 - 0.14 12.3 2.7 0.082 13.0 0.4 1.8 2 0 0 2 2 2 0 Codanin-1 C-terminus ADIP PF11559.8 KEY70710.1 - 0.14 12.3 12.6 0.46 10.5 4.1 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc29 PF17082.5 KEY70710.1 - 0.15 11.9 11.0 0.26 11.1 0.9 2.8 2 1 1 3 3 3 0 Spindle Pole Component 29 Fib_alpha PF08702.10 KEY70710.1 - 0.17 12.1 6.8 0.21 11.8 0.9 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 KEY70710.1 - 0.2 12.1 19.9 0.53 10.8 2.6 4.0 1 1 2 3 3 3 0 Cell division protein ZapB DUF2205 PF10224.9 KEY70710.1 - 0.31 11.0 8.5 7.3 6.7 0.0 3.0 2 1 0 3 3 3 0 Short coiled-coil protein Ax_dynein_light PF10211.9 KEY70710.1 - 0.51 10.3 11.8 2.2 8.2 3.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain DivIC PF04977.15 KEY70710.1 - 0.51 10.1 16.1 4.5 7.1 0.2 4.1 1 1 2 3 3 3 0 Septum formation initiator Taxilin PF09728.9 KEY70710.1 - 0.76 8.9 15.3 0.055 12.6 8.0 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Herpes_BLRF2 PF05812.12 KEY70710.1 - 0.84 9.8 6.3 0.76 9.9 2.7 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Spherulin4 PF12138.8 KEY70710.1 - 0.87 9.2 3.1 1.7 8.2 0.6 2.1 2 0 0 2 2 2 0 Spherulation-specific family 4 MRP-S33 PF08293.11 KEY70710.1 - 0.91 9.8 5.0 0.99 9.7 2.6 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit S27 CCDC-167 PF15188.6 KEY70710.1 - 1.2 9.5 10.3 0.54 10.6 2.1 3.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 OmpH PF03938.14 KEY70710.1 - 1.3 9.4 9.5 0.084 13.2 1.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.15 KEY70710.1 - 1.9 8.6 14.3 3.5 7.8 1.1 4.5 3 1 1 4 4 4 0 Basic region leucine zipper HsdM_N PF12161.8 KEY70710.1 - 2 9.0 6.5 1.4 9.6 2.4 2.2 1 1 0 2 2 2 0 HsdM N-terminal domain UPF0242 PF06785.11 KEY70710.1 - 2.1 8.4 16.3 18 5.4 16.2 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus STAT_alpha PF01017.20 KEY70710.1 - 2.4 8.0 10.9 5.9 6.8 4.9 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain TMPIT PF07851.13 KEY70710.1 - 3.3 6.9 8.8 5.5 6.1 2.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF1640 PF07798.11 KEY70710.1 - 3.4 7.7 10.1 5.6 7.0 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) MADF_DNA_bdg PF10545.9 KEY70710.1 - 3.5 8.0 10.3 1.8 8.9 4.9 2.8 2 1 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BST2 PF16716.5 KEY70710.1 - 7.6 7.2 12.0 8.6 7.0 0.1 3.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 SOGA PF11365.8 KEY70710.1 - 9.4 7.4 12.3 1.7 9.8 5.2 2.5 2 2 1 3 3 3 0 Protein SOGA Glyco_hydro_35 PF01301.19 KEY70713.1 - 1.7e-61 208.6 1.0 8.3e-61 206.3 1.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KEY70713.1 - 2.7e-48 163.3 0.2 4.5e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KEY70713.1 - 1e-43 149.3 0.8 2.4e-43 148.1 0.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KEY70713.1 - 3.9e-19 68.0 0.1 1.4e-18 66.2 0.1 2.0 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Fungal_trans PF04082.18 KEY70714.1 - 5.2e-09 35.5 0.1 1.4e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70714.1 - 5.2e-06 26.5 16.9 8.8e-06 25.8 16.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEY70715.1 - 9.4e-69 232.4 22.3 1.2e-68 232.1 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY70715.1 - 1.4e-20 73.5 17.1 1.4e-20 73.5 17.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY70715.1 - 0.0016 17.0 1.2 0.0016 17.0 1.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_88 PF07470.13 KEY70716.1 - 1.2e-13 50.9 0.4 2e-13 50.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Alginate_lyase PF05426.12 KEY70717.1 - 7.1e-05 22.5 0.3 0.00011 21.8 0.3 1.3 1 0 0 1 1 1 1 Alginate lyase DUF2461 PF09365.10 KEY70718.1 - 8.7e-08 32.4 0.0 9.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Exo_endo_phos PF03372.23 KEY70719.1 - 2.1e-09 37.2 0.3 4.2e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HSP70 PF00012.20 KEY70720.1 - 2.5e-265 881.3 12.8 2.8e-265 881.2 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY70720.1 - 4.2e-19 68.5 1.4 1.7e-17 63.2 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KEY70720.1 - 0.0074 16.7 6.2 0.23 11.9 0.1 3.3 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KEY70720.1 - 0.027 13.7 0.2 0.69 9.1 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 KEY70720.1 - 0.033 13.2 0.2 0.32 9.9 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 KEY70720.1 - 0.035 13.6 0.2 0.8 9.1 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family HOIP-UBA PF16678.5 KEY70720.1 - 0.11 12.6 0.6 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 HOIP UBA domain pair GTP_EFTU PF00009.27 KEY70721.1 - 4.6e-47 160.1 0.0 2.2e-46 157.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KEY70721.1 - 6.5e-25 87.2 3.3 1.2e-24 86.4 3.3 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KEY70721.1 - 3e-10 40.4 0.1 1.3e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KEY70721.1 - 6.9e-07 29.4 0.0 9.3e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KEY70721.1 - 1.2e-06 28.8 0.1 4.3e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KEY70721.1 - 0.024 14.9 0.0 5.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KEY70721.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin Cpn60_TCP1 PF00118.24 KEY70722.1 - 1.3e-159 532.0 5.7 1.6e-159 531.7 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NotI PF12183.8 KEY70722.1 - 0.19 11.0 0.9 4.2 6.6 0.1 2.7 3 0 0 3 3 3 0 Restriction endonuclease NotI RTA1 PF04479.13 KEY70723.1 - 1.4e-46 158.8 11.1 5.3e-31 107.8 3.6 2.1 2 0 0 2 2 2 2 RTA1 like protein Phage_holin_3_6 PF07332.11 KEY70723.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III zf-CHY PF05495.12 KEY70724.1 - 7.7e-12 45.5 10.4 7.7e-12 45.5 10.4 3.4 2 1 0 2 2 2 1 CHY zinc finger RWD PF05773.22 KEY70724.1 - 0.00066 19.9 0.2 0.0022 18.2 0.0 1.9 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.9 KEY70724.1 - 0.049 13.1 0.1 0.049 13.1 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_15 PF17032.5 KEY70724.1 - 0.79 10.5 21.0 0.65 10.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon family DUF3295 PF11702.8 KEY70727.1 - 3.4e-142 475.3 31.7 7.6e-142 474.2 31.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KEY70727.1 - 1.2e-12 47.4 1.4 2.6e-12 46.4 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AMP-binding PF00501.28 KEY70729.1 - 7e-85 285.2 0.0 1e-84 284.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY70729.1 - 0.0038 18.2 0.1 0.012 16.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UCH PF00443.29 KEY70730.1 - 1.4e-35 123.1 0.8 2.1e-35 122.5 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY70730.1 - 7.9e-15 55.3 3.2 1.8e-14 54.1 3.2 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KEY70730.1 - 3.4e-10 40.4 0.0 8.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 KEY70730.1 - 0.0023 18.1 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain VHS PF00790.19 KEY70731.1 - 1.1e-40 138.7 3.2 2.5e-40 137.6 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KEY70731.1 - 1.2e-14 54.2 4.4 2e-14 53.5 4.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KEY70731.1 - 1.7e-05 24.4 16.9 0.0025 17.6 1.5 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KEY70731.1 - 6.8e-05 23.1 1.1 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 KEY70731.1 - 0.15 12.3 2.0 0.32 11.2 2.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 KEY70731.1 - 0.44 10.5 7.1 0.81 9.6 7.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_2 PF12797.7 KEY70731.1 - 1.9 8.7 8.3 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M4_C PF02868.15 KEY70732.1 - 2.6e-31 108.8 0.0 6.7e-31 107.4 0.0 1.6 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KEY70732.1 - 7.1e-29 101.2 0.2 1e-28 100.7 0.2 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain DUF4649 PF15507.6 KEY70732.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Glyco_hydro_16 PF00722.21 KEY70733.1 - 7.2e-43 146.1 0.8 1.3e-42 145.3 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF908 PF06012.12 KEY70733.1 - 2.2 7.6 6.4 2.9 7.2 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Apt1 PF10351.9 KEY70733.1 - 5.2 5.8 6.0 6.8 5.4 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mucin PF01456.17 KEY70733.1 - 8.7 6.3 25.1 20 5.2 25.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF572 PF04502.13 KEY70734.1 - 2.9e-66 224.4 0.0 3.8e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SIR2 PF02146.17 KEY70734.1 - 2.5e-33 115.5 0.0 6.1e-33 114.2 0.0 1.7 1 1 0 1 1 1 1 Sir2 family DNA_ligase_ZBD PF03119.16 KEY70734.1 - 0.035 14.1 1.7 0.62 10.1 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain KELK PF15796.5 KEY70734.1 - 1 9.9 4.3 2.4 8.7 4.2 1.6 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FlgN PF05130.12 KEY70734.1 - 2.3 8.7 4.0 1.6 9.3 2.1 1.6 2 0 0 2 2 2 0 FlgN protein UQ_con PF00179.26 KEY70736.1 - 7.8e-36 122.8 0.0 1.1e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 KEY70737.1 - 4.4e-107 357.3 0.8 5.4e-107 357.0 0.8 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KEY70737.1 - 2e-09 37.3 0.1 3.4e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KEY70737.1 - 0.071 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 KEY70738.1 - 2.4e-26 92.0 0.0 3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KEY70738.1 - 0.0021 18.2 0.0 0.0025 18.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lyase_aromatic PF00221.19 KEY70739.1 - 3.5e-145 484.2 7.4 4.6e-145 483.8 7.4 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Dfp1_Him1_M PF08630.10 KEY70740.1 - 1.4e-41 141.7 0.1 1.4e-41 141.7 0.1 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KEY70740.1 - 3.4e-20 71.9 0.4 3.4e-20 71.9 0.4 1.8 2 0 0 2 2 2 1 DBF zinc finger NTPase_P4 PF11602.8 KEY70740.1 - 0.094 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Peptidase_M24 PF00557.24 KEY70741.1 - 1.2e-52 178.6 0.0 1.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEY70741.1 - 3e-32 110.9 0.0 4.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NTP_transferase PF00483.23 KEY70742.1 - 6.3e-53 179.9 0.0 1.4e-52 178.8 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KEY70742.1 - 3.3e-18 64.6 16.6 2.3e-11 42.9 3.7 4.0 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KEY70742.1 - 5e-10 40.0 0.0 6.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KEY70742.1 - 2.4e-07 30.4 10.4 1.3e-06 28.0 2.3 3.6 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KEY70742.1 - 0.00026 19.3 0.1 0.00069 17.9 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 KEY70742.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase FGGY_C PF02782.16 KEY70743.1 - 1.7e-67 227.0 1.9 2.7e-67 226.4 1.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEY70743.1 - 9.2e-64 215.3 0.0 1.3e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Pex14_N PF04695.13 KEY70744.1 - 0.54 10.9 4.3 4.4 7.9 2.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region His_Phos_1 PF00300.22 KEY70745.1 - 1.1e-21 77.5 1.6 1.7e-21 76.8 0.1 1.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.12 KEY70746.1 - 7.8e-22 77.2 6.1 1.2e-21 76.6 6.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY70746.1 - 3.2e-20 72.4 0.0 5.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY70746.1 - 7.6e-09 36.7 0.0 1.3e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEY70746.1 - 0.0067 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEY70746.1 - 0.0071 15.7 0.2 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEY70746.1 - 0.055 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Sec63 PF02889.16 KEY70747.1 - 5.6e-17 61.8 0.0 6.7e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.6 KEY70747.1 - 0.0055 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KEY70747.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH PF00633.23 KEY70747.1 - 0.086 12.8 0.2 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif CEND1 PF15677.5 KEY70748.1 - 0.056 14.0 0.5 0.056 14.0 0.5 2.7 3 0 0 3 3 3 0 Cell cycle exit and neuronal differentiation protein 1 DUF3649 PF12365.8 KEY70748.1 - 1.7 8.4 3.5 5.2 6.9 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Band_7 PF01145.25 KEY70749.1 - 1.5e-31 109.8 0.4 2.7e-31 108.9 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KEY70749.1 - 2.7e-23 81.8 0.1 1e-22 79.9 0.1 2.1 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KEY70749.1 - 0.048 12.9 0.2 0.071 12.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein UQ_con PF00179.26 KEY70750.1 - 2e-17 63.1 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KEY70750.1 - 0.0029 17.5 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KEY70750.1 - 0.0048 17.2 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Flavoprotein PF02441.19 KEY70752.1 - 2.4e-20 72.9 0.0 4.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DCB PF16213.5 KEY70753.1 - 8.2e-48 162.4 5.3 1.1e-46 158.7 5.1 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KEY70753.1 - 1.8e-41 141.7 3.6 4.1e-40 137.3 0.0 4.3 5 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KEY70753.1 - 1.1e-31 109.8 6.3 3.2e-21 75.2 0.1 3.6 3 1 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KEY70753.1 - 0.0001 22.1 2.6 0.014 15.3 0.0 4.6 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) FtsJ PF01728.19 KEY70754.1 - 4.6e-62 209.2 0.0 6.3e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Acetyltransf_1 PF00583.25 KEY70755.1 - 5e-08 33.2 0.0 6.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY70755.1 - 1e-05 25.8 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY70755.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY70755.1 - 0.00093 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KEY70755.1 - 0.0064 16.6 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4078 PF13300.6 KEY70757.1 - 2.1e-28 98.5 20.8 2.1e-28 98.5 20.8 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) bZIP_1 PF00170.21 KEY70757.1 - 2.6e-05 24.2 6.7 2.6e-05 24.2 6.7 2.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY70757.1 - 8.8e-05 22.5 10.4 8.8e-05 22.5 10.4 3.3 3 0 0 3 3 3 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 KEY70757.1 - 0.067 12.2 0.8 0.13 11.2 0.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein zf-C2HCIx2C PF10782.9 KEY70757.1 - 0.11 12.4 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger Homoserine_dh PF00742.19 KEY70758.1 - 3e-52 177.0 0.0 3.9e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KEY70758.1 - 1.7e-19 70.6 0.0 2.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_4 PF02390.17 KEY70759.1 - 1.1e-52 178.0 0.0 1.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KEY70759.1 - 0.0006 20.5 0.0 0.0015 19.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY70759.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY70759.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY70759.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KEY70759.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KEY70760.1 - 2.9e-25 87.9 0.0 1.1e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY70760.1 - 0.039 13.8 0.0 5.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEY70760.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PEX11 PF05648.14 KEY70761.1 - 9e-65 218.2 0.2 1e-64 218.1 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.20 KEY70762.1 - 3.2e-70 235.5 0.2 4.1e-70 235.1 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CIA30 PF08547.12 KEY70763.1 - 2.4e-34 118.7 0.0 3.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 KEY70764.1 - 0.0005 20.1 7.0 0.00081 19.4 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY70764.1 - 0.013 15.5 7.9 0.013 15.5 7.9 1.5 2 0 0 2 2 2 0 Basic region leucine zipper SPATA3 PF15662.5 KEY70764.1 - 0.032 14.9 3.1 0.032 14.9 3.1 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family IQCJ-SCHIP1 PF15157.6 KEY70764.1 - 0.087 12.7 0.7 0.18 11.7 0.7 1.5 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif MCM_bind PF09739.9 KEY70764.1 - 0.69 8.3 4.4 0.97 7.8 4.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor bZIP_Maf PF03131.17 KEY70764.1 - 4.7 7.8 9.8 6.3 7.4 9.4 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF4568 PF15132.6 KEY70765.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) GST_N PF02798.20 KEY70767.1 - 1.7e-09 37.9 0.0 2.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEY70767.1 - 4.8e-09 36.3 0.0 9.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY70767.1 - 2.3e-07 30.7 0.0 5.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEY70767.1 - 4.2e-07 30.2 0.0 7.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY70767.1 - 2.8e-06 27.6 0.0 5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY70767.1 - 3.7e-06 27.0 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PXA PF02194.15 KEY70768.1 - 1.1e-52 178.7 1.2 4.5e-52 176.7 0.4 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KEY70768.1 - 2.2e-27 95.8 0.4 8.9e-27 93.9 0.1 2.3 2 1 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KEY70768.1 - 8.9e-21 74.0 0.7 3.9e-20 71.9 0.8 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KEY70768.1 - 1.8e-13 50.8 0.8 4e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Phage_holin_3_6 PF07332.11 KEY70768.1 - 0.19 11.7 3.5 0.49 10.5 3.5 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Rcd1 PF04078.13 KEY70769.1 - 1.5e-125 417.7 5.1 1.9e-125 417.4 5.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RskA PF10099.9 KEY70769.1 - 0.00013 22.3 8.4 0.00023 21.5 8.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 KEY70769.1 - 0.00067 19.3 14.1 0.0012 18.5 14.1 1.6 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 KEY70769.1 - 0.0068 16.5 23.2 0.0085 16.1 23.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KEY70769.1 - 0.029 13.3 13.3 0.037 13.0 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PAT1 PF09770.9 KEY70769.1 - 0.23 9.7 18.1 0.29 9.4 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 KEY70769.1 - 0.54 10.6 5.2 0.87 10.0 5.2 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 KEY70769.1 - 0.58 9.1 9.4 0.77 8.7 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.10 KEY70769.1 - 0.68 8.6 24.7 0.87 8.2 24.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 KEY70769.1 - 0.79 9.6 10.7 1.2 9.1 10.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Kei1 PF08552.11 KEY70769.1 - 1.8 8.4 6.8 3.3 7.6 6.8 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.13 KEY70769.1 - 2.3 8.9 14.9 3.9 8.1 14.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_TM PF03929.16 KEY70769.1 - 2.4 7.8 5.4 3.4 7.3 5.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM region API5 PF05918.11 KEY70769.1 - 3.1 6.5 12.6 5.4 5.7 12.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ALMT PF11744.8 KEY70769.1 - 3.8 6.2 7.4 5.7 5.7 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Androgen_recep PF02166.16 KEY70769.1 - 4 6.2 23.9 5.5 5.7 23.9 1.2 1 0 0 1 1 1 0 Androgen receptor UPF0560 PF10577.9 KEY70769.1 - 6.4 5.1 15.0 7.5 4.9 15.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CCDC53 PF10152.9 KEY70769.1 - 9.4 6.6 12.1 21 5.5 12.1 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pkinase PF00069.25 KEY70770.1 - 5.8e-70 235.7 0.0 1.3e-69 234.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY70770.1 - 2.3e-39 135.2 0.0 6.2e-39 133.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KEY70770.1 - 5.1e-20 71.0 0.2 8.6e-20 70.3 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KEY70770.1 - 4.6e-06 25.8 0.0 4.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KEY70770.1 - 2.2e-05 23.9 0.1 5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEY70770.1 - 9.5e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEY70770.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KEY70770.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.2 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 KEY70771.1 - 2.7e-40 136.1 1.3 8.3e-40 134.5 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KEY70771.1 - 1e-05 25.3 3.5 1.1e-05 25.2 1.5 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KEY70771.1 - 0.00094 19.2 3.3 0.0013 18.8 0.4 2.8 2 0 0 2 2 2 1 G-patch domain SGL PF08450.12 KEY70772.1 - 0.0019 17.8 1.6 0.93 9.0 0.3 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 KEY70772.1 - 0.012 14.9 5.9 0.015 14.6 3.9 2.2 2 1 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 KEY70772.1 - 0.071 13.4 0.1 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 Two component regulator propeller WD40 PF00400.32 KEY70773.1 - 7.9e-26 89.8 15.5 3.1e-05 24.7 0.0 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY70773.1 - 2e-12 47.2 4.3 0.00042 20.5 0.0 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KEY70773.1 - 7.6e-05 22.7 8.3 0.033 14.1 0.4 3.7 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KEY70773.1 - 0.0044 16.0 0.2 0.87 8.5 0.0 3.5 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BCS1_N PF08740.11 KEY70777.1 - 1.8e-55 187.8 2.7 1.8e-55 187.8 2.7 2.8 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KEY70777.1 - 2.6e-18 66.7 0.0 2.2e-16 60.5 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY70777.1 - 0.00011 22.6 0.1 0.00039 20.8 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KEY70777.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY70777.1 - 0.012 15.6 0.0 0.043 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEY70777.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KEY70777.1 - 0.77 9.5 0.0 0.77 9.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain HMG_CoA_synt_C PF08540.10 KEY70778.1 - 8.9e-102 340.5 0.1 1.1e-101 340.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KEY70778.1 - 5.3e-98 326.0 0.6 7.7e-98 325.5 0.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Tic110 PF16940.5 KEY70778.1 - 0.094 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter FAD_binding_4 PF01565.23 KEY70779.1 - 8e-14 51.6 0.1 1.3e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L12 PF00542.19 KEY70779.1 - 0.094 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Abhydrolase_3 PF07859.13 KEY70780.1 - 8.2e-44 150.0 0.0 8.2e-44 150.0 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEY70780.1 - 0.002 17.0 0.0 0.034 13.0 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase Pex14_N PF04695.13 KEY70781.1 - 8.5e-33 114.2 6.6 8.5e-33 114.2 6.6 4.0 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ERM PF00769.19 KEY70781.1 - 0.0017 18.2 6.4 0.0025 17.7 6.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CR6_interact PF10147.9 KEY70781.1 - 0.0023 17.7 0.8 0.0034 17.1 0.8 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 zf-C4H2 PF10146.9 KEY70781.1 - 0.0027 18.1 5.1 0.0027 18.1 5.1 1.7 2 1 0 2 2 1 1 Zinc finger-containing protein Prominin PF05478.11 KEY70781.1 - 0.0029 15.7 1.8 0.0036 15.3 1.8 1.1 1 0 0 1 1 1 1 Prominin DUF3584 PF12128.8 KEY70781.1 - 0.0068 14.0 13.1 0.0089 13.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1043 PF06295.12 KEY70781.1 - 0.01 15.9 4.7 0.019 15.0 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) HLH PF00010.26 KEY70781.1 - 0.011 15.7 0.1 6.3 6.8 0.2 3.0 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain Golgin_A5 PF09787.9 KEY70781.1 - 0.021 14.3 11.6 0.034 13.6 11.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KEY70781.1 - 0.022 13.7 8.8 0.035 13.0 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HAP1_N PF04849.13 KEY70781.1 - 0.024 13.8 7.9 0.036 13.3 7.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HMMR_N PF15905.5 KEY70781.1 - 0.029 13.8 11.3 0.043 13.3 11.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 KEY70781.1 - 0.034 14.2 3.4 3 7.9 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF1-HH PF16275.5 KEY70781.1 - 0.036 14.4 0.7 0.084 13.2 0.3 1.8 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain TMPIT PF07851.13 KEY70781.1 - 0.062 12.5 3.6 0.1 11.9 3.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein HsbA PF12296.8 KEY70781.1 - 0.068 13.6 0.3 0.14 12.6 0.3 1.6 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF848 PF05852.11 KEY70781.1 - 0.079 13.1 7.1 0.13 12.4 7.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) LMBR1 PF04791.16 KEY70781.1 - 0.087 11.7 0.3 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSD3 PF15244.6 KEY70781.1 - 0.1 12.1 3.7 0.18 11.3 3.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Csm1_N PF18504.1 KEY70781.1 - 0.18 12.2 11.0 0.19 12.1 6.5 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FH2 PF02181.23 KEY70781.1 - 0.19 10.8 6.7 0.27 10.3 6.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain BshC PF10079.9 KEY70781.1 - 0.21 10.3 2.7 0.3 9.8 2.7 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC tRNA-synt_His PF13393.6 KEY70781.1 - 0.23 10.7 2.0 0.75 9.0 0.0 2.0 1 1 2 3 3 3 0 Histidyl-tRNA synthetase ISG65-75 PF11727.8 KEY70781.1 - 0.24 10.6 4.5 0.38 9.9 4.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein SMBP PF16785.5 KEY70781.1 - 0.29 11.4 2.3 2.8 8.2 2.3 2.3 1 1 0 1 1 1 0 Small metal-binding protein V-SNARE PF05008.15 KEY70781.1 - 0.34 11.3 10.0 18 5.8 3.2 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2937 PF11157.8 KEY70781.1 - 0.35 10.6 1.4 0.6 9.8 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) CdvA PF18822.1 KEY70781.1 - 0.38 10.6 12.8 1.5 8.7 4.9 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FUSC PF04632.12 KEY70781.1 - 0.4 9.1 2.1 0.56 8.7 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KEY70781.1 - 0.45 9.5 5.7 0.66 9.0 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KEY70781.1 - 0.49 9.0 8.6 0.72 8.4 8.6 1.2 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 KEY70781.1 - 0.62 10.2 7.8 0.93 9.6 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KEY70781.1 - 0.62 10.1 6.5 1.3 9.1 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KEY70781.1 - 0.72 10.1 12.4 3.6 7.9 12.4 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 KEY70781.1 - 0.88 10.1 7.4 10 6.7 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF572 PF04502.13 KEY70781.1 - 1.3 8.6 8.0 1.8 8.1 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rootletin PF15035.6 KEY70781.1 - 1.7 8.6 11.4 4.9 7.1 11.5 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion 5_nucleotid PF05761.14 KEY70781.1 - 2.4 7.0 6.0 3.2 6.5 6.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family SlyX PF04102.12 KEY70781.1 - 2.5 8.8 5.3 3.2 8.4 3.2 2.4 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.19 KEY70781.1 - 3.3 5.5 4.3 4.7 5.0 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 KEY70781.1 - 3.5 8.0 15.8 1.8 8.8 5.0 3.4 2 1 2 4 4 3 0 ABC transporter C-terminal domain AAA_lid_9 PF17871.1 KEY70781.1 - 4 7.4 9.9 0.78 9.7 3.1 2.3 1 1 1 2 2 2 0 AAA lid domain Occludin_ELL PF07303.13 KEY70781.1 - 4.2 8.1 6.3 16 6.3 5.8 2.0 1 1 0 1 1 1 0 Occludin homology domain DUF4446 PF14584.6 KEY70781.1 - 5.5 7.0 6.9 1.5 8.8 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) NPV_P10 PF05531.12 KEY70781.1 - 6.6 7.3 6.3 15 6.2 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KEY70781.1 - 6.8 7.4 5.9 28 5.4 5.9 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Spectrin PF00435.21 KEY70781.1 - 7.6 7.1 12.6 13 6.4 4.8 2.6 2 1 1 3 3 2 0 Spectrin repeat TraF_2 PF13729.6 KEY70781.1 - 8.6 5.6 6.2 6.5 6.0 1.5 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF4407 PF14362.6 KEY70781.1 - 9.5 5.5 11.8 14 4.9 11.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KEY70781.1 - 10 6.5 13.3 32 4.9 13.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ndc80_HEC PF03801.13 KEY70782.1 - 1.1e-60 203.7 0.4 2.2e-60 202.7 0.4 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family TPR_MLP1_2 PF07926.12 KEY70782.1 - 0.0042 17.2 13.0 0.0042 17.2 13.0 3.7 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein FliJ PF02050.16 KEY70782.1 - 0.0049 17.1 24.4 0.059 13.6 6.2 3.1 2 1 0 2 2 2 2 Flagellar FliJ protein Spc7 PF08317.11 KEY70782.1 - 0.0052 15.7 10.5 0.0052 15.7 10.5 2.7 3 0 0 3 3 3 2 Spc7 kinetochore protein Ntox28 PF15605.6 KEY70782.1 - 0.16 12.2 11.9 2.7 8.3 1.0 3.7 2 2 1 3 3 3 0 Bacterial toxin 28 Golgin_A5 PF09787.9 KEY70782.1 - 0.21 11.0 38.2 0.42 10.0 12.6 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 RPW8 PF05659.11 KEY70782.1 - 0.43 10.3 13.7 1 9.0 3.3 3.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Filament PF00038.21 KEY70782.1 - 0.73 9.4 38.6 0.64 9.5 13.6 3.4 2 1 1 3 3 3 0 Intermediate filament protein APG6_N PF17675.1 KEY70782.1 - 2 9.0 44.2 1.2 9.7 0.4 4.6 3 1 1 4 4 4 0 Apg6 coiled-coil region Tropomyosin PF00261.20 KEY70782.1 - 4.6 6.5 43.3 0.27 10.5 12.4 3.5 2 1 1 3 3 3 0 Tropomyosin DUF4407 PF14362.6 KEY70782.1 - 7.1 5.9 26.9 2.3 7.5 5.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 KEY70782.1 - 7.7 7.1 23.0 0.21 12.1 6.2 3.6 2 2 1 3 3 3 0 Protein of unknown function DUF16 Glyco_hydro_64 PF16483.5 KEY70783.1 - 1.9e-109 366.4 0.0 2.3e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Lactamase_B_2 PF12706.7 KEY70784.1 - 2.2e-27 95.9 0.0 2.5e-26 92.5 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEY70784.1 - 8.6e-09 35.5 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEY70784.1 - 0.024 14.7 5.3 0.1 12.6 3.2 2.7 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily BRCT PF00533.26 KEY70784.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Glyco_hydro_47 PF01532.20 KEY70786.1 - 1.3e-134 449.5 0.0 1.5e-134 449.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.14 KEY70787.1 - 1.1e-47 160.7 0.1 1.7e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Peptidase_S8 PF00082.22 KEY70789.1 - 1.8e-17 63.6 0.9 1.5e-14 54.0 0.6 2.3 1 1 1 2 2 2 2 Subtilase family Ank_2 PF12796.7 KEY70791.1 - 4.3e-61 203.5 1.0 3.7e-13 49.9 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY70791.1 - 8.3e-57 188.9 6.5 4.3e-15 55.9 0.2 9.0 5 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY70791.1 - 3.1e-44 143.9 9.1 5.9e-05 23.2 0.1 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 KEY70791.1 - 1.4e-40 136.0 12.5 7.6e-07 29.3 0.0 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KEY70791.1 - 1.7e-34 117.4 9.1 6.2e-11 42.3 0.4 8.0 4 3 3 8 8 8 7 Ankyrin repeats (many copies) HlyIII PF03006.20 KEY70792.1 - 9.7e-21 74.5 9.7 1.2e-20 74.2 9.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ank_2 PF12796.7 KEY70793.1 - 3.6e-23 82.0 0.0 1.4e-11 44.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY70793.1 - 3.4e-18 65.5 5.5 2.4e-08 34.1 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY70793.1 - 6.5e-18 64.3 0.3 0.00063 20.1 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KEY70793.1 - 1.1e-17 62.3 0.3 0.00011 22.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KEY70793.1 - 3.5e-14 52.9 3.0 1.4e-08 35.1 0.0 4.2 2 1 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 KEY70793.1 - 1.8e-10 41.0 0.1 5.3e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KEY70793.1 - 2.3e-08 33.6 0.1 5.9e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily KAP_NTPase PF07693.14 KEY70793.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Mg_chelatase PF01078.21 KEY70793.1 - 0.049 13.0 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEY70793.1 - 0.06 13.3 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KEY70793.1 - 0.12 12.7 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.20 KEY70794.1 - 7.7e-46 155.9 3.1 2e-45 154.5 3.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEY70794.1 - 6.5e-23 82.1 0.0 1.2e-22 81.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEY70794.1 - 1.2e-05 25.6 0.1 3.9e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KEY70794.1 - 0.00041 20.2 0.2 0.0011 18.7 0.2 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase MauE PF07291.11 KEY70794.1 - 0.092 12.5 6.8 0.054 13.3 1.2 2.6 2 0 0 2 2 2 0 Methylamine utilisation protein MauE TPR_12 PF13424.6 KEY70795.1 - 9.7e-05 22.6 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY70795.1 - 0.0059 16.4 0.0 0.0079 16.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY70795.1 - 0.013 15.4 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY70795.1 - 0.019 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY70795.1 - 0.024 14.9 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70795.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY70795.1 - 0.11 13.1 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEY70795.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.0 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal PNP_UDP_1 PF01048.20 KEY70796.1 - 0.011 15.0 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily Kelch_3 PF13415.6 KEY70796.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 Galactose oxidase, central domain DUF1908 PF08926.11 KEY70796.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) HALZ PF02183.18 KEY70797.1 - 0.00038 20.6 2.4 0.0056 16.9 0.3 4.8 6 1 1 7 7 7 2 Homeobox associated leucine zipper Prefoldin_3 PF13758.6 KEY70797.1 - 0.055 13.5 7.3 0.53 10.4 4.8 2.7 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 KEY70797.1 - 0.071 12.5 14.7 0.055 12.8 13.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KEY70797.1 - 0.2 11.5 8.2 4.6 7.0 8.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KEY70797.1 - 0.38 9.6 19.7 0.15 10.9 16.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 KEY70797.1 - 0.41 9.5 10.0 0.5 9.2 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Occludin_ELL PF07303.13 KEY70797.1 - 1.1 10.0 9.6 4.9 7.9 1.4 2.5 1 1 1 2 2 2 0 Occludin homology domain YabA PF06156.13 KEY70797.1 - 2.7 8.7 17.2 0.34 11.6 0.9 3.3 1 1 2 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KEY70797.1 - 5.1 7.1 8.2 1.4 9.0 0.9 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 KEY70797.1 - 6.1 7.5 10.2 3.2 8.4 3.3 3.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_106 PF17132.4 KEY70801.1 - 4.6e-07 28.5 2.8 5.7e-05 21.6 0.3 2.9 2 1 1 3 3 3 3 alpha-L-rhamnosidase Beta_helix PF13229.6 KEY70803.1 - 0.00089 19.1 0.7 0.001 18.9 0.7 1.1 1 0 0 1 1 1 1 Right handed beta helix region Epimerase PF01370.21 KEY70804.1 - 3.6e-12 46.3 0.0 1.4e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY70804.1 - 3.6e-11 43.3 0.0 6.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY70804.1 - 9.1e-10 38.0 0.0 1.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEY70804.1 - 6e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY70804.1 - 5.6e-06 26.0 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY70804.1 - 8.8e-05 21.8 0.2 0.00027 20.2 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KEY70804.1 - 0.00027 20.2 0.1 0.022 13.9 0.0 2.7 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.25 KEY70804.1 - 0.0026 17.2 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Glyoxalase PF00903.25 KEY70805.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3435 PF11917.8 KEY70806.1 - 0.00045 19.3 0.1 0.025 13.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) DUF3632 PF12311.8 KEY70808.1 - 2.9e-27 96.2 3.1 3.8e-27 95.8 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Peptidase_M36 PF02128.15 KEY70810.1 - 0.00058 19.1 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Trypsin PF00089.26 KEY70811.1 - 1.1e-36 126.8 0.3 1.3e-36 126.5 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KEY70811.1 - 3.7e-05 24.6 0.8 6.1e-05 24.0 0.8 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.16 KEY70812.1 - 2.1e-12 46.6 28.4 9.2e-12 44.5 7.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY70812.1 - 0.00047 19.1 0.2 0.00047 19.1 0.2 2.0 2 1 0 2 2 2 1 MFS_1 like family 60KD_IMP PF02096.20 KEY70812.1 - 5.2 6.9 9.9 0.2 11.6 3.2 2.1 2 1 0 2 2 2 0 60Kd inner membrane protein Peptidase_M20 PF01546.28 KEY70814.1 - 5.6e-06 26.2 0.1 8.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY70814.1 - 7.2e-05 22.7 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ICL PF00463.21 KEY70815.1 - 2.5e-42 145.1 0.2 3.8e-23 81.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 KEY70815.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HLH PF00010.26 KEY70816.1 - 3.6e-09 36.4 0.8 8e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PHO4 PF01384.20 KEY70817.1 - 2.4e-109 365.5 10.2 2.8e-109 365.3 10.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Mem_trans PF03547.18 KEY70819.1 - 0.0034 15.9 0.2 0.0051 15.3 0.2 1.2 1 0 0 1 1 1 1 Membrane transport protein bZIP_1 PF00170.21 KEY70820.1 - 0.73 10.0 7.9 1.8 8.8 7.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor Metal_resist PF13801.6 KEY70820.1 - 1.2 9.3 11.7 0.11 12.7 3.0 2.3 2 0 0 2 2 2 0 Heavy-metal resistance SBF PF01758.16 KEY70821.1 - 7.8e-51 172.5 10.6 7.8e-51 172.5 10.6 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF2897 PF11446.8 KEY70821.1 - 1.5 8.8 5.6 4.6 7.2 5.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Rhodanese PF00581.20 KEY70822.1 - 1.1e-05 25.9 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain FSH1 PF03959.13 KEY70823.1 - 1.4e-27 96.8 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KEY70823.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_47 PF01532.20 KEY70824.1 - 1.5e-167 558.2 0.0 1.7e-167 558.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GMC_oxred_C PF05199.13 KEY70825.1 - 2.1e-34 119.1 0.0 3.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEY70825.1 - 1.7e-24 86.8 0.0 3.4e-22 79.2 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY70825.1 - 8.7e-05 22.7 0.1 0.00027 21.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY70825.1 - 0.0025 16.9 0.0 0.0057 15.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY70825.1 - 0.025 13.8 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY70825.1 - 0.031 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KEY70825.1 - 0.06 12.9 2.3 6.1 6.3 1.4 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY70825.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KEY70825.1 - 0.32 10.2 0.3 8.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S8 PF00082.22 KEY70826.1 - 5.1e-45 154.0 2.2 8.2e-45 153.3 2.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEY70826.1 - 7.8e-09 36.2 0.0 1.7e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain DUF4232 PF14016.6 KEY70826.1 - 0.0022 18.1 0.1 0.0085 16.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) PA PF02225.22 KEY70826.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 PA domain SDA1 PF05285.12 KEY70827.1 - 0.0046 16.4 20.6 0.0066 15.9 20.6 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KEY70827.1 - 5 5.2 27.6 7 4.7 27.6 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KEY70827.1 - 9.2 4.6 21.0 13 4.0 21.0 1.1 1 0 0 1 1 1 0 Mpp10 protein adh_short PF00106.25 KEY70828.1 - 1.1e-46 158.8 4.8 1.4e-46 158.4 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70828.1 - 1.7e-39 135.8 2.0 2e-39 135.6 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY70828.1 - 1.8e-11 44.3 1.8 2.4e-11 43.9 1.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY70828.1 - 3.9e-06 26.9 0.4 5.2e-06 26.5 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY70828.1 - 0.00011 21.8 0.2 0.00021 20.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY70828.1 - 0.0022 17.2 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KEY70828.1 - 0.0026 18.0 0.5 0.0096 16.1 0.2 2.0 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KEY70828.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KEY70828.1 - 0.0061 15.9 0.1 0.0097 15.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KEY70828.1 - 0.0096 16.0 0.2 0.019 15.0 0.2 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KEY70828.1 - 0.012 14.9 0.1 0.06 12.7 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 KEY70828.1 - 0.015 15.9 0.2 0.035 14.7 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KEY70828.1 - 0.016 14.2 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEY70828.1 - 0.026 14.4 1.3 0.16 11.8 2.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding DapB_N PF01113.20 KEY70828.1 - 0.026 14.6 1.2 0.19 11.9 1.0 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KEY70828.1 - 0.041 13.0 0.1 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 KEY70828.1 - 0.046 13.5 0.4 0.096 12.5 0.4 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 KEY70828.1 - 0.13 12.7 0.2 0.21 12.0 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding CLCA PF08434.11 KEY70828.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal HET PF06985.11 KEY70830.1 - 1.6e-23 83.7 0.0 4.3e-23 82.3 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY70831.1 - 1.3e-30 106.7 0.3 2.1e-29 102.8 0.3 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RuvB_N PF05496.12 KEY70831.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Abhydrolase_6 PF12697.7 KEY70832.1 - 5.4e-19 69.7 0.1 6.3e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY70832.1 - 0.00017 21.3 0.2 0.065 12.9 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY70832.1 - 0.016 14.5 0.7 0.37 10.0 0.3 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short PF00106.25 KEY70834.1 - 1.7e-25 89.6 0.0 5.7e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY70834.1 - 1.7e-12 47.4 0.0 1.2e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY70834.1 - 2.2e-07 30.9 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY70834.1 - 9e-07 28.6 0.1 2.5e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY70834.1 - 8.1e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY70834.1 - 0.0018 17.4 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEY70834.1 - 0.0023 18.2 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF4957 PF16318.5 KEY70834.1 - 0.003 17.5 0.0 0.0076 16.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4957) Shikimate_DH PF01488.20 KEY70834.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KEY70834.1 - 0.053 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3801 PF12687.7 KEY70834.1 - 0.19 11.8 0.3 5.7 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) Arginosuc_synth PF00764.19 KEY70835.1 - 9.4e-31 107.4 0.1 8.4e-15 54.9 0.0 3.0 2 1 1 3 3 3 3 Arginosuccinate synthase MFS_1 PF07690.16 KEY70836.1 - 5.3e-42 144.0 24.6 5.3e-42 144.0 24.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KEY70836.1 - 8.7 6.1 18.0 0.28 11.0 3.2 3.1 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1996 PF09362.10 KEY70837.1 - 5.8e-82 275.2 0.2 7.4e-82 274.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 KEY70837.1 - 4.6e-14 52.1 7.9 4.6e-14 52.1 7.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Mpv17_PMP22 PF04117.12 KEY70838.1 - 3e-14 53.0 1.1 5.4e-14 52.2 1.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family 3Beta_HSD PF01073.19 KEY70839.1 - 6.4e-21 74.6 0.0 5.6e-20 71.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY70839.1 - 4.8e-10 39.3 0.0 1.2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY70839.1 - 2.9e-07 29.9 0.0 0.00013 21.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEY70839.1 - 6.1e-05 23.0 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY70839.1 - 9.8e-05 22.3 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY70839.1 - 0.00015 21.0 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEY70839.1 - 0.0013 18.2 0.0 0.0049 16.3 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KEY70839.1 - 0.099 12.1 0.0 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Yip1 PF04893.17 KEY70840.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain VSP PF03302.13 KEY70840.1 - 0.075 11.9 0.4 0.1 11.5 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FTR1 PF03239.14 KEY70840.1 - 0.17 11.0 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family AAA_9 PF12781.7 KEY70842.1 - 0.12 11.5 0.7 0.21 10.7 0.7 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region Mem_trans PF03547.18 KEY70842.1 - 1.1 7.5 2.3 1.8 6.9 2.3 1.3 1 0 0 1 1 1 0 Membrane transport protein SOG2 PF10428.9 KEY70842.1 - 2.7 7.1 31.5 2.7 7.1 12.2 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein TRAP_alpha PF03896.16 KEY70842.1 - 3.1 6.9 10.5 8.8 5.4 9.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit HET PF06985.11 KEY70843.1 - 8.3e-37 126.8 0.1 1.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PGAP1 PF07819.13 KEY70844.1 - 3.6e-93 311.5 0.0 5.4e-93 311.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEY70844.1 - 1.5e-05 25.7 1.9 1.8e-05 25.5 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY70844.1 - 0.0022 17.3 0.0 0.006 15.9 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY70844.1 - 0.0048 16.6 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KEY70844.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KEY70844.1 - 0.032 13.7 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KEY70844.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KEY70844.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.20 KEY70844.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 2 0 0 2 2 2 0 Putative esterase PRP38_assoc PF12871.7 KEY70844.1 - 5.9 7.6 7.0 11 6.7 7.0 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MFS_1 PF07690.16 KEY70845.1 - 7.9e-16 57.9 39.3 3.5e-10 39.3 25.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEY70845.1 - 4.9e-13 49.1 3.4 4.9e-13 49.1 3.4 2.3 2 0 0 2 2 2 1 Nodulin-like FeS PF04060.13 KEY70845.1 - 0.24 11.1 0.7 0.55 9.9 0.7 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster DUF4229 PF14012.6 KEY70845.1 - 4 7.6 0.0 4 7.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Serinc PF03348.15 KEY70846.1 - 8.4e-152 506.0 8.3 1e-151 505.8 8.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.20 KEY70847.1 - 2.3e-138 460.9 0.0 2.7e-138 460.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEY70847.1 - 1.6e-07 30.8 0.0 2.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEY70847.1 - 1.1e-06 27.8 0.0 3.2e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEY70847.1 - 2e-05 24.1 0.0 6.7e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KEY70847.1 - 5.3e-05 21.9 0.1 0.00015 20.4 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KEY70847.1 - 0.00043 19.2 0.1 0.0012 17.8 0.0 1.6 1 1 1 2 2 2 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KEY70847.1 - 0.046 13.0 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase AAA PF00004.29 KEY70848.1 - 3.6e-38 131.0 0.0 5.9e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY70848.1 - 3e-08 33.3 0.0 6.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEY70848.1 - 3e-06 27.7 0.2 0.00031 21.2 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY70848.1 - 5.9e-06 26.6 0.4 0.0024 18.1 0.0 3.6 2 1 2 4 4 4 1 AAA domain AAA_14 PF13173.6 KEY70848.1 - 6.1e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY70848.1 - 1.2e-05 25.3 0.5 9.6e-05 22.4 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEY70848.1 - 1.5e-05 24.8 0.0 4.9e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEY70848.1 - 7.5e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEY70848.1 - 0.00075 20.0 0.1 0.004 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEY70848.1 - 0.00085 18.8 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KEY70848.1 - 0.00089 18.7 0.1 1.9 7.9 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein RNA_helicase PF00910.22 KEY70848.1 - 0.0013 19.1 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KEY70848.1 - 0.0014 18.8 0.6 0.0042 17.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEY70848.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEY70848.1 - 0.0046 17.2 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 KEY70848.1 - 0.0066 16.4 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 KEY70848.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF815 PF05673.13 KEY70848.1 - 0.0077 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEY70848.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KEY70848.1 - 0.0094 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 KEY70848.1 - 0.014 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEY70848.1 - 0.016 14.8 1.8 0.028 14.0 0.1 2.2 3 0 0 3 3 2 0 AAA domain Guanylate_kin PF00625.21 KEY70848.1 - 0.017 14.8 0.0 0.59 9.8 0.0 2.8 2 1 1 3 3 3 0 Guanylate kinase AAA_7 PF12775.7 KEY70848.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEY70848.1 - 0.022 15.3 0.0 0.071 13.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KEY70848.1 - 0.026 14.4 0.0 0.22 11.4 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KEY70848.1 - 0.042 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KEY70848.1 - 0.057 12.7 0.4 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KEY70848.1 - 0.059 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KEY70848.1 - 0.081 12.1 0.2 0.64 9.2 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain Oxidored_nitro PF00148.19 KEY70848.1 - 0.094 11.4 0.0 5.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TIP49 PF06068.13 KEY70848.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SMC_N PF02463.19 KEY70848.1 - 0.13 11.7 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Bac_DnaA PF00308.18 KEY70848.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein TOM6p PF15184.6 KEY70848.1 - 0.18 11.6 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog AAA_17 PF13207.6 KEY70848.1 - 0.25 11.8 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain BLACT_WH PF17778.1 KEY70848.1 - 0.74 9.8 2.1 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Csm1 PF12539.8 KEY70849.1 - 3e-33 114.3 0.1 6.4e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF885 PF05960.11 KEY70849.1 - 0.00018 21.3 2.7 0.00031 20.5 2.7 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) FPP PF05911.11 KEY70849.1 - 0.0015 16.8 5.4 0.0021 16.4 5.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil PspA_IM30 PF04012.12 KEY70849.1 - 0.0034 17.0 12.8 0.0034 17.0 12.8 1.7 2 0 0 2 2 2 1 PspA/IM30 family Rootletin PF15035.6 KEY70849.1 - 0.017 15.1 11.4 0.033 14.2 11.4 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 KEY70849.1 - 0.02 15.0 4.4 0.034 14.3 4.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 KEY70849.1 - 0.051 13.3 8.1 0.32 10.7 0.4 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF5094 PF17015.5 KEY70849.1 - 0.051 13.7 0.0 0.051 13.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) Med9 PF07544.13 KEY70849.1 - 0.062 13.4 1.2 0.31 11.2 0.3 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 mCpol PF18182.1 KEY70849.1 - 0.11 12.9 0.5 0.2 12.0 0.5 1.4 1 0 0 1 1 1 0 minimal CRISPR polymerase domain IpaB_EvcA PF03278.13 KEY70849.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 IpaB/EvcA family FlaC_arch PF05377.11 KEY70849.1 - 0.21 12.0 0.7 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KEY70849.1 - 0.34 10.4 13.4 0.012 15.2 7.5 1.5 2 0 0 2 2 2 0 Intermediate filament protein DHR10 PF18595.1 KEY70849.1 - 0.54 10.3 20.4 0.69 10.0 7.2 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 KEY70849.1 - 0.56 9.0 12.7 0.9 8.4 12.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.11 KEY70849.1 - 0.92 7.4 2.2 1.3 6.9 2.2 1.1 1 0 0 1 1 1 0 Prominin HIP1_clath_bdg PF16515.5 KEY70849.1 - 0.99 10.1 13.3 2.6 8.7 10.2 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 KEY70849.1 - 1 9.7 13.0 9.3 6.5 3.5 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 AAA_13 PF13166.6 KEY70849.1 - 1.1 7.8 6.3 1.8 7.1 6.3 1.3 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KEY70849.1 - 5.8 5.9 12.4 0.08 12.0 5.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PigN PF04987.14 KEY70850.1 - 1.9e-159 531.4 33.1 2.5e-159 531.0 33.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KEY70850.1 - 2.8e-09 37.0 3.0 1.2e-06 28.4 1.9 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEY70850.1 - 2.4e-08 33.7 0.6 2.4e-08 33.7 0.6 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KEY70850.1 - 2.6e-05 23.7 0.1 5.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 KEY70851.1 - 2.5e-38 131.7 0.0 4.5e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70851.1 - 0.00071 19.6 1.8 0.0012 18.9 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 KEY70852.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain Arv1 PF04161.13 KEY70853.1 - 4e-61 206.8 4.4 2.1e-58 197.9 4.4 2.1 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KEY70854.1 - 1.7e-24 86.1 1.4 1.9e-24 85.9 1.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H YfhO PF09586.10 KEY70854.1 - 0.039 12.2 0.3 0.042 12.1 0.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2070 PF09843.9 KEY70854.1 - 0.13 10.5 0.1 0.14 10.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TauD PF02668.16 KEY70856.1 - 3.4e-64 217.2 1.0 4.2e-64 216.9 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NAD_binding_2 PF03446.15 KEY70857.1 - 3.9e-28 98.6 0.0 6e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEY70857.1 - 2.4e-09 37.5 0.2 5.2e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KEY70857.1 - 6.5e-08 33.1 0.0 2.8e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEY70857.1 - 3.8e-07 30.2 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEY70857.1 - 0.065 13.1 1.0 0.082 12.8 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NAT PF04768.13 KEY70858.1 - 7.6e-52 175.4 0.0 2e-51 174.0 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase BAR_2 PF10455.9 KEY70859.1 - 7.3e-61 205.8 0.1 1.5e-60 204.8 0.1 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking ETC_C1_NDUFA5 PF04716.14 KEY70859.1 - 1.2e-24 85.9 6.3 4.2e-24 84.1 0.1 2.9 3 0 0 3 3 3 2 ETC complex I subunit conserved region BAR PF03114.18 KEY70859.1 - 7.2e-23 81.5 1.0 5.7e-16 58.9 0.1 2.3 2 0 0 2 2 2 2 BAR domain BAR_3 PF16746.5 KEY70859.1 - 0.00082 19.1 0.6 0.0043 16.8 0.1 2.3 2 0 0 2 2 2 1 BAR domain of APPL family Spc7 PF08317.11 KEY70859.1 - 0.052 12.4 1.1 0.28 10.0 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein STG PF15809.5 KEY70859.1 - 0.09 12.8 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Simian taste bud-specific gene product family RNA_pol_I_TF PF04090.12 KEY70860.1 - 0.016 14.7 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Sigma70_ner PF04546.13 KEY70860.1 - 0.23 11.3 7.3 0.11 12.4 2.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleo_P87 PF07267.11 KEY70860.1 - 0.64 8.8 3.9 0.21 10.4 0.4 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 GEN1_C PF18380.1 KEY70860.1 - 1.2 10.0 3.7 1.1 10.2 0.3 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain WD40 PF00400.32 KEY70861.1 - 1e-14 54.7 18.5 0.00016 22.4 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PAS_3 PF08447.12 KEY70862.1 - 5e-13 49.1 0.0 2.2e-09 37.5 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KEY70862.1 - 2.8e-10 40.4 0.0 4.6e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KEY70862.1 - 2.9e-09 36.9 0.0 2.5e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KEY70862.1 - 6.1e-07 29.6 0.0 1.1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KEY70862.1 - 0.00039 20.7 0.0 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_12 PF18095.1 KEY70862.1 - 0.028 14.1 0.0 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain APH PF01636.23 KEY70863.1 - 7.2e-05 22.8 0.6 0.0001 22.3 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Yip1 PF04893.17 KEY70864.1 - 7.6e-13 48.5 14.5 1.2e-12 47.9 14.5 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KEY70864.1 - 0.016 15.0 6.9 0.027 14.3 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) p53-inducible11 PF14936.6 KEY70864.1 - 0.37 10.8 2.8 0.74 9.8 2.8 1.4 1 1 0 1 1 1 0 Tumour protein p53-inducible protein 11 Ran_BP1 PF00638.18 KEY70865.1 - 1.1e-14 54.7 0.5 6.1e-06 26.5 0.2 2.6 2 1 0 2 2 2 2 RanBP1 domain Glyco_hydro_75 PF07335.11 KEY70865.1 - 0.0047 17.2 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 DEAD PF00270.29 KEY70866.1 - 6e-26 91.3 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KEY70866.1 - 6.2e-22 78.2 0.4 1.8e-21 76.7 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KEY70866.1 - 1.1e-10 41.8 0.0 8.1e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY70866.1 - 3e-07 30.6 0.0 7.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KEY70866.1 - 4.7e-05 23.8 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like Na_Ca_ex PF01699.24 KEY70867.1 - 6.6e-23 81.3 33.9 1e-13 51.5 14.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3185 PF11381.8 KEY70867.1 - 0.00021 21.2 1.5 0.099 12.7 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3185) DUF1298 PF06974.13 KEY70867.1 - 0.019 14.9 0.5 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) DUF4131 PF13567.6 KEY70867.1 - 1.6 8.3 8.6 17 5.0 0.2 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MIF4G PF02854.19 KEY70868.1 - 1.1e-55 188.6 0.0 7.4e-27 94.4 0.0 4.1 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 KEY70868.1 - 3.6e-40 137.8 9.9 3.6e-40 137.8 9.9 2.6 3 0 0 3 3 3 1 Up-frameshift suppressor 2 RseA_C PF03873.13 KEY70868.1 - 0.051 13.8 1.7 0.15 12.3 1.7 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain CBP4 PF07960.11 KEY70868.1 - 0.052 13.4 0.0 0.052 13.4 0.0 2.5 3 0 0 3 3 3 0 CBP4 Chitin_synth_2 PF03142.15 KEY70869.1 - 3.6e-24 85.3 3.9 7.3e-22 77.7 2.1 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEY70869.1 - 5.8e-17 62.3 5.9 5.8e-17 62.3 5.9 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY70869.1 - 3.1e-13 50.2 0.0 6.6e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEY70869.1 - 0.053 13.3 0.1 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.20 KEY70870.1 - 2.3e-164 547.9 2.5 2.3e-164 547.9 2.5 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KEY70870.1 - 3.4e-13 49.1 0.0 3.4e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 KEY70870.1 - 0.002 18.5 2.1 0.83 10.1 0.1 3.4 2 2 0 2 2 2 2 Cell division protein FtsA Apolipoprotein PF01442.18 KEY70870.1 - 0.0033 17.3 12.0 0.0087 16.0 12.0 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain GTP_EFTU PF00009.27 KEY70871.1 - 3.4e-33 114.8 0.0 1.8e-32 112.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KEY70871.1 - 8.6e-19 67.6 0.0 2.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KEY70871.1 - 1.7e-09 37.9 9.3 3.1e-08 33.9 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEY70871.1 - 2.6e-08 33.9 0.3 9.6e-07 28.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KEY70871.1 - 8.9e-07 28.7 1.6 8.9e-07 28.7 1.6 2.5 2 1 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 KEY70871.1 - 0.00013 22.1 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KEY70871.1 - 0.011 15.5 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LtuB PF17455.2 KEY70871.1 - 0.069 13.8 1.7 0.24 12.1 0.3 2.6 2 0 0 2 2 2 0 Late transcription unit B MMS1_N PF10433.9 KEY70872.1 - 9.6e-62 209.2 0.0 1.9e-61 208.2 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 KEY70873.1 - 6.5e-20 71.7 0.0 9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF883 PF05957.13 KEY70873.1 - 0.058 14.0 0.3 0.15 12.7 0.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Vps52 PF04129.12 KEY70874.1 - 2.2e-114 383.0 6.8 5.2e-114 381.8 6.8 1.5 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KEY70874.1 - 0.001 17.6 6.6 0.0057 15.1 6.6 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Exo70 PF03081.15 KEY70874.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit ANTAR PF03861.14 KEY70874.1 - 0.076 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 ANTAR domain Orbi_VP4 PF05059.12 KEY70874.1 - 0.078 11.0 0.2 0.12 10.4 0.2 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Pkip-1 PF06878.11 KEY70874.1 - 0.18 11.9 3.0 0.33 11.1 0.2 2.2 2 0 0 2 2 2 0 Pkip-1 protein eIF-5a PF01287.20 KEY70875.1 - 1.5e-28 98.6 1.5 2.2e-28 98.1 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KEY70875.1 - 0.026 14.5 0.2 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 KEY70876.1 - 0.0011 18.6 0.4 0.0019 17.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkip-1 PF06878.11 KEY70876.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Pkip-1 protein Yip1 PF04893.17 KEY70877.1 - 6.8e-14 52.0 15.3 6.8e-14 52.0 15.3 1.4 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.20 KEY70878.1 - 5.1e-11 43.1 0.0 8.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 KEY70879.1 - 4.7e-50 170.7 0.0 8.1e-50 169.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 BCDHK_Adom3 PF10436.9 KEY70880.1 - 1.3e-42 145.4 0.0 1.9e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEY70880.1 - 8e-10 39.2 0.0 2.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 KEY70880.1 - 5.8e-09 36.5 0.1 1.3e-08 35.3 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 HATPase_c_2 PF13581.6 KEY70880.1 - 0.04 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Chitin_synth_2 PF03142.15 KEY70881.1 - 5.6e-229 761.1 0.1 7.6e-229 760.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KEY70881.1 - 1.9e-15 56.5 2.2 1.3e-14 53.8 2.8 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KEY70881.1 - 2.4e-14 53.7 2.5 5.4e-14 52.6 2.5 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KEY70881.1 - 1.8e-13 50.5 0.3 7.8e-11 42.0 0.0 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KEY70881.1 - 4e-11 43.2 0.0 2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KEY70881.1 - 2.7e-07 29.2 0.0 6.8e-07 27.9 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 KEY70881.1 - 0.0003 20.7 0.0 0.066 13.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEY70881.1 - 0.0019 17.7 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KEY70881.1 - 0.061 13.8 0.2 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2157 PF09925.9 KEY70881.1 - 0.094 12.5 1.2 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Chitin_synth_2 PF03142.15 KEY70882.1 - 8.1e-248 823.3 2.0 1.1e-247 822.9 2.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KEY70882.1 - 3e-75 253.8 0.0 1.8e-74 251.2 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KEY70882.1 - 3.9e-15 55.5 0.1 1.7e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KEY70882.1 - 8.6e-14 51.4 0.2 1.2e-10 41.4 0.0 3.2 3 1 0 3 3 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KEY70882.1 - 1.3e-11 44.8 4.4 1.3e-11 44.8 4.4 2.1 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY70882.1 - 4.1e-08 33.4 0.1 6.1e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEY70882.1 - 3e-06 27.2 0.0 0.0032 17.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_25 PF13481.6 KEY70882.1 - 0.0026 17.4 0.1 0.059 13.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY70882.1 - 0.014 15.8 0.3 0.048 14.0 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KEY70882.1 - 0.021 15.3 0.1 0.068 13.7 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KEY70882.1 - 0.035 13.9 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY70882.1 - 0.045 14.0 0.8 0.17 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KEY70882.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KEY70882.1 - 0.097 13.1 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KEY70882.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KEY70882.1 - 0.11 12.6 1.6 3.5 7.7 0.2 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KEY70882.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Npa1 PF11707.8 KEY70883.1 - 2e-97 326.6 0.0 6.4e-97 325.0 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KEY70883.1 - 5.5e-64 215.5 6.0 9.7e-64 214.7 0.3 3.5 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 CP12 PF02672.15 KEY70883.1 - 4.2 8.2 4.6 3.8 8.3 0.0 3.0 3 0 0 3 3 3 0 CP12 domain His_Phos_2 PF00328.22 KEY70885.1 - 5.3e-56 190.6 0.0 6.1e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.22 KEY70887.1 - 9.8e-43 146.5 0.1 1.3e-29 103.3 0.1 2.7 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.18 KEY70888.1 - 2.6e-07 29.9 0.1 4.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PS-DH PF14765.6 KEY70889.1 - 4.6e-70 236.2 0.0 8.1e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEY70889.1 - 1.8e-56 191.5 0.0 4.2e-56 190.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY70889.1 - 6e-54 182.7 1.0 1.1e-52 178.6 0.1 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEY70889.1 - 1.2e-50 172.9 1.8 1.2e-50 172.8 0.2 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY70889.1 - 4.1e-30 104.2 0.0 9.3e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY70889.1 - 7.3e-16 58.6 10.4 1.5e-10 41.5 0.1 3.5 2 1 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KEY70889.1 - 2.4e-14 53.4 1.3 4.2e-13 49.4 0.3 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY70889.1 - 1.1e-09 38.0 1.2 2.5e-06 27.1 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KEY70889.1 - 1.3e-09 39.2 0.1 1.4e-06 29.4 0.1 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KEY70889.1 - 7.2e-09 36.3 0.1 5.4e-08 33.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KEY70889.1 - 1.4e-07 31.8 0.1 3.7e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KEY70889.1 - 7.2e-06 25.7 6.2 9.4e-06 25.3 0.1 3.8 3 1 1 4 4 4 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KEY70889.1 - 4.1e-05 24.1 0.0 0.0002 21.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY70889.1 - 6.4e-05 22.8 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY70889.1 - 0.00032 20.6 0.0 0.00086 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KEY70889.1 - 0.00043 20.1 0.3 0.0013 18.6 0.0 2.0 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.19 KEY70889.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KEY70889.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 KEY70889.1 - 0.004 16.3 0.0 0.009 15.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KEY70889.1 - 0.0091 15.8 1.0 0.039 13.8 0.2 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KEY70889.1 - 0.039 13.3 1.1 0.059 12.7 0.0 1.8 2 0 0 2 2 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 KEY70890.1 - 5.6e-31 107.7 59.2 7.5e-30 104.0 58.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70890.1 - 1.8e-09 37.0 8.3 1.8e-09 37.0 8.3 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter Inositol_P PF00459.25 KEY70892.1 - 2e-59 201.3 0.2 1.3e-58 198.7 0.2 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family La PF05383.17 KEY70893.1 - 8.6e-18 64.1 0.0 1.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KEY70893.1 - 1.2e-09 37.9 0.2 2e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PLA2_B PF01735.18 KEY70894.1 - 1.4e-27 96.3 0.0 7.1e-27 94.0 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 KEY70894.1 - 0.049 13.8 1.3 6 7.0 0.3 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase Endonuc_Holl PF10107.9 KEY70894.1 - 0.31 10.9 5.2 0.088 12.7 0.5 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF5089 PF17002.5 KEY70894.1 - 0.43 10.4 7.3 0.31 10.9 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) T3SS_needle_E PF08988.10 KEY70894.1 - 2.8 8.2 5.8 0.6 10.3 1.8 1.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Complex1_LYR PF05347.15 KEY70894.1 - 8 6.6 7.7 38 4.4 0.7 2.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Ribonucleas_3_3 PF14622.6 KEY70895.1 - 1.2e-06 28.7 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KEY70895.1 - 0.00061 20.4 0.0 0.0032 18.0 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KEY70895.1 - 0.028 15.1 0.0 0.058 14.1 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif zf-RING_2 PF13639.6 KEY70897.1 - 4.8e-13 49.2 16.2 2.7e-12 46.8 7.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 KEY70897.1 - 5.5e-09 35.6 2.1 5.5e-09 35.6 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY70897.1 - 1.2e-08 34.7 7.7 1.2e-08 34.7 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY70897.1 - 4.5e-08 32.8 10.6 8.8e-07 28.7 3.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEY70897.1 - 1.8e-07 31.3 3.8 1.8e-07 31.3 3.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KEY70897.1 - 7.6e-07 28.9 14.8 1.3e-06 28.2 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY70897.1 - 0.0015 18.5 4.5 0.0015 18.5 4.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KEY70897.1 - 0.0028 17.7 1.6 0.0028 17.7 1.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEY70897.1 - 0.0032 17.3 12.1 0.0063 16.4 5.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KEY70897.1 - 0.0049 17.2 5.0 0.0049 17.2 5.0 2.2 2 0 0 2 2 2 1 RING-like domain zf-RING_UBOX PF13445.6 KEY70897.1 - 0.006 16.6 6.0 0.006 16.6 6.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger HypA PF01155.19 KEY70897.1 - 0.0082 16.2 0.2 0.0082 16.2 0.2 2.1 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KEY70897.1 - 0.16 12.0 8.0 1.3 9.0 0.4 2.5 2 1 1 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 KEY70897.1 - 0.19 12.0 7.1 0.15 12.4 3.7 2.4 2 0 0 2 2 2 0 zinc-ribbon DNA_ligase_ZBD PF03119.16 KEY70897.1 - 0.52 10.4 4.8 2.7 8.1 0.3 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 KEY70897.1 - 0.7 10.0 8.1 0.91 9.6 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 KEY70897.1 - 0.72 9.5 13.2 0.11 12.1 4.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KEY70897.1 - 1.8 8.4 10.8 0.96 9.3 3.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KEY70897.1 - 7.1 6.9 12.9 19 5.5 4.5 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_2 PF00152.20 KEY70898.1 - 2.1e-71 240.6 0.0 3.4e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KEY70898.1 - 2.9e-18 65.9 0.1 5e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KEY70898.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.13 KEY70899.1 - 3e-41 141.6 0.0 3.9e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY70899.1 - 3.1e-07 29.6 0.0 2.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY70899.1 - 0.00017 21.2 0.0 0.26 10.8 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY70899.1 - 0.00042 21.0 2.1 0.00078 20.1 2.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KEY70899.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GLTP PF08718.11 KEY70900.1 - 3.5e-46 157.2 0.0 4.6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PLDc_2 PF13091.6 KEY70901.1 - 6.5e-14 52.0 0.2 8.5e-05 22.5 0.0 3.8 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 KEY70901.1 - 2e-13 49.9 1.2 4.5e-07 29.8 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif BRO1 PF03097.18 KEY70903.1 - 3e-135 451.0 4.1 3e-135 451.0 4.1 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KEY70903.1 - 8.6e-80 268.2 22.4 2.2e-79 266.9 22.4 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Takusan PF04822.13 KEY70903.1 - 2.3 8.2 9.1 1.5 8.7 6.1 2.4 2 1 0 2 2 2 0 Takusan COG2 PF06148.11 KEY70903.1 - 3.2 7.9 8.4 0.35 10.9 0.3 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Gp58 PF07902.11 KEY70903.1 - 3.4 5.8 14.1 0.7 8.1 9.8 1.8 2 0 0 2 2 2 0 gp58-like protein AAA PF00004.29 KEY70904.1 - 8.1e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY70904.1 - 5e-07 30.1 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY70904.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEY70904.1 - 8.2e-05 22.8 0.0 0.00026 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEY70904.1 - 8.3e-05 22.6 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KEY70904.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY70904.1 - 0.001 19.4 0.0 0.0035 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEY70904.1 - 0.0012 18.6 0.3 0.0027 17.5 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEY70904.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEY70904.1 - 0.0039 16.9 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEY70904.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 KEY70904.1 - 0.027 14.4 0.2 0.12 12.3 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 KEY70904.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEY70904.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KEY70904.1 - 0.17 11.4 0.2 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEY70904.1 - 0.19 11.4 0.1 0.54 10.0 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein S4 PF01479.25 KEY70905.1 - 3.7e-14 52.2 0.0 7.4e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KEY70905.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain Cytochrom_C PF00034.21 KEY70905.1 - 6.6 8.0 5.5 10 7.4 1.3 3.0 2 1 1 3 3 3 0 Cytochrome c Fungal_trans PF04082.18 KEY70906.1 - 9.2e-41 139.6 0.0 1.6e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70906.1 - 3.7e-08 33.4 6.8 8.5e-08 32.2 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL11 PF07400.11 KEY70906.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin 11 PHD PF00628.29 KEY70906.1 - 0.85 9.6 4.9 0.6 10.1 2.9 1.8 2 0 0 2 2 2 0 PHD-finger Fungal_trans PF04082.18 KEY70907.1 - 6.2e-27 94.3 0.0 1.8e-26 92.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70907.1 - 2.4e-09 37.2 7.6 4.2e-09 36.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY70907.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TFIIA PF03153.13 KEY70908.1 - 0.0076 16.3 8.6 0.012 15.6 8.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.12 KEY70908.1 - 0.12 11.0 7.3 0.2 10.2 7.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3246 PF11596.8 KEY70908.1 - 0.13 11.7 0.9 0.18 11.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FAM176 PF14851.6 KEY70908.1 - 1.5 8.5 8.3 1.7 8.3 2.6 2.3 2 0 0 2 2 2 0 FAM176 family DUF4407 PF14362.6 KEY70908.1 - 6.3 6.1 9.6 11 5.2 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGA2 PF07543.12 KEY70908.1 - 6.7 6.7 12.6 0.23 11.5 5.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Amidohydro_1 PF01979.20 KEY70909.1 - 3.2e-81 273.3 0.0 3.7e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY70909.1 - 8.3e-12 45.3 1.0 5.9e-09 35.9 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1729 PF08354.10 KEY70910.1 - 5.5e-158 525.5 0.0 9.5e-158 524.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KEY70910.1 - 2.8e-89 299.8 0.0 4.4e-87 292.6 0.0 3.0 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KEY70910.1 - 4.6e-53 179.0 0.0 1e-52 177.8 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 KEY70910.1 - 1.1e-37 128.3 0.0 2.8e-37 127.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KEY70910.1 - 1.3e-37 128.7 0.0 7e-37 126.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 KEY70910.1 - 6.1e-37 127.6 0.0 2.5e-36 125.6 0.0 2.0 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KEY70910.1 - 4.5e-24 85.1 0.0 1.3e-23 83.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 KEY70911.1 - 4.4e-76 255.0 0.2 1.4e-75 253.4 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KEY70911.1 - 8.9e-73 244.0 0.3 2e-72 242.8 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KEY70911.1 - 2.7e-22 79.6 0.0 6.7e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KEY70911.1 - 1e-17 64.3 0.0 2.7e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KEY70911.1 - 1.1e-11 44.7 0.0 4e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KEY70911.1 - 1.4e-05 25.1 0.2 0.00044 20.2 0.0 2.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KEY70911.1 - 5.5e-05 22.7 0.2 0.00027 20.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase 4PPT_N PF17837.1 KEY70911.1 - 0.033 14.3 0.2 0.53 10.4 0.8 2.5 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain LSM PF01423.22 KEY70912.1 - 5.1e-15 54.9 0.0 7.5e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEY70912.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KEY70912.1 - 0.43 9.3 4.5 0.46 9.2 4.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PPR_2 PF13041.6 KEY70913.1 - 2.5e-08 34.0 0.0 0.34 11.1 0.0 5.4 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 KEY70913.1 - 9e-06 25.6 0.2 1.6 9.1 0.0 5.7 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 KEY70913.1 - 1.2e-05 25.3 0.1 0.031 14.4 0.1 4.3 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KEY70913.1 - 0.0073 15.7 0.2 0.19 11.0 0.1 2.8 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KEY70913.1 - 0.36 10.6 2.1 0.57 9.9 0.0 2.5 3 0 0 3 3 3 0 PPR repeat Zn_clus PF00172.18 KEY70914.1 - 2.4e-06 27.6 11.0 4.9e-06 26.6 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 KEY70915.1 - 1.9e-46 158.3 0.0 8.2e-46 156.3 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KEY70915.1 - 1.8e-36 125.9 0.0 2.7e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KEY70915.1 - 1.7e-26 92.7 3.7 4.9e-26 91.3 3.7 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KEY70915.1 - 5.4e-11 42.0 0.1 1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KEY70915.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 HeH/LEM domain DARPP-32 PF05395.12 KEY70915.1 - 2.7 8.2 8.7 0.2 11.9 2.3 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Ferrochelatase PF00762.19 KEY70916.1 - 1.5e-98 329.8 0.0 1.8e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KEY70916.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) UNC-79 PF14776.6 KEY70916.1 - 0.21 10.3 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Septin PF00735.18 KEY70917.1 - 1.6e-118 395.1 0.2 2.9e-118 394.2 0.2 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KEY70917.1 - 2.9e-08 33.8 0.6 6.7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY70917.1 - 2.3e-05 24.1 1.4 0.00043 19.9 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY70917.1 - 8.1e-05 22.6 2.1 0.003 17.5 0.8 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KEY70917.1 - 9.6e-05 22.9 0.6 0.03 14.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KEY70917.1 - 0.0011 18.4 1.3 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KEY70917.1 - 0.0023 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KEY70917.1 - 0.0025 18.2 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KEY70917.1 - 0.011 15.4 0.2 0.06 12.9 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 KEY70917.1 - 0.014 15.6 0.2 0.054 13.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY70917.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEY70917.1 - 0.067 13.6 1.0 0.8 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KEY70917.1 - 0.075 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KEY70917.1 - 0.092 12.5 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KEY70917.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KEY70917.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 KEY70917.1 - 0.22 11.6 7.5 1.2 9.2 0.0 3.3 3 1 0 3 3 2 0 Dynamin family DUF87 PF01935.17 KEY70917.1 - 1.3 9.0 4.2 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KEY70917.1 - 1.4 8.4 6.0 2.3 7.7 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fis1_TPR_C PF14853.6 KEY70918.1 - 4.8e-26 90.6 2.0 8.5e-26 89.8 2.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KEY70918.1 - 4.8e-18 64.5 1.0 6.1e-18 64.2 0.1 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KEY70918.1 - 0.0044 17.0 1.5 0.01 15.9 1.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.11 KEY70919.1 - 1.2e-36 125.1 0.9 3.4e-35 120.5 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 AA_kinase PF00696.28 KEY70919.1 - 0.01 15.4 1.3 0.017 14.7 1.2 1.4 1 1 0 1 1 1 0 Amino acid kinase family PKI PF02827.16 KEY70919.1 - 0.028 14.6 2.0 2.7 8.3 0.1 2.5 1 1 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Atg14 PF10186.9 KEY70919.1 - 0.049 12.7 1.0 0.061 12.4 1.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Troponin PF00992.20 KEY70919.1 - 0.05 13.9 0.8 9.9 6.5 0.2 2.2 1 1 1 2 2 2 0 Troponin Retrotrans_gag PF03732.17 KEY70919.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein LEAP-2 PF07359.11 KEY70920.1 - 0.0086 15.9 0.4 0.018 14.8 0.4 1.6 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) TatD_DNase PF01026.21 KEY70921.1 - 1.1e-27 97.0 0.0 2.1e-27 96.2 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 KEY70922.1 - 1.3e-23 83.4 0.2 2.1e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70922.1 - 1.2e-07 31.7 10.5 2.3e-07 30.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxase_2 PF12766.7 KEY70923.1 - 8.3e-20 71.3 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CHASE3 PF05227.13 KEY70924.1 - 0.08 12.8 0.4 0.08 12.8 0.4 2.9 3 1 1 4 4 4 0 CHASE3 domain Pkinase PF00069.25 KEY70925.1 - 2.5e-22 79.5 0.0 3.6e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KEY70925.1 - 3e-09 37.4 13.9 1.2e-05 26.0 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 KEY70925.1 - 4.5e-09 35.8 1.3 0.23 11.8 0.1 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KEY70925.1 - 2.2e-05 24.7 2.2 0.067 13.6 0.0 4.6 3 1 1 4 4 4 1 HEAT repeats Pkinase_Tyr PF07714.17 KEY70925.1 - 4.4e-05 22.9 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY70925.1 - 0.00076 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.7 KEY70925.1 - 0.034 14.2 0.0 26 4.8 0.0 3.2 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 LRR_9 PF14580.6 KEY70926.1 - 1.3e-53 181.1 0.0 2.3e-53 180.3 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KEY70926.1 - 9.2e-09 35.5 1.6 0.00015 22.1 2.0 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY70926.1 - 1.4e-06 28.0 4.0 2.5e-06 27.1 1.1 2.8 4 0 0 4 4 4 1 Leucine rich repeat DUF4349 PF14257.6 KEY70926.1 - 0.051 13.0 2.8 0.1 12.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) NAM-associated PF14303.6 KEY70926.1 - 0.056 14.2 1.0 0.082 13.6 1.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CBFD_NFYB_HMF PF00808.23 KEY70927.1 - 2.4e-11 43.8 0.2 3.8e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEY70927.1 - 0.021 15.2 0.1 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 KEY70927.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CENP-W protein RE_AccI PF09545.10 KEY70927.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease Voltage_CLC PF00654.20 KEY70928.1 - 4.9e-88 295.8 26.2 4.9e-88 295.8 26.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEY70928.1 - 1.5e-11 44.6 0.3 1.2e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain Meckelin PF09773.9 KEY70928.1 - 0.31 9.1 1.4 0.47 8.5 1.4 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) CoA_binding_3 PF13727.6 KEY70928.1 - 3.6 7.6 7.1 2.7 8.0 0.3 3.2 3 0 0 3 3 3 0 CoA-binding domain EamA PF00892.20 KEY70929.1 - 0.0072 16.5 17.6 0.037 14.2 17.6 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KEY70929.1 - 0.1 12.6 3.2 0.15 12.1 3.2 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF2754 PF10953.8 KEY70929.1 - 0.11 12.8 1.3 2 8.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) TFIIA_gamma_C PF02751.14 KEY70930.1 - 3.1e-24 84.8 2.1 5e-24 84.2 2.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KEY70930.1 - 2.1e-23 82.1 0.3 2.9e-23 81.6 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.21 KEY70931.1 - 8.3e-22 77.3 35.0 1.7e-14 53.9 12.5 2.5 3 0 0 3 3 3 2 ATP synthase subunit C DUF3671 PF12420.8 KEY70931.1 - 0.22 11.6 0.2 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function SLATT_5 PF18160.1 KEY70931.1 - 0.4 10.0 0.1 0.4 10.0 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MoCF_biosynth PF00994.24 KEY70932.1 - 1.9e-52 176.8 0.3 4.5e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KEY70932.1 - 5.3e-39 133.5 3.4 1.3e-38 132.2 3.6 1.6 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KEY70932.1 - 3.1e-15 56.1 0.7 9.8e-15 54.5 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) RNase_P_Rpp14 PF01900.19 KEY70933.1 - 1.5e-39 134.4 0.0 1.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KEY70934.1 - 4.2e-81 272.3 0.6 5.5e-81 271.9 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KEY70934.1 - 0.0027 17.6 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KEY70934.1 - 0.0056 15.7 0.2 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KEY70934.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEY70934.1 - 0.045 13.0 0.5 0.2 10.9 0.0 2.2 3 0 0 3 3 3 0 Zeta toxin CLP1_P PF16575.5 KEY70934.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 KEY70934.1 - 0.093 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KEY70934.1 - 0.11 12.7 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KEY70934.1 - 0.17 11.3 0.1 2.1 7.7 0.1 2.1 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 KEY70934.1 - 0.57 10.7 3.5 1.9 9.0 0.2 2.8 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KEY70934.1 - 0.86 10.0 3.9 0.59 10.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 KEY70934.1 - 4.2 8.0 9.2 17 6.1 4.6 2.6 3 0 0 3 3 2 0 SlyX cNMP_binding PF00027.29 KEY70935.1 - 3.6e-28 97.5 1.0 7.8e-15 54.7 0.1 5.5 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KEY70935.1 - 3.3e-15 56.8 6.5 1.6e-13 51.3 6.5 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase Zip PF02535.22 KEY70936.1 - 0.015 14.6 0.1 0.016 14.5 0.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 KEY70936.1 - 6.5 6.7 10.2 9.3 6.2 10.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pyridoxal_deC PF00282.19 KEY70937.1 - 5.9e-96 321.4 0.0 7.8e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.11 KEY70937.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) EMP70 PF02990.16 KEY70938.1 - 1.2e-198 661.0 0.0 1.5e-198 660.7 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Bul1_C PF04426.12 KEY70939.1 - 0.00011 21.7 0.0 0.00048 19.6 0.0 1.8 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.12 KEY70939.1 - 0.0024 16.7 0.0 0.0085 14.9 0.0 1.7 2 0 0 2 2 2 1 Bul1 N terminus Arrestin_C PF02752.22 KEY70939.1 - 0.01 16.3 0.4 0.65 10.4 0.7 2.7 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Zip PF02535.22 KEY70941.1 - 9e-44 150.0 5.1 1.9e-43 149.0 5.1 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.18 KEY70942.1 - 1.8e-07 31.1 0.1 2.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.12 KEY70943.1 - 1.4e-22 80.3 5.4 1.4e-22 80.3 5.4 3.7 2 1 1 3 3 3 2 Hamartin protein Dehydrin PF00257.19 KEY70943.1 - 2.5 8.6 8.8 9 6.8 8.8 2.0 1 0 0 1 1 1 0 Dehydrin DJ-1_PfpI PF01965.24 KEY70944.1 - 8.7e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KEY70944.1 - 0.00018 21.2 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 KEY70944.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family SAP PF02037.27 KEY70945.1 - 7.1e-11 41.6 0.2 1.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 SAP domain CPSase_sm_chain PF00988.22 KEY70946.1 - 4.6e-46 155.8 0.0 8.9e-46 154.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KEY70946.1 - 3.8e-43 147.5 0.0 5.2e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEY70946.1 - 0.00011 22.1 0.0 0.00051 19.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 KEY70946.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family ETF PF01012.21 KEY70947.1 - 1e-41 142.8 0.6 1.3e-41 142.5 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 KEY70948.1 - 1.1e-32 112.5 0.1 2.4e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KEY70949.1 - 2.2e-31 107.5 0.2 2.8e-15 55.9 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY70949.1 - 1.7e-05 24.4 0.0 0.13 11.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY70949.1 - 5.9e-05 23.1 0.0 0.031 14.4 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 KEY70949.1 - 0.017 15.4 0.0 8.8 6.5 0.0 3.4 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 KEY70949.1 - 0.06 13.3 0.1 5.6 7.0 0.1 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.8 KEY70949.1 - 0.12 12.4 0.2 22 5.2 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 FAD_binding_1 PF00667.20 KEY70950.1 - 5.9e-31 107.8 0.0 1.2e-30 106.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 KEY70950.1 - 7.1e-29 100.8 0.0 1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEY70950.1 - 5.1e-12 46.4 0.0 1.2e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Asp PF00026.23 KEY70951.1 - 4.9e-12 45.9 0.1 3e-11 43.3 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Pox_G5 PF04599.12 KEY70951.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein F-box-like PF12937.7 KEY70953.1 - 1.4e-09 37.7 0.1 2.6e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY70953.1 - 1.8e-08 34.0 0.7 3.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain WPP PF13943.6 KEY70953.1 - 0.023 15.1 0.5 0.064 13.7 0.5 1.7 1 0 0 1 1 1 0 WPP domain UIM PF02809.20 KEY70953.1 - 0.036 14.0 10.4 0.031 14.2 3.8 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif HypA PF01155.19 KEY70954.1 - 0.0015 18.5 22.2 0.096 12.7 1.3 3.4 3 0 0 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 KEY70954.1 - 0.047 13.9 17.4 0.21 11.8 1.9 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger Siva PF05458.12 KEY70954.1 - 0.52 10.0 10.2 0.37 10.4 1.1 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) IBR PF01485.21 KEY70954.1 - 1.4 9.2 28.6 1.1 9.5 4.8 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 KEY70954.1 - 3.6 7.7 35.7 0.41 10.7 3.6 3.9 2 2 1 3 3 3 0 Double zinc ribbon Clr2 PF10383.9 KEY70955.1 - 9.2e-08 33.0 3.7 8e-07 29.9 0.0 3.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KEY70955.1 - 1.7e-06 28.8 3.6 6.2e-06 27.0 3.6 2.0 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 SMC_Nse1 PF07574.13 KEY70956.1 - 3.1e-68 229.5 0.0 4e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KEY70956.1 - 4.9e-15 55.6 8.6 7.6e-15 54.9 8.6 1.3 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.22 KEY70956.1 - 0.021 14.7 2.9 0.021 14.7 2.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 KEY70956.1 - 0.13 12.5 1.8 0.24 11.7 1.8 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Rpr2 PF04032.16 KEY70956.1 - 0.42 10.9 2.2 0.9 9.9 2.2 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SPRY PF00622.28 KEY70958.1 - 0.0024 18.0 0.1 0.032 14.3 0.0 2.5 3 0 0 3 3 3 1 SPRY domain GATA PF00320.27 KEY70959.1 - 1.7e-29 101.1 16.4 1.1e-15 56.9 3.0 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KEY70959.1 - 5.6e-07 29.0 2.4 0.0088 15.5 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KEY70959.1 - 0.00047 20.2 3.6 0.094 12.8 0.3 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KEY70959.1 - 0.0017 18.4 7.9 0.065 13.4 0.1 2.8 3 0 0 3 3 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KEY70959.1 - 0.0028 17.8 4.6 0.91 9.7 0.3 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KEY70959.1 - 0.0062 16.4 3.0 0.79 9.6 0.1 2.5 2 0 0 2 2 2 2 Domain found in IF2B/IF5 zf-RRN7 PF11781.8 KEY70959.1 - 0.0071 16.0 7.4 0.16 11.7 0.9 2.8 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ad_cyc_g-alpha PF08509.11 KEY70959.1 - 0.031 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain DZR PF12773.7 KEY70959.1 - 0.4 10.7 16.8 0.58 10.2 1.1 3.3 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KEY70959.1 - 0.51 10.3 13.3 0.17 11.8 0.6 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain NRIP1_repr_3 PF15689.5 KEY70959.1 - 2.1 8.7 5.3 28 5.1 0.0 3.6 2 1 1 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 zf-ribbon_3 PF13248.6 KEY70959.1 - 2.2 7.8 11.2 32 4.1 0.3 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Homeobox_KN PF05920.11 KEY70960.1 - 2.6e-16 59.2 2.1 6.6e-16 57.9 2.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KEY70960.1 - 1.7e-11 44.0 0.7 5.9e-05 23.0 0.0 4.4 4 0 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KEY70960.1 - 5e-06 26.3 0.7 1.3e-05 24.9 0.7 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KEY70960.1 - 0.0015 18.9 13.9 0.041 14.3 3.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY70960.1 - 0.0033 18.1 3.8 0.0033 18.1 3.8 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger DUF4667 PF15700.5 KEY70960.1 - 3.6 7.6 11.5 0.72 9.9 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) MFS_1 PF07690.16 KEY70964.1 - 1.1e-25 90.4 27.4 1.1e-25 90.4 27.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MTHFR PF02219.17 KEY70966.1 - 2.3e-112 375.0 0.0 3.1e-112 374.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RRM_1 PF00076.22 KEY70967.1 - 5.9e-08 32.4 0.2 7e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KEY70967.1 - 2e-07 31.2 0.0 4.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KEY70967.1 - 3.2e-06 27.1 0.1 0.0057 16.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEY70967.1 - 5.2e-05 23.0 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif zf-CCCH PF00642.24 KEY70967.1 - 0.0011 18.8 5.2 0.002 18.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_23 PF13476.6 KEY70967.1 - 0.068 13.7 3.5 0.12 12.8 3.5 1.5 1 0 0 1 1 1 0 AAA domain DUF1330 PF07045.11 KEY70967.1 - 0.089 13.1 0.1 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) zf_CCCH_4 PF18345.1 KEY70967.1 - 0.094 12.8 2.8 0.18 11.9 2.8 1.5 1 0 0 1 1 1 0 Zinc finger domain Tho2 PF11262.8 KEY70967.1 - 0.11 11.6 2.2 0.19 10.9 2.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-CCCH_2 PF14608.6 KEY70967.1 - 0.16 12.5 2.1 0.28 11.7 2.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Exonuc_VII_L PF02601.15 KEY70967.1 - 0.36 10.3 4.7 0.56 9.7 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PHM7_cyt PF14703.6 KEY70967.1 - 0.55 10.4 6.1 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Spc7 PF08317.11 KEY70967.1 - 1.8 7.3 13.9 2.9 6.7 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KEY70967.1 - 10 3.5 18.1 14 3.1 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GTP_EFTU PF00009.27 KEY70968.1 - 1.2e-66 223.9 0.4 1.8e-66 223.4 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KEY70968.1 - 4.7e-34 116.8 0.0 2.5e-33 114.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KEY70968.1 - 4e-22 78.0 0.0 1.4e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY70968.1 - 1.9e-13 50.6 0.0 1e-12 48.3 0.0 2.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEY70968.1 - 1.1e-11 44.6 0.0 3.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KEY70968.1 - 0.00032 20.7 0.2 0.00071 19.6 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sulfatase PF00884.23 KEY70968.1 - 0.045 13.1 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PAD_M PF08527.10 KEY70968.1 - 0.089 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain OTCace PF00185.24 KEY70969.1 - 0.25 11.4 0.7 0.79 9.8 0.1 2.0 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Solute_trans_a PF03619.16 KEY70970.1 - 5.2e-99 331.1 10.3 6.2e-99 330.8 10.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TRAF6_Z2 PF18048.1 KEY70971.1 - 0.11 12.6 0.9 0.23 11.6 0.9 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_6 PF13912.6 KEY70971.1 - 0.32 11.1 1.7 2 8.5 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_clus PF00172.18 KEY70971.1 - 0.63 10.2 12.6 0.03 14.5 6.8 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 KEY70971.1 - 2 8.5 5.1 0.26 11.3 0.8 1.8 2 0 0 2 2 2 0 BED zinc finger Sec5 PF15469.6 KEY70972.1 - 4.4e-37 127.8 0.1 5.1e-36 124.3 0.0 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 KEY70972.1 - 0.00067 19.7 0.5 0.0036 17.4 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Iso_dh PF00180.20 KEY70973.1 - 1.9e-100 336.4 0.0 2.4e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KEY70973.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 KEY70973.1 - 0.026 14.6 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif F-box PF00646.33 KEY70974.1 - 0.00047 20.0 0.8 0.001 18.9 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KEY70974.1 - 0.024 14.5 0.4 0.058 13.3 0.4 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KEY70975.1 - 1.4e-07 31.2 0.5 5.7e-07 29.3 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY70975.1 - 6.9e-06 25.8 0.3 1.7e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain BLOC1S3 PF15753.5 KEY70975.1 - 0.0035 17.5 2.4 0.0035 17.5 2.4 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 APG6_N PF17675.1 KEY70975.1 - 0.014 15.9 2.6 0.014 15.9 2.6 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KEY70975.1 - 0.075 13.2 2.3 0.075 13.2 0.4 1.9 2 0 0 2 2 2 0 Tropomyosin like F-box-like_2 PF13013.6 KEY70975.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Spc7 PF08317.11 KEY70975.1 - 0.1 11.5 2.4 0.18 10.7 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 KEY70975.1 - 0.19 11.9 3.1 0.41 10.9 3.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein FapA PF03961.13 KEY70975.1 - 0.2 10.3 0.7 0.31 9.6 0.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KEY70975.1 - 0.28 11.7 3.4 6.7 7.3 0.2 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KEY70975.1 - 0.31 11.4 2.4 17 5.8 0.2 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 KEY70975.1 - 0.32 11.0 4.8 0.99 9.4 4.8 1.8 1 0 0 1 1 1 0 FlxA-like protein SKA2 PF16740.5 KEY70975.1 - 1.6 8.5 6.5 21 4.9 0.1 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Transglut_core PF01841.19 KEY70976.1 - 1.2e-12 48.2 0.0 2.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KEY70976.1 - 0.28 12.2 0.0 0.28 12.2 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase MFS_1 PF07690.16 KEY70977.1 - 1.1e-44 152.8 37.0 1.1e-44 152.8 37.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY70977.1 - 2.5e-13 49.7 18.6 6.9e-13 48.2 18.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Glycos_transf_4 PF00953.21 KEY70978.1 - 2e-30 105.9 8.5 2e-30 105.9 8.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 PHD PF00628.29 KEY70979.1 - 4.9e-08 32.7 10.3 8.1e-08 32.0 9.5 1.8 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 KEY70979.1 - 0.00036 20.9 0.0 0.00099 19.5 0.0 1.7 1 0 0 1 1 1 1 SET domain E1_DerP2_DerF2 PF02221.15 KEY70980.1 - 5.5e-27 94.8 0.4 6.5e-27 94.6 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KEY70980.1 - 0.0029 18.0 0.0 0.0063 16.9 0.0 1.5 1 1 0 1 1 1 1 ML-like domain ATP-synt_F PF01990.17 KEY70981.1 - 1.2e-33 115.3 0.1 1.3e-33 115.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.9 KEY70982.1 - 2.5e-34 117.7 0.9 3.3e-34 117.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Aconitase PF00330.20 KEY70984.1 - 1.4e-160 535.4 0.0 1.8e-160 534.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEY70984.1 - 4.3e-39 133.8 0.0 9.4e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.9 KEY70985.1 - 2.5e-12 46.9 0.0 3.6e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KEY70985.1 - 0.057 14.1 0.1 0.74 10.6 0.1 2.6 2 1 0 2 2 2 0 Methyltransferase domain EF-hand_7 PF13499.6 KEY70986.1 - 4.4e-24 84.7 7.9 6.7e-16 58.5 1.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KEY70986.1 - 6.6e-23 78.5 12.8 4.2e-08 32.2 0.2 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KEY70986.1 - 4.1e-22 76.2 5.4 5.2e-06 26.0 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KEY70986.1 - 4e-15 54.5 11.1 4.9e-05 22.6 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KEY70986.1 - 4.7e-13 48.8 12.1 0.00077 19.3 0.9 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KEY70986.1 - 1e-08 35.0 6.7 0.0072 16.3 0.2 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KEY70986.1 - 9e-05 22.7 1.1 0.015 15.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KEY70986.1 - 0.034 14.5 4.1 1 9.7 0.5 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KEY70986.1 - 0.13 12.6 1.4 8.9 6.7 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain Hemerythrin PF01814.23 KEY70987.1 - 9e-07 29.6 0.4 1.2e-06 29.1 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cytochrom_B562 PF07361.11 KEY70987.1 - 0.18 12.5 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b562 CDC45 PF02724.14 KEY70988.1 - 6.6e-247 820.9 0.2 6.7e-246 817.6 0.2 2.8 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KEY70988.1 - 4.7 6.4 31.3 1.8 7.8 15.9 2.1 2 0 0 2 2 2 0 BUD22 TFIIF_alpha PF05793.12 KEY70988.1 - 5.2 5.5 22.0 0.24 9.9 10.7 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Methyltransf_23 PF13489.6 KEY70989.1 - 4.8e-14 52.5 0.0 6.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY70989.1 - 1.3e-06 29.1 0.0 6.4e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY70989.1 - 2.5e-06 28.1 0.0 4.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY70989.1 - 7.5e-06 26.5 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY70989.1 - 6.6e-05 22.7 0.0 0.0012 18.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KEY70989.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEY70989.1 - 0.0054 16.0 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KEY70989.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Phage_portal PF04860.12 KEY70989.1 - 0.13 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein Fungal_trans PF04082.18 KEY70990.1 - 2.4e-17 62.8 0.0 3.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY70990.1 - 4.7e-09 36.2 10.2 4.7e-09 36.2 10.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEY70991.1 - 4.5e-34 117.9 60.2 4.7e-32 111.3 60.2 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MitMem_reg PF13012.6 KEY70992.1 - 9.4e-11 42.1 0.5 1.9e-10 41.2 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KEY70992.1 - 1e-08 35.1 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PAS_9 PF13426.7 KEY70992.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain ADH_N PF08240.12 KEY70993.1 - 2.4e-26 91.8 1.0 6.2e-26 90.4 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY70993.1 - 2.3e-16 60.0 2.1 1.5e-15 57.3 2.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY70993.1 - 3.7e-09 36.4 0.2 0.0003 20.3 0.1 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY70993.1 - 0.00027 22.0 0.0 0.00062 20.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEY70993.1 - 0.0041 16.4 0.3 0.0041 16.4 0.3 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KEY70993.1 - 0.0069 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KEY70993.1 - 0.0071 15.9 0.2 0.015 14.9 0.1 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF281 PF03436.13 KEY70993.1 - 0.032 14.6 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Shikimate_DH PF01488.20 KEY70993.1 - 0.04 14.0 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 KEY70993.1 - 0.046 13.8 1.2 0.057 13.5 0.2 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KEY70993.1 - 0.053 13.4 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEY70993.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 KEY70993.1 - 0.063 13.5 3.6 0.18 12.0 0.3 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain PEP-CTERM PF07589.11 KEY70993.1 - 0.25 11.5 1.0 0.56 10.4 1.0 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Vps5 PF09325.10 KEY70995.1 - 5.4e-11 42.5 0.2 8.7e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KEY70995.1 - 1.1e-07 31.8 0.1 2.6e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 PX domain NST1 PF13945.6 KEY70995.1 - 0.019 15.1 2.1 0.019 15.1 2.1 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator TPR_12 PF13424.6 KEY70995.1 - 0.028 14.7 0.3 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY70995.1 - 0.26 11.2 0.8 0.81 9.6 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BCIP PF13862.6 KEY70996.1 - 4.8e-67 225.7 0.0 5.9e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DEC-1_C PF04626.13 KEY70996.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Cupin_8 PF13621.6 KEY70997.1 - 1.4e-33 116.7 0.0 2.7e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain WD40 PF00400.32 KEY70997.1 - 8.8e-25 86.5 11.8 2.8e-06 27.9 0.8 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY70997.1 - 2e-07 31.2 0.1 0.22 11.9 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY70997.1 - 5.1e-06 25.4 7.8 0.032 12.9 0.2 5.0 3 2 2 5 5 5 2 Nucleoporin Nup120/160 JmjC PF02373.22 KEY70997.1 - 9.2e-06 26.1 0.0 0.00066 20.1 0.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KEY70997.1 - 0.0036 16.8 0.0 0.29 10.6 0.0 2.6 2 0 0 2 2 2 1 Cupin superfamily protein Seryl_tRNA_N PF02403.22 KEY70997.1 - 0.8 10.0 4.1 1.7 8.9 1.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.6 KEY70998.1 - 0.01 16.0 6.8 0.01 16.0 6.8 3.6 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit GCN5L1 PF06320.13 KEY70998.1 - 0.058 13.5 6.1 3.2 7.9 2.2 2.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Wtap PF17098.5 KEY70998.1 - 0.058 13.3 6.4 0.054 13.4 3.1 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family bZIP_1 PF00170.21 KEY70998.1 - 0.1 12.7 11.8 2.5 8.2 4.5 2.6 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 KEY70998.1 - 0.25 12.0 12.4 0.41 11.3 2.8 2.8 3 0 0 3 3 2 0 Initiation control protein YabA Ax_dynein_light PF10211.9 KEY70998.1 - 0.26 11.2 12.8 3.9 7.4 0.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Sec34 PF04136.15 KEY70998.1 - 0.28 11.1 5.3 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Sec34-like family Cnn_1N PF07989.11 KEY70998.1 - 0.41 10.8 9.5 7.2 6.8 3.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 KEY70998.1 - 0.48 10.2 14.3 7.6 6.3 14.3 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KEY70998.1 - 0.74 9.6 11.5 3.6 7.4 5.7 2.5 2 0 0 2 2 2 0 Septum formation initiator Snapin_Pallidin PF14712.6 KEY70998.1 - 2.4 8.6 8.2 1.5 9.3 0.5 2.6 2 0 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 KEY70998.1 - 2.4 8.8 12.5 16 6.2 2.5 3.5 3 0 0 3 3 3 0 SlyX eIF-3c_N PF05470.12 KEY70998.1 - 2.5 6.3 8.3 0.76 8.0 2.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Rootletin PF15035.6 KEY70998.1 - 3.3 7.7 19.1 0.031 14.3 4.2 3.2 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 KEY70998.1 - 3.7 7.6 17.4 4.4 7.4 1.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.6 KEY70998.1 - 5.2 7.0 7.1 7.9 6.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) BLOC1_2 PF10046.9 KEY70998.1 - 6.2 7.2 8.4 26 5.2 2.8 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 KEY70998.1 - 6.4 6.4 11.7 14 5.3 0.4 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 KEY70998.1 - 8.6 5.7 16.2 2.8 7.3 8.7 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KEY70998.1 - 9.2 5.0 12.3 46 2.7 12.3 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein VASt PF16016.5 KEY70999.1 - 5.6e-39 134.0 0.0 9.5e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KEY70999.1 - 4.3e-23 81.4 0.0 7.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.12 KEY70999.1 - 0.14 11.4 7.1 0.32 10.3 0.4 2.3 2 0 0 2 2 2 0 NOA36 protein AAA_6 PF12774.7 KEY71002.1 - 5e-127 423.4 0.0 3.6e-126 420.6 0.0 2.7 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KEY71002.1 - 1.9e-116 390.0 11.9 1.9e-116 390.0 11.9 4.7 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KEY71002.1 - 3.1e-116 388.7 6.8 3.1e-116 388.7 6.8 6.5 6 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KEY71002.1 - 2.1e-74 249.4 1.2 2.1e-74 249.4 1.2 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KEY71002.1 - 2.1e-65 220.6 0.0 1.2e-64 218.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KEY71002.1 - 3.7e-42 143.9 0.3 4.5e-36 124.0 0.0 4.9 6 0 0 6 6 4 2 P-loop containing dynein motor region MT PF12777.7 KEY71002.1 - 5.4e-41 140.8 8.4 1.2e-40 139.6 8.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KEY71002.1 - 1e-31 109.8 0.0 3.4e-12 46.5 0.0 6.5 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KEY71002.1 - 7.1e-29 100.3 0.2 5.1e-27 94.3 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KEY71002.1 - 1.6e-27 96.4 0.0 4e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KEY71002.1 - 3.2e-14 53.5 0.0 0.0012 19.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY71002.1 - 1.2e-13 51.5 5.1 0.0096 16.2 0.0 6.3 5 1 1 6 6 5 3 AAA domain Dynein_AAA_lid PF17852.1 KEY71002.1 - 2.3e-13 50.4 0.0 8.7e-13 48.5 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KEY71002.1 - 3.5e-11 43.8 0.1 1.8 8.9 0.0 7.3 6 0 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.6 KEY71002.1 - 1.2e-09 38.4 0.9 0.46 10.6 0.1 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 KEY71002.1 - 2.3e-09 37.9 0.7 0.087 13.4 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA_lid_1 PF17857.1 KEY71002.1 - 4.1e-06 26.9 0.3 0.00026 21.2 0.0 3.9 3 0 0 3 3 3 1 AAA+ lid domain T2SSE PF00437.20 KEY71002.1 - 5e-05 22.5 0.0 0.037 13.1 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 KEY71002.1 - 5.4e-05 22.8 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KEY71002.1 - 0.00028 20.3 1.1 0.67 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KEY71002.1 - 0.00075 20.0 1.1 7.5 7.1 0.0 4.8 4 0 0 4 4 3 0 ABC transporter AAA_30 PF13604.6 KEY71002.1 - 0.001 18.8 2.3 39 3.9 0.0 5.3 6 0 0 6 6 5 0 AAA domain AAA_19 PF13245.6 KEY71002.1 - 0.0011 19.3 2.1 0.28 11.5 0.0 4.4 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 KEY71002.1 - 0.0018 18.0 0.3 0.63 9.8 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 KEY71002.1 - 0.0023 17.7 0.8 11 5.7 0.0 4.6 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 KEY71002.1 - 0.0046 16.6 0.9 0.25 10.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KEY71002.1 - 0.011 16.1 0.2 29 5.1 0.0 4.6 4 0 0 4 4 4 0 RNA helicase APG6_N PF17675.1 KEY71002.1 - 0.018 15.6 0.4 0.018 15.6 0.4 5.5 5 0 0 5 5 3 0 Apg6 coiled-coil region FtsK_SpoIIIE PF01580.18 KEY71002.1 - 0.02 14.3 2.1 2.4 7.5 0.0 3.9 4 0 0 4 4 3 0 FtsK/SpoIIIE family Rad17 PF03215.15 KEY71002.1 - 0.062 13.2 0.1 6.7 6.6 0.0 3.5 4 0 0 4 4 3 0 Rad17 P-loop domain Hemerythrin PF01814.23 KEY71002.1 - 0.093 13.4 1.0 0.96 10.1 0.1 3.3 3 0 0 3 3 1 0 Hemerythrin HHE cation binding domain PduV-EutP PF10662.9 KEY71002.1 - 0.62 9.8 3.0 11 5.7 0.1 3.8 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF4482 PF14818.6 KEY71002.1 - 2.8 8.8 14.6 24 5.8 0.0 3.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4482) NACHT PF05729.12 KEY71002.1 - 3.8 7.4 6.1 31 4.4 0.0 4.2 4 0 0 4 4 3 0 NACHT domain Peptidase_M13 PF01431.21 KEY71003.1 - 5.1e-15 55.6 0.4 7.2e-15 55.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 HET PF06985.11 KEY71004.1 - 1e-26 94.0 0.1 3.3e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Zwint PF15556.6 KEY71007.1 - 0.03 13.8 1.4 0.042 13.3 1.4 1.1 1 0 0 1 1 1 0 ZW10 interactor GATase_6 PF13522.6 KEY71007.1 - 0.095 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase domain DDE_Tnp_1_7 PF13843.6 KEY71009.1 - 1.5e-29 103.4 0.0 3.2e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Transposase IS4 DNA_pol_phi PF04931.13 KEY71009.1 - 2.1 6.3 3.3 2.9 5.9 3.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FA_desaturase PF00487.24 KEY71010.1 - 5.7e-19 68.9 15.6 8.9e-19 68.3 15.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_trans_2_3 PF13632.6 KEY71010.1 - 0.043 13.7 2.2 0.09 12.7 2.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Annexin PF00191.20 KEY71012.1 - 3.3e-72 238.5 4.7 3.7e-18 65.4 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 KEY71012.1 - 0.00039 20.2 0.8 4.1 7.3 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) Acetyltransf_11 PF13720.6 KEY71012.1 - 0.0053 17.2 2.1 14 6.2 0.0 3.8 4 0 0 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PCM1_C PF15717.5 KEY71013.1 - 1 8.0 11.1 1.5 7.4 11.1 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus GREB1 PF15782.5 KEY71013.1 - 2.2 5.3 10.5 2.3 5.2 10.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer adh_short PF00106.25 KEY71015.1 - 8.5e-15 54.7 0.0 3.1e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY71015.1 - 0.012 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 KEY71015.1 - 0.1 12.0 0.1 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Abhydrolase_1 PF00561.20 KEY71017.1 - 2.9e-19 69.7 0.1 7.4e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY71017.1 - 4.7e-17 63.3 1.5 4.7e-17 63.3 1.5 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY71017.1 - 2.9e-12 46.4 0.0 7.1e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KEY71017.1 - 0.00049 19.1 0.0 0.00072 18.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Ndr PF03096.14 KEY71017.1 - 0.0054 15.5 0.0 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_8 PF06259.12 KEY71017.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Chlorophyllase PF07224.11 KEY71017.1 - 0.026 13.6 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 KEY71017.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ntox22 PF15527.6 KEY71017.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 22 MFS_1 PF07690.16 KEY71018.1 - 2.9e-31 108.7 28.8 2.9e-31 108.7 28.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WH2 PF02205.20 KEY71020.1 - 2.1e-09 36.9 0.2 2.1e-09 36.9 0.2 3.0 4 0 0 4 4 4 1 WH2 motif Ribosomal_L37 PF08561.10 KEY71021.1 - 1.2e-39 135.6 2.1 1.4e-39 135.3 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.9 KEY71022.1 - 0.066 13.7 0.0 0.079 13.5 0.0 1.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 RRM_1 PF00076.22 KEY71023.1 - 5.7e-37 125.4 0.1 1e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY71023.1 - 0.00072 19.6 0.1 0.24 11.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 KEY71023.1 - 0.055 13.3 0.1 0.92 9.3 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain p450 PF00067.22 KEY71026.1 - 5.4e-75 252.9 0.0 6.4e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3074 PF11274.8 KEY71027.1 - 6.3e-42 143.6 0.4 9.8e-42 143.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) MbeD_MobD PF04899.12 KEY71028.1 - 0.028 14.5 0.1 0.13 12.4 0.1 2.1 1 0 0 1 1 1 0 MbeD/MobD like TAFII55_N PF04658.13 KEY71029.1 - 4.2e-52 176.1 0.0 4.2e-52 176.1 0.0 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region Kinesin PF00225.23 KEY71031.1 - 5.6e-95 318.1 0.8 6.7e-95 317.8 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEY71031.1 - 1.1e-20 74.1 0.0 2.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 KEY71031.1 - 0.0024 17.7 7.8 0.0042 16.9 0.5 3.5 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TFB6 PF17110.5 KEY71031.1 - 1.7 8.4 5.3 4.4 7.0 4.8 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF724 PF05266.14 KEY71031.1 - 4.8 7.0 8.7 3.5 7.4 3.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Stk19 PF10494.9 KEY71032.1 - 2.8e-60 204.0 0.0 3.4e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.20 KEY71033.1 - 3.6e-52 177.4 14.0 6.4e-52 176.6 14.0 1.4 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KEY71033.1 - 4.2e-16 58.8 0.0 8.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KEY71033.1 - 2.8e-11 43.1 0.0 5.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.11 KEY71034.1 - 3.2e-12 46.9 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KEY71034.1 - 0.055 14.3 0.0 0.44 11.4 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT EF1_GNE PF00736.19 KEY71035.1 - 6.8e-34 115.9 1.8 1.1e-33 115.2 1.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KEY71035.1 - 2.7e-14 53.3 7.1 2.7e-14 53.3 7.1 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KEY71035.1 - 3.7e-05 23.9 0.7 0.00018 21.7 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY71035.1 - 0.00035 20.7 0.1 0.0029 17.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY71035.1 - 0.068 13.2 0.3 0.81 9.8 0.3 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.8 KEY71035.1 - 0.26 11.2 4.8 7.4 6.5 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Proteasom_Rpn13 PF04683.13 KEY71036.1 - 5.1e-27 94.2 0.0 7.8e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KEY71036.1 - 1.5e-09 38.1 0.2 7.3e-09 35.8 0.2 2.0 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 KEY71036.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 L27_2 CTP_synth_N PF06418.14 KEY71037.1 - 9.2e-122 405.4 0.0 1.2e-121 405.0 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KEY71037.1 - 1.1e-49 168.7 0.0 1.7e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEY71037.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.7 2 1 0 2 2 2 1 Peptidase C26 DUF2469 PF10611.9 KEY71037.1 - 0.015 15.8 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) CbiA PF01656.23 KEY71037.1 - 0.062 13.4 0.0 0.074 13.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_1 PF00076.22 KEY71038.1 - 3.5e-14 52.4 0.0 4.1e-07 29.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY71038.1 - 0.05 13.5 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Peptidase_S49_N PF08496.10 KEY71038.1 - 0.16 12.0 0.7 5.7 7.0 0.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal 5-nucleotidase PF06189.12 KEY71040.1 - 0.15 10.9 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 5'-nucleotidase DUF3405 PF11885.8 KEY71041.1 - 1.9e-225 749.4 0.0 2.2e-225 749.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 KEY71042.1 - 9.3e-44 149.5 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1408 PF07193.11 KEY71042.1 - 0.097 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Arf PF00025.21 KEY71043.1 - 2.6e-80 268.0 0.3 3e-80 267.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEY71043.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEY71043.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEY71043.1 - 2.6e-13 49.9 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KEY71043.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEY71043.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY71043.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEY71043.1 - 0.0095 15.3 1.0 0.028 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 KEY71044.1 - 2.8e-44 151.2 0.0 1.7e-43 148.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KEY71044.1 - 1.1e-35 121.7 2.6 1.1e-35 121.7 2.6 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KEY71044.1 - 7.8e-26 89.9 1.4 1.5e-25 89.0 0.1 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KEY71044.1 - 1.2e-18 67.8 0.0 9.9e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY71044.1 - 1.8e-12 47.5 0.1 8.1e-09 35.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEY71044.1 - 3.1e-09 37.5 4.4 0.0014 19.0 0.7 4.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY71044.1 - 2.5e-07 31.1 0.7 0.025 14.8 0.1 3.5 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KEY71044.1 - 1.7e-06 27.9 0.4 0.00057 19.6 0.1 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KEY71044.1 - 8.8e-06 25.8 2.0 0.9 9.4 0.1 4.0 2 2 1 4 4 4 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KEY71044.1 - 7.6e-05 22.7 0.0 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 KEY71044.1 - 0.00018 21.0 0.1 0.042 13.3 0.1 3.4 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 KEY71044.1 - 0.0002 21.0 0.0 0.82 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KEY71044.1 - 0.00047 20.2 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KEY71044.1 - 0.00047 19.9 0.2 0.58 9.9 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KEY71044.1 - 0.0013 19.3 0.0 0.3 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEY71044.1 - 0.0025 18.3 1.1 0.31 11.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter ERM PF00769.19 KEY71044.1 - 0.0028 17.5 6.1 0.0053 16.6 6.1 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_33 PF13671.6 KEY71044.1 - 0.0048 17.1 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEY71044.1 - 0.0048 16.3 0.1 2 7.8 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEY71044.1 - 0.0066 16.8 0.0 1.1 9.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KEY71044.1 - 0.0072 16.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEY71044.1 - 0.011 15.9 0.6 7.1 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KEY71044.1 - 0.013 15.4 1.3 1.4 8.8 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase DUF815 PF05673.13 KEY71044.1 - 0.014 14.5 1.0 0.96 8.6 0.4 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF815) SRP54 PF00448.22 KEY71044.1 - 0.015 15.0 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KEY71044.1 - 0.017 14.8 0.1 0.58 9.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 KEY71044.1 - 0.023 14.7 0.3 9.4 6.2 0.0 3.3 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KEY71044.1 - 0.023 14.3 0.1 0.39 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEY71044.1 - 0.024 14.6 0.1 9.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KEY71044.1 - 0.026 14.7 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KEY71044.1 - 0.027 15.0 5.7 9.6 6.6 3.8 3.3 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 KEY71044.1 - 0.029 13.9 2.7 0.49 9.9 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KEY71044.1 - 0.04 14.3 0.9 0.75 10.1 0.1 3.0 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.9 KEY71044.1 - 0.046 13.5 0.0 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KEY71044.1 - 0.047 13.1 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 KEY71044.1 - 0.066 12.5 0.0 2.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin DUF3782 PF12644.7 KEY71044.1 - 0.13 12.5 1.6 0.66 10.2 1.6 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) OEP PF02321.18 KEY71044.1 - 0.31 10.8 4.5 0.83 9.4 4.5 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein DUF16 PF01519.16 KEY71044.1 - 1.9 9.0 8.9 24 5.5 4.5 3.5 3 1 0 3 3 2 0 Protein of unknown function DUF16 GrpE PF01025.19 KEY71044.1 - 2.2 7.9 8.1 6 6.5 7.1 2.2 2 0 0 2 2 2 0 GrpE DivIC PF04977.15 KEY71044.1 - 3.1 7.6 9.8 7.5 6.4 4.7 2.7 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KEY71044.1 - 3.5 8.2 12.2 10 6.7 12.2 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Prefoldin PF02996.17 KEY71044.1 - 4.3 7.3 8.6 21 5.1 0.3 4.2 4 1 1 5 5 5 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KEY71044.1 - 4.6 7.3 16.9 1.4 9.0 13.0 2.1 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L6e PF01159.19 KEY71045.1 - 2.5e-39 134.2 0.5 2.5e-39 134.2 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 KEY71046.1 - 1.3e-249 829.2 0.0 1.6e-249 828.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SKI PF01202.22 KEY71047.1 - 1.1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KEY71047.1 - 2.1e-10 40.9 0.0 2.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY71047.1 - 1.6e-08 35.2 0.0 3.7e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KEY71047.1 - 6.8e-07 29.2 0.0 7.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 KEY71047.1 - 6.7e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KEY71047.1 - 5.7e-05 23.6 0.0 0.00013 22.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KEY71047.1 - 0.00014 22.3 0.1 0.001 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY71047.1 - 0.0002 21.6 0.0 0.0005 20.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY71047.1 - 0.00046 20.6 0.0 0.00085 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KEY71047.1 - 0.00091 19.1 0.0 0.06 13.2 0.0 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 KEY71047.1 - 0.0023 18.3 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase CoaE PF01121.20 KEY71047.1 - 0.0026 17.4 0.0 0.0073 16.0 0.0 1.8 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_28 PF13521.6 KEY71047.1 - 0.003 17.8 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KEY71047.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family Mg_chelatase PF01078.21 KEY71047.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KEY71047.1 - 0.0086 16.6 0.0 0.027 15.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 KEY71047.1 - 0.0094 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.6 KEY71047.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KEY71047.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KEY71047.1 - 0.017 15.0 0.0 0.042 13.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.9 KEY71047.1 - 0.018 14.3 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 KEY71047.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KEY71047.1 - 0.039 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KEY71047.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEY71047.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KEY71047.1 - 0.052 13.5 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KEY71047.1 - 0.055 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KEY71047.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KEY71047.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_PrkA PF08298.11 KEY71047.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain 2-oxoacid_dh PF00198.23 KEY71048.1 - 8.3e-76 254.5 0.0 1.1e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEY71048.1 - 8.8e-16 57.5 0.0 1.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEY71048.1 - 3e-14 53.0 0.0 7.9e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain ATP-synt_10 PF05176.14 KEY71049.1 - 8.8e-76 254.5 0.0 1.1e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 KEY71050.1 - 8e-13 48.5 8.2 8.2e-13 48.4 0.3 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Atg14 PF10186.9 KEY71050.1 - 0.032 13.3 6.7 0.041 13.0 6.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEY71050.1 - 0.064 12.1 9.9 0.075 11.9 9.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Peptidase_M3_N PF08439.10 KEY71050.1 - 0.44 10.8 3.2 21 5.5 0.0 3.4 3 1 1 4 4 4 0 Oligopeptidase F CHDCT2 PF08074.11 KEY71050.1 - 0.75 9.9 5.5 1 9.5 3.8 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF5082 PF16888.5 KEY71050.1 - 1.1 9.5 7.8 5.7 7.2 5.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF1451 PF07295.11 KEY71050.1 - 7.9 6.5 7.6 9.2 6.3 2.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Ribosomal_L29 PF00831.23 KEY71051.1 - 8.5e-16 57.7 0.8 8.5e-16 57.7 0.8 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein zf-H2C2_2 PF13465.6 KEY71052.1 - 6.2e-14 51.7 39.2 8.9e-06 25.9 1.9 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY71052.1 - 1e-07 32.1 54.6 0.00058 20.5 1.6 8.7 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY71052.1 - 1.7e-07 31.3 62.9 3.6e-05 24.0 2.4 8.4 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KEY71052.1 - 0.034 13.9 0.8 0.034 13.9 0.8 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KEY71052.1 - 0.067 13.1 0.2 0.067 13.1 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KEY71052.1 - 0.12 12.4 0.2 0.12 12.4 0.2 4.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.7 KEY71052.1 - 0.78 10.2 7.8 3.2 8.3 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DEAD PF00270.29 KEY71054.1 - 1.1e-49 168.6 0.0 7.1e-49 165.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71054.1 - 2.7e-27 95.3 0.0 1e-26 93.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HCNGP PF07818.13 KEY71055.1 - 3e-27 95.1 0.0 5.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein INCENP_ARK-bind PF03941.15 KEY71055.1 - 0.55 10.2 2.5 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region DUF3712 PF12505.8 KEY71056.1 - 1.1e-21 77.4 0.4 4.8e-21 75.3 0.0 2.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) FMN_dh PF01070.18 KEY71057.1 - 1.5e-104 349.8 0.0 1.7e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEY71057.1 - 2.9e-19 69.0 0.0 6.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEY71057.1 - 1.9e-07 30.6 0.1 3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY71057.1 - 2.1e-06 27.0 0.3 8.5e-05 21.7 0.0 2.4 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KEY71057.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 KEY71057.1 - 0.02 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 KEY71057.1 - 0.033 13.6 0.4 0.051 13.0 0.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KEY71057.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATP11 PF06644.11 KEY71057.1 - 0.24 11.2 0.0 0.34 10.6 0.0 1.1 1 0 0 1 1 1 0 ATP11 protein HSCB_C PF07743.13 KEY71058.1 - 1.2e-18 67.4 7.9 1.2e-18 67.4 7.9 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KEY71058.1 - 4.5e-06 26.7 0.1 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain DUF1746 PF08508.10 KEY71060.1 - 3.2e-36 124.2 1.9 4.6e-36 123.7 1.9 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.13 KEY71061.1 - 1.7e-30 105.6 0.0 2.9e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KEY71061.1 - 3.3e-30 104.9 0.2 4.2e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PPR_2 PF13041.6 KEY71062.1 - 7.6e-12 45.2 1.5 2.5e-08 34.0 0.0 4.9 6 0 0 6 6 6 1 PPR repeat family PPR_3 PF13812.6 KEY71062.1 - 6.9e-07 29.3 0.0 0.00028 20.9 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_19 PF14559.6 KEY71062.1 - 0.00073 20.0 0.1 1.6 9.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY71062.1 - 0.01 16.4 0.3 26 5.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KEY71062.1 - 0.012 15.3 1.2 14 5.3 0.0 4.0 5 0 0 5 5 5 0 26S proteasome subunit RPN7 PPR_1 PF12854.7 KEY71062.1 - 0.025 14.3 0.3 54 3.6 0.1 4.1 4 0 0 4 4 4 0 PPR repeat PPR_long PF17177.4 KEY71062.1 - 0.029 13.7 0.0 5 6.4 0.0 3.3 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEY71062.1 - 0.032 14.5 7.3 0.22 11.9 0.0 5.2 7 0 0 7 7 7 0 PPR repeat Myb_DNA-bind_6 PF13921.6 KEY71062.1 - 0.12 12.7 0.1 0.35 11.2 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain TPR_7 PF13176.6 KEY71062.1 - 1.9 8.7 4.8 16 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Bromo_TP PF07524.13 KEY71063.1 - 3.2e-09 36.7 0.0 5.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KEY71063.1 - 5.6e-05 23.2 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Cyanate_lyase PF02560.14 KEY71063.1 - 0.21 11.5 0.5 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain NuA4 PF09340.10 KEY71064.1 - 1.5e-23 82.4 0.8 1.9e-23 82.1 0.1 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DHR10 PF18595.1 KEY71064.1 - 0.061 13.4 0.9 0.061 13.4 0.9 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PWI PF01480.17 KEY71065.1 - 8.5e-31 106.1 0.3 1.4e-30 105.4 0.3 1.3 1 0 0 1 1 1 1 PWI domain Nas2_N PF18265.1 KEY71066.1 - 3.4e-31 107.0 0.1 4.8e-31 106.5 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KEY71066.1 - 2.5e-08 33.7 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KEY71066.1 - 1.6e-06 28.4 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KEY71066.1 - 2.1e-06 28.1 0.0 4.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KEY71066.1 - 0.00054 20.3 0.1 0.00084 19.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 KEY71067.1 - 6.3e-49 165.7 0.0 7.8e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY71067.1 - 1.9e-29 102.3 0.0 5e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY71067.1 - 1.4e-10 40.9 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEY71067.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEY71067.1 - 0.0006 20.2 0.1 0.0052 17.1 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KEY71067.1 - 0.0036 16.7 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KEY71067.1 - 0.0051 16.3 0.1 0.0095 15.4 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_7 PF12775.7 KEY71067.1 - 0.015 14.8 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KEY71067.1 - 0.019 14.9 0.1 6 6.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KEY71067.1 - 0.023 13.9 1.5 1.6 7.8 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 KEY71067.1 - 0.035 13.8 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEY71067.1 - 0.065 13.6 0.1 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 KEY71067.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KEY71067.1 - 0.1 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEY71067.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KEY71067.1 - 0.3 10.6 1.0 3.2 7.3 1.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Homeodomain PF00046.29 KEY71068.1 - 1.8e-13 50.1 3.8 2.5e-13 49.7 2.6 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KEY71068.1 - 0.014 15.2 0.2 0.036 14.0 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.21 KEY71069.1 - 3.9e-82 275.7 0.0 5.4e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Fer2_3 PF13085.6 KEY71069.1 - 0.065 13.3 0.0 0.43 10.6 0.0 2.2 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RNase_PH PF01138.21 KEY71071.1 - 5.9e-13 49.5 0.0 1e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEY71071.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 KEY71072.1 - 9.1e-112 373.4 0.0 1.1e-111 373.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carb_kinase PF01256.17 KEY71074.1 - 4.4e-54 183.5 0.0 5.8e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KEY71074.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.25 KEY71075.1 - 3.3e-74 249.1 0.0 5.6e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KEY71075.1 - 2.1e-47 160.6 0.5 3.7e-47 159.8 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KEY71075.1 - 3.5e-15 56.3 2.8 8.6e-15 55.0 2.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 KEY71075.1 - 0.12 12.7 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L5_C PF00673.21 KEY71076.1 - 1.8e-22 79.3 0.0 2.8e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEY71076.1 - 2.7e-20 72.4 0.0 8.2e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KEY71077.1 - 1.9e-16 59.5 0.0 2.6e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Fungal_trans_2 PF11951.8 KEY71078.1 - 1.1e-05 24.4 2.0 0.00057 18.8 0.4 2.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain DnaJ PF00226.31 KEY71079.1 - 2.2e-09 37.3 0.2 3.8e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain PcfK PF14058.6 KEY71079.1 - 0.089 13.1 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 PcfK-like protein Bacteriocin_IIc PF10439.9 KEY71079.1 - 0.74 10.0 7.5 1.4 9.1 7.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 KEY71079.1 - 2.7 7.9 12.2 5.4 7.0 12.2 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Clr5 PF14420.6 KEY71080.1 - 1.7e-11 44.2 0.3 4e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KEY71080.1 - 2.4e-06 27.7 5.8 5.2e-06 26.7 0.9 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY71080.1 - 2.4e-05 24.1 2.6 0.04 14.1 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY71080.1 - 0.00021 21.0 9.1 0.031 14.2 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY71080.1 - 0.0049 16.8 5.2 0.11 12.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY71080.1 - 0.011 16.4 7.9 0.012 16.2 1.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY71080.1 - 0.028 14.9 1.8 0.13 12.8 0.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 KEY71080.1 - 0.031 14.0 0.6 0.054 13.2 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KEY71080.1 - 0.031 15.1 10.9 1.1 10.2 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY71080.1 - 0.05 13.4 0.4 0.26 11.2 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY71080.1 - 0.94 10.3 7.4 2.5 9.0 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY71080.1 - 1.2 9.9 3.5 10 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PITH PF06201.13 KEY71081.1 - 9.2e-37 126.6 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KEY71081.1 - 1.1e-20 73.6 0.0 1.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KEY71081.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY71081.1 - 4.2e-05 23.9 0.1 0.00011 22.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEY71081.1 - 7.3e-05 23.0 0.0 0.00041 20.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KEY71081.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 KEY71081.1 - 0.023 14.7 0.0 0.079 12.9 0.0 1.8 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KEY71081.1 - 0.06 13.2 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.10 KEY71081.1 - 0.09 12.5 0.5 2.2 8.0 0.2 2.3 1 1 1 2 2 2 0 Redoxin BTB PF00651.31 KEY71082.1 - 0.004 17.4 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MTA_R1 PF17226.2 KEY71082.1 - 0.019 15.1 0.1 0.065 13.4 0.1 1.9 1 0 0 1 1 1 0 MTA R1 domain Chaperone_III PF07824.12 KEY71082.1 - 0.031 14.5 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Type III secretion chaperone domain RhoGAP PF00620.27 KEY71084.1 - 1.8e-42 144.7 0.3 4e-42 143.6 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KEY71084.1 - 1.5e-12 47.9 0.0 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PspA_IM30 PF04012.12 KEY71084.1 - 0.0072 15.9 1.2 0.014 15.0 1.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family PH_8 PF15409.6 KEY71084.1 - 0.03 14.6 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain GOLGA2L5 PF15070.6 KEY71084.1 - 0.04 12.6 2.9 0.047 12.4 0.3 2.0 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 PX PF00787.24 KEY71084.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 PX domain Zn_clus PF00172.18 KEY71085.1 - 2.9e-05 24.1 7.5 5.9e-05 23.1 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WLM PF08325.10 KEY71087.1 - 3e-25 89.4 1.4 1.2e-24 87.5 1.4 2.1 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KEY71087.1 - 2e-07 31.2 2.4 4.1e-07 30.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF45 GREB1 PF15782.5 KEY71087.1 - 0.67 7.0 4.8 0.81 6.7 4.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RanBP PF00641.18 KEY71087.1 - 7.9 5.9 12.0 2.5 7.5 3.8 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sulfate_transp PF00916.20 KEY71088.1 - 1.5e-108 363.0 17.2 2e-108 362.5 17.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEY71088.1 - 2.5e-08 33.6 0.0 5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KEY71088.1 - 0.0006 20.2 4.3 0.0006 20.2 4.3 3.4 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily TMEM107 PF14995.6 KEY71088.1 - 0.35 11.3 6.6 0.09 13.2 1.7 2.2 2 0 0 2 2 2 0 Transmembrane protein RabGAP-TBC PF00566.18 KEY71089.1 - 1e-32 113.5 0.0 2.4e-32 112.3 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HlyIII PF03006.20 KEY71090.1 - 1.6e-59 201.4 18.4 1.9e-59 201.1 18.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.11 KEY71090.1 - 0.048 13.8 5.9 0.28 11.3 1.9 3.1 3 1 0 3 3 3 0 Ycf66 protein N-terminus DUF883 PF05957.13 KEY71090.1 - 4.5 7.9 8.0 7.2 7.3 1.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FmiP_Thoc5 PF09766.9 KEY71091.1 - 5.1e-30 105.0 10.9 7e-30 104.5 10.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF2353 PF09789.9 KEY71091.1 - 0.0036 16.7 9.1 0.0052 16.2 9.1 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) SPATA1_C PF15743.5 KEY71091.1 - 0.0045 17.1 4.3 0.0045 17.1 4.3 1.9 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus Flagellin_N PF00669.20 KEY71091.1 - 0.013 15.6 5.0 0.79 9.8 1.2 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Casc1_N PF15927.5 KEY71091.1 - 0.02 14.6 7.4 0.02 14.6 7.4 1.9 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus YfiO PF13525.6 KEY71091.1 - 0.022 14.5 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein DUF1664 PF07889.12 KEY71091.1 - 0.09 12.8 1.3 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KEY71091.1 - 0.2 11.7 10.2 0.3 11.1 10.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SKA2 PF16740.5 KEY71091.1 - 0.26 11.1 8.2 0.06 13.1 1.7 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 KEY71091.1 - 0.38 10.8 13.5 1.3 9.1 7.2 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3958 PF13125.6 KEY71091.1 - 3.8 7.8 16.4 23 5.3 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) DUF87 PF01935.17 KEY71091.1 - 4 7.5 5.5 5.9 6.9 5.5 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain FUSC PF04632.12 KEY71091.1 - 4 5.8 9.3 4.9 5.5 9.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pinin_SDK_memA PF04696.13 KEY71091.1 - 6.1 6.9 15.6 0.5 10.4 9.7 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region MOSC PF03473.17 KEY71092.1 - 1.6e-37 128.5 0.0 2.8e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KEY71092.1 - 4.7e-23 81.3 0.0 1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KEY71092.1 - 7.1e-17 61.4 0.0 9.6e-16 57.7 0.0 2.5 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_trans_2_3 PF13632.6 KEY71093.1 - 4e-17 62.8 0.9 4e-17 62.8 0.9 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DJ-1_PfpI PF01965.24 KEY71094.1 - 3.7e-07 30.1 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family AICARFT_IMPCHas PF01808.18 KEY71095.1 - 2.3e-91 306.3 0.0 3.2e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KEY71095.1 - 1.8e-23 82.5 0.0 3.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Lactamase_B_2 PF12706.7 KEY71095.1 - 0.097 12.2 0.0 9.7 5.6 0.0 2.7 3 0 0 3 3 3 0 Beta-lactamase superfamily domain Pkinase PF00069.25 KEY71096.1 - 3e-40 138.3 0.0 3.3e-31 108.6 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain NPL PF17800.1 KEY71096.1 - 7.9e-33 113.2 6.6 4.4e-32 110.8 6.6 2.4 1 1 0 1 1 1 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KEY71096.1 - 9.1e-31 106.1 0.0 2.6e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.17 KEY71096.1 - 1.9e-16 60.1 0.0 1.8e-15 56.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY71096.1 - 0.073 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KEY71096.1 - 0.45 10.4 3.2 0.53 10.2 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 KEY71097.1 - 4.1e-15 55.9 0.6 9.3e-15 54.8 0.6 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5366 PF17328.2 KEY71097.1 - 0.033 14.3 0.3 0.055 13.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5366) ABM PF03992.16 KEY71098.1 - 1.7e-07 31.3 0.2 0.0019 18.3 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 KEY71098.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain KH_1 PF00013.29 KEY71099.1 - 1.5e-42 143.2 7.4 4.6e-18 64.8 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEY71099.1 - 8.6e-13 47.9 3.0 0.0034 17.2 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEY71099.1 - 7.3e-07 29.0 1.6 0.18 11.7 0.0 3.5 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KEY71099.1 - 2.4e-06 27.4 0.0 0.0031 17.5 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KEY71099.1 - 0.00044 20.3 8.0 0.32 11.1 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain BAF1_ABF1 PF04684.13 KEY71099.1 - 0.057 12.5 2.4 0.077 12.0 2.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CENP-K PF11802.8 KEY71100.1 - 9.8e-09 35.2 0.2 0.0044 16.6 0.0 2.2 2 0 0 2 2 2 2 Centromere-associated protein K Med9 PF07544.13 KEY71100.1 - 0.27 11.3 4.2 9.8 6.3 2.6 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BST2 PF16716.5 KEY71100.1 - 0.28 11.8 8.4 1.1 9.9 2.6 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 KEY71100.1 - 0.43 9.4 11.8 0.54 9.1 4.2 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein M PF02370.16 KEY71100.1 - 1.2 9.9 8.3 4.8 8.1 0.6 3.9 3 0 0 3 3 3 0 M protein repeat Mod_r PF07200.13 KEY71100.1 - 1.7 8.7 14.0 3.3 7.8 2.8 3.4 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Uso1_p115_C PF04871.13 KEY71100.1 - 1.8 8.9 14.1 2.6 8.4 4.6 2.9 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ABC_tran_CTD PF16326.5 KEY71100.1 - 2.3 8.5 12.5 2.4 8.5 1.4 3.7 3 1 0 3 3 3 0 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 KEY71100.1 - 4 7.5 17.7 4.8 7.3 5.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 KEY71100.1 - 8.1 6.0 7.0 2.1 7.9 0.2 2.5 2 1 1 3 3 3 0 fzo-like conserved region Phos_pyr_kin PF08543.12 KEY71101.1 - 4.9e-06 26.1 0.0 0.0007 19.0 0.0 2.2 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase PfkB PF00294.24 KEY71101.1 - 0.013 14.8 0.5 0.17 11.2 0.0 2.8 3 1 0 3 3 3 0 pfkB family carbohydrate kinase PCNA_N PF00705.18 KEY71102.1 - 4e-52 175.2 0.5 7.5e-52 174.4 0.5 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KEY71102.1 - 1.6e-48 164.1 0.0 3.4e-48 163.0 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KEY71102.1 - 2.7e-07 30.3 0.0 3.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KEY71102.1 - 2.4e-05 23.6 0.2 5.5e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KEY71102.1 - 0.00039 19.6 0.0 0.011 14.9 0.0 2.1 1 1 0 2 2 2 1 Hus1-like protein Vezatin PF12632.7 KEY71103.1 - 4.6e-71 239.5 0.0 6.5e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4381 PF14316.6 KEY71103.1 - 0.1 12.8 1.4 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Syntaxin PF00804.25 KEY71103.1 - 0.28 10.8 1.2 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Syntaxin PKcGMP_CC PF16808.5 KEY71105.1 - 0.012 15.4 0.9 0.37 10.7 0.0 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 KEY71105.1 - 0.017 15.2 9.3 0.068 13.3 9.3 2.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 KEY71105.1 - 0.085 11.0 4.5 0.14 10.3 4.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Csm1_N PF18504.1 KEY71105.1 - 0.12 12.8 6.3 3.9 7.9 0.3 3.9 2 1 0 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 KEY71105.1 - 0.57 10.7 11.9 2.1 8.8 2.3 3.9 1 1 2 3 3 3 0 Cell division protein ZapB p450 PF00067.22 KEY71106.1 - 2e-71 241.1 0.0 2.4e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 KEY71107.1 - 5e-09 36.3 5.1 8.2e-09 35.7 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEY71107.1 - 1.1e-06 28.8 3.3 2.2e-06 27.9 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEY71107.1 - 6.5e-05 22.8 3.6 0.0001 22.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY71107.1 - 7.6e-05 22.6 4.0 0.00015 21.8 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEY71107.1 - 0.00014 21.9 0.8 0.00025 21.1 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KEY71107.1 - 0.00019 21.2 7.3 0.00045 20.0 7.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY71107.1 - 0.00093 19.0 4.5 0.0016 18.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY71107.1 - 0.0014 18.4 3.4 0.0026 17.6 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY71107.1 - 0.004 17.0 3.6 0.0071 16.2 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KEY71107.1 - 0.027 14.2 0.2 0.074 12.8 0.2 1.8 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KEY71107.1 - 0.09 12.4 1.1 0.19 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KEY71107.1 - 0.11 12.3 1.1 0.21 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KEY71107.1 - 0.13 12.4 3.6 1.7 8.9 3.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Cullin PF00888.22 KEY71108.1 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KEY71108.1 - 1.2e-20 73.8 0.1 2.9e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-C2H2 PF00096.26 KEY71109.1 - 0.016 15.6 8.8 0.28 11.7 0.6 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KEY71109.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KEY71109.1 - 0.23 12.4 6.1 6.6 7.9 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Pkr1 PF08636.10 KEY71110.1 - 1e-31 108.9 5.8 1.3e-31 108.6 5.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MFS_2 PF13347.6 KEY71111.1 - 1.2e-12 47.2 8.4 1.2e-12 47.2 8.4 1.9 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KEY71111.1 - 1.6e-05 24.0 2.1 4.9e-05 22.4 2.1 1.7 1 0 0 1 1 1 1 MFS_1 like family TMC PF07810.13 KEY71111.1 - 0.13 12.9 1.3 0.4 11.3 0.1 2.3 2 0 0 2 2 2 0 TMC domain DUF1772 PF08592.11 KEY71111.1 - 3.4 8.0 14.0 0.16 12.3 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) PgaD PF13994.6 KEY71111.1 - 7.8 6.5 7.4 4.1 7.5 0.0 2.9 2 1 1 3 3 3 0 PgaD-like protein RhoGEF PF00621.20 KEY71112.1 - 1.2e-30 107.1 0.1 2.6e-30 106.0 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KEY71112.1 - 2.4e-10 40.4 0.2 5.7e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.8 KEY71113.1 - 2.7e-46 157.0 2.6 9.2e-46 155.3 0.6 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KEY71113.1 - 8.2e-14 51.7 0.1 7.4e-10 38.7 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.6 KEY71114.1 - 7.4e-15 55.0 3.5 2e-14 53.6 3.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Zn_clus PF00172.18 KEY71115.1 - 0.00036 20.6 12.0 0.00036 20.6 12.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KEY71117.1 - 7.7e-67 221.3 0.6 1.5e-21 76.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.19 KEY71118.1 - 2.8e-74 250.4 0.0 3.4e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KEY71119.1 - 9.3e-08 31.9 10.2 9.3e-08 31.9 10.2 1.9 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF5643 PF18705.1 KEY71119.1 - 0.3 11.1 1.2 0.65 10.0 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5643) DUF2924 PF11149.8 KEY71119.1 - 0.49 10.8 3.3 0.68 10.3 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) GvpG PF05120.12 KEY71119.1 - 1.2 9.2 14.4 0.033 14.2 2.3 3.0 3 0 0 3 3 3 0 Gas vesicle protein G IMS PF00817.20 KEY71120.1 - 7.6e-41 139.6 0.0 1.6e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KEY71120.1 - 1.2e-22 80.1 0.1 2.8e-22 78.9 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KEY71120.1 - 1e-14 55.3 0.0 2.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KEY71120.1 - 3.7e-14 51.6 11.3 9.1e-07 28.1 2.6 3.8 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 KEY71120.1 - 1.7e-09 37.9 0.0 6.1e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KEY71120.1 - 5.7e-05 23.2 0.0 0.0012 19.0 0.1 2.8 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KEY71120.1 - 0.00024 21.4 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain HHH_5 PF14520.6 KEY71120.1 - 0.00045 20.8 0.1 0.0013 19.3 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.26 KEY71120.1 - 0.00098 19.5 0.0 0.003 17.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 KEY71120.1 - 0.00099 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain MgtE_N PF03448.17 KEY71120.1 - 0.037 14.6 0.9 14 6.3 0.0 3.8 4 0 0 4 4 4 0 MgtE intracellular N domain DUF1805 PF08827.11 KEY71120.1 - 0.18 12.1 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) WSC PF01822.19 KEY71121.1 - 1.9e-17 63.2 9.1 2.4e-17 62.9 9.1 1.1 1 0 0 1 1 1 1 WSC domain SHR3_chaperone PF08229.11 KEY71122.1 - 2e-74 248.7 0.0 2.2e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 KEY71122.1 - 0.039 13.7 0.6 13 5.6 0.0 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) DUF5453 PF17534.2 KEY71122.1 - 0.32 10.9 1.2 1.2 9.1 0.5 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5453) Mito_carr PF00153.27 KEY71123.1 - 3.5e-58 193.5 0.0 3.3e-19 68.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arm-DNA-bind_4 PF14657.6 KEY71123.1 - 0.17 11.7 0.3 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain TspO_MBR PF03073.15 KEY71124.1 - 8.2e-42 142.5 9.0 1.1e-41 142.1 9.0 1.2 1 0 0 1 1 1 1 TspO/MBR family Pam17 PF08566.10 KEY71124.1 - 0.038 13.8 0.2 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 AAA_22 PF13401.6 KEY71125.1 - 2.3e-13 50.6 0.0 6.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY71125.1 - 5.6e-12 46.4 1.1 3.8e-11 43.7 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KEY71125.1 - 6.6e-09 36.3 0.0 2.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KEY71125.1 - 3.5e-06 27.1 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 KEY71125.1 - 6e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Cdc6_C PF09079.11 KEY71125.1 - 7e-06 25.9 0.0 3.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 KEY71125.1 - 7.9e-06 26.3 0.1 6.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEY71125.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KEY71125.1 - 0.0031 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEY71125.1 - 0.0054 16.7 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 KEY71125.1 - 0.0072 15.5 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 KEY71125.1 - 0.0079 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEY71125.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEY71125.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_32 PF13654.6 KEY71125.1 - 0.041 12.7 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY71125.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KEY71125.1 - 0.092 12.5 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEY71125.1 - 0.11 11.6 0.0 0.3 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KEY71125.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KEY71125.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Arrestin_N PF00339.29 KEY71126.1 - 2.4e-13 50.4 0.0 2.7e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEY71126.1 - 1.4e-05 25.6 0.0 0.00017 22.1 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CDC27 PF09507.10 KEY71127.1 - 0.0004 19.9 44.5 0.00055 19.4 44.5 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 G-patch PF01585.23 KEY71127.1 - 0.00053 19.8 0.0 0.0028 17.5 0.0 2.4 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEY71127.1 - 0.73 10.0 0.0 0.73 10.0 0.0 4.3 4 2 0 4 4 4 0 G-patch domain DUF936 PF06075.12 KEY71127.1 - 7.5 5.3 34.1 9.6 5.0 34.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF3546 PF12066.8 KEY71128.1 - 2.2e-31 108.3 5.6 2.2e-31 108.3 5.6 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KEY71128.1 - 1.3e-13 51.7 2.9 6.6e-13 49.5 2.9 2.2 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KEY71128.1 - 1.2e-12 47.4 0.2 2.8e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Glyco_hydro_18 PF00704.28 KEY71129.1 - 4.2e-86 289.5 3.7 5.2e-86 289.2 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADH_zinc_N PF00107.26 KEY71130.1 - 2e-30 105.4 0.9 3e-30 104.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY71130.1 - 1e-10 42.8 0.1 1.9e-10 41.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY71130.1 - 0.00013 21.8 0.0 0.00047 20.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KEY71130.1 - 0.00022 21.5 0.1 0.00042 20.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KEY71130.1 - 0.006 15.9 3.8 0.0078 15.5 3.1 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KEY71130.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ubiquitin PF00240.23 KEY71131.1 - 1.2e-17 63.4 0.1 1.9e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEY71131.1 - 7.3e-07 29.0 0.0 7.3e-07 29.0 0.0 3.1 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.9 KEY71131.1 - 0.0046 17.5 0.1 0.0088 16.6 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KEY71131.1 - 0.0047 16.7 0.2 0.0088 15.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KEY71131.1 - 0.006 16.7 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KEY71131.1 - 0.03 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 KEY71131.1 - 3.3 7.7 13.3 0.13 12.2 7.0 1.9 2 1 0 2 2 2 0 Spore germination GerD central core domain NPR2 PF06218.11 KEY71132.1 - 6.3e-119 397.6 0.0 1.4e-96 324.0 0.0 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 KEY71133.1 - 3.9e-71 239.8 0.0 4.9e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KEY71133.1 - 2.7e-44 149.8 0.0 6.7e-44 148.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain DUF4327 PF14217.6 KEY71133.1 - 0.027 14.6 0.4 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) CybS PF05328.12 KEY71134.1 - 2.5e-49 166.4 0.0 3.1e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF3419 PF11899.8 KEY71135.1 - 2e-164 547.4 0.0 2.6e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KEY71135.1 - 1.5e-12 47.6 0.0 1.3e-10 41.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71135.1 - 1.8e-08 34.9 0.0 3.1e-07 31.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71135.1 - 2.4e-07 30.4 0.1 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEY71135.1 - 3.4e-07 30.9 0.0 1.5e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71135.1 - 7.9e-07 29.6 0.0 2.1e-05 25.0 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71135.1 - 1.9e-06 27.7 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY71135.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KEY71135.1 - 0.043 13.3 0.0 0.28 10.6 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase Ada3 PF10198.9 KEY71136.1 - 1.4e-53 180.5 0.0 1.4e-53 180.5 0.0 2.6 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 RR_TM4-6 PF06459.12 KEY71136.1 - 4.4 7.0 11.5 14 5.4 11.5 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Amidohydro_1 PF01979.20 KEY71137.1 - 1.1e-67 228.9 0.1 2e-67 228.0 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KEY71137.1 - 1.1e-53 180.7 1.8 1.1e-53 180.7 1.8 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KEY71137.1 - 1e-41 140.9 0.1 2.5e-41 139.7 0.1 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KEY71137.1 - 1.2e-35 121.8 0.4 1.9e-21 76.2 0.1 2.6 2 0 0 2 2 2 2 Urease, gamma subunit Amidohydro_3 PF07969.11 KEY71137.1 - 4.8e-08 32.9 0.1 6e-05 22.7 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KEY71137.1 - 0.0056 16.5 0.0 0.056 13.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase HMG_box PF00505.19 KEY71138.1 - 3.6e-06 27.3 0.6 3.6e-06 27.3 0.6 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEY71138.1 - 0.012 16.2 0.2 0.012 16.2 0.2 2.6 3 0 0 3 3 3 0 HMG-box domain Red1 PF07964.11 KEY71138.1 - 1.9 6.6 8.0 2.5 6.3 8.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Het-C PF07217.11 KEY71139.1 - 3.1e-222 739.1 0.0 4e-222 738.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C zf-RING_2 PF13639.6 KEY71140.1 - 1.2e-09 38.3 10.3 2.2e-09 37.5 10.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEY71140.1 - 8.2e-08 31.9 5.6 8.2e-08 31.9 5.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY71140.1 - 1.1e-07 31.6 9.7 2e-07 30.7 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY71140.1 - 4.5e-05 23.2 9.6 8e-05 22.4 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEY71140.1 - 0.00019 21.3 9.5 0.00033 20.6 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KEY71140.1 - 0.00026 21.2 8.4 0.00069 19.9 8.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KEY71140.1 - 0.0013 18.7 9.1 0.0044 17.0 9.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Vps39_2 PF10367.9 KEY71140.1 - 0.021 15.3 0.2 0.021 15.3 0.2 1.8 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 LapA_dom PF06305.11 KEY71140.1 - 0.031 14.1 0.1 0.031 14.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-C3HC4_4 PF15227.6 KEY71140.1 - 0.15 12.2 12.2 0.27 11.4 12.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEY71140.1 - 0.19 11.6 11.8 0.4 10.6 11.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KEY71140.1 - 0.36 10.9 5.6 0.68 10.0 5.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 KEY71140.1 - 0.4 10.4 2.8 32 4.4 0.0 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO Zn_ribbon_17 PF17120.5 KEY71140.1 - 0.89 9.2 9.2 2.8 7.6 9.2 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pex2_Pex12 PF04757.14 KEY71142.1 - 2.4e-38 132.0 1.7 3.1e-38 131.6 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KEY71142.1 - 0.0042 17.2 4.3 0.0095 16.1 4.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KEY71142.1 - 0.012 15.6 0.8 0.038 14.0 0.8 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEY71142.1 - 1.3 8.9 9.1 6.6 6.7 5.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY71142.1 - 5.1 7.5 7.1 9.5 6.6 2.8 2.4 2 1 0 2 2 2 0 Ring finger domain Cytochrom_B558a PF05038.13 KEY71143.1 - 0.069 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.27 KEY71144.1 - 1.9e-16 60.0 0.0 4.5e-16 58.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEY71144.1 - 0.008 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KEY71145.1 - 6.1e-112 374.8 0.0 8e-112 374.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.18 KEY71147.1 - 5.5e-07 28.9 0.9 1.7e-06 27.3 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71147.1 - 3.2e-06 27.1 10.0 3.2e-06 27.1 10.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrgA_MxiK PF09482.10 KEY71147.1 - 0.075 12.9 0.4 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) zf-Tim10_DDP PF02953.15 KEY71148.1 - 1.3e-19 69.6 2.7 1.9e-19 69.1 2.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PG_binding_1 PF01471.18 KEY71149.1 - 0.0011 19.1 0.2 1.7 8.9 0.0 3.0 3 0 0 3 3 3 2 Putative peptidoglycan binding domain FPP PF05911.11 KEY71149.1 - 0.012 13.9 3.8 0.018 13.3 3.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 KEY71149.1 - 0.029 13.0 3.9 0.046 12.4 3.9 1.2 1 0 0 1 1 1 0 AAA domain K-box PF01486.17 KEY71149.1 - 0.056 13.6 0.5 0.15 12.3 0.5 1.7 1 0 0 1 1 1 0 K-box region Sec2p PF06428.11 KEY71149.1 - 0.082 12.9 2.6 0.19 11.7 1.4 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4763 PF15960.5 KEY71149.1 - 0.1 11.9 2.3 0.12 11.7 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Exonuc_VII_L PF02601.15 KEY71149.1 - 0.14 11.7 2.5 0.28 10.7 2.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 KEY71149.1 - 0.16 11.4 5.8 0.14 11.6 3.8 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 KEY71149.1 - 0.29 11.3 3.4 0.36 11.0 1.4 2.1 1 1 0 1 1 1 0 Tropomyosin like FAM184 PF15665.5 KEY71149.1 - 0.68 9.7 5.0 1.6 8.5 5.0 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SlyX PF04102.12 KEY71149.1 - 2.3 8.9 5.7 16 6.2 1.0 2.6 2 0 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.11 KEY71149.1 - 6.1 7.5 6.9 76 4.0 1.9 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CLTH PF10607.9 KEY71150.1 - 1.7e-33 115.6 0.0 2.6e-32 111.8 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KEY71150.1 - 1.1e-06 28.6 0.5 2e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KEY71150.1 - 0.0003 20.2 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KEY71150.1 - 0.0052 16.7 0.4 0.0091 15.9 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEY71150.1 - 0.01 16.1 0.6 0.019 15.3 0.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KEY71150.1 - 0.02 14.7 1.0 0.037 13.9 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEY71150.1 - 0.024 14.5 0.3 0.043 13.7 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RPW8 PF05659.11 KEY71150.1 - 0.099 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ATP-synt_B PF00430.18 KEY71150.1 - 0.13 12.3 2.2 0.28 11.3 0.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4795 PF16043.5 KEY71150.1 - 0.16 11.6 2.1 0.26 10.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-C3HC4_2 PF13923.6 KEY71150.1 - 0.25 11.2 1.0 0.47 10.3 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.27 KEY71151.1 - 1.3e-37 129.4 0.0 3.3e-24 86.0 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY71151.1 - 8.6e-34 117.4 15.8 8.9e-19 68.2 12.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 KEY71151.1 - 1.4e-06 28.8 0.1 0.08 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KEY71151.1 - 1.2e-05 25.4 1.3 0.004 17.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY71151.1 - 1.3e-05 25.2 0.2 0.0046 16.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KEY71151.1 - 2.7e-05 23.6 0.8 0.0044 16.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 KEY71151.1 - 0.00012 22.1 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 KEY71151.1 - 0.00016 21.8 0.6 0.044 13.8 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KEY71151.1 - 0.00021 21.0 0.2 0.067 13.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 KEY71151.1 - 0.00027 21.1 0.1 0.00078 19.6 0.1 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain MeaB PF03308.16 KEY71151.1 - 0.00066 18.7 0.4 0.039 12.9 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KEY71151.1 - 0.00091 19.0 0.5 0.7 9.6 0.1 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEY71151.1 - 0.0012 18.6 1.1 0.29 10.9 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEY71151.1 - 0.0014 19.2 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY71151.1 - 0.0014 18.8 0.9 0.79 9.9 0.5 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY71151.1 - 0.0019 18.8 0.2 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY71151.1 - 0.0033 17.7 1.7 0.73 10.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEY71151.1 - 0.0035 16.9 0.7 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KEY71151.1 - 0.0065 16.0 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEY71151.1 - 0.0072 15.6 0.3 1.7 7.8 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 KEY71151.1 - 0.025 14.2 2.6 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KEY71151.1 - 0.033 13.4 0.8 6 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KEY71151.1 - 0.06 13.6 2.8 1.9 8.7 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEY71151.1 - 0.093 13.2 0.5 3.7 8.0 0.1 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KEY71151.1 - 0.098 12.4 1.9 34 4.1 0.1 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KEY71151.1 - 0.11 12.9 0.1 8.8 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KEY71151.1 - 0.13 11.3 0.1 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.18 KEY71151.1 - 0.17 11.4 0.2 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B SMC_N PF02463.19 KEY71151.1 - 0.17 11.3 0.0 27 4.1 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain KAP_NTPase PF07693.14 KEY71151.1 - 0.17 11.1 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain AIG1 PF04548.16 KEY71151.1 - 0.23 10.7 0.1 0.47 9.8 0.1 1.5 1 0 0 1 1 1 0 AIG1 family TrwB_AAD_bind PF10412.9 KEY71151.1 - 0.33 9.8 3.1 1 8.2 0.1 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 KEY71151.1 - 0.34 11.3 1.1 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEY71151.1 - 0.76 9.5 2.8 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Amidase PF01425.21 KEY71153.1 - 5.6e-54 183.8 0.1 1.8e-53 182.2 0.1 1.7 1 1 0 1 1 1 1 Amidase DUF5577 PF17740.1 KEY71154.1 - 0.012 15.3 2.7 0.018 14.7 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5577) DUF4611 PF15387.6 KEY71154.1 - 2.3 8.5 7.3 0.49 10.6 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KEY71154.1 - 3.7 6.8 8.0 6.2 6.0 8.0 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEY71154.1 - 5.1 7.5 12.1 0.2 12.0 4.7 2.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAS_3 PF08447.12 KEY71155.1 - 8.1e-14 51.7 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KEY71155.1 - 1.3e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KEY71155.1 - 0.0011 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEY71155.1 - 0.0015 18.7 0.1 0.0048 17.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KEY71155.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain AAA_23 PF13476.6 KEY71156.1 - 6.1e-35 121.6 0.1 6.1e-35 121.6 0.1 8.0 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.6 KEY71156.1 - 1.1e-10 41.9 4.7 6.9e-05 22.8 0.6 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY71156.1 - 4.8e-07 29.5 0.0 4.8e-07 29.5 0.0 3.1 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KEY71156.1 - 4.7e-06 26.7 0.0 2.1e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KEY71156.1 - 0.00095 19.0 19.8 0.00095 19.0 19.8 5.5 1 1 2 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY71156.1 - 0.003 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.9 KEY71156.1 - 0.0053 17.0 8.4 0.0053 17.0 8.4 10.0 5 5 4 10 10 10 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_16 PF13191.6 KEY71156.1 - 0.022 15.2 0.0 0.022 15.2 0.0 5.1 4 2 1 5 5 4 0 AAA ATPase domain Surfac_D-trimer PF09006.11 KEY71156.1 - 0.044 13.7 1.3 51 3.9 0.1 4.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation ABC_tran PF00005.27 KEY71156.1 - 0.086 13.4 0.0 0.086 13.4 0.0 7.9 2 1 1 3 3 1 0 ABC transporter AAA_13 PF13166.6 KEY71156.1 - 0.16 10.6 0.0 0.16 10.6 0.0 6.5 2 1 4 7 7 6 0 AAA domain AAA_33 PF13671.6 KEY71156.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEY71156.1 - 0.31 11.3 0.1 0.31 11.3 0.1 4.5 4 1 0 4 4 3 0 AAA domain Methyltransf_25 PF13649.6 KEY71156.1 - 5.3 7.8 7.3 1.7 9.4 0.1 4.1 4 1 1 5 5 3 0 Methyltransferase domain DUF3800 PF12686.7 KEY71156.1 - 6.4 7.4 11.2 1.8e+04 -4.6 10.9 5.3 1 1 0 1 1 0 0 Protein of unknown function (DUF3800) PPP4R2 PF09184.11 KEY71157.1 - 3e-09 36.9 0.0 7.7e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 PPP4R2 SPRY PF00622.28 KEY71157.1 - 7e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.24 KEY71158.1 - 6.8e-39 133.2 39.5 2.8e-21 76.0 20.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YukC PF10140.9 KEY71158.1 - 0.18 10.6 0.0 13 4.5 0.0 2.6 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC DUF872 PF05915.12 KEY71158.1 - 1.1 9.4 6.8 5.1 7.3 0.0 3.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) PBP1_TM PF14812.6 KEY71158.1 - 2 8.9 3.9 3.9 7.9 0.6 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KEY71159.1 - 6.9e-65 219.0 0.0 1.1e-64 218.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71159.1 - 1.2e-35 123.0 0.0 2.1e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY71159.1 - 4.1e-06 26.3 0.1 0.0059 16.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KEY71159.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEY71159.1 - 0.022 13.7 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KEY71159.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEY71159.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GWT1 PF06423.12 KEY71160.1 - 8e-42 142.9 3.4 8.7e-42 142.8 1.8 1.9 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KEY71160.1 - 0.0072 16.8 0.0 0.0072 16.8 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4818) Peroxin-13_N PF04088.13 KEY71160.1 - 0.13 12.6 1.1 6.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region InaF-motif PF15018.6 KEY71160.1 - 0.17 11.8 3.0 0.96 9.4 0.6 2.9 2 0 0 2 2 2 0 TRP-interacting helix Peptidase_S8 PF00082.22 KEY71162.1 - 1.1e-40 139.8 0.0 1.7e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEY71162.1 - 2.7e-13 50.6 0.0 5.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Fungal_trans_2 PF11951.8 KEY71163.1 - 1.4e-44 152.5 0.2 1.8e-44 152.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KEY71164.1 - 1.3e-12 47.3 0.0 2.9e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cyt_bd_oxida_II PF02322.15 KEY71165.1 - 0.0029 17.0 8.0 0.0043 16.5 8.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II EI24 PF07264.11 KEY71165.1 - 0.049 13.9 0.1 0.049 13.9 0.1 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) UPF0182 PF03699.13 KEY71165.1 - 0.064 11.4 3.4 0.076 11.1 3.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) AA_permease PF00324.21 KEY71165.1 - 0.13 10.8 7.0 0.17 10.4 7.0 1.1 1 0 0 1 1 1 0 Amino acid permease DUF4231 PF14015.6 KEY71165.1 - 0.15 12.5 2.4 3.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF373 PF04123.13 KEY71165.1 - 0.2 11.1 4.0 0.27 10.6 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 7TMR-DISM_7TM PF07695.11 KEY71165.1 - 0.41 10.5 13.2 2.1 8.2 13.2 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF973 PF06157.11 KEY71165.1 - 0.95 8.5 6.0 3.4 6.7 6.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF973) ParA PF10609.9 KEY71167.1 - 6.3e-91 304.2 0.1 7.9e-91 303.9 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEY71167.1 - 3.6e-11 43.2 0.0 1.2e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KEY71167.1 - 2.2e-06 27.2 0.1 6.8e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 KEY71167.1 - 7.8e-06 25.3 1.0 0.00013 21.2 0.6 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KEY71167.1 - 1.6e-05 24.9 0.7 9.7e-05 22.3 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KEY71167.1 - 0.00019 21.3 0.4 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KEY71167.1 - 0.00068 19.2 0.0 0.0011 18.5 0.0 1.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KEY71167.1 - 0.0019 17.2 0.5 0.0035 16.4 0.5 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KEY71167.1 - 0.0024 17.5 0.4 0.0058 16.2 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY71167.1 - 0.065 13.6 0.4 0.29 11.5 0.3 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KEY71167.1 - 0.066 12.8 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KEY71167.1 - 0.087 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KEY71167.1 - 0.13 12.2 2.8 0.23 11.4 1.2 2.0 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KEY71167.1 - 0.13 11.5 0.1 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin SAM_decarbox PF01536.16 KEY71168.1 - 7.3e-134 446.3 0.0 9.8e-134 445.8 0.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Metal_resist PF13801.6 KEY71168.1 - 0.036 14.3 0.2 0.069 13.3 0.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Ribosomal_L24e PF01246.20 KEY71169.1 - 6.6e-27 93.5 2.4 6.6e-27 93.5 2.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e KIAA1430 PF13879.6 KEY71169.1 - 0.057 14.2 0.5 0.14 12.9 0.5 1.6 1 0 0 1 1 1 0 KIAA1430 homologue Nop10p PF04135.12 KEY71170.1 - 1.1e-20 73.3 0.1 1.3e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 KEY71171.1 - 3.8e-32 110.2 1.9 6.1e-32 109.6 1.9 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KEY71171.1 - 1.1e-29 102.7 0.1 2.8e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KEY71171.1 - 0.033 13.8 3.5 0.059 13.0 0.8 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KEY71171.1 - 4.7 7.2 5.0 0.61 10.1 0.5 1.9 2 0 0 2 2 2 0 Nudix N-terminal Ferritin_2 PF13668.6 KEY71172.1 - 1.4e-15 57.7 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain DsrC PF04358.13 KEY71172.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 2 0 0 2 2 2 0 DsrC like protein AA_permease_2 PF13520.6 KEY71173.1 - 8.6e-77 258.7 34.7 1e-76 258.5 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY71173.1 - 2.1e-14 53.0 29.9 2.8e-14 52.6 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_31 PF01055.26 KEY71174.1 - 2e-91 307.4 0.0 2.5e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KEY71174.1 - 1e-12 48.2 0.0 2.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like FAD_binding_9 PF08021.11 KEY71174.1 - 0.092 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Aa_trans PF01490.18 KEY71175.1 - 5.8e-50 170.2 26.7 6.6e-50 170.0 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.10 KEY71175.1 - 0.099 12.5 1.3 0.21 11.4 1.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 PPV_E2_C PF00511.17 KEY71175.1 - 0.18 12.0 0.2 0.45 10.7 0.2 1.7 1 0 0 1 1 1 0 E2 (early) protein, C terminal MFS_1 PF07690.16 KEY71176.1 - 3e-37 128.4 43.4 1.1e-36 126.5 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 KEY71176.1 - 0.08 13.1 0.8 0.44 10.7 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DLH PF01738.18 KEY71177.1 - 2.9e-18 66.2 0.7 1.2e-16 60.9 0.7 2.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KEY71177.1 - 0.056 13.4 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DHDPS PF00701.22 KEY71178.1 - 1.8e-29 102.4 0.0 2.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldo_ket_red PF00248.21 KEY71179.1 - 1.2e-49 169.2 0.0 6.5e-49 166.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.26 KEY71180.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY71180.1 - 0.058 14.4 0.0 0.1 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2855 PF11017.8 KEY71180.1 - 0.063 13.0 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Glyco_hydro_47 PF01532.20 KEY71181.1 - 6.8e-166 552.7 0.0 8e-166 552.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KEY71181.1 - 0.061 11.8 0.0 2.8 6.3 0.0 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 adh_short PF00106.25 KEY71183.1 - 1.4e-31 109.5 0.0 6.4e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71183.1 - 1.4e-20 73.8 0.0 1.2e-15 57.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71183.1 - 7.1e-14 52.1 0.0 1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY71183.1 - 0.018 14.9 0.0 0.042 13.7 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding ATP-grasp_5 PF13549.6 KEY71183.1 - 0.027 13.9 0.1 0.095 12.1 0.1 1.7 1 1 1 2 2 2 0 ATP-grasp domain Polysacc_synt_2 PF02719.15 KEY71183.1 - 0.054 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TIR PF01582.20 KEY71183.1 - 0.14 11.9 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 TIR domain Glyco_hydro_61 PF03443.14 KEY71184.1 - 1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_10 PF13460.6 KEY71185.1 - 7e-09 35.8 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY71185.1 - 0.0013 18.4 0.0 0.0033 17.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family APH PF01636.23 KEY71187.1 - 6.5e-16 59.0 0.0 1.1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY71187.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEY71187.1 - 0.061 12.6 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KEY71187.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NAD_binding_4 PF07993.12 KEY71188.1 - 1.6e-40 138.9 0.0 2.3e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEY71188.1 - 7.4e-20 70.9 0.0 1.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KEY71188.1 - 7e-13 48.6 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY71188.1 - 2.9e-05 23.2 0.0 0.00032 19.8 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KEY71188.1 - 3.7e-05 24.0 0.0 9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Zn_clus PF00172.18 KEY71188.1 - 0.013 15.6 3.6 0.024 14.7 3.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GDP_Man_Dehyd PF16363.5 KEY71188.1 - 0.029 13.8 0.0 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KEY71188.1 - 0.12 12.3 0.3 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 KR domain Aldo_ket_red PF00248.21 KEY71189.1 - 1.8e-42 145.5 0.1 9.7e-40 136.6 0.1 2.6 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KEY71190.1 - 1.9e-21 76.3 1.7 3.3e-21 75.5 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_8 PF01501.20 KEY71190.1 - 3e-08 33.5 4.2 1.9e-07 31.0 4.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KEY71190.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Mannosyltransferase putative adh_short_C2 PF13561.6 KEY71191.1 - 2e-61 207.6 1.9 2.5e-61 207.2 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71191.1 - 1.6e-41 142.0 1.8 1.9e-41 141.7 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71191.1 - 1e-05 25.5 0.4 1.5e-05 25.0 0.4 1.2 1 0 0 1 1 1 1 KR domain Dabb PF07876.12 KEY71192.1 - 2.4e-05 24.8 0.1 8.1e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.18 KEY71193.1 - 1.2e-26 93.3 0.0 2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71193.1 - 8.7e-09 35.4 13.8 1.6e-08 34.5 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEY71194.1 - 9.9e-37 126.7 40.7 1.5e-34 119.5 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71194.1 - 2e-11 43.4 7.2 2e-11 43.4 7.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY71194.1 - 2.1e-06 26.4 2.9 3.2e-06 25.9 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amino_oxidase PF01593.24 KEY71195.1 - 4.2e-40 138.4 0.1 8.9e-40 137.3 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY71195.1 - 4.1e-06 26.9 0.0 2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY71195.1 - 0.00028 20.2 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY71195.1 - 0.021 14.1 0.3 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEY71195.1 - 0.16 12.6 0.1 0.39 11.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KEY71196.1 - 7.4e-07 29.4 1.8 4.2e-06 26.9 1.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY71196.1 - 0.00038 20.0 0.1 0.00053 19.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Baculo_PEP_C PF04513.12 KEY71197.1 - 0.014 15.4 4.8 2.4 8.2 0.0 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Staph_haemo PF05480.11 KEY71197.1 - 0.017 14.9 2.0 0.017 14.9 2.0 2.6 3 0 0 3 3 3 0 Staphylococcus haemolytic protein Glyco_hydro_43 PF04616.14 KEY71198.1 - 3e-69 233.5 3.4 4e-69 233.1 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY71198.1 - 1.2e-13 51.3 0.0 1.7e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain MARVEL PF01284.23 KEY71199.1 - 1.5e-06 28.3 12.1 2.6e-06 27.5 7.3 2.1 1 1 1 2 2 2 1 Membrane-associating domain MTABC_N PF16185.5 KEY71199.1 - 0.0087 15.6 0.5 0.081 12.4 0.3 2.2 1 1 1 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region Phage_holin_3_6 PF07332.11 KEY71199.1 - 0.2 11.7 3.6 0.45 10.6 3.6 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 KEY71200.1 - 3.1e-19 69.4 0.0 1.2e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71200.1 - 0.0001 21.7 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Popeye PF04831.13 KEY71201.1 - 0.82 9.8 3.2 1.6 8.9 3.2 1.6 1 0 0 1 1 1 0 Popeye protein conserved region RTA1 PF04479.13 KEY71202.1 - 1.2e-51 175.2 10.0 1.6e-51 174.9 10.0 1.1 1 0 0 1 1 1 1 RTA1 like protein SK_channel PF03530.14 KEY71202.1 - 0.042 13.8 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Calcium-activated SK potassium channel DUF423 PF04241.15 KEY71202.1 - 4.4 7.6 7.7 2.5 8.3 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Fungal_trans_2 PF11951.8 KEY71203.1 - 4.2e-10 39.0 0.1 6.7e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KEY71204.1 - 0.0037 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEY71204.1 - 0.074 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY71204.1 - 0.098 12.6 1.6 0.25 11.2 0.8 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family ADH_N PF08240.12 KEY71205.1 - 8.4e-28 96.4 4.3 1.5e-27 95.6 4.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY71205.1 - 7e-19 68.1 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY71205.1 - 8e-07 30.2 0.0 1.5e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase XdhC_C PF13478.6 KEY71205.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Fungal_lectin PF07938.12 KEY71206.1 - 1.6e-08 34.3 1.6 4.2e-08 32.9 0.0 2.1 2 1 0 2 2 2 1 Fungal fucose-specific lectin Spc7_C2 PF15577.6 KEY71206.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Spc7_C2 Rrn6 PF10214.9 KEY71206.1 - 0.25 9.8 0.4 0.36 9.3 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Atrophin-1 PF03154.15 KEY71206.1 - 0.28 9.4 6.8 0.39 8.9 6.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family NAD_binding_10 PF13460.6 KEY71207.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AcetylCoA_hydro PF02550.15 KEY71208.1 - 1.7e-48 165.2 0.0 2.6e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KEY71208.1 - 1.2e-41 142.3 0.0 1.8e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PALP PF00291.25 KEY71209.1 - 2.1e-40 139.0 0.0 2.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 KEY71209.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 LytB protein Na_Ala_symp PF01235.17 KEY71209.1 - 0.079 12.2 0.0 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 Sodium:alanine symporter family Fungal_trans PF04082.18 KEY71211.1 - 5.2e-06 25.7 0.2 7.3e-05 21.9 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71211.1 - 7.2e-06 26.0 6.2 1.2e-05 25.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliJ PF02050.16 KEY71212.1 - 0.071 13.3 6.1 0.14 12.4 3.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein GAT PF03127.14 KEY71212.1 - 0.072 13.4 1.6 0.43 10.9 1.8 2.1 2 0 0 2 2 2 0 GAT domain KELK PF15796.5 KEY71212.1 - 0.28 11.7 7.6 0.27 11.7 5.7 2.0 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.8 KEY71212.1 - 0.53 10.5 6.3 0.1 12.9 1.6 2.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KEY71212.1 - 1.1 9.6 8.4 15 6.0 1.2 3.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSP70 PF00012.20 KEY71213.1 - 2.7e-08 32.5 0.1 1.5e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY71213.1 - 0.0028 16.5 0.1 0.0089 14.9 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_M20 PF01546.28 KEY71214.1 - 4.4e-18 65.7 0.0 2.7e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY71214.1 - 1.2e-17 63.8 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEY71214.1 - 1.8e-06 27.8 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 GLEYA PF10528.9 KEY71215.1 - 2.5e-17 63.1 0.0 6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 GLEYA domain AdHead_fibreRBD PF16812.5 KEY71215.1 - 0.13 12.1 4.4 0.068 13.0 0.7 2.0 1 1 1 2 2 2 0 C-terminal head domain of the fowl adenovirus type 1 long fibre MFS_1 PF07690.16 KEY71216.1 - 3.1e-29 102.0 29.8 3.1e-29 102.0 29.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Ala_racemase_N PF01168.20 KEY71216.1 - 3.3e-25 89.0 0.2 4.7e-25 88.5 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KEY71216.1 - 3.5e-20 72.5 0.0 9e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain GTP_CH_N PF12471.8 KEY71216.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal RuvX PF03652.15 KEY71216.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Abhydrolase_3 PF07859.13 KEY71217.1 - 8.1e-61 205.6 0.0 1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY71217.1 - 1.6e-07 30.6 0.3 4.5e-07 29.1 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY71217.1 - 4e-05 23.2 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KEY71217.1 - 0.051 12.4 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase adh_short PF00106.25 KEY71218.1 - 9.4e-31 106.8 0.0 5.3e-30 104.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71218.1 - 2.7e-20 72.9 0.0 5.1e-20 72.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71218.1 - 3.8e-07 30.2 0.1 5.5e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY71218.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EamA PF00892.20 KEY71219.1 - 9.3e-26 90.6 34.1 8.5e-13 48.7 9.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 KEY71219.1 - 0.018 14.9 0.2 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5134 PF17197.4 KEY71219.1 - 8.1 6.3 8.8 2.4 8.0 4.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Glyco_hydro_62 PF03664.13 KEY71220.1 - 3.4e-138 459.5 7.7 4.4e-138 459.1 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KEY71220.1 - 1e-11 44.6 19.8 2.4e-11 43.4 19.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEY71220.1 - 0.041 14.1 8.8 0.094 13.0 8.8 1.7 1 1 0 1 1 1 0 Toxin 7 Pectate_lyase PF03211.13 KEY71221.1 - 5.4e-78 261.2 4.8 6.5e-78 260.9 4.8 1.0 1 0 0 1 1 1 1 Pectate lyase Acetyltransf_1 PF00583.25 KEY71223.1 - 1.2e-15 57.7 0.0 3.1e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY71223.1 - 9.4e-15 54.8 0.0 4.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY71223.1 - 1.2e-11 44.8 0.1 2.4e-05 24.4 0.0 3.6 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY71223.1 - 2.1e-09 37.2 0.4 0.00059 19.7 0.0 2.6 2 1 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 KEY71223.1 - 1.5e-08 34.7 0.1 0.0069 16.3 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY71223.1 - 5.2e-06 26.5 0.1 0.06 13.5 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase PanZ PF12568.8 KEY71223.1 - 0.075 12.8 0.3 2.9 7.6 0.1 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KEY71223.1 - 0.12 12.4 0.1 0.92 9.5 0.0 2.5 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase DUF3696 PF12476.8 KEY71224.1 - 0.033 14.6 0.6 0.069 13.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF3135 PF11333.8 KEY71225.1 - 0.069 13.4 0.0 1.2 9.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) DUF676 PF05057.14 KEY71226.1 - 4.4e-05 23.1 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY71226.1 - 0.00013 22.7 0.2 0.00041 21.0 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEY71226.1 - 0.00019 21.3 0.1 0.0018 18.0 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.12 KEY71226.1 - 0.0092 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 KEY71226.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 KEY71226.1 - 0.14 11.8 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY71226.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PCYCGC PF13798.6 KEY71226.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Zn_clus PF00172.18 KEY71227.1 - 1.9e-06 27.8 9.7 2.9e-06 27.3 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY71227.1 - 0.0062 15.4 0.2 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4519 PF15012.6 KEY71228.1 - 0.00092 19.3 1.0 0.0015 18.6 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) GAS PF13851.6 KEY71228.1 - 0.03 13.7 0.7 0.036 13.4 0.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_hydro_61 PF03443.14 KEY71229.1 - 2.5e-53 181.1 0.0 3.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SGL PF08450.12 KEY71230.1 - 3.8e-10 39.8 0.2 6.4e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KEY71230.1 - 0.03 14.5 0.0 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Strictosidine synthase PD40 PF07676.12 KEY71230.1 - 0.12 12.3 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Rep_1B PF17873.1 KEY71230.1 - 1.8 8.5 4.3 4.5 7.2 1.0 3.2 3 0 0 3 3 3 0 Replicase polyprotein 1ab Pec_lyase_C PF00544.19 KEY71231.1 - 3.6e-39 134.5 0.5 5.3e-39 134.0 0.5 1.2 1 0 0 1 1 1 1 Pectate lyase CYYR1 PF10873.8 KEY71232.1 - 0.00086 19.8 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 SKG6 PF08693.10 KEY71232.1 - 0.0089 15.4 0.6 0.028 13.8 0.6 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 KEY71232.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PTP_tm PF18861.1 KEY71232.1 - 0.03 14.3 1.2 0.072 13.1 0.4 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TctA PF01970.16 KEY71232.1 - 0.045 12.5 2.9 0.075 11.7 0.1 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Podoplanin PF05808.11 KEY71232.1 - 0.071 13.2 1.5 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Podoplanin EphA2_TM PF14575.6 KEY71232.1 - 0.15 13.0 0.0 0.36 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2613 PF11021.8 KEY71232.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Gram_pos_anchor PF00746.21 KEY71232.1 - 3.9 7.5 5.8 19 5.3 5.8 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 KEY71233.1 - 1.2e-39 136.2 20.7 1.2e-39 136.2 20.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71233.1 - 2.2e-10 40.0 23.2 3.3e-08 32.9 23.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KEY71233.1 - 2.4e-05 23.8 3.9 2.4e-05 23.8 3.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Peroxidase_2 PF01328.17 KEY71234.1 - 3.4e-50 171.2 0.0 4.5e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Copper-fist PF00649.18 KEY71236.1 - 9.7e-14 50.6 0.6 1.7e-13 49.8 0.6 1.3 1 0 0 1 1 1 1 Copper fist DNA binding domain HET PF06985.11 KEY71237.1 - 1.6e-32 112.9 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 KEY71238.1 - 7.4e-18 64.6 13.9 1.5e-06 28.4 0.6 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KEY71238.1 - 1.1e-13 50.6 8.6 0.0071 16.2 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEY71238.1 - 1.3e-05 24.5 0.4 7.9e-05 22.0 0.4 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_MalT PF17874.1 KEY71238.1 - 1.6e-05 24.5 5.5 0.0061 16.0 5.9 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KEY71238.1 - 0.00092 19.2 2.0 1.3 9.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat UPF0149 PF03695.13 KEY71238.1 - 0.01 16.1 1.3 0.02 15.2 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) TPR_19 PF14559.6 KEY71238.1 - 0.65 10.6 8.1 9 6.9 1.2 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY71238.1 - 0.87 10.6 0.0 0.87 10.6 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY71238.1 - 1.2 9.9 3.1 3e+02 2.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEY71238.1 - 2.4 8.4 6.0 9.3 6.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 KEY71238.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.3 4 0 0 4 4 4 0 HemY protein N-terminus TPR_4 PF07721.14 KEY71238.1 - 4.4 8.2 16.7 18 6.3 0.0 5.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.18 KEY71239.1 - 8.3e-29 100.7 30.0 1.1e-28 100.3 30.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4271 PF14093.6 KEY71239.1 - 0.014 15.3 11.2 0.014 15.3 11.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4271) Oxidored_FMN PF00724.20 KEY71240.1 - 1.1e-63 215.6 0.0 1e-59 202.5 0.0 2.4 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M14 PF00246.24 KEY71241.1 - 2.7e-11 43.8 0.0 5.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_S8 PF00082.22 KEY71241.1 - 6e-06 25.7 0.3 2.6e-05 23.7 0.3 1.9 1 1 0 1 1 1 1 Subtilase family Capsid_N PF16903.5 KEY71241.1 - 0.002 17.8 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Major capsid protein N-terminus AstE_AspA PF04952.14 KEY71241.1 - 0.037 13.1 0.1 0.46 9.5 0.0 2.2 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Abhydrolase_3 PF07859.13 KEY71242.1 - 2.7e-25 89.5 0.0 4.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M28 PF04389.17 KEY71242.1 - 4.7e-23 81.9 0.0 7.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Say1_Mug180 PF10340.9 KEY71242.1 - 6e-10 38.5 0.0 3.2e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_M20 PF01546.28 KEY71242.1 - 4.5e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 COesterase PF00135.28 KEY71242.1 - 0.0034 16.3 0.1 0.019 13.9 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family MFS_1 PF07690.16 KEY71243.1 - 2.5e-41 141.8 23.7 2.5e-41 141.8 23.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71243.1 - 6.9e-12 45.0 6.4 6.9e-12 45.0 6.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KEY71243.1 - 0.00044 18.7 2.4 0.00044 18.7 2.4 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Gly_kinase PF02595.15 KEY71244.1 - 5.6e-123 410.6 3.0 6.4e-123 410.4 3.0 1.0 1 0 0 1 1 1 1 Glycerate kinase family PLA2_B PF01735.18 KEY71245.1 - 4.8e-189 628.8 0.8 5.6e-189 628.6 0.8 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain p450 PF00067.22 KEY71246.1 - 2.1e-56 191.6 0.0 2.7e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 KEY71247.1 - 1.3e-31 109.9 0.0 1.7e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KEY71247.1 - 0.0048 16.7 0.1 0.021 14.6 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KEY71247.1 - 0.0061 17.2 0.3 0.0075 16.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KEY71247.1 - 0.0063 16.1 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_3 PF07859.13 KEY71247.1 - 0.1 12.4 0.5 0.52 10.1 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold DIOX_N PF14226.6 KEY71248.1 - 4.3e-27 95.2 0.0 7.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY71248.1 - 2.8e-21 75.9 0.0 4.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dabb PF07876.12 KEY71249.1 - 4.6e-17 62.4 0.0 5.2e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain NAD_binding_8 PF13450.6 KEY71250.1 - 3.2e-09 36.9 1.2 1.2e-08 35.0 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY71250.1 - 9.2e-08 31.8 0.1 1.4e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY71250.1 - 9.5e-06 24.9 1.2 1.5e-05 24.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY71250.1 - 4.6e-05 22.8 0.0 8.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY71250.1 - 0.00016 20.5 0.5 0.00025 19.9 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KEY71250.1 - 0.0002 21.8 0.3 0.0005 20.6 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY71250.1 - 0.00027 20.4 0.0 0.003 16.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEY71250.1 - 0.003 17.2 1.7 0.0072 15.9 1.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase IlvN PF07991.12 KEY71250.1 - 0.0076 15.8 0.3 0.013 15.0 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 KEY71250.1 - 0.013 14.7 0.6 0.02 14.2 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEY71250.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4945 PF16303.5 KEY71250.1 - 0.038 13.9 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) GIDA PF01134.22 KEY71250.1 - 0.06 12.4 0.4 0.087 11.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KEY71250.1 - 0.064 12.5 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 KEY71251.1 - 8.8e-42 143.3 63.6 1.8e-40 139.0 59.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY71251.1 - 4.9e-22 78.1 11.2 7.3e-22 77.5 11.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEY71251.1 - 1.4e-11 43.9 12.3 1.4e-11 43.9 12.3 3.4 4 0 0 4 4 4 1 Sugar (and other) transporter PIRT PF15099.6 KEY71251.1 - 0.081 12.5 3.0 1.1 8.8 0.2 2.9 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF2109 PF09882.9 KEY71251.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2109) Fungal_trans PF04082.18 KEY71252.1 - 1.7e-18 66.6 0.2 3e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71252.1 - 9.8e-10 38.4 8.8 1.8e-09 37.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.21 KEY71254.1 - 0.025 14.0 0.2 0.05 13.1 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY71254.1 - 0.058 14.0 0.1 0.091 13.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.22 KEY71255.1 - 2.3e-46 158.5 0.0 2.8e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PTR PF12789.7 KEY71255.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage tail repeat like SIR2 PF02146.17 KEY71256.1 - 1.6e-31 109.6 0.3 6.2e-24 84.9 0.0 2.2 1 1 1 2 2 2 2 Sir2 family Glyco_hydro_28 PF00295.17 KEY71257.1 - 1.6e-39 135.9 7.4 8.5e-37 126.9 5.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Adeno_E3_CR2 PF02439.15 KEY71259.1 - 0.0054 16.5 5.3 0.0097 15.6 5.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KEY71259.1 - 0.012 15.5 1.9 0.02 14.8 1.9 1.3 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.6 KEY71259.1 - 0.019 15.2 0.1 0.031 14.5 0.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SLAC1 PF03595.17 KEY71259.1 - 0.027 13.7 0.0 0.031 13.5 0.0 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel RCR PF12273.8 KEY71259.1 - 0.027 15.1 7.4 0.053 14.2 7.4 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 KEY71259.1 - 0.039 13.9 1.6 0.057 13.4 1.6 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Insulin_TMD PF17870.1 KEY71259.1 - 0.041 13.9 1.3 0.067 13.3 1.3 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KEY71259.1 - 0.048 14.5 0.0 0.06 14.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TRP PF06011.12 KEY71259.1 - 0.053 12.3 0.1 0.066 11.9 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PhoD PF09423.10 KEY71260.1 - 7.7e-113 377.1 1.3 1.1e-112 376.6 1.3 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KEY71260.1 - 1.5e-32 112.0 0.2 4e-32 110.6 0.2 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain LOR PF04525.12 KEY71260.1 - 1.3e-23 83.6 0.0 2.4e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 LURP-one-related Pur_ac_phosph_N PF16656.5 KEY71260.1 - 0.045 14.3 2.1 0.047 14.3 0.5 1.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain SSF PF00474.17 KEY71261.1 - 6.5e-24 84.5 29.2 1e-23 83.9 29.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3481 PF11980.8 KEY71261.1 - 1.2 8.9 5.0 0.18 11.5 0.3 2.0 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Peptidase_S8 PF00082.22 KEY71262.1 - 2.5e-40 138.6 0.0 6.5e-40 137.2 0.0 1.6 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEY71262.1 - 6e-17 62.4 0.1 9.8e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Fn3-like domain DUF1735 PF08522.10 KEY71262.1 - 0.055 14.1 0.4 0.12 12.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Peroxidase_2 PF01328.17 KEY71263.1 - 9.8e-39 133.8 0.2 2.2e-38 132.7 0.1 1.6 2 0 0 2 2 2 1 Peroxidase, family 2 Amino_oxidase PF01593.24 KEY71263.1 - 1.8e-17 63.8 0.0 2.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Dynamin_N PF00350.23 KEY71263.1 - 1.3e-06 28.6 0.0 2.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KEY71263.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans_2 PF11951.8 KEY71264.1 - 1e-07 31.1 0.5 1e-07 31.1 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 KEY71265.1 - 4e-58 196.4 3.2 4e-58 196.4 3.2 1.5 1 1 0 1 1 1 1 RTA1 like protein PGG PF13962.6 KEY71265.1 - 0.013 15.3 0.3 0.013 15.3 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function Cyt_c_ox_IV PF12270.8 KEY71265.1 - 0.97 9.6 8.6 0.23 11.6 0.3 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV HET PF06985.11 KEY71266.1 - 1.3e-33 116.4 0.0 2.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KEY71267.1 - 2.4e-10 40.3 8.3 6.3e-10 39.0 8.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.21 KEY71268.1 - 1.4e-46 159.3 0.0 2e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY71268.1 - 1.5e-11 44.7 0.0 5.6e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain TrkH PF02386.16 KEY71269.1 - 5.3e-124 414.4 3.2 7e-121 404.1 1.1 2.0 2 0 0 2 2 2 2 Cation transport protein ABC2_membrane PF01061.24 KEY71271.1 - 1.1e-77 260.2 52.0 9.5e-42 142.8 24.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY71271.1 - 3e-32 112.0 0.0 5.6e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY71271.1 - 8.3e-28 96.1 0.0 8.3e-28 96.1 0.0 3.5 4 0 0 4 4 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KEY71271.1 - 5.7e-14 52.5 0.0 2.3e-13 50.6 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY71271.1 - 1.8e-05 25.2 0.1 0.25 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KEY71271.1 - 5.3e-05 22.9 0.1 0.00027 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY71271.1 - 0.0001 22.2 0.0 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEY71271.1 - 0.0005 19.8 3.0 0.045 13.5 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY71271.1 - 0.00063 19.7 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KEY71271.1 - 0.0007 19.8 0.7 0.072 13.3 0.0 3.4 3 1 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 KEY71271.1 - 0.0012 18.0 44.2 0.088 11.9 15.7 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KEY71271.1 - 0.0032 16.9 0.0 0.14 11.6 0.0 2.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEY71271.1 - 0.017 15.4 0.4 1.9 8.8 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEY71271.1 - 0.021 15.3 0.3 0.68 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KEY71271.1 - 0.04 14.4 0.1 0.39 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEY71271.1 - 0.069 12.9 0.4 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEY71271.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEY71271.1 - 0.078 13.1 0.6 9.2 6.4 0.3 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KEY71271.1 - 0.13 12.7 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KEY71271.1 - 0.14 11.4 0.2 0.94 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KEY71271.1 - 0.17 11.2 0.5 46 3.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.19 KEY71271.1 - 0.64 9.6 3.5 1 8.9 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEY71271.1 - 0.73 9.7 4.6 8.4 6.3 0.2 3.0 3 0 0 3 3 3 0 NACHT domain PDR_assoc PF08370.11 KEY71271.1 - 1.6 8.5 7.9 12 5.8 0.3 3.7 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Fungal_trans PF04082.18 KEY71272.1 - 8.2e-09 34.9 0.7 8.9e-08 31.5 0.7 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71272.1 - 0.5 10.5 3.5 0.87 9.8 3.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KEY71273.1 - 6.1e-56 189.8 0.0 6.9e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Diphthami_syn_2 PF01902.17 KEY71274.1 - 6.9e-23 81.3 0.0 7.6e-16 58.3 0.0 3.2 3 0 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KEY71274.1 - 3.6e-11 43.1 0.0 5.5e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 KEY71275.1 - 4.3e-13 48.9 13.4 5.2e-07 29.8 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY71275.1 - 3.4e-08 33.5 13.8 1e-06 28.9 6.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY71275.1 - 1.9e-07 31.3 12.0 0.003 18.3 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KEY71275.1 - 1.7e-06 28.2 4.9 0.0001 22.6 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEY71275.1 - 2.8e-05 24.3 5.7 0.0014 18.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KEY71275.1 - 0.026 14.2 5.1 1.1 8.9 0.5 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 KEY71275.1 - 0.033 14.2 10.7 0.31 11.1 1.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KEY71275.1 - 0.042 14.5 2.0 3.9 8.2 0.3 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 KEY71275.1 - 0.13 12.2 3.0 0.63 10.0 0.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KEY71275.1 - 0.2 11.3 2.7 5.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KEY71275.1 - 0.94 9.6 6.5 0.42 10.7 2.2 2.2 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KEY71275.1 - 1.1 9.4 5.3 6.8 6.9 0.6 2.8 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KEY71275.1 - 1.3 8.8 7.0 14 5.6 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-UBR PF02207.20 KEY71275.1 - 2.9 8.1 6.0 0.28 11.4 1.2 1.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C2HE PF16278.5 KEY71275.1 - 5.1 7.6 7.6 82 3.8 7.6 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger GspH PF12019.8 KEY71276.1 - 0.032 14.7 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Type II transport protein GspH Glyco_hydro_16 PF00722.21 KEY71277.1 - 3.2e-42 144.0 1.4 5.3e-42 143.3 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 KEY71278.1 - 1.1e-96 322.5 8.5 1.1e-96 322.5 8.5 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KEY71278.1 - 4.7e-95 317.1 4.6 4.7e-95 317.1 4.6 3.7 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KEY71278.1 - 9.8e-32 108.7 0.2 4.7e-31 106.5 0.2 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 KEY71279.1 - 6.6e-81 272.1 2.8 8e-81 271.8 2.8 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.24 KEY71280.1 - 2.5e-84 284.2 0.2 3.4e-70 237.6 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KEY71280.1 - 2.8e-13 50.0 0.1 8.4e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 KEY71280.1 - 4.8e-08 33.1 0.0 1.4e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 KEY71280.1 - 1.3e-05 25.7 5.2 3e-05 24.5 5.2 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KEY71280.1 - 3.5e-05 24.1 3.3 3.5e-05 24.1 3.3 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 KEY71280.1 - 0.0003 20.5 0.1 0.00074 19.2 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY71280.1 - 0.016 14.4 0.0 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sec1 PF00995.23 KEY71281.1 - 3.1e-122 409.7 0.1 3.5e-122 409.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Mrpl_C PF18502.1 KEY71281.1 - 0.039 14.2 0.4 0.61 10.4 0.8 2.5 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Transposase_22 PF02994.14 KEY71281.1 - 0.071 13.3 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 L1 transposable element RBD-like domain UQ_con PF00179.26 KEY71282.1 - 6.2e-26 90.7 0.0 7.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY71282.1 - 1.2e-06 28.3 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEY71282.1 - 0.00047 20.0 0.1 0.00066 19.5 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KEY71282.1 - 0.0015 18.8 0.1 0.0026 18.0 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_A PF14457.6 KEY71282.1 - 0.027 14.1 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family A Pkinase PF00069.25 KEY71284.1 - 5.2e-68 229.3 0.0 7e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71284.1 - 5.3e-33 114.4 0.0 9e-33 113.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71284.1 - 3.2e-06 26.7 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY71284.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KEY71284.1 - 0.038 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ABC_membrane PF00664.23 KEY71286.1 - 1.4e-88 297.1 38.5 6.8e-48 163.7 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY71286.1 - 4.1e-65 218.4 0.2 4.2e-33 114.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY71286.1 - 2.8e-12 46.6 11.2 0.00026 20.5 0.5 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KEY71286.1 - 2.2e-08 34.2 0.5 0.0024 17.6 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEY71286.1 - 8.4e-08 32.6 0.9 0.045 14.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEY71286.1 - 9.5e-08 32.1 0.0 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEY71286.1 - 1.2e-07 32.3 0.7 0.032 14.6 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KEY71286.1 - 3e-07 29.6 1.1 0.12 11.2 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KEY71286.1 - 1.1e-06 28.3 1.1 0.001 18.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY71286.1 - 1e-05 25.5 0.0 0.19 11.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEY71286.1 - 7.9e-05 22.5 6.6 0.075 12.7 0.1 3.4 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.6 KEY71286.1 - 0.00038 20.5 0.4 0.17 11.9 0.1 3.4 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 KEY71286.1 - 0.00075 19.5 0.0 2.9 7.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEY71286.1 - 0.0011 18.6 0.7 1.9 8.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KEY71286.1 - 0.0012 18.4 0.1 1.8 8.0 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KEY71286.1 - 0.0022 17.7 0.6 1.7 8.2 0.0 2.8 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KEY71286.1 - 0.003 18.0 7.4 7.5 7.0 0.2 5.3 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEY71286.1 - 0.0033 18.0 0.0 3.3 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KEY71286.1 - 0.0042 17.0 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 KEY71286.1 - 0.0073 16.5 2.0 2.4 8.5 0.3 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 KEY71286.1 - 0.0097 15.0 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) PRK PF00485.18 KEY71286.1 - 0.01 15.6 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KEY71286.1 - 0.012 15.9 0.0 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEY71286.1 - 0.012 15.4 0.4 3 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEY71286.1 - 0.019 15.5 0.3 0.019 15.5 0.3 3.4 2 1 1 3 3 2 0 AAA domain NB-ARC PF00931.22 KEY71286.1 - 0.023 13.9 0.1 3.1 6.9 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 KEY71286.1 - 0.026 14.7 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEY71286.1 - 0.061 13.2 0.4 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KEY71286.1 - 0.073 13.2 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain SRP54 PF00448.22 KEY71286.1 - 0.074 12.7 0.1 28 4.3 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KEY71286.1 - 0.089 12.1 0.1 5.7 6.2 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin DoxX PF07681.12 KEY71286.1 - 0.2 12.3 0.1 0.2 12.3 0.1 2.9 3 0 0 3 3 1 0 DoxX DUF4710 PF15828.5 KEY71286.1 - 1.5 9.0 5.1 3.9 7.7 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF2852 PF11014.8 KEY71286.1 - 1.9 8.6 4.1 6.4 7.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Vma12 PF11712.8 KEY71286.1 - 6.5 6.8 7.0 0.45 10.6 0.2 2.5 2 1 0 2 2 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Hydrolase_4 PF12146.8 KEY71287.1 - 4.3e-13 49.1 0.0 1.1e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY71287.1 - 2.1e-11 44.9 4.7 2.1e-11 44.9 4.7 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY71287.1 - 2.1e-11 44.0 0.4 3.9e-11 43.1 0.4 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KEY71287.1 - 0.06 13.3 0.0 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Glyco_transf_4 PF13439.6 KEY71287.1 - 0.079 13.0 0.1 5.6 6.9 0.0 2.9 2 1 1 3 3 3 0 Glycosyltransferase Family 4 DLH PF01738.18 KEY71287.1 - 0.088 12.4 0.0 0.98 8.9 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 KEY71287.1 - 0.19 11.8 0.4 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain AIRC PF00731.20 KEY71288.1 - 2.7e-60 202.2 0.4 6.2e-60 201.1 0.4 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KEY71288.1 - 9.5e-48 162.0 0.0 1.6e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KEY71288.1 - 1.6e-14 53.3 0.1 3.7e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KEY71288.1 - 9.4e-08 31.8 0.0 2.5e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KEY71288.1 - 1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.6 KEY71288.1 - 0.026 15.0 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KEY71288.1 - 0.031 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 KEY71288.1 - 0.058 13.0 0.1 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Propionate catabolism activator NAD_binding_10 PF13460.6 KEY71288.1 - 0.093 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H-binding FYVE PF01363.21 KEY71289.1 - 7.3e-21 74.1 0.3 7.3e-21 74.1 0.3 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KEY71289.1 - 4.8e-07 30.0 4.9 4.8e-07 30.0 4.9 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KEY71289.1 - 0.00012 21.7 5.0 0.00012 21.7 5.0 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEY71289.1 - 0.00029 20.6 3.7 0.00029 20.6 3.7 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KEY71289.1 - 0.0012 19.1 2.7 0.0012 19.1 2.7 2.7 2 0 0 2 2 2 1 RING-like domain Rad50_zn_hook PF04423.14 KEY71289.1 - 0.0097 15.7 1.5 0.084 12.7 0.3 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif FYVE_2 PF02318.16 KEY71289.1 - 0.023 14.9 2.5 0.023 14.9 2.5 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger zf-piccolo PF05715.13 KEY71289.1 - 0.17 12.0 15.7 0.11 12.6 5.9 2.9 3 0 0 3 3 3 0 Piccolo Zn-finger DZR PF12773.7 KEY71289.1 - 0.53 10.4 8.3 4.3 7.4 4.8 2.8 2 0 0 2 2 2 0 Double zinc ribbon C2 PF00168.30 KEY71290.1 - 2.4e-85 281.5 0.0 4e-22 78.4 0.0 5.4 5 0 0 5 5 5 5 C2 domain MLVIN_C PF18697.1 KEY71290.1 - 0.021 14.9 0.6 0.14 12.3 0.0 2.6 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Proteasome PF00227.26 KEY71291.1 - 3e-46 157.3 0.2 3.6e-46 157.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Aminotran_1_2 PF00155.21 KEY71292.1 - 2.6e-30 105.8 0.0 3.9e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY71292.1 - 0.0025 16.4 0.0 0.0052 15.4 0.0 1.4 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEY71292.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase BATS PF06968.13 KEY71293.1 - 0.00086 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Abhydrolase_2 PF02230.16 KEY71294.1 - 1e-18 67.9 0.0 1.9e-16 60.5 0.0 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase adh_short PF00106.25 KEY71295.1 - 1.2e-35 122.8 0.0 1.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71295.1 - 1.2e-26 93.8 0.0 2.2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71295.1 - 2.2e-09 37.5 0.1 5.4e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEY71295.1 - 7.8e-05 22.3 0.0 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY71295.1 - 0.00032 20.7 0.1 0.033 14.1 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding DUF1776 PF08643.10 KEY71295.1 - 0.00061 19.2 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 KEY71295.1 - 0.0031 16.7 0.0 0.0074 15.4 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain DUF3425 PF11905.8 KEY71296.1 - 9.6e-22 77.3 0.0 2.1e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KEY71296.1 - 0.004 17.2 5.9 0.004 17.2 5.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KEY71296.1 - 0.07 13.2 7.7 0.13 12.4 7.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short_C2 PF13561.6 KEY71298.1 - 3.7e-30 105.2 0.0 3.2e-29 102.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71298.1 - 1e-22 80.5 0.2 7.6e-22 77.7 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71298.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Enoyl_reductase PF12241.8 KEY71298.1 - 0.043 13.1 0.0 0.074 12.4 0.0 1.3 1 1 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region MFS_1 PF07690.16 KEY71299.1 - 2.2e-22 79.5 47.8 1e-11 44.4 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_rhamnosid6H PF17389.2 KEY71300.1 - 1.7e-115 385.9 0.0 2.4e-115 385.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KEY71300.1 - 5.7e-47 159.7 0.1 1e-46 158.9 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KEY71300.1 - 1.6e-24 85.9 0.0 2.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KEY71300.1 - 8.2e-18 64.0 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain SIX1_SD PF16878.5 KEY71300.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain Zn_clus PF00172.18 KEY71302.1 - 6.3e-08 32.6 8.1 2e-07 31.0 8.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEY71303.1 - 9.1e-74 248.9 17.7 1.1e-73 248.7 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71303.1 - 1.6e-19 70.1 30.1 3.5e-12 45.9 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY71303.1 - 0.0033 16.3 3.2 0.018 13.9 1.3 2.4 2 1 0 2 2 2 1 MFS_1 like family zf-RNPHF PF08080.12 KEY71303.1 - 0.27 11.2 1.0 24 5.0 0.1 2.6 2 0 0 2 2 2 0 RNPHF zinc finger CDH-cyt PF16010.5 KEY71304.1 - 1.4e-52 178.1 2.2 2.3e-52 177.4 0.3 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KEY71304.1 - 4.7e-26 91.9 0.0 9.3e-26 90.9 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY71304.1 - 2.4e-23 83.3 1.1 7.2e-23 81.7 1.1 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY71304.1 - 1.6e-06 27.5 1.2 1e-05 24.9 1.2 2.2 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEY71304.1 - 8.4e-05 21.4 0.3 0.00045 19.0 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KEY71304.1 - 0.003 16.7 0.1 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY71304.1 - 0.004 16.8 0.1 0.076 12.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY71304.1 - 0.0045 16.3 0.6 0.023 13.9 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY71304.1 - 0.0054 16.9 1.0 0.019 15.2 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KEY71304.1 - 0.023 14.3 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KEY71304.1 - 0.024 13.9 0.1 0.15 11.3 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY71304.1 - 0.025 13.8 0.2 0.053 12.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DOMON PF03351.17 KEY71304.1 - 0.07 13.3 0.2 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 DOMON domain Kinesin PF00225.23 KEY71305.1 - 5.1e-50 170.3 0.0 2.5e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KEY71305.1 - 2.9e-10 40.3 0.0 5.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Snapin_Pallidin PF14712.6 KEY71305.1 - 0.069 13.6 0.8 0.14 12.6 0.8 1.4 1 0 0 1 1 1 0 Snapin/Pallidin FAD-oxidase_C PF02913.19 KEY71305.1 - 0.086 12.5 0.7 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Laminin_II PF06009.12 KEY71305.1 - 0.44 10.6 3.7 5.1 7.1 3.5 2.2 1 1 0 1 1 1 0 Laminin Domain II HATPase_c PF02518.26 KEY71306.1 - 2.5e-19 69.8 0.1 5.7e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY71306.1 - 5.3e-18 65.2 0.2 1.5e-17 63.8 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY71306.1 - 3.3e-13 49.5 0.2 8.2e-13 48.2 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FAD_binding_8 PF08022.12 KEY71307.1 - 0.069 13.2 0.4 9.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-binding domain Glyco_hydro_11 PF00457.17 KEY71309.1 - 1.3e-48 164.9 2.7 1.5e-48 164.7 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CFEM PF05730.11 KEY71310.1 - 6.7e-08 32.5 6.5 1e-07 31.9 6.5 1.3 1 0 0 1 1 1 1 CFEM domain adh_short_C2 PF13561.6 KEY71311.1 - 2.4e-62 210.6 1.7 2.8e-62 210.4 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71311.1 - 7.9e-41 139.7 1.3 9.4e-41 139.4 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71311.1 - 1.4e-13 51.2 0.4 2.1e-13 50.6 0.4 1.2 1 0 0 1 1 1 1 KR domain SurE PF01975.17 KEY71312.1 - 1.2e-40 139.4 0.0 1.8e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Sulfatase PF00884.23 KEY71313.1 - 8.9e-51 173.1 0.0 1.1e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEY71313.1 - 0.084 12.5 0.0 5.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Methyltransf_23 PF13489.6 KEY71314.1 - 5e-20 72.0 0.0 7.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71314.1 - 3.4e-13 50.1 0.0 8.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71314.1 - 1.1e-11 45.3 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71314.1 - 4.4e-09 37.0 0.0 1.8e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71314.1 - 6.9e-07 29.2 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71314.1 - 6.8e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEY71314.1 - 0.00055 19.5 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEY71314.1 - 0.0029 17.0 0.0 0.0062 16.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEY71314.1 - 0.0059 16.3 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KEY71314.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KEY71314.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KEY71314.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEY71314.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain adh_short PF00106.25 KEY71315.1 - 1.4e-13 50.8 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71315.1 - 1.5e-09 38.0 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY71315.1 - 5.3e-08 32.7 0.0 8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KEY71315.1 - 0.064 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein OrsD PF12013.8 KEY71316.1 - 1.5e-28 99.6 1.0 2.8e-28 98.6 1.0 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fungal_trans_2 PF11951.8 KEY71316.1 - 5.1e-07 28.8 0.3 9.1e-07 28.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY71317.1 - 4.4e-24 85.1 52.2 6.2e-15 55.0 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase PF00710.20 KEY71318.1 - 1.9e-47 161.3 0.1 2.8e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEY71318.1 - 3e-14 53.2 0.0 9.4e-13 48.4 0.0 2.6 3 0 0 3 3 3 1 Glutaminase/Asparaginase C-terminal domain Acyl_transf_3 PF01757.22 KEY71319.1 - 4.8e-27 94.9 24.5 7.7e-27 94.2 24.5 1.4 1 1 0 1 1 1 1 Acyltransferase family Peptidase_M35 PF02102.15 KEY71321.1 - 9.1e-78 261.6 13.3 1.2e-77 261.3 13.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KEY71321.1 - 1.4e-39 135.9 6.2 2.6e-39 135.1 6.2 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 KEY71321.1 - 0.071 13.4 0.3 0.35 11.1 0.3 2.0 1 1 0 1 1 1 0 CARDB Exo_endo_phos PF03372.23 KEY71322.1 - 2.5e-12 46.8 0.5 5.2e-12 45.8 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KEY71322.1 - 0.011 15.5 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase He_PIG PF05345.12 KEY71322.1 - 0.032 14.4 1.2 0.12 12.6 1.0 2.2 1 1 0 1 1 1 0 Putative Ig domain FAD_binding_3 PF01494.19 KEY71323.1 - 9.6e-35 120.4 0.0 1.4e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY71323.1 - 2e-06 27.3 0.0 4.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY71323.1 - 4.4e-06 26.8 0.3 1.1e-05 25.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY71323.1 - 7.5e-06 25.3 0.8 7.5e-06 25.3 0.8 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY71323.1 - 5.8e-05 22.5 0.2 0.00017 20.9 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY71323.1 - 0.00012 21.0 0.2 0.00028 19.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEY71323.1 - 0.00018 21.0 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEY71323.1 - 0.00045 19.6 0.3 0.089 12.1 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KEY71323.1 - 0.0014 17.7 0.5 0.13 11.3 0.4 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEY71323.1 - 0.0064 16.1 0.5 0.013 15.1 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY71323.1 - 0.0065 15.7 0.2 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KEY71323.1 - 0.013 16.1 0.2 0.036 14.6 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY71323.1 - 0.039 13.0 0.1 0.081 12.0 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KEY71323.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KEY71323.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RTA1 PF04479.13 KEY71324.1 - 4.1e-66 222.5 13.1 4.1e-66 222.5 13.1 1.3 2 0 0 2 2 2 1 RTA1 like protein Kei1 PF08552.11 KEY71324.1 - 0.0039 17.1 2.7 0.0076 16.1 0.1 2.4 2 1 1 3 3 3 1 Inositolphosphorylceramide synthase subunit Kei1 PspB PF06667.12 KEY71324.1 - 0.054 13.6 0.2 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B stn_TNFRSF12A PF12191.8 KEY71324.1 - 0.1 12.8 0.4 0.25 11.6 0.3 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Zn_clus PF00172.18 KEY71325.1 - 9.6e-06 25.6 7.9 1.6e-05 24.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY71325.1 - 0.0021 16.9 0.2 0.0037 16.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 KEY71326.1 - 4.7e-57 193.5 4.8 5.6e-57 193.2 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 KEY71326.1 - 2.8e-15 56.5 0.0 5.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain GMC_oxred_N PF00732.19 KEY71327.1 - 2.1e-42 145.5 0.0 2.9e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY71327.1 - 4.9e-23 82.2 0.0 8.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KEY71327.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KEY71327.1 - 0.019 14.5 0.7 0.68 9.5 0.2 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEY71327.1 - 0.053 13.8 0.2 0.17 12.1 0.2 1.9 1 0 0 1 1 1 0 TrkA-N domain GATA PF00320.27 KEY71328.1 - 9.5e-10 37.9 3.1 1.6e-09 37.2 3.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Methyltransf_23 PF13489.6 KEY71329.1 - 5.5e-16 58.8 0.0 7.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71329.1 - 2.6e-15 56.9 0.0 4.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71329.1 - 3.5e-13 50.1 0.0 1.5e-12 48.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71329.1 - 6.1e-13 49.2 0.0 1.6e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71329.1 - 1.4e-11 44.4 0.0 1.8e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71329.1 - 0.0018 17.7 0.0 0.021 14.2 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEY71329.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KEY71329.1 - 0.055 12.4 0.0 0.18 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 KEY71329.1 - 0.092 12.2 0.0 2.6 7.5 0.0 2.6 2 1 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.20 KEY71329.1 - 0.095 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 KEY71329.1 - 0.12 12.0 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) PrmA PF06325.13 KEY71329.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BCS1_N PF08740.11 KEY71330.1 - 5.7e-34 117.7 1.2 9.6e-34 117.0 0.8 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KEY71330.1 - 1e-23 84.2 0.0 1.7e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEY71330.1 - 3e-05 23.8 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEY71330.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 KEY71330.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KEY71330.1 - 0.023 14.7 0.0 0.1 12.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEY71330.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEY71330.1 - 0.067 13.6 0.1 7.2 7.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEY71330.1 - 0.079 13.3 0.1 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.13 KEY71330.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain MFS_1 PF07690.16 KEY71331.1 - 2e-24 86.2 20.9 2e-24 86.2 20.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 KEY71332.1 - 1.5e-15 57.4 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KEY71332.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ThiJ_like PF17124.5 KEY71332.1 - 0.091 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like FAD_binding_6 PF00970.24 KEY71333.1 - 3.2e-14 53.1 0.0 5.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KEY71333.1 - 3.2e-14 52.8 0.0 6.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 KEY71333.1 - 2.1e-08 34.8 0.0 1.8e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AAA_19 PF13245.6 KEY71333.1 - 0.17 12.2 0.4 0.31 11.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain COesterase PF00135.28 KEY71334.1 - 5.2e-87 292.9 0.0 7.6e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY71334.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1965 PF09248.10 KEY71334.1 - 0.0063 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.20 KEY71334.1 - 0.052 12.5 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Esterase_phd PF10503.9 KEY71335.1 - 4.6e-23 81.9 0.8 7.4e-23 81.2 0.8 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KEY71335.1 - 1.1e-12 47.6 7.8 1.1e-12 47.6 7.8 2.6 3 1 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KEY71335.1 - 3.4e-09 36.5 1.1 5.1e-09 35.9 1.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEY71335.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEY71335.1 - 0.016 15.0 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KEY71335.1 - 0.072 13.0 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glycoprotein PF03409.15 KEY71335.1 - 1.4 7.7 9.0 2.4 6.9 9.0 1.3 1 0 0 1 1 1 0 Transmembrane glycoprotein adh_short_C2 PF13561.6 KEY71336.1 - 2.8e-51 174.4 0.0 3.7e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71336.1 - 3.1e-45 154.0 0.0 3.8e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71336.1 - 3e-08 33.8 0.1 4.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEY71336.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEY71336.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family WVELL PF14043.6 KEY71336.1 - 0.057 13.3 0.4 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 WVELL protein 3HCDH_N PF02737.18 KEY71336.1 - 0.094 12.6 0.0 2.2 8.1 0.0 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.24 KEY71337.1 - 2.5e-34 118.6 0.0 3.3e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_61 PF03443.14 KEY71338.1 - 4.6e-34 118.2 0.0 5.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short_C2 PF13561.6 KEY71339.1 - 6e-35 120.9 0.3 1.6e-21 77.0 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71339.1 - 1.2e-32 112.9 3.8 1.1e-19 70.6 0.5 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY71339.1 - 7.5e-09 35.8 1.2 7.5e-09 35.8 1.2 2.7 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KEY71339.1 - 0.033 14.1 0.4 0.061 13.2 0.1 1.5 2 0 0 2 2 2 0 NAD(P)H-binding PAD_porph PF04371.15 KEY71339.1 - 0.061 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase 3Beta_HSD PF01073.19 KEY71339.1 - 0.068 12.2 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ChapFlgA_N PF17656.1 KEY71339.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 FlgA N-terminal domain UbiA PF01040.18 KEY71340.1 - 7.3e-32 110.6 13.7 7.3e-32 110.6 13.7 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family AMP-binding PF00501.28 KEY71341.1 - 1.4e-35 122.7 0.0 2.3e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KEY71341.1 - 1.8e-17 63.3 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KEY71341.1 - 3.8e-06 27.2 0.1 1.8e-05 25.0 0.1 2.3 2 1 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 KEY71341.1 - 5.1e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KEY71342.1 - 1.4e-72 244.4 7.0 1.4e-72 244.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY71342.1 - 3.1e-31 107.8 2.0 3.3e-31 107.8 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEY71342.1 - 3.1e-20 72.3 6.2 1.2e-10 41.6 0.6 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KEY71342.1 - 2.4e-19 69.7 0.0 1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY71342.1 - 1.6e-17 64.0 0.2 1.1e-15 57.9 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KEY71342.1 - 4.6e-13 49.6 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_3 PF07859.13 KEY71342.1 - 6.1e-13 49.1 0.0 2.3e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold SAT PF16073.5 KEY71342.1 - 3.1e-09 36.9 13.9 5.3e-09 36.2 0.1 3.6 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KEY71342.1 - 7.7e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Peptidase_S9 PF00326.21 KEY71342.1 - 0.00038 20.0 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 KEY71342.1 - 0.0066 16.6 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Zn_clus PF00172.18 KEY71343.1 - 8.1e-09 35.5 7.8 8.1e-09 35.5 7.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KEY71343.1 - 0.28 11.0 6.2 0.64 9.8 2.0 2.4 2 0 0 2 2 2 0 Integrin plexin domain DDE_Tnp_1_7 PF13843.6 KEY71344.1 - 1.4e-16 60.8 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 HET PF06985.11 KEY71345.1 - 0.009 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 KEY71346.1 - 1.4e-07 31.7 0.0 3.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY71346.1 - 4.5e-07 29.5 0.0 0.0039 17.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEY71346.1 - 0.0003 20.1 0.0 0.016 14.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KEY71346.1 - 0.0017 18.6 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 KEY71346.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.6 KEY71346.1 - 0.018 15.0 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_24 PF13479.6 KEY71346.1 - 0.048 13.4 0.0 3.5 7.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 KEY71347.1 - 5.8e-93 311.6 0.0 5.6e-88 295.3 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KEY71347.1 - 4.2e-05 24.0 0.0 0.018 15.4 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KEY71347.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY71347.1 - 0.0048 17.2 0.0 0.024 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEY71347.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KEY71347.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KEY71347.1 - 0.02 14.8 0.3 0.51 10.1 0.1 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein AAA PF00004.29 KEY71347.1 - 0.027 14.9 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEY71347.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Cupredoxin_1 PF13473.6 KEY71347.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain RNA_helicase PF00910.22 KEY71347.1 - 0.09 13.2 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KEY71347.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NOA36 PF06524.12 KEY71347.1 - 4.3 6.6 10.7 7.2 5.8 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KEY71347.1 - 6.3 7.2 14.5 19 5.7 14.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1295 PF06966.12 KEY71348.1 - 5.7e-20 71.8 0.0 7.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KEY71348.1 - 8.1e-07 28.1 2.4 2.3e-06 26.7 2.4 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KEY71348.1 - 0.00015 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.11 KEY71348.1 - 0.0095 15.5 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 1 NnrU protein SH3_9 PF14604.6 KEY71349.1 - 2.9e-11 43.0 0.0 4.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY71349.1 - 3.1e-09 36.3 0.0 4.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEY71349.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KEY71349.1 - 2.5e-05 23.6 0.6 4.4e-05 22.8 0.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 KEY71349.1 - 0.00061 20.0 0.2 0.0041 17.3 0.0 2.3 2 1 0 2 2 2 1 Glycophorin A TMEM51 PF15345.6 KEY71349.1 - 0.0028 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 KEY71349.1 - 0.054 14.4 0.0 0.09 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KEY71349.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 1 1 2 2 2 0 Orf78 (ac78) Amnionless PF14828.6 KEY71349.1 - 0.065 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Trp_oprn_chp PF09534.10 KEY71349.1 - 0.15 11.9 2.0 0.27 11.0 2.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2615 PF11027.8 KEY71349.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Syndecan PF01034.20 KEY71349.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain OAD_gamma PF04277.13 KEY71349.1 - 0.22 12.1 2.7 0.23 12.1 0.0 2.3 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CVNH PF08881.10 KEY71350.1 - 2.1e-12 47.6 0.0 3.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Toxin_22 PF08092.11 KEY71350.1 - 0.26 11.4 0.3 0.26 11.4 0.3 1.7 2 0 0 2 2 2 0 Magi peptide toxin family IBR PF01485.21 KEY71351.1 - 8.2e-06 26.0 4.7 8.2e-06 26.0 4.7 4.2 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain adh_short PF00106.25 KEY71352.1 - 2.3e-82 275.2 11.3 2.6e-43 147.7 0.8 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71352.1 - 5.4e-65 219.2 4.5 6e-34 117.6 0.2 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KEY71352.1 - 2e-33 114.6 0.0 4.1e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KEY71352.1 - 1.1e-26 93.9 3.5 1.8e-13 50.8 0.4 3.0 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.19 KEY71352.1 - 0.00072 18.9 0.5 0.0038 16.6 0.2 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KEY71352.1 - 0.0025 17.9 0.0 2.5 8.3 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase PglL_A PF15864.5 KEY71352.1 - 1.2 8.9 6.6 5.5 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase KAP_NTPase PF07693.14 KEY71353.1 - 3.7e-05 23.1 0.0 5.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain SRP54 PF00448.22 KEY71353.1 - 6.9e-05 22.6 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KEY71353.1 - 0.00024 21.7 0.0 0.00067 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KEY71353.1 - 0.00041 20.1 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KEY71353.1 - 0.0015 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KEY71353.1 - 0.0061 17.0 0.0 0.009 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KEY71353.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dNK PF01712.19 KEY71353.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 KEY71353.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 KEY71353.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 KEY71353.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family cobW PF02492.19 KEY71353.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 KEY71353.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 KEY71353.1 - 0.038 13.9 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KEY71353.1 - 0.049 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY71353.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY71353.1 - 0.099 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.14 KEY71353.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 KEY71353.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 KEY71353.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_33 PF13671.6 KEY71353.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY71353.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KEY71353.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 NTPase ECM11 PF15463.6 KEY71354.1 - 2.2e-43 148.0 10.5 2.2e-43 148.0 10.5 2.1 2 0 0 2 2 2 1 Extracellular mutant protein 11 DUF641 PF04859.12 KEY71354.1 - 0.03 14.6 2.7 0.086 13.2 2.7 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MAT1 PF06391.13 KEY71354.1 - 0.043 13.6 6.2 0.13 12.1 6.2 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CSN5_C PF18323.1 KEY71354.1 - 0.98 10.4 7.1 0.18 12.8 1.2 2.9 2 2 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain zf-U11-48K PF05253.12 KEY71355.1 - 0.032 14.1 0.4 0.11 12.5 0.4 1.9 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger F-box-like PF12937.7 KEY71355.1 - 0.068 13.1 2.2 0.075 12.9 0.0 2.4 2 1 0 2 2 2 0 F-box-like Pyrid_ox_like PF16242.5 KEY71356.1 - 3.4e-23 81.9 0.0 5.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KEY71356.1 - 2.8e-08 33.8 0.0 5.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KEY71356.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain TP_methylase PF00590.20 KEY71357.1 - 1.3e-22 80.8 0.0 2.2e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 KEY71358.1 - 3.2e-06 27.3 0.7 5.9e-06 26.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY71358.1 - 3.2e-05 24.2 0.7 5.6e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KEY71358.1 - 0.00054 20.0 1.3 0.0019 18.2 1.3 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KEY71358.1 - 0.024 14.8 0.2 0.045 13.9 0.2 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 KEY71358.1 - 0.028 14.7 0.1 0.063 13.6 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF4586 PF15239.6 KEY71358.1 - 0.043 14.0 0.6 0.043 14.0 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) zf-C2H2 PF00096.26 KEY71358.1 - 0.043 14.3 0.4 0.084 13.4 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-U1 PF06220.12 KEY71358.1 - 0.076 12.8 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF2165 PF09933.9 KEY71358.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) OrsD PF12013.8 KEY71358.1 - 0.37 11.2 3.6 0.2 12.1 0.7 1.9 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D AKAP95 PF04988.12 KEY71358.1 - 0.95 9.7 13.3 0.6 10.3 0.5 2.4 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) UQ_con PF00179.26 KEY71359.1 - 2.5e-35 121.2 0.0 2.7e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY71359.1 - 0.045 13.5 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.6 KEY71360.1 - 1.1e-05 25.8 0.0 3.5e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEY71360.1 - 0.00082 19.7 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.21 KEY71361.1 - 1.8e-48 165.0 3.8 2.4e-48 164.5 3.8 1.2 1 0 0 1 1 1 1 Cation efflux family Connexin PF00029.19 KEY71361.1 - 4.6 6.9 7.3 0.48 10.1 1.1 2.3 3 0 0 3 3 3 0 Connexin Mito_carr PF00153.27 KEY71362.1 - 1.4e-54 182.0 4.0 2.2e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 KEY71363.1 - 4.2e-06 26.6 0.0 0.84 9.3 0.0 4.1 4 0 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 KEY71364.1 - 2.8e-40 138.4 0.1 3.7e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 KEY71365.1 - 4.6e-19 69.1 0.0 3.8e-18 66.1 0.0 2.6 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KEY71365.1 - 0.059 13.3 0.5 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex SUR7 PF06687.12 KEY71366.1 - 1.3e-25 90.3 0.1 1.5e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KEY71366.1 - 0.019 14.9 0.6 0.019 14.9 0.6 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3678 PF12435.8 KEY71366.1 - 0.067 12.6 0.3 0.067 12.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF1772 PF08592.11 KEY71366.1 - 1.2 9.5 6.3 5.5 7.3 6.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DNA_pol_phi PF04931.13 KEY71366.1 - 1.4 6.9 9.4 1.9 6.5 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pex24p PF06398.11 KEY71366.1 - 7.9 5.3 5.5 23 3.8 0.0 2.8 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Ras PF00071.22 KEY71368.1 - 5e-40 136.8 0.0 1e-37 129.3 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEY71368.1 - 2.2e-31 108.5 0.0 3.1e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY71368.1 - 2.5e-10 40.1 0.0 4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEY71368.1 - 5.1e-05 23.3 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY71368.1 - 0.02 15.3 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RTP1_C2 PF10304.9 KEY71368.1 - 0.022 14.5 0.6 0.039 13.7 0.6 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 SRPRB PF09439.10 KEY71368.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KEY71368.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY71368.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DLIC PF05783.11 KEY71368.1 - 0.26 10.1 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Sec63 PF02889.16 KEY71369.1 - 1.7e-138 460.0 0.0 3.1e-81 272.3 0.2 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KEY71369.1 - 1e-49 168.7 0.2 1.3e-25 90.2 0.3 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KEY71369.1 - 2.6e-22 79.7 0.0 8.1e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY71369.1 - 1.1e-15 58.0 0.2 2e-06 28.1 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEY71369.1 - 6.6e-08 32.9 0.5 0.015 15.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KEY71369.1 - 1.6e-05 25.3 0.7 0.0043 17.4 0.5 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY71369.1 - 0.00053 20.4 0.1 3.7 8.0 0.0 4.4 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KEY71369.1 - 0.0014 18.8 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 KEY71369.1 - 0.038 13.1 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Synaptobrevin PF00957.21 KEY71370.1 - 1.9e-14 53.2 0.6 2.8e-14 52.7 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEY71370.1 - 5.2e-13 48.9 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain NB-ARC PF00931.22 KEY71372.1 - 5.5e-13 48.7 0.0 8.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KEY71372.1 - 1.4e-06 28.5 6.9 4.6e-05 23.6 1.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEY71372.1 - 0.00039 19.7 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_22 PF13401.6 KEY71372.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY71372.1 - 0.0024 18.3 0.1 0.015 15.7 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.6 KEY71372.1 - 0.0073 16.1 1.6 0.13 12.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY71372.1 - 0.0086 16.3 0.6 6.6 7.0 0.1 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_lid_8 PF17868.1 KEY71372.1 - 0.017 15.0 0.7 2.4 8.1 0.1 3.2 2 1 1 3 3 3 0 AAA lid domain NACHT PF05729.12 KEY71372.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TPR_7 PF13176.6 KEY71372.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY71372.1 - 0.38 11.3 2.1 5.2 7.7 0.1 3.8 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEY71372.1 - 1.6 9.1 3.7 9.6 6.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY71373.1 - 2e-30 103.7 20.7 0.00036 20.3 0.1 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KEY71373.1 - 6.3e-25 87.3 33.6 2.5e-07 30.9 2.0 4.1 2 1 3 5 5 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY71373.1 - 2.3e-15 56.5 6.9 0.035 14.3 0.0 6.3 1 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEY71373.1 - 8.2e-15 53.7 14.6 0.093 12.8 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KEY71373.1 - 8.8e-15 53.6 9.1 0.86 10.0 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEY71373.1 - 8.2e-12 45.5 17.6 0.084 13.4 0.1 6.4 1 1 4 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY71373.1 - 1.2e-11 44.4 16.7 2.8 9.0 0.1 7.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_20 PF14561.6 KEY71373.1 - 1.5e-10 41.3 28.3 0.17 12.2 0.5 7.0 1 1 6 7 7 7 6 Tetratricopeptide repeat Paf67 PF10255.9 KEY71373.1 - 1.7e-10 40.5 0.6 0.033 13.2 0.1 4.2 1 1 3 5 5 5 5 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.6 KEY71373.1 - 8.7e-08 32.3 6.8 2.8 8.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat ATP13 PF12921.7 KEY71373.1 - 5.3e-07 29.5 3.3 16 5.4 0.0 6.2 3 2 4 7 7 7 0 Mitochondrial ATPase expression PPR PF01535.20 KEY71373.1 - 1.7e-06 27.9 7.5 16 6.0 0.1 6.5 7 0 0 7 7 7 0 PPR repeat AAA_lid_8 PF17868.1 KEY71373.1 - 1.1e-05 25.2 11.2 0.17 11.8 0.2 5.4 2 1 3 5 5 5 3 AAA lid domain E2F_TDP PF02319.20 KEY71373.1 - 3.4e-05 23.8 14.6 3.4 7.8 0.2 6.0 3 2 2 6 6 6 3 E2F/DP family winged-helix DNA-binding domain WHAMM-JMY_N PF15920.5 KEY71373.1 - 4.9e-05 23.1 2.6 54 3.8 0.0 6.2 7 0 0 7 7 7 0 N-terminal of Junction-mediating and WASP homolog-associated TPR_2 PF07719.17 KEY71373.1 - 5.4e-05 23.0 9.0 48 4.4 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_115 PF15979.5 KEY71373.1 - 9.3e-05 22.0 14.7 0.89 8.9 0.3 5.2 1 1 6 7 7 7 3 Glycosyl hydrolase family 115 DUF4248 PF14053.6 KEY71373.1 - 9.4e-05 22.4 2.6 81 3.3 0.0 6.4 7 0 0 7 7 7 0 Domain of unknown function (DUF4248) PPR_1 PF12854.7 KEY71373.1 - 0.00024 20.7 5.3 2.1 8.1 0.1 6.1 7 0 0 7 7 7 1 PPR repeat Bombinin PF05298.11 KEY71373.1 - 0.0015 18.2 27.6 0.2 11.4 2.1 5.6 1 1 4 5 5 5 3 Bombinin Plectin PF00681.20 KEY71373.1 - 0.0033 17.3 1.8 49 3.9 0.0 5.3 5 1 0 5 5 5 0 Plectin repeat TPR_4 PF07721.14 KEY71373.1 - 0.095 13.4 5.0 5.1 8.0 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat GFD1 PF17331.2 KEY71373.1 - 0.5 10.6 2.9 1.5e+02 2.8 0.0 4.1 3 0 0 3 3 3 0 GFD1 mRNA transport factor Corazonin PF17308.2 KEY71373.1 - 0.52 10.7 2.4 37 4.7 0.1 3.3 2 2 1 3 3 3 0 Pro-corazonin NurA PF09376.10 KEY71373.1 - 5.6 6.6 11.6 5.9 6.5 1.3 3.2 1 1 1 2 2 2 0 NurA domain Glyco_hydro_43 PF04616.14 KEY71374.1 - 0.00077 18.9 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5384 PF17358.2 KEY71376.1 - 0.028 14.5 0.6 0.052 13.6 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) RPA_interact_M PF14767.6 KEY71376.1 - 0.086 13.4 0.4 0.21 12.2 0.3 1.7 1 1 0 1 1 1 0 Replication protein A interacting middle MYO10_CC PF16735.5 KEY71377.1 - 0.067 13.3 6.7 0.32 11.1 6.7 2.2 1 1 0 1 1 1 0 Unconventional myosin-X coiled coil domain DUF5327 PF17261.2 KEY71377.1 - 0.14 13.0 0.3 0.3 11.8 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) G-gamma PF00631.22 KEY71377.1 - 0.25 11.4 1.3 26 4.9 0.0 2.5 2 0 0 2 2 2 0 GGL domain Cwf_Cwc_15 PF04889.12 KEY71377.1 - 0.44 10.2 4.3 0.67 9.6 4.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.12 KEY71378.1 - 1.8e-19 70.3 8.0 2.1e-19 70.0 8.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KEY71378.1 - 0.0023 17.9 5.9 0.004 17.1 5.9 1.5 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 CorA PF01544.18 KEY71379.1 - 9.6e-06 25.1 0.2 1.9e-05 24.1 0.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DEAD PF00270.29 KEY71380.1 - 5.3e-43 146.8 0.0 1.7e-39 135.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71380.1 - 4.6e-23 81.7 0.0 3.9e-22 78.7 0.0 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY71380.1 - 2.6e-05 24.3 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit p450 PF00067.22 KEY71382.1 - 1.2e-49 169.3 0.0 1.6e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEY71385.1 - 4.4e-19 68.6 14.1 4.4e-19 68.6 14.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71385.1 - 0.00054 18.9 2.8 0.0012 17.9 2.8 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter ApoL PF05461.11 KEY71385.1 - 0.18 11.1 1.6 0.45 9.8 1.1 1.8 2 0 0 2 2 2 0 Apolipoprotein L PCI PF01399.27 KEY71386.1 - 0.003 18.0 0.1 4 8.0 0.0 2.5 2 0 0 2 2 2 2 PCI domain SUN PF03856.13 KEY71387.1 - 3.6e-74 249.3 10.7 4.7e-74 248.9 10.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sporozoite_P67 PF05642.11 KEY71387.1 - 1.8 6.5 24.0 0.0066 14.6 13.8 1.7 1 1 1 2 2 2 0 Sporozoite P67 surface antigen PCM1_C PF15717.5 KEY71387.1 - 7.2 5.2 14.4 9.5 4.8 14.4 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus GTP_EFTU PF00009.27 KEY71388.1 - 3.8e-47 160.4 0.0 7e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KEY71388.1 - 3.2e-19 68.8 0.0 5.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEY71388.1 - 1.9e-10 40.6 0.0 3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEY71388.1 - 0.0038 17.6 0.1 0.016 15.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 DUF615 PF04751.14 KEY71388.1 - 0.0081 16.2 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF615) COPI_assoc PF08507.10 KEY71389.1 - 1.1e-27 96.6 6.8 2.1e-27 95.7 6.8 1.5 1 1 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 KEY71389.1 - 0.0074 15.6 0.5 0.0074 15.6 0.5 2.0 3 0 0 3 3 3 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Mannosyl_trans4 PF15971.5 KEY71389.1 - 0.036 13.9 0.2 0.036 13.9 0.2 1.8 1 1 1 2 2 2 0 DolP-mannose mannosyltransferase Senescence PF06911.12 KEY71390.1 - 0.0083 16.5 1.4 0.012 15.9 1.4 1.3 1 1 0 1 1 1 1 Senescence-associated protein Chlorosome_CsmC PF11098.8 KEY71390.1 - 0.036 14.1 3.4 0.047 13.7 3.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C VPS13_C PF16909.5 KEY71390.1 - 2.1 8.1 3.7 0.54 10.0 1.1 1.4 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal DEAD PF00270.29 KEY71391.1 - 3.2e-44 150.8 0.1 7.8e-44 149.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71391.1 - 3.5e-19 69.2 0.0 1.2e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEY71391.1 - 4.4e-17 62.1 0.0 9.2e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEY71391.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PPR_2 PF13041.6 KEY71392.1 - 6.2e-41 138.4 10.7 1e-08 35.2 0.0 14.8 11 5 6 17 17 17 7 PPR repeat family PPR_3 PF13812.6 KEY71392.1 - 9.8e-31 105.6 0.0 0.0025 17.9 0.0 10.7 9 2 2 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 KEY71392.1 - 2.8e-23 80.5 18.7 0.0015 18.7 0.0 13.3 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.7 KEY71392.1 - 5.3e-21 74.0 0.1 2.1e-07 30.5 0.0 10.4 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 KEY71392.1 - 1.8e-17 63.4 5.9 3.9e-08 32.9 0.1 6.5 5 2 0 6 6 6 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KEY71392.1 - 5.9e-05 23.5 0.0 0.0033 17.8 0.0 3.5 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 KEY71392.1 - 0.049 13.7 0.4 23 5.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP13 PF12921.7 KEY71392.1 - 0.06 13.2 1.3 0.62 9.9 0.2 3.2 3 1 1 4 4 4 0 Mitochondrial ATPase expression GHMP_kinases_N PF00288.26 KEY71393.1 - 1.8e-15 56.9 3.4 5.8e-15 55.3 3.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEY71393.1 - 2.6e-09 37.3 0.0 5.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Bac_rhamnosid_C PF17390.2 KEY71394.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain MGAT2 PF05060.14 KEY71394.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Aldedh PF00171.22 KEY71395.1 - 1e-130 436.4 0.0 1.1e-130 436.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEY71395.1 - 6.3e-05 22.2 0.0 0.00015 21.0 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KEY71395.1 - 0.027 13.9 0.0 3.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.22 KEY71396.1 - 7.3e-06 25.7 0.0 0.00074 19.3 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.12 KEY71399.1 - 1e-47 162.8 0.2 1.6e-47 162.1 0.2 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Phage_H_T_join PF05521.11 KEY71399.1 - 0.0052 17.3 0.5 0.011 16.2 0.5 1.5 1 0 0 1 1 1 1 Phage head-tail joining protein Pterin_bind PF00809.22 KEY71400.1 - 2.1e-77 260.1 0.0 2.8e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KEY71400.1 - 7.4e-37 126.3 0.0 1.8e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 KEY71401.1 - 2.3e-56 191.6 1.1 3.4e-56 191.0 1.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEY71401.1 - 1.1e-11 44.3 2.7 1.7e-11 43.8 2.7 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY71401.1 - 6.6e-06 25.4 3.6 1.1e-05 24.6 3.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEY71401.1 - 0.012 14.8 1.4 0.02 14.0 1.4 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KEY71401.1 - 0.044 13.0 0.6 0.067 12.4 0.6 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.14 KEY71401.1 - 0.12 11.5 0.1 0.28 10.4 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ArfGap PF01412.18 KEY71402.1 - 5.1e-32 110.4 0.1 9.6e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 KEY71403.1 - 7.7e-43 145.8 0.1 9.3e-43 145.6 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KEY71403.1 - 0.003 17.3 0.0 0.0069 16.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 B12D PF06522.11 KEY71403.1 - 0.034 14.0 0.7 6.1 6.7 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-H2C2_2 PF13465.6 KEY71405.1 - 2.1e-07 31.0 26.0 1.8e-05 25.0 3.5 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KEY71405.1 - 9.4e-06 25.8 14.0 0.0004 20.7 4.5 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KEY71405.1 - 0.014 15.6 3.0 0.047 14.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KEY71405.1 - 0.038 14.3 5.4 0.094 13.0 5.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KEY71405.1 - 0.045 14.6 3.1 0.045 14.6 3.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2225 PF09986.9 KEY71405.1 - 0.39 10.4 1.0 0.94 9.2 1.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) FOXP-CC PF16159.5 KEY71405.1 - 0.45 11.2 8.5 0.13 12.9 3.5 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KEY71405.1 - 1.4 8.8 12.4 2.6 7.9 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad51 PF08423.11 KEY71406.1 - 7.2e-11 41.8 0.0 4.6e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KEY71406.1 - 0.00013 21.6 0.9 0.00072 19.1 0.1 2.2 2 1 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 KEY71406.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.17 KEY71406.1 - 0.008 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KEY71406.1 - 0.064 12.8 0.4 0.24 11.0 0.4 2.0 1 1 0 1 1 1 0 AAA domain Bromodomain PF00439.25 KEY71407.1 - 6e-16 58.3 0.0 1.7e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Bromodomain BTB PF00651.31 KEY71407.1 - 2.6e-05 24.4 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ACBP PF00887.19 KEY71409.1 - 8.2e-24 83.6 0.2 9.4e-24 83.4 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 KEY71410.1 - 3.7e-32 111.7 1.4 4.6e-32 111.4 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY71410.1 - 4.2e-09 36.8 2.0 1.7e-06 28.5 1.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY71410.1 - 0.14 12.2 4.7 8.5 6.4 0.0 3.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KEY71410.1 - 0.14 12.5 2.3 8.5 6.7 0.1 2.9 3 0 0 3 3 3 0 TrkA-N domain K_oxygenase PF13434.6 KEY71410.1 - 0.15 11.2 0.3 0.4 9.8 0.1 1.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KEY71410.1 - 0.33 9.9 3.5 2 7.4 0.0 3.1 3 1 1 4 4 4 0 Lycopene cyclase protein End3 PF12761.7 KEY71411.1 - 6.1e-78 261.6 3.6 8.1e-78 261.2 3.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KEY71411.1 - 3e-48 162.1 0.0 1.6e-46 156.6 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KEY71411.1 - 6.8e-07 28.4 0.2 6.8e-07 28.4 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KEY71411.1 - 1.7e-05 25.2 0.1 0.0001 22.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEY71411.1 - 0.00021 20.9 0.1 0.0028 17.5 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KEY71411.1 - 0.00074 19.3 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KEY71411.1 - 0.057 12.9 0.2 0.057 12.9 0.2 2.5 2 0 0 2 2 2 0 EF hand COG2 PF06148.11 KEY71411.1 - 2 8.5 4.5 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CSN5_C PF18323.1 KEY71411.1 - 4.7 8.2 5.5 1.2 10.1 1.4 2.2 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DHR10 PF18595.1 KEY71411.1 - 7.3 6.7 13.3 4.7 7.3 0.2 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain NUDIX PF00293.28 KEY71412.1 - 8.6e-26 90.5 0.0 1.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 KEY71413.1 - 7.8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY71413.1 - 8.1e-07 29.4 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY71413.1 - 4e-06 26.9 0.0 8.9e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY71413.1 - 0.0002 21.3 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY71413.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY71413.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.11 KEY71414.1 - 1.6e-20 73.7 0.1 3.5e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KEY71414.1 - 7.6e-08 32.2 0.7 3.4e-07 30.1 0.1 2.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF5011 PF16403.5 KEY71414.1 - 0.0046 17.1 1.7 0.11 12.6 0.7 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5011) RMI2 PF16100.5 KEY71414.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Lon_C PF05362.13 KEY71415.1 - 4.5e-67 225.6 0.6 8.1e-67 224.7 0.6 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KEY71415.1 - 1.7e-24 86.8 0.0 8.2e-24 84.5 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KEY71415.1 - 2.2e-24 86.5 0.0 5.2e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KEY71415.1 - 1.4e-08 34.9 0.0 5e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KEY71415.1 - 5.7e-07 29.4 0.2 2.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KEY71415.1 - 6.3e-06 26.7 0.4 2.8e-05 24.6 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KEY71415.1 - 7.3e-06 25.8 0.0 2.3e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KEY71415.1 - 3.5e-05 24.1 0.1 0.0089 16.3 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KEY71415.1 - 4.9e-05 23.2 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEY71415.1 - 0.00029 20.6 0.0 0.0008 19.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEY71415.1 - 0.00037 20.7 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KEY71415.1 - 0.0043 17.2 0.1 0.0088 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEY71415.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEY71415.1 - 0.024 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEY71415.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KEY71415.1 - 0.028 14.2 0.3 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KEY71415.1 - 0.036 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 KEY71415.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY71415.1 - 0.04 14.5 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEY71415.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KEY71415.1 - 0.066 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 KEY71415.1 - 0.071 12.0 0.0 1.1 8.1 0.1 2.2 2 0 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.22 KEY71415.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 KEY71415.1 - 0.083 13.4 3.4 0.2 12.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEY71415.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEY71415.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase Rad17 PF03215.15 KEY71415.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KEY71415.1 - 0.11 12.3 0.1 0.37 10.7 0.1 1.9 1 1 0 1 1 1 0 NTPase TsaE PF02367.17 KEY71415.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HflK_N PF12221.8 KEY71415.1 - 0.29 11.1 3.5 0.45 10.6 2.2 2.0 1 1 1 2 2 2 0 Bacterial membrane protein N terminal V_ATPase_I PF01496.19 KEY71415.1 - 0.3 9.0 0.2 0.43 8.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KEY71415.1 - 0.95 8.3 4.7 1.7 7.5 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Zn_clus PF00172.18 KEY71416.1 - 9.1e-07 28.9 11.5 1.4e-06 28.3 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 KEY71417.1 - 0.12 12.5 0.8 0.58 10.4 0.2 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat DUF3391 PF11871.8 KEY71417.1 - 0.63 10.6 8.3 0.4 11.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) eIF3g PF12353.8 KEY71418.1 - 3.3e-43 147.1 1.6 5.7e-43 146.3 1.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KEY71418.1 - 1.5e-15 56.7 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KEY71418.1 - 0.024 14.9 0.2 0.047 14.0 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 KEY71418.1 - 0.19 11.6 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif CYSTM PF12734.7 KEY71419.1 - 6.4e-11 42.4 8.8 6.4e-11 42.4 8.8 4.9 3 2 0 3 3 3 1 Cysteine-rich TM module stress tolerance RSN1_7TM PF02714.15 KEY71420.1 - 7.2e-75 251.8 23.6 2.2e-74 250.3 23.6 1.9 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY71420.1 - 1.1e-43 148.6 0.5 1.1e-43 148.6 0.5 3.6 4 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEY71420.1 - 1.2e-30 107.0 1.6 2.6e-17 63.6 0.1 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEY71420.1 - 1.3e-16 60.5 0.0 6.1e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter CENP-H PF05837.12 KEY71420.1 - 0.51 10.8 6.8 1.3 9.4 6.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Abhydrolase_1 PF00561.20 KEY71421.1 - 3.7e-22 79.2 0.0 7.3e-18 65.1 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY71421.1 - 3.2e-15 56.0 0.0 2e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY71421.1 - 1.6e-13 51.8 2.3 2.4e-13 51.2 0.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KEY71421.1 - 8.4e-06 25.3 0.0 2e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KEY71421.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 KEY71421.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KEY71421.1 - 0.01 15.6 0.0 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEY71421.1 - 0.049 13.5 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KEY71421.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KEY71421.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KEY71421.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 KEY71421.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KEY71421.1 - 0.22 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Spo7 PF03907.13 KEY71423.1 - 1.2e-93 312.7 0.4 1.8e-93 312.1 0.4 1.3 1 0 0 1 1 1 1 Spo7-like protein Fringe PF02434.16 KEY71424.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like SLATT_fungal PF18142.1 KEY71425.1 - 8.2e-27 93.6 0.0 1.1e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain TRM PF02005.16 KEY71426.1 - 2.4e-107 359.4 0.0 6.2e-93 312.0 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KEY71426.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_3 PF01596.17 KEY71426.1 - 0.058 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DAGK_cat PF00781.24 KEY71427.1 - 7.7e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lectin_leg-like PF03388.13 KEY71427.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF4757 PF15949.5 KEY71427.1 - 0.03 14.8 0.2 0.056 13.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) ABC_tran PF00005.27 KEY71428.1 - 3.4e-44 150.7 0.2 1.5e-22 80.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY71428.1 - 4.2e-09 36.2 0.0 0.011 15.2 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEY71428.1 - 9.3e-08 32.2 10.5 0.2 11.4 0.4 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY71428.1 - 1.7e-06 27.7 1.7 0.039 13.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 KEY71428.1 - 2.6e-06 27.4 2.3 2.6e-06 27.4 2.3 2.2 2 1 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 KEY71428.1 - 1.6e-05 24.9 0.7 0.036 14.1 0.1 3.2 4 0 0 4 4 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY71428.1 - 0.00011 22.5 0.9 0.44 10.8 0.2 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY71428.1 - 0.00021 21.2 3.1 0.29 11.0 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_7 PF12775.7 KEY71428.1 - 0.002 17.7 0.1 0.92 9.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KEY71428.1 - 0.0022 18.6 0.1 1.2 9.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEY71428.1 - 0.0043 17.0 1.1 1.7 8.7 0.1 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEY71428.1 - 0.0049 16.6 0.4 2.1 8.0 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY71428.1 - 0.0052 16.5 3.1 0.37 10.5 0.1 3.5 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 KEY71428.1 - 0.0065 16.7 0.2 2.4 8.4 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KEY71428.1 - 0.0084 16.2 9.7 0.031 14.4 0.5 3.2 4 0 0 4 4 4 2 Helicase HerA, central domain Zeta_toxin PF06414.12 KEY71428.1 - 0.014 14.7 0.1 0.62 9.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KEY71428.1 - 0.014 15.5 2.4 0.99 9.6 0.2 2.9 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 KEY71428.1 - 0.02 13.9 1.8 0.22 10.5 0.2 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KEY71428.1 - 0.021 15.2 0.2 8.3 6.9 0.1 2.5 2 0 0 2 2 2 0 RNA helicase Vfa1 PF08432.10 KEY71428.1 - 0.025 14.9 0.2 0.067 13.5 0.2 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_16 PF13191.6 KEY71428.1 - 0.025 15.0 8.2 0.25 11.7 0.1 3.3 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEY71428.1 - 0.029 14.3 0.3 7.4 6.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 KEY71428.1 - 0.033 13.9 7.7 0.28 10.8 0.1 3.5 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 KEY71428.1 - 0.033 14.7 17.6 0.28 11.7 0.4 4.1 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KEY71428.1 - 0.042 14.1 5.9 0.074 13.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 KEY71428.1 - 0.11 12.1 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 KEY71428.1 - 0.18 11.7 0.6 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DSPc PF00782.20 KEY71429.1 - 6.1e-24 84.3 0.0 3.4e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEY71429.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.11 KEY71430.1 - 2.4e-45 155.1 2.0 3.2e-45 154.6 2.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEY71430.1 - 5.8e-09 36.2 23.8 1e-06 29.0 4.1 3.6 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KEY71430.1 - 6.4e-06 25.6 1.4 0.01 15.0 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter SPW PF03779.14 KEY71430.1 - 0.086 12.4 0.1 0.086 12.4 0.1 3.2 3 0 0 3 3 3 0 SPW repeat CRT-like PF08627.10 KEY71430.1 - 0.13 11.2 6.0 0.38 9.6 0.2 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 KEY71430.1 - 0.15 12.1 5.1 0.059 13.4 1.9 2.0 2 0 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 KEY71430.1 - 0.18 11.2 8.9 0.15 11.4 1.1 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family KH_1 PF00013.29 KEY71431.1 - 2e-40 136.4 10.8 1e-15 57.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEY71431.1 - 2.3e-10 40.1 9.5 0.0024 17.6 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEY71431.1 - 2.9e-08 33.5 4.6 0.028 14.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KEY71431.1 - 1.8e-05 24.8 5.0 0.24 11.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KEY71431.1 - 0.032 14.2 0.0 16 5.6 0.0 2.9 3 0 0 3 3 3 0 KH-like RNA-binding domain RabGAP-TBC PF00566.18 KEY71433.1 - 5.1e-27 94.9 0.1 9.5e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KEY71434.1 - 1.7e-50 171.9 0.0 3.9e-50 170.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71434.1 - 1.4e-18 67.1 0.0 3.3e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71434.1 - 0.0016 17.8 0.3 0.69 9.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEY71434.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KEY71435.1 - 2 8.8 5.7 3.8 7.9 5.7 1.4 1 0 0 1 1 1 0 C1 domain Siva PF05458.12 KEY71435.1 - 2.1 8.0 6.4 3.3 7.4 5.4 1.8 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Glucosamine_iso PF01182.20 KEY71436.1 - 2.6e-67 227.0 0.0 2.9e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF3176 PF11374.8 KEY71437.1 - 8.6e-32 109.5 1.1 1.5e-31 108.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) GMC_oxred_N PF00732.19 KEY71438.1 - 1.2e-38 133.2 0.0 1.6e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY71438.1 - 1.5e-05 25.6 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase HTH_6 PF01418.17 KEY71439.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Lyase_1 PF00206.20 KEY71441.1 - 2.6e-35 122.3 0.0 4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KEY71441.1 - 7.2e-11 42.7 0.7 2.1e-10 41.2 0.7 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DDE_Tnp_1_7 PF13843.6 KEY71443.1 - 1.4e-32 113.4 0.0 1.2e-15 57.7 0.0 2.2 1 1 1 2 2 2 2 Transposase IS4 Suf PF05843.14 KEY71443.1 - 0.085 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3425 PF11905.8 KEY71444.1 - 6.9e-19 68.0 0.1 2.4e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) HET PF06985.11 KEY71445.1 - 3e-26 92.5 0.1 7.9e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.30 KEY71445.1 - 2.2e-15 56.3 0.1 1.9e-05 24.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KEY71445.1 - 2.1e-14 53.4 1.9 1.9e-06 28.0 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY71445.1 - 6.2e-13 49.2 0.0 4.1e-07 30.5 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY71445.1 - 5.9e-11 42.7 0.2 5.3e-05 23.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY71445.1 - 4.8e-09 35.7 0.8 0.0061 17.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat NPV_P10 PF05531.12 KEY71446.1 - 0.031 14.7 0.5 0.042 14.3 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Integrin_beta PF00362.18 KEY71446.1 - 0.071 12.8 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Integrin beta chain VWA domain MULE PF10551.9 KEY71447.1 - 2.1e-26 92.2 0.6 5.5e-26 90.8 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 KEY71447.1 - 7.6e-06 26.5 0.3 2.3e-05 25.0 0.3 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain zf-C2H2_10 PF16588.5 KEY71447.1 - 0.016 14.9 2.2 0.038 13.7 2.2 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger Transposase_mut PF00872.18 KEY71447.1 - 0.022 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Transposase, Mutator family SPATA3 PF15662.5 KEY71447.1 - 6.3 7.4 11.9 3.6 8.2 0.7 3.6 3 0 0 3 3 3 0 Spermatogenesis-associated protein 3 family CN_hydrolase PF00795.22 KEY71448.1 - 5.8e-07 29.1 0.0 6.9e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Actin PF00022.19 KEY71449.1 - 3.7e-16 58.7 0.0 7.4e-14 51.2 0.0 2.2 2 0 0 2 2 2 2 Actin Ysc84 PF04366.12 KEY71450.1 - 1.8e-30 105.3 0.0 3.8e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator F-box PF00646.33 KEY71451.1 - 0.17 11.8 1.2 0.5 10.3 0.1 2.3 3 0 0 3 3 3 0 F-box domain Fungal_trans PF04082.18 KEY71453.1 - 1.9e-17 63.1 1.5 4.6e-17 61.9 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KEY71453.1 - 1.4e-06 28.4 7.3 1.8e-05 24.9 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KEY71453.1 - 0.0008 19.7 4.4 0.0015 18.7 4.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KEY71453.1 - 0.2 12.0 3.1 8.7 6.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KEY71453.1 - 0.37 11.3 14.6 0.37 11.3 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY71453.1 - 0.42 11.6 23.2 0.063 14.2 5.8 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MRP-L47 PF06984.13 KEY71454.1 - 1.9e-25 88.8 0.2 3.2e-25 88.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KEY71454.1 - 0.29 10.6 1.7 0.55 9.7 1.7 1.4 1 0 0 1 1 1 0 Clc-like GDI PF00996.18 KEY71455.1 - 1.2e-187 623.8 0.0 1.3e-187 623.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KEY71455.1 - 0.032 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY71455.1 - 0.1 13.2 0.2 0.66 10.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NOG1_N PF17835.1 KEY71456.1 - 1.4e-49 168.1 0.2 1.4e-49 168.1 0.2 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KEY71456.1 - 7.4e-28 96.3 2.4 2.1e-27 94.9 2.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KEY71456.1 - 4.3e-26 90.5 0.6 9.6e-26 89.3 0.6 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KEY71456.1 - 1e-15 57.8 0.0 2.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY71456.1 - 9.9e-08 31.7 0.0 2.1e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEY71456.1 - 0.044 13.7 2.0 3.6 7.4 0.0 3.5 4 1 0 4 4 4 0 RsgA GTPase Roc PF08477.13 KEY71456.1 - 0.063 13.5 0.4 0.77 10.0 0.0 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KEY71456.1 - 0.077 13.4 6.0 0.2 12.0 0.0 3.6 3 1 1 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.23 KEY71456.1 - 0.097 12.7 3.9 4.1 7.4 0.0 3.2 3 1 1 4 4 4 0 Dynamin family NTP_transf_6 PF06042.11 KEY71456.1 - 0.1 12.4 0.1 0.4 10.5 0.1 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase Asp_protease PF09668.10 KEY71457.1 - 3.7e-59 197.9 0.1 5.5e-59 197.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KEY71457.1 - 2.4e-23 82.5 0.1 5.7e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KEY71457.1 - 2e-11 44.4 0.1 4.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KEY71457.1 - 9.5e-08 31.7 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEY71457.1 - 4.2e-07 29.7 0.2 9.8e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 KEY71457.1 - 4e-05 23.4 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KEY71457.1 - 9.4e-05 22.7 0.0 0.00028 21.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 KEY71457.1 - 0.014 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.6 KEY71457.1 - 0.04 13.8 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain EssA PF10661.9 KEY71457.1 - 0.17 11.7 2.4 0.29 11.0 2.4 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Methyltransf_8 PF05148.15 KEY71458.1 - 1e-59 202.0 0.0 1.6e-57 194.8 0.0 2.8 2 1 1 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KEY71458.1 - 7.5e-06 26.5 0.0 0.00018 22.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71458.1 - 0.00016 22.3 0.0 0.016 15.9 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEY71458.1 - 0.025 14.1 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KEY71458.1 - 0.038 14.0 0.6 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71458.1 - 0.038 13.8 0.0 0.52 10.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_1g PF09334.11 KEY71458.1 - 0.12 11.1 0.0 0.27 9.9 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (M) NARP1 PF12569.8 KEY71458.1 - 7.2 5.4 11.5 12 4.7 11.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Fungal_trans_2 PF11951.8 KEY71459.1 - 3.4e-19 68.9 0.0 2.1e-12 46.6 0.9 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71459.1 - 5.5e-08 32.8 11.6 1e-07 31.9 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY71459.1 - 0.039 13.0 4.3 0.26 10.3 4.3 2.1 1 1 0 1 1 1 0 Fungal specific transcription factor domain Proteasome PF00227.26 KEY71460.1 - 4.8e-56 189.3 0.1 6.1e-56 188.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEY71460.1 - 3.9e-10 39.2 0.0 9e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KEY71461.1 - 3.3e-62 210.9 0.0 6.4e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KEY71461.1 - 2.2e-61 208.0 1.1 3.7e-61 207.3 1.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal SNF2_N PF00176.23 KEY71462.1 - 2.6e-70 236.9 0.0 3.7e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY71462.1 - 1.5e-11 44.6 0.0 3.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KEY71462.1 - 3.2e-05 23.8 3.3 7.2e-05 22.7 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KEY71462.1 - 9.7e-05 22.2 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEY71462.1 - 0.0028 17.7 0.1 0.013 15.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KEY71462.1 - 0.011 15.5 1.0 0.011 15.5 1.0 1.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEY71462.1 - 0.013 15.5 0.5 0.036 14.1 0.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KEY71462.1 - 0.016 15.6 0.7 0.038 14.3 0.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KEY71462.1 - 0.019 14.9 4.4 0.06 13.2 4.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY71462.1 - 2.6 8.3 5.0 0.53 10.5 1.3 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KEY71462.1 - 4.4 7.2 7.9 0.21 11.5 0.2 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SRP68 PF16969.5 KEY71463.1 - 1.7e-193 644.6 0.0 2e-193 644.5 0.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 HSP70 PF00012.20 KEY71465.1 - 4e-267 887.3 14.7 4.7e-267 887.1 14.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEY71465.1 - 9.3e-14 51.0 4.3 9.2e-12 44.4 1.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KEY71465.1 - 0.0003 20.6 0.1 0.00092 19.0 0.1 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SMBP PF16785.5 KEY71465.1 - 0.066 13.4 6.6 0.21 11.8 6.6 1.9 1 0 0 1 1 1 0 Small metal-binding protein Big_3_4 PF13754.6 KEY71465.1 - 0.096 12.4 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function WD40 PF00400.32 KEY71466.1 - 2.3e-17 63.0 12.1 0.00013 22.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.6 KEY71467.1 - 1.2e-36 126.7 0.0 1.6e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KEY71467.1 - 2.3e-09 37.2 6.7 4.2e-09 36.3 6.7 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KEY71467.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 CUE domain DMA PF03474.14 KEY71467.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif DUF2415 PF10313.9 KEY71468.1 - 6.8e-12 45.1 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KEY71468.1 - 0.00048 20.4 0.0 1.6 9.0 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KEY71468.1 - 0.022 15.2 0.3 53 4.5 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 KEY71468.1 - 0.19 12.6 0.4 18 6.4 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat DAO PF01266.24 KEY71469.1 - 2.5e-59 201.7 7.6 2.9e-59 201.4 7.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEY71469.1 - 1.2e-05 24.9 1.6 0.00017 21.1 1.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY71469.1 - 1.8e-05 24.9 1.2 4.3e-05 23.7 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY71469.1 - 0.02 14.1 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY71469.1 - 0.031 14.8 0.1 0.064 13.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEY71469.1 - 0.041 13.2 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KEY71469.1 - 0.043 13.1 0.4 0.081 12.2 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KEY71469.1 - 0.051 12.6 0.4 0.072 12.2 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KEY71469.1 - 0.065 12.5 0.6 0.16 11.2 0.2 1.8 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.24 KEY71469.1 - 0.11 11.7 0.6 11 5.2 0.3 2.2 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase SlyX PF04102.12 KEY71470.1 - 0.00092 19.8 6.5 0.51 11.0 1.7 2.5 2 0 0 2 2 2 2 SlyX DUF2046 PF09755.9 KEY71470.1 - 0.0042 16.4 0.8 0.014 14.6 0.2 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Pox_A_type_inc PF04508.12 KEY71470.1 - 0.0061 16.4 0.6 0.0061 16.4 0.6 1.9 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DivIC PF04977.15 KEY71470.1 - 0.066 13.0 2.9 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1465 PF07323.12 KEY71470.1 - 0.12 12.2 2.4 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DASH_Spc34 PF08657.10 KEY71470.1 - 0.13 12.0 0.5 11 5.7 0.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 DMSP_lyase PF16867.5 KEY71470.1 - 0.14 11.8 2.3 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Mitofilin PF09731.9 KEY71470.1 - 0.21 10.4 4.8 0.35 9.7 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PriC PF07445.12 KEY71470.1 - 0.39 10.6 8.5 0.071 13.0 4.1 1.8 2 0 0 2 2 2 0 Primosomal replication protein priC PH PF00169.29 KEY71471.1 - 0.095 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 PH domain SBBP PF06739.11 KEY71472.1 - 0.038 14.0 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Beta-propeller repeat GSDH PF07995.11 KEY71472.1 - 0.15 11.3 0.5 0.35 10.1 0.5 1.7 1 1 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Syndecan PF01034.20 KEY71473.1 - 0.072 13.0 1.5 0.12 12.4 1.5 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 KEY71473.1 - 0.15 12.1 0.3 0.34 11.0 0.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Fungal_trans PF04082.18 KEY71474.1 - 8.1e-32 110.3 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71474.1 - 4.3e-09 36.4 9.3 6.8e-09 35.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RskA PF10099.9 KEY71475.1 - 0.012 16.0 0.9 0.016 15.5 0.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Utp13 PF08625.11 KEY71475.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain CW_7 PF08230.11 KEY71475.1 - 0.053 13.3 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 CW_7 repeat MFS_1 PF07690.16 KEY71476.1 - 2.7e-42 145.0 5.1 2.7e-42 145.0 5.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71476.1 - 7.1e-10 38.3 2.1 7.1e-10 38.3 2.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 KEY71476.1 - 0.00064 18.8 0.3 0.00064 18.8 0.3 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter TRI12 PF06609.13 KEY71476.1 - 0.026 13.0 1.1 0.04 12.3 1.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Ccdc124 PF06244.12 KEY71477.1 - 5.3e-29 101.4 13.1 2.6e-28 99.2 13.1 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 UQ_con PF00179.26 KEY71477.1 - 3.6e-10 39.6 0.0 1.2e-09 37.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme PfkB PF00294.24 KEY71478.1 - 1.6e-55 188.6 0.1 1.9e-55 188.3 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase p450 PF00067.22 KEY71479.1 - 5e-49 167.3 0.0 7.3e-32 110.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RibD_C PF01872.17 KEY71480.1 - 7.4e-33 114.1 0.0 1.1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain DEAD PF00270.29 KEY71482.1 - 5.4e-43 146.8 0.2 1.1e-42 145.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71482.1 - 4.7e-22 78.4 0.1 3.2e-21 75.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEY71482.1 - 0.0013 18.0 0.2 0.0021 17.3 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEY71482.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DsrH PF04077.12 KEY71482.1 - 0.11 12.7 0.2 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 DsrH like protein INCENP_ARK-bind PF03941.15 KEY71483.1 - 1.3e-20 73.1 0.5 1.3e-20 73.1 0.5 2.6 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region AAA_23 PF13476.6 KEY71483.1 - 7.1 7.1 13.7 9.6 6.6 0.8 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KEY71484.1 - 4.4e-69 232.3 7.4 1.3e-67 227.4 7.4 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEY71484.1 - 4.4e-20 72.1 0.3 4.4e-20 72.1 0.3 3.5 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KEY71484.1 - 9.7e-11 42.5 12.1 9.7e-11 42.5 12.1 6.6 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 KEY71484.1 - 5.4e-09 36.3 3.5 0.0015 18.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system HIP1_clath_bdg PF16515.5 KEY71484.1 - 0.00079 20.0 8.3 0.00079 20.0 8.3 8.8 3 2 3 8 8 8 1 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_29 PF13555.6 KEY71484.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HSBP1 PF06825.12 KEY71484.1 - 0.094 12.6 11.1 0.26 11.2 0.3 3.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2316 PF10078.9 KEY71484.1 - 0.94 9.8 11.5 0.027 14.7 1.2 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) ABC_tran PF00005.27 KEY71484.1 - 4.6 7.8 24.3 1.6 9.2 0.1 5.3 3 2 0 3 3 3 0 ABC transporter MOSC PF03473.17 KEY71485.1 - 5.2e-23 81.5 0.0 7.9e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KEY71485.1 - 6.1e-13 48.7 0.0 1.5e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.8 KEY71487.1 - 5.2e-11 42.0 1.3 7e-10 38.3 0.4 2.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71487.1 - 1.7e-07 31.2 9.7 2.9e-07 30.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.17 KEY71488.1 - 4.5e-23 82.1 0.2 7.5e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KEY71488.1 - 0.12 12.7 3.9 0.31 11.4 3.9 1.7 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 KEY71489.1 - 4.2e-33 114.4 0.5 1.7e-32 112.5 0.5 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KEY71489.1 - 7.5e-06 25.9 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KEY71489.1 - 0.00065 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KEY71489.1 - 0.0011 18.5 0.1 0.33 10.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KEY71489.1 - 0.0017 18.8 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KEY71489.1 - 0.0017 17.4 1.3 0.55 9.2 0.1 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KEY71489.1 - 0.0019 18.0 1.1 0.05 13.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY71489.1 - 0.0033 17.7 0.3 0.38 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEY71489.1 - 0.0044 17.5 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEY71489.1 - 0.021 14.9 1.0 0.17 12.0 0.2 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KEY71489.1 - 0.021 15.3 0.2 0.081 13.4 0.1 1.9 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KEY71489.1 - 0.025 14.4 1.1 1.4 8.6 1.1 2.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KEY71489.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KEY71489.1 - 0.083 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KEY71489.1 - 0.1 11.8 0.1 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin DUF2075 PF09848.9 KEY71489.1 - 0.11 11.7 0.5 0.43 9.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NOT2_3_5 PF04153.18 KEY71490.1 - 5.6e-30 104.1 1.3 8.8e-30 103.5 1.3 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.16 KEY71491.1 - 1.6e-10 40.5 0.0 2.5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KEY71491.1 - 0.057 13.5 1.5 0.12 12.5 1.5 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Ost5 PF05251.12 KEY71491.1 - 0.18 12.1 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 G2BR PF18442.1 KEY71491.1 - 9.8 5.9 14.6 1.2 8.9 9.8 1.9 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Reticulon PF02453.17 KEY71492.1 - 4.7e-33 114.4 3.1 6.7e-33 113.9 3.1 1.2 1 0 0 1 1 1 1 Reticulon RabGAP-TBC PF00566.18 KEY71493.1 - 2.1e-48 164.8 0.0 7.8e-48 163.0 0.0 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1664 PF07889.12 KEY71493.1 - 0.23 11.5 12.9 0.071 13.1 6.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KEY71493.1 - 1.2 8.6 7.4 5.1 6.6 7.4 2.0 1 0 0 1 1 1 0 fzo-like conserved region Plk4_PB2 PF18409.1 KEY71493.1 - 3.5 8.3 5.5 8.1 7.2 0.5 3.1 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Laminin_II PF06009.12 KEY71493.1 - 5.1 7.1 16.2 0.059 13.4 4.2 3.2 3 0 0 3 3 3 0 Laminin Domain II Prp19 PF08606.11 KEY71493.1 - 9.2 6.3 13.0 0.46 10.5 2.0 3.4 3 0 0 3 3 3 0 Prp19/Pso4-like Ion_trans PF00520.31 KEY71494.1 - 1.2e-06 27.9 30.7 2e-06 27.2 30.7 1.3 1 0 0 1 1 1 1 Ion transport protein TAP42 PF04177.12 KEY71496.1 - 6.2e-93 311.4 0.0 7.1e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.8 KEY71496.1 - 0.02 14.5 0.1 0.043 13.4 0.0 1.6 1 1 1 2 2 2 0 KIF-1 binding protein C terminal DNA_topoisoIV PF00521.20 KEY71497.1 - 1.4e-121 406.4 0.1 3.5e-121 405.1 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KEY71497.1 - 2.1e-45 154.1 4.0 2.1e-45 154.1 4.0 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KEY71497.1 - 4.4e-23 81.7 0.7 1.1e-22 80.4 0.7 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KEY71497.1 - 9.3e-13 48.7 0.0 3.1e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KEY71497.1 - 7.6e-08 32.5 0.0 3.5e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KEY71497.1 - 0.0088 15.9 0.2 0.032 14.1 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 KEY71499.1 - 8.2e-05 22.4 13.0 0.11 12.7 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEY71499.1 - 0.0017 18.9 1.8 0.0017 18.9 1.8 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY71499.1 - 0.0056 16.5 8.0 1.9 8.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY71499.1 - 0.045 14.0 0.8 5.8 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY71499.1 - 3.9 7.8 7.8 0.27 11.5 2.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MFS_1 PF07690.16 KEY71500.1 - 2.1e-33 115.7 29.0 7.9e-26 90.8 8.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY71500.1 - 4.5e-12 45.6 9.0 3.1e-11 42.8 1.0 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KEY71500.1 - 0.12 11.2 17.6 0.09 11.6 4.3 3.0 2 1 0 2 2 2 0 MFS_1 like family BT1 PF03092.16 KEY71500.1 - 0.2 9.9 11.5 1.1 7.4 3.1 2.8 3 0 0 3 3 3 0 BT1 family HIT PF01230.23 KEY71501.1 - 1.8e-18 67.1 0.1 2.7e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEY71501.1 - 0.00057 20.3 0.0 0.00082 19.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.16 KEY71502.1 - 1.3e-25 90.1 33.9 5.4e-21 74.9 13.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1751 PF08551.10 KEY71502.1 - 0.012 16.1 0.2 0.86 10.2 0.1 2.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF5326 PF17260.2 KEY71502.1 - 0.03 14.4 0.2 0.03 14.4 0.2 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Myb_Cef PF11831.8 KEY71503.1 - 1.5e-53 181.8 7.4 1.5e-53 181.8 7.4 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KEY71503.1 - 4.1e-22 78.1 4.7 8.6e-11 41.9 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY71503.1 - 5.6e-20 71.4 4.1 1.6e-14 53.9 2.9 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Golgin_A5 PF09787.9 KEY71503.1 - 0.0011 18.5 1.2 0.0011 18.5 1.2 3.6 3 1 0 3 3 3 1 Golgin subfamily A member 5 Nucleo_P87 PF07267.11 KEY71503.1 - 0.0018 17.3 1.2 0.0018 17.3 1.2 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus capsid protein P87 Rap1_C PF11626.8 KEY71503.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 KEY71504.1 - 2.5e-37 128.6 38.2 2.5e-37 128.6 38.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY71504.1 - 2.1e-07 29.8 16.7 7.7e-05 21.3 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Hexokinase_2 PF03727.16 KEY71505.1 - 8.4e-49 166.2 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEY71505.1 - 1.5e-44 152.3 0.0 2.1e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase GILT PF03227.16 KEY71506.1 - 3.9e-19 68.8 0.0 5.9e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PRIMA1 PF16101.5 KEY71506.1 - 0.098 12.7 5.3 0.079 13.0 3.8 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DcpS PF05652.12 KEY71507.1 - 1.9e-32 112.2 0.0 3.2e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KEY71507.1 - 2.5e-32 111.7 0.1 3.7e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_9 PF14604.6 KEY71508.1 - 4.2e-05 23.3 0.1 9.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY71508.1 - 0.00019 20.9 0.1 0.00052 19.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 KEY71508.1 - 0.0004 20.9 0.1 0.0015 19.1 0.1 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SARAF PF06682.12 KEY71508.1 - 0.0022 17.7 2.4 0.0045 16.7 2.4 1.5 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Glycophorin_A PF01102.18 KEY71508.1 - 0.0088 16.3 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 KEY71508.1 - 0.0093 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 KEY71508.1 - 0.013 15.3 0.5 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KEY71508.1 - 0.05 14.5 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5518 PF17647.1 KEY71508.1 - 0.071 13.3 5.2 0.64 10.2 2.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5518) CYYR1 PF10873.8 KEY71508.1 - 0.099 13.1 0.1 0.099 13.1 0.1 2.0 2 0 0 2 2 1 0 Cysteine and tyrosine-rich protein 1 TMEM51 PF15345.6 KEY71508.1 - 0.1 12.5 0.0 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 Syndecan PF01034.20 KEY71508.1 - 0.33 10.9 0.7 0.65 10.0 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KEY71508.1 - 1.3 8.5 5.2 2.5 7.6 5.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3112 PF11309.8 KEY71509.1 - 2.9e-10 40.0 7.6 1e-07 31.6 2.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.28 KEY71510.1 - 8.8e-38 130.9 0.7 1.4e-37 130.2 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEY71510.1 - 0.01 16.3 0.1 0.02 15.3 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KEY71510.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Exo84_C PF16528.5 KEY71511.1 - 2e-77 259.7 0.2 2e-77 259.7 0.2 2.4 4 0 0 4 4 4 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KEY71511.1 - 5.4e-16 58.4 1.8 5.4e-16 58.4 1.8 2.0 2 0 0 2 2 2 1 Vps51/Vps67 DUF2383 PF09537.10 KEY71511.1 - 0.27 11.6 3.5 0.26 11.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) MAS20 PF02064.15 KEY71512.1 - 4.6e-38 130.2 0.2 5.5e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Wyosine_form PF08608.12 KEY71513.1 - 9.2e-26 90.0 0.0 2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KEY71513.1 - 3.3e-23 82.9 0.1 7.9e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KEY71513.1 - 3.8e-10 40.1 0.4 1.1e-07 32.1 0.2 3.4 2 1 0 2 2 2 1 Flavodoxin DNA_pol_alpha_N PF12254.8 KEY71513.1 - 0.017 15.2 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal CDO_I PF05995.12 KEY71514.1 - 4.3e-41 140.0 0.0 5.6e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KEY71514.1 - 0.037 13.5 0.2 0.066 12.7 0.2 1.4 1 1 0 1 1 1 0 PCO_ADO SNF2_N PF00176.23 KEY71515.1 - 1.7e-68 230.9 0.0 2.4e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KEY71515.1 - 3.1e-16 59.1 0.0 8.9e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KEY71515.1 - 3.2e-11 43.6 0.0 9.4e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KEY71515.1 - 5.5e-10 38.9 12.2 1.9e-09 37.2 9.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY71515.1 - 1.9e-08 34.0 11.4 1.9e-08 34.0 11.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY71515.1 - 1.1e-07 31.6 12.6 1.1e-07 31.6 12.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY71515.1 - 1.5e-07 31.6 12.8 1.6e-07 31.5 10.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KEY71515.1 - 2.8e-07 30.4 10.4 2.8e-07 30.4 10.4 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY71515.1 - 7.2e-07 29.1 6.3 9.1e-07 28.8 5.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEY71515.1 - 7.3e-06 26.2 6.3 1.8e-05 24.9 6.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KEY71515.1 - 1.1e-05 25.2 9.7 1.1e-05 25.2 9.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 ResIII PF04851.15 KEY71515.1 - 0.00021 21.3 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_10 PF16685.5 KEY71515.1 - 0.0011 19.1 6.9 0.0031 17.6 6.9 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KEY71515.1 - 0.0012 19.0 9.5 0.0027 17.8 9.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KEY71515.1 - 0.0033 17.3 3.0 0.0033 17.3 3.0 2.2 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KEY71515.1 - 0.0037 17.3 3.2 0.0079 16.2 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KEY71515.1 - 0.068 13.0 7.9 0.17 11.7 7.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rubredoxin_2 PF18073.1 KEY71515.1 - 0.082 12.6 1.5 0.2 11.4 1.5 1.7 1 0 0 1 1 1 0 Rubredoxin metal binding domain zf-P11 PF03854.14 KEY71515.1 - 8.7 6.1 11.1 3.6 7.3 6.4 2.5 2 1 1 3 3 3 0 P-11 zinc finger NCA2 PF08637.10 KEY71516.1 - 3.6e-108 361.1 0.1 5.7e-108 360.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 KEY71517.1 - 8.7e-27 94.1 13.5 8.7e-27 94.1 13.5 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 KEY71518.1 - 9.6e-26 89.8 0.2 1.6e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Trypsin_2 PF13365.6 KEY71521.1 - 1.7e-14 54.9 0.0 2.8e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KEY71521.1 - 3.2e-11 43.5 0.4 6.2e-11 42.5 0.4 1.4 1 0 0 1 1 1 1 Trypsin Transp_cyt_pur PF02133.15 KEY71522.1 - 6.8e-28 97.6 33.7 1.6e-27 96.4 33.7 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_1 PF01979.20 KEY71523.1 - 1.2e-55 189.2 0.2 1.4e-55 189.0 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY71523.1 - 6.1e-15 55.6 0.5 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF3884 PF13024.6 KEY71523.1 - 0.73 9.4 3.2 9.6 5.8 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3884) Fungal_trans_2 PF11951.8 KEY71524.1 - 9.1e-48 163.0 0.1 1.2e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71524.1 - 1.7e-07 31.2 6.9 3.7e-07 30.2 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KEY71525.1 - 1.7e-22 80.1 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY71525.1 - 3.3e-15 56.5 0.0 7.6e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEY71525.1 - 2.1e-06 28.0 0.1 5.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEY71525.1 - 0.00093 18.7 0.0 0.096 12.1 0.0 2.5 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KEY71525.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DNA_meth_N PF18284.1 KEY71525.1 - 0.045 13.7 0.8 0.045 13.7 0.8 2.0 2 0 0 2 2 2 0 DNA methylase N-terminal domain NUDIX PF00293.28 KEY71526.1 - 2.1e-11 44.0 0.1 3.1e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain DUF4189 PF13827.6 KEY71526.1 - 0.09 13.3 0.1 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4189) FAD_binding_4 PF01565.23 KEY71527.1 - 6.1e-22 77.9 0.2 1.2e-21 76.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Sulfotransfer_4 PF17784.1 KEY71528.1 - 7.5e-36 124.0 0.0 1.6e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain p450 PF00067.22 KEY71528.1 - 6.2e-16 58.2 0.0 1.1e-15 57.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Sulfotransfer_3 PF13469.6 KEY71528.1 - 0.00048 20.6 0.3 0.0086 16.5 0.3 2.6 1 1 0 1 1 1 1 Sulfotransferase family ER_lumen_recept PF00810.18 KEY71529.1 - 0.027 15.3 1.6 0.18 12.6 0.1 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor Cellulase PF00150.18 KEY71530.1 - 2.4e-18 66.6 0.9 3.2e-18 66.2 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KEY71530.1 - 9.2e-11 41.5 5.5 9.2e-11 41.5 5.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KEY71530.1 - 3.5e-05 23.1 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KEY71530.1 - 3.5e-05 23.6 0.4 5.2e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KEY71530.1 - 0.0066 15.8 0.9 0.02 14.3 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.14 KEY71531.1 - 3.7e-42 145.1 0.1 4.8e-42 144.7 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase Glyco_hydro_61 PF03443.14 KEY71532.1 - 9.6e-61 205.3 0.0 1.1e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 KEY71533.1 - 1.4e-20 73.6 0.0 3.5e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71533.1 - 5.8e-10 39.1 0.0 4.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71533.1 - 1.2e-06 28.6 0.1 3.3e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KEY71533.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 KEY71534.1 - 4.9e-09 36.2 6.9 1e-08 35.1 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY71535.1 - 1.2e-16 60.6 1.1 4.3e-09 35.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71535.1 - 8.2e-05 22.6 8.3 0.00015 21.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KEY71536.1 - 1e-112 376.8 0.0 1.2e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KEY71537.1 - 2.1e-134 448.5 0.0 2.4e-134 448.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEY71537.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 KEY71538.1 - 6e-179 595.4 1.1 6.8e-179 595.2 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.18 KEY71539.1 - 5.7e-06 26.4 8.9 1e-05 25.5 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY71540.1 - 7.4e-19 67.8 1.8 9.9e-19 67.4 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KEY71541.1 - 1.7e-34 120.0 1.3 1.9e-34 119.8 1.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY71541.1 - 1.6e-06 27.6 0.3 3.1e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 KEY71541.1 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KEY71541.1 - 0.0013 18.9 1.8 0.0035 17.5 1.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY71541.1 - 0.0054 15.8 0.4 0.021 13.9 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY71541.1 - 0.0075 15.5 0.2 0.019 14.2 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY71541.1 - 0.0078 15.5 1.0 0.017 14.4 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY71541.1 - 0.033 13.5 2.0 0.041 13.2 1.7 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEY71541.1 - 0.059 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KEY71541.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KEY71541.1 - 0.25 10.4 6.1 1.6 7.7 6.1 2.0 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KEY71541.1 - 0.34 9.5 1.0 12 4.5 0.8 2.1 2 0 0 2 2 2 0 HI0933-like protein Amidase PF01425.21 KEY71542.1 - 6e-82 276.0 0.0 8.3e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Amidase AA_permease_2 PF13520.6 KEY71543.1 - 8.9e-29 100.6 39.3 6.6e-24 84.5 20.6 2.1 1 1 1 2 2 2 2 Amino acid permease ADH_N_2 PF16884.5 KEY71544.1 - 2e-26 92.0 0.2 3.5e-26 91.2 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY71544.1 - 3.7e-08 33.4 0.0 7.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF3182 PF11379.8 KEY71545.1 - 0.054 12.5 0.0 0.066 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) SNF2_N PF00176.23 KEY71548.1 - 0.0011 17.7 0.0 0.013 14.2 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Ribosomal_S14 PF00253.21 KEY71549.1 - 0.083 12.7 0.9 1.1 9.0 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Retrotran_gag_2 PF14223.6 KEY71549.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HET PF06985.11 KEY71550.1 - 2.9e-08 34.2 2.9 3.8e-06 27.3 0.8 2.3 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY71551.1 - 1.1e-95 314.3 4.5 2.8e-16 59.9 0.2 8.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY71551.1 - 1.6e-76 251.4 0.3 3.6e-09 36.7 0.0 13.7 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY71551.1 - 3.5e-72 237.9 0.2 8.6e-12 45.3 0.0 10.3 7 1 3 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KEY71551.1 - 4.4e-69 226.1 2.1 2e-05 24.8 0.0 15.4 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 KEY71551.1 - 4.6e-59 189.4 0.0 0.002 18.5 0.0 15.3 15 0 0 15 15 15 12 Ankyrin repeat DUF1843 PF08898.10 KEY71551.1 - 0.0015 19.0 24.5 2.4 8.7 0.2 7.2 7 0 0 7 7 7 3 Domain of unknown function (DUF1843) DUF2520 PF10728.9 KEY71551.1 - 0.0018 18.0 4.5 0.37 10.5 2.8 4.4 2 1 1 3 3 3 1 Domain of unknown function (DUF2520) Phage_T7_Capsid PF05396.11 KEY71551.1 - 0.034 14.5 1.9 49 4.3 0.1 3.9 1 1 2 3 3 3 0 Phage T7 capsid assembly protein Nuc_rec_co-act PF08815.10 KEY71552.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear receptor coactivator Nnf1 PF03980.14 KEY71555.1 - 5.9e-36 123.2 2.6 2.3e-35 121.3 0.9 2.1 2 0 0 2 2 2 1 Nnf1 DUF1908 PF08926.11 KEY71555.1 - 0.011 14.9 0.0 0.75 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF16 PF01519.16 KEY71555.1 - 0.017 15.6 0.9 1.3 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 RmuC PF02646.16 KEY71555.1 - 0.022 13.9 1.3 0.033 13.3 0.2 1.6 2 0 0 2 2 2 0 RmuC family Katanin_con80 PF13925.6 KEY71555.1 - 0.12 12.4 1.5 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 con80 domain of Katanin Rootletin PF15035.6 KEY71555.1 - 0.29 11.1 4.3 1.8 8.5 4.3 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.11 KEY71555.1 - 0.4 11.3 3.8 1.8 9.2 1.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FliJ PF02050.16 KEY71555.1 - 0.93 9.7 9.0 0.16 12.2 2.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein SlyX PF04102.12 KEY71555.1 - 5.7 7.6 13.1 0.91 10.2 3.2 3.0 2 2 0 2 2 2 0 SlyX PH_9 PF15410.6 KEY71556.1 - 9.9e-05 22.7 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Chromo PF00385.24 KEY71557.1 - 0.0064 16.4 0.2 1.1 9.2 0.0 2.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain G-alpha PF00503.20 KEY71559.1 - 5.6e-48 163.9 0.0 8.1e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEY71559.1 - 0.00014 21.3 0.0 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KEY71559.1 - 0.0042 17.5 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KEY71559.1 - 0.0055 17.2 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KEY71559.1 - 0.0065 16.9 0.0 0.032 14.6 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY71559.1 - 0.0093 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEY71559.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY71559.1 - 0.022 15.3 0.1 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEY71559.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 KEY71559.1 - 0.043 13.0 0.0 0.073 12.2 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KEY71559.1 - 0.044 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY71559.1 - 0.075 13.3 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEY71559.1 - 0.096 13.1 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DAP3 PF10236.9 KEY71559.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.32 KEY71560.1 - 6.9e-190 609.0 39.0 2.8e-11 43.8 0.0 21.5 21 0 0 21 21 21 21 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71560.1 - 1e-63 211.6 16.2 0.00091 19.5 0.0 18.7 3 2 13 17 17 17 15 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY71560.1 - 5.9e-48 163.8 63.3 0.0044 15.7 0.1 18.7 5 4 12 19 19 19 17 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEY71560.1 - 7e-31 107.4 36.3 0.00062 18.8 0.2 13.1 2 2 13 15 15 15 13 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KEY71560.1 - 1.3e-11 43.6 2.0 0.083 11.4 0.0 6.4 2 2 4 8 8 8 5 Cytochrome D1 heme domain NACHT PF05729.12 KEY71560.1 - 3.3e-09 36.9 0.0 6.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain BLUF PF04940.12 KEY71560.1 - 4.4e-09 36.3 8.9 15 5.8 0.0 11.9 9 4 5 14 14 14 0 Sensors of blue-light using FAD DUF4585 PF15232.6 KEY71560.1 - 3.2e-08 33.5 0.0 44 4.2 0.0 11.6 12 1 2 15 15 15 0 Domain of unknown function (DUF4585) AAA_16 PF13191.6 KEY71560.1 - 3.8e-07 30.6 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Nucleoporin_N PF08801.11 KEY71560.1 - 2.1e-05 23.5 14.0 1.6 7.4 0.2 9.1 8 3 2 10 10 10 1 Nup133 N terminal like Helo_like_N PF17111.5 KEY71560.1 - 0.00011 21.6 1.3 0.0003 20.2 0.2 2.5 2 0 0 2 2 1 1 Fungal N-terminal domain of STAND proteins DUF1854 PF08909.11 KEY71560.1 - 0.00032 20.5 10.6 16 5.3 0.1 10.0 7 6 5 12 12 12 0 Domain of unknown function (DUF1854) PD40 PF07676.12 KEY71560.1 - 0.0017 18.2 10.6 97 3.1 0.0 9.9 12 0 0 12 12 11 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 KEY71560.1 - 0.0025 18.0 1.9 17 5.6 0.0 6.0 6 2 2 8 8 7 0 Siderophore-interacting FAD-binding domain DUF3037 PF11236.8 KEY71560.1 - 0.0085 16.5 1.0 19 5.7 0.0 5.2 5 1 1 6 6 5 0 Protein of unknown function (DUF3037) PIF1 PF05970.14 KEY71560.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KEY71560.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RAB3GAP2_N PF14655.6 KEY71560.1 - 0.022 14.0 4.1 14 4.8 0.0 5.6 3 1 2 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_18 PF13238.6 KEY71560.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEY71560.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KEY71560.1 - 0.057 13.8 0.2 0.29 11.6 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) WD40_like PF17005.5 KEY71560.1 - 0.12 11.7 0.0 77 2.5 0.0 4.5 4 2 1 6 6 6 0 WD40-like domain RNA_helicase PF00910.22 KEY71560.1 - 0.19 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KEY71560.1 - 0.23 10.7 2.2 1.4 8.1 0.3 2.4 1 1 0 2 2 2 0 KAP family P-loop domain CXCXC PF03128.14 KEY71560.1 - 0.23 12.0 11.2 4.5 7.9 2.2 4.0 2 0 0 2 2 2 0 CXCXC repeat IU_nuc_hydro PF01156.19 KEY71561.1 - 3e-10 40.1 0.0 6.1e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF416 PF04222.12 KEY71561.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DUF1593 PF07632.11 KEY71561.1 - 0.16 11.4 0.3 1.1 8.6 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1593) BLYB PF05289.11 KEY71561.1 - 0.3 11.3 2.2 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein Glycolipid_bind PF06475.11 KEY71562.1 - 0.064 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative glycolipid-binding Oxygenase-NA PF09859.9 KEY71562.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA F-box-like PF12937.7 KEY71562.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF2695 PF10905.8 KEY71563.1 - 0.02 15.1 0.2 0.035 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Con-6 PF10346.9 KEY71563.1 - 0.88 9.6 3.8 0.4 10.7 1.1 1.9 2 0 0 2 2 2 0 Conidiation protein 6 ADH_zinc_N PF00107.26 KEY71564.1 - 3e-07 30.5 0.0 4.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY71564.1 - 7.1e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY71564.1 - 0.16 13.0 0.0 0.42 11.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Syndecan PF01034.20 KEY71565.1 - 0.0047 16.8 0.2 0.0089 15.9 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain Prim-Pol PF09250.11 KEY71566.1 - 0.013 15.8 1.1 0.02 15.3 1.1 1.2 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DUF2268 PF10026.9 KEY71566.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PGAP1 PF07819.13 KEY71567.1 - 6.4e-06 26.1 0.2 5.5e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEY71567.1 - 0.00084 20.0 0.2 0.00084 20.0 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY71567.1 - 0.0028 17.0 0.0 0.0072 15.6 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KEY71567.1 - 0.003 17.1 0.0 0.0079 15.7 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DDHD PF02862.17 KEY71567.1 - 0.22 11.7 12.3 0.091 12.9 9.8 1.6 2 0 0 2 2 2 0 DDHD domain V_ATPase_I PF01496.19 KEY71567.1 - 0.33 8.8 9.1 0.46 8.3 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAF-1_p150 PF11600.8 KEY71567.1 - 0.35 10.6 36.0 0.57 9.9 36.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 KEY71567.1 - 0.69 9.7 14.8 1.1 9.0 14.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 KEY71567.1 - 1.2 9.2 17.8 1.9 8.5 17.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.9 KEY71567.1 - 1.3 8.6 34.4 3 7.4 34.4 1.5 1 0 0 1 1 1 0 DDRGK domain PA26 PF04636.13 KEY71567.1 - 1.4 7.7 9.1 2.2 7.1 9.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 KEY71567.1 - 2.2 8.0 13.6 3.7 7.2 13.6 1.3 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KEY71567.1 - 5.1 5.6 16.4 8.9 4.8 16.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Presenilin PF01080.17 KEY71567.1 - 6.3 5.5 18.7 10 4.8 18.7 1.2 1 0 0 1 1 1 0 Presenilin DUF853 PF05872.12 KEY71567.1 - 8.2 4.9 13.6 12 4.3 13.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Plasmodium_Vir PF05795.11 KEY71567.1 - 9.7 5.5 10.9 17 4.7 10.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HET PF06985.11 KEY71568.1 - 5.5e-08 33.3 0.0 1.5e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KEY71569.1 - 1.9e-15 56.4 0.0 1.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.29 KEY71570.1 - 4.8e-47 160.0 0.0 1.1e-46 158.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71570.1 - 1.3e-30 106.0 0.0 2.9e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY71570.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KEY71570.1 - 0.12 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.26 KEY71571.1 - 1.6e-38 132.1 0.0 1.9e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 KEY71572.1 - 2e-22 79.0 6.2 9.4e-06 26.3 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71572.1 - 0.0085 16.4 0.0 0.55 10.6 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KEY71572.1 - 0.029 14.4 0.0 15 5.7 0.1 3.5 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF885 PF05960.11 KEY71572.1 - 0.029 14.0 1.6 0.041 13.5 1.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) WD40_like PF17005.5 KEY71572.1 - 0.086 12.1 0.0 0.65 9.3 0.0 2.4 3 1 0 3 3 3 0 WD40-like domain DUF4692 PF15763.5 KEY71572.1 - 0.22 12.0 5.6 0.49 10.8 5.6 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Peptidase_C48 PF02902.19 KEY71573.1 - 3.6e-32 112.0 0.0 6.7e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.12 KEY71574.1 - 5.1e-42 143.2 3.1 7.9e-41 139.4 3.1 2.0 1 1 0 1 1 1 1 Signal peptidase subunit XRN_M PF17846.1 KEY71575.1 - 3.6e-98 329.4 5.9 5.9e-98 328.7 5.9 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KEY71575.1 - 1.7e-96 322.3 0.0 2.7e-96 321.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KEY71575.1 - 4.4e-71 238.6 0.0 8.1e-71 237.8 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KEY71575.1 - 3.3e-35 120.2 0.0 8.6e-35 118.8 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KEY71575.1 - 5.5e-19 68.0 0.1 1.1e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KEY71575.1 - 5.8e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DsrD PF08679.11 KEY71575.1 - 0.013 15.7 2.1 0.13 12.6 0.3 2.8 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Sterile PF03015.19 KEY71575.1 - 0.096 12.9 0.1 0.54 10.5 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein Phage_Arf PF17585.2 KEY71575.1 - 0.2 11.6 1.2 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 Accessory recombination function protein WD40 PF00400.32 KEY71576.1 - 5.7e-28 96.6 3.8 2.7e-06 28.0 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KEY71576.1 - 6.9e-27 93.5 0.2 7.1e-26 90.3 0.2 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KEY71576.1 - 6.2e-06 26.4 1.6 0.029 14.6 0.1 4.6 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RanBP PF00641.18 KEY71578.1 - 2.1e-18 65.3 13.4 6.1e-11 41.4 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KEY71578.1 - 2.8e-08 33.4 0.0 6.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KEY71578.1 - 5.9e-07 30.2 0.0 8.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease ORC2 PF04084.14 KEY71578.1 - 0.28 10.1 0.1 0.42 9.5 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Pmp3 PF01679.17 KEY71579.1 - 1.1e-20 73.6 10.0 1.3e-20 73.3 10.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KEY71579.1 - 0.32 10.6 2.7 0.48 10.0 2.7 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Pkinase PF00069.25 KEY71581.1 - 1.6e-69 234.2 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71581.1 - 5.1e-36 124.3 0.0 8.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71581.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY71581.1 - 0.0021 17.5 0.1 0.0044 16.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEY71581.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KEY71581.1 - 0.12 11.3 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KEY71581.1 - 0.15 10.8 0.0 0.15 10.8 0.0 2.4 2 1 0 2 2 2 0 Fungal protein kinase Abhydrolase_1 PF00561.20 KEY71582.1 - 6.2e-11 42.4 0.0 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY71582.1 - 6.4e-08 32.1 0.0 4.8e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1764 PF08576.10 KEY71583.1 - 3.7 8.5 21.0 2 9.4 1.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) IF4E PF01652.18 KEY71584.1 - 1e-52 178.1 0.0 1.4e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UCH PF00443.29 KEY71585.1 - 3.1e-27 95.7 0.0 4.6e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KEY71585.1 - 4.4e-12 46.1 0.1 4.4e-12 46.1 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KEY71585.1 - 0.00014 21.6 0.1 0.0017 18.0 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 KEY71585.1 - 0.08 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) Utp13 PF08625.11 KEY71586.1 - 2e-51 173.6 0.1 3.1e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KEY71586.1 - 4.4e-44 147.6 40.7 6.5e-05 23.6 0.6 11.7 10 2 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71586.1 - 3.7e-13 49.6 6.7 0.012 15.8 0.1 7.7 6 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY71586.1 - 9.4e-05 21.2 4.2 1.1 7.9 0.0 5.2 3 2 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEY71586.1 - 0.053 12.3 9.9 0.72 8.5 0.1 4.6 3 3 1 5 5 5 0 Nup133 N terminal like zf-Nse PF11789.8 KEY71588.1 - 3.3e-19 68.4 0.2 5.4e-19 67.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KEY71588.1 - 0.0024 17.6 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 KEY71588.1 - 0.0092 16.0 0.4 0.018 15.1 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY71588.1 - 0.17 11.7 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40_alt PF14077.6 KEY71588.1 - 0.49 10.3 3.2 0.7 9.8 1.4 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif Methyltransf_23 PF13489.6 KEY71589.1 - 1.2e-20 74.0 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71589.1 - 9e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71589.1 - 4.7e-15 56.1 0.0 8.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71589.1 - 1.2e-13 51.2 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71589.1 - 5.7e-13 49.4 0.0 8.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEY71589.1 - 4.6e-05 22.9 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KEY71589.1 - 0.00053 19.0 0.0 0.00077 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KEY71589.1 - 0.0037 16.6 0.0 0.0083 15.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KEY71589.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DHBP_synthase PF00926.19 KEY71590.1 - 4.5e-78 261.2 0.0 5.1e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Atx10homo_assoc PF09759.9 KEY71591.1 - 3.2e-12 46.3 0.0 9.8e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.20 KEY71592.1 - 7.6e-43 146.4 0.1 9.1e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_33 PF10017.9 KEY71593.1 - 1.8e-77 260.5 0.0 2.2e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.8 KEY71594.1 - 7.7e-19 67.8 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MDM31_MDM32 PF08118.11 KEY71595.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DAO PF01266.24 KEY71596.1 - 8.6e-32 111.1 0.1 2e-31 109.9 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY71596.1 - 1.1e-05 24.9 0.0 0.00022 20.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KEY71596.1 - 0.00017 21.1 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_7 PF13241.6 KEY71596.1 - 0.00017 21.9 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KEY71596.1 - 0.00018 21.5 0.0 0.72 9.8 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KEY71596.1 - 0.00018 20.5 0.1 0.0019 17.2 0.1 2.0 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KEY71596.1 - 0.00043 20.5 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY71596.1 - 0.0032 18.0 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY71596.1 - 0.0067 15.6 5.0 0.83 8.7 5.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY71596.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEY71596.1 - 0.033 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KEY71596.1 - 0.037 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KEY71596.1 - 0.071 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KEY71596.1 - 0.074 12.1 0.1 4.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KEY71596.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEY71596.1 - 0.1 12.0 0.5 0.26 10.6 0.3 1.7 2 0 0 2 2 2 0 ThiF family NAD_Gly3P_dh_N PF01210.23 KEY71596.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KEY71596.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEY71596.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KEY71596.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_1 PF00667.20 KEY71597.1 - 7.2e-62 208.8 0.0 1.8e-61 207.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KEY71597.1 - 1.1e-09 38.9 0.0 3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KEY71597.1 - 1.3e-08 35.1 0.3 4.6e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 KEY71597.1 - 1.4e-06 28.5 0.1 3.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 KEY71597.1 - 0.00019 21.3 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain HAD_2 PF13419.6 KEY71600.1 - 2.9e-06 27.5 0.0 4.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY71600.1 - 0.023 14.7 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2608 PF11019.8 KEY71600.1 - 0.025 14.1 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) adh_short PF00106.25 KEY71600.1 - 0.04 13.4 0.0 0.099 12.1 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Hydrolase PF00702.26 KEY71600.1 - 0.068 13.4 0.1 1.2 9.4 0.1 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 KEY71601.1 - 2.2e-24 86.1 0.1 1.5e-23 83.3 0.1 1.9 1 1 1 2 2 2 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KEY71602.1 - 2.2e-47 160.9 0.5 4.6e-47 159.9 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEY71602.1 - 1.7e-34 119.9 0.2 3e-34 119.2 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEY71602.1 - 1.4e-21 76.7 0.0 1.4e-11 44.6 0.0 3.9 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KEY71602.1 - 4.6e-06 26.6 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY71602.1 - 0.0053 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KEY71602.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat Cyclin_N PF00134.23 KEY71603.1 - 3.2e-13 49.6 0.0 5.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KEY71603.1 - 1.1e-07 32.3 1.5 2.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin RAP1 PF07218.11 KEY71603.1 - 10 4.3 8.7 13 3.9 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KEY71605.1 - 1.9e-70 237.3 0.0 3e-70 236.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71605.1 - 3.9e-32 111.6 0.0 4.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY71605.1 - 0.0004 19.4 0.1 0.021 13.8 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KEY71605.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KEY71605.1 - 0.0091 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY71605.1 - 0.055 12.8 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0029 PF01205.19 KEY71606.1 - 4.5e-28 97.7 0.0 1.3e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF4629 PF15442.6 KEY71606.1 - 0.26 11.5 4.9 0.37 11.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) DUF2877 PF11392.8 KEY71606.1 - 0.52 11.0 3.7 0.26 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Methyltransf_23 PF13489.6 KEY71607.1 - 9.4e-18 64.6 0.0 2e-17 63.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71607.1 - 2.5e-05 24.9 0.0 0.027 15.2 0.0 3.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71607.1 - 4e-05 24.2 0.0 0.0031 18.1 0.0 3.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71607.1 - 0.00051 20.7 0.0 0.0054 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71607.1 - 0.0052 16.6 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71607.1 - 0.0061 15.9 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family TFIIF_alpha PF05793.12 KEY71608.1 - 0.2 10.2 2.6 0.39 9.2 2.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PhzC-PhzF PF02567.16 KEY71609.1 - 6e-36 124.4 0.0 1.4e-35 123.2 0.0 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Not1 PF04054.15 KEY71610.1 - 4.8e-120 400.9 0.0 1.1e-119 399.6 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KEY71610.1 - 3.3e-93 311.2 1.4 7.3e-93 310.1 1.4 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KEY71610.1 - 1.1e-48 164.9 1.6 1.1e-48 164.9 1.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KEY71610.1 - 1e-42 145.5 0.0 3.4e-42 143.8 0.0 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KEY71610.1 - 4.5e-33 114.5 0.1 1.5e-32 112.7 0.1 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CSTF2_hinge PF14327.6 KEY71610.1 - 0.011 16.1 0.0 0.058 13.8 0.0 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 FCH PF00611.23 KEY71611.1 - 1.5e-15 57.2 0.1 7.1e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KEY71611.1 - 8.3e-12 44.8 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEY71611.1 - 1.9e-11 43.4 0.0 3.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEY71611.1 - 1.3e-10 40.8 0.5 5.3e-10 38.8 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain SHE3 PF17078.5 KEY71611.1 - 0.17 11.6 5.4 0.033 13.9 1.0 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Seipin PF06775.14 KEY71612.1 - 5e-42 144.3 0.0 6.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SOCS PF12610.8 KEY71612.1 - 1.7 9.1 3.6 2.5 8.5 2.5 1.8 2 0 0 2 2 2 0 Suppressor of cytokine signalling zf-LITAF-like PF10601.9 KEY71613.1 - 1.9e-15 56.9 1.2 2.6e-15 56.4 1.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Nup84_Nup100 PF04121.13 KEY71615.1 - 1.3e-183 612.1 0.1 1.4e-183 611.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 MTCP1 PF08991.10 KEY71617.1 - 1.4e-29 102.1 8.8 1.6e-29 101.9 8.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KEY71617.1 - 0.027 14.6 5.8 0.027 14.6 5.8 1.6 2 0 0 2 2 2 0 CHCH domain PIP49_C PF12260.8 KEY71617.1 - 0.04 13.6 4.4 0.041 13.5 4.4 1.0 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Rad60-SLD PF11976.8 KEY71618.1 - 1.2e-18 66.7 0.1 1.4e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEY71618.1 - 7.5e-11 41.6 0.1 1.1e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.18 KEY71618.1 - 0.02 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain LIM PF00412.22 KEY71619.1 - 7.2e-25 87.0 24.5 1.9e-08 34.4 6.2 3.4 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 KEY71619.1 - 0.027 14.1 0.3 0.027 14.1 0.3 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 KEY71619.1 - 0.24 11.4 13.0 4.1 7.4 1.2 5.7 5 0 0 5 5 5 0 Nudix N-terminal DZR PF12773.7 KEY71619.1 - 0.63 10.1 26.1 9.5 6.3 9.0 4.3 1 1 2 3 3 3 0 Double zinc ribbon CHCH PF06747.13 KEY71620.1 - 1.3e-05 25.2 0.9 2.8e-05 24.1 0.9 1.6 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KEY71620.1 - 0.003 17.6 1.5 0.0039 17.2 1.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KEY71620.1 - 0.011 16.1 3.4 0.04 14.2 3.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KEY71620.1 - 0.025 14.9 3.9 0.47 10.8 0.6 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 KEY71620.1 - 0.035 14.5 1.9 0.053 14.0 1.9 1.2 1 0 0 1 1 1 0 GCK domain Dynamin_M PF01031.20 KEY71621.1 - 2e-109 365.2 0.0 4e-109 364.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KEY71621.1 - 4.3e-57 192.8 0.0 9.1e-57 191.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KEY71621.1 - 8.3e-31 106.0 2.1 8.3e-31 106.0 2.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEY71621.1 - 3.6e-05 23.8 0.2 0.00052 20.1 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase F-box PF00646.33 KEY71622.1 - 0.06 13.3 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain zf-Di19 PF05605.12 KEY71622.1 - 1.8 8.9 4.2 1.8 8.9 0.1 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Fungal_trans PF04082.18 KEY71623.1 - 2.4e-12 46.5 0.7 4.3e-12 45.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glutaredoxin PF00462.24 KEY71624.1 - 1.1e-18 67.1 0.0 1.9e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KEY71624.1 - 5.4e-12 45.6 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KEY71624.1 - 0.0077 16.1 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Phosducin PF02114.16 KEY71624.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin SH3_9 PF14604.6 KEY71625.1 - 3.4e-27 94.1 4.6 4.8e-13 48.7 0.5 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KEY71625.1 - 9.3e-24 82.8 4.6 1.9e-11 43.4 0.3 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KEY71625.1 - 4.5e-14 52.3 0.0 9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KEY71625.1 - 7.4e-14 51.2 0.1 3e-06 26.8 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain CYSTM PF12734.7 KEY71627.1 - 1.1e-09 38.5 19.5 1.1e-09 38.5 19.5 4.8 2 1 2 4 4 4 1 Cysteine-rich TM module stress tolerance DUF2321 PF10083.9 KEY71628.1 - 0.064 12.9 0.9 0.12 12.0 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) C1_2 PF03107.16 KEY71628.1 - 0.19 12.1 5.5 0.39 11.1 5.5 1.5 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 KEY71628.1 - 0.26 11.5 3.7 0.54 10.5 3.7 1.5 1 0 0 1 1 1 0 B-box zinc finger eIF-3_zeta PF05091.12 KEY71629.1 - 1.8e-207 690.5 0.0 2.2e-207 690.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KEY71629.1 - 0.01 15.5 0.1 0.027 14.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF569) ArlS_N PF18719.1 KEY71629.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 ArlS sensor domain ICMT PF04140.14 KEY71630.1 - 3.4e-07 30.6 0.1 9.1e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KEY71630.1 - 4.5e-05 23.8 0.6 0.00018 21.8 0.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase Trypan_PARP PF05887.11 KEY71631.1 - 0.0014 18.6 33.3 0.0014 18.6 33.3 16.1 10 3 7 17 17 17 4 Procyclic acidic repetitive protein (PARP) Tristanin_u2 PF16638.5 KEY71632.1 - 0.45 11.4 2.8 0.92 10.3 2.8 1.5 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers zf-C2H2 PF00096.26 KEY71634.1 - 2.4e-13 49.7 12.5 3.7e-06 27.1 2.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY71634.1 - 5.9e-10 39.1 17.6 1.9e-07 31.2 0.2 4.0 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEY71634.1 - 6.5e-09 35.9 11.5 0.00042 20.9 1.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEY71634.1 - 1.7e-08 34.2 5.9 0.00033 20.6 0.3 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEY71634.1 - 1.2e-06 28.6 0.3 0.09 13.1 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY71634.1 - 0.0014 18.9 6.9 0.014 15.8 0.2 3.6 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KEY71634.1 - 0.078 13.3 1.9 0.21 11.9 1.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KEY71634.1 - 0.12 12.2 9.7 0.42 10.4 0.7 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KEY71634.1 - 0.14 12.7 0.8 0.33 11.5 0.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KEY71634.1 - 0.25 11.8 2.4 5.8 7.4 0.4 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KEY71634.1 - 0.8 10.0 3.4 16 5.8 0.1 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KEY71634.1 - 1.8 8.8 4.6 3.2 7.9 4.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 KEY71634.1 - 4.7 7.4 6.9 27 5.0 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain AOX PF01786.17 KEY71635.1 - 1e-89 299.8 0.1 1.3e-89 299.4 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase tRNA-synt_1d PF00750.19 KEY71636.1 - 5.8e-98 328.0 1.0 7.9e-98 327.6 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEY71636.1 - 7.2e-28 97.2 0.2 1.5e-27 96.2 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KEY71636.1 - 6.8e-05 23.4 0.0 0.00016 22.2 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain eIF3_subunit PF08597.10 KEY71637.1 - 6.3e-73 245.6 30.7 7.8e-73 245.3 30.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.11 KEY71637.1 - 0.11 11.8 28.6 0.16 11.4 20.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PRP4 PF08799.11 KEY71637.1 - 1.6 8.3 9.5 1.7 8.3 5.3 2.9 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like MDM31_MDM32 PF08118.11 KEY71638.1 - 1.3e-250 832.6 0.0 1.5e-250 832.4 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 KEY71638.1 - 0.021 14.5 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 TraH_2 KH_8 PF17903.1 KEY71639.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KEY71639.1 - 0.01 15.6 0.4 0.022 14.6 0.4 1.5 1 0 0 1 1 1 0 KH domain Enolase_C PF00113.22 KEY71640.1 - 7.4e-153 508.0 0.1 9.6e-153 507.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KEY71640.1 - 5.3e-58 194.9 0.2 1e-57 194.0 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KEY71640.1 - 5.8e-06 26.0 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KEY71640.1 - 0.044 12.9 0.3 0.54 9.4 0.1 2.4 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus DNA_ligase_aden PF01653.18 KEY71640.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Mad3_BUB1_I PF08311.12 KEY71641.1 - 1.9e-44 150.6 0.1 1.3e-43 147.9 0.2 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KEY71641.1 - 3.5e-09 36.7 0.0 2e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KEY71641.1 - 1.1e-08 34.8 0.0 6.2e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71641.1 - 7.7e-05 22.1 0.0 0.00046 19.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71641.1 - 0.042 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KEY71641.1 - 0.078 12.9 0.2 0.2 11.5 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family AP_endonuc_2 PF01261.24 KEY71642.1 - 4.8e-34 117.6 0.6 6.8e-34 117.2 0.6 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAGAT PF03982.13 KEY71643.1 - 3.6e-89 298.6 0.0 4.7e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.6 KEY71644.1 - 3.8e-11 42.9 17.5 2.7e-06 27.6 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KEY71644.1 - 9.4e-10 38.4 23.1 0.0021 18.4 8.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY71644.1 - 9.9e-06 26.0 19.6 0.02 15.7 6.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger PKcGMP_CC PF16808.5 KEY71644.1 - 0.0078 16.0 0.2 0.0078 16.0 0.2 2.0 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Rad50_zn_hook PF04423.14 KEY71644.1 - 0.037 13.9 0.4 0.11 12.3 0.4 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 KEY71644.1 - 0.055 13.8 10.2 0.95 9.8 3.8 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 KEY71644.1 - 0.12 12.5 2.1 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain bZIP_1 PF00170.21 KEY71644.1 - 0.29 11.3 0.1 0.29 11.3 0.1 1.7 2 0 0 2 2 1 0 bZIP transcription factor zf-C2H2_6 PF13912.6 KEY71644.1 - 0.53 10.4 18.4 0.59 10.2 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KEY71644.1 - 1.1 9.2 3.5 3 7.8 0.4 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KEY71644.1 - 1.2 9.1 5.7 0.76 9.8 0.5 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KEY71644.1 - 1.6 8.8 11.0 1.2 9.2 5.6 2.5 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KEY71644.1 - 2 8.6 5.8 12 6.1 1.7 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KEY71644.1 - 2.7 8.1 6.7 25 5.0 6.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 KEY71644.1 - 3.1 8.2 10.9 0.47 10.8 6.4 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KEY71644.1 - 8.7 6.1 10.3 0.39 10.4 0.7 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-U1 PF06220.12 KEY71645.1 - 0.38 10.6 1.2 0.58 10.0 1.2 1.3 1 0 0 1 1 1 0 U1 zinc finger DUF3425 PF11905.8 KEY71646.1 - 1.7e-14 53.9 0.0 3.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KEY71646.1 - 3e-10 39.9 0.0 9.6e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71646.1 - 1.8e-08 34.2 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 KEY71647.1 - 8e-56 189.2 0.1 1.1e-55 188.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY71647.1 - 4.6e-50 169.8 0.1 5.9e-50 169.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY71647.1 - 2.7e-06 27.4 1.2 3.2e-05 23.9 1.2 2.0 1 1 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KEY71648.1 - 2.6e-09 36.4 0.1 8e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEY71650.1 - 5.8e-79 266.1 26.9 7e-79 265.8 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71650.1 - 8e-27 94.1 53.0 7.3e-25 87.6 32.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_10 PF13374.6 KEY71651.1 - 1.3e-24 85.3 0.1 7e-12 44.8 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY71651.1 - 3.7e-18 65.6 0.1 1.2e-10 41.5 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY71651.1 - 3.6e-09 36.0 0.1 0.00077 19.3 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY71651.1 - 6.8e-06 25.7 0.1 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY71651.1 - 1.6e-05 24.9 0.3 0.078 13.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY71651.1 - 2e-05 24.4 0.1 0.014 15.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY71651.1 - 0.0067 16.9 0.1 0.12 12.9 0.0 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.7 KEY71651.1 - 0.012 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_8 PF13181.6 KEY71651.1 - 0.022 15.0 0.1 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY71651.1 - 0.022 15.4 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY71651.1 - 0.16 12.7 0.0 11 7.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PLA2_B PF01735.18 KEY71652.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain WD40 PF00400.32 KEY71653.1 - 5.1e-25 87.3 9.8 3.6e-12 46.6 0.5 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71653.1 - 8.4e-10 38.8 0.1 0.00026 21.2 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY71653.1 - 3.7e-05 22.8 0.3 0.045 12.7 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEY71653.1 - 0.0014 17.4 0.0 0.54 8.8 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEY71653.1 - 0.0038 15.8 0.0 0.0067 15.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome D1 heme domain Big_7 PF17957.1 KEY71653.1 - 0.033 14.9 1.9 2.2 9.1 0.2 2.5 1 1 1 2 2 2 0 Bacterial Ig domain WD40_like PF17005.5 KEY71653.1 - 0.15 11.3 0.1 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain DPPIV_N PF00930.21 KEY71654.1 - 5.8e-53 179.9 0.0 8.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KEY71654.1 - 2.3e-43 148.1 0.3 3.9e-43 147.4 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KEY71654.1 - 5e-05 23.1 0.3 0.00021 21.1 0.1 2.1 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 KEY71654.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KEY71654.1 - 0.015 14.5 0.1 0.065 12.5 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KEY71654.1 - 0.016 15.1 0.1 0.53 10.2 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KEY71654.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) K1 PF02960.14 KEY71656.1 - 0.053 13.6 3.6 1.3 9.1 0.5 2.4 2 0 0 2 2 2 0 K1 glycoprotein Glyco_hydro_43 PF04616.14 KEY71657.1 - 1.4e-51 175.6 5.3 1.7e-51 175.2 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KEY71657.1 - 0.012 15.2 0.6 0.012 15.2 0.6 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain PAF-AH_p_II PF03403.13 KEY71658.1 - 1.6e-12 46.7 0.0 1.1e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KEY71658.1 - 7.3e-07 28.4 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KEY71658.1 - 0.00066 18.8 0.1 0.0062 15.6 0.0 2.2 2 1 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 KEY71658.1 - 0.0014 19.3 0.1 0.0027 18.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY71658.1 - 0.0023 17.2 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KEY71658.1 - 0.0044 16.8 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY71658.1 - 0.02 14.5 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KEY71660.1 - 0.00058 19.0 0.9 0.0017 17.4 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KEY71661.1 - 5.8e-27 94.8 0.0 4.3e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KEY71661.1 - 2e-05 24.0 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY71661.1 - 4.1e-05 23.0 0.1 0.0078 15.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY71661.1 - 0.00013 22.1 0.1 0.00031 20.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY71661.1 - 0.00052 19.7 0.9 0.0021 17.7 0.8 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEY71661.1 - 0.00063 18.7 0.0 0.023 13.5 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KEY71661.1 - 0.00081 18.2 0.0 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 KEY71661.1 - 0.002 17.2 0.0 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KEY71661.1 - 0.0065 17.0 0.1 7.8 7.1 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY71661.1 - 0.017 14.2 0.1 1.3 8.0 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KEY71661.1 - 0.017 14.4 0.2 0.043 13.1 0.1 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KEY71661.1 - 0.081 12.0 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Melibiase_2 PF16499.5 KEY71662.1 - 2.4e-53 181.1 4.6 1.5e-37 129.3 1.3 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KEY71662.1 - 5.2e-12 45.7 1.0 1.6e-09 37.7 0.0 3.2 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KEY71662.1 - 0.0031 16.5 0.1 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 Melibiase Fungal_trans PF04082.18 KEY71663.1 - 1.5e-05 24.1 0.2 4.7e-05 22.5 0.0 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEY71664.1 - 4e-80 269.9 17.4 4.5e-80 269.7 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71664.1 - 6.7e-20 71.3 11.6 6.7e-20 71.3 11.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 KEY71667.1 - 6.9e-74 241.9 23.9 3.9e-13 49.7 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71667.1 - 7.5e-25 87.1 0.2 0.0015 18.8 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KEY71667.1 - 7.2e-18 64.3 0.2 2.7e-05 22.9 0.0 4.0 1 1 3 4 4 4 4 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KEY71667.1 - 2.1e-15 56.5 4.0 0.23 10.4 0.0 6.1 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEY71667.1 - 5.1e-12 45.2 0.6 0.022 13.4 0.0 5.8 1 1 5 6 6 6 5 Nucleoporin Nup120/160 PD40 PF07676.12 KEY71667.1 - 2e-08 33.9 0.1 13 5.9 0.0 6.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Robl_LC7 PF03259.17 KEY71667.1 - 1e-07 31.6 0.6 17 5.3 0.0 6.0 6 0 0 6 6 6 0 Roadblock/LC7 domain PUA_3 PF17785.1 KEY71667.1 - 8e-06 25.6 1.3 1.5 8.7 0.0 5.1 6 0 0 6 6 6 2 PUA-like domain SecA_PP_bind PF01043.20 KEY71667.1 - 0.00041 21.0 0.0 8.1 7.1 0.0 4.9 2 2 4 6 6 6 1 SecA preprotein cross-linking domain VID27 PF08553.10 KEY71667.1 - 0.00059 19.0 0.1 2.1 7.3 0.0 3.1 1 1 2 4 4 4 2 VID27 C-terminal WD40-like domain Me-amine-dh_H PF06433.11 KEY71667.1 - 0.0046 15.9 0.0 9.5 5.0 0.0 3.4 1 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) nos_propeller PF18764.1 KEY71667.1 - 0.0051 16.7 0.4 1.1e+02 2.8 0.0 4.9 5 0 0 5 5 5 0 Nitrous oxide reductase propeller repeat WD40_like PF17005.5 KEY71667.1 - 0.0088 15.4 0.2 8.9 5.5 0.0 3.4 3 1 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 KEY71667.1 - 0.024 13.6 6.7 1.5 7.7 0.0 4.3 1 1 5 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KEY71667.1 - 0.059 12.4 0.0 0.32 10.0 0.0 2.1 1 1 1 2 2 2 0 Coatomer WD associated region Proteasome_A_N PF10584.9 KEY71667.1 - 0.11 12.2 8.0 1.5e+02 2.2 0.0 6.7 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature WD40_3 PF15911.5 KEY71667.1 - 0.14 12.2 0.0 33 4.6 0.0 3.6 4 1 0 4 4 4 0 WD domain, G-beta repeat DUF1283 PF06932.11 KEY71667.1 - 0.71 10.1 3.2 34 4.7 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF1283) NACHT_N PF17100.5 KEY71668.1 - 8.9e-80 267.7 2.5 8.9e-80 267.7 2.5 1.8 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KEY71668.1 - 2.5e-21 76.3 0.1 1e-20 74.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEY71668.1 - 0.00032 21.1 0.0 0.0012 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KEY71668.1 - 0.0043 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY71668.1 - 0.0078 16.5 0.1 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Phage_HK97_TLTM PF06120.11 KEY71668.1 - 0.0082 15.4 4.5 1 8.4 0.0 2.3 1 1 1 2 2 2 2 Tail length tape measure protein AAA_11 PF13086.6 KEY71668.1 - 0.011 15.5 2.4 0.67 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KEY71668.1 - 0.13 12.7 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase FemAB PF02388.16 KEY71668.1 - 0.33 9.8 2.5 0.54 9.1 2.5 1.3 1 0 0 1 1 1 0 FemAB family NPFF PF15085.6 KEY71669.1 - 0.079 13.3 2.2 0.23 11.8 1.3 1.9 1 1 1 2 2 2 0 Neuropeptide FF DUF2956 PF11169.8 KEY71669.1 - 3.9 7.7 6.4 4.9 7.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Sec34 PF04136.15 KEY71670.1 - 0.025 14.5 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Sec34-like family F-box-like PF12937.7 KEY71671.1 - 1.8e-05 24.5 0.9 1.8e-05 24.5 0.9 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KEY71671.1 - 0.001 19.0 0.1 0.0028 17.6 0.1 1.7 1 1 0 1 1 1 1 F-box-like domain Pyr_redox_2 PF07992.14 KEY71672.1 - 4.6e-48 164.0 0.7 6.4e-48 163.5 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KEY71672.1 - 3.2e-15 55.8 0.0 7.7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KEY71672.1 - 2.2e-13 50.6 2.0 3.6e-12 46.7 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KEY71672.1 - 3.9e-06 27.3 0.0 8.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KEY71672.1 - 8.1e-05 22.5 0.0 0.00032 20.6 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KEY71672.1 - 0.00041 19.6 0.0 0.1 11.7 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY71672.1 - 0.0079 16.2 0.1 9.7 6.2 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 KEY71672.1 - 0.039 13.5 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Zn_clus PF00172.18 KEY71673.1 - 0.00074 19.6 4.3 0.0015 18.6 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY71673.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tropomyosin PF00261.20 KEY71674.1 - 0.0067 15.8 4.0 0.0067 15.8 4.0 3.4 1 1 2 3 3 3 1 Tropomyosin DivIVA PF05103.13 KEY71674.1 - 0.057 13.5 18.2 4.4 7.4 0.0 3.5 2 1 0 2 2 2 0 DivIVA protein LPP PF04728.13 KEY71674.1 - 0.7 10.3 5.1 4 7.9 1.6 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper HAP1_N PF04849.13 KEY71674.1 - 1.2 8.3 30.2 0.13 11.4 1.3 3.6 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 KEY71674.1 - 3.3 7.9 14.4 0.71 10.0 1.9 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 KEY71674.1 - 3.8 6.3 10.2 5.5 5.8 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein COG5 PF10392.9 KEY71674.1 - 6.2 7.0 11.3 1.8 8.7 5.4 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF812 PF05667.11 KEY71674.1 - 6.5 5.5 23.4 14 4.4 23.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KEY71674.1 - 9.1 6.7 25.0 31 5.0 25.0 2.0 1 1 0 1 1 1 0 Fez1 adh_short PF00106.25 KEY71675.1 - 1.2e-24 86.8 0.2 2.6e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71675.1 - 1.1e-14 54.5 0.1 2e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71675.1 - 7.8e-10 38.9 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KEY71675.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3073 PF11273.8 KEY71675.1 - 0.082 13.7 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) tRNA-synt_2 PF00152.20 KEY71676.1 - 1.7e-83 280.3 0.0 2.2e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Oxidored_FMN PF00724.20 KEY71677.1 - 2.1e-35 122.6 0.0 2.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KEY71678.1 - 5.1e-18 65.1 0.0 1.1e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71678.1 - 1.2e-07 31.7 9.2 2.3e-07 30.8 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KEY71679.1 - 4.8e-17 61.8 19.2 4.8e-17 61.8 19.2 2.5 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein p450 PF00067.22 KEY71681.1 - 7.1e-61 206.3 0.0 9.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 U79_P34 PF03064.16 KEY71682.1 - 6.3 6.1 7.4 14 4.9 7.4 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pro_CA PF00484.19 KEY71683.1 - 2e-11 44.4 0.6 4.2e-10 40.1 0.6 2.1 1 1 0 1 1 1 1 Carbonic anhydrase Fungal_trans PF04082.18 KEY71685.1 - 6.3e-25 87.7 0.0 8.9e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71685.1 - 2.7e-08 33.8 11.9 6.7e-08 32.5 11.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 KEY71686.1 - 9.9e-32 110.5 0.0 1.8e-30 106.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY71686.1 - 3.7e-06 25.9 0.5 0.067 11.9 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KEY71686.1 - 4.8e-06 26.2 0.5 1.9e-05 24.2 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY71686.1 - 6.2e-06 25.6 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY71686.1 - 6e-05 22.8 1.0 6e-05 22.8 1.0 2.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY71686.1 - 0.0089 15.3 0.0 0.02 14.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEY71686.1 - 0.023 14.9 0.1 0.068 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEY71686.1 - 0.083 12.0 0.4 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KEY71686.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 KEY71687.1 - 1.3e-25 90.1 48.4 1.5e-14 53.7 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_tail_X PF05489.12 KEY71687.1 - 0.011 15.4 2.3 0.041 13.6 0.7 2.4 2 0 0 2 2 2 0 Phage Tail Protein X Condensation PF00668.20 KEY71688.1 - 0.034 12.8 0.1 0.78 8.3 0.0 2.2 2 0 0 2 2 2 0 Condensation domain ELF PF03317.13 KEY71688.1 - 0.18 11.8 0.0 0.96 9.5 0.0 2.1 2 0 0 2 2 2 0 ELF protein Beta-lactamase PF00144.24 KEY71689.1 - 2.1e-29 102.8 0.4 3.1e-29 102.3 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.25 KEY71690.1 - 2.3e-25 89.2 0.1 2.7e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71690.1 - 1.4e-14 54.3 0.1 3.2e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71690.1 - 1.3e-08 35.0 0.1 1.9e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY71690.1 - 0.00032 20.3 0.0 0.00058 19.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY71690.1 - 0.0082 15.6 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF3425 PF11905.8 KEY71691.1 - 1.9e-15 56.9 0.0 4.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Methyltransf_25 PF13649.6 KEY71692.1 - 1.8e-12 47.8 0.0 2.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71692.1 - 5.4e-11 43.0 0.0 8.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71692.1 - 4.3e-09 37.0 0.0 6.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71692.1 - 9.7e-08 31.9 0.0 1.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71692.1 - 2.1e-07 30.5 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEY71692.1 - 1.6e-06 28.1 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY71692.1 - 6.1e-05 22.6 0.0 9.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KEY71692.1 - 0.00019 21.1 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KEY71692.1 - 0.0012 18.2 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KEY71692.1 - 0.002 17.4 0.0 0.0061 15.8 0.0 1.7 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family CMAS PF02353.20 KEY71692.1 - 0.0058 16.0 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 KEY71692.1 - 0.017 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Rsm22 PF09243.10 KEY71692.1 - 0.036 13.4 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Acetyltransf_1 PF00583.25 KEY71693.1 - 1.1e-07 32.0 0.1 1.4e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY71693.1 - 1.7e-05 24.8 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY71693.1 - 2.1e-05 24.8 0.1 3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 KEY71696.1 - 3.8e-19 68.8 2.2 8e-19 67.8 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain CBM_35 PF16990.5 KEY71696.1 - 0.093 13.0 1.8 9.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) BBE PF08031.12 KEY71696.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like AAA PF00004.29 KEY71697.1 - 1.7e-17 64.1 0.0 3.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY71697.1 - 0.00024 21.4 0.1 0.0052 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KEY71697.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEY71697.1 - 0.021 15.2 0.1 0.057 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KEY71697.1 - 0.024 14.4 0.0 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KEY71697.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KEY71697.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEY71697.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEY71697.1 - 0.16 12.5 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Trp_DMAT PF11991.8 KEY71700.1 - 2.6e-82 277.1 0.0 3.3e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF3471 PF11954.8 KEY71700.1 - 0.038 14.5 0.1 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) DUF5324 PF17258.2 KEY71700.1 - 0.17 11.5 0.2 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5324) Glyco_hydro_61 PF03443.14 KEY71701.1 - 6.5e-53 179.7 0.0 7.5e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N_2 PF16884.5 KEY71701.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 KEY71702.1 - 2.6e-14 52.9 0.2 4.6e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71702.1 - 7.1e-05 22.8 7.9 7.1e-05 22.8 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 KEY71703.1 - 1e-32 113.5 0.1 1.4e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY71703.1 - 5.5e-06 26.3 0.2 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEY71703.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 SpecificRecomb PF10136.9 KEY71703.1 - 0.12 10.7 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Site-specific recombinase DUF1989 PF09347.10 KEY71704.1 - 5.4e-53 179.0 0.1 1.4e-52 177.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 KEY71704.1 - 1.8e-17 63.4 0.0 3.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KEY71704.1 - 4.7e-06 26.4 0.0 1e-05 25.3 0.0 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) FAD_binding_3 PF01494.19 KEY71705.1 - 1.7e-66 224.8 0.0 2.1e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY71705.1 - 2.9e-05 23.8 0.0 6.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 KEY71705.1 - 4e-05 23.7 0.1 0.00033 20.7 0.0 2.2 1 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.14 KEY71705.1 - 4.2e-05 22.6 0.0 9.2e-05 21.5 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KEY71705.1 - 8.3e-05 22.0 0.3 0.0019 17.5 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY71705.1 - 0.00086 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY71705.1 - 0.0017 17.5 0.0 0.005 16.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY71705.1 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEY71705.1 - 0.005 17.0 0.0 0.018 15.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY71705.1 - 0.0056 15.8 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KEY71705.1 - 0.0066 17.0 0.1 0.016 15.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY71705.1 - 0.024 13.4 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KEY71705.1 - 0.046 13.1 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KEY71705.1 - 0.15 11.5 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KEY71706.1 - 7.3e-37 127.1 28.4 7.3e-37 127.1 28.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 KEY71707.1 - 1.9e-13 51.3 0.0 2.2e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY71707.1 - 0.026 14.8 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 KEY71707.1 - 0.092 12.3 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase YfhD PF14151.6 KEY71709.1 - 0.0023 18.0 0.1 0.0046 17.1 0.1 1.4 1 0 0 1 1 1 1 YfhD-like protein OmdA PF13376.6 KEY71710.1 - 2.5e-22 78.7 0.0 5.8e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Glyco_hydro_76 PF03663.14 KEY71712.1 - 3.5e-145 484.2 6.0 4e-145 483.9 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY71712.1 - 0.0001 21.5 3.1 0.44 9.6 0.0 3.0 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 adh_short PF00106.25 KEY71713.1 - 9.2e-40 136.2 0.0 2.4e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71713.1 - 6.4e-21 75.0 0.0 1.6e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 KEY71713.1 - 6.1e-16 58.8 0.0 1.4e-09 38.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PNP_UDP_1 PF01048.20 KEY71713.1 - 6.2e-15 55.1 0.1 1.2e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_4 PF13637.6 KEY71713.1 - 3.3e-12 46.7 0.0 9.5e-06 26.1 0.0 4.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY71713.1 - 1.3e-10 41.2 0.0 4.4e-05 23.7 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KEY71713.1 - 1.1e-09 37.7 0.0 7.9e-05 22.8 0.0 4.3 4 0 0 4 4 3 2 Ankyrin repeat NACHT PF05729.12 KEY71713.1 - 1.8e-08 34.5 0.1 5.5e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY71713.1 - 4.3e-06 27.2 0.2 1.2e-05 25.8 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain KR PF08659.10 KEY71713.1 - 9.6e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Ank_5 PF13857.6 KEY71713.1 - 4.1e-05 23.8 0.2 0.028 14.8 0.2 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) AAA PF00004.29 KEY71713.1 - 5.3e-05 23.6 0.0 0.00027 21.4 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY71713.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain F420_oxidored PF03807.17 KEY71713.1 - 0.00077 20.0 0.4 0.0026 18.3 0.4 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KEY71713.1 - 0.0039 16.7 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAP_NTPase PF07693.14 KEY71713.1 - 0.005 16.1 2.8 0.012 14.9 1.9 1.8 1 1 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 KEY71713.1 - 0.02 14.6 0.1 0.065 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KEY71713.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Shikimate_DH PF01488.20 KEY71713.1 - 0.094 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KEY71713.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEY71713.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KEY71713.1 - 0.11 12.3 0.5 0.26 11.2 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_19 PF13245.6 KEY71713.1 - 0.12 12.7 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KEY71713.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KEY71713.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain OPT PF03169.15 KEY71714.1 - 4.6e-12 45.4 0.3 6.3e-12 44.9 0.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidase PF01425.21 KEY71715.1 - 1.9e-15 56.8 0.1 2.4e-11 43.3 0.0 2.0 2 0 0 2 2 2 2 Amidase Salp15 PF12115.8 KEY71716.1 - 0.012 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation EphA2_TM PF14575.6 KEY71717.1 - 0.0016 19.3 0.0 0.0023 18.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 KEY71717.1 - 0.002 18.6 0.9 0.0029 18.0 0.9 1.2 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Herpes_gE PF02480.16 KEY71717.1 - 0.013 14.3 1.2 0.015 14.1 1.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF456 PF04306.13 KEY71717.1 - 0.031 14.6 0.5 0.039 14.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) CopD PF05425.13 KEY71717.1 - 0.081 13.3 1.1 0.14 12.6 1.1 1.4 1 0 0 1 1 1 0 Copper resistance protein D SKG6 PF08693.10 KEY71717.1 - 0.15 11.5 5.8 0.27 10.7 5.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KEY71717.1 - 0.21 11.4 10.8 0.36 10.6 10.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAG1 PF05454.11 KEY71717.1 - 0.22 10.9 0.1 0.25 10.7 0.1 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Syndecan PF01034.20 KEY71717.1 - 0.23 11.4 1.2 0.34 10.9 1.2 1.2 1 0 0 1 1 1 0 Syndecan domain Hum_adeno_E3A PF05393.11 KEY71717.1 - 0.28 11.2 2.0 0.39 10.7 2.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4448 PF14610.6 KEY71717.1 - 0.29 10.9 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LapA_dom PF06305.11 KEY71717.1 - 0.77 9.6 1.9 0.73 9.7 0.2 1.7 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain RCR PF12273.8 KEY71717.1 - 5.1 7.8 7.2 0.27 11.9 1.7 1.8 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Hexapep PF00132.24 KEY71718.1 - 5.6e-14 51.2 7.7 2.6e-11 42.8 6.3 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KEY71718.1 - 5.7e-14 52.1 0.0 9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KEY71718.1 - 7.9e-13 47.9 6.4 2.6e-10 39.9 5.9 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase PAF-AH_p_II PF03403.13 KEY71719.1 - 3.2e-06 25.9 0.0 0.0009 17.9 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KEY71719.1 - 0.0009 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KEY71719.1 - 0.0027 17.0 0.1 0.26 10.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY71719.1 - 0.047 13.3 0.0 0.092 12.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY71719.1 - 0.066 12.7 0.1 0.21 11.1 0.1 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY71719.1 - 6.1 7.4 19.5 0.21 12.2 11.5 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.22 KEY71720.1 - 7.9e-57 193.0 0.0 1e-56 192.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY71722.1 - 2.4e-26 92.1 1.4 4.7e-26 91.2 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY71722.1 - 2.7e-08 33.8 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.21 KEY71723.1 - 4.2e-65 219.8 0.0 4.8e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 KEY71724.1 - 7.5e-76 255.4 0.1 1.3e-75 254.6 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_1 PF00175.21 KEY71724.1 - 0.035 14.7 0.0 0.086 13.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain EMP70 PF02990.16 KEY71724.1 - 0.13 10.9 0.7 0.2 10.3 0.7 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 ECH_1 PF00378.20 KEY71725.1 - 6.8e-67 225.4 0.0 7.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY71725.1 - 5.4e-34 118.2 0.1 2.8e-29 102.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase NACHT PF05729.12 KEY71726.1 - 1.3e-08 34.9 0.0 3.5e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY71726.1 - 0.009 16.4 0.0 0.07 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KEY71726.1 - 0.02 15.5 0.1 0.11 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain Helo_like_N PF17111.5 KEY71726.1 - 0.026 13.9 2.1 0.045 13.1 2.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RNA_helicase PF00910.22 KEY71726.1 - 0.027 14.9 0.0 0.081 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SesA PF17107.5 KEY71726.1 - 0.051 13.8 0.5 0.12 12.6 0.5 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases KAP_NTPase PF07693.14 KEY71726.1 - 0.1 11.8 0.8 7.7 5.6 0.2 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 KEY71726.1 - 0.17 12.3 0.0 0.76 10.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hydantoinase_B PF02538.14 KEY71726.1 - 0.18 10.2 0.2 0.32 9.3 0.2 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase ABC_tran PF00005.27 KEY71726.1 - 0.25 11.8 0.4 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Cupin_2 PF07883.11 KEY71727.1 - 8.7e-15 54.2 0.1 1.4e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEY71727.1 - 2.1e-07 30.6 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KEY71727.1 - 1.7e-06 27.7 0.1 2.3e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 KEY71727.1 - 5.9e-05 22.8 0.1 6.8e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 KEY71727.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 KEY71727.1 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 KEY71727.1 - 0.0089 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_7 PF12973.7 KEY71727.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Cupin_4 PF08007.12 KEY71727.1 - 0.067 12.6 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein CENP-C_C PF11699.8 KEY71727.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Pirin PF02678.16 KEY71727.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Pirin cNMP_binding PF00027.29 KEY71727.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Arrestin_N PF00339.29 KEY71728.1 - 0.00032 20.8 0.0 0.0028 17.7 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Amidase PF01425.21 KEY71729.1 - 6.1e-83 279.3 0.0 2.7e-60 204.6 0.0 2.2 1 1 1 2 2 2 2 Amidase HET PF06985.11 KEY71729.1 - 3.1e-24 86.0 0.0 7.2e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.14 KEY71729.1 - 0.062 13.7 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme BPL_N PF09825.9 KEY71729.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AAA PF00004.29 KEY71730.1 - 3.6e-17 63.0 0.0 6.7e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY71730.1 - 0.001 19.3 0.7 0.0083 16.4 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY71730.1 - 0.0034 17.8 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEY71730.1 - 0.0039 17.2 0.1 0.0096 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEY71730.1 - 0.027 14.2 0.2 0.079 12.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEY71730.1 - 0.057 13.8 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KEY71730.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PNP_UDP_1 PF01048.20 KEY71731.1 - 9.8e-15 54.4 0.3 8.4e-14 51.4 0.3 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily HET PF06985.11 KEY71734.1 - 3.7e-21 76.0 0.1 1.2e-20 74.3 0.1 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 KEY71735.1 - 1e-13 51.2 10.9 1.8e-13 50.3 10.9 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KEY71735.1 - 0.017 15.4 1.9 0.04 14.2 1.9 1.5 1 0 0 1 1 1 0 Gamma-thionin family UPF0149 PF03695.13 KEY71735.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) DUF347 PF03988.12 KEY71735.1 - 2.4 8.4 7.4 0.38 11.0 1.0 2.8 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Zn_clus PF00172.18 KEY71736.1 - 8.1e-10 38.7 10.0 1.9e-09 37.5 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KEY71737.1 - 2.4e-22 79.9 0.0 5.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.30 KEY71738.1 - 5.3e-21 74.1 4.4 2.8e-07 30.7 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KEY71738.1 - 1e-17 64.5 0.1 6.5e-13 49.1 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY71738.1 - 3.3e-16 59.1 4.2 1.6e-11 44.2 0.4 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY71738.1 - 2.2e-14 52.1 0.2 3.5e-06 26.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KEY71738.1 - 3.2e-13 49.9 4.8 5.4e-08 33.2 1.9 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) WXG100 PF06013.12 KEY71738.1 - 0.0069 16.6 0.5 0.043 14.0 0.0 2.5 3 0 0 3 3 3 1 Proteins of 100 residues with WXG zf-C2H2_2 PF12756.7 KEY71740.1 - 8.3e-24 83.8 3.1 2.6e-22 79.1 2.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEY71740.1 - 0.024 15.4 4.0 5.7 8.1 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KEY71740.1 - 0.069 13.6 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type HicA_toxin PF07927.12 KEY71742.1 - 0.00028 20.9 0.0 0.0031 17.5 0.0 2.9 3 0 0 3 3 3 1 HicA toxin of bacterial toxin-antitoxin, TFIIE-A_C PF11521.8 KEY71742.1 - 0.55 10.6 6.9 1.7 9.0 6.9 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Dynamin_N PF00350.23 KEY71743.1 - 3e-33 115.3 0.3 5.5e-32 111.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEY71743.1 - 1e-18 67.6 0.0 3.5e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Nucleoporin_FG PF13634.6 KEY71743.1 - 2.2e-08 34.8 40.6 2.4e-05 25.1 16.2 3.5 2 1 2 4 4 4 3 Nucleoporin FG repeat region MMR_HSR1 PF01926.23 KEY71743.1 - 1.7e-05 24.8 0.0 7.2e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KEY71743.1 - 0.0004 20.5 0.6 0.0011 19.1 0.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Roc PF08477.13 KEY71743.1 - 0.00049 20.3 0.0 0.65 10.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KEY71743.1 - 0.018 14.7 0.4 0.071 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KEY71743.1 - 0.068 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEY71743.1 - 0.14 12.5 0.5 1 9.8 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KEY71743.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.13 KEY71744.1 - 1.2e-26 93.9 0.7 5.8e-26 91.7 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEY71744.1 - 4.8e-06 25.7 0.0 6.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KEY71744.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY71744.1 - 0.19 11.2 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family MmgE_PrpD PF03972.14 KEY71745.1 - 1.6e-63 214.8 0.2 1.8e-63 214.6 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family UBA_6 PF18039.1 KEY71745.1 - 0.68 9.9 2.9 99 3.0 0.0 3.9 4 0 0 4 4 4 0 UBA-like domain adh_short PF00106.25 KEY71746.1 - 6.8e-37 126.8 0.0 9.3e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71746.1 - 1.5e-24 86.8 0.0 2.3e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71746.1 - 8e-12 45.4 0.0 1.5e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY71746.1 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Ank PF00023.30 KEY71747.1 - 3.6e-13 49.3 0.1 4.6e-07 30.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KEY71747.1 - 4.4e-13 49.6 0.0 2.2e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY71747.1 - 4.2e-09 35.9 0.1 0.0053 17.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KEY71747.1 - 1e-08 35.6 0.1 1.4e-06 28.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY71747.1 - 7.6e-08 32.5 0.1 2.1e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DYW_deaminase PF14432.6 KEY71747.1 - 6.3e-06 26.1 0.1 0.00018 21.4 0.1 2.4 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases Zn_Tnp_IS1595 PF12760.7 KEY71747.1 - 3.8 7.6 5.8 7.2 6.7 1.5 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Gly_transf_sug PF04488.15 KEY71748.1 - 2.4e-10 40.9 0.0 4.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KEY71748.1 - 3.5e-08 33.2 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KEY71748.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Sulfate_transp PF00916.20 KEY71749.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Sulfate permease family TMEM154 PF15102.6 KEY71749.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KEY71749.1 - 0.38 10.2 3.5 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mannosyl_trans3 PF11051.8 KEY71752.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative FAD_binding_3 PF01494.19 KEY71754.1 - 3.9e-67 227.0 0.0 8.6e-67 225.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain HD PF01966.22 KEY71755.1 - 9.9e-05 22.6 0.0 0.00021 21.5 0.0 1.5 1 1 0 1 1 1 1 HD domain Helo_like_N PF17111.5 KEY71756.1 - 0.0061 15.9 0.5 0.014 14.7 0.3 1.8 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEY71756.1 - 0.008 16.4 1.8 0.008 16.4 1.8 2.0 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Trp_repressor PF01371.19 KEY71756.1 - 0.084 13.0 0.2 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 Trp repressor protein RmuC PF02646.16 KEY71757.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 RmuC family DUF5427 PF10310.9 KEY71757.1 - 6.5 5.6 6.0 10 4.9 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5427) Abhydrolase_6 PF12697.7 KEY71758.1 - 0.00067 20.3 0.1 0.004 17.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KEY71758.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KEY71758.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 KEY71758.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.13 KEY71758.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase CHAT PF12770.7 KEY71759.1 - 9.9e-34 117.1 0.1 1.8e-33 116.2 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_19 PF14559.6 KEY71759.1 - 1.8e-06 28.4 2.5 0.07 13.7 1.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY71759.1 - 6.2e-05 23.5 4.9 0.4 11.6 0.3 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY71759.1 - 0.00031 20.6 5.7 0.08 13.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY71759.1 - 0.00069 19.9 6.6 1 9.7 0.0 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY71759.1 - 0.0056 16.9 0.4 3 8.1 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEY71759.1 - 0.0077 16.1 4.6 9.4 6.3 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY71759.1 - 0.012 15.6 1.3 12 6.2 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY71759.1 - 0.015 16.0 5.8 0.22 12.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY71759.1 - 0.019 15.1 0.7 3 8.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 KEY71759.1 - 0.032 13.4 0.1 0.069 12.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C50 TPR_11 PF13414.6 KEY71759.1 - 0.082 12.6 0.1 3.1 7.6 0.1 2.9 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 KEY71759.1 - 0.1 13.3 4.8 46 5.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat F420H2_quin_red PF04075.14 KEY71761.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase Ist1 PF03398.14 KEY71762.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway F-box-like PF12937.7 KEY71762.1 - 0.19 11.6 1.1 0.73 9.8 0.0 2.5 2 0 0 2 2 2 0 F-box-like Thr_synth_N PF14821.6 KEY71763.1 - 2.3e-28 98.2 0.0 5.4e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KEY71763.1 - 1.4e-15 57.5 0.0 1.5e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIA PF03153.13 KEY71764.1 - 0.69 9.9 10.0 0.99 9.3 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 KEY71764.1 - 1.9 7.8 15.1 2.6 7.4 15.1 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 KEY71764.1 - 2.4 7.2 10.1 3.9 6.5 10.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 KEY71764.1 - 7.6 4.6 12.5 11 4.1 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family NAT PF04768.13 KEY71765.1 - 5.1e-42 143.4 0.0 2.1e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KEY71765.1 - 3e-26 92.5 0.0 1.4e-20 73.9 0.0 2.4 2 0 0 2 2 2 2 Amino acid kinase family GFA PF04828.14 KEY71767.1 - 6.8e-11 42.4 0.5 6.8e-11 42.4 0.5 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HeLo PF14479.6 KEY71769.1 - 1.7e-38 132.5 0.1 2.8e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Glyco_trans_2_3 PF13632.6 KEY71770.1 - 1.7e-10 41.1 0.7 1.7e-10 41.1 0.7 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY71770.1 - 2.7e-09 37.2 0.1 3.5e-08 33.6 0.0 2.1 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 KEY71770.1 - 1.7e-06 27.0 0.4 2.5e-05 23.1 0.4 2.2 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.6 KEY71770.1 - 2.4e-06 27.1 0.1 1.6e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Fringe PF02434.16 KEY71771.1 - 2.7e-06 27.0 1.9 2.4e-05 23.9 1.1 2.4 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KEY71771.1 - 0.013 15.4 3.8 0.03 14.2 3.8 1.6 1 0 0 1 1 1 0 PAN domain DUF4585 PF15232.6 KEY71771.1 - 0.095 12.8 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) MFS_1 PF07690.16 KEY71772.1 - 2.2e-27 96.0 35.9 2.2e-27 96.0 35.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KEY71772.1 - 0.04 12.2 6.1 0.089 11.1 0.2 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_4 PF01565.23 KEY71773.1 - 6.5e-24 84.3 0.8 1.4e-23 83.1 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY71773.1 - 7.4e-12 45.2 0.2 1.4e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like AA_permease PF00324.21 KEY71775.1 - 4.2e-134 447.7 49.0 5e-134 447.5 49.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY71775.1 - 3e-33 115.3 59.6 1.8e-32 112.8 59.9 1.8 1 1 0 1 1 1 1 Amino acid permease PSDC PF12588.8 KEY71776.1 - 2.4e-62 209.0 0.0 3.6e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KEY71776.1 - 4.1e-36 124.4 0.0 5.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KEY71776.1 - 0.0066 16.2 0.3 0.029 14.2 0.5 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 KEY71776.1 - 0.041 14.1 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 KEY71776.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Aldo_ket_red PF00248.21 KEY71777.1 - 1.4e-70 237.9 0.1 1.5e-70 237.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnC_trans_reg2 PF17805.1 KEY71777.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AsnC-like ligand binding domain MCC-bdg_PDZ PF10506.9 KEY71777.1 - 0.53 10.3 2.3 1.3 9.1 0.8 2.1 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HET PF06985.11 KEY71781.1 - 2.8e-30 105.6 0.2 4.5e-30 104.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M19 PF01244.21 KEY71782.1 - 1e-100 337.0 0.0 1.3e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Tyrosinase PF00264.20 KEY71783.1 - 7.1e-40 137.6 0.5 9.4e-40 137.3 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.19 KEY71783.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box CBM_11 PF03425.13 KEY71785.1 - 0.0002 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Sugar_tr PF00083.24 KEY71786.1 - 2e-107 359.9 19.0 2.3e-107 359.7 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71786.1 - 2.2e-25 89.4 31.2 7.6e-24 84.3 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KEY71786.1 - 8.8e-05 21.6 0.4 8.8e-05 21.6 0.4 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Bac_rhamnosid6H PF17389.2 KEY71787.1 - 4.1e-92 309.1 0.3 5.5e-92 308.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KEY71787.1 - 7.8e-53 178.8 0.0 1.2e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KEY71787.1 - 5.8e-18 64.8 0.0 1.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KEY71787.1 - 8.6e-17 60.7 0.0 2.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KEY71787.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Fungal_trans PF04082.18 KEY71788.1 - 6e-05 22.2 0.0 8.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KEY71789.1 - 3.6e-36 124.9 0.0 8.1e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 KEY71789.1 - 4.2e-36 124.5 0.0 1.2e-17 64.7 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane PF01061.24 KEY71789.1 - 3e-33 115.0 16.8 3e-33 115.0 16.8 2.5 3 0 0 3 3 3 1 ABC-2 type transporter PDR_CDR PF06422.12 KEY71789.1 - 3.4e-26 91.0 0.5 8.3e-25 86.5 0.0 2.6 2 0 0 2 2 2 1 CDR ABC transporter AAA_16 PF13191.6 KEY71789.1 - 1.5e-07 31.9 0.4 0.016 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEY71789.1 - 8.1e-06 25.8 0.1 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KEY71789.1 - 9e-05 22.7 0.4 2.5 8.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 KEY71789.1 - 9.4e-05 22.1 2.1 0.0035 17.0 0.4 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KEY71789.1 - 0.00039 21.0 0.0 0.083 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEY71789.1 - 0.00068 19.5 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KEY71789.1 - 0.00091 18.4 7.9 0.0019 17.3 7.9 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KEY71789.1 - 0.0012 18.5 3.3 0.16 11.7 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 KEY71789.1 - 0.0015 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.6 KEY71789.1 - 0.0037 17.5 0.1 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEY71789.1 - 0.012 15.0 0.0 0.45 9.9 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEY71789.1 - 0.02 14.8 0.2 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KEY71789.1 - 0.034 13.9 0.1 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEY71789.1 - 0.039 14.0 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KEY71789.1 - 0.069 12.9 0.4 29 4.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KEY71789.1 - 0.091 12.3 2.5 0.47 10.0 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KEY71789.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEY71789.1 - 0.12 11.7 0.1 13 5.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin p450 PF00067.22 KEY71790.1 - 1.5e-33 116.3 0.0 3.9e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KEY71792.1 - 6.1e-28 97.8 0.0 3.2e-27 95.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY71793.1 - 4.2e-24 85.1 0.0 2.9e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.19 KEY71794.1 - 3.3e-18 66.0 12.8 1.6e-16 60.5 12.8 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY71794.1 - 3e-05 23.9 19.4 5.9e-05 23.0 18.0 2.2 1 1 0 1 1 1 1 Right handed beta helix region SMP PF04927.12 KEY71794.1 - 0.21 12.1 3.1 12 6.4 2.4 2.4 2 0 0 2 2 2 0 Seed maturation protein MFS_1 PF07690.16 KEY71795.1 - 3.4e-23 82.2 33.0 7.4e-23 81.0 31.0 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KEY71796.1 - 4e-74 249.7 0.0 8.9e-74 248.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KEY71796.1 - 4e-72 242.8 0.0 7.8e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KEY71796.1 - 3.4e-56 190.8 0.0 6.4e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KEY71796.1 - 1.2e-50 172.0 0.0 1.7e-48 164.9 0.0 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEY71796.1 - 2.2e-44 152.2 0.0 5.6e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY71796.1 - 1.7e-43 148.9 0.1 2.9e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY71796.1 - 4.9e-31 107.2 0.1 1.1e-30 106.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KEY71796.1 - 2.7e-28 98.8 0.0 1.9e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KEY71796.1 - 3.7e-19 69.3 0.0 1.7e-18 67.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY71796.1 - 2.3e-16 60.2 0.0 1.4e-14 54.5 0.0 3.1 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY71796.1 - 6.5e-16 58.4 1.2 1.7e-07 31.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KEY71796.1 - 2.3e-14 53.5 0.0 5.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71796.1 - 1.1e-13 51.6 0.0 3.6e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71796.1 - 1.3e-13 51.4 0.0 5.9e-13 49.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71796.1 - 4.7e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEY71796.1 - 1.1e-09 38.2 0.0 9.7e-08 31.8 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEY71796.1 - 2.5e-09 36.9 0.0 3.9e-08 33.0 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KEY71796.1 - 8.6e-06 25.0 0.0 0.00082 18.5 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KEY71796.1 - 9e-06 25.2 0.1 1.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KEY71796.1 - 3.4e-05 23.7 0.5 0.00016 21.5 0.5 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KEY71796.1 - 0.00034 20.0 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 KEY71796.1 - 0.0027 18.6 0.0 0.019 15.9 0.0 2.6 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 KEY71796.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase NodS PF05401.11 KEY71796.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KEY71796.1 - 0.23 11.3 0.0 0.62 9.9 0.0 1.6 2 0 0 2 2 1 0 Hypothetical methyltransferase FAM70 PF14967.6 KEY71797.1 - 0.14 11.6 0.9 0.26 10.7 0.9 1.4 1 0 0 1 1 1 0 FAM70 protein p450 PF00067.22 KEY71798.1 - 4.5e-46 157.6 0.0 5.8e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KEY71799.1 - 2.5e-09 37.2 0.0 6.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY71799.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF2264 PF10022.9 KEY71800.1 - 3.6e-95 319.1 0.0 4.5e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) V-SNARE_C PF12352.8 KEY71801.1 - 1.5e-13 50.8 1.1 9.4e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KEY71801.1 - 2e-05 24.4 0.1 0.00015 21.6 0.0 2.1 2 1 0 2 2 2 1 Sec20 TPR_MLP1_2 PF07926.12 KEY71801.1 - 0.017 15.2 2.1 0.017 15.2 2.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GP3_package PF16677.5 KEY71801.1 - 0.041 14.0 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 DNA-packaging protein gp3 Nup54_57_C PF18570.1 KEY71801.1 - 0.19 11.4 1.5 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Snf7 PF03357.21 KEY71801.1 - 0.22 11.1 2.0 0.26 10.8 0.4 1.8 2 0 0 2 2 2 0 Snf7 DivIC PF04977.15 KEY71801.1 - 0.67 9.8 6.7 15 5.4 0.1 3.3 2 2 1 3 3 3 0 Septum formation initiator PspB PF06667.12 KEY71801.1 - 1.3 9.1 5.2 3.7 7.7 5.2 1.8 1 0 0 1 1 1 0 Phage shock protein B TPK_catalytic PF04263.16 KEY71802.1 - 8.9e-30 103.2 0.0 1.5e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KEY71802.1 - 2.3e-22 78.5 0.1 3.3e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 KEY71803.1 - 9.5e-05 22.4 5.3 0.00015 21.8 5.3 1.4 1 0 0 1 1 1 1 CHCH domain DUF5353 PF17304.2 KEY71804.1 - 2.1e-11 43.4 4.9 3.2e-11 42.8 4.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) NPH3 PF03000.14 KEY71804.1 - 0.03 14.0 0.4 0.04 13.6 0.4 1.1 1 0 0 1 1 1 0 NPH3 family PAP1 PF08601.10 KEY71804.1 - 0.049 13.4 2.1 0.063 13.0 2.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Myb_DNA-bind_3 PF12776.7 KEY71805.1 - 3.9e-24 85.5 0.6 3.9e-24 85.5 0.6 1.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NmrA PF05368.13 KEY71806.1 - 2.6e-14 53.4 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY71806.1 - 2.2e-11 44.0 0.2 4.3e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY71806.1 - 0.0042 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KEY71806.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KEY71806.1 - 0.02 15.3 0.1 0.039 14.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEY71806.1 - 0.071 13.7 0.5 0.18 12.4 0.5 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Histone PF00125.24 KEY71808.1 - 7.9e-18 65.1 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KEY71808.1 - 7.5e-13 48.0 0.1 1.9e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KEY71808.1 - 6.6e-05 23.1 0.0 9.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMC_oxred_N PF00732.19 KEY71809.1 - 2.8e-53 181.2 0.0 4.8e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY71809.1 - 8.7e-32 110.6 0.0 1.6e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY71809.1 - 0.19 12.0 0.3 0.72 10.1 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KEY71810.1 - 3.9e-45 152.3 0.7 4.9e-12 46.3 0.0 9.0 9 2 3 12 12 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY71810.1 - 2.5e-26 91.7 4.6 0.00069 20.1 0.0 10.9 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 KEY71810.1 - 1.6e-24 85.2 10.2 0.0003 21.1 0.9 11.7 11 0 0 11 11 11 4 Ankyrin repeat Ank_3 PF13606.6 KEY71810.1 - 4.1e-20 69.7 0.7 0.0014 18.9 0.1 12.4 14 0 0 14 14 12 2 Ankyrin repeat Ank_5 PF13857.6 KEY71810.1 - 1.1e-15 57.4 2.7 0.00038 20.7 0.0 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) NACHT PF05729.12 KEY71810.1 - 2.1e-12 47.3 0.0 4.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 KEY71810.1 - 3e-05 23.5 0.0 0.00032 20.1 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA PF00004.29 KEY71810.1 - 6e-05 23.5 0.0 0.00018 21.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PNP_UDP_1 PF01048.20 KEY71810.1 - 0.00024 20.5 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily ATPase_2 PF01637.18 KEY71810.1 - 0.0018 18.3 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KEY71810.1 - 0.0079 16.5 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY71810.1 - 0.016 15.6 0.0 0.051 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KEY71810.1 - 0.032 14.3 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_12 PF01670.16 KEY71811.1 - 1.8e-20 73.9 1.1 1.2e-18 67.9 1.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_trans_2_3 PF13632.6 KEY71812.1 - 1.5e-16 60.9 0.4 1.5e-16 60.9 0.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY71812.1 - 1.8e-16 60.7 0.0 2.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEY71812.1 - 3e-12 46.7 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KEY71812.1 - 2.3e-11 42.9 4.5 2.7e-07 29.5 1.9 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 KEY71812.1 - 5.2e-11 42.3 0.0 9.1e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 HATPase_c PF02518.26 KEY71813.1 - 1e-22 80.8 0.0 2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY71813.1 - 1.9e-17 63.5 0.5 4e-17 62.4 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 KEY71813.1 - 2.3e-09 37.5 0.0 1.1e-05 25.7 0.0 3.3 2 1 0 2 2 2 2 PAS fold HisKA PF00512.25 KEY71813.1 - 3.7e-08 33.3 0.2 1e-07 31.9 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KEY71813.1 - 1.7e-07 31.2 0.0 4.7e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEY71813.1 - 1.9e-06 28.1 0.0 6.9e-05 23.0 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KEY71813.1 - 3.9e-05 23.6 0.0 0.00014 21.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KEY71813.1 - 0.00012 22.3 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold Tocopherol_cycl PF14249.6 KEY71814.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Tocopherol cyclase Sugar_tr PF00083.24 KEY71815.1 - 5.6e-99 332.0 22.4 6.8e-99 331.8 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71815.1 - 1e-19 70.7 21.5 1e-19 70.7 21.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY71815.1 - 4.5e-05 22.1 1.8 4.5e-05 22.1 1.8 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KEY71815.1 - 0.44 11.1 3.1 0.65 10.6 1.0 2.5 2 1 0 2 2 2 0 Phage holin family 2 ABC2_membrane_2 PF12679.7 KEY71815.1 - 3.7 6.7 9.2 2.3 7.4 6.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein FAD_binding_4 PF01565.23 KEY71816.1 - 1.5e-22 79.8 1.0 3.3e-22 78.7 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY71816.1 - 0.014 15.5 0.7 0.16 12.1 0.1 2.3 2 0 0 2 2 2 0 Berberine and berberine like Arylsulfotran_2 PF14269.6 KEY71818.1 - 3.1e-57 194.3 3.1 4.2e-57 193.8 3.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEY71818.1 - 2.7e-21 75.9 3.2 5.1e-21 75.0 3.2 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DNA_ligase_C PF17879.1 KEY71818.1 - 0.11 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 DNA ligase C-terminal domain Asp_protease_2 PF13650.6 KEY71820.1 - 0.00022 21.8 0.0 0.00069 20.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KEY71820.1 - 0.00059 20.3 0.0 0.0017 18.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Zn_clus PF00172.18 KEY71821.1 - 0.005 16.9 1.4 0.0093 16.1 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KEY71823.1 - 9.4e-47 158.9 3.6 7.4e-46 155.9 1.5 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEY71823.1 - 5.3e-23 82.4 1.6 9.5e-23 81.6 1.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEY71823.1 - 1.1e-07 32.1 0.3 1.1e-06 28.9 0.1 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.7 KEY71823.1 - 0.15 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KEY71824.1 - 1e-118 397.1 23.1 1.2e-118 396.9 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY71824.1 - 1.5e-21 76.7 62.1 5.9e-19 68.2 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 KEY71825.1 - 2.1e-06 27.5 3.5 3.8e-06 26.7 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain PaRep2a PF07903.11 KEY71825.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 PaRep2a protein Glyco_transf_8 PF01501.20 KEY71826.1 - 0.021 14.4 0.0 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 zf-RING_2 PF13639.6 KEY71827.1 - 1.7e-05 25.1 12.2 3.9e-05 23.9 12.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEY71827.1 - 0.0034 17.2 10.9 0.0075 16.1 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY71827.1 - 0.005 16.7 8.7 0.011 15.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY71827.1 - 0.06 13.4 3.9 0.19 11.8 3.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 KEY71827.1 - 0.11 12.5 7.8 0.23 11.4 7.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KEY71827.1 - 0.15 12.2 7.1 0.32 11.2 7.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KEY71827.1 - 0.25 11.5 9.0 0.58 10.4 9.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KEY71827.1 - 0.27 10.9 8.5 0.5 10.0 8.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KEY71827.1 - 0.49 10.7 9.5 1.3 9.4 9.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KEY71827.1 - 1.1 9.2 11.5 2.5 8.0 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_1 PF00583.25 KEY71830.1 - 0.00026 21.2 0.0 0.00075 19.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY71830.1 - 0.00055 20.3 0.0 0.0015 19.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY71830.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KEY71830.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase ANAPC4_WD40 PF12894.7 KEY71831.1 - 2e-09 37.6 0.0 0.00027 21.2 0.0 5.4 5 1 1 6 6 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 KEY71831.1 - 1.4e-07 31.2 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KEY71831.1 - 2.1e-06 27.6 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein WD40 PF00400.32 KEY71831.1 - 7.2e-05 23.5 0.4 26 5.9 0.0 5.8 6 0 0 6 6 4 0 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 KEY71831.1 - 0.00012 22.7 0.0 0.00034 21.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 KEY71831.1 - 0.00024 21.1 0.0 0.00069 19.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Mcl1_mid PF12341.8 KEY71831.1 - 0.0037 16.7 0.3 0.65 9.3 0.0 3.2 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region LCAT PF02450.15 KEY71831.1 - 0.0045 16.2 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase AAA_19 PF13245.6 KEY71831.1 - 0.0062 16.9 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY71831.1 - 0.01 16.1 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain Thioesterase PF00975.20 KEY71831.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain AAA_16 PF13191.6 KEY71831.1 - 0.022 15.2 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Hydrolase_4 PF12146.8 KEY71831.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY71831.1 - 0.035 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PQQ_2 PF13360.6 KEY71831.1 - 0.04 13.5 0.0 0.21 11.1 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain NTPase_1 PF03266.15 KEY71831.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase Fructosamin_kin PF03881.14 KEY71832.1 - 3.4e-29 102.0 0.0 4.7e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEY71832.1 - 0.0013 18.7 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF659 PF04937.15 KEY71833.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) His_biosynth PF00977.21 KEY71834.1 - 2.9e-30 105.4 0.0 3.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein gag-asp_proteas PF13975.6 KEY71834.1 - 0.083 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ribul_P_3_epim PF00834.19 KEY71834.1 - 0.085 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Anillin PF08174.11 KEY71835.1 - 5.2e-12 46.4 0.0 1.4e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KEY71835.1 - 1.3e-08 35.3 0.0 4.4e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF1899 PF08953.11 KEY71836.1 - 8.2e-35 118.5 0.0 1.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KEY71836.1 - 4.7e-18 64.8 0.2 1e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KEY71836.1 - 9.9e-16 57.9 4.0 0.0001 23.0 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71836.1 - 1.4e-07 31.7 0.7 0.00026 21.2 0.2 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY71836.1 - 0.0098 14.6 0.4 0.39 9.3 0.2 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEY71836.1 - 0.014 14.4 0.0 0.6 9.0 0.0 2.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AlphaC_C PF17480.2 KEY71836.1 - 0.071 13.1 0.1 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 AlphaC C-terminal SOG2 PF10428.9 KEY71836.1 - 4.4 6.4 12.2 6.1 5.9 12.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SlyX PF04102.12 KEY71836.1 - 6.2 7.5 8.3 0.69 10.6 1.5 2.4 2 0 0 2 2 2 0 SlyX TMPIT PF07851.13 KEY71836.1 - 9.4 5.4 6.8 2.1 7.5 0.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein STE PF02200.16 KEY71837.1 - 2.9e-56 188.6 0.1 4.7e-56 187.9 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KEY71837.1 - 0.00074 19.8 4.2 0.0024 18.2 4.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY71837.1 - 0.04 14.8 3.1 0.12 13.3 3.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4602 PF15375.6 KEY71838.1 - 6.5e-08 33.0 12.4 1.1e-06 29.0 12.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Nop25 PF09805.9 KEY71838.1 - 3.1 8.3 14.3 0.052 14.0 3.4 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BCNT PF07572.12 KEY71839.1 - 6.3e-25 87.0 0.5 1.4e-24 86.0 0.5 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 KEY71839.1 - 5.4 5.2 7.3 8 4.6 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KEY71840.1 - 7.6e-10 39.2 13.4 0.0053 17.6 0.4 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71840.1 - 0.0015 18.8 0.0 0.91 9.9 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 KEY71840.1 - 1.8 8.3 15.1 0.53 10.0 10.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SNF2_N PF00176.23 KEY71841.1 - 4.5e-73 246.0 1.3 4.5e-73 246.0 1.3 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY71841.1 - 7.4e-22 77.8 0.3 1.6e-18 67.1 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KEY71841.1 - 1e-20 73.6 0.3 2.6e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KEY71841.1 - 2.3e-16 59.9 15.8 2.3e-16 59.9 15.8 5.1 6 0 0 6 6 6 1 HSA SnAC PF14619.6 KEY71841.1 - 3.7e-15 56.3 1.2 3.7e-15 56.3 1.2 4.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KEY71841.1 - 1.3e-11 44.1 2.7 4.6e-11 42.3 2.7 2.1 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KEY71841.1 - 5.7e-10 39.5 0.0 5.7e-10 39.5 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RBR PF17208.3 KEY71841.1 - 0.00049 20.7 5.5 0.00049 20.7 5.5 3.8 3 2 2 5 5 5 1 RNA binding Region UPF0524 PF15823.5 KEY71841.1 - 3.6 6.9 4.9 8.7 5.7 4.9 1.7 1 0 0 1 1 1 0 UPF0524 of C3orf70 Abhydrolase_6 PF12697.7 KEY71842.1 - 1.1e-07 32.7 0.3 0.0012 19.5 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.13 KEY71842.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KEY71842.1 - 0.022 14.0 0.3 0.053 12.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KEY71842.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PTPLA PF04387.14 KEY71843.1 - 1.4e-56 190.8 12.5 2.5e-56 190.0 12.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DIOX_N PF14226.6 KEY71844.1 - 1.5e-22 80.6 0.0 2.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY71844.1 - 2.9e-19 69.4 0.0 4.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tgi2PP PF18250.1 KEY71844.1 - 0.036 14.3 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP Amidohydro_2 PF04909.14 KEY71845.1 - 2e-32 113.1 0.0 2.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KEY71845.1 - 0.00087 18.7 0.0 0.0037 16.7 0.0 1.9 2 1 0 2 2 2 1 TatD related DNase DnaJ PF00226.31 KEY71846.1 - 2.7e-13 49.8 2.7 5.1e-13 48.9 0.0 2.8 3 0 0 3 3 3 1 DnaJ domain BAF1_ABF1 PF04684.13 KEY71846.1 - 0.072 12.1 7.6 0.11 11.5 7.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC45 PF02724.14 KEY71846.1 - 2.4 6.3 12.1 2.6 6.2 12.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2235 PF09994.9 KEY71847.1 - 7.7e-81 271.6 0.0 1e-80 271.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BppU_IgG PF18667.1 KEY71847.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain GCV_T PF01571.21 KEY71848.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PNISR PF15996.5 KEY71849.1 - 3.6 7.8 8.3 5.7 7.2 8.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DEAD PF00270.29 KEY71850.1 - 1.8e-41 141.9 0.0 1.9e-40 138.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71850.1 - 1.2e-29 102.9 0.0 3.2e-29 101.5 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY71850.1 - 3.9e-06 27.0 0.0 6.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KEY71850.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KEY71850.1 - 0.059 13.0 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Pkinase PF00069.25 KEY71851.1 - 3e-62 210.4 0.0 3.6e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71851.1 - 4.9e-35 121.1 0.0 6.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71851.1 - 9.4e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEY71851.1 - 0.00016 20.6 0.0 0.00023 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEY71851.1 - 0.078 12.6 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TruD PF01142.18 KEY71852.1 - 7.6e-61 206.2 0.1 6.3e-57 193.3 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.17 KEY71853.1 - 7e-08 32.3 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Rotamase_3 PF13616.6 KEY71854.1 - 3.4e-18 66.3 0.8 6.2e-18 65.4 0.1 1.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KEY71854.1 - 1.9e-15 57.6 0.2 4.3e-15 56.4 0.0 1.6 1 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KEY71854.1 - 6.7e-06 26.9 0.4 1.3e-05 26.0 0.0 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.26 KEY71855.1 - 3.3e-28 97.3 0.9 4.2e-28 96.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KEY71855.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ribosomal_S8 PF00410.19 KEY71856.1 - 2.7e-19 69.4 0.0 4.4e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S8 Glyco_transf_90 PF05686.12 KEY71857.1 - 1.8e-16 60.1 10.3 1.7e-12 46.9 8.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Paf1 PF03985.13 KEY71858.1 - 4e-103 345.7 0.8 4.5e-103 345.5 0.8 1.0 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 KEY71859.1 - 1e-76 256.4 10.6 1.2e-76 256.2 10.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF3951 PF13131.6 KEY71859.1 - 2.7 8.3 0.0 2.7 8.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3951) ECH_1 PF00378.20 KEY71860.1 - 2.1e-77 259.9 0.0 2.3e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY71860.1 - 2.8e-34 119.1 0.2 1.3e-33 116.9 0.2 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PALP PF00291.25 KEY71861.1 - 1.4e-66 224.9 0.1 1.9e-66 224.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KEY71861.1 - 1.1e-06 28.4 4.8 1.1e-06 28.4 4.8 5.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KEY71861.1 - 1.6e-05 24.7 0.8 1.6e-05 24.7 0.8 3.8 4 0 0 4 4 4 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KEY71861.1 - 3.2e-05 23.9 4.9 3.2e-05 23.9 4.9 4.5 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY71861.1 - 5.4e-05 22.9 4.1 5.4e-05 22.9 4.1 5.4 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY71861.1 - 7.3e-05 23.0 5.5 7.3e-05 23.0 5.5 5.2 4 2 1 5 5 5 1 Ring finger domain SH3_1 PF00018.28 KEY71861.1 - 0.00028 20.4 0.0 0.00062 19.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_5 PF14634.6 KEY71861.1 - 0.00078 19.4 3.8 0.00078 19.4 3.8 5.5 5 1 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEY71861.1 - 0.00081 19.5 3.7 0.00081 19.5 3.7 4.2 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KEY71861.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain ComZ PF10815.8 KEY71862.1 - 0.0082 16.1 0.4 0.082 12.9 0.3 2.7 3 0 0 3 3 3 1 ComZ Chlam_PMP PF02415.17 KEY71862.1 - 0.078 13.5 0.2 0.24 11.9 0.0 2.0 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ribosomal_L19 PF01245.20 KEY71863.1 - 6.7e-12 45.3 0.1 1.1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 CH PF00307.31 KEY71864.1 - 2.2e-48 163.0 0.2 7.7e-24 84.0 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KEY71864.1 - 4.6e-26 90.7 2.2 1.5e-25 89.0 0.1 2.8 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KEY71864.1 - 1.4e-12 47.2 0.2 1.6e-06 27.8 0.1 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KEY71864.1 - 0.0039 17.0 0.9 0.079 12.9 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KEY71864.1 - 0.0044 16.8 2.2 0.54 10.1 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair CH_2 PF06294.11 KEY71864.1 - 0.014 15.5 0.0 0.54 10.4 0.0 3.1 3 0 0 3 3 3 0 CH-like domain in sperm protein EF-hand_7 PF13499.6 KEY71864.1 - 0.015 15.7 1.5 0.015 15.7 1.5 2.5 3 0 0 3 3 3 0 EF-hand domain pair FAD-oxidase_C PF02913.19 KEY71865.1 - 2.2e-58 197.9 0.0 3.1e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEY71865.1 - 1.6e-36 125.1 0.3 2.9e-36 124.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KEY71866.1 - 9.5e-07 28.8 12.8 2.1e-06 27.7 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KEY71867.1 - 1.1e-54 184.8 0.1 1.7e-54 184.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEY71867.1 - 1.2e-11 44.0 0.4 3.6e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.12 KEY71868.1 - 5.6e-12 46.0 19.6 1.1e-11 45.0 19.6 1.5 1 0 0 1 1 1 1 CHY zinc finger zf-RRPl_C4 PF17026.5 KEY71868.1 - 0.003 17.6 2.0 0.003 17.6 2.0 2.0 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_4 PF13717.6 KEY71868.1 - 5.5 7.0 14.3 1.6 8.7 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 KEY71868.1 - 5.8 7.0 13.3 32 4.6 13.0 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KEY71868.1 - 6.9 6.9 17.4 1.8 8.8 9.4 2.5 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 KEY71868.1 - 7.6 6.9 17.3 3 8.1 0.5 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain ERCC3_RAD25_C PF16203.5 KEY71869.1 - 5.5e-122 405.7 0.1 1e-121 404.8 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KEY71869.1 - 1.6e-34 118.8 0.0 9.1e-34 116.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY71869.1 - 4.8e-15 56.0 0.0 9.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY71869.1 - 2.6e-12 47.1 0.0 6.2e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEY71869.1 - 2.1e-07 30.0 0.0 2.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain TrkH PF02386.16 KEY71871.1 - 3.1e-141 471.2 4.0 3.1e-141 471.2 4.0 1.7 2 0 0 2 2 2 1 Cation transport protein VPS9 PF02204.18 KEY71872.1 - 9.2e-25 86.9 0.0 1.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KEY71872.1 - 0.041 14.2 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) AMP-binding PF00501.28 KEY71873.1 - 2.4e-71 240.6 0.0 3e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY71873.1 - 1.4e-20 74.1 0.4 3.1e-20 72.9 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldo_ket_red PF00248.21 KEY71874.1 - 2.1e-43 148.6 0.0 4.1e-41 141.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 KEY71875.1 - 0.0061 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme BIR PF00653.21 KEY71875.1 - 0.044 14.4 0.0 0.079 13.6 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Glyco_hydro_1 PF00232.18 KEY71876.1 - 2.3e-147 491.1 0.0 2.8e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SBF_like PF13593.6 KEY71877.1 - 7.7e-85 285.0 21.7 9e-85 284.7 21.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Erf4 PF10256.9 KEY71878.1 - 2.7e-38 130.6 0.0 3.9e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4510 PF14971.6 KEY71879.1 - 0.0028 18.0 7.7 0.007 16.7 7.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) Golgin_A5 PF09787.9 KEY71879.1 - 0.012 15.1 1.3 0.02 14.4 1.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Barttin PF15462.6 KEY71879.1 - 0.084 12.6 0.9 0.19 11.5 0.9 1.6 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF1690 PF07956.11 KEY71879.1 - 2 8.9 5.5 5.2 7.5 5.5 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ABC_tran_CTD PF16326.5 KEY71879.1 - 8.6 6.7 9.2 4.4 7.6 5.8 2.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4203 PF13886.6 KEY71880.1 - 3.9e-54 183.4 27.1 5e-54 183.0 27.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) STE3 PF02076.15 KEY71881.1 - 1.2e-62 211.8 15.9 1.9e-62 211.1 15.9 1.3 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.25 KEY71882.1 - 1.3e-17 63.7 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.17 KEY71883.1 - 5.7e-138 459.8 0.0 6.5e-138 459.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KEY71883.1 - 9.7e-33 112.7 0.0 1.9e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KEY71884.1 - 1.8e-43 148.6 0.0 5.1e-43 147.1 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY71884.1 - 5.4e-22 78.2 0.1 1.8e-21 76.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY71884.1 - 7.3e-05 22.8 0.0 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_12 PF13424.6 KEY71885.1 - 5.3e-05 23.4 0.1 0.00015 22.0 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY71885.1 - 0.00036 20.3 5.9 0.8 9.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AF-4 PF05110.13 KEY71885.1 - 0.29 9.2 8.6 0.39 8.7 8.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PNP_UDP_1 PF01048.20 KEY71886.1 - 3.2e-16 59.3 0.2 1.9e-15 56.8 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily bZIP_1 PF00170.21 KEY71887.1 - 0.0021 18.1 5.6 0.0046 17.0 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY71887.1 - 0.0044 17.1 3.5 0.0044 17.1 3.5 1.9 3 0 0 3 3 3 1 Basic region leucine zipper DNA_ligase_A_M PF01068.21 KEY71888.1 - 4.2e-21 75.5 0.0 7.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KEY71888.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA ligase Abhydrolase_3 PF07859.13 KEY71889.1 - 2e-29 103.0 0.5 2.5e-29 102.7 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY71889.1 - 3.1e-11 42.8 0.0 1.1e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KEY71889.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KEY71889.1 - 0.044 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KEY71889.1 - 0.055 12.7 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY71889.1 - 0.073 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KEY71889.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 KEY71889.1 - 0.19 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Chromo PF00385.24 KEY71890.1 - 0.24 11.4 1.7 15 5.6 0.1 2.6 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C48 PF02902.19 KEY71892.1 - 3e-05 24.0 0.2 8.5e-05 22.5 0.2 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain bZIP_1 PF00170.21 KEY71893.1 - 9.8e-05 22.4 6.5 9.8e-05 22.4 6.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY71893.1 - 0.0017 18.4 7.7 0.0031 17.5 7.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Imm1 PF14430.6 KEY71894.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm1 Stealth_CR3 PF17102.5 KEY71895.1 - 0.13 12.2 0.1 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 p450 PF00067.22 KEY71896.1 - 3.8e-45 154.5 0.0 5.1e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEY71897.1 - 0.11 12.6 5.9 0.23 11.6 5.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5484 PF17583.2 KEY71898.1 - 1.9 8.2 6.7 8.4 6.1 1.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5484) HET PF06985.11 KEY71899.1 - 1.4e-10 41.7 4.7 4.8e-10 40.0 1.2 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) peroxidase PF00141.23 KEY71901.1 - 1e-26 94.0 0.0 1.7e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Gly_transf_sug PF04488.15 KEY71902.1 - 1.8e-06 28.5 0.1 5e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif HET PF06985.11 KEY71904.1 - 2.9e-12 47.2 6.3 4.4e-10 40.1 0.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY71904.1 - 2.4e-11 44.1 0.2 1.9e-08 34.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY71904.1 - 1.7e-07 31.7 0.3 4.5e-07 30.3 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY71904.1 - 2.2e-06 27.5 0.6 0.00057 20.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KEY71904.1 - 9.3e-05 22.6 0.1 0.00059 20.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KEY71904.1 - 0.005 17.2 1.6 0.092 13.2 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat COesterase PF00135.28 KEY71905.1 - 1.8e-61 208.6 0.0 2.3e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY71905.1 - 9.1e-07 28.9 0.1 3.6e-06 27.0 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4265 PF14085.6 KEY71905.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) AAA_16 PF13191.6 KEY71906.1 - 1.9e-07 31.7 0.0 0.00032 21.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KEY71906.1 - 3.3e-07 30.4 0.0 1.5e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.14 KEY71906.1 - 0.0013 18.0 0.2 0.46 9.7 0.1 3.5 4 0 0 4 4 4 1 KAP family P-loop domain Ank_2 PF12796.7 KEY71906.1 - 0.0015 19.1 0.1 0.5 11.0 0.0 3.5 1 1 1 3 3 3 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 KEY71906.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain NACHT_N PF17100.5 KEY71906.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase FliN_N PF16973.5 KEY71906.1 - 0.041 13.7 0.3 0.12 12.2 0.3 1.8 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal UspB PF10625.9 KEY71906.1 - 0.043 13.8 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Universal stress protein B (UspB) ATPase_2 PF01637.18 KEY71906.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KEY71906.1 - 0.09 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KR PF08659.10 KEY71907.1 - 9.9e-25 87.5 0.1 1.7e-24 86.7 0.0 1.5 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 KEY71907.1 - 0.0057 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Fungal_trans PF04082.18 KEY71908.1 - 9.1e-11 41.3 0.0 2.4e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.8 KEY71909.1 - 1.3e-19 70.9 0.5 2.3e-16 60.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KEY71910.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.18 KEY71911.1 - 8.9e-08 31.5 0.0 1.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.6 KEY71911.1 - 0.033 14.5 0.7 0.15 12.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_holin_3_7 PF05449.11 KEY71911.1 - 0.052 13.6 0.4 0.59 10.2 0.1 2.4 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 TPR_1 PF00515.28 KEY71911.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3328 PF11807.8 KEY71912.1 - 4.5e-17 62.6 6.7 7.9e-17 61.8 2.5 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF3328) adh_short PF00106.25 KEY71914.1 - 1.1e-23 83.8 0.5 1.3e-23 83.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71914.1 - 4.7e-22 78.7 0.9 1.2e-21 77.4 0.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71914.1 - 7.6e-17 61.8 0.2 1e-16 61.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY71914.1 - 6.7e-07 28.7 0.1 9e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KEY71915.1 - 6.3e-38 130.6 18.8 6.3e-38 130.6 18.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KEY71915.1 - 1e-05 25.0 0.1 1e-05 25.0 0.1 3.3 2 1 2 4 4 4 1 Uncharacterised MFS-type transporter YbfB CLN3 PF02487.17 KEY71915.1 - 0.092 11.8 7.1 0.063 12.3 0.6 2.2 2 0 0 2 2 2 0 CLN3 protein CBM_6 PF03422.15 KEY71916.1 - 3.3e-09 37.1 0.2 5e-09 36.5 0.2 1.3 1 1 0 1 1 1 1 Carbohydrate binding module (family 6) Phage_r1t_holin PF16945.5 KEY71916.1 - 0.014 15.6 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Peptidase_S9 PF00326.21 KEY71917.1 - 2.7e-05 23.7 0.7 4.7e-05 23.0 0.4 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KEY71917.1 - 2.8e-05 23.7 0.7 0.00031 20.3 0.1 2.3 1 1 2 3 3 3 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KEY71917.1 - 0.0044 16.9 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KEY71917.1 - 0.086 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KEY71917.1 - 0.14 11.8 0.1 0.22 11.1 0.1 1.5 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 KEY71917.1 - 0.17 10.6 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RTA1 PF04479.13 KEY71918.1 - 4e-62 209.5 7.3 5.1e-62 209.1 7.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Myb_DNA-binding PF00249.31 KEY71919.1 - 1.3e-34 118.1 12.5 5.6e-13 48.8 0.3 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY71919.1 - 2.7e-31 107.6 2.6 6e-15 55.2 0.1 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KEY71919.1 - 1.3e-06 28.2 0.1 0.0026 17.6 0.0 3.5 3 1 0 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 KEY71919.1 - 0.0011 19.0 3.7 0.8 9.8 0.8 3.4 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KEY71919.1 - 0.014 15.5 0.1 1.3 9.3 0.0 2.6 1 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 HEPN_RES_NTD1 PF18870.1 KEY71919.1 - 0.044 14.0 1.1 0.062 13.5 0.1 1.8 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 SLIDE PF09111.10 KEY71919.1 - 0.16 12.0 0.1 5.3 7.1 0.1 2.9 1 1 0 2 2 2 0 SLIDE p450 PF00067.22 KEY71920.1 - 3.5e-57 194.2 0.0 2.6e-56 191.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KEY71921.1 - 4e-80 269.0 0.0 6.8e-80 268.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY71921.1 - 5.1e-50 170.8 0.0 4.7e-49 167.6 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY71921.1 - 1.1e-34 119.0 0.1 3e-34 117.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KEY71921.1 - 8.9e-27 94.4 0.2 1.8e-21 77.0 0.0 3.3 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KEY71921.1 - 2.2e-22 79.2 2.3 3e-11 43.5 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KEY71921.1 - 3.8e-21 75.6 0.0 6.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KEY71921.1 - 3.7e-19 69.7 0.2 3.2e-18 66.7 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KEY71921.1 - 3.2e-09 37.2 0.0 8.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KEY71921.1 - 1.7e-06 28.8 0.0 0.0002 22.1 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KEY71921.1 - 0.00054 19.4 0.2 0.0013 18.1 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 KEY71921.1 - 0.0049 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KEY71921.1 - 0.02 14.8 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KEY71921.1 - 0.044 13.5 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KEY71921.1 - 0.057 12.9 0.3 0.099 12.1 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ACP_syn_III PF08545.10 KEY71921.1 - 0.06 13.2 0.5 0.28 11.1 0.5 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 KEY71922.1 - 6e-37 127.2 0.0 2.3e-36 125.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KEY71922.1 - 4e-15 55.7 0.0 6.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KEY71922.1 - 0.00028 21.2 0.0 0.003 17.9 0.0 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KEY71922.1 - 0.0012 18.3 0.1 0.02 14.3 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PTR2 PF00854.21 KEY71923.1 - 1.1e-72 245.0 7.2 1.5e-72 244.6 7.2 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KEY71923.1 - 2.7e-07 29.8 18.3 2.7e-07 29.8 18.3 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ERG2_Sigma1R PF04622.12 KEY71924.1 - 1e-97 325.5 0.1 1.2e-97 325.3 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NPCC PF08058.11 KEY71926.1 - 1e-25 90.3 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component DUF410 PF04190.13 KEY71927.1 - 2.5e-92 309.3 0.0 3e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UPF0220 PF05255.11 KEY71928.1 - 7.7e-65 217.5 3.5 1.1e-64 217.0 3.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) BNIP3 PF06553.12 KEY71928.1 - 0.029 14.1 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 BNIP3 Tim54 PF11711.8 KEY71929.1 - 0.022 13.6 0.6 0.033 13.0 0.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3c_N PF05470.12 KEY71929.1 - 0.11 10.8 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 KEY71929.1 - 0.17 10.2 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 KEY71929.1 - 0.28 9.9 1.6 0.4 9.4 1.6 1.1 1 0 0 1 1 1 0 Raftlin RNA_pol_Rpc4 PF05132.14 KEY71929.1 - 1.3 9.5 5.8 2.5 8.5 5.8 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KEY71929.1 - 1.9 7.2 7.8 3 6.5 7.8 1.2 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 KEY71929.1 - 2.6 6.4 9.4 7 4.9 9.6 1.3 1 1 0 1 1 1 0 Membrane transport protein ABC_membrane PF00664.23 KEY71930.1 - 2.2e-54 185.0 35.0 3.1e-36 125.4 16.0 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY71930.1 - 1.3e-46 158.5 0.0 5.1e-27 95.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KEY71930.1 - 1e-05 25.5 2.3 0.047 13.8 0.4 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KEY71930.1 - 2.7e-05 23.7 0.8 1.1 8.7 0.2 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY71930.1 - 5.6e-05 23.6 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEY71930.1 - 0.00019 21.3 0.3 1.8 8.3 0.1 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY71930.1 - 0.00035 20.3 2.3 0.3 10.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY71930.1 - 0.0016 18.3 1.3 0.56 10.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KEY71930.1 - 0.0018 17.6 0.1 0.29 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 KEY71930.1 - 0.0025 16.8 1.7 0.71 8.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KEY71930.1 - 0.0047 17.1 3.2 0.27 11.3 0.8 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KEY71930.1 - 0.01 16.1 3.5 2.8 8.2 0.2 3.3 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KEY71930.1 - 0.017 14.4 0.1 0.044 13.0 0.0 1.7 2 0 0 2 2 1 0 KAP family P-loop domain Ploopntkinase3 PF18751.1 KEY71930.1 - 0.022 14.7 0.2 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 EMC3_TMCO1 PF01956.16 KEY71930.1 - 0.022 14.5 0.4 0.64 9.7 0.2 2.8 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Dynamin_N PF00350.23 KEY71930.1 - 0.022 14.8 5.8 0.078 13.0 0.2 3.0 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.6 KEY71930.1 - 0.023 14.4 1.8 3.8 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KEY71930.1 - 0.035 13.0 0.9 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KEY71930.1 - 0.047 14.2 0.0 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KEY71930.1 - 0.084 13.1 0.2 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dimer_Tnp_hAT PF05699.14 KEY71930.1 - 0.11 12.3 0.7 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region IstB_IS21 PF01695.17 KEY71930.1 - 0.11 12.2 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KEY71930.1 - 0.13 11.8 0.4 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KEY71930.1 - 0.14 11.9 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KEY71930.1 - 0.15 11.4 0.0 19 4.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KEY71930.1 - 0.36 10.6 3.3 20 4.8 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KEY71930.1 - 0.54 10.5 2.7 0.92 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KEY71930.1 - 1.1 9.7 8.2 3.7 8.0 0.1 3.1 4 0 0 4 4 2 0 AAA domain S_4TM PF18159.1 KEY71930.1 - 7 5.9 6.4 7.1 5.8 0.0 3.1 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain EXOSC1 PF10447.9 KEY71931.1 - 1.1e-18 67.9 5.1 1.5e-13 51.3 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KEY71931.1 - 3.7e-10 39.4 0.9 8e-10 38.4 0.9 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Sec2p PF06428.11 KEY71932.1 - 1.5e-11 44.1 9.5 1.5e-11 44.1 9.5 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p CCDC53 PF10152.9 KEY71932.1 - 0.0067 16.8 13.0 0.043 14.2 0.3 2.9 2 1 1 3 3 3 2 Subunit CCDC53 of WASH complex Atg14 PF10186.9 KEY71932.1 - 0.0075 15.4 9.7 0.75 8.8 10.8 2.2 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Noelin-1 PF12308.8 KEY71932.1 - 0.01 15.8 0.4 0.12 12.4 0.0 2.5 2 1 1 3 3 3 0 Neurogenesis glycoprotein HAUS6_N PF14661.6 KEY71932.1 - 0.74 9.4 8.6 12 5.4 8.8 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 KEY71932.1 - 2.9 8.1 28.5 0.23 11.7 13.3 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 KEY71932.1 - 4.2 5.2 7.7 37 2.0 9.5 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KEY71932.1 - 5.7 6.4 13.6 16 4.9 13.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 KEY71932.1 - 6.1 6.9 17.5 24 5.0 11.3 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 KEY71932.1 - 9.3 6.1 6.1 7.5 6.4 0.0 2.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD CorA PF01544.18 KEY71932.1 - 9.9 5.4 12.1 23 4.2 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TruB_N PF01509.18 KEY71933.1 - 3.5e-45 154.0 0.0 8.7e-45 152.7 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KEY71933.1 - 1.8e-06 28.0 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Glyco_hydro_62 PF03664.13 KEY71934.1 - 4.4e-149 495.2 13.5 5.1e-149 495.0 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DNMT1-RFD PF12047.8 KEY71935.1 - 0.00038 20.5 0.0 0.00084 19.4 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain QWRF PF04484.12 KEY71935.1 - 6.8 6.3 7.5 13 5.4 7.5 1.3 1 0 0 1 1 1 0 QWRF family MIF4G_like PF09088.11 KEY71936.1 - 7e-84 280.4 0.0 1.1e-83 279.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KEY71936.1 - 1.7e-70 237.5 0.0 2.7e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G like Pkinase PF00069.25 KEY71937.1 - 6.4e-59 199.5 0.0 1.5e-57 195.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY71937.1 - 1.4e-20 73.7 0.0 3.4e-20 72.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY71937.1 - 4.2e-05 23.0 0.0 0.00019 20.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KEY71937.1 - 0.003 17.5 0.0 0.011 15.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KEY71937.1 - 0.031 14.5 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Seadorna_VP7 PF07387.11 KEY71937.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KEY71937.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.6 KEY71939.1 - 5.6e-20 71.8 0.0 7.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY71939.1 - 3.4e-15 56.5 0.0 9.3e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY71939.1 - 2.4e-13 50.7 0.0 1.1e-12 48.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY71939.1 - 8.7e-13 48.7 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY71939.1 - 6.4e-12 45.5 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY71939.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KEY71939.1 - 0.00094 19.0 0.0 0.0017 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF938) DREV PF05219.12 KEY71939.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 KEY71939.1 - 0.003 16.6 0.0 0.0039 16.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.9 KEY71939.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KEY71939.1 - 0.0089 15.8 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEY71939.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_33 PF10017.9 KEY71939.1 - 0.042 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CMAS PF02353.20 KEY71939.1 - 0.057 12.7 0.0 0.064 12.5 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KEY71939.1 - 0.059 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 KEY71939.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 KEY71939.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MIOX PF05153.15 KEY71940.1 - 3.3e-121 403.6 0.1 4.1e-121 403.2 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase YfiO PF13525.6 KEY71940.1 - 0.023 14.4 1.3 0.023 14.4 1.3 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein Caleosin PF05042.13 KEY71940.1 - 0.029 14.3 0.1 0.058 13.3 0.1 1.5 1 1 0 1 1 1 0 Caleosin related protein HD PF01966.22 KEY71940.1 - 0.084 13.1 0.1 2.6 8.3 0.0 2.6 3 0 0 3 3 3 0 HD domain Fungal_trans_2 PF11951.8 KEY71941.1 - 9.7e-08 31.2 3.1 9.7e-08 31.2 3.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY71942.1 - 2.2e-09 37.3 10.9 2.2e-09 37.3 10.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY71942.1 - 0.012 14.7 0.7 0.019 14.0 0.7 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 KEY71943.1 - 5e-49 167.3 0.0 6.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ferritin_2 PF13668.6 KEY71945.1 - 2.2e-42 144.5 1.8 2.2e-42 144.5 1.8 1.6 2 0 0 2 2 2 1 Ferritin-like domain FAD_binding_4 PF01565.23 KEY71946.1 - 8.7e-18 64.4 1.2 1.6e-17 63.6 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY71946.1 - 0.037 14.1 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Myb_DNA-binding PF00249.31 KEY71948.1 - 1.1e-34 118.3 7.3 3e-14 52.9 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY71948.1 - 2.3e-28 98.2 1.4 3.5e-12 46.4 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KEY71948.1 - 0.00046 20.0 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KEY71948.1 - 0.0045 17.1 0.8 0.3 11.3 0.0 3.2 3 1 0 3 3 3 1 Rap1 Myb domain MADF_DNA_bdg PF10545.9 KEY71948.1 - 0.0061 16.9 5.0 7.8 6.9 0.1 3.3 2 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 KEY71948.1 - 0.0077 16.4 0.0 4.9 7.4 0.0 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 KEY71948.1 - 0.057 13.8 4.0 5.9 7.3 0.0 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain FAD_binding_3 PF01494.19 KEY71949.1 - 2e-33 116.1 0.1 2.3e-32 112.6 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY71949.1 - 1.4e-09 37.7 0.7 1.6e-06 27.6 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY71949.1 - 7.5e-07 29.0 2.0 1e-05 25.3 0.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY71949.1 - 3.9e-06 27.0 0.2 1.3e-05 25.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY71949.1 - 5e-06 26.0 0.9 0.00075 18.8 0.2 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY71949.1 - 3.9e-05 23.1 0.0 0.19 11.0 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEY71949.1 - 6.9e-05 23.3 0.3 0.00092 19.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY71949.1 - 0.00013 21.2 0.1 0.079 12.0 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KEY71949.1 - 0.00016 20.5 0.1 0.0025 16.6 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KEY71949.1 - 0.00075 18.8 0.1 0.0016 17.7 0.1 1.5 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 KEY71949.1 - 0.0021 18.3 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 KEY71949.1 - 0.0046 16.1 0.7 0.008 15.3 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KEY71949.1 - 0.0052 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEY71949.1 - 0.009 16.4 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KEY71949.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KEY71949.1 - 0.062 12.6 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEY71949.1 - 0.067 12.3 0.2 0.1 11.6 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KEY71949.1 - 0.09 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KEY71949.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KEY71949.1 - 0.24 11.0 0.1 0.37 10.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 KEY71950.1 - 7.3e-20 71.3 0.0 5.3e-16 58.7 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY71950.1 - 2.7e-11 43.5 0.0 3.3e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY71950.1 - 1.5e-05 25.0 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY71950.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY71950.1 - 0.0033 17.7 0.1 0.008 16.4 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KEY71950.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEY71950.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KEY71951.1 - 8.1e-38 130.3 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lant_dehydr_N PF04738.13 KEY71951.1 - 0.047 11.8 0.2 0.16 10.0 0.1 1.7 1 1 0 2 2 2 0 Lantibiotic dehydratase, N terminus Arylsulfotrans PF05935.11 KEY71952.1 - 1.4e-19 70.3 0.0 3.4e-08 32.8 0.0 3.3 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KEY71952.1 - 5e-14 52.4 0.0 1.1e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KEY71952.1 - 0.00014 21.5 0.0 0.00051 19.7 0.0 1.9 2 0 0 2 2 2 1 PQQ-like domain MFS_1 PF07690.16 KEY71953.1 - 1.4e-33 116.3 29.4 2.1e-33 115.7 29.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KEY71954.1 - 2.7e-05 24.2 8.0 5.3e-05 23.2 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KEY71955.1 - 2.9e-34 118.8 0.0 4.9e-33 114.8 0.0 2.0 2 0 0 2 2 2 2 Amidase Lipase_GDSL PF00657.22 KEY71956.1 - 7e-12 45.7 0.0 9.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KEY71956.1 - 6.3e-06 26.7 2.3 1.3e-05 25.6 2.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GFO_IDH_MocA PF01408.22 KEY71958.1 - 1e-19 71.5 0.0 2e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEY71958.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 KEY71961.1 - 4e-21 75.2 7.8 4e-21 75.2 7.8 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KEY71961.1 - 4.9e-14 52.2 0.0 9.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KEY71963.1 - 3.2e-17 62.6 2.2 5.3e-17 61.9 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY71963.1 - 0.021 14.9 0.4 0.043 13.9 0.4 1.6 1 0 0 1 1 1 0 Berberine and berberine like DUF746 PF05344.11 KEY71963.1 - 0.17 11.7 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) NAD_binding_10 PF13460.6 KEY71964.1 - 2.9e-08 33.8 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY71964.1 - 3.2e-06 26.8 0.0 0.017 14.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KEY71964.1 - 3.8e-05 24.1 0.1 7.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEY71964.1 - 0.0025 16.9 0.0 0.009 15.0 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEY71964.1 - 0.06 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 KEY71965.1 - 3.5e-37 128.3 0.9 4e-37 128.0 0.9 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA_lid_4 PF17864.1 KEY71965.1 - 0.044 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain Babuvirus_MP PF07234.11 KEY71965.1 - 0.15 12.2 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Movement and RNA silencing protein Transferase PF02458.15 KEY71966.1 - 4e-07 29.1 0.0 3.1e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Transferase family Pkinase_Tyr PF07714.17 KEY71967.1 - 2.1e-08 33.8 0.0 3e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY71967.1 - 7.6e-08 32.0 0.0 8.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KEY71967.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF587 PF04532.12 KEY71967.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) RIO1 PF01163.22 KEY71967.1 - 0.22 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CBM_1 PF00734.18 KEY71968.1 - 7.5e-13 48.2 9.5 2.8e-12 46.4 9.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain AXE1 PF05448.12 KEY71968.1 - 0.003 16.3 0.1 0.0046 15.7 0.1 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Glyco_hydro_11 PF00457.17 KEY71969.1 - 3.5e-73 245.0 17.8 4.1e-73 244.8 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Amelotin PF15757.5 KEY71969.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Amelotin Abhydrolase_6 PF12697.7 KEY71970.1 - 1.5e-07 32.2 0.8 5.1e-07 30.5 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.12 KEY71970.1 - 5.4e-06 26.4 1.8 0.082 12.8 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KEY71970.1 - 0.0006 20.2 0.1 0.0024 18.3 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 KEY71970.1 - 0.008 15.9 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 PGAP1-like protein ATPase PF06745.13 KEY71970.1 - 0.019 14.3 0.5 4.5 6.6 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 KEY71970.1 - 0.032 14.5 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 KEY71970.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KEY71970.1 - 0.056 12.7 0.0 0.22 10.8 0.0 2.0 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PIF1 PF05970.14 KEY71970.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF3089 PF11288.8 KEY71970.1 - 0.074 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Ofd1_CTDD PF10637.9 KEY71970.1 - 0.079 12.3 0.3 0.16 11.2 0.3 1.5 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term AAA_25 PF13481.6 KEY71970.1 - 0.13 11.9 3.4 0.44 10.1 1.3 2.8 2 1 0 2 2 2 0 AAA domain Gemini_mov PF01708.16 KEY71971.1 - 0.017 14.8 1.1 0.03 14.1 1.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein MFS_1 PF07690.16 KEY71973.1 - 1e-29 103.6 36.0 4.3e-27 95.0 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY71973.1 - 2.9e-09 36.3 19.5 4.5e-05 22.5 4.2 2.0 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 KEY71973.1 - 0.00027 19.4 3.7 0.00027 19.4 3.7 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KEY71973.1 - 0.0056 15.6 17.4 0.012 14.5 17.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KEY71973.1 - 0.44 8.9 11.9 0.0097 14.4 4.5 1.9 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4396 PF14342.6 KEY71974.1 - 4.7e-45 153.4 4.0 6.4e-45 153.0 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) uDENN PF03456.18 KEY71976.1 - 0.11 13.2 0.7 0.19 12.5 0.7 1.4 1 1 0 1 1 1 0 uDENN domain WD40 PF00400.32 KEY71978.1 - 3.1e-101 328.4 46.8 6.1e-11 42.7 0.3 9.8 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY71978.1 - 2.6e-33 114.2 3.5 0.0048 17.2 0.0 9.4 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY71978.1 - 9.1e-18 64.7 0.0 1.7e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KEY71978.1 - 9.9e-13 47.7 14.4 0.014 14.3 0.1 7.4 1 1 7 8 8 8 8 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KEY71978.1 - 1.4e-11 43.5 4.6 0.025 13.1 0.0 4.5 1 1 5 6 6 6 6 Cytochrome D1 heme domain HET PF06985.11 KEY71978.1 - 1.6e-10 41.5 9.0 6.8e-09 36.2 0.3 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Nup160 PF11715.8 KEY71978.1 - 3e-09 36.1 8.2 6.8 5.2 0.0 8.6 2 1 7 9 9 9 5 Nucleoporin Nup120/160 PUA_3 PF17785.1 KEY71978.1 - 3.1e-07 30.1 1.8 54 3.7 0.0 8.5 9 0 0 9 9 9 0 PUA-like domain POT1 PF02765.17 KEY71978.1 - 0.0028 17.5 4.3 14 5.5 0.0 5.6 2 1 4 7 7 7 1 Telomeric single stranded DNA binding POT1/CDC13 Nucleolin_bd PF16725.5 KEY71978.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Nucleolin binding domain Beta-APP PF03494.13 KEY71979.1 - 4.1 7.3 9.5 7.6 6.5 0.9 2.8 1 1 2 3 3 3 0 Beta-amyloid peptide (beta-APP) Calponin PF00402.18 KEY71979.1 - 5.2 6.8 5.4 5.9 6.6 1.1 2.3 2 0 0 2 2 2 0 Calponin family repeat Recep_L_domain PF01030.24 KEY71981.1 - 0.0021 18.2 13.1 0.76 9.9 3.3 4.6 1 1 2 3 3 3 3 Receptor L domain LRR_5 PF13306.6 KEY71981.1 - 0.026 14.5 2.1 0.055 13.4 0.4 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) G-patch PF01585.23 KEY71982.1 - 2.5e-13 49.7 0.0 2.5e-13 49.7 0.0 2.0 3 0 0 3 3 3 1 G-patch domain RRM_1 PF00076.22 KEY71982.1 - 1e-05 25.3 0.1 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KEY71983.1 - 1.1e-33 116.5 0.0 1.3e-32 113.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY71983.1 - 1.4e-24 86.5 0.0 3.5e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KEY71983.1 - 0.0014 18.9 0.0 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KEY71983.1 - 0.0042 17.1 0.0 0.0088 16.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEY71983.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY71983.1 - 0.028 14.7 0.2 0.49 10.7 0.2 2.5 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 KEY71983.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PrpR_N PF06506.11 KEY71983.1 - 0.14 11.7 0.0 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Propionate catabolism activator Ribosomal_L22e PF01776.17 KEY71985.1 - 6.1e-45 152.1 0.7 7.5e-45 151.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.27 KEY71986.1 - 2.7e-53 177.9 0.1 6.9e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SARAF PF06682.12 KEY71988.1 - 0.0028 17.4 0.0 0.0033 17.1 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 KEY71988.1 - 0.0036 18.0 1.1 0.0062 17.2 1.1 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.6 KEY71988.1 - 0.039 13.7 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 KEY71988.1 - 0.083 13.8 0.1 0.1 13.5 0.1 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pox_A9 PF04835.12 KEY71988.1 - 0.12 12.5 0.3 0.17 12.0 0.3 1.1 1 0 0 1 1 1 0 A9 protein conserved region DUF4834 PF16118.5 KEY71988.1 - 0.17 12.9 0.0 0.23 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CcmH PF03918.14 KEY71988.1 - 0.2 10.9 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Shisa PF13908.6 KEY71988.1 - 1.2 9.3 3.4 1.8 8.8 3.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Tfb5 PF06331.12 KEY71989.1 - 7.1e-26 90.0 0.9 7.7e-26 89.9 0.9 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 KEY71990.1 - 1.2e-36 126.4 0.2 2e-36 125.6 0.2 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEY71990.1 - 6.7e-29 101.4 0.0 1e-26 94.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF2188 PF09954.9 KEY71990.1 - 0.16 12.2 0.3 0.33 11.1 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Glyco_hydro_72 PF03198.14 KEY71991.1 - 2e-124 414.9 2.6 2.5e-124 414.6 2.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KEY71991.1 - 3.9e-07 29.8 0.8 1.2e-05 25.0 0.8 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxysterol_BP PF01237.18 KEY71992.1 - 3.5e-108 361.8 0.0 1.1e-107 360.1 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KEY71992.1 - 1.1e-37 128.2 1.1 4.7e-37 126.1 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KEY71992.1 - 3.1e-07 30.8 0.1 1.2e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 KEY71992.1 - 0.044 13.5 0.4 0.49 10.2 0.2 2.4 2 0 0 2 2 2 0 PH domain ArfGap PF01412.18 KEY71993.1 - 6.5e-38 129.4 1.9 1.2e-37 128.5 1.9 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KEY71993.1 - 0.12 12.3 0.5 0.34 10.8 0.1 2.1 2 1 0 2 2 2 0 UBA/TS-N domain ODC_AZ PF02100.17 KEY71994.1 - 8e-44 148.3 0.1 1.1e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.21 KEY71995.1 - 1.8e-49 168.2 0.7 7.6e-49 166.2 0.7 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KEY71995.1 - 5.2e-21 75.3 0.0 8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KEY71995.1 - 4.1e-08 33.3 0.0 5.6e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KEY71995.1 - 1.4e-06 28.1 0.1 7.4e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KEY71995.1 - 0.018 14.8 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.17 KEY71995.1 - 0.023 13.8 0.1 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TFIIIC_sub6 PF10419.9 KEY71996.1 - 2.2e-19 69.1 0.0 3.3e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KEY71997.1 - 3.1e-12 45.6 0.4 5.3e-12 44.8 0.4 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF5082 PF16888.5 KEY71998.1 - 0.11 12.7 1.5 1.6 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Trimer_CC PF08954.11 KEY71998.1 - 0.18 11.4 0.0 0.18 11.4 0.0 3.3 3 0 0 3 3 3 0 Trimerisation motif CorA PF01544.18 KEY71998.1 - 3.5 6.9 8.2 2.7 7.2 1.4 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Ribosomal_L16 PF00252.18 KEY72001.1 - 1.2e-45 154.7 0.0 1.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 KEY72002.1 - 9.6e-23 79.7 0.0 1.1e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3450 PF11932.8 KEY72003.1 - 0.15 11.4 25.5 0.43 9.8 19.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Nipped-B_C PF12830.7 KEY72003.1 - 0.61 10.0 2.8 1.2 9.1 2.8 1.4 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus AAA_13 PF13166.6 KEY72003.1 - 2 6.9 18.0 3.5 6.1 18.0 1.4 1 0 0 1 1 1 0 AAA domain DotU PF09850.9 KEY72003.1 - 2.4 7.8 6.7 10 5.8 1.9 2.9 3 0 0 3 3 3 0 Type VI secretion system protein DotU FliG_N PF14842.6 KEY72003.1 - 2.6 8.6 14.7 2.3 8.8 2.0 3.4 3 0 0 3 3 3 0 FliG N-terminal domain DUF4735 PF15882.5 KEY72003.1 - 3.8 6.9 6.4 7.1 6.0 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) V_ATPase_I PF01496.19 KEY72003.1 - 5.6 4.8 14.5 6.9 4.4 12.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KEY72003.1 - 5.7 6.1 13.9 14 4.9 13.7 1.7 1 1 0 1 1 1 0 TMPIT-like protein NopRA1 PF16201.5 KEY72003.1 - 7.6 6.1 6.3 30 4.1 6.3 2.0 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Vac7 PF12751.7 KEY72004.1 - 2.8e-155 517.5 1.9 2.8e-155 517.5 1.9 2.2 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 RrnaAD PF00398.20 KEY72005.1 - 2.6e-63 213.6 0.0 3.5e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KEY72005.1 - 7e-07 29.9 0.0 1.6e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72005.1 - 2e-05 25.1 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEY72005.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KEY72005.1 - 0.0031 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KEY72005.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY72005.1 - 0.005 17.6 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY72005.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEY72005.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain AAA_lid_4 PF17864.1 KEY72005.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain PRP1_N PF06424.12 KEY72006.1 - 2.3e-50 170.9 10.1 5.7e-50 169.6 10.1 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KEY72006.1 - 1.5e-31 108.7 15.9 1.1e-07 32.2 0.2 9.8 6 3 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEY72006.1 - 1.1e-29 100.5 37.7 0.00011 22.7 0.2 14.6 6 3 9 15 15 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 KEY72006.1 - 4.1e-14 53.0 18.4 0.00018 22.1 0.7 8.2 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 KEY72006.1 - 6.6e-13 48.1 8.5 0.29 11.6 0.0 10.7 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY72006.1 - 5.1e-12 44.9 15.2 0.013 15.6 0.0 9.8 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY72006.1 - 1.2e-10 40.7 5.7 0.0026 17.8 0.0 7.7 11 0 0 11 11 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY72006.1 - 7.8e-07 28.7 2.6 0.99 9.1 0.0 6.4 6 1 1 7 7 7 2 TPR repeat TPR_21 PF09976.9 KEY72006.1 - 1.2e-06 28.4 14.4 0.0086 15.8 0.1 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KEY72006.1 - 2.5e-06 27.1 1.0 0.07 13.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEY72006.1 - 4.1e-06 26.8 11.2 0.00055 20.0 0.1 6.1 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY72006.1 - 3.2e-05 24.3 6.0 23 5.9 0.0 8.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY72006.1 - 4e-05 23.8 1.1 9.3 6.6 0.0 5.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KEY72006.1 - 5.5e-05 22.3 9.6 1.3 7.8 0.0 5.7 3 1 3 6 6 6 3 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KEY72006.1 - 0.00042 20.1 0.3 0.71 10.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEY72006.1 - 0.0005 19.4 27.2 0.05 12.8 5.3 6.6 2 2 4 6 6 6 2 Tetratricopeptide repeat DUF3808 PF10300.9 KEY72006.1 - 0.0011 17.8 0.4 2.6 6.7 0.0 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) Suf PF05843.14 KEY72006.1 - 0.0014 18.7 0.0 6.8 6.6 0.0 3.8 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) KdpC PF02669.15 KEY72006.1 - 0.0016 18.3 0.8 0.0037 17.1 0.8 1.6 1 0 0 1 1 1 1 K+-transporting ATPase, c chain ZNRF_3_ecto PF18212.1 KEY72006.1 - 0.021 14.8 0.6 7.9 6.5 0.0 4.2 4 1 1 5 5 5 0 ZNRF-3 Ectodomain Wzy_C_2 PF11846.8 KEY72006.1 - 0.14 12.0 5.0 16 5.4 0.0 4.5 3 2 3 6 6 6 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 KEY72006.1 - 1.3 9.4 15.0 3.4 8.0 0.0 6.1 6 1 1 7 7 4 0 Tetratricopeptide repeat CDC27 PF09507.10 KEY72006.1 - 4.5 6.6 10.6 8.4 5.7 10.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pex24p PF06398.11 KEY72009.1 - 0.00044 19.4 7.7 0.00083 18.4 7.7 1.5 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PFO_beta_C PF12367.8 KEY72009.1 - 0.12 12.6 0.1 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal PP2C PF00481.21 KEY72010.1 - 2.5e-84 282.9 0.0 4.6e-84 282.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEY72010.1 - 0.01 15.7 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) He_PIG PF05345.12 KEY72011.1 - 8.5e-14 51.5 8.5 0.0021 18.2 0.8 4.2 3 0 0 3 3 3 3 Putative Ig domain FXR_C1 PF16096.5 KEY72011.1 - 0.87 9.8 6.0 8 6.7 0.0 3.4 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 Methyltransf_16 PF10294.9 KEY72012.1 - 6.2e-44 149.8 0.0 7.7e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KEY72012.1 - 0.0002 21.2 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY72012.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KEY72012.1 - 0.026 15.2 0.0 0.045 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEY72012.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KEY72012.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2947 PF11163.8 KEY72012.1 - 0.16 11.8 0.2 0.23 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PrmA PF06325.13 KEY72012.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Calcipressin PF04847.12 KEY72012.1 - 1.9 8.2 3.8 9.5 5.9 0.3 2.2 2 0 0 2 2 2 0 Calcipressin DPBB_1 PF03330.18 KEY72013.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Lytic transglycolase PRCC PF10253.9 KEY72013.1 - 0.08 13.7 6.4 0.1 13.4 6.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CarboxypepD_reg PF13620.6 KEY72013.1 - 0.16 12.3 1.8 11 6.3 0.3 2.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CCDC53 PF10152.9 KEY72013.1 - 3.9 7.9 10.2 19 5.6 10.2 1.9 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1712 PF08217.11 KEY72014.1 - 1.4e-12 46.9 0.0 1.4e-11 43.6 0.0 2.3 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) CorA PF01544.18 KEY72015.1 - 0.00076 18.9 3.7 0.0024 17.3 3.7 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2681 PF10883.8 KEY72015.1 - 0.0019 18.5 0.2 0.0067 16.8 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) PspB PF06667.12 KEY72015.1 - 0.0026 17.8 0.5 0.0061 16.6 0.5 1.6 1 0 0 1 1 1 1 Phage shock protein B CcmD PF04995.14 KEY72015.1 - 0.025 14.6 0.8 0.088 12.9 0.8 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KEY72015.1 - 0.042 14.1 0.4 0.099 12.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HTH_Tnp_IS630 PF01710.16 KEY72015.1 - 0.75 9.9 4.1 7.5 6.6 0.1 2.6 3 0 0 3 3 3 0 Transposase Kelch_6 PF13964.6 KEY72016.1 - 1.1e-17 63.6 1.4 5.1e-06 26.6 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KEY72016.1 - 2.5e-17 62.2 0.9 3.2e-06 26.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KEY72016.1 - 2.4e-15 56.1 5.5 0.00025 21.0 0.0 6.8 8 0 0 8 8 8 3 Kelch motif Kelch_3 PF13415.6 KEY72016.1 - 5.6e-14 52.0 14.1 4.4e-07 30.0 0.2 6.5 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KEY72016.1 - 8.5e-12 44.9 24.5 9.3e-06 25.6 0.1 8.1 7 2 1 8 8 8 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KEY72016.1 - 2.2e-10 40.1 3.6 7.8e-05 22.5 0.0 5.3 6 0 0 6 6 6 2 Kelch motif 2Fe-2S_thioredx PF01257.19 KEY72017.1 - 5.3e-57 191.8 0.0 6.6e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.28 KEY72018.1 - 3.4e-78 263.1 0.0 5e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY72018.1 - 1.3 10.0 5.4 0.92 10.5 0.8 3.0 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain DAO PF01266.24 KEY72019.1 - 7.9e-41 140.8 10.7 1e-40 140.4 10.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72019.1 - 0.0012 18.2 0.0 0.003 16.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY72019.1 - 0.0016 17.7 0.6 0.0026 17.1 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEY72019.1 - 0.0037 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KEY72019.1 - 0.004 17.4 0.1 0.01 16.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY72019.1 - 0.0062 15.7 3.3 0.0086 15.2 3.3 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEY72019.1 - 0.0071 15.6 0.2 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KEY72019.1 - 0.0099 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY72019.1 - 0.015 14.6 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY72019.1 - 0.038 12.7 1.3 0.061 12.0 0.9 1.5 2 0 0 2 2 2 0 HI0933-like protein Pkinase PF00069.25 KEY72020.1 - 4.6e-44 150.8 0.0 5.4e-42 144.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72020.1 - 4e-25 88.6 0.0 8.5e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 KEY72021.1 - 1e-25 89.5 1.0 1.6e-25 88.9 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY72021.1 - 1.1e-09 38.1 0.1 2.1e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KEY72021.1 - 0.0014 19.2 0.0 0.0075 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain CoaE PF01121.20 KEY72021.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_17 PF13207.6 KEY72021.1 - 0.23 11.9 0.0 0.98 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATG7_N PF16420.5 KEY72022.1 - 1.5e-107 359.7 0.0 1.9e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KEY72022.1 - 5.4e-43 147.1 0.0 8.6e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KEY72022.1 - 0.042 13.9 0.0 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pmp3 PF01679.17 KEY72023.1 - 1.3e-24 86.2 7.5 1.4e-24 86.0 7.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PIG-F PF06699.11 KEY72024.1 - 7.5e-60 202.2 2.3 9.5e-60 201.8 2.3 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.6 KEY72024.1 - 4.9 7.2 7.2 1.2 9.2 3.1 2.0 2 0 0 2 2 2 0 Glycine zipper MFS_1 PF07690.16 KEY72026.1 - 7.9e-33 113.8 26.5 7.9e-33 113.8 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KEY72026.1 - 2.2 8.1 22.3 0.11 12.3 13.6 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SNF2_N PF00176.23 KEY72027.1 - 6.3e-48 163.3 0.1 1.1e-47 162.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KEY72027.1 - 1.7e-24 85.7 0.7 1.7e-24 85.7 0.7 2.5 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KEY72027.1 - 8.1e-20 71.2 0.0 7.4e-19 68.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEY72027.1 - 1.8e-07 30.7 0.0 5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEY72027.1 - 5.9e-06 26.4 0.1 2.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEY72027.1 - 0.0012 18.7 0.0 0.004 17.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase IF2_assoc PF08364.11 KEY72027.1 - 0.067 13.5 0.9 0.39 11.0 0.6 2.4 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region AAA_34 PF13872.6 KEY72027.1 - 0.074 11.9 1.8 0.9 8.4 1.8 2.2 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 S4 PF01479.25 KEY72028.1 - 1.2e-11 44.1 0.1 3.6e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KEY72028.1 - 8.5e-10 39.4 1.3 1.4e-09 38.7 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain RED_C PF07807.11 KEY72028.1 - 0.056 13.9 0.1 0.091 13.2 0.1 1.3 1 0 0 1 1 1 0 RED-like protein C-terminal region Ribosomal_S18 PF01084.20 KEY72029.1 - 5.6e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.6 KEY72030.1 - 2.1e-06 27.7 0.0 0.0037 17.3 0.0 4.8 5 1 1 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KEY72030.1 - 3.1e-06 27.3 0.1 8.1 6.7 0.0 5.4 5 1 1 6 6 6 3 PPR repeat family PPR_long PF17177.4 KEY72030.1 - 0.001 18.5 0.2 0.054 12.8 0.1 2.5 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEY72030.1 - 0.0045 17.1 1.8 38 4.8 0.0 5.5 6 0 0 6 6 6 0 PPR repeat TPR_14 PF13428.6 KEY72030.1 - 0.013 16.3 0.7 0.12 13.2 0.7 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KEY72031.1 - 7.4e-47 160.0 0.0 3.1e-33 115.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family EamA PF00892.20 KEY72032.1 - 2.4e-09 37.5 29.0 6.1e-06 26.5 2.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family F-box-like PF12937.7 KEY72033.1 - 1.9e-06 27.7 12.8 2.4e-06 27.4 3.4 4.4 4 1 0 4 4 4 1 F-box-like F-box PF00646.33 KEY72033.1 - 0.02 14.8 9.5 0.76 9.7 0.0 4.0 3 1 0 3 3 3 0 F-box domain Methyltransf_2 PF00891.18 KEY72034.1 - 1.9e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KEY72034.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KEY72034.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KEY72034.1 - 0.036 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_2 PF00891.18 KEY72036.1 - 5.4e-26 91.2 0.0 8.3e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Sigma70_r4 PF04545.16 KEY72036.1 - 0.00099 18.6 0.0 0.0037 16.8 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Methyltransf_25 PF13649.6 KEY72036.1 - 0.0014 19.3 0.0 0.025 15.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain HTH_Tnp_ISL3 PF13542.6 KEY72036.1 - 0.0028 17.0 0.0 0.0063 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 KEY72036.1 - 0.0037 17.0 0.7 0.0079 16.0 0.2 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KEY72036.1 - 0.014 15.2 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KEY72036.1 - 0.017 15.3 0.2 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KEY72036.1 - 0.029 14.2 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KEY72036.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CheR PF01739.18 KEY72036.1 - 0.1 12.1 0.0 1.3 8.5 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain HTH_36 PF13730.6 KEY72036.1 - 0.16 12.0 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KEY72036.1 - 0.23 11.4 1.0 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 MarR family p450 PF00067.22 KEY72037.1 - 3.4e-26 92.0 0.0 4.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AbrB PF05145.12 KEY72037.1 - 0.046 12.7 0.1 0.08 11.9 0.1 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB AMP-binding PF00501.28 KEY72038.1 - 1.6e-57 195.0 0.0 3.4e-57 193.9 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Thioesterase PF00975.20 KEY72038.1 - 3e-26 93.0 0.1 1.4e-25 90.7 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KEY72038.1 - 6.3e-10 39.3 0.2 1.6e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 KEY72038.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY72038.1 - 0.0058 17.3 0.1 0.015 15.9 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72038.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GH3 PF03321.13 KEY72038.1 - 0.26 10.1 0.0 2 7.2 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Cerato-platanin PF07249.12 KEY72040.1 - 6.3e-56 187.6 0.6 7.3e-56 187.4 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin RHS_repeat PF05593.14 KEY72040.1 - 0.019 15.5 0.8 0.032 14.7 0.1 1.8 2 0 0 2 2 2 0 RHS Repeat Coiled PF05710.12 KEY72040.1 - 2.7 8.9 5.6 2.3 9.1 1.4 2.1 1 1 1 2 2 2 0 Coiled coil GHMP_kinases_N PF00288.26 KEY72041.1 - 2e-10 40.8 0.0 4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEY72041.1 - 3e-06 27.5 0.0 6.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Swi5 PF07061.11 KEY72041.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Swi5 4HBT_2 PF13279.6 KEY72042.1 - 8.9e-06 26.2 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.11 KEY72043.1 - 8e-10 38.7 8.5 1.3e-09 38.0 8.5 1.3 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 KEY72044.1 - 2.5e-14 53.4 19.2 0.001 19.8 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72044.1 - 5e-05 23.5 0.0 0.025 14.9 0.0 4.3 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY72044.1 - 0.00083 18.4 0.5 3.8 6.4 0.0 3.8 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY72044.1 - 0.0027 17.1 0.0 0.0079 15.6 0.0 1.8 1 1 1 2 2 2 2 WD40-like domain Glyco_transf_8 PF01501.20 KEY72046.1 - 1.2e-10 41.4 0.0 5.5e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 ATG2_CAD PF13329.6 KEY72047.1 - 5e-53 179.0 0.4 1e-52 177.9 0.4 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KEY72047.1 - 4.2e-28 97.5 0.1 4.3e-26 91.1 0.0 3.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 KEY72047.1 - 0.00014 21.7 0.0 0.00043 20.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KEY72047.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 KEY72048.1 - 1.6e-54 185.9 0.0 2.2e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY72048.1 - 5.9e-15 55.2 0.1 1.2e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY72048.1 - 1.2e-06 29.0 0.8 1e-05 26.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY72048.1 - 1.4e-06 27.7 0.3 3.4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY72048.1 - 2.2e-06 27.5 0.1 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY72048.1 - 9e-06 25.0 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY72048.1 - 0.00026 19.8 0.4 0.00042 19.1 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KEY72048.1 - 0.0022 18.0 0.2 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KEY72048.1 - 0.0027 17.0 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Prenylcys_lyase PF07156.14 KEY72048.1 - 0.0033 16.6 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase FAD_binding_3 PF01494.19 KEY72048.1 - 0.006 15.9 0.2 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KEY72048.1 - 0.0065 16.4 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY72048.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEY72048.1 - 0.044 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEY72048.1 - 0.048 13.0 0.0 0.091 12.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEY72048.1 - 0.068 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KEY72048.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEY72048.1 - 0.29 10.4 1.6 0.25 10.6 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyl-CoA_dh_1 PF00441.24 KEY72049.1 - 8e-27 94.3 0.4 1.4e-26 93.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KEY72049.1 - 2.1e-21 75.8 0.0 5.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KEY72049.1 - 9e-17 61.1 0.8 1.8e-16 60.1 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEY72049.1 - 9.3e-08 32.7 0.1 2.4e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEY72049.1 - 6e-07 29.8 0.1 1.1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.23 KEY72050.1 - 1.1e-55 183.4 69.8 3.2e-09 36.4 2.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KEY72050.1 - 3.1e-12 46.0 41.3 0.0042 16.8 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KEY72050.1 - 2.4e-09 37.0 53.5 0.071 13.1 0.5 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 KEY72050.1 - 1.4e-06 28.0 51.4 0.051 13.4 2.2 7.0 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KEY72050.1 - 0.0008 19.1 44.1 0.28 10.9 1.8 7.1 5 2 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KEY72050.1 - 0.0035 17.1 1.5 0.0035 17.1 1.5 6.8 7 0 0 7 7 7 3 Zinc knuckle SAE2 PF08573.10 KEY72051.1 - 9.1e-36 123.4 0.2 9.1e-36 123.4 0.2 3.2 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DNA_repr_REX1B PF14966.6 KEY72051.1 - 0.068 13.8 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 DNA repair REX1-B UCH PF00443.29 KEY72052.1 - 2.6e-48 164.8 0.0 4.2e-48 164.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY72052.1 - 1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCR_14kD PF02271.16 KEY72053.1 - 8.1e-42 141.3 0.9 9.3e-42 141.1 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 KEY72054.1 - 4.7e-64 212.4 2.4 1.3e-20 73.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipase_3 PF01764.25 KEY72054.1 - 0.09 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) AhpC-TSA PF00578.21 KEY72055.1 - 3.4e-22 78.7 0.0 5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEY72055.1 - 3.2e-13 49.6 0.0 4.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KEY72055.1 - 0.0043 17.1 0.0 0.013 15.7 0.0 1.7 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme Spore_coat_CotO PF14153.6 KEY72055.1 - 1.3 8.9 8.5 2.1 8.2 8.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3306 PF11748.8 KEY72055.1 - 1.4 9.8 8.2 2.7 8.9 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SasG_E PF17041.5 KEY72056.1 - 0.029 14.4 0.2 0.063 13.3 0.2 1.5 1 0 0 1 1 1 0 E domain CI-B14_5a PF07347.12 KEY72056.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DmpG_comm PF07836.11 KEY72056.1 - 0.1 12.1 0.2 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 DmpG-like communication domain DUF4837 PF16125.5 KEY72056.1 - 0.2 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Yae1_N PF09811.9 KEY72057.1 - 1.8e-09 37.1 6.0 2.8e-09 36.5 6.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Acetyltransf_1 PF00583.25 KEY72058.1 - 8.2e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY72058.1 - 1.6e-07 31.3 0.1 2.8e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY72058.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KEY72058.1 - 1.8e-05 25.0 0.0 3.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY72058.1 - 0.012 15.7 0.2 0.028 14.5 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.6 KEY72059.1 - 0.1 13.2 0.0 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) DUF4407 PF14362.6 KEY72059.1 - 7.2 5.9 11.2 2.1 7.6 2.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) IF-2B PF01008.17 KEY72060.1 - 4.6e-46 157.3 0.1 1.2e-45 155.9 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.18 KEY72061.1 - 6.4e-56 188.4 0.0 8.8e-56 188.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4603 PF15376.6 KEY72061.1 - 0.09 10.2 7.0 0.12 9.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1761 PF08570.10 KEY72062.1 - 1.3e-23 83.6 3.4 1.5e-23 83.4 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) BRCT_assoc PF12820.7 KEY72062.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Ribosomal_L7Ae PF01248.26 KEY72063.1 - 1.1e-22 79.5 0.4 4.7e-22 77.5 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4050 PF13259.6 KEY72063.1 - 5 7.4 9.2 1.2 9.5 5.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) AF-4 PF05110.13 KEY72063.1 - 7.8 4.4 20.3 12 3.9 20.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UcrQ PF02939.16 KEY72064.1 - 3.7e-36 122.9 1.0 4.6e-36 122.6 1.0 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 KEY72065.1 - 3.3e-23 82.6 8.6 6.6e-23 81.6 8.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KEY72065.1 - 0.00031 19.9 5.6 0.00041 19.5 5.6 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Nucleocap_ssRNA PF11128.8 KEY72066.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid DUF676 PF05057.14 KEY72067.1 - 2e-50 171.4 0.0 2.8e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY72067.1 - 0.0013 19.4 0.2 0.0096 16.5 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KEY72067.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KEY72067.1 - 0.0018 18.0 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein PRELI PF04707.14 KEY72068.1 - 2e-20 73.2 0.1 1.9e-17 63.5 0.1 2.6 1 1 1 2 2 2 2 PRELI-like family Pkinase PF00069.25 KEY72069.1 - 1.1e-10 41.3 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72069.1 - 3.8e-07 29.7 0.0 7.2e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY72069.1 - 0.039 12.7 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LMWPc PF01451.21 KEY72070.1 - 1.2e-41 142.4 0.0 1.4e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 KEY72071.1 - 9.4e-65 218.6 0.0 1.3e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72071.1 - 9.3e-28 97.2 0.0 2.8e-27 95.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY72071.1 - 0.077 12.9 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEY72071.1 - 0.086 12.2 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3455 PF11937.8 KEY72072.1 - 3.3e-27 95.8 0.0 4.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Hexapep PF00132.24 KEY72073.1 - 1.7e-11 43.4 5.8 2.6e-05 23.8 2.4 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEY72073.1 - 1.6e-05 24.5 4.6 0.00011 21.9 2.6 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KEY72073.1 - 0.003 16.6 0.1 0.0052 15.8 0.1 1.3 1 1 0 1 1 1 1 L-fucokinase Apolipoprotein PF01442.18 KEY72074.1 - 2.7e-05 24.1 17.2 0.0014 18.5 13.8 3.0 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Globin PF00042.22 KEY72074.1 - 0.025 15.1 4.0 0.36 11.4 0.0 3.6 2 1 1 3 3 3 0 Globin CorA PF01544.18 KEY72074.1 - 0.029 13.7 1.2 0.17 11.2 0.0 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein FAM104 PF15434.6 KEY72074.1 - 0.054 14.1 0.5 0.22 12.1 0.2 2.1 2 0 0 2 2 2 0 Family 104 Arg_decarb_HB PF17810.1 KEY72074.1 - 0.087 13.1 0.7 0.5 10.7 0.2 2.5 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain Phasin_2 PF09361.10 KEY72074.1 - 0.12 12.6 17.2 1.5 9.2 0.0 5.0 4 1 2 6 6 6 0 Phasin protein DUF2937 PF11157.8 KEY72074.1 - 1.2 8.9 4.2 22 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) DUF948 PF06103.11 KEY72074.1 - 1.2 9.5 10.7 17 5.8 0.6 4.8 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 KEY72074.1 - 1.3 9.1 24.9 1.7 8.8 2.9 4.9 3 1 2 5 5 5 0 Apolipophorin-III precursor (apoLp-III) FAM184 PF15665.5 KEY72074.1 - 1.4 8.7 22.7 0.55 10.0 4.1 4.0 2 1 0 3 3 3 0 Family with sequence similarity 184, A and B REF PF05755.12 KEY72074.1 - 7.3 6.4 9.8 10 5.9 0.2 3.5 2 1 2 4 4 4 0 Rubber elongation factor protein (REF) MT0933_antitox PF14013.6 KEY72074.1 - 9.1 6.7 34.8 1.9 8.8 7.3 5.8 3 1 1 4 4 4 0 MT0933-like antitoxin protein WXG100 PF06013.12 KEY72074.1 - 9.1 6.6 8.7 5.9 7.2 0.9 3.8 3 1 2 5 5 5 0 Proteins of 100 residues with WXG CSTF2_hinge PF14327.6 KEY72074.1 - 9.4 6.8 6.7 12 6.4 0.2 4.0 4 1 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 PRELI PF04707.14 KEY72075.1 - 6.9e-43 146.2 0.1 8.7e-43 145.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family AATase PF07247.12 KEY72076.1 - 3.1e-09 35.9 0.0 1.9e-08 33.3 0.0 2.1 3 0 0 3 3 3 1 Alcohol acetyltransferase Condensation PF00668.20 KEY72076.1 - 0.00066 18.5 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AA_permease PF00324.21 KEY72077.1 - 5.3e-118 394.6 39.7 6.4e-118 394.4 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY72077.1 - 8.8e-37 126.9 43.5 1.1e-36 126.6 43.5 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.24 KEY72078.1 - 1.3e-44 152.5 0.1 1.6e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KEY72078.1 - 0.11 12.4 1.1 0.47 10.4 1.4 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 PRK PF00485.18 KEY72079.1 - 2.3e-05 24.2 0.0 3.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KEY72079.1 - 5.3e-05 23.8 0.7 0.00073 20.1 0.7 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEY72079.1 - 0.0004 19.7 0.5 0.0033 16.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 KEY72079.1 - 0.00087 19.7 0.0 0.75 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KEY72079.1 - 0.00096 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KEY72079.1 - 0.0034 17.6 2.3 0.084 13.0 2.3 2.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KEY72079.1 - 0.0051 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KEY72079.1 - 0.035 13.8 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 KEY72079.1 - 0.039 13.6 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 KEY72079.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEY72079.1 - 0.096 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KEY72079.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KEY72079.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.19 KEY72079.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KEY72079.1 - 0.22 10.7 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AhpC-TSA_2 PF13911.6 KEY72080.1 - 1.4e-17 63.8 0.0 4e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KEY72080.1 - 0.00035 20.5 0.0 0.00089 19.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEY72080.1 - 0.00053 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin F-box PF00646.33 KEY72083.1 - 0.00079 19.2 0.1 0.0022 17.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY72083.1 - 0.0027 17.5 0.1 0.0027 17.5 0.1 2.2 3 0 0 3 3 3 1 F-box-like Chitin_synth_1 PF01644.17 KEY72084.1 - 1.9e-73 245.8 0.3 2.9e-73 245.2 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEY72084.1 - 3.8e-28 97.2 0.1 9.1e-28 96.0 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEY72084.1 - 5.1e-24 84.8 0.9 1.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEY72084.1 - 1.3e-05 25.2 9.3 1.3e-05 25.2 9.3 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Pro-kuma_activ PF09286.11 KEY72085.1 - 6.5e-21 75.1 0.0 2e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KEY72085.1 - 2.4e-08 33.6 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Translin PF01997.16 KEY72086.1 - 2.6e-49 168.0 0.0 3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Translin family zf-CCCH_4 PF18044.1 KEY72087.1 - 8e-08 31.9 2.4 1.3e-07 31.3 2.4 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEY72087.1 - 3.4e-06 26.9 5.8 5.9e-06 26.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KEY72087.1 - 0.00012 21.9 2.6 0.00025 20.9 2.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KEY72087.1 - 0.0027 17.9 0.4 0.0027 17.9 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEY72087.1 - 0.051 14.1 1.5 0.1 13.1 1.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KEY72087.1 - 0.074 13.7 0.2 0.074 13.7 0.2 2.2 2 0 0 2 2 2 0 Torus domain DUF5521 PF17659.1 KEY72087.1 - 0.29 8.9 1.3 0.54 8.0 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Sec1 PF00995.23 KEY72088.1 - 4.2e-129 432.4 0.0 4.8e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ino80_Iec3 PF14612.6 KEY72089.1 - 4.5e-52 178.1 2.7 1.3e-30 107.8 0.6 2.3 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 KEY72090.1 - 2.3e-71 240.8 0.0 2.7e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short_C2 PF13561.6 KEY72091.1 - 3.6e-52 177.3 0.1 3.6e-52 177.3 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY72091.1 - 3.8e-45 153.8 1.4 8.6e-45 152.6 0.0 2.3 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.10 KEY72091.1 - 1.8e-11 44.2 0.1 1.8e-11 44.2 0.1 2.2 2 0 0 2 2 2 1 KR domain TSC22 PF01166.18 KEY72091.1 - 3.3e-05 24.1 16.7 0.0082 16.4 0.1 5.2 4 1 1 5 5 5 2 TSC-22/dip/bun family DUF1776 PF08643.10 KEY72091.1 - 0.0029 17.0 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Filament PF00038.21 KEY72091.1 - 0.0044 16.7 17.1 0.0044 16.7 17.1 5.2 4 1 2 6 6 6 1 Intermediate filament protein Epimerase PF01370.21 KEY72091.1 - 0.006 16.1 0.2 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KEY72091.1 - 0.055 13.4 0.0 0.055 13.4 0.0 4.5 4 1 1 5 5 5 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIT_CC PF16559.5 KEY72091.1 - 0.056 13.3 22.1 0.14 12.1 1.9 4.9 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor GDP_Man_Dehyd PF16363.5 KEY72091.1 - 0.14 11.6 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FlaC_arch PF05377.11 KEY72091.1 - 0.19 12.1 41.8 0.45 11.0 0.4 7.7 7 1 1 8 8 7 0 Flagella accessory protein C (FlaC) Hemagglutinin PF00509.18 KEY72091.1 - 0.24 9.8 4.5 0.45 8.8 4.5 1.4 1 0 0 1 1 1 0 Haemagglutinin FtsK_alpha PF17854.1 KEY72091.1 - 0.65 10.2 3.7 1.8 8.8 0.0 3.7 5 1 0 5 5 3 0 FtsK alpha domain NumbF PF06311.12 KEY72091.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.6 3 1 0 3 3 3 0 NUMB domain ATG16 PF08614.11 KEY72091.1 - 1.4 9.1 71.7 0.036 14.3 19.9 4.7 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KEY72091.1 - 3 7.6 47.9 7.9 6.3 18.0 5.0 1 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH FOXP-CC PF16159.5 KEY72093.1 - 0.0022 18.6 2.6 1.2 9.8 0.1 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain Salp15 PF12115.8 KEY72093.1 - 0.19 12.2 7.3 0.42 11.1 7.1 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation zf-C3HC4 PF00097.25 KEY72093.1 - 9.3 6.2 10.7 0.72 9.8 4.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Not3 PF04065.15 KEY72094.1 - 5.3e-89 297.6 25.7 1.1e-88 296.6 25.7 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KEY72094.1 - 4.5e-44 149.7 7.7 1.3e-43 148.2 7.7 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ABC_tran_CTD PF16326.5 KEY72094.1 - 0.018 15.3 6.1 0.018 15.3 6.1 3.7 1 1 2 3 3 2 0 ABC transporter C-terminal domain DUF2373 PF10180.9 KEY72094.1 - 0.024 14.5 3.7 0.059 13.2 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 KEY72094.1 - 0.25 11.4 9.0 0.033 14.3 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Sec5 PF15469.6 KEY72094.1 - 0.62 9.8 12.1 0.21 11.4 3.7 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.13 KEY72094.1 - 0.9 10.0 10.2 1.4 9.4 3.6 3.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.8 KEY72094.1 - 1.1 8.5 21.5 0.86 8.9 8.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 KEY72094.1 - 1.1 9.8 4.4 2.1 8.9 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 KEY72094.1 - 1.9 8.9 14.5 0.16 12.3 6.8 2.9 3 0 0 3 3 3 0 Syntaxin-like protein PI3K_P85_iSH2 PF16454.5 KEY72094.1 - 2.6 7.6 22.8 0.2 11.3 5.5 2.9 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 KEY72094.1 - 3.7 7.5 14.5 0.12 12.3 2.6 3.2 2 1 1 3 3 3 0 Prefoldin subunit LPP PF04728.13 KEY72094.1 - 4.3 7.8 14.5 0.083 13.3 1.4 3.9 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Tyr_Deacylase PF02580.16 KEY72095.1 - 4.3e-43 147.3 0.0 6.5e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KEY72096.1 - 7.3e-49 166.1 0.1 1.2e-48 165.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KEY72096.1 - 4e-05 23.4 6.8 0.00033 20.5 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY72096.1 - 0.011 15.8 3.6 0.021 15.0 3.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY72096.1 - 0.025 14.4 0.2 0.025 14.4 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY72096.1 - 0.044 14.6 5.0 0.12 13.2 1.5 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 KEY72097.1 - 1.6e-27 96.6 0.0 8.5e-20 71.3 0.0 2.6 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KEY72097.1 - 4.4e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain MRP-L20 PF12824.7 KEY72099.1 - 6e-49 166.4 5.2 6.9e-49 166.2 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KEY72099.1 - 7.2e-05 22.9 0.3 0.00019 21.5 0.2 1.8 2 0 0 2 2 2 1 Neugrin CBM_20 PF00686.19 KEY72100.1 - 1.7e-32 111.2 1.4 3.2e-32 110.3 1.4 1.5 1 0 0 1 1 1 1 Starch binding domain Cu-oxidase_4 PF02578.15 KEY72103.1 - 4.3e-28 98.5 0.0 6.1e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Pectinesterase PF01095.19 KEY72105.1 - 8.1e-45 152.8 3.0 1.1e-44 152.4 3.0 1.1 1 0 0 1 1 1 1 Pectinesterase Zn_clus PF00172.18 KEY72106.1 - 2.5e-09 37.1 8.5 4.4e-09 36.3 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY72106.1 - 0.00013 20.9 0.1 0.00018 20.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ilm1 PF10311.9 KEY72106.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 RTA1 PF04479.13 KEY72107.1 - 8.8e-68 228.0 8.7 1.1e-67 227.6 8.7 1.1 1 0 0 1 1 1 1 RTA1 like protein LHC PF00556.20 KEY72107.1 - 6 7.2 7.2 5.5 7.3 1.0 2.8 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit PalH PF08733.10 KEY72107.1 - 6.2 5.7 11.9 1.3 8.0 7.7 1.9 2 1 0 2 2 2 0 PalH/RIM21 Ank_2 PF12796.7 KEY72110.1 - 1.7e-12 47.8 0.0 1.6e-06 28.6 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY72110.1 - 3.9e-12 46.1 0.2 9.6e-06 25.8 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY72110.1 - 2.4e-10 40.4 0.0 0.0088 16.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEY72110.1 - 2.7e-06 27.3 0.0 1.6 9.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KEY72110.1 - 4.2e-06 27.2 0.1 0.0078 16.8 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) vWA-TerF-like PF10138.9 KEY72110.1 - 0.00055 20.1 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 KEY72110.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain MHC2-interact PF09307.10 KEY72110.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting Fungal_trans PF04082.18 KEY72111.1 - 3.2e-09 36.2 0.3 8.7e-09 34.8 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72111.1 - 0.0082 16.2 16.4 0.0082 16.2 16.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_q6 PF01058.22 KEY72112.1 - 5.6e-22 78.0 0.1 8.6e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 KEY72112.1 - 0.16 12.3 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Dec-1 protein, C terminal region DUF4064 PF13273.6 KEY72113.1 - 0.086 13.1 1.2 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) MARVEL PF01284.23 KEY72113.1 - 0.16 12.0 8.1 0.26 11.3 8.1 1.4 1 1 0 1 1 1 0 Membrane-associating domain Reticulon PF02453.17 KEY72114.1 - 2.9e-17 63.1 0.0 6.4e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Reticulon ATP-synt_B PF00430.18 KEY72114.1 - 0.016 15.3 9.4 0.016 15.3 9.4 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) REF PF05755.12 KEY72114.1 - 1.5 8.6 4.2 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) CDH-cyt PF16010.5 KEY72115.1 - 4.3e-46 156.9 0.0 5.7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Peptidase_M64 PF09471.10 KEY72116.1 - 4.5e-21 75.6 0.2 3.8e-17 62.7 0.0 3.2 2 2 0 2 2 2 2 IgA Peptidase M64 UnbV_ASPIC PF07593.12 KEY72117.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 ASPIC and UnbV HAD_2 PF13419.6 KEY72118.1 - 2.1e-16 60.5 0.0 4.2e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Sulfotransfer_3 PF13469.6 KEY72118.1 - 5.9e-08 33.4 0.1 0.00069 20.1 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase family Hydrolase PF00702.26 KEY72118.1 - 0.00027 21.3 0.2 0.0018 18.6 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY72118.1 - 0.0032 17.5 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Sulfotransfer_1 PF00685.27 KEY72118.1 - 0.0053 16.3 0.0 1.1 8.7 0.0 2.7 1 1 0 1 1 1 1 Sulfotransferase domain HAD PF12710.7 KEY72118.1 - 0.015 15.7 0.2 0.027 14.9 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEY72118.1 - 0.15 11.8 0.0 0.84 9.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1996 PF09362.10 KEY72119.1 - 2e-77 260.3 1.5 2e-77 260.3 1.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Pkinase PF00069.25 KEY72120.1 - 3.6e-34 118.3 0.0 9.1e-34 117.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72120.1 - 4.2e-11 42.6 0.0 0.00023 20.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KEY72120.1 - 0.0066 15.5 0.3 0.01 14.9 0.3 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FPN1 PF06963.12 KEY72121.1 - 3.2e-104 348.9 23.9 9.4e-104 347.4 23.9 1.6 1 1 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.7 KEY72121.1 - 0.0058 15.5 2.2 0.01 14.8 2.2 1.6 1 1 0 1 1 1 1 MFS_1 like family BATS PF06968.13 KEY72123.1 - 3.9e-23 81.4 0.0 1.4e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KEY72123.1 - 3.3e-16 60.1 0.1 8.3e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily MFS_1 PF07690.16 KEY72125.1 - 5e-35 121.1 33.1 7.3e-35 120.5 33.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72125.1 - 1e-06 27.9 12.8 1.4e-06 27.5 12.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 KEY72125.1 - 1 9.1 8.4 0.1 12.3 2.6 2.2 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 BRI3BP PF14965.6 KEY72125.1 - 2.9 7.4 6.3 1.2 8.6 2.4 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 zf-C2H2 PF00096.26 KEY72126.1 - 4.3e-07 30.0 13.8 0.072 13.6 2.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KEY72126.1 - 0.0055 16.9 0.1 0.18 11.9 0.0 2.2 1 1 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KEY72126.1 - 0.026 15.4 11.6 3.9 8.6 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Leu_zip PF15294.6 KEY72126.1 - 0.027 14.0 1.1 0.043 13.3 1.1 1.2 1 0 0 1 1 1 0 Leucine zipper ZapB PF06005.12 KEY72126.1 - 0.034 14.6 1.7 0.076 13.5 1.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB HalX PF08663.10 KEY72126.1 - 0.069 13.5 6.0 0.13 12.6 5.5 1.8 1 1 0 1 1 1 0 HalX domain DivIC PF04977.15 KEY72126.1 - 0.23 11.2 1.9 0.49 10.2 1.4 1.9 2 0 0 2 2 2 0 Septum formation initiator zf-H2C2_2 PF13465.6 KEY72126.1 - 5.8 7.5 20.3 6.8 7.3 0.7 4.3 4 1 0 4 4 4 0 Zinc-finger double domain FCH PF00611.23 KEY72127.1 - 1.1e-25 89.7 0.4 1.1e-25 89.7 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KEY72127.1 - 2.9e-18 65.5 0.7 3.2e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KEY72127.1 - 5.9e-15 54.9 5.2 9.5e-15 54.2 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KEY72127.1 - 6.4e-13 48.1 0.1 3.4e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KEY72127.1 - 4.3e-05 23.7 1.1 0.011 16.0 0.2 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_2 PF07653.17 KEY72127.1 - 0.0027 17.3 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain C1_2 PF03107.16 KEY72127.1 - 0.0069 16.7 4.4 0.012 15.9 4.4 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 KEY72127.1 - 0.032 14.3 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 SH3 domain Allexi_40kDa PF05549.11 KEY72127.1 - 0.068 12.7 1.5 0.3 10.6 0.0 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein FYVE PF01363.21 KEY72127.1 - 0.16 12.1 3.1 0.36 11.0 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger V-ATPase_G_2 PF16999.5 KEY72127.1 - 9.7 6.7 9.3 4.4 7.8 3.8 2.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AMP-binding PF00501.28 KEY72128.1 - 5.8e-92 308.5 0.0 6.8e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY72128.1 - 5.9e-16 59.2 0.1 1.6e-15 57.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KEY72128.1 - 5.8e-05 22.1 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KEY72128.1 - 0.013 15.6 0.1 0.048 13.7 0.0 2.0 1 1 1 2 2 2 0 RTX C-terminal domain FKBP26_C PF18046.1 KEY72128.1 - 0.054 13.6 1.0 1.6 8.9 0.7 2.5 2 0 0 2 2 2 0 FKBP26_C-terminal SLAC1 PF03595.17 KEY72131.1 - 5e-81 272.5 45.1 5.8e-81 272.2 45.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Spo7 PF03907.13 KEY72131.1 - 0.02 14.4 0.3 0.02 14.4 0.3 1.8 2 1 1 3 3 3 0 Spo7-like protein DUF3099 PF11298.8 KEY72131.1 - 6.4 7.0 8.8 15 5.8 4.7 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) YCII PF03795.14 KEY72132.1 - 1.5e-09 38.1 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2408 PF10303.9 KEY72133.1 - 3.2e-40 137.8 9.7 2.6e-26 92.8 0.5 4.9 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) Cob_adeno_trans PF01923.18 KEY72133.1 - 0.039 14.1 1.8 0.22 11.6 0.3 2.6 2 1 0 3 3 3 0 Cobalamin adenosyltransferase FUSC PF04632.12 KEY72133.1 - 0.21 10.1 1.8 0.58 8.6 0.5 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1539 PF07560.11 KEY72133.1 - 0.99 9.5 3.9 1.3 9.2 0.4 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF4201 PF13870.6 KEY72133.1 - 3.6 7.3 12.6 0.17 11.6 1.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4201) Ribosomal_60s PF00428.19 KEY72134.1 - 1.3e-26 93.0 10.5 1.6e-26 92.7 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KEY72134.1 - 0.52 8.7 1.1 0.65 8.4 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein UBX PF00789.20 KEY72135.1 - 2.4e-08 34.1 0.4 7.1e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KEY72135.1 - 1.6e-05 24.7 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.26 KEY72135.1 - 0.2 12.2 0.1 0.4 11.2 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.6 KEY72135.1 - 0.84 10.2 9.4 1 9.9 9.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Vps39_2 PF10367.9 KEY72135.1 - 2.7 8.5 0.0 2.7 8.5 0.0 2.8 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2HE PF16278.5 KEY72135.1 - 9.1 6.8 9.7 0.4 11.2 0.3 3.0 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Motile_Sperm PF00635.26 KEY72136.1 - 7.8e-25 86.9 0.5 1.9e-24 85.6 0.2 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KEY72136.1 - 0.0043 17.2 0.8 0.12 12.6 0.0 2.6 2 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF756 PF05506.12 KEY72136.1 - 0.045 14.7 0.0 0.13 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF756) DUF5001 PF16392.5 KEY72136.1 - 0.06 13.3 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 Ig-like domain fn3_6 PF17766.1 KEY72136.1 - 1.3 9.2 4.9 0.69 10.1 1.3 2.5 2 1 1 3 3 3 0 Fibronectin type-III domain Aa_trans PF01490.18 KEY72137.1 - 2.6e-25 89.0 32.3 4.1e-25 88.3 32.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_desaturase PF00487.24 KEY72137.1 - 4.1e-24 85.8 16.4 4.1e-24 85.8 16.4 5.6 2 2 2 5 5 5 3 Fatty acid desaturase Lipid_DES PF08557.10 KEY72137.1 - 1.9e-19 68.9 0.3 5.6e-19 67.3 0.2 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) ICE2 PF08426.10 KEY72138.1 - 4.5e-151 503.6 14.2 5.2e-151 503.4 14.2 1.0 1 0 0 1 1 1 1 ICE2 Peptidase_S9 PF00326.21 KEY72139.1 - 0.0028 17.2 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KEY72139.1 - 0.2 10.3 0.1 0.27 9.9 0.1 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF218 PF02698.17 KEY72140.1 - 3.1e-10 40.2 0.0 4.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain DUF4007 PF13182.6 KEY72140.1 - 0.24 10.5 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Mur_ligase_M PF08245.12 KEY72141.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain DUF4404 PF14357.6 KEY72141.1 - 0.37 11.5 4.8 0.14 12.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 KEY72143.1 - 1.9e-71 240.6 0.0 3.8e-71 239.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72143.1 - 2.1e-49 168.1 0.0 3.4e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEY72143.1 - 0.00019 20.4 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEY72143.1 - 0.044 13.1 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RTTN_N PF14726.6 KEY72143.1 - 0.21 12.4 1.8 10 7.0 0.4 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DUF1685 PF07939.11 KEY72144.1 - 0.093 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Ank_2 PF12796.7 KEY72147.1 - 1.2e-13 51.4 0.1 5.9e-06 26.8 0.6 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEY72147.1 - 2.9e-11 43.3 0.5 0.00074 19.9 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KEY72147.1 - 3.5e-11 43.4 2.2 0.00044 20.8 0.3 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY72147.1 - 1.8e-08 33.9 0.1 0.43 11.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KEY72147.1 - 3.3e-07 30.4 2.4 0.00088 19.5 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KEY72147.1 - 2.8e-06 27.1 0.5 6.9e-05 22.7 0.5 2.9 2 1 0 2 2 2 1 KilA-N domain Actin PF00022.19 KEY72148.1 - 1.1e-125 419.5 0.0 4.8e-125 417.3 0.0 1.8 1 1 0 1 1 1 1 Actin DUF3602 PF12223.8 KEY72149.1 - 2e-18 66.7 5.6 2.4e-13 50.5 0.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) zf-MYND PF01753.18 KEY72150.1 - 0.00074 19.6 14.1 0.02 15.0 5.8 2.3 2 0 0 2 2 2 2 MYND finger Glyco_hydro_76 PF03663.14 KEY72151.1 - 7.2e-151 502.8 8.2 8.5e-151 502.6 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY72151.1 - 0.0068 15.5 9.7 0.22 10.5 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 COPIIcoated_ERV PF07970.12 KEY72152.1 - 1e-38 133.4 0.1 1.6e-38 132.7 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEY72152.1 - 3.5e-26 91.4 0.0 6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3824 PF12868.7 KEY72153.1 - 0.00019 22.1 29.0 0.00053 20.7 10.8 10.0 4 3 5 9 9 9 4 Domain of unknwon function (DUF3824) DUF533 PF04391.12 KEY72153.1 - 0.36 10.4 16.3 0.17 11.5 0.7 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF533) DnaJ PF00226.31 KEY72154.1 - 1.9e-26 91.9 2.4 3.2e-26 91.2 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KEY72154.1 - 3e-24 85.8 0.0 4.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KEY72154.1 - 3.8e-14 52.8 17.2 6.2e-14 52.1 17.2 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KEY72154.1 - 0.00014 21.9 7.3 0.081 12.9 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KEY72154.1 - 0.0006 19.7 8.6 0.11 12.5 2.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KEY72154.1 - 0.25 11.0 6.4 0.33 10.6 0.2 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 OB_NTP_bind PF07717.16 KEY72155.1 - 8.5e-22 77.3 0.0 2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEY72155.1 - 3.1e-17 62.8 0.0 3.1e-17 62.8 0.0 3.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEY72155.1 - 2e-14 53.9 0.0 6.2e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEY72155.1 - 1.6e-05 25.2 0.0 6.1e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KEY72155.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KEY72155.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEY72155.1 - 0.0025 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KEY72155.1 - 0.011 15.4 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KEY72155.1 - 0.025 14.9 0.1 0.057 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY72155.1 - 0.055 14.0 0.4 0.3 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 KEY72155.1 - 0.18 11.4 0.3 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain His_Phos_1 PF00300.22 KEY72156.1 - 5.3e-22 78.5 0.1 6.3e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chromate_transp PF02417.15 KEY72157.1 - 1.5e-56 190.9 38.6 4.6e-34 117.8 16.2 2.5 3 0 0 3 3 3 2 Chromate transporter Chon_Sulph_att PF06566.11 KEY72157.1 - 1.4 8.7 3.2 2.1 8.2 3.2 1.2 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain TMP_2 PF06791.13 KEY72157.1 - 1.4 8.5 5.6 0.64 9.7 1.3 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein HET PF06985.11 KEY72158.1 - 2.6e-29 102.5 0.0 5.1e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY72159.1 - 3.9e-37 126.7 0.1 6.4e-06 26.7 0.0 8.3 4 3 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY72159.1 - 2.9e-26 88.6 16.9 0.0098 16.3 0.0 12.9 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 KEY72159.1 - 5.7e-26 90.5 8.5 0.00074 20.0 0.1 9.5 8 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 KEY72159.1 - 1.8e-18 66.0 24.9 0.03 14.8 0.1 11.9 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 KEY72159.1 - 1.8e-14 53.6 23.3 0.027 14.8 0.1 10.3 8 4 4 12 12 12 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KEY72159.1 - 0.00023 21.0 0.1 0.00064 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KEY72159.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 F-box RVP PF00077.20 KEY72159.1 - 0.051 13.9 0.1 16 5.9 0.0 4.3 5 0 0 5 5 5 0 Retroviral aspartyl protease Ribosomal_S17e PF00833.18 KEY72160.1 - 3.5e-55 185.2 0.1 4e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Sugar_tr PF00083.24 KEY72161.1 - 5.1e-88 295.9 12.2 8.4e-88 295.2 12.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72161.1 - 1.8e-30 106.0 27.8 8.3e-30 103.9 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp_Glu_race PF01177.22 KEY72162.1 - 3.6e-06 27.0 0.0 1.1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.19 KEY72163.1 - 6.9e-106 354.3 0.0 4.1e-105 351.7 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEY72163.1 - 0.064 12.1 0.0 1.5 7.6 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein Actin_micro PF17003.5 KEY72163.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Putative actin-like family Pkinase PF00069.25 KEY72164.1 - 5e-61 206.4 0.0 6.6e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72164.1 - 9.3e-31 107.0 0.0 1.3e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY72164.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KEY72164.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Arf PF00025.21 KEY72165.1 - 1.8e-75 252.2 0.1 2e-75 252.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEY72165.1 - 1.4e-13 51.1 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEY72165.1 - 1.1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KEY72165.1 - 2.3e-12 46.8 0.0 2.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KEY72165.1 - 4.8e-12 45.7 2.1 3.6e-08 33.0 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KEY72165.1 - 7.9e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY72165.1 - 0.00034 20.7 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEY72165.1 - 0.028 13.7 0.3 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 KEY72165.1 - 0.045 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Methyltrn_RNA_3 PF02598.17 KEY72165.1 - 0.064 12.8 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase SpoOE-like PF09388.10 KEY72165.1 - 0.12 12.3 1.9 0.2 11.6 1.9 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein DUF1325 PF07039.11 KEY72166.1 - 2.3e-35 121.6 0.0 4e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Mucin PF01456.17 KEY72166.1 - 0.027 14.4 14.7 0.049 13.6 14.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 KEY72166.1 - 0.034 12.4 8.8 0.047 11.9 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 KEY72166.1 - 0.68 9.9 9.1 1.4 8.9 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MGC-24 PF05283.11 KEY72166.1 - 4.5 7.7 9.6 3.8 8.0 7.2 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PMI_typeI PF01238.21 KEY72167.1 - 5.4e-133 443.8 0.0 6.4e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Zn_clus PF00172.18 KEY72168.1 - 1.8e-08 34.3 7.6 2.8e-08 33.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KEY72170.1 - 1.9e-33 116.0 0.0 3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KEY72170.1 - 5.4e-15 55.0 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3659 PF12396.8 KEY72170.1 - 0.072 13.0 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Activator_LAG-3 PF11498.8 KEY72171.1 - 0.0013 17.8 0.2 0.0013 17.8 0.2 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Methyltransf_16 PF10294.9 KEY72172.1 - 7.7e-18 64.8 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KEY72172.1 - 0.00038 20.2 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KEY72172.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KEY72172.1 - 0.0034 18.0 0.0 0.0085 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY72172.1 - 0.0053 16.5 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KEY72172.1 - 0.0058 16.1 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KEY72172.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72172.1 - 0.074 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEY72172.1 - 0.087 13.6 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.19 KEY72173.1 - 8e-34 115.4 0.0 1.5e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Thrombin_light PF09396.10 KEY72174.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Thrombin light chain GTP_cyclohydro2 PF00925.20 KEY72176.1 - 1.2e-62 210.3 0.0 1.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Cerato-platanin PF07249.12 KEY72177.1 - 0.004 17.3 0.4 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 Cerato-platanin RPA43_OB PF17875.1 KEY72178.1 - 6.9e-34 117.1 0.1 6.9e-34 117.1 0.1 3.8 4 1 0 4 4 4 1 RPA43 OB domain in RNA Pol I FHA PF00498.26 KEY72179.1 - 4.2e-05 23.8 0.0 6.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEY72179.1 - 0.00015 22.0 0.0 0.00027 21.2 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NDUF_B7 PF05676.13 KEY72180.1 - 1.9e-29 101.1 6.5 2.2e-29 100.9 6.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KEY72180.1 - 0.00054 19.9 2.9 0.00083 19.3 2.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Galactosyl_T PF01762.21 KEY72183.1 - 2.2e-13 50.5 1.3 4.3e-12 46.3 1.3 2.1 1 1 0 1 1 1 1 Galactosyltransferase DUF1304 PF06993.12 KEY72184.1 - 2.2e-45 153.2 5.0 2.5e-45 153.0 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Recep_L_domain PF01030.24 KEY72185.1 - 1.3e-09 38.2 0.0 0.018 15.2 0.0 4.3 3 2 0 3 3 3 3 Receptor L domain SKG6 PF08693.10 KEY72185.1 - 0.00052 19.4 0.9 0.001 18.4 0.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain G_glu_transpept PF01019.21 KEY72186.1 - 8.9e-143 476.7 0.0 1e-142 476.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NMT1_2 PF13379.6 KEY72186.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family Glutaredoxin PF00462.24 KEY72187.1 - 8.6e-16 57.9 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GCN5L1 PF06320.13 KEY72188.1 - 0.095 12.9 3.7 0.056 13.6 0.9 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF3093 PF11292.8 KEY72188.1 - 0.15 12.4 0.9 0.96 9.7 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3093) YabA PF06156.13 KEY72188.1 - 0.21 12.2 1.7 2.9 8.6 0.1 3.0 3 0 0 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KEY72188.1 - 0.53 10.3 10.3 6.3 6.8 1.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 KEY72188.1 - 0.61 10.6 3.1 2 8.9 3.1 1.9 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 KEY72188.1 - 1 9.2 8.2 6.8 6.5 6.0 2.7 2 1 0 2 2 2 0 Septum formation initiator Golgin_A5 PF09787.9 KEY72188.1 - 1.7 8.1 11.9 0.2 11.1 1.0 2.4 3 0 0 3 3 3 0 Golgin subfamily A member 5 UPF0242 PF06785.11 KEY72188.1 - 3.1 7.9 9.2 0.78 9.8 1.4 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 KEY72188.1 - 6.6 7.2 9.3 17 5.9 0.4 2.7 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF1943 PF09172.11 KEY72189.1 - 2.2 7.4 6.7 3.6 6.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MYO10_CC PF16735.5 KEY72189.1 - 3.9 7.6 15.1 0.38 10.9 1.1 3.7 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain GerE PF00196.19 KEY72190.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Aminotran_4 PF01063.19 KEY72191.1 - 3.1e-26 92.6 0.0 4.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV CTP_transf_like PF01467.26 KEY72192.1 - 3e-08 34.0 0.0 0.00029 21.0 0.0 3.4 3 1 0 3 3 3 3 Cytidylyltransferase-like DUF3325 PF11804.8 KEY72193.1 - 0.0055 16.8 1.1 0.0081 16.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) His_Phos_1 PF00300.22 KEY72194.1 - 7.8e-10 38.8 0.1 4e-09 36.5 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4813 PF16072.5 KEY72195.1 - 0.045 13.4 7.6 0.091 12.4 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Herpes_pp85 PF04637.12 KEY72195.1 - 6.1 5.1 5.5 14 3.9 5.1 1.8 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PCRF PF03462.18 KEY72196.1 - 2.6e-44 151.4 0.1 6.8e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KEY72196.1 - 2.4e-34 117.7 4.2 2.4e-34 117.7 4.2 1.7 2 0 0 2 2 2 1 RF-1 domain Pec_lyase_C PF00544.19 KEY72197.1 - 1.4e-13 50.9 3.0 2.7e-12 46.7 3.0 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY72197.1 - 0.00049 20.0 3.6 0.0019 18.1 3.2 1.9 1 1 0 1 1 1 1 Right handed beta helix region NACHT PF05729.12 KEY72198.1 - 5.8e-09 36.1 0.0 1.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.6 KEY72198.1 - 4.4e-05 23.7 0.3 4.4e-05 23.7 0.3 5.2 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KEY72198.1 - 8.9e-05 22.7 34.5 0.00025 21.3 6.3 5.7 5 1 0 5 5 4 2 Zinc finger, C2H2 type AAA_16 PF13191.6 KEY72198.1 - 0.0003 21.2 0.0 0.0012 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain zf-C2H2_jaz PF12171.8 KEY72198.1 - 0.0033 17.7 11.1 0.06 13.7 2.9 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KEY72198.1 - 0.0068 17.2 27.5 0.039 14.8 4.3 5.6 5 0 0 5 5 5 1 C2H2-type zinc finger AAA_22 PF13401.6 KEY72198.1 - 0.014 15.7 0.0 0.076 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-met PF12874.7 KEY72198.1 - 0.016 15.5 11.7 0.085 13.3 2.3 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF676 PF05057.14 KEY72198.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Sprouty PF05210.13 KEY72198.1 - 0.14 12.5 0.7 0.39 11.1 0.7 1.8 1 0 0 1 1 1 0 Sprouty protein (Spry) C5HCH PF17982.1 KEY72198.1 - 0.86 9.8 6.0 0.42 10.8 1.9 2.4 2 0 0 2 2 2 0 NSD Cys-His rich domain zf-C2H2_11 PF16622.5 KEY72198.1 - 4.5 7.1 8.4 0.12 12.2 1.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KEY72198.1 - 9.2 6.8 15.8 0.15 12.5 1.2 4.2 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger SNF2_N PF00176.23 KEY72199.1 - 6.6e-50 169.8 0.0 9.1e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY72199.1 - 7.9e-12 45.5 0.0 2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY72199.1 - 3.2e-08 33.7 0.0 5.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEY72199.1 - 0.087 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase APH PF01636.23 KEY72200.1 - 1.1e-05 25.5 0.1 3.1e-05 24.0 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KEY72200.1 - 5.3e-05 22.7 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEY72200.1 - 9e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEY72200.1 - 0.0034 17.0 0.0 0.0086 15.7 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Methyltransf_24 PF13578.6 KEY72200.1 - 0.078 14.0 0.1 0.36 11.9 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Choline_kinase PF01633.20 KEY72200.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KEY72200.1 - 0.14 10.9 0.0 0.61 8.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF3576 PF12100.8 KEY72203.1 - 0.082 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) CENP-F_leu_zip PF10473.9 KEY72205.1 - 0.016 15.3 9.8 0.016 15.3 9.8 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KEY72205.1 - 0.025 14.9 8.2 9.4 6.6 0.9 4.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KEY72205.1 - 0.035 14.2 18.0 0.85 9.7 1.9 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KEY72205.1 - 0.066 13.2 14.9 0.49 10.4 1.8 3.7 1 1 3 4 4 4 0 Laminin Domain II Sec34 PF04136.15 KEY72205.1 - 1.1 9.1 5.1 0.72 9.7 0.1 2.7 2 1 1 3 3 3 0 Sec34-like family Baculo_PEP_C PF04513.12 KEY72205.1 - 3 7.9 10.6 1.2 9.2 3.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KEY72205.1 - 3.5 8.1 11.2 2.9 8.3 3.6 3.6 1 1 1 2 2 2 0 Syntaxin-like protein UPF0270 PF06794.12 KEY72205.1 - 4.4 7.5 8.6 13 6.0 0.2 4.0 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0270) BST2 PF16716.5 KEY72205.1 - 4.5 7.9 18.9 1.6 9.4 3.4 4.1 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 Lebercilin PF15619.6 KEY72205.1 - 8.3 6.0 28.0 1.3 8.7 1.8 3.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 KEY72205.1 - 8.3 4.2 10.0 0.55 8.1 1.6 2.2 1 1 0 2 2 2 0 Prominin DUF3357 PF11837.8 KEY72206.1 - 0.0071 16.8 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Pkinase PF00069.25 KEY72207.1 - 1e-23 84.1 0.0 2.1e-23 83.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72207.1 - 3.6e-15 56.0 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4246 PF14033.6 KEY72208.1 - 6.2e-157 523.3 0.0 1.3e-156 522.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KEY72208.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ArAE_2_N PF10337.9 KEY72209.1 - 1e-105 354.6 4.7 2.4e-105 353.3 0.1 2.5 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KEY72209.1 - 6.2e-55 186.5 0.0 1.6e-54 185.2 0.0 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KEY72209.1 - 2.8e-09 37.2 14.0 2.8e-09 37.2 14.0 3.6 2 2 2 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 KEY72209.1 - 0.0021 17.0 9.4 0.0021 17.0 9.4 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter cobW PF02492.19 KEY72210.1 - 1.9e-43 148.1 5.6 1e-31 109.9 0.5 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KEY72210.1 - 1.9e-17 62.9 0.4 3.7e-13 49.2 0.0 2.9 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain Peptidase_S51 PF03575.17 KEY72210.1 - 5.2e-14 52.4 0.0 9.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S51 MeaB PF03308.16 KEY72210.1 - 0.00014 20.9 0.1 0.23 10.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MPP6 PF10175.9 KEY72210.1 - 0.032 14.7 0.7 0.09 13.3 0.7 1.7 1 0 0 1 1 1 0 M-phase phosphoprotein 6 MobB PF03205.14 KEY72210.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RRN3 PF05327.11 KEY72210.1 - 0.23 9.9 4.9 0.38 9.2 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KEY72210.1 - 0.47 8.7 4.6 0.87 7.8 4.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KEY72210.1 - 0.73 7.8 2.1 1.1 7.2 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 KEY72210.1 - 3.4 6.9 8.5 5.7 6.2 8.5 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_M14 PF00246.24 KEY72212.1 - 4.7e-31 108.7 0.1 6.3e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ist1 PF03398.14 KEY72213.1 - 0.062 13.2 1.3 0.078 12.9 1.3 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway HET PF06985.11 KEY72214.1 - 2.8e-33 115.3 0.7 1.6e-32 112.9 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) IncFII_repA PF02387.15 KEY72215.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family CFEM PF05730.11 KEY72216.1 - 0.0013 18.8 1.9 0.0019 18.3 1.9 1.3 1 0 0 1 1 1 1 CFEM domain Cellulase PF00150.18 KEY72217.1 - 2.2e-16 60.1 0.1 2.9e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 KEY72218.1 - 1.4e-50 171.5 0.2 2e-50 171.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72218.1 - 5.8e-38 130.8 0.2 7.7e-38 130.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72218.1 - 4.7e-14 52.7 0.2 7.1e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY72218.1 - 2.1e-08 34.3 0.5 3.1e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KEY72218.1 - 8.9e-05 22.0 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY72218.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY72218.1 - 0.00018 21.7 0.1 0.00051 20.3 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KEY72218.1 - 0.009 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 KEY72218.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S58 PF03576.14 KEY72218.1 - 0.014 14.9 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S58 Fungal_trans PF04082.18 KEY72219.1 - 3.6e-13 49.2 0.0 5.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain peroxidase PF00141.23 KEY72220.1 - 1.2e-85 286.8 0.0 7.6e-44 150.1 0.0 2.2 2 0 0 2 2 2 2 Peroxidase DPPIV_N PF00930.21 KEY72221.1 - 0.058 12.1 0.0 0.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KEY72221.1 - 0.087 12.8 0.2 1.6 8.7 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 KEY72222.1 - 2.5e-06 27.5 9.5 4.3e-06 26.7 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY72222.1 - 0.0092 14.8 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KEY72223.1 - 6.6e-69 231.7 15.8 8.8e-69 231.2 15.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Frizzled PF01534.17 KEY72223.1 - 1.5 7.8 11.9 0.076 12.0 3.5 2.4 2 1 1 3 3 3 0 Frizzled/Smoothened family membrane region PEP-CTERM PF07589.11 KEY72223.1 - 2.3 8.5 7.0 13 6.1 0.3 3.5 3 0 0 3 3 3 0 PEP-CTERM motif Glyco_transf_28 PF03033.20 KEY72224.1 - 3.9e-20 72.3 0.0 9.5e-20 71.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KEY72224.1 - 0.0028 16.5 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PAG PF15347.6 KEY72224.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Glyco_tran_28_C PF04101.16 KEY72224.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KEY72224.1 - 0.15 12.5 0.1 5.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain FAD_binding_4 PF01565.23 KEY72225.1 - 2.2e-22 79.3 3.3 5e-22 78.1 2.6 2.0 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KEY72225.1 - 5.1e-10 39.3 1.0 1e-09 38.4 1.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like RTA1 PF04479.13 KEY72226.1 - 1e-70 237.5 10.0 1.5e-70 237.1 10.0 1.2 1 0 0 1 1 1 1 RTA1 like protein TssN PF17555.2 KEY72226.1 - 0.053 12.9 12.5 0.15 11.4 2.5 3.1 2 2 1 3 3 3 0 Type VI secretion system, TssN DUF4173 PF13777.6 KEY72226.1 - 8.2 5.8 15.9 0.028 13.9 5.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4173) Bac_rhamnosid6H PF17389.2 KEY72227.1 - 6.7e-14 51.9 0.1 1.9e-11 43.8 0.1 3.1 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KEY72227.1 - 0.0001 22.0 0.0 0.0013 18.5 0.0 2.8 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KEY72227.1 - 0.0037 16.1 0.0 0.0057 15.5 0.0 1.1 1 0 0 1 1 1 1 Trehalase HET PF06985.11 KEY72228.1 - 5.5e-34 117.6 0.3 8.8e-34 117.0 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.6 KEY72229.1 - 1.6e-08 35.3 0.0 4.5e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY72229.1 - 5.8e-06 26.7 0.0 1.3e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KEY72230.1 - 2.9e-09 36.9 7.1 6.3e-09 35.8 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RanBP PF00641.18 KEY72230.1 - 3.7 6.9 7.4 2 7.8 0.2 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others FAD_binding_4 PF01565.23 KEY72231.1 - 1.7e-16 60.2 4.1 1.7e-16 60.2 4.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY72231.1 - 7.8e-09 35.5 0.0 2.8e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Amidohydro_2 PF04909.14 KEY72232.1 - 1.8e-40 139.6 0.9 2e-40 139.4 0.9 1.0 1 0 0 1 1 1 1 Amidohydrolase MarR_2 PF12802.7 KEY72232.1 - 0.045 13.7 0.1 6 6.8 0.0 2.6 2 0 0 2 2 2 0 MarR family MFS_1 PF07690.16 KEY72233.1 - 5.5e-33 114.4 46.3 2.9e-19 69.2 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KEY72234.1 - 1.1e-59 202.4 0.0 1.4e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MLTR_LBD PF17765.1 KEY72234.1 - 0.018 15.2 0.1 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain ketoacyl-synt PF00109.26 KEY72235.1 - 2.1e-73 247.0 0.1 4.2e-73 246.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY72235.1 - 1.2e-34 118.8 0.2 2.8e-34 117.7 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEY72235.1 - 2.6e-28 99.5 0.1 4.8e-26 92.0 0.1 2.5 2 0 0 2 2 2 1 Acyl transferase domain HTH_51 PF18558.1 KEY72235.1 - 4e-21 74.7 0.0 1.4e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain PS-DH PF14765.6 KEY72235.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KEY72235.1 - 2.2e-18 66.3 7.4 1.8e-09 37.8 0.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEY72235.1 - 5e-13 49.6 0.0 1.4e-12 48.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KEY72235.1 - 6.8e-11 42.4 0.1 3.8e-10 40.0 0.1 2.3 2 1 0 2 2 1 1 alpha/beta hydrolase fold SAT PF16073.5 KEY72235.1 - 1.3e-10 41.5 3.3 3.7e-09 36.7 0.3 3.5 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_31 PF13847.6 KEY72235.1 - 1.4e-10 41.1 0.0 3.5e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Peptidase_S9 PF00326.21 KEY72235.1 - 2.3e-09 37.0 0.0 9e-07 28.6 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 KEY72235.1 - 6.4e-09 35.9 0.0 5.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY72235.1 - 4.4e-08 33.7 0.0 1.6e-07 32.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY72235.1 - 8.6e-07 29.4 0.0 2.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KEY72235.1 - 5.8e-06 26.9 0.0 5.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 KEY72235.1 - 1.1e-05 24.9 0.2 2.3e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KEY72235.1 - 1.5e-05 25.7 6.1 7.4e-05 23.5 2.0 3.1 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72235.1 - 0.00037 19.8 0.0 0.0074 15.6 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Methyltransf_PK PF05891.12 KEY72235.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase COesterase PF00135.28 KEY72235.1 - 0.02 13.8 0.0 0.039 12.8 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family Methyltransf_33 PF10017.9 KEY72235.1 - 0.029 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DLH PF01738.18 KEY72235.1 - 0.063 12.8 0.0 1.8 8.0 0.0 2.8 3 0 0 3 3 3 0 Dienelactone hydrolase family FSH1 PF03959.13 KEY72235.1 - 0.15 11.7 0.0 0.78 9.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) RrnaAD PF00398.20 KEY72235.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Trp_DMAT PF11991.8 KEY72236.1 - 6.2e-103 345.0 0.0 7.8e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Tannase PF07519.11 KEY72237.1 - 6.6e-78 262.7 0.0 1.1e-77 262.0 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEY72237.1 - 0.00024 20.7 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEY72237.1 - 0.0016 17.8 0.0 0.052 12.8 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY72237.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KEY72237.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase NAD_binding_10 PF13460.6 KEY72238.1 - 4.5e-08 33.2 0.0 6.8e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KEY72238.1 - 0.00015 21.9 0.3 0.00031 20.9 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KEY72238.1 - 0.00064 18.8 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEY72238.1 - 0.0028 18.1 0.0 0.005 17.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY72238.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEY72238.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Trp_halogenase PF04820.14 KEY72239.1 - 1.3e-27 96.8 0.1 1.3e-12 47.4 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEY72239.1 - 1.7e-12 47.3 0.0 3.2e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY72239.1 - 1.2e-05 25.5 1.2 2.6e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY72239.1 - 5e-05 22.8 1.0 9.8e-05 21.9 1.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72239.1 - 0.0001 21.7 0.0 0.00018 20.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY72239.1 - 0.0008 18.6 0.3 0.0008 18.6 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KEY72239.1 - 0.0022 17.1 0.4 0.0037 16.4 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEY72239.1 - 0.0035 16.1 0.1 0.0053 15.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KEY72239.1 - 0.0058 16.3 0.3 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY72239.1 - 0.013 14.8 0.0 0.084 12.1 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KEY72239.1 - 0.072 13.7 0.2 0.23 12.0 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY72239.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTC PF01137.21 KEY72240.1 - 5.3e-33 114.1 0.0 1.1e-32 113.1 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase FMO-like PF00743.19 KEY72241.1 - 9.5e-19 67.2 0.0 1.5e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY72241.1 - 4e-07 29.6 0.0 1.4e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY72241.1 - 4.1e-06 26.2 0.0 0.0002 20.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY72241.1 - 0.0027 17.0 0.0 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY72241.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NPR2 PF06218.11 KEY72241.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Fungal_trans_2 PF11951.8 KEY72242.1 - 1.2e-23 83.6 0.5 2.2e-23 82.7 0.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 KEY72243.1 - 5.8e-14 52.1 0.1 4.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY72243.1 - 2.8e-08 33.9 0.0 5.8e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KEY72243.1 - 7.8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY72243.1 - 0.00021 20.8 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEY72243.1 - 0.001 18.3 0.0 0.0023 17.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KEY72243.1 - 0.0013 17.8 0.0 0.005 15.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEY72243.1 - 0.022 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DAO PF01266.24 KEY72244.1 - 1.1e-36 127.2 0.2 1.3e-36 127.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY72244.1 - 4.6e-07 29.2 0.9 0.012 14.6 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY72244.1 - 6.5e-07 29.5 2.9 0.0017 18.4 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KEY72244.1 - 2.8e-05 23.2 0.1 0.0085 15.0 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 KEY72244.1 - 6.3e-05 22.4 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY72244.1 - 0.00081 19.6 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY72244.1 - 0.0039 16.5 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY72244.1 - 0.022 13.9 0.1 0.73 8.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KEY72244.1 - 0.033 13.4 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KEY72244.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KEY72244.1 - 0.12 11.6 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DUF2235 PF09994.9 KEY72245.1 - 3.8e-40 138.1 0.0 5e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Antimicrobial13 PF08108.11 KEY72246.1 - 0.16 12.1 0.4 0.3 11.2 0.4 1.4 1 0 0 1 1 1 0 Halocidin family BTB PF00651.31 KEY72247.1 - 0.001 19.2 0.0 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain LPMO_10 PF03067.15 KEY72248.1 - 1.6e-09 38.7 0.0 2.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sulfatase PF00884.23 KEY72249.1 - 1.9e-44 152.3 0.0 2.1e-42 145.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase ADH_zinc_N PF00107.26 KEY72249.1 - 0.051 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LPMO_10 PF03067.15 KEY72250.1 - 2e-09 38.4 0.0 2.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Methyltransf_2 PF00891.18 KEY72251.1 - 2e-17 63.2 0.0 2.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 KEY72251.1 - 5.2e-05 23.0 0.4 0.00015 21.5 0.4 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Dimerisation2 PF16864.5 KEY72251.1 - 0.00022 21.1 0.3 0.00046 20.1 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KEY72251.1 - 0.00026 20.9 0.5 0.00076 19.4 0.5 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KEY72251.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Rrf2 PF02082.20 KEY72251.1 - 0.017 15.5 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 KEY72251.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Acetyltransf_1 PF00583.25 KEY72251.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PQ-loop PF04193.14 KEY72252.1 - 6e-09 35.5 14.4 8.5e-05 22.3 1.1 3.2 3 0 0 3 3 3 2 PQ loop repeat DUF1440 PF07274.12 KEY72252.1 - 0.019 15.3 0.2 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DUF4064 PF13273.6 KEY72252.1 - 0.028 14.7 0.8 0.028 14.7 0.8 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) MtN3_slv PF03083.16 KEY72252.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.4 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF1240 PF06836.12 KEY72252.1 - 0.29 11.7 3.5 3.9 8.1 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) TraQ PF09679.10 KEY72252.1 - 2 8.4 4.7 1.5 8.8 2.2 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Aminotran_3 PF00202.21 KEY72253.1 - 2.4e-115 385.4 0.0 3e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KEY72254.1 - 2.1e-168 560.6 0.1 2.4e-168 560.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KEY72255.1 - 1.2e-34 119.8 21.4 1.6e-34 119.4 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEY72255.1 - 0.0097 15.6 2.9 0.0097 15.6 2.9 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 p450 PF00067.22 KEY72256.1 - 2.6e-63 214.4 0.0 3e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KEY72257.1 - 9.3e-14 51.9 0.0 1.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72257.1 - 2.6e-12 47.2 0.0 4.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72257.1 - 1.7e-11 44.2 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY72257.1 - 6.5e-10 39.6 0.0 1.1e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY72257.1 - 8.9e-09 35.4 0.0 1.5e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY72257.1 - 3.4e-05 23.5 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEY72257.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 KEY72257.1 - 0.0002 21.1 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_PK PF05891.12 KEY72257.1 - 0.00044 19.8 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KEY72257.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KEY72257.1 - 0.0095 15.3 0.0 0.018 14.3 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.17 KEY72257.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Spermine/spermidine synthase domain NodS PF05401.11 KEY72257.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) ketoacyl-synt PF00109.26 KEY72258.1 - 5.2e-66 222.8 0.0 8.4e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY72258.1 - 9.3e-59 198.4 0.0 2.7e-58 196.8 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEY72258.1 - 2.5e-42 145.2 0.0 4.7e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY72258.1 - 6.2e-42 144.2 0.0 1.1e-41 143.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY72258.1 - 2.6e-37 127.4 0.0 7.2e-37 126.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY72258.1 - 2.2e-14 53.8 0.0 2.5e-13 50.4 0.0 2.7 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KEY72258.1 - 2.8e-14 53.2 0.1 1.7e-13 50.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY72258.1 - 2e-12 48.3 0.0 1.1e-11 45.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEY72258.1 - 2e-11 44.1 0.2 2.1e-09 37.6 0.1 3.0 3 0 0 3 3 2 1 Phosphopantetheine attachment site adh_short PF00106.25 KEY72258.1 - 2.1e-10 40.4 0.0 5.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KEY72258.1 - 1.3e-07 32.3 0.0 3.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KEY72258.1 - 7.3e-07 29.2 0.4 3.4e-06 27.0 0.4 2.0 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 KEY72258.1 - 1.1e-06 28.5 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KEY72258.1 - 6.7e-06 25.8 0.0 3.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KEY72258.1 - 5e-05 23.1 0.0 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72258.1 - 0.0075 16.9 0.0 0.03 15.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY72258.1 - 0.01 16.6 0.0 0.056 14.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEY72258.1 - 0.037 13.4 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KEY72258.1 - 0.044 13.1 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KEY72258.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 KEY72258.1 - 0.19 11.6 0.4 0.53 10.2 0.4 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Aminotran_1_2 PF00155.21 KEY72259.1 - 1.5e-26 93.5 0.0 1.8e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KEY72259.1 - 0.0023 16.7 0.0 0.0082 14.9 0.0 1.9 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KEY72259.1 - 0.0068 15.0 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sulfotransfer_4 PF17784.1 KEY72260.1 - 1.2e-54 185.4 0.0 1.4e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY72260.1 - 0.00027 21.4 0.0 0.0011 19.4 0.0 1.7 1 1 1 2 2 2 1 Sulfotransferase family K_oxygenase PF13434.6 KEY72260.1 - 0.077 12.1 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.16 KEY72261.1 - 1.7e-37 129.2 14.4 1.7e-37 129.2 14.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 KEY72262.1 - 1.6e-30 106.4 0.1 2.8e-30 105.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_6 PF01341.17 KEY72263.1 - 1.7e-93 313.7 0.0 2.1e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Pectinesterase PF01095.19 KEY72263.1 - 0.12 11.1 0.2 0.17 10.5 0.2 1.1 1 0 0 1 1 1 0 Pectinesterase MFS_1 PF07690.16 KEY72264.1 - 4.1e-18 65.4 11.3 5.3e-18 65.1 11.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KEY72264.1 - 0.33 11.3 2.1 0.6 10.5 0.1 2.4 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V FMN_dh PF01070.18 KEY72265.1 - 1.8e-103 346.2 0.0 2.1e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KEY72265.1 - 0.0021 17.1 0.2 0.0041 16.2 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEY72265.1 - 0.0023 17.1 0.1 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KEY72265.1 - 0.034 13.6 0.2 0.1 12.0 0.1 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein LuxQ-periplasm PF09308.10 KEY72265.1 - 0.21 11.1 0.1 0.34 10.4 0.1 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic MFS_1 PF07690.16 KEY72267.1 - 1.7e-25 89.7 51.0 1.7e-25 89.7 51.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily N2227 PF07942.12 KEY72267.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Exo_endo_phos PF03372.23 KEY72268.1 - 4.4e-08 32.9 0.1 2.6e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF347 PF03988.12 KEY72269.1 - 0.091 13.0 0.3 0.091 13.0 0.3 3.6 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) Phage_holin_5_2 PF16079.5 KEY72269.1 - 3.4 8.1 9.7 0.23 11.8 0.6 3.2 4 0 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V DUF4246 PF14033.6 KEY72270.1 - 1.6e-169 564.8 0.2 2.1e-169 564.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.6 KEY72270.1 - 0.0016 19.3 0.0 0.0035 18.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 KEY72270.1 - 0.0032 17.8 0.4 0.0076 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase Fungal_trans_2 PF11951.8 KEY72271.1 - 6.9e-08 31.7 0.1 1.2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY72272.1 - 5.7e-23 81.4 0.1 1.1e-18 67.5 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72272.1 - 1.6e-13 50.8 0.0 4.2e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72272.1 - 0.00019 21.4 0.3 0.00029 20.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEY72272.1 - 0.054 13.8 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Phytochelatin_C PF09328.10 KEY72272.1 - 0.12 11.6 1.8 0.096 12.0 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) FAD_binding_3 PF01494.19 KEY72273.1 - 8.8e-74 248.8 0.0 2e-73 247.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEY72273.1 - 5.6e-23 81.8 0.0 9.8e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KEY72273.1 - 5.4e-06 25.7 1.2 6.2e-05 22.2 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEY72273.1 - 7.5e-05 22.5 0.1 0.00081 19.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72273.1 - 0.00015 21.1 0.1 0.00025 20.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY72273.1 - 0.00029 21.0 0.2 0.00072 19.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEY72273.1 - 0.00033 19.9 0.1 0.00054 19.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KEY72273.1 - 0.00069 18.9 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KEY72273.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEY72273.1 - 0.0014 17.9 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY72273.1 - 0.0066 15.8 0.4 0.01 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY72273.1 - 0.007 15.1 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KEY72273.1 - 0.067 12.2 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Cellulase PF00150.18 KEY72274.1 - 1e-17 64.5 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KEY72274.1 - 1.1e-11 44.4 16.1 1.1e-11 44.4 16.1 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KEY72274.1 - 0.003 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KEY72274.1 - 0.022 14.1 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase Toxin_7 PF05980.12 KEY72274.1 - 0.77 10.1 3.0 2.2 8.6 3.0 1.7 1 0 0 1 1 1 0 Toxin 7 Fungal_trans PF04082.18 KEY72275.1 - 2.8e-22 79.0 0.4 5.4e-22 78.1 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72275.1 - 2.5e-06 27.5 13.8 4.3e-06 26.7 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3938 PF13074.6 KEY72276.1 - 0.0076 16.5 1.3 0.0091 16.2 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3938) p450 PF00067.22 KEY72277.1 - 5.7e-41 140.7 0.0 7.1e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C PF00043.25 KEY72278.1 - 1.8e-10 40.9 0.0 2.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEY72278.1 - 1.8e-09 37.8 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY72278.1 - 3.7e-07 30.1 0.1 6.9e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY72278.1 - 4.5e-07 30.0 0.1 8.7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEY72278.1 - 0.0021 18.4 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY72278.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short PF00106.25 KEY72279.1 - 1.2e-16 60.7 0.1 4.1e-16 59.0 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72279.1 - 1.3e-08 34.7 0.1 2.7e-08 33.7 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72279.1 - 8.6e-08 32.3 0.5 1.7e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY72280.1 - 1.7e-17 63.9 0.0 2.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY72280.1 - 7.9e-07 28.9 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KEY72280.1 - 0.0046 16.0 0.1 0.0061 15.6 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY72280.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein NAD_Gly3P_dh_N PF01210.23 KEY72280.1 - 0.036 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 KEY72280.1 - 0.097 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Questin_oxidase PF14027.6 KEY72281.1 - 1.7e-82 277.8 0.3 2e-82 277.5 0.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like AMP-binding PF00501.28 KEY72282.1 - 1.1e-55 188.9 0.0 1.4e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1772 PF08592.11 KEY72283.1 - 7.3e-28 97.6 11.7 9.8e-28 97.2 11.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Glucos_trans_II PF14264.6 KEY72283.1 - 0.0014 18.1 0.3 0.0019 17.6 0.3 1.4 1 1 0 1 1 1 1 Glucosyl transferase GtrII DUF2834 PF11196.8 KEY72283.1 - 0.75 10.2 6.3 0.5 10.7 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) DUF3188 PF11384.8 KEY72283.1 - 6 6.7 6.2 4.3 7.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) EthD PF07110.11 KEY72284.1 - 4.4e-21 75.8 0.4 5.8e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KEY72284.1 - 0.00048 20.6 0.1 0.00069 20.1 0.1 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Ribosomal_L26 PF16906.5 KEY72284.1 - 0.17 12.4 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Scytalone_dh PF02982.14 KEY72285.1 - 2.3e-66 222.5 2.6 2.8e-66 222.2 2.6 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KEY72285.1 - 2.6e-09 37.3 3.0 3.5e-09 36.9 3.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HNOB PF07700.15 KEY72285.1 - 0.056 13.4 0.0 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Haem-NO-binding GMC_oxred_N PF00732.19 KEY72286.1 - 2e-44 152.2 0.0 2.8e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY72286.1 - 3.9e-31 108.5 0.0 6.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEY72286.1 - 1.7e-07 30.8 0.0 0.00036 19.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY72286.1 - 9.4e-06 25.8 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY72286.1 - 4.2e-05 23.3 0.7 0.00042 20.0 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY72286.1 - 0.00021 20.5 0.0 0.00056 19.1 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEY72286.1 - 0.0013 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEY72286.1 - 0.0019 17.0 0.0 0.015 14.0 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.14 KEY72286.1 - 0.0061 15.5 0.0 0.033 13.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KEY72286.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEY72286.1 - 0.023 13.9 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY72286.1 - 0.044 14.4 0.1 0.14 12.7 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY72286.1 - 0.091 12.0 0.1 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Aldo_ket_red PF00248.21 KEY72287.1 - 1.4e-60 205.0 0.0 1.6e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ketoacyl-synt PF00109.26 KEY72288.1 - 1.8e-72 244.0 0.0 1.8e-72 244.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KEY72288.1 - 1.5e-42 146.0 0.4 8.8e-41 140.2 0.0 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KEY72288.1 - 1.9e-36 126.2 0.0 6.1e-36 124.5 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY72288.1 - 1.2e-32 112.4 2.3 4.8e-32 110.5 2.3 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEY72288.1 - 1.1e-11 44.9 0.8 2.8e-11 43.6 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.6 KEY72288.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KEY72288.1 - 5.6e-10 39.7 0.0 1.6e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY72288.1 - 0.00026 20.4 0.1 0.00074 19.0 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF4775 PF16001.5 KEY72288.1 - 2.1 7.7 13.3 3.5 6.9 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Lactamase_B PF00753.27 KEY72289.1 - 4.2e-16 59.6 6.7 1.3e-14 54.6 6.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY72289.1 - 6.9e-05 22.5 1.0 0.00014 21.4 1.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KEY72289.1 - 0.0001 22.2 0.0 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Trp_DMAT PF11991.8 KEY72290.1 - 1e-89 301.5 0.0 1.3e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AflR PF08493.10 KEY72291.1 - 5e-16 59.0 1.3 5e-16 59.0 1.3 2.3 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KEY72291.1 - 4.7e-08 33.0 11.8 7.2e-08 32.4 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KEY72292.1 - 8e-55 185.9 0.8 1e-54 185.6 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY72292.1 - 6.9e-48 162.7 0.4 8.3e-48 162.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY72292.1 - 3e-11 43.6 0.2 4.1e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KEY72292.1 - 0.071 12.4 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KEY72292.1 - 0.083 12.2 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY72292.1 - 0.14 11.6 0.4 1.1 8.6 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ABC2_membrane PF01061.24 KEY72295.1 - 4.4e-75 251.7 57.5 1.3e-40 139.1 16.4 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KEY72295.1 - 1.2e-36 126.2 0.0 1.3e-17 64.6 0.0 3.4 3 1 1 4 4 4 2 ABC transporter PDR_CDR PF06422.12 KEY72295.1 - 4e-34 116.4 9.2 1.8e-30 104.6 0.0 3.9 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY72295.1 - 5.6e-14 52.5 1.3 1.2e-13 51.5 0.1 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEY72295.1 - 2.9e-07 29.9 40.5 7e-05 22.1 14.9 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_33 PF13671.6 KEY72295.1 - 1.9e-06 28.1 0.0 0.048 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY72295.1 - 4.7e-06 26.6 0.0 0.002 18.1 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KEY72295.1 - 1.2e-05 25.7 0.1 0.063 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KEY72295.1 - 2.9e-05 23.7 0.0 0.00058 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY72295.1 - 4.7e-05 23.9 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY72295.1 - 0.00017 21.3 0.5 0.044 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KEY72295.1 - 0.00018 22.0 0.3 0.15 12.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY72295.1 - 0.0046 17.2 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY72295.1 - 0.0081 16.1 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 KEY72295.1 - 0.0081 16.0 0.0 1.5 8.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY72295.1 - 0.011 15.2 0.0 0.81 9.1 0.0 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEY72295.1 - 0.018 14.8 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEY72295.1 - 0.022 15.0 0.1 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KEY72295.1 - 0.028 14.3 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 KEY72295.1 - 0.034 13.7 0.1 2 8.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KEY72295.1 - 0.035 14.5 0.0 17 5.8 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 KEY72296.1 - 2.7e-22 79.2 0.1 4.3e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72296.1 - 1.4e-14 54.2 0.2 3.1e-14 53.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72296.1 - 1.2e-07 31.8 0.2 1.9e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY72296.1 - 2.5e-07 30.4 0.1 1.2e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY72296.1 - 0.00026 20.9 0.4 0.00037 20.4 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Peripla_BP_6 PF13458.6 KEY72296.1 - 0.0077 15.9 1.3 0.014 15.1 1.1 1.4 1 1 0 1 1 1 1 Periplasmic binding protein ERp29_N PF07912.13 KEY72296.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain Fungal_trans PF04082.18 KEY72297.1 - 1.1e-11 44.3 0.1 1.7e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72297.1 - 4.7e-08 33.0 12.1 8.8e-08 32.1 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEY72298.1 - 1.9e-35 122.5 34.3 8.7e-35 120.3 34.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY72298.1 - 0.0008 18.4 8.4 0.0008 18.4 8.4 1.6 1 1 1 2 2 2 1 MFS_1 like family ESSS PF10183.9 KEY72298.1 - 0.018 15.3 0.2 1.3 9.3 0.0 3.2 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 KEY72300.1 - 3.9e-37 128.0 53.7 3.9e-37 128.0 53.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1418 PF07214.12 KEY72300.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) ATP_synth_reg PF14960.6 KEY72300.1 - 1.3 8.6 3.6 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase regulation DUF2057 PF09829.9 KEY72301.1 - 1.2 9.3 4.6 1.8 8.7 4.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Cutinase PF01083.22 KEY72302.1 - 3.4e-46 157.4 0.0 5.3e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEY72302.1 - 9.2e-05 22.1 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain Lipase PF00151.19 KEY72302.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipase Abhydrolase_2 PF02230.16 KEY72302.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KEY72302.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MGC-24 PF05283.11 KEY72302.1 - 0.15 12.5 3.0 0.24 11.8 3.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 KEY72302.1 - 0.29 11.1 14.8 0.48 10.4 14.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 KEY72302.1 - 0.7 8.0 11.7 1 7.5 11.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FIN1 PF17300.2 KEY72304.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Pre-PUA PF17832.1 KEY72305.1 - 4.2e-21 75.4 0.5 6e-21 74.9 0.5 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KEY72305.1 - 3.4e-12 46.1 0.1 1e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.8 KEY72306.1 - 1.3e-08 34.8 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KEY72306.1 - 0.011 16.4 0.1 0.014 16.0 0.1 1.3 1 1 0 1 1 1 0 Potato inhibitor I family LapA_dom PF06305.11 KEY72307.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NST1 PF13945.6 KEY72308.1 - 1e-47 162.8 14.9 1e-47 162.8 14.9 5.2 2 2 1 3 3 3 1 Salt tolerance down-regulator Ras PF00071.22 KEY72309.1 - 8.4e-50 168.5 0.0 9.8e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY72309.1 - 3.8e-21 75.5 0.0 5.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY72309.1 - 6.3e-06 25.8 0.0 9.7e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEY72309.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEY72309.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KEY72309.1 - 0.092 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 KEY72309.1 - 0.12 12.1 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KEY72309.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KEY72309.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MRP-L28 PF09812.9 KEY72310.1 - 0.00014 22.0 0.2 0.00021 21.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PGC7_Stella PF15549.6 KEY72310.1 - 0.11 12.5 2.5 0.15 12.1 2.5 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain ADP_ribosyl_GH PF03747.14 KEY72311.1 - 1.8e-58 198.6 0.2 2.1e-58 198.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KEY72311.1 - 0.37 10.7 9.2 2.2 8.2 0.3 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain Lipase_GDSL_2 PF13472.6 KEY72312.1 - 3.9e-13 50.2 0.9 5.3e-13 49.8 0.9 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY72312.1 - 5.1e-08 33.1 0.1 1.5e-07 31.6 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KEY72312.1 - 0.024 14.3 0.2 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX BET PF17035.5 KEY72315.1 - 0.01 16.0 0.0 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation EF-hand_8 PF13833.6 KEY72315.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair FAD_binding_2 PF00890.24 KEY72316.1 - 1.7e-96 323.8 0.5 2e-96 323.7 0.5 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY72316.1 - 2.5e-07 30.8 0.1 9e-07 29.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY72316.1 - 1.3e-05 24.9 3.0 7.7e-05 22.4 3.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY72316.1 - 2.1e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY72316.1 - 8.7e-05 21.9 0.1 0.00056 19.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY72316.1 - 0.00017 20.4 2.3 0.0039 15.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KEY72316.1 - 0.00034 19.8 0.1 0.0007 18.8 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KEY72316.1 - 0.00089 18.6 0.1 0.0073 15.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KEY72316.1 - 0.0045 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY72316.1 - 0.054 12.5 0.2 0.085 11.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY72316.1 - 0.11 12.5 2.0 0.14 12.1 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KEY72316.1 - 0.18 11.0 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KEY72317.1 - 9.7e-16 57.6 18.0 9.7e-16 57.6 18.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfotransfer_4 PF17784.1 KEY72318.1 - 2.7e-72 243.1 0.2 3.3e-72 242.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY72318.1 - 6.5e-05 23.4 0.1 0.013 15.9 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family Pkinase PF00069.25 KEY72320.1 - 1.1e-48 166.0 0.0 2e-47 161.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72320.1 - 5.7e-27 94.6 0.0 5.2e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY72320.1 - 0.00054 19.4 0.0 1.9 7.7 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KEY72320.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEY72320.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEY72320.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KEY72320.1 - 0.008 15.8 0.0 0.19 11.3 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 UL11 PF11094.8 KEY72320.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Haspin_kinase PF12330.8 KEY72320.1 - 0.098 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KEY72320.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KEY72320.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KEY72322.1 - 2.5e-53 181.2 0.1 3.4e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72322.1 - 2.4e-25 89.3 0.0 7.4e-25 87.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KEY72322.1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KEY72322.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KEY72322.1 - 0.048 13.0 0.4 0.085 12.2 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMA7 PF09072.10 KEY72323.1 - 1.6e-27 96.1 18.6 1.8e-27 95.9 18.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 HlyIII PF03006.20 KEY72324.1 - 6.1e-66 222.3 14.6 7.3e-66 222.1 14.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.11 KEY72324.1 - 1.5 9.0 10.3 4.5 7.5 0.9 3.4 2 1 2 4 4 4 0 Ycf66 protein N-terminus ANAPC4_WD40 PF12894.7 KEY72325.1 - 0.00015 22.0 0.1 0.42 10.9 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY72325.1 - 1.3 10.1 3.9 95 4.1 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat SnoaL_2 PF12680.7 KEY72326.1 - 7.1e-10 39.4 0.0 8.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KEY72326.1 - 0.041 14.3 0.0 0.059 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KEY72326.1 - 0.054 13.6 0.0 0.082 13.0 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Glyco_hydro_61 PF03443.14 KEY72327.1 - 4.4e-50 170.5 0.0 6.7e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ANAPC3 PF12895.7 KEY72328.1 - 0.0053 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 adh_short_C2 PF13561.6 KEY72329.1 - 6.1e-49 166.7 3.3 5.5e-39 134.1 1.7 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY72329.1 - 2.5e-44 151.1 1.9 3.3e-44 150.7 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY72329.1 - 3.1e-15 56.6 0.2 4.2e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY72329.1 - 0.0023 17.8 0.4 0.0037 17.2 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KEY72329.1 - 0.04 14.0 0.4 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEY72329.1 - 0.082 12.5 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.26 KEY72330.1 - 1.2e-34 119.6 0.0 1.4e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEY72330.1 - 5.3e-14 52.7 0.0 7.9e-14 52.1 0.0 1.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEY72330.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KEY72330.1 - 9.7e-05 22.0 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RSN1_7TM PF02714.15 KEY72332.1 - 7.2e-80 268.2 18.4 1.2e-79 267.5 18.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KEY72332.1 - 7.7e-41 140.2 0.0 1.1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KEY72332.1 - 3.3e-39 134.1 3.8 9.1e-39 132.7 3.8 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport AATase PF07247.12 KEY72333.1 - 4.2e-19 68.5 0.0 1.6e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 KEY72333.1 - 0.0052 16.6 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KEY72333.1 - 0.22 10.2 0.1 1.3 7.6 0.1 2.1 2 1 0 2 2 2 0 Condensation domain UQ_con PF00179.26 KEY72334.1 - 7.1e-38 129.4 0.0 1.2e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CDK2AP PF09806.9 KEY72334.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RIIa PF02197.17 KEY72334.1 - 0.16 11.7 1.0 0.45 10.2 1.0 1.8 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Nop52 PF05997.12 KEY72335.1 - 1.1e-52 179.0 0.0 1.3e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 ABC_cobalt PF09819.9 KEY72335.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component RabGAP-TBC PF00566.18 KEY72336.1 - 7.5e-33 114.0 0.1 1.4e-15 57.6 0.0 3.5 4 0 0 4 4 4 3 Rab-GTPase-TBC domain LZ_Tnp_IS66 PF13007.7 KEY72336.1 - 1.4 9.7 5.0 0.9 10.4 0.1 3.1 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain HLH PF00010.26 KEY72338.1 - 9.5e-09 35.1 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Retinal PF15449.6 KEY72338.1 - 3.3 5.4 19.1 4.6 4.9 19.1 1.1 1 0 0 1 1 1 0 Retinal protein Ndc1_Nup PF09531.10 KEY72338.1 - 3.5 6.2 6.6 3.9 6.1 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HIT PF01230.23 KEY72339.1 - 1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEY72339.1 - 4.4e-05 23.9 0.0 8.6e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KEY72339.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KEY72340.1 - 3.6e-10 39.3 1.6 5.7e-10 38.7 1.6 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KEY72340.1 - 0.00034 20.7 0.2 0.00071 19.6 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain Lar_restr_allev PF14354.6 KEY72340.1 - 0.0061 16.9 0.8 0.32 11.4 0.1 2.1 1 1 1 2 2 2 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 KEY72340.1 - 0.012 15.1 0.2 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 KEY72340.1 - 0.015 15.3 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KEY72340.1 - 0.018 15.0 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ISL3 PF14690.6 KEY72340.1 - 0.021 15.4 0.7 0.096 13.4 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PhnA_Zn_Ribbon PF08274.12 KEY72340.1 - 0.029 14.3 0.4 0.045 13.7 0.4 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-C2HC5 PF06221.13 KEY72340.1 - 0.029 14.3 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_9 PF14369.6 KEY72340.1 - 0.031 14.5 1.5 0.071 13.4 1.3 1.7 1 1 1 2 2 2 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KEY72340.1 - 0.038 14.0 3.0 0.55 10.3 3.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.19 KEY72340.1 - 0.039 14.3 0.6 0.14 12.5 0.8 1.4 1 1 1 2 2 2 0 DnaJ central domain YacG PF03884.14 KEY72340.1 - 0.055 13.2 0.2 0.6 9.9 0.1 2.4 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-TFIIB PF13453.6 KEY72340.1 - 0.064 12.6 0.8 8.8 5.8 0.4 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-Mss51 PF13824.6 KEY72340.1 - 0.22 11.6 1.1 2.1 8.5 0.0 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF35_N PF12172.8 KEY72340.1 - 0.45 10.4 4.2 6.7 6.7 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_recom PF13408.6 KEY72340.1 - 0.77 10.3 5.1 2.1 8.9 0.6 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 KEY72340.1 - 1.3 9.0 5.1 3.2 7.7 0.4 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain ATP_bind_1 PF03029.17 KEY72341.1 - 8.3e-62 209.1 0.0 1.1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KEY72341.1 - 0.026 14.1 0.0 0.089 12.3 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KEY72341.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B ChAPs PF09295.10 KEY72342.1 - 2.3e-151 504.3 0.0 2.3e-151 504.3 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 KEY72342.1 - 2e-05 24.3 0.3 0.16 12.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY72342.1 - 6.5e-05 22.8 0.0 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEY72342.1 - 0.00015 21.8 0.4 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY72342.1 - 0.00033 21.2 4.4 0.17 12.8 0.3 4.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY72342.1 - 0.00042 20.2 1.4 0.036 14.2 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY72342.1 - 0.0041 16.9 0.3 1.8 8.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEY72342.1 - 0.011 15.0 1.1 0.038 13.2 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEY72342.1 - 0.038 14.3 0.2 7.6 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY72342.1 - 0.055 14.1 0.0 13 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY72342.1 - 0.22 12.1 1.0 13 6.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.22 KEY72344.1 - 6.3e-72 240.7 0.1 8e-72 240.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KEY72344.1 - 0.0015 18.6 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.17 KEY72344.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DEAD PF00270.29 KEY72345.1 - 1.1e-45 155.6 0.0 1.7e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY72345.1 - 4.8e-31 107.4 0.1 1.7e-30 105.6 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY72345.1 - 1.5e-05 25.1 0.0 4.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Brix PF04427.18 KEY72346.1 - 2.6e-47 161.4 0.0 3.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain PP2C PF00481.21 KEY72346.1 - 9.6e-31 107.3 0.0 2.2e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEY72346.1 - 0.0012 18.8 0.1 0.22 11.4 0.0 3.1 1 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) AP3D1 PF06375.11 KEY72346.1 - 0.041 14.1 10.0 0.29 11.4 10.4 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PPL5 PF18168.1 KEY72346.1 - 0.29 10.4 5.9 0.56 9.4 5.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF1910 PF08928.10 KEY72346.1 - 0.99 9.4 3.3 2.1 8.4 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) TT_ORF2 PF02957.15 KEY72346.1 - 1.6 9.7 7.2 7.1 7.6 7.2 2.2 1 0 0 1 1 1 0 TT viral ORF2 Vfa1 PF08432.10 KEY72346.1 - 5.1 7.4 12.8 11 6.3 12.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CSRNP_N PF16019.5 KEY72346.1 - 8.6 6.2 8.2 1.9 8.4 4.7 1.6 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus TFIIB PF00382.19 KEY72347.1 - 1e-29 102.4 0.6 8.3e-19 67.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KEY72347.1 - 4.5e-23 81.5 1.5 4.5e-23 81.5 1.5 2.7 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KEY72347.1 - 0.00011 21.9 0.7 0.018 14.8 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF1349 PF07081.11 KEY72348.1 - 2e-19 70.0 0.0 4.1e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) NADH_dh_m_C1 PF15088.6 KEY72348.1 - 0.042 13.5 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial BTB PF00651.31 KEY72349.1 - 3.5e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KEY72349.1 - 0.00071 19.7 0.0 0.084 13.1 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain EPO_TPO PF00758.18 KEY72349.1 - 0.07 13.2 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Erythropoietin/thrombopoietin DHHC PF01529.20 KEY72350.1 - 2.2 8.4 13.0 7.1 6.7 0.7 3.5 2 1 1 3 3 3 0 DHHC palmitoyltransferase CsbD PF05532.12 KEY72351.1 - 5.3e-09 35.8 12.3 7.2e-05 22.6 2.7 2.1 1 1 1 2 2 2 2 CsbD-like Peptidase_S24 PF00717.23 KEY72352.1 - 1.7e-08 34.3 0.1 2.6e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like MTABC_N PF16185.5 KEY72353.1 - 0.047 13.2 0.2 0.047 13.2 0.2 1.5 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Kinesin PF00225.23 KEY72354.1 - 2.7e-55 187.6 0.0 1.1e-54 185.6 0.0 2.0 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEY72354.1 - 7.1e-09 35.8 0.0 1.7e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Herpes_BLRF2 PF05812.12 KEY72354.1 - 0.03 14.4 3.3 0.055 13.6 0.1 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 KEY72354.1 - 4.1 7.6 6.4 4.2 7.5 1.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 KEY72354.1 - 7.8 6.7 16.3 56 3.9 2.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MetOD1 PF18546.1 KEY72355.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Metanogen output domain 1 DEAD PF00270.29 KEY72356.1 - 1.2e-09 38.2 0.1 4.2e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY72356.1 - 1.7e-09 38.0 0.1 5.5e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEY72356.1 - 3.7e-05 24.0 0.0 8.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KEY72356.1 - 0.00026 21.3 0.0 0.00089 19.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEY72356.1 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_19 PF13245.6 KEY72356.1 - 0.004 17.5 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY72356.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KEY72356.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 Helicase ABATE PF07336.11 KEY72356.1 - 0.051 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative stress-induced transcription regulator RRM_1 PF00076.22 KEY72357.1 - 0.0035 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 KEY72358.1 - 1.5e-27 96.3 0.0 6.2e-27 94.4 0.0 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KEY72358.1 - 2.4e-24 85.5 0.0 3.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 KEY72358.1 - 0.066 13.6 0.2 4.5 7.8 0.1 3.1 2 0 0 2 2 2 0 Fumarase C C-terminus Abhydrolase_1 PF00561.20 KEY72359.1 - 1e-09 38.4 0.0 3.2e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY72359.1 - 1.3e-05 24.5 0.0 0.00077 18.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FA_hydroxylase PF04116.13 KEY72360.1 - 7.6e-10 39.3 5.4 7.6e-10 39.3 5.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3808 PF10300.9 KEY72361.1 - 1e-118 397.1 0.0 1.4e-118 396.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.13 KEY72363.1 - 2e-23 82.2 17.3 2.7e-23 81.8 17.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 KEY72363.1 - 0.33 10.7 10.0 0.34 10.6 10.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGK PF00162.19 KEY72364.1 - 7.8e-152 505.6 0.9 8.8e-152 505.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KEY72364.1 - 9.3e-06 25.6 0.0 0.0014 18.6 0.0 3.0 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 KEY72364.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Peripla_BP_4 PF13407.6 KEY72364.1 - 0.01 15.5 1.2 0.025 14.2 1.2 1.6 1 0 0 1 1 1 0 Periplasmic binding protein domain FIVAR PF07554.13 KEY72364.1 - 0.018 15.8 0.1 27 5.6 0.0 4.0 4 0 0 4 4 4 0 FIVAR domain Mpv17_PMP22 PF04117.12 KEY72365.1 - 5.6e-21 74.5 0.2 1.4e-20 73.3 0.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family NMD3 PF04981.13 KEY72366.1 - 1.5e-76 257.1 2.5 2.1e-76 256.6 2.5 1.2 1 0 0 1 1 1 1 NMD3 family DUF4470 PF14737.6 KEY72369.1 - 1.1e-15 57.6 0.0 2.4e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 KEY72369.1 - 2.4e-09 36.6 4.8 0.00073 19.5 1.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEY72369.1 - 4.8e-09 35.8 0.3 3.2e-05 23.5 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 KEY72369.1 - 3.4e-06 26.6 2.9 0.00057 19.6 0.7 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY72369.1 - 9.6e-06 25.8 1.5 0.042 14.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY72369.1 - 1.5e-05 25.6 1.6 1.5e-05 25.6 1.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY72369.1 - 5.6e-05 23.6 4.4 0.34 11.8 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY72369.1 - 0.0002 21.3 2.6 0.22 11.8 0.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY72369.1 - 0.00034 21.0 7.0 0.0044 17.5 0.9 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY72369.1 - 0.0014 18.4 0.5 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY72369.1 - 0.092 12.8 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEY72369.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_membrane PF00664.23 KEY72370.1 - 4e-57 194.0 31.0 1.3e-31 110.3 17.9 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KEY72370.1 - 2e-49 167.6 0.0 2.1e-29 102.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY72370.1 - 2.5e-08 33.7 0.1 0.011 15.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEY72370.1 - 1.6e-06 28.1 0.4 0.018 15.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY72370.1 - 8.5e-06 26.2 0.0 0.047 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY72370.1 - 0.00013 21.6 1.0 0.32 10.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY72370.1 - 0.0002 21.3 2.7 0.32 10.8 0.1 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY72370.1 - 0.00021 21.9 0.1 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KEY72370.1 - 0.00049 19.1 1.0 0.095 11.6 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KEY72370.1 - 0.00057 19.2 1.7 0.62 9.3 0.2 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KEY72370.1 - 0.00093 19.1 0.6 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KEY72370.1 - 0.00097 19.2 1.3 0.073 13.1 0.2 2.5 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 KEY72370.1 - 0.0013 18.9 2.5 0.032 14.3 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KEY72370.1 - 0.0026 17.5 2.1 0.39 10.4 0.4 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEY72370.1 - 0.006 16.9 0.5 5 7.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KEY72370.1 - 0.011 14.7 1.7 0.04 12.9 0.3 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 KEY72370.1 - 0.012 14.8 0.1 0.79 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KEY72370.1 - 0.013 14.7 1.3 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KEY72370.1 - 0.016 14.8 2.2 0.18 11.4 0.1 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KEY72370.1 - 0.017 15.0 0.5 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 KEY72370.1 - 0.022 14.5 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KEY72370.1 - 0.025 14.1 0.2 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KEY72370.1 - 0.027 13.5 0.0 0.53 9.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 KEY72370.1 - 0.045 14.0 0.1 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KEY72370.1 - 0.08 13.4 0.1 10 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEY72370.1 - 0.1 12.3 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEY72370.1 - 0.13 12.1 1.4 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 KEY72370.1 - 0.21 11.3 0.5 22 4.7 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 KEY72370.1 - 0.28 11.1 1.8 6 6.7 0.1 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 DUF2075 PF09848.9 KEY72370.1 - 0.35 10.1 2.0 23 4.1 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 KEY72370.1 - 0.47 10.2 3.4 17 5.1 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KEY72370.1 - 4.1 7.0 5.1 17 5.0 0.2 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DPPIV_N PF00930.21 KEY72372.1 - 6.5e-102 340.9 0.2 9.4e-102 340.4 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KEY72372.1 - 2.9e-36 124.9 0.8 5.4e-36 124.1 0.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY72372.1 - 0.00039 21.1 2.3 0.00091 19.9 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72372.1 - 0.0021 17.4 0.0 0.0058 15.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KEY72372.1 - 0.0022 17.2 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KEY72372.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S8 PF00082.22 KEY72372.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Subtilase family Cerato-platanin PF07249.12 KEY72373.1 - 0.00022 21.3 0.7 0.00079 19.5 0.1 1.9 2 0 0 2 2 2 1 Cerato-platanin GDP_Man_Dehyd PF16363.5 KEY72376.1 - 3.5e-46 158.2 0.0 5.6e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEY72376.1 - 5.4e-41 140.6 0.0 8.3e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Na_Ca_ex PF01699.24 KEY72376.1 - 2.1e-30 105.7 36.5 2.1e-18 66.7 16.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 3Beta_HSD PF01073.19 KEY72376.1 - 8e-07 28.3 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY72376.1 - 2e-05 23.9 0.0 0.0043 16.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KEY72376.1 - 0.19 10.9 0.0 2.9 6.9 0.0 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_88 PF07470.13 KEY72377.1 - 1.5e-67 228.2 3.5 1.8e-67 227.9 3.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Lipase_GDSL_2 PF13472.6 KEY72378.1 - 7.6e-19 68.8 0.4 1.1e-18 68.3 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY72378.1 - 2.5e-09 37.4 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_127 PF07944.12 KEY72379.1 - 1.7e-133 445.9 0.0 1.9e-133 445.7 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Stress-antifung PF01657.17 KEY72379.1 - 0.051 14.2 0.1 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Salt stress response/antifungal DUF4986 PF16375.5 KEY72379.1 - 0.067 13.9 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function Ank_2 PF12796.7 KEY72380.1 - 2.3e-36 124.2 0.0 6.3e-15 55.5 0.0 6.9 4 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY72380.1 - 7.7e-26 87.3 6.9 3.1e-05 24.0 0.0 10.6 10 1 0 10 10 10 3 Ankyrin repeat Ank_4 PF13637.6 KEY72380.1 - 4.2e-25 87.8 1.3 9.3e-08 32.5 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY72380.1 - 7.7e-24 83.0 4.3 8.5e-05 22.8 0.1 9.7 8 2 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KEY72380.1 - 2.9e-20 72.0 3.6 9.2e-06 25.8 0.0 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) DUF3046 PF11248.8 KEY72380.1 - 0.046 14.1 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) F-box-like PF12937.7 KEY72380.1 - 0.078 12.9 0.7 0.27 11.2 0.2 2.3 2 0 0 2 2 2 0 F-box-like Glyco_hydro_43 PF04616.14 KEY72381.1 - 5.1e-10 39.1 1.5 9.2e-10 38.3 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Beta_helix PF13229.6 KEY72382.1 - 5.7e-11 42.5 26.2 9e-10 38.6 10.8 3.0 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 KEY72382.1 - 5.7e-06 25.5 0.2 3.2e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Chondroitinase B DUF1565 PF07602.11 KEY72382.1 - 0.018 14.4 9.3 0.041 13.2 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) Dehydratase_LU PF02286.15 KEY72382.1 - 0.029 13.0 0.1 0.043 12.4 0.1 1.2 1 0 0 1 1 1 0 Dehydratase large subunit SNF2_N PF00176.23 KEY72384.1 - 3.2e-06 26.1 0.0 3.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEY72384.1 - 1.7e-05 24.9 0.0 1.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KEY72384.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KEY72384.1 - 0.028 14.1 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Cwf_Cwc_15 PF04889.12 KEY72385.1 - 0.016 15.0 8.5 0.017 14.9 8.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KEY72385.1 - 0.061 12.6 11.4 0.073 12.4 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KEY72385.1 - 0.32 11.0 5.7 0.37 10.8 5.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF688 PF05097.12 KEY72385.1 - 1 8.4 6.2 1.3 8.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) FAM176 PF14851.6 KEY72385.1 - 1.7 8.3 5.2 2.8 7.6 5.2 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 KEY72385.1 - 6.1 7.3 20.3 83 3.7 20.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 KEY72388.1 - 2.5e-29 102.3 30.2 4.1e-29 101.6 30.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KEY72389.1 - 2.9e-43 148.2 0.0 7.3e-43 146.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KEY72389.1 - 3.8e-20 72.0 0.0 6.6e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KEY72389.1 - 8.8e-15 55.0 2.1 5.6e-14 52.5 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KEY72389.1 - 2.3e-13 50.2 2.9 3.3e-10 40.1 3.3 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 KEY72389.1 - 6e-11 42.2 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KEY72389.1 - 4.6e-09 36.0 0.0 1.2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 KEY72389.1 - 6.9e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain DAO PF01266.24 KEY72389.1 - 1.2e-05 25.0 0.5 0.41 10.2 0.0 4.1 3 2 2 5 5 5 2 FAD dependent oxidoreductase Rubredoxin_C PF18267.1 KEY72389.1 - 0.00015 21.7 0.2 0.63 10.0 0.0 2.6 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KEY72389.1 - 0.00064 19.7 0.1 3.4 7.7 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEY72389.1 - 0.019 14.1 3.2 0.19 10.8 0.0 2.9 1 1 2 3 3 3 0 FAD binding domain TrkA_N PF02254.18 KEY72389.1 - 0.068 13.4 1.0 1.6 9.0 0.3 2.5 2 0 0 2 2 2 0 TrkA-N domain Oxidored_molyb PF00174.19 KEY72390.1 - 1.3e-55 187.7 0.0 2.3e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KEY72390.1 - 2.2e-47 160.5 0.1 3.9e-47 159.7 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KEY72390.1 - 1.1e-30 106.5 0.0 2.9e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEY72390.1 - 7.4e-25 87.2 0.0 1.7e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KEY72390.1 - 8.6e-19 67.5 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KEY72390.1 - 0.0096 16.0 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF1073 PF06381.11 KEY72390.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Peptidase_M6 PF05547.11 KEY72392.1 - 2.3e-08 32.9 0.6 5.1e-05 21.8 0.6 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 bZIP_1 PF00170.21 KEY72393.1 - 8.5e-07 29.0 6.6 1.2e-06 28.5 6.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY72393.1 - 0.00013 21.9 9.0 0.00023 21.2 9.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY72393.1 - 0.00018 21.9 8.3 0.00028 21.3 8.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor FAM199X PF15814.5 KEY72393.1 - 0.45 9.5 3.5 0.61 9.1 3.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF3860 PF12976.7 KEY72394.1 - 0.12 12.4 3.2 0.69 10.0 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) Barttin PF15462.6 KEY72394.1 - 0.36 10.6 5.3 0.14 11.9 0.4 2.3 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pectate_lyase PF03211.13 KEY72395.1 - 1.4e-83 279.5 8.1 2e-83 278.9 8.1 1.3 1 0 0 1 1 1 1 Pectate lyase 4HBT_3 PF13622.6 KEY72396.1 - 5.3e-16 59.6 0.1 1e-15 58.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4449 PF14613.6 KEY72397.1 - 0.0002 21.5 0.1 0.0002 21.5 0.1 2.5 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) NADPH_Ox PF08414.10 KEY72397.1 - 0.11 12.8 0.6 5 7.5 0.1 2.6 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase KinB_sensor PF16767.5 KEY72397.1 - 0.19 12.2 1.3 0.73 10.3 0.1 2.6 2 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1929 PF09118.11 KEY72398.1 - 4.2e-21 75.1 1.9 9e-21 74.0 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KEY72398.1 - 5.7e-18 65.3 1.7 1.4e-17 64.0 0.1 2.5 3 0 0 3 3 3 1 F5/8 type C domain Kelch_6 PF13964.6 KEY72398.1 - 7.6e-17 60.9 1.4 1.6e-06 28.2 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KEY72398.1 - 3.1e-12 45.9 4.0 7.6e-05 22.2 0.3 4.6 3 1 0 3 3 3 3 Kelch motif Glyoxal_oxid_N PF07250.11 KEY72398.1 - 7.2e-10 38.5 0.4 1.4e-05 24.4 0.1 2.8 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KEY72398.1 - 2.9e-09 36.8 10.2 0.00041 20.3 0.0 5.8 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KEY72398.1 - 5e-05 23.1 0.6 0.54 10.3 0.1 4.0 3 1 0 3 3 3 2 Kelch motif RCC1_2 PF13540.6 KEY72398.1 - 0.064 13.1 2.9 2 8.3 0.1 3.7 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Kelch_3 PF13415.6 KEY72398.1 - 0.1 12.9 15.8 15 6.0 0.1 5.8 6 1 0 6 6 6 0 Galactose oxidase, central domain Secretin PF00263.21 KEY72398.1 - 0.18 11.4 0.5 7 6.3 0.1 2.9 3 0 0 3 3 3 0 Bacterial type II and III secretion system protein MFS_1 PF07690.16 KEY72399.1 - 4.9e-34 117.8 19.3 2.3e-27 95.9 4.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72399.1 - 3.5e-12 45.9 0.0 3.5e-12 45.9 0.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KEY72399.1 - 0.00027 19.5 5.1 0.026 12.9 1.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KEY72399.1 - 0.00036 19.5 8.5 0.00079 18.4 3.3 2.3 2 0 0 2 2 2 2 MFS_1 like family Vac7 PF12751.7 KEY72399.1 - 0.009 15.5 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Peptidase_M28 PF04389.17 KEY72401.1 - 3.8e-40 137.7 0.0 5.8e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY72401.1 - 5.5e-09 35.9 0.1 1.2e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY72401.1 - 0.00014 21.6 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short PF00106.25 KEY72402.1 - 4.3e-23 81.8 0.0 2e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72402.1 - 1.8e-14 53.9 0.1 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72402.1 - 8.8e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Phyto-Amp PF15438.6 KEY72402.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma Fungal_trans PF04082.18 KEY72403.1 - 4.1e-07 29.3 0.0 1.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72403.1 - 0.0016 18.5 8.0 0.0031 17.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KEY72404.1 - 1.7e-19 70.3 0.0 3.7e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY72404.1 - 0.0018 17.6 0.6 0.039 13.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY72404.1 - 0.025 14.2 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72404.1 - 0.05 12.8 0.9 0.49 9.6 0.0 2.6 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY72404.1 - 0.061 12.4 0.3 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY72404.1 - 0.061 13.6 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3464 PF11947.8 KEY72404.1 - 0.25 11.1 0.6 0.54 10.0 0.6 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pec_lyase_C PF00544.19 KEY72406.1 - 1.6e-45 155.3 6.2 1.6e-45 155.3 6.2 1.7 2 0 0 2 2 2 1 Pectate lyase Pyr_redox_2 PF07992.14 KEY72407.1 - 1.7e-13 50.5 0.1 4.6e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY72407.1 - 0.0052 16.4 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY72407.1 - 0.026 14.5 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEY72407.1 - 0.1 11.6 0.7 0.22 10.6 0.2 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein Molybdopterin PF00384.22 KEY72408.1 - 1e-68 232.3 0.0 1.5e-68 231.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KEY72408.1 - 2.5e-24 85.5 0.8 4.1e-24 84.7 0.0 1.8 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KEY72408.1 - 2.3e-13 49.9 0.5 6.4e-13 48.5 0.2 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain MoeA_N PF03453.17 KEY72409.1 - 5.1e-33 114.1 0.3 8.1e-33 113.4 0.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KEY72409.1 - 3.9e-27 94.7 0.0 8.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KEY72409.1 - 0.014 15.5 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Glyco_hydro_43 PF04616.14 KEY72410.1 - 1.2e-20 74.1 6.6 3.1e-08 33.3 0.0 3.9 3 1 1 4 4 4 3 Glycosyl hydrolases family 43 MFS_1 PF07690.16 KEY72411.1 - 3.2e-40 138.1 32.3 3.2e-40 138.1 32.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72411.1 - 3.1e-13 49.4 9.4 3.1e-13 49.4 9.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY72411.1 - 1.5e-07 30.3 1.3 2.6e-07 29.5 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_oprn_chp PF09534.10 KEY72411.1 - 0.017 14.9 1.5 0.043 13.6 0.1 2.2 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KEY72411.1 - 5.6 6.9 9.8 18 5.2 0.0 4.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain K_oxygenase PF13434.6 KEY72412.1 - 3.8e-16 59.2 0.0 7.4e-09 35.2 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEY72412.1 - 2.5e-11 43.4 0.0 0.0022 17.3 0.0 3.5 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY72412.1 - 2.2e-09 37.0 0.0 0.00044 19.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY72412.1 - 2e-07 31.0 0.5 5.4e-05 22.9 2.4 2.7 1 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY72412.1 - 0.0002 20.8 1.3 0.0071 15.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEY72412.1 - 0.00029 19.7 0.0 0.042 12.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KEY72412.1 - 0.0029 16.9 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KEY72412.1 - 0.0046 17.0 1.8 0.35 10.8 1.8 2.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY72412.1 - 0.0052 17.0 0.2 0.039 14.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY72412.1 - 0.015 14.4 3.7 0.035 13.2 0.0 2.6 4 0 0 4 4 4 0 FAD binding domain Lycopene_cycl PF05834.12 KEY72412.1 - 0.025 13.7 0.1 0.057 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KEY72412.1 - 0.12 12.9 0.2 17 6.1 0.0 3.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY72412.1 - 0.16 11.0 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TFR_dimer PF04253.15 KEY72413.1 - 8e-24 84.1 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEY72413.1 - 3.3e-19 69.4 0.0 6.8e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY72413.1 - 8.1e-08 32.2 0.1 2.2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 PA domain Glyco_hydro_3 PF00933.21 KEY72414.1 - 1.5e-49 169.1 0.0 2.1e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY72414.1 - 1.9e-08 34.5 0.0 1e-06 28.8 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain SpvB PF03534.13 KEY72414.1 - 0.04 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein DUF1690 PF07956.11 KEY72414.1 - 0.048 14.1 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DJ-1_PfpI PF01965.24 KEY72415.1 - 7.7e-13 48.6 0.0 2.4e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family FAD_binding_4 PF01565.23 KEY72417.1 - 2.9e-18 66.0 0.8 5.3e-18 65.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY72417.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Tyrosinase PF00264.20 KEY72418.1 - 2.7e-45 155.4 0.2 3.8e-45 154.9 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase OmdA PF13376.6 KEY72418.1 - 0.045 13.8 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Hydrophobin_2 PF06766.11 KEY72419.1 - 1.5e-27 95.3 9.7 1.9e-27 95.0 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Na_H_Exchanger PF00999.21 KEY72420.1 - 8.9e-42 143.2 26.6 1.1e-41 143.0 26.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3632 PF12311.8 KEY72421.1 - 0.0057 17.1 0.0 0.0091 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) OHCU_decarbox PF09349.10 KEY72424.1 - 7.1e-43 146.8 0.0 8.4e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.11 KEY72425.1 - 8.4e-32 109.0 3.1 1.9e-31 107.9 3.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KEY72425.1 - 2.6e-13 50.2 0.9 0.012 16.5 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72425.1 - 1.3e-10 41.5 0.0 0.0015 18.8 0.0 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain V_ATPase_I_N PF18670.1 KEY72425.1 - 7.8e-05 23.0 1.5 0.00014 22.2 0.8 1.8 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain HPS3_N PF14761.6 KEY72425.1 - 0.0083 15.7 0.0 1 8.9 0.0 2.6 1 1 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Lactonase PF10282.9 KEY72425.1 - 0.017 14.4 0.0 0.15 11.3 0.0 2.4 1 1 2 3 3 3 0 Lactonase, 7-bladed beta-propeller zf-Nse PF11789.8 KEY72425.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit VID27 PF08553.10 KEY72425.1 - 0.037 13.1 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain U-box PF04564.15 KEY72425.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain Coatomer_WDAD PF04053.14 KEY72425.1 - 0.092 11.8 0.0 0.66 9.0 0.0 1.9 1 1 0 1 1 1 0 Coatomer WD associated region zf-RING_UBOX PF13445.6 KEY72426.1 - 0.00011 22.1 0.2 0.00035 20.5 0.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KEY72426.1 - 0.0016 18.3 1.4 0.032 14.1 0.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEY72426.1 - 0.0083 16.1 4.0 0.033 14.2 4.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEY72426.1 - 0.0094 15.8 0.4 0.0094 15.8 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEY72426.1 - 0.011 15.5 0.3 0.028 14.3 0.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY72426.1 - 0.052 13.9 2.7 0.16 12.4 0.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KEY72426.1 - 0.066 13.1 3.0 0.16 11.8 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY72426.1 - 0.23 11.6 1.5 0.77 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KEY72426.1 - 0.37 11.0 2.9 1.4 9.1 2.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger Aldo_ket_red PF00248.21 KEY72427.1 - 5.9e-32 111.0 0.0 1.3e-22 80.4 0.0 2.8 2 1 1 3 3 3 2 Aldo/keto reductase family TFIIA PF03153.13 KEY72427.1 - 0.11 12.5 32.8 0.054 13.5 20.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eRF1_1 PF03463.15 KEY72428.1 - 2.6e-38 130.9 0.2 9.2e-38 129.2 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 KEY72428.1 - 7.9e-21 74.8 0.1 1.2e-20 74.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KEY72428.1 - 5.8e-15 55.8 0.0 1.1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Gluconate_2-dh3 PF13618.6 KEY72428.1 - 0.031 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 WD40 PF00400.32 KEY72429.1 - 5.3e-23 80.9 4.5 1.1e-06 29.2 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72429.1 - 1.6e-06 28.3 0.1 0.96 9.8 0.0 4.6 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY72429.1 - 5.1e-05 22.4 0.4 0.0081 15.2 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEY72429.1 - 0.011 15.6 0.1 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TF_Zn_Ribbon PF08271.12 KEY72429.1 - 3.1 7.4 4.2 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Thioredoxin PF00085.20 KEY72430.1 - 1.5e-19 69.9 0.0 2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KEY72430.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY72430.1 - 0.00029 21.2 0.1 0.0054 17.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KEY72430.1 - 0.00036 20.0 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KEY72430.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KEY72430.1 - 0.1 13.0 0.0 0.57 10.5 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like WD40 PF00400.32 KEY72431.1 - 1.9e-15 57.0 7.1 1.8e-06 28.6 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KEY72431.1 - 6.1e-14 52.0 0.1 1.9e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KEY72431.1 - 5.9e-08 32.9 1.1 0.0054 17.0 0.1 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KEY72431.1 - 0.025 13.5 1.9 0.036 13.0 0.4 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SBP_bac_11 PF13531.6 KEY72432.1 - 0.028 14.2 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Fungal_trans PF04082.18 KEY72433.1 - 3.5e-13 49.2 0.0 5.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72433.1 - 1.7e-08 34.5 9.6 2.9e-08 33.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MqsR_toxin PF15723.5 KEY72433.1 - 0.047 14.1 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA Lactonase PF10282.9 KEY72434.1 - 1.2e-48 166.2 0.0 1.7e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 KEY72434.1 - 0.025 13.7 0.0 0.055 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Glyco_hydro_16 PF00722.21 KEY72435.1 - 7.1e-44 149.4 0.4 1.1e-43 148.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Trypan_PARP PF05887.11 KEY72435.1 - 0.068 13.1 4.6 0.15 12.1 4.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 KEY72435.1 - 0.099 10.9 5.6 0.14 10.4 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEY72435.1 - 0.12 11.7 12.9 0.23 10.8 12.9 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KEY72435.1 - 0.15 12.1 3.1 0.25 11.4 3.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 KEY72435.1 - 0.17 12.2 10.6 0.34 11.3 10.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 KEY72435.1 - 0.18 11.2 8.4 0.24 10.8 8.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEY72435.1 - 0.46 8.6 8.9 0.57 8.3 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 KEY72435.1 - 0.49 10.1 4.9 0.93 9.2 4.9 1.5 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 KEY72435.1 - 0.87 9.4 6.4 1.4 8.7 6.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KEY72435.1 - 0.91 10.0 17.3 2.3 8.6 17.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Chitin_bind_1 PF00187.19 KEY72435.1 - 1 9.9 11.8 2.3 8.8 11.8 1.6 1 0 0 1 1 1 0 Chitin recognition protein DUF2457 PF10446.9 KEY72435.1 - 2.8 7.0 18.4 3.8 6.5 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 KEY72435.1 - 3.6 7.2 11.7 7 6.3 11.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 KEY72435.1 - 7.6 4.7 6.0 10 4.3 6.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 KEY72435.1 - 8.5 5.6 15.2 11 5.2 15.2 1.1 1 0 0 1 1 1 0 BUD22 DEAD PF00270.29 KEY72436.1 - 6e-38 130.3 0.1 9.9e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY72436.1 - 2.8e-31 108.1 0.8 2.5e-30 105.1 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY72436.1 - 4.3e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KEY72436.1 - 0.0057 15.0 0.3 0.0074 14.6 0.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Myb_DNA-binding PF00249.31 KEY72437.1 - 3e-17 62.5 2.0 3.2e-10 40.0 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY72437.1 - 2.5e-09 37.3 0.8 0.00015 21.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEY72439.1 - 0.00053 20.1 0.2 0.016 15.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ILVD_EDD PF00920.21 KEY72440.1 - 1e-208 694.2 1.7 1.2e-208 694.0 1.7 1.0 1 0 0 1 1 1 1 Dehydratase family PX PF00787.24 KEY72441.1 - 5.8e-19 68.2 0.3 1.1e-18 67.3 0.3 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_L27A PF00828.19 KEY72442.1 - 6.4e-33 114.2 0.2 9.3e-33 113.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_transf_15 PF01793.16 KEY72443.1 - 5e-95 318.5 5.4 2.2e-94 316.4 5.4 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.6 KEY72444.1 - 1.2e-30 107.2 19.7 1.3e-30 107.1 19.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) SRP-alpha_N PF04086.13 KEY72444.1 - 2.5 7.9 13.6 2.9 7.7 13.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal COX5B PF01215.19 KEY72445.1 - 2e-56 189.2 0.0 2.6e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 KEY72445.1 - 0.012 15.4 0.2 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger SnoaL_2 PF12680.7 KEY72446.1 - 0.0055 17.3 0.0 0.011 16.4 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KEY72446.1 - 0.14 12.0 0.1 1.6 8.5 0.1 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Fructosamin_kin PF03881.14 KEY72447.1 - 4.8e-26 91.6 0.0 6.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEY72447.1 - 0.01 15.8 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KEY72448.1 - 3.2e-14 53.3 0.9 4e-07 30.5 0.0 4.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY72448.1 - 4.7e-10 39.8 1.4 0.033 14.8 0.0 6.0 3 3 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY72448.1 - 3.1e-08 33.2 1.9 4.4 8.2 0.0 7.2 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.30 KEY72448.1 - 2.2e-05 24.7 6.4 2.3 8.8 0.0 6.1 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEY72448.1 - 0.0006 20.1 0.1 3 8.3 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY72449.1 - 1.2e-21 77.1 1.1 3.5e-08 33.9 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY72449.1 - 1.4e-19 68.1 10.3 8.9e-05 22.6 0.1 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 KEY72449.1 - 2.4e-15 56.7 1.4 2.3e-06 28.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY72449.1 - 5.3e-13 48.8 7.8 0.0078 16.6 0.2 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KEY72449.1 - 1.6e-11 44.2 2.9 0.01 16.1 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) F-box PF00646.33 KEY72449.1 - 0.0054 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY72449.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like Asp PF00026.23 KEY72450.1 - 3.6e-56 190.9 0.0 4.3e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY72450.1 - 8.9e-15 55.4 0.5 2e-13 50.9 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY72450.1 - 4.1e-05 24.1 0.0 0.004 17.8 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KEY72450.1 - 0.00062 20.3 0.0 0.084 13.5 0.0 2.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Trypan_PARP PF05887.11 KEY72450.1 - 0.042 13.8 3.5 0.073 13.0 3.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Uds1 PF15456.6 KEY72451.1 - 5.4e-26 91.3 6.6 6.2e-26 91.1 6.6 1.0 1 0 0 1 1 1 1 Up-regulated During Septation ZapB PF06005.12 KEY72451.1 - 0.02 15.3 0.5 0.02 15.3 0.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB GvpK PF05121.12 KEY72451.1 - 0.064 13.3 3.2 0.16 12.1 0.5 2.1 2 0 0 2 2 2 0 Gas vesicle protein K Noelin-1 PF12308.8 KEY72451.1 - 0.15 12.1 1.4 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Nucleolin_bd PF16725.5 KEY72451.1 - 0.31 10.7 3.5 0.18 11.5 0.8 2.1 2 1 0 2 2 2 0 Nucleolin binding domain Med22 PF06179.12 KEY72452.1 - 0.00058 20.0 0.0 0.00084 19.5 0.0 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3431 PF11913.8 KEY72453.1 - 6.1e-84 281.1 0.2 1.3e-65 221.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Bestrophin PF01062.21 KEY72454.1 - 3.8e-36 125.0 0.2 6.5e-36 124.2 0.2 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Phage_holin_Dp1 PF16938.5 KEY72454.1 - 0.1 12.8 1.2 0.3 11.3 1.2 1.7 1 0 0 1 1 1 0 Putative phage holin Dp-1 PHO4 PF01384.20 KEY72454.1 - 1.3 8.0 3.7 4.5 6.2 3.7 1.9 1 1 0 1 1 1 0 Phosphate transporter family MFS_1 PF07690.16 KEY72455.1 - 4e-29 101.7 36.4 4e-29 101.7 36.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72455.1 - 5.1e-09 35.5 8.3 5.1e-09 35.5 8.3 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY72455.1 - 0.0004 18.9 1.0 0.00067 18.2 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.7 KEY72456.1 - 3.3e-10 41.0 0.3 4.9e-10 40.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72456.1 - 1.4e-05 24.5 0.1 3.9e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEY72456.1 - 0.012 15.3 1.1 0.056 13.1 1.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lactamase_B_3 PF13483.6 KEY72457.1 - 0.00022 21.1 1.3 0.00036 20.5 1.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KEY72457.1 - 0.00031 20.3 0.2 0.0006 19.4 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 KEY72458.1 - 1e-12 47.9 0.1 3.1e-05 23.4 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY72458.1 - 9.2e-06 25.1 0.3 0.0034 16.7 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY72458.1 - 2.9e-05 24.2 0.0 0.0002 21.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY72458.1 - 0.00011 21.5 0.4 0.0013 17.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEY72458.1 - 0.00015 21.1 0.9 0.00022 20.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEY72458.1 - 0.0017 18.0 1.2 0.0026 17.4 0.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY72458.1 - 0.0025 16.6 0.1 0.0042 15.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KEY72458.1 - 0.0027 16.8 1.2 0.0042 16.2 0.6 1.6 1 1 1 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEY72458.1 - 0.019 14.2 0.2 0.044 13.0 0.2 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KEY72458.1 - 0.14 11.2 0.1 0.27 10.3 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEY72458.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Zn_clus PF00172.18 KEY72460.1 - 8.5e-09 35.4 10.9 1.6e-08 34.5 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY72460.1 - 6.2e-06 25.4 0.2 1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KEY72461.1 - 1.4e-19 70.5 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KEY72461.1 - 0.046 14.0 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Asp PF00026.23 KEY72462.1 - 1.1e-63 215.6 0.6 1.3e-63 215.4 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY72462.1 - 5.6e-08 33.2 1.4 7.8e-06 26.2 0.5 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KEY72462.1 - 0.011 15.5 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal RIO1 PF01163.22 KEY72463.1 - 1.5e-66 223.6 1.1 2.2e-66 223.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KEY72463.1 - 0.0075 15.7 0.2 0.11 11.8 0.2 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY72463.1 - 0.024 14.6 0.1 1.9 8.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 KEY72464.1 - 3.7e-18 65.5 0.5 6e-18 64.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72464.1 - 6.7e-08 32.5 12.6 1.3e-07 31.6 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med6 PF04934.14 KEY72464.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 MED6 mediator sub complex component RdRP PF05183.12 KEY72465.1 - 1.6e-117 393.6 0.0 2.3e-117 393.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Tektin PF03148.14 KEY72465.1 - 0.12 11.1 1.3 0.39 9.4 0.5 1.9 2 0 0 2 2 2 0 Tektin family DUF5446 PF17522.2 KEY72465.1 - 0.47 10.7 1.2 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) peroxidase PF00141.23 KEY72466.1 - 3.7e-28 98.8 0.0 5.6e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4407 PF14362.6 KEY72467.1 - 1.7 7.9 6.4 2.7 7.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cyclin PF08613.11 KEY72468.1 - 1.5e-43 148.9 0.3 1.2e-42 146.0 0.3 2.0 1 1 0 1 1 1 1 Cyclin TPP_enzyme_N PF02776.18 KEY72469.1 - 3e-43 147.4 0.1 4.3e-41 140.4 0.1 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEY72469.1 - 3.7e-18 65.8 1.3 2.5e-17 63.1 0.3 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY72469.1 - 1.2e-12 47.7 0.0 5.9e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.23 KEY72470.1 - 1.3e-15 57.4 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY72470.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Catalase PF00199.19 KEY72471.1 - 4.3e-175 582.4 0.8 5.6e-175 582.0 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KEY72471.1 - 9.8e-19 67.3 0.1 1.9e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KEY72471.1 - 3.5e-11 43.0 0.3 1.1e-10 41.3 0.1 2.0 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KEY72471.1 - 9.7e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family XFP_N PF09364.10 KEY72472.1 - 1.3e-144 481.6 0.0 2.2e-144 480.8 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KEY72472.1 - 2.1e-81 272.2 0.1 3.3e-81 271.6 0.1 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KEY72472.1 - 2.8e-78 261.6 0.1 4.4e-78 261.0 0.1 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KEY72472.1 - 0.0088 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KEY72472.1 - 0.036 14.0 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain UDPG_MGDP_dh PF00984.19 KEY72473.1 - 5.5e-21 74.6 0.0 2.1e-19 69.5 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KEY72473.1 - 5e-14 52.3 0.1 7e-12 45.3 0.1 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KEY72473.1 - 0.00023 21.4 0.0 0.00039 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KEY72473.1 - 0.0084 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KEY72473.1 - 0.16 12.2 0.1 0.46 10.8 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEY72473.1 - 0.18 12.1 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Polysacc_deac_1 PF01522.21 KEY72474.1 - 1.8e-25 89.2 0.0 3.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KEY72474.1 - 8.3e-11 42.2 54.4 3.2e-06 27.5 16.1 3.6 3 1 0 3 3 3 2 Chitin recognition protein DUF2334 PF10096.9 KEY72474.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_synth_2 PF03142.15 KEY72475.1 - 2.6e-42 145.1 1.7 1.5e-31 109.6 1.9 2.2 2 0 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 KEY72475.1 - 5.5e-10 39.3 0.0 0.0005 19.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KEY72475.1 - 2.3e-06 27.7 3.9 2.3e-06 27.7 3.9 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEY72475.1 - 1.8e-05 24.8 0.1 0.049 13.5 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_transf_6 PF03414.13 KEY72475.1 - 0.0026 16.6 0.4 0.0047 15.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 6 Shisa PF13908.6 KEY72476.1 - 0.021 15.1 0.0 0.024 14.9 0.0 1.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMIE PF16038.5 KEY72476.1 - 0.03 14.2 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 TMIE protein Peptidase_M28 PF04389.17 KEY72477.1 - 1.5e-40 139.0 0.0 2.2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY72477.1 - 5.7e-09 35.9 0.1 1.6e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY72477.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PALP PF00291.25 KEY72478.1 - 1.9e-66 224.5 0.1 3.5e-66 223.6 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KEY72478.1 - 9.5e-14 51.6 0.0 9.7e-10 38.8 0.0 2.9 2 0 0 2 2 2 2 CBS domain FLgD_tudor PF13861.6 KEY72478.1 - 0.0029 17.8 0.1 0.33 11.2 0.0 2.4 2 0 0 2 2 2 2 FlgD Tudor-like domain SRPRB PF09439.10 KEY72479.1 - 2.1e-30 105.5 0.0 4.7e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KEY72479.1 - 1.1e-09 38.0 0.0 3.5e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEY72479.1 - 1.3e-06 28.5 0.1 2.4e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEY72479.1 - 7.6e-05 22.3 0.1 0.00039 20.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEY72479.1 - 0.0044 16.4 0.0 0.0081 15.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KEY72479.1 - 0.0048 17.1 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KEY72479.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.4 2 0 0 2 2 2 1 Septin Ras PF00071.22 KEY72479.1 - 0.0084 15.7 0.0 0.022 14.4 0.0 1.7 1 1 0 1 1 1 1 Ras family TniB PF05621.11 KEY72479.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KEY72479.1 - 0.094 12.3 0.6 0.48 10.0 0.1 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KEY72479.1 - 0.14 11.7 0.0 29 4.2 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B DHHC PF01529.20 KEY72480.1 - 7.6e-34 116.7 10.0 7.6e-34 116.7 10.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KEY72480.1 - 7.1e-28 97.0 0.0 2.4e-13 50.5 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY72480.1 - 1.2e-25 89.5 2.3 4.7e-07 30.2 0.2 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY72480.1 - 4.7e-23 81.0 0.2 1.2e-05 25.5 0.0 4.8 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY72480.1 - 6.5e-23 80.1 0.7 1.2e-05 25.5 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KEY72480.1 - 1.4e-22 77.4 2.0 2.1e-07 30.7 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat DUF2304 PF10066.9 KEY72480.1 - 0.3 11.3 3.9 3.8 7.8 1.7 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pyr_redox_3 PF13738.6 KEY72482.1 - 1.3e-17 64.0 0.0 1.7e-15 57.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY72482.1 - 2e-14 53.5 0.0 1.5e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY72482.1 - 5.8e-13 48.1 0.0 7.6e-12 44.4 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEY72482.1 - 1.3e-10 41.0 0.0 1.1e-07 31.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KEY72482.1 - 1.7e-06 28.5 1.4 0.059 13.9 0.6 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY72482.1 - 2.9e-06 27.4 0.1 2.9e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KEY72482.1 - 0.00011 21.5 1.5 0.024 13.9 0.2 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KEY72482.1 - 0.00027 20.6 2.1 0.00027 20.6 2.1 2.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEY72482.1 - 0.00072 19.5 0.5 0.0013 18.7 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KEY72482.1 - 0.00077 18.7 1.8 0.0014 17.8 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEY72482.1 - 0.0023 17.9 2.2 0.058 13.4 0.1 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KEY72482.1 - 0.0065 16.5 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KEY72482.1 - 0.016 14.3 1.0 0.016 14.3 1.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 KEY72482.1 - 0.037 12.7 0.5 0.037 12.7 0.5 2.0 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KEY72482.1 - 0.15 11.4 0.1 15 4.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KEY72482.1 - 0.18 11.0 0.1 0.53 9.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KEY72482.1 - 0.29 10.4 0.8 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HAUS-augmin3 PF14932.6 KEY72483.1 - 0.00068 19.3 9.0 0.00068 19.3 9.0 2.8 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 MHC_II_beta PF00969.19 KEY72483.1 - 0.077 13.1 0.2 0.29 11.3 0.2 2.0 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DDE_Tnp_IS1595 PF12762.7 KEY72483.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain Med9 PF07544.13 KEY72483.1 - 0.25 11.5 3.9 36 4.5 1.8 3.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF5082 PF16888.5 KEY72483.1 - 0.41 10.9 6.0 0.34 11.2 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CdvA PF18822.1 KEY72483.1 - 0.57 10.0 10.4 0.24 11.2 1.5 3.1 2 1 1 3 3 3 0 CdvA-like coiled-coil domain COMMD1_N PF17221.3 KEY72483.1 - 0.7 10.2 4.1 0.89 9.9 0.2 2.7 2 1 0 2 2 2 0 COMMD1 N-terminal domain Prefoldin PF02996.17 KEY72483.1 - 0.7 9.8 6.4 5.4 7.0 2.0 3.7 3 1 1 4 4 4 0 Prefoldin subunit Atg14 PF10186.9 KEY72483.1 - 0.72 8.9 5.4 1.8 7.6 5.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KEY72483.1 - 0.89 9.9 10.2 0.082 13.2 1.2 3.5 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CpG_bind_C PF12269.8 KEY72483.1 - 2.9 7.6 5.5 2 8.2 3.4 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF1664 PF07889.12 KEY72483.1 - 3.5 7.7 7.4 19 5.3 0.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Hrs_helical PF12210.8 KEY72483.1 - 8.4 7.0 15.2 16 6.1 4.6 3.9 4 0 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF16 PF01519.16 KEY72483.1 - 9.9 6.7 14.7 7.3 7.1 1.0 4.0 4 1 1 5 5 3 0 Protein of unknown function DUF16 LrgB PF04172.16 KEY72484.1 - 1.2e-21 77.2 13.1 6.2e-14 52.0 3.8 2.5 2 0 0 2 2 2 2 LrgB-like family Rotamase PF00639.21 KEY72485.1 - 7.7e-24 84.5 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KEY72485.1 - 5.8e-16 59.1 0.0 7.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KEY72485.1 - 2e-07 31.0 1.3 3.1e-07 30.4 0.4 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KEY72485.1 - 6.6e-05 23.7 0.0 7.2e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KEY72485.1 - 0.033 13.9 0.2 0.064 13.0 0.2 1.5 1 0 0 1 1 1 0 WW domain RNA_POL_M_15KD PF02150.16 KEY72486.1 - 4.9e-11 42.3 3.4 4.9e-11 42.3 3.4 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KEY72486.1 - 7.3e-08 32.1 8.4 1.4e-07 31.2 0.1 3.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Ribosomal_L14 PF00238.19 KEY72487.1 - 6.2e-46 155.5 2.5 7.2e-46 155.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.16 KEY72487.1 - 0.016 14.8 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein PI-PLC-C1 PF16670.5 KEY72488.1 - 3.5e-122 407.6 0.0 7.1e-122 406.6 0.0 1.5 2 0 0 2 2 2 1 Phosphoinositide phospholipase C, Ca2+-dependent SET PF00856.28 KEY72488.1 - 1.7e-10 41.6 0.0 7.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 SET domain FAM76 PF16046.5 KEY72488.1 - 0.025 14.0 1.4 0.065 12.6 1.4 1.7 1 0 0 1 1 1 0 FAM76 protein MCCD1 PF15707.5 KEY72488.1 - 0.065 13.7 0.1 0.23 11.9 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Tmemb_55A PF09788.9 KEY72488.1 - 0.078 12.1 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A Serglycin PF04360.12 KEY72488.1 - 0.089 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Serglycin Peptidase_M28 PF04389.17 KEY72489.1 - 7.7e-39 133.4 0.0 1.3e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY72489.1 - 5.2e-11 42.4 0.4 4.1e-10 39.6 0.3 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KEY72489.1 - 0.00015 21.6 0.3 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KEY72489.1 - 0.0036 16.8 0.4 0.079 12.4 0.1 2.2 2 0 0 2 2 2 1 Nicastrin Trimer_CC PF08954.11 KEY72490.1 - 0.11 12.0 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 Trimerisation motif BTB PF00651.31 KEY72491.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Glyoxalase_3 PF13468.6 KEY72492.1 - 4.5e-23 82.3 0.1 6.8e-23 81.7 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain DUF1993 PF09351.10 KEY72493.1 - 4.5e-47 160.2 0.0 5.1e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Sec23_trunk PF04811.15 KEY72493.1 - 0.048 13.2 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Orbi_NS3 PF01616.16 KEY72493.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 2 0 0 2 2 2 0 Orbivirus NS3 Ldh_2 PF02615.14 KEY72494.1 - 6e-122 406.9 1.1 8.3e-122 406.5 1.1 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NicO PF03824.16 KEY72494.1 - 2e-67 227.5 5.7 2e-67 227.5 5.7 2.1 2 0 0 2 2 2 1 High-affinity nickel-transport protein 4HBT PF03061.22 KEY72494.1 - 3.1e-13 49.9 0.7 8.5e-13 48.5 0.7 1.8 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KEY72494.1 - 0.0031 17.8 0.4 0.0057 17.0 0.4 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 KEY72494.1 - 0.068 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) HNH_2 PF13391.6 KEY72495.1 - 0.1 12.7 0.9 8.5 6.6 0.4 2.8 2 0 0 2 2 2 0 HNH endonuclease Peptidase_C2 PF00648.21 KEY72496.1 - 1.7e-59 201.3 0.5 4.1e-58 196.8 0.5 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease APG17 PF04108.12 KEY72498.1 - 2.4e-125 418.8 6.5 2.8e-125 418.5 6.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Bacillus_HBL PF05791.11 KEY72498.1 - 0.018 14.8 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YpsA PF06908.11 KEY72498.1 - 0.18 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 YspA SLOG family Choline_transpo PF04515.12 KEY72499.1 - 3.1e-81 273.1 19.6 3.1e-81 273.1 19.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KEY72499.1 - 0.11 13.1 5.4 0.29 11.8 5.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AMP-binding PF00501.28 KEY72500.1 - 6.4e-74 249.0 0.0 1.2e-73 248.2 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KEY72500.1 - 7.5e-62 208.8 0.0 4.3e-61 206.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KEY72500.1 - 3e-51 173.7 2.2 3e-51 173.7 2.2 2.3 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72500.1 - 2.6e-38 131.9 3.2 6.2e-38 130.7 3.2 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY72500.1 - 3.1e-18 66.1 0.5 3.3e-11 43.1 0.0 3.3 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY72500.1 - 1.7e-16 60.6 2.2 2.9e-13 50.1 1.7 2.4 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 KEY72500.1 - 3.7e-10 40.0 0.0 8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KEY72500.1 - 1.3e-06 27.6 0.0 0.0028 16.7 0.0 3.2 4 0 0 4 4 4 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEY72500.1 - 2.2e-06 27.0 0.4 0.00092 18.4 0.0 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEY72500.1 - 6.1e-06 25.6 0.9 0.012 14.8 0.2 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEY72500.1 - 7.9e-05 22.6 0.8 0.00081 19.3 0.9 2.6 3 0 0 3 3 3 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEY72500.1 - 0.00029 20.3 0.0 0.95 8.8 0.0 2.7 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KEY72500.1 - 0.11 11.8 0.5 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KEY72500.1 - 0.34 10.4 1.1 21 4.6 1.5 2.7 2 0 0 2 2 2 0 NmrA-like family LPMO_10 PF03067.15 KEY72501.1 - 4.8e-13 50.2 0.0 4.8e-13 50.2 0.0 2.4 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Arylsulfotran_2 PF14269.6 KEY72502.1 - 2.1e-54 184.9 1.3 2.8e-54 184.5 1.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEY72502.1 - 1.5e-16 60.3 0.1 3.6e-16 59.1 0.1 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SoxY PF13501.6 KEY72502.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY OPT PF03169.15 KEY72503.1 - 1.7e-150 502.7 52.7 1.9e-150 502.5 52.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Flp1_like PF16982.5 KEY72503.1 - 0.23 10.9 1.9 0.39 10.1 0.2 2.2 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain ABC_tran PF00005.27 KEY72505.1 - 1.5e-43 148.6 0.0 5e-28 98.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY72505.1 - 2.6e-25 89.6 19.3 7.4e-18 65.2 4.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY72505.1 - 6.1e-15 55.3 0.0 5.2e-06 26.1 0.0 3.9 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY72505.1 - 2.3e-06 28.1 0.6 0.0075 16.7 0.2 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY72505.1 - 1.2e-05 25.0 0.2 0.17 11.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY72505.1 - 1.9e-05 24.6 0.1 0.047 13.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KEY72505.1 - 0.00037 20.7 0.7 0.00083 19.5 0.1 1.9 2 0 0 2 2 1 1 Helicase HerA, central domain Dynamin_N PF00350.23 KEY72505.1 - 0.0014 18.7 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 KEY72505.1 - 0.0014 17.9 0.5 0.7 9.1 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin T2SSE PF00437.20 KEY72505.1 - 0.0015 17.7 0.0 1.7 7.6 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KEY72505.1 - 0.0019 18.5 0.5 1.3 9.3 0.4 3.3 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KEY72505.1 - 0.0041 17.7 2.2 0.18 12.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KEY72505.1 - 0.0042 16.7 0.6 0.77 9.3 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KEY72505.1 - 0.0049 16.9 0.2 0.68 10.0 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KEY72505.1 - 0.005 16.7 4.0 0.54 10.0 0.0 3.8 4 1 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KEY72505.1 - 0.0067 15.8 0.0 0.093 12.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family CLP1_P PF16575.5 KEY72505.1 - 0.051 13.4 0.4 12 5.7 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DEAD PF00270.29 KEY72505.1 - 0.079 12.7 0.0 1.9 8.2 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KEY72505.1 - 0.11 12.7 0.0 5.9 7.2 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIG1 PF04548.16 KEY72505.1 - 1.2 8.5 3.9 3.9 6.8 0.0 3.1 4 0 0 4 4 4 0 AIG1 family SNARE PF05739.19 KEY72505.1 - 4.4 7.4 0.0 4.4 7.4 0.0 3.9 4 0 0 4 4 2 0 SNARE domain AA_permease PF00324.21 KEY72506.1 - 9.1e-117 390.6 40.9 1.1e-116 390.3 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY72506.1 - 5.8e-21 74.8 44.7 7.7e-21 74.4 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 KEY72507.1 - 2.4e-26 92.8 0.0 4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 KEY72510.1 - 1.7e-25 89.0 2.8 6e-11 42.6 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY72510.1 - 1.2e-23 83.5 6.5 9.9e-14 51.7 0.3 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEY72510.1 - 2.9e-11 43.3 4.2 0.00038 20.8 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KEY72510.1 - 1.5e-10 40.4 0.1 0.011 16.2 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEY72510.1 - 3.5e-10 39.9 0.4 7.3e-05 23.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) IBR PF01485.21 KEY72511.1 - 3.9e-09 36.6 32.4 0.0015 18.7 1.3 5.1 3 2 0 3 3 3 3 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 KEY72511.1 - 0.0017 18.4 12.1 2.3 8.4 0.2 5.2 5 0 0 5 5 5 2 Zinc ribbon domain Sgf11 PF08209.11 KEY72511.1 - 0.011 15.3 0.2 0.011 15.3 0.2 3.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 KEY72511.1 - 0.033 14.4 5.5 6.4 7.1 0.2 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain Ribosomal_L32p PF01783.23 KEY72511.1 - 0.22 11.8 5.3 11 6.3 0.1 3.6 3 0 0 3 3 3 0 Ribosomal L32p protein family YhfH PF14149.6 KEY72511.1 - 2.4 8.2 13.7 2.4 8.2 4.6 3.5 3 0 0 3 3 3 0 YhfH-like protein DNA_RNApol_7kD PF03604.13 KEY72511.1 - 2.4 7.9 9.3 3.7 7.3 0.3 3.8 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 KEY72511.1 - 9.5 6.1 16.9 0.3 10.9 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEY72512.1 - 0.01 16.0 0.4 0.023 14.8 0.1 1.7 2 0 0 2 2 2 1 Zinc ribbon domain zf-RING_7 PF02591.15 KEY72512.1 - 0.053 13.7 0.2 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain Rx_N PF18052.1 KEY72512.1 - 0.15 12.3 0.1 0.22 11.8 0.1 1.2 1 0 0 1 1 1 0 Rx N-terminal domain TetR_C_19 PF17924.1 KEY72513.1 - 0.076 13.6 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain eIF-5a PF01287.20 KEY72514.1 - 0.17 12.0 0.2 0.33 11.1 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HET PF06985.11 KEY72515.1 - 3.1e-29 102.2 0.4 6.5e-29 101.2 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4314 PF14192.6 KEY72515.1 - 0.093 12.7 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) MFS_1 PF07690.16 KEY72516.1 - 2.9e-20 72.5 57.8 1.2e-13 50.8 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72517.1 - 6.1e-130 434.1 24.7 7e-130 433.9 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72517.1 - 3.2e-23 82.2 37.7 2.6e-15 56.2 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 KEY72517.1 - 0.0071 16.5 3.1 0.0071 16.5 3.1 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF3792) Glyco_transf_20 PF00982.21 KEY72518.1 - 1.9e-150 501.6 0.0 2.6e-150 501.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KEY72518.1 - 4.4e-67 225.6 0.0 8.2e-67 224.7 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Zn_clus PF00172.18 KEY72519.1 - 5.8e-09 35.9 8.7 1e-08 35.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY72519.1 - 8.2e-05 21.8 0.1 0.00023 20.3 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KEY72521.1 - 2.7e-07 30.4 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family WD40 PF00400.32 KEY72523.1 - 9.3e-54 178.2 15.3 2.2e-08 34.6 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72523.1 - 2.4e-19 69.4 0.0 0.00067 19.9 0.0 6.2 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEY72523.1 - 8.2e-08 32.4 0.0 0.00022 21.2 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEY72523.1 - 2e-07 30.1 1.0 0.05 12.2 0.2 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEY72523.1 - 0.00032 19.8 0.1 11 4.9 0.0 4.5 1 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY72523.1 - 0.0022 17.4 0.0 0.21 10.9 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 KEY72523.1 - 0.0066 15.2 0.1 9.9 4.8 0.0 3.8 2 2 1 3 3 3 1 Nup133 N terminal like DUF1513 PF07433.11 KEY72523.1 - 0.011 14.8 1.6 9.9 5.1 0.0 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) Frtz PF11768.8 KEY72523.1 - 0.03 12.7 0.0 0.64 8.3 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KEY72523.1 - 0.11 11.5 0.0 1.6 7.7 0.0 2.5 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Apt1 PF10351.9 KEY72523.1 - 1.9 7.2 11.3 2.5 6.8 11.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 KEY72523.1 - 3.5 7.6 12.4 5.7 6.9 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) GPI-anchored PF10342.9 KEY72524.1 - 4.5e-20 72.2 0.1 4.5e-20 72.2 0.1 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KEY72524.1 - 0.00029 20.7 0.1 0.0093 15.8 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Hamartin PF04388.12 KEY72524.1 - 4.3 5.9 8.9 4.4 5.8 8.9 1.1 1 0 0 1 1 1 0 Hamartin protein THF_DHG_CYH PF00763.23 KEY72525.1 - 1.3e-25 90.0 0.1 1.9e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KEY72525.1 - 2.5e-14 52.9 0.0 1.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Apq12 PF12716.7 KEY72527.1 - 8.1e-11 41.7 18.5 1.5e-10 40.8 18.5 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF716 PF04819.12 KEY72527.1 - 0.11 12.1 6.8 0.15 11.7 6.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) ATP_bind_1 PF03029.17 KEY72528.1 - 1.7e-71 240.8 0.0 4.5e-71 239.4 0.0 1.7 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KEY72528.1 - 0.00082 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KEY72528.1 - 0.0012 19.1 0.5 0.061 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KEY72528.1 - 0.0032 17.5 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEY72528.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEY72528.1 - 0.0079 16.7 0.3 0.07 13.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KEY72528.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KEY72528.1 - 0.018 15.2 0.2 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KEY72528.1 - 0.024 14.7 0.0 0.025 14.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KEY72528.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEY72528.1 - 0.065 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KEY72528.1 - 0.071 12.6 0.1 20 4.6 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY72528.1 - 0.095 12.6 0.1 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_10 PF12846.7 KEY72528.1 - 0.13 11.1 0.0 0.53 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.6 KEY72528.1 - 0.15 12.5 1.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEY72528.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.2 3 1 0 4 4 4 0 AAA ATPase domain S-AdoMet_synt_C PF02773.16 KEY72529.1 - 3.1e-66 221.6 0.0 6e-66 220.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KEY72529.1 - 4.8e-45 152.7 0.0 8.8e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KEY72529.1 - 3.1e-43 146.5 0.4 1.2e-42 144.6 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.9 KEY72529.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) AdoMet_Synthase PF01941.19 KEY72529.1 - 0.14 10.9 0.2 0.56 8.9 0.1 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PI-PLC-X PF00388.19 KEY72531.1 - 1.6e-11 44.0 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MaoC_dehydratas PF01575.19 KEY72534.1 - 3.8e-22 78.2 0.0 6.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KEY72534.1 - 9.1e-05 22.6 0.0 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ERp29_N PF07912.13 KEY72534.1 - 0.14 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain CAP_GLY PF01302.25 KEY72535.1 - 3.3e-19 68.7 0.0 5.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 KEY72535.1 - 2e-12 46.7 7.9 0.00086 19.0 2.3 5.5 4 1 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 KEY72535.1 - 5.9e-12 45.6 6.5 0.021 15.3 0.0 5.6 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEY72535.1 - 3.8e-08 33.0 0.2 0.026 14.0 0.0 3.8 3 1 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KEY72535.1 - 4.6e-06 26.3 6.6 0.83 9.9 0.0 6.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 KEY72535.1 - 5.9e-05 23.1 2.3 55 4.9 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat Aldo_ket_red PF00248.21 KEY72536.1 - 4.3e-56 190.3 0.0 4.9e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KEY72537.1 - 1e-07 32.5 8.3 0.29 12.1 0.9 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ATP-synt_E PF05680.12 KEY72538.1 - 9.1e-24 83.6 0.1 9.8e-24 83.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain STT3 PF02516.14 KEY72539.1 - 5.9e-143 477.3 33.9 6.2e-138 460.8 32.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pkinase PF00069.25 KEY72541.1 - 9.5e-60 202.2 0.0 2.2e-59 201.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72541.1 - 1.2e-28 100.1 0.0 2.2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEY72541.1 - 3e-09 37.1 0.0 7.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEY72541.1 - 0.00058 20.1 0.0 0.0021 18.4 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KEY72541.1 - 0.048 13.0 0.0 0.28 10.5 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 KEY72541.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 KEY72542.1 - 6.3e-07 29.9 1.1 2e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 KEY72542.1 - 0.0029 17.9 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_S9_N PF02897.15 KEY72542.1 - 0.019 13.8 0.1 0.029 13.2 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF2406 PF10295.9 KEY72542.1 - 0.28 11.9 3.9 16 6.3 2.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) SpoIIE PF07228.12 KEY72543.1 - 0.0027 17.7 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEY72543.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Fcf1 PF04900.12 KEY72544.1 - 1.4e-30 105.6 0.1 2.2e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Fcf1 Sigma_reg_N PF13800.6 KEY72544.1 - 0.038 14.3 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CDC45 PF02724.14 KEY72544.1 - 0.14 10.4 5.3 0.19 10.0 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF726 PF05277.12 KEY72545.1 - 1.2e-126 422.3 2.3 1.6e-126 421.9 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MarC PF01914.17 KEY72546.1 - 0.13 11.7 0.5 0.24 10.8 0.3 1.5 1 1 0 1 1 1 0 MarC family integral membrane protein VSP PF03302.13 KEY72547.1 - 2.2e-05 23.5 0.0 3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.12 KEY72547.1 - 0.00024 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 KEY72547.1 - 0.0014 18.8 3.1 0.0014 18.8 3.1 2.0 2 1 0 2 2 2 1 Podoplanin RIFIN PF02009.16 KEY72547.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 KEY72547.1 - 0.0048 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 KEY72547.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KEY72547.1 - 0.046 13.6 0.5 0.082 12.8 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain PIRT PF15099.6 KEY72547.1 - 0.047 13.3 0.2 0.085 12.4 0.1 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Stevor PF17410.2 KEY72547.1 - 0.055 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 KEY72547.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) CcmH PF03918.14 KEY72547.1 - 0.15 11.4 0.0 6.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein YajC PF02699.15 KEY72547.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit YebO PF13974.6 KEY72547.1 - 0.15 12.1 0.2 0.42 10.7 0.2 1.8 1 0 0 1 1 1 0 YebO-like protein EphA2_TM PF14575.6 KEY72547.1 - 0.16 12.8 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 KEY72547.1 - 0.57 10.8 13.0 0.088 13.4 7.4 2.5 2 1 1 3 3 3 0 Small Novel Rich in Cartilage SSP160 PF06933.11 KEY72547.1 - 1.1 7.3 10.2 1.6 6.9 10.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SKG6 PF08693.10 KEY72547.1 - 7.3 6.1 8.9 0.36 10.3 2.5 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF846 PF05832.12 KEY72548.1 - 5.6e-51 172.2 10.7 6.7e-51 172.0 10.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 KEY72548.1 - 0.9 8.8 12.7 0.44 9.9 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) TctB PF07331.11 KEY72548.1 - 1.2 9.4 14.2 2.8 8.2 1.5 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family HpcH_HpaI PF03328.14 KEY72549.1 - 2.7e-44 150.9 0.1 1.4e-43 148.7 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEY72549.1 - 1.2e-11 44.4 0.0 1.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1045 PF06299.12 KEY72549.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Robl_LC7 PF03259.17 KEY72549.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Roadblock/LC7 domain CDC45 PF02724.14 KEY72550.1 - 0.72 8.1 6.3 1 7.5 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 KEY72551.1 - 5.6e-22 77.3 0.0 7.3e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY72551.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KEY72551.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif ChaC PF04752.12 KEY72552.1 - 2.1e-53 181.0 0.0 2.5e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 KEY72553.1 - 3.6e-26 88.7 3.1 1.1e-06 27.8 0.1 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KEY72553.1 - 9.6e-23 80.4 3.1 1.5e-09 38.2 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KEY72553.1 - 2e-21 74.0 2.5 0.0017 18.1 0.3 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KEY72553.1 - 1.5e-19 69.5 5.4 7.3e-10 38.5 0.0 4.8 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KEY72553.1 - 1.5e-17 62.2 0.6 0.0011 18.3 0.0 4.4 4 0 0 4 4 4 4 EF hand Hep_59 PF07052.11 KEY72555.1 - 4.6e-07 30.5 0.0 4.6e-07 30.5 0.0 2.5 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Acylphosphatase PF00708.18 KEY72556.1 - 1.7e-21 76.4 1.7 1.9e-21 76.3 1.7 1.0 1 0 0 1 1 1 1 Acylphosphatase HA2 PF04408.23 KEY72557.1 - 1.7e-22 79.7 0.0 1.7e-22 79.7 0.0 3.6 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY72557.1 - 1.7e-19 69.9 0.0 5.4e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEY72557.1 - 5.1e-14 52.6 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY72557.1 - 1.6e-07 31.2 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY72557.1 - 3.5e-06 27.3 0.1 1.5e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KEY72557.1 - 5.4e-05 22.6 0.0 0.00015 21.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KEY72557.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KEY72557.1 - 0.0019 18.2 0.0 0.61 10.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KEY72557.1 - 0.0024 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY72557.1 - 0.0028 17.4 0.0 0.0085 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEY72557.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KEY72557.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEY72557.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KEY72557.1 - 0.025 14.6 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain GAD PF02938.14 KEY72557.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 GAD domain PhoH PF02562.16 KEY72557.1 - 0.061 12.8 0.1 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KEY72557.1 - 0.072 13.1 0.2 0.37 10.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY72557.1 - 0.073 13.6 0.3 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Microtub_bd PF16796.5 KEY72557.1 - 0.24 11.4 1.3 2.1 8.3 0.5 2.5 2 1 0 2 2 2 0 Microtubule binding WD40 PF00400.32 KEY72558.1 - 3.4e-13 49.8 12.3 0.002 18.9 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72558.1 - 1.1e-05 25.6 0.6 0.017 15.4 0.1 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEY72558.1 - 5e-05 22.2 3.4 8.9e-05 21.3 1.0 2.3 1 1 1 3 3 3 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEY72558.1 - 0.13 11.1 0.5 2.3 7.1 0.3 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Macoilin PF09726.9 KEY72559.1 - 3.4 6.1 8.1 4.1 5.9 8.1 1.3 1 0 0 1 1 1 0 Macoilin family Terpene_synth_C PF03936.16 KEY72560.1 - 0.0032 16.9 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Polysacc_deac_1 PF01522.21 KEY72561.1 - 5e-21 74.9 0.0 8.2e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase OppC_N PF12911.7 KEY72561.1 - 0.039 13.9 2.0 0.042 13.8 0.3 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Polysacc_deac_2 PF04748.13 KEY72561.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase RP854 PF17460.2 KEY72561.1 - 0.073 12.8 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 Terminase_GpA PF05876.12 KEY72561.1 - 0.075 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cys_Met_Meta_PP PF01053.20 KEY72563.1 - 2.9e-57 193.9 0.0 9.6e-57 192.2 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEY72563.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V GspL_C PF12693.7 KEY72565.1 - 0.00095 19.0 0.2 0.0017 18.2 0.2 1.4 1 0 0 1 1 1 1 GspL periplasmic domain LSM PF01423.22 KEY72566.1 - 2.7e-20 71.8 0.2 3.1e-20 71.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEY72566.1 - 0.00018 21.6 0.1 0.00022 21.3 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KEY72566.1 - 0.0004 20.4 0.2 0.00046 20.2 0.2 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Rad60-SLD PF11976.8 KEY72567.1 - 1.8e-16 59.7 0.1 3.8e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEY72567.1 - 2.6e-05 23.9 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TmoB PF06234.12 KEY72567.1 - 0.003 17.6 0.5 0.013 15.6 0.1 2.3 2 0 0 2 2 2 1 Toluene-4-monooxygenase system protein B (TmoB) SIR2 PF02146.17 KEY72568.1 - 4.4e-25 88.6 0.0 1.1e-16 61.3 0.0 2.3 2 0 0 2 2 2 2 Sir2 family GATase_6 PF13522.6 KEY72569.1 - 4.4e-12 46.4 0.0 9.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEY72569.1 - 4.4e-08 33.1 0.0 7.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KEY72569.1 - 3.3e-06 26.7 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ADK PF00406.22 KEY72570.1 - 1.2e-17 64.4 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEY72570.1 - 6.8e-12 46.0 0.0 2.1e-11 44.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY72570.1 - 2.1e-10 41.2 0.0 9.2e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEY72570.1 - 2.2e-05 24.7 0.0 0.00062 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KEY72570.1 - 0.013 15.2 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KEY72570.1 - 0.065 12.5 0.0 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KEY72570.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KEY72570.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY72570.1 - 0.16 12.2 0.0 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Radical_SAM PF04055.21 KEY72571.1 - 2.9e-16 60.3 1.4 3.8e-16 59.9 0.9 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEY72571.1 - 1.7e-06 28.3 0.6 5.1e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEY72571.1 - 3.2e-06 27.2 0.1 6.8e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain CYTH PF01928.21 KEY72572.1 - 2.5e-08 34.1 0.2 6.1e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 CYTH domain Rhomboid PF01694.22 KEY72573.1 - 5.8e-20 71.8 12.3 5.8e-20 71.8 12.3 1.8 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KEY72573.1 - 0.017 14.9 2.0 0.074 12.8 2.0 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Pex14_N PF04695.13 KEY72573.1 - 0.036 14.7 4.6 0.2 12.3 1.0 3.3 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Metal_resist PF13801.6 KEY72573.1 - 0.3 11.3 15.1 3.1 8.0 0.4 3.7 3 1 0 3 3 3 0 Heavy-metal resistance DUF4746 PF15928.5 KEY72574.1 - 0.12 11.8 0.4 0.15 11.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) IU_nuc_hydro PF01156.19 KEY72577.1 - 1.9e-57 195.2 0.0 3.2e-57 194.4 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 KEY72578.1 - 1.5e-16 59.8 0.0 2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain WD40 PF00400.32 KEY72579.1 - 8.5e-41 137.2 22.7 6.7e-09 36.2 1.5 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY72579.1 - 2.8e-16 59.6 1.2 0.028 14.7 0.1 5.8 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KEY72579.1 - 4.9e-15 54.8 3.5 1.5e-14 53.3 3.5 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Cyclin_N PF00134.23 KEY72579.1 - 3.6e-10 39.7 0.0 7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF2A PF08662.11 KEY72579.1 - 0.012 15.5 0.0 4.2 7.2 0.0 3.8 3 1 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KEY72579.1 - 0.024 14.0 0.2 0.67 9.2 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MAM33 PF02330.16 KEY72579.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial glycoprotein WD40_like PF17005.5 KEY72579.1 - 0.11 11.8 0.0 13 5.0 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain Pkinase PF00069.25 KEY72580.1 - 1.8e-67 227.5 0.0 2.2e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72580.1 - 3.3e-30 105.2 0.0 4.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY72580.1 - 0.017 14.1 0.2 0.025 13.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KEY72580.1 - 0.02 14.2 0.0 0.054 12.8 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KEY72580.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 KEY72580.1 - 0.09 13.5 0.1 0.22 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 KEY72580.1 - 0.2 11.6 0.6 3 7.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIF1 PF05970.14 KEY72581.1 - 1.1e-34 120.3 0.0 4.8e-24 85.2 0.0 2.5 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KEY72581.1 - 1.7e-15 57.3 0.0 6.7e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEY72581.1 - 3.1e-10 40.6 0.0 1.3e-09 38.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KEY72581.1 - 1.2e-05 25.0 0.0 4.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KEY72581.1 - 2.1e-05 22.7 0.0 0.00016 19.8 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KEY72581.1 - 0.00018 21.8 0.0 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEY72581.1 - 0.00045 20.6 0.0 0.0035 17.7 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KEY72581.1 - 0.0026 17.8 0.0 0.0074 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KEY72581.1 - 0.0046 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KEY72581.1 - 0.0089 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KEY72581.1 - 0.0099 15.6 0.1 3.3 7.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KEY72581.1 - 0.01 15.8 0.0 0.038 13.9 0.0 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KEY72581.1 - 0.02 15.3 0.0 0.07 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KEY72581.1 - 0.048 12.8 0.1 0.091 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KEY72581.1 - 0.069 13.7 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KEY72581.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KEY72581.1 - 0.14 12.2 0.1 1.4 9.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain TSC22 PF01166.18 KEY72584.1 - 0.039 14.3 0.3 0.077 13.3 0.1 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KEY72584.1 - 0.064 13.4 0.1 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 bZIP transcription factor Mto2_bdg PF12808.7 KEY72584.1 - 0.074 13.4 0.8 0.12 12.7 0.1 1.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PRA1 PF03208.19 KEY72585.1 - 1.2e-19 70.4 0.3 1.2e-19 70.4 0.3 1.5 2 0 0 2 2 2 1 PRA1 family protein rve PF00665.26 KEY72586.1 - 1.9e-06 28.1 0.0 4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Ank_2 PF12796.7 KEY72587.1 - 5.1e-23 81.5 0.0 2.1e-07 31.5 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY72587.1 - 3.5e-16 59.3 0.3 3e-05 24.5 0.0 5.5 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY72587.1 - 1e-14 53.2 8.3 0.054 14.1 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KEY72587.1 - 1.3e-10 41.3 0.8 0.00068 19.9 0.0 5.8 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY72587.1 - 7.2e-06 26.2 4.6 2.9 8.5 0.1 5.4 4 1 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 KEY72587.1 - 0.22 11.5 0.0 0.86 9.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) DNA_ligase_A_M PF01068.21 KEY72588.1 - 3.4e-24 85.6 0.0 5.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEY72588.1 - 6.8e-16 59.1 0.0 1.5e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KEY72588.1 - 0.00028 21.3 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase PNP_UDP_1 PF01048.20 KEY72590.1 - 0.029 13.6 0.5 0.031 13.5 0.5 1.0 1 0 0 1 1 1 0 Phosphorylase superfamily Fungal_trans PF04082.18 KEY72592.1 - 1e-11 44.4 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72592.1 - 4e-07 30.0 7.7 7.9e-07 29.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ofd1_CTDD PF10637.9 KEY72592.1 - 0.047 13.0 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DDE_Tnp_1_7 PF13843.6 KEY72593.1 - 2.7e-20 73.0 0.0 3.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 GATA PF00320.27 KEY72594.1 - 5e-15 54.8 5.8 9.5e-15 53.9 5.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF2587 PF10759.9 KEY72594.1 - 0.043 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-RING_9 PF13901.6 KEY72595.1 - 0.12 12.4 1.9 0.19 11.7 1.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FliL PF03748.14 KEY72595.1 - 0.33 11.5 3.3 0.59 10.7 3.1 1.6 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL THOC7 PF05615.13 KEY72595.1 - 2.2 8.5 12.6 4.6 7.5 12.6 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 TMCO5 PF14992.6 KEY72595.1 - 2.8 7.4 9.7 2.3 7.8 3.5 2.1 1 1 1 2 2 2 0 TMCO5 family PNP_UDP_1 PF01048.20 KEY72596.1 - 3.9e-05 23.0 1.6 0.00029 20.2 1.6 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ses_B PF17046.5 KEY72596.1 - 0.5 10.4 2.5 0.95 9.5 2.5 1.5 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein TPR_12 PF13424.6 KEY72597.1 - 1.1e-10 41.7 0.1 2.6e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY72597.1 - 3e-09 36.5 0.2 0.00019 21.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY72597.1 - 7.3e-05 22.5 1.7 0.011 15.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY72597.1 - 0.00019 21.3 0.2 0.19 11.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEY72597.1 - 0.0013 18.0 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KEY72597.1 - 0.0027 17.7 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.14 KEY72597.1 - 0.0098 16.4 0.6 4.3 8.2 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY72597.1 - 0.17 12.8 1.1 20 6.4 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1840 PF08895.11 KEY72598.1 - 7.1 7.0 7.8 2 8.8 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF3669 PF12417.8 KEY72601.1 - 4.5e-19 68.4 1.9 4.7e-19 68.4 0.3 1.9 2 0 0 2 2 2 1 Zinc finger protein YitT_membrane PF02588.15 KEY72603.1 - 0.01 15.2 0.9 0.01 15.2 0.9 2.2 3 0 0 3 3 3 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Acyl_transf_1 PF00698.21 KEY72604.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase domain dCMP_cyt_deam_1 PF00383.23 KEY72606.1 - 3.7e-10 39.6 2.0 6.3e-10 38.9 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY72606.1 - 1.6e-07 31.1 0.1 5.9e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 MafB19-like deaminase DDE_Tnp_1_7 PF13843.6 KEY72607.1 - 9.9e-06 25.1 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 COX2-transmemb PF09125.10 KEY72607.1 - 0.031 14.1 0.4 0.051 13.4 0.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Glyco_hydro_3 PF00933.21 KEY72609.1 - 1.1e-49 169.5 0.0 1.6e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY72609.1 - 3e-37 128.5 0.0 6.5e-37 127.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KEY72609.1 - 5.2e-18 64.9 0.2 1.1e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.18 KEY72610.1 - 5.7e-13 48.8 18.0 3.3e-08 33.5 6.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY72610.1 - 1.4e-08 34.2 0.1 2.6e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHB_acc PF05233.13 KEY72610.1 - 0.27 11.3 0.6 0.6 10.2 0.6 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain Sulfatase PF00884.23 KEY72611.1 - 1.5e-60 205.3 0.2 1.8e-60 204.9 0.2 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KEY72611.1 - 9.5e-19 67.6 4.8 1.7e-09 37.8 1.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KEY72611.1 - 7.8e-09 35.6 0.2 0.0004 20.1 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KEY72611.1 - 0.0048 15.6 0.1 0.01 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KEY72611.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sugar_tr PF00083.24 KEY72612.1 - 3.1e-102 342.7 21.3 6.2e-101 338.5 21.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72612.1 - 4.8e-18 65.2 28.6 1.5e-15 57.0 16.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.25 KEY72613.1 - 2.4e-24 86.1 0.0 3.6e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72613.1 - 9.1e-18 64.5 0.0 1.4e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEY72614.1 - 1.8e-19 70.1 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 KEY72614.1 - 2.1e-17 63.8 0.0 5.8e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 KEY72614.1 - 7.3e-14 51.7 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Blt1_C PF17183.4 KEY72614.1 - 0.079 12.6 0.2 17 5.1 0.2 2.9 2 0 0 2 2 2 0 Get5 carboxyl domain Pox_ser-thr_kin PF05445.11 KEY72614.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HD PF01966.22 KEY72617.1 - 0.00066 19.9 0.0 0.0014 18.9 0.0 1.6 1 1 0 1 1 1 1 HD domain Arylesterase PF01731.20 KEY72618.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Arylesterase GLTP PF08718.11 KEY72620.1 - 0.08 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) TauD PF02668.16 KEY72622.1 - 1.4e-16 61.1 3.0 3.1e-16 60.0 3.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEY72622.1 - 0.00065 18.9 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 CsiD ABC_tran PF00005.27 KEY72623.1 - 2.1e-44 151.3 0.0 1.4e-27 96.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY72623.1 - 6e-36 124.5 23.1 4.6e-31 108.5 9.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KEY72623.1 - 3e-08 33.4 0.3 0.0054 16.2 0.3 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KEY72623.1 - 4.7e-05 22.6 0.0 0.29 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KEY72623.1 - 0.00017 21.9 0.0 0.47 10.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEY72623.1 - 0.00044 19.9 0.2 0.32 10.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEY72623.1 - 0.00075 19.6 1.2 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY72623.1 - 0.00075 19.4 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KEY72623.1 - 0.0015 18.6 0.1 0.97 9.5 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 KEY72623.1 - 0.0021 18.6 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY72623.1 - 0.0026 18.2 0.0 5.5 7.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY72623.1 - 0.0079 16.6 0.1 2.5 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KEY72623.1 - 0.0094 15.2 0.4 3.1 7.0 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_21 PF13304.6 KEY72623.1 - 0.0096 15.8 0.2 12 5.6 0.1 3.4 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KEY72623.1 - 0.011 15.5 0.0 0.36 10.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KEY72623.1 - 0.023 14.8 0.8 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.7 KEY72623.1 - 0.035 13.0 0.0 5 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Sigma54_activat PF00158.26 KEY72623.1 - 0.073 12.8 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 KEY72623.1 - 0.074 12.3 1.7 1.6 7.9 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KEY72623.1 - 0.098 12.2 0.1 10 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KEY72623.1 - 0.26 11.3 0.7 10 6.2 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Na_H_Exchanger PF00999.21 KEY72624.1 - 3e-32 111.9 29.2 1.1e-26 93.6 21.7 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Glyco_hydro_61 PF03443.14 KEY72625.1 - 1.9e-59 201.1 0.1 2.1e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 KEY72626.1 - 8.1e-97 324.9 18.6 9.3e-97 324.7 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72626.1 - 3.5e-28 98.5 36.1 4.6e-22 78.4 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY72626.1 - 6.5e-05 21.5 0.9 6.5e-05 21.5 0.9 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEY72626.1 - 0.015 13.9 20.8 0.044 12.3 2.3 2.7 3 0 0 3 3 3 0 MFS/sugar transport protein DUF2838 PF10998.8 KEY72626.1 - 0.065 13.5 2.0 18 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2838) DUF2568 PF10823.8 KEY72626.1 - 0.098 12.9 0.4 0.098 12.9 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) DUF2530 PF10745.9 KEY72626.1 - 7.1 6.9 7.7 1.8 8.9 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Tannase PF07519.11 KEY72627.1 - 2.6e-72 244.2 0.0 3e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KEY72627.1 - 0.0003 20.1 0.0 0.00072 18.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AMP-binding PF00501.28 KEY72628.1 - 5.6e-70 236.1 0.1 1.4e-69 234.8 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KEY72628.1 - 2e-57 194.7 0.1 3.8e-57 193.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KEY72628.1 - 2.5e-55 188.0 0.0 4.2e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KEY72628.1 - 2.2e-50 171.1 0.0 2.6e-47 161.1 0.0 2.7 2 0 0 2 2 2 2 KR domain Acyl_transf_1 PF00698.21 KEY72628.1 - 7.7e-42 143.9 1.1 1.2e-41 143.2 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KEY72628.1 - 2.1e-37 129.0 0.0 4.2e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY72628.1 - 3.3e-29 101.3 0.3 1.2e-28 99.4 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KEY72628.1 - 4.4e-25 88.3 0.0 3.4e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KEY72628.1 - 2.2e-16 60.0 2.0 5.5e-10 39.5 0.2 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KEY72628.1 - 1.7e-13 51.0 0.0 4.7e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KEY72628.1 - 1.7e-13 51.1 0.0 1.1e-12 48.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEY72628.1 - 2.5e-13 49.9 0.0 4.3e-09 36.1 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 KEY72628.1 - 2.8e-12 46.6 0.0 1e-10 41.5 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KEY72628.1 - 5.1e-10 39.9 0.0 4.6e-09 36.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72628.1 - 5.6e-09 36.0 0.0 2.3e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72628.1 - 3.1e-07 30.9 0.0 1.2e-06 29.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY72628.1 - 9e-07 28.9 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KEY72628.1 - 7.3e-05 21.9 0.0 0.0003 19.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KEY72628.1 - 0.0012 18.5 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KEY72628.1 - 0.0038 18.2 0.0 0.035 15.1 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 KEY72628.1 - 0.017 14.5 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 KEY72628.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Semialdhyde_dh PF01118.24 KEY72628.1 - 0.089 13.2 0.2 1.2 9.5 0.0 2.8 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 KEY72629.1 - 0.06 13.5 13.2 0.11 12.7 13.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEY72631.1 - 2.6e-38 131.9 0.0 3.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Type_III_YscX PF09474.10 KEY72631.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) MFS_1 PF07690.16 KEY72632.1 - 1.8e-39 135.7 48.7 1.3e-38 132.9 48.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72632.1 - 4.3e-11 42.3 14.6 4.3e-11 42.3 14.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY72632.1 - 9.8e-08 30.9 14.6 1.5e-07 30.3 14.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.26 KEY72633.1 - 6.5e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY72633.1 - 0.00022 21.1 0.1 0.0014 18.5 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEY72633.1 - 0.071 13.0 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase HlyIII PF03006.20 KEY72634.1 - 8.2e-26 91.1 8.7 9.3e-26 90.9 8.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related LrgA PF03788.14 KEY72635.1 - 0.056 13.4 0.2 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 LrgA family p450 PF00067.22 KEY72636.1 - 7.1e-40 137.1 0.0 8.7e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KEY72637.1 - 7.3e-84 282.2 24.3 9.1e-84 281.9 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72637.1 - 3.4e-12 45.9 54.7 1.8e-11 43.6 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEY72638.1 - 1.4e-34 119.6 27.8 1.4e-34 119.6 27.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72638.1 - 5.5e-06 25.5 30.3 1.8e-05 23.8 30.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2244 PF10003.9 KEY72638.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.3 3 1 0 3 3 3 0 Integral membrane protein (DUF2244) FPN1 PF06963.12 KEY72639.1 - 4.6e-105 351.7 20.3 5.7e-105 351.4 20.3 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF2651 PF10852.8 KEY72639.1 - 3.6 8.3 8.9 22 5.8 0.7 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) HET PF06985.11 KEY72640.1 - 3.4e-28 98.8 0.0 5.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KEY72641.1 - 5.4e-15 55.1 0.0 7e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ldh_2 PF02615.14 KEY72641.1 - 0.15 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase ketoacyl-synt PF00109.26 KEY72642.1 - 8.2e-62 209.1 0.0 1.6e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY72642.1 - 6.5e-36 122.9 0.2 4.8e-35 120.1 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEY72642.1 - 1.5e-17 64.1 0.1 2.4e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY72642.1 - 1.1e-16 61.3 0.4 2e-16 60.4 0.4 1.5 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KEY72642.1 - 3.4e-11 43.6 0.0 6.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KEY72642.1 - 1.1e-10 42.7 0.0 8e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY72642.1 - 0.0003 20.3 0.1 0.00053 19.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KEY72642.1 - 0.00057 19.9 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 KEY72642.1 - 0.002 17.6 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KEY72642.1 - 0.0056 17.3 0.3 0.024 15.2 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Polysacc_synt_2 PF02719.15 KEY72642.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KEY72642.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CttA_N PF18244.1 KEY72643.1 - 0.044 14.2 0.2 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain DDE_Tnp_4 PF13359.6 KEY72644.1 - 2.4e-21 76.1 0.0 4.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEY72644.1 - 6.1e-10 39.1 0.0 1.7e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain RE_NgoPII PF09521.10 KEY72644.1 - 0.0092 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 NgoPII restriction endonuclease YPEB PF14620.6 KEY72644.1 - 0.01 15.2 1.3 1.8 7.8 0.3 2.1 2 0 0 2 2 2 2 YpeB sporulation DUF4018 PF13210.6 KEY72644.1 - 0.039 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Chal_sti_synt_N PF00195.19 KEY72645.1 - 2.7e-19 69.5 0.1 4.3e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KEY72645.1 - 4.6e-06 26.1 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Nop52 PF05997.12 KEY72645.1 - 0.099 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 COX14 PF14880.6 KEY72645.1 - 8.1 6.4 7.9 1.7 8.5 2.2 2.6 2 1 0 2 2 2 0 Cytochrome oxidase c assembly DUF3435 PF11917.8 KEY72646.1 - 0.0016 17.4 1.8 0.0034 16.4 1.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.24 KEY72647.1 - 0.046 13.6 0.2 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain bZIP_1 PF00170.21 KEY72649.1 - 1.7e-08 34.4 6.7 1.7e-08 34.4 6.7 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEY72649.1 - 1.9e-05 24.7 7.2 1.9e-05 24.7 7.2 2.1 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY72649.1 - 0.0063 17.0 11.6 0.016 15.7 11.6 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor HisKA PF00512.25 KEY72650.1 - 2.1e-08 34.1 0.0 5.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KEY72650.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 PAS domain DUF2884 PF11101.8 KEY72651.1 - 0.004 16.7 0.7 0.0066 16.0 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) CortBP2 PF09727.9 KEY72651.1 - 0.0081 16.1 2.5 0.013 15.4 2.5 1.4 1 0 0 1 1 1 1 Cortactin-binding protein-2 GBP_C PF02841.14 KEY72651.1 - 0.018 14.5 3.7 0.023 14.1 3.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Apolipoprotein PF01442.18 KEY72651.1 - 0.037 13.9 3.7 0.048 13.5 3.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.6 KEY72651.1 - 0.068 13.6 3.2 0.59 10.6 0.1 2.5 1 1 0 2 2 2 0 Snapin/Pallidin MRF_C1 PF13887.6 KEY72651.1 - 0.092 11.9 0.0 0.22 10.7 0.0 1.7 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 CdvA PF18822.1 KEY72651.1 - 0.18 11.6 4.3 0.45 10.3 1.5 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain HSP70 PF00012.20 KEY72652.1 - 5.4e-26 90.9 0.0 5.4e-26 90.9 0.0 3.0 3 0 0 3 3 3 2 Hsp70 protein CDC45 PF02724.14 KEY72652.1 - 0.058 11.7 8.4 0.07 11.4 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C25_C PF03785.14 KEY72652.1 - 0.086 12.7 0.0 2.4 8.1 0.0 2.6 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain DUF3391 PF11871.8 KEY72652.1 - 7.6 7.1 8.2 16 6.0 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2884 PF11101.8 KEY72654.1 - 0.00052 19.6 1.1 0.00065 19.3 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) CortBP2 PF09727.9 KEY72654.1 - 0.0074 16.2 2.0 0.0091 15.9 2.0 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 Apolipoprotein PF01442.18 KEY72654.1 - 0.012 15.5 2.2 0.013 15.3 2.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain GBP_C PF02841.14 KEY72654.1 - 0.013 14.9 3.5 0.015 14.7 3.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Snapin_Pallidin PF14712.6 KEY72654.1 - 0.016 15.6 3.7 0.37 11.3 0.1 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF4795 PF16043.5 KEY72654.1 - 0.022 14.4 1.5 0.025 14.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 KEY72654.1 - 0.031 14.3 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Arnt_C PF18583.1 KEY72654.1 - 0.034 13.7 0.1 0.27 10.9 0.0 2.0 1 1 1 2 2 2 0 Aminoarabinose transferase C-terminal domain CdvA PF18822.1 KEY72654.1 - 0.044 13.6 4.7 0.13 12.1 1.6 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FliD_C PF07195.12 KEY72654.1 - 0.046 13.1 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus SnAPC_2_like PF11035.8 KEY72654.1 - 0.049 13.8 2.1 0.054 13.6 2.1 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Phage_Mu_Gam PF07352.12 KEY72654.1 - 0.051 13.5 2.3 0.068 13.1 2.3 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1664 PF07889.12 KEY72654.1 - 0.17 11.9 2.5 0.25 11.4 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NolV PF06635.12 KEY72654.1 - 0.2 11.0 3.3 0.6 9.4 0.4 2.0 1 1 1 2 2 2 0 Nodulation protein NolV PcfK PF14058.6 KEY72655.1 - 0.032 14.5 3.5 0.044 14.1 3.5 1.3 1 0 0 1 1 1 0 PcfK-like protein Coilin_N PF15862.5 KEY72655.1 - 0.3 10.9 6.2 0.44 10.3 6.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus HSP70 PF00012.20 KEY72656.1 - 1.7e-24 86.0 0.0 2.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.11 KEY72656.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 StbA protein p450 PF00067.22 KEY72657.1 - 1.5e-11 43.7 0.0 1.2e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4064 PF13273.6 KEY72658.1 - 2.8 8.2 5.1 13 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) p450 PF00067.22 KEY72659.1 - 2.3e-51 175.0 0.0 3.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dimerisation PF08100.11 KEY72659.1 - 0.11 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain adh_short PF00106.25 KEY72660.1 - 4.5e-25 88.2 1.6 1.1e-14 54.4 0.8 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72660.1 - 2.3e-21 76.5 0.9 2e-11 43.9 0.0 2.9 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72660.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KEY72660.1 - 0.017 15.1 0.1 1.2 9.1 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KEY72660.1 - 0.07 12.9 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain IFRD PF05004.13 KEY72660.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HTH_Tnp_Tc3_2 PF01498.18 KEY72661.1 - 3.7e-11 43.1 0.8 4.5e-11 42.8 0.8 1.1 1 0 0 1 1 1 1 Transposase Sigma_1s PF02454.16 KEY72661.1 - 0.025 14.6 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Sigma 1s protein HTH_23 PF13384.6 KEY72661.1 - 0.034 13.9 0.6 0.034 13.9 0.6 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_M14 PF00246.24 KEY72662.1 - 5.6e-41 141.2 0.4 7.2e-41 140.9 0.4 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase GATase PF00117.28 KEY72663.1 - 4.9e-06 26.4 0.0 8.9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I p450 PF00067.22 KEY72664.1 - 3.8e-68 230.3 0.0 4.4e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 KEY72667.1 - 9.2e-85 284.6 35.4 5.1e-44 151.0 17.1 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY72667.1 - 2.3e-68 229.0 0.0 5.7e-34 117.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEY72667.1 - 2e-15 56.8 0.5 2.3e-05 23.9 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KEY72667.1 - 8.3e-09 34.7 1.6 0.035 12.9 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KEY72667.1 - 9.9e-08 31.6 1.0 0.001 18.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY72667.1 - 1.6e-07 31.7 0.2 0.012 15.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY72667.1 - 3.7e-07 30.2 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEY72667.1 - 1.4e-06 28.8 1.0 0.055 13.9 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEY72667.1 - 2.8e-05 24.1 1.5 0.14 11.9 0.1 4.6 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEY72667.1 - 3.4e-05 23.7 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KEY72667.1 - 6.7e-05 23.5 0.1 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEY72667.1 - 7.7e-05 22.5 2.1 0.35 10.6 0.1 4.3 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 KEY72667.1 - 0.00011 22.7 0.9 2.3 8.6 0.0 4.9 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEY72667.1 - 0.00015 21.4 2.5 0.28 10.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEY72667.1 - 0.00042 20.9 0.0 1.6 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KEY72667.1 - 0.0014 18.7 0.0 2.3 8.3 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KEY72667.1 - 0.0015 18.8 0.0 0.89 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY72667.1 - 0.0024 18.0 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KEY72667.1 - 0.0034 17.3 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 KEY72667.1 - 0.004 17.3 0.1 3.6 7.6 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KEY72667.1 - 0.0055 16.9 1.7 6.5 7.1 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KEY72667.1 - 0.018 15.0 0.0 11 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEY72667.1 - 0.024 15.0 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 KEY72667.1 - 0.031 13.4 0.0 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 KEY72667.1 - 0.037 13.5 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEY72667.1 - 0.038 13.3 0.1 7.4 5.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 KEY72667.1 - 0.084 12.6 0.2 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 KEY72667.1 - 0.098 12.4 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KEY72667.1 - 0.12 11.6 0.4 7 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2852 PF11014.8 KEY72667.1 - 0.19 11.9 0.3 9.8 6.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) AAA_24 PF13479.6 KEY72667.1 - 0.2 11.3 0.4 8.4 6.1 0.2 2.7 2 0 0 2 2 2 0 AAA domain GP41 PF00517.17 KEY72667.1 - 0.41 10.5 2.1 0.66 9.8 1.1 1.9 1 1 0 1 1 1 0 Retroviral envelope protein Fungal_trans PF04082.18 KEY72668.1 - 1.7e-05 24.0 0.0 0.00013 21.1 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Melibiase_2 PF16499.5 KEY72669.1 - 6e-55 186.4 4.4 1.9e-41 142.1 0.3 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KEY72669.1 - 2.8e-11 43.3 0.2 1.9e-09 37.5 0.0 3.0 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KEY72669.1 - 3.8e-05 22.8 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Melibiase DUF4387 PF14330.6 KEY72670.1 - 7.5e-33 113.1 0.0 1.5e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KEY72670.1 - 1.5e-11 43.6 0.0 2.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA PAD PF03068.15 KEY72671.1 - 1.1e-104 350.5 0.0 1.7e-104 350.0 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Big_1 PF02369.16 KEY72671.1 - 0.42 10.7 3.8 3.2 7.8 0.3 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Glyco_hydro_61 PF03443.14 KEY72672.1 - 5e-61 206.2 0.0 5.7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RbcS PF12338.8 KEY72672.1 - 0.077 13.2 2.1 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit 6PGD PF00393.19 KEY72673.1 - 3.1e-87 292.6 0.0 3.9e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEY72673.1 - 3.9e-29 101.9 0.1 3.1e-27 95.7 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KEY72673.1 - 1.9e-07 31.1 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEY72673.1 - 4e-07 30.4 0.0 8.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KEY72673.1 - 0.00013 22.0 0.0 0.00038 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KEY72673.1 - 0.00047 19.6 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEY72673.1 - 0.00055 20.5 0.0 0.0042 17.6 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KEY72673.1 - 0.0017 17.9 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KEY72673.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 KEY72673.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_11 PF14833.6 KEY72673.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Con-6 PF10346.9 KEY72674.1 - 5.9e-17 61.4 1.3 9.2e-17 60.8 1.3 1.3 1 0 0 1 1 1 1 Conidiation protein 6 PHD PF00628.29 KEY72676.1 - 0.01 15.7 1.3 0.026 14.4 1.3 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KEY72676.1 - 0.028 14.6 2.0 0.084 13.1 2.0 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KEY72676.1 - 1.7 9.0 5.0 0.34 11.2 1.3 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain Zn_clus PF00172.18 KEY72677.1 - 0.0002 21.4 2.2 0.00036 20.6 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.18 KEY72681.1 - 9.3e-13 47.9 6.9 3.3e-12 46.1 6.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KEY72681.1 - 1.7e-06 28.6 0.2 2.4e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zn_clus PF00172.18 KEY72682.1 - 9.1e-05 22.5 12.5 0.00014 21.9 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 KEY72682.1 - 0.41 10.2 12.3 0.78 9.3 12.3 1.4 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 KEY72682.1 - 0.8 8.7 7.3 0.15 11.1 3.3 1.8 2 0 0 2 2 2 0 Drosophila roughex protein Zip PF02535.22 KEY72682.1 - 2.5 7.2 5.7 4.2 6.5 5.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KEY72682.1 - 3.3 6.4 4.0 5.7 5.6 4.0 1.3 1 0 0 1 1 1 0 Presenilin NAD_binding_1 PF00175.21 KEY72684.1 - 5e-12 46.4 0.0 1.5e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KEY72684.1 - 1.8e-09 38.1 0.0 3.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KEY72684.1 - 1.4e-06 28.6 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KEY72684.1 - 0.00011 22.2 0.1 0.00024 21.0 0.1 1.6 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KEY72684.1 - 0.0033 17.6 0.3 0.024 14.8 0.1 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain zf-C2HC PF01530.18 KEY72685.1 - 0.11 12.7 0.2 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2HC type Glycos_transf_1 PF00534.20 KEY72686.1 - 6.4e-25 87.7 0.0 1.2e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY72686.1 - 1e-16 61.6 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEY72686.1 - 7.3e-07 29.5 0.0 2.3e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Sod_Fe_C PF02777.18 KEY72687.1 - 6.6e-37 125.8 0.0 1.1e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEY72687.1 - 9.7e-32 109.3 0.6 1.6e-31 108.6 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 KEY72688.1 - 7.6e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein TauD PF02668.16 KEY72689.1 - 7e-49 167.0 1.1 7.9e-49 166.8 1.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CaM-KIIN PF15170.6 KEY72691.1 - 0.0099 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 1 Calcium/calmodulin-dependent protein kinase II inhibitor PRKCSH PF07915.13 KEY72692.1 - 2.7e-16 60.4 0.0 8.9e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4177 PF13783.6 KEY72692.1 - 0.031 14.6 0.3 3.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) HrpJ PF07201.11 KEY72692.1 - 0.09 13.1 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 HrpJ-like domain Cnn_1N PF07989.11 KEY72693.1 - 3.5e-07 30.3 1.8 1.2e-06 28.6 1.8 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Spc42p PF11544.8 KEY72693.1 - 0.13 12.3 1.0 0.34 10.9 1.0 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p DivIVA PF05103.13 KEY72693.1 - 0.49 10.5 4.6 0.58 10.2 3.3 1.8 2 0 0 2 2 2 0 DivIVA protein DPBB_1 PF03330.18 KEY72694.1 - 5.8e-09 36.1 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KEY72694.1 - 0.00013 21.8 0.2 0.0002 21.2 0.2 1.2 1 0 0 1 1 1 1 Barwin family HET PF06985.11 KEY72696.1 - 4.6e-36 124.4 0.1 9.4e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mur_ligase_M PF08245.12 KEY72697.1 - 5e-08 33.2 0.0 4.5e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEY72697.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Abhydrolase_6 PF12697.7 KEY72698.1 - 3.8e-09 37.5 0.9 6.1e-09 36.8 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72698.1 - 3e-08 33.2 0.0 4.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEY72698.1 - 7.2e-05 22.7 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KEY72698.1 - 0.0073 16.0 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold TFIIA PF03153.13 KEY72699.1 - 1.9 8.4 12.8 3.1 7.7 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dynamin_N PF00350.23 KEY72700.1 - 4e-39 134.3 0.3 1.1e-38 132.9 0.1 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEY72700.1 - 1.5e-27 96.6 0.0 2.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KEY72700.1 - 9.1e-06 25.7 0.2 8.7e-05 22.6 0.0 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KEY72700.1 - 0.071 12.8 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Ribonuclease PF00545.20 KEY72701.1 - 2.3e-07 31.5 0.0 3.6e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 ribonuclease MFS_1 PF07690.16 KEY72702.1 - 4e-33 114.8 34.3 1e-32 113.4 34.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease PF00324.21 KEY72704.1 - 5.7e-100 335.2 42.0 6.5e-100 335.0 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY72704.1 - 9.2e-27 93.9 44.0 1.1e-26 93.7 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease Esterase_phd PF10503.9 KEY72707.1 - 5.3e-21 75.1 0.6 8.1e-21 74.5 0.6 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEY72707.1 - 6.3e-09 35.6 0.4 9.9e-09 35.0 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KEY72707.1 - 4.8e-05 23.1 0.2 7.5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KEY72707.1 - 0.0013 18.6 0.2 0.0026 17.6 0.2 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KEY72707.1 - 0.0033 17.0 1.1 0.0062 16.2 1.1 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KEY72707.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KEY72707.1 - 0.088 11.5 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KEY72707.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Utp12 PF04003.12 KEY72708.1 - 5.3e-23 81.4 0.1 7.7e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.25 KEY72709.1 - 3.6e-29 100.7 0.0 1.6e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KEY72709.1 - 2.2e-14 53.3 2.7 5.8e-14 52.0 2.7 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Corona_RPol_N PF06478.13 KEY72709.1 - 0.045 12.8 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus NUDIX PF00293.28 KEY72710.1 - 4.5e-06 26.7 0.0 7.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KEY72710.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) HSP70 PF00012.20 KEY72711.1 - 1.2e-07 30.4 0.1 5.3e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein SET PF00856.28 KEY72711.1 - 1.1e-05 25.9 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SET domain Trypan_PARP PF05887.11 KEY72711.1 - 0.00031 20.7 6.3 0.00087 19.3 6.3 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FtsA PF14450.6 KEY72711.1 - 0.015 15.7 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA SPESP1 PF15754.5 KEY72711.1 - 4.2 6.4 4.6 8.4 5.5 4.6 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Pkinase PF00069.25 KEY72712.1 - 1.1e-56 192.1 0.0 1.7e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72712.1 - 1.3e-32 113.1 0.0 6.6e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY72712.1 - 0.0077 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEY72712.1 - 0.019 14.3 0.3 0.04 13.3 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KEY72712.1 - 0.026 13.5 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 KEY72713.1 - 1.5e-16 60.7 6.8 2.7e-16 59.9 6.8 1.4 1 0 0 1 1 1 1 Stc1 domain zf-RING_7 PF02591.15 KEY72713.1 - 0.075 13.2 0.2 0.2 11.9 0.2 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain BCDHK_Adom3 PF10436.9 KEY72714.1 - 1.3e-76 255.9 0.0 1.9e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEY72714.1 - 7.5e-13 49.0 0.0 1.8e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEY72714.1 - 0.043 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Exonuc_VII_L PF02601.15 KEY72715.1 - 0.031 13.9 5.2 0.041 13.5 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3915 PF13054.6 KEY72715.1 - 0.17 11.9 1.2 0.28 11.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) NBP1 PF08537.10 KEY72715.1 - 0.46 9.8 12.0 1.5 8.2 12.2 1.5 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 HMMR_N PF15905.5 KEY72715.1 - 9.9 5.5 19.4 20 4.5 19.4 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Pyridoxal_deC PF00282.19 KEY72717.1 - 8.2e-19 67.5 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KEY72717.1 - 1.5e-06 27.5 0.0 2.6e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEY72717.1 - 4.7e-05 22.9 0.0 7.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 KEY72718.1 - 5.4e-69 232.5 0.0 6.8e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RINGv PF12906.7 KEY72719.1 - 7.4e-09 35.6 5.3 9.4e-09 35.3 1.3 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KEY72719.1 - 0.016 15.5 4.3 0.14 12.5 1.5 2.3 2 0 0 2 2 2 0 Ring finger domain PHD_4 PF16866.5 KEY72719.1 - 0.05 13.7 1.9 0.52 10.4 1.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-MIZ PF02891.20 KEY72719.1 - 0.083 12.7 1.9 0.17 11.6 1.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD PF00628.29 KEY72719.1 - 2.3 8.2 6.7 0.4 10.6 2.7 1.7 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 KEY72720.1 - 3e-56 189.9 0.1 1.7e-33 115.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KEY72720.1 - 1.2e-10 40.9 0.3 3.1e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KEY72720.1 - 0.21 10.3 0.5 4.8 5.8 0.1 2.2 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RCC1_2 PF13540.6 KEY72721.1 - 1.4e-07 31.1 6.2 0.0007 19.3 0.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KEY72721.1 - 7.3e-07 29.7 0.6 0.3 11.7 0.2 5.3 4 1 1 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Ribonuclease_3 PF00636.26 KEY72722.1 - 8.2e-42 142.1 0.0 3.8e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEY72722.1 - 5.2e-23 81.6 0.0 1.3e-09 38.3 0.0 3.6 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KEY72722.1 - 6.1e-23 80.8 0.1 2.1e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 KEY72722.1 - 5e-20 72.0 0.0 1.1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY72722.1 - 6.6e-20 71.5 0.0 1.6e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY72722.1 - 4.4e-13 49.6 0.0 7.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KEY72722.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DEAD_2 PF06733.15 KEY72722.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_18 PF13238.6 KEY72723.1 - 1.3e-05 25.7 0.0 2.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KEY72723.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 KEY72723.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KEY72723.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY72723.1 - 0.061 13.7 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KEY72723.1 - 0.084 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEY72723.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY72723.1 - 0.2 12.2 0.0 0.43 11.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PTH2 PF01981.16 KEY72724.1 - 1e-47 161.2 0.1 1.5e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.11 KEY72725.1 - 1.7e-38 130.3 0.2 1.2e-34 117.9 0.0 3.5 4 0 0 4 4 4 2 BING4CT (NUC141) domain WD40 PF00400.32 KEY72725.1 - 2.6e-05 24.9 0.0 0.12 13.3 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KEY72725.1 - 7.7e-05 21.9 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region NIL PF09383.10 KEY72725.1 - 0.0077 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 NIL domain RIBIOP_C PF04950.12 KEY72726.1 - 5.2e-110 367.4 0.0 8.6e-110 366.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KEY72726.1 - 2.6e-17 62.7 0.0 5.8e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 KEY72727.1 - 7.9e-34 116.8 0.0 1.4e-33 115.9 0.0 1.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KEY72727.1 - 2.5e-06 26.7 0.1 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KEY72727.1 - 0.0093 16.5 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEY72727.1 - 0.01 15.9 0.0 0.039 14.0 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEY72727.1 - 0.12 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain KOW PF00467.29 KEY72728.1 - 0.17 11.9 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 KOW motif PIN_8 PF18476.1 KEY72728.1 - 2.4 8.0 7.7 0.76 9.6 0.2 2.2 2 0 0 2 2 2 0 PIN like domain GCN5L1 PF06320.13 KEY72728.1 - 4.6 7.4 12.2 2.9 8.1 0.8 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF5633 PF18656.1 KEY72728.1 - 5.5 7.0 7.3 2.4 8.1 3.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5633) Hep_59 PF07052.11 KEY72728.1 - 6.2 7.6 10.8 0.88 10.4 1.3 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Ras PF00071.22 KEY72729.1 - 2.5e-51 173.5 0.0 6.6e-51 172.1 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEY72729.1 - 2.9e-21 75.9 0.0 4.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY72729.1 - 7.3e-06 25.5 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEY72729.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KEY72729.1 - 0.062 12.5 0.1 0.63 9.2 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Aa_trans PF01490.18 KEY72730.1 - 9.4e-72 241.9 30.4 1.2e-71 241.6 30.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.6 KEY72730.1 - 0.034 13.9 12.4 0.049 13.4 4.6 2.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Asp PF00026.23 KEY72731.1 - 1.2e-64 218.8 0.2 1.5e-64 218.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY72731.1 - 3.7e-12 46.9 5.0 4.9e-10 39.9 0.9 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY72731.1 - 0.0013 19.4 0.0 0.47 11.1 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KEY72731.1 - 0.0077 16.8 0.0 0.047 14.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease PPTA PF01239.22 KEY72733.1 - 2.9e-05 23.6 11.3 0.0067 16.1 0.7 4.4 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat DUF627 PF04781.12 KEY72733.1 - 0.074 13.1 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF627) CHD5 PF04420.14 KEY72734.1 - 4.7e-63 211.8 0.7 6.1e-63 211.4 0.7 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF1515 PF07439.11 KEY72734.1 - 0.099 12.7 0.6 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PcfJ PF14284.6 KEY72734.1 - 0.12 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 PcfJ-like protein MADF_DNA_bdg PF10545.9 KEY72734.1 - 0.37 11.2 2.9 2.6 8.4 2.9 2.1 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1772 PF08592.11 KEY72735.1 - 0.025 14.9 7.8 0.27 11.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) TrbC PF04956.13 KEY72735.1 - 0.12 12.5 6.2 1.4 9.2 0.4 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family GRAB PF10375.9 KEY72736.1 - 4.9e-09 35.7 0.1 9.6e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KEY72736.1 - 0.0018 17.2 28.6 0.0018 17.2 28.6 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein Filament PF00038.21 KEY72736.1 - 0.018 14.6 48.9 0.25 10.9 12.8 2.7 1 1 1 2 2 2 0 Intermediate filament protein RPW8 PF05659.11 KEY72736.1 - 0.037 13.7 0.7 0.037 13.7 0.7 3.9 1 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Golgin_A5 PF09787.9 KEY72736.1 - 0.13 11.7 51.7 0.017 14.6 22.9 3.5 1 1 3 4 4 4 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KEY72736.1 - 0.71 9.9 64.1 0.076 13.1 11.6 4.9 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KEY72736.1 - 0.79 9.4 46.5 0.56 9.9 2.8 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 KEY72736.1 - 1.4 9.4 17.4 0.4 11.2 1.3 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HicB_lk_antitox PF15919.5 KEY72736.1 - 1.8 8.7 6.5 0.48 10.5 0.3 2.6 2 1 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Fib_alpha PF08702.10 KEY72736.1 - 1.9 8.6 29.0 3 8.0 3.0 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KEY72736.1 - 3 6.9 46.0 0.015 14.4 18.3 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KEY72736.1 - 3.8 7.6 27.2 4.2 7.4 2.8 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) ERM PF00769.19 KEY72736.1 - 3.8 7.2 67.0 0.55 10.0 21.1 3.3 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.12 KEY72736.1 - 4.1 7.5 21.8 0.59 10.2 2.3 3.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KEY72736.1 - 5.5 7.0 56.7 0.15 12.1 17.3 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2935 PF11155.8 KEY72736.1 - 6.1 7.2 8.4 15 5.9 0.6 3.6 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) MAD PF05557.13 KEY72736.1 - 7.8 4.7 51.4 0.074 11.4 34.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF3138 PF11336.8 KEY72736.1 - 9.5 4.7 16.8 0.096 11.3 2.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) RRM_1 PF00076.22 KEY72737.1 - 1.8e-16 59.7 0.0 3.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY72737.1 - 0.0004 20.0 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEY72737.1 - 0.024 14.6 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KEY72737.1 - 0.064 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 SMN PF06003.12 KEY72738.1 - 9.7e-11 41.4 5.5 6.8e-09 35.4 0.5 2.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Cu_bind_like PF02298.17 KEY72739.1 - 0.019 15.0 0.1 0.099 12.7 0.1 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain DUF872 PF05915.12 KEY72740.1 - 0.63 10.2 2.9 0.87 9.8 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) VHS PF00790.19 KEY72741.1 - 2.8e-06 27.2 0.0 1.2e-05 25.2 0.0 2.0 2 1 1 3 3 3 1 VHS domain CTD_bind PF04818.13 KEY72741.1 - 1.9e-05 25.4 0.0 5.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KEY72741.1 - 0.0016 18.9 2.3 0.007 16.8 2.3 2.0 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 KEY72741.1 - 0.056 14.3 2.1 4.5 8.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KEY72741.1 - 2 8.4 5.4 3.6 7.6 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MgsA_C PF12002.8 KEY72742.1 - 2.8e-61 206.3 0.1 6.1e-61 205.2 0.0 1.6 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KEY72742.1 - 4.9e-24 84.5 0.3 1e-23 83.4 0.3 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KEY72742.1 - 2.4e-13 50.6 0.0 4.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEY72742.1 - 2.1e-08 34.1 0.0 5.8e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY72742.1 - 2e-06 28.3 1.6 0.0027 18.1 0.0 3.3 1 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 KEY72742.1 - 1.6e-05 24.7 0.0 0.00074 19.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 KEY72742.1 - 6.7e-05 23.2 0.1 0.00026 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEY72742.1 - 8.1e-05 22.1 0.1 0.19 11.1 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEY72742.1 - 0.00011 22.2 0.2 0.0028 17.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KEY72742.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEY72742.1 - 0.00075 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 KEY72742.1 - 0.0019 18.2 0.1 1.2 9.1 0.0 2.2 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KEY72742.1 - 0.004 17.0 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TRAF6_Z2 PF18048.1 KEY72742.1 - 0.009 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor 6 zinc finger 2 TIP49 PF06068.13 KEY72742.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 KEY72742.1 - 0.027 14.2 0.0 2.8 7.7 0.0 2.5 2 1 1 3 3 3 0 DNA polymerase III, delta subunit AAA_24 PF13479.6 KEY72742.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KEY72742.1 - 0.07 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein SKI PF01202.22 KEY72742.1 - 0.075 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_23 PF13476.6 KEY72742.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY72742.1 - 0.12 12.6 0.7 0.44 10.8 0.7 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY72742.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 KEY72742.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KEY72742.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIN_9 PF18477.1 KEY72742.1 - 0.16 12.3 0.1 1.1 9.5 0.0 2.4 2 1 1 3 3 3 0 PIN like domain NB-ARC PF00931.22 KEY72742.1 - 0.23 10.6 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SOG2 PF10428.9 KEY72742.1 - 3.7 6.6 6.1 5.4 6.1 6.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein XPG_I PF00867.18 KEY72743.1 - 6.4e-27 93.8 0.0 1.4e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KEY72743.1 - 3.3e-25 89.0 0.3 8.9e-25 87.6 0.3 1.8 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KEY72743.1 - 0.00071 20.0 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain tRNA-synt_2b PF00587.25 KEY72744.1 - 1.9e-18 67.1 0.0 3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.19 KEY72744.1 - 1.2e-17 63.7 0.0 4.7e-17 61.7 0.0 2.0 2 1 0 2 2 2 1 Actin Seryl_tRNA_N PF02403.22 KEY72744.1 - 9.7e-10 38.6 2.5 1.8e-09 37.7 2.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 KEY72746.1 - 4.8e-75 252.3 0.0 6.6e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72746.1 - 1.6e-30 106.3 0.0 7.8e-22 77.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY72746.1 - 2.1e-06 27.3 0.0 0.45 9.8 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KEY72746.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEY72746.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY72746.1 - 0.12 12.3 0.0 2.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FOXP-CC PF16159.5 KEY72748.1 - 0.002 18.7 1.4 0.14 12.8 0.2 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain AT_hook PF02178.19 KEY72748.1 - 0.2 11.6 15.4 0.14 12.1 4.5 2.8 2 0 0 2 2 2 0 AT hook motif zf-C2H2_aberr PF17017.5 KEY72748.1 - 0.25 11.5 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger GFA PF04828.14 KEY72749.1 - 4.5e-06 26.9 0.4 4.5e-06 26.9 0.4 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2661 PF10860.8 KEY72749.1 - 0.0012 18.9 0.1 0.0017 18.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2661) A2L_zn_ribbon PF08792.10 KEY72749.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Yippee-Mis18 PF03226.14 KEY72749.1 - 0.12 12.6 2.0 0.51 10.6 2.3 1.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HscB_4_cys PF18256.1 KEY72749.1 - 0.17 11.8 0.3 0.17 11.8 0.3 2.2 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif C2 PF00168.30 KEY72750.1 - 2.1e-28 98.6 0.0 5.2e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain adh_short_C2 PF13561.6 KEY72751.1 - 9.4e-33 113.7 2.0 2.2e-30 106.0 2.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY72751.1 - 5.6e-30 104.3 3.6 1.3e-18 67.2 0.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY72751.1 - 3.6e-11 43.3 2.3 3.7e-10 40.0 2.3 2.2 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KEY72751.1 - 0.0032 17.5 0.1 0.005 16.9 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEY72751.1 - 0.014 15.3 0.5 0.079 12.8 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H-binding F420_oxidored PF03807.17 KEY72751.1 - 0.087 13.4 0.9 0.26 11.9 0.9 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KEY72753.1 - 1.7e-40 139.1 40.1 1.7e-40 139.1 40.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72753.1 - 1.8e-08 33.7 11.6 1.8e-08 33.7 11.6 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 KEY72754.1 - 7.2e-109 364.6 25.9 8.8e-109 364.4 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72754.1 - 2.2e-20 72.9 34.3 2.2e-20 72.9 34.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY72754.1 - 0.002 17.1 0.3 0.002 17.1 0.3 2.9 2 1 1 3 3 3 1 MFS_1 like family Peptidase_C12 PF01088.21 KEY72755.1 - 4.4e-50 170.4 0.0 5.1e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AIP3 PF03915.13 KEY72756.1 - 1.5e-157 524.9 7.4 2.8e-157 524.0 7.4 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1664 PF07889.12 KEY72756.1 - 0.0012 18.9 5.0 0.032 14.3 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) MIP-T3_C PF17749.1 KEY72756.1 - 0.013 15.5 3.3 0.052 13.5 0.4 3.0 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region GNVR PF13807.6 KEY72756.1 - 0.04 13.8 0.3 0.96 9.4 0.1 2.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Lectin_N PF03954.14 KEY72756.1 - 0.048 13.4 0.1 0.048 13.4 0.1 3.2 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FliL PF03748.14 KEY72756.1 - 0.062 13.9 0.1 0.42 11.2 0.1 2.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL CHDCT2 PF08074.11 KEY72756.1 - 0.077 13.2 2.7 9.5 6.4 0.1 3.0 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.12 KEY72756.1 - 2.4 8.7 9.0 0.94 10.0 0.1 3.8 4 1 0 4 4 2 0 Nucleopolyhedrovirus P10 protein FH2 PF02181.23 KEY72756.1 - 3.7 6.6 6.7 0.25 10.4 0.3 2.3 3 0 0 3 3 3 0 Formin Homology 2 Domain CK2S PF15011.6 KEY72756.1 - 3.9 7.3 6.9 26 4.6 0.1 4.0 4 0 0 4 4 4 0 Casein Kinase 2 substrate Med11 PF10280.9 KEY72756.1 - 5.1 7.5 7.1 2.3 8.7 1.4 3.4 3 1 0 3 3 3 0 Mediator complex protein IKI3 PF04762.12 KEY72757.1 - 8.6e-300 997.0 0.0 3.3e-298 991.8 0.0 2.0 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KEY72757.1 - 0.00029 21.1 0.9 17 5.8 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KEY72757.1 - 1.3 10.0 12.9 22 6.2 0.5 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Phasin_2 PF09361.10 KEY72757.1 - 2 8.7 3.7 31 4.9 0.4 3.0 3 0 0 3 3 3 0 Phasin protein DUF3984 PF13136.6 KEY72758.1 - 2e-61 208.2 23.2 3.2e-60 204.3 23.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) RAP1 PF07218.11 KEY72758.1 - 1.7 6.8 3.2 2.4 6.4 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hpt PF01627.23 KEY72759.1 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Hpt domain Ribonuc_L-PSP PF01042.21 KEY72759.1 - 0.017 15.2 0.0 0.39 10.7 0.0 2.1 1 1 1 2 2 2 0 Endoribonuclease L-PSP Tup_N PF08581.10 KEY72759.1 - 0.079 13.3 0.7 0.18 12.1 0.5 1.7 2 0 0 2 2 2 0 Tup N-terminal AKAP7_NLS PF10469.9 KEY72760.1 - 2.6e-28 99.3 0.0 3e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Golgin_A5 PF09787.9 KEY72761.1 - 0.00044 19.8 9.6 0.00074 19.1 9.6 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 ADIP PF11559.8 KEY72761.1 - 0.0016 18.6 7.0 0.0028 17.8 7.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KEY72761.1 - 0.0027 18.2 7.1 0.0057 17.1 7.1 1.5 1 0 0 1 1 1 1 Fez1 TMF_TATA_bd PF12325.8 KEY72761.1 - 0.0031 17.7 14.8 0.13 12.5 14.6 2.9 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF3150 PF11348.8 KEY72761.1 - 0.0071 15.6 3.0 0.48 9.6 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3150) Csm1_N PF18504.1 KEY72761.1 - 0.0091 16.3 6.4 1.3 9.4 0.1 3.5 3 0 0 3 3 3 2 Csm1 N-terminal domain Cast PF10174.9 KEY72761.1 - 0.01 14.1 7.3 0.065 11.5 7.3 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone MPS2 PF17060.5 KEY72761.1 - 0.014 14.7 0.5 0.021 14.1 0.5 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 KEY72761.1 - 0.028 13.3 8.0 0.051 12.4 8.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein LidA_Long_CC PF18641.1 KEY72761.1 - 0.046 13.8 3.6 3.5 7.7 3.6 2.3 1 1 0 1 1 1 0 LidA long coiled-coil domain DUF4407 PF14362.6 KEY72761.1 - 0.076 12.4 9.8 0.15 11.4 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KEY72761.1 - 0.16 11.7 6.4 0.7 9.6 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 KEY72761.1 - 0.26 11.7 1.2 1.3 9.5 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KEY72761.1 - 0.62 10.3 21.5 0.57 10.4 8.2 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 KEY72761.1 - 0.62 9.8 4.2 0.44 10.3 2.0 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain OmpH PF03938.14 KEY72761.1 - 0.86 9.9 9.7 1.2 9.5 8.0 2.1 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KEY72761.1 - 2.1 8.2 8.8 6.1 6.7 2.6 2.5 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 KEY72761.1 - 2.5 7.1 6.9 4.3 6.3 6.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 KEY72761.1 - 2.9 7.9 8.5 3.6 7.7 2.3 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 KEY72761.1 - 3.1 8.5 6.4 8.9 7.0 1.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Cep57_MT_bd PF06657.13 KEY72761.1 - 5.5 7.5 8.5 2.6 8.6 1.4 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAM76 PF16046.5 KEY72761.1 - 8.4 5.6 6.8 16 4.7 6.8 1.5 1 0 0 1 1 1 0 FAM76 protein Menin PF05053.13 KEY72762.1 - 2 6.7 5.7 2.1 6.6 5.7 1.1 1 0 0 1 1 1 0 Menin CorA PF01544.18 KEY72763.1 - 0.002 17.5 3.2 0.0035 16.7 3.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ATP_bind_3 PF01171.20 KEY72766.1 - 1.5e-40 138.9 0.0 3e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 PP-loop family TT1725 PF18324.1 KEY72767.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein TT1725 Herpes_pp85 PF04637.12 KEY72767.1 - 2.1 6.7 4.2 3.4 6.0 4.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4097 PF13349.6 KEY72768.1 - 0.00089 18.7 0.2 0.07 12.5 0.0 2.9 2 1 0 2 2 2 2 Putative adhesin Mito_carr PF00153.27 KEY72769.1 - 5.7e-69 228.1 4.6 2.6e-25 88.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KEY72769.1 - 1.6e-21 74.2 4.0 2.4e-06 26.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KEY72769.1 - 1.9e-19 69.8 2.6 4.5e-12 46.2 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEY72769.1 - 8.6e-17 59.6 3.7 3.8e-06 26.4 0.2 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KEY72769.1 - 1.7e-15 55.7 10.2 0.00021 20.7 0.2 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KEY72769.1 - 9e-11 41.5 6.6 0.0027 17.5 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KEY72769.1 - 1.2e-06 28.8 0.1 0.0021 18.4 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KEY72769.1 - 0.0023 17.8 0.3 2.8 7.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 KEY72769.1 - 0.016 15.1 1.8 3.4 7.7 0.1 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KEY72769.1 - 0.02 15.3 0.9 0.2 12.1 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain Serine_protease PF18405.1 KEY72769.1 - 0.022 13.9 1.6 1.5 7.9 0.1 3.4 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Cyclin_N PF00134.23 KEY72770.1 - 2.5e-12 46.6 0.8 3.3e-11 43.0 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KEY72770.1 - 0.00015 22.1 0.4 0.001 19.4 0.2 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Turandot PF07240.11 KEY72770.1 - 0.085 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Abhydrolase_1 PF00561.20 KEY72771.1 - 3.1e-12 46.7 0.1 4.5e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY72771.1 - 6.2e-11 42.0 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEY72771.1 - 1.1e-10 42.6 1.3 1.9e-10 41.7 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KEY72771.1 - 0.22 11.4 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KEY72771.1 - 0.36 10.9 1.5 0.54 10.3 0.9 1.5 2 0 0 2 2 2 0 Thioesterase domain APH PF01636.23 KEY72772.1 - 2.1e-06 27.9 0.0 4.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4452 PF14618.6 KEY72774.1 - 9.8e-76 253.3 13.8 1.2e-75 253.1 13.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Mito_carr PF00153.27 KEY72776.1 - 2.4e-42 142.8 8.5 6e-16 58.1 0.1 4.1 2 1 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KEY72776.1 - 0.0044 16.2 0.3 0.054 12.7 0.1 2.1 2 0 0 2 2 2 1 Gammaproteobacterial serine protease DUF3337 PF11816.8 KEY72777.1 - 2.5e-56 190.2 0.1 1.5e-55 187.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KEY72777.1 - 1.7e-17 63.5 9.7 0.0066 17.3 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KEY72777.1 - 0.0024 16.6 0.6 0.023 13.3 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF922 PF06037.11 KEY72777.1 - 0.16 11.7 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) KH_1 PF00013.29 KEY72778.1 - 1e-47 159.8 14.3 3.4e-17 62.0 1.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEY72778.1 - 1.4e-11 44.1 1.8 0.025 14.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEY72778.1 - 7.7e-09 35.3 6.2 0.023 14.5 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KEY72778.1 - 0.00067 19.6 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KEY72778.1 - 0.0032 17.5 3.7 4.6 7.4 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain DUF829 PF05705.14 KEY72780.1 - 7.9e-39 134.0 0.0 9.4e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Asp PF00026.23 KEY72781.1 - 1.7e-38 132.8 0.0 2.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KEY72781.1 - 0.00057 20.5 0.0 0.95 10.2 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KEY72781.1 - 0.013 15.3 0.0 0.058 13.2 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KEY72781.1 - 1 9.6 3.3 2.1 8.5 2.0 2.3 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal 6PF2K PF01591.18 KEY72782.1 - 9.4e-79 263.8 0.1 1.3e-78 263.4 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEY72782.1 - 5.2e-34 117.7 0.0 7.9e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KEY72782.1 - 3.6e-07 30.4 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEY72782.1 - 8.5e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AA_permease_2 PF13520.6 KEY72784.1 - 6.3e-05 22.0 0.0 6.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Amino acid permease CBF_beta PF02312.17 KEY72784.1 - 0.005 16.5 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 Core binding factor beta subunit Sterol-sensing PF12349.8 KEY72785.1 - 0.017 14.9 1.4 0.029 14.2 1.4 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation TMIE PF16038.5 KEY72785.1 - 0.34 10.8 1.2 0.62 9.9 1.2 1.3 1 0 0 1 1 1 0 TMIE protein Ank_2 PF12796.7 KEY72786.1 - 5.1e-79 260.9 25.3 4.7e-13 49.5 2.1 10.0 5 4 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY72786.1 - 3.8e-54 180.4 15.2 3.7e-08 33.7 0.0 14.6 10 3 6 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY72786.1 - 5.6e-46 149.2 21.2 0.0012 19.2 0.1 18.8 19 0 0 19 19 19 8 Ankyrin repeat Ank_5 PF13857.6 KEY72786.1 - 5.3e-34 115.8 32.5 3.7e-06 27.1 0.7 13.6 5 4 8 14 14 14 10 Ankyrin repeats (many copies) Ank PF00023.30 KEY72786.1 - 5.5e-34 115.1 48.0 0.00021 21.6 0.0 17.5 17 1 1 18 18 18 7 Ankyrin repeat Abhydrolase_6 PF12697.7 KEY72786.1 - 6.2e-07 30.2 5.1 3.8e-05 24.4 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72786.1 - 0.0004 19.7 0.0 0.00099 18.4 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_16 PF13191.6 KEY72786.1 - 0.00076 19.9 0.1 0.0051 17.2 0.1 2.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY72786.1 - 0.023 15.0 0.0 0.14 12.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain PRODH PF18327.1 KEY72786.1 - 0.1 12.8 0.2 6.8 7.0 0.0 3.3 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain PGAP1 PF07819.13 KEY72786.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KEY72786.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NAD_binding_4 PF07993.12 KEY72788.1 - 3.3e-34 118.2 0.0 4.9e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEY72788.1 - 7.6e-26 90.7 0.0 1.2e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEY72788.1 - 2.5e-08 34.1 0.0 6.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KEY72788.1 - 6.7e-06 25.7 0.0 1.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PS-DH PF14765.6 KEY72789.1 - 1.1e-50 172.5 0.4 2.2e-50 171.6 0.4 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KEY72789.1 - 9.1e-46 156.0 0.2 8.9e-45 152.8 0.0 2.7 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 KEY72789.1 - 4.6e-36 123.4 0.1 1.3e-35 121.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEY72789.1 - 1.3e-34 120.2 0.0 5.7e-34 118.0 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KEY72789.1 - 1.6e-22 80.3 0.0 1.6e-22 80.3 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 KEY72789.1 - 7.4e-16 58.6 0.0 2.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEY72789.1 - 1.2e-07 31.4 1.6 0.00072 19.1 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72789.1 - 0.00025 20.7 1.5 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KEY72789.1 - 0.00055 20.2 0.0 0.0038 17.6 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Glyco_trans_4_4 PF13579.6 KEY72789.1 - 0.0072 16.8 10.3 0.56 10.6 0.2 5.0 6 1 0 6 6 6 2 Glycosyl transferase 4-like domain ADH_zinc_N PF00107.26 KEY72789.1 - 0.03 14.3 0.1 0.49 10.4 0.0 2.8 3 0 0 3 3 3 0 Zinc-binding dehydrogenase YAcAr PF10686.9 KEY72789.1 - 0.042 13.8 0.4 0.13 12.2 0.4 1.8 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family GFO_IDH_MocA PF01408.22 KEY72790.1 - 5.8e-14 53.0 0.0 9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC2_membrane PF01061.24 KEY72791.1 - 2.6e-71 239.4 42.0 6.6e-36 123.7 16.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY72791.1 - 3.7e-33 114.9 0.0 3.4e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY72791.1 - 4.5e-25 87.4 2.7 3.1e-23 81.5 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEY72791.1 - 1.1e-07 31.3 27.5 0.00069 18.8 13.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KEY72791.1 - 2.7e-07 30.4 1.1 6.7e-05 22.5 0.4 3.3 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KEY72791.1 - 6.4e-05 23.4 4.0 0.0051 17.2 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KEY72791.1 - 6.5e-05 22.6 0.6 0.019 14.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY72791.1 - 0.00014 21.8 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KEY72791.1 - 0.00058 19.8 0.1 0.037 13.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY72791.1 - 0.0015 18.0 0.0 3.6 7.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEY72791.1 - 0.0021 18.0 0.4 0.18 11.7 0.0 2.8 3 0 0 3 3 2 1 NACHT domain ABC_trans_N PF14510.6 KEY72791.1 - 0.0021 18.6 0.0 0.0049 17.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_23 PF13476.6 KEY72791.1 - 0.004 17.7 0.0 0.0079 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY72791.1 - 0.0051 17.1 0.3 0.072 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEY72791.1 - 0.016 14.3 0.1 0.86 8.6 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KEY72791.1 - 0.018 14.7 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEY72791.1 - 0.023 14.8 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEY72791.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KEY72791.1 - 0.036 14.6 0.0 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEY72791.1 - 0.092 12.3 1.6 0.18 11.4 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KEY72791.1 - 0.18 11.7 0.0 5.3 6.9 0.1 2.9 3 0 0 3 3 3 0 NTPase Rad17 PF03215.15 KEY72791.1 - 0.23 11.4 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DDE_1 PF03184.19 KEY72792.1 - 9.3e-19 67.7 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KEY72792.1 - 0.019 14.7 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease ROKNT PF08067.11 KEY72792.1 - 0.08 13.2 2.3 0.19 12.1 2.3 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain SnoaL PF07366.12 KEY72793.1 - 9.8e-07 28.6 0.0 1.1e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY72793.1 - 7e-05 23.4 0.0 8.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain HSP20 PF00011.21 KEY72794.1 - 1.6e-10 41.1 1.2 2.3e-06 27.7 0.2 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Peptidase_S10 PF00450.22 KEY72796.1 - 1.8e-82 278.0 0.1 2.5e-82 277.6 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Egh16-like PF11327.8 KEY72797.1 - 3.4e-41 141.7 10.3 4.1e-41 141.4 10.3 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Glyco_transf_15 PF01793.16 KEY72799.1 - 4.8e-99 331.7 0.6 7.2e-99 331.1 0.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF953 PF06110.11 KEY72801.1 - 6.5e-17 61.3 0.0 7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KEY72801.1 - 0.0026 17.6 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin MID_pPIWI_RE PF18157.1 KEY72801.1 - 0.026 14.8 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 MID domain of pPIWI_RE Exo_endo_phos PF03372.23 KEY72802.1 - 4.4e-08 32.9 0.0 1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 3HCDH_N PF02737.18 KEY72803.1 - 1.9e-25 89.8 0.0 3.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEY72803.1 - 5e-22 78.3 0.0 1.2e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 KEY72803.1 - 7.7e-05 22.4 0.0 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KEY72803.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 KEY72803.1 - 0.063 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 KEY72803.1 - 0.064 13.8 0.1 0.17 12.5 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEY72803.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KEY72803.1 - 0.16 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KEY72805.1 - 2.7e-36 125.3 35.1 3.6e-36 124.8 35.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4267 PF14087.6 KEY72806.1 - 3.1e-14 53.0 1.0 3.8e-14 52.7 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Glyco_hydro_3_C PF01915.22 KEY72807.1 - 9e-50 169.5 0.1 1.3e-49 168.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY72807.1 - 6.8e-33 114.4 0.0 1.3e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY72807.1 - 1.5e-25 89.1 0.0 2.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Yippee-Mis18 PF03226.14 KEY72809.1 - 1.8e-11 44.2 0.1 2.4e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KEY72809.1 - 0.00067 19.9 0.1 0.00092 19.4 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 KEY72809.1 - 0.0021 17.9 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 HNH endonuclease HECT_2 PF09814.9 KEY72809.1 - 0.036 12.9 0.1 0.15 10.8 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Endonuclease_7 PF02945.15 KEY72809.1 - 0.045 13.7 1.2 0.11 12.4 1.2 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII GFA PF04828.14 KEY72810.1 - 6e-10 39.3 0.3 6e-10 39.3 0.3 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PQ-loop PF04193.14 KEY72811.1 - 1e-20 73.2 7.4 2.4e-17 62.4 0.1 3.2 3 0 0 3 3 3 2 PQ loop repeat VMA21 PF09446.10 KEY72811.1 - 0.021 14.9 1.0 1.3 9.2 0.1 2.8 2 1 0 2 2 2 0 VMA21-like domain Arteri_Gl PF00951.18 KEY72811.1 - 0.064 13.1 3.1 0.041 13.7 1.0 1.7 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein BPD_transp_2 PF02653.16 KEY72811.1 - 0.97 8.5 13.7 0.74 8.9 12.1 1.7 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF3995 PF13160.6 KEY72811.1 - 1.7 9.0 11.8 0.53 10.6 5.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Aldose_epim PF01263.20 KEY72813.1 - 1.3e-47 162.6 0.2 1.5e-47 162.4 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase VIT PF08487.10 KEY72814.1 - 7.9e-30 103.3 0.0 1.6e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KEY72814.1 - 1.3e-26 93.4 0.0 2.3e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEY72814.1 - 5.5e-10 39.8 0.0 9.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEY72814.1 - 4.5e-08 33.7 0.0 8.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KEY72814.1 - 1.7e-07 31.0 0.0 5.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain CDC45 PF02724.14 KEY72814.1 - 0.022 13.1 2.3 0.035 12.4 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein VWA_CoxE PF05762.14 KEY72814.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Nop14 PF04147.12 KEY72814.1 - 0.37 9.0 7.1 0.71 8.0 7.1 1.4 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane PF01061.24 KEY72816.1 - 1.5e-81 272.9 69.0 1.7e-42 145.2 26.3 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KEY72816.1 - 4e-36 124.6 0.0 7.8e-18 65.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY72816.1 - 2.5e-33 113.8 13.1 3.7e-27 94.0 0.2 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY72816.1 - 2.5e-12 47.2 3.8 3.9e-11 43.4 3.8 2.6 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KEY72816.1 - 4.7e-08 32.8 0.0 3.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEY72816.1 - 2.7e-06 27.6 0.6 0.0048 17.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEY72816.1 - 9.6e-06 26.1 0.1 0.0017 18.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KEY72816.1 - 3.1e-05 24.5 0.0 0.0093 16.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KEY72816.1 - 5.7e-05 23.1 0.1 0.0047 16.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEY72816.1 - 0.00075 19.2 0.8 0.053 13.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KEY72816.1 - 0.02 14.6 1.4 1.7 8.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEY72816.1 - 0.039 14.0 0.9 15 5.7 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase SMC_N PF02463.19 KEY72816.1 - 0.041 13.3 0.0 0.89 8.9 0.0 2.7 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KEY72816.1 - 0.044 12.9 59.0 0.14 11.2 9.2 4.4 3 1 0 3 3 3 0 ABC-2 family transporter protein AAA_21 PF13304.6 KEY72816.1 - 0.052 13.3 0.3 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEY72816.1 - 0.11 12.7 1.0 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEY72816.1 - 0.19 12.1 0.4 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEY72816.1 - 0.27 11.1 1.9 3.6 7.5 0.3 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KEY72816.1 - 4.7 6.8 5.1 0.78 9.3 0.7 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NAD_binding_8 PF13450.6 KEY72817.1 - 1.4e-12 47.7 0.2 3.8e-12 46.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY72817.1 - 1.6e-08 34.5 0.8 7.8e-07 29.0 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72817.1 - 6.2e-07 28.9 0.1 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEY72817.1 - 1e-05 25.0 0.1 0.0099 15.2 0.0 2.9 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEY72817.1 - 2.7e-05 24.6 0.0 0.18 12.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY72817.1 - 0.00011 21.4 0.1 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEY72817.1 - 0.00024 21.1 0.0 0.0021 18.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY72817.1 - 0.00026 19.8 0.0 0.025 13.3 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KEY72817.1 - 0.0052 16.1 0.0 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY72817.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEY72817.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KEY72817.1 - 0.03 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KEY72817.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KEY72817.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.17 KEY72818.1 - 6.3e-43 147.1 5.7 1.1e-42 146.3 5.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 FA_hydroxylase PF04116.13 KEY72819.1 - 1.2e-22 80.6 23.3 2.4e-21 76.5 22.0 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KEY72820.1 - 1.9e-37 129.0 17.1 4e-36 124.7 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEY72820.1 - 0.00029 20.3 6.9 0.00029 20.3 6.9 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4470 PF14737.6 KEY72821.1 - 2.1e-23 82.3 0.2 4.8e-23 81.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Acetyltransf_1 PF00583.25 KEY72821.1 - 3.8e-11 43.3 0.0 7.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-MYND PF01753.18 KEY72821.1 - 1e-07 31.9 13.3 1.8e-07 31.1 13.3 1.4 1 0 0 1 1 1 1 MYND finger Acetyltransf_7 PF13508.7 KEY72821.1 - 2e-07 31.3 0.0 4.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY72821.1 - 2.7e-07 30.6 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEY72821.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KEY72821.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KEY72821.1 - 0.037 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY72821.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-HIT PF04438.16 KEY72821.1 - 0.38 10.7 8.5 0.82 9.6 8.5 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KEY72821.1 - 0.67 10.3 8.4 1.4 9.2 8.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Glyco_hydro_67M PF07488.12 KEY72822.1 - 1.5e-143 477.8 0.0 2.1e-143 477.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KEY72822.1 - 1.9e-89 299.1 1.8 3e-89 298.4 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KEY72822.1 - 2.2e-28 99.0 0.0 5.7e-28 97.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KEY72822.1 - 0.0025 18.6 0.1 0.012 16.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 ADH_zinc_N PF00107.26 KEY72823.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY72823.1 - 0.0016 18.3 0.0 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.8 KEY72824.1 - 0.009 14.9 0.2 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72824.1 - 0.011 15.8 2.3 0.011 15.8 2.3 2.3 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 KEY72825.1 - 1.3e-93 313.8 1.6 1.5e-93 313.6 1.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KEY72825.1 - 0.0029 16.2 0.5 0.0041 15.7 0.5 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MiaE PF06175.11 KEY72825.1 - 0.094 12.3 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Glyco_hydro_76 PF03663.14 KEY72825.1 - 0.99 8.8 7.3 0.34 10.4 1.6 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KEY72826.1 - 5.6e-33 114.3 14.7 8.5e-33 113.7 14.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72826.1 - 6.4e-10 38.5 0.7 6.4e-10 38.5 0.7 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KEY72826.1 - 0.00029 19.4 3.9 0.0018 16.8 1.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Folate_carrier PF01770.18 KEY72826.1 - 0.013 14.3 0.1 0.024 13.4 0.1 1.6 1 1 0 1 1 1 0 Reduced folate carrier MFS_1 PF07690.16 KEY72827.1 - 2e-49 168.4 36.4 2e-49 168.4 36.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY72827.1 - 5.4e-11 42.0 24.4 1.7e-10 40.4 24.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KEY72827.1 - 0.23 9.8 11.3 0.018 13.5 5.9 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector YecM PF06185.12 KEY72828.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 YecM protein F-box-like PF12937.7 KEY72829.1 - 0.00027 20.8 3.1 0.00034 20.4 1.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KEY72829.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like domain Methyltransf_15 PF09445.10 KEY72829.1 - 0.049 13.2 0.0 0.34 10.5 0.0 2.3 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase Fzo_mitofusin PF04799.13 KEY72829.1 - 0.24 11.0 0.4 0.47 10.0 0.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4200 PF13863.6 KEY72829.1 - 0.24 11.8 2.5 0.45 10.9 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) 2OG-FeII_Oxy_3 PF13640.6 KEY72832.1 - 3e-10 40.9 0.1 5.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4612 PF15389.6 KEY72834.1 - 0.062 14.3 0.0 0.14 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) FlgM PF04316.13 KEY72834.1 - 2.2 8.7 4.5 4.6 7.7 4.5 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM CBM_4_9 PF02018.17 KEY72835.1 - 2.1e-07 31.3 0.0 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain Pyr_redox_2 PF07992.14 KEY72836.1 - 2.1e-10 40.3 0.0 2e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY72836.1 - 3.3e-07 29.1 0.0 8e-07 27.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY72836.1 - 2.9e-05 23.5 0.1 0.00087 18.6 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY72836.1 - 4.3e-05 22.8 0.0 0.00067 18.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY72836.1 - 5.2e-05 23.3 0.1 0.045 13.8 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEY72836.1 - 9.6e-05 22.5 0.2 0.0041 17.3 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY72836.1 - 0.00019 21.9 0.0 0.051 14.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEY72836.1 - 0.0033 17.5 0.0 0.36 10.9 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KEY72836.1 - 0.13 11.6 0.2 9.6 5.5 0.1 2.2 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.19 KEY72836.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KEY72836.1 - 0.36 10.4 3.0 8.4 5.9 0.1 3.5 3 2 1 5 5 5 0 FAD dependent oxidoreductase DJ-1_PfpI PF01965.24 KEY72837.1 - 3.2e-08 33.5 0.0 3.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family BTB PF00651.31 KEY72838.1 - 6e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Laminin_G_3 PF13385.6 KEY72839.1 - 1.3e-06 28.6 0.5 2e-06 28.0 0.5 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.21 KEY72839.1 - 0.0018 17.7 0.1 0.0028 17.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.24 KEY72839.1 - 0.1 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Laminin G domain Epimerase PF01370.21 KEY72840.1 - 1.4e-13 50.9 0.0 3.1e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY72840.1 - 4.9e-09 35.6 0.0 8.9e-09 34.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEY72840.1 - 1.3e-08 34.7 0.1 2.9e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEY72840.1 - 1.7e-08 34.6 0.0 4.4e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEY72840.1 - 7.9e-06 25.2 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KEY72840.1 - 0.00046 19.8 0.1 0.00071 19.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KEY72840.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase PF01425.21 KEY72842.1 - 2.1e-32 112.7 0.0 3.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Amidase FA_desaturase PF00487.24 KEY72843.1 - 1.1e-29 104.1 21.3 1.8e-29 103.4 21.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEY72843.1 - 5.7e-09 36.0 0.0 1.4e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Coq4 PF05019.13 KEY72843.1 - 0.043 13.1 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Inositol_P PF00459.25 KEY72844.1 - 8.8e-77 258.3 0.0 1.2e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Ribonuc_L-PSP PF01042.21 KEY72844.1 - 6.9e-35 119.7 0.0 1.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FYVE_2 PF02318.16 KEY72845.1 - 0.0016 18.6 0.3 0.0021 18.2 0.3 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger CHORD PF04968.12 KEY72845.1 - 1.1 10.0 9.0 0.34 11.7 0.8 2.7 2 1 0 2 2 2 0 CHORD OsmC PF02566.19 KEY72846.1 - 2.9e-18 66.2 0.2 4.9e-18 65.4 0.1 1.4 2 0 0 2 2 2 1 OsmC-like protein Cpn10 PF00166.21 KEY72846.1 - 0.048 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit CBM_15 PF03426.14 KEY72846.1 - 0.058 13.0 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Glyco_hydro_3_C PF01915.22 KEY72847.1 - 1.5e-44 152.4 0.0 3.5e-44 151.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY72847.1 - 7.9e-40 137.2 0.0 1.2e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY72847.1 - 2.1e-26 91.8 0.6 3.7e-26 91.0 0.6 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MbeD_MobD PF04899.12 KEY72849.1 - 0.0053 16.9 1.1 0.11 12.6 0.2 2.9 2 0 0 2 2 2 1 MbeD/MobD like Helo_like_N PF17111.5 KEY72849.1 - 0.019 14.4 0.1 0.049 13.0 0.1 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins GBR_NSP5 PF17580.2 KEY72849.1 - 0.054 13.3 0.3 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Big_3_2 PF12245.8 KEY72849.1 - 0.12 12.6 0.4 1.7 9.0 0.1 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain CorA PF01544.18 KEY72852.1 - 7.4e-07 28.8 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Inhibitor_I36 PF03995.13 KEY72852.1 - 0.044 13.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DUF3784 PF12650.7 KEY72853.1 - 2.4 8.4 4.9 21 5.4 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) SPC12 PF06645.13 KEY72853.1 - 9.7 6.4 6.2 3 8.0 0.4 2.7 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_S14 PF00253.21 KEY72854.1 - 4.6e-22 77.5 0.6 4.6e-22 77.5 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Synaphin PF05835.12 KEY72854.1 - 0.11 12.7 1.3 0.14 12.4 1.3 1.2 1 0 0 1 1 1 0 Synaphin protein CWC25 PF12542.8 KEY72855.1 - 1.8e-26 93.0 1.4 1.8e-26 93.0 1.4 4.3 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KEY72855.1 - 4.9e-12 45.8 2.1 4.9e-12 45.8 2.1 5.1 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Aldedh PF00171.22 KEY72856.1 - 1.4e-130 436.0 0.1 1.5e-130 435.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPW PF03779.14 KEY72856.1 - 4.3 7.0 6.0 0.49 10.0 0.7 2.2 3 0 0 3 3 3 0 SPW repeat TPP_enzyme_N PF02776.18 KEY72858.1 - 1.5e-40 138.6 1.5 4.4e-37 127.3 1.3 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEY72858.1 - 1.9e-17 63.5 0.0 3.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY72858.1 - 7e-12 45.2 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_3 PF01494.19 KEY72859.1 - 1.7e-20 73.6 0.3 4e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEY72859.1 - 3.5e-07 30.1 4.3 0.0081 15.8 1.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY72859.1 - 9.1e-07 28.4 1.5 0.0004 19.7 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY72859.1 - 4.5e-06 26.0 0.1 6.6e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY72859.1 - 6.2e-06 26.4 1.1 4.9e-05 23.5 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY72859.1 - 2e-05 23.9 0.4 4.1e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY72859.1 - 0.0044 15.8 0.4 0.049 12.3 0.9 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KEY72859.1 - 0.011 14.8 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KEY72859.1 - 0.014 14.2 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 KEY72859.1 - 0.015 14.7 0.3 0.094 12.0 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KEY72859.1 - 0.037 13.3 1.0 0.064 12.5 0.5 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KEY72859.1 - 0.11 13.0 0.1 0.37 11.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY72859.1 - 0.28 10.4 0.6 0.45 9.7 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KEY72861.1 - 1.1e-36 126.5 31.5 1.6e-36 126.0 31.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KEY72862.1 - 1.2e-16 60.5 0.0 2.1e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72862.1 - 0.065 13.4 14.7 0.12 12.6 14.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.6 KEY72862.1 - 0.38 8.6 4.9 0.58 8.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Abhydrolase_1 PF00561.20 KEY72863.1 - 1.7e-19 70.5 1.4 5.6e-18 65.5 1.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY72863.1 - 1e-14 55.7 3.2 1.2e-14 55.4 3.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY72863.1 - 7e-14 51.7 0.1 1.6e-13 50.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY72863.1 - 3.1e-06 26.1 0.0 3.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KEY72863.1 - 0.079 12.9 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4360 PF14273.6 KEY72864.1 - 4.7e-66 222.1 3.9 5.3e-66 221.9 3.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_16 PF00722.21 KEY72865.1 - 5.3e-38 130.2 0.2 8.9e-38 129.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 T2SSM PF04612.12 KEY72865.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Lip_prot_lig_C PF10437.9 KEY72865.1 - 0.23 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Trypan_PARP PF05887.11 KEY72866.1 - 0.029 14.3 8.6 0.053 13.5 8.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4472 PF14739.6 KEY72866.1 - 0.043 14.6 1.3 0.062 14.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Ras PF00071.22 KEY72867.1 - 7.8e-50 168.6 0.0 1.9e-25 89.3 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEY72867.1 - 1.1e-17 64.4 0.0 1.2e-15 57.7 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY72867.1 - 0.00014 21.3 0.0 0.00071 19.1 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KEY72867.1 - 0.0084 15.3 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KEY72867.1 - 0.0095 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY72867.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KEY72867.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.6 1 1 1 2 2 2 0 ABC transporter SRPRB PF09439.10 KEY72867.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HATPase_c PF02518.26 KEY72868.1 - 4.9e-21 75.3 0.0 1.1e-20 74.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY72868.1 - 4.9e-18 65.3 0.1 1.4e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KEY72868.1 - 6.3e-09 35.7 0.1 1.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KEY72868.1 - 0.042 14.2 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 GAF domain Citrate_synt PF00285.21 KEY72869.1 - 4.3e-99 332.0 0.0 5.3e-99 331.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 KEY72870.1 - 3.2e-195 649.6 0.1 3.9e-195 649.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Abhydrolase_1 PF00561.20 KEY72871.1 - 5.4e-45 154.1 0.0 1.1e-44 153.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KEY72871.1 - 0.003 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KEY72871.1 - 0.011 15.6 0.4 0.045 13.6 0.2 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase zf-RING_6 PF14835.6 KEY72871.1 - 0.051 13.5 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein NUDIX PF00293.28 KEY72873.1 - 2.1e-07 31.1 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KEY72874.1 - 5.6e-15 55.5 0.2 1.2e-14 54.5 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain MFS_1 PF07690.16 KEY72875.1 - 1.1e-18 67.3 30.6 1.1e-18 67.3 30.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KEY72875.1 - 0.00014 20.3 0.7 0.00025 19.5 0.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PCI PF01399.27 KEY72876.1 - 1.9e-17 63.7 0.5 5.9e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KEY72876.1 - 0.054 13.6 3.7 0.21 11.8 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4404 PF14357.6 KEY72876.1 - 0.077 13.6 0.1 9.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_11 PF13414.6 KEY72876.1 - 0.13 12.0 1.2 0.72 9.6 0.3 2.6 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KEY72876.1 - 0.23 11.6 1.2 5 7.4 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY72876.1 - 0.23 11.3 3.4 1 9.3 0.6 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY72876.1 - 6.2 7.7 7.0 1.8 9.4 0.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KEY72877.1 - 2e-05 24.6 9.9 3.5e-05 23.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_N PF04675.14 KEY72879.1 - 7.8e-15 55.6 0.0 1.3e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KEY72879.1 - 1.2e-11 44.6 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain TolA PF06519.11 KEY72879.1 - 0.037 14.2 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 TolA C-terminal Antimicrobial_2 PF08023.12 KEY72879.1 - 0.06 13.9 1.8 0.15 12.6 1.8 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide RNA_ligase PF09414.10 KEY72879.1 - 0.074 13.4 0.0 1 9.7 0.0 2.3 1 1 0 1 1 1 0 RNA ligase Methyltransf_23 PF13489.6 KEY72880.1 - 9.3e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY72880.1 - 1e-11 45.4 0.0 3.7e-11 43.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY72880.1 - 1.6e-08 35.2 0.0 1.3e-07 32.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72880.1 - 3.7e-08 33.9 0.0 2.8e-07 31.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72880.1 - 2.8e-06 27.2 0.0 2.2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEY72880.1 - 0.0012 18.2 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_16 PF10294.9 KEY72880.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KEY72880.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KEY72880.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KEY72880.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KEY72880.1 - 0.039 13.3 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KEY72880.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Clr5 PF14420.6 KEY72883.1 - 5e-12 45.9 0.1 8.8e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain ArnB_C PF18677.1 KEY72886.1 - 0.0013 18.8 0.2 0.002 18.2 0.2 1.3 1 0 0 1 1 1 1 Archaellum regulatory network B, C-terminal domain LPP20 PF02169.16 KEY72886.1 - 0.006 16.9 0.9 0.0079 16.5 0.9 1.2 1 0 0 1 1 1 1 LPP20 lipoprotein Sec34 PF04136.15 KEY72886.1 - 0.0074 16.2 0.2 0.01 15.8 0.2 1.3 1 0 0 1 1 1 1 Sec34-like family Mt_ATP-synt_B PF05405.14 KEY72886.1 - 0.019 14.6 0.4 0.027 14.1 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) HAUS6_N PF14661.6 KEY72886.1 - 0.035 13.7 0.2 0.041 13.5 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Rep_fac-A_3 PF08661.11 KEY72886.1 - 0.076 13.4 0.2 0.15 12.5 0.2 1.6 1 1 0 1 1 1 0 Replication factor A protein 3 NAD_binding_1 PF00175.21 KEY72888.1 - 0.00013 22.6 0.1 0.41 11.3 0.0 2.8 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEY72888.1 - 0.0018 18.4 0.0 0.0038 17.4 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DsbC PF11412.8 KEY72888.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC APG6_N PF17675.1 KEY72889.1 - 1.9 9.0 13.8 3.2 8.3 12.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Fungal_trans PF04082.18 KEY72890.1 - 5.9e-07 28.8 0.5 1.3e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72890.1 - 0.0088 16.2 0.8 0.022 14.9 0.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3435 PF11917.8 KEY72891.1 - 2e-26 92.9 2.0 2.6e-26 92.5 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.23 KEY72893.1 - 6.4e-15 55.7 0.0 9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEY72893.1 - 0.0031 17.1 0.0 0.051 13.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KEY72893.1 - 0.0035 17.0 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF905 PF06006.12 KEY72893.1 - 0.028 14.4 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) SBP_bac_3 PF00497.20 KEY72893.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 HlyIII PF03006.20 KEY72895.1 - 1.2e-24 87.3 3.2 1.3e-24 87.1 3.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related Kelch_5 PF13854.6 KEY72896.1 - 7.6e-08 32.2 0.3 5.1e-07 29.5 0.1 2.6 2 0 0 2 2 2 1 Kelch motif CD99L2 PF12301.8 KEY72896.1 - 0.0058 17.0 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 CD99 antigen like protein 2 SKG6 PF08693.10 KEY72896.1 - 0.0088 15.4 0.6 0.018 14.5 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.6 KEY72896.1 - 0.15 12.4 5.0 65 4.0 0.1 4.9 5 0 0 5 5 5 0 Kelch motif Gram_pos_anchor PF00746.21 KEY72896.1 - 1.1 9.2 2.5 2.1 8.4 2.5 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Kelch_4 PF13418.6 KEY72896.1 - 6.4 6.9 10.8 2.8 8.0 0.1 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain HET PF06985.11 KEY72897.1 - 0.052 13.9 0.2 0.15 12.5 0.2 1.6 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) T5orf172 PF10544.9 KEY72898.1 - 1.2e-24 86.8 0.0 3.4e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KEY72898.1 - 3.7e-22 78.8 0.0 7.3e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Ndc1_Nup PF09531.10 KEY72898.1 - 8.4 4.9 6.8 11 4.6 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sod_Fe_C PF02777.18 KEY72900.1 - 3.9e-36 123.3 0.6 8.6e-36 122.2 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEY72900.1 - 2.9e-33 114.2 3.3 3.6e-33 113.9 1.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF89 PF01937.19 KEY72903.1 - 6.9e-128 426.5 0.0 7.9e-128 426.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 F-box PF00646.33 KEY72904.1 - 0.005 16.7 0.3 0.013 15.4 0.2 1.7 2 0 0 2 2 2 1 F-box domain JIP_LZII PF16471.5 KEY72905.1 - 2.1 8.6 12.1 1.2 9.4 3.6 2.7 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 KEY72906.1 - 4 7.3 8.7 0.49 10.2 2.1 2.6 2 0 0 2 2 2 0 Septum formation initiator Complex1_LYR PF05347.15 KEY72907.1 - 9.1e-06 25.6 0.2 1.1e-05 25.4 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY72907.1 - 8.5e-05 23.2 0.1 9.7e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.6 KEY72908.1 - 3.1e-13 50.2 0.0 5.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY72908.1 - 5.1e-08 32.9 0.0 8.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY72908.1 - 6.7e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY72908.1 - 2.4e-07 31.4 0.0 4.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72908.1 - 0.0048 16.7 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY72908.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Exo_endo_phos PF03372.23 KEY72909.1 - 2.7e-19 69.6 0.1 6.6e-18 65.1 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KEY72909.1 - 2.4e-10 40.5 9.6 1e-05 25.8 0.8 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY72909.1 - 4.1e-08 32.9 4.6 2.3e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KEY72909.1 - 0.15 12.7 1.6 30 5.7 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat Mito_carr PF00153.27 KEY72910.1 - 1.7e-16 59.9 0.0 1.9e-10 40.5 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein Radical_SAM_C PF16199.5 KEY72911.1 - 8e-32 109.1 0.0 1.5e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KEY72911.1 - 9.8e-17 61.8 0.1 3.2e-16 60.1 0.0 1.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KEY72911.1 - 7.5e-09 35.8 0.1 1.4e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY72911.1 - 0.0001 22.2 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY72911.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ligase_CoA PF00549.19 KEY72912.1 - 4.8e-24 84.9 0.6 8.7e-24 84.1 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KEY72912.1 - 1.3e-21 77.1 8.6 2.5e-21 76.1 4.0 2.9 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KEY72912.1 - 2.5e-10 40.3 0.1 4.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEY72912.1 - 0.0016 18.9 0.2 0.0056 17.2 0.1 2.0 2 1 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 KEY72913.1 - 4.9e-39 133.2 0.0 6.2e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KEY72913.1 - 5.7e-05 22.8 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KEY72913.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEY72913.1 - 0.072 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 UEV domain DUF3684 PF12449.8 KEY72913.1 - 0.23 9.2 0.0 0.31 8.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) AAA PF00004.29 KEY72914.1 - 2e-41 141.5 0.0 3.7e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEY72914.1 - 1e-11 44.6 0.3 2.2e-11 43.5 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEY72914.1 - 5.4e-11 42.1 0.4 1.1e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KEY72914.1 - 4.4e-06 26.9 0.0 9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEY72914.1 - 8.1e-06 26.2 0.1 0.0065 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEY72914.1 - 1.4e-05 24.4 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KEY72914.1 - 8.2e-05 22.6 0.1 0.00036 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEY72914.1 - 0.00037 20.9 0.1 0.0065 16.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEY72914.1 - 0.00045 20.0 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEY72914.1 - 0.0021 18.6 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEY72914.1 - 0.0026 18.0 0.3 0.0094 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KEY72914.1 - 0.0027 17.3 0.7 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 KEY72914.1 - 0.0098 15.1 0.2 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KEY72914.1 - 0.011 15.9 0.1 0.028 14.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KEY72914.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KEY72914.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KEY72914.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY72914.1 - 0.056 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KEY72914.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KEY72914.1 - 0.067 13.1 0.1 0.62 10.0 0.1 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KEY72914.1 - 0.078 12.3 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 KEY72914.1 - 0.081 12.4 3.2 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 KEY72914.1 - 0.095 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin WYL PF13280.6 KEY72914.1 - 0.11 12.5 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 WYL domain RNA_pol_Rpb1_5 PF04998.17 KEY72914.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2075 PF09848.9 KEY72914.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KEY72914.1 - 0.34 10.6 2.0 0.33 10.6 0.4 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEY72914.1 - 0.78 9.3 4.6 0.58 9.7 0.4 2.6 2 1 0 3 3 3 0 AAA domain Promethin PF16015.5 KEY72915.1 - 6.3e-33 112.9 21.0 7.3e-33 112.7 21.0 1.0 1 0 0 1 1 1 1 Promethin PAP2 PF01569.21 KEY72916.1 - 2.7e-22 79.0 6.3 2.7e-22 79.0 6.3 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF2418 PF10332.9 KEY72916.1 - 0.25 11.9 1.7 0.63 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF3744 PF12558.8 KEY72917.1 - 0.19 12.5 0.2 0.37 11.6 0.2 1.4 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter Dimerisation PF08100.11 KEY72917.1 - 0.19 11.8 0.0 0.5 10.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Glyco_hydro_72 PF03198.14 KEY72918.1 - 1.9e-114 382.2 0.1 2.5e-114 381.8 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KEY72918.1 - 7.4e-19 68.2 4.1 1.8e-18 67.0 4.1 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KEY72918.1 - 0.00052 19.5 0.5 0.0013 18.2 0.5 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEY72918.1 - 0.0029 16.8 0.1 0.0084 15.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Dehydrin PF00257.19 KEY72918.1 - 0.47 11.0 1.9 24 5.4 1.2 2.3 2 0 0 2 2 2 0 Dehydrin Pkinase PF00069.25 KEY72919.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.27 KEY72921.1 - 8.6e-48 162.3 0.0 1e-22 81.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KEY72921.1 - 2e-20 72.6 1.9 2e-20 72.6 1.9 2.5 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KEY72921.1 - 1.2e-18 68.0 1.2 0.00014 21.8 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY72921.1 - 1.8e-11 43.9 0.7 0.01 15.3 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEY72921.1 - 8.8e-09 35.0 0.1 0.0029 17.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEY72921.1 - 2.2e-08 34.9 1.6 0.019 15.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEY72921.1 - 5.6e-07 30.1 0.1 0.0051 17.2 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KEY72921.1 - 1.5e-06 28.2 0.7 0.04 13.6 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEY72921.1 - 3.6e-06 27.0 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEY72921.1 - 9.2e-06 25.7 0.0 0.027 14.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY72921.1 - 9.8e-06 25.9 0.0 0.091 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEY72921.1 - 1.7e-05 25.2 0.1 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEY72921.1 - 3.5e-05 24.2 0.0 0.25 11.7 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEY72921.1 - 4.3e-05 24.1 0.0 0.21 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KEY72921.1 - 8.5e-05 22.5 0.1 0.19 11.6 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 KEY72921.1 - 0.00011 22.2 0.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEY72921.1 - 0.00033 20.8 0.0 0.73 10.0 0.1 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KEY72921.1 - 0.00048 20.5 0.9 1.8 9.0 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_27 PF13514.6 KEY72921.1 - 0.00083 19.0 0.0 0.21 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KEY72921.1 - 0.00093 19.2 0.0 2.1 8.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain MCM PF00493.23 KEY72921.1 - 0.0011 18.1 0.1 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain NB-ARC PF00931.22 KEY72921.1 - 0.0015 17.8 0.2 5.4 6.1 0.0 3.5 4 0 0 4 4 4 0 NB-ARC domain AAA_17 PF13207.6 KEY72921.1 - 0.002 18.5 0.0 0.5 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KEY72921.1 - 0.0038 17.3 0.0 2.7 8.0 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_24 PF13479.6 KEY72921.1 - 0.0054 16.5 1.8 2 8.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KEY72921.1 - 0.0059 16.2 0.0 0.49 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KEY72921.1 - 0.0089 16.2 1.6 3.4 7.9 0.1 3.2 3 1 1 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KEY72921.1 - 0.016 15.0 0.2 1.8 8.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF2813 PF11398.8 KEY72921.1 - 0.019 14.2 0.6 3 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 KEY72921.1 - 0.025 14.1 0.0 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KEY72921.1 - 0.03 14.3 0.3 2.2 8.2 0.2 2.6 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 KEY72921.1 - 0.04 13.8 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KEY72921.1 - 0.046 12.9 0.2 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.9 KEY72921.1 - 0.076 12.2 0.2 5.3 6.1 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.9 KEY72921.1 - 0.082 11.7 0.2 16 4.1 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 KEY72921.1 - 0.097 12.8 0.8 28 4.7 0.0 3.2 4 0 0 4 4 2 0 Helicase HerA, central domain FeoB_N PF02421.18 KEY72921.1 - 0.1 12.1 0.1 9.1 5.8 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B TsaE PF02367.17 KEY72921.1 - 0.17 11.9 0.6 33 4.5 0.0 3.2 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KEY72921.1 - 0.2 11.9 0.9 16 5.8 0.1 3.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF3405 PF11885.8 KEY72922.1 - 2.2e-133 445.6 0.8 3.1e-133 445.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SNF2_N PF00176.23 KEY72923.1 - 3.3e-64 216.8 0.7 6.2e-64 215.9 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KEY72923.1 - 3.3e-48 163.5 16.8 3.3e-48 163.5 16.8 6.0 5 2 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.31 KEY72923.1 - 6e-20 71.7 0.0 1.4e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY72923.1 - 6.5e-07 29.5 0.0 6.5e-07 29.5 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KEY72923.1 - 0.054 12.7 0.0 0.054 12.7 0.0 3.2 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 KEY72923.1 - 3.5 7.2 7.7 0.16 11.6 1.5 1.9 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain zf-C2H2_11 PF16622.5 KEY72924.1 - 0.075 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KEY72924.1 - 0.2 12.2 0.0 0.2 12.2 0.0 4.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY72924.1 - 0.23 12.4 0.0 0.23 12.4 0.0 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 KEY72924.1 - 5.7 7.5 6.0 15 6.2 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MatE PF01554.18 KEY72925.1 - 2.8e-10 40.1 14.5 2.4e-05 24.1 0.3 3.5 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KEY72925.1 - 0.0072 16.4 0.4 0.0072 16.4 0.4 4.2 3 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TrkH PF02386.16 KEY72927.1 - 2.9e-123 412.0 2.0 2.9e-123 412.0 2.0 1.5 2 0 0 2 2 2 1 Cation transport protein DUF2828 PF11443.8 KEY72930.1 - 0.0092 14.1 4.3 0.011 13.8 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RRN3 PF05327.11 KEY72930.1 - 0.11 11.0 1.0 0.15 10.6 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ARGLU PF15346.6 KEY72930.1 - 0.19 11.6 32.5 0.41 10.5 32.5 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Peptidase_S64 PF08192.11 KEY72930.1 - 0.26 9.7 2.9 0.33 9.4 2.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Radial_spoke_3 PF06098.11 KEY72930.1 - 0.53 9.5 20.8 1.1 8.5 20.8 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Plasmodium_Vir PF05795.11 KEY72930.1 - 0.69 9.3 2.7 1 8.7 2.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ACCA PF03255.14 KEY72930.1 - 0.89 9.4 10.7 1.7 8.5 10.7 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CPSF100_C PF13299.6 KEY72930.1 - 1.5 9.0 8.5 2.6 8.2 8.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2058 PF09831.9 KEY72930.1 - 1.9 8.6 13.4 3.4 7.8 13.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Menin PF05053.13 KEY72930.1 - 2.2 6.6 6.2 2.9 6.2 6.2 1.1 1 0 0 1 1 1 0 Menin DUF4770 PF15994.5 KEY72930.1 - 2.6 8.3 8.4 5.6 7.2 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Borrelia_P83 PF05262.11 KEY72930.1 - 2.7 6.4 12.7 3.8 5.9 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF913 PF06025.12 KEY72930.1 - 3 6.7 5.7 8.6 5.2 5.9 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GBP_C PF02841.14 KEY72930.1 - 3.8 6.8 19.9 7.1 5.9 19.9 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Connexin PF00029.19 KEY72930.1 - 4.6 6.9 7.8 7.5 6.2 7.8 1.2 1 0 0 1 1 1 0 Connexin RP-C_C PF11800.8 KEY72930.1 - 7.7 6.6 14.0 5.1 7.1 11.7 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF874 PF05917.11 KEY72930.1 - 9.5 5.1 14.5 15 4.5 14.5 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) TPR_10 PF13374.6 KEY72933.1 - 1.3e-18 66.2 0.2 1.8e-09 37.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEY72933.1 - 8.7e-17 61.2 0.4 2.9e-08 33.9 0.0 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 KEY72933.1 - 1.3e-10 40.9 0.0 3.1e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain PNP_UDP_1 PF01048.20 KEY72933.1 - 1.9e-07 30.6 0.1 6.6e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.6 KEY72933.1 - 2e-05 24.3 1.0 0.0089 16.0 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.12 KEY72933.1 - 0.00039 20.4 0.1 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain TPR_17 PF13431.6 KEY72933.1 - 0.011 16.0 0.0 0.95 10.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY72933.1 - 0.03 14.4 0.0 6.9 7.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEY72933.1 - 0.24 11.3 0.6 4.1 7.4 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 KEY72934.1 - 5.3e-24 84.8 59.8 4.5e-21 75.2 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KEY72935.1 - 2.6e-19 69.7 2.1 2.2e-18 66.7 2.1 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY72935.1 - 9.8e-07 28.7 0.5 2.2e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY72935.1 - 9.7e-05 22.5 0.1 0.00025 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY72935.1 - 0.0004 19.6 0.0 0.00064 18.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEY72935.1 - 0.00073 20.0 0.2 0.0033 18.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEY72935.1 - 0.0013 17.8 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Thi4 PF01946.17 KEY72935.1 - 0.0018 17.6 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEY72935.1 - 0.002 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY72935.1 - 0.025 13.7 0.0 0.051 12.6 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEY72935.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY72935.1 - 0.13 10.9 0.8 0.2 10.3 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.21 KEY72936.1 - 6.4e-12 45.4 0.0 9.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY72936.1 - 1.4e-08 34.1 0.0 1.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY72936.1 - 6.7e-08 32.0 0.0 9.6e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KEY72936.1 - 0.0067 15.6 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEY72936.1 - 0.0078 15.6 0.1 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase ELMO_CED12 PF04727.13 KEY72936.1 - 0.024 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 ELMO/CED-12 family FSH1 PF03959.13 KEY72937.1 - 3.9e-31 108.4 0.0 5e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KEY72937.1 - 0.017 14.9 0.1 0.051 13.4 0.0 1.7 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase NAD_binding_8 PF13450.6 KEY72938.1 - 2.5e-12 46.8 0.0 2.4e-11 43.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY72938.1 - 1.2e-07 31.4 0.2 1.8e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEY72938.1 - 8.6e-07 28.6 0.0 3.2e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KEY72938.1 - 1.5e-06 27.6 1.4 2.1e-06 27.1 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY72938.1 - 2.8e-06 26.3 1.4 4e-06 25.8 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEY72938.1 - 0.00026 20.4 0.9 0.00038 19.8 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY72938.1 - 0.00033 20.0 0.0 0.0006 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY72938.1 - 0.00083 19.9 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY72938.1 - 0.0024 17.5 1.0 0.0036 16.9 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY72938.1 - 0.0042 16.4 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KEY72938.1 - 0.006 16.2 0.4 0.011 15.3 0.1 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 KEY72938.1 - 0.0089 15.1 0.6 0.013 14.6 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KEY72938.1 - 0.013 14.7 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEY72938.1 - 0.39 9.5 0.8 0.55 9.0 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF1877 PF08974.10 KEY72939.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) adh_short PF00106.25 KEY72939.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF3632 PF12311.8 KEY72940.1 - 3.4e-25 89.5 3.4 4.3e-25 89.1 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) TENA_THI-4 PF03070.16 KEY72941.1 - 0.0025 17.6 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 TENA/THI-4/PQQC family MFS_1 PF07690.16 KEY72942.1 - 2e-32 112.5 65.2 6e-25 87.9 37.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY72942.1 - 0.0021 16.5 21.2 0.0061 15.0 5.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3149 PF11346.8 KEY72942.1 - 0.089 12.4 5.2 0.43 10.2 5.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Transketolase_N PF00456.21 KEY72943.1 - 1.8e-125 418.4 0.1 5.9e-125 416.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEY72943.1 - 4.3e-37 127.5 0.0 9.1e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 KEY72943.1 - 2.7e-07 30.1 0.0 4.3e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 KEY72943.1 - 2.8e-07 30.4 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KEY72943.1 - 3.5e-05 22.9 0.2 6.1e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component F_bP_aldolase PF01116.20 KEY72944.1 - 1.1e-74 251.5 0.0 1.2e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C34 PF05413.11 KEY72944.1 - 0.07 13.4 0.0 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase Fungal_trans_2 PF11951.8 KEY72945.1 - 6e-11 41.8 0.0 9.3e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY72945.1 - 5.6e-08 32.8 10.9 1e-07 31.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAS_I_H PF18314.1 KEY72945.1 - 0.12 12.0 0.5 0.26 10.9 0.5 1.5 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain CCAP PF11105.8 KEY72945.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a adh_short_C2 PF13561.6 KEY72946.1 - 2.1e-52 178.0 0.0 2.6e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY72946.1 - 2.9e-49 167.2 0.2 3.7e-49 166.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY72946.1 - 1.1e-08 35.2 0.1 1.6e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY72946.1 - 0.15 11.5 0.2 0.57 9.6 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KEY72947.1 - 4.1e-39 134.5 30.9 4.1e-39 134.5 30.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FGGY_N PF00370.21 KEY72947.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Sugar_tr PF00083.24 KEY72948.1 - 4.7e-77 259.8 24.2 5.7e-77 259.5 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72948.1 - 5e-15 55.3 36.4 5e-15 55.3 36.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY72948.1 - 0.0007 18.6 9.0 0.0007 18.6 9.0 1.7 2 0 0 2 2 2 1 MFS_1 like family IML1 PF12257.8 KEY72948.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 YtpI PF14007.6 KEY72948.1 - 2.9 8.1 11.0 12 6.2 0.5 2.8 2 0 0 2 2 2 0 YtpI-like protein NmrA PF05368.13 KEY72949.1 - 2.9e-16 59.8 0.0 4.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY72949.1 - 3.9e-11 43.2 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY72949.1 - 0.0015 18.0 0.0 0.15 11.5 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PMC2NT PF08066.12 KEY72950.1 - 0.042 14.5 0.0 0.083 13.6 0.0 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF1771 PF08590.10 KEY72950.1 - 1.7 9.0 8.1 2.3 8.7 5.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) ACT_3 PF10000.9 KEY72951.1 - 2e-22 78.8 0.9 2.7e-22 78.5 0.4 1.4 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 KEY72951.1 - 2e-09 37.1 0.0 3.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain P5CR_dimer PF14748.6 KEY72952.1 - 4.8e-35 119.9 1.5 6.1e-35 119.6 0.2 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KEY72952.1 - 9.4e-17 61.4 0.5 2.9e-16 59.8 0.5 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KEY72952.1 - 0.00038 20.5 0.4 0.01 15.8 0.1 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KEY72952.1 - 0.1 12.7 0.1 0.54 10.3 0.0 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ERG4_ERG24 PF01222.17 KEY72953.1 - 1.2e-146 488.8 2.9 1.7e-146 488.4 2.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_11 PF08241.12 KEY72953.1 - 1.4e-21 76.9 0.0 3.8e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY72953.1 - 4.5e-20 72.2 0.0 1.1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY72953.1 - 1e-18 67.6 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY72953.1 - 9e-11 41.9 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY72953.1 - 1.3e-10 41.1 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEY72953.1 - 2.5e-10 40.1 0.0 3.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KEY72953.1 - 2.4e-09 37.8 0.0 5.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KEY72953.1 - 0.0035 15.9 0.0 0.0054 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1295 PF06966.12 KEY72953.1 - 0.0059 16.1 0.6 0.015 14.8 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PrmA PF06325.13 KEY72953.1 - 0.012 15.1 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEY72953.1 - 0.032 13.8 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 KEY72953.1 - 0.047 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KEY72953.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KEY72953.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cyclin_C_2 PF16899.5 KEY72954.1 - 1.5e-30 105.7 0.0 3.7e-28 97.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KEY72954.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAR PF03114.18 KEY72955.1 - 4.6e-45 154.1 1.7 5.6e-45 153.9 1.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KEY72955.1 - 0.00027 20.2 0.5 0.00037 19.7 0.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking AAA_13 PF13166.6 KEY72955.1 - 0.021 13.5 0.2 0.05 12.3 0.1 1.5 1 1 1 2 2 2 0 AAA domain DUF3617 PF12276.8 KEY72955.1 - 0.052 13.9 0.3 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) zf-LITAF-like PF10601.9 KEY72957.1 - 6.3e-06 26.4 1.4 1.1e-05 25.6 1.4 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 KEY72957.1 - 1.3 8.5 3.2 8.6 5.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NACHT PF05729.12 KEY72958.1 - 3e-06 27.2 0.0 7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY72958.1 - 0.01 16.2 1.4 0.044 14.2 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KEY72958.1 - 0.012 15.9 1.3 0.024 14.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KEY72958.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Goodbye PF17109.5 KEY72958.1 - 0.032 14.7 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain AAA_33 PF13671.6 KEY72958.1 - 0.034 14.3 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEY72958.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HET PF06985.11 KEY72959.1 - 3.8e-22 79.2 0.0 8.4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TTSSLRR PF12468.8 KEY72959.1 - 0.067 13.4 0.3 0.83 9.9 0.1 2.5 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein HET PF06985.11 KEY72960.1 - 1.6e-39 135.5 5.1 3.9e-39 134.3 5.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY72960.1 - 7.5e-06 26.4 1.9 2.4e-05 24.9 0.1 2.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Zn_clus PF00172.18 KEY72960.1 - 4.9e-05 23.4 0.3 0.00011 22.2 0.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.30 KEY72960.1 - 0.00092 19.6 0.0 0.14 12.6 0.0 3.1 1 1 1 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KEY72960.1 - 0.0016 19.0 0.2 0.0073 16.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_12 PF13424.6 KEY72960.1 - 0.015 15.6 0.2 0.074 13.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HisG_C PF08029.11 KEY72960.1 - 0.17 12.1 0.0 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain Glyco_hydro_3 PF00933.21 KEY72961.1 - 2.9e-52 178.0 0.0 4.1e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEY72961.1 - 1.6e-07 31.5 0.0 5.2e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain AAA PF00004.29 KEY72962.1 - 8.7e-41 139.4 0.0 1.7e-12 47.9 0.0 5.7 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KEY72962.1 - 2.7e-36 125.1 0.5 1.1e-35 123.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KEY72962.1 - 1.8e-24 87.0 34.1 3.2e-21 76.3 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 KEY72962.1 - 2e-17 63.5 0.2 0.012 15.3 0.0 5.9 5 0 0 5 5 5 4 AAA domain AAA_lid_6 PF17866.1 KEY72962.1 - 9.1e-16 57.8 2.2 2.4e-07 30.8 0.0 3.6 2 0 0 2 2 2 2 AAA lid domain AAA_19 PF13245.6 KEY72962.1 - 2.4e-14 53.9 0.1 0.00014 22.2 0.0 5.4 4 1 0 4 4 4 3 AAA domain Mg_chelatase PF01078.21 KEY72962.1 - 2.6e-09 36.8 0.1 0.34 10.2 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KEY72962.1 - 3.9e-09 36.9 11.1 0.43 10.8 0.1 8.0 5 3 0 6 6 6 2 AAA domain AAA_5 PF07728.14 KEY72962.1 - 6.4e-08 32.7 4.9 0.89 9.6 0.0 5.3 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KEY72962.1 - 1.2e-07 31.8 0.2 0.11 12.2 0.0 5.5 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KEY72962.1 - 6.7e-07 29.2 0.6 1.5 8.5 0.0 4.5 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEY72962.1 - 4e-06 27.2 0.1 5.1 7.5 0.0 5.0 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.6 KEY72962.1 - 4.2e-06 27.2 16.2 0.71 10.2 0.0 6.4 6 1 1 7 7 5 3 AAA ATPase domain IstB_IS21 PF01695.17 KEY72962.1 - 7.1e-06 25.9 0.4 8.4 6.1 0.0 4.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 KEY72962.1 - 2.5e-05 23.9 2.1 3.3 7.2 0.0 6.0 5 1 1 6 6 6 1 AAA domain AAA_24 PF13479.6 KEY72962.1 - 3.9e-05 23.5 11.3 1.6 8.4 0.1 5.4 6 0 0 6 6 5 3 AAA domain Sigma54_activat PF00158.26 KEY72962.1 - 7.3e-05 22.5 1.9 19 4.9 0.0 5.8 5 1 0 5 5 5 0 Sigma-54 interaction domain AAA_7 PF12775.7 KEY72962.1 - 0.00014 21.4 2.1 4.7 6.7 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region ResIII PF04851.15 KEY72962.1 - 0.00047 20.2 6.0 0.018 15.0 0.0 5.2 6 1 1 7 7 5 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KEY72962.1 - 0.00095 19.7 12.1 4.6 7.8 0.0 5.7 5 1 0 5 5 5 1 AAA domain AAA_33 PF13671.6 KEY72962.1 - 0.0026 17.9 14.8 0.32 11.1 0.0 5.2 5 0 0 5 5 4 2 AAA domain TsaE PF02367.17 KEY72962.1 - 0.01 15.8 0.7 14 5.7 0.1 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD_C_2 PF13538.6 KEY72962.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 KEY72962.1 - 0.028 14.2 0.1 1.1 9.0 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase SRP54 PF00448.22 KEY72962.1 - 0.15 11.6 3.9 1.8 8.1 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KEY72962.1 - 0.29 10.3 0.0 0.29 10.3 0.0 6.1 7 0 0 7 7 6 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KEY72962.1 - 0.98 9.3 5.8 33 4.3 0.0 4.2 4 0 0 4 4 4 0 NTPase AAA_17 PF13207.6 KEY72962.1 - 1.7 9.0 15.3 7 7.1 0.1 5.5 5 0 0 5 5 4 0 AAA domain Hydin_ADK PF17213.3 KEY72962.1 - 2.2 8.5 0.0 2.2 8.5 0.0 3.6 3 0 0 3 3 1 0 Hydin Adenylate kinase-like domain CbiA PF01656.23 KEY72962.1 - 4.3 7.4 4.6 1.1e+02 2.8 0.0 4.3 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KEY72962.1 - 9.2 6.8 14.3 68 4.0 0.2 5.7 5 0 0 5 5 5 0 ABC transporter His_Phos_2 PF00328.22 KEY72963.1 - 2.3e-19 70.0 0.0 3.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 KEY72964.1 - 1.9e-16 60.1 0.0 2.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY72964.1 - 1.5e-10 41.0 0.0 3.4e-10 39.9 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY72964.1 - 1.2e-08 35.0 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY72964.1 - 0.029 14.2 0.3 0.061 13.2 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Dak1_2 PF13684.6 KEY72964.1 - 0.063 12.3 0.0 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Ank_2 PF12796.7 KEY72966.1 - 1.3e-15 57.7 0.7 2.4e-15 56.9 0.7 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KEY72966.1 - 2.3e-15 56.2 0.8 0.00085 19.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KEY72966.1 - 2.3e-11 42.9 0.1 0.051 14.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KEY72966.1 - 1.4e-10 41.5 0.0 0.037 14.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY72966.1 - 8.5e-07 29.1 0.5 0.011 16.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Gas_vesicle PF00741.18 KEY72966.1 - 0.012 15.7 2.4 18 5.6 0.1 3.1 3 0 0 3 3 3 0 Gas vesicle protein HEM4 PF02602.15 KEY72966.1 - 0.015 14.6 0.1 5 6.4 0.0 2.5 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD Mic1 PF07035.12 KEY72966.1 - 0.073 12.8 0.0 26 4.5 0.0 2.9 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like Nitro_FeMo-Co PF02579.17 KEY72966.1 - 0.11 12.8 0.1 58 4.1 0.0 2.9 1 1 2 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Glyco_hydro_99 PF16317.5 KEY72966.1 - 0.12 11.5 0.0 12 4.9 0.0 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 99 Skp1_POZ PF03931.15 KEY72968.1 - 1.2e-06 28.5 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Peptidase_M9_N PF08453.10 KEY72968.1 - 0.0079 15.9 0.4 0.014 15.1 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M9 N-terminal AAA_12 PF13087.6 KEY72970.1 - 8.1e-41 139.8 0.0 1.4e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEY72970.1 - 1.1e-23 84.4 0.1 2.8e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY72970.1 - 1.1e-09 38.8 0.1 6.2e-09 36.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain zf_CCCH_4 PF18345.1 KEY72970.1 - 3.4e-05 23.7 8.6 9e-05 22.4 8.6 1.8 1 0 0 1 1 1 1 Zinc finger domain DUF2075 PF09848.9 KEY72970.1 - 4.1e-05 23.0 0.1 0.21 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH_4 PF18044.1 KEY72970.1 - 5.6e-05 22.8 6.2 5.6e-05 22.8 6.2 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEY72970.1 - 7.2e-05 22.6 4.7 7.2e-05 22.6 4.7 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_30 PF13604.6 KEY72970.1 - 0.00034 20.4 0.0 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Torus PF16131.5 KEY72970.1 - 0.0049 17.5 0.2 0.015 16.0 0.2 1.8 1 0 0 1 1 1 1 Torus domain Peptidase_C32 PF05411.12 KEY72970.1 - 0.025 14.5 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase ResIII PF04851.15 KEY72970.1 - 0.031 14.3 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KEY72970.1 - 0.062 13.0 0.6 6.4 6.4 0.0 3.6 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase SDH_sah PF01972.16 KEY72970.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DZR PF12773.7 KEY72970.1 - 0.64 10.1 10.8 9.1 6.4 4.2 3.2 2 1 0 2 2 2 0 Double zinc ribbon DUF1115 PF06544.12 KEY72971.1 - 3.7e-13 49.8 0.0 5.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF5315 PF17242.2 KEY72971.1 - 0.075 12.9 0.2 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) RTA1 PF04479.13 KEY72972.1 - 1.4e-58 197.9 13.5 2.1e-58 197.4 13.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Glycophorin_A PF01102.18 KEY72972.1 - 0.029 14.6 0.3 0.056 13.7 0.3 1.5 1 0 0 1 1 1 0 Glycophorin A ABC2_membrane PF01061.24 KEY72973.1 - 1.5e-82 276.1 59.7 3.6e-43 147.4 27.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEY72973.1 - 2.6e-34 118.7 0.0 4.1e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY72973.1 - 6.2e-28 96.6 4.6 8e-25 86.6 0.1 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY72973.1 - 8.2e-15 55.2 1.4 8.2e-15 55.2 1.4 2.7 3 1 0 3 3 2 1 ABC-transporter N-terminal AAA_21 PF13304.6 KEY72973.1 - 6.7e-06 26.1 0.5 0.0072 16.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEY72973.1 - 4.1e-05 23.5 0.0 0.00041 20.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KEY72973.1 - 5.4e-05 23.8 0.0 0.0049 17.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY72973.1 - 6.7e-05 23.1 0.1 0.0087 16.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEY72973.1 - 9.2e-05 22.9 2.6 0.0038 17.6 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KEY72973.1 - 9.6e-05 22.0 0.1 0.36 10.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEY72973.1 - 0.00028 21.0 0.4 0.083 13.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KEY72973.1 - 0.0004 20.7 0.0 0.24 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KEY72973.1 - 0.00049 19.7 0.1 0.0048 16.5 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KEY72973.1 - 0.003 17.1 0.0 0.42 10.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEY72973.1 - 0.0035 17.6 1.6 0.0071 16.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 KEY72973.1 - 0.0064 15.9 1.6 0.052 13.0 0.0 2.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KEY72973.1 - 0.016 14.9 0.0 0.31 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KEY72973.1 - 0.02 14.6 1.0 1.8 8.2 0.0 3.0 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KEY72973.1 - 0.029 14.3 0.2 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 KEY72973.1 - 0.034 14.0 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.18 KEY72973.1 - 0.053 12.9 0.4 7.9 5.7 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KEY72973.1 - 0.092 11.9 0.1 3.1 6.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 KEY72973.1 - 0.11 11.8 0.1 0.54 9.5 0.1 1.9 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 KEY72973.1 - 0.14 11.9 0.2 1.2 8.9 0.3 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 KEY72974.1 - 7.9e-56 186.6 20.9 1.9e-15 57.2 0.2 6.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY72974.1 - 2.4e-39 133.2 10.5 5.4e-08 33.2 0.1 7.5 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY72974.1 - 9.7e-30 99.3 6.4 0.00017 21.7 0.0 11.2 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 KEY72974.1 - 5.7e-28 96.1 23.9 4.6e-06 26.8 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KEY72974.1 - 9e-28 96.0 4.1 5.1e-06 26.7 0.1 9.4 2 2 7 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.12 KEY72974.1 - 1.1e-11 44.9 0.1 2.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KEY72974.1 - 3e-11 43.0 0.5 1.2e-10 41.1 0.4 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KEY72974.1 - 2.1e-05 25.0 0.2 0.00013 22.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY72974.1 - 0.00082 19.7 0.0 0.003 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEY72974.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEY72974.1 - 0.016 14.4 0.2 0.072 12.3 0.1 2.0 1 1 0 1 1 1 0 NB-ARC domain MukB PF04310.12 KEY72975.1 - 0.061 13.1 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 MukB N-terminal NACHT PF05729.12 KEY72976.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SNF2_N PF00176.23 KEY72977.1 - 2.5e-45 154.7 0.0 2.3e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain p450 PF00067.22 KEY72978.1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RHIM PF12721.7 KEY72979.1 - 0.047 14.2 11.0 5.2 7.6 0.7 3.6 3 1 1 4 4 4 0 RIP homotypic interaction motif Peptidase_S10 PF00450.22 KEY72980.1 - 3.6e-61 207.8 0.0 4.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_glycop PF01528.16 KEY72980.1 - 0.53 9.1 1.7 0.38 9.6 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Tetraspanin PF00335.20 KEY72983.1 - 8.2e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Tetraspanin family Alpha_GJ PF03229.13 KEY72984.1 - 4.9 7.7 12.6 3.6 8.2 9.8 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J Pkinase PF00069.25 KEY72987.1 - 3.8e-09 36.3 0.0 7.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY72987.1 - 0.0045 16.3 0.0 0.0089 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KEY72987.1 - 0.0051 16.4 0.7 0.012 15.2 0.1 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KEY72987.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DMRT-like PF15791.5 KEY72987.1 - 0.15 12.5 0.1 0.25 11.8 0.1 1.2 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 NTP_transf_6 PF06042.11 KEY72988.1 - 8.2e-53 178.5 0.0 9.4e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase MFS_1 PF07690.16 KEY72989.1 - 8e-16 57.9 53.8 5.2e-12 45.3 38.2 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY72989.1 - 0.017 13.6 17.6 0.022 13.2 11.7 2.6 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) SapB_1 PF05184.15 KEY72990.1 - 0.033 14.2 0.2 0.033 14.2 0.2 1.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 ssDNA-exonuc_C PF10141.9 KEY72991.1 - 0.037 13.7 0.5 0.078 12.6 0.5 1.4 1 1 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain FMN_dh PF01070.18 KEY72992.1 - 1e-84 284.5 0.1 1.5e-47 162.3 0.0 3.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEY72992.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEY72992.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KEY72992.1 - 0.013 15.0 0.0 8.9 5.7 0.0 3.0 3 0 0 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.21 KEY72992.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PA PF02225.22 KEY72992.1 - 0.22 11.6 0.8 0.54 10.3 0.8 1.6 1 1 0 1 1 1 0 PA domain NmrA PF05368.13 KEY72995.1 - 2e-64 217.3 0.1 2.4e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY72995.1 - 2.7e-17 63.3 1.3 3.8e-17 62.8 1.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY72995.1 - 0.0029 17.1 0.1 0.0057 16.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY72995.1 - 0.058 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CIAPIN1 PF05093.13 KEY72996.1 - 6e-43 145.4 3.4 1e-42 144.7 3.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KEY72996.1 - 6.8e-34 116.9 0.0 9.7e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Fasciclin PF02469.22 KEY72997.1 - 9.9e-43 145.4 0.2 7.8e-26 90.8 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Sugar_tr PF00083.24 KEY72999.1 - 2.4e-72 244.2 15.8 3e-72 243.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY72999.1 - 1.1e-27 96.9 17.7 1.7e-27 96.3 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY72999.1 - 2.9e-07 29.3 0.3 4.8e-07 28.6 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEY72999.1 - 0.0019 16.5 0.2 0.0019 16.5 0.2 2.2 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_18 PF00704.28 KEY73000.1 - 1.1e-06 28.6 0.3 1.3e-06 28.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1269 PF06897.12 KEY73000.1 - 0.15 12.3 1.6 0.42 10.9 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) APH PF01636.23 KEY73001.1 - 5.3e-15 56.0 0.0 1.2e-14 54.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KEY73001.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 KEY73001.1 - 0.14 11.7 0.1 0.59 9.7 0.1 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase GRDP-like PF07173.12 KEY73003.1 - 5.1e-19 69.3 1.3 9.4e-16 58.7 0.0 2.9 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like Lipase_3 PF01764.25 KEY73003.1 - 1.6e-15 57.2 0.0 3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEY73003.1 - 0.063 13.9 0.2 0.063 13.9 0.2 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family YL1 PF05764.13 KEY73005.1 - 4.1 7.4 15.1 6 6.9 15.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cellulase PF00150.18 KEY73006.1 - 2.7e-16 59.8 2.3 3.5e-16 59.4 2.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF45 PF01863.17 KEY73006.1 - 0.13 12.3 0.2 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 GlnD_UR_UTase PF08335.11 KEY73006.1 - 0.21 11.7 0.1 0.54 10.4 0.1 1.6 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase GFO_IDH_MocA PF01408.22 KEY73007.1 - 6e-12 46.5 0.0 1e-11 45.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEY73007.1 - 3.5e-05 24.4 0.1 0.00013 22.6 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KEY73007.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Bac_rhodopsin PF01036.18 KEY73008.1 - 3.2e-50 170.8 13.4 5.6e-50 170.0 13.4 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GFO_IDH_MocA_C PF02894.17 KEY73008.1 - 7.1e-17 61.5 0.1 1.8e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KEY73008.1 - 1.5e-14 54.9 0.0 5.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Heliorhodopsin PF18761.1 KEY73008.1 - 0.00011 21.6 2.5 0.00018 20.9 2.3 1.4 1 1 0 1 1 1 1 Heliorhodopsin DUF2754 PF10953.8 KEY73008.1 - 0.21 11.9 3.1 0.58 10.4 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF1772 PF08592.11 KEY73008.1 - 0.44 10.9 7.3 3.9 7.8 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KEY73009.1 - 1.8e-32 112.7 30.9 2.4e-32 112.3 30.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhK PF14145.6 KEY73009.1 - 1.3 8.9 11.0 5.8 6.9 3.5 3.7 3 1 0 3 3 3 0 YrhK-like protein COA2 PF17051.5 KEY73011.1 - 0.13 12.4 0.8 0.25 11.4 0.3 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 NmrA PF05368.13 KEY73012.1 - 5.2e-16 58.9 0.0 7.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY73012.1 - 1.1e-14 54.7 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY73012.1 - 0.0007 19.1 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KEY73012.1 - 0.0044 17.4 0.2 0.015 15.7 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 KEY73012.1 - 0.0079 15.8 0.2 0.016 14.8 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 KEY73012.1 - 0.014 15.5 0.1 0.037 14.2 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KEY73012.1 - 0.02 15.5 0.4 0.062 13.9 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KEY73012.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ntox47 PF15540.6 KEY73012.1 - 0.027 14.8 0.1 0.055 13.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial toxin 47 KR PF08659.10 KEY73012.1 - 0.035 14.0 0.6 0.069 13.1 0.1 1.7 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.23 KEY73012.1 - 0.076 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Orexin_rec2 PF03827.13 KEY73012.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Orexin receptor type 2 Shikimate_DH PF01488.20 KEY73012.1 - 0.19 11.8 0.1 0.42 10.7 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3336 PF11815.8 KEY73013.1 - 1.3e-36 125.4 1.2 2.4e-36 124.5 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEY73013.1 - 5.2e-21 75.8 0.0 1.2e-20 74.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase AhpC-TSA PF00578.21 KEY73014.1 - 3.8e-29 101.1 0.0 5e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KEY73014.1 - 6e-13 48.4 0.1 1.1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KEY73014.1 - 3.7e-12 46.2 0.0 5.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_4 PF13418.6 KEY73015.1 - 1.1e-17 63.7 0.2 2.7e-07 30.5 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY73015.1 - 3.1e-16 59.2 9.6 5.7e-09 36.1 0.0 6.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY73015.1 - 7.2e-15 54.7 6.3 5.5e-05 23.3 1.4 4.9 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KEY73015.1 - 4.8e-13 48.5 0.2 0.00027 20.4 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KEY73015.1 - 2.5e-12 46.5 6.4 5.3e-06 26.3 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KEY73015.1 - 2.6e-12 46.2 1.1 4.7e-05 23.2 0.0 5.1 5 1 0 5 5 5 3 Kelch motif BTB PF00651.31 KEY73015.1 - 0.022 15.0 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.28 KEY73016.1 - 2.2e-70 237.4 0.0 3e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY73016.1 - 4.1e-10 40.5 0.0 1.1e-09 39.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WW PF00397.26 KEY73016.1 - 0.085 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 WW domain PIG-S PF10510.9 KEY73017.1 - 3.2e-166 554.1 0.3 3.7e-166 553.9 0.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Hydrolase_4 PF12146.8 KEY73018.1 - 1.2e-05 24.7 0.0 0.00076 18.8 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KEY73018.1 - 0.00011 21.8 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KEY73018.1 - 0.0046 16.6 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Myb_DNA-binding PF00249.31 KEY73019.1 - 6.1e-06 26.3 0.1 1.5e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY73019.1 - 0.0063 16.8 0.1 0.019 15.2 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 KEY73019.1 - 0.058 13.5 1.0 0.12 12.5 1.0 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CelD_N PF02927.14 KEY73019.1 - 0.12 13.3 0.0 0.42 11.5 0.0 1.9 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain SelP_N PF04592.14 KEY73019.1 - 6.9 6.0 12.4 6.7 6.0 11.0 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region UbiA PF01040.18 KEY73020.1 - 5.2e-58 196.3 14.2 5.2e-58 196.3 14.2 2.0 1 1 1 2 2 2 1 UbiA prenyltransferase family TAL_FSA PF00923.19 KEY73021.1 - 5.6e-43 147.3 0.0 7.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SAICAR_synt PF01259.18 KEY73022.1 - 1.2e-97 326.5 0.0 1.4e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase 4HBT_3 PF13622.6 KEY73022.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily RGI_lyase PF18370.1 KEY73024.1 - 1.8e-20 73.0 0.1 6.7e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Rhamnogalacturonan I lyases beta-sheet domain PQQ_2 PF13360.6 KEY73024.1 - 0.0015 18.2 0.1 0.05 13.2 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain VCBS PF13517.6 KEY73024.1 - 0.0017 18.9 4.3 0.0017 18.9 4.3 5.5 6 2 0 6 6 6 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 KEY73024.1 - 0.022 14.7 0.2 0.52 10.3 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat PepSY_2 PF13670.6 KEY73024.1 - 0.3 11.1 3.2 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain FG-GAP PF01839.23 KEY73024.1 - 2.6 8.3 23.5 0.19 11.9 2.1 4.7 5 0 0 5 5 5 0 FG-GAP repeat Fungal_trans PF04082.18 KEY73025.1 - 4.4e-18 65.3 0.0 8.3e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73025.1 - 1.9e-06 27.9 16.7 3.3e-06 27.1 16.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 KEY73026.1 - 1.1e-05 24.8 1.1 2.2e-05 23.7 1.1 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KEY73027.1 - 3.3e-15 55.9 32.2 3.3e-15 55.9 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 KEY73028.1 - 2e-128 428.4 0.2 2.6e-128 428.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans_2 PF11951.8 KEY73029.1 - 8.6e-43 146.6 4.6 1.1e-42 146.3 4.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73029.1 - 1.6e-09 37.7 11.1 3.3e-09 36.7 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_AbiU2 PF18734.1 KEY73029.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AbiU2 Arginase PF00491.21 KEY73030.1 - 2e-90 303.1 0.0 2.6e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KEY73030.1 - 0.061 13.6 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 KEY73031.1 - 6e-54 182.0 23.2 1.6e-27 96.2 8.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KEY73031.1 - 4.5e-10 39.8 4.0 4.5e-10 39.8 4.0 4.1 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain AA_permease_2 PF13520.6 KEY73032.1 - 5.7e-49 167.1 46.4 7.3e-49 166.7 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY73032.1 - 1.5e-21 76.6 40.4 2.2e-21 76.0 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease COX7B PF05392.11 KEY73032.1 - 0.057 13.1 0.4 3.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Fungal_trans_2 PF11951.8 KEY73033.1 - 1.1e-48 165.9 5.1 1.6e-48 165.5 5.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73033.1 - 2.7e-06 27.4 11.2 5.2e-06 26.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KEY73034.1 - 1.9e-21 77.3 0.0 2.9e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mac PF12464.8 KEY73035.1 - 3.8e-16 59.1 0.1 6.1e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KEY73035.1 - 1.2e-12 47.1 8.4 5e-10 38.7 4.8 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEY73035.1 - 1.4e-09 37.5 14.1 7e-09 35.3 5.0 2.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Pro_Al_protease PF02983.14 KEY73038.1 - 2.1e-12 46.9 0.6 2.1e-12 46.9 0.6 2.1 3 0 0 3 3 3 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KEY73038.1 - 5.6e-08 32.9 10.9 1.3e-07 31.7 10.9 1.5 1 1 0 1 1 1 1 Trypsin PAP2 PF01569.21 KEY73040.1 - 1.3e-26 92.9 1.7 1.3e-26 92.9 1.7 2.0 2 1 1 3 3 3 1 PAP2 superfamily BPD_transp_2 PF02653.16 KEY73040.1 - 0.07 12.3 10.9 0.036 13.2 2.8 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF983 PF06170.12 KEY73040.1 - 1.3 9.4 8.1 3.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TPPK_C PF12555.8 KEY73040.1 - 2.1 8.5 7.2 1.3 9.2 2.8 2.6 1 1 1 2 2 2 0 Thiamine pyrophosphokinase C terminal PAP2_C PF14360.6 KEY73040.1 - 8.6 7.0 8.3 0.86 10.2 2.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily C-terminal FG-GAP_2 PF14312.6 KEY73041.1 - 5.5 7.3 14.4 23 5.4 4.1 4.0 4 1 0 4 4 4 0 FG-GAP repeat Tyrosinase PF00264.20 KEY73042.1 - 2.8e-44 152.0 0.0 3.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FMO-like PF00743.19 KEY73043.1 - 3e-16 58.9 0.1 1.8e-15 56.4 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEY73043.1 - 2.1e-12 47.1 0.0 5.2e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEY73043.1 - 3.3e-10 39.6 0.0 1.5e-06 27.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEY73043.1 - 1.9e-08 34.0 0.0 4e-07 29.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY73043.1 - 5.6e-08 32.4 0.0 5.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY73043.1 - 0.0001 22.3 0.0 0.0022 18.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KEY73043.1 - 0.00018 21.2 0.0 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEY73043.1 - 0.0043 16.3 0.0 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KEY73043.1 - 0.035 14.7 0.0 18 6.0 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY73043.1 - 0.05 12.3 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein GARS_N PF02844.15 KEY73043.1 - 0.058 14.2 0.0 0.26 12.1 0.0 2.2 3 0 0 3 3 2 0 Phosphoribosylglycinamide synthetase, N domain Shikimate_DH PF01488.20 KEY73043.1 - 0.2 11.7 0.0 1.8 8.6 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HET PF06985.11 KEY73044.1 - 3.4e-22 79.4 0.0 1.5e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEY73045.1 - 9.2e-32 109.5 0.4 1.1e-15 58.0 0.0 3.5 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73045.1 - 1.2e-27 95.9 0.7 7.8e-10 39.1 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73045.1 - 1.6e-27 92.5 0.2 1.5e-05 25.0 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KEY73045.1 - 9.5e-26 89.1 3.5 9.9e-06 25.8 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KEY73045.1 - 2e-19 69.4 1.2 5.9e-08 32.8 0.2 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 KEY73045.1 - 9.9e-11 41.8 0.2 3.1e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEY73045.1 - 3.4e-07 30.8 0.0 8.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KEY73045.1 - 0.0028 16.9 1.5 0.55 9.4 0.1 2.2 1 1 1 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.22 KEY73045.1 - 0.005 16.1 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEY73045.1 - 0.0065 16.7 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.7 KEY73045.1 - 0.011 16.3 1.2 0.026 15.2 0.0 2.2 3 0 0 3 3 2 0 Alpha/beta hydrolase family AAA_7 PF12775.7 KEY73045.1 - 0.034 13.7 0.2 0.074 12.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEY73045.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KEY73045.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PGAP1 PF07819.13 KEY73045.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_10 PF12846.7 KEY73045.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AMP-binding PF00501.28 KEY73046.1 - 1.6e-148 494.8 0.0 1.1e-74 251.5 0.0 2.6 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.20 KEY73046.1 - 1.8e-131 439.0 0.0 3e-37 128.4 0.0 5.8 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KEY73046.1 - 3.3e-22 78.6 0.1 2.4e-10 40.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEY73046.1 - 1.6e-05 25.8 0.2 0.002 19.1 0.1 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Beta_elim_lyase PF01212.21 KEY73047.1 - 5e-58 196.7 0.0 6.2e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KEY73047.1 - 2.7e-06 26.8 0.0 3.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEY73047.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEY73047.1 - 0.011 14.3 0.0 0.021 13.3 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEY73047.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Trp_DMAT PF11991.8 KEY73048.1 - 6.9e-70 236.3 0.0 1e-69 235.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KEY73049.1 - 3.6e-47 161.2 0.0 6.7e-34 117.4 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KEY73050.1 - 1.3e-66 225.3 0.0 1.6e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KEY73051.1 - 3.3e-64 216.9 0.0 8.7e-64 215.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY73051.1 - 1.7e-50 171.4 0.0 6.1e-50 169.6 0.0 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KEY73051.1 - 1.8e-44 152.5 1.0 3.1e-44 151.8 1.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEY73051.1 - 2.1e-44 152.0 0.1 3.4e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY73051.1 - 3.6e-31 107.6 0.6 9.6e-31 106.3 0.2 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEY73051.1 - 1.2e-21 77.3 0.0 5.9e-21 75.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KEY73051.1 - 2.9e-14 53.0 0.0 1.5e-12 47.4 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KEY73051.1 - 2.4e-12 46.9 0.0 8.2e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KEY73051.1 - 3.2e-12 46.9 0.1 2.1e-11 44.3 0.1 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEY73051.1 - 9.7e-12 45.1 0.1 3e-11 43.5 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KEY73051.1 - 2.5e-11 44.8 0.0 1.4e-10 42.4 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KEY73051.1 - 2.1e-10 40.7 0.0 4.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73051.1 - 1e-09 39.0 0.0 6.2e-09 36.4 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.12 KEY73051.1 - 2.1e-07 30.8 0.1 5.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 KEY73051.1 - 1e-05 26.1 0.0 6.2e-05 23.6 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73051.1 - 3.5e-05 23.6 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KEY73051.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SAT PF16073.5 KEY73051.1 - 0.0054 16.5 0.5 0.029 14.1 0.5 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KEY73051.1 - 0.044 13.1 0.2 0.32 10.3 0.2 2.1 2 0 0 2 2 2 0 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KEY73051.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY73051.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_33 PF10017.9 KEY73051.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PALP PF00291.25 KEY73051.1 - 5 6.4 7.7 2.8 7.3 0.1 2.9 4 0 0 4 4 3 0 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 KEY73053.1 - 2e-24 86.4 0.0 8.7e-24 84.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73053.1 - 1.1e-14 54.4 0.0 8.4e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ApoLp-III PF07464.11 KEY73053.1 - 0.14 12.3 1.4 0.25 11.4 1.4 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AA_permease PF00324.21 KEY73055.1 - 2.9e-25 88.8 35.4 6.2e-20 71.2 18.7 3.1 3 0 0 3 3 3 2 Amino acid permease AA_permease_2 PF13520.6 KEY73055.1 - 2.1e-09 36.8 18.9 2.1e-09 36.8 18.9 3.0 3 0 0 3 3 3 2 Amino acid permease Alpha-L-AF_C PF06964.12 KEY73056.1 - 7.7e-29 101.0 0.6 1.2e-28 100.4 0.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_30C PF17189.4 KEY73056.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_10 PF00331.20 KEY73057.1 - 1.2e-104 349.9 0.1 1.4e-104 349.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KEY73057.1 - 1.9e-13 50.1 13.3 1.9e-13 50.1 13.3 2.1 3 0 0 3 3 3 1 Fungal cellulose binding domain CBM_1 PF00734.18 KEY73058.1 - 2.1e-13 49.9 17.8 8.4e-13 48.0 17.8 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KEY73058.1 - 7.6e-06 25.5 0.5 5.7e-05 22.7 0.2 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KEY73058.1 - 1.3e-05 24.8 1.2 4.6e-05 23.0 0.7 2.0 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 KEY73058.1 - 0.002 17.8 0.7 0.018 14.7 0.7 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KEY73058.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KEY73058.1 - 0.17 10.5 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Toxin_7 PF05980.12 KEY73058.1 - 1.7 8.9 8.1 3.7 7.9 8.1 1.6 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_3_C PF01915.22 KEY73059.1 - 1.2e-34 120.1 0.0 1.8e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY73059.1 - 3.6e-30 105.4 0.0 6.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY73059.1 - 2.7e-05 24.2 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Polysacc_deac_1 PF01522.21 KEY73060.1 - 2.6e-15 56.4 0.0 6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KEY73060.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) ThuA PF06283.11 KEY73060.1 - 0.097 12.9 0.0 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 Trehalose utilisation PhoD PF09423.10 KEY73061.1 - 7.2e-115 383.7 4.3 8.9e-115 383.4 4.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KEY73061.1 - 9e-25 87.0 0.3 1e-16 61.2 0.1 2.7 2 0 0 2 2 2 2 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KEY73061.1 - 0.087 13.4 0.1 0.23 12.1 0.1 1.8 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KEY73061.1 - 0.1 13.1 2.9 0.14 12.7 0.5 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Glug PF07581.12 KEY73061.1 - 0.2 12.1 0.7 6.4 7.4 0.1 2.9 2 0 0 2 2 2 0 The GLUG motif MFS_1 PF07690.16 KEY73062.1 - 4.3e-32 111.4 17.6 3.1e-31 108.6 16.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73062.1 - 3.2e-07 29.6 1.9 3.2e-07 29.6 1.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter CPP1-like PF11833.8 KEY73062.1 - 3.3 7.3 7.2 4.8 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_trans PF04082.18 KEY73063.1 - 1.2e-13 50.8 0.1 1.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Isochorismatase PF00857.20 KEY73064.1 - 2.6e-27 96.1 0.0 3.3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.13 KEY73065.1 - 4e-56 190.2 0.1 5.3e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY73065.1 - 1.1e-11 44.3 0.2 3.5e-11 42.7 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY73065.1 - 0.00055 19.5 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KEY73065.1 - 0.054 12.3 0.0 0.17 10.7 0.0 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase p450 PF00067.22 KEY73066.1 - 5.9e-58 196.7 0.0 8.5e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 KEY73067.1 - 1.4e-148 495.2 0.0 1.7e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.15 KEY73068.1 - 1.5e-29 103.1 32.4 1.7e-28 99.6 32.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 KEY73068.1 - 0.032 14.0 17.7 0.54 10.0 17.2 2.6 1 1 0 1 1 1 0 Cation efflux family Peptidase_M43 PF05572.13 KEY73069.1 - 3.6e-07 30.2 0.1 5.9e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KEY73069.1 - 6.1e-05 23.3 0.3 9.5e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KEY73069.1 - 0.0027 17.6 0.1 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KEY73069.1 - 0.0041 16.1 0.8 0.0081 15.1 0.5 1.6 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M10 PF00413.24 KEY73069.1 - 0.006 16.4 0.1 0.0082 16.0 0.1 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 KEY73069.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KEY73069.1 - 0.022 14.0 0.2 0.042 13.1 0.2 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 KEY73069.1 - 0.039 14.5 1.2 0.063 13.8 1.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KEY73069.1 - 0.048 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_S8 PF00082.22 KEY73070.1 - 1e-13 51.2 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KEY73070.1 - 2.2e-05 24.9 0.0 0.0026 18.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73070.1 - 0.00031 21.2 0.0 8.5 7.1 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY73070.1 - 0.022 15.1 0.0 8.6 6.8 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73070.1 - 0.039 14.5 0.0 17 6.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KEY73072.1 - 6.2e-80 263.9 2.4 6.9e-12 45.8 0.4 12.7 4 3 7 12 12 12 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73072.1 - 2e-58 194.0 26.3 2.3e-06 28.0 0.1 17.6 13 4 7 20 20 20 14 Ankyrin repeats (many copies) Ank PF00023.30 KEY73072.1 - 1.8e-37 126.2 26.2 0.0019 18.5 0.0 17.8 18 0 0 18 18 18 8 Ankyrin repeat Ank_3 PF13606.6 KEY73072.1 - 6.2e-36 118.3 17.5 0.055 14.0 0.0 21.5 24 0 0 24 24 22 5 Ankyrin repeat Ank_5 PF13857.6 KEY73072.1 - 5.6e-32 109.4 25.5 1.2e-07 31.9 0.2 14.6 13 3 3 16 16 16 6 Ankyrin repeats (many copies) SPRY PF00622.28 KEY73072.1 - 5e-10 39.5 0.0 9.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain AAA_16 PF13191.6 KEY73072.1 - 0.0002 21.8 0.1 0.0002 21.8 0.1 3.3 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.12 KEY73072.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEY73072.1 - 0.001 19.3 0.1 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KEY73072.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KEY73072.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEY73072.1 - 0.19 11.7 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain MFS_1 PF07690.16 KEY73074.1 - 9e-40 136.7 43.9 1.5e-37 129.4 33.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_61 PF03443.14 KEY73075.1 - 1.1e-44 152.9 0.0 1.4e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY73075.1 - 8.5e-12 44.8 15.4 2.6e-11 43.3 15.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEY73075.1 - 0.57 10.5 10.0 2.7 8.3 10.0 2.1 1 1 0 1 1 1 0 Toxin 7 Frag1 PF10277.9 KEY73077.1 - 2.6e-43 148.1 13.9 3e-43 147.9 13.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 KEY73077.1 - 0.018 13.7 6.4 0.026 13.2 6.4 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 DUF998 PF06197.13 KEY73077.1 - 0.038 13.6 12.7 0.052 13.1 11.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF998) ATP-synt_C PF00137.21 KEY73077.1 - 0.084 13.2 0.4 0.084 13.2 0.4 2.9 4 0 0 4 4 4 0 ATP synthase subunit C CBM_2 PF00553.19 KEY73077.1 - 0.099 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Cellulose binding domain 7TM_GPCR_Srh PF10318.9 KEY73077.1 - 0.46 9.5 7.5 0.79 8.7 7.5 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Bax1-I PF01027.20 KEY73077.1 - 6 6.6 20.1 0.83 9.4 8.0 2.9 1 1 2 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 NmrA PF05368.13 KEY73078.1 - 4.2e-32 111.6 0.0 5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY73078.1 - 1.7e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY73078.1 - 2.3e-06 27.2 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY73078.1 - 0.00022 21.5 0.1 0.00096 19.4 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY73078.1 - 0.00055 20.4 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KEY73078.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KEY73078.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KEY73078.1 - 0.013 16.1 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KEY73078.1 - 0.058 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KEY73078.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KEY73078.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KEY73078.1 - 0.18 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KEY73078.1 - 0.2 11.0 0.4 0.49 9.7 0.3 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 KEY73082.1 - 0.0016 18.1 0.0 0.0018 17.9 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain COesterase PF00135.28 KEY73083.1 - 1.5e-69 235.3 0.0 3.7e-69 233.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY73083.1 - 8.8e-14 51.9 0.2 2.4e-13 50.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY73083.1 - 0.0039 16.7 0.3 0.0082 15.6 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DDE_Tnp_1_7 PF13843.6 KEY73084.1 - 5.4e-06 26.0 0.0 7.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 RSN1_TM PF13967.6 KEY73085.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Aminotran_5 PF00266.19 KEY73086.1 - 6e-40 137.3 0.0 8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Git3 PF11710.8 KEY73088.1 - 1.7e-18 67.2 4.6 4.9e-18 65.7 4.6 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KEY73088.1 - 1.2e-05 25.3 0.0 4.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KEY73088.1 - 0.00063 19.0 4.2 0.0089 15.2 2.1 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Ribonuc_L-PSP PF01042.21 KEY73089.1 - 4.6e-13 49.2 0.0 5.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CN_hydrolase PF00795.22 KEY73090.1 - 7.5e-38 130.4 0.0 9e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 KEY73090.1 - 0.06 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of band_7 Esterase_phd PF10503.9 KEY73091.1 - 2e-23 83.1 0.6 3.1e-23 82.4 0.6 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEY73091.1 - 1.1e-14 54.5 0.5 1.6e-14 53.9 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KEY73091.1 - 1.5e-10 40.8 11.0 1.5e-10 40.8 11.0 2.6 3 0 0 3 3 2 1 Fungal cellulose binding domain Esterase PF00756.20 KEY73091.1 - 0.00021 21.0 0.2 0.00033 20.4 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KEY73091.1 - 0.00047 19.9 0.8 0.0047 16.6 0.3 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY73091.1 - 0.0014 17.9 0.2 0.11 11.7 0.2 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEY73091.1 - 0.0016 18.4 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KEY73091.1 - 0.0029 16.5 0.1 0.0044 15.9 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 BAAT_C PF08840.11 KEY73091.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KEY73091.1 - 0.039 12.8 0.5 0.071 12.0 0.5 1.3 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.18 KEY73091.1 - 0.053 13.1 0.4 0.15 11.6 0.4 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 KEY73091.1 - 0.069 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KEY73091.1 - 0.096 13.3 1.3 0.16 12.5 1.3 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 KEY73091.1 - 0.24 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Toxin_7 PF05980.12 KEY73091.1 - 0.55 10.5 6.5 0.19 12.0 3.1 2.0 2 0 0 2 2 2 0 Toxin 7 HET PF06985.11 KEY73092.1 - 5.1e-11 43.1 3.3 1.2e-08 35.4 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Amidohydro_1 PF01979.20 KEY73093.1 - 3.4e-57 194.3 0.0 4e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY73093.1 - 2.2e-14 53.8 1.4 9.1e-10 38.6 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family OTT_1508_deam PF14441.6 KEY73094.1 - 1.4e-18 66.6 0.2 3.5e-18 65.4 0.2 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DLH PF01738.18 KEY73096.1 - 1.7e-17 63.7 0.0 3.4e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans_2 PF11951.8 KEY73097.1 - 0.024 13.5 0.5 0.91 8.3 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ribonuclease_T2 PF00445.18 KEY73098.1 - 1.2e-39 136.4 0.1 1.9e-39 135.8 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family HMMR_N PF15905.5 KEY73099.1 - 0.00045 19.8 9.0 0.00074 19.1 9.0 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KEY73099.1 - 0.0086 15.0 16.4 0.1 11.4 4.3 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF4407 PF14362.6 KEY73099.1 - 0.015 14.6 7.8 0.03 13.7 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCC-bdg_PDZ PF10506.9 KEY73099.1 - 0.016 15.2 6.7 8 6.6 0.4 3.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Baculo_PEP_C PF04513.12 KEY73099.1 - 0.017 15.1 6.7 0.093 12.8 1.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KEY73099.1 - 0.019 15.2 5.3 0.019 15.2 5.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3053 PF11254.8 KEY73099.1 - 0.025 14.2 4.1 0.024 14.3 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) UPF0242 PF06785.11 KEY73099.1 - 0.034 14.2 7.1 0.29 11.2 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KEY73099.1 - 0.038 14.3 9.3 2 8.7 3.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 KEY73099.1 - 0.048 13.9 13.0 0.38 11.0 3.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc29 PF17082.5 KEY73099.1 - 0.051 13.4 8.1 0.025 14.5 4.6 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 TPR_MLP1_2 PF07926.12 KEY73099.1 - 0.061 13.4 18.4 0.41 10.7 5.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 KEY73099.1 - 0.075 12.6 5.3 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Prefoldin_2 PF01920.20 KEY73099.1 - 0.082 12.9 8.0 0.13 12.2 0.1 3.2 2 1 1 3 3 3 0 Prefoldin subunit Filament PF00038.21 KEY73099.1 - 0.11 12.1 9.5 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein Cnn_1N PF07989.11 KEY73099.1 - 0.21 11.8 10.6 0.23 11.7 4.1 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 GBR2_CC PF18455.1 KEY73099.1 - 0.21 11.7 2.4 0.88 9.7 2.3 2.1 1 1 1 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain PRKG1_interact PF15898.5 KEY73099.1 - 0.22 12.4 13.3 1 10.3 1.9 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2959 PF11172.8 KEY73099.1 - 0.47 10.6 7.5 5.1 7.2 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) EMP24_GP25L PF01105.24 KEY73099.1 - 0.52 10.2 4.3 0.91 9.4 0.3 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RmuC PF02646.16 KEY73099.1 - 0.59 9.2 10.3 0.2 10.7 3.7 2.2 2 0 0 2 2 2 0 RmuC family COG5 PF10392.9 KEY73099.1 - 0.66 10.2 8.0 2.2 8.4 7.0 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Jnk-SapK_ap_N PF09744.9 KEY73099.1 - 0.89 9.8 11.7 1.7 8.9 2.8 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 APG17 PF04108.12 KEY73099.1 - 0.98 8.5 10.4 1.8 7.6 10.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 Occludin_ELL PF07303.13 KEY73099.1 - 1 10.1 7.3 1.1 10.1 1.5 2.8 2 1 1 3 3 3 0 Occludin homology domain YabA PF06156.13 KEY73099.1 - 1 10.0 12.2 2.3 8.9 2.1 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 KEY73099.1 - 1.2 9.3 11.8 2.2 8.5 1.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 KEY73099.1 - 1.3 9.1 7.7 7.7 6.6 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RPW8 PF05659.11 KEY73099.1 - 1.3 8.7 4.8 35 4.1 0.0 3.3 2 2 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Uso1_p115_C PF04871.13 KEY73099.1 - 1.7 9.0 12.7 7.6 6.9 3.6 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 KEY73099.1 - 1.8 8.4 8.7 0.84 9.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2730 PF10805.8 KEY73099.1 - 1.8 8.7 4.9 11 6.1 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) Phage_GPO PF05929.11 KEY73099.1 - 1.8 8.1 11.6 2.7 7.5 3.0 2.1 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase KLRAQ PF10205.9 KEY73099.1 - 1.8 8.8 10.3 9.4 6.6 3.3 3.2 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 KEY73099.1 - 2.5 7.1 13.7 1.5 7.8 1.8 2.2 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KEY73099.1 - 2.9 8.4 11.6 3 8.3 0.7 3.6 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KEY73099.1 - 3.5 7.4 9.7 1.2 8.9 0.6 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 KEY73099.1 - 5 6.9 18.5 15 5.4 6.8 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH COG2 PF06148.11 KEY73099.1 - 5 7.2 12.0 0.45 10.6 3.3 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KEY73099.1 - 5.6 7.0 14.0 7.1 6.7 4.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KEY73099.1 - 6.2 7.0 14.7 7.8 6.6 4.5 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 KEY73099.1 - 7 5.8 7.7 5.6 6.1 3.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Fez1 PF06818.15 KEY73099.1 - 9.3 6.6 12.3 23 5.4 11.7 1.9 1 1 0 1 1 1 0 Fez1 Lebercilin PF15619.6 KEY73099.1 - 9.3 5.9 19.2 1.4 8.5 5.0 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2802 PF10975.8 KEY73099.1 - 9.5 6.4 11.7 4.8 7.4 2.6 3.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2802) p450 PF00067.22 KEY73100.1 - 2.3e-49 168.4 0.0 3.6e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CAP PF00188.26 KEY73102.1 - 2.5e-19 70.3 2.9 3.7e-19 69.8 2.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.13 KEY73104.1 - 1.1e-09 38.2 13.1 3.8e-08 33.2 3.7 2.4 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KEY73104.1 - 0.00096 19.1 5.6 0.47 10.5 0.1 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KEY73104.1 - 0.0013 18.7 7.6 0.25 11.4 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KEY73104.1 - 0.13 12.6 6.7 5.2 7.4 1.6 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KEY73104.1 - 0.48 10.2 7.0 13 5.6 4.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Nup54 PF13874.6 KEY73105.1 - 1.9e-38 131.8 0.4 1.9e-38 131.8 0.4 2.2 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KEY73105.1 - 8.5e-16 57.2 4.9 2.2e-15 55.9 4.9 1.8 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DUF4407 PF14362.6 KEY73105.1 - 0.00058 19.3 0.2 0.00058 19.3 0.2 2.4 3 0 0 3 3 2 1 Domain of unknown function (DUF4407) Adhesin_P1_N PF18652.1 KEY73105.1 - 0.0021 18.0 1.7 0.005 16.8 1.7 1.6 1 0 0 1 1 1 1 Adhesin P1 N-terminal domain DivIVA PF05103.13 KEY73105.1 - 0.0041 17.2 1.0 0.0041 17.2 1.0 2.4 2 1 1 3 3 3 1 DivIVA protein LPP PF04728.13 KEY73105.1 - 0.03 14.7 2.8 1.4 9.3 0.0 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper YliH PF10799.8 KEY73105.1 - 0.067 13.1 0.6 0.42 10.5 0.1 2.3 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) Nucleoporin_FG PF13634.6 KEY73105.1 - 0.085 13.7 10.7 0.14 13.0 10.7 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region DUF3782 PF12644.7 KEY73105.1 - 0.2 11.8 1.2 6.3 7.0 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3782) HALZ PF02183.18 KEY73105.1 - 0.3 11.4 4.4 2.3 8.5 0.6 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KEY73105.1 - 0.32 11.1 4.1 3.7 7.7 0.4 3.0 2 0 0 2 2 2 0 bZIP transcription factor CLZ PF16526.5 KEY73105.1 - 0.53 10.7 8.4 0.77 10.2 1.0 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5595 PF18077.1 KEY73105.1 - 0.55 10.3 4.4 0.39 10.8 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) FUSC PF04632.12 KEY73105.1 - 0.61 8.5 4.7 1.1 7.8 4.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family YnfE PF17452.2 KEY73105.1 - 0.66 10.3 5.1 17 5.8 1.9 3.3 3 1 1 4 4 3 0 Uncharacterized YnfE-like YscO-like PF16789.5 KEY73105.1 - 0.79 9.7 7.6 2.1 8.4 2.6 2.6 1 1 1 2 2 2 0 YscO-like protein UPF0184 PF03670.13 KEY73105.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.0 4 0 0 4 4 3 0 Uncharacterised protein family (UPF0184) V_ATPase_I PF01496.19 KEY73105.1 - 1.4 6.7 3.2 1.3 6.9 1.2 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KEY73105.1 - 2.6 7.4 8.8 2.2 7.6 2.2 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KEY73105.1 - 4.4 7.3 11.4 7.9 6.5 1.4 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GDC-P PF02347.16 KEY73106.1 - 6.3e-162 539.3 0.1 6.7e-148 493.1 0.0 2.4 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KEY73106.1 - 1.5e-05 24.5 0.0 3.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase THF_DHG_CYH PF00763.23 KEY73106.1 - 0.015 15.5 0.0 7.3 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.32 KEY73107.1 - 1.4e-15 57.4 10.9 0.0045 17.8 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY73107.1 - 6.7e-06 26.3 0.0 1.7 9.0 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4690 PF15756.5 KEY73107.1 - 0.00028 21.4 4.1 0.00028 21.4 4.1 3.1 3 1 1 4 4 4 1 Small Novel Rich in Cartilage SKG6 PF08693.10 KEY73107.1 - 0.00075 18.9 2.9 0.0018 17.6 2.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PHD PF00628.29 KEY73108.1 - 3.4e-10 39.7 12.1 3.4e-10 39.7 12.1 2.0 2 0 0 2 2 2 1 PHD-finger SCO1-SenC PF02630.14 KEY73109.1 - 5.8e-47 159.0 0.0 7.9e-47 158.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEY73109.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Hydrolase_6 PF13344.6 KEY73110.1 - 6.9e-20 71.1 0.0 1.8e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEY73110.1 - 1.1e-17 63.9 0.0 2.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY73110.1 - 1.9e-07 31.6 0.0 0.61 10.3 0.0 3.3 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY73110.1 - 0.0017 18.8 0.1 2.4 8.5 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEY73110.1 - 0.021 14.9 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 KEY73111.1 - 5e-60 202.7 0.1 1.1e-59 201.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KEY73111.1 - 1.2e-19 69.7 0.0 3e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KEY73111.1 - 1.2e-05 25.3 0.4 1.2e-05 25.3 0.4 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family ApoLp-III PF07464.11 KEY73111.1 - 0.13 12.3 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BTB PF00651.31 KEY73112.1 - 1.7e-24 86.2 0.4 1.7e-12 47.5 0.2 3.4 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 KEY73112.1 - 7.3e-07 29.7 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY73112.1 - 4e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY73112.1 - 1.8e-05 25.2 0.0 5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73112.1 - 0.00024 21.3 0.2 0.31 11.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KEY73112.1 - 0.0089 16.4 0.1 0.15 12.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.25 KEY73113.1 - 1.9e-56 191.4 0.2 2.7e-36 125.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73113.1 - 2.3e-37 128.7 0.0 8.7e-37 126.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY73113.1 - 3.7e-05 23.2 0.0 7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEY73113.1 - 0.015 15.2 1.9 0.034 14.1 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4140 PF13600.6 KEY73113.1 - 0.1 13.1 0.4 0.3 11.5 0.4 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Not3 PF04065.15 KEY73114.1 - 0.0031 17.0 0.9 0.0055 16.2 0.2 1.6 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component Use1 PF09753.9 KEY73114.1 - 0.024 14.3 0.1 0.058 13.1 0.0 1.6 1 1 1 2 2 2 0 Membrane fusion protein Use1 Pox_A_type_inc PF04508.12 KEY73114.1 - 0.049 13.5 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ead_Ea22 PF13935.6 KEY73114.1 - 0.06 14.0 0.2 0.084 13.5 0.2 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein BLOC1_2 PF10046.9 KEY73114.1 - 0.11 12.8 0.6 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C2H2 PF00096.26 KEY73117.1 - 1.7e-09 37.6 7.9 0.00022 21.5 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY73117.1 - 0.00014 22.4 7.3 0.17 12.8 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY73117.1 - 0.00075 19.8 7.7 0.0019 18.5 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KEY73117.1 - 0.0025 18.1 1.7 0.0087 16.4 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEY73117.1 - 0.087 13.1 2.3 0.28 11.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KEY73117.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KEY73117.1 - 1.3 9.1 4.2 3.4 7.8 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger Fungal_trans_2 PF11951.8 KEY73118.1 - 1.5e-31 109.6 0.2 1.8e-31 109.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73118.1 - 2.7e-06 27.4 8.6 4.1e-06 26.8 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Candida_ALS PF05792.13 KEY73119.1 - 6.6e-90 295.3 2610.7 2.9e-05 24.5 13.9 130.4 127 6 0 127 127 127 94 Candida agglutinin-like (ALS) DUF916 PF06030.12 KEY73119.1 - 0.4 10.8 4.0 41 4.3 0.0 5.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF916) Epiglycanin_C PF14654.6 KEY73121.1 - 0.044 13.9 1.1 11 6.2 0.3 2.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region EST1_DNA_bind PF10373.9 KEY73123.1 - 3.5e-09 36.5 0.0 1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain UCR_14kD PF02271.16 KEY73123.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ThiF PF00899.21 KEY73124.1 - 2.5e-42 144.9 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KEY73124.1 - 1.6e-06 28.4 0.0 4.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KEY73124.1 - 0.022 14.4 0.0 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KEY73124.1 - 0.072 13.3 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Melibiase_2 PF16499.5 KEY73124.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A TPR_12 PF13424.6 KEY73125.1 - 0.0078 16.5 0.8 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73125.1 - 4.2 8.5 10.9 4.3 8.4 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Atg29_N PF18388.1 KEY73127.1 - 8.7e-27 92.7 1.6 1.5e-26 92.0 1.6 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Thioredox_DsbH PF03190.15 KEY73129.1 - 6.3e-57 192.1 0.0 1.1e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KEY73129.1 - 0.003 17.7 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like DLIC PF05783.11 KEY73130.1 - 2e-31 109.4 0.0 4e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KEY73131.1 - 3.7e-14 52.3 0.0 7.3e-13 48.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEY73131.1 - 0.013 15.5 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif WD40 PF00400.32 KEY73132.1 - 8.3e-07 29.6 0.1 0.028 15.3 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY73132.1 - 0.0011 19.2 0.0 0.021 15.1 0.0 2.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KEY73132.1 - 0.0041 16.9 0.3 6 6.5 0.0 3.3 3 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.12 KEY73132.1 - 0.006 14.6 0.0 0.024 12.7 0.0 1.8 1 1 1 2 2 2 1 IKI3 family NTPase_I-T PF01931.18 KEY73132.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 Ge1_WD40 PF16529.5 KEY73132.1 - 0.034 13.1 0.0 0.98 8.3 0.0 2.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Septin PF00735.18 KEY73133.1 - 4.3e-108 360.9 0.2 7e-108 360.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KEY73133.1 - 5.8e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY73133.1 - 0.0025 17.8 0.2 0.0025 17.8 0.2 2.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KEY73133.1 - 0.0031 17.6 2.7 1.7 8.6 0.0 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KEY73133.1 - 0.02 14.4 0.7 0.084 12.4 0.1 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KEY73133.1 - 0.035 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEY73133.1 - 0.05 13.9 1.2 0.14 12.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain EB1 PF03271.17 KEY73133.1 - 0.082 13.2 1.4 3.5 8.0 1.3 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif Ribosomal_S17e PF00833.18 KEY73133.1 - 0.61 10.0 3.7 1.6 8.7 3.7 1.7 1 0 0 1 1 1 0 Ribosomal S17 Bax1-I PF01027.20 KEY73134.1 - 3.9e-51 173.8 24.5 4.5e-51 173.6 24.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 KEY73134.1 - 0.47 10.6 7.3 1.2 9.2 7.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5504) TRAM_LAG1_CLN8 PF03798.16 KEY73135.1 - 5.3e-48 163.4 19.3 9.3e-48 162.6 19.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KEY73135.1 - 3.3e-19 68.3 0.2 3.3e-19 68.3 0.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein AMP-binding PF00501.28 KEY73136.1 - 1.5e-83 280.8 0.0 1.9e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEY73136.1 - 8.4e-19 68.3 0.0 2.3e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 KEY73137.1 - 1.8e-15 57.4 0.0 3.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.20 KEY73138.1 - 5.9e-153 509.6 0.0 7.8e-153 509.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KEY73138.1 - 3.3e-06 27.2 0.0 6.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KEY73138.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain pP_pnuc_1 PF18165.1 KEY73138.1 - 0.21 11.5 0.2 2.7 7.9 0.0 2.6 3 0 0 3 3 3 0 Predicted pPIWI-associating nuclease QRPTase_C PF01729.19 KEY73139.1 - 8.4e-57 191.6 0.1 1e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KEY73139.1 - 1.5e-16 60.2 0.1 6.9e-16 58.1 0.0 2.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Mannosyl_trans3 PF11051.8 KEY73140.1 - 0.0055 16.1 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Tim54 PF11711.8 KEY73140.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TPR_1 PF00515.28 KEY73141.1 - 1.1e-12 47.2 2.0 1.5e-06 27.8 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73141.1 - 3.3e-12 45.5 11.5 7.6e-07 28.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73141.1 - 4.5e-09 36.5 7.0 0.17 12.2 0.6 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEY73141.1 - 4.3e-07 29.5 3.6 0.077 12.7 0.0 6.2 7 0 0 7 7 7 1 TPR repeat TPR_19 PF14559.6 KEY73141.1 - 7.2e-06 26.4 9.2 0.039 14.5 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73141.1 - 7.7e-06 25.7 3.4 0.046 14.0 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73141.1 - 0.00019 22.0 11.4 1.3 10.1 0.0 7.6 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73141.1 - 0.0011 18.8 1.5 0.48 10.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73141.1 - 0.0015 19.1 14.8 0.44 11.2 0.0 7.4 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73141.1 - 0.015 15.6 4.5 21 5.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY73141.1 - 0.03 14.9 1.4 92 4.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEY73141.1 - 0.086 13.0 0.1 9.6 6.4 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY73141.1 - 8.7 6.4 8.9 76 3.4 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Metallophos PF00149.28 KEY73142.1 - 3.8e-14 53.7 0.1 6e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY73142.1 - 0.003 17.8 0.0 0.046 13.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain LigB PF02900.18 KEY73144.1 - 1.7e-32 112.6 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase IMD PF08397.11 KEY73146.1 - 1e-05 25.0 3.3 0.00092 18.7 0.9 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain CIDE-N PF02017.15 KEY73146.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 CIDE-N domain Abhydrolase_2 PF02230.16 KEY73147.1 - 8.3e-45 153.2 0.0 1e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KEY73147.1 - 2.6e-09 36.7 0.5 0.038 13.2 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 KEY73147.1 - 2.6e-07 30.6 0.0 6.6e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KEY73147.1 - 3.5e-06 26.8 0.2 4.1e-05 23.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY73147.1 - 1e-05 25.1 0.0 8.6e-05 22.1 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY73147.1 - 0.00022 21.9 0.0 0.0012 19.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KEY73147.1 - 0.00047 19.8 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 KEY73147.1 - 0.05 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.16 KEY73147.1 - 0.1 12.2 0.1 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Cutinase PF01083.22 KEY73147.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase AXE1 PF05448.12 KEY73147.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KEY73147.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase PE-PPE PF08237.11 KEY73147.1 - 0.2 11.2 0.0 0.47 10.0 0.1 1.5 2 0 0 2 2 2 0 PE-PPE domain LRR_4 PF12799.7 KEY73148.1 - 5.8e-07 29.7 4.4 0.0002 21.7 0.5 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY73148.1 - 7.7e-06 25.6 3.3 5.6e-05 22.8 0.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KEY73148.1 - 6.2 7.8 6.9 5.1 8.0 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Phosducin PF02114.16 KEY73149.1 - 5e-11 42.0 0.0 7.3e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KEY73149.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S27e PF01667.17 KEY73150.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KEY73150.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding RNR_inhib PF08591.10 KEY73151.1 - 3.4e-32 111.9 0.2 3.3e-31 108.8 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor COX16 PF14138.6 KEY73152.1 - 1.1e-30 106.0 0.1 1.5e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 FAD_binding_3 PF01494.19 KEY73155.1 - 4.7e-07 29.4 0.0 3.1e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Pkinase PF00069.25 KEY73155.1 - 2.3e-05 23.9 0.0 0.00099 18.5 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.14 KEY73155.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KEY73155.1 - 0.039 13.2 0.0 6.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 KEY73155.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2949 PF11165.8 KEY73155.1 - 0.071 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) FAD_binding_4 PF01565.23 KEY73156.1 - 3.1e-21 75.6 1.8 3.1e-21 75.6 1.8 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY73156.1 - 2.5e-12 46.7 1.5 6.2e-11 42.2 0.3 2.4 2 0 0 2 2 2 1 Berberine and berberine like MccV PF17508.2 KEY73156.1 - 1.3 9.6 7.0 1.8 9.1 0.3 3.4 3 0 0 3 3 3 0 Microcin V bacteriocin Alpha-amylase PF00128.24 KEY73157.1 - 7.6e-20 71.7 0.1 3.5e-19 69.5 0.1 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KEY73157.1 - 1.1e-10 41.8 0.1 2.6e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain SpoU_methylas_C PF12105.8 KEY73157.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal adh_short PF00106.25 KEY73158.1 - 3.5e-39 134.3 0.0 4.7e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73158.1 - 1.5e-22 80.3 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY73158.1 - 4.1e-08 33.0 0.2 1.8e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY73158.1 - 8.6e-07 29.0 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEY73158.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEY73158.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 KEY73158.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KEY73158.1 - 0.062 12.4 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEY73158.1 - 0.17 11.2 0.5 1.6 8.0 0.5 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KEY73159.1 - 0.043 12.8 1.0 0.083 11.9 0.1 1.9 2 1 0 2 2 2 0 Fungal specific transcription factor domain Methyltransf_12 PF08242.12 KEY73161.1 - 7.7e-20 71.5 0.0 1.9e-19 70.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY73161.1 - 8.2e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73161.1 - 1.3e-11 45.0 0.0 2.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73161.1 - 9.9e-11 41.7 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73161.1 - 7.7e-10 39.3 0.0 2e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY73161.1 - 1.9e-05 24.1 0.0 0.00011 21.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEY73161.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase CTC1 PF15489.6 KEY73161.1 - 0.2 9.1 0.1 0.29 8.6 0.1 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 p450 PF00067.22 KEY73162.1 - 5.7e-54 183.6 0.0 7.2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.27 KEY73163.1 - 9.6e-11 41.1 5.7 1.7e-10 40.3 5.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 KEY73163.1 - 0.056 13.4 1.4 0.14 12.1 1.4 1.7 1 0 0 1 1 1 0 Nudix N-terminal Pkinase PF00069.25 KEY73164.1 - 7.1e-26 91.1 0.0 2.1e-15 56.8 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73164.1 - 8.5e-08 31.8 0.0 0.0026 17.1 0.0 3.8 3 1 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 KEY73164.1 - 0.0094 15.3 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEY73164.1 - 0.019 14.9 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEY73164.1 - 0.02 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 KEY73165.1 - 4.9e-30 104.5 0.0 6.1e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73165.1 - 1.6e-29 103.1 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KEY73166.1 - 4.2e-28 98.3 0.0 2e-27 96.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_10 PF13673.7 KEY73167.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY73167.1 - 0.0036 17.5 0.2 0.0069 16.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Zn_clus PF00172.18 KEY73168.1 - 1.8e-06 28.0 10.4 3e-06 27.2 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY73168.1 - 7.3e-05 21.7 1.3 0.00014 20.8 1.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.27 KEY73169.1 - 2.3e-49 167.4 0.0 1e-28 100.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEY73169.1 - 3.6e-33 115.4 25.9 1.8e-24 86.9 14.4 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KEY73169.1 - 9.4e-07 28.9 0.3 0.015 15.1 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEY73169.1 - 1.1e-06 28.3 8.4 0.08 12.4 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY73169.1 - 4.4e-06 27.2 0.2 0.087 13.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEY73169.1 - 7.6e-06 25.6 0.4 0.046 13.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEY73169.1 - 2.9e-05 24.1 0.6 0.031 14.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEY73169.1 - 5.1e-05 23.6 1.8 0.043 14.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEY73169.1 - 5.1e-05 22.5 0.1 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KEY73169.1 - 7.7e-05 23.3 1.4 0.12 12.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KEY73169.1 - 0.00062 19.8 0.1 1.1 9.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 KEY73169.1 - 0.001 18.3 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MeaB PF03308.16 KEY73169.1 - 0.0021 17.1 0.9 0.028 13.4 0.0 2.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KEY73169.1 - 0.005 16.4 0.3 0.75 9.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KEY73169.1 - 0.0087 16.5 0.0 0.22 11.9 0.0 2.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KEY73169.1 - 0.013 15.3 0.2 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KEY73169.1 - 0.014 15.8 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 KEY73169.1 - 0.014 15.0 0.1 0.26 10.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEY73169.1 - 0.016 14.9 0.8 9.8 5.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEY73169.1 - 0.022 14.5 5.8 1.4 8.6 0.2 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF87 PF01935.17 KEY73169.1 - 0.023 14.8 1.4 0.057 13.5 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KEY73169.1 - 0.025 14.3 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEY73169.1 - 0.035 13.3 0.3 8.9 5.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KEY73169.1 - 0.049 13.2 0.1 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KEY73169.1 - 0.053 13.8 0.5 7.3 6.9 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEY73169.1 - 0.075 13.2 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KEY73169.1 - 0.11 12.1 1.2 0.59 9.8 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KEY73169.1 - 0.12 12.1 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KEY73169.1 - 0.12 11.7 0.0 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KEY73169.1 - 0.12 12.4 2.2 4.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KEY73169.1 - 0.13 12.1 1.0 13 5.6 0.1 2.4 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KEY73169.1 - 0.16 10.8 0.2 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KEY73169.1 - 0.16 11.8 0.7 8.1 6.3 0.1 2.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KEY73169.1 - 0.23 10.8 0.6 15 4.8 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 KEY73169.1 - 0.33 10.8 0.9 1.1 9.1 0.0 2.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AMP-binding PF00501.28 KEY73170.1 - 0 1292.2 1.8 5.9e-80 268.9 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KEY73170.1 - 0 1201.0 0.0 2.5e-60 204.5 0.0 12.9 12 3 0 12 12 12 11 Condensation domain PP-binding PF00550.25 KEY73170.1 - 2.3e-68 226.5 4.6 8.2e-11 42.1 0.2 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site Transferase PF02458.15 KEY73170.1 - 3.9e-14 52.1 0.0 0.002 16.8 0.0 5.7 5 0 0 5 5 5 5 Transferase family AMP-binding_C PF13193.6 KEY73170.1 - 6.5e-11 43.0 0.0 3.2 8.8 0.0 6.1 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain AATase PF07247.12 KEY73170.1 - 0.029 13.0 0.3 5.7 5.4 0.0 3.9 4 0 0 4 4 4 0 Alcohol acetyltransferase Glyco_hydro_18 PF00704.28 KEY73171.1 - 1.9e-56 192.1 0.0 2.7e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY73171.1 - 1.2e-11 44.8 35.0 1.1e-09 38.6 10.5 3.2 2 0 0 2 2 2 2 Chitin recognition protein DNase_NucA_NucB PF14040.6 KEY73171.1 - 0.00014 22.2 0.5 0.00044 20.6 0.1 2.0 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.19 KEY73172.1 - 3.5e-09 37.0 64.7 0.0005 20.5 14.6 3.7 3 0 0 3 3 3 3 Chitin recognition protein F-box-like PF12937.7 KEY73172.1 - 1.4e-06 28.1 0.1 5.5e-06 26.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY73172.1 - 0.1 12.5 0.3 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 F-box domain ACP_syn_III_C PF08541.10 KEY73172.1 - 0.22 11.7 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LysM PF01476.20 KEY73173.1 - 7.9e-07 29.0 0.2 0.046 13.8 0.0 3.7 4 0 0 4 4 4 2 LysM domain CorA PF01544.18 KEY73174.1 - 2.9e-08 33.4 0.9 4.2e-08 32.8 0.9 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Egh16-like PF11327.8 KEY73174.1 - 0.0011 19.4 2.7 0.0037 17.7 2.7 1.7 1 1 0 1 1 1 1 Egh16-like virulence factor HATPase_c PF02518.26 KEY73175.1 - 4.1e-22 78.8 0.0 8.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY73175.1 - 1.9e-19 69.9 0.0 3.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY73175.1 - 2.7e-09 36.9 0.1 7.9e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Glyco_hydro_61 PF03443.14 KEY73176.1 - 1.2e-69 234.4 0.0 1.4e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 KEY73177.1 - 9.9e-32 110.3 1.9 2.2e-31 109.2 1.9 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSH_synthase PF03199.15 KEY73177.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic glutathione synthase SUKH-3 PF14433.6 KEY73177.1 - 0.052 14.0 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 SUKH-3 immunity protein Sugar_tr PF00083.24 KEY73178.1 - 2.7e-73 247.4 29.6 3.1e-73 247.2 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73178.1 - 2.3e-15 56.4 34.0 2.3e-15 56.4 34.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Ndc1_Nup PF09531.10 KEY73178.1 - 4.3 5.9 5.5 7.2 5.2 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_clus PF00172.18 KEY73179.1 - 1.1e-08 35.0 10.3 2.4e-08 33.9 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 KEY73180.1 - 1.8e-33 116.2 0.1 2.9e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.18 KEY73180.1 - 1.4e-09 37.4 0.1 2.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73180.1 - 3.4e-09 36.7 8.3 3.4e-09 36.7 8.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_42 PF02449.15 KEY73180.1 - 0.049 13.0 0.2 0.37 10.1 0.1 2.0 1 1 0 2 2 2 0 Beta-galactosidase Fungal_trans_2 PF11951.8 KEY73180.1 - 0.068 12.0 1.1 0.43 9.3 0.2 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain PhyH PF05721.13 KEY73180.1 - 0.16 12.2 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short_C2 PF13561.6 KEY73181.1 - 1.3e-32 113.2 0.0 1.9e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY73181.1 - 5.2e-19 68.5 0.0 6.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY73181.1 - 2.2e-05 24.4 0.2 3.4e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KEY73181.1 - 0.041 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.18 KEY73182.1 - 1.3e-24 86.7 0.1 1.8e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73182.1 - 9.3e-05 22.5 7.5 0.00019 21.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 KEY73183.1 - 1.8e-109 366.5 36.4 2e-109 366.3 36.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amido_AtzD_TrzD PF09663.10 KEY73184.1 - 1.4e-111 373.1 4.9 1.2e-104 350.3 3.2 2.1 2 0 0 2 2 2 2 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Amidase PF01425.21 KEY73185.1 - 1.2e-71 242.1 0.3 2.9e-71 240.8 0.3 1.6 1 1 0 1 1 1 1 Amidase APH PF01636.23 KEY73186.1 - 5.8e-07 29.7 1.5 2e-05 24.6 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEY73186.1 - 3e-05 23.5 0.0 5.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KEY73186.1 - 0.00014 21.3 0.3 0.0013 18.1 0.2 2.4 1 1 1 2 2 2 1 Protein kinase domain Seadorna_VP7 PF07387.11 KEY73186.1 - 0.0038 16.3 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KEY73186.1 - 0.005 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KEY73186.1 - 0.0056 16.3 0.0 2.5 7.6 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Zn_clus PF00172.18 KEY73187.1 - 0.1 12.7 8.6 0.23 11.6 8.6 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY73188.1 - 1e-18 67.4 0.2 1.8e-18 66.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY73189.1 - 1.5e-30 106.4 23.7 2.3e-30 105.7 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Zeta_toxin PF06414.12 KEY73189.1 - 0.00076 18.8 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KEY73189.1 - 0.00094 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KEY73189.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 KEY73189.1 - 0.015 15.7 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KEY73189.1 - 0.024 15.2 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KEY73189.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ParA PF10609.9 KEY73189.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NACHT PF05729.12 KEY73189.1 - 0.2 11.6 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Iso_dh PF00180.20 KEY73190.1 - 3.8e-84 282.8 0.0 4.3e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTS_EIIC_2 PF13303.6 KEY73190.1 - 0.074 12.1 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4875 PF16175.5 KEY73190.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Glyco_hydro_3_C PF01915.22 KEY73191.1 - 6.1e-52 176.5 0.0 1.1e-51 175.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY73191.1 - 6.1e-41 140.8 0.0 9.3e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY73191.1 - 1.8e-24 85.6 0.0 4.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 KEY73191.1 - 1.6e-11 44.0 16.2 1.6e-11 44.0 16.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain CK1gamma_C PF12605.8 KEY73191.1 - 0.03 15.5 2.6 0.048 14.8 1.2 2.0 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal MGC-24 PF05283.11 KEY73191.1 - 3.4 8.1 11.3 11 6.5 11.3 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_43 PF04616.14 KEY73192.1 - 6.8e-56 189.7 3.5 8e-56 189.5 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KEY73192.1 - 0.023 14.3 0.3 0.044 13.4 0.2 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_61 PF03443.14 KEY73193.1 - 9.4e-64 215.1 0.0 1.3e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_35 PF01301.19 KEY73194.1 - 3.8e-84 283.0 0.1 5.5e-83 279.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KEY73194.1 - 1.2e-59 201.1 0.2 2.6e-59 200.1 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KEY73194.1 - 6.8e-49 165.2 1.9 2.8e-23 82.7 0.6 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KEY73194.1 - 4.2e-23 80.7 0.0 1.2e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 CorA PF01544.18 KEY73195.1 - 1.1e-11 44.7 0.2 1.8e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 KEY73196.1 - 4.2e-79 266.5 13.5 4.9e-79 266.3 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73196.1 - 3.7e-28 98.5 13.0 3.7e-28 98.5 13.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEY73196.1 - 0.00029 19.3 5.3 0.016 13.6 0.5 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.26 KEY73198.1 - 4.9e-73 245.8 0.0 1.1e-72 244.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY73198.1 - 2.3e-54 184.0 0.1 9.1e-50 169.1 0.0 2.7 2 0 0 2 2 2 2 KR domain PS-DH PF14765.6 KEY73198.1 - 2.5e-35 122.2 0.3 2e-34 119.2 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 KEY73198.1 - 1.5e-34 119.4 0.0 2.6e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KEY73198.1 - 6.2e-33 114.7 0.0 1.9e-32 113.0 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY73198.1 - 2.3e-30 105.0 0.0 7e-30 103.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEY73198.1 - 2e-17 63.8 0.0 5.1e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEY73198.1 - 3.4e-13 49.5 0.0 3.9e-12 46.0 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KEY73198.1 - 4.7e-12 46.4 0.0 2.3e-10 41.0 0.0 3.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY73198.1 - 7.2e-12 45.8 0.0 1.9e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KEY73198.1 - 1e-09 38.4 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEY73198.1 - 3e-09 36.7 0.1 2.9e-05 23.7 0.1 3.5 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KEY73198.1 - 3.5e-08 34.0 0.0 1.7e-07 31.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY73198.1 - 1.9e-06 27.4 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KEY73198.1 - 2.7e-06 27.0 0.0 6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KEY73198.1 - 1.8e-05 24.6 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KEY73198.1 - 2.1e-05 23.7 0.0 0.00038 19.5 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KEY73198.1 - 2.2e-05 24.2 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KEY73198.1 - 0.0035 16.8 0.0 0.66 9.3 0.0 2.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ACP_syn_III PF08545.10 KEY73198.1 - 0.0099 15.7 0.1 0.033 14.0 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NmrA PF05368.13 KEY73198.1 - 0.076 12.6 0.0 0.4 10.2 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Methyltransf_33 PF10017.9 KEY73198.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 KEY73198.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.26 KEY73199.1 - 4.2e-06 26.8 0.1 1.2e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY73199.1 - 0.0071 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain BCHF PF07284.11 KEY73199.1 - 0.084 12.9 3.4 0.22 11.5 3.4 1.7 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) ADH_zinc_N_2 PF13602.6 KEY73199.1 - 0.12 13.5 0.0 0.29 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 KEY73200.1 - 1.9e-22 79.7 0.0 3.1e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73200.1 - 3e-14 53.1 0.0 2e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73200.1 - 4.6e-08 33.2 0.1 7.4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY73200.1 - 0.00032 20.3 0.1 0.00041 19.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KEY73201.1 - 1.7e-19 69.9 2.6 2.3e-19 69.5 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY73201.1 - 3.6e-09 36.6 2.6 7.7e-09 35.5 2.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sulfotransfer_4 PF17784.1 KEY73202.1 - 2.4e-66 223.7 0.1 2.8e-66 223.4 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY73202.1 - 0.00014 22.3 0.1 0.031 14.7 0.1 2.6 1 1 1 2 2 2 1 Sulfotransferase family GMC_oxred_C PF05199.13 KEY73203.1 - 4.1e-24 85.7 0.0 6.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEY73204.1 - 4.8e-39 134.5 0.0 2.6e-29 102.5 0.0 2.0 1 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY73204.1 - 1.7e-08 33.9 0.3 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEY73204.1 - 2.1e-07 30.9 0.2 0.0021 17.7 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY73204.1 - 1.6e-05 24.2 0.1 2.4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEY73204.1 - 4.6e-05 23.6 0.1 0.00014 22.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY73204.1 - 5.3e-05 22.6 0.6 0.054 12.7 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY73204.1 - 8.3e-05 21.9 0.1 0.00017 20.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEY73204.1 - 0.0025 17.1 0.0 0.072 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY73204.1 - 0.018 13.8 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEY73204.1 - 0.099 11.9 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KEY73204.1 - 0.11 11.6 0.0 10 5.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KEY73204.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase adh_short PF00106.25 KEY73205.1 - 2.7e-26 92.2 1.2 4.8e-22 78.4 0.6 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73205.1 - 5e-18 65.5 1.8 3e-17 63.0 1.9 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KEY73205.1 - 1.4e-05 25.1 1.1 2.5e-05 24.3 1.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY73205.1 - 0.00039 20.4 0.5 0.00059 19.8 0.5 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KEY73205.1 - 0.022 14.4 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.10 KEY73205.1 - 0.16 11.3 0.0 5 6.4 0.0 2.6 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) Rhodanese PF00581.20 KEY73206.1 - 4.6e-18 65.7 0.0 5.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain ADH_zinc_N PF00107.26 KEY73207.1 - 1.1e-09 38.3 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY73207.1 - 7.6e-08 32.2 0.1 2.5e-07 30.6 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY73207.1 - 0.006 17.6 0.0 0.012 16.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY73208.1 - 6.3e-37 126.9 0.0 1.4e-36 125.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73208.1 - 8.7e-24 84.4 0.0 1.1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KEY73208.1 - 8.3e-07 28.7 0.0 1.3e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KEY73208.1 - 0.0053 16.7 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KEY73208.1 - 0.015 14.8 0.1 0.031 13.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEY73209.1 - 2.2e-34 118.6 0.1 3e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73209.1 - 5e-26 91.7 0.1 6.5e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY73209.1 - 4.8e-06 26.2 0.0 9.8e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY73209.1 - 0.00017 21.6 0.2 0.0025 17.8 0.0 2.1 2 0 0 2 2 2 1 KR domain DFP PF04127.15 KEY73209.1 - 0.0098 15.7 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KEY73209.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 KEY73210.1 - 1.4e-36 126.1 56.3 4.8e-36 124.4 53.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY73210.1 - 1.1e-14 53.8 23.0 1.1e-13 50.5 23.0 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3377 PF11857.8 KEY73210.1 - 0.42 10.6 1.2 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Saf_2TM PF18303.1 KEY73210.1 - 2.5 7.7 5.7 0.91 9.1 0.6 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Fungal_trans PF04082.18 KEY73211.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73211.1 - 0.00037 20.6 13.0 0.00086 19.4 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEY73212.1 - 6.5e-63 213.1 0.0 9.9e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KEY73214.1 - 4.2e-13 49.5 0.2 3.9e-11 43.1 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY73214.1 - 2.5e-07 30.2 0.0 4.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 KEY73214.1 - 8.9e-05 21.5 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KEY73214.1 - 0.0073 15.8 0.0 0.061 12.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEY73214.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NAD_binding_10 PF13460.6 KEY73215.1 - 1.6e-07 31.4 0.1 1.6e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEY73215.1 - 0.00014 21.4 0.1 0.00015 21.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KEY73215.1 - 0.00016 21.2 0.1 0.00019 21.0 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEY73215.1 - 0.00046 19.8 0.1 0.00048 19.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KEY73215.1 - 0.0015 18.4 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KEY73215.1 - 0.0022 17.0 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KEY73215.1 - 0.0053 17.0 0.0 0.0059 16.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KEY73215.1 - 0.046 13.8 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KEY73215.1 - 0.062 13.4 0.1 0.08 13.1 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KEY73216.1 - 0.0033 17.0 0.0 0.0038 16.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family p450 PF00067.22 KEY73217.1 - 5.2e-42 144.2 0.0 7.6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY73218.1 - 7.9e-44 150.1 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3237 PF11578.8 KEY73219.1 - 1.9e-30 105.7 0.0 2.1e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GDPD_2 PF13653.6 KEY73219.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family p450 PF00067.22 KEY73220.1 - 3.7e-69 233.7 0.0 4.4e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEY73221.1 - 1.8e-05 24.7 11.4 3.9e-05 23.7 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RLL PF10036.9 KEY73221.1 - 0.055 13.3 0.4 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF5446 PF17522.2 KEY73221.1 - 0.056 13.6 0.2 0.45 10.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) p450 PF00067.22 KEY73222.1 - 2.1e-66 224.6 0.0 2.7e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF3_p135 PF12807.7 KEY73222.1 - 0.099 12.7 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Transferase PF02458.15 KEY73223.1 - 1.8e-20 73.0 0.0 4.5e-11 42.1 0.0 3.0 3 0 0 3 3 3 3 Transferase family adh_short PF00106.25 KEY73224.1 - 3e-36 124.7 0.1 4.3e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73224.1 - 1.6e-25 90.1 0.1 2.2e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY73224.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY73224.1 - 0.0016 18.3 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 KEY73224.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 KEY73224.1 - 0.021 14.8 0.1 0.064 13.2 0.1 1.8 1 1 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 KEY73224.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KEY73224.1 - 0.17 10.5 0.5 0.25 10.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KEY73224.1 - 0.19 10.7 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.23 KEY73225.1 - 8.2e-21 74.2 0.8 1.3e-20 73.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain PSD2 PF07624.11 KEY73226.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) adh_short PF00106.25 KEY73227.1 - 2.1e-25 89.4 0.0 1.1e-24 86.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73227.1 - 5.5e-19 68.7 0.0 1.3e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73227.1 - 2.7e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY73227.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY73227.1 - 0.0057 16.6 0.1 0.0091 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Rubella_E2 PF05749.11 KEY73229.1 - 0.00044 19.8 2.0 0.00067 19.2 2.0 1.3 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 Dimer_Tnp_hAT PF05699.14 KEY73232.1 - 4.8e-16 58.3 0.2 1.5e-15 56.8 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region APH PF01636.23 KEY73236.1 - 1.5e-08 34.9 0.0 8.5e-08 32.4 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KEY73236.1 - 0.032 13.4 0.0 0.078 12.2 0.0 1.6 1 0 0 1 1 1 0 Fructosamine kinase DUF2465 PF10239.9 KEY73236.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) SUR7 PF06687.12 KEY73237.1 - 9.5e-18 64.6 6.9 1.2e-17 64.2 6.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KEY73237.1 - 0.01 15.8 4.6 0.02 14.9 4.6 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 bZIP_1 PF00170.21 KEY73238.1 - 0.019 15.0 1.6 0.034 14.2 1.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KEY73238.1 - 0.18 11.9 2.5 0.3 11.2 2.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DDE_Tnp_1_7 PF13843.6 KEY73241.1 - 3e-09 36.7 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Helo_like_N PF17111.5 KEY73243.1 - 5.9e-79 264.3 3.0 1.3e-75 253.3 0.5 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF3829 PF12889.7 KEY73243.1 - 0.0019 17.7 0.2 1.7 8.1 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3829) DASH_Dad2 PF08654.10 KEY73243.1 - 0.026 14.9 2.0 0.082 13.3 0.1 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF5082 PF16888.5 KEY73243.1 - 0.038 14.3 1.9 1.1 9.5 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) GIT_CC PF16559.5 KEY73243.1 - 0.1 12.5 1.2 2.9 7.8 0.0 3.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor NPV_P10 PF05531.12 KEY73243.1 - 0.66 10.5 5.7 12 6.4 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Helo_like_N PF17111.5 KEY73245.1 - 1.5e-57 194.3 12.1 7.9e-56 188.7 2.3 2.8 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEY73245.1 - 4.9e-05 23.5 0.0 4.9e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 KEY73246.1 - 8.3e-33 112.8 0.0 2.4e-12 47.3 0.0 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY73246.1 - 5.2e-17 61.7 0.0 0.0027 18.0 0.0 5.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73246.1 - 2.9e-15 54.8 0.0 0.033 14.7 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KEY73246.1 - 8.7e-13 48.1 0.1 0.052 14.0 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KEY73246.1 - 7.5e-12 45.5 0.0 0.00012 22.6 0.0 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KEY73246.1 - 0.048 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Nrap_D2 PF17403.2 KEY73246.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Glycos_transf_3 PF00591.21 KEY73246.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain DUF3741 PF12552.8 KEY73246.1 - 0.14 12.2 0.4 0.37 10.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) HeLo PF14479.6 KEY73249.1 - 2.9e-35 122.0 0.0 5e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation zf-GRF PF06839.12 KEY73249.1 - 1.6e-05 24.9 1.5 1.6e-05 24.9 1.5 2.6 2 0 0 2 2 2 1 GRF zinc finger LpqV PF17301.2 KEY73249.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative lipoprotein LpqV zf-C2HC5 PF06221.13 KEY73249.1 - 0.13 12.3 0.5 0.39 10.8 0.5 1.8 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FdhE PF04216.12 KEY73249.1 - 0.13 12.1 0.7 0.3 10.9 0.7 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation tRNA-synt_1f PF01921.18 KEY73249.1 - 0.24 10.3 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF3906 PF13046.6 KEY73250.1 - 0.026 14.6 0.0 83 3.4 0.0 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF3906) NPP1 PF05630.11 KEY73250.1 - 0.033 14.3 0.1 19 5.3 0.1 3.2 1 1 1 2 2 2 0 Necrosis inducing protein (NPP1) FAD_binding_4 PF01565.23 KEY73253.1 - 3.2e-21 75.5 0.5 5.5e-21 74.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY73253.1 - 0.00029 20.9 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KEY73253.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 KEY73253.1 - 0.21 11.0 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding VSP PF03302.13 KEY73257.1 - 1.7e-06 27.2 0.1 2.5e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KEY73257.1 - 7.2e-06 26.2 0.2 1.2e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KEY73257.1 - 0.0056 16.0 5.2 0.01 15.2 5.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CEND1 PF15677.5 KEY73257.1 - 0.024 15.2 0.4 0.053 14.1 0.4 1.6 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 SARAF PF06682.12 KEY73257.1 - 0.029 14.0 4.6 0.32 10.6 4.3 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4690 PF15756.5 KEY73257.1 - 0.071 13.7 0.7 0.14 12.8 0.1 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Amnionless PF14828.6 KEY73257.1 - 0.084 11.7 0.1 0.21 10.4 0.0 1.6 1 1 0 2 2 2 0 Amnionless DUF4366 PF14283.6 KEY73257.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PARM PF17061.5 KEY73257.1 - 0.41 10.7 8.3 0.5 10.5 1.2 2.3 2 0 0 2 2 2 0 PARM PAP2_3 PF14378.6 KEY73258.1 - 1.8e-34 119.1 18.0 2.6e-27 95.8 4.8 3.1 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 KEY73258.1 - 0.013 15.3 3.9 0.013 15.3 3.9 2.6 2 1 0 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 KEY73258.1 - 1.4 9.5 5.6 0.42 11.2 0.7 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RabGAP-TBC PF00566.18 KEY73259.1 - 4.3e-35 121.3 1.4 4.3e-35 121.3 1.4 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KEY73259.1 - 9.3e-08 31.7 0.0 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 2 Rab-binding domain (RBD) Mso1_Sec1_bdg PF14475.6 KEY73260.1 - 8.8e-20 70.0 0.1 1.6e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KEY73261.1 - 1.6e-40 138.4 2.7 3e-40 137.5 2.7 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KEY73261.1 - 1e-26 93.4 13.1 1e-26 93.4 13.1 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KEY73261.1 - 2.1e-05 24.0 11.7 2.8e-05 23.7 11.7 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KEY73261.1 - 0.0016 18.3 1.1 0.0026 17.5 1.1 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain LTV PF04180.14 KEY73261.1 - 0.0063 16.3 13.4 0.0077 16.0 13.4 1.2 1 0 0 1 1 1 1 Low temperature viability protein TFIIF_alpha PF05793.12 KEY73261.1 - 0.036 12.7 18.1 0.041 12.5 18.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KIND PF16474.5 KEY73261.1 - 0.9 9.4 10.4 1.9 8.4 10.4 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Vps55 PF04133.14 KEY73262.1 - 2.8e-44 149.8 8.3 3.1e-44 149.7 8.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.7 KEY73262.1 - 5.5 6.0 11.3 7 5.6 11.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Chorismate_bind PF00425.18 KEY73263.1 - 5.8e-71 239.1 0.0 1.7e-70 237.6 0.0 1.7 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KEY73263.1 - 2.8e-23 82.7 0.0 8e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KEY73263.1 - 1e-11 45.2 0.0 1.1e-10 41.9 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KEY73263.1 - 3.7e-05 23.6 0.4 0.00036 20.4 0.4 2.1 1 1 0 1 1 1 1 Peptidase C26 TRAPPC9-Trs120 PF08626.11 KEY73264.1 - 0 1387.9 0.0 0 1387.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KEY73264.1 - 0.043 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.25 KEY73265.1 - 6.7e-20 71.4 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73265.1 - 2.3e-16 60.1 0.0 4.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KEY73265.1 - 0.0054 16.1 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KEY73265.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 KR domain Sugar_tr PF00083.24 KEY73266.1 - 7.1e-114 381.1 31.1 8.1e-114 380.9 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73266.1 - 3.5e-19 69.0 34.5 3.5e-19 69.0 34.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 KEY73268.1 - 1.6e-134 448.5 0.3 2.1e-134 448.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) SNRNP27 PF08648.12 KEY73269.1 - 6.7e-29 99.7 1.1 1.3e-28 98.8 1.1 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Glyco_hydro_63 PF03200.16 KEY73270.1 - 9e-166 552.4 0.0 1.6e-164 548.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KEY73270.1 - 8.4e-74 248.5 0.6 2.1e-73 247.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KEY73270.1 - 4e-05 22.6 0.0 7.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Trehalase MnmE_helical PF12631.7 KEY73272.1 - 2.9e-33 115.8 0.9 3.5e-33 115.5 0.9 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KEY73272.1 - 2.2e-23 82.7 0.0 6.6e-23 81.2 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KEY73272.1 - 3.9e-19 68.8 0.0 1e-18 67.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY73272.1 - 1.8e-05 24.3 0.0 3.9e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEY73272.1 - 0.00014 21.8 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEY73272.1 - 0.00031 20.3 0.0 0.0055 16.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEY73272.1 - 0.00065 19.8 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Dynamin family AAA_24 PF13479.6 KEY73272.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY73272.1 - 0.027 15.0 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KEY73272.1 - 0.056 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4404 PF14357.6 KEY73272.1 - 0.088 13.5 3.3 12 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF3744 PF12558.8 KEY73272.1 - 0.094 13.5 0.0 0.27 12.0 0.0 1.8 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter AIG1 PF04548.16 KEY73272.1 - 0.18 11.1 0.3 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KEY73272.1 - 0.22 11.8 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Proteasome PF00227.26 KEY73273.1 - 6.4e-49 166.0 0.2 8.3e-49 165.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEY73273.1 - 4.9e-11 42.1 0.2 7.9e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 KEY73274.1 - 1.4e-27 96.4 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEY73274.1 - 1.7e-06 27.7 0.7 8.2e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 SLOG cluster4 family CLPTM1 PF05602.12 KEY73275.1 - 9.4e-149 496.1 0.0 1.1e-148 495.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) zf-Di19 PF05605.12 KEY73276.1 - 0.00071 19.8 0.3 0.46 10.8 0.0 3.1 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Longin PF13774.6 KEY73277.1 - 4.1e-26 90.8 0.2 6.8e-26 90.1 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KEY73277.1 - 4.3e-14 52.1 0.0 1.1e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 KEY73277.1 - 0.0051 16.6 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5435) DUF1664 PF07889.12 KEY73277.1 - 0.044 13.8 0.6 0.7 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Paf67 PF10255.9 KEY73277.1 - 0.085 11.8 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 Sirohm_synth_C PF14823.6 KEY73277.1 - 0.24 11.0 2.1 9 6.0 0.0 2.9 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal Elong_Iki1 PF10483.9 KEY73278.1 - 2.4e-100 335.9 0.0 2.7e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.12 KEY73278.1 - 0.0028 17.6 1.0 0.0041 17.0 0.5 1.6 1 1 0 1 1 1 1 NACHT domain ASXH PF13919.6 KEY73279.1 - 4.3e-35 120.8 0.0 6.5e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Asx homology domain FH2 PF02181.23 KEY73280.1 - 1.8e-84 284.0 6.1 1.8e-84 284.0 6.1 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KEY73280.1 - 2.5e-63 213.0 0.1 7.1e-63 211.6 0.1 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KEY73280.1 - 8e-54 182.2 1.8 3.4e-53 180.2 1.4 2.3 1 1 1 2 2 2 1 Diaphanous FH3 Domain Bap31_Bap29_C PF18035.1 KEY73280.1 - 0.075 13.0 11.5 0.018 15.1 4.6 3.2 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain SPC12 PF06645.13 KEY73281.1 - 0.15 12.1 0.5 0.23 11.5 0.5 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) VWA_CoxE PF05762.14 KEY73282.1 - 0.073 12.4 1.1 0.099 12.0 1.1 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Hus1 PF04005.12 KEY73283.1 - 2e-78 263.4 0.0 2.4e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 KEY73284.1 - 4.6e-108 361.4 0.0 6.7e-108 360.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KEY73284.1 - 3.5e-33 114.7 0.6 8.6e-33 113.4 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 KEY73284.1 - 0.064 12.4 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 Nuclear protein 96 PhoLip_ATPase_C PF16212.5 KEY73285.1 - 2.5e-51 174.8 4.1 2.5e-51 174.8 4.1 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEY73285.1 - 3e-17 62.1 0.5 6.3e-17 61.0 0.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEY73285.1 - 5e-14 53.1 0.1 1.1e-06 29.1 0.2 4.0 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEY73285.1 - 6.6e-06 25.8 0.0 0.0048 16.4 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KEY73285.1 - 3.3e-05 23.9 0.0 0.00063 19.8 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY73285.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.12 KEY73286.1 - 1.9e-60 204.1 0.0 2.6e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 KEY73286.1 - 2.5e-07 31.0 0.0 5.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEY73286.1 - 1.1e-05 26.0 0.1 0.00034 21.2 0.0 3.0 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEY73286.1 - 0.022 14.9 0.0 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aa_trans PF01490.18 KEY73287.1 - 1.7e-83 280.6 31.6 2e-83 280.4 31.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1056 PF06341.11 KEY73287.1 - 0.82 10.0 7.5 0.065 13.5 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) SPT_ssu-like PF11779.8 KEY73287.1 - 1.3 8.7 6.8 0.69 9.6 0.3 3.5 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like AA_permease PF00324.21 KEY73288.1 - 2.7e-61 207.7 29.0 3.3e-61 207.4 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KEY73288.1 - 6.6e-28 97.9 3.5 1.6e-10 40.6 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KEY73288.1 - 7e-21 74.5 33.2 1e-20 74.0 33.2 1.2 1 0 0 1 1 1 1 Amino acid permease cobW PF02492.19 KEY73289.1 - 1.9e-38 131.8 0.0 3.3e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KEY73289.1 - 0.00014 21.7 0.2 0.00036 20.4 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KEY73289.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF463 PF04317.12 KEY73289.1 - 0.015 14.2 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_22 PF13401.6 KEY73289.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEY73289.1 - 0.073 12.8 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KEY73289.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KEY73289.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 KEY73289.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KEY73289.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KEY73289.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase PUL PF08324.11 KEY73291.1 - 4.2e-62 209.9 0.0 5.7e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KEY73291.1 - 6.4e-35 120.2 0.0 9.8e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KEY73291.1 - 3.5e-13 49.4 0.0 7.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KEY73291.1 - 1.6e-06 28.1 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KEY73291.1 - 0.0011 19.4 0.1 0.0093 16.4 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KEY73291.1 - 0.023 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain PAD_N PF08526.10 KEY73291.1 - 0.04 14.3 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain DUF2847 PF11009.8 KEY73291.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) GDA1_CD39 PF01150.17 KEY73292.1 - 6e-105 351.3 0.0 8e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 KEY73293.1 - 7.4e-07 28.9 0.4 1.9e-06 27.6 0.4 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KEY73293.1 - 0.058 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KEY73294.1 - 3e-55 186.2 0.0 3.5e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY73294.1 - 6.3e-32 110.3 0.0 8.9e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY73294.1 - 1.2e-13 50.8 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEY73294.1 - 4.1e-08 33.3 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEY73294.1 - 4.2e-06 26.3 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEY73294.1 - 4.4e-05 23.1 0.0 0.0014 18.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY73294.1 - 0.0003 20.7 0.2 0.0038 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 KEY73294.1 - 0.0015 18.3 0.2 0.062 13.1 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KEY73294.1 - 0.0029 17.1 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KEY73294.1 - 0.0035 17.4 0.0 0.0062 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KEY73294.1 - 0.0055 16.4 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KEY73294.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY73294.1 - 0.0095 16.2 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KEY73294.1 - 0.02 14.2 0.2 0.048 12.9 0.0 1.7 3 0 0 3 3 3 0 Septin AAA_24 PF13479.6 KEY73294.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEY73294.1 - 0.022 14.3 0.0 0.08 12.5 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KEY73294.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KEY73294.1 - 0.069 13.0 0.2 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KEY73294.1 - 0.085 13.3 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KEY73294.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KEY73294.1 - 0.11 11.6 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 KEY73294.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KEY73294.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 KEY73294.1 - 0.13 11.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 KEY73294.1 - 0.23 10.6 1.1 1.5 7.9 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_21 PF13304.6 KEY73294.1 - 0.28 10.9 1.2 3.2 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Acyl-CoA_dh_1 PF00441.24 KEY73295.1 - 6.3e-29 101.1 0.4 1.1e-28 100.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEY73295.1 - 2.7e-20 72.4 0.0 4.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEY73295.1 - 1.4e-13 51.5 0.1 3.3e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEY73295.1 - 1.8e-12 47.7 0.2 4.7e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KEY73296.1 - 1e-15 57.3 1.8 1.9e-15 56.5 1.8 1.5 1 0 0 1 1 1 1 Spo12 family MMR_HSR1_Xtn PF16897.5 KEY73297.1 - 3.9e-37 126.5 1.6 8.3e-36 122.2 0.7 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KEY73297.1 - 5.3e-21 74.8 0.3 1.3e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KEY73297.1 - 7.3e-18 64.4 0.2 1.7e-17 63.2 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 KEY73297.1 - 1.7e-12 47.1 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEY73297.1 - 0.0003 20.9 3.4 0.025 14.6 0.0 2.6 2 1 1 3 3 3 2 Dynamin family MCM PF00493.23 KEY73297.1 - 0.075 12.1 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 KEY73297.1 - 0.082 11.9 0.1 0.18 10.7 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UreF PF01730.16 KEY73298.1 - 1.6e-23 83.8 0.1 2.7e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 UreF Pox_A_type_inc PF04508.12 KEY73298.1 - 0.023 14.5 0.1 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF429 PF04250.13 KEY73298.1 - 0.043 13.6 0.2 0.072 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Cut12 PF11500.8 KEY73299.1 - 3e-42 144.0 11.0 3e-42 144.0 11.0 4.2 3 2 2 5 5 5 1 Spindle pole body formation-associated protein Tup_N PF08581.10 KEY73299.1 - 0.012 15.9 13.6 3.9 7.8 0.4 3.8 3 0 0 3 3 3 0 Tup N-terminal DUF4263 PF14082.6 KEY73299.1 - 0.081 13.2 5.2 0.13 12.5 1.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) HGTP_anticodon2 PF12745.7 KEY73300.1 - 2.1e-80 270.1 2.3 2.1e-80 270.1 2.3 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KEY73300.1 - 4.1e-74 249.3 0.0 2.5e-35 122.2 0.0 3.8 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73300.1 - 1.5e-45 155.5 0.0 4.4e-19 68.8 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KEY73300.1 - 1.5e-18 67.1 0.0 1.5e-18 67.1 0.0 2.9 4 0 0 4 4 4 1 Histidyl-tRNA synthetase RWD PF05773.22 KEY73300.1 - 4.5e-12 46.3 0.0 1.6e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KEY73300.1 - 0.00024 21.1 2.4 0.53 10.2 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family TIP120 PF08623.10 KEY73300.1 - 0.016 15.0 0.7 0.042 13.6 0.7 1.7 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Pox_ser-thr_kin PF05445.11 KEY73300.1 - 0.094 11.7 0.3 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 KEY73300.1 - 1.6 8.2 7.0 1.5 8.3 0.0 3.5 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL UQ_con PF00179.26 KEY73301.1 - 2e-33 115.0 0.0 2.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme YL1 PF05764.13 KEY73301.1 - 0.2 11.8 13.0 0.27 11.3 13.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Sporozoite_P67 PF05642.11 KEY73301.1 - 0.68 7.9 6.0 0.83 7.7 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UIM PF02809.20 KEY73302.1 - 1.8 8.7 9.0 2.6 8.2 7.5 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif DnaJ_C PF01556.18 KEY73303.1 - 6.2e-39 133.4 1.2 8.4e-39 133.0 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEY73303.1 - 2.9e-26 91.4 3.4 5.2e-26 90.5 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain HAD_2 PF13419.6 KEY73304.1 - 1.1e-25 90.7 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEY73304.1 - 3e-11 44.0 0.4 8.7e-11 42.5 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KEY73304.1 - 2.5e-08 33.8 0.0 1.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 KEY73304.1 - 5.7e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAS-barrel PF09378.10 KEY73304.1 - 0.0056 16.8 0.1 0.77 10.0 0.0 2.3 2 0 0 2 2 2 1 HAS barrel domain Hydrolase_6 PF13344.6 KEY73304.1 - 0.014 15.5 0.0 0.81 9.8 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY73304.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 KEY73305.1 - 1.4e-99 333.0 0.0 2e-99 332.4 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KEY73305.1 - 2.5e-31 108.2 0.0 4.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain GFO_IDH_MocA PF01408.22 KEY73305.1 - 9e-10 39.4 0.2 3.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KEY73305.1 - 0.06 13.8 0.0 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain MFS_1 PF07690.16 KEY73306.1 - 9.2e-39 133.3 45.6 9.2e-39 133.3 45.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DHDPS PF00701.22 KEY73306.1 - 6.2e-33 113.7 0.0 1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sugar_tr PF00083.24 KEY73306.1 - 4.6e-19 68.6 4.3 4.6e-19 68.6 4.3 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEY73306.1 - 0.00015 20.3 15.9 0.00017 20.2 14.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MARVEL PF01284.23 KEY73307.1 - 0.00063 19.8 11.3 0.001 19.1 11.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 KEY73307.1 - 0.00064 20.1 1.3 0.0011 19.3 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DUF2070 PF09843.9 KEY73307.1 - 0.024 13.0 3.5 0.031 12.6 3.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Serglycin PF04360.12 KEY73307.1 - 0.33 10.9 2.0 0.49 10.3 2.0 1.2 1 0 0 1 1 1 0 Serglycin Nop16 PF09420.10 KEY73308.1 - 3e-76 256.1 7.5 8.9e-64 215.4 2.4 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Nsp1_C PF05064.13 KEY73308.1 - 0.039 13.7 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region Sdh5 PF03937.16 KEY73308.1 - 0.081 12.9 0.4 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase FANC_SAP PF18081.1 KEY73308.1 - 2.3 8.4 7.3 0.69 10.1 0.7 3.0 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain DAO PF01266.24 KEY73309.1 - 1.6e-64 218.7 0.9 1.9e-64 218.5 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY73309.1 - 0.00086 19.5 0.2 0.002 18.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY73309.1 - 0.0042 17.6 0.2 1.6 9.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY73309.1 - 0.005 16.1 0.9 0.97 8.6 0.2 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KEY73309.1 - 0.019 14.4 0.1 1 8.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Mqo PF06039.15 KEY73309.1 - 0.029 12.9 0.2 0.41 9.2 0.1 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 KEY73309.1 - 0.09 12.0 0.3 0.16 11.2 0.3 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MCRA PF06100.11 KEY73309.1 - 0.14 10.9 3.2 2.8 6.6 0.2 2.1 2 0 0 2 2 2 0 MCRA family Prenylcys_lyase PF07156.14 KEY73309.1 - 0.18 10.9 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase GSHPx PF00255.19 KEY73310.1 - 1.5e-40 137.1 0.2 1.9e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KEY73310.1 - 0.00031 20.7 0.1 0.00049 20.0 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEY73310.1 - 0.00048 19.8 0.1 0.00079 19.2 0.1 1.4 1 0 0 1 1 1 1 Redoxin Fungal_trans_2 PF11951.8 KEY73312.1 - 1.6e-47 162.1 7.5 1.3e-46 159.2 7.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73312.1 - 4.5e-07 29.9 7.3 1e-06 28.7 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase_4 PF13230.6 KEY73314.1 - 1.8e-15 56.6 0.1 1e-12 47.6 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KEY73314.1 - 8e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.32 KEY73315.1 - 1.3e-07 32.1 8.8 11 7.0 0.0 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY73315.1 - 0.00026 21.2 0.1 0.036 14.4 0.0 4.1 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 KEY73315.1 - 0.042 13.8 0.0 8.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Heme_oxygenase PF01126.20 KEY73316.1 - 1.1e-09 38.3 0.0 1e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase TFIIF_alpha PF05793.12 KEY73316.1 - 4.4 5.8 4.5 7.7 5.0 4.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3955 PF13127.6 KEY73317.1 - 5.3e-11 42.2 2.7 1.4e-10 40.8 0.4 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) EamA PF00892.20 KEY73317.1 - 5.8e-11 42.7 33.0 6.8e-07 29.5 1.9 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KEY73317.1 - 8.9e-05 22.1 10.7 8.9e-05 22.1 10.7 1.6 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 KEY73317.1 - 0.00018 20.8 1.3 0.00018 20.8 1.3 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KEY73317.1 - 0.0046 16.3 8.0 0.014 14.8 0.3 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KEY73317.1 - 0.031 13.5 13.7 0.011 14.9 10.9 1.6 2 0 0 2 2 2 0 UAA transporter family SR-25 PF10500.9 KEY73317.1 - 4.4 6.8 8.4 6.4 6.3 8.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NMT1 PF09084.11 KEY73318.1 - 0.00069 19.6 0.0 0.0032 17.4 0.0 1.9 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KEY73318.1 - 0.0031 17.0 0.0 0.027 13.9 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.6 KEY73318.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein MFS_1 PF07690.16 KEY73320.1 - 9.3e-33 113.6 55.9 1.1e-29 103.5 35.3 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 KEY73320.1 - 0.0038 15.7 11.7 0.018 13.5 11.9 1.9 1 1 1 2 2 2 1 Transmembrane secretion effector CitMHS PF03600.16 KEY73320.1 - 3.2 6.9 23.9 0.49 9.5 18.8 2.0 1 1 1 2 2 2 0 Citrate transporter OATP PF03137.20 KEY73320.1 - 5.7 5.1 9.8 0.39 9.0 2.1 2.6 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CAF1A PF12253.8 KEY73322.1 - 2.4e-24 85.3 2.3 2.4e-24 85.3 2.3 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Hamartin PF04388.12 KEY73322.1 - 0.021 13.5 16.1 0.032 12.9 16.1 1.3 1 0 0 1 1 1 0 Hamartin protein Borrelia_P83 PF05262.11 KEY73322.1 - 2 6.8 27.7 2.8 6.3 27.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MCM3AP_GANP PF16769.5 KEY73322.1 - 9.4 4.3 13.9 13 3.8 13.9 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP EXS PF03124.14 KEY73324.1 - 7.5e-94 314.7 23.2 9.2e-94 314.4 23.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KEY73324.1 - 2e-77 261.7 1.1 2e-77 261.7 1.1 2.0 2 0 0 2 2 2 1 SPX domain FUR PF01475.19 KEY73324.1 - 0.12 12.5 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family Peptidase_M18 PF02127.15 KEY73325.1 - 1.1e-129 433.0 0.0 1.3e-129 432.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) 2-Hacid_dh_C PF02826.19 KEY73329.1 - 7.7e-51 172.0 0.0 1.6e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY73329.1 - 1e-15 57.6 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AA_permease_2 PF13520.6 KEY73330.1 - 1.8e-61 208.3 42.0 2.3e-61 207.9 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY73330.1 - 5e-28 97.9 26.1 5e-28 97.9 26.1 2.1 2 0 0 2 2 2 1 Amino acid permease DUF1754 PF08555.10 KEY73331.1 - 2.1e-13 50.9 9.0 2.9e-13 50.4 9.0 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SOG2 PF10428.9 KEY73333.1 - 1.5 8.0 18.4 2.1 7.5 18.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Totivirus_coat PF05518.11 KEY73333.1 - 3.1 5.7 13.9 4.6 5.2 13.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein ORC2 PF04084.14 KEY73335.1 - 2.1e-118 395.1 0.0 2.5e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PGP_phosphatase PF09419.10 KEY73336.1 - 4.5e-65 218.3 0.0 5.2e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KEY73336.1 - 8.1e-05 22.6 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEY73336.1 - 0.0022 18.3 0.0 0.0029 17.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase STAC2_u1 PF16664.5 KEY73337.1 - 3.5 8.1 6.4 1.7 9.1 3.0 2.0 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Tim17 PF02466.19 KEY73338.1 - 1.4e-38 131.7 8.7 1.9e-38 131.2 8.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KEY73338.1 - 0.021 14.8 0.4 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glyco_hydro_16 PF00722.21 KEY73339.1 - 5.3e-09 35.8 0.0 8.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box PF00646.33 KEY73340.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KEY73340.1 - 0.045 13.6 0.5 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 KEY73340.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 F-box DUF1660 PF07874.11 KEY73340.1 - 0.24 11.9 1.6 0.45 11.0 1.6 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) GDH_N PF12466.8 KEY73341.1 - 0.092 13.0 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal APH PF01636.23 KEY73342.1 - 1.6e-16 61.0 0.3 2.2e-16 60.5 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KEY73342.1 - 0.00057 19.3 0.0 0.002 17.5 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73342.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KEY73342.1 - 0.016 14.8 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KEY73342.1 - 0.17 11.4 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family fn3_3 PF14686.6 KEY73344.1 - 1.1e-23 82.8 0.1 2.7e-23 81.5 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KEY73344.1 - 5e-23 81.8 0.0 8.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III DUF2220 PF09983.9 KEY73344.1 - 0.022 14.1 0.1 0.054 12.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) SKIP_SNW PF02731.15 KEY73345.1 - 2.1e-67 225.8 7.7 2.1e-67 225.8 7.7 2.8 3 0 0 3 3 3 1 SKIP/SNW domain EMP24_GP25L PF01105.24 KEY73346.1 - 3.2e-48 164.1 2.6 3.6e-48 163.9 2.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_C36 PF05415.11 KEY73346.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase PhoD PF09423.10 KEY73347.1 - 5.5e-35 121.0 0.1 1.1e-34 120.1 0.1 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase Rrp15p PF07890.12 KEY73348.1 - 2.3e-36 125.1 11.1 2.3e-36 125.1 11.1 2.6 2 1 0 2 2 2 1 Rrp15p DUF4611 PF15387.6 KEY73348.1 - 1.2 9.4 16.3 0.087 13.1 8.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Fer2 PF00111.27 KEY73349.1 - 4.1e-13 49.1 2.0 5.5e-13 48.7 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KEY73350.1 - 6.6e-14 51.6 4.5 0.00032 20.6 0.0 5.1 4 2 0 4 4 4 3 Mitochondrial carrier protein COMPASS-Shg1 PF05205.12 KEY73351.1 - 1.9e-24 86.3 0.3 1.9e-24 86.3 0.3 2.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 TPT PF03151.16 KEY73352.1 - 3.4e-25 89.0 21.9 4.2e-25 88.7 21.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEY73352.1 - 0.0052 17.0 40.0 0.047 13.9 13.7 2.5 3 0 0 3 3 3 2 EamA-like transporter family UCH PF00443.29 KEY73353.1 - 1.3e-34 119.9 0.0 2.1e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEY73353.1 - 4.3e-09 36.4 0.0 7.9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2079 PF09852.9 KEY73353.1 - 0.016 14.1 0.1 0.024 13.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) SP2 PF03014.14 KEY73353.1 - 0.13 10.7 0.1 0.18 10.1 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 TauD PF02668.16 KEY73354.1 - 6.2e-36 124.6 0.0 8.5e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KEY73354.1 - 0.063 13.9 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) CsiD PF08943.10 KEY73354.1 - 0.078 12.1 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 CsiD adh_short_C2 PF13561.6 KEY73355.1 - 2.3e-55 187.7 4.4 6.2e-55 186.3 4.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY73355.1 - 4.1e-33 114.5 4.4 2.7e-32 111.8 4.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY73355.1 - 9.2e-08 32.2 1.2 3e-07 30.5 1.2 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEY73355.1 - 0.0084 16.0 1.2 0.0092 15.9 0.3 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEY73355.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3335 PF11814.8 KEY73355.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family DUF2190 PF09956.9 KEY73355.1 - 1.4 9.4 5.0 2.8 8.5 1.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) Metallophos PF00149.28 KEY73356.1 - 9.4e-38 130.8 0.1 1.8e-37 129.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAC3 PF10178.9 KEY73357.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 KEY73358.1 - 1.8e-22 79.7 0.0 1.8e-22 79.7 0.0 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEY73358.1 - 2.7e-13 50.1 0.0 5.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEY73358.1 - 6.8e-12 45.7 0.1 2.6e-11 43.9 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY73358.1 - 2.4e-08 34.0 0.2 2.7e-07 30.5 0.0 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEY73358.1 - 0.00011 22.5 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY73358.1 - 0.00039 20.2 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY73358.1 - 0.00052 20.4 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEY73358.1 - 0.0076 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KEY73358.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 KEY73358.1 - 0.019 15.5 9.2 0.062 13.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KEY73358.1 - 0.14 11.5 1.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 KaiC Med6 PF04934.14 KEY73359.1 - 5.7e-38 129.7 0.0 9e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.9 KEY73360.1 - 8.2e-32 109.3 1.8 1.3e-31 108.6 1.8 1.4 1 0 0 1 1 1 1 Multiple myeloma tumor-associated DUF3684 PF12449.8 KEY73361.1 - 0 1497.6 0.0 0 1497.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KEY73361.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 KEY73361.1 - 0.03 14.5 0.1 0.073 13.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 IF-2B PF01008.17 KEY73363.1 - 2.1e-46 158.4 0.1 5.2e-46 157.1 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF562 PF04763.12 KEY73363.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF562) Ndc1_Nup PF09531.10 KEY73363.1 - 0.65 8.6 7.6 0.86 8.2 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArgJ PF01960.18 KEY73364.1 - 3.5e-150 499.9 0.0 3.9e-150 499.7 0.0 1.0 1 0 0 1 1 1 1 ArgJ family IGPD PF00475.18 KEY73365.1 - 8.3e-59 198.0 0.1 1.1e-58 197.7 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TPR_2 PF07719.17 KEY73366.1 - 3.9e-25 85.9 17.4 0.0074 16.3 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY73366.1 - 1.2e-24 86.4 1.3 1.2e-24 86.4 1.3 5.3 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KEY73366.1 - 2.8e-22 77.6 13.1 0.00094 18.9 0.2 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73366.1 - 9.9e-21 74.0 21.7 0.00031 21.2 0.1 7.6 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73366.1 - 2.9e-18 64.5 8.1 0.025 14.8 0.1 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73366.1 - 1.9e-15 56.9 23.2 3e-07 30.6 0.1 9.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73366.1 - 5e-13 48.7 23.6 0.16 12.9 0.0 10.0 5 4 5 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73366.1 - 1.2e-11 45.0 19.4 0.0012 19.4 0.1 8.3 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEY73366.1 - 2.9e-10 39.7 6.3 0.0076 15.9 0.0 7.8 7 1 1 8 8 8 3 TPR repeat TPR_10 PF13374.6 KEY73366.1 - 1.3e-07 31.2 9.2 0.16 11.9 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73366.1 - 1.1e-06 28.2 14.7 12 6.2 0.0 8.8 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY73366.1 - 3.5e-06 27.3 11.4 15 6.5 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEY73366.1 - 4e-05 23.7 2.8 1.1 9.4 0.1 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KEY73366.1 - 0.0054 16.8 1.0 1.7 8.8 0.0 4.1 4 1 0 4 4 4 1 Rapsyn N-terminal myristoylation and linker region HrpB1_HrpK PF09613.10 KEY73366.1 - 0.083 12.5 0.4 10 5.8 0.1 3.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KEY73366.1 - 0.1 13.3 11.4 0.96 10.3 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat AMP-binding PF00501.28 KEY73369.1 - 1.3e-40 139.3 0.0 1.9e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEY73369.1 - 1.8e-07 31.0 0.2 4.8e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KEY73369.1 - 0.00078 20.4 0.1 0.0018 19.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAT PF02259.23 KEY73370.1 - 4.5e-72 243.1 7.5 1.1e-71 241.9 7.5 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KEY73370.1 - 1.5e-31 110.1 0.2 4.2e-31 108.7 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KEY73370.1 - 3.9e-06 26.6 0.1 1.2e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain AAA_32 PF13654.6 KEY73370.1 - 0.053 12.3 0.2 0.22 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KEY73370.1 - 0.33 11.2 2.0 2.1 8.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ric8 PF10165.9 KEY73370.1 - 7.4 5.5 10.5 12 4.7 0.0 4.6 5 0 0 5 5 5 0 Guanine nucleotide exchange factor synembryn GGACT PF06094.12 KEY73371.1 - 6.3e-21 75.2 0.1 8.7e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_61 PF03443.14 KEY73372.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KEY73372.1 - 9.6e-05 23.1 0.0 0.00036 21.3 0.0 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SMI1_KNR4 PF09346.10 KEY73373.1 - 4.4e-33 114.5 0.0 7.9e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.14 KEY73374.1 - 1.9e-48 163.9 1.0 1.9e-48 163.9 1.0 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KEY73374.1 - 6.7e-11 42.0 1.0 1.2e-10 41.2 1.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Swi5 PF07061.11 KEY73374.1 - 0.024 14.7 0.3 0.077 13.1 0.3 1.8 1 0 0 1 1 1 0 Swi5 YcbB PF08664.10 KEY73374.1 - 0.031 14.3 0.2 0.067 13.2 0.2 1.5 1 0 0 1 1 1 0 YcbB domain Phage_GP20 PF06810.11 KEY73374.1 - 0.13 12.0 0.3 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 Lebercilin PF15619.6 KEY73374.1 - 0.17 11.6 4.4 0.39 10.4 2.6 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 KEY73374.1 - 1.7 8.1 4.7 4.9 6.6 4.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit EHN PF06441.12 KEY73375.1 - 3.7e-27 94.8 0.2 7.2e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.7 KEY73376.1 - 1.9e-296 985.6 0.0 2.2e-296 985.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KEY73376.1 - 1e-100 338.0 0.0 1.3e-100 337.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 KEY73376.1 - 0.034 13.1 0.1 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Stm1_N PF09598.10 KEY73376.1 - 0.99 10.3 4.1 2.6 8.9 4.1 1.7 1 0 0 1 1 1 0 Stm1 Pet127 PF08634.10 KEY73377.1 - 6.7e-112 373.4 0.8 1.1e-111 372.7 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Metallophos PF00149.28 KEY73378.1 - 9.5e-12 45.8 0.1 1.4e-11 45.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3431 PF11913.8 KEY73378.1 - 0.0037 17.1 0.1 0.0083 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DDE_Tnp_1_7 PF13843.6 KEY73379.1 - 3.8e-05 23.2 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 IL4_i_Ig PF18258.1 KEY73379.1 - 0.014 15.6 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain ATP-synt_ab PF00006.25 KEY73380.1 - 1.5e-109 364.7 0.0 2.2e-109 364.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KEY73380.1 - 2.5e-46 156.5 0.0 5.7e-46 155.3 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KEY73380.1 - 0.001 19.6 4.9 0.0012 19.3 1.7 2.5 2 1 1 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain F_actin_bind PF08919.10 KEY73380.1 - 0.061 13.4 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 F-actin binding UPF0029 PF01205.19 KEY73381.1 - 2.9e-34 117.5 0.0 5.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KEY73381.1 - 0.0029 17.9 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 RWD domain ACT_7 PF13840.6 KEY73382.1 - 1.2e-16 60.2 0.2 1e-10 41.3 0.2 2.4 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.6 KEY73383.1 - 2.7e-24 86.0 0.0 4.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Clavanin PF05452.11 KEY73383.1 - 0.097 12.9 0.3 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 Clavanin VHL_C PF17211.3 KEY73383.1 - 0.17 12.0 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 VHL box domain Syntaxin-6_N PF09177.11 KEY73384.1 - 1.1e-21 77.2 0.0 7e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KEY73384.1 - 0.00012 22.0 0.9 0.00029 20.7 0.9 1.7 1 0 0 1 1 1 1 SNARE domain UPF0242 PF06785.11 KEY73384.1 - 0.013 15.7 0.1 4.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3348 PF11828.8 KEY73384.1 - 0.018 14.8 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Use1 PF09753.9 KEY73384.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 1 1 2 2 2 0 Membrane fusion protein Use1 TBCA PF02970.16 KEY73384.1 - 0.49 10.8 4.7 0.39 11.1 1.6 2.3 3 1 0 3 3 3 0 Tubulin binding cofactor A CENP-F_leu_zip PF10473.9 KEY73384.1 - 0.72 9.9 4.9 2 8.5 1.3 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KEY73384.1 - 9.3 6.4 7.9 3.6 7.8 2.8 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) GLE1 PF07817.13 KEY73385.1 - 2.9e-62 210.1 0.0 3.9e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein SLATT_1 PF18181.1 KEY73385.1 - 0.094 12.7 0.4 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 CENP-Q PF13094.6 KEY73385.1 - 0.19 12.0 13.8 0.52 10.5 13.7 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3287 PF11690.8 KEY73385.1 - 0.25 11.1 2.2 0.66 9.7 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) RNB PF00773.19 KEY73386.1 - 2.3e-81 273.6 0.0 4.1e-81 272.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KEY73386.1 - 1.1e-25 89.4 0.0 2.4e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KEY73386.1 - 4e-25 87.9 0.0 1.4e-24 86.2 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KEY73386.1 - 1e-05 25.6 0.0 0.017 15.3 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KEY73386.1 - 0.048 13.4 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Rrp44-like cold shock domain NPR3 PF03666.13 KEY73386.1 - 6.4 5.4 9.4 0.25 10.1 1.1 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ferritin_2 PF13668.6 KEY73388.1 - 4.8e-36 124.0 0.5 7.7e-36 123.3 0.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain MKT1_C PF12246.8 KEY73389.1 - 6.3e-69 231.9 0.0 8.9e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KEY73389.1 - 9e-31 106.1 0.0 1.9e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KEY73389.1 - 0.0013 19.2 0.0 0.0087 16.5 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain DNA_ligase_A_M PF01068.21 KEY73390.1 - 3.6e-22 79.0 0.0 6.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEY73390.1 - 7e-20 72.1 0.0 1.5e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KEY73390.1 - 3.1e-06 27.6 0.0 7.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RNA ligase DIOX_N PF14226.6 KEY73391.1 - 4.6e-23 82.2 0.0 7.4e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY73391.1 - 2.1e-14 53.8 0.0 4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4048 PF13257.6 KEY73392.1 - 2.2e-08 34.3 11.7 9.9e-07 28.9 0.3 3.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) CTD_bind PF04818.13 KEY73392.1 - 0.059 14.2 0.0 0.34 11.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF4188 PF13826.6 KEY73393.1 - 4.1e-29 101.3 0.1 5.5e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KEY73393.1 - 3.1e-05 23.5 0.1 5.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Haem-containing dehydratase Glyco_hydro_76 PF03663.14 KEY73395.1 - 7.2e-153 509.4 7.2 8.3e-153 509.2 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY73395.1 - 0.0031 16.7 10.4 0.059 12.4 0.2 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Dak1 PF02733.17 KEY73396.1 - 5.8e-108 360.5 6.7 5.8e-108 360.5 6.7 1.6 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KEY73396.1 - 5.4e-46 156.7 0.0 1.1e-45 155.7 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KEY73397.1 - 5.1e-18 64.5 0.2 7e-18 64.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain ECH_2 PF16113.5 KEY73398.1 - 5.6e-123 410.7 0.0 8.2e-123 410.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEY73398.1 - 2e-25 89.6 0.0 3e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase CLP1_N PF16573.5 KEY73398.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor GATA PF00320.27 KEY73399.1 - 0.01 15.5 8.3 0.028 14.0 1.5 2.7 2 0 0 2 2 2 2 GATA zinc finger NMO PF03060.15 KEY73400.1 - 1.4e-56 192.3 0.7 3.1e-55 187.9 0.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEY73400.1 - 3.9e-12 45.8 0.7 8.8e-10 38.1 0.7 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY73400.1 - 0.001 18.2 0.2 0.0019 17.3 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KEY73400.1 - 0.093 11.9 0.1 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.12 KEY73400.1 - 0.15 11.2 0.1 0.56 9.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF561) F-box-like PF12937.7 KEY73401.1 - 0.011 15.6 0.2 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like DUF3396 PF11876.8 KEY73401.1 - 0.056 12.9 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) p450 PF00067.22 KEY73402.1 - 3.5e-38 131.6 0.0 6.8e-37 127.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Med13_C PF06333.12 KEY73403.1 - 6.3e-87 291.9 5.2 6.3e-87 291.9 5.2 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KEY73403.1 - 1.3e-28 100.3 2.2 1.3e-28 100.3 2.2 2.2 3 0 0 3 3 3 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KEY73403.1 - 7.8e-10 39.0 0.1 2.1e-07 31.0 0.2 2.6 1 1 0 2 2 2 2 MID domain of medPIWI Clr5 PF14420.6 KEY73404.1 - 1.4e-17 63.6 0.3 2.5e-17 62.8 0.3 1.4 1 0 0 1 1 1 1 Clr5 domain Exo_endo_phos_2 PF14529.6 KEY73405.1 - 1.3e-05 25.0 0.2 5e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF89 PF01937.19 KEY73405.1 - 0.045 12.7 1.2 0.056 12.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Thioredoxin_8 PF13905.6 KEY73405.1 - 0.062 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF241 PF03087.14 KEY73405.1 - 0.2 11.5 1.9 0.29 10.9 1.1 1.7 2 0 0 2 2 2 0 Arabidopsis protein of unknown function HeLo PF14479.6 KEY73405.1 - 0.24 11.2 6.6 0.35 10.7 2.4 2.2 2 1 0 2 2 2 0 Prion-inhibition and propagation Lactonase PF10282.9 KEY73407.1 - 1.8e-10 40.6 0.0 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DDE_1 PF03184.19 KEY73410.1 - 3.7e-34 117.9 0.1 6.2e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 KEY73410.1 - 4.3e-09 36.0 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_1 PF00126.27 KEY73410.1 - 0.0042 17.0 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 KEY73410.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.13 KEY73410.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain FAD-SLDH PF12318.8 KEY73410.1 - 0.12 12.5 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DDE_3 PF13358.6 KEY73410.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease Glyco_hydro_18 PF00704.28 KEY73411.1 - 2.1e-67 228.1 0.9 2.5e-67 227.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TehB PF03848.14 KEY73411.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CAP59_mtransfer PF11735.8 KEY73412.1 - 7.7e-60 202.6 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 GGACT PF06094.12 KEY73412.1 - 0.095 13.3 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like HET PF06985.11 KEY73413.1 - 2e-34 119.1 0.5 2.9e-34 118.5 0.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.28 KEY73414.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KEY73415.1 - 6.7e-26 91.8 0.0 8.7e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.7 KEY73417.1 - 3.3e-15 56.4 5.9 0.0041 17.7 0.0 6.5 3 3 2 6 6 6 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 KEY73417.1 - 1.5e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KEY73417.1 - 3.2e-11 42.4 2.1 0.026 15.0 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KEY73417.1 - 5.3e-11 42.8 1.0 0.1 13.2 0.0 6.0 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KEY73417.1 - 1.7e-10 40.9 3.8 0.12 12.9 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KEY73417.1 - 5.3e-08 33.0 0.2 0.22 11.9 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) HeLo PF14479.6 KEY73418.1 - 0.082 12.7 1.7 1.4 8.7 1.7 2.4 1 1 0 1 1 1 0 Prion-inhibition and propagation RibD_C PF01872.17 KEY73419.1 - 2.6e-17 63.3 0.0 1.6e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 KEY73419.1 - 7.6e-06 25.7 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Zn_clus PF00172.18 KEY73420.1 - 1.9e-08 34.3 12.2 3.4e-08 33.5 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY73420.1 - 9.1e-05 21.6 0.3 0.00048 19.2 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain La_HTH_kDCL PF18177.1 KEY73420.1 - 0.019 15.3 0.0 0.61 10.4 0.0 2.6 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain IL34 PF15036.6 KEY73420.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin 34 FANCI_S1-cap PF14674.6 KEY73420.1 - 0.092 12.8 1.3 4.1 7.6 0.4 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap FAD_binding_3 PF01494.19 KEY73421.1 - 1.5e-18 67.2 0.0 1.1e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY73421.1 - 1.7e-08 34.4 0.1 0.00062 19.4 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY73421.1 - 3.6e-08 33.0 0.0 6.1e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY73421.1 - 7.2e-06 26.5 0.1 4.4e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEY73421.1 - 0.028 14.0 0.0 0.46 10.1 0.0 2.2 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KEY73421.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY73421.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TPR_12 PF13424.6 KEY73422.1 - 1e-15 57.7 11.5 0.00026 21.2 0.4 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEY73422.1 - 1.4e-11 43.9 10.6 4.6e-05 23.1 0.1 5.3 5 0 0 5 5 4 4 Tetratricopeptide repeat NACHT PF05729.12 KEY73422.1 - 4.5e-07 29.9 0.0 1.6e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.28 KEY73422.1 - 0.00085 19.0 2.8 0.0054 16.5 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KEY73422.1 - 0.0016 19.1 1.0 0.008 16.8 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KEY73422.1 - 0.0017 18.8 0.5 0.025 15.0 0.1 2.9 2 1 0 2 2 1 1 AAA ATPase domain TPR_2 PF07719.17 KEY73422.1 - 0.002 18.1 3.9 0.094 12.9 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Cutinase PF01083.22 KEY73422.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Cutinase NB-ARC PF00931.22 KEY73422.1 - 0.0025 17.0 0.0 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain PGAP1 PF07819.13 KEY73422.1 - 0.006 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 KEY73422.1 - 0.011 16.0 0.1 0.099 12.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KEY73422.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KEY73422.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KEY73422.1 - 0.029 14.0 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KEY73422.1 - 0.031 13.6 0.0 0.085 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC TPR_7 PF13176.6 KEY73422.1 - 0.032 14.2 0.1 0.19 11.8 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ResIII PF04851.15 KEY73422.1 - 0.035 14.1 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPR_8 PF13181.6 KEY73422.1 - 0.078 13.2 0.1 0.65 10.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF676 PF05057.14 KEY73422.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_16 PF13432.6 KEY73422.1 - 0.13 12.9 8.7 14 6.5 0.1 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73422.1 - 6.4 7.9 7.0 17 6.6 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2628 PF10947.8 KEY73423.1 - 4.7 7.6 6.8 7.8 6.9 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Ank_2 PF12796.7 KEY73424.1 - 5.8e-24 84.5 16.9 5.3e-09 36.5 0.0 9.5 4 3 5 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73424.1 - 6.4e-12 45.8 7.9 0.00056 20.4 0.0 9.3 7 3 1 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73424.1 - 4.8e-11 41.9 9.9 0.24 12.1 0.0 12.6 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.6 KEY73424.1 - 0.0025 18.1 15.7 0.01 16.2 0.0 6.8 8 1 1 9 9 9 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY73424.1 - 0.032 14.7 23.2 0.21 12.1 0.1 10.2 13 0 0 13 13 13 0 Ankyrin repeat Fungal_trans_2 PF11951.8 KEY73426.1 - 0.1 11.4 8.5 0.29 9.9 4.6 2.7 2 1 0 2 2 2 0 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KEY73427.1 - 6.3e-74 248.8 0.0 7.2e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_61 PF03443.14 KEY73428.1 - 8.3e-45 153.2 0.0 1.1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 KEY73429.1 - 6e-68 229.7 0.0 6.7e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_assoc_2 PF16193.5 KEY73429.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain MFS_1 PF07690.16 KEY73430.1 - 3.2e-36 125.0 22.6 3.2e-36 125.0 22.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KEY73430.1 - 0.74 8.0 8.0 0.015 13.6 0.9 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 KEY73431.1 - 5e-21 74.9 0.0 8.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73431.1 - 1e-06 28.7 10.8 1.8e-06 28.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KEY73432.1 - 9e-207 687.5 0.8 1.2e-206 687.2 0.8 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEY73432.1 - 1.4e-88 297.0 0.0 3.1e-88 295.8 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEY73432.1 - 2.4e-57 193.5 0.1 8.6e-56 188.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RTA1 PF04479.13 KEY73433.1 - 1.2e-45 155.6 2.3 1.8e-45 155.1 2.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Pec_lyase_C PF00544.19 KEY73435.1 - 1.3e-35 122.9 6.4 1.7e-35 122.6 6.4 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KEY73435.1 - 0.0014 18.5 11.6 0.17 11.7 11.7 2.7 1 1 0 1 1 1 1 Right handed beta helix region COesterase PF00135.28 KEY73436.1 - 7.8e-85 285.7 0.0 9e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY73436.1 - 0.00022 21.1 0.1 0.00098 19.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold KdpD PF02702.17 KEY73437.1 - 0.26 10.7 0.0 0.38 10.2 0.0 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Ubiquitin_2 PF14560.6 KEY73438.1 - 0.094 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Zn_clus PF00172.18 KEY73439.1 - 1.3e-09 38.0 9.5 2.1e-09 37.3 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY73439.1 - 4.7e-05 22.6 0.1 8.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEY73440.1 - 1.4e-89 301.0 19.9 1.8e-89 300.7 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73440.1 - 2.9e-23 82.4 54.8 2e-12 46.7 5.4 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KEY73440.1 - 0.99 8.2 17.0 0.031 13.1 5.2 2.3 2 0 0 2 2 2 0 MFS_1 like family Alpha-amylase PF00128.24 KEY73441.1 - 7.9e-111 370.9 0.0 1.3e-110 370.2 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KEY73441.1 - 0.0001 21.6 0.1 0.0002 20.6 0.1 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KEY73441.1 - 0.00052 20.1 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain COX_ARM PF06481.14 KEY73441.1 - 0.023 14.6 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 COX Aromatic Rich Motif Catalase PF00199.19 KEY73442.1 - 5.5e-65 219.9 0.0 6.1e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase PF00199.19 KEY73443.1 - 7e-27 94.5 0.3 1.2e-26 93.8 0.3 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KEY73443.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase PF00199.19 KEY73444.1 - 3.8e-152 506.8 0.1 4.8e-152 506.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KEY73444.1 - 5.2e-15 55.4 0.1 9.9e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_S8 PF00082.22 KEY73445.1 - 2.3e-21 76.4 17.4 6.7e-21 74.8 17.4 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY73445.1 - 5.6e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 GMC_oxred_N PF00732.19 KEY73446.1 - 1.5e-57 195.2 0.0 2e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73446.1 - 6.9e-24 85.0 0.0 1.7e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY73446.1 - 1.2e-06 27.8 0.2 0.036 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEY73446.1 - 2.5e-06 26.8 0.1 4.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY73446.1 - 0.00011 22.0 0.1 0.00028 20.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY73446.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY73446.1 - 0.00022 20.5 0.1 0.00049 19.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KEY73446.1 - 0.0025 16.7 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KEY73446.1 - 0.014 14.6 1.6 0.83 8.8 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.27 KEY73446.1 - 0.017 15.7 0.0 0.086 13.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY73446.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEY73446.1 - 0.035 13.4 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KEY73446.1 - 0.12 10.8 0.0 0.34 9.4 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 KEY73446.1 - 0.94 8.8 2.6 1.7 7.9 0.4 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase CorA PF01544.18 KEY73447.1 - 3.8e-08 33.0 0.3 4.8e-08 32.7 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 KEY73447.1 - 0.012 15.6 1.4 0.027 14.5 1.3 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 KEY73447.1 - 0.06 13.5 0.1 0.06 13.5 0.1 2.3 2 1 1 3 3 3 0 HemY protein N-terminus F-box_4 PF15966.5 KEY73448.1 - 0.14 12.1 0.2 0.36 10.7 0.2 1.7 1 1 0 1 1 1 0 F-box An_peroxidase PF03098.15 KEY73451.1 - 2.3e-41 142.0 0.0 3.3e-29 101.9 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KEY73451.1 - 3.1e-08 32.8 0.0 7.6e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Octopine_DH PF02317.17 KEY73452.1 - 0.052 13.6 0.6 0.24 11.5 0.6 2.1 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain AAA PF00004.29 KEY73453.1 - 4.4e-16 59.5 0.0 1.2e-15 58.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY73453.1 - 0.011 16.2 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KEY73453.1 - 0.04 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 KEY73453.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 KEY73453.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Phage_lysozyme PF00959.19 KEY73454.1 - 3.2e-16 59.7 0.0 4.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme DUF4992 PF16383.5 KEY73454.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function HET PF06985.11 KEY73455.1 - 6e-29 101.3 0.0 1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 KEY73456.1 - 0.0057 17.1 0.5 0.0057 17.1 0.5 3.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY73456.1 - 0.47 11.4 0.2 0.47 11.4 0.2 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger MFS_1 PF07690.16 KEY73458.1 - 2.2e-39 135.4 40.5 2.2e-39 135.4 40.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73458.1 - 4.1e-12 45.7 10.3 4.1e-12 45.7 10.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter HET PF06985.11 KEY73460.1 - 7.3e-05 23.1 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Form_Nir_trans PF01226.17 KEY73460.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Formate/nitrite transporter adh_short PF00106.25 KEY73461.1 - 1.3e-23 83.5 0.2 1.9e-23 82.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73461.1 - 5.3e-20 72.0 0.1 6.5e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73461.1 - 1.6e-06 28.2 0.1 2.4e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 KEY73463.1 - 1.3e-21 77.1 0.0 2.3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73463.1 - 2.2e-11 43.6 0.0 7.5e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_43 PF04616.14 KEY73464.1 - 3.3e-104 348.3 1.7 4.9e-104 347.7 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY73464.1 - 4.6e-41 140.8 0.0 6.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 KEY73464.1 - 0.0094 15.6 0.1 0.031 13.8 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain COesterase PF00135.28 KEY73465.1 - 1.9e-76 258.0 0.0 2.7e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY73465.1 - 3.1e-07 30.5 0.2 1e-06 28.8 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY73465.1 - 5.6e-06 26.0 0.3 1e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEY73465.1 - 0.0062 17.2 0.1 0.012 16.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4259 PF14078.6 KEY73466.1 - 1.2 9.9 4.5 7.8 7.3 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) FAD_binding_3 PF01494.19 KEY73467.1 - 9.2e-23 81.0 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY73467.1 - 8.3e-05 22.0 0.1 0.012 14.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY73467.1 - 0.0008 19.6 0.1 0.0021 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEY73467.1 - 0.0033 16.8 0.2 0.51 9.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KEY73467.1 - 0.012 14.9 0.5 0.053 12.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY73467.1 - 0.043 12.9 0.2 1.8 7.5 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KEY73467.1 - 0.049 14.2 0.2 0.049 14.2 0.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY73467.1 - 0.056 13.0 0.3 0.11 12.1 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amidohydro_1 PF01979.20 KEY73468.1 - 7.1e-22 78.2 0.0 1.6e-21 77.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY73468.1 - 1.5e-10 41.1 0.0 1e-06 28.6 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KEY73468.1 - 0.15 12.4 0.1 0.43 10.9 0.1 1.7 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Zn_clus PF00172.18 KEY73470.1 - 0.0015 18.6 8.0 0.0027 17.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KEY73471.1 - 1.4e-69 234.5 0.0 1.8e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KEY73474.1 - 1.5e-42 144.1 0.7 1.9e-10 41.2 0.0 5.9 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY73474.1 - 6.5e-33 112.4 2.0 9.1e-08 32.2 0.1 8.0 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KEY73474.1 - 4.4e-31 106.0 0.0 1.1e-05 25.6 0.0 11.1 11 2 1 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 KEY73474.1 - 1.8e-29 101.7 4.8 6.9e-07 29.7 0.0 8.8 7 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73474.1 - 2.9e-25 85.5 7.3 0.0026 18.1 0.0 13.4 14 0 0 14 14 14 3 Ankyrin repeat NACHT PF05729.12 KEY73474.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEY73474.1 - 0.002 18.4 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEY73474.1 - 0.013 15.9 0.2 0.051 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KEY73474.1 - 0.11 12.6 0.1 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FA_desaturase PF00487.24 KEY73475.1 - 3.6e-16 59.8 13.6 3.6e-16 59.8 13.6 1.8 1 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEY73475.1 - 5.3e-13 48.9 0.0 9.9e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CMAS PF02353.20 KEY73476.1 - 1.3e-61 208.4 0.0 2.5e-61 207.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEY73476.1 - 6.8e-13 49.1 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73476.1 - 1.7e-10 41.4 0.0 3.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73476.1 - 1.3e-09 38.0 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY73476.1 - 2.3e-09 37.3 0.0 3.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY73476.1 - 6.7e-07 30.0 0.0 1.4e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dymeclin PF09742.9 KEY73476.1 - 0.011 14.2 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Methyltransf_PK PF05891.12 KEY73476.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.20 KEY73476.1 - 0.057 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.10 KEY73476.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit adh_short PF00106.25 KEY73477.1 - 2.3e-44 151.2 5.0 2.6e-44 151.0 5.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73477.1 - 4.4e-36 124.6 3.5 5e-36 124.4 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73477.1 - 3.3e-17 63.0 1.6 4.4e-17 62.6 1.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY73477.1 - 5.8e-08 32.5 0.8 1.1e-07 31.6 0.8 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEY73477.1 - 1.6e-05 25.2 0.4 2.4e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KEY73477.1 - 0.00029 20.0 0.4 0.00042 19.5 0.4 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEY73477.1 - 0.00041 19.9 0.1 0.00061 19.3 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEY73477.1 - 0.0029 17.5 0.7 0.0037 17.2 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KEY73477.1 - 0.057 12.8 0.8 0.1 12.0 0.5 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KEY73477.1 - 0.44 10.6 5.2 3.1 7.9 5.2 2.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_31 PF13847.6 KEY73478.1 - 1.5e-11 44.3 0.0 4.6e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY73478.1 - 6.8e-11 42.3 0.0 9.7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73478.1 - 4.3e-09 37.0 0.0 8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73478.1 - 6.3e-08 33.2 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY73478.1 - 4.8e-06 26.1 0.0 8.6e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEY73478.1 - 5e-05 24.0 0.0 9.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEY73478.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ABC_membrane PF00664.23 KEY73479.1 - 1.8e-87 293.5 35.1 5.6e-50 170.5 5.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEY73479.1 - 2.3e-65 219.2 0.1 2.6e-32 112.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KEY73479.1 - 1.1e-13 51.1 0.2 0.001 18.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KEY73479.1 - 7.9e-09 35.1 0.0 0.00068 19.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 KEY73479.1 - 5.7e-08 32.4 0.3 0.012 15.3 0.1 3.2 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEY73479.1 - 2.2e-07 31.0 2.9 0.82 9.4 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEY73479.1 - 8.3e-07 29.1 0.1 0.0026 17.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KEY73479.1 - 4.1e-06 26.6 5.4 0.01 15.6 0.2 4.1 3 1 0 3 3 3 2 AAA domain APS_kinase PF01583.20 KEY73479.1 - 1.4e-05 25.0 0.3 0.098 12.5 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_22 PF13401.6 KEY73479.1 - 1.7e-05 25.2 1.1 0.28 11.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KEY73479.1 - 3.5e-05 22.8 0.6 0.0007 18.5 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KEY73479.1 - 4.8e-05 23.8 7.5 0.11 12.9 0.3 4.1 3 2 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KEY73479.1 - 5.2e-05 23.8 0.2 0.39 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF3987 PF13148.6 KEY73479.1 - 0.0001 21.5 0.1 0.36 9.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3987) AAA_33 PF13671.6 KEY73479.1 - 0.00065 19.9 0.1 0.44 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY73479.1 - 0.0015 19.1 0.1 2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEY73479.1 - 0.0019 18.2 0.5 2.1 8.4 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 KEY73479.1 - 0.0048 17.1 1.3 5.4 7.3 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KEY73479.1 - 0.0063 15.7 0.2 2.3 7.3 0.0 2.5 3 0 0 3 3 2 1 NB-ARC domain AAA_25 PF13481.6 KEY73479.1 - 0.01 15.4 1.0 2.6 7.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 KEY73479.1 - 0.016 15.6 0.9 23 5.4 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KEY73479.1 - 0.048 12.8 0.0 6.7 5.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 KEY73479.1 - 0.057 13.5 0.5 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KEY73479.1 - 0.058 13.1 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KEY73479.1 - 0.077 12.7 0.3 11 5.6 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KEY73479.1 - 0.078 13.0 0.2 10 6.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) KdpD PF02702.17 KEY73479.1 - 0.094 12.2 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_17 PF13207.6 KEY73479.1 - 0.097 13.1 0.9 15 6.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KEY73479.1 - 0.12 12.3 0.4 5.5 6.9 0.0 2.7 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.22 KEY73479.1 - 0.14 12.5 0.1 10 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 KEY73479.1 - 0.17 11.5 0.0 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KEY73479.1 - 0.21 11.1 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KEY73479.1 - 0.25 11.0 1.2 12 5.5 0.1 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pec_lyase_C PF00544.19 KEY73480.1 - 3.7e-41 141.0 5.3 5.2e-41 140.5 5.3 1.2 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_61 PF03443.14 KEY73481.1 - 1.6e-57 194.7 0.3 2e-57 194.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KEY73481.1 - 0.022 15.4 1.5 0.052 14.2 1.5 1.6 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading TPP_enzyme_N PF02776.18 KEY73481.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ras PF00071.22 KEY73482.1 - 1.3e-37 128.9 0.0 1.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY73482.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEY73482.1 - 0.0016 18.0 0.1 0.0076 15.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.20 KEY73482.1 - 0.0054 15.9 0.2 0.011 14.9 0.2 1.5 1 0 0 1 1 1 1 G-protein alpha subunit Helo_like_N PF17111.5 KEY73482.1 - 0.01 15.2 3.5 0.057 12.8 0.1 2.4 1 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins SRPRB PF09439.10 KEY73482.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 KEY73482.1 - 0.041 13.2 0.2 0.09 12.1 0.0 1.6 2 0 0 2 2 2 0 AIG1 family MMR_HSR1 PF01926.23 KEY73482.1 - 0.051 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 KEY73482.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 KEY73482.1 - 0.065 12.4 0.0 3.9 6.6 0.0 2.6 1 1 1 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KEY73482.1 - 0.076 13.3 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KEY73484.1 - 0.2 11.2 0.6 17 4.9 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Yqai PF09466.10 KEY73484.1 - 0.79 10.1 12.8 0.79 10.1 0.3 5.3 1 1 5 6 6 6 0 Hypothetical protein Yqai DUF2795 PF11387.8 KEY73484.1 - 9.2 6.6 14.0 1.4e+02 2.8 0.0 6.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2795) CVNH PF08881.10 KEY73487.1 - 3e-26 92.0 0.1 3.3e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 CVNH domain CD4-extracel PF09191.10 KEY73487.1 - 0.064 13.7 0.1 0.18 12.2 0.0 1.6 1 1 0 2 2 2 0 CD4, extracellular FAD_binding_3 PF01494.19 KEY73489.1 - 1.5e-64 218.5 0.0 1.3e-63 215.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEY73489.1 - 4.2e-07 30.1 0.0 9.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 KEY73489.1 - 0.0012 19.0 0.1 0.004 17.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY73489.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY73489.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KEY73489.1 - 0.16 11.0 0.2 0.34 9.9 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KEY73489.1 - 0.24 10.9 2.5 0.75 9.3 0.4 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KEY73490.1 - 5.1e-23 81.6 73.9 1.1e-18 67.3 40.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KEY73491.1 - 1.1e-47 162.8 0.0 1.6e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73491.1 - 6.2e-36 124.1 0.0 9.6e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEY73491.1 - 0.0027 16.8 0.2 0.013 14.6 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY73491.1 - 0.021 14.1 0.6 0.15 11.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY73491.1 - 0.025 14.2 4.5 0.03 13.9 1.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY73491.1 - 0.03 13.6 0.6 2.4 7.3 1.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 KEY73491.1 - 0.045 13.6 0.1 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif NAD_binding_8 PF13450.6 KEY73491.1 - 0.22 11.8 4.7 0.13 12.5 0.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Malic_M PF03949.15 KEY73491.1 - 0.29 10.4 1.0 0.59 9.4 1.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Tyrosinase PF00264.20 KEY73492.1 - 5e-31 108.7 3.3 4.5e-30 105.6 3.3 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_43 PF04616.14 KEY73494.1 - 3e-52 177.7 2.4 4e-52 177.3 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY73494.1 - 1.7e-28 99.7 0.0 2.8e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 KEY73494.1 - 0.0011 17.8 0.4 0.022 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5005) Sugar_tr PF00083.24 KEY73495.1 - 1.1e-99 334.3 19.1 1.3e-99 334.1 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73495.1 - 1.5e-34 119.5 26.7 7.4e-26 90.9 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KEY73495.1 - 0.0023 17.0 2.2 0.0023 17.0 2.2 2.2 2 0 0 2 2 2 1 PUCC protein MFS_1_like PF12832.7 KEY73495.1 - 0.013 14.4 15.2 0.32 9.8 4.3 3.2 1 1 1 2 2 2 0 MFS_1 like family OATP PF03137.20 KEY73495.1 - 1.5 7.0 14.0 0.59 8.3 1.2 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HATPase_c PF02518.26 KEY73497.1 - 6.2e-25 87.9 0.0 1.3e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY73497.1 - 7.9e-24 84.0 0.2 2e-23 82.7 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY73497.1 - 1.2e-15 57.2 0.2 4e-15 55.6 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KEY73497.1 - 8.1e-10 38.9 0.0 5.9e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KEY73497.1 - 7.1e-09 35.9 0.0 8.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KEY73497.1 - 6.7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold NAD_binding_10 PF13460.6 KEY73498.1 - 3.4e-22 79.2 0.0 4.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY73498.1 - 4.1e-09 36.3 0.0 9e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KEY73498.1 - 8.1e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 KEY73499.1 - 7.8e-09 35.5 11.0 1.3e-08 34.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 KEY73500.1 - 7.4e-13 49.5 1.1 1.1e-12 49.0 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KEY73501.1 - 1.1e-32 113.3 31.1 1.4e-31 109.7 32.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Pro_Al_protease PF02983.14 KEY73502.1 - 7.3e-13 48.4 0.1 7.3e-13 48.4 0.1 2.2 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KEY73502.1 - 1.7e-07 31.3 11.7 9e-07 28.9 11.7 1.9 1 1 0 1 1 1 1 Trypsin HTH_AsnC-type PF13404.6 KEY73502.1 - 0.37 10.7 1.3 6.7 6.6 0.1 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Tannase PF07519.11 KEY73503.1 - 1.7e-92 310.8 0.0 2.6e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KEY73503.1 - 0.047 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Amidase PF01425.21 KEY73504.1 - 5.4e-77 259.7 0.4 4.4e-73 246.8 0.1 2.6 2 1 0 2 2 2 2 Amidase Ferric_reduct PF01794.19 KEY73505.1 - 8.1e-22 77.7 13.7 2.7e-21 76.0 13.7 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY73505.1 - 1.1e-08 35.3 0.0 0.0042 17.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY73505.1 - 0.00091 19.3 0.0 0.0065 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KEY73505.1 - 0.023 15.3 0.0 0.056 14.1 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain zf-MYND PF01753.18 KEY73506.1 - 3.1e-10 39.9 13.4 5.4e-10 39.2 13.4 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KEY73506.1 - 0.00063 20.0 10.9 0.0012 19.1 10.9 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KEY73506.1 - 2.9 7.8 11.5 46 4.0 11.5 2.3 1 1 0 1 1 1 0 HIT zinc finger GMC_oxred_N PF00732.19 KEY73507.1 - 7.3e-27 94.5 5.8 1.2e-21 77.4 0.4 3.1 1 1 2 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73507.1 - 3.7e-25 89.1 0.1 9.8e-25 87.8 0.1 1.8 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEY73507.1 - 3.7e-05 23.1 0.1 5.4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEY73507.1 - 0.00027 20.1 0.4 0.00059 19.0 0.4 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEY73507.1 - 0.0016 17.6 5.3 0.03 13.4 0.9 2.3 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 KEY73507.1 - 0.0028 17.3 6.7 0.018 14.7 1.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEY73507.1 - 0.019 13.7 0.7 0.033 12.9 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KEY73507.1 - 0.021 14.1 0.3 0.044 13.0 0.3 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KEY73507.1 - 0.081 13.2 0.2 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SLAC1 PF03595.17 KEY73508.1 - 4.9e-66 223.2 44.4 5.6e-66 223.0 44.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_61 PF03443.14 KEY73509.1 - 1.8e-57 194.6 0.2 2.1e-57 194.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KEY73509.1 - 0.035 14.4 0.1 0.32 11.3 0.0 2.4 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Pectate_lyase PF03211.13 KEY73510.1 - 3.2e-80 268.4 0.4 4.1e-80 268.1 0.4 1.1 1 0 0 1 1 1 1 Pectate lyase Collagen PF01391.18 KEY73511.1 - 2.2e-15 56.1 84.7 1.5e-08 34.2 29.3 4.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) p450 PF00067.22 KEY73512.1 - 9.1e-40 136.8 0.0 2.7e-39 135.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KEY73513.1 - 1.1e-08 35.1 0.0 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY73513.1 - 3.1e-07 31.2 0.0 3.2e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY73513.1 - 3.2e-05 23.3 0.0 5.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KEY73513.1 - 0.0025 17.7 0.0 0.0033 17.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase DUF3089 PF11288.8 KEY73513.1 - 0.024 14.2 0.1 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.7 KEY73513.1 - 0.055 13.2 0.0 0.77 9.5 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family Phage_DsbA PF11126.8 KEY73515.1 - 0.063 13.5 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator DsbA Ank_2 PF12796.7 KEY73516.1 - 2.3e-31 108.2 0.5 1.2e-13 51.4 0.3 5.1 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73516.1 - 2.5e-23 82.1 1.9 0.0013 19.2 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Pkinase PF00069.25 KEY73516.1 - 4e-23 82.1 0.0 6.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 KEY73516.1 - 2.7e-22 78.2 6.8 0.0039 17.6 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 KEY73516.1 - 9.4e-22 74.8 0.2 0.0037 17.6 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KEY73516.1 - 1e-17 64.0 2.8 0.00028 21.1 0.1 6.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KEY73516.1 - 2e-16 60.0 0.0 3.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KEY73516.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cerato-platanin PF07249.12 KEY73517.1 - 0.0022 18.1 0.1 0.0022 18.1 0.1 2.4 3 0 0 3 3 3 1 Cerato-platanin Bac_rhamnosid6H PF17389.2 KEY73518.1 - 1.1e-116 389.8 0.0 1.5e-116 389.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KEY73518.1 - 9.1e-45 152.6 0.0 1.8e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KEY73518.1 - 8.1e-27 93.2 0.0 1.6e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KEY73518.1 - 2.4e-21 75.3 0.1 6.8e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 KEY73519.1 - 1.4e-89 301.1 31.6 1.6e-89 300.9 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73519.1 - 1.2e-26 93.5 40.6 1.6e-26 93.1 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MacB_PCD PF12704.7 KEY73519.1 - 0.12 12.7 1.1 0.26 11.6 1.1 1.6 1 0 0 1 1 1 0 MacB-like periplasmic core domain Bac_rhamnosid6H PF17389.2 KEY73520.1 - 4.7e-10 39.3 1.0 8.3e-10 38.4 0.5 1.6 1 1 1 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KEY73520.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KEY73520.1 - 0.0027 16.6 0.4 0.0042 16.0 0.4 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KEY73520.1 - 0.01 14.8 0.5 0.13 11.2 0.5 2.1 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF998 PF06197.13 KEY73521.1 - 0.0036 16.9 7.8 0.0082 15.8 7.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Na_H_Exchanger PF00999.21 KEY73523.1 - 7.8e-59 199.4 47.9 1.1e-58 198.9 47.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NUDIX_4 PF14815.6 KEY73524.1 - 6.3e-19 68.0 0.1 1.4e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KEY73524.1 - 1.2e-18 67.5 0.0 2.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEY73524.1 - 1.3e-07 31.1 0.1 2.9e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif NUDIX PF00293.28 KEY73524.1 - 0.01 15.9 0.1 0.032 14.3 0.1 1.8 1 0 0 1 1 1 0 NUDIX domain DnaA_N PF11638.8 KEY73524.1 - 0.14 12.0 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain Cofilin_ADF PF00241.20 KEY73525.1 - 1.9e-22 79.3 0.0 2.1e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AA_permease_2 PF13520.6 KEY73526.1 - 1.8e-45 155.5 52.9 2.3e-45 155.2 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY73526.1 - 1.5e-24 86.4 46.3 2e-24 86.1 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 KEY73526.1 - 0.13 12.2 0.4 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) CBM_21 PF03370.13 KEY73529.1 - 2.6e-34 117.8 0.1 4.2e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KEY73529.1 - 5.8e-10 39.6 0.2 1.3e-09 38.5 0.2 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Shikimate_dh_N PF08501.11 KEY73530.1 - 1.9e-20 72.9 0.0 4.1e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KEY73530.1 - 1.4e-06 28.0 0.2 3.5e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KEY73530.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.24 KEY73531.1 - 1.3e-34 119.5 0.6 3.3e-34 118.2 0.2 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.19 KEY73532.1 - 2.3e-61 205.5 0.2 2.6e-61 205.3 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sugar_tr PF00083.24 KEY73533.1 - 2.1e-130 435.6 20.3 2.4e-130 435.4 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73533.1 - 6.9e-23 81.1 29.0 6.9e-23 81.1 29.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KEY73534.1 - 6.9e-07 29.3 12.3 1.3e-06 28.4 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY73534.1 - 5.2e-05 22.4 1.2 0.014 14.4 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Shikimate_dh_N PF08501.11 KEY73536.1 - 9.6e-18 64.2 0.0 2.2e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KEY73536.1 - 3.6e-15 56.8 0.0 6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 KEY73536.1 - 2.4e-10 40.0 0.0 6.3e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 KEY73536.1 - 6.2e-10 39.4 0.0 1.1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 KEY73536.1 - 1e-06 28.8 0.2 2.8e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 KEY73536.1 - 0.0064 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AAA_8 PF12780.7 KEY73536.1 - 0.016 14.5 0.1 0.033 13.5 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 ABC_tran PF00005.27 KEY73536.1 - 0.022 15.3 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KEY73536.1 - 0.043 14.0 0.2 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEY73536.1 - 0.054 14.0 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Ins134_P3_kin_N PF17927.1 KEY73536.1 - 0.085 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain AAA_22 PF13401.6 KEY73536.1 - 0.098 12.9 0.3 0.5 10.6 0.3 2.1 2 1 0 2 2 1 0 AAA domain NACHT PF05729.12 KEY73536.1 - 0.1 12.5 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KEY73536.1 - 0.13 12.6 0.1 0.58 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain F420_oxidored PF03807.17 KEY73536.1 - 0.19 12.3 0.1 1.4 9.5 0.0 2.4 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.23 KEY73538.1 - 4.4e-22 78.3 0.5 8.6e-22 77.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY73538.1 - 0.0071 16.4 1.2 0.019 15.1 0.0 2.3 3 0 0 3 3 3 1 Berberine and berberine like Ank_5 PF13857.6 KEY73540.1 - 2.4e-10 40.5 0.0 1.9e-05 24.9 0.0 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY73540.1 - 2.5e-09 37.6 0.0 1.5e-05 25.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73540.1 - 4e-07 30.4 0.0 0.013 16.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY73540.1 - 9.9e-05 22.6 0.2 0.9 10.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KEY73540.1 - 0.00074 19.8 0.1 1.3 9.9 0.1 3.6 3 1 0 3 3 3 1 Ankyrin repeat GDPD PF03009.17 KEY73541.1 - 0.00057 19.7 0.0 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF3990 PF13151.6 KEY73542.1 - 0.014 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) FAM199X PF15814.5 KEY73542.1 - 0.8 8.7 5.9 1.2 8.1 5.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF1768 PF08719.11 KEY73543.1 - 1.2e-53 181.7 0.1 1.4e-53 181.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HTH_24 PF13412.6 KEY73543.1 - 0.12 12.0 0.2 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Peptidase_M49 PF03571.15 KEY73545.1 - 2.7e-190 633.4 0.0 3.4e-190 633.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KEY73545.1 - 0.012 15.8 0.3 0.12 12.6 0.1 2.7 3 0 0 3 3 3 0 2-cysteine adaptor domain Peptidase_M24 PF00557.24 KEY73546.1 - 7.9e-56 189.1 0.1 1.6e-55 188.1 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEY73546.1 - 6.3e-25 87.3 0.0 1.2e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Spt20 PF12090.8 KEY73546.1 - 0.49 10.0 6.5 0.83 9.2 6.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KEY73546.1 - 0.74 9.7 6.0 1.2 9.1 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MutL PF13941.6 KEY73547.1 - 0.0013 17.5 0.0 0.032 12.9 0.0 2.5 2 1 1 3 3 3 1 MutL protein BcrAD_BadFG PF01869.20 KEY73547.1 - 0.0039 16.7 0.1 0.11 12.0 0.0 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Actin PF00022.19 KEY73547.1 - 0.028 13.0 0.0 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 Actin HeLo PF14479.6 KEY73549.1 - 2e-06 27.8 0.2 0.031 14.1 0.1 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation NFACT-R_1 PF05670.13 KEY73550.1 - 2.6e-36 124.6 0.1 5.4e-35 120.3 0.1 2.2 1 1 0 1 1 1 1 NFACT protein RNA binding domain NACHT PF05729.12 KEY73551.1 - 1.4e-08 34.8 0.0 5e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KEY73551.1 - 0.00031 20.9 0.2 0.43 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Helo_like_N PF17111.5 KEY73551.1 - 0.00033 20.1 8.0 0.00075 18.9 8.0 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEY73551.1 - 0.0099 16.1 3.9 0.014 15.6 1.9 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 KEY73551.1 - 0.018 15.6 0.1 0.082 13.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 KEY73551.1 - 0.021 15.1 1.5 0.4 10.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KEY73551.1 - 0.048 13.4 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynactin_p22 PF07426.11 KEY73551.1 - 0.082 12.8 3.8 0.16 11.8 3.8 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 Viral_helicase1 PF01443.18 KEY73551.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KEY73551.1 - 0.15 12.5 0.1 0.48 10.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 KEY73551.1 - 0.16 12.5 1.2 0.37 11.3 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEY73551.1 - 0.21 11.3 0.6 0.55 10.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY73551.1 - 0.38 11.1 4.5 2.2 8.6 0.0 3.8 2 2 1 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 KEY73551.1 - 0.46 11.0 0.0 0.46 11.0 0.0 2.7 3 1 0 3 3 2 0 AAA domain Velvet PF11754.8 KEY73552.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Velvet factor BolA PF01722.18 KEY73554.1 - 1.3e-10 41.3 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein ACC_central PF08326.12 KEY73555.1 - 1.1e-274 913.3 0.0 1.3e-274 913.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KEY73555.1 - 8.3e-184 611.8 0.0 1.2e-183 611.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KEY73555.1 - 1.1e-52 178.6 0.0 2.1e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEY73555.1 - 1.8e-27 96.1 0.1 3.7e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEY73555.1 - 8.4e-23 80.5 0.0 1.1e-19 70.6 0.0 3.0 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEY73555.1 - 2.1e-17 62.7 0.1 6e-17 61.2 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KEY73555.1 - 0.00069 19.8 0.0 0.0083 16.3 0.0 2.3 2 0 0 2 2 2 1 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp_3 PF02655.14 KEY73555.1 - 0.0095 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEY73555.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KEY73555.1 - 0.034 14.0 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KEY73555.1 - 0.1 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KEY73555.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain NUDE_C PF04880.13 KEY73556.1 - 2.7e-39 135.5 11.2 2.7e-39 135.5 11.2 3.8 2 1 1 4 4 2 1 NUDE protein, C-terminal conserved region ERM PF00769.19 KEY73556.1 - 0.013 15.3 30.0 0.025 14.4 30.0 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 KEY73556.1 - 0.02 15.0 30.9 3.9 7.6 20.7 3.8 2 1 1 3 3 3 0 Tropomyosin like Chibby PF14645.6 KEY73556.1 - 0.15 12.4 13.4 0.94 9.9 5.2 2.5 1 1 1 2 2 2 0 Chibby family Fez1 PF06818.15 KEY73556.1 - 0.19 12.1 28.1 1.1 9.7 16.7 2.9 2 1 1 3 3 3 0 Fez1 YjbH PF06082.11 KEY73556.1 - 0.61 8.8 6.1 0.88 8.3 6.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH GAS PF13851.6 KEY73556.1 - 0.88 8.9 28.8 0.18 11.2 3.7 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Dynamitin PF04912.14 KEY73556.1 - 1.2 8.4 25.4 0.7 9.2 5.2 2.4 2 1 1 3 3 3 0 Dynamitin PSII_Pbs27 PF13326.6 KEY73556.1 - 2.2 8.6 7.4 0.17 12.2 2.3 1.7 2 0 0 2 2 2 0 Photosystem II Pbs27 Spc7 PF08317.11 KEY73556.1 - 2.5 6.9 24.4 5.2 5.9 24.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KEY73556.1 - 3.6 8.3 19.5 0.1 13.2 4.5 2.9 3 0 0 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KEY73556.1 - 6.1 6.9 36.5 1.1 9.3 11.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KEY73556.1 - 6.6 6.2 31.0 8.4 5.9 29.6 1.8 2 1 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.6 KEY73556.1 - 8.4 4.9 18.0 12 4.4 18.0 1.1 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 KEY73556.1 - 9.3 6.8 35.1 0.058 13.8 8.0 4.0 2 1 2 4 4 4 0 Cell division protein ZapB Peptidase_S46 PF10459.9 KEY73556.1 - 9.9 4.7 11.5 13 4.2 11.5 1.1 1 0 0 1 1 1 0 Peptidase S46 RINGv PF12906.7 KEY73557.1 - 4.5e-17 61.9 8.5 8.8e-17 61.0 8.5 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KEY73557.1 - 0.019 15.3 8.0 0.034 14.5 8.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KEY73557.1 - 0.18 11.9 4.8 0.34 11.0 3.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_PEP_C PF04513.12 KEY73559.1 - 0.0051 16.9 0.2 0.0051 16.9 0.2 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4150 PF13665.6 KEY73559.1 - 3.9 7.7 10.5 5.4 7.2 0.5 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4150) GlutR_dimer PF00745.20 KEY73559.1 - 8.5 6.9 8.3 9 6.8 0.5 3.3 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Gln-synt_C PF00120.24 KEY73560.1 - 2.7e-75 253.5 0.0 3.5e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF5372 PF17342.2 KEY73560.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5372) GMC_oxred_N PF00732.19 KEY73561.1 - 2.8e-60 204.2 0.0 3.8e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73561.1 - 2.5e-34 118.9 0.0 6e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEY73561.1 - 9.2e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY73561.1 - 5.3e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY73561.1 - 0.00066 18.9 0.0 0.0087 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEY73561.1 - 0.0015 17.7 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEY73561.1 - 0.0016 17.7 0.0 0.0042 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY73561.1 - 0.0045 16.3 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY73561.1 - 0.052 12.3 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KEY73561.1 - 0.21 12.2 0.3 1.1 9.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 KEY73562.1 - 2.2e-20 72.5 3.3 2.2e-20 72.5 3.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY73562.1 - 3.7e-12 46.3 0.0 1.1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEY73562.1 - 0.00012 21.5 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEY73562.1 - 0.00093 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEY73562.1 - 0.045 13.6 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEY73562.1 - 0.11 11.8 1.9 0.18 11.1 1.9 1.2 1 0 0 1 1 1 0 ThiF family Fungal_trans_2 PF11951.8 KEY73563.1 - 0.0033 16.3 0.1 0.0068 15.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY73564.1 - 1e-14 54.3 25.8 8.2e-11 41.4 15.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromo PF00385.24 KEY73565.1 - 4.8e-07 29.6 4.9 4.2e-05 23.4 0.2 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc5 PF03221.16 KEY73566.1 - 9.3e-09 35.2 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KEY73566.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain MFS_1 PF07690.16 KEY73567.1 - 2.3e-07 30.1 1.8 2.9e-07 29.8 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73567.1 - 0.00015 20.8 1.2 0.0002 20.4 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LRR_4 PF12799.7 KEY73567.1 - 0.18 12.2 0.4 2.1 8.9 0.1 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Cyclin_N PF00134.23 KEY73570.1 - 7.4e-36 122.7 0.0 1.8e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEY73570.1 - 2.4e-33 114.7 0.2 4.6e-33 113.8 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Dimer_Tnp_hAT PF05699.14 KEY73571.1 - 8.6e-12 44.7 0.3 8.6e-12 44.7 0.3 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KEY73571.1 - 0.0014 19.0 0.1 0.0023 18.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Sulfotransfer_4 PF17784.1 KEY73571.1 - 0.078 12.8 2.9 0.064 13.1 1.7 1.5 1 1 0 1 1 1 0 Sulfotransferase domain Glyco_hydro_12 PF01670.16 KEY73573.1 - 6e-52 176.7 3.3 1e-51 175.9 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ank_2 PF12796.7 KEY73573.1 - 4.6e-09 36.8 0.0 9.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73573.1 - 4.6e-09 36.6 0.0 0.00016 22.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73573.1 - 6.7e-05 23.0 0.0 0.00045 20.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KEY73573.1 - 0.00058 20.2 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KEY73573.1 - 0.0062 16.8 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ADH_zinc_N_2 PF13602.6 KEY73574.1 - 5.4e-08 34.0 0.0 6.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_32N PF00251.20 KEY73576.1 - 2.5e-73 247.3 0.1 2.9e-73 247.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY73576.1 - 7.6e-25 87.7 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KEY73576.1 - 0.072 13.1 0.8 0.45 10.7 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KEY73576.1 - 0.13 11.0 0.4 0.96 8.2 0.0 1.9 1 1 1 2 2 2 0 Sortilin, neurotensin receptor 3, Glyco_hydro_32N PF00251.20 KEY73577.1 - 1.3e-71 241.7 1.4 1.7e-71 241.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY73577.1 - 7.9e-21 74.7 0.1 1.4e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KEY73578.1 - 1.1e-61 209.0 0.0 1.8e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY73578.1 - 3e-15 56.6 0.0 5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.24 KEY73579.1 - 3.1e-114 382.3 24.7 2.1e-66 224.7 0.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEY73579.1 - 5.3e-23 81.5 27.7 1.7e-14 53.5 10.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily CHASE3 PF05227.13 KEY73579.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 CHASE3 domain Transferase PF02458.15 KEY73581.1 - 9.1e-06 24.6 0.0 0.0027 16.4 0.0 2.4 2 1 0 2 2 2 2 Transferase family NACHT PF05729.12 KEY73582.1 - 3e-11 43.5 0.0 7.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73582.1 - 0.00016 22.1 0.0 0.00073 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KEY73582.1 - 0.0015 17.8 0.0 0.0035 16.6 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEY73582.1 - 0.0083 16.4 0.0 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helo_like_N PF17111.5 KEY73582.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA PF00004.29 KEY73582.1 - 0.035 14.5 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEY73582.1 - 0.043 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KEY73582.1 - 0.081 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KEY73582.1 - 0.15 11.4 0.0 0.42 9.9 0.0 1.8 1 1 0 1 1 1 0 KaiC SurE PF01975.17 KEY73583.1 - 9.5e-31 107.1 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.6 KEY73583.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Peripla_BP_4 PF13407.6 KEY73583.1 - 0.19 11.3 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain PP-binding PF00550.25 KEY73584.1 - 6.6e-10 39.2 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site CRISPR_Cse2 PF09485.10 KEY73584.1 - 0.054 14.0 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PS-DH PF14765.6 KEY73585.1 - 5.8e-30 104.6 0.0 9.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KEY73585.1 - 6.8e-18 65.2 0.0 1.9e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEY73585.1 - 7.6e-14 51.8 0.0 2.6e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KEY73585.1 - 3.4e-12 46.5 0.0 6.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73585.1 - 3.1e-11 43.8 0.0 1e-10 42.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73585.1 - 6.2e-11 42.8 0.0 1.7e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73585.1 - 2e-10 40.7 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEY73585.1 - 2.4e-09 38.3 0.0 1.7e-08 35.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 KEY73585.1 - 1.7e-06 27.6 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Rio2_N PF09202.11 KEY73585.1 - 0.075 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Rio2, N-terminal HET PF06985.11 KEY73586.1 - 7.5e-38 130.2 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KEY73586.1 - 0.041 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) p450 PF00067.22 KEY73587.1 - 6.9e-40 137.2 0.0 8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M66 PF10462.9 KEY73588.1 - 0.053 12.5 0.1 0.084 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 SNF2_N PF00176.23 KEY73589.1 - 9.2e-68 228.5 0.2 1.3e-67 228.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY73589.1 - 8.5e-14 51.8 0.1 4.1e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY73589.1 - 1.2e-06 28.6 0.3 3.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KEY73589.1 - 0.0002 21.2 5.3 0.00054 19.9 5.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEY73589.1 - 0.00021 21.1 5.1 0.00051 19.9 5.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEY73589.1 - 0.0031 17.3 5.0 0.0077 16.1 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KEY73589.1 - 0.11 12.7 2.1 0.38 11.0 2.1 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 KEY73589.1 - 0.16 11.8 5.7 0.12 12.3 1.1 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEY73589.1 - 0.24 11.6 2.5 0.59 10.3 2.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KEY73589.1 - 0.47 10.4 5.6 1.4 8.9 5.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEY73589.1 - 0.82 9.7 3.2 1.2 9.3 0.8 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 KEY73589.1 - 1.8 9.0 12.8 0.099 13.0 6.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-P11 PF03854.14 KEY73589.1 - 9.1 6.0 6.9 9.2 6.0 1.3 2.9 3 0 0 3 3 3 0 P-11 zinc finger GT87 PF09594.10 KEY73590.1 - 0.00019 21.2 0.1 0.00029 20.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 SKG6 PF08693.10 KEY73590.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KEY73590.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mid2 PF04478.12 KEY73590.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor NACHT PF05729.12 KEY73591.1 - 2.1e-08 34.3 0.0 6.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73591.1 - 6e-08 33.3 0.8 2.8e-06 27.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KEY73591.1 - 7.3e-06 25.3 0.0 2.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEY73591.1 - 1e-05 25.8 0.3 5.7e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEY73591.1 - 6.9e-05 23.2 0.1 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KEY73591.1 - 0.00011 22.6 0.1 0.00075 19.9 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEY73591.1 - 0.00017 22.1 1.4 0.0021 18.6 0.0 3.0 3 0 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 KEY73591.1 - 0.0018 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.9 KEY73591.1 - 0.0023 17.2 0.0 0.0075 15.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KEY73591.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 KEY73591.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Torsin DUF87 PF01935.17 KEY73591.1 - 0.011 15.9 2.8 0.03 14.4 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain ResIII PF04851.15 KEY73591.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KEY73591.1 - 0.024 14.7 0.1 0.27 11.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEY73591.1 - 0.06 12.4 0.0 0.16 11.0 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KEY73591.1 - 0.064 13.8 2.5 0.31 11.6 0.0 3.6 5 0 0 5 5 4 0 AAA domain AAA_30 PF13604.6 KEY73591.1 - 0.07 12.8 0.9 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEY73591.1 - 0.073 13.0 4.6 0.075 12.9 0.1 3.1 3 1 1 4 4 3 0 NTPase APS_kinase PF01583.20 KEY73591.1 - 0.076 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase_2 PF01637.18 KEY73591.1 - 0.086 12.7 0.0 0.44 10.4 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TFA2_Winged_2 PF18121.1 KEY73591.1 - 0.11 12.2 0.1 8.4 6.2 0.0 2.7 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 DUF977 PF06163.11 KEY73591.1 - 0.19 11.7 1.0 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) AAA_25 PF13481.6 KEY73591.1 - 0.59 9.7 10.9 0.24 11.0 0.2 3.5 3 1 0 3 3 3 0 AAA domain Glyco_transf_54 PF04666.13 KEY73592.1 - 6e-13 48.3 0.0 6.3e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region T5orf172 PF10544.9 KEY73593.1 - 1e-13 51.7 1.1 4.2e-13 49.7 0.1 2.4 2 1 0 2 2 2 1 T5orf172 domain Auxin_inducible PF02519.14 KEY73593.1 - 0.045 13.9 0.5 15 5.8 0.0 3.2 2 1 1 3 3 3 0 Auxin responsive protein GST_N_2 PF13409.6 KEY73594.1 - 3.4e-09 36.9 0.0 6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY73594.1 - 4.1e-08 33.5 0.0 6.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY73594.1 - 0.017 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY73594.1 - 0.032 14.4 0.0 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain VCBS PF13517.6 KEY73595.1 - 3.3e-23 82.0 51.1 3e-10 40.5 1.9 7.8 2 2 6 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KEY73595.1 - 5e-12 46.6 0.2 1.3e-11 45.3 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KEY73595.1 - 1.6e-10 40.7 5.4 0.25 10.7 0.0 5.3 3 1 2 5 5 5 5 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KEY73595.1 - 2.7e-06 27.4 27.8 0.011 15.8 1.1 5.5 5 0 0 5 5 5 3 FG-GAP repeat Dockerin_1 PF00404.18 KEY73595.1 - 0.00084 19.5 11.7 4.2 7.6 0.3 4.9 5 0 0 5 5 5 3 Dockerin type I domain Lipase_GDSL PF00657.22 KEY73595.1 - 0.0018 18.3 0.1 0.0041 17.1 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PliI PF16743.5 KEY73595.1 - 0.079 12.7 0.5 27 4.5 0.0 4.0 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme EF-hand_1 PF00036.32 KEY73595.1 - 1.7 8.4 10.6 1.4 8.7 0.3 4.8 5 0 0 5 5 5 0 EF hand HET PF06985.11 KEY73596.1 - 3.9e-23 82.4 0.0 1.8e-22 80.3 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEY73597.1 - 1e-23 84.3 0.0 7e-23 81.6 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KEY73598.1 - 3.4e-35 121.3 0.1 4.2e-35 121.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73598.1 - 1e-28 100.5 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73598.1 - 2.3e-07 30.9 0.1 4.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KEY73598.1 - 0.00067 19.6 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KEY73598.1 - 0.011 15.2 0.1 0.017 14.6 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY73598.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KEY73598.1 - 0.11 12.5 0.3 0.24 11.5 0.3 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1776 PF08643.10 KEY73598.1 - 0.22 10.9 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 KEY73599.1 - 1.4e-29 103.1 49.1 4.4e-28 98.2 47.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Orf78 PF06024.12 KEY73599.1 - 0.036 14.4 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF2834 PF11196.8 KEY73599.1 - 0.13 12.7 6.4 0.24 11.8 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) DUF1772 PF08592.11 KEY73599.1 - 6.1 7.2 19.3 0.41 10.9 0.4 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) p450 PF00067.22 KEY73600.1 - 3.7e-47 161.1 0.0 7.2e-47 160.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 KEY73601.1 - 1.9e-17 63.3 0.1 2.5e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEY73601.1 - 1.7e-06 26.8 3.8 0.0085 14.5 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Methyltransf_2 PF00891.18 KEY73602.1 - 1.2e-23 83.5 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Sigma70_r4 PF04545.16 KEY73602.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KEY73602.1 - 0.19 11.3 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 KEY73603.1 - 1.1e-34 119.9 0.0 3e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KEY73603.1 - 1.1e-28 100.6 8.5 1.1e-28 100.6 8.5 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KEY73603.1 - 3.5e-06 26.6 0.3 0.00059 19.3 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEY73603.1 - 0.0004 20.7 0.2 0.0023 18.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEY73603.1 - 0.0055 16.4 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEY73603.1 - 0.0075 16.7 0.8 0.038 14.4 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KEY73603.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3278 PF11683.8 KEY73603.1 - 0.019 15.0 2.7 0.49 10.5 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) AAA_15 PF13175.6 KEY73603.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 KEY73603.1 - 0.081 11.8 0.3 0.24 10.3 0.3 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_21 PF13304.6 KEY73603.1 - 0.086 12.6 0.2 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KEY73603.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pex24p PF06398.11 KEY73603.1 - 0.32 9.9 1.6 0.83 8.6 1.0 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF5129 PF17173.4 KEY73606.1 - 0.015 14.4 0.3 0.022 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Helicase_C PF00271.31 KEY73608.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain MNNL PF07657.13 KEY73612.1 - 0.16 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 N terminus of Notch ligand SWIRM-assoc_2 PF16496.5 KEY73614.1 - 5.6 5.7 11.0 13 4.6 11.0 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DDE_Tnp_1_7 PF13843.6 KEY73617.1 - 4.5e-41 141.3 0.0 6.5e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 HSR PF03172.13 KEY73617.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 HSR domain Zn_clus PF00172.18 KEY73620.1 - 2.3e-09 37.2 6.7 2.3e-09 37.2 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KEY73620.1 - 0.12 12.1 3.2 0.26 11.1 0.6 2.4 2 0 0 2 2 2 0 Integrin plexin domain DUF1322 PF07032.11 KEY73621.1 - 0.14 12.7 0.2 0.35 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) MBOAT_2 PF13813.6 KEY73623.1 - 2.2e-21 75.9 0.4 2.2e-21 75.9 0.4 1.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.22 KEY73624.1 - 3.5e-57 194.2 0.0 4.4e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KEY73625.1 - 9.3e-21 74.2 0.0 4.4e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73625.1 - 9e-09 35.2 0.0 3.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73625.1 - 5.6e-06 26.4 0.1 9.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY73625.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KEY73626.1 - 4.7e-27 94.8 43.9 7.2e-23 81.1 26.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KEY73627.1 - 5e-32 111.8 2.2 6e-32 111.6 2.2 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KEY73628.1 - 4.1e-66 223.6 0.0 5.1e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KEY73629.1 - 0.045 13.5 1.0 0.069 12.9 0.4 1.6 2 0 0 2 2 2 0 Cupin domain FAD_binding_4 PF01565.23 KEY73630.1 - 2.2e-25 89.0 0.2 4.4e-25 88.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain CTP_transf_1 PF01148.20 KEY73631.1 - 2.3e-79 266.9 24.7 2.9e-79 266.6 24.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SUZ PF12752.7 KEY73631.1 - 0.075 13.8 1.0 0.14 13.0 1.0 1.3 1 0 0 1 1 1 0 SUZ domain Amidase PF01425.21 KEY73632.1 - 6.7e-70 236.3 0.0 1.3e-69 235.3 0.0 1.5 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KEY73633.1 - 1.3e-41 142.7 27.6 1.3e-41 142.7 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73633.1 - 4.2e-18 65.4 10.3 4.2e-18 65.4 10.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEY73633.1 - 2.5e-06 26.2 5.7 3.9e-06 25.6 5.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 KEY73634.1 - 1.1e-08 35.6 4.5 0.0024 18.7 0.0 7.5 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY73634.1 - 2.5e-06 27.7 0.1 2.2 8.7 0.0 5.1 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KEY73634.1 - 1.8e-05 24.6 0.1 0.00041 20.1 0.0 2.5 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KEY73634.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEY73634.1 - 0.0027 18.3 0.0 0.0077 16.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 KEY73634.1 - 0.018 14.9 0.4 0.084 12.8 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF829) Fructosamin_kin PF03881.14 KEY73635.1 - 6e-34 117.6 2.7 8.7e-34 117.0 2.7 1.1 1 0 0 1 1 1 1 Fructosamine kinase SnoaL PF07366.12 KEY73636.1 - 0.007 16.2 0.1 0.016 15.0 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY73636.1 - 0.045 14.4 0.2 0.11 13.1 0.1 1.7 2 0 0 2 2 2 0 SnoaL-like domain DHDPS PF00701.22 KEY73637.1 - 3.8e-40 137.4 0.0 4.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TFR_dimer PF04253.15 KEY73638.1 - 6.9e-25 87.5 0.0 1.2e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEY73638.1 - 1.1e-21 77.4 0.0 4.1e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KEY73638.1 - 2.2e-10 40.4 0.3 9.5e-10 38.4 0.1 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KEY73638.1 - 0.0032 17.2 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KEY73638.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin TPR_12 PF13424.6 KEY73639.1 - 1.1e-06 28.8 0.2 2.8e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY73639.1 - 0.00011 22.0 0.5 0.00052 19.8 0.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73639.1 - 0.00042 20.2 0.3 0.0011 18.9 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73639.1 - 0.0022 17.8 0.0 0.0081 15.9 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73639.1 - 0.0034 17.3 0.1 0.0066 16.4 0.1 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73639.1 - 0.0035 17.4 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Retrotrans_gag PF03732.17 KEY73641.1 - 1.8e-09 37.7 0.3 1.8e-09 37.7 0.3 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KEY73641.1 - 2.7e-06 27.2 0.0 1e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apolipoprotein PF01442.18 KEY73641.1 - 0.00047 20.1 14.2 0.0011 18.8 10.5 2.4 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain FH2 PF02181.23 KEY73641.1 - 0.0084 15.3 1.1 0.016 14.4 1.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Spc7 PF08317.11 KEY73641.1 - 0.41 9.5 11.0 1.1 8.0 11.0 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3158 PF11358.8 KEY73641.1 - 0.5 10.1 4.1 0.51 10.1 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3158) Fzo_mitofusin PF04799.13 KEY73641.1 - 5.4 6.5 6.8 1.5 8.4 3.4 1.7 2 0 0 2 2 2 0 fzo-like conserved region Synaptobrevin PF00957.21 KEY73641.1 - 5.6 6.8 5.8 19 5.2 5.2 2.1 1 1 1 2 2 2 0 Synaptobrevin DUF2205 PF10224.9 KEY73641.1 - 7.2 6.7 7.3 1.8 8.6 0.1 2.7 2 0 0 2 2 2 0 Short coiled-coil protein TPR_10 PF13374.6 KEY73642.1 - 5e-51 169.3 0.5 8.6e-12 44.5 0.3 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73642.1 - 2.2e-32 111.2 2.8 9.1e-13 48.3 0.1 4.3 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73642.1 - 6.8e-18 63.3 0.1 0.0031 17.4 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73642.1 - 2e-09 37.9 0.0 0.6 10.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73642.1 - 3.5e-08 33.3 0.2 1.1 9.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73642.1 - 6e-08 32.2 0.1 0.37 11.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73642.1 - 5.1e-07 29.2 0.0 3.4 7.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY73642.1 - 5.4e-07 29.3 3.7 1.6e-05 24.5 2.2 2.3 1 1 1 2 2 2 1 MalT-like TPR region TPR_4 PF07721.14 KEY73642.1 - 7e-07 29.3 0.0 4.8 8.1 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73642.1 - 9.3e-07 28.6 0.2 0.001 19.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73642.1 - 3e-05 24.4 0.1 9 6.9 0.0 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73642.1 - 8.1e-05 23.1 1.8 12 7.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Urocanase_N PF17391.2 KEY73642.1 - 0.015 15.0 0.1 1.1 9.0 0.0 3.1 2 1 2 4 4 4 0 Urocanase N-terminal domain TPR_20 PF14561.6 KEY73642.1 - 0.023 15.0 0.6 1.5 9.2 0.1 3.1 1 1 1 3 3 3 0 Tetratricopeptide repeat Euplotes_phero PF05842.11 KEY73642.1 - 0.047 14.3 0.1 1.6e+02 2.8 0.0 3.6 1 1 3 4 4 4 0 Euplotes octocarinatus mating pheromone protein Ntox35 PF15534.6 KEY73642.1 - 0.065 13.7 2.6 44 4.6 0.1 3.3 1 1 2 3 3 3 0 Bacterial toxin 35 TPR_6 PF13174.6 KEY73642.1 - 0.089 13.5 1.5 13 6.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SOG2 PF10428.9 KEY73643.1 - 4 6.5 6.8 6.2 5.9 6.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_10 PF13374.6 KEY73644.1 - 4.3e-33 112.2 0.1 4.8e-12 45.3 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73644.1 - 7.3e-26 90.3 0.1 1.4e-12 47.7 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73644.1 - 9.4e-14 50.4 0.1 0.0012 18.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73644.1 - 5.4e-09 35.8 0.2 0.14 12.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73644.1 - 7.8e-06 25.5 0.4 0.48 10.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73644.1 - 4.2e-05 23.3 0.0 0.78 10.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY73644.1 - 0.00012 21.6 0.7 0.0079 15.6 0.2 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 KEY73644.1 - 0.00032 21.3 0.0 1.7 9.3 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73644.1 - 0.00045 20.7 0.2 5.1 7.7 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KEY73644.1 - 0.00046 20.4 0.1 1.1 9.5 0.0 2.3 1 1 1 2 2 2 2 Tetratrico peptide repeat TPR_8 PF13181.6 KEY73644.1 - 0.0014 18.6 0.0 3.2 8.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat CutA1 PF03091.15 KEY73644.1 - 0.0017 18.2 0.5 2 8.3 0.0 2.9 3 0 0 3 3 3 1 CutA1 divalent ion tolerance protein TPR_4 PF07721.14 KEY73644.1 - 0.0043 17.5 0.0 5.8 7.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Euplotes_phero PF05842.11 KEY73644.1 - 0.0055 17.3 0.6 2.5 8.7 0.3 2.9 1 1 2 3 3 3 1 Euplotes octocarinatus mating pheromone protein Ntox35 PF15534.6 KEY73644.1 - 0.025 15.0 2.6 12 6.5 0.1 3.0 1 1 2 3 3 3 0 Bacterial toxin 35 TPR_14 PF13428.6 KEY73644.1 - 0.067 14.0 0.4 27 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEY73644.1 - 0.1 13.3 1.4 70 4.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEY73644.1 - 0.11 12.8 0.3 3 8.2 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4747 PF15931.5 KEY73644.1 - 0.21 11.2 1.2 7 6.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4747) GW PF13457.6 KEY73644.1 - 0.64 10.7 2.2 15 6.2 0.1 2.7 2 1 1 3 3 3 0 GW (Gly-Tryp) dipeptide domain DDE_Tnp_1_7 PF13843.6 KEY73645.1 - 9.1e-27 94.3 0.0 7.6e-14 51.8 0.0 2.8 2 1 0 2 2 2 2 Transposase IS4 Beta-lactamase PF00144.24 KEY73646.1 - 1.3e-45 156.1 0.1 1.8e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KEY73646.1 - 0.00078 19.1 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase enzyme family PhyH PF05721.13 KEY73647.1 - 5.5e-16 59.5 0.1 8.3e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KEY73648.1 - 3.1e-19 69.1 45.6 3.1e-19 69.1 45.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY73648.1 - 8.4e-07 27.8 13.4 1.3e-06 27.2 13.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nucleos_tra2_N PF01773.20 KEY73649.1 - 0.076 13.6 0.2 0.076 13.6 0.2 2.3 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Sulfotransfer_4 PF17784.1 KEY73651.1 - 2.4e-56 191.0 0.0 2.8e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY73651.1 - 0.00071 20.0 0.1 0.0045 17.4 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Aurora-A_bind PF09041.10 KEY73651.1 - 0.14 12.2 0.0 18 5.5 0.0 2.3 2 0 0 2 2 2 0 Aurora-A binding ATP_transf PF09830.9 KEY73652.1 - 1.7e-16 60.1 0.0 5.6e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase Abhydrolase_3 PF07859.13 KEY73655.1 - 1.2e-23 84.1 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEY73655.1 - 3.2e-09 36.1 0.0 1.1e-07 31.1 0.0 2.5 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KEY73655.1 - 0.0021 17.0 0.0 0.0035 16.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.19 KEY73656.1 - 1.8e-29 103.1 0.0 2.3e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY73656.1 - 1.9e-05 24.4 0.1 0.0018 17.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY73656.1 - 3.1e-05 23.4 0.2 0.0027 17.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY73656.1 - 0.00022 21.4 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEY73656.1 - 0.006 15.7 0.2 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY73656.1 - 0.046 13.0 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEY73656.1 - 0.081 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KEY73656.1 - 0.12 11.2 0.2 4.4 6.1 0.1 2.4 2 1 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KEY73656.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Baculo_PEP_C PF04513.12 KEY73658.1 - 0.032 14.3 6.5 0.061 13.4 6.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 KEY73659.1 - 3.8e-38 131.3 28.2 8.1e-37 127.0 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pmp3 PF01679.17 KEY73660.1 - 4.8e-11 42.7 6.6 6.2e-11 42.3 6.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator p450 PF00067.22 KEY73661.1 - 8.9e-28 97.2 0.0 1.2e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 KEY73662.1 - 4.4e-17 63.0 0.0 6.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_1 PF00561.20 KEY73663.1 - 9e-12 45.2 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY73663.1 - 1.6e-06 28.9 0.0 2.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY73663.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polysacc_deac_1 PF01522.21 KEY73664.1 - 8e-26 90.4 0.0 1.1e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KEY73664.1 - 0.063 12.5 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 p450 PF00067.22 KEY73665.1 - 3.2e-53 181.1 0.0 4.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Antimicrobial10 PF08105.11 KEY73665.1 - 0.019 15.1 0.1 0.7 10.0 0.0 2.6 2 0 0 2 2 2 0 Metchnikowin family DUF1275 PF06912.11 KEY73666.1 - 1.9e-43 148.6 14.3 2.4e-43 148.3 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4229 PF14012.6 KEY73666.1 - 0.036 14.2 0.2 0.036 14.2 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF4175 PF13779.6 KEY73666.1 - 0.42 8.4 0.7 0.68 7.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpoV PF08183.11 KEY73666.1 - 0.86 9.6 2.0 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Stage V sporulation protein family Oxidored_FMN PF00724.20 KEY73667.1 - 4.1e-33 115.1 0.0 5.2e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KEY73668.1 - 4.6e-10 39.0 0.1 8e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73668.1 - 2.7e-05 24.2 11.3 5.4e-05 23.2 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_34 PF05637.12 KEY73669.1 - 3.6e-07 30.1 0.2 8.3e-07 29.0 0.2 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KEY73669.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sugar_tr PF00083.24 KEY73670.1 - 7.8e-84 282.1 21.7 9.3e-84 281.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73670.1 - 7.2e-27 94.2 61.3 8.3e-25 87.4 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEY73670.1 - 7.2e-07 27.9 3.0 7.2e-07 27.9 3.0 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KEY73670.1 - 0.0041 16.0 5.3 0.0041 16.0 5.3 2.5 2 1 0 2 2 2 2 MFS_1 like family Exosortase_EpsH PF09721.10 KEY73670.1 - 0.0053 16.3 22.4 0.032 13.8 0.0 3.4 1 1 2 3 3 3 2 Transmembrane exosortase (Exosortase_EpsH) Cupin_2 PF07883.11 KEY73671.1 - 0.00016 21.3 0.3 0.00033 20.3 0.3 1.6 1 1 0 1 1 1 1 Cupin domain NAD_binding_8 PF13450.6 KEY73672.1 - 1e-10 41.6 0.0 2.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEY73672.1 - 2.1e-10 40.5 0.0 7e-07 28.9 0.0 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KEY73672.1 - 3.9e-06 26.2 1.3 6.6e-06 25.5 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEY73672.1 - 3.9e-06 25.8 0.6 6.8e-06 25.0 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KEY73672.1 - 6.4e-06 25.6 0.1 9.9e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEY73672.1 - 8.1e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY73672.1 - 1e-05 25.0 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY73672.1 - 2.3e-05 24.1 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY73672.1 - 6.3e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY73672.1 - 0.0008 18.7 0.3 0.0015 17.9 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KEY73672.1 - 0.0045 17.5 0.0 0.082 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY73672.1 - 0.0064 15.6 0.1 0.0096 15.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Peptidase_MA_2 PF13485.6 KEY73672.1 - 0.012 15.4 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily NAD_binding_9 PF13454.6 KEY73672.1 - 0.016 15.2 0.1 0.067 13.2 0.1 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding MCRA PF06100.11 KEY73672.1 - 0.022 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 KEY73672.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KEY73672.1 - 0.076 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KEY73672.1 - 0.17 12.1 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PI3K_1B_p101 PF10486.9 KEY73673.1 - 0.028 12.2 0.0 0.035 11.9 0.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UDPGT PF00201.18 KEY73674.1 - 5.8e-08 32.0 0.0 7.7e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ADH_zinc_N_2 PF13602.6 KEY73675.1 - 1.4e-23 84.4 0.6 2.3e-23 83.7 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY73675.1 - 3.9e-15 56.0 0.6 3.9e-15 56.0 0.6 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY73675.1 - 2.7e-08 33.7 1.8 1.2e-06 28.4 0.0 3.2 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KEY73675.1 - 0.0032 16.8 1.0 0.0032 16.8 1.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DOT1 PF08123.13 KEY73675.1 - 0.013 15.0 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 RmlD_sub_bind PF04321.17 KEY73675.1 - 0.077 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain HSP20 PF00011.21 KEY73676.1 - 1.2e-14 54.2 0.1 1.2e-09 38.2 0.0 2.3 2 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEY73676.1 - 0.019 14.5 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA Prok-E2_E PF14462.6 KEY73676.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E DUF4611 PF15387.6 KEY73676.1 - 0.13 12.5 3.3 0.57 10.4 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PGA2 PF07543.12 KEY73676.1 - 3.1 7.8 5.9 4.5 7.3 5.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Zip PF02535.22 KEY73677.1 - 2.6e-49 168.2 0.1 5.3e-49 167.2 0.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Actin PF00022.19 KEY73679.1 - 3e-100 335.7 0.0 3.6e-99 332.1 0.0 1.9 1 1 0 1 1 1 1 Actin DUF5579 PF17742.1 KEY73679.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Aldo_ket_red PF00248.21 KEY73680.1 - 6.1e-51 173.4 0.0 7.8e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 KEY73681.1 - 1.6e-20 73.0 0.3 1.6e-20 73.0 0.3 3.2 4 0 0 4 4 4 1 DnaJ domain DUF3605 PF12239.8 KEY73681.1 - 0.035 14.4 0.2 0.035 14.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3605) Beta-lactamase PF00144.24 KEY73682.1 - 2.8e-26 92.5 0.6 5.2e-26 91.7 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3810 PF12725.7 KEY73683.1 - 1.9 7.8 5.9 1.9 7.8 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) HET PF06985.11 KEY73684.1 - 1.4e-06 28.7 0.0 0.0018 18.7 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1664 PF07889.12 KEY73685.1 - 0.018 15.1 1.6 0.036 14.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KEY73685.1 - 0.04 14.0 2.6 0.086 12.9 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) PIN_8 PF18476.1 KEY73685.1 - 0.11 12.4 2.5 0.14 12.0 0.2 2.1 1 1 1 2 2 2 0 PIN like domain Apolipoprotein PF01442.18 KEY73685.1 - 0.22 11.4 12.0 0.034 14.0 7.5 1.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain RapA_C PF12137.8 KEY73685.1 - 1.1 8.2 8.6 1.6 7.7 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DDE_Tnp_1_7 PF13843.6 KEY73686.1 - 0.00099 18.5 0.3 0.0018 17.7 0.1 1.5 2 0 0 2 2 2 1 Transposase IS4 Pkinase PF00069.25 KEY73687.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 1 1 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 KEY73687.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_33 PF10017.9 KEY73692.1 - 1.5e-14 53.8 0.1 2.4e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SEN1_N PF12726.7 KEY73692.1 - 0.0052 15.1 0.0 0.0068 14.7 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal bZIP_1 PF00170.21 KEY73693.1 - 0.00014 21.8 9.8 0.00022 21.2 9.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 KEY73693.1 - 0.005 17.1 9.6 0.0079 16.4 9.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KEY73693.1 - 0.019 13.9 4.4 0.022 13.6 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CREPT PF16566.5 KEY73693.1 - 0.02 15.1 1.6 0.028 14.6 1.6 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TipE PF16972.5 KEY73693.1 - 0.047 12.9 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Phage_GP20 PF06810.11 KEY73693.1 - 0.059 13.2 0.5 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 HALZ PF02183.18 KEY73693.1 - 0.072 13.3 0.9 0.19 12.0 0.8 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper SlyX PF04102.12 KEY73693.1 - 0.077 13.6 1.6 0.15 12.7 1.5 1.6 1 1 0 1 1 1 0 SlyX Jnk-SapK_ap_N PF09744.9 KEY73693.1 - 0.13 12.5 5.9 0.17 12.1 5.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 COG5 PF10392.9 KEY73693.1 - 0.32 11.2 3.7 0.47 10.6 3.7 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.19 KEY73693.1 - 0.66 7.8 1.6 0.79 7.6 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PKcGMP_CC PF16808.5 KEY73693.1 - 1 9.3 9.3 0.062 13.2 3.6 1.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5094 PF17015.5 KEY73693.1 - 1.2 9.2 4.4 1.7 8.7 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) bZIP_2 PF07716.15 KEY73693.1 - 2.1 8.5 13.9 3.7 7.7 13.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KEY73693.1 - 3.4 7.5 8.4 0.27 11.0 2.0 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3435 PF11917.8 KEY73695.1 - 2e-60 204.9 0.4 5.5e-60 203.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) HTH_Tnp_Tc5 PF03221.16 KEY73695.1 - 3.8e-06 26.8 0.0 1.4e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Val_tRNA-synt_C PF10458.9 KEY73695.1 - 1.1 9.6 6.1 1.4 9.3 0.9 3.7 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Methyltransf_2 PF00891.18 KEY73696.1 - 1.2e-23 83.5 0.0 1.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KEY73696.1 - 0.039 13.4 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_transf_34 PF05637.12 KEY73697.1 - 2.6e-15 56.8 0.1 1.3e-14 54.5 0.1 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_61 PF03443.14 KEY73698.1 - 7.3e-37 127.3 0.0 1.1e-36 126.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3450 PF11932.8 KEY73699.1 - 0.00055 19.3 1.9 0.00072 18.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.11 KEY73699.1 - 0.0047 17.0 0.1 0.0065 16.5 0.1 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 PI3K_P85_iSH2 PF16454.5 KEY73699.1 - 0.0055 16.3 1.5 0.0077 15.8 1.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 KEY73699.1 - 0.0085 15.8 0.6 0.013 15.3 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator CENP-F_leu_zip PF10473.9 KEY73699.1 - 0.01 15.9 2.3 0.015 15.3 2.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PMEI PF04043.15 KEY73699.1 - 0.033 14.5 0.1 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF4200 PF13863.6 KEY73699.1 - 0.037 14.4 0.1 0.056 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4988 PF16378.5 KEY73699.1 - 0.09 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF4140 PF13600.6 KEY73699.1 - 0.22 12.0 2.5 0.26 11.7 1.7 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pox_A_type_inc PF04508.12 KEY73699.1 - 0.23 11.3 3.3 0.75 9.7 3.3 1.9 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat DUF1002 PF06207.11 KEY73700.1 - 0.03 13.9 0.5 0.034 13.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Apolipoprotein PF01442.18 KEY73700.1 - 0.046 13.6 3.4 0.075 12.9 3.4 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 KEY73700.1 - 0.065 12.8 0.7 0.083 12.5 0.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KEY73700.1 - 0.074 11.6 0.1 0.086 11.4 0.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3150 PF11348.8 KEY73700.1 - 0.11 11.7 1.0 7.7 5.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3150) Phage_X PF05155.15 KEY73700.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage X family DUF4355 PF14265.6 KEY73700.1 - 0.22 11.8 3.8 0.35 11.1 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Methyltransf_3 PF01596.17 KEY73702.1 - 2.9e-25 88.7 0.0 4.3e-25 88.1 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KEY73702.1 - 1.1e-11 45.7 0.0 2.8e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEY73702.1 - 1.4e-08 34.8 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEY73702.1 - 5.2e-06 26.3 0.0 6.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73702.1 - 0.0002 22.0 0.0 0.00032 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY73702.1 - 0.093 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KEY73702.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase SUR7 PF06687.12 KEY73703.1 - 8.2e-17 61.5 9.0 1.2e-16 61.0 9.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF3632 PF12311.8 KEY73703.1 - 0.003 18.0 0.0 0.0038 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MscL PF01741.18 KEY73703.1 - 0.01 16.1 1.4 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL LYRIC PF15686.5 KEY73703.1 - 0.026 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Claudin_2 PF13903.6 KEY73703.1 - 0.04 13.7 9.6 0.22 11.3 9.8 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 KEY73703.1 - 0.047 13.5 10.8 0.023 14.5 4.3 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 KEY73703.1 - 0.076 13.9 6.5 0.14 13.0 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KEY73703.1 - 0.15 12.7 2.4 0.24 12.0 0.6 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.11 KEY73703.1 - 0.31 11.0 1.4 0.63 10.0 0.0 2.0 1 1 1 2 2 2 0 Protocadherin DHHC PF01529.20 KEY73703.1 - 0.8 9.8 4.6 0.17 12.0 1.0 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pilin_N PF07790.11 KEY73703.1 - 1.5 9.8 6.1 16 6.5 1.7 3.1 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal TMIE PF16038.5 KEY73703.1 - 2.6 8.0 6.7 1.8 8.4 1.4 2.5 2 0 0 2 2 2 0 TMIE protein DUF4381 PF14316.6 KEY73703.1 - 3.5 7.9 6.8 0.33 11.2 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) DUF5527 PF17665.1 KEY73703.1 - 3.9 7.0 8.3 0.13 11.8 0.3 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5527) DUF1772 PF08592.11 KEY73703.1 - 4.3 7.7 14.5 0.43 10.9 6.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) VIT1 PF01988.19 KEY73703.1 - 4.5 7.1 9.6 8 6.3 9.6 1.4 1 0 0 1 1 1 0 VIT family Med1 PF10744.9 KEY73705.1 - 3e-117 392.2 0.0 3.8e-117 391.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Glyco_hydro_16 PF00722.21 KEY73706.1 - 1.7e-06 27.6 0.1 1.7e-06 27.6 0.1 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 DLH PF01738.18 KEY73707.1 - 4.6e-27 95.0 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KEY73707.1 - 0.00079 19.4 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KEY73707.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY73707.1 - 0.019 14.4 0.0 0.77 9.2 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KEY73707.1 - 0.1 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Formyl_trans_N PF00551.19 KEY73708.1 - 8.6e-22 77.7 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KEY73708.1 - 2.1e-07 31.1 0.0 4.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain S-antigen PF05756.11 KEY73709.1 - 1.7 9.0 3.1 3.7 8.0 3.1 1.5 1 0 0 1 1 1 0 S-antigen protein DUF3405 PF11885.8 KEY73710.1 - 1.3e-190 634.4 5.7 1.7e-190 634.1 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.22 KEY73711.1 - 9.6e-22 77.0 14.2 3.4e-11 43.2 3.0 2.6 3 0 0 3 3 3 2 LIM domain NAD_binding_5 PF07994.12 KEY73712.1 - 9.2e-146 485.3 0.2 1.4e-145 484.7 0.2 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KEY73712.1 - 9.5e-45 151.3 0.5 3.7e-44 149.4 0.5 2.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase MRC1 PF09444.10 KEY73712.1 - 2.1e-43 148.4 18.9 2.1e-43 148.4 18.9 6.9 7 1 1 8 8 8 1 MRC1-like domain Asn_synthase PF00733.21 KEY73713.1 - 6.5e-93 312.2 0.0 6.8e-54 183.9 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase UQ_con PF00179.26 KEY73713.1 - 5.4e-45 152.5 0.0 9.5e-45 151.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GATase_7 PF13537.6 KEY73713.1 - 1.5e-36 125.0 0.0 2.3e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KEY73713.1 - 6.1e-28 97.7 0.0 1.3e-27 96.6 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KEY73713.1 - 3.5e-08 33.2 0.0 6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein Prok-E2_B PF14461.6 KEY73713.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B NAD_synthase PF02540.17 KEY73713.1 - 0.0017 17.6 0.0 0.0032 16.6 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Pex19 PF04614.12 KEY73714.1 - 5.9e-77 258.7 14.4 8.4e-77 258.2 14.4 1.2 1 0 0 1 1 1 1 Pex19 protein family DEC-1_N PF04625.13 KEY73714.1 - 0.0036 16.4 11.1 0.0055 15.8 11.1 1.3 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Asp-B-Hydro_N PF05279.11 KEY73714.1 - 0.02 15.0 0.4 0.02 15.0 0.4 2.3 2 1 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region KIX_2 PF16987.5 KEY73714.1 - 1.1 9.3 4.5 0.42 10.6 1.0 2.1 2 1 0 2 2 2 0 KIX domain FKBP_N PF01346.18 KEY73714.1 - 6.9 7.7 12.6 9.8 7.2 1.6 3.5 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ABC1 PF03109.16 KEY73716.1 - 2.8e-33 114.6 0.1 4.5e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 ABC1 family UCR_Fe-S_N PF10399.9 KEY73716.1 - 0.029 13.7 2.6 0.075 12.4 2.6 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Porin_3 PF01459.22 KEY73717.1 - 2.8e-65 220.5 7.7 2.6e-54 184.5 3.8 2.0 2 0 0 2 2 2 2 Eukaryotic porin DnaJ PF00226.31 KEY73718.1 - 6.9e-19 67.7 1.1 1.1e-18 67.1 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KEY73719.1 - 2.9e-34 118.3 0.1 8.6e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73719.1 - 5.9e-10 39.1 11.4 1e-09 38.3 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KEY73719.1 - 0.11 12.1 2.1 0.34 10.5 2.1 1.9 1 0 0 1 1 1 0 Trimerisation motif Stealth_CR4 PF17103.5 KEY73719.1 - 0.11 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 SET PF00856.28 KEY73720.1 - 0.00011 22.6 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.10 KEY73721.1 - 2.4e-34 118.3 0.0 7.3e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KEY73721.1 - 5.6e-17 61.9 0.0 2e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY73721.1 - 2.6e-06 27.1 0.1 0.00017 21.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEY73721.1 - 0.0048 16.4 0.3 2.9 7.4 0.1 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY73721.1 - 0.021 14.7 0.5 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KEY73721.1 - 0.021 14.9 0.9 0.25 11.4 0.2 2.7 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KEY73721.1 - 0.037 13.8 0.3 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF356 PF04009.12 KEY73721.1 - 0.1 12.9 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) ABC_tran PF00005.27 KEY73721.1 - 0.11 13.0 0.0 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 KEY73721.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KEY73721.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 KEY73721.1 - 0.18 10.7 2.0 0.69 8.8 0.0 2.6 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB F-box-like PF12937.7 KEY73722.1 - 1.7e-07 31.0 0.6 7.6e-07 28.9 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY73722.1 - 0.0049 16.7 0.9 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.6 KEY73722.1 - 0.0057 17.4 0.9 0.0057 17.4 0.9 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73722.1 - 0.0095 15.7 1.0 5 7.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73722.1 - 0.069 13.5 2.3 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73722.1 - 0.14 12.4 6.9 7.8 6.9 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73722.1 - 0.68 10.6 7.0 0.47 11.1 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 KEY73723.1 - 3.4e-12 46.7 0.0 5.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 KEY73724.1 - 2.1e-46 153.9 17.6 8.3e-06 25.4 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73724.1 - 1.4e-44 146.6 16.3 7.6e-05 22.5 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73724.1 - 2.3e-25 88.9 5.9 1.5e-06 28.8 0.1 6.8 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73724.1 - 6.6e-25 85.7 7.7 0.00019 21.6 0.0 9.3 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73724.1 - 2.3e-24 83.5 22.7 0.00048 20.1 0.0 10.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73724.1 - 2e-21 76.0 18.6 0.00011 22.4 0.8 8.1 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEY73724.1 - 3.8e-21 74.5 19.8 3.3e-05 23.5 0.0 9.0 7 1 2 9 9 8 4 TPR repeat TPR_19 PF14559.6 KEY73724.1 - 8.3e-16 58.3 18.0 0.0001 22.8 0.2 6.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73724.1 - 5.6e-14 51.6 14.4 0.00042 20.9 0.2 9.0 4 2 6 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEY73724.1 - 3.5e-13 49.5 6.9 0.00028 21.0 0.0 6.1 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73724.1 - 1.7e-08 33.9 17.9 0.66 10.1 0.2 9.1 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY73724.1 - 3.4e-08 33.3 2.4 1.7e-06 27.7 0.5 2.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 KEY73724.1 - 1.3e-06 28.1 16.5 0.72 9.8 0.6 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY73724.1 - 5.9e-06 26.4 11.3 0.13 12.5 0.0 5.4 2 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KEY73724.1 - 0.00011 21.5 8.6 0.11 11.7 2.3 4.1 2 1 3 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEY73724.1 - 0.00065 19.1 7.5 1.8 8.1 0.0 5.5 5 0 0 5 5 5 2 SHNi-TPR MAS20 PF02064.15 KEY73724.1 - 0.0015 18.7 8.8 0.016 15.3 0.2 4.4 4 1 1 5 5 5 1 MAS20 protein import receptor TPR_6 PF13174.6 KEY73724.1 - 0.0046 17.5 22.2 4.3 8.2 0.0 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 KEY73724.1 - 0.0085 15.1 0.2 0.0085 15.1 0.2 4.5 3 2 2 5 5 4 1 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 KEY73724.1 - 0.036 12.8 0.1 0.13 10.9 0.0 2.0 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Coatomer_E PF04733.14 KEY73724.1 - 0.045 13.2 5.6 0.88 8.9 0.0 3.6 3 1 0 3 3 3 0 Coatomer epsilon subunit MIT PF04212.18 KEY73724.1 - 0.23 11.6 19.2 42 4.3 0.8 6.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KEY73724.1 - 0.86 10.0 5.7 18 5.8 0.1 4.6 3 2 1 4 4 4 0 Bacterial transcriptional activator domain HemY_N PF07219.13 KEY73724.1 - 2 8.7 10.4 12 6.1 0.0 5.3 3 2 4 7 7 7 0 HemY protein N-terminus SPO22 PF08631.10 KEY73724.1 - 4.1 6.8 6.7 20 4.5 0.0 4.0 4 1 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like Sel1 PF08238.12 KEY73724.1 - 9 7.1 12.9 2.2 9.1 0.2 4.7 5 0 0 5 5 3 0 Sel1 repeat Syntaxin PF00804.25 KEY73725.1 - 8.8e-24 84.3 6.8 8.8e-24 84.3 6.8 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KEY73725.1 - 3.9e-11 42.8 1.1 6.3e-11 42.1 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KEY73725.1 - 0.00034 20.9 6.6 0.00034 20.9 6.6 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Tweety PF04906.13 KEY73725.1 - 0.058 12.0 3.1 2.7 6.5 0.4 2.3 2 0 0 2 2 2 0 Tweety Prominin PF05478.11 KEY73725.1 - 0.089 10.7 0.1 0.089 10.7 0.1 2.2 2 0 0 2 2 2 0 Prominin ETRAMP PF09716.10 KEY73725.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Bac_export_3 PF01313.19 KEY73725.1 - 0.14 12.1 0.7 0.25 11.3 0.7 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 CNOT11 PF10155.9 KEY73725.1 - 0.15 12.3 0.4 0.57 10.4 0.1 1.9 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Use1 PF09753.9 KEY73725.1 - 0.2 11.4 13.4 1 9.1 13.4 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 Allexi_40kDa PF05549.11 KEY73725.1 - 0.31 10.5 9.3 0.089 12.3 2.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Muted PF14942.6 KEY73725.1 - 0.59 10.5 11.9 0.11 12.9 4.4 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fib_alpha PF08702.10 KEY73725.1 - 2.5 8.3 14.9 4.8 7.4 5.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IZUMO PF15005.6 KEY73725.1 - 3 8.4 4.4 14 6.2 0.1 2.5 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated MCU PF04678.13 KEY73725.1 - 5.2 7.1 7.4 57 3.8 7.4 2.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter TMCO5 PF14992.6 KEY73725.1 - 5.7 6.4 10.2 42 3.6 9.9 2.4 1 1 0 1 1 1 0 TMCO5 family DUF4094 PF13334.6 KEY73725.1 - 8.5 6.9 9.0 15 6.1 1.0 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) Brix PF04427.18 KEY73726.1 - 3.2e-31 109.0 0.0 4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 KEY73727.1 - 9.6e-70 233.4 3.5 9.6e-70 233.4 3.5 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KEY73727.1 - 1.9e-59 200.6 0.0 5.3e-59 199.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KEY73727.1 - 2.8e-55 187.9 3.4 3.5e-31 108.9 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KEY73727.1 - 2.4e-32 111.0 0.0 4.8e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KEY73727.1 - 5.9e-14 52.2 0.6 7.5e-13 48.6 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEY73727.1 - 1.4e-10 41.7 0.2 4.1e-10 40.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KEY73727.1 - 4.7e-06 26.7 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KEY73727.1 - 0.00019 21.1 0.1 0.0047 16.5 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KEY73727.1 - 0.00022 21.1 0.6 0.53 10.0 0.0 3.0 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KEY73727.1 - 0.00024 20.4 0.5 0.2 10.8 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 KEY73727.1 - 0.00024 21.0 0.0 0.00072 19.5 0.0 1.9 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 KEY73727.1 - 0.00026 20.8 0.4 0.00054 19.8 0.3 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KEY73727.1 - 0.00083 18.7 0.6 0.008 15.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KEY73727.1 - 0.0017 17.7 0.0 0.007 15.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_10 PF12846.7 KEY73727.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.16 KEY73727.1 - 0.03 13.8 0.1 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_S13_N PF08069.12 KEY73727.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain T2SSE PF00437.20 KEY73727.1 - 0.087 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KEY73727.1 - 0.089 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KEY73727.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KEY73727.1 - 0.11 12.8 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain Glyco_hydro_47 PF01532.20 KEY73728.1 - 1.4e-162 541.8 0.0 1.6e-162 541.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GDPD PF03009.17 KEY73729.1 - 6e-30 104.8 0.0 3.1e-29 102.5 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KEY73729.1 - 0.072 13.6 1.8 0.92 10.1 0.2 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.18 KEY73730.1 - 1.2e-25 90.1 0.0 2.9e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.13 KEY73731.1 - 3.2e-71 238.6 0.8 3.7e-71 238.4 0.8 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KEY73731.1 - 0.00086 19.7 0.2 0.0033 17.8 0.2 1.9 1 1 0 1 1 1 1 Rubrerythrin PLDc PF00614.22 KEY73732.1 - 8.8e-17 60.5 0.5 8.7e-08 32.0 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KEY73732.1 - 1.8e-13 50.5 0.1 1.8e-07 31.1 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KEY73732.1 - 7.4e-07 29.2 0.1 6.1e-06 26.2 0.0 2.6 3 1 0 3 3 3 1 PX domain PH_2 PF08458.10 KEY73732.1 - 0.051 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region ERG4_ERG24 PF01222.17 KEY73733.1 - 7.9e-134 446.6 21.3 9.1e-134 446.4 21.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.21 KEY73734.1 - 2.4e-34 117.5 35.3 2.1e-21 76.0 14.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 KEY73735.1 - 9.1e-25 86.2 0.1 1.2e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KEY73735.1 - 9.4e-05 22.5 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KEY73735.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Syja_N PF02383.18 KEY73736.1 - 1.7e-91 306.9 0.0 2.5e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KEY73736.1 - 3.7e-39 133.0 0.0 6.7e-39 132.2 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Methyltransf_34 PF11312.8 KEY73737.1 - 3e-110 368.2 0.0 3.6e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase POTRA PF07244.15 KEY73737.1 - 0.13 12.8 0.1 0.29 11.7 0.1 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat Transketolase_N PF00456.21 KEY73738.1 - 2.1e-159 529.9 0.0 2.7e-159 529.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEY73738.1 - 2.7e-43 147.7 0.0 4.4e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEY73738.1 - 6.3e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KEY73738.1 - 0.00063 19.0 0.0 0.00096 18.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KEY73738.1 - 0.0013 18.6 1.6 0.02 14.7 0.8 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pas_Saposin PF09016.10 KEY73738.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Pas factor saposin fold Glycos_transf_2 PF00535.26 KEY73738.1 - 0.17 11.7 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF5308 PF17233.2 KEY73739.1 - 1.5e-50 171.6 16.2 2.4e-48 164.5 16.2 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Btz PF09405.10 KEY73740.1 - 3.9e-27 95.1 2.7 7.7e-27 94.1 2.7 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding N_BRCA1_IG PF16158.5 KEY73741.1 - 2.1e-32 111.8 0.0 6.8e-32 110.2 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KEY73741.1 - 5.4e-20 70.9 51.0 3.2e-06 26.9 7.7 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KEY73741.1 - 0.0092 16.3 46.6 0.084 13.2 4.4 4.5 4 0 0 4 4 4 3 C1 domain Tubulin PF00091.25 KEY73742.1 - 3.4e-57 193.9 0.0 9.7e-57 192.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEY73742.1 - 2.1e-44 150.7 0.1 3.6e-44 150.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Ran_BP1 PF00638.18 KEY73742.1 - 3.3e-09 37.0 0.0 8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KEY73742.1 - 6.7e-05 23.7 48.3 0.00028 21.7 21.0 11.0 3 1 6 10 10 10 4 Nucleoporin FG repeat region UPF0160 PF03690.13 KEY73743.1 - 8e-133 443.0 0.0 9.1e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.17 KEY73744.1 - 1.3e-26 92.5 0.0 2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region GCS PF03074.16 KEY73745.1 - 5.8e-180 598.4 0.0 7e-180 598.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Prefoldin_3 PF13758.6 KEY73747.1 - 0.036 14.1 3.3 0.036 14.1 3.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit LMBR1 PF04791.16 KEY73747.1 - 0.24 10.3 11.1 0.29 10.0 11.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Smac_DIABLO PF09057.10 KEY73747.1 - 0.55 9.6 9.6 0.14 11.5 6.3 1.7 1 1 1 2 2 2 0 Second Mitochondria-derived Activator of Caspases DUF1664 PF07889.12 KEY73747.1 - 2.6 8.1 8.7 0.51 10.4 1.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KEY73747.1 - 3 8.3 28.4 56 4.2 28.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FUSC PF04632.12 KEY73747.1 - 3.4 6.1 7.5 3.8 5.9 6.8 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family VSG_B PF13206.6 KEY73747.1 - 4.5 6.4 15.1 7.6 5.7 15.1 1.5 1 1 0 1 1 1 0 Trypanosomal VSG domain FliD_N PF02465.18 KEY73747.1 - 6.5 7.5 9.3 0.76 10.5 3.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3723 PF12520.8 KEY73750.1 - 1.9e-15 56.6 0.0 2.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Spc7 PF08317.11 KEY73750.1 - 0.011 14.7 10.9 0.015 14.2 10.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LAGLIDADG_3 PF14528.6 KEY73750.1 - 0.062 13.6 0.4 0.98 9.8 0.1 2.2 2 0 0 2 2 2 0 LAGLIDADG-like domain Atg14 PF10186.9 KEY73750.1 - 0.33 10.0 6.7 0.59 9.2 6.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KIP1 PF07765.12 KEY73750.1 - 0.59 10.3 5.3 6.4 7.0 3.2 2.4 2 0 0 2 2 2 0 KIP1-like protein RNA_polI_A14 PF08203.11 KEY73750.1 - 1 10.1 3.7 2.6 8.8 3.7 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 HET PF06985.11 KEY73751.1 - 3.1e-11 43.8 4.4 1.6e-10 41.5 3.9 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 KEY73755.1 - 3.5e-07 30.8 0.7 1e-05 26.0 1.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEY73755.1 - 1.3e-05 25.2 0.5 0.007 16.3 0.1 3.0 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KEY73755.1 - 2.1e-05 24.8 0.6 0.0013 19.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KEY73755.1 - 0.00035 19.8 0.0 0.00098 18.4 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KEY73755.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEY73755.1 - 0.027 15.0 4.5 0.13 12.7 4.5 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KEY73755.1 - 0.028 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KEY73755.1 - 0.044 14.3 0.1 0.13 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter DUF676 PF05057.14 KEY73755.1 - 0.065 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.22 KEY73755.1 - 0.069 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KEY73755.1 - 0.095 13.1 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DHR10 PF18595.1 KEY73755.1 - 0.15 12.1 10.7 0.048 13.7 1.0 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain AAA_29 PF13555.6 KEY73755.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Leu_zip PF15294.6 KEY73755.1 - 0.19 11.2 4.4 0.32 10.5 4.4 1.2 1 0 0 1 1 1 0 Leucine zipper TPR_4 PF07721.14 KEY73755.1 - 3.7 8.4 5.2 0.85 10.4 0.4 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73755.1 - 7.3 7.7 6.2 29 5.8 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Imm3 PF14425.6 KEY73756.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 Immunity protein Imm3 Pox_MCEL PF03291.16 KEY73756.1 - 0.047 12.8 0.1 0.058 12.5 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme PhoU PF01895.19 KEY73757.1 - 0.1 13.1 0.3 0.21 12.0 0.3 1.6 1 0 0 1 1 1 0 PhoU domain Cas_Cmr5 PF09701.10 KEY73757.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) adh_short PF00106.25 KEY73758.1 - 2e-24 86.2 0.5 3e-24 85.6 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.8 KEY73758.1 - 2.7e-20 72.6 2.5 3.6e-20 72.1 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KEY73758.1 - 1.4e-14 54.2 0.4 2.3e-14 53.5 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DDE_Tnp_1_7 PF13843.6 KEY73758.1 - 2.6e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 Epimerase PF01370.21 KEY73758.1 - 7.9e-06 25.5 0.1 0.0011 18.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY73758.1 - 0.0014 18.6 0.9 0.0034 17.3 0.9 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY73758.1 - 0.0019 18.2 0.2 0.0047 16.8 0.1 1.8 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 KEY73758.1 - 0.0042 16.7 0.2 0.0073 15.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KEY73758.1 - 0.0087 16.3 0.2 0.016 15.4 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KEY73758.1 - 0.046 13.1 0.3 0.95 8.8 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase TPR_10 PF13374.6 KEY73759.1 - 1.9e-22 78.4 1.0 1.5e-08 34.2 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73759.1 - 1.6e-17 63.5 0.3 3.7e-06 27.1 0.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEY73759.1 - 2.2e-13 50.0 0.0 3.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.6 KEY73759.1 - 4.3e-07 29.5 0.1 0.13 12.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KEY73759.1 - 0.00015 21.7 0.0 0.00039 20.4 0.0 1.7 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KEY73759.1 - 0.0014 17.9 0.0 0.089 12.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_16 PF13432.6 KEY73759.1 - 0.0058 17.2 0.0 1.4 9.6 0.1 3.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73759.1 - 0.016 16.0 0.3 52 5.0 0.1 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73759.1 - 0.11 12.7 1.7 11 6.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73759.1 - 0.13 12.8 0.1 7 7.3 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY73759.1 - 0.71 10.7 4.3 79 4.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.22 KEY73760.1 - 1.1e-08 34.3 0.0 8.9e-06 24.7 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.23 KEY73761.1 - 4.4e-42 144.6 10.9 5.5e-42 144.3 10.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEY73761.1 - 7e-34 117.3 0.0 1.4e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEY73761.1 - 2.4e-05 23.9 0.0 0.014 14.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEY73761.1 - 9e-05 22.9 0.0 0.00021 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KEY73761.1 - 0.00068 19.5 0.1 0.0096 15.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEY73761.1 - 0.0018 18.6 0.0 0.008 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEY73761.1 - 0.0031 17.5 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY73761.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KEY73761.1 - 0.0087 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KEY73761.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY73761.1 - 0.014 15.1 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KEY73761.1 - 0.022 14.9 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEY73761.1 - 0.025 13.9 0.0 0.11 11.8 0.0 2.0 3 0 0 3 3 2 0 Zeta toxin ATP-synt_ab PF00006.25 KEY73761.1 - 0.03 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KEY73761.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KEY73761.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KEY73761.1 - 0.032 13.8 0.0 0.097 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEY73761.1 - 0.041 14.3 0.0 0.23 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 KEY73761.1 - 0.046 12.7 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 KEY73761.1 - 0.058 13.9 0.0 0.18 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEY73761.1 - 0.062 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain GPAT_N PF14829.6 KEY73761.1 - 0.07 13.1 0.0 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal NACHT PF05729.12 KEY73761.1 - 0.1 12.5 0.2 0.47 10.4 0.0 2.1 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 KEY73761.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KEY73761.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY73761.1 - 0.17 12.3 0.0 0.69 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF4470 PF14737.6 KEY73762.1 - 1.7e-27 95.5 0.7 2.5e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEY73762.1 - 2.4e-08 33.9 12.0 4.6e-08 33.0 12.0 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KEY73762.1 - 0.51 10.3 7.9 1.2 9.1 7.9 1.6 1 0 0 1 1 1 0 HIT zinc finger UDPGT PF00201.18 KEY73763.1 - 9.1e-10 37.9 0.0 4.5e-07 29.0 0.0 2.5 3 0 0 3 3 3 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KEY73763.1 - 0.0079 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KEY73763.1 - 0.053 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KEY73763.1 - 0.058 13.4 0.5 0.17 11.8 0.1 2.0 2 1 0 2 2 2 0 Glycosyltransferase Family 4 MFS_1 PF07690.16 KEY73765.1 - 3.8e-38 131.3 35.1 3.8e-38 131.3 35.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73765.1 - 2.6e-06 26.6 24.7 7.5e-06 25.1 15.3 3.4 2 1 2 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 KEY73765.1 - 0.0002 19.8 2.3 0.0002 19.8 2.3 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KEY73765.1 - 0.0029 16.2 17.1 0.0029 16.2 17.1 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein ABC2_membrane_5 PF13346.6 KEY73765.1 - 0.0094 15.5 5.3 0.0094 15.5 5.3 3.4 2 1 2 4 4 4 1 ABC-2 family transporter protein Fungal_trans PF04082.18 KEY73766.1 - 6.9e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73766.1 - 0.57 10.3 12.0 0.06 13.5 3.3 2.7 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 KEY73767.1 - 7.7e-115 383.6 0.0 9.7e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KEY73767.1 - 6.4e-06 25.4 0.1 2e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEY73767.1 - 0.00024 20.3 0.1 0.00039 19.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KEY73767.1 - 0.0028 17.1 0.3 0.0042 16.5 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KEY73767.1 - 0.0054 16.1 0.0 2.1 7.6 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEY73767.1 - 0.011 15.2 0.1 1.3 8.4 0.0 2.5 1 1 1 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 KEY73767.1 - 0.042 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase STI1 PF17830.1 KEY73767.1 - 0.18 11.7 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 STI1 domain FAD_binding_4 PF01565.23 KEY73768.1 - 1e-24 86.8 3.8 2.5e-24 85.6 3.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY73768.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Presenilin PF01080.17 KEY73769.1 - 1.1 8.0 3.1 1.4 7.6 3.1 1.2 1 0 0 1 1 1 0 Presenilin MSA_2 PF00985.17 KEY73769.1 - 4.9 7.5 10.9 10 6.4 10.9 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Pyr_redox_2 PF07992.14 KEY73770.1 - 5e-38 131.0 0.6 6.4e-38 130.6 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY73770.1 - 3.7e-11 43.4 1.0 2.1e-09 37.8 0.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY73770.1 - 4.6e-07 29.4 0.0 1.1e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY73770.1 - 1.2e-06 28.4 4.0 0.0088 15.7 0.2 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY73770.1 - 2.7e-05 23.4 0.4 0.042 12.9 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.6 KEY73770.1 - 6.1e-05 22.3 0.0 0.00021 20.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KEY73770.1 - 8.1e-05 21.6 0.5 0.89 8.3 0.2 3.1 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KEY73770.1 - 0.0002 21.4 2.0 1.3 9.0 0.0 4.0 3 1 0 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KEY73770.1 - 0.0012 17.7 0.2 0.056 12.1 0.1 3.3 4 1 1 5 5 5 1 HI0933-like protein Thi4 PF01946.17 KEY73770.1 - 0.0036 16.6 0.2 0.33 10.1 0.2 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KEY73770.1 - 0.0078 16.4 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEY73770.1 - 3.1 6.8 7.3 3.1 6.8 1.5 3.2 3 1 0 4 4 4 0 Glucose inhibited division protein A Acetyltransf_7 PF13508.7 KEY73771.1 - 5.7e-07 29.9 0.0 9e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY73771.1 - 7.1e-07 29.5 0.0 1.2e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY73771.1 - 3.5e-06 27.0 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fringe PF02434.16 KEY73772.1 - 2e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KEY73772.1 - 0.002 18.0 0.7 0.0061 16.5 0.7 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KEY73772.1 - 0.0086 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 PAN domain CorA PF01544.18 KEY73773.1 - 4.3e-06 26.3 0.1 1.7e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein TssN PF17555.2 KEY73773.1 - 0.015 14.7 0.2 0.025 14.0 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2207 PF09972.9 KEY73773.1 - 0.027 13.3 0.1 0.06 12.1 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Zot PF05707.12 KEY73773.1 - 0.091 12.4 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TFIIE_beta PF02186.15 KEY73773.1 - 0.096 13.0 0.3 0.37 11.1 0.3 2.0 1 0 0 1 1 1 0 TFIIE beta subunit core domain ADH_N_2 PF16884.5 KEY73774.1 - 1e-26 92.9 0.0 2.5e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY73774.1 - 3.2e-22 78.9 0.1 4.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY73774.1 - 1e-09 39.5 0.1 2.4e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KEY73774.1 - 0.11 12.8 0.2 8.3 6.7 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Sugar_tr PF00083.24 KEY73775.1 - 7.2e-92 308.6 22.0 8.7e-92 308.3 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73775.1 - 6.6e-25 87.8 39.8 2.6e-22 79.2 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY73775.1 - 1.2e-06 27.3 2.6 2e-06 26.6 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KEY73775.1 - 0.00053 19.0 0.3 0.00098 18.1 0.3 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM RTA1 PF04479.13 KEY73777.1 - 5.3e-63 212.4 15.1 8.4e-63 211.7 15.1 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3007 PF11460.8 KEY73777.1 - 0.13 12.5 0.2 0.5 10.7 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Metallophos PF00149.28 KEY73779.1 - 4.5e-08 33.8 1.1 6.6e-08 33.3 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY73779.1 - 8.6e-08 32.6 0.1 4.4e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain SOXp PF12336.8 KEY73779.1 - 0.072 14.2 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 SOX transcription factor PNP_UDP_1 PF01048.20 KEY73780.1 - 3.3e-15 56.0 0.8 6.7e-15 55.0 0.2 1.9 2 1 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.12 KEY73780.1 - 0.00018 21.5 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 KEY73780.1 - 0.053 13.4 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KEY73780.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEY73780.1 - 0.16 12.4 0.1 0.49 10.8 0.1 1.9 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KEY73780.1 - 0.2 12.2 0.0 0.64 10.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 KEY73780.1 - 0.54 9.4 2.3 3 7.0 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain adh_short PF00106.25 KEY73781.1 - 6.2e-15 55.2 0.0 2.7e-13 49.8 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73781.1 - 7e-06 25.8 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3140 PF11338.8 KEY73783.1 - 2.3e-35 120.9 1.4 2.3e-35 120.9 1.4 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KEY73783.1 - 1.1e-14 54.3 1.5 1.1e-14 54.3 1.5 2.9 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain TFIIF_alpha PF05793.12 KEY73783.1 - 5.4 5.5 52.5 6.9 5.1 52.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) dCMP_cyt_deam_1 PF00383.23 KEY73784.1 - 9.7e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEY73784.1 - 7.4e-08 32.2 0.0 8.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KEY73784.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KEY73784.1 - 0.042 13.9 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 KEY73784.1 - 0.071 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KEY73784.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 zf-LITAF-like PF10601.9 KEY73785.1 - 5e-12 45.9 10.0 7.4e-12 45.4 10.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.6 KEY73785.1 - 0.062 13.8 0.7 0.46 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Ank_2 PF12796.7 KEY73786.1 - 1.8e-22 79.7 1.9 1.1e-10 41.9 1.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY73786.1 - 8.5e-17 61.0 7.5 5.3e-06 26.6 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73786.1 - 1.5e-16 58.8 2.9 0.00015 21.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KEY73786.1 - 3e-15 55.9 9.2 4.5e-06 26.9 0.2 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KEY73786.1 - 2.4e-14 53.5 5.8 2.6e-05 24.7 0.4 4.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) zf-CCCH_6 PF18585.1 KEY73786.1 - 0.076 12.9 0.1 0.58 10.1 0.0 2.3 1 1 1 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Sugar_tr PF00083.24 KEY73789.1 - 5.2e-87 292.6 25.5 6.5e-87 292.3 25.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73789.1 - 6.8e-12 45.0 42.0 1.6e-08 33.9 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KEY73790.1 - 6.2e-52 175.7 0.0 4.2e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KEY73790.1 - 2e-49 167.9 35.1 2.7e-30 105.4 6.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 KEY73790.1 - 8.8e-16 58.6 2.8 0.0048 16.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEY73790.1 - 1.1e-09 39.1 1.3 0.0036 17.8 0.3 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KEY73790.1 - 3.2e-09 36.6 0.1 0.00087 18.8 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEY73790.1 - 6.7e-09 36.1 0.6 0.0077 16.5 0.1 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEY73790.1 - 6.9e-08 32.6 0.1 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEY73790.1 - 1.2e-07 32.2 0.1 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KEY73790.1 - 1.5e-07 31.5 0.0 0.0066 16.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 KEY73790.1 - 3.3e-07 29.9 1.5 0.01 15.6 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KEY73790.1 - 2.1e-06 27.6 0.0 0.0045 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEY73790.1 - 1.6e-05 24.8 0.1 0.7 9.5 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KEY73790.1 - 1.8e-05 25.1 0.4 0.065 13.5 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KEY73790.1 - 7.6e-05 22.4 0.1 0.27 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KEY73790.1 - 9e-05 21.7 0.2 0.061 12.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 KEY73790.1 - 9.4e-05 22.8 0.2 0.071 13.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEY73790.1 - 0.00011 21.9 2.1 0.2 11.3 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KEY73790.1 - 0.00019 21.8 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KEY73790.1 - 0.00027 21.0 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KEY73790.1 - 0.00039 20.4 0.2 2.3 8.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEY73790.1 - 0.00058 20.0 0.1 0.37 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KEY73790.1 - 0.00067 19.4 0.2 1.5 8.5 0.0 2.6 3 0 0 3 3 2 2 AAA domain ATP_bind_1 PF03029.17 KEY73790.1 - 0.0012 18.7 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KEY73790.1 - 0.0017 18.3 0.8 0.31 10.9 0.1 3.6 4 0 0 4 4 4 1 NTPase Zeta_toxin PF06414.12 KEY73790.1 - 0.0028 17.0 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KEY73790.1 - 0.0041 17.2 3.3 0.41 10.7 0.3 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEY73790.1 - 0.005 16.2 0.4 0.92 8.8 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.9 KEY73790.1 - 0.0052 16.1 0.1 0.5 9.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KEY73790.1 - 0.0056 17.2 0.5 4.5 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 KEY73790.1 - 0.006 16.8 0.8 2.8 8.2 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KEY73790.1 - 0.011 16.0 0.2 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KEY73790.1 - 0.011 16.1 0.3 6.4 7.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KEY73790.1 - 0.012 15.6 0.4 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 KEY73790.1 - 0.012 15.3 0.3 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KEY73790.1 - 0.015 15.7 0.3 0.26 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KEY73790.1 - 0.02 14.2 0.2 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 KEY73790.1 - 0.026 14.0 2.4 1.2 8.5 0.1 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein G-alpha PF00503.20 KEY73790.1 - 0.046 12.9 0.4 20 4.2 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit SRP54 PF00448.22 KEY73790.1 - 0.054 13.1 0.6 9.5 5.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KEY73790.1 - 0.057 12.9 0.2 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 KEY73790.1 - 0.066 12.0 0.1 0.34 9.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 KEY73790.1 - 0.077 12.2 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DnaB_C PF03796.15 KEY73790.1 - 0.11 11.8 0.2 11 5.2 0.0 2.8 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KEY73790.1 - 0.11 12.5 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 KEY73790.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 CDR ABC transporter SRPRB PF09439.10 KEY73790.1 - 0.13 11.6 0.3 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 KEY73790.1 - 0.19 11.4 0.1 21 4.8 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KEY73790.1 - 0.2 11.4 0.4 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Dynamin_N PF00350.23 KEY73790.1 - 0.34 10.9 7.1 5.6 7.0 0.2 3.6 4 0 0 4 4 3 0 Dynamin family ABC2_membrane_3 PF12698.7 KEY73790.1 - 2.5 7.1 29.7 2.4 7.2 11.7 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF87 PF01935.17 KEY73790.1 - 9.7 6.2 8.6 2.6 8.1 0.4 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Amidohydro_1 PF01979.20 KEY73791.1 - 1.8e-25 90.0 0.0 1.1e-24 87.4 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEY73791.1 - 2e-13 50.7 0.1 7.1e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family polyprenyl_synt PF00348.17 KEY73792.1 - 3.3e-75 252.4 0.0 5.6e-75 251.7 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KEY73792.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.8 KEY73793.1 - 1.5e-41 141.7 0.0 2.6e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0220 PF05255.11 KEY73793.1 - 0.01 15.4 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) zf-C2H2_3 PF13878.6 KEY73794.1 - 1.8e-07 30.8 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF1179 PF06678.11 KEY73794.1 - 0.089 12.8 4.4 0.24 11.4 4.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Lipocalin_5 PF13924.6 KEY73795.1 - 4.5e-29 101.1 0.0 5.1e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain NACHT PF05729.12 KEY73796.1 - 2.4e-09 37.3 0.1 7.2e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73796.1 - 1.4e-06 28.8 0.7 4.9e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY73796.1 - 1.6e-05 25.2 0.0 5.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEY73796.1 - 0.018 15.0 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KEY73796.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEY73796.1 - 0.03 14.8 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEY73796.1 - 0.049 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain dNK PF01712.19 KEY73796.1 - 0.061 13.2 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase ATPase_2 PF01637.18 KEY73796.1 - 0.24 11.3 0.6 2 8.3 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DLH PF01738.18 KEY73797.1 - 6.4e-14 52.0 0.0 1e-13 51.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KEY73797.1 - 0.00029 21.5 2.7 0.00056 20.6 2.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family EBP PF05241.12 KEY73798.1 - 2e-55 187.0 9.8 2.5e-55 186.7 9.8 1.1 1 0 0 1 1 1 1 Emopamil binding protein CysG_dimeriser PF10414.9 KEY73801.1 - 0.095 12.4 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Cellulase PF00150.18 KEY73803.1 - 1.9e-49 168.6 0.7 2.6e-49 168.2 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KEY73803.1 - 1.8e-12 46.9 7.7 1.8e-12 46.9 7.7 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain MGC-24 PF05283.11 KEY73803.1 - 0.86 10.1 11.7 1.5 9.3 11.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AlaDh_PNT_N PF05222.15 KEY73804.1 - 4.9e-20 72.2 0.0 7.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KEY73804.1 - 0.039 13.2 0.0 0.092 12.0 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RcsF PF16358.5 KEY73804.1 - 0.23 11.5 0.0 0.47 10.5 0.0 1.4 1 0 0 1 1 1 0 RcsF lipoprotein MFS_1 PF07690.16 KEY73805.1 - 3.3e-30 105.2 29.4 3.3e-30 105.2 29.4 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MAP17 PF15807.5 KEY73805.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2614 PF11023.8 KEY73805.1 - 4.7 7.3 5.4 0.71 10.0 0.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain Glyco_hydro_18 PF00704.28 KEY73806.1 - 8.5e-90 301.6 0.0 9.6e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KEY73806.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Nop PF01798.18 KEY73807.1 - 3.2e-73 246.0 0.9 5.5e-73 245.2 0.9 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEY73807.1 - 9.9e-18 64.3 0.0 3.8e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain YL1 PF05764.13 KEY73807.1 - 0.45 10.6 19.4 0.89 9.6 19.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KEY73807.1 - 3.2 5.9 12.9 5.1 5.3 12.9 1.3 1 0 0 1 1 1 0 CDC45-like protein GRA6 PF05084.13 KEY73807.1 - 4.2 7.3 5.8 9.1 6.2 5.8 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Fungal_trans_2 PF11951.8 KEY73808.1 - 1.5e-05 24.0 0.2 0.00021 20.3 0.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1929 PF09118.11 KEY73809.1 - 2.3e-21 75.9 0.0 5.1e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KEY73809.1 - 1.2e-17 63.5 7.2 1e-05 25.6 0.0 5.1 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KEY73809.1 - 5.6e-12 45.0 2.5 0.00029 20.4 0.3 4.5 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KEY73809.1 - 7.1e-11 41.6 2.6 0.029 14.3 0.2 5.3 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KEY73809.1 - 1.1e-08 34.9 7.8 0.0047 16.9 0.0 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KEY73809.1 - 2.3e-05 23.7 0.0 0.053 12.7 0.0 2.6 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 KEY73809.1 - 0.00094 19.4 0.0 0.00094 19.4 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain PAN_1 PF00024.26 KEY73809.1 - 0.0067 16.4 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 PAN domain ubiquitin PF00240.23 KEY73810.1 - 4.6e-34 116.0 1.0 7.8e-34 115.3 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KEY73810.1 - 3e-26 91.3 1.9 3e-26 91.3 1.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KEY73810.1 - 2.3e-16 59.4 0.7 4.8e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEY73810.1 - 2.1e-05 24.9 0.5 0.00013 22.4 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEY73810.1 - 0.00071 19.7 0.8 0.0015 18.6 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KEY73810.1 - 0.0042 17.4 0.9 0.0075 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KEY73810.1 - 0.0053 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KEY73810.1 - 0.012 16.1 0.9 0.017 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KEY73810.1 - 0.016 15.2 1.0 5.8 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 KEY73811.1 - 2.5e-52 175.8 9.6 2.9e-52 175.6 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KEY73811.1 - 0.025 14.5 0.4 0.061 13.3 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KEY73811.1 - 0.24 11.2 2.2 0.28 11.0 2.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) GFA PF04828.14 KEY73812.1 - 8.8e-18 64.4 0.8 2.5e-09 37.4 0.0 3.3 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme ADH_zinc_N PF00107.26 KEY73812.1 - 9.6e-10 38.5 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY73812.1 - 8.1e-07 28.9 0.0 2.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY73812.1 - 0.0071 17.4 0.0 0.013 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LVIVD PF08309.11 KEY73813.1 - 0.058 12.7 0.1 4.7 6.6 0.0 3.1 3 0 0 3 3 3 0 LVIVD repeat TBD PF12845.7 KEY73814.1 - 0.031 14.2 1.0 0.071 13.0 1.0 1.5 1 0 0 1 1 1 0 TBD domain p450 PF00067.22 KEY73815.1 - 5.6e-25 88.0 0.0 6.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_cc PF11790.8 KEY73816.1 - 2.1e-55 187.9 0.0 2.4e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core AMP-binding PF00501.28 KEY73817.1 - 0 1732.4 0.0 5.5e-80 269.0 0.0 7.2 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.20 KEY73817.1 - 3.6e-290 962.1 5.6 1.6e-46 159.0 0.2 8.7 7 2 1 8 8 8 8 Condensation domain PP-binding PF00550.25 KEY73817.1 - 7.1e-97 317.8 11.0 1.2e-13 51.2 0.0 9.1 9 0 0 9 9 9 8 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KEY73817.1 - 2.2e-39 135.2 0.0 3.9e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KEY73817.1 - 1.7e-11 44.0 0.0 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KEY73817.1 - 5.1e-08 33.8 0.0 1.6 9.7 0.0 6.5 8 0 0 8 8 8 2 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KEY73818.1 - 3.2e-20 72.4 0.3 8.8e-19 67.7 0.1 2.7 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73818.1 - 3.3e-11 43.2 0.1 1.2e-10 41.4 0.0 1.9 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73818.1 - 8.5e-10 38.8 0.1 1.3e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY73818.1 - 0.0094 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY73818.1 - 0.063 13.2 0.5 0.12 12.3 0.5 1.4 1 1 0 1 1 1 0 NAD(P)H-binding rve_2 PF13333.6 KEY73819.1 - 0.053 13.7 0.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain SMC_N PF02463.19 KEY73821.1 - 4.1e-73 245.4 18.7 4.5e-72 242.0 18.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEY73821.1 - 7.5e-25 87.5 0.0 3.8e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEY73821.1 - 1.8e-12 47.7 0.6 4.7e-05 23.3 0.3 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEY73821.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KEY73821.1 - 0.00088 19.4 15.7 0.00088 19.4 15.7 8.3 3 2 7 10 10 8 2 Tropomyosin like ERM PF00769.19 KEY73821.1 - 0.0023 17.8 12.3 0.0023 17.8 12.3 5.4 2 2 3 5 5 5 1 Ezrin/radixin/moesin family GAS PF13851.6 KEY73821.1 - 0.0028 17.0 8.8 0.0028 17.0 8.8 7.7 3 2 5 8 8 8 2 Growth-arrest specific micro-tubule binding AAA_23 PF13476.6 KEY73821.1 - 0.0074 16.8 28.8 0.0074 16.8 28.8 6.9 3 2 1 4 4 2 1 AAA domain AT_hook PF02178.19 KEY73821.1 - 0.091 12.7 4.5 0.42 10.7 4.5 2.2 1 0 0 1 1 1 0 AT hook motif LPP PF04728.13 KEY73821.1 - 0.25 11.8 0.0 0.25 11.8 0.0 7.4 6 2 2 8 8 8 0 Lipoprotein leucine-zipper ABC_tran PF00005.27 KEY73821.1 - 1.8 9.1 0.0 1.8 9.1 0.0 6.5 4 2 0 4 4 2 0 ABC transporter ELYS PF13934.6 KEY73822.1 - 1.3e-62 211.6 3.0 1.6e-62 211.4 3.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly p450 PF00067.22 KEY73823.1 - 9.2e-37 126.9 0.0 4.2e-24 85.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Mpv17_PMP22 PF04117.12 KEY73824.1 - 9e-19 67.5 2.2 9e-19 67.5 2.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family CENP-Q PF13094.6 KEY73825.1 - 0.014 15.6 1.6 0.014 15.6 1.6 5.2 4 3 1 6 6 5 0 CENP-Q, a CENPA-CAD centromere complex subunit HIP1_clath_bdg PF16515.5 KEY73825.1 - 0.091 13.4 40.6 0.032 14.9 8.4 6.5 5 2 1 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Relaxase PF03432.14 KEY73825.1 - 0.29 10.7 3.8 0.98 9.0 3.8 1.9 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Tropomyosin_1 PF12718.7 KEY73825.1 - 0.39 10.9 28.3 0.36 11.0 1.0 4.4 3 1 1 4 4 4 0 Tropomyosin like HSBP1 PF06825.12 KEY73825.1 - 1.3 9.0 7.5 4.8 7.1 0.4 3.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 G-gamma PF00631.22 KEY73825.1 - 1.9 8.5 8.4 40 4.3 0.0 4.2 4 0 0 4 4 4 0 GGL domain Sipho_Gp157 PF05565.11 KEY73825.1 - 2 8.4 18.3 0.11 12.5 3.7 4.0 4 1 1 5 5 5 0 Siphovirus Gp157 CagE_TrbE_VirB PF03135.14 KEY73825.1 - 6.8 6.7 5.7 1.2 9.2 1.5 1.8 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system APG6_N PF17675.1 KEY73825.1 - 7.9 7.0 41.6 6.1 7.4 4.4 5.4 4 2 1 5 5 5 0 Apg6 coiled-coil region AAA_13 PF13166.6 KEY73825.1 - 8.5 4.9 17.1 0.11 11.1 0.6 3.3 3 1 1 4 4 4 0 AAA domain Phage_GP20 PF06810.11 KEY73825.1 - 8.7 6.1 26.3 3.7 7.3 0.8 4.7 4 1 2 6 6 6 0 Phage minor structural protein GP20 CCSMST1 PF15013.6 KEY73827.1 - 0.15 12.2 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 CCSMST1 family DUF4231 PF14015.6 KEY73827.1 - 0.21 12.1 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Polbeta PF18765.1 KEY73828.1 - 1.3e-10 41.2 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KEY73828.1 - 6.4e-08 32.8 0.0 2.6e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Fungal_trans PF04082.18 KEY73830.1 - 2.1e-05 23.7 0.0 3.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73830.1 - 0.55 10.4 4.9 1.8 8.8 4.9 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 KEY73831.1 - 9.9e-38 130.2 2.4 1.6e-37 129.5 2.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KEY73831.1 - 1.4e-19 70.0 1.3 4e-18 65.3 0.2 3.3 3 1 0 3 3 3 1 Carbohydrate binding domain X2 Mrx7 PF10906.8 KEY73831.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 MIOREX complex component 7 DUF1479 PF07350.12 KEY73832.1 - 1.5e-154 514.8 0.0 1.7e-154 514.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KEY73832.1 - 0.00079 19.7 0.2 0.27 11.5 0.2 2.5 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Cnn_1N PF07989.11 KEY73833.1 - 4.2e-22 78.1 7.6 4.2e-22 78.1 7.6 12.1 9 1 2 12 12 12 1 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KEY73833.1 - 8e-08 32.5 13.5 8e-08 32.5 13.5 13.1 13 2 1 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Spectrin PF00435.21 KEY73833.1 - 0.0051 17.3 0.1 0.0051 17.3 0.1 9.9 5 2 3 10 10 10 1 Spectrin repeat NPV_P10 PF05531.12 KEY73833.1 - 0.02 15.3 19.7 0.04 14.4 0.0 6.7 6 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Vip3A_N PF12495.8 KEY73833.1 - 0.027 14.4 3.1 10 6.0 0.3 3.6 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal DUF2935 PF11155.8 KEY73833.1 - 9.1 6.6 20.2 20 5.5 0.2 5.3 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) MARVEL PF01284.23 KEY73835.1 - 4.5e-06 26.8 14.3 1.2e-05 25.4 13.9 1.8 1 1 1 2 2 2 2 Membrane-associating domain Cadherin_C_2 PF16492.5 KEY73835.1 - 1 10.2 3.1 36 5.2 0.0 2.4 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal Virul_fac_BrkB PF03631.15 KEY73835.1 - 1.6 8.2 23.0 1.1 8.9 16.2 2.1 2 0 0 2 2 2 0 Virulence factor BrkB Arginase PF00491.21 KEY73836.1 - 2.4e-73 247.1 0.1 3e-73 246.7 0.1 1.0 1 0 0 1 1 1 1 Arginase family Glyco_transf_90 PF05686.12 KEY73837.1 - 3.6e-14 52.5 2.5 3.6e-11 42.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 AIM3 PF17096.5 KEY73837.1 - 3.4 8.7 7.5 11 7.0 7.5 1.9 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RrnaAD PF00398.20 KEY73838.1 - 1.3e-05 24.4 0.0 3.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AAA PF00004.29 KEY73839.1 - 2.5e-41 141.2 0.0 6.9e-41 139.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KEY73839.1 - 1.9e-25 88.7 0.0 9e-25 86.5 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KEY73839.1 - 9.3e-17 60.9 4.6 9.3e-17 60.9 4.6 2.2 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KEY73839.1 - 2.7e-08 33.5 0.1 2.4e-07 30.4 0.0 2.6 3 0 0 3 3 2 1 AAA+ lid domain RuvB_N PF05496.12 KEY73839.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY73839.1 - 1.1e-05 25.8 0.0 0.0013 19.1 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY73839.1 - 4.5e-05 23.8 0.1 0.02 15.1 0.0 3.1 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KEY73839.1 - 5e-05 23.6 0.0 0.0098 16.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KEY73839.1 - 5.2e-05 22.6 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KEY73839.1 - 5.8e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KEY73839.1 - 6.9e-05 22.9 0.0 0.00023 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KEY73839.1 - 9e-05 22.5 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEY73839.1 - 0.00022 20.5 0.0 0.00091 18.5 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEY73839.1 - 0.0003 20.6 1.7 0.0061 16.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEY73839.1 - 0.00097 19.7 0.0 0.0028 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain PrkA PF06798.12 KEY73839.1 - 0.0015 18.2 0.1 0.0074 15.9 0.1 2.0 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_2 PF07724.14 KEY73839.1 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KEY73839.1 - 0.0034 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEY73839.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEY73839.1 - 0.019 14.5 0.1 0.48 10.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEY73839.1 - 0.029 13.7 0.0 0.084 12.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEY73839.1 - 0.035 13.6 0.1 0.15 11.5 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KEY73839.1 - 0.065 12.7 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein TPR_12 PF13424.6 KEY73839.1 - 0.077 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.12 KEY73839.1 - 0.094 12.6 0.0 0.71 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KEY73839.1 - 0.097 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 KEY73839.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.6 KEY73839.1 - 0.12 12.2 0.1 13 5.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Prefoldin_2 PF01920.20 KEY73840.1 - 8.6e-18 64.3 12.2 1.1e-17 63.9 12.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KEY73840.1 - 0.00019 21.6 4.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF3584 PF12128.8 KEY73840.1 - 0.00064 17.4 5.0 0.00071 17.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fez1 PF06818.15 KEY73840.1 - 0.0021 18.6 8.3 0.0063 17.0 0.6 2.1 2 0 0 2 2 2 1 Fez1 Spc7 PF08317.11 KEY73840.1 - 0.0027 16.6 10.4 0.0034 16.3 10.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SKA2 PF16740.5 KEY73840.1 - 0.0034 17.1 4.1 0.0085 15.9 1.8 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 GAS PF13851.6 KEY73840.1 - 0.013 14.9 6.7 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KEY73840.1 - 0.015 15.4 9.8 0.48 10.5 5.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 KEY73840.1 - 0.018 15.5 9.8 0.49 10.8 0.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Siah-Interact_N PF09032.11 KEY73840.1 - 0.019 15.2 9.3 0.98 9.8 3.0 2.3 1 1 1 2 2 2 0 Siah interacting protein, N terminal Occludin_ELL PF07303.13 KEY73840.1 - 0.029 15.1 4.7 0.072 13.8 1.8 2.0 2 0 0 2 2 2 0 Occludin homology domain PHM7_cyt PF14703.6 KEY73840.1 - 0.03 14.5 3.1 0.059 13.6 3.1 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter LPP PF04728.13 KEY73840.1 - 0.044 14.2 7.7 0.53 10.7 0.3 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper End3 PF12761.7 KEY73840.1 - 0.059 13.5 9.9 0.076 13.2 9.9 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 KEY73840.1 - 0.07 13.7 7.5 1 10.0 0.1 2.4 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 KEY73840.1 - 0.076 13.4 4.5 4.9 7.6 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.11 KEY73840.1 - 0.08 12.8 4.6 0.17 11.7 4.6 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin PF02996.17 KEY73840.1 - 0.083 12.8 10.4 40 4.1 10.4 2.4 1 1 0 1 1 1 0 Prefoldin subunit Sas10_Utp3 PF04000.15 KEY73840.1 - 0.086 13.5 2.6 2.7 8.7 0.7 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF5082 PF16888.5 KEY73840.1 - 0.091 13.0 10.2 0.66 10.3 10.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4201 PF13870.6 KEY73840.1 - 0.1 12.3 7.3 0.89 9.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CSN5_C PF18323.1 KEY73840.1 - 0.1 13.5 3.9 1 10.3 0.2 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain FapA PF03961.13 KEY73840.1 - 0.11 11.1 6.0 0.15 10.6 6.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nup88 PF10168.9 KEY73840.1 - 0.11 10.3 4.9 0.13 10.0 4.9 1.0 1 0 0 1 1 1 0 Nuclear pore component Curto_V3 PF07436.11 KEY73840.1 - 0.12 12.8 0.4 0.31 11.5 0.1 1.7 2 0 0 2 2 2 0 Curtovirus V3 protein DUF4407 PF14362.6 KEY73840.1 - 0.13 11.6 7.3 0.21 10.9 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LidA_Long_CC PF18641.1 KEY73840.1 - 0.14 12.3 5.7 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 LidA long coiled-coil domain IFT57 PF10498.9 KEY73840.1 - 0.15 11.0 8.2 2.6 6.9 3.5 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DASH_Hsk3 PF08227.11 KEY73840.1 - 0.17 12.3 2.6 26 5.3 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like MIP-T3_C PF17749.1 KEY73840.1 - 0.2 11.6 8.6 0.16 11.9 1.4 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region GreA_GreB_N PF03449.15 KEY73840.1 - 0.21 11.7 5.1 3.4 7.9 1.5 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF4279 PF14106.6 KEY73840.1 - 0.23 11.6 2.2 0.31 11.2 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) FlxA PF14282.6 KEY73840.1 - 0.27 11.3 11.2 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 FlxA-like protein EzrA PF06160.12 KEY73840.1 - 0.28 9.3 9.1 1.7 6.7 0.3 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KEY73840.1 - 0.29 11.3 7.6 3.2 7.9 7.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KEY73840.1 - 0.3 11.6 5.6 4.5 7.8 0.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 KEY73840.1 - 0.3 11.4 5.1 2.7 8.4 0.4 3.0 2 2 1 3 3 3 0 Uncharacterized conserved protein DUF4140 PF13600.6 KEY73840.1 - 0.34 11.4 10.3 3.7 8.0 0.3 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dam1 PF08653.10 KEY73840.1 - 0.37 10.6 0.9 17 5.3 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 KEY73840.1 - 0.38 10.8 3.2 5.1 7.1 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 KEY73840.1 - 0.41 10.7 12.7 0.25 11.4 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding COG6 PF06419.11 KEY73840.1 - 0.46 8.6 7.3 0.54 8.4 2.0 2.0 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 Com_YlbF PF06133.11 KEY73840.1 - 0.52 10.9 11.1 0.54 10.9 6.0 2.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA ABC_tran_CTD PF16326.5 KEY73840.1 - 0.53 10.6 13.6 0.39 11.0 0.7 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain ERM PF00769.19 KEY73840.1 - 0.58 9.9 9.7 0.86 9.4 9.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HrpB7 PF09486.10 KEY73840.1 - 0.65 10.4 7.5 4 7.8 7.5 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.14 KEY73840.1 - 0.71 10.2 17.3 2.6 8.4 10.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KEY73840.1 - 0.71 10.4 16.3 1.3 9.6 8.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region YgaB PF14182.6 KEY73840.1 - 0.96 9.9 9.0 2.2 8.7 0.9 2.4 2 1 0 2 2 2 0 YgaB-like protein DivIC PF04977.15 KEY73840.1 - 1.3 8.9 14.4 0.46 10.3 0.6 3.0 2 1 0 2 2 2 0 Septum formation initiator SKA1 PF07160.12 KEY73840.1 - 1.5 8.6 8.6 2.9 7.7 0.4 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2968 PF11180.8 KEY73840.1 - 1.5 8.4 13.8 4 7.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4164 PF13747.6 KEY73840.1 - 1.7 9.0 9.2 3.1 8.1 3.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF724 PF05266.14 KEY73840.1 - 1.8 8.4 9.4 1.2e+02 2.4 9.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KEY73840.1 - 2 8.9 15.9 21 5.6 15.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.8 KEY73840.1 - 2 8.5 11.9 1.4 9.0 1.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 KEY73840.1 - 2.1 8.3 11.9 6.2 6.7 6.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain UPF0242 PF06785.11 KEY73840.1 - 2.3 8.3 15.0 6.4 6.8 15.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 KEY73840.1 - 2.3 8.3 7.2 3.9 7.6 3.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BST2 PF16716.5 KEY73840.1 - 3.7 8.2 10.8 5.3 7.7 0.3 2.6 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 XhlA PF10779.9 KEY73840.1 - 3.9 7.7 6.8 3.5 7.9 0.8 2.5 2 2 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 KEY73840.1 - 4 6.6 5.7 6.1 6.0 5.7 1.3 1 1 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 KEY73840.1 - 4.6 7.8 17.7 9.8 6.7 9.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB FAM76 PF16046.5 KEY73840.1 - 5.2 6.3 6.3 11 5.2 6.3 1.5 1 1 0 1 1 1 0 FAM76 protein Golgin_A5 PF09787.9 KEY73840.1 - 5.8 6.3 11.8 28 4.1 6.8 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2203 PF09969.9 KEY73840.1 - 7 7.4 7.2 69 4.2 7.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Swi5 PF07061.11 KEY73840.1 - 8.4 6.6 9.6 16 5.7 0.5 2.4 1 1 1 2 2 2 0 Swi5 YabA PF06156.13 KEY73840.1 - 9 7.0 8.6 18 6.1 3.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA JAB PF01398.21 KEY73841.1 - 3.5e-13 49.5 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KEY73841.1 - 4.5e-09 36.5 0.0 8.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KEY73841.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Glyco_hydro_61 PF03443.14 KEY73842.1 - 8.9e-56 189.1 0.0 1.1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DDE_1 PF03184.19 KEY73843.1 - 8e-31 107.0 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DivIC PF04977.15 KEY73843.1 - 0.024 14.4 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator FAD-SLDH PF12318.8 KEY73843.1 - 0.05 13.7 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase NB-ARC PF00931.22 KEY73844.1 - 7.5e-14 51.5 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KEY73844.1 - 4.4e-08 33.3 5.2 3.8e-07 30.3 0.5 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KEY73844.1 - 8.1e-06 26.2 0.0 2.8e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.6 KEY73844.1 - 2.4e-05 24.0 0.4 0.15 12.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF676 PF05057.14 KEY73844.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.6 KEY73844.1 - 0.00039 20.2 2.3 1.6 8.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KEY73844.1 - 0.002 18.5 0.4 0.016 15.6 0.4 2.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEY73844.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 KEY73844.1 - 0.035 14.3 0.1 22 5.6 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73844.1 - 0.042 14.0 0.6 69 3.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY73844.1 - 0.061 13.6 0.2 2.1 8.6 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KEY73844.1 - 0.093 13.3 1.5 1.1 9.8 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEY73844.1 - 0.12 12.7 2.0 4.2 7.8 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF960 PF06124.11 KEY73844.1 - 0.16 12.6 0.0 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) DUF3488 PF11992.8 KEY73845.1 - 0.034 13.1 6.7 0.051 12.5 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DPM3 PF08285.11 KEY73845.1 - 1.1 9.5 7.2 0.46 10.7 3.6 2.1 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SUR7 PF06687.12 KEY73845.1 - 3.5 7.2 13.3 4.6 6.8 13.3 1.2 1 0 0 1 1 1 0 SUR7/PalI family Abhydrolase_1 PF00561.20 KEY73846.1 - 5.2e-18 65.6 0.0 3.3e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KEY73846.1 - 4.6e-07 29.9 0.2 5.2e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 TAP-like protein BTB_3 PF16017.5 KEY73846.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TPR_10 PF13374.6 KEY73847.1 - 1.6e-25 88.2 0.1 1e-13 50.6 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73847.1 - 4e-20 71.9 0.1 2.2e-11 43.9 0.0 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73847.1 - 4.4e-05 23.2 0.1 0.00083 19.2 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73847.1 - 0.00024 20.9 0.5 0.084 13.0 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73847.1 - 0.0017 18.1 1.0 0.15 11.9 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73847.1 - 0.0044 17.1 0.4 0.36 11.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 KEY73847.1 - 0.009 16.0 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY73847.1 - 0.016 15.7 0.0 0.06 14.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73847.1 - 0.04 14.4 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73847.1 - 0.082 13.6 0.0 0.32 11.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73847.1 - 0.24 11.9 1.5 5.9 7.5 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.14 KEY73848.1 - 5.1e-47 160.5 0.0 8.3e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY73848.1 - 2.8e-11 43.2 13.9 9.5e-11 41.5 13.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEY73848.1 - 1.5 9.2 9.2 3.7 7.9 9.2 1.8 1 0 0 1 1 1 0 Toxin 7 DDE_Tnp_1_7 PF13843.6 KEY73849.1 - 4.8e-13 49.2 0.0 1.8e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 HTH_30 PF13556.6 KEY73851.1 - 0.77 9.6 3.8 0.79 9.6 0.4 2.8 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain DNA_ligase_A_N PF04675.14 KEY73852.1 - 1.4e-18 67.8 0.0 2.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KEY73852.1 - 3.4e-11 43.2 0.0 2.5e-07 30.5 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Antimicrobial_2 PF08023.12 KEY73852.1 - 0.041 14.4 1.8 0.1 13.2 1.8 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Tannase PF07519.11 KEY73855.1 - 6.6e-95 318.7 1.9 7.7e-95 318.5 1.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEY73855.1 - 9.2e-07 28.5 0.2 0.0043 16.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEY73855.1 - 0.036 13.3 0.0 0.099 11.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Period_C PF12114.8 KEY73855.1 - 0.097 12.2 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Glyco_transf_28 PF03033.20 KEY73856.1 - 8e-14 51.9 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Zn_clus PF00172.18 KEY73857.1 - 3.4e-09 36.7 10.5 5.6e-09 36.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KEY73857.1 - 0.27 11.6 7.2 0.062 13.6 3.2 2.0 2 0 0 2 2 2 0 Opy2 protein Defensin_4 PF07936.12 KEY73858.1 - 0.016 15.1 2.4 0.069 13.0 0.3 2.4 2 1 0 2 2 2 0 Potassium-channel blocking toxin LysR_substrate PF03466.20 KEY73860.1 - 0.036 13.4 2.0 0.07 12.5 2.0 1.5 1 1 0 1 1 1 0 LysR substrate binding domain Zea_mays_MuDR PF05928.11 KEY73860.1 - 1.2 8.7 4.5 1.7 8.2 4.5 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) 2-Hacid_dh PF00389.30 KEY73861.1 - 0.056 13.1 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ank_2 PF12796.7 KEY73862.1 - 9.3e-92 301.7 52.2 3.5e-15 56.4 1.0 6.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 KEY73862.1 - 4.2e-50 166.1 45.0 0.0024 18.3 0.2 13.9 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.6 KEY73862.1 - 2.1e-44 149.3 24.8 3.9e-06 27.3 0.2 11.6 1 1 12 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73862.1 - 1.3e-39 129.6 22.2 0.027 15.0 0.0 14.1 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 KEY73862.1 - 1.2e-32 111.5 29.3 8.5e-05 22.8 0.7 11.6 1 1 12 13 13 13 12 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KEY73862.1 - 3.3e-08 33.1 0.1 7.7e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KEY73862.1 - 2.2e-07 31.0 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73862.1 - 5.5e-05 23.6 0.1 0.00031 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KEY73862.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KEY73862.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mem_trans PF03547.18 KEY73863.1 - 2e-19 69.3 6.9 9.4e-19 67.1 6.9 1.8 1 1 0 1 1 1 1 Membrane transport protein NapE PF06796.11 KEY73863.1 - 0.0037 16.8 4.1 2.7 7.6 0.0 3.0 2 0 0 2 2 2 2 Periplasmic nitrate reductase protein NapE DUF1290 PF06947.12 KEY73863.1 - 3 8.0 5.5 0.95 9.6 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1290) Fungal_trans PF04082.18 KEY73864.1 - 1.8e-06 27.2 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73864.1 - 0.00015 21.8 18.8 0.00029 20.9 18.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.17 KEY73865.1 - 4.1e-32 111.5 0.0 5.6e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEY73865.1 - 1.6e-15 56.8 0.3 3.4e-15 55.8 0.3 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEY73865.1 - 0.00058 19.6 0.0 0.0028 17.4 0.0 2.1 1 1 0 2 2 2 1 Peptidase family M20/M25/M40 adh_short PF00106.25 KEY73866.1 - 8.3e-38 129.8 0.0 1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73866.1 - 8.2e-22 77.9 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY73866.1 - 5e-06 26.2 0.0 8.3e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY73866.1 - 0.00031 20.7 0.1 0.00054 19.9 0.1 1.3 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KEY73866.1 - 0.00038 21.0 0.1 0.00038 21.0 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KEY73866.1 - 0.00043 19.5 0.0 0.00082 18.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEY73866.1 - 0.00089 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KEY73866.1 - 0.0082 16.0 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEY73866.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEY73866.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_6 PF12697.7 KEY73867.1 - 2.5e-06 28.3 0.9 4.9e-06 27.3 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY73867.1 - 0.0041 16.8 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.15 KEY73868.1 - 4.5e-45 152.5 0.9 4.5e-45 152.5 0.9 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KEY73868.1 - 2.9e-29 102.3 0.1 1.2e-27 97.0 0.0 2.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEY73868.1 - 7.2e-11 42.0 4.7 0.00042 20.0 0.8 3.9 3 1 0 3 3 3 2 Multicopper oxidase Mucin PF01456.17 KEY73868.1 - 0.19 11.7 12.3 0.19 11.7 10.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein adh_short PF00106.25 KEY73869.1 - 2.4e-17 63.1 0.2 1.3e-15 57.4 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73869.1 - 2.9e-07 30.3 0.2 9.6e-07 28.6 0.4 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73869.1 - 1.1e-06 28.7 0.3 1.8e-06 28.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_61 PF03443.14 KEY73871.1 - 1e-61 208.4 0.1 1.2e-61 208.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3237 PF11578.8 KEY73872.1 - 4.8e-28 97.9 0.5 6.7e-23 81.2 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Tyrosinase PF00264.20 KEY73873.1 - 4.1e-46 158.0 2.2 4.1e-46 158.0 2.2 4.2 2 1 0 2 2 2 1 Common central domain of tyrosinase UDPGT PF00201.18 KEY73874.1 - 3.4e-07 29.4 0.0 4.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KEY73874.1 - 0.001 19.1 0.0 0.0031 17.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KEY73874.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Carn_acyltransf PF00755.20 KEY73875.1 - 3.8e-94 316.4 0.0 5.1e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KEY73875.1 - 2.3e-70 237.1 0.1 2.3e-70 237.1 0.1 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY73875.1 - 9.2e-51 173.2 3.0 1.9e-50 172.2 3.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY73875.1 - 2.8e-49 167.5 0.1 1.3e-48 165.3 0.1 2.3 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEY73875.1 - 3.9e-47 160.9 0.0 3.3e-46 157.9 0.0 2.4 1 1 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY73875.1 - 1.8e-33 115.1 0.2 6.5e-33 113.3 0.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY73875.1 - 2e-16 60.4 0.0 4.9e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KEY73875.1 - 3.1e-15 57.4 0.0 1.3e-13 52.1 0.0 3.8 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY73875.1 - 2.5e-14 53.4 0.1 1.3e-13 51.1 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEY73875.1 - 2.5e-11 43.4 1.0 1.8e-09 37.4 0.1 3.5 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KEY73875.1 - 2.1e-06 27.7 0.0 1.8e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 KEY73875.1 - 8.6e-05 22.4 0.0 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEY73875.1 - 0.0033 17.7 0.1 0.0084 16.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEY73875.1 - 0.0061 17.3 0.0 0.039 14.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73875.1 - 0.014 16.1 0.0 0.12 13.1 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73875.1 - 0.036 13.9 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.23 KEY73875.1 - 0.067 12.5 4.8 0.046 13.1 0.5 2.2 2 0 0 2 2 2 0 Thiolase, N-terminal domain UDPGT PF00201.18 KEY73876.1 - 3.9e-09 35.8 0.0 1.4e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Acyl_transf_3 PF01757.22 KEY73877.1 - 2.6e-20 72.8 13.8 3.4e-20 72.4 13.8 1.2 1 0 0 1 1 1 1 Acyltransferase family Amidohydro_2 PF04909.14 KEY73878.1 - 3.3e-22 79.6 0.0 4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KEY73879.1 - 9.3e-78 262.0 0.0 1.2e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KEY73880.1 - 3.7e-61 207.1 0.0 4.9e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73880.1 - 5.1e-34 117.9 0.0 8.7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEY73880.1 - 1.5e-07 30.8 0.2 0.0014 17.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEY73880.1 - 4.9e-05 23.1 0.1 0.024 14.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY73880.1 - 6.8e-05 22.3 0.2 0.35 10.1 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY73880.1 - 8.1e-05 22.8 0.1 0.00023 21.3 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEY73880.1 - 0.0025 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEY73880.1 - 0.0075 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KEY73880.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KEY73880.1 - 0.075 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KEY73880.1 - 0.16 10.8 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KEY73880.1 - 0.23 10.7 0.3 0.57 9.4 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Methyltransf_25 PF13649.6 KEY73881.1 - 7.7e-16 58.6 0.0 4.1e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY73881.1 - 4.8e-14 52.8 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY73881.1 - 4.7e-11 43.3 0.0 8.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY73881.1 - 1.4e-10 41.1 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY73881.1 - 9.2e-09 35.3 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY73881.1 - 1.8e-07 30.9 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEY73881.1 - 3.1e-07 30.1 0.0 4.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KEY73881.1 - 2e-06 27.3 0.1 3.7e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KEY73881.1 - 3e-05 23.7 0.0 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 KEY73881.1 - 6e-05 22.7 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 KEY73881.1 - 9.1e-05 21.9 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KEY73881.1 - 0.00048 19.2 0.0 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 KEY73881.1 - 0.00083 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 KEY73881.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KEY73881.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 NNMT_PNMT_TEMT PF01234.17 KEY73881.1 - 0.0047 16.2 0.0 1.8 7.7 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Rsm22 PF09243.10 KEY73881.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PhzC-PhzF PF02567.16 KEY73882.1 - 4e-41 141.3 0.0 4.8e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cation_ATPase_C PF00689.21 KEY73883.1 - 0.0061 16.3 1.0 0.0061 16.3 1.0 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Peptidase_M56 PF05569.11 KEY73883.1 - 0.056 12.6 6.8 0.14 11.3 6.9 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF3290 PF11694.8 KEY73883.1 - 8.8 6.3 11.2 1.8 8.5 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) ADH_zinc_N_2 PF13602.6 KEY73885.1 - 7.5e-18 65.9 0.0 1.4e-17 64.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY73885.1 - 2.5e-12 46.9 0.0 4.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY73885.1 - 1.3e-06 28.2 0.5 5.6e-06 26.2 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DFP PF04127.15 KEY73885.1 - 0.04 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 KEY73885.1 - 0.096 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase BNR_4 PF15892.5 KEY73886.1 - 3.7e-71 239.7 9.4 4.9e-71 239.3 9.4 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member BNR_2 PF13088.6 KEY73886.1 - 0.00017 21.0 0.1 0.00026 20.4 0.1 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KEY73886.1 - 0.026 14.5 0.2 0.16 12.1 0.2 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat HET PF06985.11 KEY73887.1 - 3.4e-31 108.6 0.1 6.1e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KEY73888.1 - 0.0043 16.9 0.2 0.0043 16.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like Transp_cyt_pur PF02133.15 KEY73889.1 - 1.3e-69 235.1 43.8 1.5e-69 234.9 43.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_6 PF12697.7 KEY73890.1 - 2.7e-12 47.7 0.1 3.2e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY73890.1 - 3.6e-10 39.9 0.1 9.8e-08 31.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY73890.1 - 4.2e-09 36.0 0.0 1.4e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KEY73890.1 - 0.00038 20.4 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 KEY73890.1 - 0.031 13.6 0.1 0.18 11.1 0.1 1.9 2 0 0 2 2 2 0 Secretory lipase Bac_luciferase PF00296.20 KEY73891.1 - 2.3e-54 184.9 0.1 3.1e-54 184.5 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AtuA PF07287.11 KEY73892.1 - 8.9e-123 409.4 0.1 1.3e-122 409.0 0.1 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KEY73892.1 - 1.3e-25 89.9 0.1 2.2e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73892.1 - 0.00025 21.1 3.1 0.0006 19.9 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3145 PF11343.8 KEY73892.1 - 0.078 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Amidohydro_2 PF04909.14 KEY73894.1 - 2e-26 93.5 0.4 2.2e-26 93.3 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase Isochorismatase PF00857.20 KEY73896.1 - 7.1e-13 49.1 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family COesterase PF00135.28 KEY73897.1 - 2.1e-56 191.9 0.0 3.6e-56 191.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY73897.1 - 0.003 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEY73897.1 - 0.005 16.7 2.8 0.0058 16.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold MMR_HSR1 PF01926.23 KEY73898.1 - 5.3e-09 36.2 0.0 3.7e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEY73898.1 - 3.5e-05 23.2 0.4 8.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 KEY73898.1 - 0.0012 18.4 0.1 0.0087 15.6 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 KEY73898.1 - 0.0016 17.6 0.1 0.0033 16.6 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KEY73898.1 - 0.0049 16.9 9.5 0.11 12.5 0.0 3.4 2 2 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KEY73898.1 - 0.0057 16.6 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KEY73898.1 - 0.33 10.3 3.7 8.5 5.6 0.6 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KEY73899.1 - 9e-10 38.6 1.7 1.4e-09 38.0 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEY73899.1 - 8.3e-07 28.5 0.0 8.3e-07 28.5 0.0 2.9 2 1 1 3 3 3 1 AIG1 family RsgA_GTPase PF03193.16 KEY73899.1 - 0.0083 16.0 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KEY73899.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY73899.1 - 0.021 15.1 0.6 2 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1953 PF09196.10 KEY73899.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) FeoB_N PF02421.18 KEY73899.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B BshC PF10079.9 KEY73899.1 - 0.075 11.8 9.3 0.12 11.1 9.3 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF87 PF01935.17 KEY73899.1 - 0.093 12.8 0.1 0.093 12.8 0.1 2.6 2 1 0 2 2 1 0 Helicase HerA, central domain AAA_16 PF13191.6 KEY73899.1 - 0.15 12.4 1.3 0.84 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain HTH_Tnp_IS1 PF12759.7 KEY73899.1 - 0.16 11.6 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 InsA C-terminal domain AAA_18 PF13238.6 KEY73899.1 - 0.17 12.4 2.0 0.29 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KEY73899.1 - 0.17 11.9 17.5 0.38 10.8 0.0 4.3 2 2 1 3 3 2 0 Dynamin family WDCP PF15390.6 KEY73899.1 - 0.5 8.7 4.9 0.59 8.5 4.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ABC_tran PF00005.27 KEY73899.1 - 0.84 10.2 0.0 0.84 10.2 0.0 3.0 2 1 0 2 2 1 0 ABC transporter AAA_23 PF13476.6 KEY73899.1 - 2 8.8 0.0 2 8.8 0.0 2.5 2 1 0 2 2 1 0 AAA domain CREPT PF16566.5 KEY73899.1 - 4.4 7.5 13.6 0.45 10.7 0.2 2.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-H PF05837.12 KEY73899.1 - 5.9 7.4 17.6 2.1 8.8 5.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GTP_EFTU PF00009.27 KEY73899.1 - 6.4 6.3 6.9 2.9 7.4 0.3 3.1 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 KEY73900.1 - 3.3e-22 78.9 49.0 2.7e-11 43.0 25.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.20 KEY73900.1 - 5.3e-05 23.0 0.2 5.3e-05 23.0 0.2 2.7 3 2 0 3 3 3 1 Haemolysin-III related TRI12 PF06609.13 KEY73900.1 - 0.14 10.5 24.5 0.87 7.9 24.5 2.2 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.7 KEY73901.1 - 4.7e-19 69.9 0.6 5.8e-19 69.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY73901.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Phage_holin_Dp1 PF16938.5 KEY73901.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative phage holin Dp-1 Abhydrolase_4 PF08386.10 KEY73904.1 - 2.3e-21 75.8 0.0 8.7e-21 74.0 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY73904.1 - 1.9e-13 50.7 0.0 6.2e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold K_oxygenase PF13434.6 KEY73905.1 - 0.00014 21.2 0.0 0.0054 15.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) ARL2_Bind_BART PF11527.8 KEY73905.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART FMO-like PF00743.19 KEY73905.1 - 0.042 12.3 0.4 0.098 11.1 0.1 1.7 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DDE_Tnp_1_7 PF13843.6 KEY73909.1 - 4.3e-25 88.8 0.0 4.5e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Pectate_lyase PF03211.13 KEY73911.1 - 3.9e-84 281.3 2.3 4.5e-84 281.1 2.3 1.0 1 0 0 1 1 1 1 Pectate lyase Ndc1_Nup PF09531.10 KEY73912.1 - 0.33 9.6 4.1 0.35 9.5 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TAF4 PF05236.14 KEY73912.1 - 0.95 9.2 11.2 1.3 8.7 11.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family p450 PF00067.22 KEY73915.1 - 2.2e-73 247.6 0.0 2.5e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec61_beta PF03911.16 KEY73915.1 - 2.1 8.4 3.6 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Sec61beta family Sugar_tr PF00083.24 KEY73917.1 - 1e-120 403.7 25.8 1.2e-120 403.5 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY73917.1 - 6e-24 84.6 34.9 8.6e-22 77.5 20.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.19 KEY73918.1 - 1.4e-22 80.1 18.8 1.4e-22 80.1 18.8 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEY73918.1 - 9e-10 38.6 0.0 0.00016 21.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KEY73918.1 - 2.5e-06 27.7 0.0 0.004 17.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.16 KEY73919.1 - 5.4e-35 121.0 37.8 5.4e-35 121.0 37.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Dysbindin PF04440.16 KEY73919.1 - 0.2 11.8 0.8 0.33 11.1 0.8 1.2 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF5455 PF17537.2 KEY73919.1 - 0.3 11.5 2.3 0.47 10.9 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5455) GFA PF04828.14 KEY73920.1 - 4e-14 52.7 4.4 2.5e-11 43.8 4.4 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldo_ket_red PF00248.21 KEY73921.1 - 7.1e-39 133.8 0.0 8.7e-37 126.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Exonuc_VII_S PF02609.16 KEY73922.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit zf-C2H2_4 PF13894.6 KEY73922.1 - 0.21 12.5 5.8 0.22 12.4 0.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY73922.1 - 0.28 11.7 5.5 0.4 11.2 2.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_12 PF13424.6 KEY73924.1 - 3.8e-24 84.8 1.0 5.8e-18 65.0 0.5 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY73924.1 - 2.8e-21 74.7 12.8 5.5e-11 42.0 0.1 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 KEY73924.1 - 8.1e-10 38.3 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 KEY73924.1 - 1.6e-05 24.3 3.9 0.00013 21.3 3.9 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KEY73924.1 - 0.00017 22.0 0.4 0.0014 19.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.6 KEY73924.1 - 0.0022 17.9 1.2 2.7 8.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73924.1 - 0.0051 16.6 6.4 0.15 12.0 0.8 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY73924.1 - 0.0052 16.2 0.7 0.0052 16.2 0.7 1.7 2 0 0 2 2 2 1 MalT-like TPR region NACHT PF05729.12 KEY73924.1 - 0.0062 16.5 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain TPR_8 PF13181.6 KEY73924.1 - 0.0068 16.5 3.1 1.8 9.0 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73924.1 - 0.0084 16.4 0.3 1.6 9.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4919 PF16266.5 KEY73924.1 - 0.02 14.8 1.0 0.069 13.1 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) AAA_22 PF13401.6 KEY73924.1 - 0.026 14.8 0.1 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_4 PF07721.14 KEY73924.1 - 0.17 12.6 0.5 24 5.9 0.0 3.6 4 1 0 4 4 3 0 Tetratricopeptide repeat Ras PF00071.22 KEY73925.1 - 6.4e-48 162.4 0.0 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KEY73925.1 - 4.9e-29 100.7 3.9 1.7e-11 44.5 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY73925.1 - 3.2e-17 62.6 4.5 1.2e-06 28.9 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KEY73925.1 - 1.1e-16 60.5 12.2 0.00081 19.7 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Roc PF08477.13 KEY73925.1 - 1.8e-15 57.2 0.0 8.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 KEY73925.1 - 3.8e-15 55.8 13.4 0.00055 20.2 0.1 6.4 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY73925.1 - 1.7e-14 52.5 4.1 0.12 13.0 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Hydrolase_4 PF12146.8 KEY73925.1 - 0.065 12.5 0.1 0.57 9.4 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DIOX_N PF14226.6 KEY73926.1 - 1.5e-20 74.1 0.0 3.9e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEY73926.1 - 5.6e-11 42.8 0.0 9.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KEY73927.1 - 1.1e-25 90.3 27.1 1.1e-25 90.3 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5336 PF17270.2 KEY73927.1 - 0.044 13.4 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) COesterase PF00135.28 KEY73928.1 - 2.3e-88 297.3 0.0 2.9e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY73928.1 - 5.2e-06 26.5 0.1 2.1e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.25 KEY73929.1 - 2.4e-08 33.6 0.2 6.1e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY73929.1 - 9e-07 29.0 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY73929.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_8 PF06259.12 KEY73929.1 - 0.063 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase HET PF06985.11 KEY73931.1 - 2.6e-12 47.3 5.6 7.4e-10 39.3 0.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) YpsA PF06908.11 KEY73931.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Zn_clus PF00172.18 KEY73933.1 - 2.5e-08 33.9 8.6 4e-08 33.3 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rtf2 PF04641.12 KEY73934.1 - 1.3e-48 165.7 5.5 3.7e-48 164.2 5.5 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KEY73934.1 - 1.9e-05 24.4 0.5 0.00011 22.0 0.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEY73934.1 - 0.0011 19.2 0.1 0.0028 17.9 0.1 1.6 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KEY73934.1 - 0.0018 18.2 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEY73934.1 - 0.0036 17.3 0.7 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEY73934.1 - 0.0037 17.1 0.4 0.0069 16.2 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEY73934.1 - 0.01 15.6 1.5 0.051 13.3 0.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger Zn-ribbon_8 PF09723.10 KEY73934.1 - 0.014 15.5 1.3 0.036 14.2 1.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KEY73934.1 - 0.028 14.3 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 KEY73934.1 - 0.077 13.1 3.9 0.72 10.0 0.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 KEY73934.1 - 0.099 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PIEZO PF15917.5 KEY73934.1 - 0.11 12.0 4.1 0.16 11.5 4.1 1.2 1 0 0 1 1 1 0 Piezo PPL5 PF18168.1 KEY73934.1 - 0.12 11.7 5.6 0.17 11.1 5.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 WLM PF08325.10 KEY73934.1 - 0.23 11.5 4.7 0.36 10.9 4.7 1.2 1 0 0 1 1 1 0 WLM domain UFD1 PF03152.14 KEY73937.1 - 8.7e-29 100.2 0.0 3.4e-13 49.4 0.0 4.0 4 0 0 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KEY73937.1 - 4e-08 33.4 0.1 4e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_9 PF16293.5 KEY73937.1 - 0.47 10.3 3.0 1 9.2 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) IATP PF04568.12 KEY73938.1 - 0.32 11.4 4.8 0.44 11.0 0.7 2.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-C3HC4_3 PF13920.6 KEY73938.1 - 8 6.4 12.0 1.4 8.9 4.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RhgB_N PF09284.10 KEY73939.1 - 1.3e-98 329.6 1.7 1.8e-98 329.1 0.5 1.7 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KEY73939.1 - 2.3e-39 134.9 0.0 4.8e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KEY73939.1 - 5.7e-24 83.7 4.4 2.6e-23 81.6 4.4 2.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KEY73939.1 - 0.00015 21.9 2.7 0.00015 21.9 2.7 3.9 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain Acylphosphatase PF00708.18 KEY73939.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Glyco_hydro_71 PF03659.14 KEY73940.1 - 1.4e-122 409.2 0.3 1.6e-122 409.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ank_4 PF13637.6 KEY73941.1 - 3.5e-60 199.6 9.3 1.4e-12 47.8 0.1 9.0 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY73941.1 - 3.7e-59 197.3 2.7 2.3e-12 47.3 0.0 6.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KEY73941.1 - 5.4e-48 159.4 1.0 0.00014 22.1 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KEY73941.1 - 4.4e-45 146.4 7.7 0.00021 21.4 0.1 10.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KEY73941.1 - 1.9e-39 133.2 12.0 1.3e-08 34.9 0.5 6.8 3 2 4 7 7 7 7 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KEY73941.1 - 1.2e-13 50.9 0.0 2.7e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KEY73941.1 - 6e-07 29.5 0.0 2.3e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73941.1 - 2e-05 25.1 0.4 0.00011 22.6 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KEY73941.1 - 0.017 15.6 0.0 0.053 14.0 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 KEY73941.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEY73941.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3157 PF11355.8 KEY73941.1 - 0.35 10.5 7.8 18 4.9 0.1 4.3 1 1 0 3 3 3 0 Protein of unknown function (DUF3157) Arf PF00025.21 KEY73943.1 - 0.00011 21.7 0.1 0.0071 15.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY73943.1 - 0.0002 20.9 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY73943.1 - 0.057 13.3 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KEY73943.1 - 0.064 12.6 0.1 0.15 11.4 0.1 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DDE_Tnp_1_7 PF13843.6 KEY73949.1 - 1e-09 38.2 0.0 2.9e-08 33.4 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 Ank_2 PF12796.7 KEY73950.1 - 2.5e-31 108.1 16.3 5e-14 52.7 1.8 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY73950.1 - 2.9e-15 54.8 3.2 0.56 10.9 0.1 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KEY73950.1 - 6.2e-15 55.4 0.8 0.00019 21.9 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY73950.1 - 2.6e-14 52.9 9.8 0.1 13.1 0.0 6.9 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KEY73950.1 - 1.8e-13 50.4 4.5 0.00035 20.8 0.2 6.1 2 1 4 6 6 6 4 Ankyrin repeats (many copies) NACHT PF05729.12 KEY73950.1 - 1.3e-09 38.2 0.1 2.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY73950.1 - 4.1e-07 30.5 0.2 5.3e-06 26.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 KEY73950.1 - 5.6e-06 25.8 0.4 1.6e-05 24.3 0.4 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KEY73950.1 - 0.00095 19.5 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEY73950.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KEY73950.1 - 0.014 15.5 0.1 0.48 10.4 0.1 2.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEY73950.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KEY73950.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4766 PF15973.5 KEY73950.1 - 0.43 11.2 5.7 36 5.0 5.7 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) GEN1_C PF18380.1 KEY73951.1 - 0.045 14.6 1.5 0.066 14.1 0.1 1.8 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain HET PF06985.11 KEY73952.1 - 4.1e-30 105.0 0.0 6.8e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pro_CA PF00484.19 KEY73953.1 - 0.00028 21.2 0.0 0.0078 16.5 0.0 2.1 1 1 0 1 1 1 1 Carbonic anhydrase NmrA PF05368.13 KEY73954.1 - 1.8e-18 67.0 0.0 3e-18 66.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY73954.1 - 5.2e-09 36.2 0.0 8.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY73954.1 - 0.0054 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain HET PF06985.11 KEY73955.1 - 0.0005 20.5 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KEY73956.1 - 9.3e-15 54.3 3.1 1.8e-12 46.8 3.1 2.9 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KEY73957.1 - 1.6e-31 109.3 0.0 2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73957.1 - 2.2e-20 73.2 0.0 2.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73957.1 - 2.3e-07 30.9 0.0 3.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY73957.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.18 KEY73958.1 - 5.1e-13 48.7 0.1 8.2e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Questin_oxidase PF14027.6 KEY73959.1 - 2.1e-37 129.5 0.2 6.2e-37 127.9 0.2 1.7 1 1 0 1 1 1 1 Questin oxidase-like DUF3098 PF11297.8 KEY73959.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF5504 PF17608.2 KEY73959.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5504) MerR PF00376.23 KEY73962.1 - 0.042 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein tRNA-synt_2 PF00152.20 KEY73968.1 - 1.6e-76 257.4 0.0 2.8e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Fungal_trans PF04082.18 KEY73970.1 - 4.7e-10 39.0 0.2 9.7e-10 37.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY73970.1 - 3.3e-08 33.5 9.4 3.3e-08 33.5 9.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL11 PF07400.11 KEY73970.1 - 0.11 12.2 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Interleukin 11 Mito_fiss_reg PF05308.11 KEY73970.1 - 0.22 11.6 2.7 0.42 10.7 2.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator 3Beta_HSD PF01073.19 KEY73971.1 - 3.5e-10 39.4 0.0 5.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEY73971.1 - 3.6e-10 39.7 0.0 1e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY73971.1 - 3e-06 26.6 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEY73971.1 - 5e-06 26.5 0.0 8.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEY73971.1 - 0.00069 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEY73971.1 - 0.00095 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEY73971.1 - 0.0019 17.4 0.0 0.019 14.1 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KEY73971.1 - 0.0095 15.9 0.2 0.022 14.7 0.2 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KEY73971.1 - 0.012 15.2 0.2 0.022 14.3 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KEY73972.1 - 1.7e-16 60.1 19.7 2.2e-16 59.7 19.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 KEY73973.1 - 6.6e-43 147.4 0.2 8.6e-43 147.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UL16 PF17622.2 KEY73973.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Viral unique long protein 16 Homeobox_KN PF05920.11 KEY73974.1 - 2.2e-15 56.2 1.9 2.4e-14 52.9 0.0 3.2 3 0 0 3 3 3 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KEY73974.1 - 4.9e-11 42.5 0.9 0.0012 18.8 0.0 5.3 4 1 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KEY73974.1 - 1.9e-07 30.8 0.2 8.7e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KEY73974.1 - 0.00067 20.3 1.9 0.00067 20.3 1.9 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KEY73974.1 - 0.0058 17.0 2.2 0.0058 17.0 2.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEY73974.1 - 0.41 11.2 6.3 0.76 10.3 2.0 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KEY73974.1 - 1.6 9.1 5.7 0.69 10.3 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY73974.1 - 1.8 9.0 3.9 64 4.1 1.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 KEY73975.1 - 1.1e-24 87.0 37.0 2.1e-19 69.7 15.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73975.1 - 3e-16 59.3 17.8 1.2e-14 54.0 5.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter SET PF00856.28 KEY73976.1 - 1e-09 39.0 0.0 4.1e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 SET domain UCR_hinge PF02320.16 KEY73976.1 - 2.4 8.4 9.8 0.4 10.9 0.3 2.7 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein p450 PF00067.22 KEY73977.1 - 3.4e-57 194.2 0.0 4.6e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3397 PF11877.8 KEY73977.1 - 0.034 14.4 0.9 3.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) p450 PF00067.22 KEY73979.1 - 4.7e-79 266.3 0.0 5.9e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELO PF01151.18 KEY73980.1 - 7.5e-59 199.3 18.3 9.2e-59 199.0 18.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Castor_Poll_mid PF06241.12 KEY73980.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel 4HBT_2 PF13279.6 KEY73981.1 - 1.3e-05 25.6 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF5128 PF17170.4 KEY73981.1 - 0.059 12.5 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 6-bladed beta-propeller MFS_1 PF07690.16 KEY73982.1 - 1.7e-37 129.1 59.4 1.7e-37 129.1 59.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY73982.1 - 1.8e-06 27.1 15.2 1.8e-06 27.1 15.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter SPC25 PF06703.11 KEY73982.1 - 0.98 9.2 2.3 2.5 7.9 2.3 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CDH-cyt PF16010.5 KEY73983.1 - 4.5e-36 124.2 0.0 8.1e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 KEY73983.1 - 0.0017 18.0 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KEY73983.1 - 0.078 12.9 0.0 0.35 10.9 0.0 2.2 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat NHL PF01436.21 KEY73983.1 - 0.12 12.5 0.1 11 6.3 0.0 3.5 3 0 0 3 3 3 0 NHL repeat 2OG-FeII_Oxy_2 PF13532.6 KEY73984.1 - 5.1e-14 52.9 0.1 8.5e-14 52.2 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KEY73984.1 - 0.0034 17.8 0.1 0.0079 16.7 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GMC_oxred_N PF00732.19 KEY73985.1 - 1.4e-60 205.2 0.1 1.8e-60 204.8 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY73985.1 - 1.4e-32 113.2 0.0 2.3e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEY73985.1 - 0.00038 19.6 0.2 0.00072 18.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEY73985.1 - 0.0046 16.6 0.7 0.012 15.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY73985.1 - 0.0052 17.0 0.6 0.016 15.4 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY73985.1 - 0.021 14.0 0.1 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY73985.1 - 0.029 13.6 0.5 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KEY73987.1 - 1.2e-22 80.3 0.0 6.8e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY73987.1 - 9.9e-17 61.3 0.2 2.3e-14 53.5 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY73987.1 - 5.6e-13 49.2 0.2 8.4e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY73987.1 - 0.0019 17.7 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TetR_C_20 PF17925.1 KEY73987.1 - 0.029 14.7 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_3_C PF01915.22 KEY73989.1 - 1.8e-40 139.1 0.0 6.7e-40 137.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY73989.1 - 6.2e-37 127.7 0.0 9.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY73989.1 - 7.7e-25 86.8 0.1 1.7e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Rieske PF00355.26 KEY73990.1 - 4e-09 36.3 0.0 9.2e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KEY73990.1 - 7.9e-05 22.5 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain QLQ PF08880.11 KEY73990.1 - 0.092 12.5 0.6 0.18 11.6 0.6 1.5 1 0 0 1 1 1 0 QLQ Methyltransf_2 PF00891.18 KEY73991.1 - 2.2e-23 82.7 0.0 3.3e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KEY73991.1 - 1.2e-06 28.3 0.0 3.5e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY73991.1 - 9.7e-05 23.0 0.0 0.0003 21.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEY73991.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TPR_10 PF13374.6 KEY73992.1 - 1e-81 266.8 0.0 1.6e-10 40.5 0.0 10.5 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 KEY73992.1 - 5.5e-73 241.3 0.0 1.4e-13 51.0 0.0 7.7 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KEY73992.1 - 1.9e-32 108.9 0.3 9.1e-05 22.2 0.0 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 KEY73992.1 - 8.9e-15 55.1 0.0 1.7 9.4 0.0 9.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY73992.1 - 4.4e-13 48.3 5.7 0.15 12.3 0.0 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY73992.1 - 1.2e-12 47.0 0.0 0.28 11.1 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY73992.1 - 1.2e-12 47.9 5.8 3.8e-07 29.8 0.3 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KEY73992.1 - 6.8e-11 41.7 0.4 22 6.1 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEY73992.1 - 4.3e-10 39.3 2.8 1.1 9.8 0.0 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY73992.1 - 5.5e-08 33.2 0.3 13 6.4 0.0 8.2 5 3 3 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEY73992.1 - 7.5e-08 32.6 9.9 47 5.2 0.0 9.5 9 0 0 9 9 9 0 Tetratricopeptide repeat NACHT PF05729.12 KEY73992.1 - 5.4e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KEY73992.1 - 9.1e-06 25.0 0.1 0.23 10.6 0.0 4.2 4 1 1 5 5 5 2 NB-ARC domain Urocanase_N PF17391.2 KEY73992.1 - 0.0028 17.3 0.7 23 4.7 0.0 5.1 2 1 5 7 7 6 0 Urocanase N-terminal domain TPR_3 PF07720.12 KEY73992.1 - 0.0048 16.9 0.0 1.5e+02 2.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY73992.1 - 0.035 14.3 5.6 9.9 6.7 0.0 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat AAA_25 PF13481.6 KEY73992.1 - 0.046 13.3 0.0 0.21 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain Euplotes_phero PF05842.11 KEY73992.1 - 0.05 14.2 0.0 1.6e+02 2.9 0.0 4.8 1 1 5 6 6 6 0 Euplotes octocarinatus mating pheromone protein AAA_22 PF13401.6 KEY73992.1 - 0.15 12.4 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain TPR_6 PF13174.6 KEY73992.1 - 1.1 10.1 10.4 72 4.3 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Ntox35 PF15534.6 KEY73992.1 - 1.4 9.4 12.1 20 5.7 0.0 6.1 7 0 0 7 7 7 0 Bacterial toxin 35 HTH_Tnp_Tc5 PF03221.16 KEY73993.1 - 0.0024 17.8 0.4 0.0092 16.0 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PNP_UDP_1 PF01048.20 KEY73994.1 - 2.8e-07 30.1 1.5 1.6e-06 27.5 1.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ses_B PF17046.5 KEY73994.1 - 0.2 11.6 3.3 0.41 10.7 3.3 1.5 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein BatA PF07584.11 KEY73995.1 - 0.067 13.6 7.5 0.14 12.6 0.2 4.4 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal PrgI PF12666.7 KEY73995.1 - 5.8 7.7 7.4 1.5 9.6 0.2 3.3 3 0 0 3 3 3 0 PrgI family protein Vps62 PF06101.11 KEY73996.1 - 3.9e-14 51.9 1.5 2.3e-11 42.7 0.3 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Glyco_hydro_16 PF00722.21 KEY73997.1 - 2e-08 33.9 3.1 3.5e-08 33.1 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KEY73999.1 - 4.8e-20 71.8 19.5 4.8e-20 71.8 19.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_36 PF17167.4 KEY74000.1 - 7e-66 222.6 0.2 1.5e-65 221.6 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 KEY74000.1 - 1.1e-29 103.6 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 KEY74000.1 - 4.5e-05 22.9 0.4 8.7e-05 21.9 0.4 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 KEY74000.1 - 0.00084 18.4 0.0 0.0025 16.8 0.0 1.6 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF608 PF04685.13 KEY74000.1 - 0.0035 16.6 0.2 0.0053 16.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydro_65C PF03633.15 KEY74000.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain HET PF06985.11 KEY74001.1 - 5.3e-10 39.8 7.1 5.5e-08 33.3 1.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KEY74003.1 - 2.8e-26 92.2 0.0 4.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74003.1 - 2.8e-18 66.3 0.1 3.9e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY74003.1 - 6.7e-06 25.7 0.1 2.9e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEY74003.1 - 0.041 13.8 0.5 0.47 10.3 0.7 2.3 2 0 0 2 2 2 0 KR domain Glyco_trans_4_2 PF13477.6 KEY74003.1 - 0.055 13.5 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DFP PF04127.15 KEY74003.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AAA PF00004.29 KEY74006.1 - 8.3e-17 61.9 0.0 1.4e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Utp11 PF03998.13 KEY74007.1 - 1.8e-63 214.8 24.6 2e-63 214.6 24.6 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KEY74007.1 - 0.2 11.0 0.6 0.48 9.7 0.6 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 RRN3 PF05327.11 KEY74007.1 - 8.1 4.9 9.5 11 4.4 9.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DEAD PF00270.29 KEY74008.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Cmc1 PF08583.10 KEY74009.1 - 2.9e-14 52.8 6.1 5.7e-14 51.9 6.0 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MARVEL PF01284.23 KEY74009.1 - 1.6e-09 38.0 14.4 4.8e-09 36.4 14.3 1.8 1 1 0 1 1 1 1 Membrane-associating domain CHCH PF06747.13 KEY74009.1 - 0.029 14.5 1.1 0.087 13.0 1.1 1.9 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 KEY74009.1 - 0.063 13.3 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 KEY74009.1 - 0.15 12.5 7.6 4.8 7.6 5.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) ADH_N PF08240.12 KEY74010.1 - 1.1e-28 99.3 0.2 1.1e-28 99.3 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY74010.1 - 1.4e-23 83.3 0.1 2.3e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEY74010.1 - 4.3e-11 42.7 0.4 6.6e-11 42.1 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEY74010.1 - 4.9e-07 30.9 0.0 1.6e-06 29.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEY74010.1 - 0.0016 17.7 0.8 0.0024 17.2 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KEY74010.1 - 0.0091 15.3 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY74010.1 - 0.012 14.4 0.3 0.017 13.8 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.21 KEY74010.1 - 0.015 15.4 0.7 0.54 10.3 0.3 2.6 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEY74010.1 - 0.033 13.8 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KEY74010.1 - 0.055 12.7 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY74010.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ASL_C PF08328.11 KEY74011.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal tRNA-synt_2d PF01409.20 KEY74012.1 - 1.4e-83 280.1 0.0 2.2e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KEY74012.1 - 3.7e-16 59.1 1.3 9.3e-16 57.9 0.6 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KEY74012.1 - 1e-06 28.4 0.0 0.0045 16.5 0.0 3.0 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KEY74012.1 - 7.8e-05 21.9 0.1 0.006 15.7 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Vps52 PF04129.12 KEY74012.1 - 0.0024 16.7 0.1 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family PheRS_DBD2 PF18554.1 KEY74012.1 - 0.0066 16.4 3.6 0.016 15.2 3.6 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KEY74012.1 - 0.037 14.0 0.0 0.096 12.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) PHINT_rpt PF14882.6 KEY74012.1 - 0.15 12.4 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 Phage-integrase repeat unit PALP PF00291.25 KEY74013.1 - 1.6e-44 152.5 0.2 2e-44 152.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CN_hydrolase PF00795.22 KEY74015.1 - 8.6e-40 136.7 0.0 1.2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KEY74015.1 - 2.1e-22 79.5 0.0 5.8e-22 78.0 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Egh16-like PF11327.8 KEY74016.1 - 2.3e-18 67.3 11.6 2.3e-18 67.3 11.6 3.0 2 1 0 2 2 2 1 Egh16-like virulence factor Med13_C PF06333.12 KEY74016.1 - 1.4 8.2 13.5 0.18 11.0 9.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain NOA36 PF06524.12 KEY74016.1 - 1.4 8.2 13.6 2.1 7.6 13.6 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEY74016.1 - 1.7 9.0 7.0 2.8 8.4 7.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FSA_C PF10479.9 KEY74016.1 - 4.1 5.4 16.1 6.1 4.8 16.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ADH_N_2 PF16884.5 KEY74018.1 - 2.4e-23 82.1 0.0 3.7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEY74018.1 - 1.1e-20 74.0 0.1 1.8e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY74018.1 - 4.6e-12 47.1 0.1 1e-11 46.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aa_trans PF01490.18 KEY74019.1 - 6.2e-51 173.4 34.0 7.1e-51 173.2 34.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3593 PF12159.8 KEY74019.1 - 0.6 10.2 11.3 0.072 13.1 0.7 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF3593) DUF3149 PF11346.8 KEY74019.1 - 9.5 5.9 11.1 7.4 6.3 0.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) RMI1_C PF16099.5 KEY74021.1 - 0.005 16.7 0.4 0.0065 16.3 0.4 1.2 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Leu_zip PF15294.6 KEY74021.1 - 0.0079 15.7 0.5 0.0097 15.4 0.5 1.2 1 0 0 1 1 1 1 Leucine zipper Prefoldin PF02996.17 KEY74021.1 - 0.0091 15.9 3.4 0.19 11.7 0.4 2.2 1 1 0 2 2 2 2 Prefoldin subunit CCDC92 PF14916.6 KEY74021.1 - 0.017 14.9 0.2 0.033 14.0 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ZapB PF06005.12 KEY74021.1 - 0.025 15.0 4.1 0.051 14.0 4.1 1.7 1 1 0 1 1 1 0 Cell division protein ZapB FlxA PF14282.6 KEY74021.1 - 0.052 13.5 0.6 0.075 13.0 0.1 1.5 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 KEY74021.1 - 0.079 12.7 1.5 0.12 12.1 0.5 1.7 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 KEY74021.1 - 0.16 12.4 0.9 0.67 10.4 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 KEY74021.1 - 0.41 10.9 2.5 0.46 10.7 0.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 RMI1_N PF08585.12 KEY74022.1 - 0.53 10.0 5.0 0.069 12.9 0.3 2.0 2 0 0 2 2 2 0 RecQ mediated genome instability protein PAF-AH_p_II PF03403.13 KEY74023.1 - 1.5e-45 155.4 0.0 3.9e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KEY74023.1 - 6.6e-08 31.8 0.1 2.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KEY74023.1 - 1.4e-05 24.5 0.1 0.073 12.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KEY74023.1 - 6.3e-05 22.1 0.0 0.00057 19.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Ribosomal_S30 PF04758.14 KEY74024.1 - 5e-29 100.3 5.2 5.4e-29 100.2 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 RRM_1 PF00076.22 KEY74025.1 - 3.5e-15 55.6 0.0 5.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEY74025.1 - 0.0049 16.9 0.1 0.0083 16.1 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Glyco_hydro_3_C PF01915.22 KEY74026.1 - 2.4e-61 207.3 0.0 5.3e-61 206.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY74026.1 - 6.5e-55 186.7 0.0 1e-54 186.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KEY74026.1 - 3.7e-23 82.0 0.1 5.8e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 KEY74026.1 - 1.4e-21 76.4 0.0 3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.28 KEY74028.1 - 7.5e-21 74.5 0.1 9e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF5331 PF17265.2 KEY74029.1 - 0.53 10.0 4.1 51 3.6 0.1 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5331) Atg14 PF10186.9 KEY74030.1 - 2.9e-14 52.9 0.4 2.9e-14 52.9 0.4 1.8 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KEY74030.1 - 3.4e-13 49.3 0.2 1.2e-09 37.6 0.0 3.3 3 1 0 3 3 3 2 Vacuolar protein sorting 38 Borrelia_P83 PF05262.11 KEY74030.1 - 0.44 9.0 7.6 0.83 8.1 7.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DASH_Spc19 PF08287.11 KEY74030.1 - 2.4 8.0 18.8 0.11 12.4 12.7 1.8 2 0 0 2 2 2 0 Spc19 Spc7 PF08317.11 KEY74030.1 - 7.3 5.4 12.8 14 4.4 12.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.32 KEY74031.1 - 2.5e-06 28.1 5.2 0.00072 20.3 0.9 4.2 3 0 0 3 3 3 1 WD domain, G-beta repeat bZIP_C PF12498.8 KEY74031.1 - 0.13 13.3 2.4 0.36 11.8 2.4 1.7 1 0 0 1 1 1 0 Basic leucine-zipper C terminal ANAPC4_WD40 PF12894.7 KEY74031.1 - 0.14 12.4 0.2 5.9 7.3 0.2 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 KEY74031.1 - 0.52 10.5 4.9 1.2 9.4 4.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family DUF4379 PF14311.6 KEY74031.1 - 0.96 9.9 8.3 3.9 7.9 1.1 3.0 2 0 0 2 2 2 0 Probable Zinc-ribbon domain PHD PF00628.29 KEY74031.1 - 4.7 7.2 8.8 15 5.5 0.2 3.0 2 1 1 3 3 3 0 PHD-finger zf-MYND PF01753.18 KEY74033.1 - 0.25 11.5 3.6 0.45 10.7 3.6 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 KEY74033.1 - 0.34 11.1 3.2 0.6 10.3 3.2 1.3 1 0 0 1 1 1 0 B-box zinc finger LMBR1 PF04791.16 KEY74034.1 - 1.5e-19 70.3 20.8 6.2e-18 65.0 16.1 2.6 2 1 0 2 2 2 1 LMBR1-like membrane protein Arc_PepC_II PF06847.11 KEY74034.1 - 3.2 8.3 5.6 0.58 10.7 1.3 2.0 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II CPSF_A PF03178.15 KEY74035.1 - 1.6e-78 264.3 0.0 3.3e-78 263.2 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KEY74035.1 - 1.3e-18 67.0 0.0 2.7e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pal1 PF08316.11 KEY74036.1 - 3.2e-10 40.9 0.7 7.2e-10 39.8 0.1 2.0 2 1 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 KEY74037.1 - 2.5e-81 272.6 0.2 3e-81 272.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KEY74037.1 - 0.02 14.8 0.2 0.056 13.4 0.0 1.8 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily CKS PF01111.19 KEY74038.1 - 1.7e-34 117.9 1.7 2.1e-34 117.6 1.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.15 KEY74039.1 - 5.5e-138 460.0 0.0 5.5e-138 460.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Sugar_tr PF00083.24 KEY74042.1 - 2e-128 429.1 17.7 2.3e-128 428.9 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY74042.1 - 5.6e-18 65.0 35.1 4.9e-14 52.0 11.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_64 PF09258.10 KEY74044.1 - 1.4e-56 191.5 0.0 1.8e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KEY74044.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEY74044.1 - 0.0053 16.6 0.3 0.044 13.6 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAD_binding_2 PF00890.24 KEY74045.1 - 1.3e-84 284.7 0.6 1.6e-84 284.4 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KEY74045.1 - 7.6e-22 77.3 0.1 1.6e-20 73.0 0.0 2.7 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KEY74045.1 - 9.2e-14 51.8 0.2 1.5e-13 51.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEY74045.1 - 8e-09 35.3 0.4 2.9e-08 33.5 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY74045.1 - 2.4e-07 30.9 2.2 9.3e-07 29.0 0.5 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY74045.1 - 2.9e-07 30.0 0.4 1.9e-05 24.1 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY74045.1 - 3.7e-06 26.4 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEY74045.1 - 2.4e-05 23.3 1.6 0.0087 14.8 0.2 3.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KEY74045.1 - 3.2e-05 23.3 0.4 0.01 15.1 0.1 2.8 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 KEY74045.1 - 0.0014 17.9 3.7 0.012 14.9 3.7 2.0 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KEY74045.1 - 0.0029 16.8 1.5 0.12 11.4 0.8 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEY74045.1 - 0.016 14.5 0.8 0.36 10.1 0.2 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEY74045.1 - 0.031 14.8 2.2 2.4 8.8 0.5 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEY74045.1 - 0.035 13.4 0.7 0.064 12.5 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fasciclin PF02469.22 KEY74046.1 - 0.00082 19.6 0.0 0.0019 18.4 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain SRF-TF PF00319.18 KEY74047.1 - 9.7e-22 76.2 0.3 1.5e-21 75.6 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 KEY74048.1 - 2.3e-170 567.0 1.9 2.3e-170 567.0 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Raffinose_syn PF05691.12 KEY74048.1 - 0.088 10.6 0.2 0.13 10.0 0.2 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 GFO_IDH_MocA PF01408.22 KEY74049.1 - 2.4e-14 54.2 0.0 4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CENP-L PF13092.6 KEY74050.1 - 7.2e-51 172.6 0.0 3.5e-49 167.1 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 ADH_zinc_N PF00107.26 KEY74051.1 - 5.1e-22 78.3 0.7 1e-21 77.3 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY74051.1 - 1.7e-12 48.6 0.1 3.3e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY74051.1 - 4.3e-10 39.4 0.5 9.6e-10 38.3 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Metallophos_2 PF12850.7 KEY74051.1 - 4.7e-08 33.4 1.6 5.4e-06 26.7 1.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KEY74051.1 - 1.8e-07 31.9 0.2 3.6e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TrkA_N PF02254.18 KEY74051.1 - 0.021 15.1 0.1 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KEY74051.1 - 0.036 13.4 1.9 0.11 11.7 1.9 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Transp_inhibit PF18791.1 KEY74051.1 - 0.076 12.5 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain DAO PF01266.24 KEY74052.1 - 1.7e-38 133.1 1.0 2e-38 132.9 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY74052.1 - 0.0001 22.4 0.1 0.00027 21.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY74052.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KEY74052.1 - 0.00093 19.2 0.1 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEY74052.1 - 0.0021 17.2 1.2 0.04 13.0 1.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY74052.1 - 0.019 14.2 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY74052.1 - 0.072 12.3 0.0 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_1 PF00190.22 KEY74053.1 - 8.1e-17 61.2 0.9 1e-16 60.9 0.4 1.4 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 KEY74053.1 - 0.0028 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain ADH_zinc_N PF00107.26 KEY74055.1 - 1.1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY74055.1 - 1.2e-06 28.4 0.2 4.2e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.25 KEY74056.1 - 6.7e-16 58.6 0.0 9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEY74056.1 - 6e-08 32.6 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEY74056.1 - 4.7e-07 29.8 0.0 6.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY74056.1 - 1.2e-06 28.9 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEY74056.1 - 0.0076 16.4 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEY74056.1 - 0.025 15.2 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KEY74056.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Complex1_LYR PF05347.15 KEY74057.1 - 1.6e-05 24.9 5.0 5.5e-05 23.1 1.3 3.1 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEY74057.1 - 0.0022 18.7 3.3 0.02 15.6 3.3 2.4 1 1 0 1 1 1 1 Complex1_LYR-like Ank_4 PF13637.6 KEY74058.1 - 1.4e-13 51.0 0.4 2.6e-08 34.2 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY74058.1 - 3.4e-12 46.8 0.1 0.0009 19.8 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY74058.1 - 4.2e-11 42.0 0.1 0.0036 17.7 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KEY74058.1 - 1.8e-10 40.8 0.8 0.0098 16.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.13 KEY74058.1 - 3.9e-05 23.5 0.1 0.00014 21.7 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 KEY74058.1 - 0.00017 21.8 0.3 0.16 12.3 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Hrs_helical PF12210.8 KEY74058.1 - 0.0023 18.4 5.0 0.017 15.6 5.9 2.0 2 0 0 2 2 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate OmpH PF03938.14 KEY74058.1 - 0.0035 17.7 6.7 0.01 16.2 6.7 1.7 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Filament PF00038.21 KEY74058.1 - 0.034 13.7 7.6 0.064 12.8 7.6 1.4 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.15 KEY74058.1 - 0.057 13.0 7.5 0.11 12.0 7.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KEY74058.1 - 0.077 12.1 7.7 0.028 13.5 4.9 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DDE_Tnp_IS66 PF03050.14 KEY74058.1 - 0.14 11.6 3.1 0.25 10.8 3.1 1.3 1 0 0 1 1 1 0 Transposase IS66 family Spc7 PF08317.11 KEY74058.1 - 0.16 10.9 9.7 0.12 11.3 7.6 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.9 KEY74058.1 - 0.19 10.2 6.6 0.31 9.6 6.6 1.3 1 0 0 1 1 1 0 Macoilin family Mod_r PF07200.13 KEY74058.1 - 0.27 11.4 9.9 0.61 10.2 9.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Phage_GPO PF05929.11 KEY74058.1 - 0.3 10.7 4.3 0.51 9.9 4.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 KEY74058.1 - 1.2 8.4 5.9 2.6 7.3 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KEY74058.1 - 1.3 6.9 5.0 1.8 6.4 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 KEY74058.1 - 2.1 7.1 5.0 3.1 6.5 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TMF_TATA_bd PF12325.8 KEY74058.1 - 6.6 7.0 10.8 2.3 8.5 7.4 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FYVE PF01363.21 KEY74059.1 - 5.8e-24 84.0 22.1 4.5e-17 61.9 8.7 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KEY74059.1 - 2.5e-17 62.3 0.9 5.2e-17 61.3 0.9 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KEY74059.1 - 8.5e-05 22.8 6.0 0.012 15.9 0.0 2.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KEY74059.1 - 0.00052 20.1 1.9 0.00052 20.1 1.9 4.1 4 1 1 5 5 4 1 AN1-like Zinc finger ABC_tran_CTD PF16326.5 KEY74059.1 - 0.01 16.1 4.7 0.96 9.7 1.9 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain ASL_C PF08328.11 KEY74059.1 - 0.095 12.8 0.2 18 5.4 0.0 2.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal HypA PF01155.19 KEY74059.1 - 0.14 12.2 9.9 0.096 12.7 0.4 3.6 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_9 PF16293.5 KEY74059.1 - 0.14 12.0 2.8 8.4 6.3 0.0 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Siva PF05458.12 KEY74059.1 - 0.23 11.1 5.6 7.5 6.2 2.3 2.8 2 1 0 2 2 2 0 Cd27 binding protein (Siva) PhnA_Zn_Ribbon PF08274.12 KEY74059.1 - 0.8 9.7 7.3 28 4.8 0.0 4.3 4 0 0 4 4 4 0 PhnA Zinc-Ribbon IBR PF01485.21 KEY74059.1 - 1.3 9.3 16.5 0.18 12.0 0.8 3.7 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 KEY74059.1 - 1.5 8.3 15.8 10 5.7 1.0 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KEY74059.1 - 2.1 9.4 0.0 2.1 9.4 0.0 6.0 5 1 1 6 6 6 0 C2H2-type zinc finger TMF_TATA_bd PF12325.8 KEY74059.1 - 3.2 8.0 12.2 0.087 13.0 3.2 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-C2HC5 PF06221.13 KEY74059.1 - 6 6.9 19.6 7 6.7 0.2 4.7 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type TMF_DNA_bd PF12329.8 KEY74059.1 - 7.6 6.6 11.3 18 5.4 0.9 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding zinc_ribbon_9 PF14369.6 KEY74059.1 - 8.2 6.8 10.5 3.5 8.0 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon C6_DPF PF10170.9 KEY74059.1 - 9 6.7 9.8 0.2 12.1 1.3 2.6 2 1 0 2 2 2 0 Cysteine-rich domain DUF4140 PF13600.6 KEY74059.1 - 9.9 6.7 6.8 16 6.0 1.7 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) NAD_binding_7 PF13241.6 KEY74060.1 - 3.8e-30 104.4 0.1 6.3e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KEY74060.1 - 3.5e-27 93.8 0.0 6.1e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KEY74060.1 - 5.6e-14 51.3 0.5 1e-13 50.4 0.5 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KEY74060.1 - 0.00097 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEY74060.1 - 0.0079 16.5 0.3 0.014 15.6 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KEY74060.1 - 0.068 13.8 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cytotoxic PF09000.10 KEY74060.1 - 0.096 13.0 0.1 0.58 10.5 0.1 2.0 2 0 0 2 2 2 0 Cytotoxic A_deaminase PF00962.22 KEY74061.1 - 1.4e-28 100.2 0.0 2.1e-21 76.6 0.0 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Peptidase_M14 PF00246.24 KEY74062.1 - 1.4e-71 241.7 0.0 1.8e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ldi PF18566.1 KEY74063.1 - 6.6e-114 380.7 0.0 1.3e-113 379.7 0.0 1.5 1 1 0 1 1 1 1 Linalool dehydratase/isomerase MFS_1 PF07690.16 KEY74064.1 - 2.7e-35 121.9 29.1 2.7e-35 121.9 29.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidoligase_2 PF12224.8 KEY74065.1 - 7.7e-07 29.0 0.1 7.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Exonuc_VII_S PF02609.16 KEY74067.1 - 0.77 9.9 4.6 2.2 8.4 0.5 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit Glyco_hydro_18 PF00704.28 KEY74069.1 - 2.4e-69 234.4 0.0 3.1e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEY74069.1 - 8.4e-13 48.6 17.0 8.4e-13 48.6 17.0 5.4 5 1 0 5 5 5 2 Chitin recognition protein LysM PF01476.20 KEY74070.1 - 4.4e-14 52.3 0.0 0.00079 19.4 0.0 4.6 4 0 0 4 4 4 4 LysM domain NACHT PF05729.12 KEY74072.1 - 1.5e-08 34.8 0.0 3.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KEY74072.1 - 4.3e-05 24.0 0.2 0.0082 16.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KEY74072.1 - 0.00054 20.3 0.1 0.0061 17.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KEY74072.1 - 0.0052 17.3 0.1 0.18 12.4 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74072.1 - 0.018 15.5 0.0 0.6 10.8 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat AAA_22 PF13401.6 KEY74072.1 - 0.047 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KEY74073.1 - 1.4e-51 175.3 0.0 3e-37 128.1 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY74073.1 - 0.0072 16.7 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEY74073.1 - 0.16 11.8 0.0 0.63 9.8 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase DZR PF12773.7 KEY74073.1 - 0.53 10.4 3.6 1.5 8.9 3.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KEY74073.1 - 5 6.7 7.4 9.2 5.9 1.0 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KEY74073.1 - 5.1 7.1 6.3 30 4.7 1.2 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain MFS_1 PF07690.16 KEY74074.1 - 1.4e-33 116.3 26.8 1.5e-33 116.2 26.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily YrhC PF14143.6 KEY74074.1 - 3.1 7.9 5.0 3.9 7.6 0.3 3.4 3 0 0 3 3 3 0 YrhC-like protein DUF3723 PF12520.8 KEY74077.1 - 5.9e-57 193.5 4.7 5.1e-56 190.4 2.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) Med9 PF07544.13 KEY74078.1 - 0.0029 17.6 6.2 0.007 16.4 6.2 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 KEY74078.1 - 0.0049 17.0 3.0 0.012 15.7 3.0 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Perilipin PF03036.16 KEY74078.1 - 0.0049 15.9 3.4 0.0057 15.7 3.4 1.1 1 0 0 1 1 1 1 Perilipin family CENP-Q PF13094.6 KEY74078.1 - 0.0088 16.3 8.1 0.03 14.5 8.1 1.8 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.9 KEY74078.1 - 0.011 16.0 12.1 0.014 15.6 12.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KEY74078.1 - 0.016 15.5 8.7 0.022 15.1 8.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KLRAQ PF10205.9 KEY74078.1 - 0.15 12.3 8.2 0.069 13.4 5.5 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1811 PF08838.10 KEY74078.1 - 0.16 12.2 2.7 0.2 11.9 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1811) E2F_CC-MB PF16421.5 KEY74078.1 - 0.25 11.7 5.5 0.26 11.7 3.3 2.0 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain NuA4 PF09340.10 KEY74078.1 - 0.34 10.8 4.5 1.7 8.6 4.5 2.0 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Mt_ATP-synt_B PF05405.14 KEY74078.1 - 0.38 10.4 6.8 0.5 10.0 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sugarporin_N PF11471.8 KEY74078.1 - 0.38 10.7 3.3 0.88 9.6 3.3 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension V_ATPase_I PF01496.19 KEY74078.1 - 0.44 8.4 6.5 0.51 8.2 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CHD5 PF04420.14 KEY74078.1 - 0.61 9.9 3.0 0.53 10.1 1.9 1.5 1 1 0 1 1 1 0 CHD5-like protein ADIP PF11559.8 KEY74078.1 - 0.82 9.7 14.4 0.57 10.3 12.7 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KEY74078.1 - 0.89 9.9 10.0 0.66 10.4 6.8 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 KEY74078.1 - 0.92 8.8 7.7 1.2 8.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 KEY74078.1 - 2 6.9 10.7 2.3 6.6 10.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF4094 PF13334.6 KEY74078.1 - 3.5 8.1 6.6 0.85 10.1 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) MAP65_ASE1 PF03999.12 KEY74079.1 - 0.0094 14.7 0.2 0.011 14.5 0.2 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF3704 PF12488.8 KEY74079.1 - 0.051 13.2 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) TMF_TATA_bd PF12325.8 KEY74080.1 - 0.0079 16.4 3.4 0.035 14.3 3.4 2.0 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 KEY74080.1 - 0.009 16.3 0.1 0.009 16.3 0.1 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FmiP_Thoc5 PF09766.9 KEY74080.1 - 0.0093 15.3 0.2 0.017 14.4 0.2 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF2046 PF09755.9 KEY74080.1 - 0.017 14.4 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DASH_Dad3 PF08656.10 KEY74080.1 - 0.16 12.1 0.5 0.85 9.8 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4094 PF13334.6 KEY74080.1 - 0.59 10.6 2.2 1.3 9.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SKA2 PF16740.5 KEY74080.1 - 0.78 9.5 8.6 0.36 10.6 5.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 KEY74080.1 - 0.85 10.0 5.7 1.2 9.5 0.7 3.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C2H2 PF00096.26 KEY74084.1 - 1.9e-05 24.9 21.8 0.0015 18.8 0.5 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY74084.1 - 0.0059 17.4 0.6 0.0059 17.4 0.6 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger FOXP-CC PF16159.5 KEY74084.1 - 0.68 10.6 8.3 1.9 9.2 1.1 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KEY74084.1 - 1.2 9.2 4.0 0.91 9.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF202 PF02656.15 KEY74085.1 - 3.5e-05 24.2 4.6 4.5e-05 23.8 2.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4282 PF14110.6 KEY74085.1 - 0.024 15.3 2.6 0.035 14.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) FtsX PF02687.21 KEY74085.1 - 0.038 14.5 1.3 0.05 14.1 1.3 1.2 1 0 0 1 1 1 0 FtsX-like permease family Zn_clus PF00172.18 KEY74086.1 - 2.3e-07 30.8 8.4 3.7e-07 30.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 KEY74087.1 - 3.1e-24 86.8 2.9 5.9e-24 85.9 2.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family CFEM PF05730.11 KEY74087.1 - 1.8e-09 37.5 11.5 1.8e-09 37.5 11.5 1.6 2 0 0 2 2 2 1 CFEM domain Abhydrolase_1 PF00561.20 KEY74087.1 - 2.1e-08 34.1 0.0 1e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEY74087.1 - 9.9e-08 31.5 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEY74087.1 - 0.00035 20.8 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 KEY74087.1 - 0.061 13.4 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein Ribul_P_3_epim PF00834.19 KEY74088.1 - 5.5e-61 205.4 0.0 2.3e-60 203.4 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KEY74088.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 KEY74088.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KEY74088.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Ofd1_CTDD PF10637.9 KEY74089.1 - 4e-99 331.1 0.0 2.1e-92 309.1 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KEY74089.1 - 3.6e-26 91.7 0.0 3e-25 88.7 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KEY74089.1 - 6.6e-13 49.4 0.0 1.3e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF515 PF04415.12 KEY74089.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FmdE PF02663.14 KEY74089.1 - 0.14 12.2 0.3 1.8 8.6 0.1 2.4 1 1 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CUE PF02845.16 KEY74091.1 - 1.2e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.16 KEY74092.1 - 3.2e-40 138.1 57.7 9.1e-38 130.1 54.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_like_2 PF16357.5 KEY74092.1 - 8.7 6.3 6.9 1.1 9.2 0.7 2.6 3 1 0 3 3 3 0 Putative PepSY_TM-like PhoLip_ATPase_C PF16212.5 KEY74093.1 - 1.7e-65 221.2 14.1 1.7e-65 221.2 14.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEY74093.1 - 7.1e-20 70.5 2.0 7.9e-19 67.1 0.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEY74093.1 - 4.8e-13 49.9 0.0 8.8e-07 29.4 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEY74093.1 - 2.2e-10 40.5 0.0 2.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KEY74093.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEY74093.1 - 0.018 14.8 0.1 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY74093.1 - 0.05 14.0 0.0 17 5.8 0.0 2.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEY74093.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIIB PF00382.19 KEY74094.1 - 2e-32 111.0 0.2 4.7e-19 68.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KEY74094.1 - 6.5e-12 44.8 4.5 1.2e-11 43.9 4.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KEY74094.1 - 1.1e-05 25.5 0.1 0.0004 20.4 0.0 2.2 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_Tnp_ISL3 PF13542.6 KEY74094.1 - 0.0034 16.7 0.0 0.14 11.6 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.23 KEY74094.1 - 0.0063 16.3 0.4 0.041 13.6 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEY74094.1 - 0.008 16.3 0.0 3.1 7.9 0.0 2.8 1 1 2 3 3 3 1 Cyclin, C-terminal domain Trm112p PF03966.16 KEY74094.1 - 0.049 14.2 0.1 0.2 12.3 0.1 2.3 1 1 0 1 1 1 0 Trm112p-like protein TFIIB_C_1 PF18542.1 KEY74094.1 - 0.085 12.9 0.2 5 7.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 HTH_36 PF13730.6 KEY74094.1 - 0.18 11.8 0.0 38 4.3 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain Glycos_transf_3 PF00591.21 KEY74095.1 - 5.3e-60 203.1 0.0 9.6e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KEY74095.1 - 3e-13 49.4 0.3 5.8e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CoA_transf_3 PF02515.17 KEY74097.1 - 1.5e-106 356.6 0.0 2.3e-106 356.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Asn_synthase PF00733.21 KEY74101.1 - 9.5e-19 68.3 1.9 1.1e-09 38.5 0.2 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KEY74101.1 - 2.1e-07 30.9 0.0 1.3e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KEY74101.1 - 0.069 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain zf-C2H2 PF00096.26 KEY74102.1 - 0.0055 17.1 2.3 0.0055 17.1 2.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KEY74102.1 - 0.023 14.5 8.2 0.038 13.8 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KEY74102.1 - 2.6 9.1 14.6 0.34 11.9 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger PMT PF02366.18 KEY74105.1 - 4.4e-83 278.6 15.7 6.9e-83 278.0 15.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEY74105.1 - 3e-69 232.6 3.6 3e-69 232.6 3.6 3.4 4 0 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEY74105.1 - 1.5e-20 73.8 0.4 3.8e-20 72.5 0.2 1.5 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 KEY74105.1 - 0.025 14.8 15.5 0.04 14.1 7.1 3.6 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Fascin PF06268.13 KEY74105.1 - 0.17 12.2 0.1 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Fascin domain Ribonuc_L-PSP PF01042.21 KEY74106.1 - 5.7e-40 136.1 0.0 7.1e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 KEY74107.1 - 1.2e-16 60.7 12.6 0.00057 20.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY74107.1 - 6.8e-07 29.5 0.0 0.071 13.4 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KEY74108.1 - 2.4e-08 33.7 0.0 6.2e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEY74108.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEY74108.1 - 0.0008 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KEY74108.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 SET_assoc PF11767.8 KEY74108.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Autophagy_act_C PF03987.15 KEY74109.1 - 3.9e-14 53.0 0.1 7.2e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.20 KEY74110.1 - 9.3e-167 555.5 0.0 1.1e-166 555.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.21 KEY74111.1 - 1.4e-137 459.2 35.6 1.8e-137 458.9 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEY74111.1 - 8.6e-34 117.1 36.9 1.1e-33 116.8 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease Sortilin-Vps10 PF15902.5 KEY74113.1 - 8.4e-288 954.3 26.5 5.1e-147 490.3 13.6 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KEY74113.1 - 5.1e-90 300.3 24.5 1.9e-46 158.5 9.5 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KEY74113.1 - 3.4e-10 38.4 47.5 0.74 10.1 0.3 11.7 11 0 0 11 11 11 7 BNR/Asp-box repeat BNR_2 PF13088.6 KEY74113.1 - 6.7e-08 32.2 8.4 0.22 10.8 0.2 6.8 5 3 1 6 6 6 3 BNR repeat-like domain CHB_HEX_C PF03174.13 KEY74113.1 - 0.042 13.8 4.6 1.2 9.1 0.1 4.6 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 KEY74113.1 - 0.071 13.1 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PSII_BNR PF14870.6 KEY74113.1 - 0.2 10.9 4.9 5.3 6.2 0.0 4.6 4 2 2 6 6 6 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 KEY74113.1 - 3.5 8.0 18.9 5.8 7.3 0.3 7.1 8 0 0 8 8 8 0 BNR-Asp box repeat Med16 PF11635.8 KEY74115.1 - 4.4e-67 226.6 0.0 1.6e-32 112.4 0.0 2.1 1 1 1 2 2 2 2 Mediator complex subunit 16 Filament PF00038.21 KEY74116.1 - 0.0029 17.3 7.8 0.0029 17.3 7.8 6.6 5 2 1 6 6 6 4 Intermediate filament protein PLAC9 PF15205.6 KEY74116.1 - 0.017 15.5 0.2 0.083 13.3 0.2 2.2 1 0 0 1 1 1 0 Placenta-specific protein 9 Ammonium_transp PF00909.21 KEY74117.1 - 5.6e-118 394.1 27.2 6.4e-118 393.9 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 KEY74117.1 - 0.049 13.6 0.6 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF441) DUF4131 PF13567.6 KEY74117.1 - 3.2 7.4 5.9 6.9 6.3 3.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DNA_pol_B_palm PF14792.6 KEY74118.1 - 4e-36 123.7 0.0 7.3e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KEY74118.1 - 3e-26 91.3 0.2 3.7e-25 87.9 0.3 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KEY74118.1 - 8.4e-20 70.3 1.0 2.2e-19 69.0 1.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KEY74118.1 - 3.5e-17 62.5 0.1 8.9e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Tim17 PF02466.19 KEY74119.1 - 4.8e-13 49.5 0.1 8.3e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KEY74119.1 - 0.033 14.3 0.2 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) PCI PF01399.27 KEY74120.1 - 5.7e-14 52.5 0.0 2.8e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KEY74120.1 - 0.018 14.8 0.6 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TetR_C_20 PF17925.1 KEY74120.1 - 0.11 12.8 1.0 0.32 11.3 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipase_GDSL_2 PF13472.6 KEY74121.1 - 5.2e-21 75.9 0.0 6.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY74121.1 - 1.6e-06 28.2 0.0 5.1e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rad17 PF03215.15 KEY74122.1 - 4.8e-25 88.6 0.0 1.1e-24 87.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KEY74122.1 - 3e-05 24.5 0.0 8.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEY74122.1 - 0.0012 19.3 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEY74122.1 - 0.003 17.7 0.0 0.0078 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEY74122.1 - 0.0035 17.6 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEY74122.1 - 0.0045 16.7 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEY74122.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KEY74122.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KEY74122.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KEY74122.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KEY74122.1 - 0.023 15.0 0.2 0.08 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY74122.1 - 0.033 14.7 0.0 0.086 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEY74122.1 - 0.064 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KEY74122.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Questin_oxidase PF14027.6 KEY74123.1 - 2.8e-86 290.1 0.2 3.5e-86 289.8 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like HECT_2 PF09814.9 KEY74124.1 - 1.6e-94 316.8 1.2 2.3e-94 316.3 1.2 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.23 KEY74124.1 - 5e-36 124.2 0.0 3.6e-33 114.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEY74124.1 - 1.4e-06 28.6 0.1 3.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNARE PF05739.19 KEY74124.1 - 0.13 12.3 0.2 0.77 9.8 0.2 2.3 2 0 0 2 2 2 0 SNARE domain F-box-like PF12937.7 KEY74126.1 - 0.00043 20.1 0.0 0.0019 18.1 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEY74126.1 - 0.0056 16.5 0.4 0.15 11.9 0.3 2.9 2 2 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KEY74126.1 - 0.036 14.5 12.1 0.92 10.0 0.4 4.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEY74126.1 - 3.3 7.5 11.0 3.3 7.5 3.7 3.2 3 0 0 3 3 3 0 Leucine rich repeat Glyco_hydro_115 PF15979.5 KEY74128.1 - 7e-133 443.3 1.2 1.1e-132 442.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEY74128.1 - 2e-39 135.2 0.0 4e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain BTB PF00651.31 KEY74133.1 - 0.00023 21.3 0.0 0.00062 20.0 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KEY74134.1 - 0.069 14.0 9.9 0.4 11.6 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KEY74134.1 - 2 8.9 3.6 5.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KEY74134.1 - 8.7 7.0 10.5 11 6.7 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 KEY74136.1 - 1.7e-44 152.2 0.0 2.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74136.1 - 3.3e-28 98.7 0.0 4.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY74136.1 - 0.0016 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY74136.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY74136.1 - 0.069 13.1 0.2 0.92 9.4 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KEY74136.1 - 0.2 11.2 0.0 0.54 9.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family MTBP_C PF14920.6 KEY74136.1 - 4.9 6.8 7.2 52 3.5 7.2 2.2 1 1 0 1 1 1 0 MDM2-binding Neuroparsin PF07327.11 KEY74137.1 - 0.13 12.8 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Neuroparsin Pkinase PF00069.25 KEY74138.1 - 3.7e-56 190.4 0.0 6.5e-51 173.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74138.1 - 2.7e-33 115.4 0.0 1.3e-31 109.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY74138.1 - 9e-09 35.0 0.0 3.1e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEY74138.1 - 0.00035 20.6 0.2 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY74138.1 - 0.12 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sybindin PF04099.12 KEY74139.1 - 1.9e-24 86.2 0.0 2.2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Peroxin-3 PF04882.12 KEY74140.1 - 5.3e-172 573.0 0.6 6.1e-172 572.8 0.6 1.0 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KEY74141.1 - 4.9e-52 176.0 0.0 6.2e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Forkhead PF00250.18 KEY74142.1 - 1e-33 115.4 0.2 1.8e-33 114.6 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain EF-hand_4 PF12763.7 KEY74143.1 - 4.8e-24 84.3 0.0 9.9e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KEY74143.1 - 0.00041 20.1 0.9 0.026 14.4 0.1 2.7 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.6 KEY74143.1 - 0.0013 19.1 0.0 0.17 12.4 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair E3_binding PF02817.17 KEY74143.1 - 0.086 13.2 2.0 0.23 11.9 0.1 2.7 3 0 0 3 3 3 0 e3 binding domain EF-hand_1 PF00036.32 KEY74143.1 - 0.17 11.5 0.0 0.5 10.0 0.0 1.9 1 0 0 1 1 1 0 EF hand LRR_4 PF12799.7 KEY74144.1 - 0.00056 20.2 5.4 2.5 8.6 0.0 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEY74144.1 - 0.0017 18.2 0.1 0.0017 18.2 0.1 5.3 6 0 0 6 6 6 1 Leucine Rich repeat HupH_C PF04809.13 KEY74144.1 - 0.0081 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 HupH hydrogenase expression protein, C-terminal conserved region NAD_binding_1 PF00175.21 KEY74145.1 - 4.6e-29 101.2 0.0 7e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEY74145.1 - 1.2e-28 99.3 0.0 1.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEY74145.1 - 7.5e-05 22.9 0.0 0.0035 17.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_1 PF00515.28 KEY74146.1 - 1.5e-27 94.2 27.8 4.2e-06 26.4 0.3 11.6 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74146.1 - 2.3e-25 86.6 33.5 0.00018 21.3 0.2 12.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74146.1 - 2.5e-21 74.0 14.1 0.00046 20.2 0.2 11.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEY74146.1 - 6.1e-19 68.1 19.0 3e-06 27.4 2.0 9.4 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74146.1 - 2.5e-16 58.9 29.2 0.026 15.3 0.3 12.5 12 2 2 14 14 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74146.1 - 3.6e-14 51.6 16.0 0.0041 17.0 0.1 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74146.1 - 1.1e-13 51.5 28.9 0.00052 20.5 0.1 9.8 8 2 4 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 KEY74146.1 - 1.7e-11 44.0 20.2 0.24 12.1 0.0 11.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEY74146.1 - 5.6e-11 42.0 10.8 0.15 12.5 0.1 10.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEY74146.1 - 1.7e-07 30.8 27.8 0.028 14.1 0.4 9.1 9 0 0 9 9 8 3 TPR repeat TPR_10 PF13374.6 KEY74146.1 - 1.2e-06 28.2 17.7 0.63 10.0 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74146.1 - 1.3e-06 28.9 34.3 0.00043 20.9 0.5 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEY74146.1 - 0.00064 19.0 0.6 0.00064 19.0 0.6 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY74146.1 - 0.0031 17.7 17.5 0.01 16.1 2.3 6.3 7 0 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 KEY74146.1 - 0.51 11.1 9.1 46 4.9 0.0 6.5 7 0 0 7 7 7 0 Sel1 repeat Gly-rich_Ago1 PF12764.7 KEY74147.1 - 0.32 11.8 5.7 0.15 12.9 2.2 2.1 2 1 0 2 2 2 0 Glycine-rich region of argonaut PX PF00787.24 KEY74148.1 - 2.2e-18 66.3 0.0 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KEY74148.1 - 3.9e-10 39.7 10.4 1.7e-05 24.5 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KEY74148.1 - 0.032 13.7 0.2 0.23 10.9 0.4 2.0 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Cas_Csy4 PF09618.10 KEY74148.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) mRNA_cap_enzyme PF01331.19 KEY74149.1 - 1.4e-54 184.9 0.1 2.1e-54 184.3 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KEY74149.1 - 3.7e-36 124.0 0.5 6.3e-36 123.3 0.5 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KEY74149.1 - 8.7e-07 28.8 0.0 0.0002 21.1 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KEY74149.1 - 0.0046 17.3 0.0 0.0076 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Vip3A_N PF12495.8 KEY74149.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Cnd1 PF12717.7 KEY74151.1 - 0.00064 19.8 0.3 0.72 9.9 0.0 4.9 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 KorB PF08535.10 KEY74151.1 - 0.0014 18.6 0.1 0.18 11.8 0.0 3.0 2 0 0 2 2 2 1 KorB domain HEAT PF02985.22 KEY74151.1 - 0.0027 17.8 0.5 6.3 7.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Nitr_red_assoc PF09655.10 KEY74151.1 - 0.098 13.3 0.1 29 5.3 0.1 2.8 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF3511 PF12023.8 KEY74151.1 - 0.12 12.2 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) SPESP1 PF15754.5 KEY74151.1 - 0.13 11.4 2.4 0.37 9.9 2.4 1.7 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 SNF5 PF04855.12 KEY74152.1 - 3.2e-64 217.0 0.0 4.1e-63 213.4 0.0 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 KEY74153.1 - 6.2e-07 29.3 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KEY74154.1 - 4.8e-14 52.0 18.7 6.8e-09 35.5 10.1 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KEY74154.1 - 0.0016 18.3 9.5 0.21 11.5 2.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KEY74154.1 - 0.18 11.4 11.2 0.76 9.4 4.9 2.8 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KEY74154.1 - 0.63 9.6 8.1 1.3 8.6 2.5 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 KEY74154.1 - 3.9 7.6 11.3 2.6 8.2 0.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PUF PF00806.19 KEY74155.1 - 7.5e-26 88.3 0.0 4e-05 23.0 0.0 5.5 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KEY74155.1 - 5.6e-13 48.5 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KEY74156.1 - 1.1e-67 228.2 2.4 1.2e-66 224.8 2.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74156.1 - 9.1e-53 179.2 0.1 1.6e-52 178.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KEY74156.1 - 1.8e-23 82.7 0.4 7.6e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 KEY74156.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEY74156.1 - 1.2e-05 24.3 0.0 3.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 KEY74156.1 - 2.6e-05 24.6 0.0 9.2e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 KEY74156.1 - 0.00018 20.6 1.3 0.00047 19.2 1.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 KEY74156.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 PH domain APH PF01636.23 KEY74156.1 - 0.027 14.4 0.2 0.027 14.4 0.2 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEY74156.1 - 0.036 13.1 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HGTP_anticodon PF03129.20 KEY74157.1 - 3.9e-22 78.2 0.9 2.9e-21 75.4 0.0 2.8 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEY74157.1 - 2e-07 31.2 0.0 1.7e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AA_kinase PF00696.28 KEY74158.1 - 3.3e-40 138.2 2.4 4.4e-40 137.8 2.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KEY74158.1 - 5.3e-15 55.1 1.0 1.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 KEY74159.1 - 2.7e-69 232.3 0.9 3.5e-69 232.0 0.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 KEY74159.1 - 0.055 13.8 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein SprT-like PF10263.9 KEY74159.1 - 0.06 13.2 1.8 0.072 13.0 0.7 1.8 1 1 1 2 2 2 0 SprT-like family Pkinase PF00069.25 KEY74160.1 - 3.1e-68 230.0 0.0 4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74160.1 - 6.9e-42 143.5 0.0 9.7e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY74160.1 - 2.8e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY74160.1 - 0.0018 17.7 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEY74160.1 - 0.045 12.7 0.0 0.045 12.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KEY74160.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KEY74160.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KEY74160.1 - 0.11 12.3 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY74160.1 - 0.15 10.8 1.5 0.23 10.2 1.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase TIP41 PF04176.13 KEY74161.1 - 7.4e-68 227.4 0.4 9.2e-68 227.1 0.4 1.1 1 0 0 1 1 1 1 TIP41-like family DEAD PF00270.29 KEY74163.1 - 4.5e-29 101.4 0.0 8e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY74163.1 - 1e-18 67.7 0.0 3.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEY74163.1 - 3.5e-07 30.4 0.0 1.9e-05 24.7 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Docking PF08990.11 KEY74163.1 - 0.032 13.8 0.1 0.096 12.3 0.1 1.9 1 0 0 1 1 1 0 Erythronolide synthase docking Mg_chelatase PF01078.21 KEY74163.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SecA_DEAD PF07517.14 KEY74163.1 - 0.15 11.3 0.0 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain AMPK1_CBM PF16561.5 KEY74164.1 - 3.9e-08 33.4 0.0 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 KEY74165.1 - 7e-17 62.2 6.9 7e-17 62.2 6.9 3.6 2 1 1 3 3 3 1 Transcription factor Iwr1 His_Phos_1 PF00300.22 KEY74167.1 - 9.9e-18 64.5 0.0 4.8e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LRR_6 PF13516.6 KEY74168.1 - 5.6e-14 50.9 15.9 0.00023 20.9 0.0 7.5 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 KEY74168.1 - 1.1e-11 44.4 0.1 3.9e-11 42.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY74168.1 - 2.5e-09 36.8 0.2 2.5e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KEY74168.1 - 1.3e-06 28.6 12.0 0.0035 17.7 0.1 5.5 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) PRANC PF09372.10 KEY74168.1 - 0.007 16.7 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 2 1 PRANC domain LRR_1 PF00560.33 KEY74168.1 - 0.42 11.3 19.0 2.1 9.2 0.3 7.4 8 1 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 KEY74168.1 - 0.59 10.4 4.6 18 5.7 0.0 4.6 5 1 1 6 6 6 0 Ste50p, sterile alpha motif Pkinase PF00069.25 KEY74169.1 - 9.2e-59 198.9 0.0 1.3e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74169.1 - 1.2e-20 73.9 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEY74169.1 - 5.2e-06 25.6 0.0 8.8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KEY74169.1 - 0.00021 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEY74169.1 - 0.0044 16.6 0.1 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KEY74169.1 - 0.008 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEY74169.1 - 0.031 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zinc_ribbon_16 PF17034.5 KEY74170.1 - 2.1e-18 66.7 7.7 4.1e-18 65.8 7.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KEY74170.1 - 6.9e-07 28.8 4.1 6.9e-07 28.8 4.1 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PDEase_I PF00233.19 KEY74170.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Efg1 PF10153.9 KEY74171.1 - 1.8e-32 112.1 7.2 3.5e-32 111.2 7.2 1.5 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Glycohydro_20b2 PF14845.6 KEY74171.1 - 0.054 14.2 0.5 0.12 13.0 0.5 1.6 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like PrkA PF06798.12 KEY74171.1 - 0.44 10.1 5.3 0.68 9.5 5.3 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain DUF3835 PF12927.7 KEY74171.1 - 1.5 9.7 7.2 10 7.0 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3835) dsrm PF00035.26 KEY74172.1 - 7e-05 23.5 0.1 0.0003 21.4 0.1 2.1 2 1 0 2 2 2 1 Double-stranded RNA binding motif PTS_2-RNA PF01885.16 KEY74173.1 - 8.6e-63 211.7 0.0 1e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF5304 PF17230.2 KEY74174.1 - 1.5 9.0 5.7 15 5.8 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5304) Mlh1_C PF16413.5 KEY74175.1 - 2.2e-99 332.2 0.0 4.1e-99 331.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KEY74175.1 - 2.9e-34 117.3 0.0 5.2e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEY74175.1 - 5.8e-11 42.4 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEY74175.1 - 6e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.22 KEY74176.1 - 0.0008 19.5 0.7 0.38 11.1 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 KEY74176.1 - 0.52 10.4 3.3 5.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF202 PF02656.15 KEY74178.1 - 8.2e-11 42.2 0.2 8.2e-11 42.2 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF202) PMP22_Claudin PF00822.20 KEY74178.1 - 0.0047 16.8 1.0 0.007 16.2 1.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1634 PF07843.11 KEY74178.1 - 0.97 9.5 7.4 0.71 10.0 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1634) Lig_chan PF00060.26 KEY74178.1 - 2.3 8.0 4.7 1.8 8.4 0.7 2.1 1 1 1 2 2 2 0 Ligand-gated ion channel ABC_tran PF00005.27 KEY74179.1 - 6e-21 75.4 0.0 6.9e-09 36.3 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEY74179.1 - 4e-08 33.4 0.4 0.0086 15.9 0.2 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KEY74179.1 - 3.6e-06 27.1 0.0 0.0036 17.5 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KEY74179.1 - 0.00076 20.0 0.1 0.059 13.9 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY74179.1 - 0.0044 16.7 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KEY74179.1 - 0.016 14.9 0.0 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEY74179.1 - 0.044 13.9 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEY74179.1 - 0.053 13.9 0.3 4.1 7.7 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KEY74179.1 - 0.064 13.6 0.0 2.5 8.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase Ploopntkinase1 PF18748.1 KEY74179.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_22 PF13401.6 KEY74179.1 - 0.085 13.1 0.0 5.1 7.4 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 KEY74179.1 - 0.1 12.6 0.0 37 4.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KEY74179.1 - 0.1 13.0 0.1 0.88 10.0 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KEY74179.1 - 0.24 11.1 0.1 13 5.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain UMP1 PF05348.11 KEY74180.1 - 1.7e-44 150.8 0.0 2.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KEY74181.1 - 6e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEY74181.1 - 0.0003 20.5 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KEY74181.1 - 0.0015 19.0 0.0 0.0043 17.6 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Adaptin_N PF01602.20 KEY74182.1 - 2.4e-123 412.5 8.0 2.5e-123 412.4 7.1 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KEY74182.1 - 6.9e-55 185.5 7.4 2.2e-54 183.9 0.1 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEY74182.1 - 1.1e-16 61.0 4.6 7.2e-06 26.3 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KEY74182.1 - 1.4e-10 40.5 2.7 0.00055 20.0 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KEY74182.1 - 7e-05 23.2 2.3 5.2 7.7 0.0 6.5 6 0 0 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KEY74182.1 - 0.0026 17.7 0.0 4.3 7.4 0.0 4.2 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KEY74182.1 - 0.0042 16.7 1.7 0.63 9.6 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal DUF4042 PF13251.6 KEY74182.1 - 0.01 15.6 0.0 0.16 11.7 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) RICTOR_N PF14664.6 KEY74182.1 - 0.016 14.2 6.2 1.9 7.4 0.1 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Arm PF00514.23 KEY74182.1 - 0.031 14.3 2.2 5.1 7.3 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KEY74182.1 - 0.046 13.9 1.1 2.5 8.3 0.1 3.3 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 KEY74182.1 - 0.27 11.2 2.1 0.47 10.3 0.7 2.1 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1077 PF06417.12 KEY74183.1 - 2.4e-48 163.0 5.4 3e-48 162.7 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.9 KEY74184.1 - 5.1e-10 39.5 1.5 3e-08 33.8 0.2 2.9 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KEY74184.1 - 0.0021 18.0 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 SNARE domain Jnk-SapK_ap_N PF09744.9 KEY74184.1 - 0.014 15.6 9.3 0.051 13.8 2.8 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LigA PF07746.11 KEY74184.1 - 0.079 13.1 2.4 0.12 12.5 0.3 2.4 3 0 0 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit ST7 PF04184.12 KEY74184.1 - 0.11 10.9 0.2 0.2 10.1 0.0 1.4 2 0 0 2 2 2 0 ST7 protein BLOC1_2 PF10046.9 KEY74184.1 - 2.2 8.7 7.0 2.3 8.6 1.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KEY74184.1 - 2.5 8.3 7.4 5.3 7.2 0.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Aminotran_1_2 PF00155.21 KEY74185.1 - 5.3e-79 266.0 0.0 8.6e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PEMT PF04191.13 KEY74186.1 - 1.8e-56 189.1 11.8 1.4e-34 118.7 2.8 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KEY74186.1 - 0.0037 17.8 0.1 0.093 13.3 0.1 2.4 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KEY74186.1 - 0.0045 16.8 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Zn_clus PF00172.18 KEY74187.1 - 4.7e-09 36.2 7.9 4.7e-09 36.2 7.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4685 PF15737.5 KEY74187.1 - 0.18 12.3 0.6 0.42 11.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) OS-D PF03392.13 KEY74187.1 - 0.26 11.4 1.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D IBR PF01485.21 KEY74188.1 - 6.7e-14 51.9 40.3 3.8e-08 33.4 9.6 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KEY74188.1 - 7.5e-05 22.5 1.9 7.5e-05 22.5 1.9 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEY74188.1 - 0.0016 18.7 6.3 0.0016 18.7 6.3 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KEY74188.1 - 0.0065 16.4 7.2 0.0065 16.4 7.2 3.2 3 0 0 3 3 3 1 zinc-RING finger domain DUF2158 PF09926.9 KEY74188.1 - 0.068 12.9 0.2 0.068 12.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Dicty_REP PF05086.12 KEY74188.1 - 1.7 6.5 10.0 2.4 6.0 10.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_UBOX PF13445.6 KEY74188.1 - 2.5 8.2 13.2 0.036 14.1 4.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger CDC45 PF02724.14 KEY74188.1 - 9.3 4.4 9.1 14 3.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Mit_KHE1 PF10173.9 KEY74189.1 - 1e-58 198.6 0.0 1.3e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Svf1_C PF17187.4 KEY74190.1 - 1.4e-60 203.9 0.4 3e-60 202.8 0.4 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KEY74190.1 - 1.1e-52 178.4 0.0 1.7e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain HPIH PF13323.6 KEY74190.1 - 0.051 13.4 0.4 0.09 12.6 0.4 1.4 1 0 0 1 1 1 0 N-terminal domain with HPIH motif GATA PF00320.27 KEY74191.1 - 5.9e-15 54.6 3.0 1e-14 53.8 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger CENP-F_leu_zip PF10473.9 KEY74191.1 - 0.0019 18.2 2.1 0.0019 18.2 2.1 2.9 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KEY74191.1 - 0.013 15.7 14.2 0.013 15.7 14.2 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TF_Zn_Ribbon PF08271.12 KEY74191.1 - 0.02 14.4 0.6 0.039 13.5 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4164 PF13747.6 KEY74191.1 - 0.15 12.4 9.9 0.32 11.3 9.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Auto_anti-p27 PF06677.12 KEY74191.1 - 0.17 12.1 0.8 0.27 11.4 0.8 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rogdi_lz PF10259.9 KEY74191.1 - 0.18 11.2 5.0 0.023 14.1 1.1 1.5 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Atg14 PF10186.9 KEY74191.1 - 0.46 9.5 18.5 0.038 13.1 8.7 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A_type_inc PF04508.12 KEY74191.1 - 0.5 10.3 4.5 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IFP_35_N PF07334.13 KEY74191.1 - 0.56 10.3 8.1 0.48 10.5 3.3 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FapA PF03961.13 KEY74191.1 - 0.59 8.7 5.7 0.046 12.3 0.6 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A SHE3 PF17078.5 KEY74191.1 - 0.82 9.3 11.5 0.063 13.0 5.2 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Fmp27_WPPW PF10359.9 KEY74191.1 - 1.8 7.3 14.5 0.088 11.6 6.8 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4094 PF13334.6 KEY74191.1 - 3.1 8.3 10.8 2 8.9 3.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) JIP_LZII PF16471.5 KEY74191.1 - 4.7 7.4 10.8 7.3 6.9 5.0 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ADIP PF11559.8 KEY74191.1 - 5.1 7.2 29.4 0.048 13.7 13.2 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CBFD_NFYB_HMF PF00808.23 KEY74192.1 - 0.055 13.8 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acetyltransf_1 PF00583.25 KEY74193.1 - 2.8e-06 27.6 0.1 4.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 KEY74193.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_15 PF17013.5 KEY74193.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase DUF676 PF05057.14 KEY74195.1 - 1.3e-43 149.0 0.0 3.3e-32 111.8 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) MFS_1 PF07690.16 KEY74196.1 - 8.6e-28 97.3 61.4 6.2e-19 68.1 62.3 4.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MOSC PF03473.17 KEY74199.1 - 4.9e-29 101.0 0.0 8.6e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KEY74199.1 - 1.5e-14 53.9 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain His_Phos_2 PF00328.22 KEY74200.1 - 4.7e-110 368.5 0.1 6.3e-110 368.1 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KEY74200.1 - 4.8e-37 126.0 0.0 1e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KEY74200.1 - 3.8e-06 26.6 0.0 7.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Pap_E4 PF02711.14 KEY74200.1 - 1.7 9.6 17.4 12 6.9 2.4 3.4 2 0 0 2 2 2 0 E4 protein Utp21 PF04192.12 KEY74201.1 - 5.7e-82 274.7 0.0 8.4e-82 274.2 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KEY74201.1 - 6e-16 58.6 25.3 7.9e-06 26.5 0.3 9.1 9 1 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY74201.1 - 1.4e-11 44.5 0.0 0.028 14.7 0.0 5.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KEY74201.1 - 4.2e-06 25.5 0.0 7.7e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 KEY74201.1 - 3.9e-05 22.5 0.0 1.5 7.4 0.0 3.3 2 1 0 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEY74201.1 - 0.004 16.1 0.0 16 4.3 0.0 3.1 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KEY74201.1 - 0.04 12.7 0.1 2.8 6.6 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Methyltr_RsmB-F PF01189.17 KEY74202.1 - 5.4e-32 111.1 0.0 3.4e-24 85.6 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEY74202.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 KEY74203.1 - 4e-40 136.9 0.0 5.3e-30 104.1 0.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KEY74203.1 - 2.3e-23 82.4 0.0 4.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEY74203.1 - 1.4e-07 31.2 0.0 4.7e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KEY74203.1 - 0.024 15.2 0.6 0.051 14.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 KEY74203.1 - 0.027 13.5 0.0 0.98 8.3 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 KEY74203.1 - 0.11 12.3 0.5 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Arf PF00025.21 KEY74203.1 - 0.13 11.7 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran_CTD PF16326.5 KEY74205.1 - 0.00021 21.4 7.4 0.00021 21.4 7.4 5.5 3 2 4 7 7 7 2 ABC transporter C-terminal domain DUF4239 PF14023.6 KEY74205.1 - 0.63 9.7 9.4 0.13 12.0 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) RNA_pol_Rpb5_C PF01191.19 KEY74206.1 - 5.9e-33 112.6 0.2 1.3e-32 111.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KEY74206.1 - 4e-27 94.6 0.1 6.4e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KEY74206.1 - 0.016 15.2 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease TFCD_C PF12612.8 KEY74208.1 - 1.7e-26 93.2 0.2 4.9e-26 91.7 0.2 1.9 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KEY74208.1 - 0.00031 20.8 4.7 2.2 8.8 0.0 6.3 6 1 1 7 7 7 1 HEAT repeat IFRD PF05004.13 KEY74208.1 - 0.017 14.2 2.4 0.039 13.1 2.4 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KEY74208.1 - 0.044 14.4 0.2 1.2 9.8 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KEY74208.1 - 0.057 13.8 10.2 0.1 13.0 0.2 5.1 4 2 0 4 4 4 0 HEAT repeats Glyco_hydro_76 PF03663.14 KEY74209.1 - 9.8e-41 140.5 5.9 2.7e-40 139.0 5.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEY74209.1 - 3.6e-06 26.3 0.4 0.011 14.9 0.0 3.2 2 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KEY74209.1 - 0.04 12.4 0.1 1.5 7.2 0.0 2.4 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 SH3_9 PF14604.6 KEY74211.1 - 8.8e-10 38.3 1.5 2.8e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KEY74211.1 - 0.22 11.2 2.3 0.53 9.9 2.3 1.7 1 0 0 1 1 1 0 SH3 domain Anoctamin PF04547.12 KEY74212.1 - 1.3e-111 373.6 7.1 1.6e-111 373.3 7.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 KEY74213.1 - 3.6e-14 53.7 2.3 6.4e-14 52.9 2.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY74213.1 - 7.6e-06 26.2 0.6 5.7e-05 23.4 0.6 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WSC PF01822.19 KEY74214.1 - 1.6e-08 34.6 3.3 1.6e-08 34.6 3.3 2.6 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.21 KEY74214.1 - 1e-05 25.1 0.0 1e-05 25.1 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KEY74215.1 - 3.3e-63 213.2 0.1 5e-63 212.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY74215.1 - 1.4e-09 37.9 7.5 0.00036 20.8 0.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY74215.1 - 0.00012 22.6 5.9 0.11 13.4 0.3 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KEY74215.1 - 0.13 12.5 2.5 1 9.7 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KEY74215.1 - 0.8 10.3 11.7 0.14 12.7 1.8 3.6 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.6 KEY74216.1 - 2.7e-08 34.0 0.1 2.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_C PF01556.18 KEY74217.1 - 4.7e-39 133.8 0.0 6.8e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEY74217.1 - 1.2e-23 83.0 2.4 2.4e-23 82.0 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEY74217.1 - 1.6e-10 41.2 21.4 3.2e-10 40.2 21.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEY74217.1 - 0.024 14.6 2.8 0.024 14.6 2.8 3.3 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ntox30 PF15532.6 KEY74217.1 - 0.25 11.7 1.3 5.4 7.4 0.2 3.2 3 2 1 4 4 4 0 Bacterial toxin 30 DUF4682 PF15733.5 KEY74217.1 - 1 10.0 4.3 2.1 9.0 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) DnaJ PF00226.31 KEY74218.1 - 8.4e-13 48.2 2.7 1.1e-12 47.9 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain ALMT PF11744.8 KEY74218.1 - 6.1 5.6 7.5 9.2 5.0 7.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.29 KEY74219.1 - 2.2e-48 164.3 0.0 1.8e-47 161.4 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEY74219.1 - 1.2e-24 86.8 0.0 6.3e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KEY74219.1 - 2.3e-21 75.8 1.9 6.2e-21 74.4 1.9 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain FNIP_N PF14636.6 KEY74220.1 - 6.8e-39 134.3 0.0 6.8e-39 134.3 0.0 4.3 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus IML1 PF12257.8 KEY74222.1 - 6e-118 393.1 0.0 8.3e-118 392.6 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KEY74222.1 - 1.5e-26 92.2 0.0 4.2e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.24 KEY74223.1 - 7.2e-47 159.1 36.2 1.4e-25 90.0 16.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Nipped-B_C PF12830.7 KEY74224.1 - 6.2e-52 176.3 1.3 1.4e-49 168.6 0.9 3.0 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KEY74224.1 - 1.2e-06 28.6 3.0 1.4e-06 28.5 0.9 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KEY74224.1 - 0.00024 21.2 0.0 0.0034 17.4 0.0 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEY74224.1 - 0.001 19.1 3.2 0.63 10.5 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat DUF4487 PF14868.6 KEY74224.1 - 0.0042 16.0 0.6 0.0097 14.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) TFIIS_C PF01096.18 KEY74225.1 - 1.9e-13 50.0 0.9 1.9e-13 50.0 0.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KEY74225.1 - 3.2e-05 23.7 2.9 3.2e-05 23.7 2.9 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 KEY74225.1 - 0.0093 15.7 13.5 0.51 10.1 0.1 3.8 4 0 0 4 4 4 2 zinc-ribbon domain UCH_1 PF13423.6 KEY74225.1 - 0.026 14.1 2.6 0.028 14.0 2.6 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.10 KEY74225.1 - 0.079 13.1 6.1 0.7 10.1 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 KEY74225.1 - 0.15 12.0 8.1 0.73 9.9 0.2 2.6 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KEY74225.1 - 0.17 12.2 0.6 0.17 12.2 0.6 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-RING_7 PF02591.15 KEY74225.1 - 0.27 11.5 7.2 9 6.6 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain NOB1_Zn_bind PF08772.11 KEY74225.1 - 0.33 11.2 9.5 3.3 7.9 4.3 2.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L37ae PF01780.19 KEY74225.1 - 0.84 9.8 5.2 0.23 11.6 0.6 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 KEY74225.1 - 0.94 9.4 13.4 0.071 13.1 3.1 2.6 2 2 1 3 3 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KEY74225.1 - 3.8 7.6 13.4 16 5.6 9.9 2.6 2 1 0 2 2 2 0 Double zinc ribbon HEAT_2 PF13646.6 KEY74226.1 - 1.1e-24 86.6 7.0 5.5e-12 45.9 0.2 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KEY74226.1 - 7e-19 66.5 4.3 0.016 15.8 0.0 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KEY74226.1 - 2.8e-06 27.1 3.5 1.3 9.4 0.0 6.1 7 1 1 8 8 8 2 HEAT repeat Arm PF00514.23 KEY74226.1 - 0.0012 18.9 0.7 5.6 7.2 0.1 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEY74226.1 - 0.033 14.7 6.8 1.3 9.6 0.1 4.6 4 1 1 5 5 5 0 HEAT-like repeat AAA_lid_1 PF17857.1 KEY74226.1 - 0.049 13.9 0.1 6.2 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA+ lid domain Cnd1 PF12717.7 KEY74226.1 - 0.05 13.7 0.0 3.7 7.6 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RuvA_C PF07499.13 KEY74226.1 - 2.6 8.6 6.8 5.6 7.5 0.1 3.5 3 0 0 3 3 3 0 RuvA, C-terminal domain ParA PF10609.9 KEY74227.1 - 1.1e-95 319.8 0.0 1.3e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEY74227.1 - 3e-08 33.8 0.0 5.9e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEY74227.1 - 0.00014 21.8 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KEY74227.1 - 0.00058 19.4 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KEY74227.1 - 0.00065 19.0 0.1 0.0022 17.3 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KEY74227.1 - 0.0047 16.5 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KEY74227.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ RsgA_GTPase PF03193.16 KEY74227.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 KEY74227.1 - 0.035 13.9 0.0 4.9 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEY74227.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KEY74227.1 - 0.052 13.9 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KEY74227.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KEY74227.1 - 0.073 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KEY74227.1 - 0.23 11.2 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEY74227.1 - 0.25 11.4 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cofilin_ADF PF00241.20 KEY74228.1 - 1.5e-17 63.5 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 KEY74229.1 - 1.6e-34 118.7 0.0 2.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 KEY74230.1 - 4.3e-59 198.7 0.1 5.1e-59 198.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY74230.1 - 2.3e-20 73.0 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY74230.1 - 2.4e-08 33.6 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY74230.1 - 1.5e-05 24.6 0.1 7.2e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEY74230.1 - 0.00046 20.1 0.2 0.92 9.4 0.1 2.3 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KEY74230.1 - 0.0018 18.3 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KEY74230.1 - 0.0049 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KEY74230.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 KEY74230.1 - 0.14 11.8 0.6 1.8 8.3 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KEY74230.1 - 0.26 11.0 1.2 4 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Acetyltransf_1 PF00583.25 KEY74231.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family YL1 PF05764.13 KEY74231.1 - 0.25 11.4 17.6 0.55 10.3 17.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein 5-FTHF_cyc-lig PF01812.20 KEY74232.1 - 5.1e-28 98.2 0.0 1.6e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.12 KEY74232.1 - 1.1e-25 90.5 0.8 5.7e-25 88.1 0.1 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KEY74232.1 - 0.0002 21.2 0.3 0.00057 19.8 0.3 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KEY74232.1 - 0.0048 16.9 0.0 0.044 13.8 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat Tab2_like PF06485.11 KEY74232.1 - 0.018 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 FAM178 PF14816.6 KEY74232.1 - 0.027 13.5 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 SBDS_C PF09377.10 KEY74232.1 - 0.058 13.4 0.2 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 SBDS protein C-terminal domain OPT PF03169.15 KEY74233.1 - 1.2e-198 661.6 40.2 1.5e-198 661.4 40.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 KEY74233.1 - 0.03 14.3 0.5 0.03 14.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) RPN1_RPN2_N PF17781.1 KEY74234.1 - 7.5e-113 377.0 2.3 1.3e-112 376.2 2.2 1.4 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KEY74234.1 - 1e-29 102.3 0.0 1.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KEY74234.1 - 1.8e-19 69.1 15.2 9.7e-07 28.9 0.1 8.6 9 1 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KEY74234.1 - 1.8e-08 34.7 2.4 0.004 17.5 0.1 4.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KEY74234.1 - 0.071 13.4 0.0 42 4.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat RIO1 PF01163.22 KEY74235.1 - 2.7e-40 138.0 0.5 2.6e-39 134.8 0.5 2.0 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KEY74235.1 - 9e-32 109.1 0.1 2e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KEY74235.1 - 2.4e-07 30.9 0.2 0.0025 17.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEY74235.1 - 9.5e-07 28.4 0.0 0.0084 15.5 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SGT1 PF07093.11 KEY74235.1 - 0.29 9.5 3.5 1.4 7.3 2.5 2.0 2 0 0 2 2 2 0 SGT1 protein CobT PF06213.12 KEY74235.1 - 6.3 6.1 11.7 9.9 5.5 11.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRM_1 PF00076.22 KEY74236.1 - 7.7e-22 76.9 0.0 5.4e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 KEY74237.1 - 8e-61 205.4 0.0 1.2e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEY74237.1 - 3.3e-33 114.9 1.0 6.4e-33 114.0 1.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEY74237.1 - 1.2e-19 70.9 0.0 8.7e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KEY74237.1 - 0.13 12.5 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 KEY74238.1 - 4.3e-218 725.8 0.0 7.7e-218 724.9 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KEY74238.1 - 2.6e-90 302.7 0.0 1.3e-89 300.4 0.0 2.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KEY74238.1 - 7.6e-38 129.9 4.7 5e-17 60.9 0.1 3.6 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 KEY74238.1 - 1.6 9.2 3.7 7.3 7.1 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat DIM1 PF02966.16 KEY74239.1 - 2.3e-69 231.3 0.2 2.6e-69 231.1 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KEY74239.1 - 0.015 15.3 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF2034 PF10356.9 KEY74240.1 - 4e-27 94.8 0.0 1.2e-15 57.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KEY74240.1 - 4.3e-08 33.2 0.0 7.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease GST_N PF02798.20 KEY74241.1 - 3.9e-14 52.7 0.0 8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY74241.1 - 6.7e-14 52.1 0.0 1.4e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY74241.1 - 1.1e-11 44.9 0.1 2.7e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEY74241.1 - 1.3e-11 44.6 0.1 2.1e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY74241.1 - 2.4e-11 43.7 0.1 4.1e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEY74241.1 - 5.9e-09 35.8 0.7 1.4e-08 34.6 0.2 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KEY74241.1 - 8.9e-05 23.2 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KEY74241.1 - 0.0087 16.4 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF2229 PF09989.9 KEY74242.1 - 1.3 8.6 3.1 1.7 8.2 3.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) eIF3_subunit PF08597.10 KEY74242.1 - 3.6 7.4 19.6 0.53 10.2 0.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Lon_C PF05362.13 KEY74243.1 - 3e-66 222.9 0.0 5.2e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KEY74243.1 - 4.4e-33 114.9 0.1 9.8e-33 113.8 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KEY74243.1 - 1.1e-21 77.7 0.0 2.9e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEY74243.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEY74243.1 - 1.8e-06 28.2 0.0 5.7e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KEY74243.1 - 1.7e-05 24.7 0.0 4.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KEY74243.1 - 4.8e-05 23.6 0.0 0.0006 20.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KEY74243.1 - 5.6e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KEY74243.1 - 5.8e-05 22.9 0.1 0.00064 19.5 0.0 2.7 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEY74243.1 - 0.00024 21.5 0.1 0.002 18.5 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KEY74243.1 - 0.012 15.6 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEY74243.1 - 0.015 15.9 0.3 0.081 13.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEY74243.1 - 0.021 14.6 0.0 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KEY74243.1 - 0.036 14.0 0.2 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DNTTIP1_dimer PF18192.1 KEY74243.1 - 0.044 14.1 1.1 1.6 9.1 0.1 3.3 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain RNA_helicase PF00910.22 KEY74243.1 - 0.05 14.0 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KEY74243.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEY74243.1 - 0.09 12.7 0.2 1.6 8.6 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 KEY74243.1 - 0.12 11.9 0.5 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEY74243.1 - 0.26 11.8 1.8 0.9 10.1 0.1 2.6 2 1 0 2 2 2 0 ABC transporter ClpB_D2-small PF10431.9 KEY74243.1 - 0.74 9.9 5.3 0.3 11.2 0.2 2.7 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein Pkinase PF00069.25 KEY74244.1 - 1.9e-12 47.1 0.0 9.7e-11 41.5 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74244.1 - 7.9e-10 38.4 0.0 2.7e-08 33.4 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cyt-b5 PF00173.28 KEY74245.1 - 1.6e-17 63.4 0.4 5.2e-17 61.8 0.0 2.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KEY74245.1 - 2.2e-17 63.8 13.6 2.2e-17 63.8 13.6 1.8 1 1 1 2 2 2 1 Fatty acid desaturase WD40 PF00400.32 KEY74246.1 - 2.9e-09 37.4 4.9 0.00035 21.3 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY74246.1 - 0.0016 18.7 0.1 5.6 7.3 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY74246.1 - 0.0063 15.5 0.0 4 6.3 0.0 2.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 KEY74246.1 - 0.12 12.3 0.0 1 9.2 0.0 2.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Mago-bind PF09282.10 KEY74246.1 - 0.16 11.9 1.3 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Mago binding TFIIB PF00382.19 KEY74247.1 - 0.0016 18.5 0.6 0.061 13.4 0.0 2.9 3 0 0 3 3 3 1 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KEY74247.1 - 0.0032 17.2 0.1 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain MTBP_C PF14920.6 KEY74248.1 - 0.011 15.5 0.8 0.011 15.5 0.8 1.0 1 0 0 1 1 1 0 MDM2-binding BSP PF04450.12 KEY74250.1 - 6.6e-75 251.4 0.0 7.8e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KEY74250.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.8 KEY74251.1 - 7.4e-127 421.5 0.0 1.6e-86 289.6 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KEY74251.1 - 2.7e-05 24.0 0.0 3.3 8.2 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KEY74251.1 - 0.00033 21.0 5.4 2 8.8 0.1 5.0 5 1 1 6 6 6 2 HEAT repeats DRIM PF07539.12 KEY74251.1 - 0.017 13.5 2.0 0.1 10.9 0.8 2.2 2 0 0 2 2 2 0 Down-regulated in metastasis Cnd1 PF12717.7 KEY74251.1 - 0.069 13.2 0.0 3.9 7.5 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RhoGAP PF00620.27 KEY74252.1 - 1.2e-45 155.0 0.7 5.7e-45 152.8 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KEY74252.1 - 1.3e-13 50.9 17.0 4.3e-09 36.5 2.0 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.12 KEY74252.1 - 4.6 6.9 7.6 41 3.9 0.0 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-CHY PF05495.12 KEY74252.1 - 5 7.7 14.8 13 6.4 5.3 2.7 1 1 1 2 2 2 0 CHY zinc finger PRKG1_interact PF15898.5 KEY74252.1 - 6.2 7.8 10.6 12 6.8 0.3 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Cytochrom_CIII PF02085.16 KEY74252.1 - 6.2 7.2 7.6 17 5.8 7.6 1.7 1 0 0 1 1 1 0 Class III cytochrome C family rRNA_processing PF08524.11 KEY74253.1 - 0.0013 18.8 30.1 0.084 12.9 30.1 2.2 1 1 0 1 1 1 1 rRNA processing DUF4407 PF14362.6 KEY74253.1 - 8 5.7 12.1 13 5.1 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KEY74253.1 - 9.2 4.9 11.6 17 4.0 11.6 1.4 1 0 0 1 1 1 0 Presenilin DUF4210 PF13915.6 KEY74254.1 - 8.2e-33 112.8 0.1 2.3e-32 111.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KEY74254.1 - 1e-20 73.6 0.2 2.5e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.6 KEY74255.1 - 2.6e-15 56.3 18.0 9.1e-05 22.6 0.0 8.8 7 2 2 9 9 9 5 PPR repeat family PPR PF01535.20 KEY74255.1 - 2.1e-13 49.6 14.8 0.16 12.3 0.0 10.6 11 0 0 11 11 11 3 PPR repeat TPR_14 PF13428.6 KEY74255.1 - 5.1e-08 33.1 4.4 0.97 10.4 0.0 8.4 8 1 1 9 9 9 1 Tetratricopeptide repeat PPR_3 PF13812.6 KEY74255.1 - 9.8e-08 32.0 0.0 0.46 10.6 0.0 4.6 3 1 2 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KEY74255.1 - 1.4e-06 27.9 1.9 0.00042 19.7 0.3 3.6 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KEY74255.1 - 1.5e-06 27.8 0.1 0.055 13.2 0.0 5.4 5 0 0 5 5 5 1 PPR repeat TPR_4 PF07721.14 KEY74255.1 - 0.011 16.3 0.1 1.2 10.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74255.1 - 0.041 14.4 14.0 5.8 7.5 0.2 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 KEY74256.1 - 2.4e-44 152.1 0.0 3.7e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_25 PF13649.6 KEY74257.1 - 1.2e-14 54.7 0.0 2.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY74257.1 - 2e-13 50.5 0.0 2.6e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74257.1 - 2.6e-12 47.2 0.0 4.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY74257.1 - 2.2e-09 37.3 0.0 2.4e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY74257.1 - 3.2e-08 34.2 0.0 6.5e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY74257.1 - 5.6e-05 22.6 0.0 0.00025 20.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEY74257.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KEY74257.1 - 0.0084 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KEY74257.1 - 0.021 14.2 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KEY74257.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KEY74257.1 - 0.15 12.2 0.0 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase YqeY PF09424.10 KEY74258.1 - 2.8e-24 85.8 7.8 3.3e-24 85.6 7.8 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF2312 PF10073.9 KEY74258.1 - 0.006 16.2 1.1 0.013 15.1 0.7 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) Cucumopine_C PF18631.1 KEY74258.1 - 0.043 13.8 0.0 0.099 12.6 0.0 1.6 1 1 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Ribonuc_L-PSP PF01042.21 KEY74259.1 - 3.8e-26 91.5 0.0 4.6e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1454 PF07305.12 KEY74259.1 - 0.041 13.3 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Sulf_transp PF04143.14 KEY74260.1 - 1.9e-26 93.4 29.4 6.4e-26 91.6 29.4 1.7 1 1 0 1 1 1 1 Sulphur transport Vps55 PF04133.14 KEY74260.1 - 0.036 14.0 0.2 0.036 14.0 0.2 2.1 3 0 0 3 3 3 0 Vacuolar protein sorting 55 ADH_zinc_N PF00107.26 KEY74261.1 - 1.2e-18 67.4 0.1 1.8e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEY74261.1 - 7.3e-08 33.5 0.0 3.1e-07 31.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY74261.1 - 0.00022 21.1 0.0 0.00048 20.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KEY74261.1 - 0.087 12.1 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KH_8 PF17903.1 KEY74262.1 - 3.6e-30 103.9 0.4 8e-30 102.8 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain Pfg27 PF09216.10 KEY74262.1 - 0.033 14.0 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Pfg27 Ribosomal_L11 PF00298.19 KEY74263.1 - 4.2e-28 97.6 0.4 9e-28 96.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KEY74263.1 - 2.8e-24 84.7 0.1 4.2e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 KEY74264.1 - 3.4e-49 167.6 0.0 2.3e-48 164.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Cpn10 PF00166.21 KEY74264.1 - 4.6e-27 93.9 0.0 1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase_Tyr PF07714.17 KEY74264.1 - 2.1e-21 76.4 0.0 4.9e-21 75.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEY74264.1 - 0.0068 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEY74264.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KEY74264.1 - 0.13 11.9 0.1 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KEY74264.1 - 0.2 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_61 PF03443.14 KEY74265.1 - 4e-53 180.4 0.0 5.2e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ras PF00071.22 KEY74266.1 - 4.9e-65 218.1 0.1 5.8e-65 217.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEY74266.1 - 5.7e-34 116.9 0.1 9.7e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEY74266.1 - 2.4e-13 49.9 0.1 2.6e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEY74266.1 - 3.4e-06 26.7 0.0 7.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEY74266.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEY74266.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEY74266.1 - 0.007 16.3 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KEY74266.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KEY74266.1 - 0.083 13.2 0.1 0.71 10.2 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KEY74266.1 - 0.14 12.6 0.0 7.8 6.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KEY74266.1 - 0.14 11.7 0.0 0.69 9.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B HLH PF00010.26 KEY74267.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain AAA PF00004.29 KEY74268.1 - 1.1e-50 171.5 0.0 1.2e-38 132.5 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEY74268.1 - 2.3e-13 49.7 5.5 2e-10 40.3 2.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KEY74268.1 - 6.6e-07 29.9 5.2 0.01 16.2 1.0 4.2 3 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KEY74268.1 - 0.00013 22.0 0.0 0.15 12.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEY74268.1 - 0.00043 20.6 0.0 0.39 11.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KEY74268.1 - 0.00093 19.0 0.0 0.0088 15.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KEY74268.1 - 0.0038 17.2 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KEY74268.1 - 0.0081 16.4 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KEY74268.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 KEY74268.1 - 0.045 14.1 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KEY74268.1 - 0.1 11.9 0.5 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KEY74268.1 - 0.21 11.6 0.0 9.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEY74268.1 - 0.23 11.0 0.0 36 3.8 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region RhlB PF12300.8 KEY74268.1 - 0.29 11.3 4.5 0.11 12.6 1.0 2.1 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB NACHT PF05729.12 KEY74268.1 - 0.36 10.7 4.1 3.7 7.4 0.4 3.1 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 KEY74268.1 - 1.4 8.4 4.2 24 4.4 0.0 3.7 3 1 1 4 4 4 0 AAA domain SMK-1 PF04802.15 KEY74269.1 - 2.8e-81 271.9 1.0 2.8e-81 271.9 1.0 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Glycos_transf_2 PF00535.26 KEY74271.1 - 2.9e-24 85.8 0.0 6.4e-24 84.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEY74271.1 - 1.4e-08 34.9 0.2 8.3e-07 29.1 0.1 2.3 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEY74271.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SE PF08491.10 KEY74272.1 - 4.2e-85 285.1 0.0 5.9e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KEY74272.1 - 9.5e-08 32.0 0.1 7.9e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEY74272.1 - 1.9e-06 27.4 1.0 0.00016 21.0 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEY74272.1 - 0.00023 21.3 0.2 0.00048 20.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY74272.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEY74272.1 - 0.0017 17.5 0.2 0.007 15.5 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KEY74272.1 - 0.0044 17.6 0.1 0.0097 16.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY74272.1 - 0.0078 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEY74272.1 - 0.0088 15.4 0.6 0.012 14.9 0.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KEY74272.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEY74272.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEY74272.1 - 0.056 13.3 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEY74272.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KEY74272.1 - 0.088 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF3482 PF11981.8 KEY74273.1 - 0.046 13.1 0.2 0.084 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Aldo_ket_red PF00248.21 KEY74274.1 - 7.1e-59 199.4 0.1 3.7e-58 197.1 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KEY74276.1 - 3.8e-10 40.2 2.4 0.0064 17.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY74276.1 - 0.0022 18.3 0.0 0.34 11.2 0.0 3.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EIF_2_alpha PF07541.12 KEY74277.1 - 4.2e-34 117.1 0.0 7.6e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KEY74277.1 - 6.2e-15 55.3 0.9 1.3e-14 54.2 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 KEY74277.1 - 0.073 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase family Mito_carr PF00153.27 KEY74278.1 - 2.3e-59 197.3 0.2 2.2e-20 72.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 KEY74278.1 - 0.00017 21.5 0.1 0.00068 19.5 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Ribosomal_L23 PF00276.20 KEY74280.1 - 2.2e-12 47.1 0.0 4.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.14 KEY74281.1 - 4.4e-35 121.1 0.1 6.1e-35 120.7 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Mito_carr PF00153.27 KEY74282.1 - 3.1e-63 209.7 2.6 8.8e-23 80.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEY74282.1 - 0.012 14.8 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease ORC4_C PF14629.6 KEY74283.1 - 5.8e-64 215.5 0.0 8.5e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KEY74283.1 - 4e-13 50.1 0.1 1.1e-12 48.6 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain PHD PF00628.29 KEY74283.1 - 2.1e-11 43.5 7.0 3.5e-11 42.8 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEY74283.1 - 2.2e-10 39.9 2.5 2.2e-10 39.9 2.5 1.6 2 0 0 2 2 1 1 PHD-finger AAA_22 PF13401.6 KEY74283.1 - 6.6e-09 36.2 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEY74283.1 - 9.3e-09 35.8 0.0 2.2e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEY74283.1 - 5.6e-08 32.9 0.0 1.5e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KEY74283.1 - 1.6e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEY74283.1 - 0.00013 22.0 0.0 0.0004 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEY74283.1 - 0.0005 19.3 0.0 0.00079 18.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KEY74283.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEY74283.1 - 0.00065 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KEY74283.1 - 0.00088 19.3 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KEY74283.1 - 0.0018 17.6 0.0 0.004 16.4 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain FYVE_2 PF02318.16 KEY74283.1 - 0.0086 16.3 1.2 0.018 15.2 1.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_18 PF13238.6 KEY74283.1 - 0.01 16.4 0.1 0.095 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KEY74283.1 - 0.013 14.9 0.0 0.29 10.5 0.0 2.2 1 1 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KEY74283.1 - 0.014 15.0 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KEY74283.1 - 0.016 14.8 0.0 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain zf-UDP PF14569.6 KEY74283.1 - 0.024 14.8 2.7 0.049 13.8 2.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger AAA_5 PF07728.14 KEY74283.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEY74283.1 - 0.035 14.5 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KEY74283.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEY74283.1 - 0.045 14.3 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KEY74283.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEY74283.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KEY74283.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 KEY74283.1 - 0.097 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KEY74283.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KEY74283.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.6 KEY74283.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prok-RING_1 PF14446.6 KEY74283.1 - 0.3 11.0 5.5 0.62 10.0 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KEY74283.1 - 0.42 11.0 4.9 0.15 12.4 1.3 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 KEY74283.1 - 1.1 9.2 4.5 2.5 8.0 4.6 1.5 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF2486 PF10667.9 KEY74283.1 - 2.1 8.5 15.3 3.7 7.7 15.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Nop14 PF04147.12 KEY74285.1 - 0.27 9.4 10.4 0.4 8.8 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KEY74285.1 - 4.7 7.0 10.8 0.2 11.5 5.1 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RGS PF00615.19 KEY74286.1 - 5.6e-36 123.4 1.3 2.1e-35 121.5 0.1 2.5 4 0 0 4 4 4 1 Regulator of G protein signaling domain DEP PF00610.21 KEY74286.1 - 2.2e-24 85.3 0.0 8.6e-21 73.8 0.0 3.5 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KEY74286.1 - 0.00043 20.4 0.1 0.077 13.0 0.0 2.4 2 0 0 2 2 2 2 Replication-relaxation CopK PF11525.8 KEY74286.1 - 0.081 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Copper resistance protein K Gly_transf_sug PF04488.15 KEY74288.1 - 2.7e-08 34.3 0.0 7e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KEY74288.1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein CDC73_C PF05179.14 KEY74289.1 - 1.9e-56 190.1 0.0 3e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Bystin PF05291.11 KEY74291.1 - 5.2e-131 436.3 0.0 6.9e-131 435.8 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 KEY74292.1 - 8.7e-67 224.5 0.1 1.6e-65 220.4 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KEY74292.1 - 2.4e-23 81.7 3.0 5.5e-23 80.6 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 KEY74292.1 - 0.00061 20.1 0.2 0.014 15.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats V-ATPase_H_N PF03224.14 KEY74292.1 - 0.017 14.5 0.0 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 V-ATPase subunit H Kelch_5 PF13854.6 KEY74293.1 - 7.7e-12 44.9 1.8 7.7e-12 44.9 1.8 3.9 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KEY74293.1 - 1.1e-05 25.3 3.7 0.63 10.1 0.0 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY74293.1 - 4.6e-05 23.6 0.9 4.6e-05 23.6 0.9 3.7 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KEY74293.1 - 0.0013 18.9 10.2 0.08 13.3 1.6 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KEY74293.1 - 0.005 16.4 3.6 1.2 8.7 2.2 3.1 2 0 0 2 2 2 2 Kelch motif VWA_N PF08399.11 KEY74294.1 - 0.68 10.4 5.2 0.11 13.0 0.6 2.0 2 0 0 2 2 2 0 VWA N-terminal BIR PF00653.21 KEY74295.1 - 2.2e-45 153.2 1.9 3.2e-21 75.8 1.5 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.19 KEY74295.1 - 0.088 12.7 34.2 0.12 12.3 1.5 5.1 5 0 0 5 5 5 0 AT hook motif CoA_binding_2 PF13380.6 KEY74296.1 - 4.7e-16 59.3 0.0 7.8e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 CoA binding domain PAAR_motif PF05488.13 KEY74296.1 - 0.13 12.5 1.1 0.28 11.4 0.7 1.8 1 1 1 2 2 2 0 PAAR motif Methyltransf_11 PF08241.12 KEY74297.1 - 5.9e-19 68.5 0.0 9.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY74297.1 - 5.9e-17 62.2 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY74297.1 - 1.1e-09 38.9 0.0 2.8e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY74297.1 - 3.4e-07 30.2 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY74297.1 - 3.2e-06 26.7 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEY74297.1 - 3.4e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KEY74297.1 - 7.1e-06 25.3 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 KEY74297.1 - 8.1e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KEY74297.1 - 0.0046 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KEY74297.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.15 KEY74297.1 - 0.066 13.0 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Mn_catalase PF05067.12 KEY74297.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase Calpain_inhib PF00748.19 KEY74297.1 - 0.2 12.1 0.0 0.61 10.6 0.0 1.7 2 0 0 2 2 2 0 Calpain inhibitor Peptidase_M3 PF01432.20 KEY74298.1 - 2.8e-149 498.3 0.0 3.6e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 EF-hand_7 PF13499.6 KEY74298.1 - 1.1e-10 41.8 0.1 8.4e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KEY74298.1 - 2.5e-10 40.5 0.0 7.7e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KEY74298.1 - 1.9e-06 27.3 1.0 0.1 12.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEY74298.1 - 7.2e-06 25.2 0.0 0.27 10.9 0.0 3.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KEY74298.1 - 0.00036 20.3 0.1 0.006 16.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3770 PF12603.8 KEY74298.1 - 0.12 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Peptidase_M91 PF14891.6 KEY74298.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Effector protein MFS_1 PF07690.16 KEY74299.1 - 7.8e-29 100.7 34.9 7.8e-29 100.7 34.9 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily 7tm_2 PF00002.24 KEY74300.1 - 4.7e-09 35.9 10.5 4.7e-09 35.9 10.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KEY74300.1 - 1.5e-08 34.3 5.0 2e-08 33.9 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KEY74300.1 - 0.014 15.2 13.3 0.024 14.4 13.3 1.3 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 L6_membrane PF05805.12 KEY74300.1 - 0.029 14.0 2.7 0.089 12.4 2.7 1.8 1 1 0 1 1 1 0 L6 membrane protein WBP-1 PF11669.8 KEY74300.1 - 0.39 11.4 2.3 2.4 8.8 2.3 2.4 1 1 0 1 1 1 0 WW domain-binding protein 1 MFS_1 PF07690.16 KEY74301.1 - 8.7e-11 41.3 34.7 8.7e-11 41.3 34.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF5357 PF17310.2 KEY74301.1 - 0.26 9.8 4.3 0.52 8.8 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5357) F-box-like PF12937.7 KEY74302.1 - 3.6e-05 23.6 1.7 0.00011 22.1 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KEY74302.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box Sulfate_transp PF00916.20 KEY74303.1 - 2.5e-102 342.5 22.5 3.3e-102 342.1 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEY74303.1 - 3.4e-10 39.6 0.0 6.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain DUF996 PF06195.13 KEY74303.1 - 0.0093 16.3 1.6 0.0093 16.3 1.6 3.7 3 2 0 3 3 3 1 Protein of unknown function (DUF996) DUF5592 PF17332.2 KEY74303.1 - 0.19 12.3 2.5 0.2 12.2 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Glyco_transf_22 PF03901.17 KEY74304.1 - 1.9e-84 284.3 17.6 2.2e-84 284.1 17.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KEY74305.1 - 1.1e-47 161.6 0.1 1.1e-47 161.6 0.1 1.9 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Peptidase_M28 PF04389.17 KEY74306.1 - 6.6e-30 104.3 0.2 1.1e-29 103.5 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY74306.1 - 5.1e-06 26.3 0.3 1.1e-05 25.3 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Sld5 PF05916.11 KEY74308.1 - 1.3e-28 99.6 0.0 3.6e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 GINS complex protein Fungal_trans_2 PF11951.8 KEY74308.1 - 0.031 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Caskin-Pro-rich PF16907.5 KEY74308.1 - 4 8.0 10.1 6.4 7.4 0.6 2.8 3 0 0 3 3 3 0 Proline rich region of Caskin proteins Acetyltransf_9 PF13527.7 KEY74309.1 - 4.6e-05 23.5 0.1 9.8e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY74309.1 - 0.0031 17.9 0.1 0.0089 16.4 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEY74309.1 - 0.026 14.5 0.1 0.076 12.9 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ProRS-C_1 PF09180.11 KEY74310.1 - 6.9e-23 80.6 0.1 1.3e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KEY74310.1 - 5e-19 68.9 0.0 8.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEY74310.1 - 3.4e-15 56.0 0.0 1.1e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain MT0933_antitox PF14013.6 KEY74310.1 - 0.36 11.2 6.4 1.2 9.5 6.4 1.9 1 0 0 1 1 1 0 MT0933-like antitoxin protein Cpn60_TCP1 PF00118.24 KEY74311.1 - 8.1e-151 503.0 11.8 9.2e-151 502.8 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Euplotes_phero PF05842.11 KEY74312.1 - 8.7 6.9 9.7 1.5 9.4 3.8 2.2 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein Rieske PF00355.26 KEY74313.1 - 2.1e-11 43.6 0.0 3.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KEY74313.1 - 2.4e-08 34.3 2.6 5.8e-08 33.1 1.9 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.9 KEY74314.1 - 6.1e-117 391.2 0.0 1.1e-116 390.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEY74314.1 - 1.8e-65 221.4 0.0 7.7e-65 219.3 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region RNA_pol_Rpb4 PF03874.16 KEY74315.1 - 0.048 14.0 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 R3H-assoc PF13902.6 KEY74316.1 - 1.5e-25 90.2 3.8 1.5e-25 90.2 3.8 1.7 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 KEY74316.1 - 8.4e-05 22.5 0.1 0.00031 20.7 0.0 1.9 2 0 0 2 2 2 1 R3H domain CCD48 PF15799.5 KEY74316.1 - 0.02 13.2 1.5 0.033 12.5 1.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 PQ-loop PF04193.14 KEY74317.1 - 4.8e-22 77.5 17.0 1.7e-13 50.2 0.9 3.5 3 1 1 4 4 4 2 PQ loop repeat MtN3_slv PF03083.16 KEY74317.1 - 0.045 13.8 1.1 0.3 11.2 0.1 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF1129 PF06570.11 KEY74317.1 - 3.1 7.3 5.9 0.39 10.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2975 PF11188.8 KEY74317.1 - 7.8 6.4 9.2 0.42 10.5 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) HTH_32 PF13565.6 KEY74319.1 - 0.012 16.3 0.3 0.017 15.7 0.1 1.4 1 1 1 2 2 2 0 Homeodomain-like domain Nitrate_red_gam PF02665.14 KEY74320.1 - 0.026 14.1 0.5 0.045 13.3 0.5 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 KEY74320.1 - 0.13 12.2 0.8 0.41 10.6 0.8 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Plasmodium_Vir PF05795.11 KEY74320.1 - 0.33 10.3 0.8 0.42 10.0 0.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.6 KEY74320.1 - 1 9.3 10.4 0.035 14.0 2.7 2.0 1 1 1 2 2 2 0 TMEM154 protein family Hamartin PF04388.12 KEY74320.1 - 4.7 5.8 9.2 6.4 5.3 9.2 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_transf_28 PF03033.20 KEY74321.1 - 4.9e-25 88.2 0.0 9.7e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KEY74321.1 - 0.00038 19.4 0.0 0.00066 18.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KEY74321.1 - 0.12 12.2 0.3 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal CF222 PF15661.5 KEY74321.1 - 0.34 9.8 0.8 0.5 9.2 0.8 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family Ion_trans PF00520.31 KEY74322.1 - 1.9e-06 27.3 25.0 4.3e-06 26.1 25.0 1.6 1 1 0 1 1 1 1 Ion transport protein PNTB_4TM PF12769.7 KEY74322.1 - 0.0027 18.1 0.2 0.0089 16.5 0.2 1.9 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Cellulase PF00150.18 KEY74323.1 - 2.6e-11 43.5 0.0 8.7e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SH3_1 PF00018.28 KEY74325.1 - 1.6e-27 94.8 0.0 9.9e-14 50.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KEY74325.1 - 3e-19 68.6 0.1 5.9e-10 38.8 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KEY74325.1 - 1.6e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KEY74325.1 - 2.4e-12 46.4 0.0 2.6e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KEY74325.1 - 7.1e-09 35.5 0.1 1.3e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 KEY74325.1 - 0.043 13.7 0.1 1.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SAC3_GANP PF03399.16 KEY74326.1 - 1.2e-22 80.6 3.3 1.3e-20 74.0 3.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family EAP30 PF04157.16 KEY74327.1 - 7.5e-42 143.2 0.0 1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KEY74327.1 - 2.6e-23 82.0 0.0 4.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KEY74327.1 - 2.4e-22 78.1 2.1 2.4e-22 78.1 2.1 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KEY74327.1 - 0.00037 19.7 1.0 0.00037 19.7 1.0 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KEY74327.1 - 0.0044 17.0 5.2 0.068 13.2 0.3 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.20 KEY74327.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DZR PF12773.7 KEY74327.1 - 0.31 11.1 4.5 0.11 12.5 0.6 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 KEY74327.1 - 0.34 10.8 1.7 0.89 9.5 1.7 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C2H2_4 PF13894.6 KEY74327.1 - 5.6 8.1 8.1 22 6.2 0.7 3.7 2 1 1 3 3 3 0 C2H2-type zinc finger HTH_ABP1_N PF18107.1 KEY74328.1 - 1.4e-23 82.4 3.0 3.3e-23 81.1 3.0 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 KEY74328.1 - 2.6e-17 62.6 0.3 1.8e-16 59.9 0.1 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SGL PF08450.12 KEY74328.1 - 1.4e-16 60.8 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KEY74328.1 - 0.013 15.5 2.3 9.7 6.4 0.0 4.0 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 KEY74328.1 - 0.022 14.9 0.1 8.6 7.0 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Cep57_CLD_2 PF14197.6 KEY74328.1 - 0.035 14.2 2.3 0.07 13.2 2.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 KEY74328.1 - 0.053 14.0 0.6 0.088 13.3 0.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ATP19 PF11022.8 KEY74329.1 - 1.2e-28 99.3 0.0 1.3e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 KEY74330.1 - 1.4e-82 275.8 0.1 1.8e-82 275.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 KEY74331.1 - 9.9e-25 86.4 25.5 1.6e-12 47.3 7.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KEY74331.1 - 0.015 15.5 5.1 0.015 15.5 5.1 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KEY74331.1 - 0.097 13.0 13.5 1.2 9.5 4.3 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.15 KEY74332.1 - 4.2e-31 107.6 0.8 1.6e-30 105.8 0.8 2.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KEY74332.1 - 3.1e-27 94.8 0.9 7.3e-27 93.6 0.4 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KEY74332.1 - 1.5e-20 72.7 0.6 3.9e-20 71.4 0.6 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KEY74332.1 - 2e-15 57.5 1.6 2e-15 57.5 1.6 5.7 6 1 0 6 6 6 2 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KEY74332.1 - 0.013 15.9 0.0 0.17 12.4 0.0 2.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily BTB PF00651.31 KEY74333.1 - 0.012 15.8 0.0 0.16 12.2 0.0 2.3 1 1 0 1 1 1 0 BTB/POZ domain Dcc1 PF09724.9 KEY74334.1 - 3.6e-11 42.9 0.1 4.2e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 V-ATPase_H_C PF11698.8 KEY74334.1 - 0.062 13.4 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H RhoGEF PF00621.20 KEY74335.1 - 2.4e-26 93.1 0.6 4.8e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KEY74335.1 - 0.0032 17.2 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KEY74335.1 - 0.1 12.8 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 Phi-29_GP16_7 PF06720.11 KEY74335.1 - 0.11 12.4 0.2 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 WXG100 PF06013.12 KEY74335.1 - 0.15 12.3 1.1 0.96 9.7 0.2 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG ATG16 PF08614.11 KEY74335.1 - 0.16 12.2 22.3 0.022 15.0 5.0 3.9 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 KEY74335.1 - 0.59 9.5 11.6 0.19 11.1 5.4 2.4 1 1 1 2 2 2 0 Rabaptin-like protein ING PF12998.7 KEY74335.1 - 2.4 8.8 8.9 3.4 8.3 0.4 3.7 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Seryl_tRNA_N PF02403.22 KEY74335.1 - 4.7 7.5 13.7 2.2 8.5 7.2 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HORMA PF02301.18 KEY74336.1 - 3.5e-11 43.1 0.0 4.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.8 KEY74337.1 - 1.8e-57 193.7 0.0 3.2e-57 192.9 0.0 1.4 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KEY74337.1 - 1.7e-18 67.5 17.8 1.7e-18 67.5 17.8 2.4 3 0 0 3 3 3 1 PI31 proteasome regulator HTH_56 PF18662.1 KEY74337.1 - 0.15 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Cch helix turn helix domain IBN_N PF03810.19 KEY74338.1 - 2e-09 37.2 1.3 7.6e-09 35.4 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KEY74338.1 - 0.0006 19.9 0.1 0.0049 16.9 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KEY74338.1 - 0.024 13.1 0.0 0.046 12.2 0.0 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus T_cell_tran_alt PF15128.6 KEY74339.1 - 0.049 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Phage_holin_5_2 PF16079.5 KEY74339.1 - 4.2 7.8 13.3 2.7 8.4 0.6 3.3 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF3147 PF11345.8 KEY74339.1 - 4.3 7.8 17.2 2.2 8.7 3.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3147) TraP PF07296.11 KEY74339.1 - 4.9 6.3 8.5 0.27 10.4 3.0 1.6 2 0 0 2 2 2 0 TraP protein Transp_cyt_pur PF02133.15 KEY74340.1 - 2.1e-152 508.0 35.1 2.4e-152 507.8 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1146 PF06612.11 KEY74340.1 - 0.16 12.0 4.8 11 6.2 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) Fungal_trans_2 PF11951.8 KEY74341.1 - 1.4e-29 103.1 0.0 1.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74341.1 - 6.9e-06 26.1 9.0 1.2e-05 25.3 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Egh16-like PF11327.8 KEY74342.1 - 6.1e-65 219.1 10.2 9.1e-65 218.5 10.2 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor TMA7 PF09072.10 KEY74342.1 - 0.065 14.1 1.6 0.16 12.8 1.6 1.6 1 0 0 1 1 1 0 Translation machinery associated TMA7 Metallophos PF00149.28 KEY74344.1 - 4.1e-36 125.4 0.4 5.2e-36 125.1 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEY74344.1 - 0.036 14.5 0.2 0.094 13.2 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 KEY74345.1 - 1.6e-66 223.8 0.4 1.7e-66 223.7 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 KEY74345.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.7 1 1 0 1 1 1 0 ML domain Ribosomal_S16 PF00886.19 KEY74345.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein S16 Kelch_5 PF13854.6 KEY74346.1 - 3.2e-08 33.4 11.2 3.9e-07 29.9 0.1 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 KEY74346.1 - 0.001 19.0 10.7 0.016 15.2 0.1 5.1 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KEY74346.1 - 0.019 14.9 1.7 14 5.8 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 KEY74346.1 - 0.026 14.8 4.0 7.7 7.0 0.0 4.2 4 0 0 4 4 4 0 Kelch motif CcmD PF04995.14 KEY74346.1 - 0.1 12.7 3.0 0.21 11.7 3.0 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Glyco_hydro_3_C PF01915.22 KEY74347.1 - 8e-35 120.6 0.0 1.9e-34 119.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY74347.1 - 2.4e-28 99.4 0.0 7.2e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY74347.1 - 1.2e-22 79.7 0.1 2.9e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Epimerase PF01370.21 KEY74348.1 - 9.6e-12 44.9 0.0 3e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY74348.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEY74348.1 - 8.8e-05 22.1 0.2 0.00024 20.6 0.2 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY74348.1 - 0.00021 20.4 0.1 0.00056 19.0 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEY74348.1 - 0.00076 18.7 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KEY74348.1 - 0.0054 16.3 0.1 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NARG2_C PF10505.9 KEY74352.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus F-box-like PF12937.7 KEY74355.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KEY74355.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF3435 PF11917.8 KEY74357.1 - 7.7e-55 186.5 0.0 1.1e-54 186.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) GATA PF00320.27 KEY74359.1 - 0.067 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 GATA zinc finger Glyco_hydro_61 PF03443.14 KEY74360.1 - 6.3e-39 134.0 0.0 7.7e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Asparaginase PF00710.20 KEY74363.1 - 1.3e-27 96.6 0.1 3.8e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEY74363.1 - 3.3e-20 72.4 0.1 9e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Peptidase_C2 PF00648.21 KEY74364.1 - 4e-17 62.2 0.0 6.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C1 PF00112.23 KEY74364.1 - 0.041 14.0 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 Papain family cysteine protease Ank_2 PF12796.7 KEY74365.1 - 2.7e-35 120.8 3.6 3.1e-14 53.3 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74365.1 - 1.7e-23 82.6 0.0 5.2e-09 36.5 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY74365.1 - 9.9e-21 73.2 2.7 0.00045 20.6 0.1 4.9 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KEY74365.1 - 3.4e-20 70.0 0.0 0.003 17.9 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KEY74365.1 - 8.4e-14 51.5 0.1 0.00012 22.3 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Fructosamin_kin PF03881.14 KEY74365.1 - 0.025 13.8 0.1 0.09 12.0 0.1 1.8 2 0 0 2 2 2 0 Fructosamine kinase VWA_3_C PF18571.1 KEY74365.1 - 1.1 9.2 4.8 9.3 6.2 0.0 3.8 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain PH_TFIIH PF08567.11 KEY74366.1 - 0.0078 16.5 0.0 0.026 14.9 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain SlyX PF04102.12 KEY74366.1 - 0.039 14.6 0.7 0.039 14.6 0.7 1.8 2 0 0 2 2 2 0 SlyX FAD_binding_3 PF01494.19 KEY74368.1 - 8.2e-10 38.4 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 KEY74369.1 - 0.00015 21.3 0.0 0.00031 20.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase DUF1877 PF08974.10 KEY74369.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) adh_short_C2 PF13561.6 KEY74370.1 - 1.9e-27 96.3 0.1 1.9e-17 63.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY74370.1 - 4.5e-23 81.7 0.1 7.6e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY74370.1 - 0.014 15.3 0.3 0.05 13.5 0.0 2.2 2 1 0 2 2 2 0 KR domain Transferase PF02458.15 KEY74372.1 - 3.3e-07 29.3 0.0 0.00011 21.0 0.0 2.1 2 0 0 2 2 2 2 Transferase family LIP PF03583.14 KEY74373.1 - 1.7e-55 188.4 0.0 2.5e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase FAD_binding_3 PF01494.19 KEY74374.1 - 2.4e-17 63.2 7.8 8.9e-16 58.1 7.8 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY74374.1 - 2.8e-06 27.2 1.2 4.1e-06 26.6 1.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY74374.1 - 0.00029 21.0 0.5 0.00085 19.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY74374.1 - 0.0013 19.3 2.1 0.0027 18.2 2.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY74374.1 - 0.0059 15.9 0.1 0.0095 15.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEY74374.1 - 0.029 14.3 0.4 0.049 13.5 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEY74374.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KEY74374.1 - 0.12 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 KEY74374.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEY74374.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KEY74374.1 - 0.17 12.5 0.2 0.37 11.4 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ketoacyl-synt PF00109.26 KEY74375.1 - 3.8e-66 223.2 0.3 8.6e-66 222.1 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY74375.1 - 2.9e-28 98.3 0.0 9.3e-28 96.6 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KEY74375.1 - 8.8e-28 97.2 0.0 1.4e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein HTH_51 PF18558.1 KEY74375.1 - 3.6e-27 94.1 0.0 6.2e-26 90.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KEY74375.1 - 5.1e-24 85.3 0.1 3.9e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KEY74375.1 - 6e-14 52.4 1.7 5.5e-08 32.8 0.2 4.1 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KEY74375.1 - 5.4e-12 46.3 0.0 1.7e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEY74375.1 - 2.2e-11 43.9 0.9 9.8e-11 41.9 0.5 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KEY74375.1 - 2.7e-10 40.3 0.0 2.9e-09 37.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY74375.1 - 4.9e-09 36.8 0.0 1.7e-08 35.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74375.1 - 7.4e-08 32.9 0.0 2.5e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEY74375.1 - 1.4e-06 28.0 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 KEY74375.1 - 5.9e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEY74375.1 - 0.00027 20.4 0.0 0.00087 18.7 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KEY74375.1 - 0.0024 18.3 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 KEY74375.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FlgT_M PF16539.5 KEY74375.1 - 0.082 13.0 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain Semialdhyde_dh PF01118.24 KEY74375.1 - 0.12 12.9 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1638 PF07796.11 KEY74376.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Ank_2 PF12796.7 KEY74377.1 - 3e-63 210.4 2.2 1.6e-10 41.4 0.0 11.5 3 3 6 12 12 12 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74377.1 - 4e-45 151.6 8.3 2.9e-06 27.7 0.1 13.8 10 2 4 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY74377.1 - 4.3e-34 116.1 14.9 6.5e-05 23.1 0.3 14.8 11 4 5 16 16 16 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74377.1 - 7.9e-33 108.8 15.0 0.018 15.6 0.0 17.3 18 0 0 18 18 18 7 Ankyrin repeat Ank PF00023.30 KEY74377.1 - 1.2e-25 88.7 20.5 0.0041 17.5 0.0 14.8 17 0 0 17 17 17 6 Ankyrin repeat XPC-binding PF09280.11 KEY74377.1 - 0.76 9.6 3.9 5.3 6.9 3.9 2.5 1 0 0 1 1 1 0 XPC-binding domain Peptidase_S8 PF00082.22 KEY74378.1 - 3.8e-11 42.8 0.1 1.1e-10 41.2 0.1 1.7 1 1 0 1 1 1 1 Subtilase family Ank PF00023.30 KEY74378.1 - 0.021 15.2 0.1 5.8 7.5 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeat Abhydrolase_6 PF12697.7 KEY74380.1 - 0.0015 19.2 0.1 0.0017 19.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY74380.1 - 0.0037 17.0 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KEY74380.1 - 0.031 13.6 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase Chlorophyllase PF07224.11 KEY74380.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Chlorophyllase NmrA PF05368.13 KEY74381.1 - 4.8e-20 72.1 0.3 5.1e-19 68.7 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74381.1 - 3.9e-06 26.9 0.1 6.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEY74381.1 - 0.011 14.8 0.1 0.099 11.6 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ABC2_membrane PF01061.24 KEY74382.1 - 9.6e-82 273.5 39.4 8.5e-45 152.8 15.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY74382.1 - 1.1e-37 129.6 0.0 3.5e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY74382.1 - 1.2e-27 95.6 0.2 1e-22 79.8 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEY74382.1 - 4.9e-18 65.3 24.4 2.7e-12 46.5 3.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KEY74382.1 - 5.8e-10 39.7 0.1 1.9e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY74382.1 - 4.3e-05 24.0 0.2 0.02 15.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KEY74382.1 - 8.6e-05 22.2 0.1 0.02 14.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY74382.1 - 0.00026 21.0 0.3 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KEY74382.1 - 0.00028 21.4 0.1 0.64 10.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KEY74382.1 - 0.00042 20.0 0.1 0.064 13.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY74382.1 - 0.0019 18.5 0.0 0.55 10.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KEY74382.1 - 0.0028 17.8 0.0 0.81 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEY74382.1 - 0.0036 17.6 1.5 0.18 12.1 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEY74382.1 - 0.006 16.4 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KEY74382.1 - 0.025 14.2 1.8 3.4 7.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEY74382.1 - 0.035 14.0 0.4 2.2 8.2 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KEY74382.1 - 0.073 12.8 1.0 3.3 7.4 0.4 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KEY74382.1 - 0.12 12.1 0.8 8.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KEY74382.1 - 0.19 11.8 0.3 17 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 KEY74382.1 - 0.39 9.9 15.6 0.013 14.8 6.1 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Zn_clus PF00172.18 KEY74383.1 - 5.9e-05 23.1 11.5 0.00012 22.1 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.19 KEY74383.1 - 0.23 11.5 4.2 3.9 7.5 3.8 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NmrA PF05368.13 KEY74384.1 - 1.6e-21 77.0 0.0 2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74384.1 - 1.7e-16 60.7 0.0 3.6e-16 59.6 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEY74384.1 - 7.1e-05 22.4 0.0 0.00017 21.1 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY74384.1 - 0.016 14.3 0.0 0.05 12.6 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Formyl_trans_N PF00551.19 KEY74384.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase NmrA PF05368.13 KEY74385.1 - 2.5e-37 128.7 0.0 3.9e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74385.1 - 1.7e-11 44.3 0.0 2.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY74385.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEY74385.1 - 0.054 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Aft1_HRA PF11786.8 KEY74385.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Aft1 HRA domain DUF4267 PF14087.6 KEY74386.1 - 4.1e-15 55.8 4.6 5.5e-15 55.4 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) adh_short PF00106.25 KEY74387.1 - 2e-25 89.4 0.2 5.1e-24 84.8 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74387.1 - 7e-20 71.6 0.0 1.9e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74387.1 - 0.00057 19.8 0.6 0.0011 19.0 0.6 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74387.1 - 0.03 13.8 0.3 0.087 12.3 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 KEY74388.1 - 1.9e-32 112.5 0.3 2.5e-32 112.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEY74389.1 - 3.4e-30 105.1 35.1 4.8e-30 104.7 35.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KEY74390.1 - 7.4e-42 143.5 0.3 9.3e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 KEY74391.1 - 3.1e-05 24.3 0.1 4.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KEY74391.1 - 0.0022 16.8 0.0 0.018 13.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) Pkinase PF00069.25 KEY74392.1 - 3.7e-25 88.8 0.0 1.9e-14 53.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74392.1 - 3e-08 33.3 0.0 0.0059 15.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KEY74392.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEY74392.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HET PF06985.11 KEY74393.1 - 1.1e-27 97.2 0.0 2e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Musclin PF11037.8 KEY74393.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle GST_N_3 PF13417.6 KEY74394.1 - 6.2e-16 58.6 0.0 1.9e-15 57.0 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEY74394.1 - 2.6e-15 56.5 0.0 4.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY74394.1 - 6.4e-12 45.6 0.1 1.6e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Fungal_trans_2 PF11951.8 KEY74395.1 - 3.5e-05 22.8 0.2 5.7e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_5 PF13857.6 KEY74396.1 - 0.026 14.8 0.0 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY74396.1 - 0.099 13.3 0.0 19 6.0 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HET PF06985.11 KEY74398.1 - 6.9e-14 52.4 6.3 1.9e-11 44.5 0.2 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) M3 PF09213.10 KEY74398.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 M3 adh_short PF00106.25 KEY74399.1 - 1.7e-22 79.8 0.0 2.1e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY74399.1 - 3.7e-08 33.5 0.1 5.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY74399.1 - 9.4e-06 25.3 0.0 2.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase OPT PF03169.15 KEY74400.1 - 9.1e-116 387.9 47.5 1.1e-115 387.7 47.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_4 PF01565.23 KEY74401.1 - 2.1e-17 63.2 1.3 9.7e-17 61.0 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY74401.1 - 2.8e-05 24.1 0.2 2.8e-05 24.1 0.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like GARS_N PF02844.15 KEY74401.1 - 0.12 13.2 0.0 0.44 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Pectate_lyase PF03211.13 KEY74402.1 - 2.2e-84 282.1 9.0 2.5e-84 281.9 9.0 1.0 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_61 PF03443.14 KEY74403.1 - 2.9e-52 177.6 0.0 3.6e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 KEY74403.1 - 0.0032 17.9 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 MG2 domain He_PIG PF05345.12 KEY74403.1 - 0.12 12.6 2.6 5 7.4 0.0 3.5 3 0 0 3 3 3 0 Putative Ig domain MFS_1 PF07690.16 KEY74405.1 - 0.093 11.6 47.3 0.029 13.3 23.4 3.1 1 1 2 3 3 3 0 Major Facilitator Superfamily Metallothio_Pro PF02069.16 KEY74407.1 - 0.0053 17.0 0.1 0.0057 16.9 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic metallothionein DDE_Tnp_1_7 PF13843.6 KEY74408.1 - 4.6e-15 55.8 0.0 8.3e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 Transposase IS4 DUF957 PF06117.11 KEY74409.1 - 0.049 13.2 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) rve PF00665.26 KEY74410.1 - 8.1e-14 51.8 0.0 2.1e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KEY74410.1 - 0.069 12.9 0.2 0.36 10.6 0.2 2.3 1 1 0 1 1 1 0 Integrase core domain Pectate_lyase PF03211.13 KEY74411.1 - 1.3e-75 253.4 6.3 1.6e-75 253.1 6.3 1.1 1 0 0 1 1 1 1 Pectate lyase HET PF06985.11 KEY74412.1 - 1.1e-30 106.9 0.4 1.6e-25 90.2 0.1 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 KEY74413.1 - 2.1e-09 37.6 0.0 2.2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Helo_like_N PF17111.5 KEY74414.1 - 3.6e-73 245.4 11.1 1.8e-72 243.1 3.0 2.4 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SLATT_5 PF18160.1 KEY74414.1 - 0.0043 16.4 1.9 0.0057 16.0 0.2 2.0 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 GlutR_dimer PF00745.20 KEY74414.1 - 0.023 15.2 4.4 0.032 14.7 0.7 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain PilJ PF13675.6 KEY74414.1 - 0.042 13.9 4.4 0.48 10.5 0.2 3.2 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DMPK_coil PF08826.10 KEY74414.1 - 1.2 9.3 5.4 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 DMPK coiled coil domain like Cep57_CLD_2 PF14197.6 KEY74414.1 - 1.2 9.3 6.0 14 5.9 0.2 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 WSC PF01822.19 KEY74417.1 - 3.9e-09 36.6 2.7 3.9e-09 36.6 2.7 1.9 2 0 0 2 2 2 1 WSC domain Ribonuc_L-PSP PF01042.21 KEY74418.1 - 3.1e-17 62.7 0.1 5.3e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP SPATA19 PF15212.6 KEY74418.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Glyco_hydro_3_C PF01915.22 KEY74419.1 - 8.7e-37 127.1 0.0 2.3e-36 125.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY74419.1 - 5.2e-28 98.3 0.0 8.8e-25 87.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY74419.1 - 6.7e-25 87.0 0.1 1.3e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3425 PF11905.8 KEY74420.1 - 1.2e-21 77.0 0.1 2.8e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.21 KEY74421.1 - 1.1e-58 198.7 0.0 2e-58 198.0 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KEY74422.1 - 1.4e-26 93.2 0.0 8.8e-26 90.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74422.1 - 1.6e-16 60.6 0.0 6.2e-16 58.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74422.1 - 4.7e-06 26.6 0.1 7.1e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74422.1 - 0.0075 15.8 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY74422.1 - 0.034 13.6 0.0 7.7 5.8 0.0 2.7 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KEY74423.1 - 1e-17 64.1 0.0 2.6e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEY74424.1 - 3.5e-87 293.1 0.0 3.4e-66 223.9 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 FGase PF05013.12 KEY74424.1 - 0.048 13.9 0.1 0.087 13.0 0.1 1.4 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase ADH_zinc_N_2 PF13602.6 KEY74425.1 - 1.5e-12 48.7 0.1 3.7e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY74425.1 - 2.1e-11 43.9 0.0 5.1e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cupin_2 PF07883.11 KEY74426.1 - 7.8e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEY74426.1 - 0.0023 17.6 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KEY74426.1 - 0.036 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Glyco_hydro_61 PF03443.14 KEY74428.1 - 1.1e-55 188.8 0.0 1.3e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2263 PF10021.9 KEY74429.1 - 2.2e-19 70.3 0.0 5.4e-19 69.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF1690 PF07956.11 KEY74429.1 - 0.011 16.1 0.8 0.025 15.0 0.8 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Macro PF01661.21 KEY74429.1 - 0.12 12.4 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Macro domain G_path_suppress PF15991.5 KEY74429.1 - 1.8 8.6 7.1 3.2 7.8 7.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor SMI1_KNR4 PF09346.10 KEY74432.1 - 1.4e-07 32.0 0.0 3.4e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KEY74432.1 - 1.1e-05 25.8 0.0 2.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 KEY74432.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall DUF4345 PF14248.6 KEY74433.1 - 0.094 12.6 5.3 0.21 11.5 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) FA_desaturase PF00487.24 KEY74433.1 - 0.59 9.9 5.3 1.2 9.0 5.3 1.5 1 0 0 1 1 1 0 Fatty acid desaturase MFS_1 PF07690.16 KEY74434.1 - 2.5e-10 39.8 8.0 2.9e-10 39.6 8.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY74434.1 - 0.00031 19.7 1.2 0.0005 19.1 1.0 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY74435.1 - 3.8e-26 91.8 9.7 3.8e-26 91.8 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY74435.1 - 0.017 13.6 1.6 0.02 13.3 0.1 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HET PF06985.11 KEY74436.1 - 1.5e-35 122.7 0.6 2.9e-35 121.8 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KEY74437.1 - 1.4e-05 25.1 0.1 3.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY74437.1 - 0.0014 19.1 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PTPA PF03095.15 KEY74437.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Abhydrolase_3 PF07859.13 KEY74439.1 - 4.9e-45 154.0 0.0 6.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY74439.1 - 2.2e-12 46.7 0.6 1.1e-11 44.3 0.6 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KEY74439.1 - 0.0003 21.5 0.5 0.00044 20.9 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HhH-GPD PF00730.25 KEY74441.1 - 3.5e-11 43.5 0.0 6.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2040 PF09745.9 KEY74441.1 - 0.14 12.2 0.1 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Epimerase PF01370.21 KEY74442.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEY74442.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.22 KEY74443.1 - 1.5e-59 202.0 0.0 1.8e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KEY74444.1 - 1.1e-21 77.1 0.1 2e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74444.1 - 7.4e-06 26.0 11.1 1.4e-05 25.1 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KEY74445.1 - 5.6e-217 721.2 0.6 7.2e-217 720.9 0.6 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEY74445.1 - 3e-102 341.8 0.1 6.4e-102 340.7 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEY74445.1 - 5.1e-56 189.2 1.3 2.6e-54 183.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 KEY74446.1 - 2.1e-35 122.3 30.1 3.1e-35 121.8 30.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.12 KEY74446.1 - 0.65 9.9 4.0 20 5.1 0.1 3.4 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC tRNA-synt_1d PF00750.19 KEY74447.1 - 2.9e-57 194.2 0.1 4.4e-57 193.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEY74447.1 - 1.3e-08 35.1 0.7 1.9e-07 31.3 0.0 2.6 2 1 0 2 2 2 1 DALR anticodon binding domain Clr2_transil PF16761.5 KEY74448.1 - 0.14 13.0 0.0 0.39 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 APH PF01636.23 KEY74450.1 - 5.8e-14 52.6 0.0 1.3e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY74450.1 - 0.028 14.0 0.1 0.059 12.9 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Alk_phosphatase PF00245.20 KEY74451.1 - 1.1e-82 278.2 0.0 1.4e-82 277.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Glyco_hydro_61 PF03443.14 KEY74452.1 - 4.3e-67 226.0 0.0 4.9e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 KEY74454.1 - 1.6e-37 128.9 2.0 3.6e-37 127.7 2.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74454.1 - 5.1e-27 94.9 1.4 9.5e-27 94.1 1.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74454.1 - 1.5e-13 51.0 0.6 2e-13 50.7 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74454.1 - 5.4e-07 29.3 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY74454.1 - 1.3e-05 25.2 0.4 2.1e-05 24.5 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY74454.1 - 4.4e-05 23.2 0.7 6.3e-05 22.6 0.7 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY74454.1 - 0.00017 21.1 0.3 0.00029 20.3 0.3 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY74454.1 - 0.0015 17.8 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEY74454.1 - 0.0049 16.0 0.4 0.0076 15.4 0.4 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 KEY74454.1 - 0.085 13.4 0.2 0.37 11.4 0.2 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Enoyl_reductase PF12241.8 KEY74454.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Sacchrp_dh_NADP PF03435.18 KEY74455.1 - 3e-14 53.4 0.0 6.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEY74455.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEY74456.1 - 1.2e-20 73.8 0.0 8e-18 64.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74456.1 - 3.7e-13 49.6 0.0 1e-12 48.1 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY74458.1 - 1.2e-33 116.2 0.0 1.6e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74458.1 - 3.1e-22 79.3 0.0 4.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74458.1 - 1.9e-06 27.9 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEY74458.1 - 0.00015 21.2 0.0 0.00055 19.4 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEY74458.1 - 0.0079 15.7 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY74458.1 - 0.07 12.5 0.0 3.3 7.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KEY74458.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 KEY74458.1 - 0.087 12.7 0.0 0.61 10.0 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding DUF2256 PF10013.9 KEY74459.1 - 0.038 14.1 4.5 0.28 11.4 4.5 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) CMAS PF02353.20 KEY74460.1 - 1e-57 195.6 0.3 1.2e-57 195.3 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KEY74460.1 - 1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74460.1 - 2.8e-09 37.5 0.0 5.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY74460.1 - 3.1e-08 34.2 0.0 6.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KEY74460.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KEY74460.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KEY74460.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEY74460.1 - 0.0093 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY74460.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KEY74460.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Alk_phosphatase PF00245.20 KEY74461.1 - 1.9e-76 257.7 0.0 2.4e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Acetyltransf_1 PF00583.25 KEY74462.1 - 1.3e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY74462.1 - 3e-09 36.9 0.0 4.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY74462.1 - 6e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY74462.1 - 0.0033 17.5 0.1 0.9 9.6 0.1 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY74462.1 - 0.13 12.2 0.1 0.4 10.7 0.1 1.9 2 1 0 2 2 2 0 FR47-like protein GLEYA PF10528.9 KEY74465.1 - 1.1e-19 70.7 0.1 2.1e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 GLEYA domain AdHead_fibreRBD PF16812.5 KEY74465.1 - 0.014 15.3 1.5 0.023 14.5 0.1 1.9 2 0 0 2 2 2 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Peptidase_S8 PF00082.22 KEY74466.1 - 1.1e-46 159.5 0.4 1.9e-46 158.7 0.4 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEY74466.1 - 9.3e-06 26.3 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Abhydrolase_1 PF00561.20 KEY74467.1 - 8.7e-11 41.9 0.1 3e-10 40.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY74467.1 - 7.5e-06 26.7 0.4 1.1e-05 26.2 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY74467.1 - 0.00027 20.3 0.0 0.0036 16.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KEY74467.1 - 0.00029 20.8 0.1 0.00068 19.6 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) CFEM PF05730.11 KEY74468.1 - 0.0008 19.5 3.3 0.002 18.2 3.3 1.7 1 0 0 1 1 1 1 CFEM domain Aminotran_5 PF00266.19 KEY74469.1 - 6.5e-58 196.4 0.0 8.4e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEY74469.1 - 6.5e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY74469.1 - 0.0002 20.0 0.0 0.0003 19.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 KEY74470.1 - 3.8e-25 88.7 0.0 2.5e-23 82.8 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74470.1 - 9.2e-08 31.7 0.0 0.22 10.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KEY74470.1 - 0.007 16.3 0.1 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY74470.1 - 0.061 12.7 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_Al_protease PF02983.14 KEY74471.1 - 5.6e-13 48.7 0.6 5.6e-13 48.7 0.6 2.1 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KEY74471.1 - 4.4e-08 33.2 10.0 9e-08 32.2 10.0 1.4 1 1 0 1 1 1 1 Trypsin HTH_AsnC-type PF13404.6 KEY74471.1 - 0.07 13.0 1.0 6.3 6.7 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain GMC_oxred_C PF05199.13 KEY74472.1 - 0.00024 21.7 0.1 0.00033 21.2 0.1 1.3 1 1 0 1 1 1 1 GMC oxidoreductase adh_short PF00106.25 KEY74473.1 - 2.4e-21 76.1 0.1 1.7e-19 70.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74473.1 - 4.3e-15 55.9 0.1 2e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74473.1 - 2.6e-10 40.5 0.2 6.5e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74473.1 - 0.017 14.6 0.8 0.044 13.3 0.8 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY74473.1 - 0.034 13.6 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 KEY74473.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.16 KEY74473.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Toprim_2 PF13155.6 KEY74473.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Toprim-like Toprim_3 PF13362.6 KEY74473.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Toprim domain DUF3425 PF11905.8 KEY74474.1 - 1.1e-17 64.2 0.0 2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sulfotransfer_4 PF17784.1 KEY74475.1 - 1.5e-50 172.0 0.0 1.8e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY74475.1 - 0.0016 18.8 0.1 0.0049 17.3 0.0 1.7 1 1 1 2 2 2 1 Sulfotransferase family Kelch_1 PF01344.25 KEY74476.1 - 2.5e-31 107.0 11.5 8.9e-09 34.8 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KEY74476.1 - 6.4e-28 96.1 9.2 9.7e-07 28.9 0.0 6.6 2 1 4 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KEY74476.1 - 1.3e-22 79.6 23.6 4.6e-07 29.7 0.1 6.4 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KEY74476.1 - 1.9e-14 53.5 10.5 0.0018 18.5 0.3 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KEY74476.1 - 6.5e-12 44.9 13.5 0.0012 18.7 0.0 7.0 6 2 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KEY74476.1 - 2.5e-11 43.3 7.4 0.39 10.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif LysM PF01476.20 KEY74479.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 LysM domain Transferase PF02458.15 KEY74481.1 - 7.7e-07 28.1 0.0 4.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Transferase family LysM PF01476.20 KEY74481.1 - 9.3e-05 22.4 0.0 0.037 14.1 0.0 3.7 3 0 0 3 3 3 1 LysM domain AAL_decarboxy PF03306.13 KEY74482.1 - 3.3e-61 206.4 0.0 3.9e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 KEY74483.1 - 1.1e-25 90.2 0.4 2.6e-23 82.5 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEY74483.1 - 2e-24 86.1 0.3 4e-24 85.1 0.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY74483.1 - 2.7e-20 72.5 0.0 7.5e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MAPEG PF01124.18 KEY74485.1 - 1.2e-13 51.1 2.4 1.5e-13 50.8 2.4 1.2 1 0 0 1 1 1 1 MAPEG family LVIVD PF08309.11 KEY74488.1 - 1.5e-07 30.6 0.0 0.08 12.3 0.0 4.0 4 0 0 4 4 4 3 LVIVD repeat Peptidase_S8 PF00082.22 KEY74489.1 - 1.4e-45 155.9 0.2 2.1e-45 155.3 0.2 1.3 1 0 0 1 1 1 1 Subtilase family FlgD_ig PF13860.6 KEY74489.1 - 0.079 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 FlgD Ig-like domain Dimer_Tnp_hAT PF05699.14 KEY74491.1 - 8.4e-21 73.6 0.1 1.8e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_1_7 PF13843.6 KEY74493.1 - 0.053 12.8 0.0 0.055 12.8 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 Zn_clus PF00172.18 KEY74494.1 - 0.003 17.7 5.0 0.0054 16.8 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_Tnp_1_7 PF13843.6 KEY74499.1 - 6.1e-21 75.1 0.0 2e-19 70.1 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 HeLo PF14479.6 KEY74501.1 - 0.11 12.4 2.6 0.4 10.5 1.7 1.9 2 0 0 2 2 2 0 Prion-inhibition and propagation DUF5596 PF18082.1 KEY74502.1 - 0.12 12.2 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Glyco_hydro_64 PF16483.5 KEY74504.1 - 1.7e-113 379.6 0.0 2e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DDE_1 PF03184.19 KEY74505.1 - 8.6e-21 74.4 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HET PF06985.11 KEY74507.1 - 1.1e-06 29.0 0.0 1.8e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spo12 PF05032.12 KEY74508.1 - 0.035 14.0 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Spo12 family Ank_2 PF12796.7 KEY74510.1 - 7.3e-06 26.5 0.1 0.00066 20.2 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74510.1 - 0.00042 20.8 0.2 0.012 16.2 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEY74510.1 - 0.00066 19.9 0.4 0.0023 18.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74510.1 - 0.011 16.2 1.5 0.19 12.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 KEY74510.1 - 0.099 13.1 0.6 1.4 9.5 0.0 3.0 4 1 0 4 4 4 0 Ankyrin repeat Pectate_lyase_3 PF12708.7 KEY74511.1 - 4e-81 272.0 6.3 5.5e-68 229.0 2.0 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEY74511.1 - 0.06 13.0 0.6 0.53 10.0 0.1 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase HET PF06985.11 KEY74512.1 - 5.8e-24 85.1 0.0 2.7e-23 82.9 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.21 KEY74513.1 - 5.4e-64 216.3 26.9 7.2e-64 215.9 26.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3328 PF11807.8 KEY74513.1 - 1.3e-47 162.4 0.1 2.7e-47 161.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Nop14 PF04147.12 KEY74515.1 - 1.6 6.9 22.1 1.9 6.6 22.1 1.2 1 0 0 1 1 1 0 Nop14-like family Flavin_Reduct PF01613.18 KEY74516.1 - 2.4e-20 73.1 0.0 3.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Lipocalin_7 PF14651.6 KEY74516.1 - 0.042 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family E1-E2_ATPase PF00122.20 KEY74517.1 - 4.5e-48 163.2 1.9 4.5e-48 163.2 1.9 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEY74517.1 - 1.8e-22 80.7 1.0 3.6e-22 79.7 1.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEY74517.1 - 3.2e-12 46.7 1.2 1.5e-10 41.4 0.3 2.8 2 0 0 2 2 2 1 Heavy-metal-associated domain EccE PF11203.8 KEY74517.1 - 0.98 9.8 7.2 3.2 8.1 0.5 3.5 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE NCD1 PF04904.13 KEY74518.1 - 0.025 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) DUF4251 PF14059.6 KEY74518.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Isochorismatase PF00857.20 KEY74519.1 - 3.1e-06 27.5 0.0 4.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family UPF0262 PF06793.12 KEY74520.1 - 0.0067 16.5 0.0 0.0084 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) DUF4685 PF15737.5 KEY74520.1 - 0.021 15.3 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) NUDE_C PF04880.13 KEY74521.1 - 0.64 10.5 6.6 1.2 9.5 6.6 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Methyltransf_31 PF13847.6 KEY74522.1 - 4.3e-26 91.5 0.1 4.3e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEY74522.1 - 6.8e-17 62.0 0.7 1.4e-12 48.1 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74522.1 - 8e-16 58.5 0.8 1.5e-13 51.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY74522.1 - 4.2e-14 52.5 0.1 5.5e-13 48.8 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEY74522.1 - 6.1e-06 26.2 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEY74522.1 - 0.00046 20.1 1.8 0.00066 19.6 0.3 1.9 1 1 1 2 2 2 1 Hypothetical methyltransferase PCMT PF01135.19 KEY74522.1 - 0.00067 19.5 0.2 0.002 17.9 0.1 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 KEY74522.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pyr_redox_3 PF13738.6 KEY74523.1 - 3.5e-13 49.5 0.0 1.2e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY74523.1 - 3.8e-12 45.4 0.1 1.6e-11 43.3 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEY74523.1 - 1.2e-10 41.1 0.0 1.7e-09 37.3 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY74523.1 - 9.7e-10 38.1 0.0 1.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY74523.1 - 3.4e-07 30.4 0.0 9.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY74523.1 - 0.00017 21.3 0.0 0.19 11.2 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY74523.1 - 0.00039 20.4 0.0 0.022 14.7 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 KEY74523.1 - 0.13 10.8 0.0 5.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Glyco_hydro_11 PF00457.17 KEY74524.1 - 4.9e-76 254.3 23.4 6.1e-76 254.0 23.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-C2H2_jaz PF12171.8 KEY74525.1 - 1.3e-11 44.5 26.7 0.0039 17.4 1.3 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEY74525.1 - 2e-08 34.3 20.3 7.1e-05 23.1 0.6 7.1 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KEY74525.1 - 6e-08 32.9 30.0 0.039 14.8 0.9 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEY74525.1 - 2.5e-05 24.5 19.6 0.015 15.6 0.4 4.8 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KEY74525.1 - 4.4e-05 23.7 35.6 0.29 11.7 2.3 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type Mucin PF01456.17 KEY74525.1 - 0.025 14.6 4.0 0.06 13.3 4.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF346 PF03984.13 KEY74525.1 - 0.13 12.0 9.3 2.9 7.7 0.5 5.4 5 0 0 5 5 5 0 Repeat of unknown function (DUF346) zf_ZIC PF18366.1 KEY74525.1 - 0.48 10.6 2.5 4.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Zic proteins zinc finger domain MFS_1 PF07690.16 KEY74526.1 - 3e-42 144.8 46.5 3e-42 144.8 46.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY74526.1 - 0.0046 15.9 33.9 0.087 11.7 33.9 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.22 KEY74528.1 - 5.1e-13 48.6 0.2 6.9e-10 38.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.18 KEY74530.1 - 7.9e-10 38.7 7.6 2.4e-09 37.2 7.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY74530.1 - 0.0052 15.8 0.4 0.011 14.7 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY74531.1 - 8.1e-32 110.3 0.2 9.8e-32 110.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74531.1 - 3.4e-23 82.4 0.0 4.4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74531.1 - 6.7e-12 45.7 0.1 9.6e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY74531.1 - 0.00066 18.9 0.0 0.00083 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KEY74531.1 - 0.0089 16.1 0.4 0.044 13.9 0.2 2.0 1 1 2 3 3 3 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KEY74531.1 - 0.03 13.8 0.4 0.12 11.8 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KEY74531.1 - 0.11 12.2 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3871 PF12987.7 KEY74531.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) p450 PF00067.22 KEY74532.1 - 1.8e-47 162.2 0.0 2.3e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 KEY74533.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEY74533.1 - 0.00077 19.1 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Chromo PF00385.24 KEY74534.1 - 6.1e-05 22.8 0.0 0.0067 16.3 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 KEY74535.1 - 2.1e-05 24.0 0.0 4.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SURF6 PF04935.12 KEY74535.1 - 0.00069 19.5 12.5 0.00069 19.5 12.5 1.6 2 0 0 2 2 2 1 Surfeit locus protein 6 APH PF01636.23 KEY74535.1 - 0.0009 19.2 0.0 0.0009 19.2 0.0 2.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2828 PF11443.8 KEY74535.1 - 0.019 13.1 5.5 0.031 12.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pkinase_fungal PF17667.1 KEY74535.1 - 0.02 13.7 0.4 0.52 9.0 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 KEY74535.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rhabdo_ncap PF00945.18 KEY74535.1 - 0.21 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RP-C_C PF11800.8 KEY74535.1 - 0.3 11.2 12.5 0.17 11.9 8.4 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Radial_spoke_3 PF06098.11 KEY74535.1 - 0.36 10.1 17.2 0.68 9.2 17.2 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 DUF913 PF06025.12 KEY74535.1 - 0.75 8.7 4.0 3.1 6.7 4.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 KEY74535.1 - 1.1 7.3 8.2 1.6 6.7 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.19 KEY74535.1 - 1.6 6.6 2.6 2.2 6.1 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TERB2 PF15101.6 KEY74535.1 - 1.8 8.6 8.5 6.2 6.8 7.1 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 NARP1 PF12569.8 KEY74535.1 - 3.7 6.3 10.9 5.8 5.7 10.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Menin PF05053.13 KEY74535.1 - 4 5.7 6.9 6.9 4.9 6.9 1.2 1 0 0 1 1 1 0 Menin DUF4746 PF15928.5 KEY74535.1 - 4.2 6.7 7.4 8.2 5.8 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4770 PF15994.5 KEY74535.1 - 6 7.1 9.2 12 6.1 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ACCA PF03255.14 KEY74535.1 - 8.7 6.2 11.2 20 5.0 11.2 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HET PF06985.11 KEY74536.1 - 2.9e-30 105.5 0.1 4.9e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1174 PF06671.11 KEY74536.1 - 1 9.1 3.4 2.8 7.7 3.4 1.8 1 1 0 1 1 1 0 Repeat of unknown function (DUF1174) SlyX PF04102.12 KEY74538.1 - 0.0011 19.6 2.5 0.0026 18.3 2.5 1.7 1 0 0 1 1 1 1 SlyX Hemerythrin PF01814.23 KEY74538.1 - 0.012 16.3 0.1 0.031 14.9 0.1 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF87 PF01935.17 KEY74538.1 - 0.079 13.0 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4776 PF16003.5 KEY74538.1 - 0.41 9.6 5.5 0.06 12.4 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) PIN_4 PF13638.6 KEY74538.1 - 0.54 10.5 2.5 2.2 8.6 0.1 2.4 2 1 0 2 2 2 0 PIN domain TMF_DNA_bd PF12329.8 KEY74538.1 - 0.98 9.5 6.1 2.2 8.4 6.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APH PF01636.23 KEY74541.1 - 3.3e-11 43.6 0.0 7.4e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY74541.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase HET PF06985.11 KEY74542.1 - 1.3e-31 110.0 1.3 3e-31 108.8 1.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.19 KEY74543.1 - 9.5e-15 54.9 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase KRTAP7 PF15034.6 KEY74544.1 - 0.023 15.6 0.1 0.04 14.9 0.1 1.3 1 0 0 1 1 1 0 KRTAP type 7 family Zn_clus PF00172.18 KEY74545.1 - 0.00013 22.0 7.1 0.00026 21.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY74545.1 - 0.054 12.5 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Epimerase PF01370.21 KEY74546.1 - 5.7e-10 39.1 0.0 0.00051 19.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY74546.1 - 1.7e-06 28.1 0.0 1.1e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEY74546.1 - 0.00048 19.4 0.3 0.0074 15.5 0.1 2.1 1 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KEY74546.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEY74546.1 - 0.009 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEY74546.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY74546.1 - 0.068 12.6 0.0 0.59 9.5 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KEY74546.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 KEY74548.1 - 2.4e-21 76.1 0.0 7.2e-11 42.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74548.1 - 1.9e-16 60.2 0.0 4e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY74548.1 - 8.8e-16 57.6 0.0 0.00055 20.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KEY74548.1 - 3.2e-15 56.0 0.0 2.2e-07 31.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74548.1 - 2.9e-14 51.8 0.0 0.0099 16.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat WD40 PF00400.32 KEY74548.1 - 4.1e-11 43.3 0.8 1.3e-08 35.3 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY74548.1 - 0.00026 21.2 0.1 0.017 15.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain VWA_3_C PF18571.1 KEY74548.1 - 0.011 15.6 1.6 24 4.9 0.0 3.7 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 KEY74548.1 - 0.014 15.3 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Superinfection immunity protein Ge1_WD40 PF16529.5 KEY74548.1 - 0.054 12.5 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 KEY74549.1 - 7.2e-23 81.1 0.0 9.9e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KEY74550.1 - 3e-16 59.4 0.1 5.3e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FixS PF03597.15 KEY74551.1 - 5.8 6.7 7.1 7.4 6.4 1.5 3.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Fungal_trans PF04082.18 KEY74552.1 - 6.8e-09 35.1 1.3 1.1e-08 34.5 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74552.1 - 0.0014 18.7 9.8 0.0014 18.7 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY74553.1 - 2.6e-14 53.2 0.1 2.4e-11 43.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEY74553.1 - 7.6e-08 32.5 0.3 1.1e-07 31.9 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY74553.1 - 3e-05 23.7 0.4 0.0028 17.2 0.4 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ribosomal_L12 PF00542.19 KEY74553.1 - 0.028 14.7 0.2 0.054 13.9 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Methyltransf_2 PF00891.18 KEY74554.1 - 5.2e-17 61.8 0.0 8.7e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KEY74554.1 - 1.4e-06 28.9 0.0 3.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY74554.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KEY74554.1 - 0.0016 19.1 0.0 0.0036 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY74554.1 - 0.0026 17.6 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74554.1 - 0.057 14.1 0.1 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEY74554.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain GidB PF02527.15 KEY74554.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KEY74554.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PS-DH PF14765.6 KEY74555.1 - 6.1e-69 232.5 0.0 1e-68 231.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEY74555.1 - 4.6e-64 216.4 0.0 8.4e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY74555.1 - 8.9e-53 178.9 1.3 8.9e-53 178.9 1.3 2.0 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 KEY74555.1 - 2.4e-50 171.9 0.0 5e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY74555.1 - 2.4e-36 124.3 0.3 5.3e-36 123.2 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEY74555.1 - 7.3e-19 68.4 0.0 4.5e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY74555.1 - 1.3e-10 41.9 0.0 7.9e-10 39.3 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY74555.1 - 2.1e-10 41.0 0.3 2.5e-08 34.3 0.1 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KEY74555.1 - 2.3e-10 41.0 0.0 1.7e-09 38.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KEY74555.1 - 4.5e-10 39.3 3.9 2.6e-09 36.8 0.3 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KEY74555.1 - 3.2e-08 33.6 2.1 1.2e-07 31.8 0.7 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KEY74555.1 - 3.8e-07 30.0 0.0 1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KEY74555.1 - 7.1e-07 29.0 0.2 2.5e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KEY74555.1 - 1.1e-06 29.8 0.1 2.1e-05 25.6 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KEY74555.1 - 2.2e-06 27.6 0.0 6.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEY74555.1 - 4.2e-05 23.0 0.0 9.4e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KEY74555.1 - 4.3e-05 23.8 0.2 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 KEY74555.1 - 0.0003 20.6 0.0 0.00079 19.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_2 PF00891.18 KEY74555.1 - 0.00084 18.7 0.0 0.0058 16.0 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain 3Beta_HSD PF01073.19 KEY74555.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.10 KEY74555.1 - 0.017 14.9 0.5 0.061 13.2 0.5 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KEY74555.1 - 0.019 14.4 0.4 0.038 13.4 0.4 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 KEY74555.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Fungal_trans PF04082.18 KEY74556.1 - 3.7e-05 22.9 0.0 5.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1275 PF06912.11 KEY74557.1 - 1.4e-44 152.3 12.3 1.8e-44 152.0 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4229 PF14012.6 KEY74557.1 - 0.074 13.2 3.4 0.39 10.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF4175 PF13779.6 KEY74557.1 - 0.39 8.6 0.2 0.58 8.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3040 PF11239.8 KEY74557.1 - 1.7 9.0 5.8 0.29 11.4 0.3 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) 2OG-FeII_Oxy PF03171.20 KEY74558.1 - 2.4e-17 63.3 0.0 3.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KEY74558.1 - 3.1e-17 63.4 0.0 4.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 KEY74559.1 - 1.2e-33 116.5 34.5 1.7e-31 109.4 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEY74559.1 - 2.8e-05 23.6 20.6 6.9e-05 22.3 6.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 KEY74559.1 - 0.14 11.8 8.0 0.54 9.9 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Abhydrolase_3 PF07859.13 KEY74560.1 - 1.9e-09 37.7 0.0 2.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY74560.1 - 9.8e-08 31.3 0.2 9.4e-07 28.1 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KEY74560.1 - 0.00086 18.3 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KEY74560.1 - 0.0043 16.0 0.0 0.0056 15.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KEY74560.1 - 0.11 13.0 3.5 0.1 13.2 1.7 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF592 PF04574.13 KEY74560.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) FMN_dh PF01070.18 KEY74561.1 - 2.3e-97 326.1 0.0 2.9e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEY74561.1 - 5.3e-18 64.9 0.0 1.7e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KEY74561.1 - 0.00013 21.1 1.4 0.00036 19.6 0.7 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEY74561.1 - 0.0002 20.6 0.2 0.00031 20.0 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KEY74561.1 - 0.0035 16.8 0.2 0.0054 16.1 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glyoxalase PF00903.25 KEY74562.1 - 2.6e-10 40.6 0.0 3.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAM124 PF15067.6 KEY74562.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 FAM124 family FAD_binding_3 PF01494.19 KEY74563.1 - 8.1e-66 222.6 0.0 1e-65 222.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEY74563.1 - 1.4e-05 24.5 0.2 2.6e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY74563.1 - 5.9e-05 23.2 0.2 0.00054 20.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY74563.1 - 0.00014 21.2 0.0 0.00041 19.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY74563.1 - 0.0016 19.0 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY74563.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KEY74563.1 - 0.013 15.2 0.4 0.065 12.8 1.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Response_reg PF00072.24 KEY74564.1 - 1.1e-17 64.2 0.1 1.8e-17 63.5 0.1 1.3 1 1 0 1 1 1 1 Response regulator receiver domain SGL PF08450.12 KEY74565.1 - 0.0013 18.3 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KEY74565.1 - 0.42 11.2 9.1 16 6.1 0.8 5.7 5 1 0 5 5 5 0 PQQ-like domain Abhydrolase_1 PF00561.20 KEY74567.1 - 1.1e-19 71.1 0.0 2.4e-14 53.6 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KEY74567.1 - 7.6e-19 67.7 0.0 1.8e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Zn_clus PF00172.18 KEY74568.1 - 7.6e-07 29.2 8.5 1.6e-06 28.1 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY74568.1 - 9.3e-07 28.0 0.4 1.3e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KEY74569.1 - 3.2e-15 55.9 0.0 5.7e-08 31.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FSH1 PF03959.13 KEY74570.1 - 1.9e-31 109.4 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KEY74570.1 - 0.0004 21.1 3.1 0.0037 17.9 3.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEY74570.1 - 0.024 14.3 0.1 0.37 10.4 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2119 PF09892.9 KEY74570.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) MFS_1 PF07690.16 KEY74571.1 - 1e-42 146.3 46.2 1e-42 146.3 46.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY74571.1 - 5.1e-09 35.1 25.5 6e-09 34.9 19.2 2.3 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEY74571.1 - 2.1 6.5 9.8 0.29 9.4 1.6 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KEY74572.1 - 5.1e-16 58.5 0.1 1.1e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74572.1 - 3e-10 40.1 12.9 6e-10 39.1 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KEY74573.1 - 1.3e-35 123.2 0.6 1.9e-35 122.7 0.6 1.2 1 0 0 1 1 1 1 Amidase Pro_racemase PF05544.11 KEY74574.1 - 8e-56 189.4 0.0 1.2e-55 188.8 0.0 1.3 1 0 0 1 1 1 1 Proline racemase COesterase PF00135.28 KEY74575.1 - 3.6e-92 309.9 0.0 4.6e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEY74575.1 - 3e-06 27.2 0.1 2.4e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY74575.1 - 0.1 12.1 0.1 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.11 KEY74576.1 - 2.9e-07 30.9 0.0 5.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.21 KEY74577.1 - 1.6e-32 112.7 0.0 6.2e-29 100.9 0.0 3.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KEY74577.1 - 6.5e-19 68.5 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sugar_tr PF00083.24 KEY74578.1 - 5.5e-75 252.9 24.1 6.6e-75 252.7 24.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY74578.1 - 1.6e-25 89.8 31.2 5.8e-22 78.1 22.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5455 PF17537.2 KEY74578.1 - 1.3 9.5 5.7 11 6.5 0.2 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5455) OATP PF03137.20 KEY74578.1 - 7.3 4.8 12.8 11 4.1 0.4 3.3 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 KEY74580.1 - 4e-47 158.7 6.8 9e-14 51.8 0.1 10.1 7 2 3 10 10 10 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY74580.1 - 1.1e-34 114.5 21.5 0.00012 22.2 0.1 16.3 17 1 1 18 18 18 7 Ankyrin repeat Ank_4 PF13637.6 KEY74580.1 - 2.7e-34 117.1 10.1 1.7e-05 25.3 0.0 12.8 11 2 3 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.30 KEY74580.1 - 7.4e-31 105.2 22.1 0.001 19.4 0.1 13.4 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 KEY74580.1 - 3.6e-20 71.8 11.3 0.0013 19.0 0.0 11.9 10 3 3 13 13 13 5 Ankyrin repeats (many copies) Clr5 PF14420.6 KEY74580.1 - 1e-15 57.7 1.8 3.1e-15 56.1 1.8 1.8 1 0 0 1 1 1 1 Clr5 domain DivIC PF04977.15 KEY74581.1 - 0.036 13.8 0.3 0.064 13.0 0.1 1.5 1 1 0 1 1 1 0 Septum formation initiator COMP PF11598.8 KEY74581.1 - 0.17 12.4 0.2 0.25 11.8 0.2 1.2 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Val_tRNA-synt_C PF10458.9 KEY74581.1 - 0.19 12.0 5.1 0.23 11.8 5.1 1.1 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Ysc84 PF04366.12 KEY74582.1 - 2.1e-48 163.3 0.0 3.9e-48 162.4 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Fringe PF02434.16 KEY74583.1 - 3.6e-07 29.9 0.0 7.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KEY74583.1 - 2e-05 24.1 0.0 7.9e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF604 BRO1 PF03097.18 KEY74584.1 - 2.1e-122 408.7 0.0 3.3e-122 408.1 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KEY74584.1 - 3.9e-80 269.3 2.5 3.9e-80 269.3 2.5 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV K-box PF01486.17 KEY74584.1 - 0.12 12.6 3.2 0.19 11.9 0.0 2.8 3 0 0 3 3 3 0 K-box region Band_7 PF01145.25 KEY74585.1 - 1.3e-14 54.6 0.1 1.3e-14 54.6 0.1 3.5 2 2 0 2 2 2 1 SPFH domain / Band 7 family Amidohydro_1 PF01979.20 KEY74585.1 - 0.25 10.6 3.2 0.41 9.9 3.2 1.4 1 0 0 1 1 1 0 Amidohydrolase family LCIB_C_CA PF18599.1 KEY74585.1 - 0.49 9.6 4.9 0.88 8.8 4.9 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases His_Phos_2 PF00328.22 KEY74586.1 - 0.00057 19.4 0.1 0.085 12.2 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 KEY74586.1 - 0.039 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PDGLE domain Phage_Coat_B PF05356.11 KEY74586.1 - 0.041 13.8 0.7 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 Phage Coat protein B 2-Hacid_dh_C PF02826.19 KEY74587.1 - 1.2e-43 148.5 0.0 2.3e-43 147.6 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY74587.1 - 1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AAA PF00004.29 KEY74588.1 - 1.9e-17 63.9 0.0 3.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEY74588.1 - 0.00029 21.1 0.2 0.021 15.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KEY74588.1 - 0.00092 19.6 0.4 0.005 17.2 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain Zot PF05707.12 KEY74588.1 - 0.0095 15.6 0.0 0.15 11.7 0.0 2.3 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 KEY74588.1 - 0.018 15.2 0.1 0.099 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEY74588.1 - 0.13 12.8 0.2 0.71 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KEY74588.1 - 0.2 10.6 0.6 0.36 9.8 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HSP20 PF00011.21 KEY74589.1 - 2e-17 63.2 0.2 1.1e-11 44.8 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEY74589.1 - 0.00042 19.8 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Cutinase PF01083.22 KEY74590.1 - 1.4e-45 155.5 0.0 1.6e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KEY74590.1 - 0.00022 21.2 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KEY74590.1 - 0.00032 20.3 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_transf_28 PF03033.20 KEY74590.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Abhydrolase_2 PF02230.16 KEY74590.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3854 PF12965.7 KEY74591.1 - 0.044 13.8 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Stanniocalcin PF03298.13 KEY74591.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Stanniocalcin family NMO PF03060.15 KEY74592.1 - 2.8e-32 112.4 15.4 4.1e-27 95.4 8.2 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KEY74592.1 - 3.1e-12 46.2 1.1 1e-11 44.5 1.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEY74592.1 - 6.6e-09 35.2 1.7 9.9e-09 34.7 1.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEY74592.1 - 0.001 18.3 0.2 0.0017 17.6 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase CorA PF01544.18 KEY74593.1 - 3.7e-13 49.4 0.1 6.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 KEY74593.1 - 0.026 15.1 0.9 1.2 9.7 0.1 2.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YojJ PF10372.9 KEY74593.1 - 0.051 13.7 0.4 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Takusan PF04822.13 KEY74593.1 - 0.052 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Takusan ADH_N PF08240.12 KEY74594.1 - 6.2e-05 22.8 0.1 0.0002 21.2 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 KEY74596.1 - 3.9e-53 180.8 0.0 4.9e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mre11_DNA_bind PF04152.14 KEY74597.1 - 3.4e-52 177.2 0.3 3.4e-52 177.2 0.3 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KEY74597.1 - 1.3e-15 58.5 1.3 1.7e-15 58.1 0.7 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY74597.1 - 3.2e-05 24.2 0.0 0.00033 20.9 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 KEY74598.1 - 3.1e-19 69.1 26.1 1.3e-16 60.5 17.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEY74598.1 - 4.3e-07 29.7 5.4 4.3e-07 29.7 5.4 2.4 2 1 0 2 2 2 1 Nodulin-like Claudin_3 PF06653.11 KEY74598.1 - 0.062 13.2 0.4 0.062 13.2 0.4 2.7 4 1 0 4 4 4 0 Tight junction protein, Claudin-like DUF4516 PF14990.6 KEY74598.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Epimerase PF01370.21 KEY74600.1 - 1.2e-21 77.3 0.0 2.5e-21 76.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEY74600.1 - 7e-19 68.4 0.1 4.1e-13 49.4 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEY74600.1 - 1.4e-10 40.8 0.1 9.9e-08 31.4 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEY74600.1 - 2.6e-09 36.6 0.0 3.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEY74600.1 - 7.9e-08 31.8 0.2 1.4e-06 27.7 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein Inositol_P PF00459.25 KEY74601.1 - 8.5e-34 117.3 0.0 1.6e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2733 PF10813.8 KEY74601.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Rep-A_N PF04057.12 KEY74602.1 - 0.051 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain BRCA-2_OB1 PF09103.10 KEY74602.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TALPID3 PF15324.6 KEY74602.1 - 4.4 4.8 24.5 0.055 11.1 17.3 1.3 2 0 0 2 2 2 0 Hedgehog signalling target GMC_oxred_N PF00732.19 KEY74603.1 - 2.5e-64 217.5 0.0 3.5e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY74603.1 - 1.9e-31 109.5 0.0 3.3e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lipocalin_2 PF08212.12 KEY74603.1 - 9.8e-19 67.7 0.0 1.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Lycopene_cycl PF05834.12 KEY74603.1 - 0.028 13.5 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GST_N PF02798.20 KEY74604.1 - 5.4e-14 52.3 0.0 9.3e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY74604.1 - 5.4e-08 33.0 0.0 8.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEY74604.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FAD_binding_4 PF01565.23 KEY74606.1 - 3.9e-22 78.5 4.5 2.4e-21 75.9 4.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEY74606.1 - 4.3e-08 33.1 0.1 8.4e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box PF00646.33 KEY74607.1 - 0.00062 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEY74607.1 - 0.027 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like CDC45 PF02724.14 KEY74607.1 - 0.047 12.0 0.9 0.066 11.5 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Eapp_C PF10238.9 KEY74607.1 - 0.069 13.2 2.8 0.13 12.3 2.8 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein N6_N4_Mtase PF01555.18 KEY74607.1 - 0.094 12.4 0.9 0.2 11.3 0.9 1.5 1 0 0 1 1 1 0 DNA methylase AIM3 PF17096.5 KEY74607.1 - 0.26 12.3 2.4 0.56 11.2 2.4 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 FAM176 PF14851.6 KEY74607.1 - 1.1 8.9 4.4 1.9 8.1 4.4 1.3 1 0 0 1 1 1 0 FAM176 family SnoaL PF07366.12 KEY74608.1 - 4.6e-24 84.6 0.0 5.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEY74608.1 - 6e-12 46.1 0.0 8.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DDE_Tnp_1_7 PF13843.6 KEY74609.1 - 9.9e-34 117.2 0.0 4e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 Transposase IS4 TMEM40 PF15817.5 KEY74610.1 - 0.13 12.0 0.1 0.61 9.9 0.1 2.1 1 0 0 1 1 1 0 Transmembrane protein 40 family Zn_clus PF00172.18 KEY74611.1 - 0.46 10.6 14.3 0.85 9.8 14.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY74612.1 - 5.5e-13 48.8 0.0 8.5e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74612.1 - 1e-07 31.8 0.0 2.4e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CBM-like PF14683.6 KEY74613.1 - 6.1e-34 117.3 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KEY74613.1 - 2.3e-11 43.3 0.2 7.4e-11 41.7 0.2 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KEY74613.1 - 3e-09 37.0 0.8 2.1e-07 31.1 0.3 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain EF-hand_6 PF13405.6 KEY74613.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF2012 PF09430.10 KEY74613.1 - 0.052 13.7 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) EF-hand_1 PF00036.32 KEY74613.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 EF hand Semialdhyde_dh PF01118.24 KEY74614.1 - 3.4e-23 82.4 0.1 7.3e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY74614.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KEY74616.1 - 3.1e-20 72.3 0.8 5e-20 71.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY74616.1 - 2e-10 40.6 0.3 4.1e-10 39.6 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box PF00646.33 KEY74617.1 - 0.00019 21.2 1.6 0.0008 19.2 1.6 2.1 1 0 0 1 1 1 1 F-box domain IL34 PF15036.6 KEY74617.1 - 0.00039 20.5 0.0 0.0007 19.7 0.0 1.3 1 0 0 1 1 1 1 Interleukin 34 F-box-like PF12937.7 KEY74617.1 - 0.0013 18.6 0.6 0.0033 17.3 0.6 1.7 1 0 0 1 1 1 1 F-box-like Beta_helix PF13229.6 KEY74617.1 - 0.006 16.4 0.1 0.0086 15.9 0.1 1.2 1 0 0 1 1 1 1 Right handed beta helix region HATPase_c PF02518.26 KEY74618.1 - 1.2e-21 77.4 0.0 3.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEY74618.1 - 4.3e-19 68.7 0.0 9.7e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEY74618.1 - 1.2e-12 47.7 0.0 4.1e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KEY74618.1 - 5.4e-08 33.5 0.0 2.1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 GAF domain ABC2_membrane PF01061.24 KEY74619.1 - 5.2e-76 254.7 63.6 3.8e-39 134.3 17.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEY74619.1 - 4.4e-37 127.6 0.0 2.2e-19 70.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY74619.1 - 2e-27 94.9 12.1 3.8e-24 84.4 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY74619.1 - 2.1e-12 47.5 3.4 1.1e-11 45.2 3.4 2.2 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEY74619.1 - 8.9e-08 31.6 38.6 5.5e-07 29.0 9.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KEY74619.1 - 1.2e-05 25.0 0.2 0.0072 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY74619.1 - 1.5e-05 25.0 0.1 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KEY74619.1 - 2.8e-05 24.3 0.9 0.0086 16.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEY74619.1 - 9.4e-05 22.9 1.7 0.013 15.9 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KEY74619.1 - 0.00048 19.8 1.1 0.055 13.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KEY74619.1 - 0.00051 20.6 0.1 0.0029 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEY74619.1 - 0.0015 18.0 0.0 0.005 16.3 0.0 1.8 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEY74619.1 - 0.0055 16.8 0.1 5.4 7.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEY74619.1 - 0.021 15.2 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KEY74619.1 - 0.022 15.1 2.0 1.4 9.2 0.2 3.2 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KEY74619.1 - 0.023 14.3 2.4 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KEY74619.1 - 0.025 14.4 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KEY74619.1 - 0.032 14.2 1.0 5.5 6.9 0.2 2.8 2 0 0 2 2 2 0 NACHT domain dNK PF01712.19 KEY74619.1 - 0.037 13.9 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 KEY74619.1 - 0.05 13.5 0.6 0.43 10.5 0.0 2.4 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KEY74619.1 - 0.064 13.0 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEY74619.1 - 0.12 12.1 2.6 3.3 7.4 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEY74619.1 - 0.65 10.4 2.5 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain CN_hydrolase PF00795.22 KEY74620.1 - 1.5e-32 112.9 0.0 1e-31 110.3 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase WLM PF08325.10 KEY74621.1 - 2.1e-51 174.7 0.3 9.1e-51 172.7 0.0 1.9 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 KEY74621.1 - 0.00047 19.9 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF45 PF01863.17 KEY74621.1 - 0.0015 18.6 0.7 0.0034 17.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KEY74621.1 - 0.004 17.0 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 SprT-like family TBK1_ULD PF18396.1 KEY74621.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Reprolysin_5 PF13688.6 KEY74621.1 - 0.044 13.9 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Ubiquitin_2 PF14560.6 KEY74621.1 - 0.12 12.8 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain ER_lumen_recept PF00810.18 KEY74622.1 - 7e-54 182.7 3.8 7e-54 182.7 3.8 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor TFIID_30kDa PF03540.13 KEY74623.1 - 4.1e-26 90.7 0.4 6.5e-26 90.0 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KEY74623.1 - 0.018 15.6 1.6 0.032 14.8 1.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TAF4 PF05236.14 KEY74623.1 - 0.092 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_S19 PF00203.21 KEY74624.1 - 9.4e-28 95.9 0.0 1.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 HET PF06985.11 KEY74625.1 - 2.7e-29 102.4 0.2 5.2e-29 101.5 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2491 PF10679.9 KEY74625.1 - 0.041 13.1 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) TGT_C1 PF14809.6 KEY74625.1 - 0.14 12.4 0.0 0.44 10.9 0.0 1.7 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation Peptidase_C48 PF02902.19 KEY74626.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FMN_dh PF01070.18 KEY74627.1 - 3.9e-122 407.6 0.4 3.9e-122 407.6 0.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Sulfatase PF00884.23 KEY74627.1 - 3.2e-57 194.3 0.1 4.4e-57 193.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase IMPDH PF00478.25 KEY74627.1 - 9.7e-10 38.0 0.3 2.3e-09 36.7 0.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEY74627.1 - 4.3e-07 29.4 1.8 3.5e-06 26.4 1.7 2.1 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KEY74627.1 - 4.4e-07 29.6 0.7 7.4e-07 28.9 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KEY74627.1 - 1.8e-05 24.1 0.5 0.00052 19.3 0.0 2.2 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KEY74627.1 - 7.6e-05 22.1 9.7 0.0055 16.0 0.2 3.9 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEY74627.1 - 0.00093 18.7 0.4 0.0077 15.7 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KEY74627.1 - 0.0043 16.5 0.2 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KEY74627.1 - 0.0094 15.1 0.1 0.13 11.3 0.1 2.3 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Phosphodiest PF01663.22 KEY74627.1 - 0.038 13.6 0.1 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase PcrB PF01884.17 KEY74627.1 - 0.35 10.3 1.1 2.9 7.3 0.2 2.2 1 1 1 2 2 2 0 PcrB family Peptidase_M61 PF05299.12 KEY74628.1 - 3.3e-05 24.2 3.4 0.0033 17.8 3.4 2.4 1 1 0 1 1 1 1 M61 glycyl aminopeptidase DUF2268 PF10026.9 KEY74628.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Peptidase_M1 PF01433.20 KEY74628.1 - 0.0077 15.8 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Toxin_ToxA PF11584.8 KEY74631.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA E1-E2_ATPase PF00122.20 KEY74632.1 - 2e-26 92.6 0.4 2.3e-26 92.4 0.4 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Big_6 PF17936.1 KEY74632.1 - 0.00086 19.5 0.2 0.002 18.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial Ig domain EKR PF10371.9 KEY74632.1 - 0.026 14.3 0.3 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function MFS_1 PF07690.16 KEY74633.1 - 4.9e-09 35.6 1.8 6.4e-09 35.2 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.6 KEY74633.1 - 0.02 14.6 0.4 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Neurensin 4HBT PF03061.22 KEY74634.1 - 4.7e-05 23.7 0.1 0.0001 22.6 0.1 1.6 1 1 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KEY74634.1 - 0.0017 18.5 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4442) Beta-lactamase PF00144.24 KEY74635.1 - 6.9e-41 140.6 0.2 8.4e-41 140.3 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KEY74635.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family Cellulase PF00150.18 KEY74636.1 - 6.9e-52 176.6 1.4 8.2e-52 176.4 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KEY74636.1 - 0.012 15.2 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DUF1977 PF09320.11 KEY74637.1 - 3.2e-28 98.0 0.1 8.4e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KEY74637.1 - 1.7e-19 69.7 0.0 3.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain MINDY_DUB PF04424.13 KEY74638.1 - 4.7e-25 87.9 0.0 7.3e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase 4HBT PF03061.22 KEY74638.1 - 0.21 12.0 0.7 1.8 9.0 0.1 2.5 3 0 0 3 3 3 0 Thioesterase superfamily Pec_lyase_C PF00544.19 KEY74639.1 - 2.3e-42 145.0 1.0 3.5e-42 144.4 1.0 1.2 1 0 0 1 1 1 1 Pectate lyase NICE-1 PF15845.5 KEY74639.1 - 6.5 7.6 14.9 5.8 7.8 13.0 1.9 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family Steroid_dh PF02544.16 KEY74640.1 - 5.4e-24 84.9 0.6 2.9e-23 82.5 0.6 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEY74640.1 - 0.0015 18.1 1.9 0.0032 17.0 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Epimerase PF01370.21 KEY74641.1 - 3.9e-13 49.4 0.1 1.3e-12 47.7 0.1 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY74641.1 - 5.6e-11 42.7 0.0 1.6e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEY74641.1 - 5e-08 32.7 0.0 9.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY74641.1 - 1.6e-07 30.7 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEY74641.1 - 8.7e-05 22.2 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KEY74641.1 - 0.00096 18.4 0.0 0.007 15.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KEY74641.1 - 0.0022 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KEY74641.1 - 0.0042 16.6 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KEY74641.1 - 0.0075 15.4 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KEY74641.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC2_membrane PF01061.24 KEY74642.1 - 3.9e-58 196.3 45.7 5.5e-31 107.6 16.4 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEY74642.1 - 8.8e-42 142.9 0.0 1.5e-20 74.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEY74642.1 - 6.6e-25 86.8 2.1 1.9e-19 69.3 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter AAA_22 PF13401.6 KEY74642.1 - 9.1e-07 29.2 0.1 0.11 12.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEY74642.1 - 2.1e-06 28.3 0.3 0.0041 17.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEY74642.1 - 6.3e-06 26.2 0.0 0.11 12.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEY74642.1 - 1.3e-05 25.8 0.0 0.034 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEY74642.1 - 1.9e-05 24.7 0.4 9.4e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KEY74642.1 - 0.00019 21.2 1.4 0.71 9.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEY74642.1 - 0.00024 21.3 0.0 0.62 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEY74642.1 - 0.00037 20.2 3.3 0.027 14.2 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KEY74642.1 - 0.00046 20.5 0.0 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY74642.1 - 0.00085 19.3 0.2 0.92 9.4 0.3 2.5 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 KEY74642.1 - 0.0015 17.9 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KEY74642.1 - 0.002 17.7 0.8 0.047 13.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEY74642.1 - 0.0049 17.0 0.2 0.16 12.1 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KEY74642.1 - 0.0089 16.5 0.0 4.1 7.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_trans_N PF14510.6 KEY74642.1 - 0.011 16.3 0.5 0.038 14.6 0.0 2.2 2 0 0 2 2 1 0 ABC-transporter N-terminal Pox_A32 PF04665.12 KEY74642.1 - 0.02 14.3 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.22 KEY74642.1 - 0.021 14.0 0.4 0.53 9.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KEY74642.1 - 0.022 15.3 0.1 0.046 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEY74642.1 - 0.028 14.0 0.7 1.4 8.5 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEY74642.1 - 0.031 14.0 0.4 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KEY74642.1 - 0.032 14.2 0.9 0.91 9.5 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KEY74642.1 - 0.033 14.5 0.0 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KEY74642.1 - 0.033 13.0 0.3 0.22 10.2 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 KEY74642.1 - 0.034 13.9 0.3 6.5 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 KEY74642.1 - 0.036 13.1 0.4 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KEY74642.1 - 0.038 13.3 1.0 1.5 8.1 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KEY74642.1 - 0.041 13.8 0.2 12 5.8 0.0 3.1 3 0 0 3 3 3 0 NTPase SMC_N PF02463.19 KEY74642.1 - 0.072 12.5 0.0 19 4.6 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Septin PF00735.18 KEY74642.1 - 0.11 11.8 0.1 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_17 PF13207.6 KEY74642.1 - 0.11 12.9 0.1 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEY74642.1 - 0.19 12.1 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 KEY74642.1 - 0.24 10.9 0.4 5.8 6.4 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KEY74642.1 - 0.32 10.8 0.6 15 5.3 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KEY74642.1 - 0.76 9.4 1.8 11 5.5 0.5 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fungal_trans PF04082.18 KEY74643.1 - 4.2e-15 55.5 0.7 5.8e-15 55.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74643.1 - 1.6e-05 24.9 11.1 1.6e-05 24.9 11.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_M PF01031.20 KEY74644.1 - 2.7e-06 26.8 0.1 1.4e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KEY74644.1 - 0.013 15.6 0.4 0.056 13.6 0.4 2.1 1 1 0 1 1 1 0 Dynamin GTPase effector domain Pirin PF02678.16 KEY74645.1 - 2.4e-30 104.7 0.6 3.1e-29 101.1 0.3 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KEY74645.1 - 1.6e-21 76.6 0.0 1.7e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KEY74645.1 - 2.5e-07 30.3 1.2 9.3e-05 22.1 0.5 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KEY74645.1 - 0.0002 21.0 0.4 0.58 9.9 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF861) Peptidase_M19 PF01244.21 KEY74646.1 - 2.6e-101 339.0 0.1 3e-101 338.8 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) CN_hydrolase PF00795.22 KEY74647.1 - 9.5e-43 146.4 0.0 1.3e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 2-Hacid_dh_C PF02826.19 KEY74648.1 - 1.3e-39 135.4 0.0 2.8e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KEY74648.1 - 2.7e-32 112.7 0.6 5.6e-32 111.7 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh PF00389.30 KEY74648.1 - 4e-15 55.7 0.0 9.2e-15 54.5 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sacchrp_dh_NADP PF03435.18 KEY74648.1 - 0.0017 18.6 0.1 0.82 9.9 0.0 2.9 2 1 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 KEY74648.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 KEY74648.1 - 0.058 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEY74648.1 - 0.12 12.9 0.0 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 KEY74648.1 - 5.5 7.3 5.1 0.96 9.7 0.3 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 KEY74649.1 - 1.1e-25 90.2 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KEY74650.1 - 2.9e-62 211.0 0.0 3.3e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ComX PF05952.12 KEY74650.1 - 0.13 12.2 0.0 0.96 9.4 0.0 2.3 3 0 0 3 3 3 0 Bacillus competence pheromone ComX Peptidase_M20 PF01546.28 KEY74651.1 - 1.6e-24 86.8 0.1 5.8e-24 84.9 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY74651.1 - 1.3e-15 57.2 0.0 2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEY74651.1 - 5.9e-06 26.1 0.0 8.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.16 KEY74652.1 - 1.8e-40 139.0 41.0 8.6e-36 123.6 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 KEY74652.1 - 0.00098 19.4 10.9 0.017 15.4 0.1 3.6 2 1 0 3 3 3 2 Domain of unknown function (DUF1772) Hydantoinase_B PF02538.14 KEY74653.1 - 1e-206 687.4 0.1 1.3e-206 687.0 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEY74653.1 - 1.1e-91 307.2 0.1 2.6e-91 305.9 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEY74653.1 - 2.1e-58 197.0 0.4 4.6e-57 192.6 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Helo_like_N PF17111.5 KEY74654.1 - 0.052 12.9 3.3 0.058 12.8 0.0 2.5 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Baculo_p24 PF05073.12 KEY74654.1 - 0.12 12.2 1.3 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Baculovirus P24 capsid protein bZIP_1 PF00170.21 KEY74655.1 - 0.00046 20.2 3.1 0.0011 19.0 3.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY74655.1 - 0.00093 19.2 5.8 0.0023 18.0 5.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 KEY74655.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Sina PF03145.16 KEY74655.1 - 0.14 12.1 4.5 3.3 7.6 1.0 2.5 2 0 0 2 2 2 0 Seven in absentia protein family zf-H2C2_2 PF13465.6 KEY74655.1 - 7.7 7.1 8.1 4.3 7.9 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger double domain MFS_1 PF07690.16 KEY74656.1 - 3.6e-20 72.2 56.1 5.6e-19 68.3 52.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEY74656.1 - 4.4e-05 22.1 26.1 6.2e-05 21.6 26.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KEY74657.1 - 0.00067 19.5 0.9 0.0041 17.0 0.9 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KEY74657.1 - 0.012 15.5 1.5 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 KEY74658.1 - 4.2e-10 40.1 0.0 6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY74658.1 - 6.3e-07 29.2 0.1 0.038 14.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KEY74658.1 - 2.6e-06 27.9 0.1 0.077 13.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY74658.1 - 6.6e-05 23.2 0.9 0.18 12.3 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KEY74658.1 - 0.021 15.2 3.2 0.26 11.6 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Glyco_hydro_32N PF00251.20 KEY74659.1 - 1.3e-158 527.4 6.4 5.4e-71 239.6 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY74659.1 - 6.8e-59 198.4 0.5 4e-32 111.4 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KEY74659.1 - 0.0029 17.3 4.5 1.9 8.8 0.1 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KEY74659.1 - 0.01 14.7 0.0 0.65 8.7 0.0 2.3 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KEY74659.1 - 0.027 14.4 0.1 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain GH101_N PF17995.1 KEY74659.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal BNR_2 PF13088.6 KEY74659.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.5 2 1 0 2 2 2 0 BNR repeat-like domain FA_desaturase_2 PF03405.14 KEY74660.1 - 0.068 12.0 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF3253 PF11625.8 KEY74661.1 - 0.13 12.5 0.0 3.4 8.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3253) AAA PF00004.29 KEY74662.1 - 7.6e-19 68.4 0.0 4.9e-18 65.8 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEY74662.1 - 0.0012 19.3 0.1 0.0048 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY74662.1 - 0.0013 19.0 1.6 0.0021 18.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEY74662.1 - 0.005 17.0 0.1 0.057 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEY74662.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEY74662.1 - 0.0056 17.2 2.0 0.097 13.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KEY74662.1 - 0.067 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KEY74662.1 - 0.068 12.7 0.2 0.68 9.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KEY74662.1 - 0.088 12.8 1.6 1.2 9.2 0.2 2.8 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KEY74662.1 - 0.12 12.8 0.1 0.38 11.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEY74662.1 - 0.19 11.0 1.6 1.3 8.2 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.6 KEY74662.1 - 2.5 8.3 9.5 0.64 10.2 1.1 3.8 3 1 1 4 4 4 0 AAA domain Bac_rhamnosid6H PF17389.2 KEY74665.1 - 3.6e-108 361.8 0.1 4.9e-108 361.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KEY74665.1 - 1.3e-54 184.6 0.1 3.6e-54 183.2 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KEY74665.1 - 1.6e-30 105.0 0.0 3.2e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KEY74665.1 - 1.5e-23 82.4 0.3 9.9e-23 79.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Late_protein_L2 PF00513.18 KEY74667.1 - 0.29 10.1 4.6 0.36 9.8 4.6 1.1 1 0 0 1 1 1 0 Late Protein L2 CCDC106 PF15794.5 KEY74669.1 - 0.0035 17.1 0.7 0.0035 17.1 0.7 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 DUF4763 PF15960.5 KEY74669.1 - 0.011 15.1 1.1 0.011 15.1 1.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Lipoprotein_20 PF13942.6 KEY74669.1 - 0.036 14.0 3.0 0.062 13.2 3.0 1.4 1 0 0 1 1 1 0 YfhG lipoprotein adh_short_C2 PF13561.6 KEY74670.1 - 2.4e-44 151.7 1.8 5.6e-38 130.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY74670.1 - 1.2e-41 142.3 0.5 1.6e-41 141.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY74670.1 - 5.8e-15 55.7 0.3 7.5e-15 55.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74670.1 - 0.00047 19.7 0.3 0.0031 17.0 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dabb PF07876.12 KEY74671.1 - 2.9e-21 75.9 0.0 3.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RPE65 PF03055.15 KEY74672.1 - 3.4e-96 323.2 0.0 4.1e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cation_efflux PF01545.21 KEY74673.1 - 6.7e-31 107.6 4.2 7.7e-31 107.4 4.2 1.0 1 0 0 1 1 1 1 Cation efflux family DUF3425 PF11905.8 KEY74674.1 - 1.2e-18 67.3 0.1 2.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Transp_cyt_pur PF02133.15 KEY74675.1 - 2.1e-31 109.2 32.4 1.7e-30 106.2 32.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin His_Phos_1 PF00300.22 KEY74676.1 - 0.039 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) FMN_dh PF01070.18 KEY74677.1 - 3.2e-82 276.4 0.0 3.2e-50 171.1 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 KEY74677.1 - 4.5e-05 23.0 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KEY74677.1 - 7.9e-05 22.1 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KEY74677.1 - 0.00015 20.9 0.1 0.00065 18.8 0.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KEY74677.1 - 0.012 14.9 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KEY74677.1 - 0.024 14.1 0.1 5.5 6.4 0.0 2.8 1 1 2 3 3 3 0 Histidine biosynthesis protein Glu_synthase PF01645.17 KEY74677.1 - 0.04 13.1 0.0 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 Conserved region in glutamate synthase Peptidase_M19 PF01244.21 KEY74677.1 - 0.14 11.3 0.0 0.36 9.9 0.0 1.6 2 1 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DUF572 PF04502.13 KEY74678.1 - 1.2e-55 189.4 0.6 1.4e-55 189.3 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zinc-ribbons_6 PF07191.12 KEY74678.1 - 0.38 10.8 2.2 1.1 9.3 0.8 2.5 3 1 0 3 3 3 0 zinc-ribbons Glyco_hydro_43 PF04616.14 KEY74679.1 - 2.7e-30 105.7 7.6 3.7e-30 105.2 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY74679.1 - 4.3e-25 88.6 0.0 5.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain APH PF01636.23 KEY74680.1 - 5.7e-11 42.8 0.3 9.6e-11 42.1 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEY74680.1 - 0.00088 18.7 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEY74680.1 - 0.0021 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KEY74680.1 - 0.022 14.1 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Helicase_C_2 PF13307.6 KEY74681.1 - 6e-58 195.8 0.0 1.3e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEY74681.1 - 3.1e-47 160.5 0.0 4.8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L27A PF00828.19 KEY74683.1 - 1.9e-08 35.0 0.0 1.9e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KEY74684.1 - 1.6e-42 145.7 0.0 8.1e-39 133.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74684.1 - 1.2e-14 54.2 0.0 6.8e-09 35.4 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KEY74684.1 - 3e-05 24.1 0.5 0.013 15.4 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KEY74684.1 - 0.013 15.2 0.0 0.085 12.5 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KEY74684.1 - 0.013 14.8 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KEY74684.1 - 0.016 14.0 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEY74684.1 - 0.018 14.4 0.1 0.4 10.0 0.1 2.5 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1_N PF12922.7 KEY74685.1 - 1.4e-64 216.9 0.2 1.9e-63 213.2 0.1 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KEY74685.1 - 2e-49 167.7 4.2 1.2e-44 152.2 0.1 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEY74685.1 - 1.8e-11 43.2 1.4 0.024 14.9 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KEY74685.1 - 1e-09 38.6 3.2 9.2e-05 22.8 0.1 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KEY74685.1 - 5.9e-06 26.7 5.7 0.032 14.7 0.2 5.1 4 0 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 KEY74685.1 - 1.4e-05 25.2 0.1 0.026 14.7 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KEY74685.1 - 0.00011 21.0 3.9 0.029 12.9 0.1 3.7 3 2 1 4 4 4 2 Adaptin N terminal region Cnd3 PF12719.7 KEY74685.1 - 0.00073 18.8 6.3 0.0013 18.0 0.3 3.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain ACBP PF00887.19 KEY74685.1 - 0.029 14.6 0.2 0.11 12.7 0.2 2.0 1 0 0 1 1 1 0 Acyl CoA binding protein Ald_Xan_dh_C2 PF02738.18 KEY74685.1 - 0.04 12.4 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase MIEAP PF16026.5 KEY74685.1 - 0.069 13.4 0.1 0.28 11.4 0.1 2.1 1 0 0 1 1 1 0 Mitochondria-eating protein NIF PF03031.18 KEY74686.1 - 5e-27 94.6 2.0 6.4e-27 94.2 0.0 2.2 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KEY74686.1 - 1.2e-06 28.8 0.0 3.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KEY74686.1 - 1.4e-05 24.9 0.2 5.1e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT_3 PF18428.1 KEY74686.1 - 0.0069 16.4 1.2 0.018 15.1 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KEY74686.1 - 0.035 14.0 0.1 0.098 12.5 0.0 1.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KEY74686.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KEY74686.1 - 0.082 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain IATP PF04568.12 KEY74686.1 - 0.18 12.2 0.1 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP CDC45 PF02724.14 KEY74686.1 - 5.5 5.1 11.8 3.2 6.0 5.0 2.1 2 0 0 2 2 2 0 CDC45-like protein adh_short PF00106.25 KEY74687.1 - 1e-19 70.8 0.0 1.2e-15 57.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74687.1 - 3.1e-09 36.7 0.0 3.2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74687.1 - 3.4e-07 30.3 0.1 6.7e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 KR domain HEAT PF02985.22 KEY74687.1 - 0.076 13.3 0.1 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Polysacc_synt_2 PF02719.15 KEY74687.1 - 0.081 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GRIM-19 PF06212.12 KEY74688.1 - 3.7e-20 72.2 1.3 7.2e-19 68.1 1.3 2.4 1 1 0 1 1 1 1 GRIM-19 protein MFS_1 PF07690.16 KEY74690.1 - 8.8e-26 90.6 50.6 1e-24 87.2 36.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY74690.1 - 0.00069 18.6 31.4 0.013 14.4 13.2 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter DUF4246 PF14033.6 KEY74692.1 - 1.4e-10 40.9 0.1 1.8e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HET PF06985.11 KEY74693.1 - 8.8e-15 55.3 0.0 4.4e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Melibiase_2_C PF17450.2 KEY74695.1 - 0.058 13.6 0.0 10 6.4 0.0 2.2 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain HET PF06985.11 KEY74696.1 - 2.4e-34 118.8 0.1 5.5e-34 117.6 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.21 KEY74697.1 - 1.7e-39 134.6 0.0 1.8e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_3 PF07859.13 KEY74698.1 - 8e-62 208.8 0.1 1e-61 208.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEY74698.1 - 0.00052 19.0 0.1 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEY74698.1 - 0.0093 15.5 0.1 0.039 13.4 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KEY74698.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF3311 PF11755.8 KEY74698.1 - 0.099 12.6 0.1 0.099 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) SGL PF08450.12 KEY74699.1 - 9.6e-60 202.2 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF839 PF05787.13 KEY74699.1 - 0.0049 16.1 0.2 0.079 12.1 0.0 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF839) Arylesterase PF01731.20 KEY74699.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Phytase-like PF13449.6 KEY74699.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Esterase-like activity of phytase Reg_prop PF07494.11 KEY74699.1 - 0.19 12.0 0.4 10 6.7 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Fungal_trans PF04082.18 KEY74700.1 - 5.6e-49 166.6 2.6 7.8e-49 166.1 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEY74700.1 - 6.2e-09 35.8 14.0 9.6e-05 22.6 2.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEY74700.1 - 1.3e-05 25.6 11.1 0.01 16.6 1.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEY74700.1 - 0.0045 17.4 2.2 0.0045 17.4 2.2 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KEY74700.1 - 0.028 14.4 0.1 0.028 14.4 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEY74700.1 - 0.067 13.5 0.4 0.18 12.2 0.4 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEY74700.1 - 0.32 11.3 1.5 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Transp_cyt_pur PF02133.15 KEY74701.1 - 3.7e-92 309.4 37.3 4.3e-92 309.2 37.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_4 PF01565.23 KEY74704.1 - 3.7e-15 55.9 0.2 6.5e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY74704.1 - 0.0004 20.4 0.2 0.00086 19.4 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DSS1_SEM1 PF05160.13 KEY74706.1 - 0.064 13.3 0.1 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 DSS1/SEM1 family RNase_H PF00075.24 KEY74707.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 RNase H Sigma70_ner PF04546.13 KEY74707.1 - 0.12 12.3 9.6 0.18 11.7 9.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 KEY74707.1 - 0.2 10.8 15.4 0.27 10.3 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KEY74707.1 - 0.8 7.8 10.1 0.98 7.5 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEY74707.1 - 0.93 7.7 6.9 1.2 7.4 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KEY74707.1 - 0.95 9.5 5.6 1.6 8.8 5.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KEY74707.1 - 1.3 8.7 4.6 2.2 8.0 4.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 KEY74707.1 - 1.4 7.8 5.4 1.8 7.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YL1 PF05764.13 KEY74707.1 - 1.9 8.6 13.0 2.7 8.1 13.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 KEY74707.1 - 1.9 7.7 8.0 2.5 7.4 8.0 1.1 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 KEY74707.1 - 2.1 8.6 9.6 4.4 7.6 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.16 KEY74707.1 - 2.7 7.1 7.1 3.8 6.6 7.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 KEY74707.1 - 2.8 7.3 11.0 3.6 6.9 11.0 1.1 1 0 0 1 1 1 0 SDA1 Dicty_REP PF05086.12 KEY74707.1 - 5.1 4.9 4.8 6.5 4.6 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRAM PF02893.20 KEY74708.1 - 4.8e-32 110.2 1.0 3e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KEY74708.1 - 1.5e-29 102.8 0.0 3.5e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KEY74708.1 - 1.1e-13 51.6 0.0 3.3e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KEY74708.1 - 1.8e-07 30.4 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 KEY74708.1 - 6.4e-05 23.2 0.1 0.00033 20.9 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KEY74708.1 - 0.00014 22.3 0.8 0.0014 19.1 0.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KEY74708.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_2 PF08458.10 KEY74708.1 - 0.09 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region WD40 PF00400.32 KEY74709.1 - 5.1e-11 42.9 4.4 0.037 14.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat DpnD-PcfM PF14207.6 KEY74709.1 - 0.28 11.1 1.3 0.61 10.0 1.3 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein p450 PF00067.22 KEY74712.1 - 5.7e-45 153.9 0.0 6.5e-28 97.7 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 ORF_12_N PF18042.1 KEY74712.1 - 0.019 15.4 0.0 0.2 12.1 0.1 2.3 2 0 0 2 2 2 0 ORF 12 gene product N-terminal CLP1_P PF16575.5 KEY74712.1 - 0.12 12.1 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Epimerase PF01370.21 KEY74714.1 - 2.5e-19 69.7 0.1 4e-19 69.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY74714.1 - 7.5e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KEY74714.1 - 1.2e-07 31.6 0.1 3.7e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEY74714.1 - 3.2e-05 23.5 0.0 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEY74714.1 - 4.1e-05 22.7 0.0 8.7e-05 21.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEY74714.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KEY74714.1 - 0.019 14.1 0.2 0.47 9.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain LppA PF16708.5 KEY74714.1 - 0.099 12.6 0.2 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DapB_N PF01113.20 KEY74714.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus IDO PF01231.18 KEY74716.1 - 1.2e-07 31.0 1.0 3.9e-06 25.9 0.4 2.6 2 1 0 2 2 2 1 Indoleamine 2,3-dioxygenase CDP-OH_P_tran_2 PF08009.11 KEY74717.1 - 2.5 8.1 7.0 0.37 10.7 0.5 2.9 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 adh_short PF00106.25 KEY74718.1 - 5.1e-20 71.8 0.0 6.2e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74718.1 - 4.3e-14 52.6 0.0 5.3e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74718.1 - 2e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74718.1 - 8.4e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNA_pol_Rpb6 PF01192.22 KEY74718.1 - 0.0029 17.5 0.9 0.0061 16.5 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 3HCDH_N PF02737.18 KEY74718.1 - 0.0091 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KEY74718.1 - 0.02 14.8 0.2 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEY74718.1 - 0.021 14.0 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KEY74718.1 - 0.058 12.7 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2815 PF10991.8 KEY74718.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Vir_act_alpha_C PF10400.9 KEY74718.1 - 0.29 11.8 1.8 0.48 11.1 0.1 2.0 2 0 0 2 2 2 0 Virulence activator alpha C-term Lyase_1 PF00206.20 KEY74719.1 - 0.024 14.0 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Lyase Melibiase_2 PF16499.5 KEY74720.1 - 9.5e-55 185.8 2.3 3.4e-54 183.9 2.3 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KEY74720.1 - 1.6e-08 34.5 0.0 9.7e-08 32.0 0.0 2.3 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KEY74720.1 - 1.6e-06 27.3 0.0 3.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Melibiase Zn_clus PF00172.18 KEY74721.1 - 1.2e-06 28.5 9.4 2.1e-06 27.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEY74721.1 - 0.00026 19.9 0.5 0.00085 18.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 KEY74722.1 - 7.9e-53 179.8 0.0 1e-52 179.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEY74723.1 - 1.6e-33 116.1 28.8 1.6e-33 116.1 28.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF346 PF03984.13 KEY74724.1 - 0.003 17.3 48.9 0.008 15.9 1.3 7.2 7 0 0 7 7 7 5 Repeat of unknown function (DUF346) VCBS PF13517.6 KEY74724.1 - 0.032 14.8 0.8 0.032 14.8 0.8 4.5 4 2 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ank_2 PF12796.7 KEY74727.1 - 8.9e-65 215.3 0.0 1e-15 58.1 0.0 5.4 2 1 5 7 7 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY74727.1 - 7.7e-40 130.3 0.0 2.4e-05 24.4 0.0 10.7 10 0 0 10 10 9 6 Ankyrin repeat Ank_4 PF13637.6 KEY74727.1 - 8.8e-40 134.6 3.0 7e-09 36.1 0.0 7.0 4 1 3 7 7 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KEY74727.1 - 1.3e-35 120.3 0.0 3.6e-05 24.0 0.0 9.7 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KEY74727.1 - 5.7e-25 87.1 1.2 2.5e-06 27.6 0.0 6.3 4 1 2 6 6 6 6 Ankyrin repeats (many copies) RelA_SpoT PF04607.17 KEY74727.1 - 4.1e-09 36.7 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins NACHT PF05729.12 KEY74727.1 - 1.5e-07 31.5 0.1 5.1e-07 29.8 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY74727.1 - 1.3e-06 28.9 0.2 1.7e-05 25.2 0.1 2.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY74727.1 - 0.00031 21.0 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KEY74727.1 - 0.0022 17.3 0.0 0.024 13.9 0.1 2.3 1 1 1 2 2 2 1 KAP family P-loop domain ATPase_2 PF01637.18 KEY74727.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PH_8 PF15409.6 KEY74727.1 - 0.014 15.6 0.0 61 4.0 0.0 4.8 2 1 3 5 5 5 0 Pleckstrin homology domain Ribosomal_S6 PF01250.17 KEY74727.1 - 0.02 15.1 0.0 25 5.2 0.0 4.4 3 1 1 5 5 5 0 Ribosomal protein S6 RNA_helicase PF00910.22 KEY74727.1 - 0.073 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KEY74727.1 - 0.11 11.7 0.2 6.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Beta-lactamase PF00144.24 KEY74729.1 - 2.2e-36 125.8 0.1 3.5e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase PF00069.25 KEY74730.1 - 1.6e-24 86.7 0.0 2.7e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74730.1 - 3.8e-07 29.7 0.0 7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY74730.1 - 0.0027 17.7 0.1 0.19 11.6 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_31 PF01055.26 KEY74731.1 - 3.1e-115 385.9 4.5 4.5e-115 385.3 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KEY74731.1 - 4.5e-05 23.7 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KEY74731.1 - 6.6e-05 23.2 2.1 0.00026 21.2 0.2 3.0 3 1 0 3 3 3 1 Galactose mutarotase-like Fungal_trans_2 PF11951.8 KEY74732.1 - 3e-09 36.2 1.8 1.6e-08 33.7 0.8 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain PEP_mutase PF13714.6 KEY74734.1 - 9.8e-60 202.0 4.4 1.1e-59 201.8 4.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Tyrosinase PF00264.20 KEY74735.1 - 2.6e-41 142.4 2.4 4.3e-41 141.6 2.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4698 PF15769.5 KEY74736.1 - 0.62 9.1 2.6 0.72 8.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) CFEM PF05730.11 KEY74738.1 - 7.7e-12 45.1 7.3 1.3e-11 44.4 7.3 1.4 1 0 0 1 1 1 1 CFEM domain GST_N_3 PF13417.6 KEY74739.1 - 8.9e-09 35.7 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEY74739.1 - 4.2e-08 33.4 0.0 8.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEY74739.1 - 1.9e-05 24.6 0.5 3.4e-05 23.8 0.5 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEY74739.1 - 0.037 14.2 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEY74739.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEY74739.1 - 0.078 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 KEY74740.1 - 2.4e-18 66.9 0.0 6.1e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-RRN7 PF11781.8 KEY74740.1 - 0.4 10.4 1.6 0.8 9.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4212 PF13937.6 KEY74741.1 - 0.047 14.1 0.5 0.047 14.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) CFEM PF05730.11 KEY74742.1 - 0.00036 20.6 5.0 0.00036 20.6 5.0 2.4 2 0 0 2 2 2 1 CFEM domain CHD5 PF04420.14 KEY74742.1 - 0.19 11.6 0.2 0.26 11.1 0.2 1.2 1 0 0 1 1 1 0 CHD5-like protein APH PF01636.23 KEY74745.1 - 5.7e-10 39.5 0.1 7.7e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEY74745.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fungal_trans_2 PF11951.8 KEY74747.1 - 0.0022 16.9 1.5 0.0036 16.2 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74747.1 - 0.11 12.7 7.4 0.2 11.8 7.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.22 KEY74748.1 - 1.3e-16 60.6 0.2 1.7e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KEY74748.1 - 2.1e-05 24.2 0.0 5.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Cupin domain ABC2_membrane PF01061.24 KEY74751.1 - 2.4e-79 265.6 68.6 2.1e-41 141.7 26.9 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KEY74751.1 - 1.5e-34 119.5 1.1 2e-17 64.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KEY74751.1 - 1.6e-29 101.7 15.0 2e-26 91.7 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEY74751.1 - 5.4e-13 49.4 0.0 1.5e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEY74751.1 - 1.3e-07 32.2 0.2 0.00037 20.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KEY74751.1 - 1.3e-06 28.7 0.5 9.4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEY74751.1 - 9.3e-06 25.6 0.1 0.003 17.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEY74751.1 - 2.7e-05 23.8 1.1 0.00028 20.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEY74751.1 - 2.8e-05 23.8 2.1 0.0027 17.4 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEY74751.1 - 0.00062 20.1 1.2 0.4 11.0 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KEY74751.1 - 0.00066 19.6 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEY74751.1 - 0.001 19.6 0.1 0.0076 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEY74751.1 - 0.0037 17.3 0.1 4.2 7.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KEY74751.1 - 0.0045 16.7 0.6 0.43 10.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEY74751.1 - 0.0051 16.8 1.3 0.28 11.1 0.2 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KEY74751.1 - 0.0054 16.3 1.5 0.096 12.3 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KEY74751.1 - 0.012 16.1 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KEY74751.1 - 0.047 13.6 0.4 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SMC_N PF02463.19 KEY74751.1 - 0.05 13.0 0.2 8.7 5.7 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KEY74751.1 - 0.059 13.8 1.2 0.67 10.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KEY74751.1 - 0.088 13.0 1.0 0.41 10.9 0.4 2.2 2 0 0 2 2 2 0 AAA domain Apq12 PF12716.7 KEY74751.1 - 0.67 9.9 7.3 3 7.9 7.3 2.1 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis ABC2_membrane_3 PF12698.7 KEY74751.1 - 6.9 5.7 65.2 0.012 14.7 21.6 4.5 3 2 0 4 4 3 0 ABC-2 family transporter protein Glycos_transf_1 PF00534.20 KEY74752.1 - 1.5e-16 60.4 0.0 2.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEY74752.1 - 1e-11 45.4 0.0 2.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEY74752.1 - 0.0013 19.1 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sugar_tr PF00083.24 KEY74753.1 - 5.8e-85 285.8 22.4 7.1e-85 285.6 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY74753.1 - 1.8e-28 99.5 52.2 1.9e-27 96.1 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KEY74754.1 - 3.6e-61 206.7 0.0 5.3e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY74754.1 - 1.2e-47 162.8 0.0 2e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY74754.1 - 4.6e-13 49.1 0.0 1.2e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KEY74754.1 - 3.5e-11 43.1 0.0 6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain MBG PF17883.1 KEY74754.1 - 0.056 14.0 0.0 0.56 10.9 0.0 2.5 2 0 0 2 2 2 0 MBG domain FAD_binding_3 PF01494.19 KEY74755.1 - 3.4e-09 36.4 1.1 0.002 17.5 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KEY74755.1 - 0.029 13.6 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY74755.1 - 0.04 14.1 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KEY74755.1 - 0.11 11.6 0.0 9.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Peptidase_M20 PF01546.28 KEY74756.1 - 6.7e-28 97.8 0.0 8.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEY74756.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Fungal_trans PF04082.18 KEY74757.1 - 3.8e-18 65.5 5.9 2.5e-16 59.5 5.9 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74757.1 - 0.00099 19.2 1.9 0.002 18.2 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_C PF05193.21 KEY74757.1 - 0.098 12.7 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase M16 inactive domain Aldolase_II PF00596.21 KEY74758.1 - 2e-52 177.9 0.2 2.4e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.19 KEY74759.1 - 6.3e-40 136.4 0.0 8.8e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEY74759.1 - 2.9e-24 85.3 0.0 3.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KEY74759.1 - 0.024 15.2 1.2 0.17 12.5 0.8 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KEY74759.1 - 0.025 14.7 0.5 0.098 12.7 0.2 2.2 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KEY74759.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KEY74759.1 - 0.14 12.2 0.2 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KEY74760.1 - 1.9e-24 86.5 0.0 2.5e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74760.1 - 9.2e-10 38.7 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEY74760.1 - 5.9e-06 26.7 0.0 2.2e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEY74760.1 - 7.7e-06 25.5 0.1 0.00081 18.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY74760.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KEY74760.1 - 0.0036 17.2 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KEY74760.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LigB PF02900.18 KEY74761.1 - 5.9e-29 101.0 0.0 8.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PAH PF02671.21 KEY74761.1 - 0.71 10.1 2.4 13 6.0 2.4 2.3 1 1 0 1 1 1 0 Paired amphipathic helix repeat Zn_clus PF00172.18 KEY74762.1 - 1.4e-10 41.2 9.6 2.2e-10 40.5 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain USP19_linker PF16602.5 KEY74762.1 - 0.028 15.0 0.1 0.041 14.4 0.0 1.3 1 1 0 1 1 1 0 Linker region of USP19 deubiquitinase GCP_N_terminal PF17681.1 KEY74762.1 - 0.14 11.7 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Opy2 PF09463.10 KEY74762.1 - 0.19 12.1 5.9 0.48 10.8 1.9 2.2 2 0 0 2 2 2 0 Opy2 protein Fungal_trans PF04082.18 KEY74763.1 - 3.8e-11 42.5 0.0 6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KEY74764.1 - 0.00034 20.5 0.0 0.00034 20.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY74764.1 - 0.0088 15.8 0.0 0.009 15.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY74764.1 - 0.064 13.9 0.0 0.081 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Palm_thioest PF02089.15 KEY74765.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KEY74765.1 - 0.00054 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CorA PF01544.18 KEY74766.1 - 1.3e-08 34.5 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Beta_helix PF13229.6 KEY74770.1 - 4.1e-05 23.5 14.6 7e-05 22.7 11.2 2.2 1 1 1 2 2 2 2 Right handed beta helix region Na_H_Exchanger PF00999.21 KEY74771.1 - 1.6e-45 155.6 25.6 2.2e-45 155.1 25.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KEY74771.1 - 8.9 6.7 8.1 8.4 6.8 0.3 3.1 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family HCO3_cotransp PF00955.21 KEY74772.1 - 1.8e-57 195.3 16.7 1.3e-24 86.9 5.1 4.1 3 1 1 4 4 4 4 HCO3- transporter family SET PF00856.28 KEY74773.1 - 5.1e-08 33.5 0.0 9.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF4748 PF15932.5 KEY74773.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Glyco_transf_34 PF05637.12 KEY74774.1 - 3.6e-10 40.0 0.0 7.7e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.16 KEY74775.1 - 3.7e-31 108.3 27.6 5.4e-31 107.8 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 KEY74776.1 - 1.9e-37 128.6 0.0 2.2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 KEY74777.1 - 4.1e-08 33.2 8.2 9.3e-08 32.1 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY74777.1 - 0.00044 19.4 2.4 0.15 11.1 2.8 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Ferric_reduct PF01794.19 KEY74779.1 - 6e-15 55.5 19.3 6e-15 55.5 19.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEY74779.1 - 3.6e-06 27.2 1.5 0.071 13.2 0.1 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY74779.1 - 7.9e-06 25.9 0.0 0.00021 21.3 0.0 2.6 2 0 0 2 2 2 1 FAD-binding domain SpoVAC_SpoVAEB PF03862.13 KEY74779.1 - 0.0056 17.0 0.4 0.019 15.2 0.4 1.9 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein ketoacyl-synt PF00109.26 KEY74780.1 - 7.9e-54 182.9 0.1 7.4e-41 140.4 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEY74780.1 - 7.8e-40 135.6 0.2 1.5e-39 134.6 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY74780.1 - 1.5e-11 44.7 0.1 3.7e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension p450 PF00067.22 KEY74780.1 - 6.4e-11 41.7 0.0 9.9e-11 41.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Thiolase_N PF00108.23 KEY74780.1 - 0.039 13.3 0.1 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF1857 PF08982.11 KEY74781.1 - 1.1e-12 48.0 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Glyco_transf_28 PF03033.20 KEY74782.1 - 1.9e-23 83.1 0.0 6.1e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KEY74782.1 - 1.4e-05 24.1 0.1 2.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KEY74782.1 - 0.0011 18.8 0.2 0.0024 17.7 0.2 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KEY74782.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KEY74782.1 - 0.12 12.7 0.2 4 7.8 0.0 3.0 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain RTA1 PF04479.13 KEY74783.1 - 4.6e-64 215.8 6.9 5.5e-64 215.6 6.9 1.0 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_10 PF00331.20 KEY74784.1 - 4e-22 78.8 0.0 2.8e-16 59.6 0.0 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Glyco_hydro_61 PF03443.14 KEY74785.1 - 6.2e-47 160.2 0.1 7.5e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_4 PF08386.10 KEY74786.1 - 9.9e-19 67.4 0.0 2.5e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEY74786.1 - 1.4e-18 67.5 0.0 2.9e-17 63.2 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold VCPO_N PF17897.1 KEY74787.1 - 4.5e-81 271.7 0.4 6.8e-81 271.2 0.4 1.3 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 KEY74787.1 - 7.6e-11 41.9 0.0 2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 PAP2 superfamily TPR_12 PF13424.6 KEY74788.1 - 5.3e-16 58.7 0.1 3.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEY74788.1 - 6e-12 44.8 2.5 4.5e-06 26.2 0.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEY74788.1 - 4.3e-11 42.3 4.0 6.1e-06 25.9 0.3 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74788.1 - 8.9e-10 37.9 1.0 0.00049 20.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74788.1 - 1.9e-08 33.7 0.4 0.0069 16.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74788.1 - 3.5e-08 33.0 0.4 0.0015 18.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74788.1 - 1.1e-05 25.5 0.1 0.72 10.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74788.1 - 2e-05 25.1 0.3 0.04 14.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74788.1 - 0.00014 22.4 0.9 0.052 14.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEY74788.1 - 0.0017 18.3 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_17 PF13431.6 KEY74788.1 - 0.0018 18.5 0.1 0.99 9.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74788.1 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.7 2 1 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 KEY74788.1 - 0.02 15.5 1.7 1.3 9.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 KEY74788.1 - 0.037 14.3 0.3 7.6 7.0 0.0 3.0 2 1 1 3 3 3 0 PPR repeat L27 PF02828.16 KEY74788.1 - 0.11 12.2 0.1 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 L27 domain TPR_11 PF13414.6 KEY74788.1 - 0.53 10.0 5.7 0.75 9.5 0.3 3.1 3 1 1 4 4 4 0 TPR repeat TPR_12 PF13424.6 KEY74789.1 - 2.3e-124 405.9 25.4 1.3e-17 63.9 0.0 9.0 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KEY74789.1 - 1.7e-113 367.9 8.7 1.9e-12 46.6 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74789.1 - 6.1e-46 151.1 11.1 0.00059 19.7 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74789.1 - 6.1e-30 100.9 6.1 0.1 12.7 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74789.1 - 2e-29 101.9 1.0 0.0042 17.6 0.0 9.3 1 1 8 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KEY74789.1 - 8.4e-26 88.7 2.4 0.29 11.0 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74789.1 - 2.3e-23 82.5 0.0 0.0036 17.9 0.0 9.1 5 3 4 9 9 9 8 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74789.1 - 2.3e-23 80.3 0.5 0.43 11.4 0.0 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74789.1 - 5.1e-23 82.0 33.7 1e-10 41.5 6.0 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 KEY74789.1 - 4.7e-21 73.2 8.0 0.68 10.3 0.0 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74789.1 - 1.2e-16 59.9 14.0 2.5 9.1 0.0 10.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY74789.1 - 4.4e-14 51.8 15.4 0.71 10.4 0.0 9.0 9 0 0 9 9 8 4 Tetratricopeptide repeat PPR PF01535.20 KEY74789.1 - 2.4e-10 39.9 2.8 29 5.2 0.0 8.6 8 0 0 8 8 8 0 PPR repeat ANAPC3 PF12895.7 KEY74789.1 - 1.1e-09 38.4 3.3 0.94 9.7 0.0 7.2 1 1 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KEY74789.1 - 1.8e-09 37.9 0.6 26 5.1 0.0 7.2 1 1 7 8 8 8 0 Tetratrico peptide repeat TPR_6 PF13174.6 KEY74789.1 - 1.1e-08 35.1 18.3 18 6.2 0.0 10.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEY74789.1 - 1.1e-08 35.2 0.5 7.8 6.9 0.0 7.5 1 1 7 8 8 8 0 Tetratricopeptide repeat Spore_YpjB PF09577.10 KEY74789.1 - 1.2e-07 31.8 4.6 0.69 9.7 0.1 4.6 3 2 2 5 5 5 3 Sporulation protein YpjB (SpoYpjB) NACHT PF05729.12 KEY74789.1 - 3.4e-06 27.1 0.0 7.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF1897 PF09005.10 KEY74789.1 - 3.5e-05 23.2 4.9 14 5.3 0.1 6.8 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) RPN6_N PF18055.1 KEY74789.1 - 0.00046 20.5 8.9 5.2 7.5 0.1 5.0 1 1 6 7 7 7 1 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_25 PF13481.6 KEY74789.1 - 0.0029 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RBD-FIP PF09457.10 KEY74789.1 - 0.016 15.1 4.6 54 3.8 0.0 4.9 5 0 0 5 5 4 0 FIP domain TPR_3 PF07720.12 KEY74789.1 - 0.018 15.0 0.0 52 4.0 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 KEY74789.1 - 0.025 14.3 6.6 93 2.9 0.0 7.0 8 0 0 8 8 8 0 PPR repeat DUF5413 PF17434.2 KEY74789.1 - 0.032 14.5 1.2 46 4.4 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5413) AAA_16 PF13191.6 KEY74789.1 - 0.13 12.7 0.1 0.89 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain N36 PF11438.8 KEY74789.1 - 2.8 7.9 5.2 22 5.0 0.1 4.2 5 0 0 5 5 4 0 36-mer N-terminal peptide of the N protein (N36) TPR_11 PF13414.6 KEY74789.1 - 8.2 6.2 13.6 66 3.3 0.1 7.0 8 0 0 8 8 8 0 TPR repeat DnaJ PF00226.31 KEY74790.1 - 1.9e-16 59.9 0.1 2.6e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DDE_1 PF03184.19 KEY74791.1 - 9.8e-10 38.4 0.0 4.4e-09 36.2 0.0 2.1 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KEY74791.1 - 5.5e-05 23.1 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KEY74791.1 - 0.0086 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Syntaxin-6_N PF09177.11 KEY74791.1 - 0.027 15.0 0.8 0.38 11.3 0.1 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SKA1 PF07160.12 KEY74791.1 - 0.035 13.9 0.4 0.38 10.6 0.2 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RsbRD_N PF14361.6 KEY74791.1 - 0.14 12.9 1.2 0.63 10.8 0.2 2.4 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Allexi_40kDa PF05549.11 KEY74791.1 - 0.27 10.7 3.0 8.9 5.7 0.5 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Atg14 PF10186.9 KEY74791.1 - 1.1 8.3 5.3 11 5.0 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KEY74791.1 - 1.3 9.1 5.6 0.88 9.6 0.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3927 PF13064.6 KEY74792.1 - 0.024 14.6 0.4 0.024 14.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) CC190 PF15768.5 KEY74792.1 - 0.063 13.3 0.9 0.079 13.0 0.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 FAD_binding_4 PF01565.23 KEY74794.1 - 3.5e-11 43.0 0.2 5.6e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.26 KEY74795.1 - 6.6e-15 55.2 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY74795.1 - 0.00026 20.9 0.1 0.00061 19.6 0.1 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEY74795.1 - 0.029 15.4 0.0 0.05 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3328 PF11807.8 KEY74797.1 - 1.8e-27 96.6 0.0 2.1e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Corona_nucleoca PF00937.18 KEY74798.1 - 0.015 14.4 0.9 0.016 14.3 0.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Glyco_hydro_11 PF00457.17 KEY74799.1 - 7e-49 165.9 1.6 8.6e-49 165.6 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_7 PF00840.20 KEY74800.1 - 7.1e-137 456.7 0.6 9.7e-137 456.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_C65 PF10275.9 KEY74800.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Cyt-b5 PF00173.28 KEY74801.1 - 2.2e-13 50.1 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KEY74801.1 - 1.4e-10 40.6 0.0 1.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KEY74801.1 - 1.2e-09 38.1 0.0 1.7e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KEY74801.1 - 1.8e-06 28.5 0.0 5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ketoacyl-synt PF00109.26 KEY74802.1 - 2.5e-78 263.2 0.0 4.6e-78 262.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KEY74802.1 - 2.1e-56 191.3 0.0 6.6e-56 189.7 0.0 1.9 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KEY74802.1 - 4.5e-36 125.0 0.0 1e-35 123.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY74802.1 - 4.3e-28 97.7 0.1 8.5e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEY74802.1 - 1.4e-22 79.8 5.3 4.2e-11 43.0 0.2 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KEY74802.1 - 8.7e-19 67.7 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 KEY74802.1 - 5.9e-10 39.6 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY74802.1 - 7.8e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RmlD_sub_bind PF04321.17 KEY74802.1 - 0.014 14.5 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEY74802.1 - 0.03 13.5 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEY74802.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF915 PF06028.11 KEY74802.1 - 0.093 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ketoacyl-synt PF00109.26 KEY74803.1 - 2.1e-75 253.6 0.0 3.5e-75 252.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEY74803.1 - 3.1e-59 199.9 0.1 7e-59 198.8 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEY74803.1 - 8.9e-49 166.3 0.0 1.5e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEY74803.1 - 9.6e-41 140.3 0.0 1.9e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY74803.1 - 1.5e-38 131.4 0.5 1.5e-38 131.4 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KEY74803.1 - 1.6e-17 64.8 0.0 1.1e-16 62.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEY74803.1 - 2.3e-17 63.2 0.0 8.2e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KEY74803.1 - 1.9e-16 60.5 0.0 1.8e-15 57.4 0.0 2.5 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEY74803.1 - 2.6e-10 40.1 0.1 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74803.1 - 1.1e-07 31.7 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KEY74803.1 - 0.00063 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KEY74803.1 - 0.00067 20.0 0.0 0.0032 17.8 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KEY74803.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 KEY74803.1 - 0.076 12.9 0.1 0.27 11.1 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans_2 PF11951.8 KEY74804.1 - 9.7e-06 24.6 0.2 2.7e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 KEY74805.1 - 2.3e-21 76.1 1.2 3.9e-20 72.1 0.5 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74805.1 - 3.3e-15 56.3 0.3 1.3e-11 44.6 0.3 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74805.1 - 7.3e-10 39.0 0.2 1.2e-09 38.3 0.2 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KEY74806.1 - 9e-45 153.1 30.9 9e-45 153.1 30.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SnoaL_4 PF13577.6 KEY74807.1 - 2.3e-13 50.4 0.4 2.8e-13 50.1 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KEY74807.1 - 0.012 16.3 0.1 0.027 15.1 0.1 1.7 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KEY74807.1 - 0.018 15.4 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 KEY74807.1 - 0.1 13.3 0.0 0.2 12.3 0.0 1.6 1 1 0 1 1 1 0 Putative lumazine-binding AflR PF08493.10 KEY74808.1 - 0.002 17.7 0.1 0.002 17.7 0.1 2.1 2 0 0 2 2 2 1 Aflatoxin regulatory protein p450 PF00067.22 KEY74809.1 - 2.7e-74 250.6 0.1 3.2e-74 250.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_2 PF04748.13 KEY74809.1 - 0.092 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Questin_oxidase PF14027.6 KEY74810.1 - 1e-78 265.3 0.0 1.2e-78 265.1 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like FAD_binding_3 PF01494.19 KEY74811.1 - 2e-75 254.2 0.0 2.9e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY74811.1 - 2.6e-08 33.9 1.7 8.1e-05 22.4 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY74811.1 - 0.00013 21.3 0.0 0.00055 19.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY74811.1 - 0.00034 21.1 0.1 0.0048 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY74811.1 - 0.00068 19.0 0.2 0.0011 18.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY74811.1 - 0.0007 19.8 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY74811.1 - 0.0014 18.0 0.2 0.0035 16.8 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEY74811.1 - 0.0021 17.2 1.5 0.0029 16.8 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEY74811.1 - 0.016 14.5 0.0 0.038 13.2 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KEY74811.1 - 0.042 12.6 0.2 0.069 11.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 KEY74811.1 - 0.082 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 KEY74812.1 - 4.8e-14 52.0 1.0 9.8e-14 51.0 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74812.1 - 0.0072 16.4 3.6 0.014 15.5 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KEY74813.1 - 3.9e-15 55.8 0.0 8.8e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEY74813.1 - 6.5e-09 36.0 0.0 1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEY74813.1 - 3.5e-05 23.5 0.0 6.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_10 PF00331.20 KEY74814.1 - 2.6e-99 332.4 0.3 2.9e-99 332.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.18 KEY74814.1 - 0.0086 14.5 0.5 0.019 13.4 0.2 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 1 PhyH PF05721.13 KEY74815.1 - 3.6e-07 30.6 0.0 2e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 KEY74816.1 - 3.6e-08 33.4 9.1 6.9e-08 32.5 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KEY74816.1 - 0.0075 16.0 1.3 0.017 14.8 1.3 1.6 1 0 0 1 1 1 1 Integrin plexin domain TPR_12 PF13424.6 KEY74817.1 - 1.3e-15 57.4 16.7 3e-05 24.2 0.3 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74817.1 - 2e-05 24.3 5.4 0.48 10.6 0.6 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KEY74817.1 - 3.6e-05 24.2 0.2 0.00013 22.4 0.2 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEY74817.1 - 5.6e-05 23.4 0.0 0.00027 21.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEY74817.1 - 0.00012 22.0 0.1 0.00038 20.4 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KEY74817.1 - 0.015 15.9 0.0 0.069 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 KEY74817.1 - 0.018 14.9 14.3 2.9 7.9 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_30 PF13604.6 KEY74817.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 KEY74817.1 - 0.63 11.0 12.9 1.5e+02 3.7 1.2 7.9 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74817.1 - 2 9.1 6.2 7.7 7.3 1.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74817.1 - 4.6 8.2 7.7 13 6.8 0.9 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Transferase PF02458.15 KEY74818.1 - 0.03 13.0 0.0 0.48 9.0 0.0 2.1 2 0 0 2 2 2 0 Transferase family Carn_acyltransf PF00755.20 KEY74819.1 - 2.1e-100 337.1 0.0 1e-99 334.8 0.0 2.1 3 0 0 3 3 3 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KEY74819.1 - 4.6e-74 249.2 0.1 1.5e-73 247.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY74819.1 - 1.8e-52 178.9 1.2 3e-52 178.1 1.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY74819.1 - 2.7e-47 161.0 0.0 7.6e-47 159.5 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEY74819.1 - 3e-45 154.7 0.0 6.8e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEY74819.1 - 2.7e-36 124.2 0.1 7.8e-36 122.7 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KEY74819.1 - 2.2e-18 67.6 0.1 1.8e-16 61.4 0.0 3.8 4 0 0 4 4 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KEY74819.1 - 2.7e-17 63.3 0.0 9.4e-17 61.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEY74819.1 - 3.9e-17 62.7 0.2 3.9e-16 59.5 0.2 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KEY74819.1 - 5.9e-12 45.7 0.0 4e-11 43.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KEY74819.1 - 5.5e-10 39.8 0.1 7.5e-09 36.2 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KEY74819.1 - 9.5e-09 35.0 0.0 6e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KEY74819.1 - 1e-08 35.7 0.0 3.5e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY74819.1 - 2.2e-08 34.1 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEY74819.1 - 2.4e-06 27.8 0.2 1.1e-05 25.7 0.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KEY74819.1 - 3.5e-06 26.9 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KEY74819.1 - 0.0001 22.1 0.6 0.00025 20.9 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KEY74819.1 - 0.0024 17.3 0.0 0.0073 15.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KEY74819.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KEY74819.1 - 0.019 14.7 1.1 0.089 12.5 1.1 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KEY74819.1 - 0.073 12.9 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF982 PF06169.12 KEY74819.1 - 0.12 12.4 0.6 1.3 9.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Pkinase PF00069.25 KEY74820.1 - 5e-51 173.6 0.0 6.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74820.1 - 1.2e-31 109.9 0.0 1.6e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEY74820.1 - 0.00013 22.0 0.1 0.081 12.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KEY74820.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEY74820.1 - 0.027 13.8 0.1 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEY74820.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 KEY74820.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family E1-E2_ATPase PF00122.20 KEY74821.1 - 3.2e-37 127.8 20.9 6.1e-32 110.6 0.8 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEY74821.1 - 5.5e-26 91.4 7.3 5.5e-26 91.4 7.3 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEY74821.1 - 1.2e-19 71.5 0.0 5.7e-18 66.0 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEY74821.1 - 2.2e-18 65.7 0.8 7e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEY74821.1 - 2.6e-18 65.9 0.0 8e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEY74821.1 - 3.8e-05 23.5 0.2 0.0024 17.7 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEY74821.1 - 0.027 14.9 0.2 0.18 12.2 0.2 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Myb_DNA-binding PF00249.31 KEY74822.1 - 1.4e-12 47.6 0.6 2.2e-07 31.0 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEY74822.1 - 2.2e-09 37.4 0.2 0.00031 20.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain FOXP-CC PF16159.5 KEY74822.1 - 0.0046 17.5 0.9 0.012 16.3 0.9 1.6 1 0 0 1 1 1 1 FOXP coiled-coil domain SANT_DAMP1_like PF16282.5 KEY74822.1 - 0.016 15.4 0.3 0.033 14.4 0.3 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Peptidase_C50 PF03568.17 KEY74822.1 - 0.023 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 SLIDE PF09111.10 KEY74822.1 - 0.093 12.8 0.1 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 SLIDE Fungal_trans PF04082.18 KEY74823.1 - 1.2e-28 100.0 0.1 2.1e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74823.1 - 5e-11 42.5 12.6 8.6e-11 41.8 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-gua_Ptrans PF00217.19 KEY74823.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Exo_endo_phos PF03372.23 KEY74824.1 - 9.4e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_28 PF00295.17 KEY74826.1 - 6.3e-47 160.2 1.0 1.1e-46 159.4 1.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.31 KEY74827.1 - 0.011 16.0 0.0 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain MFS_1 PF07690.16 KEY74828.1 - 3.3e-44 151.2 23.8 3.3e-44 151.2 23.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY74828.1 - 1.1e-10 41.0 9.5 1.1e-10 41.0 9.5 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEY74828.1 - 1.7e-06 26.7 1.8 3.2e-06 25.9 1.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEY74828.1 - 0.0061 14.9 7.9 0.018 13.3 3.9 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 KEY74828.1 - 0.058 13.1 0.2 0.058 13.1 0.2 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KEY74828.1 - 0.39 9.5 10.1 0.027 13.4 0.9 2.6 2 1 0 2 2 2 0 MFS_1 like family DEAD PF00270.29 KEY74829.1 - 1.7e-15 57.2 0.0 3.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEY74829.1 - 7.9e-12 45.5 0.0 4.2e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEY74829.1 - 6e-06 26.6 0.1 1.6e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KEY74829.1 - 0.01 15.3 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SPAM PF02090.15 KEY74829.1 - 0.031 14.1 4.5 0.26 11.1 1.6 2.5 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein NmrA PF05368.13 KEY74830.1 - 7.1e-19 68.3 0.0 9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74830.1 - 5.6e-15 55.7 0.0 8.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEY74830.1 - 1.6e-06 28.4 0.1 2.7e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEY74830.1 - 8.3e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KEY74830.1 - 0.00094 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KEY74830.1 - 0.0073 15.5 0.0 0.015 14.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein DapB_N PF01113.20 KEY74830.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KEY74830.1 - 0.02 15.6 1.0 0.045 14.5 0.4 2.0 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aminotran_3 PF00202.21 KEY74831.1 - 1.1e-53 182.3 0.0 2.2e-51 174.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.8 KEY74832.1 - 4.6e-36 124.5 3.4 6.2e-36 124.0 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Borrelia_REV PF03978.13 KEY74832.1 - 0.016 15.2 0.0 9.6 6.1 0.0 3.0 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein NmrA PF05368.13 KEY74833.1 - 7.3e-30 104.2 0.1 1.1e-29 103.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74833.1 - 9.1e-24 84.4 0.0 1.6e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY74833.1 - 0.00016 21.2 0.0 0.0031 17.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 KEY74834.1 - 0.00051 20.6 0.6 0.0092 16.5 0.0 3.0 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) SesA PF17107.5 KEY74834.1 - 0.011 16.0 1.5 0.47 10.7 0.1 2.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 KEY74834.1 - 0.018 15.6 0.6 43 4.8 0.0 4.3 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74834.1 - 0.075 13.6 0.4 7.3 7.5 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat zf-C4H2 PF10146.9 KEY74834.1 - 0.12 12.6 3.5 0.16 12.2 1.4 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein Fez1 PF06818.15 KEY74834.1 - 0.23 11.9 4.1 0.15 12.5 0.5 2.1 1 1 1 2 2 2 0 Fez1 DUF1640 PF07798.11 KEY74834.1 - 0.87 9.6 4.5 0.36 10.9 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GAF_2 PF13185.6 KEY74836.1 - 0.13 12.6 0.0 3.5 7.9 0.0 2.0 1 1 1 2 2 2 0 GAF domain Fungal_trans_2 PF11951.8 KEY74837.1 - 2e-08 33.4 0.1 3.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74837.1 - 7e-08 32.5 3.5 1.6e-07 31.3 3.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM52 PF14979.6 KEY74837.1 - 0.0065 16.4 0.2 3.6 7.5 0.1 2.4 2 0 0 2 2 2 2 Transmembrane 52 Asp PF00026.23 KEY74838.1 - 5.1e-39 134.6 0.0 7.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEY74838.1 - 4.6e-06 27.0 0.0 2.9e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEY74838.1 - 4.4e-05 24.0 0.9 1 10.0 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KEY74838.1 - 0.00075 20.0 0.1 0.32 11.6 0.1 3.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease MIP PF00230.20 KEY74839.1 - 9.6e-28 97.4 10.5 1.1e-27 97.2 10.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1279 PF06916.13 KEY74839.1 - 0.027 15.0 0.5 0.044 14.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Cytochrom_B558a PF05038.13 KEY74839.1 - 1.4 8.4 4.1 3.2 7.3 4.1 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit HET PF06985.11 KEY74841.1 - 1.4e-23 83.9 0.0 4.2e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 KEY74844.1 - 4.1e-39 131.4 1.7 2e-12 46.6 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEY74844.1 - 1.4e-29 102.2 0.6 3.7e-16 59.2 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74844.1 - 1e-16 59.6 0.2 0.00027 20.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74844.1 - 1.1e-07 31.4 0.0 0.3 11.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY74844.1 - 1.4e-07 31.0 0.0 0.41 10.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74844.1 - 1.9e-07 31.6 0.0 0.0037 17.9 0.0 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY74844.1 - 1.3e-06 28.4 2.9 0.52 10.8 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74844.1 - 1.3e-05 25.6 0.9 0.036 14.6 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74844.1 - 0.00014 21.4 0.6 0.00065 19.2 0.4 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KEY74844.1 - 0.00049 20.1 1.3 8 7.0 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74844.1 - 0.00065 20.3 5.0 1 10.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74844.1 - 0.0079 16.7 10.4 9.7 7.1 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_5 PF12688.7 KEY74844.1 - 0.0093 16.2 0.0 26 5.1 0.0 3.4 1 1 2 3 3 3 0 Tetratrico peptide repeat TPR_6 PF13174.6 KEY74844.1 - 0.22 12.2 3.8 30 5.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF948 PF06103.11 KEY74845.1 - 0.019 15.2 2.8 0.024 14.9 2.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ANAPC4 PF12896.7 KEY74845.1 - 0.037 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Cluap1 PF10234.9 KEY74845.1 - 0.042 13.3 1.0 0.05 13.0 1.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Syntaxin_2 PF14523.6 KEY74845.1 - 0.1 13.0 1.8 0.33 11.3 1.8 1.7 1 1 0 1 1 1 0 Syntaxin-like protein Dimer_Tnp_hAT PF05699.14 KEY74846.1 - 1.7e-22 79.0 0.3 3.1e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RSN1_7TM PF02714.15 KEY74850.1 - 4.9e-79 265.5 21.0 4.9e-79 265.5 21.0 2.3 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY74850.1 - 4.8e-37 127.1 1.5 4.8e-37 127.1 1.5 2.4 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEY74850.1 - 1.6e-26 93.6 0.3 2.6e-26 92.9 0.3 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEY74850.1 - 1.2e-20 73.4 0.1 2.6e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter TFIIF_beta_N PF17683.1 KEY74850.1 - 0.042 14.5 0.3 0.083 13.6 0.3 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus DUF4064 PF13273.6 KEY74850.1 - 0.72 10.2 0.0 0.72 10.2 0.0 4.7 5 1 0 5 5 5 0 Protein of unknown function (DUF4064) DDE_Tnp_1_7 PF13843.6 KEY74852.1 - 3e-23 82.7 0.0 3.5e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 bZIP_1 PF00170.21 KEY74853.1 - 1.8e-10 40.7 7.6 4e-10 39.6 7.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEY74853.1 - 3.2e-05 23.9 4.4 3.2e-05 23.9 4.4 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEY74853.1 - 0.016 15.7 4.2 0.016 15.7 4.2 2.1 1 1 0 1 1 1 0 bZIP Maf transcription factor Sin3a_C PF16879.5 KEY74853.1 - 0.28 10.9 6.7 0.2 11.3 3.1 2.0 1 1 1 2 2 2 0 C-terminal domain of Sin3a protein Zn_clus PF00172.18 KEY74854.1 - 0.0084 16.2 1.3 0.015 15.4 1.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5082 PF16888.5 KEY74854.1 - 0.12 12.6 0.1 5.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) zf-C2H2 PF00096.26 KEY74855.1 - 0.0003 21.1 16.9 2.3 8.8 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2HE PF16278.5 KEY74855.1 - 0.0018 18.7 0.8 0.14 12.7 0.1 2.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-TAZ PF02135.16 KEY74855.1 - 0.022 15.2 3.4 0.096 13.2 2.0 2.3 2 0 0 2 2 2 0 TAZ zinc finger SAT PF16073.5 KEY74855.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Pox_G9-A16 PF03003.16 KEY74855.1 - 0.1 12.3 1.1 0.21 11.3 1.1 1.5 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 zf-C2H2_4 PF13894.6 KEY74855.1 - 0.14 13.1 19.2 2.6 9.1 0.2 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KEY74855.1 - 0.15 12.7 3.7 5 7.8 0.7 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain CxC6 PF18721.1 KEY74855.1 - 0.52 10.6 4.5 5.1 7.4 5.0 2.4 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Myb_DNA-bind_3 PF12776.7 KEY74856.1 - 1.6e-07 32.2 0.3 3e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PNP_UDP_1 PF01048.20 KEY74857.1 - 1.1e-11 44.5 0.1 2.1e-11 43.6 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily GP67 PF17634.2 KEY74858.1 - 0.00055 20.3 3.6 0.00065 20.0 3.6 1.2 1 0 0 1 1 1 1 Gene product 67 DUF4611 PF15387.6 KEY74858.1 - 0.0057 16.8 1.0 0.0068 16.6 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) NOA36 PF06524.12 KEY74858.1 - 0.17 11.2 2.9 0.17 11.2 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KEY74858.1 - 0.49 10.8 10.2 0.7 10.3 10.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Profilin PF00235.19 KEY74859.1 - 4.7e-35 120.6 2.2 3.5e-33 114.6 2.2 2.0 1 1 0 1 1 1 1 Profilin Got1 PF04178.12 KEY74860.1 - 2.1e-14 53.9 12.1 2.8e-14 53.5 12.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family YL1_C PF08265.11 KEY74861.1 - 2.4e-16 59.2 0.1 4.3e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BASP1 PF05466.12 KEY74861.1 - 4.1 7.4 6.4 6.1 6.8 6.0 1.5 1 1 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DASH_Dad4 PF08650.10 KEY74862.1 - 5.4e-32 109.6 6.3 6e-32 109.4 6.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KEY74862.1 - 0.031 14.4 0.6 0.037 14.2 0.6 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Biotin_carb_C PF02785.19 KEY74862.1 - 0.038 14.1 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Actin PF00022.19 KEY74863.1 - 9.4e-55 185.9 0.0 4e-52 177.2 0.0 2.3 1 1 0 1 1 1 1 Actin bZIP_1 PF00170.21 KEY74864.1 - 1.1e-07 31.8 12.8 1.7e-07 31.2 10.0 2.5 2 1 0 2 2 2 1 bZIP transcription factor DUF2564 PF10819.8 KEY74864.1 - 0.1 13.0 6.4 0.15 12.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Prominin PF05478.11 KEY74864.1 - 0.17 9.8 0.0 0.24 9.3 0.0 1.1 1 0 0 1 1 1 0 Prominin bZIP_2 PF07716.15 KEY74864.1 - 0.34 11.0 11.1 61 3.8 11.1 2.6 1 1 0 1 1 1 0 Basic region leucine zipper TPR_10 PF13374.6 KEY74865.1 - 7.1e-66 216.5 0.3 2.4e-12 46.3 0.0 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEY74865.1 - 2.7e-58 194.2 0.2 2.9e-15 56.3 0.0 5.7 2 1 4 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74865.1 - 5.3e-24 82.4 2.3 0.00067 19.5 0.0 7.0 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74865.1 - 7.5e-13 47.5 1.1 0.56 10.5 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEY74865.1 - 1.2e-11 43.9 0.0 0.34 10.8 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74865.1 - 2.2e-09 37.2 3.4 2.1e-08 34.0 2.0 2.4 1 1 1 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 KEY74865.1 - 4.8e-09 36.7 0.0 3.5 8.4 0.0 5.6 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY74865.1 - 1.4e-08 34.5 0.0 1.7 9.2 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74865.1 - 1.1e-07 32.3 0.0 0.48 11.0 0.0 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74865.1 - 1.4e-07 31.4 0.0 37 5.3 0.0 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74865.1 - 8.8e-07 28.7 3.5 4.4 7.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74865.1 - 6.4e-06 26.6 0.1 40 5.4 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat IL34 PF15036.6 KEY74865.1 - 0.00084 19.4 2.8 7.7 6.5 0.0 4.5 2 1 3 5 5 4 1 Interleukin 34 Helo_like_N PF17111.5 KEY74865.1 - 0.002 17.5 0.5 0.0055 16.1 0.4 1.8 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins ANAPC3 PF12895.7 KEY74865.1 - 0.0048 17.1 0.0 10 6.4 0.0 4.1 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KEY74865.1 - 0.0078 16.2 0.0 49 4.1 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 KEY74865.1 - 0.0092 16.2 2.3 41 4.7 0.1 5.5 6 0 0 6 6 6 0 PPR repeat Citrate_ly_lig PF08218.11 KEY74865.1 - 0.014 15.0 0.2 17 5.0 0.0 3.9 2 1 1 4 4 4 0 Citrate lyase ligase C-terminal domain Chlorosome_CsmC PF11098.8 KEY74865.1 - 0.025 14.5 0.3 0.066 13.2 0.3 1.7 1 0 0 1 1 1 0 Chlorosome envelope protein C PepSY_like PF11396.8 KEY74865.1 - 0.088 13.4 6.2 55 4.4 0.1 4.6 5 0 0 5 5 4 0 Putative beta-lactamase-inhibitor-like, PepSY-like cwf21 PF08312.12 KEY74865.1 - 1.8 8.8 8.1 4 7.7 2.3 3.4 1 1 2 3 3 3 0 cwf21 domain N36 PF11438.8 KEY74865.1 - 7.1 6.6 9.4 48 3.9 0.1 4.6 5 0 0 5 5 5 0 36-mer N-terminal peptide of the N protein (N36) DDE_Tnp_1_7 PF13843.6 KEY74866.1 - 6.1e-27 94.8 0.0 8.1e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 eIF-3_zeta PF05091.12 KEY74866.1 - 4 6.3 6.5 5.6 5.8 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PNP_UDP_1 PF01048.20 KEY74867.1 - 2.9e-11 43.1 0.0 6.2e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1541 PF07563.11 KEY74867.1 - 0.0042 16.9 0.1 0.0078 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1541) AAA_16 PF13191.6 KEY74867.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY74867.1 - 0.18 12.0 0.0 1.6 9.0 0.0 2.4 2 1 1 3 3 3 0 AAA domain rpo132 PF12415.8 KEY74868.1 - 0.095 12.0 0.1 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Pro_Al_protease PF02983.14 KEY74870.1 - 1.4e-11 44.3 0.1 1.4e-11 44.3 0.1 2.4 2 1 0 2 2 2 1 Alpha-lytic protease prodomain DDE_Tnp_1_7 PF13843.6 KEY74873.1 - 4e-09 36.2 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 MFMR_assoc PF16596.5 KEY74873.1 - 0.0051 17.3 4.2 0.0072 16.8 4.2 1.2 1 0 0 1 1 1 1 Disordered region downstream of MFMR F-box-like PF12937.7 KEY74876.1 - 0.0053 16.6 0.5 0.026 14.4 0.5 2.2 2 0 0 2 2 2 1 F-box-like zf-CCHC_2 PF13696.6 KEY74877.1 - 0.0024 17.6 1.3 0.0048 16.7 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KEY74877.1 - 0.0055 17.0 0.1 0.017 15.4 0.1 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KEY74877.1 - 0.039 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Sugarporin_N PF11471.8 KEY74877.1 - 0.069 13.1 1.6 0.15 12.1 1.6 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-CCHC PF00098.23 KEY74877.1 - 0.53 10.5 2.6 0.9 9.7 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S14 PF00253.21 KEY74877.1 - 0.55 10.0 3.7 1.5 8.6 3.7 1.8 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e RT_RNaseH PF17917.1 KEY74878.1 - 5e-29 100.7 0.0 9.2e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KEY74878.1 - 4.3e-17 62.0 0.0 7.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CLZ PF16526.5 KEY74878.1 - 0.1 12.9 0.3 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ank_2 PF12796.7 KEY74879.1 - 5.7e-100 328.1 74.1 4.4e-13 49.6 1.1 9.4 2 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74879.1 - 3.9e-69 228.2 25.2 1.1e-07 32.2 0.1 14.5 4 3 9 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 KEY74879.1 - 2.2e-58 192.3 60.7 3.8e-07 30.3 0.2 19.1 19 0 0 19 19 19 17 Ankyrin repeat Ank_3 PF13606.6 KEY74879.1 - 5.1e-46 149.3 30.0 0.00088 19.6 0.0 19.1 19 0 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.6 KEY74879.1 - 8e-38 128.0 34.1 1.9e-05 24.9 0.7 15.2 4 3 15 19 19 19 16 Ankyrin repeats (many copies) NACHT PF05729.12 KEY74879.1 - 6.5e-11 42.4 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KEY74879.1 - 3.4e-08 33.0 3.2 1.1e-07 31.4 2.0 2.4 2 1 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 KEY74879.1 - 0.0001 22.8 0.1 0.00049 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KEY74879.1 - 0.015 15.9 0.0 0.045 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEY74879.1 - 0.085 13.1 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain MFMR_assoc PF16596.5 KEY74880.1 - 0.021 15.3 1.7 0.043 14.3 1.7 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR YcaO PF02624.16 KEY74880.1 - 0.045 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Nop14 PF04147.12 KEY74880.1 - 1.8 6.6 8.5 2.4 6.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_1_7 PF13843.6 KEY74881.1 - 1.2e-32 113.6 0.0 2.7e-32 112.5 0.0 1.5 1 1 0 1 1 1 1 Transposase IS4 Ank_2 PF12796.7 KEY74882.1 - 2.9e-18 66.2 8.2 1.5e-10 41.5 0.7 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEY74882.1 - 1.5e-13 50.5 2.8 0.018 15.5 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 KEY74882.1 - 1e-12 48.3 0.1 2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KEY74882.1 - 1.8e-12 47.5 0.2 2.8e-06 27.8 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KEY74882.1 - 1.2e-08 34.5 0.1 4.1e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_3 PF13606.6 KEY74882.1 - 8.8e-07 28.8 0.3 1.2 10.0 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KEY74882.1 - 2.1e-06 27.9 2.3 0.017 15.4 0.2 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KEY74882.1 - 2.8e-06 27.8 0.8 1.9e-05 25.1 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KEY74882.1 - 0.01 15.0 0.2 0.046 12.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KEY74882.1 - 0.13 12.8 0.0 0.82 10.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF1966 PF09260.11 KEY74882.1 - 0.16 12.3 0.2 26 5.2 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1966) AAA_22 PF13401.6 KEY74882.1 - 0.16 12.3 0.0 0.57 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Fungal_trans_2 PF11951.8 KEY74884.1 - 9.7e-05 21.3 0.4 0.00016 20.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 KEY74885.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEY74885.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) NmrA PF05368.13 KEY74886.1 - 5.8e-23 81.7 0.0 7.5e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74886.1 - 1.3e-15 57.7 0.0 2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY74886.1 - 5.9e-07 29.2 0.4 5.2e-05 22.8 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEY74886.1 - 0.00075 18.7 0.1 0.0013 17.9 0.0 1.4 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KEY74886.1 - 0.0032 16.5 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEY74886.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEY74886.1 - 0.021 13.9 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KEY74886.1 - 0.028 14.7 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEY74886.1 - 0.1 12.9 0.1 0.25 11.6 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KEY74886.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 KEY74886.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEY74886.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KEY74886.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KEY74887.1 - 5.4e-44 150.2 0.0 8.6e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KEY74887.1 - 4e-10 39.9 0.0 1.2e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.25 KEY74887.1 - 0.0019 17.7 0.1 0.0057 16.1 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase ketoacyl-synt PF00109.26 KEY74888.1 - 1.5e-82 277.0 0.2 3e-82 276.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY74888.1 - 3.1e-65 220.8 0.2 7.6e-65 219.5 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEY74888.1 - 5.6e-39 132.8 2.6 1.5e-38 131.4 2.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KEY74888.1 - 2.2e-08 33.7 0.0 9.4e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KEY74888.1 - 2.2e-08 34.5 0.0 6.2e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEY74888.1 - 2.9e-05 23.6 0.1 0.0001 21.8 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain PriA_C PF18074.1 KEY74888.1 - 0.028 15.2 0.1 0.073 13.9 0.1 1.7 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain ACP_syn_III PF08545.10 KEY74888.1 - 0.27 11.1 1.8 4.9 7.1 1.5 3.3 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UbiA PF01040.18 KEY74889.1 - 1.6e-37 129.2 24.9 2e-37 128.9 24.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Stig1 PF04885.13 KEY74890.1 - 9.3e-49 165.5 107.5 5.3e-13 49.6 7.7 7.6 1 1 5 6 6 6 5 Stigma-specific protein, Stig1 TPR_10 PF13374.6 KEY74892.1 - 1.3e-30 104.4 0.0 3.3e-11 42.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEY74892.1 - 2.5e-19 69.3 0.0 4.5e-11 42.9 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74892.1 - 4.1e-08 32.7 0.0 0.0035 17.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74892.1 - 0.00036 20.5 0.0 0.61 10.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74892.1 - 0.0011 19.4 0.4 8.8 7.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74892.1 - 0.0018 18.2 0.0 2.1 8.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74892.1 - 0.0019 18.8 0.5 2.2 9.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74892.1 - 0.0049 16.3 0.5 0.0094 15.4 0.5 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 KEY74892.1 - 0.019 14.8 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NB-ARC PF00931.22 KEY74893.1 - 5.4e-05 22.5 0.0 8.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEY74893.1 - 0.00027 21.2 0.0 0.0014 19.0 0.0 2.1 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.7 KEY74893.1 - 0.0019 18.9 1.4 0.0042 17.7 1.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KEY74893.1 - 0.0026 18.2 0.4 0.009 16.4 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KEY74893.1 - 0.0038 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin DUF676 PF05057.14 KEY74893.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_30 PF13604.6 KEY74893.1 - 0.017 14.8 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEY74893.1 - 0.087 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KEY74895.1 - 9.2e-91 295.3 50.8 9.3e-12 45.3 1.6 9.7 9 0 0 9 9 9 8 WD domain, G-beta repeat NACHT_N PF17100.5 KEY74895.1 - 1.2e-77 260.7 0.8 1.2e-77 260.7 0.8 1.6 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KEY74895.1 - 2.8e-27 94.8 11.4 0.0033 17.7 0.0 8.0 1 1 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY74895.1 - 2.5e-17 63.3 0.2 1.9e-16 60.4 0.0 2.5 4 0 0 4 4 4 1 NACHT domain Ge1_WD40 PF16529.5 KEY74895.1 - 8.4e-10 38.1 18.7 0.0033 16.5 1.7 6.6 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY74895.1 - 3.2e-06 26.7 0.1 0.72 9.1 0.0 4.7 3 1 3 6 6 6 3 WD40-like domain Nup160 PF11715.8 KEY74895.1 - 6.4e-06 25.1 6.3 12 4.4 0.0 6.4 2 2 4 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEY74895.1 - 0.00094 17.8 6.0 0.078 11.5 0.1 4.0 1 1 4 5 5 5 3 Cytochrome D1 heme domain PUA_3 PF17785.1 KEY74895.1 - 0.0017 18.2 1.6 95 2.9 0.0 6.3 7 0 0 7 7 7 0 PUA-like domain VID27 PF08553.10 KEY74895.1 - 0.037 13.1 0.3 3.4 6.6 0.0 3.1 2 1 0 3 3 3 0 VID27 C-terminal WD40-like domain AAA_19 PF13245.6 KEY74895.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEY74895.1 - 0.13 12.0 1.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_12 PF01670.16 KEY74897.1 - 8e-54 182.9 3.0 9.6e-54 182.6 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_43 PF04616.14 KEY74898.1 - 8.6e-27 94.2 3.7 2.9e-21 76.1 0.5 2.7 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEY74898.1 - 1.3e-13 51.2 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain TPR_10 PF13374.6 KEY74899.1 - 4.7e-61 201.2 0.1 8.3e-12 44.6 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEY74899.1 - 2.2e-43 146.4 0.3 2.8e-14 53.2 0.0 5.9 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEY74899.1 - 7.8e-14 50.6 2.2 0.012 15.6 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74899.1 - 2.8e-11 42.9 4.4 0.023 15.3 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEY74899.1 - 5e-10 39.0 1.6 0.36 11.3 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEY74899.1 - 1.5e-09 38.4 0.0 0.11 13.1 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74899.1 - 1e-07 31.7 7.5 3.1e-06 26.8 3.3 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KEY74899.1 - 1.1e-07 32.2 1.2 0.2 12.2 0.0 5.5 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY74899.1 - 1.1e-07 31.3 0.0 0.82 9.6 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74899.1 - 1.6e-07 31.0 0.1 0.84 10.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74899.1 - 2.6e-07 30.2 0.1 1.7 8.9 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74899.1 - 2.2e-06 28.0 2.1 3.6 8.6 0.0 6.0 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KEY74899.1 - 0.002 18.0 0.0 20 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KEY74899.1 - 0.0054 17.0 0.3 5.1 7.4 0.0 2.9 1 1 1 3 3 3 1 Tetratrico peptide repeat PPR PF01535.20 KEY74899.1 - 0.06 13.6 0.0 1.1e+02 3.5 0.0 4.0 4 0 0 4 4 4 0 PPR repeat DMRT-like PF15791.5 KEY74899.1 - 0.064 13.7 0.4 0.56 10.6 0.1 2.4 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 PPR_1 PF12854.7 KEY74899.1 - 0.13 11.9 0.0 1.4e+02 2.3 0.0 3.7 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.6 KEY74899.1 - 2.4 9.0 6.1 1.4e+02 3.4 0.0 4.9 6 1 0 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.7 KEY74900.1 - 0.00076 19.3 1.2 0.0025 17.7 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEY74900.1 - 0.12 12.3 6.0 0.11 12.4 2.8 2.7 2 1 0 2 2 2 0 F-box domain adh_short PF00106.25 KEY74902.1 - 2.4e-24 85.9 0.0 3e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74902.1 - 8e-15 55.0 0.0 6.6e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74902.1 - 1.3e-11 44.7 0.1 2e-11 44.2 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY74902.1 - 1.7e-06 27.7 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEY74902.1 - 0.0064 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ank_4 PF13637.6 KEY74903.1 - 0.00032 21.2 0.1 0.0007 20.1 0.1 1.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEY74903.1 - 0.00075 20.0 0.0 0.0011 19.5 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEY74903.1 - 0.00079 19.7 0.1 0.0016 18.7 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Rad21_Rec8_N PF04825.13 KEY74905.1 - 3.1e-32 111.0 0.1 7.8e-32 109.7 0.0 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KEY74905.1 - 3.5e-07 29.4 0.0 8e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ANAPC1 PF12859.7 KEY74906.1 - 5.9 7.5 9.4 9.1 6.9 7.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Peptidase_S8 PF00082.22 KEY74910.1 - 3.8e-16 59.2 10.3 2e-09 37.1 5.3 2.1 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 KEY74910.1 - 6.3e-05 23.6 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPR_12 PF13424.6 KEY74911.1 - 3.3e-12 46.5 0.1 1.3e-07 31.8 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEY74911.1 - 1.9e-08 34.7 0.3 0.02 15.4 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEY74911.1 - 1.6e-07 30.9 0.1 0.00028 20.7 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEY74911.1 - 3.8e-05 24.2 0.3 2.2 9.3 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEY74911.1 - 0.00018 21.8 0.1 3.1 8.7 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEY74911.1 - 0.00051 20.0 3.2 0.58 10.4 0.3 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEY74911.1 - 0.00087 19.3 2.3 1 9.8 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEY74911.1 - 0.023 15.3 0.8 1.3 9.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY74911.1 - 0.07 12.5 0.0 1.6 8.0 0.0 1.9 1 1 1 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 KEY74911.1 - 0.09 12.9 0.1 17 5.7 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEY74911.1 - 0.2 11.9 0.3 8.8 6.6 0.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KEY74911.1 - 0.32 10.9 1.8 3.4 7.7 0.2 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Spc7 PF08317.11 KEY74912.1 - 0.015 14.2 10.3 0.02 13.8 10.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5129 PF17173.4 KEY74912.1 - 0.015 14.5 4.2 0.021 14.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) XkdW PF09636.10 KEY74912.1 - 0.026 14.6 1.6 0.14 12.2 0.6 2.2 1 1 0 1 1 1 0 XkdW protein Surfac_D-trimer PF09006.11 KEY74912.1 - 0.04 13.8 0.3 0.085 12.8 0.3 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF4407 PF14362.6 KEY74912.1 - 0.049 13.0 6.6 0.063 12.6 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KEY74912.1 - 0.24 11.5 6.7 0.28 11.3 1.5 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Atg14 PF10186.9 KEY74912.1 - 1.2 8.2 8.2 1.7 7.6 8.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NBP1 PF08537.10 KEY74912.1 - 2.2 7.6 8.3 3.1 7.1 8.3 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 UPF0242 PF06785.11 KEY74912.1 - 2.2 8.4 9.9 1.6 8.8 7.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KEY74912.1 - 2.8 8.0 13.7 4.1 7.5 13.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 KEY74912.1 - 4.6 6.7 12.2 6.9 6.2 12.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HAUS6_N PF14661.6 KEY74912.1 - 4.9 6.7 9.1 7.2 6.1 9.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ank_2 PF12796.7 KEY74913.1 - 2.2e-22 79.4 0.1 2.2e-08 34.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74913.1 - 1.3e-16 60.7 6.1 6.4e-07 29.8 0.0 6.3 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74913.1 - 2.5e-16 58.1 3.2 3.6e-05 23.8 0.0 7.8 7 1 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KEY74913.1 - 1e-14 54.4 1.9 3.1e-05 24.2 0.0 5.7 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KEY74913.1 - 7.2e-14 51.5 0.1 0.0081 16.6 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Pkinase PF00069.25 KEY74914.1 - 5.9e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY74914.1 - 4.8e-12 45.7 0.0 9.5e-12 44.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEY74914.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ALIX_LYPXL_bnd PF13949.6 KEY74914.1 - 0.061 12.6 0.9 0.12 11.7 0.3 1.7 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV APH PF01636.23 KEY74914.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arg_decarb_HB PF17810.1 KEY74914.1 - 0.14 12.4 0.0 0.74 10.1 0.0 2.2 1 1 0 1 1 1 0 Arginine decarboxylase helical bundle domain HeLo PF14479.6 KEY74915.1 - 5.5e-10 39.4 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Prion-inhibition and propagation KxDL PF10241.9 KEY74915.1 - 0.21 11.9 2.4 0.54 10.6 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Abhydrolase_2 PF02230.16 KEY74916.1 - 3.6e-28 98.8 0.0 4.8e-20 72.3 0.1 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KEY74916.1 - 5.2e-05 22.6 0.1 0.24 10.6 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEY74916.1 - 0.00085 18.9 0.1 0.006 16.1 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KEY74916.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KEY74916.1 - 0.016 15.8 0.0 0.03 14.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.11 KEY74916.1 - 0.057 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.13 KEY74916.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 KEY74917.1 - 1.6e-08 34.2 0.5 0.038 13.2 0.3 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KEY74917.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY74917.1 - 0.022 14.4 0.2 0.046 13.3 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEY74917.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEY74917.1 - 0.058 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY74917.1 - 0.081 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1013 PF06242.11 KEY74917.1 - 0.21 11.6 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Fungal_trans_2 PF11951.8 KEY74918.1 - 0.0011 17.8 0.0 0.0022 16.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA PF00004.29 KEY74919.1 - 9.7e-20 71.3 0.0 2.2e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 KEY74919.1 - 2.7e-19 69.4 0.3 5.2e-16 58.7 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74919.1 - 3.6e-10 39.8 0.2 2.6e-07 30.4 0.3 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74919.1 - 2.3e-07 30.9 1.6 3.9e-07 30.1 0.8 1.7 2 0 0 2 2 2 1 KR domain AAA_16 PF13191.6 KEY74919.1 - 0.00016 22.1 0.4 0.0047 17.3 0.2 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEY74919.1 - 0.0083 16.4 0.1 0.029 14.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KEY74919.1 - 0.009 16.0 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEY74919.1 - 0.04 14.5 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 KEY74919.1 - 0.064 12.9 0.2 0.49 10.0 0.0 2.5 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 KEY74919.1 - 0.098 12.8 0.5 0.29 11.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 KEY74919.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Arylsulfotran_2 PF14269.6 KEY74922.1 - 1.4e-57 195.4 0.2 1.9e-57 195.0 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEY74922.1 - 7.2e-13 48.2 0.1 6.5e-12 45.1 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KEY74922.1 - 0.029 14.3 1.0 20 5.3 0.0 4.1 4 1 1 5 5 5 0 PQQ enzyme repeat Sulfatase PF00884.23 KEY74923.1 - 3.9e-58 197.3 0.3 5.1e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEY74923.1 - 0.0014 18.3 1.2 0.5 9.9 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KEY74923.1 - 0.049 13.9 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 KEY74923.1 - 0.086 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Fungal_trans PF04082.18 KEY74924.1 - 2.8e-11 43.0 0.2 2.8e-11 43.0 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD-oxidase_C PF02913.19 KEY74925.1 - 8.4e-64 215.6 0.2 1.3e-63 215.0 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEY74925.1 - 2.5e-39 134.2 0.0 4.9e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aminotran_1_2 PF00155.21 KEY74926.1 - 1.8e-62 211.6 0.0 2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEY74926.1 - 0.0065 15.0 0.0 0.018 13.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEY74926.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.16 KEY74927.1 - 1e-43 149.7 32.2 2.5e-43 148.4 32.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY74927.1 - 9.2e-11 41.2 2.9 9.2e-11 41.2 2.9 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEY74927.1 - 4e-07 28.9 5.5 7.2e-07 28.0 5.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRAP PF15183.6 KEY74927.1 - 2.8 8.0 4.8 30 4.7 1.5 2.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family OATP PF03137.20 KEY74927.1 - 8.7 4.5 13.5 99 1.0 12.5 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KEY74928.1 - 1.6e-36 126.0 26.5 1.2e-35 123.0 24.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro2_C5 PF18565.1 KEY74930.1 - 4.4e-33 113.2 0.0 7.8e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KEY74930.1 - 1e-26 93.8 0.1 2.3e-26 92.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KEY74930.1 - 3.7e-20 71.6 0.0 8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 KEY74930.1 - 1.4e-19 70.6 0.1 6.9e-19 68.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KEY74930.1 - 6.1e-13 49.4 0.0 1.7e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 KEY74930.1 - 6.7e-05 23.1 0.1 0.00019 21.6 0.1 1.8 1 0 0 1 1 1 1 Invasin, domain 3 Big_1 PF02369.16 KEY74930.1 - 0.008 16.2 1.4 0.016 15.2 0.6 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) DUF4177 PF13783.6 KEY74932.1 - 0.4 11.0 1.2 1.6 9.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4177) p450 PF00067.22 KEY74933.1 - 0.00029 19.7 0.0 0.0004 19.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KEY74935.1 - 1.7e-44 152.1 2.5 2e-44 151.9 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY74935.1 - 4.5e-37 127.4 1.0 5.4e-37 127.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY74935.1 - 1.7e-06 28.1 0.4 2.6e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KEY74935.1 - 5.5e-05 23.1 0.1 0.0001 22.3 0.1 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.21 KEY74935.1 - 0.023 14.2 0.2 0.11 11.9 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KEY74935.1 - 0.059 13.3 0.4 0.086 12.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PfkB PF00294.24 KEY74937.1 - 7.4e-15 55.0 0.0 1e-14 54.6 0.0 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Transp_cyt_pur PF02133.15 KEY74938.1 - 2.4e-88 296.8 46.5 3e-88 296.5 46.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RSN1_7TM PF02714.15 KEY74939.1 - 1.6e-75 253.9 13.4 1.6e-75 253.9 13.4 1.9 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEY74939.1 - 3.9e-39 133.9 3.7 1e-38 132.5 3.7 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KEY74939.1 - 7.8e-23 80.5 0.1 1.5e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 KEY74939.1 - 1.4e-21 77.6 0.0 2.4e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3420 PF11900.8 KEY74939.1 - 0.19 11.9 1.4 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) Glyco_hydro_61 PF03443.14 KEY74940.1 - 2.7e-51 174.4 0.0 3.8e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY74940.1 - 3.1e-12 46.2 15.7 1e-11 44.6 15.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEY74940.1 - 0.41 10.9 2.5 1.1 9.6 2.5 1.7 1 0 0 1 1 1 0 Toxin 7 Sporozoite_P67 PF05642.11 KEY74940.1 - 2 6.4 4.6 2.6 6.0 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_31 PF01055.26 KEY74941.1 - 3.5e-146 487.8 3.8 4.5e-146 487.5 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KEY74941.1 - 2e-36 124.7 0.0 4.4e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KEY74941.1 - 2.2e-13 50.3 1.0 7.4e-13 48.6 1.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KEY74941.1 - 0.062 13.6 0.2 0.19 12.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KEY74942.1 - 1.9e-36 125.7 46.3 2e-29 102.6 38.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5310 PF17237.2 KEY74942.1 - 0.0091 15.9 0.7 0.034 14.0 0.7 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5310) DUF1230 PF06799.11 KEY74942.1 - 0.64 10.1 2.9 0.67 10.1 0.1 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 OATP PF03137.20 KEY74942.1 - 1.2 7.3 12.7 0.24 9.6 0.5 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TcpE PF12648.7 KEY74942.1 - 5.2 7.7 5.4 1.7 9.2 0.7 2.5 2 0 0 2 2 2 0 TcpE family Glyco_hydro_92 PF07971.12 KEY74943.1 - 2.2e-138 462.1 0.0 2.7e-138 461.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KEY74943.1 - 5.1e-53 180.4 1.8 7.4e-53 179.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Acetyltransf_1 PF00583.25 KEY74943.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.18 KEY74944.1 - 3.2e-08 32.9 0.0 5.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74944.1 - 3.1e-07 30.4 10.3 3.1e-07 30.4 10.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_CXXC_CXXC PF09706.10 KEY74944.1 - 0.13 12.6 1.3 3 8.1 0.0 2.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Polyketide_cyc2 PF10604.9 KEY74945.1 - 7.1e-08 32.8 2.0 1.3e-07 31.9 2.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RGM_C PF06534.13 KEY74945.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus G_glu_transpept PF01019.21 KEY74947.1 - 1.4e-162 542.1 0.0 1.6e-162 541.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Gln-synt_C PF00120.24 KEY74948.1 - 5.8e-41 140.6 0.0 7.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Tobravirus_2B PF05271.11 KEY74948.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Tobravirus 2B protein Glyco_hydro_6 PF01341.17 KEY74950.1 - 1.8e-06 27.9 0.0 2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Fungal_trans PF04082.18 KEY74951.1 - 2.6e-17 62.7 0.2 8.5e-17 61.1 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74951.1 - 1.8e-05 24.7 7.9 3.1e-05 24.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KEY74952.1 - 7.9e-91 305.3 0.0 1.3e-90 304.5 0.0 1.4 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KEY74952.1 - 3.4e-87 292.4 0.0 7.7e-87 291.3 0.0 1.6 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KEY74952.1 - 7.3e-66 221.7 0.1 1.3e-65 220.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEY74952.1 - 2.6e-37 127.7 0.0 7.3e-37 126.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KEY74952.1 - 2.9e-34 118.6 0.0 5.6e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KEY74952.1 - 8.6e-31 106.2 0.0 2.8e-29 101.4 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEY74952.1 - 7.2e-13 48.2 0.1 2.2e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEY74952.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KEY74952.1 - 4.7e-07 29.5 0.0 0.0056 16.5 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KEY74952.1 - 1.6e-05 24.5 0.1 3.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KEY74952.1 - 0.00039 20.1 0.0 0.00091 18.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KEY74952.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Ctr PF04145.15 KEY74954.1 - 2.3e-07 31.5 1.1 2.6e-07 31.4 1.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRR1 PF07985.12 KEY74956.1 - 1.6e-10 40.9 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 PTP_tm PF18861.1 KEY74957.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Macoilin PF09726.9 KEY74957.1 - 0.15 10.6 0.7 0.17 10.4 0.7 1.1 1 0 0 1 1 1 0 Macoilin family Gram_pos_anchor PF00746.21 KEY74957.1 - 0.33 10.9 0.1 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Alpha_GJ PF03229.13 KEY74957.1 - 4.6 7.8 7.5 0.21 12.1 1.9 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J Abhydrolase_2 PF02230.16 KEY74958.1 - 6.7e-05 22.8 0.0 0.00021 21.2 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KEY74958.1 - 8.1e-05 22.4 0.1 0.00011 22.0 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KEY74958.1 - 0.00062 19.3 0.8 0.0017 17.8 0.7 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KEY74958.1 - 0.0035 16.9 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DnaGprimase_HBD PF16730.5 KEY74959.1 - 0.077 13.1 0.9 0.34 11.0 0.4 2.3 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain zf-C3Hc3H PF13891.6 KEY74959.1 - 0.092 13.1 2.6 0.29 11.5 0.3 2.9 3 0 0 3 3 3 0 Potential DNA-binding domain PHD PF00628.29 KEY74960.1 - 1.5e-10 40.8 32.1 6e-08 32.5 12.4 3.6 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 KEY74960.1 - 0.015 15.5 0.3 0.015 15.5 0.3 3.5 4 0 0 4 4 4 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KEY74960.1 - 0.071 13.3 0.3 0.071 13.3 0.3 3.0 4 0 0 4 4 4 0 PHD-zinc-finger like domain GP70 PF17429.2 KEY74960.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Gene product 70 PHD_2 PF13831.6 KEY74960.1 - 0.15 11.6 6.7 1.1 8.9 4.2 3.1 2 0 0 2 2 2 0 PHD-finger Beta_helix PF13229.6 KEY74961.1 - 2.4e-10 40.5 17.5 2.5e-10 40.4 11.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region tRNA-synt_2c PF01411.19 KEY74961.1 - 2.1e-07 29.9 0.0 3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KEY74961.1 - 1.8e-05 24.8 0.5 3.1e-05 24.0 0.5 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Chondroitinas_B PF14592.6 KEY74961.1 - 2.3e-05 23.5 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Chondroitinase B Glyco_hydro_67M PF07488.12 KEY74962.1 - 7.7e-134 445.8 0.0 1.1e-133 445.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KEY74962.1 - 6.3e-80 267.9 0.2 9.8e-80 267.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KEY74962.1 - 2.2e-18 66.7 0.0 1.4e-15 57.6 0.0 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus DUF4838 PF16126.5 KEY74962.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Glyco_hydro_11 PF00457.17 KEY74963.1 - 2.1e-73 245.7 17.9 2.5e-73 245.5 17.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 LVIVD PF08309.11 KEY74965.1 - 7.9e-06 25.1 0.3 0.019 14.2 0.3 3.3 3 0 0 3 3 3 2 LVIVD repeat NmrA PF05368.13 KEY74966.1 - 9.8e-29 100.6 0.0 1.6e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY74966.1 - 1.1e-22 80.9 0.0 1.5e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HTH_psq PF05225.16 KEY74966.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain NAD_binding_4 PF07993.12 KEY74966.1 - 0.13 11.4 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Fungal_trans_2 PF11951.8 KEY74967.1 - 2e-11 43.4 3.7 4.3e-08 32.4 0.5 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Noelin-1 PF12308.8 KEY74967.1 - 0.1 12.6 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein adh_short PF00106.25 KEY74968.1 - 4.2e-42 143.8 0.1 5.4e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY74968.1 - 1.2e-24 87.1 0.3 1.6e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY74968.1 - 5.3e-15 55.8 0.5 9.4e-15 55.0 0.3 1.4 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KEY74968.1 - 2.8e-06 26.9 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KEY74968.1 - 0.00017 21.5 0.3 0.00025 21.0 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY74968.1 - 0.0012 18.3 0.5 0.0053 16.3 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Trypsin PF00089.26 KEY74969.1 - 3.5e-68 229.7 7.2 3.9e-68 229.6 7.2 1.0 1 0 0 1 1 1 1 Trypsin Toxin_4 PF00706.17 KEY74969.1 - 0.02 15.3 0.1 0.053 14.0 0.1 1.8 1 0 0 1 1 1 0 Anenome neurotoxin DNA_binding_1 PF01035.20 KEY74969.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain TMCO5 PF14992.6 KEY74970.1 - 0.7 9.4 2.9 0.9 9.1 2.9 1.1 1 0 0 1 1 1 0 TMCO5 family adh_short_C2 PF13561.6 KEY74972.1 - 8.8e-58 195.6 0.1 1.1e-57 195.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEY74972.1 - 1.9e-47 161.2 0.1 2.6e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEY74972.1 - 2.1e-13 50.6 0.0 4.8e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 KR domain HATPase_c PF02518.26 KEY74972.1 - 0.0085 16.6 0.2 0.051 14.1 0.1 2.3 1 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_3 PF13738.6 KEY74973.1 - 2e-16 60.2 0.0 1.1e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY74973.1 - 4.6e-13 48.4 0.0 7.5e-10 37.8 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEY74973.1 - 3.3e-11 42.9 0.0 3.3e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEY74973.1 - 4.2e-10 39.3 0.0 1.8e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEY74973.1 - 2e-05 24.7 0.0 6.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEY74973.1 - 0.00056 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KEY74973.1 - 0.043 14.4 0.4 11 6.7 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY74973.1 - 0.17 11.9 0.0 2.4 8.1 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KEY74974.1 - 1.6e-34 119.4 22.1 1.4e-33 116.3 24.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2649 PF10854.8 KEY74974.1 - 0.027 14.8 0.4 0.11 12.8 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) TPP_enzyme_N PF02776.18 KEY74975.1 - 1.1e-38 132.6 0.0 2e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEY74975.1 - 2.3e-13 50.2 0.0 4.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEY74975.1 - 5.2e-11 42.4 0.0 6.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AP4E_app_platf PF14807.6 KEY74975.1 - 0.057 13.8 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Aldedh PF00171.22 KEY74976.1 - 9.1e-132 439.8 0.0 1.1e-131 439.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEY74976.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Semialdhyde_dh PF01118.24 KEY74976.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UbiD PF01977.16 KEY74977.1 - 5.9e-114 381.1 0.0 6.9e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Fungal_trans PF04082.18 KEY74978.1 - 9.2e-09 34.7 0.1 1.9e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PAP1 PF08601.10 KEY74978.1 - 6.3 6.4 7.8 9.9 5.8 7.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 MFS_1 PF07690.16 KEY74979.1 - 1.1e-35 123.2 45.9 1.1e-35 123.2 45.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KEY74979.1 - 0.0022 16.3 6.4 0.29 9.4 7.9 2.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF202 PF02656.15 KEY74979.1 - 3.5 8.1 9.6 17 6.0 2.0 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 KEY74981.1 - 1.1e-20 73.9 63.6 2.1e-18 66.4 46.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RTX PF02382.15 KEY74982.1 - 9.8e-05 22.2 2.1 0.00014 21.6 2.1 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein Atrophin-1 PF03154.15 KEY74982.1 - 0.015 13.6 0.1 0.023 13.0 0.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family TcdA_TcdB_pore PF12920.7 KEY74982.1 - 0.084 11.1 1.9 0.092 11.0 1.9 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Mobilization_B PF17511.2 KEY74982.1 - 0.23 11.8 3.6 0.33 11.3 3.6 1.2 1 0 0 1 1 1 0 Mobilization protein B DUF543 PF04418.12 KEY74982.1 - 0.77 9.8 3.5 1.9 8.6 3.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF543) DUF4337 PF14235.6 KEY74982.1 - 0.97 9.5 8.1 0.12 12.5 4.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HABP4_PAI-RBP1 PF04774.15 KEY74982.1 - 1.1 10.1 12.1 0.77 10.6 0.7 2.2 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family CRA PF06589.11 KEY74982.1 - 8.6 6.5 7.0 0.83 9.8 0.5 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Fungal_trans PF04082.18 KEY74983.1 - 6.9e-16 58.1 0.3 2.7e-15 56.1 0.2 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74983.1 - 3.2e-05 24.0 13.0 3.2e-05 24.0 13.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_N PF13396.6 KEY74984.1 - 1.1e-09 38.0 7.4 1.1e-09 38.0 7.4 2.1 3 0 0 3 3 3 1 Phospholipase_D-nuclease N-terminal ATP-synt_J PF04911.12 KEY74984.1 - 0.26 10.9 0.9 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase j chain AAA_16 PF13191.6 KEY74985.1 - 2e-08 34.8 3.6 8.5e-08 32.8 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain TPR_12 PF13424.6 KEY74985.1 - 7.3e-06 26.2 16.2 0.39 11.0 0.0 9.9 12 1 0 12 12 12 1 Tetratricopeptide repeat AAA_22 PF13401.6 KEY74985.1 - 2.6e-05 24.5 0.8 0.00028 21.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KEY74985.1 - 0.0017 18.3 0.0 0.011 15.6 0.0 2.6 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.6 KEY74985.1 - 0.0024 18.5 0.0 3.2 8.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEY74985.1 - 0.058 13.3 3.4 28 4.8 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Torsin PF06309.11 KEY74985.1 - 0.074 13.2 0.0 0.4 10.8 0.0 2.3 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 KEY74985.1 - 0.1 13.1 0.3 0.51 10.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KEY74985.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.9 1 0 0 1 1 1 0 RNA helicase TPR_2 PF07719.17 KEY74985.1 - 3 8.2 5.2 29 5.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_35 PF01301.19 KEY74986.1 - 2.8e-88 296.6 0.6 3.7e-88 296.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KEY74986.1 - 1.8e-57 192.9 0.3 9.3e-31 106.8 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KEY74986.1 - 3.8e-56 189.8 1.7 5.8e-56 189.2 1.7 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KEY74986.1 - 3.6e-19 68.1 0.0 9.4e-19 66.8 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KEY74986.1 - 0.00075 18.9 0.0 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase DUF4115 PF13464.6 KEY74986.1 - 0.049 13.8 0.1 0.22 11.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) Sugar_tr PF00083.24 KEY74987.1 - 1.1e-71 242.1 25.7 1.2e-71 241.9 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY74987.1 - 1.3e-08 34.2 48.8 5.1e-08 32.2 40.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY74987.1 - 2.8e-05 22.9 15.5 0.0006 18.5 4.5 2.7 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KEY74987.1 - 0.00075 18.5 6.0 0.00075 18.5 6.0 2.3 2 0 0 2 2 2 1 MFS_1 like family Snapin_Pallidin PF14712.6 KEY74988.1 - 0.045 14.2 5.2 0.61 10.5 4.4 2.9 2 0 0 2 2 2 0 Snapin/Pallidin Goodbye PF17109.5 KEY74988.1 - 0.21 12.0 5.6 0.82 10.1 0.0 4.0 4 2 1 5 5 5 0 fungal STAND N-terminal Goodbye domain Hrs_helical PF12210.8 KEY74988.1 - 0.35 11.4 7.9 0.76 10.4 0.1 3.7 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CorA PF01544.18 KEY74988.1 - 1.8 7.8 4.9 21 4.3 4.9 2.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3425 PF11905.8 KEY74989.1 - 1.2e-20 73.7 0.0 2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KEY74989.1 - 0.00076 19.5 10.5 0.0012 18.9 10.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KEY74989.1 - 0.0086 16.6 7.1 0.015 15.8 7.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HOOK PF05622.12 KEY74989.1 - 0.022 12.9 0.0 0.029 12.5 0.0 1.0 1 0 0 1 1 1 0 HOOK protein bZIP_2 PF07716.15 KEY74989.1 - 0.088 12.9 13.6 0.14 12.2 13.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper TSC22 PF01166.18 KEY74989.1 - 0.2 12.0 0.2 0.43 10.9 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 KEY74989.1 - 0.95 9.3 4.6 0.78 9.5 1.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.25 KEY74990.1 - 2.8e-05 24.3 0.3 5e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY74990.1 - 6e-05 23.0 0.1 0.00014 21.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEY74990.1 - 0.00019 21.8 0.4 0.0018 18.7 0.3 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY74990.1 - 0.0059 16.7 0.5 0.077 13.1 0.0 2.8 2 1 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEY74990.1 - 0.016 15.2 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein DUF4238 PF14022.6 KEY74991.1 - 7.9e-42 143.6 0.0 9.1e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Ank_2 PF12796.7 KEY74994.1 - 3.6e-68 226.2 12.0 5.8e-14 52.4 0.1 8.7 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY74994.1 - 4.1e-55 183.5 9.2 2.8e-10 40.5 0.1 11.6 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY74994.1 - 5.2e-51 164.7 12.4 0.00033 20.9 0.0 14.5 15 0 0 15 15 14 10 Ankyrin repeat Ank PF00023.30 KEY74994.1 - 4.9e-50 165.9 36.9 5.6e-05 23.4 0.0 15.2 14 1 1 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 KEY74994.1 - 6e-43 144.4 22.9 1.8e-07 31.3 0.0 11.3 7 3 5 12 12 11 10 Ankyrin repeats (many copies) NACHT PF05729.12 KEY74994.1 - 1.1e-12 48.2 0.2 2.9e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEY74994.1 - 2.1e-07 31.5 1.4 7.2e-07 29.7 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEY74994.1 - 1.2e-06 28.8 0.1 5.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KEY74994.1 - 0.0068 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KEY74994.1 - 0.039 14.4 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KEY74994.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 NTPase Fungal_trans PF04082.18 KEY74996.1 - 2.3e-26 92.4 0.2 3.4e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY74996.1 - 4.2e-08 33.2 10.8 9.4e-08 32.1 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprB PF13573.6 KEY74996.1 - 1.8 8.4 4.3 3.7 7.4 4.3 1.5 1 0 0 1 1 1 0 SprB repeat Mannitol_dh_C PF08125.13 KEY74997.1 - 4.7e-74 249.0 0.0 6.6e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KEY74997.1 - 3.3e-46 157.2 0.0 5.8e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Exotox-A_bind PF09101.10 KEY74997.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A binding Rieske PF00355.26 KEY74998.1 - 7.5e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Sar8_2 PF03058.14 KEY74998.1 - 0.085 13.4 0.8 0.25 11.9 0.8 1.7 1 0 0 1 1 1 0 Sar8.2 family YlqD PF11068.8 KEY74998.1 - 0.81 10.1 4.8 1.2 9.5 4.8 1.2 1 0 0 1 1 1 0 YlqD protein Ring_hydroxyl_A PF00848.19 KEY74999.1 - 6.7e-25 88.3 2.1 2.7e-15 56.9 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Zn_clus PF00172.18 KEY75000.1 - 1.5e-05 25.0 13.7 2.9e-05 24.1 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCR PF12273.8 KEY75000.1 - 0.042 14.5 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Phage_holin_7_1 PF16081.5 KEY75000.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DAO PF01266.24 KEY75001.1 - 2.7e-36 125.9 0.3 3.4e-36 125.6 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY75001.1 - 5.4e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY75001.1 - 0.00023 20.5 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY75001.1 - 0.005 16.0 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEY75001.1 - 0.0066 17.0 0.0 0.025 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KEY75001.1 - 0.027 13.9 0.0 0.17 11.4 0.0 2.2 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KEY75001.1 - 0.045 13.8 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KEY75001.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KEY75001.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.13 KEY75002.1 - 3.3e-13 50.0 0.2 3.9e-12 46.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEY75002.1 - 2.1e-09 37.2 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KEY75002.1 - 8.9e-08 31.5 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KEY75002.1 - 2.5e-07 29.9 0.0 4.9e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KEY75002.1 - 7.6e-06 25.4 0.1 0.013 14.8 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KEY75002.1 - 8.4e-05 22.3 0.1 0.00061 19.5 0.0 2.0 2 0 0 2 2 2 1 Putative esterase COesterase PF00135.28 KEY75002.1 - 0.00046 19.2 0.0 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KEY75002.1 - 0.00083 20.0 1.8 0.0013 19.4 1.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KEY75002.1 - 0.002 17.7 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Say1_Mug180 PF10340.9 KEY75002.1 - 0.027 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Transferase PF02458.15 KEY75003.1 - 0.00016 20.5 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 Transferase family DAO PF01266.24 KEY75004.1 - 8e-25 88.2 1.0 9.3e-25 87.9 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY75004.1 - 0.00092 18.5 0.1 0.0018 17.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY75004.1 - 0.0083 16.7 1.2 0.019 15.5 1.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KEY75005.1 - 8e-58 195.9 0.0 1.1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Adenine_deam_C PF13382.6 KEY75005.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain GDP_Man_Dehyd PF16363.5 KEY75007.1 - 9.5e-68 229.0 0.0 1.3e-67 228.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEY75007.1 - 1.4e-62 211.3 0.0 1.7e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEY75007.1 - 1.3e-22 80.1 0.0 1.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEY75007.1 - 1.9e-17 63.4 0.0 2.1e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEY75007.1 - 5.8e-14 51.9 0.0 7.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEY75007.1 - 2.2e-11 43.4 0.0 9.9e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEY75007.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY75007.1 - 6.1e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KEY75007.1 - 8.7e-05 22.1 0.0 0.00022 20.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KEY75007.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEY75007.1 - 0.054 13.7 0.1 0.087 13.1 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 KEY75007.1 - 0.14 11.7 0.0 0.45 10.0 0.0 1.8 1 1 0 1 1 1 0 NmrA-like family Sulfotransfer_4 PF17784.1 KEY75009.1 - 2e-62 210.9 0.0 2.6e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY75009.1 - 3.9e-06 27.4 0.1 0.00054 20.4 0.0 2.6 1 1 2 3 3 3 2 Sulfotransferase family PG_binding_2 PF08823.11 KEY75009.1 - 0.03 14.6 0.5 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Ysc84 PF04366.12 KEY75010.1 - 1.8e-46 157.1 0.1 2.8e-46 156.4 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator adh_short PF00106.25 KEY75011.1 - 2.2e-20 73.0 0.0 2.9e-14 53.0 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75011.1 - 3.9e-07 29.9 0.0 0.00017 21.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY75011.1 - 0.00085 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KEY75012.1 - 7e-05 21.8 1.0 0.00018 20.5 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain TMEM52 PF14979.6 KEY75012.1 - 0.085 12.8 0.5 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 Transmembrane 52 HD PF01966.22 KEY75014.1 - 8e-10 39.0 0.2 1.2e-09 38.5 0.2 1.2 1 0 0 1 1 1 1 HD domain Methyltransf_22 PF13383.6 KEY75015.1 - 2.6e-10 40.3 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KEY75015.1 - 2.3e-07 31.0 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain MFS_5 PF05631.14 KEY75016.1 - 2.3e-56 191.2 8.1 5.5e-56 190.0 8.1 1.5 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KEY75016.1 - 8.4e-14 51.3 34.3 1.4e-13 50.5 34.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 KEY75017.1 - 3.7e-28 99.0 0.0 5.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) F-box-like PF12937.7 KEY75020.1 - 2.9e-07 30.3 0.9 2e-06 27.6 0.0 2.8 2 1 0 2 2 2 1 F-box-like PRANC PF09372.10 KEY75020.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 PRANC domain Peroxidase_2 PF01328.17 KEY75021.1 - 3.3e-28 99.5 0.0 4.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 D-ser_dehydrat PF14031.6 KEY75022.1 - 8.9e-21 74.4 0.1 2e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KEY75022.1 - 2.1e-15 57.0 0.0 3.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4470 PF14737.6 KEY75023.1 - 6.6e-30 103.2 0.0 1.5e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) PPR_2 PF13041.6 KEY75023.1 - 0.055 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 KEY75023.1 - 0.16 12.3 0.2 0.85 10.0 0.1 2.3 2 0 0 2 2 2 0 PPR repeat PhyH PF05721.13 KEY75024.1 - 6.8e-10 39.6 0.0 9.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KEY75024.1 - 1.2e-06 27.6 0.0 0.018 13.8 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 KEY75025.1 - 7.3e-74 249.3 29.5 8.7e-74 249.0 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY75025.1 - 6.1e-21 74.7 27.7 6.1e-21 74.7 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEY75025.1 - 0.004 16.5 11.5 0.004 16.5 11.5 2.7 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ERGIC_N PF13850.6 KEY75025.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.8 4 1 1 5 5 5 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1772 PF08592.11 KEY75026.1 - 0.33 11.3 5.2 0.89 9.9 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Citrate_synt PF00285.21 KEY75028.1 - 1.5e-88 297.3 0.0 1.8e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MFS_1 PF07690.16 KEY75030.1 - 4.7e-47 160.6 20.9 1e-40 139.8 12.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEY75030.1 - 1.7e-05 23.5 2.5 3.1e-05 22.6 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KEY75030.1 - 0.00015 20.3 0.7 0.00027 19.5 0.7 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF3267 PF11667.8 KEY75030.1 - 0.0013 19.0 1.3 0.0013 19.0 1.3 2.5 3 0 0 3 3 3 1 Putative zincin peptidase OATP PF03137.20 KEY75030.1 - 0.0041 15.5 2.5 0.014 13.7 0.3 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family SPC12 PF06645.13 KEY75030.1 - 0.44 10.7 0.1 0.44 10.7 0.1 3.7 4 1 1 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Pectate_lyase PF03211.13 KEY75031.1 - 5.5e-76 254.6 7.1 8.1e-76 254.1 7.1 1.2 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 KEY75031.1 - 6e-11 42.1 10.0 6e-11 42.1 10.0 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Chlam_PMP PF02415.17 KEY75031.1 - 0.62 10.7 9.1 0.34 11.5 2.5 3.3 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Zn_clus PF00172.18 KEY75034.1 - 0.00017 21.7 7.1 0.00036 20.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 KEY75034.1 - 0.14 12.8 2.3 0.25 12.0 2.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M28 PF04389.17 KEY75036.1 - 6e-26 91.4 0.0 1.3e-25 90.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEY75036.1 - 4.8e-06 26.4 0.2 4.3e-05 23.3 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1996 PF09362.10 KEY75037.1 - 1.4e-71 241.3 2.9 1.7e-71 241.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.25 KEY75039.1 - 5.2e-21 75.0 0.0 2.9e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75039.1 - 4.4e-13 49.3 0.0 5.7e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY75039.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 KEY75040.1 - 0.00013 21.9 0.0 0.00018 21.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEY75040.1 - 0.001 18.3 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KEY75040.1 - 0.0051 16.3 0.0 0.0079 15.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KEY75040.1 - 0.0097 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KEY75040.1 - 0.053 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEY75040.1 - 0.058 13.7 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEY75040.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 KEY75041.1 - 1e-05 25.6 8.6 1.9e-05 24.7 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEY75042.1 - 8.7e-68 229.1 0.0 1.1e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KEY75043.1 - 4.1e-18 65.4 0.2 5.6e-18 64.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 KEY75044.1 - 2e-153 510.3 5.4 1.7e-68 231.5 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEY75044.1 - 5.3e-60 202.0 0.1 7.1e-32 110.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KEY75044.1 - 0.00098 18.8 0.6 1.8 8.9 0.1 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KEY75044.1 - 0.005 15.7 0.0 0.58 8.9 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KEY75044.1 - 0.012 15.6 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain ANAPC1 PF12859.7 KEY75044.1 - 0.76 10.3 5.2 0.15 12.6 0.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 NACHT PF05729.12 KEY75046.1 - 3.1e-18 66.2 0.0 5.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KEY75046.1 - 3.2e-07 31.0 0.1 7.1e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 KEY75046.1 - 3.1e-06 26.6 0.0 5.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KEY75046.1 - 0.0032 17.9 0.0 0.0065 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEY75046.1 - 0.0091 16.0 0.2 0.039 14.0 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEY75046.1 - 0.016 15.6 0.1 0.074 13.4 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEY75046.1 - 0.028 14.7 0.6 0.14 12.5 0.1 2.4 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KEY75046.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEY75046.1 - 0.15 11.9 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KEY75046.1 - 0.19 12.2 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NKWYS PF10364.9 KEY75046.1 - 0.21 11.7 1.0 0.39 10.8 1.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein HET PF06985.11 KEY75047.1 - 2.1e-29 102.8 1.2 3.7e-29 102.0 1.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KEY75048.1 - 7.2e-119 384.3 6.5 1.7e-09 38.1 0.0 13.0 13 0 0 13 13 13 12 WD domain, G-beta repeat NACHT_N PF17100.5 KEY75048.1 - 7.2e-87 290.9 1.1 7.2e-87 290.9 1.1 2.4 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KEY75048.1 - 6.2e-47 157.8 0.0 0.015 15.6 0.0 12.5 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY75048.1 - 1.2e-22 80.6 1.2 2.8e-22 79.4 0.1 2.2 3 0 0 3 3 3 1 NACHT domain Ge1_WD40 PF16529.5 KEY75048.1 - 2.5e-20 72.7 11.5 1.9 7.4 0.0 12.0 1 1 10 12 12 12 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KEY75048.1 - 1.5e-08 34.5 8.6 0.0018 17.9 0.3 4.8 1 1 3 4 4 4 4 PQQ-like domain Cytochrom_D1 PF02239.16 KEY75048.1 - 0.00077 18.1 0.1 14 4.0 0.0 4.6 2 1 2 6 6 6 1 Cytochrome D1 heme domain AAA_16 PF13191.6 KEY75048.1 - 0.0024 18.3 0.0 0.012 15.9 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain TruB_C PF09142.11 KEY75048.1 - 0.4 10.5 22.5 62 3.5 0.1 8.4 10 0 0 10 10 10 0 tRNA Pseudouridine synthase II, C terminal A1_Propeptide PF07966.12 KEY75048.1 - 1.5 8.7 5.0 6.4 6.8 0.0 4.4 7 0 0 7 7 7 0 A1 Propeptide WSC PF01822.19 KEY75051.1 - 3.7e-10 39.8 4.7 1.2e-09 38.2 4.7 2.0 1 0 0 1 1 1 1 WSC domain RPE65 PF03055.15 KEY75052.1 - 6.6e-124 414.6 0.0 7.5e-124 414.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_3_C PF01915.22 KEY75054.1 - 2.9e-49 167.8 0.1 4.3e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEY75054.1 - 3.4e-33 115.4 0.0 1.4e-32 113.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEY75054.1 - 8.9e-25 86.6 0.0 1.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Bac_rhodopsin PF01036.18 KEY75055.1 - 8.6e-55 185.7 12.6 1.2e-54 185.3 12.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 KEY75055.1 - 1 9.0 9.4 2 8.1 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 KEY75055.1 - 7.7 6.6 7.4 17 5.5 4.4 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Meth_synt_2 PF01717.18 KEY75056.1 - 2.9e-17 62.9 0.0 5.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEY75056.1 - 2.1e-05 24.2 0.0 0.0018 17.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.25 KEY75057.1 - 1e-25 90.3 0.0 1.3e-21 77.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75057.1 - 8.4e-14 51.7 0.1 7.3e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY75057.1 - 0.00013 21.9 0.4 0.00033 20.6 0.4 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY75057.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_61 PF03443.14 KEY75058.1 - 2.1e-55 187.9 0.0 2.8e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY75058.1 - 5.1e-09 35.9 12.0 5.1e-09 35.9 12.0 3.4 4 0 0 4 4 4 1 Fungal cellulose binding domain RseC_MucC PF04246.12 KEY75058.1 - 3.5 7.6 0.0 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TB2_DP1_HVA22 PF03134.19 KEY75059.1 - 9.6e-27 92.7 7.2 1.5e-26 92.2 7.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KEY75060.1 - 3.5e-82 274.0 0.0 6e-82 273.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Ndc1_Nup PF09531.10 KEY75060.1 - 0.67 8.6 6.5 0.88 8.2 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 KEY75060.1 - 2.7 7.9 9.3 3.4 7.6 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BPL_N PF09825.9 KEY75061.1 - 3.2e-139 464.2 0.0 3.8e-139 464.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KEY75061.1 - 3.4e-13 49.7 0.0 5.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pam16 PF03656.13 KEY75062.1 - 3.6e-31 107.8 0.4 4.4e-31 107.5 0.4 1.0 1 0 0 1 1 1 1 Pam16 Arm PF00514.23 KEY75063.1 - 0.049 13.7 0.9 6.2 7.0 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KEY75063.1 - 0.068 13.5 1.1 16 6.1 0.1 3.9 2 0 0 2 2 2 0 HEAT repeat Atx10homo_assoc PF09759.9 KEY75063.1 - 0.19 11.8 0.0 17 5.5 0.0 3.4 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Ribosomal_L13e PF01294.18 KEY75064.1 - 3.9e-72 241.9 2.1 5.6e-72 241.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Na_H_Exchanger PF00999.21 KEY75064.1 - 3.1e-40 138.2 19.1 4.1e-40 137.7 19.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KEY75064.1 - 0.021 14.9 1.2 0.054 13.6 0.1 2.3 2 0 0 2 2 2 0 YrhC-like protein DUF3382 PF11862.8 KEY75064.1 - 1.1 9.6 5.1 0.4 11.0 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DAO PF01266.24 KEY75065.1 - 2.9e-35 122.5 0.4 3.9e-35 122.1 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Acetyltransf_10 PF13673.7 KEY75065.1 - 6.1e-07 29.4 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY75065.1 - 7.7e-07 29.4 0.0 2.3e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEY75065.1 - 1.2e-06 28.8 0.0 4.5e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_8 PF13450.6 KEY75065.1 - 0.0002 21.5 1.7 0.00043 20.4 1.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEY75065.1 - 0.00085 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY75065.1 - 0.0019 18.7 0.4 0.012 16.2 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_CG PF14542.6 KEY75065.1 - 0.0057 16.8 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase NAD_binding_9 PF13454.6 KEY75065.1 - 0.09 12.8 0.7 0.29 11.1 0.4 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KEY75065.1 - 0.17 12.0 0.1 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AA_permease_2 PF13520.6 KEY75066.1 - 1.2e-43 149.6 45.0 1.5e-43 149.2 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEY75066.1 - 2.6e-12 46.1 38.1 3.5e-12 45.7 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease 6PF2K PF01591.18 KEY75067.1 - 0.077 12.3 0.0 9.5 5.5 0.0 2.6 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Acetyltransf_7 PF13508.7 KEY75068.1 - 1.2e-05 25.6 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEY75068.1 - 0.00065 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEY75068.1 - 0.0014 18.9 0.0 0.0039 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEY75068.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain COX14 PF14880.6 KEY75069.1 - 1.9e-18 66.0 0.2 1.9e-18 66.0 0.2 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.11 KEY75069.1 - 0.06 12.9 0.3 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF3403 PF11883.8 KEY75070.1 - 0.025 14.7 0.7 0.096 12.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) DAHP_synth_1 PF00793.20 KEY75071.1 - 5.6e-100 333.7 0.1 6.4e-100 333.5 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family YIEGIA PF14045.6 KEY75071.1 - 0.028 13.3 0.1 0.049 12.5 0.1 1.3 1 0 0 1 1 1 0 YIEGIA protein TPR_21 PF09976.9 KEY75072.1 - 0.037 13.8 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Ribosomal_L50 PF10501.9 KEY75073.1 - 2.8e-14 53.2 0.0 4.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Methyltransf_2 PF00891.18 KEY75074.1 - 1.4e-16 60.4 0.0 3.1e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain HTH_11 PF08279.12 KEY75074.1 - 0.0021 17.9 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 KEY75074.1 - 0.0028 17.2 0.1 0.0053 16.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Methyltransf_23 PF13489.6 KEY75075.1 - 6e-20 71.7 0.0 9.6e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY75075.1 - 1.8e-11 44.6 0.0 3.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY75075.1 - 1.8e-10 40.8 0.0 3.8e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY75075.1 - 3.1e-09 37.4 0.0 5.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY75075.1 - 9.2e-07 29.5 0.0 6e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEY75075.1 - 4.5e-05 23.0 0.0 9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KEY75075.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEY75075.1 - 0.0043 17.2 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0146 PF03686.13 KEY75075.1 - 0.042 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.18 KEY75075.1 - 0.076 12.3 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KEY75075.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEY75075.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_S8 PF00082.22 KEY75077.1 - 6.9e-33 114.2 11.0 1.8e-32 112.8 11.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEY75077.1 - 5.8e-10 39.7 0.1 2.8e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 HET PF06985.11 KEY75078.1 - 5.3e-11 43.1 7.3 1.6e-08 35.0 3.4 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Chromate_transp PF02417.15 KEY75079.1 - 2.9e-58 196.5 34.0 2.8e-34 118.5 11.5 2.4 3 0 0 3 3 3 2 Chromate transporter Pex24p PF06398.11 KEY75081.1 - 5.5e-96 321.7 2.6 5.5e-96 321.7 2.6 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Succ_DH_flav_C PF02910.20 KEY75082.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Vma12 PF11712.8 KEY75082.1 - 8.7 6.4 7.9 89 3.1 7.9 2.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ank_2 PF12796.7 KEY75084.1 - 4.5e-47 158.5 3.6 3.6e-13 49.9 0.1 4.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY75084.1 - 1.3e-28 99.0 0.3 7.4e-06 26.4 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY75084.1 - 1e-27 93.1 0.0 0.0011 19.3 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KEY75084.1 - 2.4e-25 88.3 2.0 5.7e-07 29.7 0.0 5.7 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KEY75084.1 - 9.9e-25 85.9 0.4 0.00092 19.6 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Prok-E2_E PF14462.6 KEY75084.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E FAD_binding_2 PF00890.24 KEY75085.1 - 6.5e-60 203.4 2.5 7.7e-60 203.1 2.5 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY75085.1 - 9.2e-12 45.2 0.8 1.3e-11 44.7 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEY75085.1 - 4.5e-08 33.2 0.8 1.2e-07 31.8 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEY75085.1 - 1.5e-07 31.1 2.9 3.3e-07 30.0 2.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEY75085.1 - 1.2e-05 24.8 2.9 6.1e-05 22.4 1.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEY75085.1 - 2.5e-05 23.7 0.8 4e-05 23.0 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KEY75085.1 - 3.4e-05 23.1 1.7 0.00033 19.9 0.6 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEY75085.1 - 0.00078 18.3 4.8 0.00087 18.1 1.0 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KEY75085.1 - 0.0013 18.1 0.2 0.0026 17.1 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEY75085.1 - 0.0015 17.9 0.0 0.049 12.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEY75085.1 - 0.0019 18.7 0.1 0.01 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEY75085.1 - 0.015 14.5 0.3 0.04 13.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KEY75085.1 - 0.033 13.3 0.4 0.053 12.6 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 KEY75085.1 - 0.12 11.1 0.4 0.18 10.5 0.4 1.2 1 0 0 1 1 1 0 MCRA family Ank_2 PF12796.7 KEY75086.1 - 2.2e-10 41.0 0.0 0.00018 22.0 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEY75086.1 - 7.4e-07 29.0 0.0 0.75 10.6 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KEY75086.1 - 0.00057 20.4 0.1 0.022 15.3 0.0 3.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Clr5 PF14420.6 KEY75086.1 - 0.0011 19.2 0.2 0.0042 17.3 0.2 2.0 1 1 0 1 1 1 1 Clr5 domain MAGE PF01454.19 KEY75086.1 - 0.087 12.5 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 MAGE family Ank_3 PF13606.6 KEY75087.1 - 4.4e-17 60.4 0.5 0.00084 19.6 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KEY75087.1 - 1.6e-16 60.6 0.0 4.1e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEY75087.1 - 5.9e-15 54.9 4.2 1.7e-05 25.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KEY75087.1 - 7.3e-13 48.5 3.2 0.00024 21.3 0.1 3.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEY75087.1 - 1.7e-11 44.4 0.1 5.3e-08 33.2 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Cu_amine_oxid PF01179.20 KEY75088.1 - 2.1e-113 379.4 0.7 2.5e-113 379.1 0.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KEY75088.1 - 3.9e-09 36.1 0.0 2.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KEY75088.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain adh_short PF00106.25 KEY75089.1 - 1.9e-18 66.6 0.0 2.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75089.1 - 1.1e-17 64.4 0.0 1.7e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KEY75089.1 - 0.00028 20.9 0.0 0.00052 20.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEY75089.1 - 0.0011 18.9 0.2 0.0022 17.9 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEY75089.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KEY75091.1 - 5e-72 242.8 0.0 7.2e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KEY75091.1 - 0.031 12.9 0.1 3 6.4 0.1 2.3 2 0 0 2 2 2 0 Condensation domain AMP-binding_C PF13193.6 KEY75091.1 - 0.14 13.2 0.0 0.36 11.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain p450 PF00067.22 KEY75092.1 - 3.3e-61 207.5 0.0 4.3e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMRP1 PF15181.6 KEY75092.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Pribosyltran PF00156.27 KEY75094.1 - 3.5e-08 33.1 0.0 4.9e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF3669 PF12417.8 KEY75095.1 - 0.00035 20.7 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Oxidored-like PF09791.9 KEY75096.1 - 2e-24 85.0 4.3 2e-24 85.0 4.3 1.7 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Epimerase_2 PF02350.19 KEY75097.1 - 0.014 14.2 0.1 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DPM3 PF08285.11 KEY75098.1 - 1.1e-35 121.7 0.1 1.2e-35 121.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) p450 PF00067.22 KEY75099.1 - 6.7e-51 173.5 0.0 8.4e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCR1_C PF12550.8 KEY75100.1 - 1.7e-17 63.5 0.0 3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4719 PF15843.5 KEY75100.1 - 0.15 12.2 1.1 0.26 11.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Dicty_REP PF05086.12 KEY75101.1 - 0.56 8.1 3.0 0.7 7.8 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Baculo_PEP_C PF04513.12 KEY75104.1 - 0.0059 16.6 4.4 0.056 13.5 0.3 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KEY75104.1 - 0.046 14.0 2.2 2.4 8.5 0.6 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2884 PF11101.8 KEY75104.1 - 0.093 12.2 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Cauli_VI PF01693.16 KEY75105.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin Sugar_tr PF00083.24 KEY75107.1 - 8.1e-74 249.1 24.8 9.6e-74 248.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY75107.1 - 1.4e-30 106.5 56.8 3.9e-22 78.7 17.1 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KEY75107.1 - 1.6e-05 23.6 2.1 1.6e-05 23.6 2.1 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.18 KEY75108.1 - 1.5e-143 478.5 0.0 2e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 KEY75108.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Fungal_trans PF04082.18 KEY75109.1 - 6.6e-12 45.0 0.1 3.7e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY75109.1 - 5.2e-07 29.7 9.7 9.1e-07 28.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TYA PF01021.19 KEY75109.1 - 0.055 13.8 4.3 0.096 13.0 2.3 2.2 2 0 0 2 2 2 0 TYA transposon protein HET PF06985.11 KEY75111.1 - 2.2e-24 86.4 0.3 3.9e-24 85.7 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KEY75114.1 - 3.5e-36 124.5 0.4 4.3e-36 124.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75114.1 - 2.6e-23 82.8 0.1 3.2e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KEY75114.1 - 0.00037 20.0 0.0 0.00052 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MM_CoA_mutase PF01642.22 KEY75114.1 - 0.1 11.2 0.5 4.8 5.6 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl-CoA mutase Pkinase PF00069.25 KEY75115.1 - 1.3e-11 44.4 0.0 2.6e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY75115.1 - 3e-05 23.4 0.0 6.4e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase zf-LITAF-like PF10601.9 KEY75116.1 - 4.3e-07 30.1 0.0 6.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Prok-RING_4 PF14447.6 KEY75116.1 - 0.17 11.7 0.7 0.59 10.0 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FAD_binding_4 PF01565.23 KEY75117.1 - 3.9e-20 72.0 1.3 6.5e-20 71.3 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY75117.1 - 0.003 17.6 0.1 0.0062 16.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like GHL6 PF14871.6 KEY75118.1 - 1.5e-26 93.2 0.0 2.6e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 GHL10 PF02638.15 KEY75118.1 - 3.2e-06 26.4 0.0 4.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_42 PF02449.15 KEY75118.1 - 3e-05 23.6 0.3 6.3e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KEY75118.1 - 3.6e-05 23.4 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain HET PF06985.11 KEY75119.1 - 8.3e-37 126.8 0.6 1.4e-36 126.0 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEY75120.1 - 8e-25 87.5 60.6 1.1e-24 87.1 57.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEY75120.1 - 1.1e-06 27.9 15.4 1.1e-06 27.9 15.4 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter adh_short PF00106.25 KEY75121.1 - 3.8e-18 65.7 0.0 1.7e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75121.1 - 5.3e-10 39.3 0.0 5.3e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY75121.1 - 1.9e-06 27.9 0.1 5.5e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF3237 PF11578.8 KEY75122.1 - 3.9e-20 72.2 0.0 4.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.25 KEY75123.1 - 1.3e-08 34.5 0.1 1.9e-08 34.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75123.1 - 5.9e-08 32.6 0.0 7.6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEY75123.1 - 0.00052 19.6 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEY75123.1 - 0.013 15.5 0.2 0.02 14.8 0.1 1.5 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 KEY75123.1 - 0.097 12.2 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.19 KEY75123.1 - 0.15 11.5 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PS-DH PF14765.6 KEY75124.1 - 5.8e-70 235.9 0.1 1.4e-69 234.6 0.1 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEY75124.1 - 4.7e-67 226.2 0.0 9.4e-67 225.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEY75124.1 - 5.8e-60 203.4 0.3 1.3e-59 202.4 0.3 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEY75124.1 - 3.2e-58 196.6 0.8 1e-57 194.9 0.5 2.1 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEY75124.1 - 1e-28 99.7 0.9 2.7e-28 98.3 0.2 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEY75124.1 - 2.4e-21 76.3 0.1 1.4e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEY75124.1 - 2.3e-08 33.7 0.1 2.3e-08 33.7 0.1 2.3 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KEY75124.1 - 6e-06 26.3 6.1 1.7e-05 24.8 0.3 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEY75124.1 - 8.5e-05 22.4 0.4 0.00023 21.0 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KEY75124.1 - 0.00038 19.9 0.2 0.00082 18.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KEY75124.1 - 0.0011 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 KEY75124.1 - 0.015 15.1 0.3 0.053 13.4 0.3 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox_3 PF13738.6 KEY75126.1 - 4.4e-13 49.2 0.0 4.3e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEY75126.1 - 1.6e-10 40.1 0.0 0.00014 20.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEY75126.1 - 8.8e-09 35.0 0.0 6.6e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEY75126.1 - 5e-08 33.1 0.0 0.048 13.7 0.0 4.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KEY75126.1 - 7.4e-07 28.6 0.0 8.8e-06 25.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEY75126.1 - 4.3e-06 26.8 0.0 1.8e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEY75126.1 - 0.00022 20.1 0.0 0.21 10.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KEY75126.1 - 0.00074 18.7 0.0 0.0056 15.8 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEY75126.1 - 0.0091 15.3 0.2 0.036 13.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KEY75126.1 - 0.011 15.4 0.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEY75126.1 - 0.099 13.2 0.1 23 5.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 KEY75127.1 - 2.2e-21 76.1 2.2 3.5e-21 75.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEY75127.1 - 4.6e-10 39.4 0.1 4.6e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 KEY75127.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_3 PF01494.19 KEY75128.1 - 4.2e-28 98.6 0.0 9.3e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEY75128.1 - 2e-05 24.8 0.1 4.5e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEY75128.1 - 4.1e-05 23.0 0.8 0.00034 20.0 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY75128.1 - 0.0014 17.9 1.9 0.023 13.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEY75128.1 - 0.002 17.3 1.1 0.0037 16.4 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEY75128.1 - 0.0061 16.2 1.0 0.034 13.7 0.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEY75128.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KEY75128.1 - 0.036 14.6 0.3 0.087 13.4 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEY75128.1 - 0.097 11.7 0.0 0.77 8.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 KEY75128.1 - 0.12 11.0 0.5 0.31 9.7 0.4 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KEY75128.1 - 0.15 11.2 0.2 0.28 10.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KEY75128.1 - 0.16 11.2 0.1 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KEY75128.1 - 0.21 10.9 0.7 0.39 10.0 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEY75128.1 - 0.27 10.3 0.8 0.43 9.6 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3237 PF11578.8 KEY75129.1 - 3.5e-17 62.6 0.0 3.9e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Fungal_trans PF04082.18 KEY75130.1 - 4.9e-16 58.6 0.0 1.3e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEY75130.1 - 7.8e-10 38.7 10.1 1.5e-09 37.8 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KEY75132.1 - 1.3e-20 74.2 0.0 2.8e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEY75132.1 - 5.3e-15 56.6 0.4 8.1e-15 56.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEY75132.1 - 7.2e-15 54.9 0.0 5.5e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEY75132.1 - 0.0065 15.2 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S15 PF02129.18 KEY75132.1 - 0.038 13.6 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KEY75132.1 - 0.096 11.3 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) HD PF01966.22 KEY75133.1 - 0.0034 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 HD domain TOC159_MAD PF11886.8 KEY75133.1 - 0.12 11.3 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain DJ-1_PfpI PF01965.24 KEY75134.1 - 4.9e-16 59.0 0.0 7.5e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family Lipase_GDSL_2 PF13472.6 KEY75135.1 - 2.3e-13 50.9 1.4 3.2e-13 50.5 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEY75135.1 - 2.4e-05 24.4 0.3 5.6e-05 23.2 0.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4470 PF14737.6 KEY75136.1 - 7.7e-23 80.5 0.0 1.6e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEY75136.1 - 4.8e-05 23.3 7.9 0.00012 22.1 7.9 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KEY75136.1 - 0.0065 16.3 2.7 0.018 14.9 2.7 1.8 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.6 KEY75136.1 - 0.033 14.3 5.1 0.082 13.0 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RTA1 PF04479.13 KEY75137.1 - 9.8e-64 214.8 12.8 9.8e-64 214.8 12.8 1.6 1 1 1 2 2 2 1 RTA1 like protein Sulfotransfer_4 PF17784.1 KEY75138.1 - 2.5e-61 207.3 0.0 2.9e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEY75138.1 - 0.0033 17.8 0.0 0.25 11.7 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family L6_membrane PF05805.12 KEY75138.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 L6 membrane protein GATase_5 PF13507.6 KEY75140.1 - 2.3e-101 338.3 0.0 3.2e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KEY75140.1 - 3.9e-36 124.5 0.8 2.3e-23 83.0 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KEY75140.1 - 1.3e-21 76.7 0.0 2.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KEY75140.1 - 2.4e-20 72.8 0.0 5.9e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Thioredoxin PF00085.20 KEY75141.1 - 4.1e-27 94.2 0.0 4.8e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEY75141.1 - 3.4e-06 27.5 0.2 4.3e-05 23.9 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KEY75141.1 - 5e-05 22.8 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KEY75141.1 - 5.1e-05 23.4 0.0 6.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KEY75141.1 - 0.00036 20.3 0.0 0.00039 20.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KEY75141.1 - 0.00076 19.8 0.0 0.34 11.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 KEY75141.1 - 0.048 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 KEY75141.1 - 0.059 13.3 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family KaiB PF07689.12 KEY75141.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiB domain Redoxin PF08534.10 KEY75141.1 - 0.097 12.4 0.1 0.27 11.0 0.1 1.7 1 1 1 2 2 2 0 Redoxin DUF953 PF06110.11 KEY75141.1 - 0.1 12.3 0.2 0.78 9.4 0.2 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Sugar_tr PF00083.24 KEY75142.1 - 3.2e-99 332.8 15.2 3.9e-99 332.6 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEY75142.1 - 1.8e-19 69.9 29.4 1.1e-16 60.7 19.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEY75142.1 - 0.00036 19.2 23.0 0.0077 14.8 8.5 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Ribonuc_L-PSP PF01042.21 KEY75143.1 - 3.2e-18 65.9 0.0 6.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP PAP_assoc PF03828.19 KEY75143.1 - 1.6e-08 34.6 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEY75143.1 - 1.9e-08 34.5 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GMC_oxred_N PF00732.19 KEY75144.1 - 2.9e-58 197.6 0.0 3.9e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEY75144.1 - 4e-33 115.0 0.1 1.2e-32 113.4 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEY75144.1 - 4.1e-05 23.7 0.1 9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEY75144.1 - 0.0001 22.0 0.5 0.0012 18.5 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEY75144.1 - 0.00029 20.0 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEY75144.1 - 0.00029 20.0 0.1 0.01 15.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEY75144.1 - 0.0033 16.7 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEY75144.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEY75144.1 - 0.076 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KEY75144.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEY75144.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.7 KEY75145.1 - 0.0019 18.1 1.9 0.004 17.0 1.9 1.6 1 0 0 1 1 1 1 F-box-like zf-RING_14 PF17978.1 KEY75145.1 - 0.083 13.3 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_61 PF03443.14 KEY75146.1 - 3.3e-39 135.0 0.0 4.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.6 KEY75147.1 - 0.0017 18.6 0.2 0.0045 17.2 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEY75147.1 - 0.012 15.4 1.6 0.028 14.2 1.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY75147.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_2 PF07719.17 KEY75147.1 - 0.026 14.6 1.9 0.08 13.1 1.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEY75147.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEY75147.1 - 0.28 11.5 0.9 0.83 10.0 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEY75148.1 - 5.4e-08 32.4 0.1 1.2e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily GUN4 PF05419.12 KEY75148.1 - 0.078 13.1 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 GUN4-like PNP_UDP_1 PF01048.20 KEY75150.1 - 2e-09 37.1 0.0 5.9e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Glyco_hyd_65N_2 PF14498.6 KEY75151.1 - 0.062 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ank_2 PF12796.7 KEY75153.1 - 9.6e-35 119.0 0.1 4.8e-09 36.7 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY75153.1 - 2.4e-32 110.9 3.1 8.2e-05 23.1 0.0 7.1 6 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY75153.1 - 5e-30 100.2 5.3 0.0001 22.4 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KEY75153.1 - 1.8e-28 97.7 15.8 6.9e-05 23.1 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KEY75153.1 - 9.2e-27 92.8 7.8 7.7e-10 38.8 0.0 7.8 7 1 1 8 8 8 6 Ankyrin repeats (many copies) F-box-like PF12937.7 KEY75153.1 - 0.03 14.2 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 F-box-like HMGL-like PF00682.19 KEY75157.1 - 8.8e-62 209.0 2.2 7.7e-39 133.8 0.0 2.2 2 0 0 2 2 2 2 HMGL-like Trp_syntA PF00290.20 KEY75157.1 - 0.0036 16.2 0.0 0.55 9.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan synthase alpha chain Metallophos PF00149.28 KEY75158.1 - 6.4e-09 36.6 0.5 9.1e-09 36.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEY75158.1 - 8.5e-06 26.1 0.2 0.00018 21.7 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aromatic_hydrox PF11723.8 KEY75158.1 - 0.1 12.1 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase NmrA PF05368.13 KEY75159.1 - 5.4e-32 111.2 0.0 1.2e-31 110.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEY75159.1 - 5.7e-12 45.9 0.1 7.4e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEY75159.1 - 3.9e-05 23.2 0.0 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEY75159.1 - 0.0015 18.0 0.2 0.0028 17.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Herpes_IR6 PF06307.12 KEY75159.1 - 0.017 14.7 0.1 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus IR6 protein F420_oxidored PF03807.17 KEY75159.1 - 0.044 14.4 0.2 0.091 13.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LytR_C PF13399.6 KEY75159.1 - 0.1 13.6 0.7 23 6.1 0.4 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator GDP_Man_Dehyd PF16363.5 KEY75159.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KEY75159.1 - 0.12 12.6 0.1 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.19 KEY75159.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KEY75159.1 - 0.16 11.5 1.0 0.39 10.2 0.3 1.8 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KEY75160.1 - 9.8e-22 77.5 0.0 1.6e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEY75160.1 - 6e-11 42.9 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEY75160.1 - 2.2e-10 40.5 0.2 4.3e-09 36.3 0.2 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEY75160.1 - 3.9e-07 30.6 0.0 7.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY75160.1 - 0.00027 21.6 0.0 0.00069 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEY75160.1 - 0.0034 16.9 0.0 0.0077 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEY75160.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KEY75160.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KEY75160.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KEY75160.1 - 0.069 12.5 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KEY75160.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Yip1 PF04893.17 KEY75162.1 - 0.00056 19.7 15.0 0.1 12.3 9.3 2.6 2 1 0 2 2 2 2 Yip1 domain RCC1 PF00415.18 KEY75163.1 - 2.4e-70 233.0 2.2 5.4e-13 49.3 0.2 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEY75163.1 - 1.3e-41 139.6 35.4 2.9e-10 39.7 1.4 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KEY75163.1 - 0.0015 18.4 0.4 11 5.9 0.0 4.2 3 1 1 4 4 4 2 Peptidase family C25, C terminal ig-like domain GbpA_2 PF18416.1 KEY75164.1 - 0.052 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 Trypsin PF00089.26 KEY75165.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin HET PF06985.11 KEY75167.1 - 1.8e-29 102.9 5.3 3e-29 102.3 5.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEY75169.1 - 2.4e-33 115.6 30.9 4.4e-33 114.7 30.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 KEY75170.1 - 9.7e-160 532.0 0.0 1.3e-159 531.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KEY75170.1 - 2.5e-22 79.2 0.2 5e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KEY75170.1 - 2.3e-12 47.0 0.0 5.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HpcH_HpaI PF03328.14 KEY75173.1 - 1.6e-23 83.0 0.0 1.8e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DMAP1 PF05499.12 KEY75173.1 - 0.048 13.6 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DNA_pol_phi PF04931.13 KEY75174.1 - 6.3 4.8 5.8 8.3 4.4 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CHAT PF12770.7 KEY75175.1 - 1.1e-09 38.1 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 KEY75175.1 - 3.7e-09 36.7 0.2 1.4e-08 34.9 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEY75175.1 - 0.032 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KEY75175.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 KEY75175.1 - 0.14 12.2 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CorA PF01544.18 KEY75176.1 - 1.6e-08 34.2 0.3 3.3e-08 33.2 0.1 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MASE5 PF17178.4 KEY75176.1 - 0.072 12.9 2.0 0.17 11.7 2.0 1.6 1 0 0 1 1 1 0 Membrane-associated sensor CENP-T_C PF15511.6 KEY75176.1 - 0.17 12.0 0.3 0.34 11.1 0.3 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold FMO-like PF00743.19 KEY75177.1 - 8.1e-32 110.3 0.0 3.3e-15 55.5 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEY75177.1 - 7.6e-21 74.7 0.1 3.8e-13 49.4 0.0 3.6 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY75177.1 - 1.6e-14 53.9 0.1 1e-13 51.2 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEY75177.1 - 5.2e-12 46.0 4.2 3.3e-05 23.6 1.8 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEY75177.1 - 1.7e-09 37.5 2.0 4e-05 23.1 0.1 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEY75177.1 - 3.2e-09 36.9 0.0 8.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEY75177.1 - 2e-07 31.5 2.5 0.00018 22.0 0.9 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEY75177.1 - 4.9e-07 29.2 2.0 3.7e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEY75177.1 - 2.5e-06 27.6 3.3 0.00045 20.2 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEY75177.1 - 3.6e-06 26.3 5.1 0.00083 18.6 1.6 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KEY75177.1 - 6.4e-06 25.1 0.3 0.0039 15.9 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 KEY75177.1 - 0.0013 18.1 1.8 0.0021 17.4 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 KEY75177.1 - 0.0016 18.1 0.0 0.069 12.8 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KEY75177.1 - 0.0047 17.0 1.3 0.63 10.1 0.2 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KEY75177.1 - 0.0069 15.8 2.3 0.012 15.0 2.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEY75177.1 - 0.033 13.3 2.5 0.041 12.9 1.2 1.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KEY75177.1 - 0.08 12.2 0.7 0.16 11.2 0.7 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KEY75177.1 - 0.085 12.7 1.5 0.17 11.7 1.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KEY75177.1 - 0.11 13.0 0.3 6.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KEY75177.1 - 0.61 9.4 3.0 0.6 9.4 1.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GAS PF13851.6 KEY75178.1 - 6e-07 29.0 81.6 8e-05 22.1 18.1 4.8 1 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KEY75178.1 - 8.5e-05 21.6 29.6 8.5e-05 21.6 29.6 4.5 2 2 3 5 5 5 4 Spc7 kinetochore protein BLOC1_2 PF10046.9 KEY75178.1 - 0.0019 18.5 0.7 0.0019 18.5 0.7 6.8 2 2 2 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KEY75178.1 - 0.002 18.6 20.2 0.002 18.6 20.2 5.4 1 1 4 5 5 5 1 Fez1 MscS_porin PF12795.7 KEY75178.1 - 0.0025 17.4 26.0 0.0025 17.4 26.0 5.2 1 1 3 4 4 3 1 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 KEY75178.1 - 0.0025 17.7 13.3 0.0025 17.7 13.3 4.6 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KEY75178.1 - 0.0031 17.8 109.7 0.0039 17.4 8.7 6.2 3 2 3 6 6 5 3 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.11 KEY75178.1 - 0.0049 16.7 3.9 0.36 10.7 0.8 3.9 4 1 1 5 5 4 1 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 KEY75178.1 - 0.017 15.2 0.8 0.017 15.2 0.8 8.4 5 5 5 10 10 9 0 bZIP transcription factor FtsH_ext PF06480.15 KEY75178.1 - 0.11 12.8 0.7 0.61 10.5 0.7 2.3 1 0 0 1 1 1 0 FtsH Extracellular SAP PF02037.27 KEY75178.1 - 0.15 11.9 3.5 0.31 10.9 0.5 3.2 2 0 0 2 2 2 0 SAP domain ADIP PF11559.8 KEY75178.1 - 0.28 11.3 86.5 1 9.4 3.8 6.4 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 KEY75178.1 - 0.34 9.4 43.3 0.031 12.9 10.7 3.7 2 2 1 3 3 3 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 KEY75178.1 - 0.49 10.4 88.6 0.33 11.0 4.6 7.7 3 3 4 8 8 8 0 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 KEY75178.1 - 0.7 8.7 86.9 0.1 11.4 39.7 3.5 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 KEY75178.1 - 1 8.6 80.4 0.061 12.6 7.6 5.4 2 2 2 5 5 5 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 KEY75178.1 - 5.4 7.4 25.9 0.47 10.8 0.4 5.9 3 1 1 5 5 5 0 TSC-22/dip/bun family DUF4407 PF14362.6 KEY75178.1 - 8.6 5.6 87.5 3 7.1 22.4 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) VWA PF00092.28 KEY75179.1 - 0.00025 21.4 0.0 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEY75179.1 - 0.0012 19.4 0.0 2.5 8.8 0.0 2.9 2 0 0 2 2 2 2 von Willebrand factor type A domain Peptidase_C1 PF00112.23 KEY75179.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Papain family cysteine protease Arg_decarbox_C PF17944.1 KEY75179.1 - 0.17 12.5 0.2 0.88 10.2 0.0 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension MFS_1 PF07690.16 KEY75181.1 - 5.4e-13 48.6 36.6 5.4e-13 48.6 36.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.23 KEY75182.1 - 1.1e-30 107.0 0.8 1.4e-30 106.6 0.1 1.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEY75182.1 - 0.00034 20.7 0.1 0.00097 19.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KEY75182.1 - 0.099 13.1 0.1 0.15 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1917 PF08939.10 KEY75182.1 - 0.15 11.9 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) GED PF02212.18 KEY75183.1 - 0.0023 18.1 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF2757 PF10955.8 KEY75183.1 - 0.023 14.9 0.2 0.047 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) AvrM_N PF18247.1 KEY75183.1 - 0.037 14.0 0.4 0.58 10.2 0.0 2.7 2 1 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain DUF4883 PF16224.5 KEY75183.1 - 0.1 12.9 2.1 0.14 12.4 2.1 1.2 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) LAMTOR PF15454.6 KEY75183.1 - 0.3 11.7 2.2 5.3 7.7 0.5 2.7 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Annexin PF00191.20 KEY75184.1 - 4.8e-44 148.3 0.6 1.3e-11 44.4 0.0 4.3 4 0 0 4 4 4 4 Annexin TPR_8 PF13181.6 KEY75184.1 - 0.098 12.9 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HET PF06985.11 KEY75186.1 - 4.7e-31 108.1 0.3 8.9e-31 107.2 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAO PF01266.24 KEY75187.1 - 9.7e-27 94.5 5.4 1.1e-26 94.3 5.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEY75187.1 - 0.023 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEY75187.1 - 0.058 12.6 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2196 PF09962.9 KEY75187.1 - 0.062 13.3 0.7 0.13 12.3 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) AlaDh_PNT_C PF01262.21 KEY75187.1 - 0.16 11.3 1.0 0.24 10.6 0.9 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Solute_trans_a PF03619.16 KEY75188.1 - 2.8e-71 240.1 20.9 3.4e-71 239.9 20.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Colicin_V PF02674.16 KEY75188.1 - 0.26 11.2 5.4 1.1 9.2 1.8 2.9 3 0 0 3 3 3 0 Colicin V production protein DUF368 PF04018.13 KEY75190.1 - 0.024 14.2 1.2 0.034 13.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) DUF2975 PF11188.8 KEY75190.1 - 0.19 11.6 5.7 0.29 11.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) p450 PF00067.22 KEY75191.1 - 6.6e-66 223.0 0.0 8.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KEY75193.1 - 3.3e-30 105.4 4.1 7.9e-30 104.1 4.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Con-6 PF10346.9 KEY75194.1 - 4.5e-15 55.4 0.3 1.2e-14 54.0 0.3 1.8 1 0 0 1 1 1 1 Conidiation protein 6 F-box-like PF12937.7 KEY75196.1 - 0.004 17.0 0.0 0.015 15.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like Exonuc_VIII PF06630.11 KEY75196.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Beta-lactamase PF00144.24 KEY75197.1 - 8.4e-41 140.3 0.7 1.3e-40 139.7 0.7 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KEY75197.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_115 PF15979.5 KEY75198.1 - 2.2e-134 448.2 0.2 3e-134 447.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEY75198.1 - 2.5e-51 173.9 0.0 4.8e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KEY75198.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus ERAP1_C PF11838.8 KEY75198.1 - 0.022 14.3 0.6 0.073 12.6 0.6 1.8 2 0 0 2 2 2 0 ERAP1-like C-terminal domain S_layer_C PF05124.12 KEY75198.1 - 0.052 13.5 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region CBM_1 PF00734.18 KEY75199.1 - 1e-11 44.6 5.3 2e-11 43.6 5.3 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain FAT PF02259.23 KEY75200.1 - 2.4e-132 441.4 7.1 5.8e-132 440.1 7.1 1.7 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 KEY75200.1 - 6.7e-76 253.7 7.7 2.8e-72 241.9 0.4 5.0 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KEY75200.1 - 6.4e-74 248.9 0.1 1.2e-73 248.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KEY75200.1 - 1.3e-45 153.8 0.2 1.3e-45 153.8 0.2 3.3 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KEY75200.1 - 5.7e-21 72.8 6.8 0.0001 22.2 0.0 11.1 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 KEY75200.1 - 2.5e-16 59.8 8.4 5.3e-05 23.5 0.0 8.2 9 0 0 9 9 7 3 HEAT repeats HEAT_EZ PF13513.6 KEY75200.1 - 1.1e-13 51.4 7.9 0.00016 22.1 0.0 9.9 8 2 2 10 10 9 2 HEAT-like repeat FATC PF02260.20 KEY75200.1 - 2.6e-13 49.5 0.2 9.2e-13 47.8 0.2 2.1 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 KEY75200.1 - 1e-09 38.6 1.3 0.0071 16.4 0.1 6.7 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEY75200.1 - 3.2e-09 37.3 0.0 8.6 7.0 0.0 7.7 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KEY75200.1 - 3e-06 26.1 8.6 0.012 14.2 0.1 5.5 4 1 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.8 KEY75200.1 - 0.00012 21.7 9.5 7 6.1 0.0 6.8 6 1 1 7 7 7 2 CLASP N terminal Cohesin_HEAT PF12765.7 KEY75200.1 - 0.069 13.5 0.8 52 4.3 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.6 KEY75200.1 - 0.12 12.7 4.6 11 6.3 0.0 5.1 6 0 0 6 6 5 0 FANCI solenoid 2 ANAPC3 PF12895.7 KEY75200.1 - 0.23 11.7 4.1 6.5 7.0 0.0 4.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Baculo_PEP_C PF04513.12 KEY75200.1 - 0.42 10.6 3.7 0.52 10.3 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec7_N PF12783.7 KEY75200.1 - 6.8 6.6 12.1 21 5.0 2.3 4.6 5 2 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Sugar_tr PF00083.24 KEY75201.1 - 2.6e-95 319.9 13.1 3.6e-95 319.5 13.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PRKCSH-like PF12999.7 KEY75201.1 - 5.5e-41 140.3 6.9 1.4e-24 86.8 0.4 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KEY75201.1 - 4.1e-30 104.5 0.4 8.9e-30 103.4 0.4 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1 PF07690.16 KEY75201.1 - 5.4e-27 94.6 51.1 2.1e-23 82.9 27.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PRKCSH PF07915.13 KEY75201.1 - 7.1e-11 43.0 1.1 2e-10 41.5 1.1 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.10 KEY75201.1 - 0.00071 19.5 0.3 0.00071 19.5 0.3 1.7 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain Flagellar_rod PF05149.12 KEY75201.1 - 0.0062 16.0 6.4 0.013 15.0 6.4 1.4 1 0 0 1 1 1 1 Paraflagellar rod protein ATG27 PF09451.10 KEY75201.1 - 0.0096 15.8 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Mod_r PF07200.13 KEY75201.1 - 0.037 14.1 0.2 0.037 14.1 0.2 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GTP-bdg_M PF16360.5 KEY75201.1 - 0.11 13.1 5.2 0.18 12.4 3.5 2.3 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF948 PF06103.11 KEY75201.1 - 0.12 12.6 1.3 5.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KEY75201.1 - 0.56 9.5 18.2 0.25 10.6 6.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KEY75201.1 - 0.59 10.7 17.3 3.9 8.0 3.9 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region Ldl_recept_a PF00057.18 KEY75201.1 - 8.7 6.7 13.7 0.23 11.7 2.2 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DivIC PF04977.15 KEY75201.1 - 9.6 6.1 13.8 31 4.4 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator GCIP PF13324.6 KEY75202.1 - 1.2e-18 67.7 0.1 3.7e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting CDC45 PF02724.14 KEY75202.1 - 0.048 12.0 0.4 0.061 11.6 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KEY75202.1 - 0.082 11.1 1.3 0.11 10.7 1.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nrap_D6 PF17407.2 KEY75202.1 - 0.093 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Nrap protein domain 6 RRN3 PF05327.11 KEY75202.1 - 0.29 9.6 3.9 0.48 8.9 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KEY75202.1 - 8.8 4.3 11.7 13 3.7 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi mRNA_triPase PF02940.15 KEY75205.1 - 4.1e-57 193.4 0.2 5.5e-57 193.0 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain AA_permease_2 PF13520.6 KEY75206.1 - 9.9e-54 182.8 25.4 8.8e-53 179.6 25.4 2.4 1 1 0 1 1 1 1 Amino acid permease Xan_ur_permease PF00860.20 KEY75207.1 - 2.2e-60 204.4 28.2 2.6e-59 200.9 28.2 2.0 1 1 0 1 1 1 1 Permease family Cupin_4 PF08007.12 KEY75207.1 - 0.042 13.3 0.2 0.075 12.5 0.2 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.25 KEY75209.1 - 0.00035 20.0 0.0 0.00084 18.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KEY75210.1 - 3.8e-06 27.1 0.0 0.012 15.9 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEY75210.1 - 0.0046 17.8 9.1 11 7.0 0.5 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KEY75210.1 - 0.0056 16.3 0.0 0.024 14.2 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 KEY75210.1 - 0.0066 15.1 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Antimicrobial22 PF16047.5 KEY75210.1 - 0.011 15.6 1.3 0.024 14.5 1.3 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide CDC45 PF02724.14 KEY75210.1 - 0.031 12.6 6.5 0.041 12.2 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KEY75210.1 - 0.037 13.7 5.1 0.055 13.2 5.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 KEY75210.1 - 0.24 10.0 14.1 0.32 9.5 14.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 KEY75210.1 - 0.72 9.5 13.6 1.1 9.0 13.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KEY75210.1 - 2.2 8.1 8.3 4 7.3 8.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 KEY75210.1 - 4.5 5.4 12.4 6 5.0 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KEY75210.1 - 5.5 5.0 18.4 7.6 4.5 18.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cupin_2 PF07883.11 KEY75211.1 - 0.00039 20.1 0.1 0.00072 19.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KEY75211.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Cupin Glyco_hydro_18 PF00704.28 KEY75212.1 - 1e-59 202.8 0.0 1.3e-59 202.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 KEY75212.1 - 0.017 15.5 0.1 0.042 14.3 0.1 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GDPD PF03009.17 KEY75213.1 - 1.8e-10 41.0 0.0 1.6e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family MARVEL PF01284.23 KEY75214.1 - 3.9e-11 43.2 29.3 4.7e-11 42.9 29.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_U4 PF03419.13 KEY75214.1 - 4.1 6.6 12.0 4.8 6.4 12.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Presenilin PF01080.17 KEY75215.1 - 7.8 5.1 6.0 14 4.3 6.0 1.3 1 0 0 1 1 1 0 Presenilin MARVEL PF01284.23 KEY75216.1 - 2e-06 27.9 16.0 2.7e-06 27.4 16.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 KEY75216.1 - 0.00019 21.7 2.8 0.00019 21.7 2.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 KEY75216.1 - 2.2 8.1 17.1 0.16 11.8 10.5 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling PalH PF08733.10 KEY75216.1 - 4.8 6.1 7.2 7.7 5.4 7.2 1.3 1 0 0 1 1 1 0 PalH/RIM21 DHHC PF01529.20 KEY75216.1 - 4.9 7.3 11.2 16 5.6 7.0 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase RDD PF06271.12 KEY75216.1 - 9 6.5 16.7 0.34 11.1 4.0 2.8 1 1 1 2 2 2 0 RDD family Diphthamide_syn PF01866.17 KEY75218.1 - 2.5e-89 299.7 0.0 3.1e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MutS_V PF00488.21 KEY75219.1 - 8.5e-67 224.8 0.2 1.7e-66 223.8 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEY75219.1 - 2e-42 145.6 0.0 6.3e-42 144.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KEY75219.1 - 4.7e-32 110.6 0.1 1.2e-31 109.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KEY75219.1 - 3.3e-13 49.8 0.1 8e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KEY75219.1 - 4e-12 46.6 0.0 2.4e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_23 PF13476.6 KEY75219.1 - 0.018 15.5 2.4 0.07 13.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KEY75219.1 - 0.018 14.8 1.8 0.14 12.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MPP6 PF10175.9 KEY75219.1 - 0.034 14.6 2.0 0.11 13.0 2.0 1.9 1 0 0 1 1 1 0 M-phase phosphoprotein 6 AAA_27 PF13514.6 KEY75219.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEY75219.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SPT6_acidic PF14632.6 KEY75219.1 - 0.53 10.9 6.4 2.1 9.0 6.4 2.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 HC2 PF07382.11 KEY75220.1 - 2.2e-06 27.9 14.3 2.2e-06 27.9 14.3 2.5 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Peptidase_S8 PF00082.22 KEY75222.1 - 7.7e-26 91.0 0.7 1.9e-25 89.7 0.7 1.6 1 1 0 1 1 1 1 Subtilase family F-box-like PF12937.7 KEY75223.1 - 0.015 15.2 2.5 0.017 15.0 0.2 2.4 3 0 0 3 3 3 0 F-box-like FTA2 PF13095.6 KEY75224.1 - 3.6e-48 164.0 0.0 4.6e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 HDOD PF08668.12 KEY75225.1 - 0.21 11.0 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 HDOD domain Glyco_hydro_28 PF00295.17 KEY75226.1 - 3.8e-111 371.3 22.4 4.8e-111 370.9 22.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_16 PF00722.21 KEY75226.1 - 4.9e-08 32.7 0.0 2.1e-07 30.6 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 RTBV_P12 PF06361.11 KEY75227.1 - 0.054 13.9 1.7 1.4 9.4 0.2 2.4 1 1 0 2 2 2 0 Rice tungro bacilliform virus P12 protein CHAT PF12770.7 KEY75228.1 - 5.6e-33 114.6 0.1 9.8e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KEY75228.1 - 8.3e-06 26.0 21.8 0.11 12.8 1.0 8.3 4 4 3 8 8 8 3 Tetratricopeptide repeat Peptidase_C50 PF03568.17 KEY75228.1 - 0.03 13.5 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C50 TPR_11 PF13414.6 KEY75228.1 - 0.18 11.5 1.5 44 3.9 0.0 4.7 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 KEY75228.1 - 0.63 10.0 27.5 11 6.1 0.1 9.3 10 0 0 10 10 10 0 Tetratricopeptide repeat Lactamase_B PF00753.27 KEY75229.1 - 6.5e-16 58.9 0.3 3.5e-15 56.5 0.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEY75229.1 - 0.0073 15.8 0.2 0.014 14.9 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.32 KEY75230.1 - 2.2e-105 341.6 66.5 2.2e-10 40.9 0.5 13.3 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY75230.1 - 2.9e-37 126.8 25.0 6.7e-06 26.3 0.4 11.2 2 1 8 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEY75230.1 - 5.1e-24 85.0 0.1 1e-23 84.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KEY75230.1 - 2.5e-14 52.8 40.6 0.03 13.0 0.2 11.3 1 1 11 12 12 12 8 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEY75230.1 - 2.2e-07 30.2 30.4 0.019 14.0 5.7 8.9 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 KEY75230.1 - 6.1e-07 29.9 5.1 0.0013 19.1 0.3 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_11 PF13086.6 KEY75230.1 - 0.063 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40_like PF17005.5 KEY75230.1 - 0.16 11.3 0.0 26 4.0 0.0 3.1 3 1 0 3 3 3 0 WD40-like domain CXCXC PF03128.14 KEY75230.1 - 0.5 10.9 4.2 1.2 9.8 0.8 3.6 5 0 0 5 5 5 0 CXCXC repeat Stomoxyn PF11585.8 KEY75231.1 - 7.6 6.6 8.2 2.7e+02 1.7 8.2 2.6 1 1 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Ank_2 PF12796.7 KEY75233.1 - 6e-11 42.8 0.9 1.4e-10 41.6 0.3 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY75233.1 - 3.1e-09 37.2 1.1 8.4e-05 23.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY75233.1 - 1.7e-05 25.0 1.1 0.8 10.3 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KEY75233.1 - 0.00034 20.8 1.1 0.16 12.3 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY75233.1 - 0.003 17.9 0.1 7.4 7.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KEY75234.1 - 3.8e-22 78.7 0.4 1.6e-08 35.0 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEY75234.1 - 1.1e-12 48.2 11.2 1.4e-07 31.9 0.2 6.8 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEY75234.1 - 7.5e-12 44.4 3.6 0.0015 18.9 0.0 7.7 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KEY75234.1 - 2.1e-10 40.6 5.5 0.00017 21.8 0.2 5.0 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KEY75234.1 - 2e-08 34.3 10.9 0.023 15.1 0.1 6.9 7 1 0 7 7 7 2 Ankyrin repeat Pox_T4_C PF04490.12 KEY75234.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus SGS PF05002.15 KEY75237.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 SGS domain Glyco_hydro_101 PF12905.7 KEY75238.1 - 0.19 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase MLVIN_C PF18697.1 KEY75239.1 - 0.00056 20.0 0.2 0.0035 17.4 0.0 2.1 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain TPR_10 PF13374.6 KEY75240.1 - 2.2e-200 644.1 20.5 1.1e-12 47.3 0.0 16.6 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_12 PF13424.6 KEY75240.1 - 3.3e-186 604.1 52.4 5.5e-17 61.8 0.1 14.7 1 1 15 16 16 16 16 Tetratricopeptide repeat TPR_MalT PF17874.1 KEY75240.1 - 1.4e-48 166.0 53.6 5.1e-11 42.5 1.0 7.3 1 1 10 11 11 11 11 MalT-like TPR region TPR_4 PF07721.14 KEY75240.1 - 1.1e-39 130.9 0.0 0.84 10.4 0.0 15.8 16 0 0 16 16 15 9 Tetratricopeptide repeat TPR_1 PF00515.28 KEY75240.1 - 3.2e-39 131.2 28.3 0.0056 16.5 0.0 16.2 17 0 0 17 17 16 11 Tetratricopeptide repeat TPR_17 PF13431.6 KEY75240.1 - 2.9e-35 118.1 13.1 0.38 11.2 0.0 16.0 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_7 PF13176.6 KEY75240.1 - 1.9e-30 102.6 31.1 0.03 14.4 0.1 15.7 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEY75240.1 - 3.7e-28 95.3 18.6 0.052 13.7 0.0 15.6 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEY75240.1 - 4.7e-22 76.3 29.7 0.29 11.5 0.0 15.9 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEY75240.1 - 1.5e-14 54.3 32.5 0.03 14.8 0.2 10.3 2 1 12 14 14 14 5 Tetratricopeptide repeat NB-ARC PF00931.22 KEY75240.1 - 9.2e-14 51.2 0.0 2.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_15 PF13429.6 KEY75240.1 - 1.4e-12 47.4 21.9 4.7 6.3 0.1 13.4 4 3 10 14 14 14 1 Tetratricopeptide repeat PPR PF01535.20 KEY75240.1 - 3.2e-11 42.7 6.6 19 5.8 0.0 11.7 14 0 0 14 14 13 0 PPR repeat TPR_16 PF13432.6 KEY75240.1 - 5.1e-11 43.0 33.6 0.61 10.8 0.1 13.2 10 4 1 11 11 11 3 Tetratricopeptide repeat NACHT PF05729.12 KEY75240.1 - 7.4e-08 32.5 0.0 3e-07 30.5 0.0 2.2 1 0 0 1 1 1 1 NACHT domain TPR_5 PF12688.7 KEY75240.1 - 1.2e-06 28.7 30.8 0.55 10.5 0.1 7.9 1 1 5 9 9 9 4 Tetratrico peptide repeat IL34 PF15036.6 KEY75240.1 - 6.6e-05 23.0 6.0 29 4.7 0.0 8.6 1 1 11 14 14 14 0 Interleukin 34 TPR_14 PF13428.6 KEY75240.1 - 0.00034 21.2 25.1 6.1 7.9 0.0 10.8 15 0 0 15 15 7 0 Tetratricopeptide repeat DUF676 PF05057.14 KEY75240.1 - 0.0015 18.1 0.0 0.019 14.4 0.0 3.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PA28_alpha PF02251.18 KEY75240.1 - 0.0028 17.6 0.7 35 4.5 0.0 6.8 9 0 0 9 9 9 0 Proteasome activator pa28 alpha subunit PPR_1 PF12854.7 KEY75240.1 - 0.0029 17.3 20.9 47 3.8 0.0 11.5 14 0 0 14 14 14 0 PPR repeat AAA_16 PF13191.6 KEY75240.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.8 2 1 0 3 3 3 1 AAA ATPase domain AKNA PF12443.8 KEY75240.1 - 0.0041 17.7 19.3 18 6.1 0.0 11.5 15 0 0 15 15 12 0 AT-hook-containing transcription factor Hydrolase_4 PF12146.8 KEY75240.1 - 0.021 14.1 0.0 0.091 12.0 0.0 2.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KEY75240.1 - 0.027 14.2 0.0 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein DUF4404 PF14357.6 KEY75240.1 - 0.028 15.0 42.7 9.8 6.9 0.5 10.9 2 1 14 16 16 15 0 Domain of unknown function (DUF4404) PspB PF06667.12 KEY75240.1 - 0.17 12.0 15.1 46 4.2 0.0 8.1 8 0 0 8 8 6 0 Phage shock protein B TPR_6 PF13174.6 KEY75240.1 - 0.63 10.8 22.9 23 5.9 0.0 8.7 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF1319 PF07028.11 KEY75240.1 - 1.5 9.1 33.5 2.9 8.2 0.6 8.7 3 2 7 11 11 11 0 Protein of unknown function (DUF1319) DUF4477 PF14780.6 KEY75240.1 - 1.5 8.4 11.4 64 3.1 0.0 6.9 2 2 7 10 10 10 0 Domain of unknown function (DUF4477) DUF1793 PF08760.11 KEY75240.1 - 7.7 6.9 24.7 1.6e+02 2.7 0.1 10.9 7 5 9 16 16 15 0 Domain of unknown function (DUF1793) rve PF00665.26 KEY75241.1 - 3.3e-07 30.5 0.1 5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain FAM199X PF15814.5 KEY75243.1 - 0.22 10.6 1.1 0.34 9.9 0.0 1.6 1 1 1 2 2 2 0 Protein family FAM199X gag_pre-integrs PF13976.6 KEY75244.1 - 3.8e-08 33.1 0.0 7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Syntaxin PF00804.25 KEY75246.1 - 5.7e-20 71.8 16.0 8e-20 71.4 13.7 2.2 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KEY75246.1 - 8.8e-11 41.6 5.9 9.1e-11 41.6 2.1 2.9 2 0 0 2 2 2 1 SNARE domain Orf78 PF06024.12 KEY75246.1 - 0.0023 18.2 1.4 0.0034 17.7 0.2 1.9 2 0 0 2 2 2 1 Orf78 (ac78) Syntaxin_2 PF14523.6 KEY75246.1 - 0.0069 16.7 3.2 0.0069 16.7 3.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Chordopox_A33R PF05966.12 KEY75246.1 - 0.007 15.7 0.2 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Mod_r PF07200.13 KEY75246.1 - 0.015 15.4 11.1 0.49 10.5 1.2 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3671 PF12420.8 KEY75246.1 - 0.02 15.0 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Allexi_40kDa PF05549.11 KEY75246.1 - 0.021 14.4 6.1 0.025 14.1 0.6 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein AA_permease_2 PF13520.6 KEY75246.1 - 0.083 11.7 0.8 0.11 11.3 0.8 1.1 1 0 0 1 1 1 0 Amino acid permease CwsA PF10814.8 KEY75246.1 - 0.1 12.8 4.1 0.065 13.4 1.0 2.1 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA DUF2207 PF09972.9 KEY75246.1 - 0.18 10.6 0.4 0.25 10.1 0.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Vac_Fusion PF02346.16 KEY75246.1 - 0.44 10.2 2.0 24 4.7 0.0 3.3 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FUSC PF04632.12 KEY75246.1 - 0.48 8.9 10.5 0.85 8.1 10.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lebercilin PF15619.6 KEY75246.1 - 0.48 10.0 12.2 0.067 12.8 1.6 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Spectrin PF00435.21 KEY75246.1 - 0.5 10.9 9.1 2.2 8.8 0.1 3.1 3 1 0 3 3 3 0 Spectrin repeat ISG65-75 PF11727.8 KEY75246.1 - 1.5 8.0 6.5 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein GRP PF07172.11 KEY75246.1 - 3.2 8.5 9.0 1e+02 3.7 9.5 2.6 2 0 0 2 2 2 0 Glycine rich protein family TMCO5 PF14992.6 KEY75246.1 - 4.2 6.9 8.2 2.2e+02 1.2 8.2 2.1 1 1 0 1 1 1 0 TMCO5 family V-SNARE PF05008.15 KEY75246.1 - 5.7 7.4 14.6 0.43 11.0 1.2 3.9 2 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus FAM76 PF16046.5 KEY75246.1 - 9.9 5.4 10.5 9.5 5.5 2.3 2.0 1 1 1 2 2 2 0 FAM76 protein Memo PF01875.17 KEY75247.1 - 1.4e-67 227.7 0.0 1.8e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Cation_efflux PF01545.21 KEY75248.1 - 3.2e-48 164.1 18.3 2.9e-47 161.0 18.3 2.0 1 1 0 1 1 1 1 Cation efflux family DUF3395 PF11875.8 KEY75249.1 - 7.9e-25 87.6 0.0 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KEY75249.1 - 9.7e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Cyclin_N PF00134.23 KEY75250.1 - 1.3e-36 125.1 0.3 2.5e-36 124.2 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEY75250.1 - 1.5e-11 44.4 0.1 6.8e-11 42.3 0.1 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_S5 PF00333.20 KEY75252.1 - 1.6e-23 82.4 0.6 3e-23 81.6 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KEY75252.1 - 2.7e-22 78.0 0.0 5.2e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rhodanese PF00581.20 KEY75252.1 - 1.1e-15 58.1 0.0 1.1e-08 35.6 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 KEY75253.1 - 7.7e-44 147.7 10.7 9.1e-44 147.5 10.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEY75253.1 - 9.6e-22 77.0 11.7 1.4e-21 76.5 11.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEY75253.1 - 4.5e-08 33.3 16.4 1.1e-06 28.8 16.4 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEY75253.1 - 1.2e-05 25.2 10.8 0.0001 22.2 5.2 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEY75253.1 - 9.4e-05 22.2 15.4 0.00037 20.3 15.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEY75253.1 - 0.00054 19.8 7.7 0.00054 19.8 7.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEY75253.1 - 0.002 17.9 18.2 0.0036 17.1 14.3 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KEY75253.1 - 0.0021 17.8 6.0 0.0035 17.1 6.0 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KEY75253.1 - 0.0064 16.3 13.0 0.18 11.6 10.0 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-HIT PF04438.16 KEY75253.1 - 0.011 15.6 3.9 0.041 13.8 0.9 2.4 2 0 0 2 2 2 0 HIT zinc finger FANCL_C PF11793.8 KEY75253.1 - 0.012 15.8 16.3 0.15 12.2 16.3 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KEY75253.1 - 0.015 14.9 13.7 0.064 12.9 12.2 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KEY75253.1 - 0.016 15.4 10.4 0.016 15.4 10.4 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KEY75253.1 - 0.08 12.8 4.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KEY75253.1 - 0.085 12.6 11.5 0.57 10.0 9.8 2.7 2 1 0 2 2 2 0 RING-like zinc finger DUF2256 PF10013.9 KEY75253.1 - 0.1 12.8 0.6 0.1 12.8 0.6 3.6 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_5 PF14634.6 KEY75253.1 - 0.1 12.6 17.8 3.1 7.8 18.2 2.8 1 1 1 2 2 2 0 zinc-RING finger domain Pellino PF04710.14 KEY75253.1 - 0.29 9.8 3.1 0.13 10.9 0.3 1.7 2 0 0 2 2 2 0 Pellino YacG PF03884.14 KEY75253.1 - 0.34 10.7 9.0 0.18 11.5 0.9 2.8 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-HC5HC2H_2 PF13832.6 KEY75253.1 - 0.71 10.1 10.8 0.38 10.9 5.7 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 KEY75253.1 - 1.2 9.2 13.6 1.3 9.1 6.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon RINGv PF12906.7 KEY75253.1 - 1.3 9.2 15.5 1.1 9.4 12.9 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KEY75253.1 - 2.5 8.5 14.0 2.1 8.7 11.1 2.1 1 1 1 2 2 2 0 RING-like domain PHD PF00628.29 KEY75253.1 - 2.7 7.9 14.8 13 5.7 14.8 2.1 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KEY75253.1 - 4.7 7.5 12.5 4.6 7.6 6.9 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain Pkinase PF00069.25 KEY75254.1 - 4.9e-57 193.3 0.0 6.8e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEY75254.1 - 2.7e-26 92.4 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEY75254.1 - 6.4e-07 29.0 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEY75254.1 - 8.6e-05 22.6 0.0 0.57 10.0 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KEY75254.1 - 0.0036 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 KEY75254.1 - 0.19 11.3 0.0 0.93 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 KEY75254.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase UQ_con PF00179.26 KEY75255.1 - 7.7e-49 164.9 0.0 9.6e-49 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEY75255.1 - 5.4e-05 22.9 0.0 7.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEY75255.1 - 0.002 18.4 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KEY75255.1 - 0.028 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Ribosomal_L31e PF01198.19 KEY75256.1 - 1.9e-39 133.8 0.7 2.5e-39 133.4 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.19 KEY75257.1 - 3.7e-11 43.3 0.0 8.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.27 KEY75258.1 - 9.9e-06 26.0 0.0 3.8e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KEY75258.1 - 0.00095 19.0 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain HMA PF00403.26 KEY75259.1 - 6.5e-49 164.2 0.3 1.5e-12 47.8 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KEY75259.1 - 1e-48 165.3 0.2 2.7e-48 163.9 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEY75259.1 - 3.9e-40 138.4 2.0 8.9e-40 137.2 2.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEY75259.1 - 3.8e-06 26.8 0.8 6.3e-05 22.8 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAM70 PF14967.6 KEY75259.1 - 0.051 13.0 0.7 9.2 5.6 0.0 2.8 3 0 0 3 3 3 0 FAM70 protein HAD PF12710.7 KEY75259.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KEY75259.1 - 3.1 7.9 10.8 3 7.9 3.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) TPT PF03151.16 KEY75261.1 - 4.7e-34 118.1 17.6 5.7e-34 117.8 17.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KEY75261.1 - 3.3e-06 26.5 19.0 1.6e-05 24.3 18.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEY75261.1 - 0.017 15.3 33.1 0.23 11.6 9.2 2.2 2 0 0 2 2 2 0 EamA-like transporter family DUF155 PF02582.14 KEY75262.1 - 4.9e-57 192.8 0.1 7.5e-57 192.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 KEY75262.1 - 0.047 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF2561 PF10812.8 KEY75262.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) LBP_BPI_CETP_C PF02886.17 KEY75262.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain RasGAP PF00616.19 KEY75263.1 - 6.5e-51 173.0 0.0 2e-50 171.4 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KEY75263.1 - 9e-49 165.1 7.7 9.5e-49 165.1 5.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KEY75263.1 - 4.8e-13 47.6 45.0 0.027 14.3 3.6 13.7 14 0 0 14 14 14 7 IQ calmodulin-binding motif CH PF00307.31 KEY75263.1 - 5.5e-12 45.8 0.1 3e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain Sulfatase PF00884.23 KEY75264.1 - 4.3e-57 193.9 0.0 5.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KEY75264.1 - 1.1e-25 89.1 2.5 1.4e-25 88.9 0.7 2.1 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KEY75264.1 - 2.2e-09 37.4 0.2 3.7e-08 33.3 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KEY75264.1 - 8.3e-06 24.7 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KEY75264.1 - 6.7e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KEY75264.1 - 0.036 13.1 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3131 PF11329.8 KEY75264.1 - 0.057 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) Med8 PF10232.9 KEY75265.1 - 3.8e-36 124.8 6.5 5.5e-36 124.3 6.5 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.6 KEY75265.1 - 0.018 14.4 0.6 0.024 14.0 0.6 1.2 1 0 0 1 1 1 0 YpeB sporulation AvrB_AvrC PF05394.11 KEY75265.1 - 0.035 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein Complex1_LYR_1 PF13232.6 KEY75265.1 - 0.056 14.0 0.5 11 6.7 0.1 2.5 1 1 1 2 2 2 0 Complex1_LYR-like Sporozoite_P67 PF05642.11 KEY75265.1 - 0.12 10.4 1.3 0.16 10.0 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GFA PF04828.14 KEY75268.1 - 3e-07 30.7 3.4 2.3e-05 24.7 3.4 2.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNase_P_p30 PF01876.16 KEY75270.1 - 2e-55 187.6 0.0 3.2e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DDE_Tnp_1_7 PF13843.6 KEY75271.1 - 4e-24 85.6 0.0 5.2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 MFMR_assoc PF16596.5 KEY75271.1 - 0.14 12.6 9.3 0.28 11.7 9.3 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR WD40 PF00400.32 KEY75272.1 - 1.8e-112 364.0 46.1 6.2e-11 42.7 0.1 11.7 10 1 1 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY75272.1 - 6.9e-36 122.4 0.0 4.5e-06 26.9 0.0 6.4 2 1 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY75272.1 - 4.4e-16 58.7 6.8 1.1 8.1 0.0 9.9 1 1 9 10 10 10 6 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEY75272.1 - 1.1e-15 57.8 0.0 0.14 11.5 0.0 7.8 2 2 2 6 6 6 5 WD40-like domain Nup160 PF11715.8 KEY75272.1 - 1.7e-12 46.8 14.7 0.38 9.4 0.1 8.4 1 1 8 9 9 9 5 Nucleoporin Nup120/160 NACHT PF05729.12 KEY75272.1 - 1.2e-10 41.5 0.0 3.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY75272.1 - 3e-08 34.2 0.0 1.1e-07 32.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain LydB PF16084.5 KEY75272.1 - 0.00039 20.2 1.6 17 5.2 0.0 6.3 3 2 5 8 8 8 0 LydA-holin antagonist AAA PF00004.29 KEY75272.1 - 0.0045 17.4 0.1 0.022 15.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KEY75272.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KEY75272.1 - 0.033 14.7 0.1 0.09 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEY75272.1 - 0.034 13.4 1.0 0.15 11.3 0.3 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KEY75272.1 - 0.04 14.2 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEY75272.1 - 0.045 13.7 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.14 KEY75272.1 - 0.047 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Cytidylate_kin PF02224.18 KEY75272.1 - 0.059 13.1 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase COG6 PF06419.11 KEY75272.1 - 0.076 11.2 0.3 0.15 10.2 0.3 1.4 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4072 PF13284.6 KEY75272.1 - 0.39 11.2 8.4 1.8e+02 2.6 0.0 6.9 8 0 0 8 8 8 0 Domain of unknown function (DUF4072) Lactonase PF10282.9 KEY75273.1 - 1.1e-05 24.9 0.0 1.2e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NPR2 PF06218.11 KEY75274.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DNA_pol_phi PF04931.13 KEY75275.1 - 2.2 6.3 17.2 3.5 5.6 17.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ferric_reduct PF01794.19 KEY75278.1 - 1.3e-16 60.8 5.3 1.3e-16 60.8 5.3 2.0 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEY75278.1 - 4.4e-14 52.5 0.0 2.3e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KEY75278.1 - 5.4e-13 49.4 0.2 7.4e-10 39.2 0.2 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain HTH_Tnp_4 PF13613.6 KEY75278.1 - 0.12 12.1 0.1 0.45 10.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF3723 PF12520.8 KEY75279.1 - 1.8e-126 422.9 0.8 2.2e-124 415.9 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) L31 PF09784.9 KEY75279.1 - 0.55 10.7 4.4 4.8 7.7 3.4 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 SIR2 PF02146.17 KEY75281.1 - 1.3e-08 35.0 0.1 1.1e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 Sir2 family DUF1796 PF08795.10 KEY75281.1 - 0.054 13.5 0.2 0.078 12.9 0.2 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Patatin PF01734.22 KEY75282.1 - 2.4e-08 34.4 0.1 4.5e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 KEY75282.1 - 0.064 13.3 1.9 0.3 11.1 1.9 2.2 1 0 0 1 1 1 0 RING-type zinc-finger Phosducin PF02114.16 KEY75283.1 - 9.8e-12 44.4 0.2 3.6e-11 42.5 0.2 1.7 1 1 0 1 1 1 1 Phosducin Cupin_1 PF00190.22 KEY75284.1 - 4.3e-14 52.4 0.4 6.8e-14 51.7 0.4 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KEY75284.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Spc7 PF08317.11 KEY75285.1 - 6e-05 22.1 11.0 6e-05 22.1 11.0 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Nup88 PF10168.9 KEY75285.1 - 0.0013 16.6 9.3 0.0013 16.6 9.3 2.1 1 1 1 2 2 2 1 Nuclear pore component UPF0242 PF06785.11 KEY75285.1 - 0.0086 16.2 10.2 0.0086 16.2 10.2 2.4 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Cep57_MT_bd PF06657.13 KEY75285.1 - 0.077 13.5 23.5 5.5 7.5 7.0 5.2 3 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 NYD-SP28_assoc PF14775.6 KEY75285.1 - 0.12 12.5 14.3 0.37 10.9 1.2 4.1 3 1 1 4 4 4 0 Sperm tail C-terminal domain ATG16 PF08614.11 KEY75285.1 - 0.29 11.4 37.6 16 5.7 20.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 KEY75285.1 - 1 9.4 0.0 1 9.4 0.0 5.4 1 1 2 4 4 4 0 Prefoldin subunit DUF1664 PF07889.12 KEY75285.1 - 1.1 9.3 18.1 0.74 9.9 1.6 4.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Hemerythrin PF01814.23 KEY75285.1 - 1.2 9.8 8.1 0.86 10.2 1.4 3.2 1 1 3 4 4 4 0 Hemerythrin HHE cation binding domain NAD_binding_6 PF08030.12 KEY75287.1 - 1.8e-11 44.4 0.1 3.6e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEY75287.1 - 2.4e-07 30.8 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KEY75287.1 - 0.054 13.6 0.4 0.11 12.6 0.2 1.7 2 0 0 2 2 2 0 Ferric reductase like transmembrane component HPP PF04982.13 KEY75287.1 - 0.097 12.9 1.2 0.78 9.9 1.2 2.1 1 1 0 1 1 1 0 HPP family Glyco_hydro_16 PF00722.21 KEY75288.1 - 7.7e-12 45.0 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEY75288.1 - 0.00027 19.5 1.3 0.11 10.9 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Importin_rep PF18773.1 KEY75288.1 - 0.13 12.0 0.3 0.34 10.6 0.3 1.7 1 0 0 1 1 1 0 Importin 13 repeat Velvet PF11754.8 KEY75289.1 - 6.7e-26 91.7 5.1 6.6e-17 62.3 0.0 2.0 1 1 1 2 2 2 2 Velvet factor HET PF06985.11 KEY75290.1 - 2.4e-12 47.5 0.9 2.4e-12 47.5 0.9 3.2 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_25 PF13481.6 KEY75290.1 - 0.0043 16.6 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEY75290.1 - 0.0055 15.9 0.0 0.048 12.8 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain Ses_B PF17046.5 KEY75290.1 - 0.14 12.2 1.9 0.25 11.3 1.9 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein WRNPLPNID PF15017.6 KEY75290.1 - 0.19 12.6 5.2 5.2 8.0 2.7 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box zf-RING_2 PF13639.6 KEY75292.1 - 0.075 13.4 7.6 0.13 12.6 7.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF1098 PF06497.11 KEY75292.1 - 0.25 11.8 1.6 12 6.5 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1098) DUF2730 PF10805.8 KEY75292.1 - 0.82 9.8 4.5 7.6 6.7 0.3 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) zf-C3HC4_2 PF13923.6 KEY75292.1 - 0.88 9.5 5.0 1.8 8.5 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HU-CCDC81_bac_2 PF18175.1 KEY75292.1 - 1.4 8.8 5.7 6.8 6.6 0.1 4.0 2 1 3 5 5 5 0 CCDC81-like prokaryotic HU domain 2 SUR7 PF06687.12 KEY75293.1 - 2.6e-25 89.3 8.3 3.2e-25 89.0 8.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Methyltransf_33 PF10017.9 KEY75294.1 - 2.4e-34 118.9 0.0 2.8e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF3464 PF11947.8 KEY75298.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SDA1 PF05285.12 KEY75298.1 - 3.6 6.9 16.3 6 6.2 16.3 1.3 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 KEY75298.1 - 6.9 5.6 19.6 0.86 8.6 10.1 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Barwin PF00967.17 KEY75299.1 - 0.096 12.5 0.2 3.8 7.4 0.0 2.2 1 1 1 2 2 2 0 Barwin family PAP2 PF01569.21 KEY75302.1 - 3.7e-06 26.8 0.4 6.9e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 PAP2 superfamily Cu-oxidase PF00394.22 KEY75303.1 - 8.6e-16 58.5 0.3 4.1e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEY75303.1 - 1.4e-05 25.1 1.0 6.8e-05 22.9 0.1 2.3 3 0 0 3 3 3 1 Multicopper oxidase Tannase PF07519.11 KEY75304.1 - 2.3e-66 224.6 0.4 3.1e-66 224.2 0.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEY75304.1 - 0.0028 17.2 0.2 0.24 10.9 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family E1_FCCH PF16190.5 KEY75305.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain AtuA PF07287.11 KEY75306.1 - 3.9e-91 305.4 0.0 4.9e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Oxidored_FMN PF00724.20 KEY75307.1 - 9e-84 281.6 0.0 1.2e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bac_luciferase PF00296.20 KEY75307.1 - 1.4e-20 74.0 0.2 3.4e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sugarporin_N PF11471.8 KEY75309.1 - 0.028 14.4 0.2 0.065 13.2 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Zn_clus PF00172.18 KEY75309.1 - 0.096 12.8 3.1 0.17 12.0 3.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEY75310.1 - 3.9e-25 88.4 0.0 5.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 KEY75311.1 - 0.0021 17.9 0.0 0.33 10.9 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide deacetylase ADH_N PF08240.12 KEY75312.1 - 8.9e-10 38.4 0.1 1.6e-08 34.4 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEY75312.1 - 1.7e-07 31.3 0.1 2.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.15 KEY75313.1 - 1.2e-69 235.2 36.0 2.4e-64 217.7 29.1 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3237 PF11578.8 KEY75314.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Methyltransf_25 PF13649.6 KEY75316.1 - 4e-05 24.2 0.0 6.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEY75316.1 - 0.00021 22.0 0.0 0.00035 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEY75316.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 KEY75316.1 - 0.046 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase KR PF08659.10 KEY75317.1 - 1.9e-36 125.7 0.0 3.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KEY75317.1 - 0.00025 20.6 0.1 0.00068 19.1 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75317.1 - 0.019 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_61 PF03443.14 KEY75319.1 - 2.2e-59 200.9 0.0 3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEY75319.1 - 1.3e-11 44.3 12.1 3.7e-11 42.8 12.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain NPCBM_assoc PF10633.9 KEY75319.1 - 0.0077 16.5 0.2 0.24 11.7 0.0 2.6 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase ATP-synt_J PF04911.12 KEY75320.1 - 0.0078 15.8 0.1 0.34 10.5 0.1 2.5 2 0 0 2 2 2 1 ATP synthase j chain ESCRT-II PF05871.12 KEY75320.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit Cytotoxic PF09000.10 KEY75320.1 - 0.23 11.8 0.7 0.45 10.9 0.7 1.4 1 0 0 1 1 1 0 Cytotoxic F-box-like PF12937.7 KEY75321.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 F-box-like SnoaL_2 PF12680.7 KEY75323.1 - 0.0058 17.2 0.1 0.008 16.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Apo-CIII PF05778.12 KEY75323.1 - 0.011 15.3 0.0 0.06 13.0 0.0 2.1 1 1 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) KR PF08659.10 KEY75324.1 - 4.7e-28 98.3 0.0 6.9e-19 68.4 0.0 2.1 1 1 1 2 2 2 2 KR domain adh_short PF00106.25 KEY75324.1 - 0.065 12.7 0.2 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_3 PF07859.13 KEY75325.1 - 1.5e-07 31.5 0.4 1.4e-05 25.1 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold adh_short PF00106.25 KEY75326.1 - 6.5e-29 100.8 0.1 8.1e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEY75326.1 - 6.7e-19 68.4 2.2 4.8e-18 65.6 2.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEY75326.1 - 6.4e-13 49.0 0.2 1e-12 48.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEY75326.1 - 1.8e-05 24.0 0.0 4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEY75326.1 - 0.0027 17.2 2.4 0.062 12.8 2.4 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 KEY75326.1 - 0.075 13.5 3.7 8.4 6.8 3.7 2.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Zn_clus PF00172.18 KEY75328.1 - 0.01 15.9 8.6 0.12 12.5 0.5 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FTA4 PF13093.6 KEY75328.1 - 0.012 15.5 0.2 0.012 15.5 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Muted PF14942.6 KEY75328.1 - 0.013 15.9 0.6 0.018 15.4 0.6 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein APG6_N PF17675.1 KEY75328.1 - 0.024 15.1 4.1 0.031 14.8 4.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region WD40 PF00400.32 KEY75329.1 - 1.7e-153 493.8 35.0 4.1e-11 43.2 0.0 15.1 14 1 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEY75329.1 - 3.9e-57 190.5 0.0 9.3e-08 32.3 0.0 8.2 3 3 7 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEY75329.1 - 9.4e-41 139.8 16.3 0.0085 15.1 0.0 14.1 1 1 13 14 14 14 14 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEY75329.1 - 2.2e-27 95.9 26.9 0.11 11.1 0.0 13.9 1 1 13 14 14 14 12 Nucleoporin Nup120/160 NACHT PF05729.12 KEY75329.1 - 8.8e-10 38.7 0.0 2.7e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEY75329.1 - 4.9e-07 30.3 0.0 1.6e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PHZA_PHZB PF03284.13 KEY75329.1 - 4.7e-06 26.3 14.4 12 5.5 0.1 10.9 11 3 2 14 14 14 0 Phenazine biosynthesis protein A/B DUF1481 PF07356.12 KEY75329.1 - 5.4e-06 26.3 16.2 18 5.0 0.1 10.6 12 2 2 14 14 14 0 Protein of unknown function (DUF1481) WD40_like PF17005.5 KEY75329.1 - 1.9e-05 24.2 0.0 1.5 8.1 0.0 5.4 3 2 4 7 7 7 1 WD40-like domain Cytochrom_D1 PF02239.16 KEY75329.1 - 0.0025 16.4 10.7 3.5 6.0 0.1 5.0 1 1 4 5 5 5 2 Cytochrome D1 heme domain ATPase_2 PF01637.18 KEY75329.1 - 0.0036 17.2 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KEY75329.1 - 0.018 14.3 0.6 0.055 12.7 0.3 1.6 1 1 1 2 2 2 0 KAP family P-loop domain HTH_20 PF12840.7 KEY75329.1 - 0.038 14.1 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_18 PF13238.6 KEY75329.1 - 0.061 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEY75329.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 KEY75329.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase PIF1 PF05970.14 KEY75329.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.20 KEY75329.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stachybotrys_chartarum_IBT_7711-S7711v1/GCA_000730325.1_S7711v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stachybotrys_chartarum_IBT_7711-S7711v1/GCA_000730325.1_S7711v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stachybotrys_chartarum_IBT_7711-S7711v1/GCA_000730325.1_S7711v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stachybotrys_chartarum_IBT_7711-S7711v1/GCA_000730325.1_S7711v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:24:27 2019 # [ok]